ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0030198 extracellular matrix organization 56/504 301/18722 5.80246831358448e-31 1.41914837829295e-27 COL1A2/COL3A1/COL1A1/LUM/EGFL6/NID1/MYH11/COL5A1/PXDN/AEBP1/NID2/ELN/COL18A1/ANTXR1/ADAMTS5/OLFML2B/DDR2/COL5A3/COL12A1/ADAMTS2/EFEMP2/ADAMTS9/PDGFRA/EMILIN1/COL5A2/CTSK/CRISPLD2/COL27A1/FBLN2/GAS6/COL15A1/COL4A1/COL8A1/FBLN5/TGFB2/COL4A2/MMP2/FKBP10/SULF2/ITGB1/EXT1/LAMC1/ETS1/CAV1/SERPINH1/LAMB2/BMP1/COL14A1/CAV2/LAMB1/P3H4/TGFBI/QSOX1/CCDC80/ADAMTS1/CRTAP 56 GO:0043062 extracellular structure organization 56/504 302/18722 6.95354711616357e-31 1.41914837829295e-27 COL1A2/COL3A1/COL1A1/LUM/EGFL6/NID1/MYH11/COL5A1/PXDN/AEBP1/NID2/ELN/COL18A1/ANTXR1/ADAMTS5/OLFML2B/DDR2/COL5A3/COL12A1/ADAMTS2/EFEMP2/ADAMTS9/PDGFRA/EMILIN1/COL5A2/CTSK/CRISPLD2/COL27A1/FBLN2/GAS6/COL15A1/COL4A1/COL8A1/FBLN5/TGFB2/COL4A2/MMP2/FKBP10/SULF2/ITGB1/EXT1/LAMC1/ETS1/CAV1/SERPINH1/LAMB2/BMP1/COL14A1/CAV2/LAMB1/P3H4/TGFBI/QSOX1/CCDC80/ADAMTS1/CRTAP 56 GO:0045229 external encapsulating structure organization 56/504 304/18722 9.96359732010031e-31 1.41914837829295e-27 COL1A2/COL3A1/COL1A1/LUM/EGFL6/NID1/MYH11/COL5A1/PXDN/AEBP1/NID2/ELN/COL18A1/ANTXR1/ADAMTS5/OLFML2B/DDR2/COL5A3/COL12A1/ADAMTS2/EFEMP2/ADAMTS9/PDGFRA/EMILIN1/COL5A2/CTSK/CRISPLD2/COL27A1/FBLN2/GAS6/COL15A1/COL4A1/COL8A1/FBLN5/TGFB2/COL4A2/MMP2/FKBP10/SULF2/ITGB1/EXT1/LAMC1/ETS1/CAV1/SERPINH1/LAMB2/BMP1/COL14A1/CAV2/LAMB1/P3H4/TGFBI/QSOX1/CCDC80/ADAMTS1/CRTAP 56 GO:0031589 cell-substrate adhesion 52/504 363/18722 3.04393784082623e-23 3.25168659846262e-20 COL3A1/COL1A1/EGFL6/ITGA1/THBS1/NID1/THY1/LAMC3/NID2/ANTXR1/APOD/EDIL3/COL5A3/EFEMP2/ADAMTS9/EMILIN1/FLNA/LIMS2/FBLN2/GAS6/AXL/COL8A1/FBLN5/LGALS1/DLC1/PEAK1/JAG1/RRAS/VCL/ITGB1/MDK/LAMC1/MYADM/SORBS3/RIN2/LIMS1/ACTN4/LAMB2/ACTN1/LAMB1/FERMT2/CCDC80/MAP4K4/PARVA/MKLN1/ROCK2/ADAM9/PIK3R1/MACF1/PTEN/PTPRA/ACTG1 52 GO:0030199 collagen fibril organization 22/504 61/18722 1.53975788136607e-19 1.31587708541545e-16 COL1A2/COL3A1/COL1A1/LUM/COL5A1/PXDN/AEBP1/DDR2/COL5A3/COL12A1/ADAMTS2/EFEMP2/EMILIN1/COL5A2/TGFB2/FKBP10/EXT1/SERPINH1/BMP1/COL14A1/P3H4/CRTAP 22 GO:0071559 response to transforming growth factor beta 37/504 256/18722 5.84441902706829e-17 4.16220041711046e-14 COL1A2/COL3A1/COL1A1/THBS1/LTBP2/TGFB1I1/MYOCD/EMILIN1/PDE3A/WNT2/LRRC32/LTBP4/TGFB2/COL4A2/ZEB2/TWSG1/MEF2C/CAV1/SPRY1/SOX6/LIMS1/NR3C1/LTBP1/FBN1/CAV2/CITED2/HIPK2/SMAD5/FERMT2/ZFP36L1/HTRA1/ZFHX3/JUN/ROCK2/ADAM9/STAT3/ZMIZ1 37 GO:0010810 regulation of cell-substrate adhesion 33/504 221/18722 1.11196482901119e-15 6.0815165956909e-13 COL1A1/EGFL6/THBS1/NID1/THY1/APOD/EDIL3/EFEMP2/EMILIN1/FLNA/LIMS2/FBLN2/COL8A1/LGALS1/DLC1/PEAK1/JAG1/RRAS/VCL/MDK/MYADM/RIN2/LIMS1/ACTN4/FERMT2/CCDC80/MAP4K4/ROCK2/PIK3R1/MACF1/PTEN/PTPRA/ACTG1 33 GO:0071560 cellular response to transforming growth factor beta stimulus 35/504 250/18722 1.13859426083612e-15 6.0815165956909e-13 COL1A2/COL3A1/COL1A1/THBS1/LTBP2/TGFB1I1/MYOCD/EMILIN1/PDE3A/WNT2/LRRC32/LTBP4/TGFB2/COL4A2/ZEB2/TWSG1/MEF2C/CAV1/SPRY1/SOX6/LIMS1/NR3C1/LTBP1/FBN1/CAV2/CITED2/HIPK2/SMAD5/FERMT2/ZFP36L1/HTRA1/JUN/ADAM9/STAT3/ZMIZ1 35 GO:0060537 muscle tissue development 43/504 403/18722 1.28153619757625e-14 6.08444908027034e-12 DCN/IGFBP5/MYLK/MYH11/PDGFRB/GJC1/ELN/TBX2/MYOCD/EFEMP2/ADAMTS9/PDGFRA/WNT2/MEIS1/TPM1/TGFB2/SORBS2/NR2F2/PDLIM5/SGCB/MEF2C/ITGB1/SLC8A1/MYL6/CAV1/SOX6/EGR1/IGF2/CFL2/CSRP1/CAV2/PKD2/CITED2/SMAD5/NOTCH2/SVIL/PRKAR1A/DDX17/MEF2A/ATF3/NR4A1/PTEN/AKAP13 43 GO:0042060 wound healing 44/504 422/18722 1.42936621780242e-14 6.10768184866975e-12 COL3A1/COL1A1/DCN/SPARC/MYL9/THBS1/MYLK/COL5A1/PDGFRB/MCAM/WFDC1/PRKG1/PDGFRA/FLNA/GAS6/AXL/TPM1/TFPI/TIMP1/TGFB2/FKBP10/VCL/ITGB1/EXT1/ETS1/ACTB/IL6ST/SERPING1/MYH9/CAV1/PTK7/DST/CNN2/CSRP1/FERMT2/NOTCH2/HSPB1/TLN1/PDGFA/XBP1/MACF1/PTEN/ACTG1/DCBLD2 44 GO:0001503 ossification 42/504 408/18722 9.06672869149575e-14 3.52201197261467e-11 COL1A2/COL1A1/COL6A1/IGFBP5/SPARC/MGP/CDH11/CTHRC1/DDR2/HAND2/ENPP1/COL5A2/CTSK/HGF/VCAN/TGFB2/MMP2/PDLIM7/TWSG1/JAG1/GPC3/IFITM1/MEF2C/SLC8A1/MDK/CLEC11A/EXT1/TPM4/IL6ST/IGF2/BMP1/SMAD5/FERMT2/HDAC7/ISG15/WWTR1/BCAP29/BMPR2/RRBP1/PBX1/DHRS3/CRIM1 42 GO:0003012 muscle system process 44/504 452/18722 1.63859114530535e-13 5.83474996990813e-11 ACTA2/IGFBP5/TPM2/MYL9/MYLK/MYH11/CRYAB/GATM/LMOD1/GJC1/EDNRA/HSPB6/FXYD1/TBX2/CNN1/HAND2/PRKG1/MYOCD/FLNA/TPM1/CALD1/ARHGAP42/FOXO1/SORBS2/SULF2/SLMAP/PDLIM5/LMCD1/PPP1R12B/SLC8A1/EDNRB/TPM4/IL6ST/MYL6/ATP2B4/CAV1/GSN/SMAD5/CALM2/ROCK2/MEF2A/FBXO32/NR4A1/AKAP13 44 GO:0007160 cell-matrix adhesion 31/504 233/18722 2.07528062785943e-13 6.82128778680256e-11 COL3A1/ITGA1/THBS1/NID1/THY1/NID2/APOD/COL5A3/EFEMP2/ADAMTS9/EMILIN1/FBLN5/DLC1/PEAK1/JAG1/RRAS/VCL/ITGB1/RIN2/LIMS1/ACTN1/FERMT2/MAP4K4/MKLN1/ROCK2/ADAM9/PIK3R1/MACF1/PTEN/PTPRA/ACTG1 31 GO:0007015 actin filament organization 42/504 441/18722 1.24248265513136e-12 3.79223456098307e-10 TPM2/SYNPO2/LMOD1/PLS3/ELN/SEMA5A/PLEKHH2/MYO1B/FLNA/TPM1/DLC1/CALD1/MARCKS/SORBS2/HIP1/LPAR1/MYADM/SORBS3/TMSB4X/TPM4/TJP1/MARCKSL1/EPS8/SPTBN1/LIMA1/ENAH/GSN/DSTN/CFL2/ACTN1/CDC42EP3/FERMT2/NCKAP1/MPRIP/SVIL/RHOB/RND3/HSP90B1/ROCK2/FAT1/PIK3R1/ACTG1 42 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 37/504 355/18722 1.97506475488624e-12 5.62630113175261e-10 COL1A2/COL3A1/THBS1/LTBP2/TGFB1I1/MYOCD/EMILIN1/LRRC32/LTBP4/TGFB2/VIM/ZEB2/TWSG1/GPC3/EXT1/FSTL1/CAV1/SPTBN1/SPRY1/EGR1/LTBP1/FBN1/CAV2/CITED2/HIPK2/SMAD5/FERMT2/NOTCH2/HTRA1/RBPMS/JUN/WWTR1/ADAM9/STAT3/ZMIZ1/BMPR2/CRIM1 37 GO:0032970 regulation of actin filament-based process 39/504 396/18722 2.90285520717794e-12 7.75243768766958e-10 SYNPO2/PDGFRB/LMOD1/ELN/SEMA5A/PDGFRA/PLEKHH2/FLNA/TPM1/DLC1/LPAR1/MDK/MYADM/SORBS3/TMSB4X/TJP1/MYH9/EPS8/CAV1/SPTBN1/LIMA1/RHOQ/CNN2/GSN/DSTN/CFL2/CDC42EP3/FERMT2/NOTCH2/NCKAP1/SVIL/RHOB/RND3/PDGFA/ROCK2/PIK3R1/TAOK1/ACTG1/AKAP13 39 GO:0014706 striated muscle tissue development 38/504 384/18722 4.82534888139062e-12 1.21286563354012e-09 DCN/MYH11/PDGFRB/GJC1/ELN/TBX2/MYOCD/ADAMTS9/PDGFRA/WNT2/MEIS1/TPM1/TGFB2/SORBS2/NR2F2/PDLIM5/SGCB/MEF2C/ITGB1/SLC8A1/MYL6/CAV1/SOX6/EGR1/IGF2/CFL2/CAV2/CITED2/SMAD5/NOTCH2/SVIL/PRKAR1A/DDX17/MEF2A/ATF3/NR4A1/PTEN/AKAP13 38 GO:0048844 artery morphogenesis 17/504 74/18722 8.72908227091914e-12 2.07218714131319e-09 MYLK/PDGFRB/TBX2/HAND2/MYOCD/EFEMP2/ADAMTS9/TGFB2/FKBP10/JAG1/MDK/SOX4/PKD2/CITED2/ZMIZ1/BMPR2/AKT3 17 GO:0032956 regulation of actin cytoskeleton organization 36/504 357/18722 1.04061144813521e-11 2.34028037783249e-09 SYNPO2/PDGFRB/LMOD1/ELN/SEMA5A/PDGFRA/PLEKHH2/FLNA/TPM1/DLC1/LPAR1/MDK/MYADM/SORBS3/TMSB4X/TJP1/EPS8/SPTBN1/LIMA1/RHOQ/GSN/DSTN/CFL2/CDC42EP3/FERMT2/NOTCH2/NCKAP1/SVIL/RHOB/RND3/PDGFA/ROCK2/PIK3R1/TAOK1/ACTG1/AKAP13 36 GO:0001667 ameboidal-type cell migration 42/504 475/18722 1.40355691810113e-11 2.99869935552307e-09 DCN/SPARC/THBS1/AKAP12/SEMA5A/ADGRA2/DDR2/HAND2/ADAMTS9/KANK2/TIMP1/TGFB2/ZEB2/RRAS/NR2F2/GPC3/FGFR1/MEF2C/ITGB1/SLC8A1/EDNRB/FSTL1/TMSB4X/ETS1/ATP2B4/MYH9/RIN2/PLXND1/HDAC7/MAP4K4/HSPB1/RHOB/ARID5B/STARD13/ROCK2/AMOTL2/ADAM9/MACF1/NR4A1/PTEN/BMPR2/AKT3 42 GO:0031032 actomyosin structure organization 26/504 196/18722 2.00298319498515e-11 4.07559390103407e-09 MYH11/PDGFRB/LMOD1/ELN/CNN1/PDGFRA/TPM1/DLC1/LPAR1/EPB41L2/ITGB1/SORBS3/TJP1/MYH9/CDC42BPA/CNN2/CFL2/CSRP1/FERMT2/PRKAR1A/CNN3/ROCK2/MEF2A/PIK3R1/ACTG1/AKAP13 26 GO:0150115 cell-substrate junction organization 19/504 101/18722 2.2427836043159e-11 4.35609742783719e-09 THBS1/THY1/APOD/DLC1/PEAK1/VCL/LAMC1/DST/LIMS1/ACTN1/FERMT2/MAP4K4/TLN1/ROCK2/PIK3R1/MACF1/PTEN/PTPRA/ACTG1 19 GO:0007179 transforming growth factor beta receptor signaling pathway 26/504 198/18722 2.5269247183624e-11 4.69458666154893e-09 COL1A2/COL3A1/THBS1/LTBP2/TGFB1I1/MYOCD/EMILIN1/LRRC32/LTBP4/TGFB2/ZEB2/TWSG1/CAV1/SPRY1/LTBP1/FBN1/CAV2/CITED2/HIPK2/SMAD5/FERMT2/HTRA1/JUN/ADAM9/STAT3/ZMIZ1 26 GO:0072001 renal system development 32/504 302/18722 4.17570115285112e-11 7.26763073490507e-09 ACTA2/DCN/NID1/PDGFRB/AGTR1/MYOCD/PDGFRA/KANK2/COL4A1/TGFB2/NFIA/SULF2/JAG1/GPC3/MEF2C/EXT1/SOX4/SPRY1/EGR1/PTK7/PLXND1/FBN1/LAMB2/PKD2/SMAD5/NOTCH2/ARID5B/ADAMTS1/PDGFA/WWTR1/ARL3/PBX1 32 GO:0001655 urogenital system development 34/504 338/18722 4.25206572367486e-11 7.26763073490507e-09 ACTA2/DCN/NID1/PDGFRB/AGTR1/MYOCD/PDGFRA/KANK2/COL4A1/TGFB2/NFIA/SULF2/JAG1/GPC3/MEF2C/CRIP1/EXT1/SOX4/SPRY1/EGR1/PTK7/PLXND1/FBN1/LAMB2/PKD2/SMAD5/NOTCH2/ARID5B/ADAMTS1/PDGFA/WWTR1/ARL3/PTEN/PBX1 34 GO:0007044 cell-substrate junction assembly 18/504 95/18722 6.67877907732486e-11 1.0976316537465e-08 THBS1/THY1/APOD/DLC1/PEAK1/VCL/LAMC1/DST/LIMS1/ACTN1/FERMT2/MAP4K4/TLN1/ROCK2/MACF1/PTEN/PTPRA/ACTG1 18 GO:0060485 mesenchyme development 31/504 291/18722 7.39523946977527e-11 1.16005360786315e-08 COL1A1/ACTA2/ACTG2/PDGFRB/SEMA5A/EDNRA/TGFB1I1/TBX2/HAND2/WNT2/HGF/FLNA/TGFB2/JAG1/FGFR1/MEF2C/MDK/EXT1/EDNRB/SPRY1/PTK7/PKD2/CITED2/FERMT2/ZFP36L1/DDX17/WWTR1/S100A4/ROCK2/PTEN/BMPR2 31 GO:0007517 muscle organ development 33/504 327/18722 7.60156822376978e-11 1.16005360786315e-08 TAGLN/DCN/COL6A3/MYLK/CRYAB/LAMA2/ELN/MYOCD/EFEMP2/FHL1/WNT2/TPM1/TGFB2/NR2F2/SGCB/MEF2C/MYL6/CAV1/SOX6/EGR1/IGF2/CFL2/CAV2/CITED2/SVIL/ARID5B/ZFHX3/DDX17/MEF2A/XBP1/ATF3/NR4A1/TCF12 33 GO:0090130 tissue migration 35/504 365/18722 8.29262107584407e-11 1.19200226480736e-08 ACTA2/DCN/SPARC/THBS1/ACTG2/SEMA5A/ADGRA2/ADAMTS9/KANK2/TGFB2/ZEB2/RRAS/NR2F2/FGFR1/MEF2C/ITGB1/FSTL1/TMSB4X/ETS1/ATP2B4/MYH9/RIN2/PLXND1/HDAC7/MAP4K4/HSPB1/RHOB/STARD13/ROCK2/ADAM9/MACF1/NR4A1/PTEN/BMPR2/AKT3 35 GO:0042692 muscle cell differentiation 36/504 384/18722 8.36884342247151e-11 1.19200226480736e-08 IGFBP5/MYH11/PDGFRB/LMOD1/ADAMTS5/TBX2/EHD2/MYOCD/EFEMP2/PDGFRA/TPM1/SORBS2/PDLIM5/SGCB/MEF2C/CD81/ITGB1/SLC8A1/EDNRB/MYH9/SYNE1/SOX6/ADAM12/ACTN4/IGF2/CFL2/CSRP1/CAV2/ACTN1/PRKAR1A/MEF2A/XBP1/BMPR2/ACTG1/AKAP13/EPC1 36 GO:0060840 artery development 18/504 100/18722 1.62736340928899e-10 2.2431367251264e-08 MYLK/PDGFRB/TBX2/HAND2/MYOCD/EFEMP2/ADAMTS9/TGFB2/FKBP10/JAG1/MDK/SOX4/PLXND1/PKD2/CITED2/ZMIZ1/BMPR2/AKT3 18 GO:0006936 muscle contraction 33/504 347/18722 3.61591358029929e-10 4.82837460269339e-08 ACTA2/TPM2/MYL9/MYLK/MYH11/CRYAB/LMOD1/GJC1/EDNRA/HSPB6/FXYD1/TBX2/CNN1/PRKG1/MYOCD/FLNA/TPM1/CALD1/ARHGAP42/SULF2/SLMAP/PPP1R12B/SLC8A1/EDNRB/TPM4/MYL6/ATP2B4/CAV1/GSN/SMAD5/CALM2/ROCK2/NR4A1 33 GO:0150116 regulation of cell-substrate junction organization 15/504 71/18722 5.26041786183624e-10 6.81144409806856e-08 THBS1/THY1/APOD/DLC1/PEAK1/VCL/LIMS1/FERMT2/MAP4K4/ROCK2/PIK3R1/MACF1/PTEN/PTPRA/ACTG1 15 GO:0010631 epithelial cell migration 33/504 357/18722 7.52928249620377e-10 9.46253650184668e-08 DCN/SPARC/THBS1/SEMA5A/ADGRA2/ADAMTS9/KANK2/TGFB2/ZEB2/RRAS/NR2F2/FGFR1/MEF2C/ITGB1/FSTL1/TMSB4X/ETS1/ATP2B4/MYH9/RIN2/PLXND1/HDAC7/MAP4K4/HSPB1/RHOB/STARD13/ROCK2/ADAM9/MACF1/NR4A1/PTEN/BMPR2/AKT3 33 GO:0045785 positive regulation of cell adhesion 37/504 437/18722 8.15113812711266e-10 9.95137520490069e-08 EGFL6/NID1/IGFBP2/THY1/EDIL3/EFEMP2/EMILIN1/FLNA/LIMS2/FBLN2/TPM1/COL8A1/LGALS1/TGFB2/RRAS/CD81/MDK/MYADM/ETS1/IL6ST/SOX4/TJP1/CAV1/RIN2/LIMS1/B2M/IGF2/CITED2/FERMT2/JAK1/CCDC80/MAP4K4/MYO10/ZFHX3/ADAM9/XBP1/ZMIZ1 37 GO:0090132 epithelium migration 33/504 360/18722 9.32970935711218e-10 1.10738466897057e-07 DCN/SPARC/THBS1/SEMA5A/ADGRA2/ADAMTS9/KANK2/TGFB2/ZEB2/RRAS/NR2F2/FGFR1/MEF2C/ITGB1/FSTL1/TMSB4X/ETS1/ATP2B4/MYH9/RIN2/PLXND1/HDAC7/MAP4K4/HSPB1/RHOB/STARD13/ROCK2/ADAM9/MACF1/NR4A1/PTEN/BMPR2/AKT3 33 GO:1902903 regulation of supramolecular fiber organization 34/504 382/18722 1.11569223328033e-09 1.2548793885102e-07 SYNPO2/CRYAB/MAP1B/AEBP1/LMOD1/ELN/SEMA5A/EFEMP2/EMILIN1/PLEKHH2/FLNA/TPM1/DLC1/LPAR1/MYADM/SORBS3/TMSB4X/TJP1/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/CDC42EP3/FERMT2/NCKAP1/SVIL/ARL3/ROCK2/PIK3R1/TAOK1/ACTG1/AKAP13 34 GO:0061448 connective tissue development 27/504 252/18722 1.11597043677481e-09 1.2548793885102e-07 COL1A1/ACTA2/LUM/MGP/COL5A1/PDGFRB/HAND2/CTSK/COL27A1/TIMP1/BGN/SULF2/MAF/MEF2C/CRIP1/MDK/NFIB/EXT1/SOX6/EGR1/SERPINH1/BMP1/SMAD5/TGFBI/ARID5B/XBP1/BMPR2 27 GO:0001952 regulation of cell-matrix adhesion 19/504 128/18722 1.54244600978218e-09 1.68996712815365e-07 THBS1/THY1/APOD/EFEMP2/DLC1/PEAK1/JAG1/RRAS/VCL/RIN2/LIMS1/FERMT2/MAP4K4/ROCK2/PIK3R1/MACF1/PTEN/PTPRA/ACTG1 19 GO:0085029 extracellular matrix assembly 12/504 45/18722 1.63069315258897e-09 1.74198796025317e-07 COL1A2/MYH11/PXDN/ANTXR1/EFEMP2/EMILIN1/GAS6/FBLN5/FKBP10/LAMB2/LAMB1/QSOX1 12 GO:0001822 kidney development 29/504 293/18722 1.72469389483276e-09 1.79746756405375e-07 ACTA2/DCN/NID1/PDGFRB/AGTR1/PDGFRA/KANK2/TGFB2/SULF2/JAG1/GPC3/MEF2C/EXT1/SOX4/SPRY1/EGR1/PTK7/PLXND1/FBN1/LAMB2/PKD2/SMAD5/NOTCH2/ARID5B/ADAMTS1/PDGFA/WWTR1/ARL3/PBX1 29 GO:0051893 regulation of focal adhesion assembly 14/504 66/18722 1.88342654624555e-09 1.87160037955982e-07 THBS1/THY1/APOD/DLC1/PEAK1/VCL/LIMS1/FERMT2/MAP4K4/ROCK2/MACF1/PTEN/PTPRA/ACTG1 14 GO:0090109 regulation of cell-substrate junction assembly 14/504 66/18722 1.88342654624555e-09 1.87160037955982e-07 THBS1/THY1/APOD/DLC1/PEAK1/VCL/LIMS1/FERMT2/MAP4K4/ROCK2/MACF1/PTEN/PTPRA/ACTG1 14 GO:0050673 epithelial cell proliferation 36/504 437/18722 2.89728255768501e-09 2.81365644749729e-07 IGFBP5/SPARC/THBS1/IGFBP4/WFDC1/AGTR1/SEMA5A/WNT2/HGF/LIMS2/COL8A1/TGFB2/SULF2/NR2F2/GPC3/FGFR1/MEF2C/MDK/NFIB/EDNRB/LAMC1/CAV1/B2M/IGF2/CAV2/LAMB1/ZFP36L1/NOTCH2/HTRA1/ZFP36/XBP1/STAT3/NR4A1/PTEN/BMPR2/AKT3 36 GO:0051146 striated muscle cell differentiation 28/504 283/18722 3.33167847746969e-09 3.16361380760622e-07 IGFBP5/MYH11/PDGFRB/LMOD1/ADAMTS5/EHD2/MYOCD/PDGFRA/TPM1/SORBS2/PDLIM5/SGCB/MEF2C/CD81/ITGB1/SLC8A1/MYH9/SOX6/ADAM12/IGF2/CFL2/CSRP1/CAV2/PRKAR1A/MEF2A/XBP1/ACTG1/AKAP13 28 GO:0045765 regulation of angiogenesis 31/504 342/18722 3.98830326813121e-09 3.70478692711406e-07 DCN/SPARC/THBS1/SEMA5A/ADGRA2/HSPB6/ADAMTS9/EMILIN1/HGF/TGFB2/COL4A2/HSPG2/MTDH/RRAS/ITGB1/MDK/ETS1/TJP1/ATP2B4/ADAM12/PLXND1/HIPK2/JAK1/HSPB1/RHOB/ADAMTS1/ROCK2/XBP1/EPN2/STAT3/AKT3 31 GO:0071711 basement membrane organization 10/504 31/18722 4.88118286155739e-09 4.43772220583717e-07 NID1/PXDN/NID2/COL4A1/ITGB1/EXT1/CAV1/LAMB2/CAV2/LAMB1 10 GO:0010811 positive regulation of cell-substrate adhesion 18/504 123/18722 5.25615862067957e-09 4.67907620545079e-07 EGFL6/NID1/THY1/EDIL3/EFEMP2/EMILIN1/FLNA/LIMS2/FBLN2/COL8A1/RRAS/MDK/MYADM/RIN2/LIMS1/FERMT2/CCDC80/MAP4K4 18 GO:0048738 cardiac muscle tissue development 25/504 236/18722 5.86699636841484e-09 5.11626030249726e-07 MYH11/PDGFRB/GJC1/TBX2/MYOCD/ADAMTS9/PDGFRA/WNT2/MEIS1/TPM1/TGFB2/SORBS2/PDLIM5/SGCB/MEF2C/ITGB1/SLC8A1/SOX6/CITED2/SMAD5/NOTCH2/PRKAR1A/MEF2A/PTEN/AKAP13 25 GO:1901342 regulation of vasculature development 31/504 348/18722 6.03504042909182e-09 5.15754555070187e-07 DCN/SPARC/THBS1/SEMA5A/ADGRA2/HSPB6/ADAMTS9/EMILIN1/HGF/TGFB2/COL4A2/HSPG2/MTDH/RRAS/ITGB1/MDK/ETS1/TJP1/ATP2B4/ADAM12/PLXND1/HIPK2/JAK1/HSPB1/RHOB/ADAMTS1/ROCK2/XBP1/EPN2/STAT3/AKT3 31 GO:0051017 actin filament bundle assembly 20/504 157/18722 8.70282351683938e-09 7.29160095832444e-07 SYNPO2/PLS3/ELN/MYO1B/FLNA/TPM1/DLC1/CALD1/MARCKS/LPAR1/SORBS3/TJP1/EPS8/LIMA1/ACTN1/FERMT2/HSP90B1/ROCK2/PIK3R1/ACTG1 20 GO:0048041 focal adhesion assembly 15/504 87/18722 1.01925522546104e-08 8.26972500797974e-07 THBS1/THY1/APOD/DLC1/PEAK1/VCL/LIMS1/ACTN1/FERMT2/MAP4K4/ROCK2/MACF1/PTEN/PTPRA/ACTG1 15 GO:0043542 endothelial cell migration 27/504 279/18722 1.02573233190481e-08 8.26972500797974e-07 DCN/SPARC/THBS1/SEMA5A/ADGRA2/ADAMTS9/RRAS/NR2F2/FGFR1/MEF2C/ITGB1/FSTL1/TMSB4X/ETS1/ATP2B4/MYH9/RIN2/PLXND1/HDAC7/HSPB1/RHOB/STARD13/ROCK2/NR4A1/PTEN/BMPR2/AKT3 27 GO:0061572 actin filament bundle organization 20/504 161/18722 1.3463848389933e-08 1.05930361491465e-06 SYNPO2/PLS3/ELN/MYO1B/FLNA/TPM1/DLC1/CALD1/MARCKS/LPAR1/SORBS3/TJP1/EPS8/LIMA1/ACTN1/FERMT2/HSP90B1/ROCK2/PIK3R1/ACTG1 20 GO:0003007 heart morphogenesis 25/504 246/18722 1.3634846435831e-08 1.05930361491465e-06 COL5A1/SLIT3/ELN/TBX2/HAND2/WNT2/FLNA/TPM1/DLC1/TGFB2/JAG1/MEF2C/EXT1/SOX4/SPRY1/PLXND1/PKD2/CITED2/NOTCH2/ADAMTS1/PARVA/ZMIZ1/BMPR2/DHRS3/SOS1 25 GO:0050678 regulation of epithelial cell proliferation 32/504 381/18722 1.41721624423677e-08 1.08138660921852e-06 SPARC/THBS1/WFDC1/AGTR1/SEMA5A/WNT2/LIMS2/TGFB2/SULF2/NR2F2/GPC3/FGFR1/MEF2C/MDK/NFIB/EDNRB/LAMC1/CAV1/B2M/IGF2/CAV2/LAMB1/ZFP36L1/NOTCH2/HTRA1/ZFP36/XBP1/STAT3/NR4A1/PTEN/BMPR2/AKT3 32 GO:0001649 osteoblast differentiation 24/504 229/18722 1.46237678046347e-08 1.09626947068779e-06 COL1A1/COL6A1/IGFBP5/CTHRC1/DDR2/HAND2/HGF/VCAN/PDLIM7/TWSG1/JAG1/IFITM1/MEF2C/TPM4/IL6ST/IGF2/SMAD5/FERMT2/HDAC7/WWTR1/BCAP29/BMPR2/RRBP1/CRIM1 24 GO:0033002 muscle cell proliferation 25/504 248/18722 1.60492743531071e-08 1.18238878122115e-06 IGFBP5/THBS1/PDGFRB/OGN/ELN/APOD/TBX2/CNN1/PRKG1/MYOCD/EFEMP2/WNT2/MEIS1/TPM1/TGFB2/MMP2/IGFBP3/MEF2C/CITED2/PRKAR1A/ADAMTS1/JUN/STAT3/PTEN/BMPR2 25 GO:0034109 homotypic cell-cell adhesion 15/504 90/18722 1.64663551132577e-08 1.19255483727034e-06 MYL9/PRKG1/PDGFRA/FLNA/LGALS1/VCL/ACTB/IL6ST/MYH9/CSRP1/JAK1/HSPB1/TLN1/ACTG1/CD99 15 GO:0001654 eye development 31/504 371/18722 2.69752796300722e-08 1.91230475724275e-06 COL5A1/PDGFRB/CRYAB/THY1/LAMC3/TBX2/PDGFRA/WNT2/COL5A2/MEIS1/COL4A1/COL8A1/TGFB2/VIM/TWSG1/JAG1/MAF/ATP2B4/SPRY1/FBN1/LAMB2/CITED2/HIPK2/NOTCH2/FAT1/STAT3/MAN2A1/BMPR2/PBX1/TUG1/SOS1 31 GO:0007229 integrin-mediated signaling pathway 16/504 107/18722 2.72994594410971e-08 1.91230475724275e-06 COL3A1/ITGA1/THY1/FLNA/LIMS2/TIMP1/ITGB1/MYH9/DST/LIMS1/FERMT2/TLN1/ADAMTS1/ISG15/ADAM9/PTPRA 16 GO:0034446 substrate adhesion-dependent cell spreading 16/504 108/18722 3.12638266540204e-08 2.15468276278434e-06 LAMC3/ANTXR1/FLNA/LIMS2/AXL/PEAK1/MDK/LAMC1/MYADM/LIMS1/ACTN4/LAMB2/LAMB1/FERMT2/PARVA/PIK3R1 16 GO:0150063 visual system development 31/504 375/18722 3.45216511088302e-08 2.34144468552431e-06 COL5A1/PDGFRB/CRYAB/THY1/LAMC3/TBX2/PDGFRA/WNT2/COL5A2/MEIS1/COL4A1/COL8A1/TGFB2/VIM/TWSG1/JAG1/MAF/ATP2B4/SPRY1/FBN1/LAMB2/CITED2/HIPK2/NOTCH2/FAT1/STAT3/MAN2A1/BMPR2/PBX1/TUG1/SOS1 31 GO:0110053 regulation of actin filament organization 26/504 277/18722 3.60229257613756e-08 2.40509315278684e-06 SYNPO2/LMOD1/ELN/SEMA5A/PLEKHH2/FLNA/TPM1/DLC1/LPAR1/MYADM/SORBS3/TMSB4X/TJP1/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/CDC42EP3/FERMT2/NCKAP1/SVIL/ROCK2/PIK3R1/ACTG1 26 GO:0007265 Ras protein signal transduction 29/504 337/18722 4.02872129406506e-08 2.64841939839077e-06 COL1A2/COL3A1/PDGFRB/AGTR1/KANK2/DLC1/TGFB2/ARHGAP42/LPAR1/RAP2A/RRAS/RERG/ITGB1/EPS8/TIMP2/SPRY1/ARHGEF12/PSD3/CDC42EP3/NOTCH2/NCKAP1/MAP4K4/RHOB/STARD13/JUN/ROCK2/ARHGAP5/AKAP13/SOS1 29 GO:0034329 cell junction assembly 33/504 420/18722 4.21622832795424e-08 2.72968843111341e-06 THBS1/THY1/MAP1B/GJC1/CDH11/APOD/DLC1/PEAK1/FARP1/MTDH/PDLIM5/VCL/MEF2C/LAMC1/ACTB/TJP1/CAV1/DST/LIMS1/PLXND1/ACTN1/FERMT2/VMP1/HDAC7/MAP4K4/TLN1/ROCK2/MYO9A/MACF1/NPTN/PTEN/PTPRA/ACTG1 33 GO:0035051 cardiocyte differentiation 19/504 156/18722 4.28957575604972e-08 2.73572495605977e-06 MYH11/PDGFRB/TBX2/HAND2/MYOCD/PDGFRA/TGFB2/SORBS2/JAG1/PDLIM5/SGCB/MEF2C/ITGB1/SLC8A1/SPRY1/SOX6/CITED2/MEF2A/AKAP13 19 GO:0048880 sensory system development 31/504 381/18722 4.96211443083162e-08 3.11810514160934e-06 COL5A1/PDGFRB/CRYAB/THY1/LAMC3/TBX2/PDGFRA/WNT2/COL5A2/MEIS1/COL4A1/COL8A1/TGFB2/VIM/TWSG1/JAG1/MAF/ATP2B4/SPRY1/FBN1/LAMB2/CITED2/HIPK2/NOTCH2/FAT1/STAT3/MAN2A1/BMPR2/PBX1/TUG1/SOS1 31 GO:0090287 regulation of cellular response to growth factor stimulus 27/504 304/18722 6.22283753597088e-08 3.85364996973965e-06 DCN/THBS1/ADGRA2/TGFB1I1/MYOCD/EMILIN1/LTBP4/ZEB2/TWSG1/SULF2/GPC3/FGFR1/FSTL1/ATP2B4/CAV1/SPRY1/LTBP1/FBN1/CAV2/CITED2/HIPK2/NOTCH2/HTRA1/EPN2/NPTN/BMPR2/CRIM1 27 GO:0003205 cardiac chamber development 19/504 161/18722 7.15826748236482e-08 4.36961099316356e-06 SLIT3/TBX2/HAND2/MYOCD/WNT2/TPM1/TGFB2/JAG1/MEF2C/SOX4/PTK7/PLXND1/CITED2/NOTCH2/ADAMTS1/PARVA/BMPR2/DHRS3/SOS1 19 GO:0032835 glomerulus development 12/504 62/18722 8.08103773029564e-08 4.86341890444412e-06 ACTA2/NID1/PDGFRB/PDGFRA/SULF2/JAG1/MEF2C/EXT1/EGR1/LAMB2/NOTCH2/WWTR1 12 GO:0045667 regulation of osteoblast differentiation 17/504 132/18722 9.69308875291304e-08 5.70211299865098e-06 IGFBP5/CTHRC1/DDR2/HAND2/HGF/PDLIM7/TWSG1/JAG1/IFITM1/MEF2C/IL6ST/SMAD5/FERMT2/HDAC7/WWTR1/BMPR2/CRIM1 17 GO:0030239 myofibril assembly 12/504 63/18722 9.7414989211683e-08 5.70211299865098e-06 MYH11/PDGFRB/LMOD1/PDGFRA/TPM1/ITGB1/CFL2/CSRP1/PRKAR1A/MEF2A/ACTG1/AKAP13 12 GO:0010632 regulation of epithelial cell migration 26/504 292/18722 1.04051532136536e-07 6.00827292999216e-06 DCN/SPARC/THBS1/SEMA5A/ADGRA2/ADAMTS9/TGFB2/RRAS/NR2F2/FGFR1/MEF2C/TMSB4X/ETS1/ATP2B4/RIN2/HDAC7/MAP4K4/HSPB1/RHOB/STARD13/ROCK2/ADAM9/MACF1/PTEN/BMPR2/AKT3 26 GO:0022612 gland morphogenesis 16/504 118/18722 1.11688593161062e-07 6.31952414436119e-06 IGFBP5/TBX2/HGF/LIMS2/TGFB2/TWSG1/SULF2/CRIP1/MDK/NFIB/CAV1/PLXND1/NOTCH2/PDGFA/MSN/XBP1 16 GO:0048762 mesenchymal cell differentiation 23/504 236/18722 1.12399680545624e-07 6.31952414436119e-06 COL1A1/SEMA5A/EDNRA/TGFB1I1/HAND2/WNT2/HGF/FLNA/TGFB2/JAG1/FGFR1/MEF2C/MDK/EXT1/EDNRB/SPRY1/CITED2/FERMT2/DDX17/WWTR1/S100A4/ROCK2/PTEN 23 GO:0055002 striated muscle cell development 12/504 64/18722 1.17001667352555e-07 6.49283278698008e-06 MYH11/PDGFRB/LMOD1/PDGFRA/TPM1/ITGB1/CFL2/CSRP1/PRKAR1A/MEF2A/ACTG1/AKAP13 12 GO:0055001 muscle cell development 20/504 184/18722 1.28764418693454e-07 7.0539789881683e-06 MYH11/PDGFRB/LMOD1/EFEMP2/PDGFRA/TPM1/SORBS2/PDLIM5/SGCB/ITGB1/SLC8A1/ACTN4/CFL2/CSRP1/CAV2/ACTN1/PRKAR1A/MEF2A/ACTG1/AKAP13 20 GO:0002064 epithelial cell development 22/504 220/18722 1.35001718697547e-07 7.30205498727364e-06 ACTA2/COL18A1/FLNA/COL15A1/VIM/JAG1/VCL/PALLD/MYADM/IL6ST/TJP1/FNDC3A/LAMB2/NOTCH2/CLOCK/ROCK2/FAT1/MSN/ATRX/FOSL2/GSTM3/VEZF1 22 GO:0003206 cardiac chamber morphogenesis 16/504 121/18722 1.59310459787165e-07 8.50916993338195e-06 SLIT3/TBX2/HAND2/WNT2/TPM1/TGFB2/JAG1/MEF2C/SOX4/CITED2/NOTCH2/ADAMTS1/PARVA/BMPR2/DHRS3/SOS1 16 GO:0007266 Rho protein signal transduction 17/504 137/18722 1.67863942587021e-07 8.85534107005359e-06 COL1A2/COL3A1/PDGFRB/AGTR1/KANK2/DLC1/ARHGAP42/LPAR1/ITGB1/EPS8/ARHGEF12/CDC42EP3/RHOB/STARD13/ROCK2/ARHGAP5/AKAP13 17 GO:0003179 heart valve morphogenesis 11/504 55/18722 1.97921130164432e-07 1.01297182768348e-05 SLIT3/ELN/ADAMTS9/EMILIN1/TGFB2/JAG1/MEF2C/SOX4/NOTCH2/ROCK2/BMPR2 11 GO:0070527 platelet aggregation 12/504 67/18722 1.9854955610889e-07 1.01297182768348e-05 MYL9/PRKG1/PDGFRA/FLNA/VCL/ACTB/IL6ST/MYH9/CSRP1/HSPB1/TLN1/ACTG1 12 GO:0035909 aorta morphogenesis 9/504 34/18722 1.99133240171804e-07 1.01297182768348e-05 MYLK/PDGFRB/TBX2/EFEMP2/ADAMTS9/TGFB2/FKBP10/JAG1/SOX4 9 GO:0051216 cartilage development 20/504 190/18722 2.1823595313875e-07 1.09681828700372e-05 COL1A1/LUM/MGP/HAND2/CTSK/COL27A1/TIMP1/BGN/SULF2/MAF/MEF2C/MDK/NFIB/EXT1/SOX6/SERPINH1/BMP1/SMAD5/TGFBI/BMPR2 20 GO:0030336 negative regulation of cell migration 28/504 344/18722 2.20749760548374e-07 1.09681828700372e-05 COL3A1/DCN/IGFBP5/THBS1/THY1/APOD/PRKG1/MYOCD/ADAMTS9/EMILIN1/TPM1/TIMP1/DLC1/IGFBP3/JAG1/RAP2A/RRAS/NR2F2/VCL/IFITM1/MEF2C/ATP2B4/CNN2/CITED2/RHOB/STARD13/STAT3/PTEN 28 GO:0051271 negative regulation of cellular component movement 29/504 367/18722 2.50589104192574e-07 1.23076694507456e-05 COL3A1/DCN/IGFBP5/THBS1/THY1/APOD/PRKG1/MYOCD/ADAMTS9/EMILIN1/TPM1/TIMP1/DLC1/IGFBP3/JAG1/RAP2A/RRAS/NR2F2/VCL/IFITM1/MEF2C/ATP2B4/CNN2/ACTN1/CITED2/RHOB/STARD13/STAT3/PTEN 29 GO:0006939 smooth muscle contraction 15/504 110/18722 2.5805494539717e-07 1.25303270645694e-05 ACTA2/MYLK/MYH11/EDNRA/TBX2/CNN1/PRKG1/MYOCD/ARHGAP42/SULF2/SLC8A1/EDNRB/ATP2B4/CAV1/ROCK2 15 GO:0048771 tissue remodeling 19/504 175/18722 2.70162143752579e-07 1.29708184298289e-05 IGFBP5/CTHRC1/DDR2/HAND2/CTSK/FLNA/AXL/TIMP1/MMP2/BGN/JAG1/MEF2C/MDK/EXT1/CAV1/P3H4/NOTCH2/ROCK2/BMPR2 19 GO:0045669 positive regulation of osteoblast differentiation 12/504 69/18722 2.77942949811418e-07 1.31961136060465e-05 CTHRC1/DDR2/HGF/PDLIM7/JAG1/IFITM1/MEF2C/IL6ST/SMAD5/FERMT2/WWTR1/BMPR2 12 GO:0035904 aorta development 11/504 58/18722 3.50155341436174e-07 1.64419096039205e-05 MYLK/PDGFRB/TBX2/EFEMP2/ADAMTS9/TGFB2/FKBP10/JAG1/SOX4/PLXND1/PKD2 11 GO:2000146 negative regulation of cell motility 28/504 359/18722 5.26306919959932e-07 2.44446681411825e-05 COL3A1/DCN/IGFBP5/THBS1/THY1/APOD/PRKG1/MYOCD/ADAMTS9/EMILIN1/TPM1/TIMP1/DLC1/IGFBP3/JAG1/RAP2A/RRAS/NR2F2/VCL/IFITM1/MEF2C/ATP2B4/CNN2/CITED2/RHOB/STARD13/STAT3/PTEN 28 GO:0043010 camera-type eye development 26/504 322/18722 6.98205281525303e-07 3.20799050318024e-05 PDGFRB/CRYAB/THY1/LAMC3/TBX2/PDGFRA/WNT2/MEIS1/COL4A1/COL8A1/TGFB2/VIM/TWSG1/JAG1/MAF/ATP2B4/SPRY1/FBN1/LAMB2/CITED2/HIPK2/NOTCH2/FAT1/MAN2A1/BMPR2/SOS1 26 GO:0048662 negative regulation of smooth muscle cell proliferation 12/504 75/18722 7.11501111514566e-07 3.23430239308696e-05 IGFBP5/OGN/APOD/CNN1/PRKG1/MYOCD/EFEMP2/TPM1/IGFBP3/MEF2C/PTEN/BMPR2 12 GO:0003158 endothelium development 16/504 136/18722 8.03587452068241e-07 3.6144517712501e-05 COL18A1/COL15A1/ZEB1/JAG1/NR2F2/VCL/FSTL1/MYADM/TJP1/RHOB/STARD13/ROCK2/MSN/BMPR2/GSTM3/VEZF1 16 GO:0040013 negative regulation of locomotion 29/504 391/18722 9.27788623894022e-07 4.12962582281162e-05 COL3A1/DCN/IGFBP5/THBS1/THY1/SEMA5A/APOD/PRKG1/MYOCD/ADAMTS9/EMILIN1/TPM1/TIMP1/DLC1/IGFBP3/JAG1/RAP2A/RRAS/NR2F2/VCL/IFITM1/MEF2C/ATP2B4/CNN2/CITED2/RHOB/STARD13/STAT3/PTEN 29 GO:0048732 gland development 31/504 436/18722 9.65341913282709e-07 4.25248040768764e-05 IGFBP5/TBX2/HAND2/PDGFRA/WNT2/HGF/LIMS2/TGFB2/TWSG1/SULF2/CRIP1/MDK/NFIB/EXT1/ETS1/CAV1/PLXND1/IGF2/TSPO/PKD2/CITED2/NOTCH2/ARID5B/NCOR2/PDGFA/MSN/XBP1/ARHGAP5/PTEN/MAN2A1/PBX1 31 GO:0031532 actin cytoskeleton reorganization 14/504 107/18722 1.07862699782646e-06 4.70303383848211e-05 ANTXR1/PDGFRA/FLNA/RAP2A/MDK/TJP1/MYH9/EPS8/PTK7/CDC42BPA/GSN/NOTCH2/PARVA/MKLN1 14 GO:0030168 platelet activation 15/504 123/18722 1.11706186620086e-06 4.82141954977401e-05 COL3A1/MYL9/PRKG1/PDGFRA/FLNA/AXL/VCL/ACTB/IL6ST/MYH9/CSRP1/HSPB1/TLN1/PDGFA/ACTG1 15 GO:0003170 heart valve development 11/504 65/18722 1.16136241512831e-06 4.96250159984326e-05 SLIT3/ELN/ADAMTS9/EMILIN1/TGFB2/JAG1/MEF2C/SOX4/NOTCH2/ROCK2/BMPR2 11 GO:0010634 positive regulation of epithelial cell migration 18/504 176/18722 1.34128599880729e-06 5.64949296633975e-05 SPARC/THBS1/SEMA5A/ADGRA2/TGFB2/RRAS/FGFR1/TMSB4X/ETS1/RIN2/HDAC7/MAP4K4/HSPB1/RHOB/ROCK2/ADAM9/BMPR2/AKT3 18 GO:0010594 regulation of endothelial cell migration 21/504 232/18722 1.34858011365938e-06 5.64949296633975e-05 DCN/SPARC/THBS1/SEMA5A/ADGRA2/ADAMTS9/RRAS/NR2F2/FGFR1/MEF2C/TMSB4X/ETS1/ATP2B4/RIN2/HDAC7/HSPB1/RHOB/STARD13/ROCK2/BMPR2/AKT3 21 GO:0030834 regulation of actin filament depolymerization 10/504 54/18722 1.51090182729726e-06 6.26804224081669e-05 LMOD1/SEMA5A/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/SVIL 10 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 22/504 256/18722 1.80801467442508e-06 7.39402052002813e-05 THBS1/TGFB1I1/MYOCD/EMILIN1/LTBP4/TGFB2/ZEB2/TWSG1/GPC3/FSTL1/CAV1/SPRY1/LTBP1/FBN1/CAV2/CITED2/HIPK2/NOTCH2/HTRA1/RBPMS/BMPR2/CRIM1 22 GO:0007596 blood coagulation 20/504 217/18722 1.81692523894911e-06 7.39402052002813e-05 COL3A1/MYL9/THBS1/PRKG1/PDGFRA/FLNA/GAS6/AXL/TFPI/VCL/ACTB/IL6ST/SERPING1/MYH9/CAV1/CSRP1/HSPB1/TLN1/PDGFA/ACTG1 20 GO:0048660 regulation of smooth muscle cell proliferation 18/504 180/18722 1.85838670901793e-06 7.49140227135248e-05 IGFBP5/THBS1/PDGFRB/OGN/ELN/APOD/CNN1/PRKG1/MYOCD/EFEMP2/TPM1/MMP2/IGFBP3/MEF2C/ADAMTS1/JUN/PTEN/BMPR2 18 GO:0045766 positive regulation of angiogenesis 18/504 181/18722 2.01310801002015e-06 7.96482456186674e-05 THBS1/SEMA5A/HSPB6/HGF/MTDH/RRAS/ITGB1/MDK/ETS1/TJP1/ADAM12/HIPK2/JAK1/HSPB1/RHOB/XBP1/STAT3/AKT3 18 GO:1904018 positive regulation of vasculature development 18/504 181/18722 2.01310801002015e-06 7.96482456186674e-05 THBS1/SEMA5A/HSPB6/HGF/MTDH/RRAS/ITGB1/MDK/ETS1/TJP1/ADAM12/HIPK2/JAK1/HSPB1/RHOB/XBP1/STAT3/AKT3 18 GO:0048659 smooth muscle cell proliferation 18/504 184/18722 2.54973648858659e-06 9.86009743163656e-05 IGFBP5/THBS1/PDGFRB/OGN/ELN/APOD/CNN1/PRKG1/MYOCD/EFEMP2/TPM1/MMP2/IGFBP3/MEF2C/ADAMTS1/JUN/PTEN/BMPR2 18 GO:0000302 response to reactive oxygen species 20/504 222/18722 2.58443929872056e-06 9.86009743163656e-05 COL1A1/PDGFRB/CRYAB/APOD/PDGFRA/HGF/AXL/TPM1/FBLN5/TXNIP/FOXO1/MMP2/SLC8A1/ETS1/PKD2/RHOB/MAP1LC3A/JUN/ADAM9/SOD3 20 GO:0007599 hemostasis 20/504 222/18722 2.58443929872056e-06 9.86009743163656e-05 COL3A1/MYL9/THBS1/PRKG1/PDGFRA/FLNA/GAS6/AXL/TFPI/VCL/ACTB/IL6ST/SERPING1/MYH9/CAV1/CSRP1/HSPB1/TLN1/PDGFA/ACTG1 20 GO:0050817 coagulation 20/504 222/18722 2.58443929872056e-06 9.86009743163656e-05 COL3A1/MYL9/THBS1/PRKG1/PDGFRA/FLNA/GAS6/AXL/TFPI/VCL/ACTB/IL6ST/SERPING1/MYH9/CAV1/CSRP1/HSPB1/TLN1/PDGFA/ACTG1 20 GO:1901888 regulation of cell junction assembly 19/504 204/18722 2.81077207350836e-06 0.00010628698292125 THBS1/THY1/APOD/DLC1/PEAK1/FARP1/PDLIM5/VCL/MEF2C/TJP1/CAV1/LIMS1/FERMT2/MAP4K4/ROCK2/MACF1/PTEN/PTPRA/ACTG1 19 GO:0010595 positive regulation of endothelial cell migration 15/504 133/18722 3.02352699452329e-06 0.000113329217961386 SPARC/THBS1/SEMA5A/ADGRA2/RRAS/FGFR1/TMSB4X/ETS1/RIN2/HDAC7/HSPB1/RHOB/ROCK2/BMPR2/AKT3 15 GO:0048592 eye morphogenesis 16/504 151/18722 3.25302870068164e-06 0.000120871231634892 COL5A1/THY1/TBX2/WNT2/COL5A2/MEIS1/COL8A1/JAG1/FBN1/CITED2/HIPK2/NOTCH2/FAT1/STAT3/MAN2A1/TUG1 16 GO:0030042 actin filament depolymerization 10/504 59/18722 3.51651410105428e-06 0.000128993165411982 LMOD1/SEMA5A/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/SVIL 10 GO:0045446 endothelial cell differentiation 14/504 118/18722 3.53199165766485e-06 0.000128993165411982 COL18A1/COL15A1/ZEB1/JAG1/NR2F2/VCL/FSTL1/MYADM/TJP1/ROCK2/MSN/BMPR2/GSTM3/VEZF1 14 GO:1901879 regulation of protein depolymerization 12/504 87/18722 3.60564522981228e-06 0.000130567136160914 MAP1B/LMOD1/SEMA5A/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/SVIL/TAOK1 12 GO:0022604 regulation of cell morphogenesis 24/504 309/18722 3.67781071833523e-06 0.000132061220163415 SPARC/FLNA/LIMS2/TPM1/DLC1/LPAR1/MDK/MYADM/MYH9/EPS8/RHOQ/LIMS1/ACTN4/PLXND1/CDC42EP3/FERMT2/RHOB/MYO10/RND3/PARVA/MKLN1/MSN/MYO9A/MACF1 24 GO:0003151 outflow tract morphogenesis 11/504 74/18722 4.36019032941744e-06 0.000155259110646673 ELN/TBX2/HAND2/TGFB2/JAG1/MEF2C/PLXND1/CITED2/PARVA/BMPR2/DHRS3 11 GO:0007519 skeletal muscle tissue development 16/504 155/18722 4.57793984014599e-06 0.000161665594520197 DCN/ELN/MYOCD/NR2F2/MEF2C/MYL6/CAV1/EGR1/IGF2/CFL2/CAV2/CITED2/SVIL/DDX17/ATF3/NR4A1 16 GO:0090257 regulation of muscle system process 21/504 252/18722 5.02507607602091e-06 0.000176001230105224 IGFBP5/MYL9/HSPB6/CNN1/HAND2/PRKG1/MYOCD/TPM1/ARHGAP42/FOXO1/LMCD1/PPP1R12B/SLC8A1/IL6ST/ATP2B4/CAV1/CALM2/ROCK2/MEF2A/FBXO32/NR4A1 21 GO:0071900 regulation of protein serine/threonine kinase activity 26/504 359/18722 5.23322795523282e-06 0.000181801488233413 THBS1/PDGFRB/THY1/MYOCD/CCND2/NR2F2/FGFR1/SLC8A1/PKIG/ACTB/ATP2B4/CAV1/SPRY1/IGF2/PKD2/FERMT2/CALM2/PRKAR1A/PDGFA/AIDA/ADAM9/PTEN/BMPR2/TAOK1/CCNG2/AKAP13 26 GO:0001837 epithelial to mesenchymal transition 16/504 157/18722 5.40662707791292e-06 0.000186310625031628 COL1A1/TGFB1I1/WNT2/HGF/FLNA/TGFB2/JAG1/FGFR1/MDK/SPRY1/FERMT2/DDX17/WWTR1/S100A4/ROCK2/PTEN 16 GO:0048545 response to steroid hormone 25/504 339/18722 5.78953956098415e-06 0.000197909620352682 COL1A1/IGFBP7/SPARC/THBS1/IGFBP2/SLIT3/PLPP1/KANK2/TFPI/TGFB2/TXNIP/FOXO1/MDK/CAV1/NR3C1/TSPO/ZFP36L1/NCOR2/ZFP36/DDX17/CLOCK/ADAM9/FBXO32/RBFOX2/ZMIZ1 25 GO:0010927 cellular component assembly involved in morphogenesis 13/504 107/18722 6.02901191064676e-06 0.00020446006265233 MYH11/PDGFRB/LMOD1/PMP22/PDGFRA/TPM1/ITGB1/CFL2/CSRP1/PRKAR1A/MEF2A/ACTG1/AKAP13 13 GO:0030324 lung development 17/504 177/18722 6.18628846356873e-06 0.000208141815786056 IGFBP5/SPARC/PDGFRB/ADAMTS2/MYOCD/PDGFRA/WNT2/CRISPLD2/GPC3/NFIB/EXT1/SPRY1/PTK7/EIF4EBP1/PDGFA/MAN2A1/BMPR2 17 GO:0007492 endoderm development 11/504 77/18722 6.48153265851316e-06 0.000216371789451771 COL6A1/COL5A1/COL12A1/COL5A2/COL8A1/COL4A2/MMP2/EXT1/LAMC1/LAMB1/ZFP36L1 11 GO:0072006 nephron development 15/504 142/18722 6.82797450874557e-06 0.000226170039347828 ACTA2/NID1/PDGFRB/PDGFRA/SULF2/JAG1/GPC3/MEF2C/EXT1/EGR1/LAMB2/PKD2/NOTCH2/WWTR1/PBX1 15 GO:0030323 respiratory tube development 17/504 181/18722 8.34383181951498e-06 0.000274255333575289 IGFBP5/SPARC/PDGFRB/ADAMTS2/MYOCD/PDGFRA/WNT2/CRISPLD2/GPC3/NFIB/EXT1/SPRY1/PTK7/EIF4EBP1/PDGFA/MAN2A1/BMPR2 17 GO:0090288 negative regulation of cellular response to growth factor stimulus 13/504 111/18722 9.06513148252474e-06 0.000295689365075025 DCN/THBS1/ADGRA2/EMILIN1/TWSG1/SULF2/ATP2B4/SPRY1/FBN1/HIPK2/HTRA1/EPN2/CRIM1 13 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 14/504 128/18722 9.21201493399621e-06 0.000298204089492165 THBS1/TGFB1I1/MYOCD/EMILIN1/LTBP4/ZEB2/CAV1/SPRY1/LTBP1/FBN1/CAV2/CITED2/HIPK2/HTRA1 14 GO:0060538 skeletal muscle organ development 16/504 166/18722 1.10446251068926e-05 0.000352191664789196 DCN/ELN/MYOCD/NR2F2/MEF2C/MYL6/CAV1/EGR1/IGF2/CFL2/CAV2/CITED2/SVIL/DDX17/ATF3/NR4A1 16 GO:1902904 negative regulation of supramolecular fiber organization 16/504 166/18722 1.10446251068926e-05 0.000352191664789196 CRYAB/MAP1B/LMOD1/EMILIN1/PLEKHH2/DLC1/MYADM/TMSB4X/TJP1/EPS8/SPTBN1/LIMA1/GSN/SVIL/PIK3R1/TAOK1 16 GO:1905314 semi-lunar valve development 8/504 41/18722 1.14035547757961e-05 0.000360943626347976 SLIT3/ELN/EMILIN1/TGFB2/JAG1/NOTCH2/ROCK2/BMPR2 8 GO:1903034 regulation of response to wounding 16/504 167/18722 1.19176187584947e-05 0.00037444106584594 THBS1/MYLK/WFDC1/PRKG1/PDGFRA/FLNA/TFPI/ITGB1/MDK/SERPING1/CAV1/FERMT2/PDGFA/XBP1/PTEN/ACTG1 16 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 14/504 131/18722 1.2047199827012e-05 0.00037574952453155 THBS1/TGFB1I1/MYOCD/EMILIN1/LTBP4/ZEB2/CAV1/SPRY1/LTBP1/FBN1/CAV2/CITED2/HIPK2/HTRA1 14 GO:0006979 response to oxidative stress 29/504 446/18722 1.22105829896419e-05 0.000378085660251738 COL1A1/PXDN/PDGFRB/CRYAB/APOD/MSRB3/PDGFRA/HGF/AXL/TPM1/FBLN5/TXNIP/FOXO1/MMP2/MGST1/SLC8A1/ETS1/PKD2/HSPB1/RHOB/RBPMS/MAP1LC3A/JUN/ADAM9/GPX8/NCOA7/NFE2L1/SLC25A24/SOD3 29 GO:0010812 negative regulation of cell-substrate adhesion 10/504 68/18722 1.31047691272025e-05 0.000399976274860972 COL1A1/THBS1/APOD/LGALS1/DLC1/JAG1/ACTN4/MAP4K4/PIK3R1/PTEN 10 GO:0060411 cardiac septum morphogenesis 10/504 68/18722 1.31047691272025e-05 0.000399976274860972 SLIT3/TBX2/TGFB2/JAG1/SOX4/CITED2/NOTCH2/PARVA/BMPR2/DHRS3 10 GO:0150105 protein localization to cell-cell junction 6/504 21/18722 1.42082251245193e-05 0.000430579758560787 FLNA/VCL/ACTB/TJP1/JAK1/ACTG1 6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 5/504 13/18722 1.49165390462626e-05 0.000448861770032957 THBS1/TIMP3/ATF3/PTEN/PEA15 5 GO:0061041 regulation of wound healing 14/504 134/18722 1.56273693282582e-05 0.000466963280696834 THBS1/MYLK/WFDC1/PRKG1/PDGFRA/TFPI/ITGB1/SERPING1/CAV1/FERMT2/PDGFA/XBP1/PTEN/ACTG1 14 GO:0048008 platelet-derived growth factor receptor signaling pathway 9/504 56/18722 1.6997912535862e-05 0.000504389446289849 PDGFRB/APOD/MYOCD/PDGFRA/TXNIP/HIP1/ARID5B/PDGFA/PTEN 9 GO:0008360 regulation of cell shape 15/504 154/18722 1.82590140389504e-05 0.000538074255092657 TPM1/DLC1/LPAR1/MYH9/EPS8/RHOQ/PLXND1/CDC42EP3/FERMT2/RHOB/MYO10/RND3/PARVA/MKLN1/MSN 15 GO:0003279 cardiac septum development 12/504 103/18722 2.10635843533022e-05 0.000616470520148358 SLIT3/TBX2/TGFB2/JAG1/SOX4/PTK7/PLXND1/CITED2/NOTCH2/PARVA/BMPR2/DHRS3 12 GO:0032963 collagen metabolic process 12/504 104/18722 2.32395202104022e-05 0.000675527005843869 COL1A2/COL1A1/COL5A1/PDGFRB/ADAMTS2/EMILIN1/CTSK/VIM/MMP2/ITGB1/SERPINH1/P3H4 12 GO:0035987 endodermal cell differentiation 8/504 45/18722 2.34074179541095e-05 0.000675810114310203 COL6A1/COL5A1/COL12A1/COL5A2/COL8A1/COL4A2/MMP2/LAMB1 8 GO:0051056 regulation of small GTPase mediated signal transduction 22/504 302/18722 2.52418235336318e-05 0.00071922866153381 COL3A1/PDGFRB/CHN1/KANK2/DLC1/TGFB2/ARHGAP42/LPAR1/ITGB1/EPS8/TIMP2/SPRY1/ARHGEF12/PSD3/NOTCH2/MAP4K4/STARD13/ITSN1/ARHGAP5/MYO9A/AKAP13/SOS1 22 GO:0030325 adrenal gland development 6/504 23/18722 2.52479052726589e-05 0.00071922866153381 PDGFRA/MDK/TSPO/CITED2/ARID5B/PBX1 6 GO:0070482 response to oxygen levels 24/504 347/18722 2.55877667272672e-05 0.000724082961759025 COL1A1/THBS1/PDGFRB/CRYAB/COX4I2/EDNRA/MYOCD/TGFB2/FOXO1/MMP2/SLC8A1/ETS1/MALAT1/CAV1/EGR1/CITED2/HIPK2/ZFP36L1/EIF4EBP1/HSP90B1/ROCK2/PTEN/PLOD2/SOD3 24 GO:0035265 organ growth 16/504 178/18722 2.64436804928109e-05 0.000743380570695929 PDGFRB/TBX2/DDR2/WNT2/COL27A1/MEIS1/TGFB2/SORBS2/PDLIM5/MEF2C/EXT1/IGF2/CITED2/PRKAR1A/PTEN/AKAP13 16 GO:0007163 establishment or maintenance of cell polarity 18/504 218/18722 2.66970775338443e-05 0.000745598773216448 MAP1B/ITGB1/ACTB/MYH9/SPRY1/PTK7/DST/GSN/RHOB/MAP4/RND3/PARVA/ROCK2/FAT1/MSN/AMOTL2/MYO9A/RAB11FIP2 18 GO:0001936 regulation of endothelial cell proliferation 16/504 179/18722 2.83333300427461e-05 0.000786157917354898 SPARC/THBS1/AGTR1/SEMA5A/WNT2/NR2F2/FGFR1/MEF2C/MDK/CAV1/IGF2/CAV2/STAT3/NR4A1/BMPR2/AKT3 16 GO:0061564 axon development 29/504 467/18722 2.86463192109111e-05 0.000789714335407892 THY1/MAP1B/LAMA2/SLIT3/CDH11/SEMA5A/APOD/CHN1/FLNA/NEXN/METRN/NOTCH3/VCL/ITGB1/PALLD/NFIB/EXT1/ACTB/ENAH/PLXND1/LAMB2/TSPO/NOTCH2/DPYSL2/MACF1/NPTN/PTEN/BMPR2/SOS1 29 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 11/504 90/18722 2.94701387329939e-05 0.000807217325680019 IGFBP5/CNN1/PRKG1/MYOCD/EFEMP2/TPM1/MMP2/MEF2C/ADAMTS1/JUN/PTEN 11 GO:0031102 neuron projection regeneration 9/504 60/18722 3.01524907704166e-05 0.000820647089566817 THY1/MAP1B/APOD/HGF/FLNA/LAMB2/TSPO/MAP4K4/PTEN 9 GO:0045216 cell-cell junction organization 17/504 200/18722 3.0731482786712e-05 0.000831111556630509 GJC1/CDH11/FLNA/LIMS2/TGFB2/MTDH/VCL/EXT1/ACTB/TJP1/CAV1/LIMS1/FERMT2/HDAC7/TLN1/ROCK2/ACTG1 17 GO:0043588 skin development 20/504 263/18722 3.19039372243029e-05 0.000857393231191486 COL1A2/COL3A1/COL1A1/IGFBP5/COL5A1/COL5A3/ADAMTS2/COL5A2/TGFB2/TXNIP/JAG1/PALLD/EXT1/ZFP36L1/ZFP36/PDGFA/ROCK2/ADAM9/FOSL2/SOS1 20 GO:0055006 cardiac cell development 11/504 91/18722 3.27222239139767e-05 0.000866268386138794 MYH11/PDGFRB/PDGFRA/SORBS2/JAG1/PDLIM5/SGCB/SLC8A1/SPRY1/MEF2A/AKAP13 11 GO:1990874 vascular associated smooth muscle cell proliferation 11/504 91/18722 3.27222239139767e-05 0.000866268386138794 IGFBP5/CNN1/PRKG1/MYOCD/EFEMP2/TPM1/MMP2/MEF2C/ADAMTS1/JUN/PTEN 11 GO:0055007 cardiac muscle cell differentiation 13/504 125/18722 3.28423773822805e-05 0.000866268386138794 MYH11/PDGFRB/MYOCD/PDGFRA/SORBS2/PDLIM5/SGCB/MEF2C/ITGB1/SLC8A1/SOX6/MEF2A/AKAP13 13 GO:0010763 positive regulation of fibroblast migration 5/504 15/18722 3.32838182611589e-05 0.000872526106932097 THBS1/AKAP12/DDR2/ITGB1/SLC8A1 5 GO:0035633 maintenance of blood-brain barrier 7/504 35/18722 3.43534419218027e-05 0.000895074739828434 LAMA2/VCL/ITGB1/LAMC1/ACTB/TJP1/ACTG1 7 GO:0060541 respiratory system development 17/504 203/18722 3.71529025456354e-05 0.000962147591378788 IGFBP5/SPARC/PDGFRB/ADAMTS2/MYOCD/PDGFRA/WNT2/CRISPLD2/GPC3/NFIB/EXT1/SPRY1/PTK7/EIF4EBP1/PDGFA/MAN2A1/BMPR2 17 GO:0048146 positive regulation of fibroblast proliferation 8/504 48/18722 3.81778514834956e-05 0.00098241263963108 PDGFRB/DDR2/PDGFRA/WNT2/GAS6/PDGFA/FOSL2/ZMIZ1 8 GO:1990778 protein localization to cell periphery 23/504 333/18722 3.83952517712123e-05 0.00098241263963108 EHD2/FLNA/GAS6/RAMP1/SLMAP/RAP2A/EPB41L2/CD81/ITGB1/MYADM/ACTB/ATP2B4/CAV1/SPTBN1/RHOQ/FAM126A/SEC23A/PREPL/ARL3/ROCK2/PIK3R1/MACF1/RAB11FIP2 23 GO:0007369 gastrulation 16/504 185/18722 4.23930557573884e-05 0.00107824718601976 COL6A1/COL5A1/COL12A1/COL5A2/COL8A1/COL4A2/MMP2/TWSG1/GPC3/ITGB1/EXT1/UGDH/MYADM/LAMB1/PRKAR1A/BMPR2 16 GO:0062197 cellular response to chemical stress 23/504 337/18722 4.61799342761019e-05 0.00116761455125316 MYLK/PDGFRA/HGF/AXL/TPM1/FBLN5/FOXO1/MMP2/MGST1/ETS1/CAV1/TSPO/PKD2/ZFP36L1/HSPB1/RHOB/MAP1LC3A/JUN/GPX8/NCOA7/NFE2L1/SLC25A24/SOD3 23 GO:0051014 actin filament severing 5/504 16/18722 4.73438877575929e-05 0.00119000254345997 MYH9/GSN/DSTN/CFL2/SVIL 5 GO:0045926 negative regulation of growth 19/504 249/18722 4.77648413460999e-05 0.00119356238053734 IGFBP5/MEG3/CRYAB/WFDC1/SLIT3/SEMA5A/FHL1/ENPP1/MEIS1/MT1E/TGFB2/GPC3/RERG/CITED2/NOTCH2/CCDC85B/PTEN/BMPR2/DCBLD2 19 GO:0007568 aging 23/504 339/18722 5.0579763978514e-05 0.00125190460402035 DCN/IGFBP5/IGFBP2/PDGFRB/CRYAB/PRELP/APOD/TBX2/TIMP1/COL4A2/EDNRB/SERPING1/TIMP2/LIMS1/B2M/TSPO/CITED2/JUN/SMC6/STAT3/PTEN/ZMIZ1/AKT3 23 GO:0016049 cell growth 29/504 482/18722 5.06855830787551e-05 0.00125190460402035 IGFBP7/IGFBP5/MEG3/IGFBP4/CRYAB/MAP1B/WFDC1/SLIT3/AGTR1/SEMA5A/MYOCD/FHL1/ENPP1/LTBP4/FBLN5/TGFB2/SORBS2/PDLIM5/VCL/RERG/ITGB1/EXT1/LAMB2/CCDC85B/DPYSL2/MACF1/BMPR2/AKAP13/DCBLD2 29 GO:0001885 endothelial cell development 9/504 64/18722 5.10706112781331e-05 0.00125416506891645 COL18A1/COL15A1/VCL/MYADM/TJP1/ROCK2/MSN/GSTM3/VEZF1 9 GO:1902905 positive regulation of supramolecular fiber organization 17/504 209/18722 5.36580383841757e-05 0.00131017598866047 SYNPO2/MAP1B/LMOD1/SEMA5A/EFEMP2/FLNA/TPM1/LPAR1/SORBS3/GSN/DSTN/CFL2/CDC42EP3/FERMT2/NCKAP1/ARL3/ROCK2 17 GO:0055017 cardiac muscle tissue growth 11/504 96/18722 5.40426169253166e-05 0.00131206876205612 TBX2/WNT2/MEIS1/TGFB2/SORBS2/PDLIM5/MEF2C/CITED2/PRKAR1A/PTEN/AKAP13 11 GO:0046578 regulation of Ras protein signal transduction 16/504 189/18722 5.48939104623215e-05 0.00132520722827966 COL3A1/PDGFRB/KANK2/DLC1/TGFB2/ARHGAP42/LPAR1/ITGB1/EPS8/TIMP2/SPRY1/PSD3/NOTCH2/MAP4K4/STARD13/AKAP13 16 GO:0001570 vasculogenesis 10/504 80/18722 5.56340838788897e-05 0.00133553056412638 PDGFRB/GJC1/MYOCD/RRAS/CAV1/RIN2/CITED2/ZFP36L1/HDAC7/ZMIZ1 10 GO:0051261 protein depolymerization 12/504 114/18722 5.82503175440759e-05 0.00138279781592131 MAP1B/LMOD1/SEMA5A/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/SVIL/TAOK1 12 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 12/504 114/18722 5.82503175440759e-05 0.00138279781592131 THBS1/TGFB1I1/MYOCD/TGFB2/ZEB2/TWSG1/GPC3/CITED2/HIPK2/NOTCH2/RBPMS/BMPR2 12 GO:0014909 smooth muscle cell migration 11/504 97/18722 5.95018675262503e-05 0.00140470430905894 IGFBP5/PDGFRB/PRKG1/MYOCD/TPM1/IGFBP3/MEF2C/MDK/ADAMTS1/PDGFA/PARVA 11 GO:0043434 response to peptide hormone 26/504 414/18722 6.12973191745465e-05 0.00143913980677383 COL1A1/IGFBP5/SPARC/MAP1B/AGTR1/RARRES2/ENPP1/TIMP1/FOXO1/EDNRB/CAV1/RHOQ/EGR1/IGF2/FBN1/CAV2/ZFP36L1/ROCK2/XBP1/STAT3/PIK3R1/NR4A1/PTEN/PTPRA/EIF4EBP2/STAT2 26 GO:0061437 renal system vasculature development 6/504 27/18722 6.75622709005882e-05 0.0015689868671642 ACTA2/PDGFRB/PDGFRA/EGR1/PKD2/NOTCH2 6 GO:0061440 kidney vasculature development 6/504 27/18722 6.75622709005882e-05 0.0015689868671642 ACTA2/PDGFRB/PDGFRA/EGR1/PKD2/NOTCH2 6 GO:0060395 SMAD protein signal transduction 10/504 82/18722 6.89011709376158e-05 0.00159143082927801 TGFB2/VIM/SPTBN1/HIPK2/SMAD5/RBPMS/JUN/WWTR1/ZMIZ1/BMPR2 10 GO:0090596 sensory organ morphogenesis 19/504 256/18722 6.93841131520751e-05 0.00159396943816568 COL5A1/THY1/CTHRC1/TBX2/WNT2/COL5A2/MEIS1/COL8A1/JAG1/TSHZ1/PTK7/FBN1/CITED2/HIPK2/NOTCH2/FAT1/STAT3/MAN2A1/TUG1 19 GO:0001935 endothelial cell proliferation 16/504 193/18722 7.05322234855194e-05 0.0016116801655274 SPARC/THBS1/AGTR1/SEMA5A/WNT2/NR2F2/FGFR1/MEF2C/MDK/CAV1/IGF2/CAV2/STAT3/NR4A1/BMPR2/AKT3 16 GO:0007409 axonogenesis 26/504 418/18722 7.18021750880476e-05 0.00163197177740015 THY1/MAP1B/LAMA2/SLIT3/CDH11/SEMA5A/CHN1/NEXN/METRN/NOTCH3/VCL/ITGB1/PALLD/NFIB/EXT1/ACTB/ENAH/PLXND1/LAMB2/NOTCH2/DPYSL2/MACF1/NPTN/PTEN/BMPR2/SOS1 26 GO:0060562 epithelial tube morphogenesis 22/504 325/18722 7.58452850611812e-05 0.00171474551886999 EDNRA/CTHRC1/TBX2/HAND2/WNT2/COL4A1/DLC1/TGFB2/GPC3/MEF2C/MDK/EXT1/SOX4/SPRY1/PTK7/PLXND1/PKD2/CITED2/NOTCH2/RHOB/STARD13/PBX1 22 GO:0042698 ovulation cycle 9/504 68/18722 8.30909919354657e-05 0.00186867267652761 SLIT3/PDGFRA/AXL/TGFB2/MDK/ETS1/EGR1/NCOR2/ADAMTS1 9 GO:0060325 face morphogenesis 6/504 28/18722 8.40462448193749e-05 0.0018802597073989 COL1A1/PDGFRA/CRISPLD2/MMP2/RRAS/ARID5B 6 GO:0045664 regulation of neuron differentiation 16/504 196/18722 8.47059044034631e-05 0.00188514754956249 MAP1B/MEIS1/ZEB1/TCF4/JAG1/FGFR1/MEF2C/EDNRB/TIMP2/B2M/ZFHX3/DPYSL2/PTEN/PBX1/TCF12/TUG1 16 GO:0001706 endoderm formation 8/504 54/18722 9.13948019863806e-05 0.00201304117983404 COL6A1/COL5A1/COL12A1/COL5A2/COL8A1/COL4A2/MMP2/LAMB1 8 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 8/504 54/18722 9.13948019863806e-05 0.00201304117983404 TGFB2/NFIB/ETS1/EGR1/TEAD1/NR3C1/JUN/STAT3 8 GO:0072659 protein localization to plasma membrane 20/504 284/18722 9.32232397945622e-05 0.00204278412124187 EHD2/FLNA/GAS6/RAMP1/SLMAP/RAP2A/CD81/ITGB1/MYADM/ACTB/ATP2B4/SPTBN1/RHOQ/FAM126A/SEC23A/PREPL/ROCK2/PIK3R1/MACF1/RAB11FIP2 20 GO:0001656 metanephros development 10/504 85/18722 9.37931206965657e-05 0.00204478573845115 PDGFRB/PDGFRA/GPC3/SPRY1/EGR1/FBN1/LAMB2/PKD2/PDGFA/WWTR1 10 GO:0014897 striated muscle hypertrophy 11/504 102/18722 9.44652853428446e-05 0.00204622616648918 IGFBP5/HAND2/FOXO1/SORBS2/PDLIM5/LMCD1/IL6ST/ATP2B4/ROCK2/MEF2A/AKAP13 11 GO:0001666 response to hypoxia 21/504 307/18722 9.48169391445955e-05 0.00204622616648918 THBS1/CRYAB/COX4I2/EDNRA/MYOCD/TGFB2/MMP2/SLC8A1/ETS1/MALAT1/CAV1/EGR1/CITED2/HIPK2/ZFP36L1/EIF4EBP1/HSP90B1/ROCK2/PTEN/PLOD2/SOD3 21 GO:0048251 elastic fiber assembly 4/504 10/18722 9.57910918216097e-05 0.00205405871513722 MYH11/EFEMP2/EMILIN1/FBLN5 4 GO:0051897 positive regulation of protein kinase B signaling 12/504 120/18722 9.61412925409416e-05 0.00205405871513722 IGFBP5/THBS1/SEMA5A/GAS6/AXL/HIP1/MTDH/FGFR1/ITGB1/IGF2/FERMT2/PDGFA 12 GO:0003018 vascular process in circulatory system 19/504 263/18722 9.92676156211082e-05 0.00211030110223381 ACTA2/ITGA1/AKAP12/AGTR1/EDNRA/PRKG1/PDE3A/ARHGAP42/SLC8A1/EXT1/EDNRB/TJP1/ATP2B4/CAV1/SLC38A2/FERMT2/ROCK2/BMPR2/SOD3 19 GO:0001953 negative regulation of cell-matrix adhesion 7/504 41/18722 9.98965758154526e-05 0.00211315875474965 THBS1/APOD/DLC1/JAG1/MAP4K4/PIK3R1/PTEN 7 GO:0050878 regulation of body fluid levels 24/504 379/18722 0.000102839350058467 0.00214604207697943 COL3A1/MYL9/THBS1/PRKG1/PDGFRA/FLNA/GAS6/AXL/TFPI/VCL/EXT1/EDNRB/ACTB/IL6ST/SERPING1/MYH9/CAV1/CSRP1/HSPB1/NCOR2/TLN1/PDGFA/XBP1/ACTG1 24 GO:0003209 cardiac atrium morphogenesis 6/504 29/18722 0.000103579103313695 0.00214604207697943 WNT2/TGFB2/SOX4/NOTCH2/BMPR2/SOS1 6 GO:0035023 regulation of Rho protein signal transduction 10/504 86/18722 0.000103622767600931 0.00214604207697943 COL3A1/PDGFRB/KANK2/DLC1/ARHGAP42/LPAR1/ITGB1/EPS8/STARD13/AKAP13 10 GO:0001704 formation of primary germ layer 12/504 121/18722 0.00010417107064949 0.00214604207697943 COL6A1/COL5A1/COL12A1/COL5A2/COL8A1/COL4A2/MMP2/TWSG1/ITGB1/LAMB1/PRKAR1A/BMPR2 12 GO:0043244 regulation of protein-containing complex disassembly 12/504 121/18722 0.00010417107064949 0.00214604207697943 MAP1B/LMOD1/SEMA5A/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/SVIL/TAOK1 12 GO:0061614 pri-miRNA transcription by RNA polymerase II 8/504 55/18722 0.000104464486780183 0.00214604207697943 TGFB2/NFIB/ETS1/EGR1/TEAD1/NR3C1/JUN/STAT3 8 GO:0030099 myeloid cell differentiation 24/504 381/18722 0.000111468174796147 0.00227896416700448 MEIS1/JAG1/GPC3/MEF2C/CD81/ETS1/MYH9/B2M/SH3PXD2A/FBN1/ACTN1/CITED2/HIPK2/SMAD5/ZFP36L1/NOTCH2/IFI16/ZFP36/KMT2E/ISG15/JUN/STAT3/PIK3R1/RBFOX2 24 GO:0014896 muscle hypertrophy 11/504 104/18722 0.000112704184389837 0.0022823932696577 IGFBP5/HAND2/FOXO1/SORBS2/PDLIM5/LMCD1/IL6ST/ATP2B4/ROCK2/MEF2A/AKAP13 11 GO:0060419 heart growth 11/504 104/18722 0.000112704184389837 0.0022823932696577 TBX2/WNT2/MEIS1/TGFB2/SORBS2/PDLIM5/MEF2C/CITED2/PRKAR1A/PTEN/AKAP13 11 GO:0032355 response to estradiol 13/504 141/18722 0.000114829456048638 0.00229283301727024 COL1A1/IGFBP2/PDGFRB/CRYAB/MAP1B/WFDC1/TFPI/TXNIP/NR2F2/ETS1/NCOR2/STAT3/PTEN 13 GO:0035296 regulation of tube diameter 13/504 141/18722 0.000114829456048638 0.00229283301727024 ACTA2/ITGA1/AGTR1/EDNRA/PRKG1/ARHGAP42/SLC8A1/EXT1/EDNRB/CAV1/ROCK2/BMPR2/SOD3 13 GO:0097746 blood vessel diameter maintenance 13/504 141/18722 0.000114829456048638 0.00229283301727024 ACTA2/ITGA1/AGTR1/EDNRA/PRKG1/ARHGAP42/SLC8A1/EXT1/EDNRB/CAV1/ROCK2/BMPR2/SOD3 13 GO:0043410 positive regulation of MAPK cascade 28/504 480/18722 0.00011545280023384 0.0022945572809265 PLA2G2A/THBS1/PDGFRB/IGFBP4/AKAP12/HAND2/PDGFRA/HGF/GAS6/TGFB2/LPAR1/FGFR1/CD81/SORBS3/TIMP2/IGF2/CAV2/HIPK2/FERMT2/NOTCH2/PDGFA/ROCK2/ADAM9/NPTN/PJA2/PTEN/TAOK1/AKAP13 28 GO:0045214 sarcomere organization 7/504 42/18722 0.000117124316242465 0.0023063235175302 TPM1/ITGB1/CFL2/CSRP1/PRKAR1A/ACTG1/AKAP13 7 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 7/504 42/18722 0.000117124316242465 0.0023063235175302 TGFB2/ETS1/EGR1/TEAD1/NR3C1/JUN/STAT3 7 GO:0045599 negative regulation of fat cell differentiation 8/504 56/18722 0.000119042249154237 0.00233333729649565 TGFB1I1/RUNX1T1/ENPP1/FOXO1/JAG1/FERMT2/CCDC85B/WWTR1 8 GO:0032231 regulation of actin filament bundle assembly 11/504 105/18722 0.000122896229962741 0.00239606201383752 SYNPO2/FLNA/TPM1/DLC1/LPAR1/SORBS3/TJP1/FERMT2/ROCK2/PIK3R1/ACTG1 11 GO:0035150 regulation of tube size 13/504 142/18722 0.000123363829404225 0.00239606201383752 ACTA2/ITGA1/AGTR1/EDNRA/PRKG1/ARHGAP42/SLC8A1/EXT1/EDNRB/CAV1/ROCK2/BMPR2/SOD3 13 GO:0051494 negative regulation of cytoskeleton organization 14/504 162/18722 0.000127230531061197 0.00245998216843662 MAP1B/LMOD1/PLEKHH2/DLC1/MYADM/TMSB4X/TJP1/EPS8/SPTBN1/LIMA1/GSN/SVIL/PIK3R1/TAOK1 14 GO:1901880 negative regulation of protein depolymerization 9/504 72/18722 0.000130499085786117 0.00251181348452288 MAP1B/LMOD1/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/SVIL/TAOK1 9 GO:0030010 establishment of cell polarity 13/504 143/18722 0.000132439641156874 0.00253773357248127 MAP1B/ITGB1/MYH9/SPRY1/PTK7/GSN/MAP4/ROCK2/FAT1/MSN/AMOTL2/MYO9A/RAB11FIP2 13 GO:0002062 chondrocyte differentiation 11/504 106/18722 0.000133862814870224 0.00255355271401994 COL27A1/SULF2/MAF/MEF2C/MDK/NFIB/EXT1/SOX6/SERPINH1/TGFBI/BMPR2 11 GO:0010171 body morphogenesis 7/504 43/18722 0.000136688592021289 0.00258438209604853 COL1A1/PDGFRA/CRISPLD2/MMP2/RRAS/GPC3/ARID5B 7 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 7/504 43/18722 0.000136688592021289 0.00258438209604853 CNN1/PRKG1/MYOCD/EFEMP2/TPM1/MEF2C/PTEN 7 GO:0014910 regulation of smooth muscle cell migration 10/504 89/18722 0.000138499110558586 0.00260707797099929 IGFBP5/PDGFRB/PRKG1/MYOCD/TPM1/IGFBP3/MEF2C/MDK/ADAMTS1/PDGFA 10 GO:0046718 viral entry into host cell 13/504 144/18722 0.000142085001023658 0.00266284740953549 AGTR1/GAS6/AXL/LGALS1/IFITM2/IFITM3/IFITM1/CD81/ITGB1/CAV1/GSN/CAV2/KPNA3 13 GO:0060348 bone development 16/504 205/18722 0.000143280130077867 0.00267351963241366 COL1A1/PLS3/COL27A1/MEIS1/BGN/SULF2/MEF2C/EXT1/SERPINH1/FBN1/CITED2/SMAD5/NOTCH2/BMPR2/DHRS3/AKAP13 16 GO:0032836 glomerular basement membrane development 4/504 11/18722 0.000147329006905922 0.00273711672395219 NID1/SULF2/EXT1/LAMB2 4 GO:0007411 axon guidance 17/504 227/18722 0.000148141629188194 0.00274029948710456 LAMA2/SLIT3/SEMA5A/CHN1/NEXN/NOTCH3/PALLD/NFIB/EXT1/ENAH/PLXND1/LAMB2/NOTCH2/DPYSL2/NPTN/BMPR2/SOS1 17 GO:0048872 homeostasis of number of cells 19/504 272/18722 0.000154054292527776 0.00283738789642753 PLA2G2A/AXL/MEF2C/EXT1/FSTL1/ETS1/SOX4/B2M/CITED2/HIPK2/SMAD5/ZFP36L1/ZFP36/KMT2E/ISG15/STAT3/RBFOX2/AKT3/SOS1 19 GO:0097485 neuron projection guidance 17/504 228/18722 0.000156186322063071 0.00286430967457297 LAMA2/SLIT3/SEMA5A/CHN1/NEXN/NOTCH3/PALLD/NFIB/EXT1/ENAH/PLXND1/LAMB2/NOTCH2/DPYSL2/NPTN/BMPR2/SOS1 17 GO:0050679 positive regulation of epithelial cell proliferation 16/504 207/18722 0.000160292829562482 0.00292705666974566 AGTR1/SEMA5A/WNT2/FGFR1/MDK/LAMC1/IGF2/CAV2/LAMB1/NOTCH2/HTRA1/XBP1/STAT3/NR4A1/BMPR2/AKT3 16 GO:0042542 response to hydrogen peroxide 13/504 146/18722 0.000163202331815662 0.00296750452701414 COL1A1/PDGFRB/CRYAB/HGF/AXL/TXNIP/FOXO1/SLC8A1/ETS1/RHOB/MAP1LC3A/JUN/ADAM9 13 GO:0008064 regulation of actin polymerization or depolymerization 15/504 187/18722 0.000169948246804163 0.00307707143472115 LMOD1/ELN/SEMA5A/PLEKHH2/MYADM/TMSB4X/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/CDC42EP3/NCKAP1/SVIL 15 GO:0030832 regulation of actin filament length 15/504 188/18722 0.00018021852118532 0.003218312560424 LMOD1/ELN/SEMA5A/PLEKHH2/MYADM/TMSB4X/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/CDC42EP3/NCKAP1/SVIL 15 GO:0030835 negative regulation of actin filament depolymerization 7/504 45/18722 0.000183764995986525 0.003218312560424 LMOD1/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/SVIL 7 GO:0035272 exocrine system development 7/504 45/18722 0.000183764995986525 0.003218312560424 HGF/TGFB2/TWSG1/NFIB/PLXND1/IGF2/PDGFA 7 GO:0036293 response to decreased oxygen levels 21/504 322/18722 0.000184075382687655 0.003218312560424 THBS1/CRYAB/COX4I2/EDNRA/MYOCD/TGFB2/MMP2/SLC8A1/ETS1/MALAT1/CAV1/EGR1/CITED2/HIPK2/ZFP36L1/EIF4EBP1/HSP90B1/ROCK2/PTEN/PLOD2/SOD3 21 GO:0007435 salivary gland morphogenesis 6/504 32/18722 0.000184527633349843 0.003218312560424 HGF/TGFB2/TWSG1/NFIB/PLXND1/PDGFA 6 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 6/504 32/18722 0.000184527633349843 0.003218312560424 THBS1/TGFB1I1/MYOCD/ZEB2/CITED2/HIPK2 6 GO:0035767 endothelial cell chemotaxis 6/504 32/18722 0.000184527633349843 0.003218312560424 THBS1/SEMA5A/FGFR1/TMSB4X/HSPB1/NR4A1 6 GO:0060323 head morphogenesis 6/504 32/18722 0.000184527633349843 0.003218312560424 COL1A1/PDGFRA/CRISPLD2/MMP2/RRAS/ARID5B 6 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 6/504 32/18722 0.000184527633349843 0.003218312560424 THBS1/TGFB1I1/MYOCD/ZEB2/CITED2/HIPK2 6 GO:0014812 muscle cell migration 11/504 110/18722 0.000186448860783636 0.0032386015533678 IGFBP5/PDGFRB/PRKG1/MYOCD/TPM1/IGFBP3/MEF2C/MDK/ADAMTS1/PDGFA/PARVA 11 GO:0016055 Wnt signaling pathway 26/504 444/18722 0.000189193276938077 0.00327296709456033 COL1A1/IGFBP2/IGFBP4/SEMA5A/ADGRA2/CTHRC1/TGFB1I1/WNT2/NXN/ZEB2/SULF2/GPC3/MDK/EXT1/SOX4/CAV1/EGR1/PTK7/PKD2/FERMT2/RBMS3/DAAM1/WWTR1/AMOTL2/MACF1/PTEN 26 GO:0034101 erythrocyte homeostasis 12/504 129/18722 0.000191844756290776 0.00330545420818745 AXL/ETS1/B2M/CITED2/HIPK2/SMAD5/ZFP36L1/ZFP36/KMT2E/ISG15/STAT3/RBFOX2 12 GO:0060038 cardiac muscle cell proliferation 8/504 60/18722 0.00019518376992908 0.00334947891127292 TBX2/WNT2/MEIS1/TGFB2/MEF2C/CITED2/PRKAR1A/PTEN 8 GO:0035455 response to interferon-alpha 5/504 21/18722 0.000197304215869189 0.00337232365763618 GAS6/AXL/IFITM2/IFITM3/IFITM1 5 GO:0014855 striated muscle cell proliferation 9/504 76/18722 0.000198654609172235 0.0033818770716851 TBX2/WNT2/MEIS1/TGFB2/MEF2C/CITED2/PRKAR1A/STAT3/PTEN 9 GO:0001938 positive regulation of endothelial cell proliferation 11/504 111/18722 0.000202037636295735 0.00342582071385585 AGTR1/SEMA5A/WNT2/FGFR1/MDK/IGF2/CAV2/STAT3/NR4A1/BMPR2/AKT3 11 GO:0198738 cell-cell signaling by wnt 26/504 446/18722 0.000203009616925427 0.00342869602024645 COL1A1/IGFBP2/IGFBP4/SEMA5A/ADGRA2/CTHRC1/TGFB1I1/WNT2/NXN/ZEB2/SULF2/GPC3/MDK/EXT1/SOX4/CAV1/EGR1/PTK7/PKD2/FERMT2/RBMS3/DAAM1/WWTR1/AMOTL2/MACF1/PTEN 26 GO:0001974 blood vessel remodeling 7/504 46/18722 0.000211781225162414 0.00356276053196454 FLNA/AXL/BGN/JAG1/MEF2C/EXT1/BMPR2 7 GO:0003207 cardiac chamber formation 4/504 12/18722 0.000216299977776028 0.00361035080092566 TBX2/HAND2/MEF2C/SOX4 4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway 4/504 12/18722 0.000216299977776028 0.00361035080092566 COL1A1/DDR2/COL4A1/COL4A2 4 GO:0030865 cortical cytoskeleton organization 8/504 61/18722 0.000219432081741774 0.00364837854195564 EHD2/EPB41L2/RHOQ/NCKAP1/RHOB/TLN1/RND3/ROCK2 8 GO:0007162 negative regulation of cell adhesion 20/504 303/18722 0.000222285942710755 0.00368150322946921 COL1A1/THBS1/SEMA5A/APOD/PRKG1/LRRC32/LGALS1/DLC1/PAG1/TWSG1/JAG1/MDK/MYADM/ACTN4/PLXND1/TGFBI/MAP4K4/PRKAR1A/PIK3R1/PTEN 20 GO:0044409 entry into host 13/504 151/18722 0.000228148657575835 0.00376401240857739 AGTR1/GAS6/AXL/LGALS1/IFITM2/IFITM3/IFITM1/CD81/ITGB1/CAV1/GSN/CAV2/KPNA3 13 GO:0035850 epithelial cell differentiation involved in kidney development 7/504 47/18722 0.000243142495494217 0.00397127725824135 ACTA2/JAG1/MEF2C/EXT1/LAMB2/NOTCH2/WWTR1 7 GO:0045646 regulation of erythrocyte differentiation 7/504 47/18722 0.000243142495494217 0.00397127725824135 ETS1/B2M/ZFP36L1/ZFP36/ISG15/STAT3/RBFOX2 7 GO:0030509 BMP signaling pathway 13/504 152/18722 0.000243499799124557 0.00397127725824135 TGFB2/TWSG1/GPC3/EXT1/FSTL1/EGR1/FBN1/HIPK2/SMAD5/NOTCH2/HTRA1/BMPR2/CRIM1 13 GO:0072574 hepatocyte proliferation 5/504 22/18722 0.000249719047783407 0.00404185413325189 LIMS2/SULF2/MDK/NOTCH2/XBP1 5 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 5/504 22/18722 0.000249719047783407 0.00404185413325189 LIMS2/SULF2/MDK/NOTCH2/XBP1 5 GO:1901654 response to ketone 15/504 194/18722 0.000253871957303013 0.00409356556058783 IGFBP7/THBS1/SLIT3/GAS6/ADCY3/TGFB2/TXNIP/FOXO1/CAV1/NR3C1/TSPO/ROCK2/MSN/FBXO32/AHR 15 GO:0009612 response to mechanical stimulus 16/504 216/18722 0.000260486864307812 0.00418443748566647 COL3A1/COL1A1/DCN/THBS1/IGFBP2/MAP1B/TXNIP/SLC8A1/MDK/ETS1/SLC38A2/CNN2/GSN/PKD2/CITED2/JUN 16 GO:0007431 salivary gland development 6/504 34/18722 0.000261664584375071 0.00418761336717108 HGF/TGFB2/TWSG1/NFIB/PLXND1/PDGFA 6 GO:0008154 actin polymerization or depolymerization 16/504 217/18722 0.000274410129481425 0.00437520329579898 LMOD1/ELN/SEMA5A/PLEKHH2/MYADM/TMSB4X/EPS8/SPTBN1/LIMA1/ENAH/GSN/DSTN/CFL2/CDC42EP3/NCKAP1/SVIL 16 GO:0030278 regulation of ossification 11/504 115/18722 0.00027590453630424 0.00438267689081048 MGP/DDR2/ENPP1/TGFB2/MEF2C/SLC8A1/MDK/ISG15/BMPR2/PBX1/DHRS3 11 GO:0071229 cellular response to acid chemical 9/504 80/18722 0.000294107601682663 0.00465089081019058 COL1A2/COL1A1/COL6A1/PDGFRA/COL5A2/COL4A1/MMP2/PKD2/XBP1 9 GO:0034614 cellular response to reactive oxygen species 13/504 155/18722 0.000294966395872139 0.00465089081019058 PDGFRA/HGF/AXL/TPM1/FBLN5/FOXO1/MMP2/ETS1/PKD2/RHOB/MAP1LC3A/JUN/SOD3 13 GO:0034405 response to fluid shear stress 6/504 35/18722 0.000308694475917125 0.00484945402791867 PDGFRB/MEF2C/ETS1/PKD2/CITED2/ADAM9 6 GO:0072576 liver morphogenesis 5/504 23/18722 0.000312072142925282 0.00487962579989967 LIMS2/SULF2/MDK/NOTCH2/XBP1 5 GO:0043624 cellular protein complex disassembly 12/504 136/18722 0.000314040977058836 0.00487962579989967 MAP1B/LMOD1/SEMA5A/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/SVIL/TAOK1 12 GO:0072073 kidney epithelium development 12/504 136/18722 0.000314040977058836 0.00487962579989967 KANK2/JAG1/GPC3/MEF2C/EXT1/SPRY1/LAMB2/PKD2/SMAD5/NOTCH2/WWTR1/PBX1 12 GO:0031099 regeneration 15/504 198/18722 0.000316293841204019 0.00489682457777092 THY1/MAP1B/NNMT/APOD/HGF/FLNA/GAS6/AXL/SULF2/CD81/MDK/LAMB2/TSPO/MAP4K4/PTEN 15 GO:0034599 cellular response to oxidative stress 19/504 288/18722 0.000318898722296212 0.00491932938762351 PDGFRA/HGF/AXL/TPM1/FBLN5/FOXO1/MMP2/MGST1/ETS1/PKD2/HSPB1/RHOB/MAP1LC3A/JUN/GPX8/NCOA7/NFE2L1/SLC25A24/SOD3 19 GO:0030522 intracellular receptor signaling pathway 18/504 265/18722 0.000320563846787233 0.00492722776015052 NR2F1/PLPP1/KANK2/NR2F2/NR3C1/ACTN4/CITED2/NCOR2/DDX17/CLOCK/STAT3/CTBP2/NR4A1/RBFOX2/ZMIZ1/DHRS3/AHR/DCBLD2 18 GO:0003300 cardiac muscle hypertrophy 10/504 99/18722 0.00033411854151154 0.00511716318236133 HAND2/FOXO1/SORBS2/PDLIM5/LMCD1/IL6ST/ATP2B4/ROCK2/MEF2A/AKAP13 10 GO:0052547 regulation of peptidase activity 26/504 461/18722 0.000338554812304121 0.00516658826062682 COL6A3/THBS1/CRYAB/WFDC1/PCOLCE/ANTXR1/HGF/GAS6/TFPI/TIMP1/DLC1/A2M/UACA/HIP1/GPC3/SERPING1/CAV1/TIMP2/SERPINH1/TIMP3/GSN/IFI16/ROCK2/STAT3/NR4A1/CRIM1 26 GO:0071375 cellular response to peptide hormone stimulus 19/504 290/18722 0.000347686556401991 0.00528706283098117 MAP1B/AGTR1/RARRES2/ENPP1/FOXO1/CAV1/RHOQ/IGF2/FBN1/CAV2/ZFP36L1/ROCK2/XBP1/STAT3/PIK3R1/NR4A1/PTEN/PTPRA/EIF4EBP2 19 GO:0009410 response to xenobiotic stimulus 26/504 462/18722 0.000349929546555589 0.00530230124975897 COL1A1/IGFBP2/MAP1B/WFDC1/NNMT/COL18A1/APOD/PDE3A/GAS6/LGALS1/TGFB2/TXNIP/RAP2A/MGST1/MEF2C/SLC8A1/MDK/TIMP2/B2M/TSPO/JUN/STAT3/PTEN/PPP1R12A/GSTM3/AHR 26 GO:0043242 negative regulation of protein-containing complex disassembly 9/504 82/18722 0.000354467966733512 0.00535209053658056 MAP1B/LMOD1/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/SVIL/TAOK1 9 GO:0060337 type I interferon signaling pathway 7/504 50/18722 0.000360245076594094 0.00541574797314067 IFITM2/IFI27/IFITM3/IFITM1/JAK1/ISG15/STAT2 7 GO:0003230 cardiac atrium development 6/504 36/18722 0.000362100470109248 0.00541574797314067 WNT2/TGFB2/SOX4/NOTCH2/BMPR2/SOS1 6 GO:0110020 regulation of actomyosin structure organization 10/504 100/18722 0.000362486290736773 0.00541574797314067 TPM1/DLC1/LPAR1/SORBS3/TJP1/FERMT2/ROCK2/PIK3R1/ACTG1/AKAP13 10 GO:0045598 regulation of fat cell differentiation 12/504 139/18722 0.000383747159222578 0.00570035869561574 RARRES2/TGFB1I1/RUNX1T1/ENPP1/FOXO1/JAG1/FERMT2/ZFP36L1/ZFP36/CCDC85B/WWTR1/XBP1 12 GO:0061162 establishment of monopolar cell polarity 5/504 24/18722 0.000385537950627884 0.00570035869561574 MAP1B/PTK7/FAT1/MSN/MYO9A 5 GO:2001026 regulation of endothelial cell chemotaxis 5/504 24/18722 0.000385537950627884 0.00570035869561574 THBS1/SEMA5A/FGFR1/TMSB4X/HSPB1 5 GO:0030218 erythrocyte differentiation 11/504 120/18722 0.000399122899792903 0.00584629531597715 ETS1/B2M/CITED2/HIPK2/SMAD5/ZFP36L1/ZFP36/KMT2E/ISG15/STAT3/RBFOX2 11 GO:0048593 camera-type eye morphogenesis 11/504 120/18722 0.000399122899792903 0.00584629531597715 THY1/TBX2/WNT2/MEIS1/COL8A1/JAG1/CITED2/HIPK2/NOTCH2/FAT1/MAN2A1 11 GO:0019058 viral life cycle 20/504 317/18722 0.000399512808861532 0.00584629531597715 AGTR1/GAS6/AXL/LGALS1/NFIA/IFITM2/IFI27/IFITM3/IFITM1/CD81/ITGB1/CAV1/GSN/CAV2/IFI16/ISG15/ROCK2/CTBP2/STOM/KPNA3 20 GO:0032964 collagen biosynthetic process 7/504 51/18722 0.00040800709653082 0.00595021953404844 COL1A1/COL5A1/PDGFRB/EMILIN1/VIM/SERPINH1/P3H4 7 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 4/504 14/18722 0.000419049007696853 0.00608971566574577 PDGFRB/MYOCD/HIP1/PDGFA 4 GO:0003176 aortic valve development 6/504 37/18722 0.000422467444875914 0.00608971566574577 SLIT3/ELN/EMILIN1/JAG1/ROCK2/BMPR2 6 GO:0048009 insulin-like growth factor receptor signaling pathway 6/504 37/18722 0.000422467444875914 0.00608971566574577 IGFBP5/IGFBP2/IGFBP4/IGFBP3/PIK3R1/CRIM1 6 GO:0002088 lens development in camera-type eye 9/504 84/18722 0.000424698167187512 0.00608971566574577 CRYAB/WNT2/MEIS1/VIM/MAF/SPRY1/CITED2/HIPK2/FAT1 9 GO:0045445 myoblast differentiation 9/504 84/18722 0.000424698167187512 0.00608971566574577 TBX2/MYOCD/LGALS1/IGFBP3/JAG1/MEF2C/ZFP36L1/MBNL1/DDX17 9 GO:0043500 muscle adaptation 11/504 121/18722 0.000428618082707243 0.00612536811842157 IGFBP5/GATM/HAND2/FOXO1/LMCD1/IL6ST/ATP2B4/GSN/ROCK2/MEF2A/FBXO32 11 GO:0051495 positive regulation of cytoskeleton organization 16/504 226/18722 0.000431542108408417 0.00614659809743056 SYNPO2/MAP1B/LMOD1/SEMA5A/FLNA/TPM1/LPAR1/SORBS3/GSN/DSTN/CFL2/CDC42EP3/FERMT2/NCKAP1/ARL3/ROCK2 16 GO:0022411 cellular component disassembly 25/504 443/18722 0.000434061978223283 0.00616194961112322 MAP1B/LMOD1/SEMA5A/ADAMTS5/DDR2/PLEKHH2/CTSK/MMP2/HSPA2/LAMC1/ETS1/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/TSPO/VMP1/MAP4K4/SVIL/MAP1LC3A/PIK3R1/TAOK1/TOMM7 25 GO:0010718 positive regulation of epithelial to mesenchymal transition 7/504 52/18722 0.000460696501331889 0.00649688498412925 COL1A1/TGFB1I1/TGFB2/JAG1/MDK/FERMT2/WWTR1 7 GO:0071357 cellular response to type I interferon 7/504 52/18722 0.000460696501331889 0.00649688498412925 IFITM2/IFI27/IFITM3/IFITM1/JAK1/ISG15/STAT2 7 GO:0055013 cardiac muscle cell development 9/504 85/18722 0.000463884291114071 0.00649894287190303 MYH11/PDGFRB/PDGFRA/SORBS2/PDLIM5/SGCB/SLC8A1/MEF2A/AKAP13 9 GO:0060021 roof of mouth development 9/504 85/18722 0.000463884291114071 0.00649894287190303 TBX2/HAND2/PDGFRA/LRRC32/TGFB2/TSHZ1/ARID5B/DHRS3/SOS1 9 GO:0061339 establishment or maintenance of monopolar cell polarity 5/504 25/18722 0.000471344190934636 0.00651797322933236 MAP1B/PTK7/FAT1/MSN/MYO9A 5 GO:0072012 glomerulus vasculature development 5/504 25/18722 0.000471344190934636 0.00651797322933236 ACTA2/PDGFRB/PDGFRA/EGR1/NOTCH2 5 GO:1905048 regulation of metallopeptidase activity 5/504 25/18722 0.000471344190934636 0.00651797322933236 ANTXR1/TIMP1/TIMP2/TIMP3/STAT3 5 GO:1905564 positive regulation of vascular endothelial cell proliferation 5/504 25/18722 0.000471344190934636 0.00651797322933236 FGFR1/MDK/IGF2/STAT3/AKT3 5 GO:0048863 stem cell differentiation 15/504 206/18722 0.000481544345257742 0.00663754512027848 SEMA5A/EDNRA/TBX2/HAND2/MYOCD/PDGFRA/TGFB2/A2M/JAG1/MEF2C/EXT1/EDNRB/SOX6/CITED2/STAT3 15 GO:0003231 cardiac ventricle development 11/504 123/18722 0.000493109530327224 0.00677510296812936 SLIT3/HAND2/MYOCD/TPM1/TGFB2/JAG1/MEF2C/SOX4/PTK7/CITED2/BMPR2 11 GO:0045444 fat cell differentiation 16/504 229/18722 0.000498784034892202 0.00682544945617779 RARRES2/TGFB1I1/RUNX1T1/PDGFRA/ENPP1/FOXO1/JAG1/FERMT2/ZFP36L1/ARID5B/ZFP36/CCDC85B/WWTR1/XBP1/CTBP2/NR4A1 16 GO:0002040 sprouting angiogenesis 14/504 185/18722 0.000501565909019384 0.00682544945617779 THBS1/AGTR1/SEMA5A/ADGRA2/ADAMTS9/ITGB1/TJP1/JAK1/HDAC7/STARD13/PARVA/EPN2/NR4A1/AKT3 14 GO:0051896 regulation of protein kinase B signaling 14/504 185/18722 0.000501565909019384 0.00682544945617779 IGFBP5/THBS1/SEMA5A/GAS6/AXL/HIP1/MTDH/RRAS/FGFR1/ITGB1/IGF2/FERMT2/PDGFA/PTEN 14 GO:0050680 negative regulation of epithelial cell proliferation 13/504 164/18722 0.00050848453753409 0.0068976331075656 SPARC/THBS1/WFDC1/LIMS2/TGFB2/NR2F2/GPC3/MEF2C/NFIB/CAV1/B2M/CAV2/PTEN 13 GO:0008217 regulation of blood pressure 14/504 186/18722 0.000529352368470341 0.00715798313441065 COL1A2/ACTA2/AGTR1/RARRES2/EDNRA/CAMK2N1/GAS6/TPM1/ARHGAP42/KCNK6/NR2F2/EXT1/EDNRB/BMPR2 14 GO:0048608 reproductive structure development 24/504 424/18722 0.000538291744098548 0.00721662486504861 DCN/PDGFRB/SLIT3/MYOCD/PDGFRA/WNT2/FLNA/AXL/TGFB2/NR2F2/MGST1/CRIP1/IGF2/FNDC3A/PKD2/CITED2/ZFP36L1/NOTCH2/HTRA1/ARID5B/ADAMTS1/ATRX/PTEN/BMPR2 24 GO:0071772 response to BMP 13/504 165/18722 0.000538755752855255 0.00721662486504861 TGFB2/TWSG1/GPC3/EXT1/FSTL1/EGR1/FBN1/HIPK2/SMAD5/NOTCH2/HTRA1/BMPR2/CRIM1 13 GO:0071773 cellular response to BMP stimulus 13/504 165/18722 0.000538755752855255 0.00721662486504861 TGFB2/TWSG1/GPC3/EXT1/FSTL1/EGR1/FBN1/HIPK2/SMAD5/NOTCH2/HTRA1/BMPR2/CRIM1 13 GO:0060413 atrial septum morphogenesis 4/504 15/18722 0.00055932725840074 0.00739939744627357 TGFB2/SOX4/NOTCH2/BMPR2 4 GO:0072224 metanephric glomerulus development 4/504 15/18722 0.00055932725840074 0.00739939744627357 PDGFRB/PDGFRA/EGR1/LAMB2 4 GO:2000345 regulation of hepatocyte proliferation 4/504 15/18722 0.00055932725840074 0.00739939744627357 LIMS2/SULF2/MDK/XBP1 4 GO:2001028 positive regulation of endothelial cell chemotaxis 4/504 15/18722 0.00055932725840074 0.00739939744627357 SEMA5A/FGFR1/TMSB4X/HSPB1 4 GO:0014829 vascular associated smooth muscle contraction 5/504 26/18722 0.000570768211155746 0.00752744619218673 ACTA2/EDNRA/ARHGAP42/SLC8A1/EDNRB 5 GO:0030038 contractile actin filament bundle assembly 10/504 106/18722 0.000578094139463281 0.00757728913474418 ELN/TPM1/DLC1/LPAR1/SORBS3/TJP1/FERMT2/ROCK2/PIK3R1/ACTG1 10 GO:0043149 stress fiber assembly 10/504 106/18722 0.000578094139463281 0.00757728913474418 ELN/TPM1/DLC1/LPAR1/SORBS3/TJP1/FERMT2/ROCK2/PIK3R1/ACTG1 10 GO:0061458 reproductive system development 24/504 427/18722 0.00059461668744163 0.00776546027203357 DCN/PDGFRB/SLIT3/MYOCD/PDGFRA/WNT2/FLNA/AXL/TGFB2/NR2F2/MGST1/CRIP1/IGF2/FNDC3A/PKD2/CITED2/ZFP36L1/NOTCH2/HTRA1/ARID5B/ADAMTS1/ATRX/PTEN/BMPR2 24 GO:0060070 canonical Wnt signaling pathway 19/504 303/18722 0.00059608494482261 0.00776546027203357 COL1A1/IGFBP2/IGFBP4/SEMA5A/ADGRA2/CTHRC1/WNT2/ZEB2/SULF2/GPC3/MDK/EXT1/SOX4/CAV1/EGR1/PTK7/RBMS3/WWTR1/PTEN 19 GO:0043491 protein kinase B signaling 15/504 211/18722 0.000618529281470587 0.008033360546273 IGFBP5/THBS1/SEMA5A/GAS6/AXL/HIP1/MTDH/RRAS/FGFR1/ITGB1/IGF2/FERMT2/ZFP36L1/PDGFA/PTEN 15 GO:0071230 cellular response to amino acid stimulus 8/504 71/18722 0.000627134646120423 0.00812044346325021 COL1A2/COL1A1/COL6A1/PDGFRA/COL5A2/COL4A1/MMP2/XBP1 8 GO:0030900 forebrain development 22/504 379/18722 0.000650178262482785 0.0083412523664755 COL3A1/SEMA5A/PRKG1/FLNA/AXL/DLC1/TWSG1/NR2F2/SLC8A1/MDK/NFIB/EXT1/ETS1/ATP2B4/BTBD3/SLC38A2/B2M/LAMB1/TACC1/ATRX/PTEN/ZMIZ1 22 GO:0030866 cortical actin cytoskeleton organization 6/504 40/18722 0.000651571551919664 0.0083412523664755 EHD2/EPB41L2/RHOQ/NCKAP1/TLN1/ROCK2 6 GO:0000768 syncytium formation by plasma membrane fusion 7/504 55/18722 0.000651995855465204 0.0083412523664755 ADAMTS5/EHD2/CD81/MYH9/ADAM12/SH3PXD2A/ADAM9 7 GO:0140253 cell-cell fusion 7/504 55/18722 0.000651995855465204 0.0083412523664755 ADAMTS5/EHD2/CD81/MYH9/ADAM12/SH3PXD2A/ADAM9 7 GO:0031214 biomineral tissue development 13/504 169/18722 0.000675548820432075 0.00861677644688435 COL1A2/COL1A1/MGP/DDR2/ENPP1/GAS6/FOXO1/GPC3/MEF2C/SLC8A1/ISG15/ROCK2/BMPR2 13 GO:0014743 regulation of muscle hypertrophy 8/504 72/18722 0.000689214091162211 0.00873890745262946 IGFBP5/HAND2/FOXO1/LMCD1/IL6ST/ATP2B4/ROCK2/MEF2A 8 GO:1903036 positive regulation of response to wounding 8/504 72/18722 0.000689214091162211 0.00873890745262946 THBS1/MYLK/FLNA/ITGB1/MDK/FERMT2/XBP1/ACTG1 8 GO:0016525 negative regulation of angiogenesis 12/504 149/18722 0.00071771060896485 0.00907330601215031 DCN/SPARC/THBS1/ADAMTS9/EMILIN1/TGFB2/COL4A2/HSPG2/ATP2B4/ADAMTS1/ROCK2/EPN2 12 GO:0032535 regulation of cellular component size 22/504 382/18722 0.000721570252301292 0.00909519082030507 MAP1B/LMOD1/ELN/SEMA5A/PLEKHH2/MYADM/TMSB4X/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/CDC42EP3/NCKAP1/SVIL/DPYSL2/MSN/MACF1/PTEN/BMPR2/AKT3 22 GO:0002693 positive regulation of cellular extravasation 4/504 16/18722 0.000729988381948456 0.00912058583644956 THY1/MDK/IL1R1/CD99 4 GO:0044849 estrous cycle 4/504 16/18722 0.000729988381948456 0.00912058583644956 MDK/ETS1/EGR1/NCOR2 4 GO:2001044 regulation of integrin-mediated signaling pathway 4/504 16/18722 0.000729988381948456 0.00912058583644956 FLNA/LIMS2/TIMP1/LIMS1 4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 6/504 41/18722 0.000746144404966099 0.00929526251434444 FLNA/LIMS2/MDK/MYADM/LIMS1/FERMT2 6 GO:0110148 biomineralization 13/504 171/18722 0.00075424420946723 0.00936530377861071 COL1A2/COL1A1/MGP/DDR2/ENPP1/GAS6/FOXO1/GPC3/MEF2C/SLC8A1/ISG15/ROCK2/BMPR2 13 GO:0035924 cellular response to vascular endothelial growth factor stimulus 8/504 73/18722 0.000756150199770816 0.00936530377861071 DCN/PDGFRB/ADGRA2/PDGFRA/GAS1/ATP2B4/HSPB1/NR4A1 8 GO:0051492 regulation of stress fiber assembly 9/504 91/18722 0.000766283503389677 0.00946337979764188 TPM1/DLC1/LPAR1/SORBS3/TJP1/FERMT2/ROCK2/PIK3R1/ACTG1 9 GO:0010466 negative regulation of peptidase activity 17/504 262/18722 0.000780485739061343 0.00961099585881591 COL6A3/THBS1/CRYAB/WFDC1/HGF/GAS6/TFPI/TIMP1/A2M/GPC3/SERPING1/TIMP2/SERPINH1/TIMP3/IFI16/NR4A1/CRIM1 17 GO:0007219 Notch signaling pathway 13/504 172/18722 0.000796396713012097 0.00972286615628768 DLK1/TBX2/TGFB2/NOTCH3/SORBS2/JAG1/IL6ST/NOTCH2/CFD/EPN2/STAT3/MAML2/ZMIZ1 13 GO:0048736 appendage development 13/504 172/18722 0.000796396713012097 0.00972286615628768 TBX2/HAND2/TGFB2/NR2F2/GPC3/EXT1/SOX4/FERMT2/NOTCH2/MBNL1/ATRX/BMPR2/PBX1 13 GO:0060173 limb development 13/504 172/18722 0.000796396713012097 0.00972286615628768 TBX2/HAND2/TGFB2/NR2F2/GPC3/EXT1/SOX4/FERMT2/NOTCH2/MBNL1/ATRX/BMPR2/PBX1 13 GO:2000181 negative regulation of blood vessel morphogenesis 12/504 151/18722 0.000807591848025751 0.00976331388782556 DCN/SPARC/THBS1/ADAMTS9/EMILIN1/TGFB2/COL4A2/HSPG2/ATP2B4/ADAMTS1/ROCK2/EPN2 12 GO:0002011 morphogenesis of an epithelial sheet 7/504 57/18722 0.000811134198497092 0.00976331388782556 COL5A1/FLNA/JAG1/FERMT2/NOTCH2/PTEN/SOS1 7 GO:0006949 syncytium formation 7/504 57/18722 0.000811134198497092 0.00976331388782556 ADAMTS5/EHD2/CD81/MYH9/ADAM12/SH3PXD2A/ADAM9 7 GO:0061005 cell differentiation involved in kidney development 7/504 57/18722 0.000811134198497092 0.00976331388782556 ACTA2/JAG1/MEF2C/EXT1/LAMB2/NOTCH2/WWTR1 7 GO:1900024 regulation of substrate adhesion-dependent cell spreading 7/504 57/18722 0.000811134198497092 0.00976331388782556 FLNA/LIMS2/MDK/MYADM/LIMS1/ACTN4/FERMT2 7 GO:0019079 viral genome replication 11/504 131/18722 0.000837943067762157 0.0100014824819768 GAS6/NFIA/IFITM2/IFI27/IFITM3/IFITM1/IFI16/ISG15/ROCK2/CTBP2/STOM 11 GO:0046683 response to organophosphorus 11/504 131/18722 0.000837943067762157 0.0100014824819768 COL1A1/IGFBP5/SPARC/PDE3A/SLC8A1/PKD2/ZFP36L1/HSP90B1/JUN/PTEN/AHR 11 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 11/504 131/18722 0.000837943067762157 0.0100014824819768 TGFB1I1/EMILIN1/TWSG1/CAV1/SPRY1/LTBP1/FBN1/CAV2/HIPK2/HTRA1/CRIM1 11 GO:0014912 negative regulation of smooth muscle cell migration 6/504 42/18722 0.000850981086420038 0.0101288083071666 IGFBP5/PRKG1/MYOCD/TPM1/IGFBP3/MEF2C 6 GO:1901343 negative regulation of vasculature development 12/504 152/18722 0.000855942595074422 0.0101595630798695 DCN/SPARC/THBS1/ADAMTS9/EMILIN1/TGFB2/COL4A2/HSPG2/ATP2B4/ADAMTS1/ROCK2/EPN2 12 GO:0045185 maintenance of protein location 9/504 93/18722 0.000897007744278573 0.0106110611238638 FLNA/TMSB4X/SYNE1/CAV1/LTBP1/GSN/FBN1/TSPO/PKD2 9 GO:0001954 positive regulation of cell-matrix adhesion 7/504 58/18722 0.000901431122855737 0.0106110611238638 THY1/EFEMP2/RRAS/RIN2/LIMS1/FERMT2/MAP4K4 7 GO:0034340 response to type I interferon 7/504 58/18722 0.000901431122855737 0.0106110611238638 IFITM2/IFI27/IFITM3/IFITM1/JAK1/ISG15/STAT2 7 GO:0016032 viral process 23/504 415/18722 0.000927293498879997 0.0108262428597772 AGTR1/GAS6/AXL/LGALS1/NFIA/IFITM2/IFI27/IFITM3/IFITM1/CD81/ITGB1/CAV1/GSN/CAV2/IFI16/ZFP36/ISG15/JUN/ROCK2/CTBP2/MAN2A1/STOM/KPNA3 23 GO:0038065 collagen-activated signaling pathway 4/504 17/18722 0.000934418481073195 0.0108262428597772 COL1A1/DDR2/COL4A1/COL4A2 4 GO:0045198 establishment of epithelial cell apical/basal polarity 4/504 17/18722 0.000934418481073195 0.0108262428597772 PTK7/FAT1/MSN/MYO9A 4 GO:0061298 retina vasculature development in camera-type eye 4/504 17/18722 0.000934418481073195 0.0108262428597772 PDGFRB/PDGFRA/COL4A1/BMPR2 4 GO:0070593 dendrite self-avoidance 4/504 17/18722 0.000934418481073195 0.0108262428597772 NEXN/PALLD/EXT1/NPTN 4 GO:0052126 movement in host environment 13/504 175/18722 0.000934913085714438 0.0108262428597772 AGTR1/GAS6/AXL/LGALS1/IFITM2/IFITM3/IFITM1/CD81/ITGB1/CAV1/GSN/CAV2/KPNA3 13 GO:0048705 skeletal system morphogenesis 15/504 220/18722 0.000949290189217504 0.0109630188608821 COL1A1/MGP/PDGFRA/COL27A1/MMP2/FGFR1/MEF2C/EXT1/SOX6/SERPINH1/BMP1/CITED2/ARID5B/BMPR2/DHRS3 15 GO:0044344 cellular response to fibroblast growth factor stimulus 10/504 113/18722 0.00095382403991544 0.0109856876618832 COL1A1/THBS1/SULF2/FGFR1/EXT1/SPRY1/ZFP36L1/ZFP36/NR4A1/NPTN 10 GO:0031952 regulation of protein autophosphorylation 6/504 43/18722 0.000966812301727944 0.0110692375102939 ENPP1/RAP2A/CAV1/CALM2/PDGFA/NBN 6 GO:0001738 morphogenesis of a polarized epithelium 9/504 94/18722 0.000968849714217162 0.0110692375102939 CTHRC1/GPC3/ACTB/PTK7/DAAM1/FAT1/MSN/MYO9A/ACTG1 9 GO:1903035 negative regulation of response to wounding 9/504 94/18722 0.000968849714217162 0.0110692375102939 THBS1/WFDC1/PRKG1/PDGFRA/TFPI/MDK/SERPING1/PDGFA/PTEN 9 GO:0043534 blood vessel endothelial cell migration 13/504 176/18722 0.000985348089689792 0.011227713032652 THBS1/FGFR1/MEF2C/ITGB1/TMSB4X/ETS1/ATP2B4/MYH9/HDAC7/HSPB1/STARD13/NR4A1/AKT3 13 GO:0001701 in utero embryonic development 21/504 367/18722 0.00102522139925712 0.0116200823316331 EDNRA/HAND2/PDGFRA/WNT2/NXN/FKBP10/NR2F2/ITGB1/MYH9/IGF2/SH3PXD2A/PKD2/CITED2/ZFP36L1/NOTCH2/CMTM3/MBNL1/SEC24D/MAN2A1/ZMIZ1/NBN 21 GO:1903706 regulation of hemopoiesis 21/504 367/18722 0.00102522139925712 0.0116200823316331 MEIS1/GAS6/AXL/JAG1/MEF2C/MDK/ETS1/SOX4/B2M/FBN1/ZFP36L1/NOTCH2/ZFP36/ISG15/JUN/XBP1/STAT3/PIK3R1/RBFOX2/ZMIZ1/SOS1 21 GO:0010975 regulation of neuron projection development 24/504 445/18722 0.00105319090603728 0.0119055151891463 NR2F1/THY1/MAP1B/SDC2/PMP22/SEMA5A/CHN1/HGF/FLNA/LGALS1/VIM/METRN/LPAR1/RAP2A/PDLIM5/MDK/PTK7/B2M/PLXND1/MAP4K4/MACF1/NPTN/PTEN/BMPR2 24 GO:0001101 response to acid chemical 11/504 135/18722 0.00107400156296442 0.0120788480384364 COL1A2/COL1A1/COL6A1/COL18A1/PDGFRA/COL5A2/COL4A1/MMP2/ATP2B4/PKD2/XBP1 11 GO:0001764 neuron migration 12/504 156/18722 0.00107417792057239 0.0120788480384364 COL3A1/MAP1B/PRKG1/FLNA/GAS6/AXL/NR2F2/FGFR1/MEF2C/MDK/STAT3/ZMIZ1 12 GO:0071902 positive regulation of protein serine/threonine kinase activity 14/504 200/18722 0.00107847025443567 0.0120952845070961 THBS1/PDGFRB/CCND2/FGFR1/ATP2B4/IGF2/PKD2/FERMT2/CALM2/PDGFA/ADAM9/BMPR2/TAOK1/AKAP13 14 GO:0060324 face development 6/504 44/18722 0.00109438995718265 0.0122416970864959 COL1A1/PDGFRA/CRISPLD2/MMP2/RRAS/ARID5B 6 GO:0003073 regulation of systemic arterial blood pressure 9/504 96/18722 0.00112653705828533 0.0125356584636802 AGTR1/RARRES2/CAMK2N1/GAS6/TPM1/ARHGAP42/KCNK6/NR2F2/BMPR2 9 GO:0030510 regulation of BMP signaling pathway 9/504 96/18722 0.00112653705828533 0.0125356584636802 TWSG1/GPC3/FSTL1/FBN1/HIPK2/NOTCH2/HTRA1/BMPR2/CRIM1 9 GO:0030204 chondroitin sulfate metabolic process 5/504 30/18722 0.00113171091759833 0.012560521430903 DCN/BGN/EXT1/DSEL/UGDH 5 GO:0002262 myeloid cell homeostasis 12/504 157/18722 0.00113541680371878 0.0125690051872807 AXL/ETS1/B2M/CITED2/HIPK2/SMAD5/ZFP36L1/ZFP36/KMT2E/ISG15/STAT3/RBFOX2 12 GO:0022407 regulation of cell-cell adhesion 24/504 448/18722 0.00115375605535516 0.0127390171176553 IGFBP2/THY1/PRKG1/LRRC32/LGALS1/PAG1/TWSG1/JAG1/CD81/MDK/MYADM/ETS1/IL6ST/SOX4/TJP1/CAV1/B2M/IGF2/CITED2/JAK1/MYO10/PRKAR1A/XBP1/ZMIZ1 24 GO:0061045 negative regulation of wound healing 8/504 78/18722 0.00117355028506716 0.0128519978692451 THBS1/WFDC1/PRKG1/PDGFRA/TFPI/SERPING1/PDGFA/PTEN 8 GO:0007159 leukocyte cell-cell adhesion 21/504 371/18722 0.00117374310405117 0.0128519978692451 IGFBP2/THY1/LRRC32/LGALS1/PAG1/TWSG1/CD81/ITGB1/MDK/EXT1/ETS1/IL6ST/SOX4/CAV1/CERCAM/B2M/IGF2/PRKAR1A/MSN/XBP1/ZMIZ1 21 GO:0051895 negative regulation of focal adhesion assembly 4/504 18/18722 0.00117601946334539 0.0128519978692451 THBS1/APOD/DLC1/PTEN 4 GO:0150118 negative regulation of cell-substrate junction organization 4/504 18/18722 0.00117601946334539 0.0128519978692451 THBS1/APOD/DLC1/PTEN 4 GO:0010977 negative regulation of neuron projection development 11/504 137/18722 0.00121114757694273 0.0131866826227261 NR2F1/THY1/PMP22/SEMA5A/FLNA/LGALS1/VIM/LPAR1/B2M/MAP4K4/PTEN 11 GO:0070167 regulation of biomineral tissue development 9/504 97/18722 0.00121281681973587 0.0131866826227261 MGP/DDR2/ENPP1/GAS6/MEF2C/SLC8A1/ISG15/ROCK2/BMPR2 9 GO:0010639 negative regulation of organelle organization 20/504 347/18722 0.00122712198704274 0.0133083559660752 MAP1B/LMOD1/PLEKHH2/HGF/DLC1/MYADM/TMSB4X/TJP1/EPS8/SPTBN1/LIMA1/GSN/TSPO/SVIL/PRKAR1A/MAP4/ATRX/PIK3R1/TAOK1/NBN 20 GO:0010038 response to metal ion 21/504 373/18722 0.0012546824890701 0.0135728057615102 SPARC/THBS1/IGFBP2/MT1E/CYBRD1/TXNIP/MEF2C/CRIP1/CAV1/SEC31A/B2M/TSPO/PKD2/CALM2/MAP1LC3A/JUN/MEF2A/ADAM9/PTEN/SLC25A24/SOD3 21 GO:0010720 positive regulation of cell development 18/504 298/18722 0.00125889072758953 0.0135839395934093 MAP1B/SEMA5A/PDE3A/WNT2/FLNA/LIMS2/METRN/MDK/MYADM/IL6ST/LIMS1/PLXND1/TSPO/FERMT2/MACF1/NPTN/MAN2A1/BMPR2 18 GO:0043502 regulation of muscle adaptation 9/504 98/18722 0.00130435287359879 0.0140390423901452 IGFBP5/HAND2/FOXO1/LMCD1/IL6ST/ATP2B4/ROCK2/MEF2A/FBXO32 9 GO:0002063 chondrocyte development 5/504 31/18722 0.00131985029750817 0.0141701515609357 COL27A1/SULF2/EXT1/SERPINH1/BMPR2 5 GO:0003015 heart process 16/504 251/18722 0.00132594186681254 0.014199873676416 GJC1/FXYD1/TBX2/FLNA/TPM1/TGFB2/SLC8A1/EXT1/ATP2B4/CAV1/GSN/SMAD5/CALM2/WWTR1/MEF2A/AKAP13 16 GO:0010951 negative regulation of endopeptidase activity 16/504 252/18722 0.00138168033734422 0.0147523925862853 COL6A3/THBS1/CRYAB/WFDC1/HGF/GAS6/TFPI/TIMP1/A2M/SERPING1/TIMP2/SERPINH1/TIMP3/IFI16/NR4A1/CRIM1 16 GO:0048145 regulation of fibroblast proliferation 8/504 80/18722 0.00138472729109422 0.0147523925862853 PDGFRB/DDR2/PDGFRA/WNT2/GAS6/PDGFA/FOSL2/ZMIZ1 8 GO:0060976 coronary vasculature development 6/504 46/18722 0.00138789183704346 0.0147523925862853 PDGFRB/HAND2/MYOCD/GPC3/PTK7/PLXND1 6 GO:0010717 regulation of epithelial to mesenchymal transition 9/504 99/18722 0.00140137630680752 0.0148219825717538 COL1A1/TGFB1I1/TGFB2/JAG1/MDK/SPRY1/FERMT2/WWTR1/PTEN 9 GO:0110149 regulation of biomineralization 9/504 99/18722 0.00140137630680752 0.0148219825717538 MGP/DDR2/ENPP1/GAS6/MEF2C/SLC8A1/ISG15/ROCK2/BMPR2 9 GO:0045861 negative regulation of proteolysis 20/504 351/18722 0.00140751078634381 0.0148501076297459 COL6A3/THBS1/CRYAB/WFDC1/CAMK2N1/HGF/GAS6/TFPI/TIMP1/A2M/GAS1/GPC3/SERPING1/TIMP2/SERPINH1/TIMP3/HIPK2/IFI16/NR4A1/CRIM1 20 GO:0009743 response to carbohydrate 16/504 253/18722 0.00143938067307609 0.0151117287863738 SPARC/COL6A2/THBS1/MAP1B/CAMK2N1/GAS6/LGALS1/TXNIP/SLC8A1/SOX4/EGR1/ZFP36L1/MAP4K4/XBP1/PTEN/RAB11FIP2 16 GO:0060828 regulation of canonical Wnt signaling pathway 16/504 253/18722 0.00143938067307609 0.0151117287863738 COL1A1/IGFBP2/IGFBP4/SEMA5A/ADGRA2/CTHRC1/ZEB2/SULF2/GPC3/MDK/SOX4/CAV1/EGR1/PTK7/RBMS3/WWTR1 16 GO:0045019 negative regulation of nitric oxide biosynthetic process 4/504 19/18722 0.00145819039670401 0.0152343461249786 ATP2B4/CAV1/TSPO/ROCK2 4 GO:1904406 negative regulation of nitric oxide metabolic process 4/504 19/18722 0.00145819039670401 0.0152343461249786 ATP2B4/CAV1/TSPO/ROCK2 4 GO:0032233 positive regulation of actin filament bundle assembly 7/504 63/18722 0.00147825688935925 0.0154063211908099 SYNPO2/FLNA/TPM1/LPAR1/SORBS3/FERMT2/ROCK2 7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 8/504 81/18722 0.00150106723865152 0.0155681075503833 TGFB1I1/EMILIN1/CAV1/SPRY1/LTBP1/FBN1/CAV2/HTRA1 8 GO:0048144 fibroblast proliferation 8/504 81/18722 0.00150106723865152 0.0155681075503833 PDGFRB/DDR2/PDGFRA/WNT2/GAS6/PDGFA/FOSL2/ZMIZ1 8 GO:0071774 response to fibroblast growth factor 10/504 120/18722 0.00150978968637707 0.0156206569730974 COL1A1/THBS1/SULF2/FGFR1/EXT1/SPRY1/ZFP36L1/ZFP36/NR4A1/NPTN 10 GO:0051346 negative regulation of hydrolase activity 21/504 379/18722 0.00152681261349819 0.0157165791838994 COL6A3/THBS1/CRYAB/WFDC1/HGF/GAS6/TFPI/TIMP1/TGFB2/A2M/GPC3/SERPING1/TIMP2/SPRY1/SERPINH1/TIMP3/IFI16/CNN3/ROCK2/NR4A1/CRIM1 21 GO:0003180 aortic valve morphogenesis 5/504 32/18722 0.00153009523531527 0.0157165791838994 SLIT3/ELN/EMILIN1/JAG1/ROCK2 5 GO:1901889 negative regulation of cell junction assembly 5/504 32/18722 0.00153009523531527 0.0157165791838994 THBS1/APOD/DLC1/ROCK2/PTEN 5 GO:0010761 fibroblast migration 6/504 47/18722 0.00155541613092871 0.0158245074463295 THBS1/AKAP12/DDR2/ITGB1/SLC8A1/ARID5B 6 GO:0045747 positive regulation of Notch signaling pathway 6/504 47/18722 0.00155541613092871 0.0158245074463295 TGFB2/JAG1/IL6ST/EPN2/STAT3/ZMIZ1 6 GO:0101023 vascular endothelial cell proliferation 6/504 47/18722 0.00155541613092871 0.0158245074463295 FGFR1/MEF2C/MDK/IGF2/STAT3/AKT3 6 GO:1905562 regulation of vascular endothelial cell proliferation 6/504 47/18722 0.00155541613092871 0.0158245074463295 FGFR1/MEF2C/MDK/IGF2/STAT3/AKT3 6 GO:0030837 negative regulation of actin filament polymerization 7/504 64/18722 0.00162204703845398 0.0164631995138096 LMOD1/MYADM/TMSB4X/EPS8/SPTBN1/GSN/SVIL 7 GO:0071214 cellular response to abiotic stimulus 19/504 331/18722 0.00168632791754628 0.0170347025807926 COL1A1/MYLK/CRYAB/TIMP1/CCND2/MMP2/CRIP1/SLC38A2/EGR1/CNN2/TSPO/PKD2/ZFP36L1/IFI16/RHOB/CLOCK/POLK/PIK3R1/PTEN 19 GO:0104004 cellular response to environmental stimulus 19/504 331/18722 0.00168632791754628 0.0170347025807926 COL1A1/MYLK/CRYAB/TIMP1/CCND2/MMP2/CRIP1/SLC38A2/EGR1/CNN2/TSPO/PKD2/ZFP36L1/IFI16/RHOB/CLOCK/POLK/PIK3R1/PTEN 19 GO:0045637 regulation of myeloid cell differentiation 14/504 210/18722 0.0017137217377258 0.017270596663449 MEIS1/JAG1/MEF2C/ETS1/B2M/FBN1/ZFP36L1/NOTCH2/ZFP36/ISG15/JUN/STAT3/PIK3R1/RBFOX2 14 GO:1903053 regulation of extracellular matrix organization 6/504 48/18722 0.00173788465547484 0.0174318805935305 AEBP1/ANTXR1/DDR2/EFEMP2/EMILIN1/ETS1 6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 6/504 48/18722 0.00173788465547484 0.0174318805935305 THBS1/CAV1/TIMP3/ATF3/PTEN/PEA15 6 GO:0070570 regulation of neuron projection regeneration 5/504 33/18722 0.00176395998582503 0.017610750045398 THY1/HGF/FLNA/MAP4K4/PTEN 5 GO:0150117 positive regulation of cell-substrate junction organization 5/504 33/18722 0.00176395998582503 0.017610750045398 THY1/LIMS1/FERMT2/MAP4K4/PIK3R1 5 GO:0003215 cardiac right ventricle morphogenesis 4/504 20/18722 0.00178431051279037 0.0176899276592883 HAND2/TGFB2/JAG1/SOX4 4 GO:0061318 renal filtration cell differentiation 4/504 20/18722 0.00178431051279037 0.0176899276592883 JAG1/EXT1/LAMB2/NOTCH2 4 GO:0072112 glomerular visceral epithelial cell differentiation 4/504 20/18722 0.00178431051279037 0.0176899276592883 JAG1/EXT1/LAMB2/NOTCH2 4 GO:1901653 cellular response to peptide 20/504 359/18722 0.00183684936261054 0.0181686512185992 MAP1B/AGTR1/RARRES2/ENPP1/VIM/FOXO1/CAV1/RHOQ/IGF2/FBN1/CAV2/ZFP36L1/ROCK2/XBP1/STAT3/PIK3R1/NR4A1/PTEN/PTPRA/EIF4EBP2 20 GO:0022409 positive regulation of cell-cell adhesion 17/504 284/18722 0.00187004398316654 0.0184542677599783 IGFBP2/THY1/LGALS1/CD81/MDK/ETS1/IL6ST/SOX4/TJP1/CAV1/B2M/IGF2/CITED2/JAK1/MYO10/XBP1/ZMIZ1 17 GO:0010921 regulation of phosphatase activity 8/504 84/18722 0.00189717997715367 0.0186359771089141 ITGA1/PDGFRB/TGFB2/MEF2C/CALM2/HSP90B1/ROCK2/PPP1R12A 8 GO:0042310 vasoconstriction 8/504 84/18722 0.00189717997715367 0.0186359771089141 ACTA2/AGTR1/EDNRA/ARHGAP42/SLC8A1/EDNRB/CAV1/BMPR2 8 GO:0031960 response to corticosteroid 12/504 167/18722 0.00192321220374587 0.0187174660044504 COL1A1/IGFBP7/SPARC/IGFBP2/SLIT3/FOXO1/MDK/NR3C1/ZFP36L1/ZFP36/ADAM9/FBXO32 12 GO:0030195 negative regulation of blood coagulation 6/504 49/18722 0.00193613853825581 0.0187174660044504 THBS1/PRKG1/PDGFRA/TFPI/SERPING1/PDGFA 6 GO:0046580 negative regulation of Ras protein signal transduction 6/504 49/18722 0.00193613853825581 0.0187174660044504 DLC1/TGFB2/ARHGAP42/ITGB1/TIMP2/SPRY1 6 GO:0052372 modulation by symbiont of entry into host 6/504 49/18722 0.00193613853825581 0.0187174660044504 LGALS1/IFITM2/IFITM3/IFITM1/CAV1/GSN 6 GO:0060964 regulation of gene silencing by miRNA 6/504 49/18722 0.00193613853825581 0.0187174660044504 MYOCD/KCNQ1OT1/NCOR2/ZFP36/STAT3/TNRC6B 6 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 6/504 49/18722 0.00193613853825581 0.0187174660044504 THBS1/HGF/TIMP3/ATF3/PTEN/PEA15 6 GO:1904752 regulation of vascular associated smooth muscle cell migration 6/504 49/18722 0.00193613853825581 0.0187174660044504 IGFBP5/PRKG1/MYOCD/TPM1/MEF2C/ADAMTS1 6 GO:0030193 regulation of blood coagulation 7/504 66/18722 0.00194209736877 0.0187326908730344 THBS1/PRKG1/PDGFRA/TFPI/SERPING1/CAV1/PDGFA 7 GO:0060326 cell chemotaxis 18/504 310/18722 0.00194866224668595 0.0187536796848853 ITGA1/THBS1/PDGFRB/AGTR1/RARRES2/SEMA5A/PDGFRA/HGF/GAS6/TGFB2/LPAR1/FGFR1/MDK/EDNRB/TMSB4X/HSPB1/PARVA/NR4A1 18 GO:0001558 regulation of cell growth 22/504 414/18722 0.00201562159096465 0.0192520674921633 IGFBP7/IGFBP5/MEG3/IGFBP4/CRYAB/MAP1B/WFDC1/SLIT3/AGTR1/SEMA5A/MYOCD/FHL1/ENPP1/LTBP4/FBLN5/TGFB2/RERG/CCDC85B/DPYSL2/MACF1/BMPR2/DCBLD2 22 GO:0007043 cell-cell junction assembly 11/504 146/18722 0.00201856248721618 0.0192520674921633 GJC1/CDH11/MTDH/VCL/ACTB/TJP1/CAV1/HDAC7/TLN1/ROCK2/ACTG1 11 GO:0021932 hindbrain radial glia guided cell migration 3/504 10/18722 0.00202069621568917 0.0192520674921633 FLNA/ITGB1/RBFOX2 3 GO:0072203 cell proliferation involved in metanephros development 3/504 10/18722 0.00202069621568917 0.0192520674921633 PDGFRB/GPC3/EGR1 3 GO:0010922 positive regulation of phosphatase activity 5/504 34/18722 0.00202297643435088 0.0192520674921633 ITGA1/PDGFRB/MEF2C/CALM2/PPP1R12A 5 GO:0045936 negative regulation of phosphate metabolic process 23/504 441/18722 0.00204622575110303 0.0194300502988072 THY1/MYOCD/EMILIN1/ENPP1/CAMK2N1/HGF/TGFB2/IGFBP3/NR2F2/SLC8A1/MYADM/PKIG/CAV1/SPRY1/CALM2/HSPB1/PRKAR1A/PDGFA/AIDA/WWTR1/ROCK2/STAT3/PTEN 23 GO:0010563 negative regulation of phosphorus metabolic process 23/504 442/18722 0.00210583513816969 0.0199517373512175 THY1/MYOCD/EMILIN1/ENPP1/CAMK2N1/HGF/TGFB2/IGFBP3/NR2F2/SLC8A1/MYADM/PKIG/CAV1/SPRY1/CALM2/HSPB1/PRKAR1A/PDGFA/AIDA/WWTR1/ROCK2/STAT3/PTEN 23 GO:0035914 skeletal muscle cell differentiation 7/504 67/18722 0.00211941717273441 0.0199998993985686 MYOCD/MEF2C/EGR1/CITED2/DDX17/ATF3/NR4A1 7 GO:0006937 regulation of muscle contraction 12/504 169/18722 0.00212492165574042 0.0199998993985686 MYL9/HSPB6/CNN1/PRKG1/MYOCD/TPM1/ARHGAP42/PPP1R12B/SLC8A1/CAV1/CALM2/NR4A1 12 GO:0060041 retina development in camera-type eye 11/504 147/18722 0.00213035853854988 0.0199998993985686 PDGFRB/THY1/LAMC3/PDGFRA/COL4A1/TGFB2/ATP2B4/LAMB2/HIPK2/MAN2A1/BMPR2 11 GO:1900047 negative regulation of hemostasis 6/504 50/18722 0.00215103310120968 0.0199998993985686 THBS1/PRKG1/PDGFRA/TFPI/SERPING1/PDGFA 6 GO:1904738 vascular associated smooth muscle cell migration 6/504 50/18722 0.00215103310120968 0.0199998993985686 IGFBP5/PRKG1/MYOCD/TPM1/MEF2C/ADAMTS1 6 GO:0051403 stress-activated MAPK cascade 15/504 239/18722 0.00215470925197332 0.0199998993985686 CRYAB/HAND2/HGF/TGFB2/FOXO1/RAP2A/ARHGEF6/HIPK2/ZFP36L1/MAP4K4/ZFP36/ZMYND11/AIDA/PJA2/TAOK1 15 GO:0003177 pulmonary valve development 4/504 21/18722 0.00215772375912477 0.0199998993985686 TGFB2/JAG1/NOTCH2/BMPR2 4 GO:0032516 positive regulation of phosphoprotein phosphatase activity 4/504 21/18722 0.00215772375912477 0.0199998993985686 ITGA1/PDGFRB/CALM2/PPP1R12A 4 GO:0046597 negative regulation of viral entry into host cell 4/504 21/18722 0.00215772375912477 0.0199998993985686 IFITM2/IFITM3/IFITM1/GSN 4 GO:0072311 glomerular epithelial cell differentiation 4/504 21/18722 0.00215772375912477 0.0199998993985686 JAG1/EXT1/LAMB2/NOTCH2 4 GO:0014074 response to purine-containing compound 11/504 148/18722 0.00224713111822068 0.0207386420478552 COL1A1/IGFBP5/SPARC/PDE3A/SLC8A1/PKD2/ZFP36L1/HSP90B1/JUN/PTEN/AHR 11 GO:0051384 response to glucocorticoid 11/504 148/18722 0.00224713111822068 0.0207386420478552 IGFBP7/SPARC/IGFBP2/SLIT3/FOXO1/MDK/NR3C1/ZFP36L1/ZFP36/ADAM9/FBXO32 11 GO:0090263 positive regulation of canonical Wnt signaling pathway 9/504 106/18722 0.0022547285379378 0.0207639117297591 COL1A1/SEMA5A/ADGRA2/ZEB2/SULF2/GPC3/SOX4/CAV1/PTK7 9 GO:0019221 cytokine-mediated signaling pathway 24/504 472/18722 0.00230136685666759 0.0210818636402516 PXDN/SLIT3/GAS6/AXL/OSMR/IFITM2/IFI27/IFITM3/IFITM1/EXT1/IL1R1/TMSB4X/IL6ST/CAV1/EGR1/LIMS1/ACTN4/JAK1/PLP2/ISG15/STAT3/STAT2/LIFR/SOS1 24 GO:0030048 actin filament-based movement 10/504 127/18722 0.00230403445870939 0.0210818636402516 GJC1/MYO1B/FLNA/TPM1/MYL6/MYH9/CAV1/ACTN4/GSN/PARVA 10 GO:0050654 chondroitin sulfate proteoglycan metabolic process 5/504 35/18722 0.00230869009408984 0.0210818636402516 DCN/BGN/EXT1/DSEL/UGDH 5 GO:1900046 regulation of hemostasis 7/504 68/18722 0.00230898951173361 0.0210818636402516 THBS1/PRKG1/PDGFRA/TFPI/SERPING1/CAV1/PDGFA 7 GO:0051592 response to calcium ion 11/504 149/18722 0.00236904144866861 0.0215840386144157 SPARC/THBS1/TXNIP/MEF2C/CAV1/SEC31A/PKD2/CALM2/MEF2A/ADAM9/SLC25A24 11 GO:0060043 regulation of cardiac muscle cell proliferation 6/504 51/18722 0.00238343656850018 0.0216689882068112 TBX2/WNT2/MEIS1/MEF2C/CITED2/PTEN 6 GO:0001933 negative regulation of protein phosphorylation 19/504 342/18722 0.00243695073515631 0.022108472380728 THY1/MYOCD/EMILIN1/ENPP1/CAMK2N1/HGF/IGFBP3/NR2F2/SLC8A1/MYADM/PKIG/CAV1/SPRY1/CALM2/HSPB1/PRKAR1A/AIDA/WWTR1/PTEN 19 GO:0010611 regulation of cardiac muscle hypertrophy 7/504 69/18722 0.00251136798389922 0.0227353292271215 HAND2/FOXO1/LMCD1/IL6ST/ATP2B4/ROCK2/MEF2A 7 GO:0034764 positive regulation of transmembrane transport 14/504 219/18722 0.00252628690344831 0.022822037924809 THY1/FXYD1/FLNA/GPC3/ITGB1/HSPA2/TMSB4X/RHOQ/ACTN4/PKD2/CALM2/VMP1/MEF2A/PIK3R1 14 GO:0035089 establishment of apical/basal cell polarity 4/504 22/18722 0.00258172480608952 0.0232246528345695 PTK7/FAT1/MSN/MYO9A 4 GO:0055093 response to hyperoxia 4/504 22/18722 0.00258172480608952 0.0232246528345695 COL1A1/PDGFRB/FOXO1/CAV1 4 GO:0010762 regulation of fibroblast migration 5/504 36/18722 0.00262265616247381 0.023543297861871 THBS1/AKAP12/DDR2/ITGB1/SLC8A1 5 GO:0031103 axon regeneration 6/504 52/18722 0.00263422875117431 0.0235482415350791 MAP1B/APOD/FLNA/LAMB2/TSPO/PTEN 6 GO:0060147 regulation of posttranscriptional gene silencing 6/504 52/18722 0.00263422875117431 0.0235482415350791 MYOCD/KCNQ1OT1/NCOR2/ZFP36/STAT3/TNRC6B 6 GO:0045123 cellular extravasation 7/504 70/18722 0.00272711477155928 0.0242855056001331 ITGA1/THY1/ITGB1/MDK/EXT1/IL1R1/CD99 7 GO:0072009 nephron epithelium development 9/504 109/18722 0.00272806990125529 0.0242855056001331 JAG1/GPC3/MEF2C/EXT1/LAMB2/PKD2/NOTCH2/WWTR1/PBX1 9 GO:0050819 negative regulation of coagulation 6/504 53/18722 0.00290429971296855 0.0257470387417316 THBS1/PRKG1/PDGFRA/TFPI/SERPING1/PDGFA 6 GO:0060966 regulation of gene silencing by RNA 6/504 53/18722 0.00290429971296855 0.0257470387417316 MYOCD/KCNQ1OT1/NCOR2/ZFP36/STAT3/TNRC6B 6 GO:0048568 embryonic organ development 22/504 427/18722 0.00293845643387138 0.0259959096106261 RARRES2/CTHRC1/TBX2/HAND2/PDGFRA/WNT2/TGFB2/NR2F2/MEF2C/TSHZ1/PTK7/TEAD1/IGF2/FBN1/PKD2/CITED2/HIPK2/ZFP36L1/NOTCH2/PDGFA/PBX1/KMT2A 22 GO:0031098 stress-activated protein kinase signaling cascade 15/504 247/18722 0.00295061515759818 0.0259967218473463 CRYAB/HAND2/HGF/TGFB2/FOXO1/RAP2A/ARHGEF6/HIPK2/ZFP36L1/MAP4K4/ZFP36/ZMYND11/AIDA/PJA2/TAOK1 15 GO:0033555 multicellular organismal response to stress 7/504 71/18722 0.00295680009777915 0.0259967218473463 THBS1/MEF2C/MDK/EXT1/EDNRB/TSPO/PTEN 7 GO:0050818 regulation of coagulation 7/504 71/18722 0.00295680009777915 0.0259967218473463 THBS1/PRKG1/PDGFRA/TFPI/SERPING1/CAV1/PDGFA 7 GO:0032570 response to progesterone 5/504 37/18722 0.00296643564959849 0.0260278840466824 THBS1/TGFB2/TXNIP/CAV1/TSPO 5 GO:0003283 atrial septum development 4/504 23/18722 0.00305954641938725 0.0267898398566429 TGFB2/SOX4/NOTCH2/BMPR2 4 GO:0048511 rhythmic process 17/504 298/18722 0.00308090378945006 0.0269216807613908 SLIT3/PDGFRA/AXL/ID4/TGFB2/MDK/ETS1/EGR1/NCOR2/ZFHX3/ADAMTS1/CLOCK/JUN/ROCK2/PTEN/KMT2A/AHR 17 GO:0032984 protein-containing complex disassembly 14/504 224/18722 0.00310026748409078 0.0270355978765712 MAP1B/LMOD1/SEMA5A/PLEKHH2/EPS8/SPTBN1/LIMA1/GSN/DSTN/CFL2/VMP1/SVIL/MAP1LC3A/TAOK1 14 GO:0071453 cellular response to oxygen levels 12/504 177/18722 0.00311221731428608 0.0270845307208644 COX4I2/FOXO1/SLC8A1/MALAT1/CAV1/EGR1/CITED2/HIPK2/ZFP36L1/EIF4EBP1/ROCK2/PTEN 12 GO:0014033 neural crest cell differentiation 8/504 91/18722 0.00314285773487635 0.0272955916689566 SEMA5A/EDNRA/HAND2/JAG1/MEF2C/EXT1/EDNRB/CITED2 8 GO:0060350 endochondral bone morphogenesis 6/504 54/18722 0.00319454842147646 0.0276320810629866 COL1A1/COL27A1/MEF2C/EXT1/SERPINH1/BMPR2 6 GO:0043903 regulation of biological process involved in symbiotic interaction 7/504 72/18722 0.00320100166772253 0.0276320810629866 LGALS1/IFITM2/IFITM3/IFITM1/CAV1/GSN/CAV2 7 GO:0051057 positive regulation of small GTPase mediated signal transduction 7/504 72/18722 0.00320100166772253 0.0276320810629866 COL3A1/PDGFRB/LPAR1/NOTCH2/MAP4K4/AKAP13/SOS1 7 GO:0034284 response to monosaccharide 14/504 225/18722 0.00322698615794861 0.0278002255099081 SPARC/COL6A2/THBS1/CAMK2N1/GAS6/LGALS1/TXNIP/SLC8A1/SOX4/EGR1/MAP4K4/XBP1/PTEN/RAB11FIP2 14 GO:0052548 regulation of endopeptidase activity 22/504 432/18722 0.00337761514260224 0.0290393350187915 COL6A3/THBS1/CRYAB/WFDC1/HGF/GAS6/TFPI/TIMP1/DLC1/A2M/UACA/HIP1/SERPING1/TIMP2/SERPINH1/TIMP3/GSN/IFI16/ROCK2/STAT3/NR4A1/CRIM1 22 GO:0042063 gliogenesis 17/504 301/18722 0.00341095044211578 0.0292670506810456 LAMA2/LAMC3/MXRA8/TGFB2/VIM/METRN/MDK/NFIB/IL6ST/SOX4/SOX6/LAMB2/TSPO/LAMB1/STAT3/PTEN/ZMIZ1 17 GO:0010959 regulation of metal ion transport 21/504 406/18722 0.00345954505621154 0.0295717588056265 MYLK/PDGFRB/THY1/FXYD1/FHL1/FLNA/SLMAP/ITGB1/SLC8A1/HSPA2/ATP2B4/CAV1/B2M/ACTN4/TSPO/PKD2/CALM2/VMP1/AHNAK/PTEN/STOM 21 GO:0051145 smooth muscle cell differentiation 7/504 73/18722 0.00346030409614165 0.0295717588056265 TBX2/MYOCD/EFEMP2/SGCB/MEF2C/EDNRB/EPC1 7 GO:0051701 biological process involved in interaction with host 13/504 203/18722 0.00349303518457952 0.0297725585656577 AGTR1/GAS6/AXL/LGALS1/IFITM2/IFITM3/IFITM1/CD81/ITGB1/CAV1/GSN/CAV2/KPNA3 13 GO:1905517 macrophage migration 6/504 55/18722 0.00350588138874314 0.0297725585656577 THBS1/RARRES2/EMILIN1/CD81/MDK/EDNRB 6 GO:0060009 Sertoli cell development 3/504 12/18722 0.00355884523271851 0.0297725585656577 FLNA/FNDC3A/ATRX 3 GO:0061307 cardiac neural crest cell differentiation involved in heart development 3/504 12/18722 0.00355884523271851 0.0297725585656577 HAND2/JAG1/CITED2 3 GO:0061308 cardiac neural crest cell development involved in heart development 3/504 12/18722 0.00355884523271851 0.0297725585656577 HAND2/JAG1/CITED2 3 GO:0072015 glomerular visceral epithelial cell development 3/504 12/18722 0.00355884523271851 0.0297725585656577 JAG1/LAMB2/NOTCH2 3 GO:0098974 postsynaptic actin cytoskeleton organization 3/504 12/18722 0.00355884523271851 0.0297725585656577 FARP1/ACTB/ACTG1 3 GO:0030111 regulation of Wnt signaling pathway 18/504 328/18722 0.00356216184352002 0.0297725585656577 COL1A1/IGFBP2/IGFBP4/SEMA5A/ADGRA2/CTHRC1/NXN/ZEB2/SULF2/GPC3/MDK/SOX4/CAV1/EGR1/PTK7/RBMS3/WWTR1/MACF1 18 GO:0003148 outflow tract septum morphogenesis 4/504 24/18722 0.00359434811313912 0.0297725585656577 TBX2/TGFB2/PARVA/BMPR2 4 GO:0003181 atrioventricular valve morphogenesis 4/504 24/18722 0.00359434811313912 0.0297725585656577 SLIT3/TGFB2/SOX4/BMPR2 4 GO:0030859 polarized epithelial cell differentiation 4/504 24/18722 0.00359434811313912 0.0297725585656577 PTK7/FAT1/MSN/MYO9A 4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 4/504 24/18722 0.00359434811313912 0.0297725585656577 IGFBP5/IGFBP2/IGFBP4/IGFBP3 4 GO:0051043 regulation of membrane protein ectodomain proteolysis 4/504 24/18722 0.00359434811313912 0.0297725585656577 TIMP1/TIMP2/TIMP3/ADAM9 4 GO:0072010 glomerular epithelium development 4/504 24/18722 0.00359434811313912 0.0297725585656577 JAG1/EXT1/LAMB2/NOTCH2 4 GO:0051591 response to cAMP 8/504 93/18722 0.00359528205473423 0.0297725585656577 COL1A1/IGFBP5/SPARC/SLC8A1/PKD2/ZFP36L1/JUN/AHR 8 GO:0060349 bone morphogenesis 8/504 93/18722 0.00359528205473423 0.0297725585656577 COL1A1/COL27A1/MEF2C/EXT1/SERPINH1/CITED2/BMPR2/DHRS3 8 GO:0071383 cellular response to steroid hormone stimulus 13/504 204/18722 0.0036420630329085 0.030101615743942 PLPP1/KANK2/TFPI/FOXO1/NR3C1/ZFP36L1/NCOR2/ZFP36/DDX17/CLOCK/FBXO32/RBFOX2/ZMIZ1 13 GO:0022898 regulation of transmembrane transporter activity 16/504 278/18722 0.00369489180323182 0.0304792908787829 FXYD1/FHL1/SLMAP/MEF2C/ITGB1/HSPA2/TMSB4X/ACTB/CAV1/ACTN4/PKD2/CALM2/VMP1/AHNAK/PTEN/STOM 16 GO:0010463 mesenchymal cell proliferation 5/504 39/18722 0.00374968535059067 0.0308716869038033 HAND2/WNT2/GPC3/NFIB/PDGFA 5 GO:0070371 ERK1 and ERK2 cascade 18/504 330/18722 0.00379542563940522 0.0311881803022663 PLA2G2A/PDGFRB/AKAP12/HAND2/PDGFRA/EMILIN1/CAMK2N1/GAS6/RRAS/SPRY1/TIMP3/FERMT2/ZFP36L1/NOTCH2/PDGFA/ATF3/NPTN/PTEN 18 GO:0010518 positive regulation of phospholipase activity 6/504 56/18722 0.00383921130519973 0.0313103368994732 PDGFRB/AGTR1/EDNRA/PDGFRA/LPAR1/FGFR1 6 GO:0051058 negative regulation of small GTPase mediated signal transduction 6/504 56/18722 0.00383921130519973 0.0313103368994732 DLC1/TGFB2/ARHGAP42/ITGB1/TIMP2/SPRY1 6 GO:0061326 renal tubule development 8/504 94/18722 0.00383960134222419 0.0313103368994732 COL4A1/JAG1/GPC3/MEF2C/PKD2/NOTCH2/WWTR1/PBX1 8 GO:1902414 protein localization to cell junction 8/504 94/18722 0.00383960134222419 0.0313103368994732 FLNA/VCL/ACTB/TJP1/FERMT2/JAK1/HSPB1/ACTG1 8 GO:1904062 regulation of cation transmembrane transport 19/504 357/18722 0.00389668439228307 0.0316688445099587 THY1/FXYD1/FHL1/FLNA/SLMAP/MEF2C/ITGB1/SLC8A1/HSPA2/TMSB4X/ATP2B4/CAV1/ACTN4/PKD2/CALM2/VMP1/AHNAK/PTEN/STOM 19 GO:0061138 morphogenesis of a branching epithelium 12/504 182/18722 0.00389838806745571 0.0316688445099587 EDNRA/WNT2/HGF/COL4A1/GPC3/MDK/EXT1/SPRY1/PLXND1/PKD2/PDGFA/PBX1 12 GO:0042326 negative regulation of phosphorylation 20/504 385/18722 0.00407230692520075 0.0330189136458877 THY1/MYOCD/EMILIN1/ENPP1/CAMK2N1/HGF/IGFBP3/NR2F2/SLC8A1/MYADM/PKIG/CAV1/SPRY1/CALM2/HSPB1/PRKAR1A/AIDA/WWTR1/STAT3/PTEN 20 GO:0045666 positive regulation of neuron differentiation 8/504 95/18722 0.00409654969345925 0.0331525697730139 MAP1B/ZEB1/TCF4/FGFR1/MEF2C/TIMP2/PTEN/TCF12 8 GO:0008286 insulin receptor signaling pathway 9/504 116/18722 0.00413949759318982 0.0332835893632442 RARRES2/ENPP1/FOXO1/RHOQ/IGF2/CAV2/PIK3R1/PTPRA/EIF4EBP2 9 GO:0030318 melanocyte differentiation 4/504 25/18722 0.00418920600308283 0.0332835893632442 ENPP1/ZEB2/MEF2C/EDNRB 4 GO:0031579 membrane raft organization 4/504 25/18722 0.00418920600308283 0.0332835893632442 MYADM/CAV1/GSN/CAV2 4 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 4/504 25/18722 0.00418920600308283 0.0332835893632442 GJC1/SLC8A1/CAV1/CALM2 4 GO:1903901 negative regulation of viral life cycle 4/504 25/18722 0.00418920600308283 0.0332835893632442 IFITM2/IFITM3/IFITM1/GSN 4 GO:1904753 negative regulation of vascular associated smooth muscle cell migration 4/504 25/18722 0.00418920600308283 0.0332835893632442 PRKG1/MYOCD/TPM1/MEF2C 4 GO:0010863 positive regulation of phospholipase C activity 5/504 40/18722 0.0041922730361151 0.0332835893632442 PDGFRB/EDNRA/PDGFRA/LPAR1/FGFR1 5 GO:0060412 ventricular septum morphogenesis 5/504 40/18722 0.0041922730361151 0.0332835893632442 SLIT3/TGFB2/SOX4/CITED2/BMPR2 5 GO:0072210 metanephric nephron development 5/504 40/18722 0.0041922730361151 0.0332835893632442 PDGFRB/PDGFRA/EGR1/LAMB2/PKD2 5 GO:0035107 appendage morphogenesis 10/504 138/18722 0.00419842140575441 0.0332835893632442 TBX2/HAND2/TGFB2/GPC3/EXT1/SOX4/NOTCH2/MBNL1/ATRX/PBX1 10 GO:0035108 limb morphogenesis 10/504 138/18722 0.00419842140575441 0.0332835893632442 TBX2/HAND2/TGFB2/GPC3/EXT1/SOX4/NOTCH2/MBNL1/ATRX/PBX1 10 GO:0006809 nitric oxide biosynthetic process 7/504 76/18722 0.00433475395954265 0.0342373450445947 ATP2B4/CAV1/TSPO/DDAH2/PKD2/CYB5R3/ROCK2 7 GO:0043536 positive regulation of blood vessel endothelial cell migration 7/504 76/18722 0.00433475395954265 0.0342373450445947 THBS1/FGFR1/TMSB4X/ETS1/HDAC7/HSPB1/AKT3 7 GO:1901655 cellular response to ketone 8/504 96/18722 0.00436655084211143 0.0343614581000776 GAS6/ADCY3/FOXO1/NR3C1/ROCK2/MSN/FBXO32/AHR 8 GO:1904035 regulation of epithelial cell apoptotic process 8/504 96/18722 0.00436655084211143 0.0343614581000776 THBS1/CD248/SEMA5A/GAS6/MDK/GSN/ZFP36L1/ZFP36 8 GO:0014902 myotube differentiation 9/504 117/18722 0.00438062705356415 0.0344088591909552 ADAMTS5/EHD2/MYOCD/MEF2C/CD81/MYH9/ADAM12/CAV2/XBP1 9 GO:0070372 regulation of ERK1 and ERK2 cascade 17/504 309/18722 0.00443660231694178 0.0347845902757656 PLA2G2A/PDGFRB/AKAP12/HAND2/PDGFRA/EMILIN1/CAMK2N1/GAS6/RRAS/SPRY1/TIMP3/FERMT2/NOTCH2/PDGFA/ATF3/NPTN/PTEN 17 GO:0014745 negative regulation of muscle adaptation 3/504 13/18722 0.00453475768403728 0.0351670046894579 IGFBP5/FOXO1/ATP2B4 3 GO:0030836 positive regulation of actin filament depolymerization 3/504 13/18722 0.00453475768403728 0.0351670046894579 SEMA5A/DSTN/CFL2 3 GO:0034112 positive regulation of homotypic cell-cell adhesion 3/504 13/18722 0.00453475768403728 0.0351670046894579 LGALS1/IL6ST/JAK1 3 GO:0036462 TRAIL-activated apoptotic signaling pathway 3/504 13/18722 0.00453475768403728 0.0351670046894579 TIMP3/ATF3/PTEN 3 GO:0072310 glomerular epithelial cell development 3/504 13/18722 0.00453475768403728 0.0351670046894579 JAG1/LAMB2/NOTCH2 3 GO:0072672 neutrophil extravasation 3/504 13/18722 0.00453475768403728 0.0351670046894579 MDK/IL1R1/CD99 3 GO:0043666 regulation of phosphoprotein phosphatase activity 6/504 58/18722 0.00457553542621398 0.0353967731259781 ITGA1/PDGFRB/CALM2/HSP90B1/ROCK2/PPP1R12A 6 GO:0032409 regulation of transporter activity 17/504 310/18722 0.00458095378859487 0.0353967731259781 FXYD1/FHL1/SLMAP/MEF2C/ITGB1/HSPA2/TMSB4X/ACTB/CAV1/ACTN4/PKD2/CALM2/VMP1/AHNAK/PTEN/STOM/KMT2A 17 GO:0031345 negative regulation of cell projection organization 12/504 186/18722 0.00463609036752212 0.035577119964548 NR2F1/THY1/PMP22/SEMA5A/FLNA/LGALS1/VIM/LPAR1/B2M/MAP4K4/MAP4/PTEN 12 GO:0030177 positive regulation of Wnt signaling pathway 10/504 140/18722 0.00464708821010185 0.035577119964548 COL1A1/SEMA5A/ADGRA2/ZEB2/SULF2/GPC3/SOX4/CAV1/PTK7/MACF1 10 GO:0031333 negative regulation of protein-containing complex assembly 10/504 140/18722 0.00464708821010185 0.035577119964548 CRYAB/LMOD1/MYADM/TMSB4X/EPS8/SPTBN1/GSN/SVIL/EIF4EBP1/AIDA 10 GO:0010827 regulation of glucose transmembrane transport 7/504 77/18722 0.00466042345618373 0.035577119964548 EDNRA/ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 7 GO:0048286 lung alveolus development 5/504 41/18722 0.00467090201266356 0.035577119964548 IGFBP5/MYOCD/PDGFA/MAN2A1/BMPR2 5 GO:0051693 actin filament capping 5/504 41/18722 0.00467090201266356 0.035577119964548 LMOD1/EPS8/SPTBN1/GSN/SVIL 5 GO:0071634 regulation of transforming growth factor beta production 5/504 41/18722 0.00467090201266356 0.035577119964548 LUM/THBS1/LRRC32/TGFB2/LTBP1 5 GO:1905521 regulation of macrophage migration 5/504 41/18722 0.00467090201266356 0.035577119964548 THBS1/RARRES2/EMILIN1/CD81/MDK 5 GO:0050921 positive regulation of chemotaxis 10/504 141/18722 0.00488512661379595 0.0371426085778471 THBS1/PDGFRB/RARRES2/SEMA5A/GAS6/FGFR1/MDK/TMSB4X/HSPB1/BMPR2 10 GO:0030282 bone mineralization 9/504 119/18722 0.00489564055699424 0.0371564335702245 COL1A2/MGP/DDR2/ENPP1/GPC3/MEF2C/SLC8A1/ISG15/BMPR2 9 GO:0050792 regulation of viral process 11/504 164/18722 0.00493201474550072 0.0373661329920649 AXL/LGALS1/IFITM2/IFITM3/IFITM1/GSN/CAV2/IFI16/ZFP36/ISG15/STOM 11 GO:1904029 regulation of cyclin-dependent protein kinase activity 8/504 98/18722 0.00494742630117801 0.0374165532476702 MYOCD/CAMK2N1/CCND2/NR2F2/ACTB/PKD2/PTEN/CCNG2 8 GO:0035306 positive regulation of dephosphorylation 6/504 59/18722 0.00498037358973414 0.0374667893467148 ITGA1/PDGFRB/DLC1/MEF2C/CALM2/PPP1R12A 6 GO:0046324 regulation of glucose import 6/504 59/18722 0.00498037358973414 0.0374667893467148 ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 6 GO:0090303 positive regulation of wound healing 6/504 59/18722 0.00498037358973414 0.0374667893467148 THBS1/MYLK/ITGB1/FERMT2/XBP1/ACTG1 6 GO:0030500 regulation of bone mineralization 7/504 78/18722 0.00500419968432198 0.037579868631121 MGP/DDR2/ENPP1/MEF2C/SLC8A1/ISG15/BMPR2 7 GO:0006469 negative regulation of protein kinase activity 13/504 212/18722 0.00502929836456921 0.0376360628928271 THY1/MYOCD/CAMK2N1/NR2F2/SLC8A1/PKIG/CAV1/SPRY1/HSPB1/PRKAR1A/AIDA/WWTR1/PTEN 13 GO:0009749 response to glucose 13/504 212/18722 0.00502929836456921 0.0376360628928271 COL6A2/THBS1/CAMK2N1/GAS6/LGALS1/TXNIP/SLC8A1/SOX4/EGR1/MAP4K4/XBP1/PTEN/RAB11FIP2 13 GO:0030308 negative regulation of cell growth 12/504 188/18722 0.00504465396663276 0.0376849762227654 MEG3/CRYAB/WFDC1/SLIT3/SEMA5A/FHL1/ENPP1/TGFB2/RERG/CCDC85B/BMPR2/DCBLD2 12 GO:0048675 axon extension 9/504 120/18722 0.0051701690059632 0.0384133631408177 MAP1B/SLIT3/SEMA5A/VCL/ITGB1/LAMB2/DPYSL2/MACF1/BMPR2 9 GO:0071901 negative regulation of protein serine/threonine kinase activity 9/504 120/18722 0.0051701690059632 0.0384133631408177 MYOCD/NR2F2/SLC8A1/PKIG/CAV1/SPRY1/PRKAR1A/AIDA/PTEN 9 GO:0007520 myoblast fusion 5/504 42/18722 0.00518710754323702 0.0384133631408177 ADAMTS5/EHD2/CD81/MYH9/ADAM12 5 GO:0046596 regulation of viral entry into host cell 5/504 42/18722 0.00518710754323702 0.0384133631408177 LGALS1/IFITM2/IFITM3/IFITM1/GSN 5 GO:1900274 regulation of phospholipase C activity 5/504 42/18722 0.00518710754323702 0.0384133631408177 PDGFRB/EDNRA/PDGFRA/LPAR1/FGFR1 5 GO:0006029 proteoglycan metabolic process 7/504 79/18722 0.00536669608064396 0.0395377454355028 DCN/BGN/SULF2/EXT1/DSEL/UGDH/BMPR2 7 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 7/504 79/18722 0.00536669608064396 0.0395377454355028 DCN/PDGFRB/PDGFRA/HGF/TGFB2/FGFR1/PDGFA 7 GO:0032272 negative regulation of protein polymerization 7/504 79/18722 0.00536669608064396 0.0395377454355028 LMOD1/MYADM/TMSB4X/EPS8/SPTBN1/GSN/SVIL 7 GO:1904019 epithelial cell apoptotic process 9/504 121/18722 0.00545647961535317 0.0401300127304718 THBS1/CD248/SEMA5A/GAS6/MDK/GSN/ZFP36L1/ZFP36/BMPR2 9 GO:0044403 biological process involved in symbiotic interaction 16/504 290/18722 0.00552851197759956 0.0405422647676673 AGTR1/GAS6/AXL/LGALS1/IFITM2/IFI27/IFITM3/IFITM1/CD81/ITGB1/CAV1/GSN/CAV2/JUN/STOM/KPNA3 16 GO:0050900 leukocyte migration 19/504 369/18722 0.00553150956226306 0.0405422647676673 ITGA1/THBS1/THY1/RARRES2/APOD/EMILIN1/GAS6/TGFB2/CD81/ITGB1/MDK/EXT1/EDNRB/IL1R1/MYH9/EPS8/MSN/SOS1/CD99 19 GO:0003171 atrioventricular valve development 4/504 27/18722 0.0055709247548864 0.0405529156348034 SLIT3/TGFB2/SOX4/BMPR2 4 GO:0007263 nitric oxide mediated signal transduction 4/504 27/18722 0.0055709247548864 0.0405529156348034 GUCY1A2/THBS1/ATP2B4/DDAH2 4 GO:0018126 protein hydroxylation 4/504 27/18722 0.0055709247548864 0.0405529156348034 FKBP10/P3H4/CRTAP/PLOD2 4 GO:0031954 positive regulation of protein autophosphorylation 4/504 27/18722 0.0055709247548864 0.0405529156348034 RAP2A/CALM2/PDGFA/NBN 4 GO:0001890 placenta development 10/504 144/18722 0.00565707449083601 0.0405592563979275 DCN/WNT2/NR2F2/IGF2/PKD2/CITED2/ZFP36L1/NOTCH2/HTRA1/BMPR2 10 GO:0014065 phosphatidylinositol 3-kinase signaling 10/504 144/18722 0.00565707449083601 0.0405592563979275 DCN/PDGFRB/PDGFRA/HGF/TGFB2/FGFR1/ZFP36L1/PDGFA/PIK3R1/PTEN 10 GO:0038166 angiotensin-activated signaling pathway 3/504 14/18722 0.00565722368667559 0.0405592563979275 AGTR1/CAV1/ROCK2 3 GO:0044764 multi-organism cellular process 3/504 14/18722 0.00565722368667559 0.0405592563979275 GAS6/CAV1/CAV2 3 GO:0051547 regulation of keratinocyte migration 3/504 14/18722 0.00565722368667559 0.0405592563979275 MAP4K4/ADAM9/PTEN 3 GO:0051764 actin crosslink formation 3/504 14/18722 0.00565722368667559 0.0405592563979275 FLNA/MARCKS/EPS8 3 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 3/504 14/18722 0.00565722368667559 0.0405592563979275 ATP2B4/CAV1/AKAP13 3 GO:0099188 postsynaptic cytoskeleton organization 3/504 14/18722 0.00565722368667559 0.0405592563979275 FARP1/ACTB/ACTG1 3 GO:1905049 negative regulation of metallopeptidase activity 3/504 14/18722 0.00565722368667559 0.0405592563979275 TIMP1/TIMP2/TIMP3 3 GO:0006509 membrane protein ectodomain proteolysis 5/504 43/18722 0.00574240954869874 0.0409162959774238 TIMP1/MYH9/TIMP2/TIMP3/ADAM9 5 GO:0061383 trabecula morphogenesis 5/504 43/18722 0.00574240954869874 0.0409162959774238 COL1A1/TGFB2/MMP2/ADAMTS1/SOS1 5 GO:0071604 transforming growth factor beta production 5/504 43/18722 0.00574240954869874 0.0409162959774238 LUM/THBS1/LRRC32/TGFB2/LTBP1 5 GO:0007422 peripheral nervous system development 7/504 80/18722 0.00574852870429942 0.0409162959774238 LAMA2/PMP22/HAND2/EDNRB/LAMB2/CITED2/GSTM3 7 GO:0051928 positive regulation of calcium ion transport 9/504 122/18722 0.00575490144685974 0.0409162959774238 MYLK/PDGFRB/THY1/HSPA2/CAV1/TSPO/PKD2/CALM2/VMP1 9 GO:0060047 heart contraction 14/504 241/18722 0.00589975428780827 0.0418764951358882 GJC1/FXYD1/TBX2/FLNA/TPM1/TGFB2/SLC8A1/EXT1/ATP2B4/CAV1/GSN/SMAD5/CALM2/MEF2A 14 GO:0032412 regulation of ion transmembrane transporter activity 15/504 267/18722 0.00603905697142422 0.0427941798323312 FXYD1/FHL1/SLMAP/MEF2C/ITGB1/HSPA2/TMSB4X/CAV1/ACTN4/PKD2/CALM2/VMP1/AHNAK/PTEN/STOM 15 GO:0046209 nitric oxide metabolic process 7/504 81/18722 0.00615031559969853 0.0435104280753507 ATP2B4/CAV1/TSPO/DDAH2/PKD2/CYB5R3/ROCK2 7 GO:0045428 regulation of nitric oxide biosynthetic process 6/504 62/18722 0.00635267144732549 0.0448677108998708 ATP2B4/CAV1/TSPO/DDAH2/PKD2/ROCK2 6 GO:0051894 positive regulation of focal adhesion assembly 4/504 28/18722 0.00636344483499016 0.0448696366005164 THY1/LIMS1/FERMT2/MAP4K4 4 GO:0001889 liver development 10/504 147/18722 0.00652114936321596 0.0459058834086027 HGF/LIMS2/SULF2/MDK/PKD2/CITED2/NOTCH2/ARID5B/XBP1/MAN2A1 10 GO:0009746 response to hexose 13/504 219/18722 0.00656508609321142 0.0460410577342876 COL6A2/THBS1/CAMK2N1/GAS6/LGALS1/TXNIP/SLC8A1/SOX4/EGR1/MAP4K4/XBP1/PTEN/RAB11FIP2 13 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 7/504 82/18722 0.00657267615677871 0.0460410577342876 THBS1/HGF/TIMP3/ATF3/PIK3R1/PTEN/PEA15 7 GO:2001057 reactive nitrogen species metabolic process 7/504 82/18722 0.00657267615677871 0.0460410577342876 ATP2B4/CAV1/TSPO/DDAH2/PKD2/CYB5R3/ROCK2 7 GO:2000027 regulation of animal organ morphogenesis 9/504 125/18722 0.00672615977111795 0.0470390846186366 CTHRC1/WNT2/HGF/GPC3/SPRY1/PTK7/CITED2/PDGFA/DAAM1 9 GO:0042110 T cell activation 23/504 487/18722 0.00681190606333324 0.0475609062232401 IGFBP2/THY1/LRRC32/LGALS1/PAG1/TWSG1/CD81/MDK/IL6ST/SOX4/MYH9/CAV1/EGR1/B2M/GSN/IGF2/ZFP36L1/PRKAR1A/MSN/XBP1/STAT3/ZMIZ1/SOS1 23 GO:0001947 heart looping 6/504 63/18722 0.00686576771658511 0.0477808232133032 TBX2/HAND2/MEF2C/PKD2/CITED2/NOTCH2 6 GO:0022617 extracellular matrix disassembly 6/504 63/18722 0.00686576771658511 0.0477808232133032 ADAMTS5/DDR2/CTSK/MMP2/LAMC1/ETS1 6 GO:0045475 locomotor rhythm 3/504 15/18722 0.0069316977937443 0.0478499913936501 EGR1/ZFHX3/PTEN 3 GO:0055012 ventricular cardiac muscle cell differentiation 3/504 15/18722 0.0069316977937443 0.0478499913936501 MYOCD/MEF2C/MEF2A 3 GO:0070831 basement membrane assembly 3/504 15/18722 0.0069316977937443 0.0478499913936501 PXDN/LAMB2/LAMB1 3 GO:0090110 COPII-coated vesicle cargo loading 3/504 15/18722 0.0069316977937443 0.0478499913936501 SEC31A/SEC23A/SEC24D 3 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3/504 15/18722 0.0069316977937443 0.0478499913936501 ZFP36L1/ZFP36/TNRC6B 3 GO:0001763 morphogenesis of a branching structure 12/504 196/18722 0.00697449678822129 0.047925524351569 EDNRA/WNT2/HGF/COL4A1/GPC3/MDK/EXT1/SPRY1/PLXND1/PKD2/PDGFA/PBX1 12 GO:0003197 endocardial cushion development 5/504 45/18722 0.00697628742023776 0.047925524351569 TBX2/TGFB2/JAG1/CITED2/BMPR2 5 GO:0035307 positive regulation of protein dephosphorylation 5/504 45/18722 0.00697628742023776 0.047925524351569 ITGA1/PDGFRB/DLC1/CALM2/PPP1R12A 5 GO:0048678 response to axon injury 7/504 83/18722 0.00701623046990177 0.0480454371761062 MAP1B/APOD/FLNA/LGALS1/LAMB2/TSPO/PTEN 7 GO:0051899 membrane depolarization 7/504 83/18722 0.00701623046990177 0.0480454371761062 DCN/FHL1/SLMAP/SLC8A1/CAV1/TSPO/JUN 7 GO:0002683 negative regulation of immune system process 21/504 434/18722 0.00729974410260361 0.0499068904806803 COL3A1/THBS1/THY1/APOD/EMILIN1/LRRC32/AXL/TGFB2/A2M/PAG1/TWSG1/MDK/SERPING1/FBN1/IFI16/PRKAR1A/HTRA1/ISG15/PIK3R1/AHR/STAT2 21 GO:0046579 positive regulation of Ras protein signal transduction 6/504 64/18722 0.00740822157984005 0.0504869709898828 COL3A1/PDGFRB/LPAR1/NOTCH2/MAP4K4/AKAP13 6 GO:0080164 regulation of nitric oxide metabolic process 6/504 64/18722 0.00740822157984005 0.0504869709898828 ATP2B4/CAV1/TSPO/DDAH2/PKD2/ROCK2 6 GO:0035270 endocrine system development 9/504 127/18722 0.00744035333724926 0.0506252067039269 PDGFRA/MDK/ETS1/SOX4/TSPO/CITED2/ARID5B/CLOCK/PBX1 9 GO:0061008 hepaticobiliary system development 10/504 150/18722 0.00748439799496622 0.0508439310532443 HGF/LIMS2/SULF2/MDK/PKD2/CITED2/NOTCH2/ARID5B/XBP1/MAN2A1 10 GO:0007584 response to nutrient 11/504 174/18722 0.00761074070029167 0.0516201508132481 COL1A1/SPARC/IGFBP2/MAP1B/GAS6/KANK2/LIPG/SLC8A1/TSPO/XBP1/PTEN 11 GO:0061028 establishment of endothelial barrier 5/504 46/18722 0.00765779907672487 0.051857013399121 VCL/MYADM/TJP1/ROCK2/MSN 5 GO:0035303 regulation of dephosphorylation 9/504 128/18722 0.00781847357166401 0.0526807547216279 ITGA1/PDGFRB/DLC1/TGFB2/MEF2C/CALM2/HSP90B1/ROCK2/PPP1R12A 9 GO:0043535 regulation of blood vessel endothelial cell migration 10/504 151/18722 0.0078287571374289 0.0526807547216279 THBS1/FGFR1/MEF2C/TMSB4X/ETS1/ATP2B4/HDAC7/HSPB1/STARD13/AKT3 10 GO:0048754 branching morphogenesis of an epithelial tube 10/504 151/18722 0.0078287571374289 0.0526807547216279 EDNRA/WNT2/COL4A1/GPC3/MDK/EXT1/SPRY1/PLXND1/PKD2/PBX1 10 GO:0071456 cellular response to hypoxia 10/504 151/18722 0.0078287571374289 0.0526807547216279 COX4I2/SLC8A1/MALAT1/EGR1/CITED2/HIPK2/ZFP36L1/EIF4EBP1/ROCK2/PTEN 10 GO:0043270 positive regulation of ion transport 15/504 275/18722 0.00784201595250428 0.0526870034041679 MYLK/PDGFRB/THY1/FXYD1/FHL1/FLNA/ITGB1/HSPA2/TMSB4X/CAV1/ACTN4/TSPO/PKD2/CALM2/VMP1 15 GO:1905475 regulation of protein localization to membrane 11/504 175/18722 0.0079309863482697 0.0532011062263052 GPC3/CD81/ITGB1/ACTB/ATP2B4/SPTBN1/RHOQ/GSN/PIK3R1/STOM/RAB11FIP2 11 GO:0048645 animal organ formation 6/504 65/18722 0.00798094049173448 0.0534522863968361 HAND2/WNT2/MEF2C/EXT1/SPRY1/CITED2 6 GO:0007548 sex differentiation 15/504 276/18722 0.00809473286725155 0.0540085603235918 PDGFRB/SLIT3/PDGFRA/FLNA/AXL/TGFB2/NR2F2/MGST1/FNDC3A/CITED2/SMAD5/ARID5B/ADAMTS1/ATRX/PBX1 15 GO:1903829 positive regulation of cellular protein localization 15/504 276/18722 0.00809473286725155 0.0540085603235918 FLNA/EPB41L2/CD81/ITGB1/ATP2B4/SPTBN1/FERMT2/WWTR1/ROCK2/MSN/PIK3R1/NPTN/STOM/RAB11FIP2/TOMM7 15 GO:0050863 regulation of T cell activation 17/504 329/18722 0.00814008033051178 0.0540085603235918 IGFBP2/THY1/LRRC32/LGALS1/PAG1/TWSG1/CD81/MDK/IL6ST/SOX4/CAV1/B2M/IGF2/PRKAR1A/XBP1/ZMIZ1/SOS1 17 GO:0010001 glial cell differentiation 13/504 225/18722 0.00815925963752029 0.0540085603235918 LAMA2/LAMC3/MXRA8/VIM/METRN/MDK/NFIB/IL6ST/SOX4/SOX6/LAMB2/STAT3/PTEN 13 GO:0036296 response to increased oxygen levels 4/504 30/18722 0.00816511349614797 0.0540085603235918 COL1A1/PDGFRB/FOXO1/CAV1 4 GO:0060351 cartilage development involved in endochondral bone morphogenesis 4/504 30/18722 0.00816511349614797 0.0540085603235918 COL1A1/COL27A1/EXT1/SERPINH1 4 GO:0060674 placenta blood vessel development 4/504 30/18722 0.00816511349614797 0.0540085603235918 WNT2/NR2F2/PKD2/NOTCH2 4 GO:2000637 positive regulation of gene silencing by miRNA 4/504 30/18722 0.00816511349614797 0.0540085603235918 MYOCD/ZFP36/STAT3/TNRC6B 4 GO:0033674 positive regulation of kinase activity 22/504 467/18722 0.00825476911607608 0.054517200050994 THBS1/PDGFRB/DDR2/PDGFRA/GAS6/AXL/TGFB2/CCND2/FGFR1/CD81/ATP2B4/EGR1/IGF2/PKD2/FERMT2/CALM2/PDGFA/ADAM9/BMPR2/TAOK1/NBN/AKAP13 22 GO:0003084 positive regulation of systemic arterial blood pressure 3/504 16/18722 0.00836286150415873 0.0547235944981167 RARRES2/CAMK2N1/NR2F2 3 GO:0009415 response to water 3/504 16/18722 0.00836286150415873 0.0547235944981167 COL18A1/ATP2B4/PKD2 3 GO:0010649 regulation of cell communication by electrical coupling 3/504 16/18722 0.00836286150415873 0.0547235944981167 SLC8A1/CAV1/CALM2 3 GO:0021535 cell migration in hindbrain 3/504 16/18722 0.00836286150415873 0.0547235944981167 FLNA/ITGB1/RBFOX2 3 GO:0070571 negative regulation of neuron projection regeneration 3/504 16/18722 0.00836286150415873 0.0547235944981167 THY1/MAP4K4/PTEN 3 GO:0072109 glomerular mesangium development 3/504 16/18722 0.00836286150415873 0.0547235944981167 ACTA2/PDGFRB/EGR1 3 GO:0045601 regulation of endothelial cell differentiation 5/504 47/18722 0.0083842732369387 0.0547798158125979 ZEB1/JAG1/VCL/ROCK2/VEZF1 5 GO:0042476 odontogenesis 9/504 130/18722 0.00861846914898807 0.0562239979750015 COL1A2/COL1A1/ADAMTS5/HAND2/PDGFRA/TGFB2/FOXO1/LAMB1/HTRA1 9 GO:0046777 protein autophosphorylation 13/504 227/18722 0.00875355637239002 0.0570182109439368 PDGFRB/THY1/DDR2/PDGFRA/ENPP1/PEAK1/RAP2A/FGFR1/CAV1/CALM2/PDGFA/TAOK1/NBN 13 GO:0030856 regulation of epithelial cell differentiation 10/504 154/18722 0.00893542370711922 0.0581142549475196 ZEB1/JAG1/VCL/CAV1/SPRY1/ZFP36L1/ZFP36/WWTR1/ROCK2/VEZF1 10 GO:0032869 cellular response to insulin stimulus 12/504 203/18722 0.00910247974393833 0.0591107841122318 RARRES2/ENPP1/FOXO1/RHOQ/IGF2/CAV2/ZFP36L1/XBP1/PIK3R1/PTEN/PTPRA/EIF4EBP2 12 GO:0060148 positive regulation of posttranscriptional gene silencing 4/504 31/18722 0.00917922656261313 0.0593386310167109 MYOCD/ZFP36/STAT3/TNRC6B 4 GO:0060390 regulation of SMAD protein signal transduction 4/504 31/18722 0.00917922656261313 0.0593386310167109 SPTBN1/RBPMS/WWTR1/BMPR2 4 GO:0090162 establishment of epithelial cell polarity 4/504 31/18722 0.00917922656261313 0.0593386310167109 PTK7/FAT1/MSN/MYO9A 4 GO:0010517 regulation of phospholipase activity 6/504 67/18722 0.0092207665382568 0.0594273535716008 PDGFRB/AGTR1/EDNRA/PDGFRA/LPAR1/FGFR1 6 GO:0061371 determination of heart left/right asymmetry 6/504 67/18722 0.0092207665382568 0.0594273535716008 TBX2/HAND2/MEF2C/PKD2/CITED2/NOTCH2 6 GO:0007569 cell aging 9/504 132/18722 0.00947909286208039 0.0609085169919842 PRELP/TBX2/LIMS1/B2M/CITED2/SMC6/PTEN/ZMIZ1/AKT3 9 GO:0035264 multicellular organism growth 9/504 132/18722 0.00947909286208039 0.0609085169919842 EXT1/IGF2/ZFP36L1/NOTCH2/ARID5B/WWTR1/ATRX/STAT3/SOS1 9 GO:1903522 regulation of blood circulation 14/504 256/18722 0.00979691930194287 0.0628562104762791 GJC1/AGTR1/FXYD1/TBX2/FLNA/TPM1/TGFB2/ARHGAP42/SLC8A1/ATP2B4/CAV1/CALM2/MEF2A/BMPR2 14 GO:0002237 response to molecule of bacterial origin 18/504 363/18722 0.00985034307831717 0.0631042218495491 DCN/SPARC/SPON2/AKAP12/AXL/TFPI/VIM/MTDH/MGST1/MEF2C/EDNRB/B2M/TSPO/ZFP36/JUN/ADAM9/XBP1/NR4A1 18 GO:0032922 circadian regulation of gene expression 6/504 68/18722 0.00988964818598487 0.0631623715836779 ID4/EGR1/ZFHX3/CLOCK/KMT2A/AHR 6 GO:1903037 regulation of leukocyte cell-cell adhesion 17/504 336/18722 0.00990957859414081 0.0631623715836779 IGFBP2/THY1/LRRC32/LGALS1/PAG1/TWSG1/CD81/MDK/ETS1/IL6ST/SOX4/CAV1/B2M/IGF2/PRKAR1A/XBP1/ZMIZ1 17 GO:0003184 pulmonary valve morphogenesis 3/504 17/18722 0.00995467072339134 0.0631623715836779 TGFB2/JAG1/NOTCH2 3 GO:0055003 cardiac myofibril assembly 3/504 17/18722 0.00995467072339134 0.0631623715836779 PDGFRB/PDGFRA/MEF2A 3 GO:0008038 neuron recognition 5/504 49/18722 0.00997767395716886 0.0631623715836779 SEMA5A/NEXN/PALLD/EXT1/NPTN 5 GO:0034332 adherens junction organization 5/504 49/18722 0.00997767395716886 0.0631623715836779 CDH11/VCL/ACTB/TJP1/FERMT2 5 GO:0038084 vascular endothelial growth factor signaling pathway 5/504 49/18722 0.00997767395716886 0.0631623715836779 DCN/PDGFRB/ADGRA2/PDGFRA/HSPB1 5 GO:0045778 positive regulation of ossification 5/504 49/18722 0.00997767395716886 0.0631623715836779 TGFB2/MEF2C/SLC8A1/ISG15/BMPR2 5 GO:0010644 cell communication by electrical coupling 4/504 32/18722 0.0102719596093699 0.0644118407972989 GJC1/SLC8A1/CAV1/CALM2 4 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 4/504 32/18722 0.0102719596093699 0.0644118407972989 HSPB6/HAND2/MYOCD/MDK 4 GO:0019934 cGMP-mediated signaling 4/504 32/18722 0.0102719596093699 0.0644118407972989 THBS1/PRKG1/PDE3A/EDNRB 4 GO:0035456 response to interferon-beta 4/504 32/18722 0.0102719596093699 0.0644118407972989 IFITM2/IFITM3/IFITM1/IFI16 4 GO:0060317 cardiac epithelial to mesenchymal transition 4/504 32/18722 0.0102719596093699 0.0644118407972989 WNT2/TGFB2/JAG1/SPRY1 4 GO:0061036 positive regulation of cartilage development 4/504 32/18722 0.0102719596093699 0.0644118407972989 MDK/SOX6/BMP1/BMPR2 4 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 8/504 111/18722 0.0102805699564142 0.0644118407972989 DCN/PDGFRB/PDGFRA/HGF/TGFB2/FGFR1/PDGFA/PTEN 8 GO:0003143 embryonic heart tube morphogenesis 6/504 69/18722 0.0105923415385644 0.0660745626193954 TBX2/HAND2/MEF2C/PKD2/CITED2/NOTCH2 6 GO:0060193 positive regulation of lipase activity 6/504 69/18722 0.0105923415385644 0.0660745626193954 PDGFRB/AGTR1/EDNRA/PDGFRA/LPAR1/FGFR1 6 GO:1904377 positive regulation of protein localization to cell periphery 6/504 69/18722 0.0105923415385644 0.0660745626193954 EPB41L2/ITGB1/ATP2B4/SPTBN1/PIK3R1/RAB11FIP2 6 GO:0035304 regulation of protein dephosphorylation 7/504 90/18722 0.0107664761376907 0.0670629045719424 ITGA1/PDGFRB/DLC1/CALM2/HSP90B1/ROCK2/PPP1R12A 7 GO:0010633 negative regulation of epithelial cell migration 8/504 112/18722 0.0108193221174609 0.0672939787596951 DCN/THBS1/ADAMTS9/NR2F2/MEF2C/ATP2B4/STARD13/PTEN 8 GO:0010665 regulation of cardiac muscle cell apoptotic process 5/504 50/18722 0.0108473007189421 0.0673699360058715 HSPB6/HAND2/MYOCD/MDK/PTEN 5 GO:0048588 developmental cell growth 13/504 234/18722 0.0111054040793791 0.0687730313495461 MAP1B/SLIT3/SEMA5A/SORBS2/PDLIM5/VCL/ITGB1/EXT1/LAMB2/DPYSL2/MACF1/BMPR2/AKAP13 13 GO:0060560 developmental growth involved in morphogenesis 13/504 234/18722 0.0111054040793791 0.0687730313495461 MAP1B/SLIT3/SEMA5A/TBX2/VCL/ITGB1/EXT1/SPRY1/PTK7/LAMB2/DPYSL2/MACF1/BMPR2 13 GO:0072080 nephron tubule development 7/504 91/18722 0.0114017776712586 0.0702679918985298 JAG1/GPC3/MEF2C/PKD2/NOTCH2/WWTR1/PBX1 7 GO:0003382 epithelial cell morphogenesis 4/504 33/18722 0.0114454767988244 0.0702679918985298 COL18A1/COL15A1/PALLD/FAT1 4 GO:0034110 regulation of homotypic cell-cell adhesion 4/504 33/18722 0.0114454767988244 0.0702679918985298 PRKG1/LGALS1/IL6ST/JAK1 4 GO:0035025 positive regulation of Rho protein signal transduction 4/504 33/18722 0.0114454767988244 0.0702679918985298 COL3A1/PDGFRB/LPAR1/AKAP13 4 GO:0048048 embryonic eye morphogenesis 4/504 33/18722 0.0114454767988244 0.0702679918985298 TBX2/FBN1/CITED2/HIPK2 4 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 4/504 33/18722 0.0114454767988244 0.0702679918985298 MYOCD/CAMK2N1/NR2F2/PTEN 4 GO:0043116 negative regulation of vascular permeability 3/504 18/18722 0.0117104009754005 0.0713816595832903 AKAP12/PDE3A/FERMT2 3 GO:0060008 Sertoli cell differentiation 3/504 18/18722 0.0117104009754005 0.0713816595832903 FLNA/FNDC3A/ATRX 3 GO:0061484 hematopoietic stem cell homeostasis 3/504 18/18722 0.0117104009754005 0.0713816595832903 EXT1/FSTL1/SOX4 3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3/504 18/18722 0.0117104009754005 0.0713816595832903 ZFP36L1/ZFP36/TNRC6B 3 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus 3/504 18/18722 0.0117104009754005 0.0713816595832903 DCN/ADGRA2/ATP2B4 3 GO:0045668 negative regulation of osteoblast differentiation 5/504 51/18722 0.0117672859526858 0.0716262291678438 IGFBP5/HAND2/TWSG1/HDAC7/CRIM1 5 GO:1903131 mononuclear cell differentiation 20/504 426/18722 0.0118528287983109 0.0720442922548825 GAS6/AXL/LGALS1/ITGB1/MDK/KLF6/SOX4/MYH9/EGR1/B2M/ZFP36L1/NOTCH2/IFI16/JUN/XBP1/STAT3/PIK3R1/ZMIZ1/PBX1/SOS1 20 GO:0055123 digestive system development 9/504 137/18722 0.0119139669197817 0.0722104690045774 RARRES2/TBX2/MYOCD/PDGFRA/TGFB2/EXT1/EDNRB/IL6ST/IGF2 9 GO:0090090 negative regulation of canonical Wnt signaling pathway 9/504 137/18722 0.0119139669197817 0.0722104690045774 IGFBP2/IGFBP4/CTHRC1/GPC3/MDK/CAV1/EGR1/RBMS3/WWTR1 9 GO:0021987 cerebral cortex development 8/504 114/18722 0.0119590724989075 0.0723138105679293 COL3A1/FLNA/MDK/BTBD3/SLC38A2/LAMB1/TACC1/ZMIZ1 8 GO:0032496 response to lipopolysaccharide 17/504 343/18722 0.0119727569008992 0.0723138105679293 DCN/SPARC/SPON2/AKAP12/AXL/TFPI/VIM/MTDH/MGST1/MEF2C/EDNRB/TSPO/ZFP36/JUN/ADAM9/XBP1/NR4A1 17 GO:0036294 cellular response to decreased oxygen levels 10/504 161/18722 0.0119817874753321 0.0723138105679293 COX4I2/SLC8A1/MALAT1/EGR1/CITED2/HIPK2/ZFP36L1/EIF4EBP1/ROCK2/PTEN 10 GO:0048525 negative regulation of viral process 7/504 92/18722 0.0120637804552868 0.0727059716296762 IFITM2/IFITM3/IFITM1/GSN/IFI16/ZFP36/ISG15 7 GO:0003208 cardiac ventricle morphogenesis 6/504 71/18722 0.0121025902202966 0.0727346948119934 HAND2/TPM1/TGFB2/JAG1/MEF2C/SOX4 6 GO:0003281 ventricular septum development 6/504 71/18722 0.0121025902202966 0.0727346948119934 SLIT3/TGFB2/SOX4/PTK7/CITED2/BMPR2 6 GO:0071478 cellular response to radiation 11/504 186/18722 0.0121872647318168 0.0731407053357486 CRYAB/TIMP1/CCND2/MMP2/CRIP1/EGR1/IFI16/RHOB/CLOCK/POLK/PIK3R1 11 GO:0033673 negative regulation of kinase activity 13/504 237/18722 0.0122521450891731 0.0734269508640064 THY1/MYOCD/CAMK2N1/NR2F2/SLC8A1/PKIG/CAV1/SPRY1/HSPB1/PRKAR1A/AIDA/WWTR1/PTEN 13 GO:0044319 wound healing, spreading of cells 4/504 34/18722 0.0127018101807542 0.075706908894568 COL5A1/FLNA/FERMT2/PTEN 4 GO:0050931 pigment cell differentiation 4/504 34/18722 0.0127018101807542 0.075706908894568 ENPP1/ZEB2/MEF2C/EDNRB 4 GO:0090505 epiboly involved in wound healing 4/504 34/18722 0.0127018101807542 0.075706908894568 COL5A1/FLNA/FERMT2/PTEN 4 GO:0010662 regulation of striated muscle cell apoptotic process 5/504 52/18722 0.0127388877826338 0.075706908894568 HSPB6/HAND2/MYOCD/MDK/PTEN 5 GO:0030514 negative regulation of BMP signaling pathway 5/504 52/18722 0.0127388877826338 0.075706908894568 TWSG1/FBN1/HIPK2/HTRA1/CRIM1 5 GO:0051496 positive regulation of stress fiber assembly 5/504 52/18722 0.0127388877826338 0.075706908894568 TPM1/LPAR1/SORBS3/FERMT2/ROCK2 5 GO:0055021 regulation of cardiac muscle tissue growth 6/504 72/18722 0.0129118255432579 0.0765218176786974 TBX2/WNT2/MEIS1/MEF2C/CITED2/PTEN 6 GO:0071479 cellular response to ionizing radiation 6/504 72/18722 0.0129118255432579 0.0765218176786974 CRYAB/CCND2/EGR1/IFI16/RHOB/CLOCK 6 GO:1903039 positive regulation of leukocyte cell-cell adhesion 13/504 239/18722 0.013066066595952 0.0773286739120541 IGFBP2/THY1/LGALS1/CD81/MDK/ETS1/IL6ST/SOX4/CAV1/B2M/IGF2/XBP1/ZMIZ1 13 GO:0030518 intracellular steroid hormone receptor signaling pathway 8/504 116/18722 0.0131847692458605 0.077815633960721 PLPP1/KANK2/NR3C1/NCOR2/DDX17/CLOCK/RBFOX2/ZMIZ1 8 GO:0043200 response to amino acid 8/504 116/18722 0.0131847692458605 0.077815633960721 COL1A2/COL1A1/COL6A1/PDGFRA/COL5A2/COL4A1/MMP2/XBP1 8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 7/504 94/18722 0.01347025302594 0.0792550834434094 MYOCD/CCND2/NR2F2/ACTB/PKD2/PTEN/CCNG2 7 GO:0003085 negative regulation of systemic arterial blood pressure 3/504 19/18722 0.0136326904589061 0.0792550834434094 ARHGAP42/KCNK6/BMPR2 3 GO:0010002 cardioblast differentiation 3/504 19/18722 0.0136326904589061 0.0792550834434094 TBX2/MYOCD/TGFB2 3 GO:0010544 negative regulation of platelet activation 3/504 19/18722 0.0136326904589061 0.0792550834434094 PRKG1/PDGFRA/PDGFA 3 GO:0010759 positive regulation of macrophage chemotaxis 3/504 19/18722 0.0136326904589061 0.0792550834434094 THBS1/RARRES2/MDK 3 GO:0030220 platelet formation 3/504 19/18722 0.0136326904589061 0.0792550834434094 MEF2C/MYH9/ACTN1 3 GO:0035313 wound healing, spreading of epidermal cells 3/504 19/18722 0.0136326904589061 0.0792550834434094 COL5A1/FERMT2/PTEN 3 GO:0036344 platelet morphogenesis 3/504 19/18722 0.0136326904589061 0.0792550834434094 MEF2C/MYH9/ACTN1 3 GO:0046794 transport of virus 3/504 19/18722 0.0136326904589061 0.0792550834434094 CAV1/CAV2/KPNA3 3 GO:0051546 keratinocyte migration 3/504 19/18722 0.0136326904589061 0.0792550834434094 MAP4K4/ADAM9/PTEN 3 GO:1901881 positive regulation of protein depolymerization 3/504 19/18722 0.0136326904589061 0.0792550834434094 SEMA5A/DSTN/CFL2 3 GO:0061035 regulation of cartilage development 6/504 73/18722 0.0137582304489698 0.0797973997590944 CTSK/MAF/MDK/SOX6/BMP1/BMPR2 6 GO:0071320 cellular response to cAMP 5/504 53/18722 0.0137633240398906 0.0797973997590944 IGFBP5/SLC8A1/PKD2/ZFP36L1/AHR 5 GO:0046661 male sex differentiation 10/504 165/18722 0.0140423602222465 0.0806520590745106 PDGFRB/PDGFRA/FLNA/TGFB2/MGST1/FNDC3A/CITED2/SMAD5/ARID5B/ATRX 10 GO:0001569 branching involved in blood vessel morphogenesis 4/504 35/18722 0.0140428579338722 0.0806520590745106 EDNRA/COL4A1/MDK/PLXND1 4 GO:0010664 negative regulation of striated muscle cell apoptotic process 4/504 35/18722 0.0140428579338722 0.0806520590745106 HSPB6/HAND2/MYOCD/MDK 4 GO:0010837 regulation of keratinocyte proliferation 4/504 35/18722 0.0140428579338722 0.0806520590745106 MDK/ZFP36L1/NOTCH2/ZFP36 4 GO:0018149 peptide cross-linking 4/504 35/18722 0.0140428579338722 0.0806520590745106 COL3A1/DCN/THBS1/BGN 4 GO:0090504 epiboly 4/504 35/18722 0.0140428579338722 0.0806520590745106 COL5A1/FLNA/FERMT2/PTEN 4 GO:1905207 regulation of cardiocyte differentiation 4/504 35/18722 0.0140428579338722 0.0806520590745106 MYOCD/TGFB2/MEF2C/SOX6 4 GO:0008584 male gonad development 9/504 141/18722 0.0141759360058029 0.0812155194945395 PDGFRB/PDGFRA/FLNA/TGFB2/MGST1/FNDC3A/CITED2/ARID5B/ATRX 9 GO:0051348 negative regulation of transferase activity 14/504 268/18722 0.0141789790645744 0.0812155194945395 THY1/MYOCD/CAMK2N1/NR2F2/SLC8A1/PKIG/CAV1/SPRY1/HSPB1/PRKAR1A/ZFP36/AIDA/WWTR1/PTEN 14 GO:0008593 regulation of Notch signaling pathway 7/504 95/18722 0.0142158885182964 0.0813179272271493 DLK1/TGFB2/JAG1/IL6ST/EPN2/STAT3/ZMIZ1 7 GO:0050870 positive regulation of T cell activation 12/504 216/18722 0.0143617473974313 0.0820424420176789 IGFBP2/THY1/LGALS1/CD81/MDK/IL6ST/SOX4/CAV1/B2M/IGF2/XBP1/ZMIZ1 12 GO:0046323 glucose import 6/504 74/18722 0.0146426068130873 0.0835351921392818 ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 6 GO:0007009 plasma membrane organization 9/504 142/18722 0.0147878887151857 0.0841393455126345 COL5A1/EHD2/TGFB2/MYH9/CAV1/SPTBN1/GSN/CAV2/PTEN 9 GO:0046546 development of primary male sexual characteristics 9/504 142/18722 0.0147878887151857 0.0841393455126345 PDGFRB/PDGFRA/FLNA/TGFB2/MGST1/FNDC3A/CITED2/ARID5B/ATRX 9 GO:0016358 dendrite development 13/504 243/18722 0.0148182649712359 0.0842000614655464 MAP1B/SDC2/PRKG1/FARP1/RAP2A/PDLIM5/MEF2C/ITGB1/BTBD3/ITSN1/MEF2A/RBFOX2/PTEN 13 GO:0010659 cardiac muscle cell apoptotic process 5/504 54/18722 0.0148417705315656 0.0842216274653116 HSPB6/HAND2/MYOCD/MDK/PTEN 5 GO:0010769 regulation of cell morphogenesis involved in differentiation 7/504 96/18722 0.0149905555265357 0.0849531084414945 FLNA/LIMS2/MDK/MYADM/LIMS1/ACTN4/FERMT2 7 GO:0032872 regulation of stress-activated MAPK cascade 11/504 192/18722 0.0151437881383631 0.0857078234638747 HAND2/HGF/TGFB2/FOXO1/RAP2A/HIPK2/MAP4K4/ZMYND11/AIDA/PJA2/TAOK1 11 GO:0034767 positive regulation of ion transmembrane transport 10/504 167/18722 0.0151669552858698 0.0857253967414306 THY1/FXYD1/FLNA/ITGB1/HSPA2/TMSB4X/ACTN4/PKD2/CALM2/VMP1 10 GO:0002691 regulation of cellular extravasation 4/504 36/18722 0.015470383155297 0.0870947921246168 THY1/MDK/IL1R1/CD99 4 GO:0010092 specification of animal organ identity 4/504 36/18722 0.015470383155297 0.0870947921246168 WNT2/MEF2C/EXT1/SPRY1 4 GO:0030224 monocyte differentiation 4/504 36/18722 0.015470383155297 0.0870947921246168 MYH9/ZFP36L1/IFI16/JUN 4 GO:0007565 female pregnancy 11/504 193/18722 0.0156848050695028 0.0881717346112907 IGFBP7/IGFBP5/IGFBP2/TIMP1/MMP2/NR2F2/ETS1/SLC38A2/CITED2/VMP1/BMPR2 11 GO:0060044 negative regulation of cardiac muscle cell proliferation 3/504 20/18722 0.0157235810376325 0.0881717346112907 MEIS1/CITED2/PTEN 3 GO:2000479 regulation of cAMP-dependent protein kinase activity 3/504 20/18722 0.0157235810376325 0.0881717346112907 PKIG/ATP2B4/PRKAR1A 3 GO:0010596 negative regulation of endothelial cell migration 7/504 97/18722 0.0157948184245561 0.0883393444085446 DCN/THBS1/ADAMTS9/NR2F2/MEF2C/ATP2B4/STARD13 7 GO:0070252 actin-mediated cell contraction 7/504 97/18722 0.0157948184245561 0.0883393444085446 GJC1/FLNA/TPM1/MYL6/CAV1/GSN/PARVA 7 GO:0097191 extrinsic apoptotic signaling pathway 12/504 219/18722 0.0158509454769568 0.0885373725791324 THBS1/HGF/TGFB2/IFI27/FGFR1/CAV1/TIMP3/ZMYND11/ATF3/PIK3R1/PTEN/PEA15 12 GO:0038066 p38MAPK cascade 5/504 55/18722 0.0159753594458478 0.0891158105902187 HAND2/HGF/ZFP36L1/ZFP36/PJA2 5 GO:0031668 cellular response to extracellular stimulus 13/504 246/18722 0.0162462471502594 0.09050875368065 COL1A1/MYOCD/GAS6/AXL/KANK2/FOXO1/SLC38A2/IFI16/MAP1LC3A/JUN/XBP1/ATF3/BMPR2 13 GO:0021543 pallium development 10/504 169/18722 0.016357307290491 0.0910088203805573 COL3A1/FLNA/MDK/ATP2B4/BTBD3/SLC38A2/LAMB1/TACC1/PTEN/ZMIZ1 10 GO:0001937 negative regulation of endothelial cell proliferation 6/504 76/18722 0.0165283953940202 0.0918411359150176 SPARC/THBS1/NR2F2/MEF2C/CAV1/CAV2 6 GO:0061337 cardiac conduction 7/504 98/18722 0.0166292332032775 0.0922814460748112 GJC1/FLNA/SLC8A1/ATP2B4/CAV1/CALM2/MEF2A 7 GO:0070302 regulation of stress-activated protein kinase signaling cascade 11/504 195/18722 0.0168102069555123 0.0931647397158289 HAND2/HGF/TGFB2/FOXO1/RAP2A/HIPK2/MAP4K4/ZMYND11/AIDA/PJA2/TAOK1 11 GO:0008406 gonad development 12/504 221/18722 0.0169067501195758 0.0935784239131442 PDGFRB/SLIT3/PDGFRA/FLNA/TGFB2/NR2F2/MGST1/FNDC3A/CITED2/ARID5B/ADAMTS1/ATRX 12 GO:0030178 negative regulation of Wnt signaling pathway 10/504 170/18722 0.016977811994841 0.0936532054394008 IGFBP2/IGFBP4/CTHRC1/NXN/GPC3/MDK/CAV1/EGR1/RBMS3/WWTR1 10 GO:0030513 positive regulation of BMP signaling pathway 4/504 37/18722 0.0169860131559877 0.0936532054394008 TWSG1/GPC3/NOTCH2/BMPR2 4 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 4/504 37/18722 0.0169860131559877 0.0936532054394008 THBS1/SULF2/SPRY1/NPTN 4 GO:0045786 negative regulation of cell cycle 18/504 385/18722 0.0170561212678501 0.093918564661757 MYOCD/FHL1/CAMK2N1/KANK2/GAS1/NR2F2/SOX4/TIMP2/PKD2/ZFP36L1/RHOB/PRKAR1A/CLOCK/ATRX/NR4A1/PTEN/TAOK1/NBN 18 GO:0010658 striated muscle cell apoptotic process 5/504 56/18722 0.0171651778910093 0.0941550771864993 HSPB6/HAND2/MYOCD/MDK/PTEN 5 GO:0045071 negative regulation of viral genome replication 5/504 56/18722 0.0171651778910093 0.0941550771864993 IFITM2/IFITM3/IFITM1/IFI16/ISG15 5 GO:0071385 cellular response to glucocorticoid stimulus 5/504 56/18722 0.0171651778910093 0.0941550771864993 FOXO1/NR3C1/ZFP36L1/ZFP36/FBXO32 5 GO:0021537 telencephalon development 13/504 248/18722 0.0172548309169844 0.0945255032157361 COL3A1/FLNA/SLC8A1/MDK/NFIB/EXT1/ATP2B4/BTBD3/SLC38A2/LAMB1/TACC1/PTEN/ZMIZ1 13 GO:0048813 dendrite morphogenesis 9/504 146/18722 0.0174315992911741 0.0953716053408285 SDC2/FARP1/RAP2A/PDLIM5/ITGB1/BTBD3/MEF2A/RBFOX2/PTEN 9 GO:0045860 positive regulation of protein kinase activity 18/504 386/18722 0.0174613025873912 0.0954119513502845 THBS1/PDGFRB/DDR2/GAS6/TGFB2/CCND2/FGFR1/ATP2B4/EGR1/IGF2/PKD2/FERMT2/CALM2/PDGFA/ADAM9/BMPR2/TAOK1/AKAP13 18 GO:0048644 muscle organ morphogenesis 6/504 77/18722 0.0175313226000346 0.095672211328158 MYLK/EFEMP2/WNT2/TPM1/TGFB2/ARID5B 6 GO:0030833 regulation of actin filament polymerization 10/504 171/18722 0.0176155569573622 0.096009279182154 LMOD1/ELN/MYADM/TMSB4X/EPS8/SPTBN1/GSN/CDC42EP3/NCKAP1/SVIL 10 GO:0001502 cartilage condensation 3/504 21/18722 0.0179845572507171 0.096583168234818 MGP/SOX6/BMP1 3 GO:0030449 regulation of complement activation 3/504 21/18722 0.0179845572507171 0.096583168234818 CFH/A2M/SERPING1 3 GO:0044342 type B pancreatic cell proliferation 3/504 21/18722 0.0179845572507171 0.096583168234818 IGFBP5/IGFBP4/NR4A1 3 GO:0044766 multi-organism transport 3/504 21/18722 0.0179845572507171 0.096583168234818 CAV1/CAV2/KPNA3 3 GO:0048745 smooth muscle tissue development 3/504 21/18722 0.0179845572507171 0.096583168234818 MYLK/EFEMP2/PKD2 3 GO:0060445 branching involved in salivary gland morphogenesis 3/504 21/18722 0.0179845572507171 0.096583168234818 HGF/PLXND1/PDGFA 3 GO:0072111 cell proliferation involved in kidney development 3/504 21/18722 0.0179845572507171 0.096583168234818 PDGFRB/GPC3/EGR1 3 GO:0072243 metanephric nephron epithelium development 3/504 21/18722 0.0179845572507171 0.096583168234818 LAMB2/PKD2/WWTR1 3 GO:1902579 multi-organism localization 3/504 21/18722 0.0179845572507171 0.096583168234818 CAV1/CAV2/KPNA3 3 GO:1905209 positive regulation of cardiocyte differentiation 3/504 21/18722 0.0179845572507171 0.096583168234818 MYOCD/TGFB2/MEF2C 3 GO:2001014 regulation of skeletal muscle cell differentiation 3/504 21/18722 0.0179845572507171 0.096583168234818 MYOCD/MEF2C/DDX17 3 GO:0042594 response to starvation 11/504 197/18722 0.0179949015656265 0.096583168234818 GAS6/FOXO1/SLC38A2/IFI16/EIF4EBP1/ZFP36/MAP1LC3A/JUN/XBP1/ATF3/BMPR2 11 GO:0050920 regulation of chemotaxis 12/504 223/18722 0.0180146934432834 0.096583168234818 THBS1/PDGFRB/RARRES2/SEMA5A/ADGRA2/PDGFRA/GAS6/FGFR1/MDK/TMSB4X/HSPB1/BMPR2 12 GO:0031667 response to nutrient levels 21/504 474/18722 0.0182022422236813 0.0974663922578824 COL1A1/SPARC/IGFBP2/MAP1B/RARRES2/GAS6/KANK2/FOXO1/LIPG/SLC8A1/SLC38A2/TSPO/IFI16/EIF4EBP1/ZFP36/MAP1LC3A/JUN/XBP1/ATF3/PTEN/BMPR2 21 GO:0033619 membrane protein proteolysis 5/504 57/18722 0.0184122665660397 0.0984676032999843 TIMP1/MYH9/TIMP2/TIMP3/ADAM9 5 GO:0035050 embryonic heart tube development 6/504 78/18722 0.0185752495096773 0.0988064243754706 TBX2/HAND2/MEF2C/PKD2/CITED2/NOTCH2 6 GO:0070373 negative regulation of ERK1 and ERK2 cascade 6/504 78/18722 0.0185752495096773 0.0988064243754706 EMILIN1/CAMK2N1/SPRY1/TIMP3/ATF3/PTEN 6 GO:0010613 positive regulation of cardiac muscle hypertrophy 4/504 38/18722 0.0185912392225318 0.0988064243754706 HAND2/IL6ST/ROCK2/MEF2A 4 GO:0035886 vascular associated smooth muscle cell differentiation 4/504 38/18722 0.0185912392225318 0.0988064243754706 MYOCD/EFEMP2/SGCB/EPC1 4 GO:0048246 macrophage chemotaxis 4/504 38/18722 0.0185912392225318 0.0988064243754706 THBS1/RARRES2/MDK/EDNRB 4 GO:1903900 regulation of viral life cycle 9/504 148/18722 0.0188756007755092 0.100193095793479 AXL/LGALS1/IFITM2/IFITM3/IFITM1/GSN/CAV2/IFI16/ISG15 9 GO:0051099 positive regulation of binding 10/504 173/18722 0.0189438212264475 0.100430456700509 CTHRC1/HAND2/MYOCD/RAMP1/CAV1/B2M/PLXND1/HIPK2/CALM2/CTBP2 10 GO:0050769 positive regulation of neurogenesis 12/504 225/18722 0.0191762518085113 0.10153670877047 MAP1B/SEMA5A/WNT2/METRN/MDK/IL6ST/PLXND1/TSPO/MACF1/NPTN/MAN2A1/BMPR2 12 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 6/504 79/18722 0.019660884038091 0.103717231475016 FLNA/LIMS2/MDK/MYADM/LIMS1/FERMT2 6 GO:0050772 positive regulation of axonogenesis 6/504 79/18722 0.019660884038091 0.103717231475016 MAP1B/SEMA5A/METRN/PLXND1/MACF1/BMPR2 6 GO:0060420 regulation of heart growth 6/504 79/18722 0.019660884038091 0.103717231475016 TBX2/WNT2/MEIS1/MEF2C/CITED2/PTEN 6 GO:0086065 cell communication involved in cardiac conduction 5/504 58/18722 0.0197176185603628 0.103760325256687 GJC1/FLNA/SLC8A1/CAV1/CALM2 5 GO:2000736 regulation of stem cell differentiation 5/504 58/18722 0.0197176185603628 0.103760325256687 PDGFRA/TGFB2/JAG1/SOX6/STAT3 5 GO:1904375 regulation of protein localization to cell periphery 8/504 125/18722 0.0198566340298944 0.104363342201401 EPB41L2/ITGB1/ACTB/ATP2B4/SPTBN1/RHOQ/PIK3R1/RAB11FIP2 8 GO:0014742 positive regulation of muscle hypertrophy 4/504 39/18722 0.0202874168078965 0.105745528460711 HAND2/IL6ST/ROCK2/MEF2A 4 GO:0046326 positive regulation of glucose import 4/504 39/18722 0.0202874168078965 0.105745528460711 GPC3/RHOQ/MEF2A/PIK3R1 4 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 4/504 39/18722 0.0202874168078965 0.105745528460711 HSPA2/PKD2/CALM2/VMP1 4 GO:1902742 apoptotic process involved in development 4/504 39/18722 0.0202874168078965 0.105745528460711 CRYAB/SLIT3/HAND2/TGFB2 4 GO:2000249 regulation of actin cytoskeleton reorganization 4/504 39/18722 0.0202874168078965 0.105745528460711 PDGFRA/MDK/TJP1/NOTCH2 4 GO:0045137 development of primary sexual characteristics 12/504 227/18722 0.0203928900980466 0.105745528460711 PDGFRB/SLIT3/PDGFRA/FLNA/TGFB2/NR2F2/MGST1/FNDC3A/CITED2/ARID5B/ADAMTS1/ATRX 12 GO:0002089 lens morphogenesis in camera-type eye 3/504 22/18722 0.0204165834261845 0.105745528460711 MEIS1/CITED2/HIPK2 3 GO:0035024 negative regulation of Rho protein signal transduction 3/504 22/18722 0.0204165834261845 0.105745528460711 DLC1/ARHGAP42/ITGB1 3 GO:0051220 cytoplasmic sequestering of protein 3/504 22/18722 0.0204165834261845 0.105745528460711 FLNA/TMSB4X/PKD2 3 GO:0060343 trabecula formation 3/504 22/18722 0.0204165834261845 0.105745528460711 COL1A1/MMP2/ADAMTS1 3 GO:0060965 negative regulation of gene silencing by miRNA 3/504 22/18722 0.0204165834261845 0.105745528460711 KCNQ1OT1/NCOR2/STAT3 3 GO:2000725 regulation of cardiac muscle cell differentiation 3/504 22/18722 0.0204165834261845 0.105745528460711 MYOCD/MEF2C/SOX6 3 GO:0007611 learning or memory 13/504 255/18722 0.0211613643230233 0.109413195707311 GATM/ADCY3/CCND2/ATXN1/MEF2C/ITGB1/MDK/B2M/JUN/NPTN/PJA2/PTEN/EIF4EBP2 13 GO:1904064 positive regulation of cation transmembrane transport 9/504 151/18722 0.0212015272749014 0.109413195707311 THY1/FXYD1/FLNA/HSPA2/TMSB4X/ACTN4/PKD2/CALM2/VMP1 9 GO:2001236 regulation of extrinsic apoptotic signaling pathway 9/504 151/18722 0.0212015272749014 0.109413195707311 THBS1/HGF/FGFR1/CAV1/TIMP3/ZMYND11/ATF3/PTEN/PEA15 9 GO:0045639 positive regulation of myeloid cell differentiation 7/504 103/18722 0.0212723923471075 0.109646480698661 JAG1/ETS1/ZFP36L1/NOTCH2/ISG15/JUN/STAT3 7 GO:0048565 digestive tract development 8/504 127/18722 0.0216160504318912 0.111283594572857 RARRES2/TBX2/MYOCD/PDGFRA/TGFB2/EXT1/EDNRB/IL6ST 8 GO:0001960 negative regulation of cytokine-mediated signaling pathway 6/504 81/18722 0.0219600006288782 0.112431166404198 PXDN/SLIT3/GAS6/CAV1/ISG15/STAT2 6 GO:0014032 neural crest cell development 6/504 81/18722 0.0219600006288782 0.112431166404198 SEMA5A/EDNRA/HAND2/JAG1/EDNRB/CITED2 6 GO:0060968 regulation of gene silencing 6/504 81/18722 0.0219600006288782 0.112431166404198 MYOCD/KCNQ1OT1/NCOR2/ZFP36/STAT3/TNRC6B 6 GO:0010543 regulation of platelet activation 4/504 40/18722 0.0220757661158722 0.112431166404198 PRKG1/PDGFRA/IL6ST/PDGFA 4 GO:0030501 positive regulation of bone mineralization 4/504 40/18722 0.0220757661158722 0.112431166404198 MEF2C/SLC8A1/ISG15/BMPR2 4 GO:0035329 hippo signaling 4/504 40/18722 0.0220757661158722 0.112431166404198 TEAD1/WWTR1/AMOTL2/PJA2 4 GO:0045777 positive regulation of blood pressure 4/504 40/18722 0.0220757661158722 0.112431166404198 RARRES2/CAMK2N1/TPM1/NR2F2 4 GO:0055081 anion homeostasis 4/504 40/18722 0.0220757661158722 0.112431166404198 ENPP1/CYBRD1/CKB/GLS 4 GO:0071526 semaphorin-plexin signaling pathway 4/504 40/18722 0.0220757661158722 0.112431166404198 SEMA5A/HAND2/FLNA/PLXND1 4 GO:1903076 regulation of protein localization to plasma membrane 7/504 104/18722 0.0222988595187521 0.113432174670985 ITGB1/ACTB/ATP2B4/SPTBN1/RHOQ/PIK3R1/RAB11FIP2 7 GO:0050808 synapse organization 19/504 426/18722 0.0224968558193102 0.114218205986396 SPARC/MAP1B/SPARCL1/FLNA/COL4A1/NFIA/TUBA1A/FARP1/PDLIM5/MEF2C/ACTB/PLXND1/LAMB2/ACTN1/ITSN1/CTBP2/NPTN/PTEN/ACTG1 19 GO:1903670 regulation of sprouting angiogenesis 5/504 60/18722 0.0225068404962662 0.114218205986396 THBS1/ADAMTS9/TJP1/JAK1/EPN2 5 GO:0048015 phosphatidylinositol-mediated signaling 10/504 178/18722 0.0225844186874422 0.114475944307759 DCN/PDGFRB/PDGFRA/HGF/TGFB2/FGFR1/ZFP36L1/PDGFA/PIK3R1/PTEN 10 GO:0045787 positive regulation of cell cycle 15/504 313/18722 0.0229632657878824 0.116017289927602 PDGFRB/TGFB2/CCND2/HSPA2/IGF2/DYNLT3/PKD2/CITED2/SVIL/EIF4EBP1/KMT2E/ADAMTS1/ROCK2/ATRX/PBX1 15 GO:0032103 positive regulation of response to external stimulus 19/504 427/18722 0.0229793938620397 0.116017289927602 PLA2G2A/THBS1/PDGFRB/AGTR1/RARRES2/SEMA5A/FLNA/GAS6/OSMR/FGFR1/CD81/MDK/TMSB4X/ETS1/IL6ST/IFI16/HSPB1/CLOCK/BMPR2 19 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 3/504 23/18722 0.0230201389772042 0.116017289927602 APOD/MYOCD/HIP1 3 GO:0035988 chondrocyte proliferation 3/504 23/18722 0.0230201389772042 0.116017289927602 DDR2/EXT1/BMPR2 3 GO:0045165 cell fate commitment 13/504 258/18722 0.0230242597375629 0.116017289927602 TGFB1I1/TBX2/WNT2/JAG1/GAS1/NR2F2/MEF2C/ITGB1/EXT1/SOX6/SMAD5/NOTCH2/STAT3 13 GO:0001892 embryonic placenta development 6/504 82/18722 0.0231747894029913 0.116501029551744 WNT2/NR2F2/IGF2/PKD2/CITED2/ZFP36L1 6 GO:0008543 fibroblast growth factor receptor signaling pathway 6/504 82/18722 0.0231747894029913 0.116501029551744 THBS1/SULF2/FGFR1/EXT1/SPRY1/NPTN 6 GO:0007346 regulation of mitotic cell cycle 20/504 457/18722 0.0233893843076214 0.117441644120407 PDGFRB/FHL1/KANK2/CCND2/GAS1/HSPA2/SOX4/TIMP2/IGF2/DYNLT3/CAV2/PKD2/ZFP36L1/EIF4EBP1/KMT2E/ADAMTS1/PTEN/PBX1/TAOK1/NBN 20 GO:0060249 anatomical structure homeostasis 15/504 314/18722 0.0235436946819902 0.118077708187962 LAMA2/CTSK/VCL/ITGB1/EXT1/LAMC1/ACTB/TJP1/B2M/CFL2/HSPB1/WWTR1/TAOK1/AKT3/ACTG1 15 GO:0032271 regulation of protein polymerization 12/504 232/18722 0.0236849413925034 0.118646840058812 MAP1B/LMOD1/ELN/MYADM/TMSB4X/EPS8/SPTBN1/GSN/CDC42EP3/NCKAP1/SVIL/ARL3 12 GO:0050770 regulation of axonogenesis 9/504 154/18722 0.0237268411560836 0.118717555339514 THY1/MAP1B/SEMA5A/CHN1/METRN/PLXND1/MACF1/PTEN/BMPR2 9 GO:0071470 cellular response to osmotic stress 4/504 41/18722 0.0239573730459488 0.11973082459104 MYLK/TSPO/PKD2/ZFP36L1 4 GO:0071384 cellular response to corticosteroid stimulus 5/504 61/18722 0.0239924495166869 0.119766047645798 FOXO1/NR3C1/ZFP36L1/ZFP36/FBXO32 5 GO:0008016 regulation of heart contraction 11/504 206/18722 0.0241062017484736 0.120193465660709 GJC1/FXYD1/TBX2/FLNA/TPM1/TGFB2/SLC8A1/ATP2B4/CAV1/CALM2/MEF2A 11 GO:0043409 negative regulation of MAPK cascade 10/504 180/18722 0.0241739520687097 0.120390789265264 EMILIN1/CAMK2N1/FOXO1/CAV1/SPRY1/TIMP3/ZMYND11/AIDA/ATF3/PTEN 10 GO:0046620 regulation of organ growth 7/504 106/18722 0.0244535633751983 0.121358973637889 TBX2/WNT2/MEIS1/MEF2C/IGF2/CITED2/PTEN 7 GO:0046822 regulation of nucleocytoplasmic transport 7/504 106/18722 0.0244535633751983 0.121358973637889 APOD/FLNA/GAS6/IFI27/PKIG/PIK3R1/PPP1R12A 7 GO:1905477 positive regulation of protein localization to membrane 7/504 106/18722 0.0244535633751983 0.121358973637889 CD81/ITGB1/ATP2B4/SPTBN1/PIK3R1/STOM/RAB11FIP2 7 GO:0032640 tumor necrosis factor production 10/504 181/18722 0.0249982692907678 0.123774744703883 THBS1/SPON2/AKAP12/GAS6/AXL/TSPO/HSPB1/ZFP36/STAT3/PIK3R1 10 GO:0032680 regulation of tumor necrosis factor production 10/504 181/18722 0.0249982692907678 0.123774744703883 THBS1/SPON2/AKAP12/GAS6/AXL/TSPO/HSPB1/ZFP36/STAT3/PIK3R1 10 GO:0030098 lymphocyte differentiation 17/504 374/18722 0.0254627335042128 0.125872616912234 GAS6/AXL/LGALS1/ITGB1/MDK/KLF6/SOX4/EGR1/B2M/ZFP36L1/NOTCH2/XBP1/STAT3/PIK3R1/ZMIZ1/PBX1/SOS1 17 GO:0009267 cellular response to starvation 9/504 156/18722 0.0255251761697953 0.125872616912234 GAS6/FOXO1/SLC38A2/IFI16/MAP1LC3A/JUN/XBP1/ATF3/BMPR2 9 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 5/504 62/18722 0.0255397984701396 0.125872616912234 EMILIN1/TGFB2/TWSG1/RBPMS/BMPR2 5 GO:1903078 positive regulation of protein localization to plasma membrane 5/504 62/18722 0.0255397984701396 0.125872616912234 ITGB1/ATP2B4/SPTBN1/PIK3R1/RAB11FIP2 5 GO:0002573 myeloid leukocyte differentiation 11/504 208/18722 0.0256477011438975 0.125923321439451 GPC3/CD81/MYH9/SH3PXD2A/FBN1/CITED2/ZFP36L1/NOTCH2/IFI16/JUN/PIK3R1 11 GO:0001779 natural killer cell differentiation 3/504 24/18722 0.0257952519577849 0.125923321439451 GAS6/AXL/PBX1 3 GO:0002726 positive regulation of T cell cytokine production 3/504 24/18722 0.0257952519577849 0.125923321439451 CD81/IL1R1/B2M 3 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 3/504 24/18722 0.0257952519577849 0.125923321439451 THBS1/SULF2/SPRY1 3 GO:0060149 negative regulation of posttranscriptional gene silencing 3/504 24/18722 0.0257952519577849 0.125923321439451 KCNQ1OT1/NCOR2/STAT3 3 GO:0060561 apoptotic process involved in morphogenesis 3/504 24/18722 0.0257952519577849 0.125923321439451 CRYAB/HAND2/TGFB2 3 GO:0060967 negative regulation of gene silencing by RNA 3/504 24/18722 0.0257952519577849 0.125923321439451 KCNQ1OT1/NCOR2/STAT3 3 GO:0098743 cell aggregation 3/504 24/18722 0.0257952519577849 0.125923321439451 MGP/SOX6/BMP1 3 GO:0048017 inositol lipid-mediated signaling 10/504 182/18722 0.0258426073498756 0.125923321439451 DCN/PDGFRB/PDGFRA/HGF/TGFB2/FGFR1/ZFP36L1/PDGFA/PIK3R1/PTEN 10 GO:0030574 collagen catabolic process 4/504 42/18722 0.0259331904672869 0.125923321439451 ADAMTS2/CTSK/MMP2/ITGB1 4 GO:0033574 response to testosterone 4/504 42/18722 0.0259331904672869 0.125923321439451 THBS1/TSPO/ROCK2/MSN 4 GO:0045773 positive regulation of axon extension 4/504 42/18722 0.0259331904672869 0.125923321439451 MAP1B/SEMA5A/MACF1/BMPR2 4 GO:2001222 regulation of neuron migration 4/504 42/18722 0.0259331904672869 0.125923321439451 COL3A1/FLNA/MDK/STAT3 4 GO:0018108 peptidyl-tyrosine phosphorylation 17/504 375/18722 0.0260358160835736 0.126278140891158 PDGFRB/THY1/DDR2/PDGFRA/HGF/GAS6/AXL/PEAK1/FGFR1/CD81/IL6ST/DYRK2/CAV1/IGF2/HIPK2/JAK1/PDGFA 17 GO:0071222 cellular response to lipopolysaccharide 11/504 209/18722 0.0264446937288938 0.127898316695916 SPON2/AXL/TFPI/VIM/MTDH/MEF2C/EDNRB/TSPO/ZFP36/ADAM9/XBP1 11 GO:1902107 positive regulation of leukocyte differentiation 9/504 157/18722 0.0264596564379101 0.127898316695916 GAS6/AXL/MDK/SOX4/ZFP36L1/NOTCH2/JUN/XBP1/ZMIZ1 9 GO:1903708 positive regulation of hemopoiesis 9/504 157/18722 0.0264596564379101 0.127898316695916 GAS6/AXL/MDK/SOX4/ZFP36L1/NOTCH2/JUN/XBP1/ZMIZ1 9 GO:0002832 negative regulation of response to biotic stimulus 7/504 108/18722 0.0267470360550498 0.129141339054495 A2M/SERPING1/IFI16/HTRA1/ISG15/AHR/STAT2 7 GO:0032092 positive regulation of protein binding 6/504 85/18722 0.0270874287915512 0.1306068998464 CTHRC1/RAMP1/CAV1/B2M/PLXND1/HIPK2 6 GO:0032868 response to insulin 13/504 264/18722 0.0271117060996388 0.1306068998464 RARRES2/ENPP1/FOXO1/RHOQ/EGR1/IGF2/CAV2/ZFP36L1/XBP1/PIK3R1/PTEN/PTPRA/EIF4EBP2 13 GO:0002685 regulation of leukocyte migration 11/504 210/18722 0.0272594458055308 0.131170734152065 THBS1/THY1/RARRES2/APOD/EMILIN1/GAS6/CD81/MDK/IL1R1/MSN/CD99 11 GO:0007389 pattern specification process 19/504 436/18722 0.0276860632418303 0.133032673245227 TBX2/HES4/HAND2/WNT2/MEIS1/NR2F2/GPC3/MEF2C/EXT1/TSHZ1/SPRY1/PKD2/CITED2/HIPK2/SMAD5/NOTCH2/AIDA/BMPR2/PBX1 19 GO:0018212 peptidyl-tyrosine modification 17/504 378/18722 0.027813338144059 0.133032673245227 PDGFRB/THY1/DDR2/PDGFRA/HGF/GAS6/AXL/PEAK1/FGFR1/CD81/IL6ST/DYRK2/CAV1/IGF2/HIPK2/JAK1/PDGFA 17 GO:0001709 cell fate determination 4/504 43/18722 0.0280040397922703 0.133032673245227 TBX2/JAG1/MEF2C/NOTCH2 4 GO:0003183 mitral valve morphogenesis 2/504 10/18722 0.0282067872595778 0.133032673245227 SOX4/BMPR2 2 GO:0007028 cytoplasm organization 2/504 10/18722 0.0282067872595778 0.133032673245227 ZMIZ1/SOS1 2 GO:0019062 virion attachment to host cell 2/504 10/18722 0.0282067872595778 0.133032673245227 GAS6/CD81 2 GO:0036363 transforming growth factor beta activation 2/504 10/18722 0.0282067872595778 0.133032673245227 LRRC32/LTBP1 2 GO:0042989 sequestering of actin monomers 2/504 10/18722 0.0282067872595778 0.133032673245227 TMSB4X/GSN 2 GO:0044557 relaxation of smooth muscle 2/504 10/18722 0.0282067872595778 0.133032673245227 PRKG1/SLC8A1 2 GO:0050861 positive regulation of B cell receptor signaling pathway 2/504 10/18722 0.0282067872595778 0.133032673245227 CD81/CMTM3 2 GO:0072070 loop of Henle development 2/504 10/18722 0.0282067872595778 0.133032673245227 JAG1/PKD2 2 GO:0097084 vascular associated smooth muscle cell development 2/504 10/18722 0.0282067872595778 0.133032673245227 EFEMP2/SGCB 2 GO:0097250 mitochondrial respirasome assembly 2/504 10/18722 0.0282067872595778 0.133032673245227 HIGD1B/COX7A1 2 GO:0098903 regulation of membrane repolarization during action potential 2/504 10/18722 0.0282067872595778 0.133032673245227 FLNA/CAV1 2 GO:1902946 protein localization to early endosome 2/504 10/18722 0.0282067872595778 0.133032673245227 ROCK2/MSN 2 GO:1905651 regulation of artery morphogenesis 2/504 10/18722 0.0282067872595778 0.133032673245227 MDK/AKT3 2 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation 2/504 10/18722 0.0282067872595778 0.133032673245227 ATP2B4/NCOA7 2 GO:2001223 negative regulation of neuron migration 2/504 10/18722 0.0282067872595778 0.133032673245227 COL3A1/STAT3 2 GO:0014031 mesenchymal cell development 6/504 86/18722 0.0284829669013265 0.133597933665607 SEMA5A/EDNRA/HAND2/JAG1/EDNRB/CITED2 6 GO:0048864 stem cell development 6/504 86/18722 0.0284829669013265 0.133597933665607 SEMA5A/EDNRA/HAND2/JAG1/EDNRB/CITED2 6 GO:0060761 negative regulation of response to cytokine stimulus 6/504 86/18722 0.0284829669013265 0.133597933665607 PXDN/SLIT3/GAS6/CAV1/ISG15/STAT2 6 GO:1903510 mucopolysaccharide metabolic process 6/504 86/18722 0.0284829669013265 0.133597933665607 DCN/HGF/BGN/EXT1/DSEL/UGDH 6 GO:2000117 negative regulation of cysteine-type endopeptidase activity 6/504 86/18722 0.0284829669013265 0.133597933665607 THBS1/CRYAB/HGF/GAS6/IFI16/NR4A1 6 GO:0001819 positive regulation of cytokine production 20/504 467/18722 0.0285327398975875 0.13363717274888 LUM/THBS1/SPON2/AKAP12/HGF/SULF2/CD81/MDK/IL1R1/IL6ST/SPTBN1/EGR1/B2M/IFI16/HSPB1/ISG15/ROCK2/XBP1/STAT3/PIK3R1 20 GO:0003094 glomerular filtration 3/504 25/18722 0.0287415309516079 0.13363717274888 MCAM/GAS6/SULF2 3 GO:0048596 embryonic camera-type eye morphogenesis 3/504 25/18722 0.0287415309516079 0.13363717274888 TBX2/CITED2/HIPK2 3 GO:0062009 secondary palate development 3/504 25/18722 0.0287415309516079 0.13363717274888 LRRC32/TGFB2/TSHZ1 3 GO:0072207 metanephric epithelium development 3/504 25/18722 0.0287415309516079 0.13363717274888 LAMB2/PKD2/WWTR1 3 GO:1903055 positive regulation of extracellular matrix organization 3/504 25/18722 0.0287415309516079 0.13363717274888 DDR2/EFEMP2/EMILIN1 3 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 3/504 25/18722 0.0287415309516079 0.13363717274888 MYOCD/NCOR2/STAT3 3 GO:1904385 cellular response to angiotensin 3/504 25/18722 0.0287415309516079 0.13363717274888 AGTR1/CAV1/ROCK2 3 GO:0006940 regulation of smooth muscle contraction 5/504 64/18722 0.0288226293115553 0.133723230236999 CNN1/PRKG1/MYOCD/ARHGAP42/CAV1 5 GO:0032507 maintenance of protein location in cell 5/504 64/18722 0.0288226293115553 0.133723230236999 TMSB4X/SYNE1/CAV1/GSN/TSPO 5 GO:1904659 glucose transmembrane transport 7/504 110/18722 0.0291827852808113 0.135247333519422 EDNRA/ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 7 GO:0071706 tumor necrosis factor superfamily cytokine production 10/504 186/18722 0.029424845583913 0.136073988290109 THBS1/SPON2/AKAP12/GAS6/AXL/TSPO/HSPB1/ZFP36/STAT3/PIK3R1 10 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 10/504 186/18722 0.029424845583913 0.136073988290109 THBS1/SPON2/AKAP12/GAS6/AXL/TSPO/HSPB1/ZFP36/STAT3/PIK3R1 10 GO:0001894 tissue homeostasis 13/504 268/18722 0.0301174117561166 0.13877182840455 LAMA2/CTSK/VCL/ITGB1/EXT1/LAMC1/ACTB/TJP1/B2M/HSPB1/WWTR1/AKT3/ACTG1 13 GO:0030521 androgen receptor signaling pathway 4/504 44/18722 0.0301706128218644 0.13877182840455 PLPP1/NCOR2/DDX17/ZMIZ1 4 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 4/504 44/18722 0.0301706128218644 0.13877182840455 PTK7/FAT1/MSN/MYO9A 4 GO:0046006 regulation of activated T cell proliferation 4/504 44/18722 0.0301706128218644 0.13877182840455 IGFBP2/LRRC32/IGF2/PRKAR1A 4 GO:0048066 developmental pigmentation 4/504 44/18722 0.0301706128218644 0.13877182840455 ENPP1/ZEB2/MEF2C/EDNRB 4 GO:0031346 positive regulation of cell projection organization 16/504 353/18722 0.0302494191973114 0.138984697021625 MAP1B/SEMA5A/HGF/FLNA/METRN/MDK/EPS8/RHOQ/PTK7/PLXND1/CDC42EP3/NCKAP1/PIK3R1/MACF1/NPTN/BMPR2 16 GO:0060389 pathway-restricted SMAD protein phosphorylation 5/504 65/18722 0.030559436713207 0.139957634593284 EMILIN1/TGFB2/TWSG1/RBPMS/BMPR2 5 GO:0072577 endothelial cell apoptotic process 5/504 65/18722 0.030559436713207 0.139957634593284 THBS1/CD248/SEMA5A/GAS6/BMPR2 5 GO:1905330 regulation of morphogenesis of an epithelium 5/504 65/18722 0.030559436713207 0.139957634593284 TBX2/WNT2/HGF/MDK/PDGFA 5 GO:0043401 steroid hormone mediated signaling pathway 8/504 136/18722 0.0309059130053093 0.141392897507159 PLPP1/KANK2/NR3C1/NCOR2/DDX17/CLOCK/RBFOX2/ZMIZ1 8 GO:0007601 visual perception 11/504 215/18722 0.0316063441291181 0.144288363743292 COL1A1/LUM/GJC1/LAMC3/COL18A1/TIMP3/LAMB2/TGFBI/MYO9A/CHM/DHRS3 11 GO:0031669 cellular response to nutrient levels 11/504 215/18722 0.0316063441291181 0.144288363743292 COL1A1/GAS6/KANK2/FOXO1/SLC38A2/IFI16/MAP1LC3A/JUN/XBP1/ATF3/BMPR2 11 GO:0002026 regulation of the force of heart contraction 3/504 26/18722 0.031858195364848 0.144358503493102 SLC8A1/ATP2B4/CAV1 3 GO:0003416 endochondral bone growth 3/504 26/18722 0.031858195364848 0.144358503493102 DDR2/COL27A1/EXT1 3 GO:0051016 barbed-end actin filament capping 3/504 26/18722 0.031858195364848 0.144358503493102 EPS8/GSN/SVIL 3 GO:0070102 interleukin-6-mediated signaling pathway 3/504 26/18722 0.031858195364848 0.144358503493102 IL6ST/JAK1/STAT3 3 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 3/504 26/18722 0.031858195364848 0.144358503493102 MYOCD/NCOR2/STAT3 3 GO:0097205 renal filtration 3/504 26/18722 0.031858195364848 0.144358503493102 MCAM/GAS6/SULF2 3 GO:1905523 positive regulation of macrophage migration 3/504 26/18722 0.031858195364848 0.144358503493102 THBS1/RARRES2/MDK 3 GO:0060048 cardiac muscle contraction 8/504 137/18722 0.0320837081113884 0.145226360974537 GJC1/FLNA/TPM1/SLC8A1/CAV1/GSN/SMAD5/CALM2 8 GO:0003254 regulation of membrane depolarization 4/504 45/18722 0.0324334738366573 0.146344491767726 DCN/FHL1/SLMAP/TSPO 4 GO:0022602 ovulation cycle process 4/504 45/18722 0.0324334738366573 0.146344491767726 SLIT3/PDGFRA/TGFB2/ADAMTS1 4 GO:0031670 cellular response to nutrient 4/504 45/18722 0.0324334738366573 0.146344491767726 COL1A1/GAS6/KANK2/XBP1 4 GO:0030041 actin filament polymerization 10/504 190/18722 0.0333457013939774 0.147830107608706 LMOD1/ELN/MYADM/TMSB4X/EPS8/SPTBN1/GSN/CDC42EP3/NCKAP1/SVIL 10 GO:0070374 positive regulation of ERK1 and ERK2 cascade 11/504 217/18722 0.0334760550607537 0.147830107608706 PLA2G2A/PDGFRB/AKAP12/HAND2/PDGFRA/GAS6/FERMT2/NOTCH2/PDGFA/NPTN/PTEN 11 GO:0001765 membrane raft assembly 2/504 11/18722 0.0338698046685988 0.147830107608706 CAV1/CAV2 2 GO:0001867 complement activation, lectin pathway 2/504 11/18722 0.0338698046685988 0.147830107608706 A2M/SERPING1 2 GO:0001967 suckling behavior 2/504 11/18722 0.0338698046685988 0.147830107608706 HAND2/GLS 2 GO:0003174 mitral valve development 2/504 11/18722 0.0338698046685988 0.147830107608706 SOX4/BMPR2 2 GO:0006527 arginine catabolic process 2/504 11/18722 0.0338698046685988 0.147830107608706 ATP2B4/DDAH2 2 GO:0006971 hypotonic response 2/504 11/18722 0.0338698046685988 0.147830107608706 MYLK/TSPO 2 GO:0014820 tonic smooth muscle contraction 2/504 11/18722 0.0338698046685988 0.147830107608706 MYLK/EDNRA 2 GO:0033327 Leydig cell differentiation 2/504 11/18722 0.0338698046685988 0.147830107608706 PDGFRA/MGST1 2 GO:0034350 regulation of glial cell apoptotic process 2/504 11/18722 0.0338698046685988 0.147830107608706 AKAP12/GAS6 2 GO:0035457 cellular response to interferon-alpha 2/504 11/18722 0.0338698046685988 0.147830107608706 GAS6/AXL 2 GO:0035581 sequestering of extracellular ligand from receptor 2/504 11/18722 0.0338698046685988 0.147830107608706 LTBP1/FBN1 2 GO:0042789 mRNA transcription by RNA polymerase II 2/504 11/18722 0.0338698046685988 0.147830107608706 FLNA/STAT3 2 GO:0043589 skin morphogenesis 2/504 11/18722 0.0338698046685988 0.147830107608706 COL1A2/COL1A1 2 GO:0045657 positive regulation of monocyte differentiation 2/504 11/18722 0.0338698046685988 0.147830107608706 ZFP36L1/JUN 2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 2/504 11/18722 0.0338698046685988 0.147830107608706 PKD2/CALM2 2 GO:0060379 cardiac muscle cell myoblast differentiation 2/504 11/18722 0.0338698046685988 0.147830107608706 TBX2/MYOCD 2 GO:0061314 Notch signaling involved in heart development 2/504 11/18722 0.0338698046685988 0.147830107608706 JAG1/NOTCH2 2 GO:0071492 cellular response to UV-A 2/504 11/18722 0.0338698046685988 0.147830107608706 TIMP1/MMP2 2 GO:0072017 distal tubule development 2/504 11/18722 0.0338698046685988 0.147830107608706 JAG1/PKD2 2 GO:0072110 glomerular mesangial cell proliferation 2/504 11/18722 0.0338698046685988 0.147830107608706 PDGFRB/EGR1 2 GO:0072497 mesenchymal stem cell differentiation 2/504 11/18722 0.0338698046685988 0.147830107608706 PDGFRA/SOX6 2 GO:0097048 dendritic cell apoptotic process 2/504 11/18722 0.0338698046685988 0.147830107608706 GAS6/AXL 2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 2/504 11/18722 0.0338698046685988 0.147830107608706 CAV1/CALM2 2 GO:1904181 positive regulation of membrane depolarization 2/504 11/18722 0.0338698046685988 0.147830107608706 DCN/TSPO 2 GO:1904321 response to forskolin 2/504 11/18722 0.0338698046685988 0.147830107608706 ADCY3/AHR 2 GO:1904322 cellular response to forskolin 2/504 11/18722 0.0338698046685988 0.147830107608706 ADCY3/AHR 2 GO:1905050 positive regulation of metallopeptidase activity 2/504 11/18722 0.0338698046685988 0.147830107608706 ANTXR1/STAT3 2 GO:1905668 positive regulation of protein localization to endosome 2/504 11/18722 0.0338698046685988 0.147830107608706 ROCK2/MSN 2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity 2/504 11/18722 0.0338698046685988 0.147830107608706 PKIG/PRKAR1A 2 GO:2000668 regulation of dendritic cell apoptotic process 2/504 11/18722 0.0338698046685988 0.147830107608706 GAS6/AXL 2 GO:1903317 regulation of protein maturation 5/504 67/18722 0.0342267527874889 0.149235627205041 THBS1/GAS1/SOX4/MYH9/GSN 5 GO:0008645 hexose transmembrane transport 7/504 114/18722 0.034494031017324 0.149969395423559 EDNRA/ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 7 GO:0030216 keratinocyte differentiation 8/504 139/18722 0.0345304742435828 0.149969395423559 TXNIP/JAG1/PALLD/ZFP36L1/ZFP36/ROCK2/ADAM9/FOSL2 8 GO:0002028 regulation of sodium ion transport 6/504 90/18722 0.0345354282931856 0.149969395423559 FXYD1/SLMAP/SLC8A1/ATP2B4/ACTN4/STOM 6 GO:0046849 bone remodeling 6/504 90/18722 0.0345354282931856 0.149969395423559 CTHRC1/CTSK/MDK/EXT1/P3H4/NOTCH2 6 GO:0010828 positive regulation of glucose transmembrane transport 4/504 46/18722 0.0347930619090317 0.150781697299485 GPC3/RHOQ/MEF2A/PIK3R1 4 GO:0043616 keratinocyte proliferation 4/504 46/18722 0.0347930619090317 0.150781697299485 MDK/ZFP36L1/NOTCH2/ZFP36 4 GO:0071216 cellular response to biotic stimulus 12/504 246/18722 0.0349673304027638 0.151381811702159 SPON2/AXL/TFPI/VIM/TXNIP/MTDH/MEF2C/EDNRB/TSPO/ZFP36/ADAM9/XBP1 12 GO:0001958 endochondral ossification 3/504 27/18722 0.0351441041910932 0.151381811702159 COL1A1/MEF2C/EXT1 3 GO:0010758 regulation of macrophage chemotaxis 3/504 27/18722 0.0351441041910932 0.151381811702159 THBS1/RARRES2/MDK 3 GO:0035459 vesicle cargo loading 3/504 27/18722 0.0351441041910932 0.151381811702159 SEC31A/SEC23A/SEC24D 3 GO:0036075 replacement ossification 3/504 27/18722 0.0351441041910932 0.151381811702159 COL1A1/MEF2C/EXT1 3 GO:1903319 positive regulation of protein maturation 3/504 27/18722 0.0351441041910932 0.151381811702159 SOX4/MYH9/GSN 3 GO:0050953 sensory perception of light stimulus 11/504 219/18722 0.0354227523142915 0.152428419576 COL1A1/LUM/GJC1/LAMC3/COL18A1/TIMP3/LAMB2/TGFBI/MYO9A/CHM/DHRS3 11 GO:0051148 negative regulation of muscle cell differentiation 5/504 68/18722 0.0361582690257035 0.155012576174068 MYOCD/SOX6/IGF2/XBP1/BMPR2 5 GO:1902305 regulation of sodium ion transmembrane transport 5/504 68/18722 0.0361582690257035 0.155012576174068 FXYD1/SLMAP/ATP2B4/ACTN4/STOM 5 GO:0019935 cyclic-nucleotide-mediated signaling 6/504 91/18722 0.036168391866498 0.155012576174068 THBS1/PRKG1/PDE3A/EDNRB/EIF4EBP2/AHR 6 GO:0060191 regulation of lipase activity 6/504 91/18722 0.036168391866498 0.155012576174068 PDGFRB/AGTR1/EDNRA/PDGFRA/LPAR1/FGFR1 6 GO:0044706 multi-multicellular organism process 11/504 220/18722 0.0364254012194205 0.155957654720024 IGFBP7/IGFBP5/IGFBP2/TIMP1/MMP2/NR2F2/ETS1/SLC38A2/CITED2/VMP1/BMPR2 11 GO:0010712 regulation of collagen metabolic process 4/504 47/18722 0.0372496934134125 0.157967435873976 PDGFRB/EMILIN1/VIM/ITGB1 4 GO:0014911 positive regulation of smooth muscle cell migration 4/504 47/18722 0.0372496934134125 0.157967435873976 IGFBP5/PDGFRB/MDK/ADAMTS1 4 GO:0042311 vasodilation 4/504 47/18722 0.0372496934134125 0.157967435873976 ITGA1/PRKG1/EXT1/EDNRB 4 GO:0043114 regulation of vascular permeability 4/504 47/18722 0.0372496934134125 0.157967435873976 AKAP12/PDE3A/TJP1/FERMT2 4 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 4/504 47/18722 0.0372496934134125 0.157967435873976 EGR1/CITED2/JUN/ATF3 4 GO:0046677 response to antibiotic 4/504 47/18722 0.0372496934134125 0.157967435873976 AOC3/MEF2C/CRIP1/JAK1 4 GO:0048483 autonomic nervous system development 4/504 47/18722 0.0372496934134125 0.157967435873976 EDNRA/HAND2/EDNRB/SOX4 4 GO:0050798 activated T cell proliferation 4/504 47/18722 0.0372496934134125 0.157967435873976 IGFBP2/LRRC32/IGF2/PRKAR1A 4 GO:0015749 monosaccharide transmembrane transport 7/504 116/18722 0.0373753984714697 0.157967435873976 EDNRA/ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 7 GO:0021782 glial cell development 7/504 116/18722 0.0373753984714697 0.157967435873976 LAMC3/MXRA8/VIM/MDK/SOX4/LAMB2/PTEN 7 GO:0030326 embryonic limb morphogenesis 7/504 116/18722 0.0373753984714697 0.157967435873976 TBX2/HAND2/TGFB2/GPC3/NOTCH2/MBNL1/PBX1 7 GO:0035113 embryonic appendage morphogenesis 7/504 116/18722 0.0373753984714697 0.157967435873976 TBX2/HAND2/TGFB2/GPC3/NOTCH2/MBNL1/PBX1 7 GO:1990748 cellular detoxification 7/504 116/18722 0.0373753984714697 0.157967435873976 PXDN/NXN/FBLN5/MGST1/GPX8/GSTM3/SOD3 7 GO:0071219 cellular response to molecule of bacterial origin 11/504 221/18722 0.0374478067532218 0.158117073376005 SPON2/AXL/TFPI/VIM/MTDH/MEF2C/EDNRB/TSPO/ZFP36/ADAM9/XBP1 11 GO:1902806 regulation of cell cycle G1/S phase transition 9/504 168/18722 0.0383757856213592 0.161378011839508 FHL1/KANK2/CCND2/SOX4/ATP2B4/PKD2/KMT2E/ADAMTS1/PTEN 9 GO:0050729 positive regulation of inflammatory response 8/504 142/18722 0.0384328302532314 0.161378011839508 PLA2G2A/AGTR1/OSMR/CD81/MDK/ETS1/IL6ST/CLOCK 8 GO:2000045 regulation of G1/S transition of mitotic cell cycle 8/504 142/18722 0.0384328302532314 0.161378011839508 FHL1/KANK2/CCND2/SOX4/PKD2/KMT2E/ADAMTS1/PTEN 8 GO:0002313 mature B cell differentiation involved in immune response 3/504 28/18722 0.0385977833138256 0.161378011839508 LGALS1/NOTCH2/XBP1 3 GO:0003156 regulation of animal organ formation 3/504 28/18722 0.0385977833138256 0.161378011839508 WNT2/SPRY1/CITED2 3 GO:0009065 glutamine family amino acid catabolic process 3/504 28/18722 0.0385977833138256 0.161378011839508 ATP2B4/DDAH2/GLS 3 GO:0010464 regulation of mesenchymal cell proliferation 3/504 28/18722 0.0385977833138256 0.161378011839508 WNT2/NFIB/PDGFA 3 GO:1902624 positive regulation of neutrophil migration 3/504 28/18722 0.0385977833138256 0.161378011839508 MDK/IL1R1/CD99 3 GO:1903671 negative regulation of sprouting angiogenesis 3/504 28/18722 0.0385977833138256 0.161378011839508 THBS1/ADAMTS9/EPN2 3 GO:1990776 response to angiotensin 3/504 28/18722 0.0385977833138256 0.161378011839508 AGTR1/CAV1/ROCK2 3 GO:0044772 mitotic cell cycle phase transition 18/504 424/18722 0.0391379957270228 0.161734048609314 FHL1/KANK2/CCND2/ITGB1/HSPA2/SOX4/EPS8/PKD2/ZFP36L1/CALM2/EIF4EBP1/KMT2E/ADAMTS1/PTEN/PBX1/TAOK1/NBN/CCNG2 18 GO:0033273 response to vitamin 6/504 93/18722 0.0395809387420418 0.161734048609314 COL1A1/SPARC/MAP1B/GAS6/KANK2/TSPO 6 GO:0060993 kidney morphogenesis 6/504 93/18722 0.0395809387420418 0.161734048609314 PDGFRB/GPC3/SOX4/PKD2/WWTR1/PBX1 6 GO:0002328 pro-B cell differentiation 2/504 12/18722 0.0399319965557749 0.161734048609314 SOX4/SOS1 2 GO:0009886 post-embryonic animal morphogenesis 2/504 12/18722 0.0399319965557749 0.161734048609314 FBN1/ATRX 2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 2/504 12/18722 0.0399319965557749 0.161734048609314 APOD/MYOCD 2 GO:0014889 muscle atrophy 2/504 12/18722 0.0399319965557749 0.161734048609314 GATM/GSN 2 GO:0031953 negative regulation of protein autophosphorylation 2/504 12/18722 0.0399319965557749 0.161734048609314 ENPP1/CAV1 2 GO:0032823 regulation of natural killer cell differentiation 2/504 12/18722 0.0399319965557749 0.161734048609314 GAS6/AXL 2 GO:0032908 regulation of transforming growth factor beta1 production 2/504 12/18722 0.0399319965557749 0.161734048609314 LUM/THBS1 2 GO:0034333 adherens junction assembly 2/504 12/18722 0.0399319965557749 0.161734048609314 VCL/ACTB 2 GO:0035739 CD4-positive, alpha-beta T cell proliferation 2/504 12/18722 0.0399319965557749 0.161734048609314 TWSG1/CD81 2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 2/504 12/18722 0.0399319965557749 0.161734048609314 IGFBP5/IGFBP4 2 GO:0044650 adhesion of symbiont to host cell 2/504 12/18722 0.0399319965557749 0.161734048609314 GAS6/CD81 2 GO:0045602 negative regulation of endothelial cell differentiation 2/504 12/18722 0.0399319965557749 0.161734048609314 ZEB1/JAG1 2 GO:0045916 negative regulation of complement activation 2/504 12/18722 0.0399319965557749 0.161734048609314 A2M/SERPING1 2 GO:0048548 regulation of pinocytosis 2/504 12/18722 0.0399319965557749 0.161734048609314 AXL/CAV1 2 GO:0051001 negative regulation of nitric-oxide synthase activity 2/504 12/18722 0.0399319965557749 0.161734048609314 ATP2B4/CAV1 2 GO:0051549 positive regulation of keratinocyte migration 2/504 12/18722 0.0399319965557749 0.161734048609314 MAP4K4/ADAM9 2 GO:0051639 actin filament network formation 2/504 12/18722 0.0399319965557749 0.161734048609314 PLS3/ACTN1 2 GO:0061430 bone trabecula morphogenesis 2/504 12/18722 0.0399319965557749 0.161734048609314 COL1A1/MMP2 2 GO:0070572 positive regulation of neuron projection regeneration 2/504 12/18722 0.0399319965557749 0.161734048609314 HGF/FLNA 2 GO:0072537 fibroblast activation 2/504 12/18722 0.0399319965557749 0.161734048609314 PDGFRB/AKAP12 2 GO:0072584 caveolin-mediated endocytosis 2/504 12/18722 0.0399319965557749 0.161734048609314 CAV1/ITSN1 2 GO:0090177 establishment of planar polarity involved in neural tube closure 2/504 12/18722 0.0399319965557749 0.161734048609314 CTHRC1/PTK7 2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 2/504 12/18722 0.0399319965557749 0.161734048609314 CITED2/JUN 2 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 2/504 12/18722 0.0399319965557749 0.161734048609314 HSPA2/VMP1 2 GO:1903909 regulation of receptor clustering 2/504 12/18722 0.0399319965557749 0.161734048609314 CD81/GSN 2 GO:1905666 regulation of protein localization to endosome 2/504 12/18722 0.0399319965557749 0.161734048609314 ROCK2/MSN 2 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation 2/504 12/18722 0.0399319965557749 0.161734048609314 TWSG1/CD81 2 GO:2000727 positive regulation of cardiac muscle cell differentiation 2/504 12/18722 0.0399319965557749 0.161734048609314 MYOCD/MEF2C 2 GO:2001204 regulation of osteoclast development 2/504 12/18722 0.0399319965557749 0.161734048609314 FBN1/NOTCH2 2 GO:2001214 positive regulation of vasculogenesis 2/504 12/18722 0.0399319965557749 0.161734048609314 RRAS/RIN2 2 GO:0032386 regulation of intracellular transport 15/504 337/18722 0.0401431645690811 0.162435361935306 CRYAB/MAP1B/APOD/EHD2/FLNA/GAS6/IFI27/GAS1/CD81/PKIG/MSN/PIK3R1/STOM/PPP1R12A/TOMM7 15 GO:0060415 muscle tissue morphogenesis 5/504 70/18722 0.0402191379231489 0.16258881395044 MYLK/EFEMP2/WNT2/TPM1/TGFB2 5 GO:0030203 glycosaminoglycan metabolic process 7/504 118/18722 0.0404107661140045 0.162901135476548 DCN/PDGFRB/HGF/BGN/EXT1/DSEL/UGDH 7 GO:0034219 carbohydrate transmembrane transport 7/504 118/18722 0.0404107661140045 0.162901135476548 EDNRA/ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 7 GO:0051101 regulation of DNA binding 7/504 118/18722 0.0404107661140045 0.162901135476548 HAND2/MYOCD/TMSB4X/HIPK2/CALM2/IFI16/JUN 7 GO:0140694 non-membrane-bounded organelle assembly 16/504 367/18722 0.0408251884733392 0.164416616726276 MYH11/PDGFRB/LMOD1/PDGFRA/FLNA/TPM1/ITGB1/GSN/CFL2/CSRP1/MAP9/PRKAR1A/MEF2A/MSN/ACTG1/AKAP13 16 GO:0010952 positive regulation of peptidase activity 10/504 197/18722 0.0410622512359816 0.165215630443832 PCOLCE/ANTXR1/DLC1/UACA/HIP1/CAV1/GSN/IFI16/ROCK2/STAT3 10 GO:0002042 cell migration involved in sprouting angiogenesis 6/504 94/18722 0.0413612127681396 0.166105697517162 THBS1/ITGB1/HDAC7/STARD13/NR4A1/AKT3 6 GO:0030316 osteoclast differentiation 6/504 94/18722 0.0413612127681396 0.166105697517162 GPC3/CD81/SH3PXD2A/FBN1/NOTCH2/PIK3R1 6 GO:0043254 regulation of protein-containing complex assembly 18/504 427/18722 0.0414407574458681 0.166268879404877 CRYAB/MAP1B/LMOD1/ELN/MYADM/TMSB4X/EPS8/SPTBN1/GSN/CDC42EP3/FERMT2/NCKAP1/SVIL/EIF4EBP1/AIDA/ISG15/ARL3/MSN 18 GO:0005979 regulation of glycogen biosynthetic process 3/504 29/18722 0.0422174514093815 0.167197389977006 ENPP1/DYRK2/IGF2 3 GO:0010962 regulation of glucan biosynthetic process 3/504 29/18722 0.0422174514093815 0.167197389977006 ENPP1/DYRK2/IGF2 3 GO:0031069 hair follicle morphogenesis 3/504 29/18722 0.0422174514093815 0.167197389977006 IGFBP5/TGFB2/EXT1 3 GO:0048265 response to pain 3/504 29/18722 0.0422174514093815 0.167197389977006 THBS1/EDNRB/TSPO 3 GO:0060441 epithelial tube branching involved in lung morphogenesis 3/504 29/18722 0.0422174514093815 0.167197389977006 WNT2/EXT1/SPRY1 3 GO:0060969 negative regulation of gene silencing 3/504 29/18722 0.0422174514093815 0.167197389977006 KCNQ1OT1/NCOR2/STAT3 3 GO:0071549 cellular response to dexamethasone stimulus 3/504 29/18722 0.0422174514093815 0.167197389977006 FOXO1/NR3C1/FBXO32 3 GO:0090114 COPII-coated vesicle budding 3/504 29/18722 0.0422174514093815 0.167197389977006 SEC31A/SEC23A/SEC24D 3 GO:0098868 bone growth 3/504 29/18722 0.0422174514093815 0.167197389977006 DDR2/COL27A1/EXT1 3 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 3/504 29/18722 0.0422174514093815 0.167197389977006 DCN/ADGRA2/ATP2B4 3 GO:1903902 positive regulation of viral life cycle 3/504 29/18722 0.0422174514093815 0.167197389977006 AXL/LGALS1/CAV2 3 GO:0000281 mitotic cytokinesis 5/504 71/18722 0.0423491794157892 0.167197389977006 SPTBN1/MAP9/RHOB/ARL3/ROCK2 5 GO:0045824 negative regulation of innate immune response 5/504 71/18722 0.0423491794157892 0.167197389977006 A2M/SERPING1/IFI16/ISG15/STAT2 5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 4/504 49/18722 0.0424547550023523 0.167197389977006 TGFB2/TWSG1/RBPMS/BMPR2 4 GO:0030857 negative regulation of epithelial cell differentiation 4/504 49/18722 0.0424547550023523 0.167197389977006 ZEB1/JAG1/CAV1/SPRY1 4 GO:0035088 establishment or maintenance of apical/basal cell polarity 4/504 49/18722 0.0424547550023523 0.167197389977006 PTK7/FAT1/MSN/MYO9A 4 GO:0061245 establishment or maintenance of bipolar cell polarity 4/504 49/18722 0.0424547550023523 0.167197389977006 PTK7/FAT1/MSN/MYO9A 4 GO:0070169 positive regulation of biomineral tissue development 4/504 49/18722 0.0424547550023523 0.167197389977006 MEF2C/SLC8A1/ISG15/BMPR2 4 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 4/504 49/18722 0.0424547550023523 0.167197389977006 IGFBP5/MMP2/ADAMTS1/JUN 4 GO:1990928 response to amino acid starvation 4/504 49/18722 0.0424547550023523 0.167197389977006 SLC38A2/EIF4EBP1/MAP1LC3A/ATF3 4 GO:0071241 cellular response to inorganic substance 11/504 226/18722 0.0428617725202926 0.16864489316686 MT1E/FOXO1/MEF2C/B2M/TSPO/PKD2/MAP1LC3A/JUN/MEF2A/ATRX/SLC25A24 11 GO:0001678 cellular glucose homeostasis 9/504 172/18722 0.0434918810944532 0.170809566099815 CAMK2N1/GAS6/LGALS1/FOXO1/SOX4/MAP4K4/XBP1/PIK3R1/RAB11FIP2 9 GO:1990138 neuron projection extension 9/504 172/18722 0.0434918810944532 0.170809566099815 MAP1B/SLIT3/SEMA5A/VCL/ITGB1/LAMB2/DPYSL2/MACF1/BMPR2 9 GO:0032411 positive regulation of transporter activity 7/504 120/18722 0.0436024424453422 0.171086534957711 HSPA2/TMSB4X/ACTN4/PKD2/CALM2/VMP1/KMT2A 7 GO:0019932 second-messenger-mediated signaling 14/504 312/18722 0.0437942597109277 0.17168153371082 GUCY1A2/THBS1/AGTR1/PRKG1/PDE3A/LMCD1/SLC8A1/EDNRB/DYRK2/ATP2B4/DDAH2/CALM2/EIF4EBP2/AHR 14 GO:0034765 regulation of ion transmembrane transport 20/504 491/18722 0.0443146505358027 0.173562329733717 THY1/FXYD1/FHL1/FLNA/SLMAP/KCNK6/MEF2C/ITGB1/SLC8A1/HSPA2/TMSB4X/ATP2B4/CAV1/ACTN4/PKD2/CALM2/VMP1/AHNAK/PTEN/STOM 20 GO:0030032 lamellipodium assembly 5/504 72/18722 0.0445459968689631 0.17414917165698 VCL/ITGB1/ARHGEF6/NCKAP1/PIK3R1 5 GO:0033627 cell adhesion mediated by integrin 5/504 72/18722 0.0445459968689631 0.17414917165698 TGFB2/ITGB1/EXT1/FBN1/ADAM9 5 GO:0060425 lung morphogenesis 4/504 50/18722 0.0452032292878663 0.176074201227942 WNT2/NFIB/EXT1/SPRY1 4 GO:0060688 regulation of morphogenesis of a branching structure 4/504 50/18722 0.0452032292878663 0.176074201227942 WNT2/HGF/MDK/PDGFA 4 GO:0071709 membrane assembly 4/504 50/18722 0.0452032292878663 0.176074201227942 CAV1/SPTBN1/CAV2/PTEN 4 GO:0110151 positive regulation of biomineralization 4/504 50/18722 0.0452032292878663 0.176074201227942 MEF2C/SLC8A1/ISG15/BMPR2 4 GO:0045931 positive regulation of mitotic cell cycle 7/504 121/18722 0.0452575459316671 0.176115429293653 CCND2/HSPA2/DYNLT3/EIF4EBP1/KMT2E/ADAMTS1/PBX1 7 GO:0016331 morphogenesis of embryonic epithelium 8/504 147/18722 0.045573122588308 0.176115429293653 CTHRC1/TGFB1I1/WNT2/DLC1/TGFB2/SOX4/PTK7/CITED2 8 GO:0017145 stem cell division 3/504 30/18722 0.0460010445108519 0.176115429293653 TGFB2/EXT1/WWTR1 3 GO:0033137 negative regulation of peptidyl-serine phosphorylation 3/504 30/18722 0.0460010445108519 0.176115429293653 HGF/CAV1/PTEN 3 GO:0034368 protein-lipid complex remodeling 3/504 30/18722 0.0460010445108519 0.176115429293653 PLA2G2A/AGTR1/LIPG 3 GO:0034369 plasma lipoprotein particle remodeling 3/504 30/18722 0.0460010445108519 0.176115429293653 PLA2G2A/AGTR1/LIPG 3 GO:0044788 modulation by host of viral process 3/504 30/18722 0.0460010445108519 0.176115429293653 IFI27/CAV2/STOM 3 GO:0061311 cell surface receptor signaling pathway involved in heart development 3/504 30/18722 0.0460010445108519 0.176115429293653 HAND2/JAG1/NOTCH2 3 GO:0061384 heart trabecula morphogenesis 3/504 30/18722 0.0460010445108519 0.176115429293653 TGFB2/ADAMTS1/SOS1 3 GO:0070168 negative regulation of biomineral tissue development 3/504 30/18722 0.0460010445108519 0.176115429293653 ENPP1/GAS6/ROCK2 3 GO:0001768 establishment of T cell polarity 2/504 13/18722 0.0463678581688181 0.176115429293653 MYH9/GSN 2 GO:0001886 endothelial cell morphogenesis 2/504 13/18722 0.0463678581688181 0.176115429293653 COL18A1/COL15A1 2 GO:0003334 keratinocyte development 2/504 13/18722 0.0463678581688181 0.176115429293653 PALLD/FOSL2 2 GO:0008298 intracellular mRNA localization 2/504 13/18722 0.0463678581688181 0.176115429293653 ZFP36L1/ZFP36 2 GO:0032905 transforming growth factor beta1 production 2/504 13/18722 0.0463678581688181 0.176115429293653 LUM/THBS1 2 GO:0042308 negative regulation of protein import into nucleus 2/504 13/18722 0.0463678581688181 0.176115429293653 APOD/PKIG 2 GO:0044794 positive regulation by host of viral process 2/504 13/18722 0.0463678581688181 0.176115429293653 CAV2/STOM 2 GO:0048266 behavioral response to pain 2/504 13/18722 0.0463678581688181 0.176115429293653 THBS1/TSPO 2 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 2/504 13/18722 0.0463678581688181 0.176115429293653 PKD2/CALM2 2 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/504 13/18722 0.0463678581688181 0.176115429293653 ZFP36/TNRC6B 2 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 2/504 13/18722 0.0463678581688181 0.176115429293653 EGR1/CITED2 2 GO:0071801 regulation of podosome assembly 2/504 13/18722 0.0463678581688181 0.176115429293653 GSN/MSN 2 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response 2/504 13/18722 0.0463678581688181 0.176115429293653 XBP1/PIK3R1 2 GO:1900115 extracellular regulation of signal transduction 2/504 13/18722 0.0463678581688181 0.176115429293653 LTBP1/FBN1 2 GO:1900116 extracellular negative regulation of signal transduction 2/504 13/18722 0.0463678581688181 0.176115429293653 LTBP1/FBN1 2 GO:1902947 regulation of tau-protein kinase activity 2/504 13/18722 0.0463678581688181 0.176115429293653 HGF/EGR1 2 GO:1903054 negative regulation of extracellular matrix organization 2/504 13/18722 0.0463678581688181 0.176115429293653 ANTXR1/EMILIN1 2 GO:1904590 negative regulation of protein import 2/504 13/18722 0.0463678581688181 0.176115429293653 APOD/PKIG 2 GO:1904427 positive regulation of calcium ion transmembrane transport 5/504 73/18722 0.0468098032233744 0.177636136033285 THY1/HSPA2/PKD2/CALM2/VMP1 5 GO:0010656 negative regulation of muscle cell apoptotic process 4/504 51/18722 0.0480488414866051 0.181853586955061 HSPB6/HAND2/MYOCD/MDK 4 GO:0045661 regulation of myoblast differentiation 4/504 51/18722 0.0480488414866051 0.181853586955061 MYOCD/IGFBP3/MEF2C/ZFP36L1 4 GO:0051293 establishment of spindle localization 4/504 51/18722 0.0480488414866051 0.181853586955061 ITGB1/MYH9/SPRY1/MAP4 4 GO:0070301 cellular response to hydrogen peroxide 6/504 98/18722 0.0489824023145157 0.185222836362766 HGF/AXL/FOXO1/ETS1/RHOB/MAP1LC3A 6 GO:0030201 heparan sulfate proteoglycan metabolic process 3/504 31/18722 0.0499462392910203 0.187210772360114 SULF2/EXT1/UGDH 3 GO:0048384 retinoic acid receptor signaling pathway 3/504 31/18722 0.0499462392910203 0.187210772360114 ACTN4/CTBP2/DHRS3 3 GO:0048566 embryonic digestive tract development 3/504 31/18722 0.0499462392910203 0.187210772360114 RARRES2/PDGFRA/TGFB2 3 GO:0051569 regulation of histone H3-K4 methylation 3/504 31/18722 0.0499462392910203 0.187210772360114 NNMT/KMT2E/KMT2A 3 GO:0055022 negative regulation of cardiac muscle tissue growth 3/504 31/18722 0.0499462392910203 0.187210772360114 MEIS1/CITED2/PTEN 3 GO:0060045 positive regulation of cardiac muscle cell proliferation 3/504 31/18722 0.0499462392910203 0.187210772360114 TBX2/WNT2/MEF2C 3 GO:0060055 angiogenesis involved in wound healing 3/504 31/18722 0.0499462392910203 0.187210772360114 MCAM/ETS1/XBP1 3 GO:0061117 negative regulation of heart growth 3/504 31/18722 0.0499462392910203 0.187210772360114 MEIS1/CITED2/PTEN 3 GO:0070633 transepithelial transport 3/504 31/18722 0.0499462392910203 0.187210772360114 EDNRB/ACTB/ACTG1 3 GO:0110150 negative regulation of biomineralization 3/504 31/18722 0.0499462392910203 0.187210772360114 ENPP1/GAS6/ROCK2 3 GO:0001959 regulation of cytokine-mediated signaling pathway 8/504 150/18722 0.0502489495276863 0.188180334208417 PXDN/SLIT3/GAS6/AXL/IL1R1/CAV1/ISG15/STAT2 8 GO:0097237 cellular response to toxic substance 7/504 124/18722 0.050462633490094 0.188810367683364 PXDN/NXN/FBLN5/MGST1/GPX8/GSTM3/SOD3 7 GO:0043405 regulation of MAP kinase activity 9/504 177/18722 0.0505055582171974 0.188810367683364 THBS1/PDGFRB/FGFR1/CAV1/SPRY1/PDGFA/AIDA/ADAM9/AKAP13 9 GO:0035176 social behavior 4/504 52/18722 0.0509913376286027 0.189796154779634 ATXN1/EXT1/PTEN/EIF4EBP2 4 GO:0043277 apoptotic cell clearance 4/504 52/18722 0.0509913376286027 0.189796154779634 THBS1/MFGE8/GAS6/AXL 4 GO:0043392 negative regulation of DNA binding 4/504 52/18722 0.0509913376286027 0.189796154779634 HAND2/TMSB4X/IFI16/JUN 4 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 4/504 52/18722 0.0509913376286027 0.189796154779634 CTHRC1/GPC3/PTK7/DAAM1 4 GO:0072132 mesenchyme morphogenesis 4/504 52/18722 0.0509913376286027 0.189796154779634 ACTA2/ACTG2/TBX2/TGFB2 4 GO:0043627 response to estrogen 5/504 75/18722 0.0515389751988246 0.191500905238763 IGFBP2/PDGFRB/CAV1/CITED2/GSTM3 5 GO:0061333 renal tubule morphogenesis 5/504 75/18722 0.0515389751988246 0.191500905238763 COL4A1/GPC3/MEF2C/PKD2/PBX1 5 GO:0071496 cellular response to external stimulus 14/504 320/18722 0.0520274253538624 0.193147861457041 COL1A1/MYOCD/GAS6/AXL/KANK2/FOXO1/SLC38A2/CNN2/IFI16/MAP1LC3A/JUN/XBP1/ATF3/BMPR2 14 GO:0000212 meiotic spindle organization 2/504 14/18722 0.0531529639158418 0.194121893002045 MYH9/ATRX 2 GO:0001767 establishment of lymphocyte polarity 2/504 14/18722 0.0531529639158418 0.194121893002045 MYH9/GSN 2 GO:0001771 immunological synapse formation 2/504 14/18722 0.0531529639158418 0.194121893002045 CD81/MSN 2 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 2/504 14/18722 0.0531529639158418 0.194121893002045 COL27A1/SERPINH1 2 GO:0010838 positive regulation of keratinocyte proliferation 2/504 14/18722 0.0531529639158418 0.194121893002045 MDK/NOTCH2 2 GO:0030049 muscle filament sliding 2/504 14/18722 0.0531529639158418 0.194121893002045 TPM1/MYL6 2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 2/504 14/18722 0.0531529639158418 0.194121893002045 EMILIN1/EPN2 2 GO:0034616 response to laminar fluid shear stress 2/504 14/18722 0.0531529639158418 0.194121893002045 ETS1/ADAM9 2 GO:0036295 cellular response to increased oxygen levels 2/504 14/18722 0.0531529639158418 0.194121893002045 FOXO1/CAV1 2 GO:0042921 glucocorticoid receptor signaling pathway 2/504 14/18722 0.0531529639158418 0.194121893002045 NR3C1/CLOCK 2 GO:0046325 negative regulation of glucose import 2/504 14/18722 0.0531529639158418 0.194121893002045 ENPP1/PEA15 2 GO:0050872 white fat cell differentiation 2/504 14/18722 0.0531529639158418 0.194121893002045 PDGFRA/CTBP2 2 GO:0070141 response to UV-A 2/504 14/18722 0.0531529639158418 0.194121893002045 TIMP1/MMP2 2 GO:0070986 left/right axis specification 2/504 14/18722 0.0531529639158418 0.194121893002045 CITED2/NOTCH2 2 GO:0071236 cellular response to antibiotic 2/504 14/18722 0.0531529639158418 0.194121893002045 MEF2C/CRIP1 2 GO:0072160 nephron tubule epithelial cell differentiation 2/504 14/18722 0.0531529639158418 0.194121893002045 MEF2C/WWTR1 2 GO:0072176 nephric duct development 2/504 14/18722 0.0531529639158418 0.194121893002045 GPC3/PKD2 2 GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation 2/504 14/18722 0.0531529639158418 0.194121893002045 MYOCD/EFEMP2 2 GO:2001171 positive regulation of ATP biosynthetic process 2/504 14/18722 0.0531529639158418 0.194121893002045 TMSB4X/STAT3 2 GO:0006941 striated muscle contraction 9/504 179/18722 0.0535078216340293 0.195007967146902 GJC1/FLNA/TPM1/SLC8A1/CAV1/GSN/SMAD5/CALM2/NR4A1 9 GO:0021915 neural tube development 8/504 152/18722 0.0535324936726693 0.195007967146902 CTHRC1/DLC1/TGFB2/SOX4/PTK7/PKD2/CITED2/ZFP36L1 8 GO:0098754 detoxification 8/504 152/18722 0.0535324936726693 0.195007967146902 PXDN/NXN/MT1E/FBLN5/MGST1/GPX8/GSTM3/SOD3 8 GO:0031100 animal organ regeneration 5/504 76/18722 0.0540045089878953 0.195065608267254 NNMT/HGF/GAS6/AXL/SULF2 5 GO:0086001 cardiac muscle cell action potential 5/504 76/18722 0.0540045089878953 0.195065608267254 GJC1/FLNA/SLMAP/SLC8A1/CAV1 5 GO:0007566 embryo implantation 4/504 53/18722 0.0540303591460485 0.195065608267254 IGFBP7/TIMP1/MMP2/VMP1 4 GO:0008347 glial cell migration 4/504 53/18722 0.0540303591460485 0.195065608267254 TGFB2/TSPO/LAMB1/ZMIZ1 4 GO:0043113 receptor clustering 4/504 53/18722 0.0540303591460485 0.195065608267254 THY1/FLNA/CD81/GSN 4 GO:0043620 regulation of DNA-templated transcription in response to stress 4/504 53/18722 0.0540303591460485 0.195065608267254 EGR1/CITED2/JUN/ATF3 4 GO:0010039 response to iron ion 3/504 32/18722 0.0540504751201566 0.195065608267254 CYBRD1/B2M/MAP1LC3A 3 GO:0034367 protein-containing complex remodeling 3/504 32/18722 0.0540504751201566 0.195065608267254 PLA2G2A/AGTR1/LIPG 3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 3/504 32/18722 0.0540504751201566 0.195065608267254 MYOCD/NR2F2/PTEN 3 GO:0051497 negative regulation of stress fiber assembly 3/504 32/18722 0.0540504751201566 0.195065608267254 DLC1/TJP1/PIK3R1 3 GO:0060914 heart formation 3/504 32/18722 0.0540504751201566 0.195065608267254 HAND2/MEF2C/EXT1 3 GO:0098869 cellular oxidant detoxification 6/504 101/18722 0.0552295312524246 0.199152562904312 PXDN/NXN/FBLN5/MGST1/GPX8/SOD3 6 GO:0010524 positive regulation of calcium ion transport into cytosol 4/504 54/18722 0.0571654462352072 0.205439824863785 THY1/CAV1/PKD2/CALM2 4 GO:0014888 striated muscle adaptation 4/504 54/18722 0.0571654462352072 0.205439824863785 IGFBP5/FOXO1/ATP2B4/GSN 4 GO:0051703 biological process involved in intraspecies interaction between organisms 4/504 54/18722 0.0571654462352072 0.205439824863785 ATXN1/EXT1/PTEN/EIF4EBP2 4 GO:0070839 metal ion export 4/504 54/18722 0.0571654462352072 0.205439824863785 FXYD1/SLC8A1/ATP2B4/CALM2 4 GO:0001841 neural tube formation 6/504 102/18722 0.0574139264461929 0.206159418239145 CTHRC1/DLC1/TGFB2/SOX4/PTK7/CITED2 6 GO:0050890 cognition 13/504 296/18722 0.0581987747494703 0.20798230047674 GATM/ADCY3/CCND2/ATXN1/MEF2C/ITGB1/MDK/B2M/JUN/NPTN/PJA2/PTEN/EIF4EBP2 13 GO:0002335 mature B cell differentiation 3/504 33/18722 0.0583109749522898 0.20798230047674 LGALS1/NOTCH2/XBP1 3 GO:0033198 response to ATP 3/504 33/18722 0.0583109749522898 0.20798230047674 SLC8A1/HSP90B1/PTEN 3 GO:0036336 dendritic cell migration 3/504 33/18722 0.0583109749522898 0.20798230047674 GAS6/EXT1/EPS8 3 GO:0045648 positive regulation of erythrocyte differentiation 3/504 33/18722 0.0583109749522898 0.20798230047674 ETS1/ISG15/STAT3 3 GO:0046685 response to arsenic-containing substance 3/504 33/18722 0.0583109749522898 0.20798230047674 SLC38A2/ATF3/PTEN 3 GO:0048730 epidermis morphogenesis 3/504 33/18722 0.0583109749522898 0.20798230047674 IGFBP5/TGFB2/EXT1 3 GO:0071295 cellular response to vitamin 3/504 33/18722 0.0583109749522898 0.20798230047674 COL1A1/GAS6/KANK2 3 GO:0050866 negative regulation of cell activation 10/504 210/18722 0.0584640380168041 0.208354323974816 PRKG1/PDGFRA/EMILIN1/LRRC32/AXL/PAG1/TWSG1/MDK/PRKAR1A/PDGFA 10 GO:0051235 maintenance of location 14/504 326/18722 0.0588636008203031 0.209016042260274 THY1/ENPP1/FLNA/SLC8A1/TMSB4X/SYNE1/CAV1/LTBP1/GSN/FBN1/TSPO/PKD2/CALM2/HSP90B1 14 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5/504 78/18722 0.0591375143348177 0.209016042260274 THBS1/CRYAB/HGF/GAS6/NR4A1 5 GO:0032760 positive regulation of tumor necrosis factor production 6/504 103/18722 0.0596494852564457 0.209016042260274 THBS1/SPON2/AKAP12/HSPB1/STAT3/PIK3R1 6 GO:0006022 aminoglycan metabolic process 7/504 129/18722 0.0599477982189273 0.209016042260274 DCN/PDGFRB/HGF/BGN/EXT1/DSEL/UGDH 7 GO:0007498 mesoderm development 7/504 129/18722 0.0599477982189273 0.209016042260274 TWSG1/ITGB1/EXT1/CITED2/ZFP36L1/PRKAR1A/BMPR2 7 GO:0010832 negative regulation of myotube differentiation 2/504 15/18722 0.0602639279346261 0.209016042260274 MYOCD/XBP1 2 GO:0021542 dentate gyrus development 2/504 15/18722 0.0602639279346261 0.209016042260274 MDK/PTEN 2 GO:0030252 growth hormone secretion 2/504 15/18722 0.0602639279346261 0.209016042260274 LTBP4/ITSN1 2 GO:0031958 corticosteroid receptor signaling pathway 2/504 15/18722 0.0602639279346261 0.209016042260274 NR3C1/CLOCK 2 GO:0032486 Rap protein signal transduction 2/504 15/18722 0.0602639279346261 0.209016042260274 RAP2A/TIMP2 2 GO:0032897 negative regulation of viral transcription 2/504 15/18722 0.0602639279346261 0.209016042260274 IFITM3/ZFP36 2 GO:0033275 actin-myosin filament sliding 2/504 15/18722 0.0602639279346261 0.209016042260274 TPM1/MYL6 2 GO:0036376 sodium ion export across plasma membrane 2/504 15/18722 0.0602639279346261 0.209016042260274 FXYD1/SLC8A1 2 GO:0042249 establishment of planar polarity of embryonic epithelium 2/504 15/18722 0.0602639279346261 0.209016042260274 CTHRC1/PTK7 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/504 15/18722 0.0602639279346261 0.209016042260274 TMSB4X/PKD2 2 GO:0044406 adhesion of symbiont to host 2/504 15/18722 0.0602639279346261 0.209016042260274 GAS6/CD81 2 GO:0045217 cell-cell junction maintenance 2/504 15/18722 0.0602639279346261 0.209016042260274 TJP1/FERMT2 2 GO:0045725 positive regulation of glycogen biosynthetic process 2/504 15/18722 0.0602639279346261 0.209016042260274 DYRK2/IGF2 2 GO:0045986 negative regulation of smooth muscle contraction 2/504 15/18722 0.0602639279346261 0.209016042260274 PRKG1/ARHGAP42 2 GO:0046007 negative regulation of activated T cell proliferation 2/504 15/18722 0.0602639279346261 0.209016042260274 LRRC32/PRKAR1A 2 GO:0048484 enteric nervous system development 2/504 15/18722 0.0602639279346261 0.209016042260274 EDNRA/EDNRB 2 GO:0050746 regulation of lipoprotein metabolic process 2/504 15/18722 0.0602639279346261 0.209016042260274 APOD/LIPG 2 GO:0051127 positive regulation of actin nucleation 2/504 15/18722 0.0602639279346261 0.209016042260274 GSN/NCKAP1 2 GO:0051284 positive regulation of sequestering of calcium ion 2/504 15/18722 0.0602639279346261 0.209016042260274 PKD2/CALM2 2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/504 15/18722 0.0602639279346261 0.209016042260274 ZFP36/TNRC6B 2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 2/504 15/18722 0.0602639279346261 0.209016042260274 DYRK2/ATP2B4 2 GO:0072075 metanephric mesenchyme development 2/504 15/18722 0.0602639279346261 0.209016042260274 PDGFRB/PKD2 2 GO:0090594 inflammatory response to wounding 2/504 15/18722 0.0602639279346261 0.209016042260274 TIMP1/MDK 2 GO:0106057 negative regulation of calcineurin-mediated signaling 2/504 15/18722 0.0602639279346261 0.209016042260274 DYRK2/ATP2B4 2 GO:0150011 regulation of neuron projection arborization 2/504 15/18722 0.0602639279346261 0.209016042260274 MYO9A/MACF1 2 GO:1901660 calcium ion export 2/504 15/18722 0.0602639279346261 0.209016042260274 ATP2B4/CALM2 2 GO:1903729 regulation of plasma membrane organization 2/504 15/18722 0.0602639279346261 0.209016042260274 MYH9/GSN 2 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA 2/504 15/18722 0.0602639279346261 0.209016042260274 NCOR2/STAT3 2 GO:0044091 membrane biogenesis 4/504 55/18722 0.0603960412775099 0.209304366892782 CAV1/SPTBN1/CAV2/PTEN 4 GO:2001257 regulation of cation channel activity 9/504 184/18722 0.0615151663530127 0.213009972306664 SLMAP/MEF2C/ITGB1/TMSB4X/CAV1/PKD2/CALM2/AHNAK/STOM 9 GO:0045621 positive regulation of lymphocyte differentiation 6/504 104/18722 0.0619362582607942 0.21412106112328 GAS6/AXL/MDK/SOX4/XBP1/ZMIZ1 6 GO:0048661 positive regulation of smooth muscle cell proliferation 6/504 104/18722 0.0619362582607942 0.21412106112328 IGFBP5/THBS1/PDGFRB/MMP2/ADAMTS1/JUN 6 GO:1901990 regulation of mitotic cell cycle phase transition 13/504 299/18722 0.0619993150653424 0.214165782760071 FHL1/KANK2/CCND2/HSPA2/SOX4/PKD2/ZFP36L1/KMT2E/ADAMTS1/PTEN/PBX1/TAOK1/NBN 13 GO:0044843 cell cycle G1/S phase transition 11/504 241/18722 0.0622689722438582 0.214923520515352 FHL1/KANK2/CCND2/ITGB1/SOX4/ATP2B4/PKD2/EIF4EBP1/KMT2E/ADAMTS1/PTEN 11 GO:0031128 developmental induction 3/504 34/18722 0.0627247650914708 0.215452509032037 WNT2/SPRY1/HIPK2 3 GO:0048854 brain morphogenesis 3/504 34/18722 0.0627247650914708 0.215452509032037 PTEN/AKT3/SOS1 3 GO:0070884 regulation of calcineurin-NFAT signaling cascade 3/504 34/18722 0.0627247650914708 0.215452509032037 LMCD1/DYRK2/ATP2B4 3 GO:0090075 relaxation of muscle 3/504 34/18722 0.0627247650914708 0.215452509032037 PRKG1/SLC8A1/GSN 3 GO:0098751 bone cell development 3/504 34/18722 0.0627247650914708 0.215452509032037 MEIS1/FBN1/NOTCH2 3 GO:1990000 amyloid fibril formation 3/504 34/18722 0.0627247650914708 0.215452509032037 CRYAB/B2M/GSN 3 GO:0051651 maintenance of location in cell 10/504 213/18722 0.0630728511488315 0.216208690860169 THY1/SLC8A1/TMSB4X/SYNE1/CAV1/GSN/TSPO/PKD2/CALM2/HSP90B1 10 GO:0032102 negative regulation of response to external stimulus 17/504 420/18722 0.063096708987276 0.216208690860169 THBS1/WFDC1/SEMA5A/PRKG1/PDGFRA/HGF/TFPI/A2M/MDK/SERPING1/IFI16/HTRA1/ZFP36/PDGFA/ISG15/PTEN/STAT2 17 GO:0050867 positive regulation of cell activation 17/504 420/18722 0.063096708987276 0.216208690860169 THBS1/IGFBP2/PDGFRB/THY1/GAS6/AXL/LGALS1/MEF2C/CD81/MDK/IL6ST/SOX4/CAV1/B2M/IGF2/XBP1/ZMIZ1 17 GO:0030166 proteoglycan biosynthetic process 4/504 56/18722 0.0637214923072408 0.217130730963987 EXT1/DSEL/UGDH/BMPR2 4 GO:0031529 ruffle organization 4/504 56/18722 0.0637214923072408 0.217130730963987 TPM1/EPS8/CAV1/LIMA1 4 GO:0043388 positive regulation of DNA binding 4/504 56/18722 0.0637214923072408 0.217130730963987 HAND2/MYOCD/HIPK2/CALM2 4 GO:0046622 positive regulation of organ growth 4/504 56/18722 0.0637214923072408 0.217130730963987 TBX2/WNT2/MEF2C/IGF2 4 GO:0051653 spindle localization 4/504 56/18722 0.0637214923072408 0.217130730963987 ITGB1/MYH9/SPRY1/MAP4 4 GO:0055078 sodium ion homeostasis 4/504 56/18722 0.0637214923072408 0.217130730963987 AGTR1/SLC8A1/EXT1/EDNRB 4 GO:0090175 regulation of establishment of planar polarity 4/504 56/18722 0.0637214923072408 0.217130730963987 CTHRC1/GPC3/PTK7/DAAM1 4 GO:0040029 regulation of gene expression, epigenetic 6/504 105/18722 0.0642742682843486 0.218839799505196 XIST/PCGF5/IGF2/IFI16/ZMIZ1/EPC1 6 GO:0120193 tight junction organization 5/504 80/18722 0.0645392503111178 0.219567051416725 MTDH/EXT1/TJP1/ROCK2/ACTG1 5 GO:0000082 G1/S transition of mitotic cell cycle 10/504 214/18722 0.0646597597100107 0.21980203121788 FHL1/KANK2/CCND2/ITGB1/SOX4/PKD2/EIF4EBP1/KMT2E/ADAMTS1/PTEN 10 GO:0003002 regionalization 14/504 331/18722 0.0650069871300002 0.220631339163218 HES4/WNT2/NR2F2/GPC3/MEF2C/EXT1/TSHZ1/SPRY1/CITED2/HIPK2/NOTCH2/AIDA/BMPR2/PBX1 14 GO:0019216 regulation of lipid metabolic process 14/504 331/18722 0.0650069871300002 0.220631339163218 IGFBP7/PDGFRB/AGTR1/RARRES2/APOD/PDGFRA/PLPP1/CD81/CAV1/EGR1/TSPO/LPGAT1/PDGFA/ELOVL5 14 GO:0051962 positive regulation of nervous system development 12/504 272/18722 0.0651596092929887 0.220973817864239 MAP1B/SEMA5A/WNT2/METRN/MDK/IL6ST/PLXND1/TSPO/MACF1/NPTN/MAN2A1/BMPR2 12 GO:0051251 positive regulation of lymphocyte activation 15/504 362/18722 0.0662336474056949 0.223831004567668 IGFBP2/THY1/GAS6/AXL/LGALS1/MEF2C/CD81/MDK/IL6ST/SOX4/CAV1/B2M/IGF2/XBP1/ZMIZ1 15 GO:0006898 receptor-mediated endocytosis 11/504 244/18722 0.0667438437960935 0.223831004567668 RAMP1/PDLIM7/HSPG2/HIP1/CD81/ITGB1/CAV1/B2M/CAV2/ITSN1/MKLN1 11 GO:0061756 leukocyte adhesion to vascular endothelial cell 4/504 57/18722 0.0671410565141238 0.223831004567668 ITGB1/MDK/EXT1/ETS1 4 GO:0001893 maternal placenta development 3/504 35/18722 0.0672886938874954 0.223831004567668 NR2F2/CITED2/BMPR2 3 GO:0003298 physiological muscle hypertrophy 3/504 35/18722 0.0672886938874954 0.223831004567668 SORBS2/PDLIM5/AKAP13 3 GO:0003301 physiological cardiac muscle hypertrophy 3/504 35/18722 0.0672886938874954 0.223831004567668 SORBS2/PDLIM5/AKAP13 3 GO:0021955 central nervous system neuron axonogenesis 3/504 35/18722 0.0672886938874954 0.223831004567668 CDH11/NFIB/PTEN 3 GO:0031076 embryonic camera-type eye development 3/504 35/18722 0.0672886938874954 0.223831004567668 TBX2/CITED2/HIPK2 3 GO:0032232 negative regulation of actin filament bundle assembly 3/504 35/18722 0.0672886938874954 0.223831004567668 DLC1/TJP1/PIK3R1 3 GO:0034331 cell junction maintenance 3/504 35/18722 0.0672886938874954 0.223831004567668 TJP1/FERMT2/CTBP2 3 GO:0043243 positive regulation of protein-containing complex disassembly 3/504 35/18722 0.0672886938874954 0.223831004567668 SEMA5A/DSTN/CFL2 3 GO:0061049 cell growth involved in cardiac muscle cell development 3/504 35/18722 0.0672886938874954 0.223831004567668 SORBS2/PDLIM5/AKAP13 3 GO:0098801 regulation of renal system process 3/504 35/18722 0.0672886938874954 0.223831004567668 AGTR1/GAS6/EDNRB 3 GO:0106056 regulation of calcineurin-mediated signaling 3/504 35/18722 0.0672886938874954 0.223831004567668 LMCD1/DYRK2/ATP2B4 3 GO:1905898 positive regulation of response to endoplasmic reticulum stress 3/504 35/18722 0.0672886938874954 0.223831004567668 CAV1/XBP1/PIK3R1 3 GO:0001942 hair follicle development 5/504 81/18722 0.0673405167375809 0.223831004567668 IGFBP5/TGFB2/EXT1/PDGFA/SOS1 5 GO:0048708 astrocyte differentiation 5/504 81/18722 0.0673405167375809 0.223831004567668 LAMC3/VIM/IL6ST/LAMB2/STAT3 5 GO:0002921 negative regulation of humoral immune response 2/504 16/18722 0.0676783659961214 0.223831004567668 A2M/SERPING1 2 GO:0006349 regulation of gene expression by genetic imprinting 2/504 16/18722 0.0676783659961214 0.223831004567668 PCGF5/IGF2 2 GO:0009048 dosage compensation by inactivation of X chromosome 2/504 16/18722 0.0676783659961214 0.223831004567668 XIST/PCGF5 2 GO:0009299 mRNA transcription 2/504 16/18722 0.0676783659961214 0.223831004567668 FLNA/STAT3 2 GO:0017014 protein nitrosylation 2/504 16/18722 0.0676783659961214 0.223831004567668 ATP2B4/NCOA7 2 GO:0018119 peptidyl-cysteine S-nitrosylation 2/504 16/18722 0.0676783659961214 0.223831004567668 ATP2B4/NCOA7 2 GO:0030575 nuclear body organization 2/504 16/18722 0.0676783659961214 0.223831004567668 ETS1/HIPK2 2 GO:0033631 cell-cell adhesion mediated by integrin 2/504 16/18722 0.0676783659961214 0.223831004567668 ITGB1/ADAM9 2 GO:0034374 low-density lipoprotein particle remodeling 2/504 16/18722 0.0676783659961214 0.223831004567668 PLA2G2A/AGTR1 2 GO:0048385 regulation of retinoic acid receptor signaling pathway 2/504 16/18722 0.0676783659961214 0.223831004567668 CTBP2/DHRS3 2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway 2/504 16/18722 0.0676783659961214 0.223831004567668 DCN/ADGRA2 2 GO:1901201 regulation of extracellular matrix assembly 2/504 16/18722 0.0676783659961214 0.223831004567668 ANTXR1/EMILIN1 2 GO:1904683 regulation of metalloendopeptidase activity 2/504 16/18722 0.0676783659961214 0.223831004567668 TIMP3/STAT3 2 GO:2001212 regulation of vasculogenesis 2/504 16/18722 0.0676783659961214 0.223831004567668 RRAS/RIN2 2 GO:2001224 positive regulation of neuron migration 2/504 16/18722 0.0676783659961214 0.223831004567668 FLNA/MDK 2 GO:0009855 determination of bilateral symmetry 7/504 133/18722 0.0682738118518285 0.225451312243325 TBX2/HAND2/MEF2C/PKD2/CITED2/NOTCH2/AIDA 7 GO:0046328 regulation of JNK cascade 7/504 133/18722 0.0682738118518285 0.225451312243325 RAP2A/HIPK2/MAP4K4/ZMYND11/AIDA/PJA2/TAOK1 7 GO:0050767 regulation of neurogenesis 15/504 364/18722 0.0687203334027263 0.226750567281737 THY1/MAP1B/SEMA5A/WNT2/METRN/MDK/IL6ST/B2M/PLXND1/TSPO/MACF1/NPTN/PTEN/MAN2A1/BMPR2 15 GO:0032526 response to retinoic acid 6/504 107/18722 0.0691039530283925 0.227314235019493 COL1A1/IGFBP7/IGFBP2/PDGFRB/WNT2/PTK7 6 GO:0042303 molting cycle 6/504 107/18722 0.0691039530283925 0.227314235019493 IGFBP5/TGFB2/EXT1/CLOCK/PDGFA/SOS1 6 GO:0042633 hair cycle 6/504 107/18722 0.0691039530283925 0.227314235019493 IGFBP5/TGFB2/EXT1/CLOCK/PDGFA/SOS1 6 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 6/504 107/18722 0.0691039530283925 0.227314235019493 THBS1/SPON2/AKAP12/HSPB1/STAT3/PIK3R1 6 GO:0009799 specification of symmetry 7/504 134/18722 0.0704583536386711 0.231521572706312 TBX2/HAND2/MEF2C/PKD2/CITED2/NOTCH2/AIDA 7 GO:0002931 response to ischemia 4/504 58/18722 0.070653903769958 0.231521572706312 CAV1/EGR1/EIF4EBP1/ROCK2 4 GO:0010043 response to zinc ion 4/504 58/18722 0.070653903769958 0.231521572706312 MT1E/CRIP1/TSPO/PTEN 4 GO:0032387 negative regulation of intracellular transport 4/504 58/18722 0.070653903769958 0.231521572706312 CRYAB/MAP1B/APOD/PKIG 4 GO:2000649 regulation of sodium ion transmembrane transporter activity 4/504 58/18722 0.070653903769958 0.231521572706312 FXYD1/SLMAP/ACTN4/STOM 4 GO:0060759 regulation of response to cytokine stimulus 8/504 162/18722 0.0719856329772913 0.235029524310899 PXDN/SLIT3/GAS6/AXL/IL1R1/CAV1/ISG15/STAT2 8 GO:0014741 negative regulation of muscle hypertrophy 3/504 36/18722 0.0719994494086045 0.235029524310899 IGFBP5/FOXO1/ATP2B4 3 GO:0051354 negative regulation of oxidoreductase activity 3/504 36/18722 0.0719994494086045 0.235029524310899 AOC3/ATP2B4/CAV1 3 GO:0070306 lens fiber cell differentiation 3/504 36/18722 0.0719994494086045 0.235029524310899 VIM/MAF/SPRY1 3 GO:0070873 regulation of glycogen metabolic process 3/504 36/18722 0.0719994494086045 0.235029524310899 ENPP1/DYRK2/IGF2 3 GO:0002687 positive regulation of leukocyte migration 7/504 135/18722 0.07268414829299 0.237083485233547 THBS1/THY1/RARRES2/GAS6/MDK/IL1R1/CD99 7 GO:0031397 negative regulation of protein ubiquitination 5/504 83/18722 0.0731426854188462 0.238397173756468 NXN/SOX4/CAV1/TSPO/ISG15 5 GO:0071322 cellular response to carbohydrate stimulus 8/504 163/18722 0.0740195572292398 0.240895116844784 CAMK2N1/GAS6/LGALS1/SOX4/ZFP36L1/MAP4K4/XBP1/RAB11FIP2 8 GO:0032414 positive regulation of ion transmembrane transporter activity 6/504 109/18722 0.0741381744981125 0.240895116844784 HSPA2/TMSB4X/ACTN4/PKD2/CALM2/VMP1 6 GO:0048010 vascular endothelial growth factor receptor signaling pathway 4/504 59/18722 0.0742591201692374 0.240895116844784 EMILIN1/AXL/HSPB1/EPN2 4 GO:2000351 regulation of endothelial cell apoptotic process 4/504 59/18722 0.0742591201692374 0.240895116844784 THBS1/CD248/SEMA5A/GAS6 4 GO:0097529 myeloid leukocyte migration 10/504 220/18722 0.0747180068598926 0.240895116844784 ITGA1/THBS1/RARRES2/EMILIN1/TGFB2/CD81/MDK/EDNRB/IL1R1/CD99 10 GO:0010612 regulation of cardiac muscle adaptation 2/504 17/18722 0.0753748586991521 0.240895116844784 FOXO1/ATP2B4 2 GO:0010715 regulation of extracellular matrix disassembly 2/504 17/18722 0.0753748586991521 0.240895116844784 DDR2/ETS1 2 GO:0010934 macrophage cytokine production 2/504 17/18722 0.0753748586991521 0.240895116844784 SPON2/TGFB2 2 GO:0010935 regulation of macrophage cytokine production 2/504 17/18722 0.0753748586991521 0.240895116844784 SPON2/TGFB2 2 GO:0016264 gap junction assembly 2/504 17/18722 0.0753748586991521 0.240895116844784 GJC1/CAV1 2 GO:0030002 cellular anion homeostasis 2/504 17/18722 0.0753748586991521 0.240895116844784 ENPP1/CKB 2 GO:0034349 glial cell apoptotic process 2/504 17/18722 0.0753748586991521 0.240895116844784 AKAP12/GAS6 2 GO:0036035 osteoclast development 2/504 17/18722 0.0753748586991521 0.240895116844784 FBN1/NOTCH2 2 GO:0043117 positive regulation of vascular permeability 2/504 17/18722 0.0753748586991521 0.240895116844784 PDE3A/TJP1 2 GO:0046855 inositol phosphate dephosphorylation 2/504 17/18722 0.0753748586991521 0.240895116844784 INPP4B/PTEN 2 GO:0055119 relaxation of cardiac muscle 2/504 17/18722 0.0753748586991521 0.240895116844784 SLC8A1/GSN 2 GO:0060033 anatomical structure regression 2/504 17/18722 0.0753748586991521 0.240895116844784 CD248/SMAD5 2 GO:0060977 coronary vasculature morphogenesis 2/504 17/18722 0.0753748586991521 0.240895116844784 PDGFRB/HAND2 2 GO:0061158 3'-UTR-mediated mRNA destabilization 2/504 17/18722 0.0753748586991521 0.240895116844784 ZFP36L1/ZFP36 2 GO:0070293 renal absorption 2/504 17/18722 0.0753748586991521 0.240895116844784 GAS6/GSN 2 GO:0070875 positive regulation of glycogen metabolic process 2/504 17/18722 0.0753748586991521 0.240895116844784 DYRK2/IGF2 2 GO:0090036 regulation of protein kinase C signaling 2/504 17/18722 0.0753748586991521 0.240895116844784 AKAP12/MYADM 2 GO:1901550 regulation of endothelial cell development 2/504 17/18722 0.0753748586991521 0.240895116844784 VCL/ROCK2 2 GO:1903140 regulation of establishment of endothelial barrier 2/504 17/18722 0.0753748586991521 0.240895116844784 VCL/ROCK2 2 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 2/504 17/18722 0.0753748586991521 0.240895116844784 FOXO1/ATP2B4 2 GO:2000811 negative regulation of anoikis 2/504 17/18722 0.0753748586991521 0.240895116844784 ITGB1/CAV1 2 GO:1902105 regulation of leukocyte differentiation 12/504 279/18722 0.0755478268672009 0.241267462035538 GAS6/AXL/MDK/SOX4/FBN1/ZFP36L1/NOTCH2/JUN/XBP1/PIK3R1/ZMIZ1/SOS1 12 GO:0010660 regulation of muscle cell apoptotic process 5/504 84/18722 0.0761429869702753 0.242443355681063 HSPB6/HAND2/MYOCD/MDK/PTEN 5 GO:0022404 molting cycle process 5/504 84/18722 0.0761429869702753 0.242443355681063 IGFBP5/TGFB2/EXT1/PDGFA/SOS1 5 GO:0022405 hair cycle process 5/504 84/18722 0.0761429869702753 0.242443355681063 IGFBP5/TGFB2/EXT1/PDGFA/SOS1 5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 5/504 84/18722 0.0761429869702753 0.242443355681063 FHL1/KANK2/SOX4/PKD2/PTEN 5 GO:0003014 renal system process 6/504 110/18722 0.0767317546452644 0.24271643077047 MCAM/AGTR1/GAS6/SULF2/EDNRB/GSN 6 GO:0002369 T cell cytokine production 3/504 37/18722 0.0768535761367766 0.24271643077047 CD81/IL1R1/B2M 3 GO:0002724 regulation of T cell cytokine production 3/504 37/18722 0.0768535761367766 0.24271643077047 CD81/IL1R1/B2M 3 GO:0032885 regulation of polysaccharide biosynthetic process 3/504 37/18722 0.0768535761367766 0.24271643077047 ENPP1/DYRK2/IGF2 3 GO:0042401 cellular biogenic amine biosynthetic process 3/504 37/18722 0.0768535761367766 0.24271643077047 NNMT/HAND2/TGFB2 3 GO:0045616 regulation of keratinocyte differentiation 3/504 37/18722 0.0768535761367766 0.24271643077047 ZFP36L1/ZFP36/ROCK2 3 GO:0048846 axon extension involved in axon guidance 3/504 37/18722 0.0768535761367766 0.24271643077047 SLIT3/SEMA5A/BMPR2 3 GO:0051294 establishment of spindle orientation 3/504 37/18722 0.0768535761367766 0.24271643077047 ITGB1/SPRY1/MAP4 3 GO:0060416 response to growth hormone 3/504 37/18722 0.0768535761367766 0.24271643077047 IGFBP5/STAT3/PIK3R1 3 GO:0090218 positive regulation of lipid kinase activity 3/504 37/18722 0.0768535761367766 0.24271643077047 PDGFRB/PDGFRA/CD81 3 GO:1902284 neuron projection extension involved in neuron projection guidance 3/504 37/18722 0.0768535761367766 0.24271643077047 SLIT3/SEMA5A/BMPR2 3 GO:0006986 response to unfolded protein 7/504 137/18722 0.0772594330350815 0.243638049711368 THBS1/HSPA2/SERPINH1/HSPB1/XBP1/ATF3/PIK3R1 7 GO:0030879 mammary gland development 7/504 137/18722 0.0772594330350815 0.243638049711368 IGFBP5/TBX2/WNT2/CAV1/NCOR2/XBP1/ARHGAP5 7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 4/504 60/18722 0.0779557115744497 0.24511019540664 MBNL2/MBNL1/DDX17/RBFOX2 4 GO:0006893 Golgi to plasma membrane transport 4/504 60/18722 0.0779557115744497 0.24511019540664 SPTBN1/PREPL/ARL3/MACF1 4 GO:0042306 regulation of protein import into nucleus 4/504 60/18722 0.0779557115744497 0.24511019540664 APOD/FLNA/PKIG/PIK3R1 4 GO:0051851 modulation by host of symbiont process 4/504 60/18722 0.0779557115744497 0.24511019540664 IFI27/CAV2/JUN/STOM 4 GO:0045069 regulation of viral genome replication 5/504 85/18722 0.0792089593564456 0.248684704871486 IFITM2/IFITM3/IFITM1/IFI16/ISG15 5 GO:0098773 skin epidermis development 5/504 85/18722 0.0792089593564456 0.248684704871486 IGFBP5/TGFB2/EXT1/PDGFA/SOS1 5 GO:0007224 smoothened signaling pathway 7/504 138/18722 0.0796088486916124 0.249756689030293 ENPP1/GAS1/GPC3/EXT1/DYRK2/HIPK2/ARL3 7 GO:0034612 response to tumor necrosis factor 11/504 253/18722 0.0813935589691672 0.25509433106261 COL1A1/THBS1/AKAP12/GAS6/EXT1/TMSB4X/LIMS1/ACTN4/ZFP36L1/ZFP36/ADAM9 11 GO:0030705 cytoskeleton-dependent intracellular transport 9/504 195/18722 0.0817026003260081 0.25509433106261 MAP1B/MYO1B/TUBA1A/DST/ACTN4/HSPB1/MYO10/ARL3/ARMCX3 9 GO:0034113 heterotypic cell-cell adhesion 4/504 61/18722 0.0817426071574506 0.25509433106261 THY1/ITGB1/MYADM/PARVA 4 GO:0043954 cellular component maintenance 4/504 61/18722 0.0817426071574506 0.25509433106261 MYOCD/TJP1/FERMT2/CTBP2 4 GO:0009309 amine biosynthetic process 3/504 38/18722 0.0818474907294261 0.25509433106261 NNMT/HAND2/TGFB2 3 GO:0010719 negative regulation of epithelial to mesenchymal transition 3/504 38/18722 0.0818474907294261 0.25509433106261 TGFB2/SPRY1/PTEN 3 GO:0030279 negative regulation of ossification 3/504 38/18722 0.0818474907294261 0.25509433106261 ENPP1/MEF2C/MDK 3 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 3/504 38/18722 0.0818474907294261 0.25509433106261 KANK2/NCOR2/CLOCK 3 GO:0042596 fear response 3/504 38/18722 0.0818474907294261 0.25509433106261 MEF2C/MDK/EXT1 3 GO:0043406 positive regulation of MAP kinase activity 6/504 112/18722 0.0820711588843552 0.255605001394205 THBS1/PDGFRB/FGFR1/PDGFA/ADAM9/AKAP13 6 GO:0022406 membrane docking 5/504 86/18722 0.0823401934586134 0.256256115548911 SYTL2/CAV2/VMP1/MSN/CTBP2 5 GO:0007254 JNK cascade 8/504 167/18722 0.0824999410380064 0.256358207129716 RAP2A/ARHGEF6/HIPK2/MAP4K4/ZMYND11/AIDA/PJA2/TAOK1 8 GO:0003128 heart field specification 2/504 18/18722 0.083332915914621 0.256358207129716 MEF2C/EXT1 2 GO:0006957 complement activation, alternative pathway 2/504 18/18722 0.083332915914621 0.256358207129716 CFH/CFD 2 GO:0007549 dosage compensation 2/504 18/18722 0.083332915914621 0.256358207129716 XIST/PCGF5 2 GO:0032769 negative regulation of monooxygenase activity 2/504 18/18722 0.083332915914621 0.256358207129716 ATP2B4/CAV1 2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production 2/504 18/18722 0.083332915914621 0.256358207129716 CD81/IL1R1 2 GO:0042693 muscle cell fate commitment 2/504 18/18722 0.083332915914621 0.256358207129716 TBX2/MEF2C 2 GO:0046838 phosphorylated carbohydrate dephosphorylation 2/504 18/18722 0.083332915914621 0.256358207129716 INPP4B/PTEN 2 GO:0048643 positive regulation of skeletal muscle tissue development 2/504 18/18722 0.083332915914621 0.256358207129716 MEF2C/IGF2 2 GO:0060391 positive regulation of SMAD protein signal transduction 2/504 18/18722 0.083332915914621 0.256358207129716 RBPMS/BMPR2 2 GO:0060973 cell migration involved in heart development 2/504 18/18722 0.083332915914621 0.256358207129716 PDGFRB/HAND2 2 GO:0071800 podosome assembly 2/504 18/18722 0.083332915914621 0.256358207129716 GSN/MSN 2 GO:0072234 metanephric nephron tubule development 2/504 18/18722 0.083332915914621 0.256358207129716 PKD2/WWTR1 2 GO:0080182 histone H3-K4 trimethylation 2/504 18/18722 0.083332915914621 0.256358207129716 KMT2E/KMT2A 2 GO:0097709 connective tissue replacement 2/504 18/18722 0.083332915914621 0.256358207129716 TIMP1/ROCK2 2 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 2/504 18/18722 0.083332915914621 0.256358207129716 HAND2/BMPR2 2 GO:0071674 mononuclear cell migration 9/504 196/18722 0.083714907945839 0.257264847669351 THBS1/RARRES2/APOD/GAS6/MDK/EXT1/EPS8/MSN/CD99 9 GO:0008037 cell recognition 10/504 225/18722 0.083808253675576 0.257264847669351 SPON2/MFGE8/SEMA5A/VCAN/NEXN/CD81/PALLD/EXT1/MSN/NPTN 10 GO:0050670 regulation of lymphocyte proliferation 10/504 225/18722 0.083808253675576 0.257264847669351 IGFBP2/LRRC32/TWSG1/MEF2C/CD81/IL6ST/IGF2/PRKAR1A/AHR/SOS1 10 GO:0051924 regulation of calcium ion transport 11/504 255/18722 0.084900878416669 0.260431768466925 MYLK/PDGFRB/THY1/SLC8A1/HSPA2/CAV1/TSPO/PKD2/CALM2/VMP1/AHNAK 11 GO:0048562 embryonic organ morphogenesis 12/504 285/18722 0.0852508372237125 0.261317666755325 CTHRC1/TBX2/HAND2/PDGFRA/MEF2C/TSHZ1/PTK7/FBN1/PKD2/CITED2/HIPK2/NOTCH2 12 GO:0032731 positive regulation of interleukin-1 beta production 4/504 62/18722 0.0856186629289893 0.261881565279578 EGR1/IFI16/HSPB1/STAT3 4 GO:0048488 synaptic vesicle endocytosis 4/504 62/18722 0.0856186629289893 0.261881565279578 ACTB/ITSN1/STON1/ACTG1 4 GO:0140238 presynaptic endocytosis 4/504 62/18722 0.0856186629289893 0.261881565279578 ACTB/ITSN1/STON1/ACTG1 4 GO:0071248 cellular response to metal ion 9/504 197/18722 0.0857567904479065 0.262116427456298 MT1E/MEF2C/B2M/TSPO/PKD2/MAP1LC3A/JUN/MEF2A/SLC25A24 9 GO:0030183 B cell differentiation 7/504 141/18722 0.0869033857296414 0.264711427499332 LGALS1/ITGB1/KLF6/ZFP36L1/NOTCH2/XBP1/PIK3R1 7 GO:0002347 response to tumor cell 3/504 39/18722 0.0869774968895536 0.264711427499332 TXNIP/RBMS3/AHR 3 GO:0046621 negative regulation of organ growth 3/504 39/18722 0.0869774968895536 0.264711427499332 MEIS1/CITED2/PTEN 3 GO:0051154 negative regulation of striated muscle cell differentiation 3/504 39/18722 0.0869774968895536 0.264711427499332 MYOCD/SOX6/XBP1 3 GO:0071548 response to dexamethasone 3/504 39/18722 0.0869774968895536 0.264711427499332 FOXO1/NR3C1/FBXO32 3 GO:1901861 regulation of muscle tissue development 3/504 39/18722 0.0869774968895536 0.264711427499332 IGFBP5/MEF2C/IGF2 3 GO:0046660 female sex differentiation 6/504 114/18722 0.0876123270921655 0.266304198852812 SLIT3/PDGFRA/AXL/NR2F2/ARID5B/ADAMTS1 6 GO:0032944 regulation of mononuclear cell proliferation 10/504 227/18722 0.0876254864467713 0.266304198852812 IGFBP2/LRRC32/TWSG1/MEF2C/CD81/IL6ST/IGF2/PRKAR1A/AHR/SOS1 10 GO:0002696 positive regulation of leukocyte activation 16/504 409/18722 0.087898776694257 0.26694489894425 THBS1/IGFBP2/THY1/GAS6/AXL/LGALS1/MEF2C/CD81/MDK/IL6ST/SOX4/CAV1/B2M/IGF2/XBP1/ZMIZ1 16 GO:0001843 neural tube closure 5/504 88/18722 0.0887966030005668 0.269480031691351 CTHRC1/DLC1/TGFB2/PTK7/CITED2 5 GO:0043087 regulation of GTPase activity 14/504 348/18722 0.0890308189036712 0.269999069677351 THY1/CHN1/PRKG1/ARHGAP42/ITGB1/SPRY1/LIMS1/PLXND1/CAV2/FERMT2/MAP4K4/SBF2/MYO9A/RAB11FIP2 14 GO:1904589 regulation of protein import 4/504 63/18722 0.0895826652490891 0.271479949368339 APOD/FLNA/PKIG/PIK3R1 4 GO:0042098 T cell proliferation 9/504 199/18722 0.0899292081921066 0.272336999719966 IGFBP2/LRRC32/TWSG1/CD81/IL6ST/IGF2/PRKAR1A/MSN/SOS1 9 GO:0042593 glucose homeostasis 11/504 258/18722 0.0903343707576097 0.272407499974903 IGFBP5/CAMK2N1/GAS6/LGALS1/FOXO1/SOX4/MAP4K4/XBP1/STAT3/PIK3R1/RAB11FIP2 11 GO:0071675 regulation of mononuclear cell migration 6/504 115/18722 0.0904580174391665 0.272407499974903 THBS1/RARRES2/APOD/GAS6/MDK/MSN 6 GO:0042129 regulation of T cell proliferation 8/504 171/18722 0.0915308274907813 0.272407499974903 IGFBP2/LRRC32/TWSG1/CD81/IL6ST/IGF2/PRKAR1A/SOS1 8 GO:0010738 regulation of protein kinase A signaling 2/504 19/18722 0.0915329424388228 0.272407499974903 AKAP12/PJA2 2 GO:0010744 positive regulation of macrophage derived foam cell differentiation 2/504 19/18722 0.0915329424388228 0.272407499974903 PLA2G2A/AGTR1 2 GO:0010829 negative regulation of glucose transmembrane transport 2/504 19/18722 0.0915329424388228 0.272407499974903 ENPP1/PEA15 2 GO:0030050 vesicle transport along actin filament 2/504 19/18722 0.0915329424388228 0.272407499974903 MYO1B/ACTN4 2 GO:0032011 ARF protein signal transduction 2/504 19/18722 0.0915329424388228 0.272407499974903 PSD3/MAP4K4 2 GO:0032012 regulation of ARF protein signal transduction 2/504 19/18722 0.0915329424388228 0.272407499974903 PSD3/MAP4K4 2 GO:0044320 cellular response to leptin stimulus 2/504 19/18722 0.0915329424388228 0.272407499974903 STAT3/PTEN 2 GO:0044827 modulation by host of viral genome replication 2/504 19/18722 0.0915329424388228 0.272407499974903 IFI27/STOM 2 GO:0045947 negative regulation of translational initiation 2/504 19/18722 0.0915329424388228 0.272407499974903 EIF4EBP1/EIF4EBP2 2 GO:0046782 regulation of viral transcription 2/504 19/18722 0.0915329424388228 0.272407499974903 IFITM3/ZFP36 2 GO:0051571 positive regulation of histone H3-K4 methylation 2/504 19/18722 0.0915329424388228 0.272407499974903 KMT2E/KMT2A 2 GO:0060039 pericardium development 2/504 19/18722 0.0915329424388228 0.272407499974903 HAND2/SOS1 2 GO:0060065 uterus development 2/504 19/18722 0.0915329424388228 0.272407499974903 MYOCD/TGFB2 2 GO:0060216 definitive hemopoiesis 2/504 19/18722 0.0915329424388228 0.272407499974903 MEIS1/RBFOX2 2 GO:0061323 cell proliferation involved in heart morphogenesis 2/504 19/18722 0.0915329424388228 0.272407499974903 HAND2/BMPR2 2 GO:0071545 inositol phosphate catabolic process 2/504 19/18722 0.0915329424388228 0.272407499974903 INPP4B/PTEN 2 GO:0072074 kidney mesenchyme development 2/504 19/18722 0.0915329424388228 0.272407499974903 PDGFRB/PKD2 2 GO:0086014 atrial cardiac muscle cell action potential 2/504 19/18722 0.0915329424388228 0.272407499974903 GJC1/FLNA 2 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 2/504 19/18722 0.0915329424388228 0.272407499974903 GJC1/FLNA 2 GO:0086066 atrial cardiac muscle cell to AV node cell communication 2/504 19/18722 0.0915329424388228 0.272407499974903 GJC1/FLNA 2 GO:2000738 positive regulation of stem cell differentiation 2/504 19/18722 0.0915329424388228 0.272407499974903 TGFB2/SOX6 2 GO:0071356 cellular response to tumor necrosis factor 10/504 229/18722 0.091546260230274 0.272407499974903 COL1A1/THBS1/AKAP12/GAS6/EXT1/TMSB4X/LIMS1/ACTN4/ZFP36L1/ZFP36 10 GO:0034763 negative regulation of transmembrane transport 7/504 143/18722 0.0919706478221631 0.272573072455667 THBS1/ENPP1/CAV1/PKD2/CALM2/PTEN/PEA15 7 GO:0062013 positive regulation of small molecule metabolic process 7/504 143/18722 0.0919706478221631 0.272573072455667 NNMT/TMSB4X/DYRK2/IGF2/LPGAT1/ELOVL5/STAT3 7 GO:0010657 muscle cell apoptotic process 5/504 89/18722 0.0921207560670993 0.272573072455667 HSPB6/HAND2/MYOCD/MDK/PTEN 5 GO:0051781 positive regulation of cell division 5/504 89/18722 0.0921207560670993 0.272573072455667 TGFB2/MDK/IGF2/SVIL/PDGFA 5 GO:0060606 tube closure 5/504 89/18722 0.0921207560670993 0.272573072455667 CTHRC1/DLC1/TGFB2/PTK7/CITED2 5 GO:0033500 carbohydrate homeostasis 11/504 259/18722 0.0921915562936505 0.272573072455667 IGFBP5/CAMK2N1/GAS6/LGALS1/FOXO1/SOX4/MAP4K4/XBP1/STAT3/PIK3R1/RAB11FIP2 11 GO:0009187 cyclic nucleotide metabolic process 3/504 40/18722 0.0922397993847169 0.272573072455667 GUCY1A2/PDE8B/ADCY3 3 GO:0043001 Golgi to plasma membrane protein transport 3/504 40/18722 0.0922397993847169 0.272573072455667 SPTBN1/PREPL/MACF1 3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 3/504 40/18722 0.0922397993847169 0.272573072455667 THY1/PKD2/CALM2 3 GO:1901223 negative regulation of NIK/NF-kappaB signaling 3/504 40/18722 0.0922397993847169 0.272573072455667 UACA/TMSB4X/HDAC7 3 GO:0046530 photoreceptor cell differentiation 4/504 64/18722 0.0936333343115913 0.27630886568607 THY1/ARL3/STAT3/TUG1 4 GO:0048857 neural nucleus development 4/504 64/18722 0.0936333343115913 0.27630886568607 CKB/NFIB/ACTB/CALM2 4 GO:0030901 midbrain development 5/504 90/18722 0.0955081282890944 0.28106489819511 WNT2/CKB/ACTB/CALM2/SOS1 5 GO:0034644 cellular response to UV 5/504 90/18722 0.0955081282890944 0.28106489819511 TIMP1/MMP2/CRIP1/POLK/PIK3R1 5 GO:0045638 negative regulation of myeloid cell differentiation 5/504 90/18722 0.0955081282890944 0.28106489819511 MEIS1/FBN1/ZFP36L1/ZFP36/PIK3R1 5 GO:0097581 lamellipodium organization 5/504 90/18722 0.0955081282890944 0.28106489819511 VCL/ITGB1/ARHGEF6/NCKAP1/PIK3R1 5 GO:0000910 cytokinesis 8/504 173/18722 0.0962516530330579 0.28305802712337 MYH9/SPTBN1/MAP9/CALM2/SVIL/RHOB/ARL3/ROCK2 8 GO:0010907 positive regulation of glucose metabolic process 3/504 41/18722 0.097630517253567 0.285946842450947 NNMT/DYRK2/IGF2 3 GO:0032733 positive regulation of interleukin-10 production 3/504 41/18722 0.097630517253567 0.285946842450947 HGF/ISG15/STAT3 3 GO:0055023 positive regulation of cardiac muscle tissue growth 3/504 41/18722 0.097630517253567 0.285946842450947 TBX2/WNT2/MEF2C 3 GO:1902622 regulation of neutrophil migration 3/504 41/18722 0.097630517253567 0.285946842450947 MDK/IL1R1/CD99 3 GO:0002720 positive regulation of cytokine production involved in immune response 4/504 65/18722 0.0977693275967314 0.285946842450947 SPON2/CD81/IL1R1/B2M 4 GO:0033692 cellular polysaccharide biosynthetic process 4/504 65/18722 0.0977693275967314 0.285946842450947 ENPP1/EXT1/DYRK2/IGF2 4 GO:0048524 positive regulation of viral process 4/504 65/18722 0.0977693275967314 0.285946842450947 AXL/LGALS1/CAV2/STOM 4 GO:0070613 regulation of protein processing 4/504 65/18722 0.0977693275967314 0.285946842450947 THBS1/GAS1/MYH9/GSN 4 GO:0009636 response to toxic substance 11/504 262/18722 0.0979010813992358 0.286136334349476 PXDN/PDGFRB/MAP1B/NXN/MT1E/FBLN5/MGST1/GPX8/GSTM3/AHR/SOD3 11 GO:0001659 temperature homeostasis 8/504 174/18722 0.0986631156601292 0.287773032911763 LAMA4/GATM/ADAMTS5/FOXO1/EDNRB/CAV1/EGR1/STAT3 8 GO:0045619 regulation of lymphocyte differentiation 8/504 174/18722 0.0986631156601292 0.287773032911763 GAS6/AXL/MDK/SOX4/ZFP36L1/XBP1/ZMIZ1/SOS1 8 GO:0048639 positive regulation of developmental growth 8/504 174/18722 0.0986631156601292 0.287773032911763 MAP1B/SEMA5A/TBX2/WNT2/MEF2C/IGF2/MACF1/BMPR2 8 GO:0001657 ureteric bud development 5/504 91/18722 0.0989581129648265 0.288200312538394 GPC3/SPRY1/PKD2/SMAD5/PBX1 5 GO:0007613 memory 6/504 118/18722 0.0992922586274454 0.288200312538394 CCND2/ATXN1/MDK/PJA2/PTEN/EIF4EBP2 6 GO:0009308 amine metabolic process 6/504 118/18722 0.0992922586274454 0.288200312538394 AOC3/NNMT/HAND2/TGFB2/ATP2B4/MAOA 6 GO:0003159 morphogenesis of an endothelium 2/504 20/18722 0.0999562048167328 0.288200312538394 RHOB/STARD13 2 GO:0006525 arginine metabolic process 2/504 20/18722 0.0999562048167328 0.288200312538394 ATP2B4/DDAH2 2 GO:0006700 C21-steroid hormone biosynthetic process 2/504 20/18722 0.0999562048167328 0.288200312538394 EGR1/TSPO 2 GO:0009713 catechol-containing compound biosynthetic process 2/504 20/18722 0.0999562048167328 0.288200312538394 HAND2/TGFB2 2 GO:0010042 response to manganese ion 2/504 20/18722 0.0999562048167328 0.288200312538394 TSPO/ADAM9 2 GO:0010523 negative regulation of calcium ion transport into cytosol 2/504 20/18722 0.0999562048167328 0.288200312538394 PKD2/CALM2 2 GO:0032495 response to muramyl dipeptide 2/504 20/18722 0.0999562048167328 0.288200312538394 VIM/JAG1 2 GO:0042423 catecholamine biosynthetic process 2/504 20/18722 0.0999562048167328 0.288200312538394 HAND2/TGFB2 2 GO:0045844 positive regulation of striated muscle tissue development 2/504 20/18722 0.0999562048167328 0.288200312538394 MEF2C/IGF2 2 GO:0048636 positive regulation of muscle organ development 2/504 20/18722 0.0999562048167328 0.288200312538394 MEF2C/IGF2 2 GO:0051900 regulation of mitochondrial depolarization 2/504 20/18722 0.0999562048167328 0.288200312538394 DCN/TSPO 2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway 2/504 20/18722 0.0999562048167328 0.288200312538394 ISG15/STAT2 2 GO:0061154 endothelial tube morphogenesis 2/504 20/18722 0.0999562048167328 0.288200312538394 RHOB/STARD13 2 GO:0071243 cellular response to arsenic-containing substance 2/504 20/18722 0.0999562048167328 0.288200312538394 SLC38A2/ATF3 2 GO:0008544 epidermis development 13/504 324/18722 0.100114062375236 0.288460814922038 IGFBP5/TGFB2/TXNIP/JAG1/PALLD/EXT1/ZFP36L1/ZFP36/PDGFA/ROCK2/ADAM9/FOSL2/SOS1 13 GO:0019229 regulation of vasoconstriction 4/504 66/18722 0.101989243286154 0.293468038088712 AGTR1/ARHGAP42/CAV1/BMPR2 4 GO:0045600 positive regulation of fat cell differentiation 4/504 66/18722 0.101989243286154 0.293468038088712 RARRES2/ZFP36L1/ZFP36/XBP1 4 GO:0072163 mesonephric epithelium development 5/504 92/18722 0.102470067219029 0.294455008222537 GPC3/SPRY1/PKD2/SMAD5/PBX1 5 GO:0072164 mesonephric tubule development 5/504 92/18722 0.102470067219029 0.294455008222537 GPC3/SPRY1/PKD2/SMAD5/PBX1 5 GO:0032965 regulation of collagen biosynthetic process 3/504 42/18722 0.103145696237127 0.295601314568239 PDGFRB/EMILIN1/VIM 3 GO:0046688 response to copper ion 3/504 42/18722 0.103145696237127 0.295601314568239 MT1E/MAP1LC3A/SOD3 3 GO:0051602 response to electrical stimulus 3/504 42/18722 0.103145696237127 0.295601314568239 AKAP12/NR4A1/PTEN 3 GO:1904037 positive regulation of epithelial cell apoptotic process 3/504 42/18722 0.103145696237127 0.295601314568239 THBS1/CD248/GSN 3 GO:0051607 defense response to virus 11/504 265/18722 0.103817151373153 0.297046774275904 SPON2/IFITM2/IFI27/IFITM3/IFITM1/IFI16/HTRA1/DDX17/ZMYND11/ISG15/STAT2 11 GO:0140546 defense response to symbiont 11/504 265/18722 0.103817151373153 0.297046774275904 SPON2/IFITM2/IFI27/IFITM3/IFITM1/IFI16/HTRA1/DDX17/ZMYND11/ISG15/STAT2 11 GO:0045930 negative regulation of mitotic cell cycle 10/504 235/18722 0.103928136565054 0.297046774275904 FHL1/KANK2/GAS1/SOX4/TIMP2/PKD2/ZFP36L1/PTEN/TAOK1/NBN 10 GO:2000116 regulation of cysteine-type endopeptidase activity 10/504 235/18722 0.103928136565054 0.297046774275904 THBS1/CRYAB/HGF/GAS6/DLC1/UACA/HIP1/GSN/IFI16/NR4A1 10 GO:0051258 protein polymerization 12/504 296/18722 0.10497233535888 0.29983074130247 MAP1B/LMOD1/ELN/MYADM/TMSB4X/EPS8/SPTBN1/GSN/CDC42EP3/NCKAP1/SVIL/ARL3 12 GO:0035148 tube formation 7/504 148/18722 0.105345150123064 0.300293413259407 CTHRC1/DLC1/TGFB2/NFIB/SOX4/PTK7/CITED2 7 GO:0043484 regulation of RNA splicing 7/504 148/18722 0.105345150123064 0.300293413259407 SLC38A2/MBNL2/MBNL1/AHNAK/DDX17/PIK3R1/RBFOX2 7 GO:0097530 granulocyte migration 7/504 148/18722 0.105345150123064 0.300293413259407 ITGA1/THBS1/RARRES2/TGFB2/MDK/IL1R1/CD99 7 GO:1901019 regulation of calcium ion transmembrane transporter activity 5/504 93/18722 0.106043313155222 0.301440687405733 HSPA2/PKD2/CALM2/VMP1/AHNAK 5 GO:1901992 positive regulation of mitotic cell cycle phase transition 5/504 93/18722 0.106043313155222 0.301440687405733 CCND2/HSPA2/KMT2E/ADAMTS1/PBX1 5 GO:1902807 negative regulation of cell cycle G1/S phase transition 5/504 93/18722 0.106043313155222 0.301440687405733 FHL1/KANK2/SOX4/PKD2/PTEN 5 GO:0090068 positive regulation of cell cycle process 10/504 236/18722 0.106081727391654 0.301440687405733 PDGFRB/CCND2/HSPA2/IGF2/SVIL/KMT2E/ADAMTS1/ROCK2/ATRX/PBX1 10 GO:0051302 regulation of cell division 8/504 177/18722 0.106100349604077 0.301440687405733 TGFB2/TXNIP/MDK/IGF2/MAP9/CALM2/SVIL/PDGFA 8 GO:0061077 chaperone-mediated protein folding 4/504 67/18722 0.106291623635276 0.301783460327929 HSPB6/HSPA2/HSPB1/CRTAP 4 GO:1901987 regulation of cell cycle phase transition 15/504 390/18722 0.106745565476437 0.302871049987263 FHL1/KANK2/CCND2/HSPA2/SOX4/ATP2B4/PKD2/ZFP36L1/KMT2E/ADAMTS1/CLOCK/PTEN/PBX1/TAOK1/NBN 15 GO:0001838 embryonic epithelial tube formation 6/504 121/18722 0.108565442133646 0.303607173331423 CTHRC1/DLC1/TGFB2/SOX4/PTK7/CITED2 6 GO:0000002 mitochondrial genome maintenance 2/504 21/18722 0.108584799297366 0.303607173331423 MEF2A/AKT3 2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 2/504 21/18722 0.108584799297366 0.303607173331423 COX4I2/COX7A1 2 GO:0019985 translesion synthesis 2/504 21/18722 0.108584799297366 0.303607173331423 REV3L/POLK 2 GO:0033630 positive regulation of cell adhesion mediated by integrin 2/504 21/18722 0.108584799297366 0.303607173331423 TGFB2/ADAM9 2 GO:0034035 purine ribonucleoside bisphosphate metabolic process 2/504 21/18722 0.108584799297366 0.303607173331423 ENPP1/PAPSS2 2 GO:0035813 regulation of renal sodium excretion 2/504 21/18722 0.108584799297366 0.303607173331423 AGTR1/EDNRB 2 GO:0045655 regulation of monocyte differentiation 2/504 21/18722 0.108584799297366 0.303607173331423 ZFP36L1/JUN 2 GO:0046823 negative regulation of nucleocytoplasmic transport 2/504 21/18722 0.108584799297366 0.303607173331423 APOD/PKIG 2 GO:0048485 sympathetic nervous system development 2/504 21/18722 0.108584799297366 0.303607173331423 HAND2/SOX4 2 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 2/504 21/18722 0.108584799297366 0.303607173331423 ENPP1/PAPSS2 2 GO:0050849 negative regulation of calcium-mediated signaling 2/504 21/18722 0.108584799297366 0.303607173331423 DYRK2/ATP2B4 2 GO:0051152 positive regulation of smooth muscle cell differentiation 2/504 21/18722 0.108584799297366 0.303607173331423 MYOCD/EFEMP2 2 GO:0060972 left/right pattern formation 2/504 21/18722 0.108584799297366 0.303607173331423 CITED2/NOTCH2 2 GO:0071498 cellular response to fluid shear stress 2/504 21/18722 0.108584799297366 0.303607173331423 MEF2C/PKD2 2 GO:0072170 metanephric tubule development 2/504 21/18722 0.108584799297366 0.303607173331423 PKD2/WWTR1 2 GO:0099515 actin filament-based transport 2/504 21/18722 0.108584799297366 0.303607173331423 MYO1B/ACTN4 2 GO:0150146 cell junction disassembly 2/504 21/18722 0.108584799297366 0.303607173331423 MAP4K4/PIK3R1 2 GO:1901863 positive regulation of muscle tissue development 2/504 21/18722 0.108584799297366 0.303607173331423 MEF2C/IGF2 2 GO:1902307 positive regulation of sodium ion transmembrane transport 2/504 21/18722 0.108584799297366 0.303607173331423 FXYD1/ACTN4 2 GO:0014002 astrocyte development 3/504 43/18722 0.108781320470491 0.303607173331423 LAMC3/VIM/LAMB2 3 GO:0033173 calcineurin-NFAT signaling cascade 3/504 43/18722 0.108781320470491 0.303607173331423 LMCD1/DYRK2/ATP2B4 3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3/504 43/18722 0.108781320470491 0.303607173331423 DYRK2/HIPK2/IFI16 3 GO:0045776 negative regulation of blood pressure 3/504 43/18722 0.108781320470491 0.303607173331423 ARHGAP42/KCNK6/BMPR2 3 GO:0060443 mammary gland morphogenesis 3/504 43/18722 0.108781320470491 0.303607173331423 IGFBP5/TBX2/CAV1 3 GO:0010389 regulation of G2/M transition of mitotic cell cycle 5/504 94/18722 0.109677139019665 0.305708033288341 FHL1/HSPA2/PBX1/TAOK1/NBN 5 GO:0014020 primary neural tube formation 5/504 94/18722 0.109677139019665 0.305708033288341 CTHRC1/DLC1/TGFB2/PTK7/CITED2 5 GO:0007585 respiratory gaseous exchange by respiratory system 4/504 68/18722 0.110674958298374 0.307886781776662 ELN/EDNRA/GLS/MAN2A1 4 GO:0046686 response to cadmium ion 4/504 68/18722 0.110674958298374 0.307886781776662 SPARC/MT1E/B2M/JUN 4 GO:1901016 regulation of potassium ion transmembrane transporter activity 4/504 68/18722 0.110674958298374 0.307886781776662 FHL1/ITGB1/CAV1/PTEN 4 GO:0048638 regulation of developmental growth 13/504 330/18722 0.111003018264344 0.308598501654873 MAP1B/SEMA5A/TBX2/WNT2/MEIS1/MEF2C/IGF2/CITED2/DPYSL2/STAT3/MACF1/PTEN/BMPR2 13 GO:1901991 negative regulation of mitotic cell cycle phase transition 8/504 179/18722 0.111226194230562 0.309017898535235 FHL1/KANK2/SOX4/PKD2/ZFP36L1/PTEN/TAOK1/NBN 8 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 9/504 209/18722 0.112551997849678 0.312498172067364 THBS1/CRYAB/HGF/GAS6/DLC1/UACA/HIP1/GSN/NR4A1 9 GO:0072593 reactive oxygen species metabolic process 10/504 239/18722 0.112695534113267 0.312693517705188 THBS1/PXDN/PDGFRB/CRYAB/AGTR1/FBLN5/SH3PXD2A/TSPO/STAT3/SOD3 10 GO:0008585 female gonad development 5/504 95/18722 0.113370800374775 0.313752221503506 SLIT3/PDGFRA/NR2F2/ARID5B/ADAMTS1 5 GO:0030516 regulation of axon extension 5/504 95/18722 0.113370800374775 0.313752221503506 MAP1B/SEMA5A/DPYSL2/MACF1/BMPR2 5 GO:1901379 regulation of potassium ion transmembrane transport 5/504 95/18722 0.113370800374775 0.313752221503506 FHL1/FLNA/ITGB1/CAV1/PTEN 5 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 5/504 95/18722 0.113370800374775 0.313752221503506 NXN/SOX4/CAV1/TSPO/ISG15 5 GO:0010721 negative regulation of cell development 8/504 180/18722 0.113838960961942 0.314457234153265 THY1/SEMA5A/EDNRB/B2M/ACTN4/FBN1/TSPO/PTEN 8 GO:0030902 hindbrain development 7/504 151/18722 0.113846323715212 0.314457234153265 FLNA/DLC1/CKB/ITGB1/MDK/NFIB/RBFOX2 7 GO:0071333 cellular response to glucose stimulus 7/504 151/18722 0.113846323715212 0.314457234153265 CAMK2N1/GAS6/LGALS1/SOX4/MAP4K4/XBP1/RAB11FIP2 7 GO:0051098 regulation of binding 14/504 363/18722 0.114341378228376 0.314929788406544 CTHRC1/HAND2/MYOCD/RAMP1/TMSB4X/ACTB/CAV1/B2M/PLXND1/HIPK2/CALM2/IFI16/JUN/CTBP2 14 GO:0005978 glycogen biosynthetic process 3/504 44/18722 0.114533323469171 0.314929788406544 ENPP1/DYRK2/IGF2 3 GO:0009250 glucan biosynthetic process 3/504 44/18722 0.114533323469171 0.314929788406544 ENPP1/DYRK2/IGF2 3 GO:0021762 substantia nigra development 3/504 44/18722 0.114533323469171 0.314929788406544 CKB/ACTB/CALM2 3 GO:0031295 T cell costimulation 3/504 44/18722 0.114533323469171 0.314929788406544 LGALS1/CD81/CAV1 3 GO:0032881 regulation of polysaccharide metabolic process 3/504 44/18722 0.114533323469171 0.314929788406544 ENPP1/DYRK2/IGF2 3 GO:0050999 regulation of nitric-oxide synthase activity 3/504 44/18722 0.114533323469171 0.314929788406544 ATP2B4/CAV1/DDAH2 3 GO:0006913 nucleocytoplasmic transport 12/504 301/18722 0.114761808918965 0.315152448271682 APOD/FLNA/GAS6/TXNIP/IFI27/ATXN1/PKIG/STAT3/PIK3R1/PPP1R12A/AKAP13/KPNA3 12 GO:0051169 nuclear transport 12/504 301/18722 0.114761808918965 0.315152448271682 APOD/FLNA/GAS6/TXNIP/IFI27/ATXN1/PKIG/STAT3/PIK3R1/PPP1R12A/AKAP13/KPNA3 12 GO:0007623 circadian rhythm 9/504 210/18722 0.114973846797419 0.315531950780584 ID4/EGR1/ZFHX3/CLOCK/JUN/ROCK2/PTEN/KMT2A/AHR 9 GO:0031060 regulation of histone methylation 4/504 69/18722 0.115137687602235 0.315576227789833 NNMT/KMT2E/ATRX/KMT2A 4 GO:0045665 negative regulation of neuron differentiation 4/504 69/18722 0.115137687602235 0.315576227789833 MEIS1/JAG1/B2M/PBX1 4 GO:0008361 regulation of cell size 8/504 181/18722 0.116484726868248 0.317504510151519 MAP1B/SEMA5A/DPYSL2/MSN/MACF1/PTEN/BMPR2/AKT3 8 GO:0008643 carbohydrate transport 7/504 152/18722 0.116758025855197 0.317504510151519 EDNRA/ENPP1/GPC3/RHOQ/MEF2A/PIK3R1/PEA15 7 GO:0001823 mesonephros development 5/504 96/18722 0.117123521279922 0.317504510151519 GPC3/SPRY1/PKD2/SMAD5/PBX1 5 GO:0002718 regulation of cytokine production involved in immune response 5/504 96/18722 0.117123521279922 0.317504510151519 SPON2/TGFB2/CD81/IL1R1/B2M 5 GO:0044264 cellular polysaccharide metabolic process 5/504 96/18722 0.117123521279922 0.317504510151519 ENPP1/EXT1/IL6ST/DYRK2/IGF2 5 GO:0002053 positive regulation of mesenchymal cell proliferation 2/504 22/18722 0.117401620884484 0.317504510151519 WNT2/PDGFA 2 GO:0002320 lymphoid progenitor cell differentiation 2/504 22/18722 0.117401620884484 0.317504510151519 SOX4/SOS1 2 GO:0006907 pinocytosis 2/504 22/18722 0.117401620884484 0.317504510151519 AXL/CAV1 2 GO:0009190 cyclic nucleotide biosynthetic process 2/504 22/18722 0.117401620884484 0.317504510151519 GUCY1A2/ADCY3 2 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 2/504 22/18722 0.117401620884484 0.317504510151519 SLC8A1/CALM2 2 GO:0014821 phasic smooth muscle contraction 2/504 22/18722 0.117401620884484 0.317504510151519 TBX2/EDNRB 2 GO:0032816 positive regulation of natural killer cell activation 2/504 22/18722 0.117401620884484 0.317504510151519 GAS6/AXL 2 GO:0035357 peroxisome proliferator activated receptor signaling pathway 2/504 22/18722 0.117401620884484 0.317504510151519 ACTN4/CITED2 2 GO:0045663 positive regulation of myoblast differentiation 2/504 22/18722 0.117401620884484 0.317504510151519 IGFBP3/MEF2C 2 GO:0046058 cAMP metabolic process 2/504 22/18722 0.117401620884484 0.317504510151519 PDE8B/ADCY3 2 GO:0052652 cyclic purine nucleotide metabolic process 2/504 22/18722 0.117401620884484 0.317504510151519 GUCY1A2/ADCY3 2 GO:0061042 vascular wound healing 2/504 22/18722 0.117401620884484 0.317504510151519 MCAM/XBP1 2 GO:0071404 cellular response to low-density lipoprotein particle stimulus 2/504 22/18722 0.117401620884484 0.317504510151519 CD81/ITGB1 2 GO:0086012 membrane depolarization during cardiac muscle cell action potential 2/504 22/18722 0.117401620884484 0.317504510151519 SLMAP/SLC8A1 2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 2/504 22/18722 0.117401620884484 0.317504510151519 SMAD5/XBP1 2 GO:2000114 regulation of establishment of cell polarity 2/504 22/18722 0.117401620884484 0.317504510151519 GSN/ROCK2 2 GO:0007368 determination of left/right symmetry 6/504 124/18722 0.118267286776554 0.31964333737901 TBX2/HAND2/MEF2C/PKD2/CITED2/NOTCH2 6 GO:0062012 regulation of small molecule metabolic process 13/504 334/18722 0.118636103533522 0.320437465485929 IGFBP4/NNMT/ENPP1/TMSB4X/DYRK2/ATP2B4/CAV1/EGR1/IGF2/LPGAT1/NCOR2/ELOVL5/STAT3 13 GO:0003407 neural retina development 4/504 70/18722 0.119678205764604 0.322925114620083 THY1/TGFB2/ATP2B4/HIPK2 4 GO:0071331 cellular response to hexose stimulus 7/504 153/18722 0.119708256858931 0.322925114620083 CAMK2N1/GAS6/LGALS1/SOX4/MAP4K4/XBP1/RAB11FIP2 7 GO:0006457 protein folding 9/504 212/18722 0.119903187128427 0.323246888706479 CRYAB/HSPB6/LTBP4/HSPA2/B2M/QSOX1/HSPB1/CRTAP/HSP90B1 9 GO:0002920 regulation of humoral immune response 3/504 45/18722 0.120397598442922 0.323355712222883 CFH/A2M/SERPING1 3 GO:0046189 phenol-containing compound biosynthetic process 3/504 45/18722 0.120397598442922 0.323355712222883 HAND2/TGFB2/ZEB2 3 GO:0048538 thymus development 3/504 45/18722 0.120397598442922 0.323355712222883 HAND2/CITED2/PBX1 3 GO:0060421 positive regulation of heart growth 3/504 45/18722 0.120397598442922 0.323355712222883 TBX2/WNT2/MEF2C 3 GO:0071354 cellular response to interleukin-6 3/504 45/18722 0.120397598442922 0.323355712222883 IL6ST/JAK1/STAT3 3 GO:0071364 cellular response to epidermal growth factor stimulus 3/504 45/18722 0.120397598442922 0.323355712222883 COL1A1/ZFP36L1/ZFP36 3 GO:0009615 response to virus 14/504 367/18722 0.121743067550139 0.326763899272454 ACTA2/SPON2/IFITM2/IFI27/IFITM3/IFITM1/EXT1/IFI16/HSPB1/HTRA1/DDX17/ZMYND11/ISG15/STAT2 14 GO:0071326 cellular response to monosaccharide stimulus 7/504 154/18722 0.122696719426754 0.329116812373208 CAMK2N1/GAS6/LGALS1/SOX4/MAP4K4/XBP1/RAB11FIP2 7 GO:0043550 regulation of lipid kinase activity 4/504 71/18722 0.124294864054085 0.331939701794335 PDGFRB/PDGFRA/CD81/PIK3R1 4 GO:0050795 regulation of behavior 4/504 71/18722 0.124294864054085 0.331939701794335 MEF2C/MDK/ZFHX3/STAT3 4 GO:0061515 myeloid cell development 4/504 71/18722 0.124294864054085 0.331939701794335 MEIS1/FBN1/CITED2/NOTCH2 4 GO:0002367 cytokine production involved in immune response 5/504 98/18722 0.124802887583157 0.331939701794335 SPON2/TGFB2/CD81/IL1R1/B2M 5 GO:2001235 positive regulation of apoptotic signaling pathway 6/504 126/18722 0.124967467246324 0.331939701794335 THBS1/CAV1/TIMP3/ATF3/PTEN/PEA15 6 GO:0006606 protein import into nucleus 7/504 155/18722 0.1257231023959 0.331939701794335 APOD/FLNA/TXNIP/PKIG/STAT3/PIK3R1/KPNA3 7 GO:0051147 regulation of muscle cell differentiation 7/504 155/18722 0.1257231023959 0.331939701794335 MYOCD/EFEMP2/MEF2C/SOX6/IGF2/XBP1/BMPR2 7 GO:0031294 lymphocyte costimulation 3/504 46/18722 0.126370007968543 0.331939701794335 LGALS1/CD81/CAV1 3 GO:0034198 cellular response to amino acid starvation 3/504 46/18722 0.126370007968543 0.331939701794335 SLC38A2/MAP1LC3A/ATF3 3 GO:0042398 cellular modified amino acid biosynthetic process 3/504 46/18722 0.126370007968543 0.331939701794335 GATM/CKB/PLOD2 3 GO:0043462 regulation of ATPase activity 3/504 46/18722 0.126370007968543 0.331939701794335 TPM2/TPM1/CNN3 3 GO:0046839 phospholipid dephosphorylation 3/504 46/18722 0.126370007968543 0.331939701794335 PLPP1/INPP4B/PTEN 3 GO:0050919 negative chemotaxis 3/504 46/18722 0.126370007968543 0.331939701794335 SLIT3/SEMA5A/PDGFA 3 GO:0071827 plasma lipoprotein particle organization 3/504 46/18722 0.126370007968543 0.331939701794335 PLA2G2A/AGTR1/LIPG 3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 3/504 46/18722 0.126370007968543 0.331939701794335 CCND2/KMT2E/ADAMTS1 3 GO:0001759 organ induction 2/504 23/18722 0.126390333447082 0.331939701794335 WNT2/SPRY1 2 GO:0019430 removal of superoxide radicals 2/504 23/18722 0.126390333447082 0.331939701794335 FBLN5/SOD3 2 GO:0035162 embryonic hemopoiesis 2/504 23/18722 0.126390333447082 0.331939701794335 PBX1/KMT2A 2 GO:0035812 renal sodium excretion 2/504 23/18722 0.126390333447082 0.331939701794335 AGTR1/EDNRB 2 GO:0035994 response to muscle stretch 2/504 23/18722 0.126390333447082 0.331939701794335 SLC8A1/GSN 2 GO:0042026 protein refolding 2/504 23/18722 0.126390333447082 0.331939701794335 HSPA2/B2M 2 GO:0045723 positive regulation of fatty acid biosynthetic process 2/504 23/18722 0.126390333447082 0.331939701794335 LPGAT1/ELOVL5 2 GO:0045932 negative regulation of muscle contraction 2/504 23/18722 0.126390333447082 0.331939701794335 PRKG1/ARHGAP42 2 GO:0050765 negative regulation of phagocytosis 2/504 23/18722 0.126390333447082 0.331939701794335 CNN2/PTEN 2 GO:0051882 mitochondrial depolarization 2/504 23/18722 0.126390333447082 0.331939701794335 DCN/TSPO 2 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 2/504 23/18722 0.126390333447082 0.331939701794335 EHD2/ADAM9 2 GO:0060353 regulation of cell adhesion molecule production 2/504 23/18722 0.126390333447082 0.331939701794335 MYOCD/CAV1 2 GO:0060396 growth hormone receptor signaling pathway 2/504 23/18722 0.126390333447082 0.331939701794335 STAT3/PIK3R1 2 GO:0071514 genetic imprinting 2/504 23/18722 0.126390333447082 0.331939701794335 PCGF5/IGF2 2 GO:0071636 positive regulation of transforming growth factor beta production 2/504 23/18722 0.126390333447082 0.331939701794335 LUM/THBS1 2 GO:0090103 cochlea morphogenesis 2/504 23/18722 0.126390333447082 0.331939701794335 CTHRC1/PTK7 2 GO:2000737 negative regulation of stem cell differentiation 2/504 23/18722 0.126390333447082 0.331939701794335 JAG1/STAT3 2 GO:2000810 regulation of bicellular tight junction assembly 2/504 23/18722 0.126390333447082 0.331939701794335 TJP1/ROCK2 2 GO:2001169 regulation of ATP biosynthetic process 2/504 23/18722 0.126390333447082 0.331939701794335 TMSB4X/STAT3 2 GO:0070663 regulation of leukocyte proliferation 10/504 245/18722 0.126604342024401 0.332297514416625 IGFBP2/LRRC32/TWSG1/MEF2C/CD81/IL6ST/IGF2/PRKAR1A/AHR/SOS1 10 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 5/504 99/18722 0.12872783427598 0.33668727332045 CRIP1/DYRK2/HIPK2/IFI16/PIK3R1 5 GO:0033209 tumor necrosis factor-mediated signaling pathway 5/504 99/18722 0.12872783427598 0.33668727332045 GAS6/EXT1/TMSB4X/LIMS1/ACTN4 5 GO:0000271 polysaccharide biosynthetic process 4/504 72/18722 0.128985973888504 0.33668727332045 ENPP1/EXT1/DYRK2/IGF2 4 GO:0001707 mesoderm formation 4/504 72/18722 0.128985973888504 0.33668727332045 TWSG1/ITGB1/PRKAR1A/BMPR2 4 GO:0001736 establishment of planar polarity 4/504 72/18722 0.128985973888504 0.33668727332045 CTHRC1/GPC3/PTK7/DAAM1 4 GO:0005977 glycogen metabolic process 4/504 72/18722 0.128985973888504 0.33668727332045 ENPP1/IL6ST/DYRK2/IGF2 4 GO:0007164 establishment of tissue polarity 4/504 72/18722 0.128985973888504 0.33668727332045 CTHRC1/GPC3/PTK7/DAAM1 4 GO:0030330 DNA damage response, signal transduction by p53 class mediator 4/504 72/18722 0.128985973888504 0.33668727332045 SOX4/HIPK2/ATRX/NBN 4 GO:0035567 non-canonical Wnt signaling pathway 4/504 72/18722 0.128985973888504 0.33668727332045 CTHRC1/GPC3/PTK7/DAAM1 4 GO:0006909 phagocytosis 12/504 308/18722 0.129322277482014 0.337359030330064 THBS1/SPON2/MFGE8/GAS6/AXL/ITGB1/MYH9/CNN2/GSN/CD302/PTEN/RAB11FIP2 12 GO:0120032 regulation of plasma membrane bounded cell projection assembly 8/504 186/18722 0.130201674397053 0.33944585399549 EPS8/CAV1/RHOQ/CDC42EP3/NCKAP1/MYO10/MAP4/PIK3R1 8 GO:2000377 regulation of reactive oxygen species metabolic process 7/504 157/18722 0.131888317174919 0.343633402005139 THBS1/PDGFRB/CRYAB/AGTR1/FBLN5/TSPO/STAT3 7 GO:0001754 eye photoreceptor cell differentiation 3/504 47/18722 0.132446393051847 0.343829548912844 THY1/STAT3/TUG1 3 GO:0007595 lactation 3/504 47/18722 0.132446393051847 0.343829548912844 CAV1/NCOR2/XBP1 3 GO:0048512 circadian behavior 3/504 47/18722 0.132446393051847 0.343829548912844 EGR1/ZFHX3/PTEN 3 GO:0051489 regulation of filopodium assembly 3/504 47/18722 0.132446393051847 0.343829548912844 RHOQ/MYO10/PIK3R1 3 GO:0097028 dendritic cell differentiation 3/504 47/18722 0.132446393051847 0.343829548912844 GAS6/AXL/NOTCH2 3 GO:1900744 regulation of p38MAPK cascade 3/504 47/18722 0.132446393051847 0.343829548912844 HAND2/HGF/PJA2 3 GO:0045807 positive regulation of endocytosis 5/504 100/18722 0.132708445490868 0.343883073124608 AXL/HIP1/GPC3/B2M/ITSN1 5 GO:0046545 development of primary female sexual characteristics 5/504 100/18722 0.132708445490868 0.343883073124608 SLIT3/PDGFRA/NR2F2/ARID5B/ADAMTS1 5 GO:0061640 cytoskeleton-dependent cytokinesis 5/504 100/18722 0.132708445490868 0.343883073124608 SPTBN1/MAP9/RHOB/ARL3/ROCK2 5 GO:0006073 cellular glucan metabolic process 4/504 73/18722 0.133749809869091 0.345533819571116 ENPP1/IL6ST/DYRK2/IGF2 4 GO:0032732 positive regulation of interleukin-1 production 4/504 73/18722 0.133749809869091 0.345533819571116 EGR1/IFI16/HSPB1/STAT3 4 GO:0044042 glucan metabolic process 4/504 73/18722 0.133749809869091 0.345533819571116 ENPP1/IL6ST/DYRK2/IGF2 4 GO:0050848 regulation of calcium-mediated signaling 4/504 73/18722 0.133749809869091 0.345533819571116 LMCD1/DYRK2/ATP2B4/CALM2 4 GO:0086003 cardiac muscle cell contraction 4/504 73/18722 0.133749809869091 0.345533819571116 GJC1/FLNA/CAV1/GSN 4 GO:0010155 regulation of proton transport 2/504 24/18722 0.1355353408552 0.346377100164038 TMSB4X/ACTN4 2 GO:0010288 response to lead ion 2/504 24/18722 0.1355353408552 0.346377100164038 SPARC/MAP1LC3A 2 GO:0021801 cerebral cortex radial glia-guided migration 2/504 24/18722 0.1355353408552 0.346377100164038 LAMB1/ZMIZ1 2 GO:0022030 telencephalon glial cell migration 2/504 24/18722 0.1355353408552 0.346377100164038 LAMB1/ZMIZ1 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/504 24/18722 0.1355353408552 0.346377100164038 TMSB4X/STAT3 2 GO:0033032 regulation of myeloid cell apoptotic process 2/504 24/18722 0.1355353408552 0.346377100164038 MEF2C/PTEN 2 GO:0035458 cellular response to interferon-beta 2/504 24/18722 0.1355353408552 0.346377100164038 IFITM2/IFI16 2 GO:0036010 protein localization to endosome 2/504 24/18722 0.1355353408552 0.346377100164038 ROCK2/MSN 2 GO:0044062 regulation of excretion 2/504 24/18722 0.1355353408552 0.346377100164038 AGTR1/EDNRB 2 GO:0044321 response to leptin 2/504 24/18722 0.1355353408552 0.346377100164038 STAT3/PTEN 2 GO:0048011 neurotrophin TRK receptor signaling pathway 2/504 24/18722 0.1355353408552 0.346377100164038 SPRY1/SOS1 2 GO:0048641 regulation of skeletal muscle tissue development 2/504 24/18722 0.1355353408552 0.346377100164038 MEF2C/IGF2 2 GO:0050855 regulation of B cell receptor signaling pathway 2/504 24/18722 0.1355353408552 0.346377100164038 CD81/CMTM3 2 GO:0071294 cellular response to zinc ion 2/504 24/18722 0.1355353408552 0.346377100164038 MT1E/TSPO 2 GO:0071378 cellular response to growth hormone stimulus 2/504 24/18722 0.1355353408552 0.346377100164038 STAT3/PIK3R1 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/504 24/18722 0.1355353408552 0.346377100164038 TMSB4X/STAT3 2 GO:2000209 regulation of anoikis 2/504 24/18722 0.1355353408552 0.346377100164038 ITGB1/CAV1 2 GO:2000353 positive regulation of endothelial cell apoptotic process 2/504 24/18722 0.1355353408552 0.346377100164038 THBS1/CD248 2 GO:0060491 regulation of cell projection assembly 8/504 188/18722 0.135912153103529 0.34713247472288 EPS8/CAV1/RHOQ/CDC42EP3/NCKAP1/MYO10/MAP4/PIK3R1 8 GO:0035966 response to topologically incorrect protein 7/504 159/18722 0.138201144898232 0.352136846839681 THBS1/HSPA2/SERPINH1/HSPB1/XBP1/ATF3/PIK3R1 7 GO:0046488 phosphatidylinositol metabolic process 7/504 159/18722 0.138201144898232 0.352136846839681 PDGFRB/INPP4B/FAM126A/LPGAT1/PDGFA/PIK3R1/PTEN 7 GO:0051170 import into nucleus 7/504 159/18722 0.138201144898232 0.352136846839681 APOD/FLNA/TXNIP/PKIG/STAT3/PIK3R1/KPNA3 7 GO:1903169 regulation of calcium ion transmembrane transport 7/504 159/18722 0.138201144898232 0.352136846839681 THY1/SLC8A1/HSPA2/PKD2/CALM2/VMP1/AHNAK 7 GO:0048332 mesoderm morphogenesis 4/504 74/18722 0.138584612748183 0.352370191082698 TWSG1/ITGB1/PRKAR1A/BMPR2 4 GO:0120192 tight junction assembly 4/504 74/18722 0.138584612748183 0.352370191082698 MTDH/TJP1/ROCK2/ACTG1 4 GO:0002673 regulation of acute inflammatory response 3/504 48/18722 0.138622581607773 0.352370191082698 OSMR/EDNRB/IL6ST 3 GO:0097720 calcineurin-mediated signaling 3/504 48/18722 0.138622581607773 0.352370191082698 LMCD1/DYRK2/ATP2B4 3 GO:0006956 complement activation 6/504 130/18722 0.138907342225192 0.352748605803186 C1R/CFH/C1S/A2M/SERPING1/CFD 6 GO:0051090 regulation of DNA-binding transcription factor activity 16/504 440/18722 0.138936555948224 0.352748605803186 DDR2/HAND2/MYOCD/WNT2/ENPP1/FLNA/GAS6/MTDH/TMSB4X/CAV1/PKD2/HIPK2/ARID5B/CLOCK/STAT3/PTEN 16 GO:0018205 peptidyl-lysine modification 14/504 376/18722 0.139385178324305 0.353677474453537 NNMT/MYOCD/FKBP10/SOX4/EGR1/P3H4/HDAC7/KMT2E/CLOCK/ATRX/PLOD2/ZMIZ1/KMT2A/EPC1 14 GO:0010522 regulation of calcium ion transport into cytosol 5/504 102/18722 0.140832974636384 0.356927224567775 THY1/SLC8A1/CAV1/PKD2/CALM2 5 GO:1902749 regulation of cell cycle G2/M phase transition 5/504 102/18722 0.140832974636384 0.356927224567775 FHL1/HSPA2/PBX1/TAOK1/NBN 5 GO:0035637 multicellular organismal signaling 7/504 160/18722 0.141411996192109 0.358182252358554 GJC1/FLNA/SLC8A1/ATP2B4/CAV1/CALM2/MEF2A 7 GO:0009755 hormone-mediated signaling pathway 8/504 190/18722 0.141747538048873 0.358819449101205 PLPP1/KANK2/NR3C1/NCOR2/DDX17/CLOCK/RBFOX2/ZMIZ1 8 GO:0006024 glycosaminoglycan biosynthetic process 4/504 75/18722 0.143488592328428 0.361432431849991 PDGFRB/EXT1/DSEL/UGDH 4 GO:0036465 synaptic vesicle recycling 4/504 75/18722 0.143488592328428 0.361432431849991 ACTB/ITSN1/STON1/ACTG1 4 GO:0051960 regulation of nervous system development 16/504 443/18722 0.144617769982863 0.361432431849991 THY1/MAP1B/SEMA5A/WNT2/HGF/METRN/MDK/IL6ST/B2M/PLXND1/TSPO/MACF1/NPTN/PTEN/MAN2A1/BMPR2 16 GO:0050821 protein stabilization 8/504 191/18722 0.14471140254899 0.361432431849991 CRYAB/FLNA/HIP1/SOX4/CRTAP/PARVA/PIK3R1/PTEN 8 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 2/504 25/18722 0.144821759107687 0.361432431849991 AGTR1/GAS6 2 GO:0010954 positive regulation of protein processing 2/504 25/18722 0.144821759107687 0.361432431849991 MYH9/GSN 2 GO:0015012 heparan sulfate proteoglycan biosynthetic process 2/504 25/18722 0.144821759107687 0.361432431849991 EXT1/UGDH 2 GO:0032878 regulation of establishment or maintenance of cell polarity 2/504 25/18722 0.144821759107687 0.361432431849991 GSN/ROCK2 2 GO:0033233 regulation of protein sumoylation 2/504 25/18722 0.144821759107687 0.361432431849991 EGR1/ZMIZ1 2 GO:0033622 integrin activation 2/504 25/18722 0.144821759107687 0.361432431849991 FERMT2/TLN1 2 GO:0042730 fibrinolysis 2/504 25/18722 0.144821759107687 0.361432431849991 THBS1/SERPING1 2 GO:0051291 protein heterooligomerization 2/504 25/18722 0.144821759107687 0.361432431849991 COL1A2/PKD2 2 GO:0051450 myoblast proliferation 2/504 25/18722 0.144821759107687 0.361432431849991 HGF/MALAT1 2 GO:0060074 synapse maturation 2/504 25/18722 0.144821759107687 0.361432431849991 NFIA/PTEN 2 GO:0071450 cellular response to oxygen radical 2/504 25/18722 0.144821759107687 0.361432431849991 FBLN5/SOD3 2 GO:0071451 cellular response to superoxide 2/504 25/18722 0.144821759107687 0.361432431849991 FBLN5/SOD3 2 GO:0072202 cell differentiation involved in metanephros development 2/504 25/18722 0.144821759107687 0.361432431849991 LAMB2/WWTR1 2 GO:0090330 regulation of platelet aggregation 2/504 25/18722 0.144821759107687 0.361432431849991 PRKG1/IL6ST 2 GO:0098703 calcium ion import across plasma membrane 2/504 25/18722 0.144821759107687 0.361432431849991 SLC8A1/ATP2B4 2 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 2/504 25/18722 0.144821759107687 0.361432431849991 IGFBP5/ADAMTS1 2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 2/504 25/18722 0.144821759107687 0.361432431849991 MDK/ETS1 2 GO:0007622 rhythmic behavior 3/504 49/18722 0.144894396386388 0.361432431849991 EGR1/ZFHX3/PTEN 3 GO:0042461 photoreceptor cell development 3/504 49/18722 0.144894396386388 0.361432431849991 THY1/ARL3/TUG1 3 GO:0070741 response to interleukin-6 3/504 49/18722 0.144894396386388 0.361432431849991 IL6ST/JAK1/STAT3 3 GO:0070849 response to epidermal growth factor 3/504 49/18722 0.144894396386388 0.361432431849991 COL1A1/ZFP36L1/ZFP36 3 GO:0072175 epithelial tube formation 6/504 132/18722 0.146138244077024 0.364322471960983 CTHRC1/DLC1/TGFB2/SOX4/PTK7/CITED2 6 GO:0097305 response to alcohol 10/504 253/18722 0.146527292068855 0.365079369685258 IGFBP7/SPARC/SLIT3/ADCY3/EPS8/TSPO/EIF4EBP1/STAT3/PTEN/AHR 10 GO:0051100 negative regulation of binding 7/504 162/18722 0.147940631198946 0.368385965683622 HAND2/TMSB4X/ACTB/CAV1/B2M/IFI16/JUN 7 GO:0072028 nephron morphogenesis 4/504 76/18722 0.148459930291791 0.369248709043553 PDGFRB/GPC3/PKD2/PBX1 4 GO:2000379 positive regulation of reactive oxygen species metabolic process 4/504 76/18722 0.148459930291791 0.369248709043553 THBS1/PDGFRB/AGTR1/TSPO 4 GO:0006892 post-Golgi vesicle-mediated transport 5/504 104/18722 0.149168864710761 0.370580557505281 MYO1B/SPTBN1/PREPL/ARL3/MACF1 5 GO:1901890 positive regulation of cell junction assembly 5/504 104/18722 0.149168864710761 0.370580557505281 THY1/CAV1/LIMS1/FERMT2/MAP4K4 5 GO:0010565 regulation of cellular ketone metabolic process 6/504 133/18722 0.149816878670341 0.371974156047859 ATP2B4/CAV1/EGR1/LPGAT1/NCOR2/ELOVL5 6 GO:0001961 positive regulation of cytokine-mediated signaling pathway 3/504 50/18722 0.1512576623714 0.37424666549681 GAS6/AXL/IL1R1 3 GO:0018023 peptidyl-lysine trimethylation 3/504 50/18722 0.1512576623714 0.37424666549681 KMT2E/ATRX/KMT2A 3 GO:0019083 viral transcription 3/504 50/18722 0.1512576623714 0.37424666549681 IFITM3/ZFP36/JUN 3 GO:0051646 mitochondrion localization 3/504 50/18722 0.1512576623714 0.37424666549681 MAP1B/MEF2A/ARMCX3 3 GO:0071825 protein-lipid complex subunit organization 3/504 50/18722 0.1512576623714 0.37424666549681 PLA2G2A/AGTR1/LIPG 3 GO:1904036 negative regulation of epithelial cell apoptotic process 3/504 50/18722 0.1512576623714 0.37424666549681 SEMA5A/GAS6/MDK 3 GO:0043547 positive regulation of GTPase activity 10/504 255/18722 0.151746712366187 0.375239410845321 THY1/CHN1/ARHGAP42/ITGB1/LIMS1/CAV2/FERMT2/MAP4K4/MYO9A/RAB11FIP2 10 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 5/504 105/18722 0.153413594532082 0.376383677321478 EPS8/RHOQ/CDC42EP3/NCKAP1/PIK3R1 5 GO:0000380 alternative mRNA splicing, via spliceosome 4/504 77/18722 0.153496782956891 0.376383677321478 MBNL2/MBNL1/DDX17/RBFOX2 4 GO:0140056 organelle localization by membrane tethering 4/504 77/18722 0.153496782956891 0.376383677321478 SYTL2/CAV2/VMP1/CTBP2 4 GO:1901983 regulation of protein acetylation 4/504 77/18722 0.153496782956891 0.376383677321478 MYOCD/SOX4/TAOK1/KMT2A 4 GO:0042552 myelination 6/504 134/18722 0.1535368095312 0.376383677321478 PMP22/HGF/FAM126A/SBF2/PTEN/MARVELD1 6 GO:0050777 negative regulation of immune response 8/504 194/18722 0.153784262360514 0.376383677321478 COL3A1/A2M/SERPING1/IFI16/HTRA1/ISG15/AHR/STAT2 8 GO:0007204 positive regulation of cytosolic calcium ion concentration 12/504 319/18722 0.154166884086988 0.376383677321478 THY1/AGTR1/EDNRA/PDGFRA/LPAR1/SLC8A1/EDNRB/ATP2B4/CAV1/PKD2/CALM2/NPTN 12 GO:0021952 central nervous system projection neuron axonogenesis 2/504 26/18722 0.15423538941959 0.376383677321478 CDH11/NFIB 2 GO:0034114 regulation of heterotypic cell-cell adhesion 2/504 26/18722 0.15423538941959 0.376383677321478 THY1/MYADM 2 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 2/504 26/18722 0.15423538941959 0.376383677321478 MAP1B/ARMCX3 2 GO:0042634 regulation of hair cycle 2/504 26/18722 0.15423538941959 0.376383677321478 TGFB2/CLOCK 2 GO:0047497 mitochondrion transport along microtubule 2/504 26/18722 0.15423538941959 0.376383677321478 MAP1B/ARMCX3 2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 2/504 26/18722 0.15423538941959 0.376383677321478 CD81/CMTM3 2 GO:0060037 pharyngeal system development 2/504 26/18722 0.15423538941959 0.376383677321478 TGFB2/BMPR2 2 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 2/504 26/18722 0.15423538941959 0.376383677321478 PKD2/CALM2 2 GO:0060352 cell adhesion molecule production 2/504 26/18722 0.15423538941959 0.376383677321478 MYOCD/CAV1 2 GO:0060669 embryonic placenta morphogenesis 2/504 26/18722 0.15423538941959 0.376383677321478 IGF2/ZFP36L1 2 GO:0070193 synaptonemal complex organization 2/504 26/18722 0.15423538941959 0.376383677321478 HSPA2/P3H4 2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 2/504 26/18722 0.15423538941959 0.376383677321478 ATP2B4/AKAP13 2 GO:0072273 metanephric nephron morphogenesis 2/504 26/18722 0.15423538941959 0.376383677321478 PDGFRB/PKD2 2 GO:1902656 calcium ion import into cytosol 2/504 26/18722 0.15423538941959 0.376383677321478 SLC8A1/ATP2B4 2 GO:1904861 excitatory synapse assembly 2/504 26/18722 0.15423538941959 0.376383677321478 NPTN/PTEN 2 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 2/504 26/18722 0.15423538941959 0.376383677321478 MYOCD/EFEMP2 2 GO:0046651 lymphocyte proliferation 11/504 288/18722 0.155871937453055 0.380160267543896 IGFBP2/LRRC32/TWSG1/MEF2C/CD81/IL6ST/IGF2/PRKAR1A/MSN/AHR/SOS1 11 GO:0016311 dephosphorylation 15/504 417/18722 0.157498959459457 0.383544221423186 ITGA1/PDGFRB/PLPP1/INPP4B/DLC1/TGFB2/NT5DC2/MEF2C/PPM1K/CALM2/HSP90B1/ROCK2/PTEN/PTPRA/PPP1R12A 15 GO:0032873 negative regulation of stress-activated MAPK cascade 3/504 51/18722 0.1577082136767 0.383544221423186 FOXO1/ZMYND11/AIDA 3 GO:0045104 intermediate filament cytoskeleton organization 3/504 51/18722 0.1577082136767 0.383544221423186 VIM/DST/MACF1 3 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 3/504 51/18722 0.1577082136767 0.383544221423186 FOXO1/ZMYND11/AIDA 3 GO:0071622 regulation of granulocyte chemotaxis 3/504 51/18722 0.1577082136767 0.383544221423186 THBS1/RARRES2/MDK 3 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 4/504 78/18722 0.15859728396349 0.384611915082855 AKAP12/EDNRA/FLNA/LPAR1 4 GO:0034637 cellular carbohydrate biosynthetic process 4/504 78/18722 0.15859728396349 0.384611915082855 ENPP1/EXT1/DYRK2/IGF2 4 GO:0043297 apical junction assembly 4/504 78/18722 0.15859728396349 0.384611915082855 MTDH/VCL/TJP1/ROCK2 4 GO:0043537 negative regulation of blood vessel endothelial cell migration 4/504 78/18722 0.15859728396349 0.384611915082855 THBS1/MEF2C/ATP2B4/STARD13 4 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 4/504 78/18722 0.15859728396349 0.384611915082855 THBS1/HDAC7/STARD13/AKT3 4 GO:0051480 regulation of cytosolic calcium ion concentration 13/504 353/18722 0.158876585740949 0.385070703840656 THY1/AGTR1/EDNRA/PDGFRA/LPAR1/SLC8A1/EDNRB/ATP2B4/CAV1/CAV2/PKD2/CALM2/NPTN 13 GO:0031348 negative regulation of defense response 10/504 258/18722 0.159749499780805 0.386966900546134 WFDC1/HGF/A2M/MDK/SERPING1/IFI16/HTRA1/ZFP36/ISG15/STAT2 10 GO:0022408 negative regulation of cell-cell adhesion 8/504 196/18722 0.159980866077503 0.387307785127007 PRKG1/LRRC32/PAG1/TWSG1/JAG1/MDK/MYADM/PRKAR1A 8 GO:0050727 regulation of inflammatory response 14/504 386/18722 0.160552578216749 0.38847178183475 PLA2G2A/WFDC1/AGTR1/HGF/OSMR/CD81/MDK/EDNRB/IL1R1/TMSB4X/ETS1/IL6ST/ZFP36/CLOCK 14 GO:0034504 protein localization to nucleus 11/504 290/18722 0.160936581976417 0.388910578396359 COL1A1/APOD/FLNA/TXNIP/PKIG/SYNE1/FERMT2/WWTR1/STAT3/PIK3R1/KPNA3 11 GO:0007272 ensheathment of neurons 6/504 136/18722 0.161097992923369 0.388910578396359 PMP22/HGF/FAM126A/SBF2/PTEN/MARVELD1 6 GO:0008366 axon ensheathment 6/504 136/18722 0.161097992923369 0.388910578396359 PMP22/HGF/FAM126A/SBF2/PTEN/MARVELD1 6 GO:1900180 regulation of protein localization to nucleus 6/504 136/18722 0.161097992923369 0.388910578396359 APOD/FLNA/PKIG/FERMT2/WWTR1/PIK3R1 6 GO:0005976 polysaccharide metabolic process 5/504 107/18722 0.162051496286529 0.390489946390858 ENPP1/EXT1/IL6ST/DYRK2/IGF2 5 GO:0051341 regulation of oxidoreductase activity 5/504 107/18722 0.162051496286529 0.390489946390858 AOC3/AGTR1/ATP2B4/CAV1/DDAH2 5 GO:0032943 mononuclear cell proliferation 11/504 291/18722 0.163499538084778 0.390489946390858 IGFBP2/LRRC32/TWSG1/MEF2C/CD81/IL6ST/IGF2/PRKAR1A/MSN/AHR/SOS1 11 GO:0001895 retina homeostasis 4/504 79/18722 0.163759546883156 0.390489946390858 ACTB/B2M/HSPB1/ACTG1 4 GO:0006023 aminoglycan biosynthetic process 4/504 79/18722 0.163759546883156 0.390489946390858 PDGFRB/EXT1/DSEL/UGDH 4 GO:0006446 regulation of translational initiation 4/504 79/18722 0.163759546883156 0.390489946390858 EIF4G3/HSPB1/EIF4EBP1/EIF4EBP2 4 GO:0051279 regulation of release of sequestered calcium ion into cytosol 4/504 79/18722 0.163759546883156 0.390489946390858 THY1/SLC8A1/PKD2/CALM2 4 GO:0003272 endocardial cushion formation 2/504 27/18722 0.16376269223787 0.390489946390858 TBX2/TGFB2 2 GO:0003401 axis elongation 2/504 27/18722 0.16376269223787 0.390489946390858 SPRY1/PTK7 2 GO:0006783 heme biosynthetic process 2/504 27/18722 0.16376269223787 0.390489946390858 TSPO/NFE2L1 2 GO:0007026 negative regulation of microtubule depolymerization 2/504 27/18722 0.16376269223787 0.390489946390858 MAP1B/TAOK1 2 GO:0010586 miRNA metabolic process 2/504 27/18722 0.16376269223787 0.390489946390858 KCNQ1OT1/DDX17 2 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 2/504 27/18722 0.16376269223787 0.390489946390858 SLC8A1/CALM2 2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 2/504 27/18722 0.16376269223787 0.390489946390858 HSPA2/PBX1 2 GO:0032703 negative regulation of interleukin-2 production 2/504 27/18722 0.16376269223787 0.390489946390858 HDAC7/ZFP36 2 GO:0032967 positive regulation of collagen biosynthetic process 2/504 27/18722 0.16376269223787 0.390489946390858 PDGFRB/VIM 2 GO:0034505 tooth mineralization 2/504 27/18722 0.16376269223787 0.390489946390858 COL1A1/FOXO1 2 GO:0042104 positive regulation of activated T cell proliferation 2/504 27/18722 0.16376269223787 0.390489946390858 IGFBP2/IGF2 2 GO:0046174 polyol catabolic process 2/504 27/18722 0.16376269223787 0.390489946390858 INPP4B/PTEN 2 GO:0060142 regulation of syncytium formation by plasma membrane fusion 2/504 27/18722 0.16376269223787 0.390489946390858 EHD2/ADAM9 2 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 2/504 27/18722 0.16376269223787 0.390489946390858 DCN/ADGRA2 2 GO:1902883 negative regulation of response to oxidative stress 2/504 27/18722 0.16376269223787 0.390489946390858 HGF/NCOA7 2 GO:0035196 production of miRNAs involved in gene silencing by miRNA 3/504 52/18722 0.164241899965359 0.3909780716167 MYOCD/NCOR2/STAT3 3 GO:0045010 actin nucleation 3/504 52/18722 0.164241899965359 0.3909780716167 LMOD1/GSN/NCKAP1 3 GO:0045103 intermediate filament-based process 3/504 52/18722 0.164241899965359 0.3909780716167 VIM/DST/MACF1 3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 7/504 167/18722 0.164866510832361 0.392197975468782 CDH11/PCDH18/NEXN/ITGB1/PALLD/FAT1/NPTN 7 GO:0000086 G2/M transition of mitotic cell cycle 6/504 137/18722 0.164937926964054 0.392197975468782 FHL1/HSPA2/CALM2/PBX1/TAOK1/NBN 6 GO:0006260 DNA replication 10/504 260/18722 0.165198307196654 0.392380415036856 NFIA/NFIB/NFIC/PTMS/REV3L/ZBTB38/JUN/POLK/ATRX/NBN 10 GO:0051091 positive regulation of DNA-binding transcription factor activity 10/504 260/18722 0.165198307196654 0.392380415036856 DDR2/MYOCD/WNT2/MTDH/CAV1/HIPK2/ARID5B/CLOCK/STAT3/PTEN 10 GO:0033157 regulation of intracellular protein transport 9/504 229/18722 0.166234891993589 0.394623163049225 APOD/FLNA/GAS6/IFI27/CD81/PKIG/PIK3R1/STOM/TOMM7 9 GO:0001818 negative regulation of cytokine production 13/504 357/18722 0.168156291558323 0.398962706179186 THBS1/APOD/LRRC32/HGF/GAS6/AXL/TGFB2/TWSG1/TMSB4X/TSPO/HDAC7/ZFP36/NPTN 13 GO:0032273 positive regulation of protein polymerization 6/504 138/18722 0.168816521430983 0.400306879064701 MAP1B/LMOD1/GSN/CDC42EP3/NCKAP1/ARL3 6 GO:0009314 response to radiation 16/504 456/18722 0.170687849349655 0.403632618912227 COL3A1/CRYAB/TIMP1/CCND2/MMP2/CRIP1/ITGB1/EXT1/EGR1/IFI16/RHOB/CLOCK/JUN/POLK/PIK3R1/NPTN 16 GO:0031330 negative regulation of cellular catabolic process 10/504 262/18722 0.170736176283313 0.403632618912227 HGF/TIMP1/ATP2B4/TIMP2/TIMP3/TSPO/HIPK2/QSOX1/ZFP36/STAT3 10 GO:0016925 protein sumoylation 3/504 53/18722 0.170854592414517 0.403632618912227 EGR1/HDAC7/ZMIZ1 3 GO:0031279 regulation of cyclase activity 3/504 53/18722 0.170854592414517 0.403632618912227 EDNRB/TIMP2/CALM2 3 GO:1903202 negative regulation of oxidative stress-induced cell death 3/504 53/18722 0.170854592414517 0.403632618912227 HGF/HSPB1/NCOA7 3 GO:0002456 T cell mediated immunity 5/504 109/18722 0.170880273253503 0.403632618912227 JAG1/CD81/IL1R1/B2M/AHR 5 GO:0043266 regulation of potassium ion transport 5/504 109/18722 0.170880273253503 0.403632618912227 FHL1/FLNA/ITGB1/CAV1/PTEN 5 GO:0010948 negative regulation of cell cycle process 11/504 294/18722 0.171309037794738 0.404421833423711 FHL1/KANK2/SOX4/PKD2/ZFP36L1/PRKAR1A/CLOCK/ATRX/PTEN/TAOK1/NBN 11 GO:0009152 purine ribonucleotide biosynthetic process 7/504 169/18722 0.171869244293851 0.405520309700512 GUCY1A2/ADCY3/PAPSS2/TMSB4X/ELOVL5/STAT3/ACLY 7 GO:0000303 response to superoxide 2/504 28/18722 0.173390762155104 0.406194477351293 FBLN5/SOD3 2 GO:0001945 lymph vessel development 2/504 28/18722 0.173390762155104 0.406194477351293 NR2F2/BMPR2 2 GO:0002675 positive regulation of acute inflammatory response 2/504 28/18722 0.173390762155104 0.406194477351293 OSMR/IL6ST 2 GO:0010575 positive regulation of vascular endothelial growth factor production 2/504 28/18722 0.173390762155104 0.406194477351293 SULF2/IL6ST 2 GO:0010714 positive regulation of collagen metabolic process 2/504 28/18722 0.173390762155104 0.406194477351293 PDGFRB/VIM 2 GO:0034123 positive regulation of toll-like receptor signaling pathway 2/504 28/18722 0.173390762155104 0.406194477351293 CAV1/PJA2 2 GO:0045671 negative regulation of osteoclast differentiation 2/504 28/18722 0.173390762155104 0.406194477351293 FBN1/PIK3R1 2 GO:0061082 myeloid leukocyte cytokine production 2/504 28/18722 0.173390762155104 0.406194477351293 SPON2/TGFB2 2 GO:0071280 cellular response to copper ion 2/504 28/18722 0.173390762155104 0.406194477351293 MT1E/MAP1LC3A 2 GO:0086011 membrane repolarization during action potential 2/504 28/18722 0.173390762155104 0.406194477351293 FLNA/CAV1 2 GO:0090344 negative regulation of cell aging 2/504 28/18722 0.173390762155104 0.406194477351293 PTEN/AKT3 2 GO:1903672 positive regulation of sprouting angiogenesis 2/504 28/18722 0.173390762155104 0.406194477351293 TJP1/JAK1 2 GO:1903779 regulation of cardiac conduction 2/504 28/18722 0.173390762155104 0.406194477351293 SLC8A1/ATP2B4 2 GO:0000422 autophagy of mitochondrion 4/504 81/18722 0.174261727548501 0.407118841888871 CTSK/TSPO/MAP1LC3A/TOMM7 4 GO:0021954 central nervous system neuron development 4/504 81/18722 0.174261727548501 0.407118841888871 CDH11/NFIB/PTEN/ZMIZ1 4 GO:0051817 modulation of process of other organism involved in symbiotic interaction 4/504 81/18722 0.174261727548501 0.407118841888871 IFI27/CAV2/JUN/STOM 4 GO:0061726 mitochondrion disassembly 4/504 81/18722 0.174261727548501 0.407118841888871 CTSK/TSPO/MAP1LC3A/TOMM7 4 GO:2000106 regulation of leukocyte apoptotic process 4/504 81/18722 0.174261727548501 0.407118841888871 GAS6/AXL/MEF2C/PTEN 4 GO:0018958 phenol-containing compound metabolic process 5/504 110/18722 0.175363536044372 0.409245433925505 HAND2/CTSK/TGFB2/ZEB2/MAOA 5 GO:0061387 regulation of extent of cell growth 5/504 110/18722 0.175363536044372 0.409245433925505 MAP1B/SEMA5A/DPYSL2/MACF1/BMPR2 5 GO:0009952 anterior/posterior pattern specification 8/504 201/18722 0.17597152426005 0.410440132731001 HES4/WNT2/NR2F2/GPC3/TSHZ1/HIPK2/BMPR2/PBX1 8 GO:0048193 Golgi vesicle transport 11/504 296/18722 0.176614230178495 0.411659313273701 MYO1B/COPZ2/GAS1/SPTBN1/SEC31A/SEC23A/PREPL/SEC24D/ARL3/BCAP29/MACF1 11 GO:0007292 female gamete generation 6/504 140/18722 0.176686913303058 0.411659313273701 PDE3A/MDK/PRKAR1A/ADAMTS1/ZMIZ1/SOS1 6 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 3/504 54/18722 0.177542189248594 0.41185546941327 THBS1/AGTR1/SEMA5A 3 GO:0006584 catecholamine metabolic process 3/504 54/18722 0.177542189248594 0.41185546941327 HAND2/TGFB2/MAOA 3 GO:0009712 catechol-containing compound metabolic process 3/504 54/18722 0.177542189248594 0.41185546941327 HAND2/TGFB2/MAOA 3 GO:0030520 intracellular estrogen receptor signaling pathway 3/504 54/18722 0.177542189248594 0.41185546941327 KANK2/DDX17/RBFOX2 3 GO:0031050 dsRNA processing 3/504 54/18722 0.177542189248594 0.41185546941327 MYOCD/NCOR2/STAT3 3 GO:0032330 regulation of chondrocyte differentiation 3/504 54/18722 0.177542189248594 0.41185546941327 MAF/MDK/SOX6 3 GO:0070918 production of small RNA involved in gene silencing by RNA 3/504 54/18722 0.177542189248594 0.41185546941327 MYOCD/NCOR2/STAT3 3 GO:0086002 cardiac muscle cell action potential involved in contraction 3/504 54/18722 0.177542189248594 0.41185546941327 GJC1/FLNA/CAV1 3 GO:0009913 epidermal cell differentiation 8/504 202/18722 0.179252454151511 0.415371874506186 TXNIP/JAG1/PALLD/ZFP36L1/ZFP36/ROCK2/ADAM9/FOSL2 8 GO:0032388 positive regulation of intracellular transport 8/504 202/18722 0.179252454151511 0.415371874506186 EHD2/FLNA/GAS6/CD81/MSN/PIK3R1/STOM/TOMM7 8 GO:0002312 B cell activation involved in immune response 4/504 82/18722 0.179597794545349 0.415946545307467 LGALS1/NOTCH2/XBP1/NBN 4 GO:0034341 response to interferon-gamma 6/504 141/18722 0.180677292306321 0.418219972927904 VIM/IFITM2/IFITM3/IFITM1/JAK1/ACTG1 6 GO:0031647 regulation of protein stability 11/504 298/18722 0.181996881460138 0.421046385749414 CRYAB/FLNA/HIP1/CD81/SOX4/GSN/CRTAP/PARVA/PIK3R1/PTEN/TOMM7 11 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 2/504 29/18722 0.183107303691824 0.421107378189001 ZFP36/TNRC6B 2 GO:0000305 response to oxygen radical 2/504 29/18722 0.183107303691824 0.421107378189001 FBLN5/SOD3 2 GO:0009310 amine catabolic process 2/504 29/18722 0.183107303691824 0.421107378189001 ATP2B4/MAOA 2 GO:0010592 positive regulation of lamellipodium assembly 2/504 29/18722 0.183107303691824 0.421107378189001 NCKAP1/PIK3R1 2 GO:0010955 negative regulation of protein processing 2/504 29/18722 0.183107303691824 0.421107378189001 THBS1/GAS1 2 GO:0033028 myeloid cell apoptotic process 2/504 29/18722 0.183107303691824 0.421107378189001 MEF2C/PTEN 2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 2/504 29/18722 0.183107303691824 0.421107378189001 CCND2/PKD2 2 GO:0048679 regulation of axon regeneration 2/504 29/18722 0.183107303691824 0.421107378189001 FLNA/PTEN 2 GO:0051654 establishment of mitochondrion localization 2/504 29/18722 0.183107303691824 0.421107378189001 MAP1B/ARMCX3 2 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 2/504 29/18722 0.183107303691824 0.421107378189001 CAV1/PTEN 2 GO:1903318 negative regulation of protein maturation 2/504 29/18722 0.183107303691824 0.421107378189001 THBS1/GAS1 2 GO:0001755 neural crest cell migration 3/504 55/18722 0.18430062086231 0.422857995288511 SEMA5A/HAND2/EDNRB 3 GO:0003229 ventricular cardiac muscle tissue development 3/504 55/18722 0.18430062086231 0.422857995288511 ADAMTS9/TPM1/TGFB2 3 GO:0010676 positive regulation of cellular carbohydrate metabolic process 3/504 55/18722 0.18430062086231 0.422857995288511 NNMT/DYRK2/IGF2 3 GO:0048016 inositol phosphate-mediated signaling 3/504 55/18722 0.18430062086231 0.422857995288511 LMCD1/DYRK2/ATP2B4 3 GO:0002526 acute inflammatory response 5/504 112/18722 0.184462275501471 0.422857995288511 OSMR/EXT1/EDNRB/IL6ST/STAT3 5 GO:1901222 regulation of NIK/NF-kappaB signaling 5/504 112/18722 0.184462275501471 0.422857995288511 UACA/TMSB4X/LIMS1/ACTN4/HDAC7 5 GO:0031623 receptor internalization 5/504 113/18722 0.189075499955301 0.43296870916881 RAMP1/CD81/ITGB1/CAV1/MKLN1 5 GO:0044106 cellular amine metabolic process 5/504 113/18722 0.189075499955301 0.43296870916881 NNMT/HAND2/TGFB2/ATP2B4/MAOA 5 GO:0006112 energy reserve metabolic process 4/504 84/18722 0.190430173637158 0.435370857116947 ENPP1/IL6ST/DYRK2/IGF2 4 GO:0006970 response to osmotic stress 4/504 84/18722 0.190430173637158 0.435370857116947 MYLK/TSPO/PKD2/ZFP36L1 4 GO:0061157 mRNA destabilization 4/504 84/18722 0.190430173637158 0.435370857116947 ZFP36L1/ZFP36/ROCK2/TNRC6B 4 GO:0031334 positive regulation of protein-containing complex assembly 9/504 237/18722 0.190589225502818 0.435501476242535 MAP1B/LMOD1/GSN/CDC42EP3/FERMT2/NCKAP1/ISG15/ARL3/MSN 9 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3/504 56/18722 0.191125854554107 0.436028177527869 ZFP36L1/ZFP36/TNRC6B 3 GO:0001658 branching involved in ureteric bud morphogenesis 3/504 56/18722 0.191125854554107 0.436028177527869 GPC3/PKD2/PBX1 3 GO:0002711 positive regulation of T cell mediated immunity 3/504 56/18722 0.191125854554107 0.436028177527869 CD81/IL1R1/B2M 3 GO:0017038 protein import 8/504 206/18722 0.192639910398576 0.436349548776094 APOD/FLNA/TXNIP/PKIG/STAT3/PIK3R1/TOMM7/KPNA3 8 GO:0000132 establishment of mitotic spindle orientation 2/504 30/18722 0.192900607919036 0.436349548776094 ITGB1/SPRY1 2 GO:0003299 muscle hypertrophy in response to stress 2/504 30/18722 0.192900607919036 0.436349548776094 FOXO1/ATP2B4 2 GO:0007202 activation of phospholipase C activity 2/504 30/18722 0.192900607919036 0.436349548776094 EDNRA/LPAR1 2 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 2/504 30/18722 0.192900607919036 0.436349548776094 SLC8A1/CALM2 2 GO:0014887 cardiac muscle adaptation 2/504 30/18722 0.192900607919036 0.436349548776094 FOXO1/ATP2B4 2 GO:0014898 cardiac muscle hypertrophy in response to stress 2/504 30/18722 0.192900607919036 0.436349548776094 FOXO1/ATP2B4 2 GO:0045577 regulation of B cell differentiation 2/504 30/18722 0.192900607919036 0.436349548776094 ZFP36L1/XBP1 2 GO:0046825 regulation of protein export from nucleus 2/504 30/18722 0.192900607919036 0.436349548776094 GAS6/IFI27 2 GO:0051125 regulation of actin nucleation 2/504 30/18722 0.192900607919036 0.436349548776094 GSN/NCKAP1 2 GO:0051491 positive regulation of filopodium assembly 2/504 30/18722 0.192900607919036 0.436349548776094 RHOQ/PIK3R1 2 GO:0070498 interleukin-1-mediated signaling pathway 2/504 30/18722 0.192900607919036 0.436349548776094 IL1R1/EGR1 2 GO:0140058 neuron projection arborization 2/504 30/18722 0.192900607919036 0.436349548776094 MYO9A/MACF1 2 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 2/504 30/18722 0.192900607919036 0.436349548776094 XBP1/PIK3R1 2 GO:1902751 positive regulation of cell cycle G2/M phase transition 2/504 30/18722 0.192900607919036 0.436349548776094 HSPA2/PBX1 2 GO:1903579 negative regulation of ATP metabolic process 2/504 30/18722 0.192900607919036 0.436349548776094 TSPO/STAT3 2 GO:0002244 hematopoietic progenitor cell differentiation 5/504 114/18722 0.193729773939848 0.437993293145487 PDGFRA/EXT1/SOX4/CITED2/SOS1 5 GO:0002709 regulation of T cell mediated immunity 4/504 85/18722 0.19592257928065 0.442248907166517 CD81/IL1R1/B2M/AHR 4 GO:0010507 negative regulation of autophagy 4/504 85/18722 0.19592257928065 0.442248907166517 HGF/TSPO/QSOX1/STAT3 4 GO:0071277 cellular response to calcium ion 4/504 85/18722 0.19592257928065 0.442248907166517 MEF2C/PKD2/MEF2A/SLC25A24 4 GO:0051289 protein homotetramerization 3/504 57/18722 0.198013898889662 0.446262336474432 B2M/PKD2/GLS 3 GO:0060042 retina morphogenesis in camera-type eye 3/504 57/18722 0.198013898889662 0.446262336474432 THY1/HIPK2/MAN2A1 3 GO:0060760 positive regulation of response to cytokine stimulus 3/504 57/18722 0.198013898889662 0.446262336474432 GAS6/AXL/IL1R1 3 GO:1901989 positive regulation of cell cycle phase transition 5/504 115/18722 0.198423944689879 0.446950719905035 CCND2/HSPA2/KMT2E/ADAMTS1/PBX1 5 GO:0010675 regulation of cellular carbohydrate metabolic process 6/504 146/18722 0.201151699219906 0.452660120812133 IGFBP4/NNMT/ENPP1/DYRK2/IGF2/STAT3 6 GO:0032413 negative regulation of ion transmembrane transporter activity 4/504 86/18722 0.201463183467091 0.452660120812133 CAV1/PKD2/CALM2/PTEN 4 GO:0034103 regulation of tissue remodeling 4/504 86/18722 0.201463183467091 0.452660120812133 DDR2/HAND2/MDK/ROCK2 4 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 10/504 273/18722 0.202708667127255 0.452660120812133 CDH11/PCDH18/SPARCL1/NEXN/TGFB2/ITGB1/PALLD/MYADM/FAT1/NPTN 10 GO:0001782 B cell homeostasis 2/504 31/18722 0.202759529893382 0.452660120812133 MEF2C/SOS1 2 GO:0006301 postreplication repair 2/504 31/18722 0.202759529893382 0.452660120812133 REV3L/POLK 2 GO:0006779 porphyrin-containing compound biosynthetic process 2/504 31/18722 0.202759529893382 0.452660120812133 TSPO/NFE2L1 2 GO:0031114 regulation of microtubule depolymerization 2/504 31/18722 0.202759529893382 0.452660120812133 MAP1B/TAOK1 2 GO:0033014 tetrapyrrole biosynthetic process 2/504 31/18722 0.202759529893382 0.452660120812133 TSPO/NFE2L1 2 GO:0033238 regulation of cellular amine metabolic process 2/504 31/18722 0.202759529893382 0.452660120812133 NNMT/ATP2B4 2 GO:0061099 negative regulation of protein tyrosine kinase activity 2/504 31/18722 0.202759529893382 0.452660120812133 THY1/CAV1 2 GO:0070528 protein kinase C signaling 2/504 31/18722 0.202759529893382 0.452660120812133 AKAP12/MYADM 2 GO:0071480 cellular response to gamma radiation 2/504 31/18722 0.202759529893382 0.452660120812133 CRYAB/EGR1 2 GO:1900027 regulation of ruffle assembly 2/504 31/18722 0.202759529893382 0.452660120812133 EPS8/CAV1 2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/504 31/18722 0.202759529893382 0.452660120812133 HGF/PEA15 2 GO:1905144 response to acetylcholine 2/504 31/18722 0.202759529893382 0.452660120812133 ATP2B4/ROCK2 2 GO:1905145 cellular response to acetylcholine 2/504 31/18722 0.202759529893382 0.452660120812133 ATP2B4/ROCK2 2 GO:0018107 peptidyl-threonine phosphorylation 5/504 116/18722 0.203156850620989 0.453310299061874 DYRK2/CDC42BPA/HIPK2/CALM2/ROCK2 5 GO:0035725 sodium ion transmembrane transport 7/504 178/18722 0.204896009344677 0.455907095972678 FXYD1/SLMAP/SLC8A1/ATP2B4/ACTN4/PKD2/STOM 7 GO:0002763 positive regulation of myeloid leukocyte differentiation 3/504 58/18722 0.204960807714373 0.455907095972678 ZFP36L1/NOTCH2/JUN 3 GO:0018208 peptidyl-proline modification 3/504 58/18722 0.204960807714373 0.455907095972678 FKBP10/CRTAP/FKBP14 3 GO:0043525 positive regulation of neuron apoptotic process 3/504 58/18722 0.204960807714373 0.455907095972678 ITGA1/TGFB2/JUN 3 GO:0045604 regulation of epidermal cell differentiation 3/504 58/18722 0.204960807714373 0.455907095972678 ZFP36L1/ZFP36/ROCK2 3 GO:1902808 positive regulation of cell cycle G1/S phase transition 3/504 58/18722 0.204960807714373 0.455907095972678 CCND2/KMT2E/ADAMTS1 3 GO:0045862 positive regulation of proteolysis 13/504 372/18722 0.205268077329106 0.456288412930724 PCOLCE/ANTXR1/DLC1/UACA/HIP1/MYH9/CAV1/GSN/IFI16/ROCK2/ADAM9/STAT3/PTEN 13 GO:1902850 microtubule cytoskeleton organization involved in mitosis 6/504 147/18722 0.205345803432198 0.456288412930724 FLNA/ITGB1/SPRY1/MAP9/TACC1/MAP4 6 GO:0061014 positive regulation of mRNA catabolic process 4/504 87/18722 0.207050024189397 0.459358646605033 ZFP36L1/ZFP36/ROCK2/TNRC6B 4 GO:1900182 positive regulation of protein localization to nucleus 4/504 87/18722 0.207050024189397 0.459358646605033 FLNA/FERMT2/WWTR1/PIK3R1 4 GO:1903578 regulation of ATP metabolic process 4/504 87/18722 0.207050024189397 0.459358646605033 COX7A1/TMSB4X/TSPO/STAT3 4 GO:0002702 positive regulation of production of molecular mediator of immune response 5/504 117/18722 0.207927322325862 0.460826477333199 SPON2/CD81/IL1R1/B2M/XBP1 5 GO:0072676 lymphocyte migration 5/504 117/18722 0.207927322325862 0.460826477333199 APOD/GAS6/EXT1/MSN/CD99 5 GO:0007416 synapse assembly 7/504 179/18722 0.208708152983042 0.461838393421303 MAP1B/FARP1/PDLIM5/MEF2C/PLXND1/NPTN/PTEN 7 GO:0007626 locomotory behavior 7/504 179/18722 0.208708152983042 0.461838393421303 MEIS1/CCND2/EPS8/EGR1/HIPK2/ZFHX3/PTEN 7 GO:0010950 positive regulation of endopeptidase activity 7/504 179/18722 0.208708152983042 0.461838393421303 DLC1/UACA/HIP1/GSN/IFI16/ROCK2/STAT3 7 GO:0010212 response to ionizing radiation 6/504 148/18722 0.209571183149485 0.463028782625518 CRYAB/CCND2/EGR1/IFI16/RHOB/CLOCK 6 GO:0044272 sulfur compound biosynthetic process 6/504 148/18722 0.209571183149485 0.463028782625518 PAPSS2/EXT1/DSEL/UGDH/ELOVL5/ACLY 6 GO:0044839 cell cycle G2/M phase transition 6/504 148/18722 0.209571183149485 0.463028782625518 FHL1/HSPA2/CALM2/PBX1/TAOK1/NBN 6 GO:0030100 regulation of endocytosis 8/504 211/18722 0.209938238015151 0.463600047048445 AXL/HIP1/GPC3/CAV1/B2M/ITSN1/STON1/MKLN1 8 GO:0021885 forebrain cell migration 3/504 59/18722 0.211962683832862 0.464852434279066 AXL/LAMB1/ZMIZ1 3 GO:0032768 regulation of monooxygenase activity 3/504 59/18722 0.211962683832862 0.464852434279066 ATP2B4/CAV1/DDAH2 3 GO:0043407 negative regulation of MAP kinase activity 3/504 59/18722 0.211962683832862 0.464852434279066 CAV1/SPRY1/AIDA 3 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 3/504 59/18722 0.211962683832862 0.464852434279066 PDGFRB/PDGFRA/PIK3R1 3 GO:0048278 vesicle docking 3/504 59/18722 0.211962683832862 0.464852434279066 SYTL2/CAV2/CTBP2 3 GO:0051568 histone H3-K4 methylation 3/504 59/18722 0.211962683832862 0.464852434279066 NNMT/KMT2E/KMT2A 3 GO:2001258 negative regulation of cation channel activity 3/504 59/18722 0.211962683832862 0.464852434279066 CAV1/PKD2/CALM2 3 GO:0003338 metanephros morphogenesis 2/504 32/18722 0.212673466878264 0.464852434279066 PDGFRB/PKD2 2 GO:0010743 regulation of macrophage derived foam cell differentiation 2/504 32/18722 0.212673466878264 0.464852434279066 PLA2G2A/AGTR1 2 GO:0021799 cerebral cortex radially oriented cell migration 2/504 32/18722 0.212673466878264 0.464852434279066 LAMB1/ZMIZ1 2 GO:0042044 fluid transport 2/504 32/18722 0.212673466878264 0.464852434279066 EXT1/EDNRB 2 GO:0045761 regulation of adenylate cyclase activity 2/504 32/18722 0.212673466878264 0.464852434279066 EDNRB/TIMP2 2 GO:0045879 negative regulation of smoothened signaling pathway 2/504 32/18722 0.212673466878264 0.464852434279066 ENPP1/GPC3 2 GO:0046856 phosphatidylinositol dephosphorylation 2/504 32/18722 0.212673466878264 0.464852434279066 INPP4B/PTEN 2 GO:0048841 regulation of axon extension involved in axon guidance 2/504 32/18722 0.212673466878264 0.464852434279066 SEMA5A/BMPR2 2 GO:0071875 adrenergic receptor signaling pathway 2/504 32/18722 0.212673466878264 0.464852434279066 ATP2B4/AKAP13 2 GO:0072337 modified amino acid transport 2/504 32/18722 0.212673466878264 0.464852434279066 MGST1/SLC38A2 2 GO:0090140 regulation of mitochondrial fission 2/504 32/18722 0.212673466878264 0.464852434279066 DCN/STAT2 2 GO:1900745 positive regulation of p38MAPK cascade 2/504 32/18722 0.212673466878264 0.464852434279066 HAND2/PJA2 2 GO:0050779 RNA destabilization 4/504 88/18722 0.212681139484103 0.464852434279066 ZFP36L1/ZFP36/ROCK2/TNRC6B 4 GO:0045834 positive regulation of lipid metabolic process 6/504 149/18722 0.213827052749111 0.46711809631746 PDGFRB/AGTR1/PDGFRA/CD81/LPGAT1/ELOVL5 6 GO:0099504 synaptic vesicle cycle 7/504 181/18722 0.216411356601265 0.472522088276548 ACTB/PREPL/ITSN1/STON1/CTBP2/PTEN/ACTG1 7 GO:0043583 ear development 8/504 213/18722 0.21702253130945 0.473614543557345 SPARC/PDGFRB/CTHRC1/TGFB2/JAG1/MAF/TSHZ1/PTK7 8 GO:0010906 regulation of glucose metabolic process 5/504 119/18722 0.217576252156654 0.474580564300858 IGFBP4/NNMT/ENPP1/DYRK2/IGF2 5 GO:0031349 positive regulation of defense response 10/504 278/18722 0.218031312993114 0.475330510418151 PLA2G2A/AGTR1/OSMR/MEF2C/CD81/MDK/ETS1/IL6ST/IFI16/CLOCK 10 GO:1900407 regulation of cellular response to oxidative stress 4/504 89/18722 0.218354569291962 0.475535574582765 HGF/FBLN5/HSPB1/NCOA7 4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 3/504 60/18722 0.219015682372778 0.475535574582765 FHL1/TAOK1/NBN 3 GO:0031638 zymogen activation 3/504 60/18722 0.219015682372778 0.475535574582765 THBS1/C1R/IFI16 3 GO:0033866 nucleoside bisphosphate biosynthetic process 3/504 60/18722 0.219015682372778 0.475535574582765 PAPSS2/ELOVL5/ACLY 3 GO:0034030 ribonucleoside bisphosphate biosynthetic process 3/504 60/18722 0.219015682372778 0.475535574582765 PAPSS2/ELOVL5/ACLY 3 GO:0034033 purine nucleoside bisphosphate biosynthetic process 3/504 60/18722 0.219015682372778 0.475535574582765 PAPSS2/ELOVL5/ACLY 3 GO:0055008 cardiac muscle tissue morphogenesis 3/504 60/18722 0.219015682372778 0.475535574582765 WNT2/TPM1/TGFB2 3 GO:0061951 establishment of protein localization to plasma membrane 3/504 60/18722 0.219015682372778 0.475535574582765 SPTBN1/PREPL/MACF1 3 GO:0009260 ribonucleotide biosynthetic process 7/504 182/18722 0.220301278626835 0.478083983530962 GUCY1A2/ADCY3/PAPSS2/TMSB4X/ELOVL5/STAT3/ACLY 7 GO:0002761 regulation of myeloid leukocyte differentiation 5/504 120/18722 0.222452341049933 0.480458574439473 FBN1/ZFP36L1/NOTCH2/JUN/PIK3R1 5 GO:0010737 protein kinase A signaling 2/504 33/18722 0.222632337325101 0.480458574439473 AKAP12/PJA2 2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 2/504 33/18722 0.222632337325101 0.480458574439473 EMILIN1/EPN2 2 GO:0031116 positive regulation of microtubule polymerization 2/504 33/18722 0.222632337325101 0.480458574439473 MAP1B/ARL3 2 GO:0040020 regulation of meiotic nuclear division 2/504 33/18722 0.222632337325101 0.480458574439473 PDE3A/PRKAR1A 2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 2/504 33/18722 0.222632337325101 0.480458574439473 PDGFRB/PDGFRA 2 GO:0050901 leukocyte tethering or rolling 2/504 33/18722 0.222632337325101 0.480458574439473 ITGB1/EXT1 2 GO:0110110 positive regulation of animal organ morphogenesis 2/504 33/18722 0.222632337325101 0.480458574439473 WNT2/SPRY1 2 GO:1900181 negative regulation of protein localization to nucleus 2/504 33/18722 0.222632337325101 0.480458574439473 APOD/PKIG 2 GO:1901380 negative regulation of potassium ion transmembrane transport 2/504 33/18722 0.222632337325101 0.480458574439473 CAV1/PTEN 2 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 2/504 33/18722 0.222632337325101 0.480458574439473 CCND2/PKD2 2 GO:0042475 odontogenesis of dentin-containing tooth 4/504 90/18722 0.224068357245584 0.483313523730631 HAND2/PDGFRA/FOXO1/HTRA1 4 GO:0006900 vesicle budding from membrane 3/504 61/18722 0.226116013849433 0.486992806037615 SEC31A/SEC23A/SEC24D 3 GO:0060998 regulation of dendritic spine development 3/504 61/18722 0.226116013849433 0.486992806037615 MEF2C/ITSN1/PTEN 3 GO:0090342 regulation of cell aging 3/504 61/18722 0.226116013849433 0.486992806037615 B2M/PTEN/AKT3 3 GO:0031056 regulation of histone modification 6/504 152/18722 0.226769651837809 0.487680446737827 NNMT/MYOCD/IGF2/KMT2E/ATRX/KMT2A 6 GO:0042177 negative regulation of protein catabolic process 5/504 121/18722 0.227361259106669 0.487680446737827 FLNA/TIMP1/TIMP2/TIMP3/HIPK2 5 GO:0048706 embryonic skeletal system development 5/504 121/18722 0.227361259106669 0.487680446737827 COL1A1/PDGFRA/SULF2/EXT1/PBX1 5 GO:0006470 protein dephosphorylation 10/504 281/18722 0.227442065806146 0.487680446737827 ITGA1/PDGFRB/DLC1/PPM1K/CALM2/HSP90B1/ROCK2/PTEN/PTPRA/PPP1R12A 10 GO:0046394 carboxylic acid biosynthetic process 11/504 314/18722 0.227659272241814 0.487680446737827 GATM/RBP1/LIPG/UGDH/ATP2B4/LPGAT1/GLS/XBP1/ELOVL5/PLOD2/ACLY 11 GO:1901988 negative regulation of cell cycle phase transition 9/504 249/18722 0.229775611670009 0.487680446737827 FHL1/KANK2/SOX4/PKD2/ZFP36L1/CLOCK/PTEN/TAOK1/NBN 9 GO:0002065 columnar/cuboidal epithelial cell differentiation 4/504 91/18722 0.229820552384929 0.487680446737827 EXT1/IL6ST/SOX4/CLOCK 4 GO:0045582 positive regulation of T cell differentiation 4/504 91/18722 0.229820552384929 0.487680446737827 MDK/SOX4/XBP1/ZMIZ1 4 GO:0050868 negative regulation of T cell activation 5/504 122/18722 0.232301812065741 0.487680446737827 LRRC32/PAG1/TWSG1/MDK/PRKAR1A 5 GO:0051208 sequestering of calcium ion 5/504 122/18722 0.232301812065741 0.487680446737827 THY1/SLC8A1/PKD2/CALM2/HSP90B1 5 GO:1990266 neutrophil migration 5/504 122/18722 0.232301812065741 0.487680446737827 ITGA1/TGFB2/MDK/IL1R1/CD99 5 GO:0001662 behavioral fear response 2/504 34/18722 0.232626560589703 0.487680446737827 MEF2C/MDK 2 GO:0007095 mitotic G2 DNA damage checkpoint signaling 2/504 34/18722 0.232626560589703 0.487680446737827 TAOK1/NBN 2 GO:0007616 long-term memory 2/504 34/18722 0.232626560589703 0.487680446737827 CCND2/PJA2 2 GO:0010614 negative regulation of cardiac muscle hypertrophy 2/504 34/18722 0.232626560589703 0.487680446737827 FOXO1/ATP2B4 2 GO:0014072 response to isoquinoline alkaloid 2/504 34/18722 0.232626560589703 0.487680446737827 MAP1LC3A/PEA15 2 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 2/504 34/18722 0.232626560589703 0.487680446737827 SLC8A1/CALM2 2 GO:0043276 anoikis 2/504 34/18722 0.232626560589703 0.487680446737827 ITGB1/CAV1 2 GO:0043278 response to morphine 2/504 34/18722 0.232626560589703 0.487680446737827 MAP1LC3A/PEA15 2 GO:0048536 spleen development 2/504 34/18722 0.232626560589703 0.487680446737827 CITED2/PBX1 2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 2/504 34/18722 0.232626560589703 0.487680446737827 AGTR1/LPAR1 2 GO:0055094 response to lipoprotein particle 2/504 34/18722 0.232626560589703 0.487680446737827 CD81/ITGB1 2 GO:0086019 cell-cell signaling involved in cardiac conduction 2/504 34/18722 0.232626560589703 0.487680446737827 GJC1/FLNA 2 GO:2000352 negative regulation of endothelial cell apoptotic process 2/504 34/18722 0.232626560589703 0.487680446737827 SEMA5A/GAS6 2 GO:0007588 excretion 3/504 62/18722 0.233259946947083 0.487680446737827 AGTR1/MDK/EDNRB 3 GO:0019933 cAMP-mediated signaling 3/504 62/18722 0.233259946947083 0.487680446737827 PDE3A/EIF4EBP2/AHR 3 GO:0032613 interleukin-10 production 3/504 62/18722 0.233259946947083 0.487680446737827 HGF/ISG15/STAT3 3 GO:0032623 interleukin-2 production 3/504 62/18722 0.233259946947083 0.487680446737827 SPTBN1/HDAC7/ZFP36 3 GO:0032653 regulation of interleukin-10 production 3/504 62/18722 0.233259946947083 0.487680446737827 HGF/ISG15/STAT3 3 GO:0032663 regulation of interleukin-2 production 3/504 62/18722 0.233259946947083 0.487680446737827 SPTBN1/HDAC7/ZFP36 3 GO:0046148 pigment biosynthetic process 3/504 62/18722 0.233259946947083 0.487680446737827 ZEB2/TSPO/NFE2L1 3 GO:0046824 positive regulation of nucleocytoplasmic transport 3/504 62/18722 0.233259946947083 0.487680446737827 FLNA/GAS6/PIK3R1 3 GO:0046847 filopodium assembly 3/504 62/18722 0.233259946947083 0.487680446737827 RHOQ/MYO10/PIK3R1 3 GO:0060135 maternal process involved in female pregnancy 3/504 62/18722 0.233259946947083 0.487680446737827 NR2F2/CITED2/BMPR2 3 GO:0060675 ureteric bud morphogenesis 3/504 62/18722 0.233259946947083 0.487680446737827 GPC3/PKD2/PBX1 3 GO:1902750 negative regulation of cell cycle G2/M phase transition 3/504 62/18722 0.233259946947083 0.487680446737827 FHL1/TAOK1/NBN 3 GO:0016053 organic acid biosynthetic process 11/504 316/18722 0.23366664938733 0.487680446737827 GATM/RBP1/LIPG/UGDH/ATP2B4/LPGAT1/GLS/XBP1/ELOVL5/PLOD2/ACLY 11 GO:0044262 cellular carbohydrate metabolic process 10/504 283/18722 0.233801753103439 0.487680446737827 IGFBP4/NNMT/ENPP1/INPP4B/EXT1/IL6ST/DYRK2/IGF2/STAT3/PTEN 10 GO:0070509 calcium ion import 4/504 92/18722 0.235609210801561 0.487680446737827 PDGFRB/SLC8A1/ATP2B4/PKD2 4 GO:0006959 humoral immune response 11/504 317/18722 0.236693132004239 0.487680446737827 SPON2/RARRES2/C1R/CFH/C1S/A2M/MEF2C/CD81/SERPING1/NOTCH2/CFD 11 GO:0071482 cellular response to light stimulus 5/504 123/18722 0.237272803405127 0.487680446737827 TIMP1/MMP2/CRIP1/POLK/PIK3R1 5 GO:0001553 luteinization 1/504 10/18722 0.238875538268727 0.487680446737827 PDGFRA 1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 1/504 10/18722 0.238875538268727 0.487680446737827 CD81 1 GO:0002524 hypersensitivity 1/504 10/18722 0.238875538268727 0.487680446737827 EXT1 1 GO:0003056 regulation of vascular associated smooth muscle contraction 1/504 10/18722 0.238875538268727 0.487680446737827 ARHGAP42 1 GO:0006171 cAMP biosynthetic process 1/504 10/18722 0.238875538268727 0.487680446737827 ADCY3 1 GO:0009750 response to fructose 1/504 10/18722 0.238875538268727 0.487680446737827 XBP1 1 GO:0010728 regulation of hydrogen peroxide biosynthetic process 1/504 10/18722 0.238875538268727 0.487680446737827 STAT3 1 GO:0014041 regulation of neuron maturation 1/504 10/18722 0.238875538268727 0.487680446737827 EDNRB 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/504 10/18722 0.238875538268727 0.487680446737827 THBS1 1 GO:0016081 synaptic vesicle docking 1/504 10/18722 0.238875538268727 0.487680446737827 CTBP2 1 GO:0017085 response to insecticide 1/504 10/18722 0.238875538268727 0.487680446737827 MAP1B 1 GO:0019614 catechol-containing compound catabolic process 1/504 10/18722 0.238875538268727 0.487680446737827 MAOA 1 GO:0031642 negative regulation of myelination 1/504 10/18722 0.238875538268727 0.487680446737827 PTEN 1 GO:0031915 positive regulation of synaptic plasticity 1/504 10/18722 0.238875538268727 0.487680446737827 MAP1B 1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway 1/504 10/18722 0.238875538268727 0.487680446737827 NNMT 1 GO:0034756 regulation of iron ion transport 1/504 10/18722 0.238875538268727 0.487680446737827 B2M 1 GO:0035768 endothelial cell chemotaxis to fibroblast growth factor 1/504 10/18722 0.238875538268727 0.487680446737827 FGFR1 1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway 1/504 10/18722 0.238875538268727 0.487680446737827 SULF2 1 GO:0036109 alpha-linolenic acid metabolic process 1/504 10/18722 0.238875538268727 0.487680446737827 ELOVL5 1 GO:0042045 epithelial fluid transport 1/504 10/18722 0.238875538268727 0.487680446737827 EDNRB 1 GO:0042424 catecholamine catabolic process 1/504 10/18722 0.238875538268727 0.487680446737827 MAOA 1 GO:0042711 maternal behavior 1/504 10/18722 0.238875538268727 0.487680446737827 PTEN 1 GO:0043084 penile erection 1/504 10/18722 0.238875538268727 0.487680446737827 EDNRB 1 GO:0044848 biological phase 1/504 10/18722 0.238875538268727 0.487680446737827 TGFB2 1 GO:0045348 positive regulation of MHC class II biosynthetic process 1/504 10/18722 0.238875538268727 0.487680446737827 XBP1 1 GO:0045792 negative regulation of cell size 1/504 10/18722 0.238875538268727 0.487680446737827 PTEN 1 GO:0045835 negative regulation of meiotic nuclear division 1/504 10/18722 0.238875538268727 0.487680446737827 PRKAR1A 1 GO:0048262 determination of dorsal/ventral asymmetry 1/504 10/18722 0.238875538268727 0.487680446737827 AIDA 1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1/504 10/18722 0.238875538268727 0.487680446737827 CALM2 1 GO:0051351 positive regulation of ligase activity 1/504 10/18722 0.238875538268727 0.487680446737827 TMSB4X 1 GO:0051918 negative regulation of fibrinolysis 1/504 10/18722 0.238875538268727 0.487680446737827 THBS1 1 GO:0060068 vagina development 1/504 10/18722 0.238875538268727 0.487680446737827 AXL 1 GO:0060736 prostate gland growth 1/504 10/18722 0.238875538268727 0.487680446737827 PTEN 1 GO:0060947 cardiac vascular smooth muscle cell differentiation 1/504 10/18722 0.238875538268727 0.487680446737827 MYOCD 1 GO:0061140 lung secretory cell differentiation 1/504 10/18722 0.238875538268727 0.487680446737827 NFIB 1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1/504 10/18722 0.238875538268727 0.487680446737827 MAP4K4 1 GO:0061299 retina vasculature morphogenesis in camera-type eye 1/504 10/18722 0.238875538268727 0.487680446737827 COL4A1 1 GO:0070099 regulation of chemokine-mediated signaling pathway 1/504 10/18722 0.238875538268727 0.487680446737827 SLIT3 1 GO:0070561 vitamin D receptor signaling pathway 1/504 10/18722 0.238875538268727 0.487680446737827 KANK2 1 GO:0071803 positive regulation of podosome assembly 1/504 10/18722 0.238875538268727 0.487680446737827 MSN 1 GO:0072124 regulation of glomerular mesangial cell proliferation 1/504 10/18722 0.238875538268727 0.487680446737827 EGR1 1 GO:0072178 nephric duct morphogenesis 1/504 10/18722 0.238875538268727 0.487680446737827 GPC3 1 GO:0090179 planar cell polarity pathway involved in neural tube closure 1/504 10/18722 0.238875538268727 0.487680446737827 PTK7 1 GO:0090527 actin filament reorganization 1/504 10/18722 0.238875538268727 0.487680446737827 GSN 1 GO:0090647 modulation of age-related behavioral decline 1/504 10/18722 0.238875538268727 0.487680446737827 B2M 1 GO:0097105 presynaptic membrane assembly 1/504 10/18722 0.238875538268727 0.487680446737827 PTEN 1 GO:0097278 complement-dependent cytotoxicity 1/504 10/18722 0.238875538268727 0.487680446737827 CFH 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/504 10/18722 0.238875538268727 0.487680446737827 ITSN1 1 GO:0098917 retrograde trans-synaptic signaling 1/504 10/18722 0.238875538268727 0.487680446737827 FARP1 1 GO:0099532 synaptic vesicle endosomal processing 1/504 10/18722 0.238875538268727 0.487680446737827 ITSN1 1 GO:1901203 positive regulation of extracellular matrix assembly 1/504 10/18722 0.238875538268727 0.487680446737827 EMILIN1 1 GO:1902855 regulation of non-motile cilium assembly 1/504 10/18722 0.238875538268727 0.487680446737827 MAP4 1 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 1/504 10/18722 0.238875538268727 0.487680446737827 ROCK2 1 GO:1903867 extraembryonic membrane development 1/504 10/18722 0.238875538268727 0.487680446737827 HTRA1 1 GO:1904350 regulation of protein catabolic process in the vacuole 1/504 10/18722 0.238875538268727 0.487680446737827 CD81 1 GO:1904668 positive regulation of ubiquitin protein ligase activity 1/504 10/18722 0.238875538268727 0.487680446737827 PTEN 1 GO:1905383 protein localization to presynapse 1/504 10/18722 0.238875538268727 0.487680446737827 HSPB1 1 GO:1905456 regulation of lymphoid progenitor cell differentiation 1/504 10/18722 0.238875538268727 0.487680446737827 SOS1 1 GO:1905941 positive regulation of gonad development 1/504 10/18722 0.238875538268727 0.487680446737827 CITED2 1 GO:2000018 regulation of male gonad development 1/504 10/18722 0.238875538268727 0.487680446737827 CITED2 1 GO:2000121 regulation of removal of superoxide radicals 1/504 10/18722 0.238875538268727 0.487680446737827 FBLN5 1 GO:2000288 positive regulation of myoblast proliferation 1/504 10/18722 0.238875538268727 0.487680446737827 MALAT1 1 GO:2000510 positive regulation of dendritic cell chemotaxis 1/504 10/18722 0.238875538268727 0.487680446737827 GAS6 1 GO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor 1/504 10/18722 0.238875538268727 0.487680446737827 FGFR1 1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation 1/504 10/18722 0.238875538268727 0.487680446737827 NCKAP1 1 GO:2000659 regulation of interleukin-1-mediated signaling pathway 1/504 10/18722 0.238875538268727 0.487680446737827 IL1R1 1 GO:2000726 negative regulation of cardiac muscle cell differentiation 1/504 10/18722 0.238875538268727 0.487680446737827 SOX6 1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/504 10/18722 0.238875538268727 0.487680446737827 GSN 1 GO:0072503 cellular divalent inorganic cation homeostasis 16/504 486/18722 0.239115946107982 0.48793812689561 THY1/AGTR1/EDNRA/PDGFRA/MT1E/LPAR1/SLC8A1/EDNRB/ATP2B4/SLC39A6/CAV1/CAV2/PKD2/CALM2/HSP90B1/NPTN 16 GO:0070661 leukocyte proliferation 11/504 318/18722 0.239734488499562 0.488966811149704 IGFBP2/LRRC32/TWSG1/MEF2C/CD81/IL6ST/IGF2/PRKAR1A/MSN/AHR/SOS1 11 GO:0050854 regulation of antigen receptor-mediated signaling pathway 3/504 63/18722 0.240443811031983 0.489478992158009 THY1/CD81/CMTM3 3 GO:0072171 mesonephric tubule morphogenesis 3/504 63/18722 0.240443811031983 0.489478992158009 GPC3/PKD2/PBX1 3 GO:2000242 negative regulation of reproductive process 3/504 63/18722 0.240443811031983 0.489478992158009 TIMP1/MYH9/PRKAR1A 3 GO:2000756 regulation of peptidyl-lysine acetylation 3/504 63/18722 0.240443811031983 0.489478992158009 MYOCD/SOX4/KMT2A 3 GO:0090398 cellular senescence 4/504 93/18722 0.241432397212632 0.491257444423609 TBX2/B2M/SMC6/AKT3 4 GO:0000731 DNA synthesis involved in DNA repair 2/504 35/18722 0.242647037359533 0.491621996508907 REV3L/POLK 2 GO:0002209 behavioral defense response 2/504 35/18722 0.242647037359533 0.491621996508907 MEF2C/MDK 2 GO:0010765 positive regulation of sodium ion transport 2/504 35/18722 0.242647037359533 0.491621996508907 FXYD1/ACTN4 2 GO:0032814 regulation of natural killer cell activation 2/504 35/18722 0.242647037359533 0.491621996508907 GAS6/AXL 2 GO:0040001 establishment of mitotic spindle localization 2/504 35/18722 0.242647037359533 0.491621996508907 ITGB1/SPRY1 2 GO:0042462 eye photoreceptor cell development 2/504 35/18722 0.242647037359533 0.491621996508907 THY1/TUG1 2 GO:0046640 regulation of alpha-beta T cell proliferation 2/504 35/18722 0.242647037359533 0.491621996508907 TWSG1/CD81 2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2/504 35/18722 0.242647037359533 0.491621996508907 HDAC7/AKT3 2 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 2/504 35/18722 0.242647037359533 0.491621996508907 SLC8A1/CALM2 2 GO:0048839 inner ear development 7/504 188/18722 0.244140661460055 0.494413766075267 SPARC/PDGFRB/CTHRC1/TGFB2/JAG1/MAF/PTK7 7 GO:0009895 negative regulation of catabolic process 11/504 320/18722 0.245860842897245 0.497661478777797 HGF/FLNA/TIMP1/ATP2B4/TIMP2/TIMP3/TSPO/HIPK2/QSOX1/ZFP36/STAT3 11 GO:0002690 positive regulation of leukocyte chemotaxis 4/504 94/18722 0.247288186465653 0.498712660326618 THBS1/RARRES2/GAS6/MDK 4 GO:0019080 viral gene expression 4/504 94/18722 0.247288186465653 0.498712660326618 IFITM3/ZFP36/JUN/MAN2A1 4 GO:0051702 biological process involved in interaction with symbiont 4/504 94/18722 0.247288186465653 0.498712660326618 IFI27/CAV2/JUN/STOM 4 GO:0018210 peptidyl-threonine modification 5/504 125/18722 0.247301308936807 0.498712660326618 DYRK2/CDC42BPA/HIPK2/CALM2/ROCK2 5 GO:0071621 granulocyte chemotaxis 5/504 125/18722 0.247301308936807 0.498712660326618 ITGA1/THBS1/RARRES2/TGFB2/MDK 5 GO:0030888 regulation of B cell proliferation 3/504 64/18722 0.247663998411674 0.498712660326618 MEF2C/CD81/AHR 3 GO:0045670 regulation of osteoclast differentiation 3/504 64/18722 0.247663998411674 0.498712660326618 FBN1/NOTCH2/PIK3R1 3 GO:0045995 regulation of embryonic development 3/504 64/18722 0.247663998411674 0.498712660326618 LAMA4/LAMA2/WNT2 3 GO:0046854 phosphatidylinositol phosphate biosynthetic process 3/504 64/18722 0.247663998411674 0.498712660326618 INPP4B/FAM126A/PIK3R1 3 GO:0050771 negative regulation of axonogenesis 3/504 64/18722 0.247663998411674 0.498712660326618 THY1/SEMA5A/PTEN 3 GO:0098930 axonal transport 3/504 64/18722 0.247663998411674 0.498712660326618 DST/HSPB1/ARMCX3 3 GO:0051250 negative regulation of lymphocyte activation 6/504 157/18722 0.248875500460761 0.499240596842165 LRRC32/AXL/PAG1/TWSG1/MDK/PRKAR1A 6 GO:0006816 calcium ion transport 14/504 422/18722 0.248999917428487 0.499240596842165 MYLK/PDGFRB/THY1/GAS6/RAMP1/SLC8A1/HSPA2/ATP2B4/CAV1/TSPO/PKD2/CALM2/VMP1/AHNAK 14 GO:0046390 ribose phosphate biosynthetic process 7/504 190/18722 0.252263306491854 0.499240596842165 GUCY1A2/ADCY3/PAPSS2/TMSB4X/ELOVL5/STAT3/ACLY 7 GO:0032874 positive regulation of stress-activated MAPK cascade 5/504 126/18722 0.252356426362033 0.499240596842165 HAND2/TGFB2/HIPK2/PJA2/TAOK1 5 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2/504 36/18722 0.252685130768412 0.499240596842165 THBS1/B2M 2 GO:0003203 endocardial cushion morphogenesis 2/504 36/18722 0.252685130768412 0.499240596842165 TBX2/TGFB2 2 GO:0008207 C21-steroid hormone metabolic process 2/504 36/18722 0.252685130768412 0.499240596842165 EGR1/TSPO 2 GO:0010923 negative regulation of phosphatase activity 2/504 36/18722 0.252685130768412 0.499240596842165 TGFB2/ROCK2 2 GO:0038179 neurotrophin signaling pathway 2/504 36/18722 0.252685130768412 0.499240596842165 SPRY1/SOS1 2 GO:0042119 neutrophil activation 2/504 36/18722 0.252685130768412 0.499240596842165 PLA2G2A/KMT2E 2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 2/504 36/18722 0.252685130768412 0.499240596842165 HIP1/SOS1 2 GO:0060338 regulation of type I interferon-mediated signaling pathway 2/504 36/18722 0.252685130768412 0.499240596842165 ISG15/STAT2 2 GO:0071402 cellular response to lipoprotein particle stimulus 2/504 36/18722 0.252685130768412 0.499240596842165 CD81/ITGB1 2 GO:0086010 membrane depolarization during action potential 2/504 36/18722 0.252685130768412 0.499240596842165 SLMAP/SLC8A1 2 GO:0097009 energy homeostasis 2/504 36/18722 0.252685130768412 0.499240596842165 FOXO1/STAT3 2 GO:0006942 regulation of striated muscle contraction 4/504 95/18722 0.253174664975143 0.499240596842165 SLC8A1/CAV1/CALM2/NR4A1 4 GO:0050764 regulation of phagocytosis 4/504 95/18722 0.253174664975143 0.499240596842165 MFGE8/GAS6/CNN2/PTEN 4 GO:1990823 response to leukemia inhibitory factor 4/504 95/18722 0.253174664975143 0.499240596842165 EXT1/EPS8/ARID5B/CTBP2 4 GO:0045682 regulation of epidermis development 3/504 65/18722 0.254916966354333 0.499240596842165 ZFP36L1/ZFP36/ROCK2 3 GO:0070936 protein K48-linked ubiquitination 3/504 65/18722 0.254916966354333 0.499240596842165 IFI27/TTC3/UBE2E3 3 GO:0006164 purine nucleotide biosynthetic process 7/504 191/18722 0.25635495501142 0.499240596842165 GUCY1A2/ADCY3/PAPSS2/TMSB4X/ELOVL5/STAT3/ACLY 7 GO:0030217 T cell differentiation 9/504 257/18722 0.257423125068317 0.499240596842165 MDK/SOX4/EGR1/B2M/ZFP36L1/XBP1/STAT3/ZMIZ1/SOS1 9 GO:0034620 cellular response to unfolded protein 4/504 96/18722 0.259089932092326 0.499240596842165 HSPA2/XBP1/ATF3/PIK3R1 4 GO:0042632 cholesterol homeostasis 4/504 96/18722 0.259089932092326 0.499240596842165 LIPG/CAV1/LIMA1/XBP1 4 GO:0001660 fever generation 1/504 11/18722 0.25937611162874 0.499240596842165 EDNRB 1 GO:0002357 defense response to tumor cell 1/504 11/18722 0.25937611162874 0.499240596842165 RBMS3 1 GO:0002604 regulation of dendritic cell antigen processing and presentation 1/504 11/18722 0.25937611162874 0.499240596842165 THBS1 1 GO:0003093 regulation of glomerular filtration 1/504 11/18722 0.25937611162874 0.499240596842165 GAS6 1 GO:0003139 secondary heart field specification 1/504 11/18722 0.25937611162874 0.499240596842165 MEF2C 1 GO:0003263 cardioblast proliferation 1/504 11/18722 0.25937611162874 0.499240596842165 HAND2 1 GO:0003264 regulation of cardioblast proliferation 1/504 11/18722 0.25937611162874 0.499240596842165 HAND2 1 GO:0006182 cGMP biosynthetic process 1/504 11/18722 0.25937611162874 0.499240596842165 GUCY1A2 1 GO:0010739 positive regulation of protein kinase A signaling 1/504 11/18722 0.25937611162874 0.499240596842165 AKAP12 1 GO:0010986 positive regulation of lipoprotein particle clearance 1/504 11/18722 0.25937611162874 0.499240596842165 LIPG 1 GO:0014854 response to inactivity 1/504 11/18722 0.25937611162874 0.499240596842165 FBXO32 1 GO:0018342 protein prenylation 1/504 11/18722 0.25937611162874 0.499240596842165 CHM 1 GO:0021860 pyramidal neuron development 1/504 11/18722 0.25937611162874 0.499240596842165 ZMIZ1 1 GO:0030210 heparin biosynthetic process 1/504 11/18722 0.25937611162874 0.499240596842165 EXT1 1 GO:0030432 peristalsis 1/504 11/18722 0.25937611162874 0.499240596842165 TBX2 1 GO:0032329 serine transport 1/504 11/18722 0.25937611162874 0.499240596842165 SLC38A2 1 GO:0033197 response to vitamin E 1/504 11/18722 0.25937611162874 0.499240596842165 COL1A1 1 GO:0033210 leptin-mediated signaling pathway 1/504 11/18722 0.25937611162874 0.499240596842165 STAT3 1 GO:0033483 gas homeostasis 1/504 11/18722 0.25937611162874 0.499240596842165 CAV1 1 GO:0033625 positive regulation of integrin activation 1/504 11/18722 0.25937611162874 0.499240596842165 FERMT2 1 GO:0033690 positive regulation of osteoblast proliferation 1/504 11/18722 0.25937611162874 0.499240596842165 CTHRC1 1 GO:0033860 regulation of NAD(P)H oxidase activity 1/504 11/18722 0.25937611162874 0.499240596842165 AGTR1 1 GO:0034115 negative regulation of heterotypic cell-cell adhesion 1/504 11/18722 0.25937611162874 0.499240596842165 MYADM 1 GO:0034975 protein folding in endoplasmic reticulum 1/504 11/18722 0.25937611162874 0.499240596842165 HSP90B1 1 GO:0035766 cell chemotaxis to fibroblast growth factor 1/504 11/18722 0.25937611162874 0.499240596842165 FGFR1 1 GO:0042135 neurotransmitter catabolic process 1/504 11/18722 0.25937611162874 0.499240596842165 MAOA 1 GO:0042416 dopamine biosynthetic process 1/504 11/18722 0.25937611162874 0.499240596842165 TGFB2 1 GO:0042670 retinal cone cell differentiation 1/504 11/18722 0.25937611162874 0.499240596842165 THY1 1 GO:0045793 positive regulation of cell size 1/504 11/18722 0.25937611162874 0.499240596842165 AKT3 1 GO:0046549 retinal cone cell development 1/504 11/18722 0.25937611162874 0.499240596842165 THY1 1 GO:0046598 positive regulation of viral entry into host cell 1/504 11/18722 0.25937611162874 0.499240596842165 LGALS1 1 GO:0046643 regulation of gamma-delta T cell activation 1/504 11/18722 0.25937611162874 0.499240596842165 SOX4 1 GO:0048096 chromatin-mediated maintenance of transcription 1/504 11/18722 0.25937611162874 0.499240596842165 ZMIZ1 1 GO:0048103 somatic stem cell division 1/504 11/18722 0.25937611162874 0.499240596842165 TGFB2 1 GO:0048680 positive regulation of axon regeneration 1/504 11/18722 0.25937611162874 0.499240596842165 FLNA 1 GO:0048853 forebrain morphogenesis 1/504 11/18722 0.25937611162874 0.499240596842165 PTEN 1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway 1/504 11/18722 0.25937611162874 0.499240596842165 SPRY1 1 GO:0051798 positive regulation of hair follicle development 1/504 11/18722 0.25937611162874 0.499240596842165 TGFB2 1 GO:0055015 ventricular cardiac muscle cell development 1/504 11/18722 0.25937611162874 0.499240596842165 MEF2A 1 GO:0060159 regulation of dopamine receptor signaling pathway 1/504 11/18722 0.25937611162874 0.499240596842165 CAV2 1 GO:0060174 limb bud formation 1/504 11/18722 0.25937611162874 0.499240596842165 SOX4 1 GO:0060746 parental behavior 1/504 11/18722 0.25937611162874 0.499240596842165 PTEN 1 GO:0061029 eyelid development in camera-type eye 1/504 11/18722 0.25937611162874 0.499240596842165 SOS1 1 GO:0070314 G1 to G0 transition 1/504 11/18722 0.25937611162874 0.499240596842165 ZNF503 1 GO:0070417 cellular response to cold 1/504 11/18722 0.25937611162874 0.499240596842165 FOXO1 1 GO:0070587 regulation of cell-cell adhesion involved in gastrulation 1/504 11/18722 0.25937611162874 0.499240596842165 MYADM 1 GO:0071313 cellular response to caffeine 1/504 11/18722 0.25937611162874 0.499240596842165 SLC8A1 1 GO:0071679 commissural neuron axon guidance 1/504 11/18722 0.25937611162874 0.499240596842165 NFIB 1 GO:0071888 macrophage apoptotic process 1/504 11/18722 0.25937611162874 0.499240596842165 MEF2C 1 GO:0072697 protein localization to cell cortex 1/504 11/18722 0.25937611162874 0.499240596842165 EPB41L2 1 GO:0075294 positive regulation by symbiont of entry into host 1/504 11/18722 0.25937611162874 0.499240596842165 LGALS1 1 GO:0075733 intracellular transport of virus 1/504 11/18722 0.25937611162874 0.499240596842165 KPNA3 1 GO:0086070 SA node cell to atrial cardiac muscle cell communication 1/504 11/18722 0.25937611162874 0.499240596842165 GJC1 1 GO:0090084 negative regulation of inclusion body assembly 1/504 11/18722 0.25937611162874 0.499240596842165 HSPA2 1 GO:0090178 regulation of establishment of planar polarity involved in neural tube closure 1/504 11/18722 0.25937611162874 0.499240596842165 PTK7 1 GO:0090394 negative regulation of excitatory postsynaptic potential 1/504 11/18722 0.25937611162874 0.499240596842165 PTEN 1 GO:0097090 presynaptic membrane organization 1/504 11/18722 0.25937611162874 0.499240596842165 PTEN 1 GO:0097354 prenylation 1/504 11/18722 0.25937611162874 0.499240596842165 CHM 1 GO:0099550 trans-synaptic signaling, modulating synaptic transmission 1/504 11/18722 0.25937611162874 0.499240596842165 NPTN 1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration 1/504 11/18722 0.25937611162874 0.499240596842165 SLC8A1 1 GO:0099624 atrial cardiac muscle cell membrane repolarization 1/504 11/18722 0.25937611162874 0.499240596842165 FLNA 1 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/504 11/18722 0.25937611162874 0.499240596842165 ATP2B4 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/504 11/18722 0.25937611162874 0.499240596842165 ATRX 1 GO:1900222 negative regulation of amyloid-beta clearance 1/504 11/18722 0.25937611162874 0.499240596842165 MYOCD 1 GO:1901862 negative regulation of muscle tissue development 1/504 11/18722 0.25937611162874 0.499240596842165 IGFBP5 1 GO:1902188 positive regulation of viral release from host cell 1/504 11/18722 0.25937611162874 0.499240596842165 CAV2 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/504 11/18722 0.25937611162874 0.499240596842165 TGFB2 1 GO:1903961 positive regulation of anion transmembrane transport 1/504 11/18722 0.25937611162874 0.499240596842165 ITGB1 1 GO:1904847 regulation of cell chemotaxis to fibroblast growth factor 1/504 11/18722 0.25937611162874 0.499240596842165 FGFR1 1 GO:1905150 regulation of voltage-gated sodium channel activity 1/504 11/18722 0.25937611162874 0.499240596842165 SLMAP 1 GO:1905522 negative regulation of macrophage migration 1/504 11/18722 0.25937611162874 0.499240596842165 EMILIN1 1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 1/504 11/18722 0.25937611162874 0.499240596842165 ATF3 1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 1/504 11/18722 0.25937611162874 0.499240596842165 TJP1 1 GO:2000615 regulation of histone H3-K9 acetylation 1/504 11/18722 0.25937611162874 0.499240596842165 KMT2A 1 GO:0055074 calcium ion homeostasis 15/504 460/18722 0.259583035935971 0.499413918304549 THY1/AGTR1/EDNRA/PDGFRA/CAMK2N1/LPAR1/SLC8A1/EDNRB/ATP2B4/CAV1/CAV2/PKD2/CALM2/HSP90B1/NPTN 15 GO:0016485 protein processing 8/504 225/18722 0.261275391956247 0.501185984667752 THBS1/C1R/CPXM1/ADAMTS2/GAS1/MYH9/GSN/IFI16 8 GO:0014015 positive regulation of gliogenesis 3/504 66/18722 0.262199238881389 0.501185984667752 MDK/IL6ST/TSPO 3 GO:0046626 regulation of insulin receptor signaling pathway 3/504 66/18722 0.262199238881389 0.501185984667752 ENPP1/IGF2/PIK3R1 3 GO:0071300 cellular response to retinoic acid 3/504 66/18722 0.262199238881389 0.501185984667752 COL1A1/WNT2/PTK7 3 GO:0072678 T cell migration 3/504 66/18722 0.262199238881389 0.501185984667752 APOD/MSN/CD99 3 GO:2000573 positive regulation of DNA biosynthetic process 3/504 66/18722 0.262199238881389 0.501185984667752 PDGFRB/PARM1/HGF 3 GO:0060402 calcium ion transport into cytosol 6/504 160/18722 0.262423895475248 0.501185984667752 THY1/SLC8A1/ATP2B4/CAV1/PKD2/CALM2 6 GO:0090316 positive regulation of intracellular protein transport 6/504 160/18722 0.262423895475248 0.501185984667752 FLNA/GAS6/CD81/PIK3R1/STOM/TOMM7 6 GO:0032612 interleukin-1 production 5/504 128/18722 0.262542405109325 0.501185984667752 GAS6/EGR1/IFI16/HSPB1/STAT3 5 GO:0032652 regulation of interleukin-1 production 5/504 128/18722 0.262542405109325 0.501185984667752 GAS6/EGR1/IFI16/HSPB1/STAT3 5 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 5/504 128/18722 0.262542405109325 0.501185984667752 HAND2/TGFB2/HIPK2/PJA2/TAOK1 5 GO:0003161 cardiac conduction system development 2/504 37/18722 0.262732648175934 0.501185984667752 SMAD5/NOTCH2 2 GO:0006904 vesicle docking involved in exocytosis 2/504 37/18722 0.262732648175934 0.501185984667752 SYTL2/CTBP2 2 GO:0016202 regulation of striated muscle tissue development 2/504 37/18722 0.262732648175934 0.501185984667752 MEF2C/IGF2 2 GO:0031112 positive regulation of microtubule polymerization or depolymerization 2/504 37/18722 0.262732648175934 0.501185984667752 MAP1B/ARL3 2 GO:0033120 positive regulation of RNA splicing 2/504 37/18722 0.262732648175934 0.501185984667752 SLC38A2/PIK3R1 2 GO:0060306 regulation of membrane repolarization 2/504 37/18722 0.262732648175934 0.501185984667752 FLNA/CAV1 2 GO:0060428 lung epithelium development 2/504 37/18722 0.262732648175934 0.501185984667752 WNT2/NFIB 2 GO:1902745 positive regulation of lamellipodium organization 2/504 37/18722 0.262732648175934 0.501185984667752 NCKAP1/PIK3R1 2 GO:0045927 positive regulation of growth 9/504 259/18722 0.26449916683379 0.504330629130203 MAP1B/SEMA5A/TBX2/WNT2/TGFB2/MEF2C/IGF2/MACF1/BMPR2 9 GO:0043255 regulation of carbohydrate biosynthetic process 4/504 97/18722 0.265032101409087 0.504446400588432 NNMT/ENPP1/DYRK2/IGF2 4 GO:0055092 sterol homeostasis 4/504 97/18722 0.265032101409087 0.504446400588432 LIPG/CAV1/LIMA1/XBP1 4 GO:1901216 positive regulation of neuron death 4/504 97/18722 0.265032101409087 0.504446400588432 ITGA1/TGFB2/EGR1/JUN 4 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 4/504 97/18722 0.265032101409087 0.504446400588432 THBS1/HGF/ZMYND11/PEA15 4 GO:0002285 lymphocyte activation involved in immune response 7/504 194/18722 0.268743883976871 0.511283444449318 LGALS1/CD81/MDK/NOTCH2/XBP1/STAT3/NBN 7 GO:0042130 negative regulation of T cell proliferation 3/504 67/18722 0.26950740834605 0.51250785752678 LRRC32/TWSG1/PRKAR1A 3 GO:0051604 protein maturation 10/504 294/18722 0.269896027743524 0.513018561631708 THBS1/C1R/CPXM1/ADAMTS2/GAS1/SOX4/MYH9/SERPINH1/GSN/IFI16 10 GO:0043473 pigmentation 4/504 98/18722 0.270999301997425 0.51424308012191 ENPP1/ZEB2/MEF2C/EDNRB 4 GO:1902882 regulation of response to oxidative stress 4/504 98/18722 0.270999301997425 0.51424308012191 HGF/FBLN5/HSPB1/NCOA7 4 GO:0021953 central nervous system neuron differentiation 6/504 162/18722 0.271561086483471 0.51424308012191 CDH11/NFIB/SOX4/B2M/PTEN/ZMIZ1 6 GO:0006882 cellular zinc ion homeostasis 2/504 38/18722 0.272781823589629 0.51424308012191 MT1E/SLC39A6 2 GO:0010742 macrophage derived foam cell differentiation 2/504 38/18722 0.272781823589629 0.51424308012191 PLA2G2A/AGTR1 2 GO:0032373 positive regulation of sterol transport 2/504 38/18722 0.272781823589629 0.51424308012191 LIPG/CAV1 2 GO:0032376 positive regulation of cholesterol transport 2/504 38/18722 0.272781823589629 0.51424308012191 LIPG/CAV1 2 GO:0046329 negative regulation of JNK cascade 2/504 38/18722 0.272781823589629 0.51424308012191 ZMYND11/AIDA 2 GO:0046633 alpha-beta T cell proliferation 2/504 38/18722 0.272781823589629 0.51424308012191 TWSG1/CD81 2 GO:0090077 foam cell differentiation 2/504 38/18722 0.272781823589629 0.51424308012191 PLA2G2A/AGTR1 2 GO:1901031 regulation of response to reactive oxygen species 2/504 38/18722 0.272781823589629 0.51424308012191 HGF/FBLN5 2 GO:1901186 positive regulation of ERBB signaling pathway 2/504 38/18722 0.272781823589629 0.51424308012191 HIP1/SOS1 2 GO:1903580 positive regulation of ATP metabolic process 2/504 38/18722 0.272781823589629 0.51424308012191 TMSB4X/STAT3 2 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 5/504 130/18722 0.272821419518643 0.51424308012191 GAS1/SEC31A/SEC23A/SEC24D/BCAP29 5 GO:0043467 regulation of generation of precursor metabolites and energy 5/504 130/18722 0.272821419518643 0.51424308012191 ENPP1/COX7A1/DYRK2/IGF2/STAT3 5 GO:0072331 signal transduction by p53 class mediator 6/504 163/18722 0.276158671859904 0.51424308012191 SOX4/DYRK2/HIPK2/IFI16/ATRX/NBN 6 GO:0034394 protein localization to cell surface 3/504 68/18722 0.276838136809789 0.51424308012191 FLNA/FBLN5/VCL 3 GO:1901607 alpha-amino acid biosynthetic process 3/504 68/18722 0.276838136809789 0.51424308012191 ATP2B4/GLS/PLOD2 3 GO:1904888 cranial skeletal system development 3/504 68/18722 0.276838136809789 0.51424308012191 PDGFRA/TGFB2/EXT1 3 GO:0030838 positive regulation of actin filament polymerization 4/504 99/18722 0.276989679585696 0.51424308012191 LMOD1/GSN/CDC42EP3/NCKAP1 4 GO:0051153 regulation of striated muscle cell differentiation 4/504 99/18722 0.276989679585696 0.51424308012191 MYOCD/MEF2C/SOX6/XBP1 4 GO:0060996 dendritic spine development 4/504 99/18722 0.276989679585696 0.51424308012191 PDLIM5/MEF2C/ITSN1/PTEN 4 GO:0006006 glucose metabolic process 7/504 196/18722 0.27709201765268 0.51424308012191 IGFBP4/NNMT/APOD/ENPP1/DYRK2/IGF2/ATF3 7 GO:0043393 regulation of protein binding 7/504 196/18722 0.27709201765268 0.51424308012191 CTHRC1/RAMP1/ACTB/CAV1/B2M/PLXND1/HIPK2 7 GO:0006661 phosphatidylinositol biosynthetic process 5/504 131/18722 0.277992843736925 0.51424308012191 INPP4B/FAM126A/PDGFA/PIK3R1/PTEN 5 GO:0002424 T cell mediated immune response to tumor cell 1/504 12/18722 0.279325576635374 0.51424308012191 AHR 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/504 12/18722 0.279325576635374 0.51424308012191 CD81 1 GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane 1/504 12/18722 0.279325576635374 0.51424308012191 SEC62 1 GO:0007614 short-term memory 1/504 12/18722 0.279325576635374 0.51424308012191 MDK 1 GO:0008228 opsonization 1/504 12/18722 0.279325576635374 0.51424308012191 SPON2 1 GO:0010587 miRNA catabolic process 1/504 12/18722 0.279325576635374 0.51424308012191 KCNQ1OT1 1 GO:0014831 gastro-intestinal system smooth muscle contraction 1/504 12/18722 0.279325576635374 0.51424308012191 SULF2 1 GO:0030202 heparin metabolic process 1/504 12/18722 0.279325576635374 0.51424308012191 EXT1 1 GO:0032780 negative regulation of ATPase activity 1/504 12/18722 0.279325576635374 0.51424308012191 CNN3 1 GO:0034086 maintenance of sister chromatid cohesion 1/504 12/18722 0.279325576635374 0.51424308012191 ATRX 1 GO:0034088 maintenance of mitotic sister chromatid cohesion 1/504 12/18722 0.279325576635374 0.51424308012191 ATRX 1 GO:0042117 monocyte activation 1/504 12/18722 0.279325576635374 0.51424308012191 ADAM9 1 GO:0048934 peripheral nervous system neuron differentiation 1/504 12/18722 0.279325576635374 0.51424308012191 HAND2 1 GO:0048935 peripheral nervous system neuron development 1/504 12/18722 0.279325576635374 0.51424308012191 HAND2 1 GO:0051340 regulation of ligase activity 1/504 12/18722 0.279325576635374 0.51424308012191 TMSB4X 1 GO:0060019 radial glial cell differentiation 1/504 12/18722 0.279325576635374 0.51424308012191 STAT3 1 GO:0060123 regulation of growth hormone secretion 1/504 12/18722 0.279325576635374 0.51424308012191 ITSN1 1 GO:0060134 prepulse inhibition 1/504 12/18722 0.279325576635374 0.51424308012191 PTEN 1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1/504 12/18722 0.279325576635374 0.51424308012191 EMILIN1 1 GO:0060788 ectodermal placode formation 1/504 12/18722 0.279325576635374 0.51424308012191 TBX2 1 GO:0060907 positive regulation of macrophage cytokine production 1/504 12/18722 0.279325576635374 0.51424308012191 SPON2 1 GO:0070586 cell-cell adhesion involved in gastrulation 1/504 12/18722 0.279325576635374 0.51424308012191 MYADM 1 GO:0071107 response to parathyroid hormone 1/504 12/18722 0.279325576635374 0.51424308012191 MEF2C 1 GO:0071257 cellular response to electrical stimulus 1/504 12/18722 0.279325576635374 0.51424308012191 PTEN 1 GO:0071472 cellular response to salt stress 1/504 12/18722 0.279325576635374 0.51424308012191 ZFP36L1 1 GO:0071697 ectodermal placode morphogenesis 1/504 12/18722 0.279325576635374 0.51424308012191 TBX2 1 GO:0071872 cellular response to epinephrine stimulus 1/504 12/18722 0.279325576635374 0.51424308012191 ATP2B4 1 GO:0072182 regulation of nephron tubule epithelial cell differentiation 1/504 12/18722 0.279325576635374 0.51424308012191 WWTR1 1 GO:0072520 seminiferous tubule development 1/504 12/18722 0.279325576635374 0.51424308012191 ATRX 1 GO:0072683 T cell extravasation 1/504 12/18722 0.279325576635374 0.51424308012191 CD99 1 GO:0072711 cellular response to hydroxyurea 1/504 12/18722 0.279325576635374 0.51424308012191 ATRX 1 GO:0086067 AV node cell to bundle of His cell communication 1/504 12/18722 0.279325576635374 0.51424308012191 GJC1 1 GO:0090331 negative regulation of platelet aggregation 1/504 12/18722 0.279325576635374 0.51424308012191 PRKG1 1 GO:0090557 establishment of endothelial intestinal barrier 1/504 12/18722 0.279325576635374 0.51424308012191 TJP1 1 GO:0098911 regulation of ventricular cardiac muscle cell action potential 1/504 12/18722 0.279325576635374 0.51424308012191 CAV1 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/504 12/18722 0.279325576635374 0.51424308012191 HGF 1 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance 1/504 12/18722 0.279325576635374 0.51424308012191 PLXND1 1 GO:1902563 regulation of neutrophil activation 1/504 12/18722 0.279325576635374 0.51424308012191 PLA2G2A 1 GO:1903441 protein localization to ciliary membrane 1/504 12/18722 0.279325576635374 0.51424308012191 ARL3 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/504 12/18722 0.279325576635374 0.51424308012191 MYOCD 1 GO:1904748 regulation of apoptotic process involved in development 1/504 12/18722 0.279325576635374 0.51424308012191 TGFB2 1 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation 1/504 12/18722 0.279325576635374 0.51424308012191 WNT2 1 GO:1905205 positive regulation of connective tissue replacement 1/504 12/18722 0.279325576635374 0.51424308012191 ROCK2 1 GO:1905245 regulation of aspartic-type peptidase activity 1/504 12/18722 0.279325576635374 0.51424308012191 ROCK2 1 GO:1990034 calcium ion export across plasma membrane 1/504 12/18722 0.279325576635374 0.51424308012191 CALM2 1 GO:2000105 positive regulation of DNA-dependent DNA replication 1/504 12/18722 0.279325576635374 0.51424308012191 ATRX 1 GO:2000508 regulation of dendritic cell chemotaxis 1/504 12/18722 0.279325576635374 0.51424308012191 GAS6 1 GO:2000628 regulation of miRNA metabolic process 1/504 12/18722 0.279325576635374 0.51424308012191 KCNQ1OT1 1 GO:0002700 regulation of production of molecular mediator of immune response 6/504 164/18722 0.280774477793172 0.516687917144799 SPON2/TGFB2/CD81/IL1R1/B2M/XBP1 6 GO:0007618 mating 2/504 39/18722 0.282825300708551 0.519343579685277 EDNRB/PTEN 2 GO:0042417 dopamine metabolic process 2/504 39/18722 0.282825300708551 0.519343579685277 TGFB2/MAOA 2 GO:0043267 negative regulation of potassium ion transport 2/504 39/18722 0.282825300708551 0.519343579685277 CAV1/PTEN 2 GO:0045823 positive regulation of heart contraction 2/504 39/18722 0.282825300708551 0.519343579685277 TPM1/TGFB2 2 GO:0045923 positive regulation of fatty acid metabolic process 2/504 39/18722 0.282825300708551 0.519343579685277 LPGAT1/ELOVL5 2 GO:0019218 regulation of steroid metabolic process 4/504 100/18722 0.283001397672981 0.519443716605089 IGFBP7/AGTR1/EGR1/TSPO 4 GO:0050810 regulation of steroid biosynthetic process 3/504 69/18722 0.284188157228314 0.521398023115752 IGFBP7/EGR1/TSPO 3 GO:0006576 cellular biogenic amine metabolic process 4/504 101/18722 0.289032638582899 0.528920195990696 NNMT/HAND2/TGFB2/MAOA 4 GO:0042102 positive regulation of T cell proliferation 4/504 101/18722 0.289032638582899 0.528920195990696 IGFBP2/CD81/IL6ST/IGF2 4 GO:0048024 regulation of mRNA splicing, via spliceosome 4/504 101/18722 0.289032638582899 0.528920195990696 MBNL2/MBNL1/DDX17/RBFOX2 4 GO:0042113 B cell activation 11/504 334/18722 0.290213378159316 0.528920195990696 LGALS1/MEF2C/CD81/ITGB1/KLF6/ZFP36L1/NOTCH2/XBP1/PIK3R1/NBN/AHR 11 GO:0070830 bicellular tight junction assembly 3/504 70/18722 0.291554274458033 0.528920195990696 MTDH/TJP1/ROCK2 3 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 8/504 233/18722 0.292170896848083 0.528920195990696 AKAP12/EDNRA/FLNA/ADCY3/RAMP1/LPAR1/ATP2B4/AKAP13 8 GO:0014037 Schwann cell differentiation 2/504 40/18722 0.292856116567701 0.528920195990696 LAMA2/LAMB2 2 GO:0031111 negative regulation of microtubule polymerization or depolymerization 2/504 40/18722 0.292856116567701 0.528920195990696 MAP1B/TAOK1 2 GO:0045022 early endosome to late endosome transport 2/504 40/18722 0.292856116567701 0.528920195990696 FLNA/MSN 2 GO:0045429 positive regulation of nitric oxide biosynthetic process 2/504 40/18722 0.292856116567701 0.528920195990696 DDAH2/PKD2 2 GO:0045740 positive regulation of DNA replication 2/504 40/18722 0.292856116567701 0.528920195990696 JUN/ATRX 2 GO:0055069 zinc ion homeostasis 2/504 40/18722 0.292856116567701 0.528920195990696 MT1E/SLC39A6 2 GO:0071276 cellular response to cadmium ion 2/504 40/18722 0.292856116567701 0.528920195990696 MT1E/JUN 2 GO:0097352 autophagosome maturation 2/504 40/18722 0.292856116567701 0.528920195990696 VMP1/MAP1LC3A 2 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 2/504 40/18722 0.292856116567701 0.528920195990696 PKD2/CALM2 2 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 2/504 40/18722 0.292856116567701 0.528920195990696 MDK/ETS1 2 GO:0001508 action potential 5/504 134/18722 0.29362062992509 0.528920195990696 GJC1/FLNA/SLMAP/SLC8A1/CAV1 5 GO:0072522 purine-containing compound biosynthetic process 7/504 200/18722 0.293979311168899 0.528920195990696 GUCY1A2/ADCY3/PAPSS2/TMSB4X/ELOVL5/STAT3/ACLY 7 GO:0099003 vesicle-mediated transport in synapse 7/504 200/18722 0.293979311168899 0.528920195990696 ACTB/PREPL/ITSN1/STON1/CTBP2/PTEN/ACTG1 7 GO:1904063 negative regulation of cation transmembrane transport 4/504 102/18722 0.295081604458267 0.528920195990696 CAV1/PKD2/CALM2/PTEN 4 GO:0006473 protein acetylation 7/504 201/18722 0.2982373240986 0.528920195990696 MYOCD/FOXO1/SOX4/CLOCK/TAOK1/KMT2A/EPC1 7 GO:0001778 plasma membrane repair 1/504 13/18722 0.29873871984092 0.528920195990696 MYH9 1 GO:0002087 regulation of respiratory gaseous exchange by nervous system process 1/504 13/18722 0.29873871984092 0.528920195990696 GLS 1 GO:0003222 ventricular trabecula myocardium morphogenesis 1/504 13/18722 0.29873871984092 0.528920195990696 TGFB2 1 GO:0005513 detection of calcium ion 1/504 13/18722 0.29873871984092 0.528920195990696 CALM2 1 GO:0006995 cellular response to nitrogen starvation 1/504 13/18722 0.29873871984092 0.528920195990696 MAP1LC3A 1 GO:0007494 midgut development 1/504 13/18722 0.29873871984092 0.528920195990696 EDNRB 1 GO:0007512 adult heart development 1/504 13/18722 0.29873871984092 0.528920195990696 HAND2 1 GO:0009143 nucleoside triphosphate catabolic process 1/504 13/18722 0.29873871984092 0.528920195990696 ENPP1 1 GO:0010755 regulation of plasminogen activation 1/504 13/18722 0.29873871984092 0.528920195990696 THBS1 1 GO:0010958 regulation of amino acid import across plasma membrane 1/504 13/18722 0.29873871984092 0.528920195990696 ITGB1 1 GO:0014842 regulation of skeletal muscle satellite cell proliferation 1/504 13/18722 0.29873871984092 0.528920195990696 STAT3 1 GO:0019336 phenol-containing compound catabolic process 1/504 13/18722 0.29873871984092 0.528920195990696 MAOA 1 GO:0021554 optic nerve development 1/504 13/18722 0.29873871984092 0.528920195990696 EXT1 1 GO:0021681 cerebellar granular layer development 1/504 13/18722 0.29873871984092 0.528920195990696 MDK 1 GO:0021859 pyramidal neuron differentiation 1/504 13/18722 0.29873871984092 0.528920195990696 ZMIZ1 1 GO:0030497 fatty acid elongation 1/504 13/18722 0.29873871984092 0.528920195990696 ELOVL5 1 GO:0031053 primary miRNA processing 1/504 13/18722 0.29873871984092 0.528920195990696 STAT3 1 GO:0031272 regulation of pseudopodium assembly 1/504 13/18722 0.29873871984092 0.528920195990696 CDC42EP3 1 GO:0031274 positive regulation of pseudopodium assembly 1/504 13/18722 0.29873871984092 0.528920195990696 CDC42EP3 1 GO:0032352 positive regulation of hormone metabolic process 1/504 13/18722 0.29873871984092 0.528920195990696 EGR1 1 GO:0032429 regulation of phospholipase A2 activity 1/504 13/18722 0.29873871984092 0.528920195990696 AGTR1 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/504 13/18722 0.29873871984092 0.528920195990696 ATRX 1 GO:0034135 regulation of toll-like receptor 2 signaling pathway 1/504 13/18722 0.29873871984092 0.528920195990696 PJA2 1 GO:0035745 T-helper 2 cell cytokine production 1/504 13/18722 0.29873871984092 0.528920195990696 CD81 1 GO:0036302 atrioventricular canal development 1/504 13/18722 0.29873871984092 0.528920195990696 TBX2 1 GO:0042492 gamma-delta T cell differentiation 1/504 13/18722 0.29873871984092 0.528920195990696 SOX4 1 GO:0042761 very long-chain fatty acid biosynthetic process 1/504 13/18722 0.29873871984092 0.528920195990696 ELOVL5 1 GO:0042769 DNA damage response, detection of DNA damage 1/504 13/18722 0.29873871984092 0.528920195990696 SOX4 1 GO:0043562 cellular response to nitrogen levels 1/504 13/18722 0.29873871984092 0.528920195990696 MAP1LC3A 1 GO:0043970 histone H3-K9 acetylation 1/504 13/18722 0.29873871984092 0.528920195990696 KMT2A 1 GO:0046642 negative regulation of alpha-beta T cell proliferation 1/504 13/18722 0.29873871984092 0.528920195990696 TWSG1 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/504 13/18722 0.29873871984092 0.528920195990696 HGF 1 GO:0048070 regulation of developmental pigmentation 1/504 13/18722 0.29873871984092 0.528920195990696 ZEB2 1 GO:0048711 positive regulation of astrocyte differentiation 1/504 13/18722 0.29873871984092 0.528920195990696 IL6ST 1 GO:0048820 hair follicle maturation 1/504 13/18722 0.29873871984092 0.528920195990696 TGFB2 1 GO:0051481 negative regulation of cytosolic calcium ion concentration 1/504 13/18722 0.29873871984092 0.528920195990696 SLC8A1 1 GO:0055062 phosphate ion homeostasis 1/504 13/18722 0.29873871984092 0.528920195990696 ENPP1 1 GO:0060347 heart trabecula formation 1/504 13/18722 0.29873871984092 0.528920195990696 ADAMTS1 1 GO:0060707 trophoblast giant cell differentiation 1/504 13/18722 0.29873871984092 0.528920195990696 NR2F2 1 GO:0061000 negative regulation of dendritic spine development 1/504 13/18722 0.29873871984092 0.528920195990696 PTEN 1 GO:0061469 regulation of type B pancreatic cell proliferation 1/504 13/18722 0.29873871984092 0.528920195990696 NR4A1 1 GO:0061744 motor behavior 1/504 13/18722 0.29873871984092 0.528920195990696 EXT1 1 GO:0070486 leukocyte aggregation 1/504 13/18722 0.29873871984092 0.528920195990696 MSN 1 GO:0071696 ectodermal placode development 1/504 13/18722 0.29873871984092 0.528920195990696 TBX2 1 GO:0072506 trivalent inorganic anion homeostasis 1/504 13/18722 0.29873871984092 0.528920195990696 ENPP1 1 GO:0072710 response to hydroxyurea 1/504 13/18722 0.29873871984092 0.528920195990696 ATRX 1 GO:0090042 tubulin deacetylation 1/504 13/18722 0.29873871984092 0.528920195990696 FLNA 1 GO:0098814 spontaneous synaptic transmission 1/504 13/18722 0.29873871984092 0.528920195990696 ITGB1 1 GO:0098840 protein transport along microtubule 1/504 13/18722 0.29873871984092 0.528920195990696 HSPB1 1 GO:0099118 microtubule-based protein transport 1/504 13/18722 0.29873871984092 0.528920195990696 HSPB1 1 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/504 13/18722 0.29873871984092 0.528920195990696 ATP2B4 1 GO:0120305 regulation of pigmentation 1/504 13/18722 0.29873871984092 0.528920195990696 ZEB2 1 GO:1900121 negative regulation of receptor binding 1/504 13/18722 0.29873871984092 0.528920195990696 B2M 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/504 13/18722 0.29873871984092 0.528920195990696 PLXND1 1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 1/504 13/18722 0.29873871984092 0.528920195990696 TMSB4X 1 GO:1903651 positive regulation of cytoplasmic transport 1/504 13/18722 0.29873871984092 0.528920195990696 MSN 1 GO:1903789 regulation of amino acid transmembrane transport 1/504 13/18722 0.29873871984092 0.528920195990696 ITGB1 1 GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/504 13/18722 0.29873871984092 0.528920195990696 TOMM7 1 GO:1905203 regulation of connective tissue replacement 1/504 13/18722 0.29873871984092 0.528920195990696 ROCK2 1 GO:1905244 regulation of modification of synaptic structure 1/504 13/18722 0.29873871984092 0.528920195990696 ITSN1 1 GO:1905907 negative regulation of amyloid fibril formation 1/504 13/18722 0.29873871984092 0.528920195990696 CRYAB 1 GO:1905939 regulation of gonad development 1/504 13/18722 0.29873871984092 0.528920195990696 CITED2 1 GO:2000551 regulation of T-helper 2 cell cytokine production 1/504 13/18722 0.29873871984092 0.528920195990696 CD81 1 GO:0008344 adult locomotory behavior 3/504 71/18722 0.298933366093501 0.528920195990696 CCND2/EPS8/HIPK2 3 GO:0072078 nephron tubule morphogenesis 3/504 71/18722 0.298933366093501 0.528920195990696 GPC3/PKD2/PBX1 3 GO:0099173 postsynapse organization 6/504 168/18722 0.299403352645389 0.529313415744206 FARP1/PDLIM5/ACTB/ACTN1/PTEN/ACTG1 6 GO:2000241 regulation of reproductive process 6/504 168/18722 0.299403352645389 0.529313415744206 PDE3A/TIMP1/EDNRB/MYH9/CITED2/PRKAR1A 6 GO:0051222 positive regulation of protein transport 10/504 303/18722 0.300629945140008 0.531262099083232 CAMK2N1/FLNA/GAS6/TGFB2/CD81/SOX4/ADAM9/PIK3R1/STOM/TOMM7 10 GO:0002027 regulation of heart rate 4/504 103/18722 0.301146518197968 0.53195496992969 TPM1/SLC8A1/CAV1/CALM2 4 GO:0019722 calcium-mediated signaling 7/504 202/18722 0.30250857584029 0.53279276297512 AGTR1/LMCD1/SLC8A1/EDNRB/DYRK2/ATP2B4/CALM2 7 GO:0031062 positive regulation of histone methylation 2/504 41/18722 0.302867685763297 0.53279276297512 KMT2E/KMT2A 2 GO:0042307 positive regulation of protein import into nucleus 2/504 41/18722 0.302867685763297 0.53279276297512 FLNA/PIK3R1 2 GO:0048634 regulation of muscle organ development 2/504 41/18722 0.302867685763297 0.53279276297512 MEF2C/IGF2 2 GO:0050856 regulation of T cell receptor signaling pathway 2/504 41/18722 0.302867685763297 0.53279276297512 THY1/CD81 2 GO:0060612 adipose tissue development 2/504 41/18722 0.302867685763297 0.53279276297512 ARID5B/XBP1 2 GO:0070296 sarcoplasmic reticulum calcium ion transport 2/504 41/18722 0.302867685763297 0.53279276297512 SLC8A1/CALM2 2 GO:1900371 regulation of purine nucleotide biosynthetic process 2/504 41/18722 0.302867685763297 0.53279276297512 TMSB4X/STAT3 2 GO:1903524 positive regulation of blood circulation 2/504 41/18722 0.302867685763297 0.53279276297512 TPM1/TGFB2 2 GO:1904407 positive regulation of nitric oxide metabolic process 2/504 41/18722 0.302867685763297 0.53279276297512 DDAH2/PKD2 2 GO:0018209 peptidyl-serine modification 11/504 338/18722 0.303294345124149 0.533323759965222 DCN/HGF/GAS6/BGN/DYRK2/ATP2B4/CAV1/HIPK2/ROCK2/PTEN/AKT3 11 GO:0098876 vesicle-mediated transport to the plasma membrane 5/504 136/18722 0.304122069236335 0.534559276777811 EHD2/SPTBN1/PREPL/ARL3/MACF1 5 GO:0042246 tissue regeneration 3/504 72/18722 0.306322383145892 0.538205404269078 APOD/CD81/MDK 3 GO:0019318 hexose metabolic process 8/504 237/18722 0.307945401491377 0.540730158857221 IGFBP4/NNMT/APOD/ENPP1/DYRK2/IGF2/ATF3/MAN2A1 8 GO:0007259 receptor signaling pathway via JAK-STAT 6/504 170/18722 0.308805640149339 0.540730158857221 IL6ST/CAV1/PKD2/JAK1/STAT3/STAT2 6 GO:0034754 cellular hormone metabolic process 5/504 137/18722 0.309394195837558 0.540730158857221 RBP1/PDGFRA/EGR1/TSPO/DHRS3 5 GO:0045471 response to ethanol 5/504 137/18722 0.309394195837558 0.540730158857221 SPARC/EPS8/EIF4EBP1/STAT3/PTEN 5 GO:0050671 positive regulation of lymphocyte proliferation 5/504 137/18722 0.309394195837558 0.540730158857221 IGFBP2/MEF2C/CD81/IL6ST/IGF2 5 GO:0050684 regulation of mRNA processing 5/504 137/18722 0.309394195837558 0.540730158857221 MBNL2/ZFP36L1/MBNL1/DDX17/RBFOX2 5 GO:0051259 protein complex oligomerization 8/504 238/18722 0.311917826136238 0.540730158857221 COL1A2/UGDH/ATL3/B2M/KCTD12/PKD2/GLS/ISG15 8 GO:0000266 mitochondrial fission 2/504 42/18722 0.312853785239605 0.540730158857221 DCN/STAT2 2 GO:0000413 protein peptidyl-prolyl isomerization 2/504 42/18722 0.312853785239605 0.540730158857221 FKBP10/FKBP14 2 GO:0007212 dopamine receptor signaling pathway 2/504 42/18722 0.312853785239605 0.540730158857221 FLNA/CAV2 2 GO:0010591 regulation of lamellipodium assembly 2/504 42/18722 0.312853785239605 0.540730158857221 NCKAP1/PIK3R1 2 GO:0010677 negative regulation of cellular carbohydrate metabolic process 2/504 42/18722 0.312853785239605 0.540730158857221 ENPP1/STAT3 2 GO:0010939 regulation of necrotic cell death 2/504 42/18722 0.312853785239605 0.540730158857221 CAV1/TSPO 2 GO:0016601 Rac protein signal transduction 2/504 42/18722 0.312853785239605 0.540730158857221 EPS8/NCKAP1 2 GO:0021795 cerebral cortex cell migration 2/504 42/18722 0.312853785239605 0.540730158857221 LAMB1/ZMIZ1 2 GO:0021879 forebrain neuron differentiation 2/504 42/18722 0.312853785239605 0.540730158857221 B2M/ZMIZ1 2 GO:0030808 regulation of nucleotide biosynthetic process 2/504 42/18722 0.312853785239605 0.540730158857221 TMSB4X/STAT3 2 GO:0030890 positive regulation of B cell proliferation 2/504 42/18722 0.312853785239605 0.540730158857221 MEF2C/CD81 2 GO:0032689 negative regulation of interferon-gamma production 2/504 42/18722 0.312853785239605 0.540730158857221 GAS6/AXL 2 GO:0042168 heme metabolic process 2/504 42/18722 0.312853785239605 0.540730158857221 TSPO/NFE2L1 2 GO:0045687 positive regulation of glial cell differentiation 2/504 42/18722 0.312853785239605 0.540730158857221 MDK/IL6ST 2 GO:0072595 maintenance of protein localization in organelle 2/504 42/18722 0.312853785239605 0.540730158857221 SYNE1/TSPO 2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 2/504 42/18722 0.312853785239605 0.540730158857221 THBS1/STARD13 2 GO:0090317 negative regulation of intracellular protein transport 2/504 42/18722 0.312853785239605 0.540730158857221 APOD/PKIG 2 GO:0046890 regulation of lipid biosynthetic process 6/504 171/18722 0.313525877972459 0.540730158857221 IGFBP7/EGR1/TSPO/LPGAT1/PDGFA/ELOVL5 6 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 3/504 73/18722 0.313718350572041 0.540730158857221 CAMK2N1/MAP4K4/RAB11FIP2 3 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 3/504 73/18722 0.313718350572041 0.540730158857221 ITGA1/HIP1/SOS1 3 GO:0072088 nephron epithelium morphogenesis 3/504 73/18722 0.313718350572041 0.540730158857221 GPC3/PKD2/PBX1 3 GO:0032946 positive regulation of mononuclear cell proliferation 5/504 138/18722 0.314679070815248 0.540730158857221 IGFBP2/MEF2C/CD81/IL6ST/IGF2 5 GO:0002467 germinal center formation 1/504 14/18722 0.317629931835157 0.540730158857221 MEF2C 1 GO:0002475 antigen processing and presentation via MHC class Ib 1/504 14/18722 0.317629931835157 0.540730158857221 B2M 1 GO:0002756 MyD88-independent toll-like receptor signaling pathway 1/504 14/18722 0.317629931835157 0.540730158857221 RAB11FIP2 1 GO:0006521 regulation of cellular amino acid metabolic process 1/504 14/18722 0.317629931835157 0.540730158857221 ATP2B4 1 GO:0006596 polyamine biosynthetic process 1/504 14/18722 0.317629931835157 0.540730158857221 NNMT 1 GO:0007100 mitotic centrosome separation 1/504 14/18722 0.317629931835157 0.540730158857221 MAP9 1 GO:0009214 cyclic nucleotide catabolic process 1/504 14/18722 0.317629931835157 0.540730158857221 PDE8B 1 GO:0010421 hydrogen peroxide-mediated programmed cell death 1/504 14/18722 0.317629931835157 0.540730158857221 HGF 1 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1/504 14/18722 0.317629931835157 0.540730158857221 ACTN4 1 GO:0010872 regulation of cholesterol esterification 1/504 14/18722 0.317629931835157 0.540730158857221 AGTR1 1 GO:0014874 response to stimulus involved in regulation of muscle adaptation 1/504 14/18722 0.317629931835157 0.540730158857221 FBXO32 1 GO:0031650 regulation of heat generation 1/504 14/18722 0.317629931835157 0.540730158857221 EDNRB 1 GO:0032966 negative regulation of collagen biosynthetic process 1/504 14/18722 0.317629931835157 0.540730158857221 EMILIN1 1 GO:0033212 iron import into cell 1/504 14/18722 0.317629931835157 0.540730158857221 CYBRD1 1 GO:0034111 negative regulation of homotypic cell-cell adhesion 1/504 14/18722 0.317629931835157 0.540730158857221 PRKG1 1 GO:0035563 positive regulation of chromatin binding 1/504 14/18722 0.317629931835157 0.540730158857221 CTBP2 1 GO:0035810 positive regulation of urine volume 1/504 14/18722 0.317629931835157 0.540730158857221 EDNRB 1 GO:0035815 positive regulation of renal sodium excretion 1/504 14/18722 0.317629931835157 0.540730158857221 EDNRB 1 GO:0042415 norepinephrine metabolic process 1/504 14/18722 0.317629931835157 0.540730158857221 HAND2 1 GO:0043455 regulation of secondary metabolic process 1/504 14/18722 0.317629931835157 0.540730158857221 ZEB2 1 GO:0043650 dicarboxylic acid biosynthetic process 1/504 14/18722 0.317629931835157 0.540730158857221 GLS 1 GO:0043922 negative regulation by host of viral transcription 1/504 14/18722 0.317629931835157 0.540730158857221 JUN 1 GO:0043951 negative regulation of cAMP-mediated signaling 1/504 14/18722 0.317629931835157 0.540730158857221 PDE3A 1 GO:0044154 histone H3-K14 acetylation 1/504 14/18722 0.317629931835157 0.540730158857221 KMT2A 1 GO:0045579 positive regulation of B cell differentiation 1/504 14/18722 0.317629931835157 0.540730158857221 XBP1 1 GO:0045820 negative regulation of glycolytic process 1/504 14/18722 0.317629931835157 0.540730158857221 STAT3 1 GO:0048021 regulation of melanin biosynthetic process 1/504 14/18722 0.317629931835157 0.540730158857221 ZEB2 1 GO:0048368 lateral mesoderm development 1/504 14/18722 0.317629931835157 0.540730158857221 CITED2 1 GO:0048681 negative regulation of axon regeneration 1/504 14/18722 0.317629931835157 0.540730158857221 PTEN 1 GO:0051917 regulation of fibrinolysis 1/504 14/18722 0.317629931835157 0.540730158857221 THBS1 1 GO:0051984 positive regulation of chromosome segregation 1/504 14/18722 0.317629931835157 0.540730158857221 SMC6 1 GO:0060354 negative regulation of cell adhesion molecule production 1/504 14/18722 0.317629931835157 0.540730158857221 MYOCD 1 GO:0060576 intestinal epithelial cell development 1/504 14/18722 0.317629931835157 0.540730158857221 IL6ST 1 GO:0060841 venous blood vessel development 1/504 14/18722 0.317629931835157 0.540730158857221 BMPR2 1 GO:0061043 regulation of vascular wound healing 1/504 14/18722 0.317629931835157 0.540730158857221 XBP1 1 GO:0070307 lens fiber cell development 1/504 14/18722 0.317629931835157 0.540730158857221 VIM 1 GO:0071415 cellular response to purine-containing compound 1/504 14/18722 0.317629931835157 0.540730158857221 SLC8A1 1 GO:0071481 cellular response to X-ray 1/504 14/18722 0.317629931835157 0.540730158857221 CCND2 1 GO:0072350 tricarboxylic acid metabolic process 1/504 14/18722 0.317629931835157 0.540730158857221 ACLY 1 GO:0072498 embryonic skeletal joint development 1/504 14/18722 0.317629931835157 0.540730158857221 EXT1 1 GO:0072540 T-helper 17 cell lineage commitment 1/504 14/18722 0.317629931835157 0.540730158857221 STAT3 1 GO:0097091 synaptic vesicle clustering 1/504 14/18722 0.317629931835157 0.540730158857221 PTEN 1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 1/504 14/18722 0.317629931835157 0.540730158857221 ACTN4 1 GO:1900037 regulation of cellular response to hypoxia 1/504 14/18722 0.317629931835157 0.540730158857221 ROCK2 1 GO:1900376 regulation of secondary metabolite biosynthetic process 1/504 14/18722 0.317629931835157 0.540730158857221 ZEB2 1 GO:1901722 regulation of cell proliferation involved in kidney development 1/504 14/18722 0.317629931835157 0.540730158857221 EGR1 1 GO:1904294 positive regulation of ERAD pathway 1/504 14/18722 0.317629931835157 0.540730158857221 CAV1 1 GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/504 14/18722 0.317629931835157 0.540730158857221 TOMM7 1 GO:1905208 negative regulation of cardiocyte differentiation 1/504 14/18722 0.317629931835157 0.540730158857221 SOX6 1 GO:0042770 signal transduction in response to DNA damage 6/504 172/18722 0.318257760556956 0.541583198271555 SOX4/HIPK2/CLOCK/ATRX/TAOK1/NBN 6 GO:0035821 modulation of process of other organism 4/504 106/18722 0.319419505040212 0.542911513538913 IFI27/CAV2/JUN/STOM 4 GO:0071887 leukocyte apoptotic process 4/504 106/18722 0.319419505040212 0.542911513538913 GAS6/AXL/MEF2C/PTEN 4 GO:2000278 regulation of DNA biosynthetic process 4/504 106/18722 0.319419505040212 0.542911513538913 PDGFRB/PARM1/HGF/BMPR2 4 GO:0051783 regulation of nuclear division 5/504 139/18722 0.319975562833768 0.543640389657532 PDGFRB/PDE3A/IGF2/CAV2/PRKAR1A 5 GO:0002437 inflammatory response to antigenic stimulus 3/504 74/18722 0.32111836766319 0.544499517866988 CD81/EXT1/NOTCH2 3 GO:0006801 superoxide metabolic process 3/504 74/18722 0.32111836766319 0.544499517866988 FBLN5/SH3PXD2A/SOD3 3 GO:0030968 endoplasmic reticulum unfolded protein response 3/504 74/18722 0.32111836766319 0.544499517866988 XBP1/ATF3/PIK3R1 3 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 3/504 74/18722 0.32111836766319 0.544499517866988 KANK2/NCOR2/CLOCK 3 GO:1903201 regulation of oxidative stress-induced cell death 3/504 74/18722 0.32111836766319 0.544499517866988 HGF/HSPB1/NCOA7 3 GO:0006874 cellular calcium ion homeostasis 14/504 448/18722 0.322195549764711 0.545633263366385 THY1/AGTR1/EDNRA/PDGFRA/LPAR1/SLC8A1/EDNRB/ATP2B4/CAV1/CAV2/PKD2/CALM2/HSP90B1/NPTN 14 GO:0036230 granulocyte activation 2/504 43/18722 0.322808539618587 0.545633263366385 PLA2G2A/KMT2E 2 GO:0045840 positive regulation of mitotic nuclear division 2/504 43/18722 0.322808539618587 0.545633263366385 PDGFRB/IGF2 2 GO:0045981 positive regulation of nucleotide metabolic process 2/504 43/18722 0.322808539618587 0.545633263366385 TMSB4X/STAT3 2 GO:0098927 vesicle-mediated transport between endosomal compartments 2/504 43/18722 0.322808539618587 0.545633263366385 FLNA/MSN 2 GO:0120178 steroid hormone biosynthetic process 2/504 43/18722 0.322808539618587 0.545633263366385 EGR1/TSPO 2 GO:1900544 positive regulation of purine nucleotide metabolic process 2/504 43/18722 0.322808539618587 0.545633263366385 TMSB4X/STAT3 2 GO:1904591 positive regulation of protein import 2/504 43/18722 0.322808539618587 0.545633263366385 FLNA/PIK3R1 2 GO:0006694 steroid biosynthetic process 6/504 173/18722 0.323000479035721 0.545741813728602 IGFBP7/EGR1/TSPO/CYB5R3/PBX1/ACLY 6 GO:0006813 potassium ion transport 8/504 241/18722 0.323896464889306 0.547039365403954 FXYD1/FHL1/FLNA/KCNK6/ITGB1/CAV1/PKD2/PTEN 8 GO:0050768 negative regulation of neurogenesis 5/504 140/18722 0.325282549853425 0.549148625117042 THY1/SEMA5A/B2M/TSPO/PTEN 5 GO:0006275 regulation of DNA replication 4/504 107/18722 0.325530884020938 0.549148625117042 ZBTB38/JUN/ATRX/NBN 4 GO:0021761 limbic system development 4/504 107/18722 0.325530884020938 0.549148625117042 MDK/ETS1/ATP2B4/PTEN 4 GO:1903320 regulation of protein modification by small protein conjugation or removal 8/504 242/18722 0.327908187120446 0.550953369063418 NXN/SOX4/CAV1/EGR1/TSPO/ISG15/PTEN/ZMIZ1 8 GO:0008088 axo-dendritic transport 3/504 75/18722 0.328519608302138 0.550953369063418 DST/HSPB1/ARMCX3 3 GO:0033077 T cell differentiation in thymus 3/504 75/18722 0.328519608302138 0.550953369063418 B2M/ZFP36L1/SOS1 3 GO:0045913 positive regulation of carbohydrate metabolic process 3/504 75/18722 0.328519608302138 0.550953369063418 NNMT/DYRK2/IGF2 3 GO:2001259 positive regulation of cation channel activity 3/504 75/18722 0.328519608302138 0.550953369063418 TMSB4X/PKD2/CALM2 3 GO:1903038 negative regulation of leukocyte cell-cell adhesion 5/504 141/18722 0.330598919616185 0.550953369063418 LRRC32/PAG1/TWSG1/MDK/PRKAR1A 5 GO:0002066 columnar/cuboidal epithelial cell development 2/504 44/18722 0.332726407054273 0.550953369063418 IL6ST/CLOCK 2 GO:0007528 neuromuscular junction development 2/504 44/18722 0.332726407054273 0.550953369063418 COL4A1/LAMB2 2 GO:0008542 visual learning 2/504 44/18722 0.332726407054273 0.550953369063418 ITGB1/NPTN 2 GO:0048806 genitalia development 2/504 44/18722 0.332726407054273 0.550953369063418 PDGFRA/AXL 2 GO:0051150 regulation of smooth muscle cell differentiation 2/504 44/18722 0.332726407054273 0.550953369063418 MYOCD/EFEMP2 2 GO:0060711 labyrinthine layer development 2/504 44/18722 0.332726407054273 0.550953369063418 WNT2/ZFP36L1 2 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 2/504 44/18722 0.332726407054273 0.550953369063418 CAV1/PJA2 2 GO:0097178 ruffle assembly 2/504 44/18722 0.332726407054273 0.550953369063418 EPS8/CAV1 2 GO:0006305 DNA alkylation 3/504 76/18722 0.335919321097084 0.550953369063418 KMT2E/ATRX/KMT2A 3 GO:0006306 DNA methylation 3/504 76/18722 0.335919321097084 0.550953369063418 KMT2E/ATRX/KMT2A 3 GO:0008652 cellular amino acid biosynthetic process 3/504 76/18722 0.335919321097084 0.550953369063418 ATP2B4/GLS/PLOD2 3 GO:0014823 response to activity 3/504 76/18722 0.335919321097084 0.550953369063418 RARRES2/COL4A2/PTEN 3 GO:0032720 negative regulation of tumor necrosis factor production 3/504 76/18722 0.335919321097084 0.550953369063418 GAS6/AXL/TSPO 3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 3/504 76/18722 0.335919321097084 0.550953369063418 DYRK2/HIPK2/IFI16 3 GO:0140115 export across plasma membrane 3/504 76/18722 0.335919321097084 0.550953369063418 FXYD1/SLC8A1/CALM2 3 GO:0097553 calcium ion transmembrane import into cytosol 5/504 142/18722 0.335923570110779 0.550953369063418 THY1/SLC8A1/ATP2B4/PKD2/CALM2 5 GO:0000722 telomere maintenance via recombination 1/504 15/18722 0.336013217828052 0.550953369063418 SMC6 1 GO:0001325 formation of extrachromosomal circular DNA 1/504 15/18722 0.336013217828052 0.550953369063418 NBN 1 GO:0002468 dendritic cell antigen processing and presentation 1/504 15/18722 0.336013217828052 0.550953369063418 THBS1 1 GO:0010273 detoxification of copper ion 1/504 15/18722 0.336013217828052 0.550953369063418 MT1E 1 GO:0010713 negative regulation of collagen metabolic process 1/504 15/18722 0.336013217828052 0.550953369063418 EMILIN1 1 GO:0010752 regulation of cGMP-mediated signaling 1/504 15/18722 0.336013217828052 0.550953369063418 THBS1 1 GO:0010940 positive regulation of necrotic cell death 1/504 15/18722 0.336013217828052 0.550953369063418 TSPO 1 GO:0014733 regulation of skeletal muscle adaptation 1/504 15/18722 0.336013217828052 0.550953369063418 IGFBP5 1 GO:0014841 skeletal muscle satellite cell proliferation 1/504 15/18722 0.336013217828052 0.550953369063418 STAT3 1 GO:0014857 regulation of skeletal muscle cell proliferation 1/504 15/18722 0.336013217828052 0.550953369063418 STAT3 1 GO:0015697 quaternary ammonium group transport 1/504 15/18722 0.336013217828052 0.550953369063418 SLC38A2 1 GO:0016114 terpenoid biosynthetic process 1/504 15/18722 0.336013217828052 0.550953369063418 RBP1 1 GO:0019511 peptidyl-proline hydroxylation 1/504 15/18722 0.336013217828052 0.550953369063418 CRTAP 1 GO:0023035 CD40 signaling pathway 1/504 15/18722 0.336013217828052 0.550953369063418 ITGB1 1 GO:0031269 pseudopodium assembly 1/504 15/18722 0.336013217828052 0.550953369063418 CDC42EP3 1 GO:0032328 alanine transport 1/504 15/18722 0.336013217828052 0.550953369063418 SLC38A2 1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 1/504 15/18722 0.336013217828052 0.550953369063418 KANK2 1 GO:0034384 high-density lipoprotein particle clearance 1/504 15/18722 0.336013217828052 0.550953369063418 LIPG 1 GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway 1/504 15/18722 0.336013217828052 0.550953369063418 CITED2 1 GO:0036124 histone H3-K9 trimethylation 1/504 15/18722 0.336013217828052 0.550953369063418 ATRX 1 GO:0042074 cell migration involved in gastrulation 1/504 15/18722 0.336013217828052 0.550953369063418 GPC3 1 GO:0043508 negative regulation of JUN kinase activity 1/504 15/18722 0.336013217828052 0.550953369063418 AIDA 1 GO:0045176 apical protein localization 1/504 15/18722 0.336013217828052 0.550953369063418 ACTB 1 GO:0045346 regulation of MHC class II biosynthetic process 1/504 15/18722 0.336013217828052 0.550953369063418 XBP1 1 GO:0048569 post-embryonic animal organ development 1/504 15/18722 0.336013217828052 0.550953369063418 FBN1 1 GO:0051290 protein heterotetramerization 1/504 15/18722 0.336013217828052 0.550953369063418 PKD2 1 GO:0051299 centrosome separation 1/504 15/18722 0.336013217828052 0.550953369063418 MAP9 1 GO:0051775 response to redox state 1/504 15/18722 0.336013217828052 0.550953369063418 CLOCK 1 GO:0051938 L-glutamate import 1/504 15/18722 0.336013217828052 0.550953369063418 ITGB1 1 GO:0055091 phospholipid homeostasis 1/504 15/18722 0.336013217828052 0.550953369063418 LIPG 1 GO:0060026 convergent extension 1/504 15/18722 0.336013217828052 0.550953369063418 PTK7 1 GO:0060049 regulation of protein glycosylation 1/504 15/18722 0.336013217828052 0.550953369063418 RAMP1 1 GO:0060253 negative regulation of glial cell proliferation 1/504 15/18722 0.336013217828052 0.550953369063418 TSPO 1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1/504 15/18722 0.336013217828052 0.550953369063418 GAS1 1 GO:0060766 negative regulation of androgen receptor signaling pathway 1/504 15/18722 0.336013217828052 0.550953369063418 NCOR2 1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum 1/504 15/18722 0.336013217828052 0.550953369063418 CD81 1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 1/504 15/18722 0.336013217828052 0.550953369063418 LMCD1 1 GO:0071871 response to epinephrine 1/504 15/18722 0.336013217828052 0.550953369063418 ATP2B4 1 GO:0080154 regulation of fertilization 1/504 15/18722 0.336013217828052 0.550953369063418 MYH9 1 GO:0090656 t-circle formation 1/504 15/18722 0.336013217828052 0.550953369063418 NBN 1 GO:0090737 telomere maintenance via telomere trimming 1/504 15/18722 0.336013217828052 0.550953369063418 NBN 1 GO:0097468 programmed cell death in response to reactive oxygen species 1/504 15/18722 0.336013217828052 0.550953369063418 HGF 1 GO:0098712 L-glutamate import across plasma membrane 1/504 15/18722 0.336013217828052 0.550953369063418 ITGB1 1 GO:0106058 positive regulation of calcineurin-mediated signaling 1/504 15/18722 0.336013217828052 0.550953369063418 LMCD1 1 GO:0110156 methylguanosine-cap decapping 1/504 15/18722 0.336013217828052 0.550953369063418 ZFP36 1 GO:1900029 positive regulation of ruffle assembly 1/504 15/18722 0.336013217828052 0.550953369063418 EPS8 1 GO:1901741 positive regulation of myoblast fusion 1/504 15/18722 0.336013217828052 0.550953369063418 EHD2 1 GO:1902018 negative regulation of cilium assembly 1/504 15/18722 0.336013217828052 0.550953369063418 MAP4 1 GO:1990169 stress response to copper ion 1/504 15/18722 0.336013217828052 0.550953369063418 MT1E 1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway 1/504 15/18722 0.336013217828052 0.550953369063418 GPC3 1 GO:2000402 negative regulation of lymphocyte migration 1/504 15/18722 0.336013217828052 0.550953369063418 APOD 1 GO:0032410 negative regulation of transporter activity 4/504 109/18722 0.337774213906374 0.553416110437859 CAV1/PKD2/CALM2/PTEN 4 GO:0034766 negative regulation of ion transmembrane transport 4/504 109/18722 0.337774213906374 0.553416110437859 CAV1/PKD2/CALM2/PTEN 4 GO:0006814 sodium ion transport 8/504 245/18722 0.339993130875455 0.556624769437095 FXYD1/SLMAP/SLC8A1/ATP2B4/SLC38A2/ACTN4/PKD2/STOM 8 GO:0017148 negative regulation of translation 8/504 245/18722 0.339993130875455 0.556624769437095 IGFBP5/ZFP36L1/EIF4EBP1/ZFP36/ROCK2/STAT3/TNRC6B/EIF4EBP2 8 GO:0038061 NIK/NF-kappaB signaling 5/504 143/18722 0.341255410017398 0.558263540200744 UACA/TMSB4X/LIMS1/ACTN4/HDAC7 5 GO:0070555 response to interleukin-1 5/504 143/18722 0.341255410017398 0.558263540200744 AKAP12/TFPI/IL1R1/ETS1/EGR1 5 GO:0050807 regulation of synapse organization 7/504 211/18722 0.341444043590892 0.558358361371558 SPARC/TUBA1A/FARP1/PDLIM5/MEF2C/ITSN1/PTEN 7 GO:0021700 developmental maturation 9/504 280/18722 0.341808742630022 0.558740917084194 MAP1B/PDE3A/AXL/TGFB2/MMP2/NFIA/EXT1/EDNRB/PTEN 9 GO:0071466 cellular response to xenobiotic stimulus 6/504 177/18722 0.342063684092352 0.558755363963587 GAS6/RAP2A/MEF2C/PPP1R12A/GSTM3/AHR 6 GO:0030850 prostate gland development 2/504 45/18722 0.342602165594336 0.558755363963587 CRIP1/PTEN 2 GO:0035305 negative regulation of dephosphorylation 2/504 45/18722 0.342602165594336 0.558755363963587 TGFB2/ROCK2 2 GO:0035384 thioester biosynthetic process 2/504 45/18722 0.342602165594336 0.558755363963587 ELOVL5/ACLY 2 GO:0071616 acyl-CoA biosynthetic process 2/504 45/18722 0.342602165594336 0.558755363963587 ELOVL5/ACLY 2 GO:1901985 positive regulation of protein acetylation 2/504 45/18722 0.342602165594336 0.558755363963587 SOX4/TAOK1 2 GO:0021675 nerve development 3/504 77/18722 0.343314829400065 0.559277264973876 SULF2/EXT1/CITED2 3 GO:0031016 pancreas development 3/504 77/18722 0.343314829400065 0.559277264973876 SOX4/IGF2/CLOCK 3 GO:0055117 regulation of cardiac muscle contraction 3/504 77/18722 0.343314829400065 0.559277264973876 SLC8A1/CAV1/CALM2 3 GO:0002698 negative regulation of immune effector process 4/504 110/18722 0.343902918731355 0.559382250376505 TGFB2/A2M/SERPING1/AHR 4 GO:0009408 response to heat 4/504 110/18722 0.343902918731355 0.559382250376505 IGFBP7/THBS1/TGFB1I1/HSPA2 4 GO:0032611 interleukin-1 beta production 4/504 110/18722 0.343902918731355 0.559382250376505 EGR1/IFI16/HSPB1/STAT3 4 GO:0032651 regulation of interleukin-1 beta production 4/504 110/18722 0.343902918731355 0.559382250376505 EGR1/IFI16/HSPB1/STAT3 4 GO:0007249 I-kappaB kinase/NF-kappaB signaling 9/504 281/18722 0.345592934142576 0.561747449692096 FLNA/LGALS1/LPAR1/MTDH/HSPB1/ZMYND11/S100A4/ROCK2/AKAP13 9 GO:0043523 regulation of neuron apoptotic process 7/504 212/18722 0.345813922297552 0.561747449692096 ITGA1/AXL/TGFB2/MEF2C/MDK/HIPK2/JUN 7 GO:0007612 learning 5/504 144/18722 0.346593359132288 0.561747449692096 ADCY3/ATXN1/ITGB1/JUN/NPTN 5 GO:0031644 regulation of nervous system process 5/504 144/18722 0.346593359132288 0.561747449692096 HGF/EDNRB/ROCK2/PTEN/DLGAP4 5 GO:0033135 regulation of peptidyl-serine phosphorylation 5/504 144/18722 0.346593359132288 0.561747449692096 HGF/GAS6/ATP2B4/CAV1/PTEN 5 GO:0006109 regulation of carbohydrate metabolic process 6/504 178/18722 0.3468486029789 0.561747449692096 IGFBP4/NNMT/ENPP1/DYRK2/IGF2/STAT3 6 GO:0008306 associative learning 3/504 78/18722 0.350703531217528 0.561747449692096 ADCY3/ITGB1/NPTN 3 GO:0009064 glutamine family amino acid metabolic process 3/504 78/18722 0.350703531217528 0.561747449692096 ATP2B4/DDAH2/GLS 3 GO:0032371 regulation of sterol transport 3/504 78/18722 0.350703531217528 0.561747449692096 LIPG/CAV1/TSPO 3 GO:0032374 regulation of cholesterol transport 3/504 78/18722 0.350703531217528 0.561747449692096 LIPG/CAV1/TSPO 3 GO:1901616 organic hydroxy compound catabolic process 3/504 78/18722 0.350703531217528 0.561747449692096 INPP4B/MAOA/PTEN 3 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 3/504 78/18722 0.350703531217528 0.561747449692096 GAS6/AXL/TSPO 3 GO:0051961 negative regulation of nervous system development 5/504 145/18722 0.351936348772465 0.561747449692096 THY1/SEMA5A/B2M/TSPO/PTEN 5 GO:0061351 neural precursor cell proliferation 5/504 145/18722 0.351936348772465 0.561747449692096 WNT2/FLNA/LIMS2/ZNF503/MDK 5 GO:0007019 microtubule depolymerization 2/504 46/18722 0.352430900031872 0.561747449692096 MAP1B/TAOK1 2 GO:0010830 regulation of myotube differentiation 2/504 46/18722 0.352430900031872 0.561747449692096 MYOCD/XBP1 2 GO:0031018 endocrine pancreas development 2/504 46/18722 0.352430900031872 0.561747449692096 SOX4/CLOCK 2 GO:0032924 activin receptor signaling pathway 2/504 46/18722 0.352430900031872 0.561747449692096 CITED2/BMPR2 2 GO:0044818 mitotic G2/M transition checkpoint 2/504 46/18722 0.352430900031872 0.561747449692096 TAOK1/NBN 2 GO:0055010 ventricular cardiac muscle tissue morphogenesis 2/504 46/18722 0.352430900031872 0.561747449692096 TPM1/TGFB2 2 GO:0061462 protein localization to lysosome 2/504 46/18722 0.352430900031872 0.561747449692096 CD81/ROCK2 2 GO:0090329 regulation of DNA-dependent DNA replication 2/504 46/18722 0.352430900031872 0.561747449692096 ATRX/NBN 2 GO:2000107 negative regulation of leukocyte apoptotic process 2/504 46/18722 0.352430900031872 0.561747449692096 GAS6/AXL 2 GO:0001977 renal system process involved in regulation of blood volume 1/504 16/18722 0.353902207950181 0.561747449692096 GAS6 1 GO:0002399 MHC class II protein complex assembly 1/504 16/18722 0.353902207950181 0.561747449692096 B2M 1 GO:0002503 peptide antigen assembly with MHC class II protein complex 1/504 16/18722 0.353902207950181 0.561747449692096 B2M 1 GO:0002827 positive regulation of T-helper 1 type immune response 1/504 16/18722 0.353902207950181 0.561747449692096 IL1R1 1 GO:0002830 positive regulation of type 2 immune response 1/504 16/18722 0.353902207950181 0.561747449692096 CD81 1 GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 1/504 16/18722 0.353902207950181 0.561747449692096 TGFB2 1 GO:0006857 oligopeptide transport 1/504 16/18722 0.353902207950181 0.561747449692096 MGST1 1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1/504 16/18722 0.353902207950181 0.561747449692096 HIPK2 1 GO:0007635 chemosensory behavior 1/504 16/18722 0.353902207950181 0.561747449692096 ADCY3 1 GO:0009642 response to light intensity 1/504 16/18722 0.353902207950181 0.561747449692096 EXT1 1 GO:0014819 regulation of skeletal muscle contraction 1/504 16/18722 0.353902207950181 0.561747449692096 NR4A1 1 GO:0030033 microvillus assembly 1/504 16/18722 0.353902207950181 0.561747449692096 RAP2A 1 GO:0030540 female genitalia development 1/504 16/18722 0.353902207950181 0.561747449692096 AXL 1 GO:0031268 pseudopodium organization 1/504 16/18722 0.353902207950181 0.561747449692096 CDC42EP3 1 GO:0034116 positive regulation of heterotypic cell-cell adhesion 1/504 16/18722 0.353902207950181 0.561747449692096 THY1 1 GO:0034138 toll-like receptor 3 signaling pathway 1/504 16/18722 0.353902207950181 0.561747449692096 CAV1 1 GO:0034375 high-density lipoprotein particle remodeling 1/504 16/18722 0.353902207950181 0.561747449692096 LIPG 1 GO:0043923 positive regulation by host of viral transcription 1/504 16/18722 0.353902207950181 0.561747449692096 JUN 1 GO:0044065 regulation of respiratory system process 1/504 16/18722 0.353902207950181 0.561747449692096 GLS 1 GO:0045342 MHC class II biosynthetic process 1/504 16/18722 0.353902207950181 0.561747449692096 XBP1 1 GO:0045722 positive regulation of gluconeogenesis 1/504 16/18722 0.353902207950181 0.561747449692096 NNMT 1 GO:0048311 mitochondrion distribution 1/504 16/18722 0.353902207950181 0.561747449692096 MEF2A 1 GO:0048557 embryonic digestive tract morphogenesis 1/504 16/18722 0.353902207950181 0.561747449692096 PDGFRA 1 GO:0050862 positive regulation of T cell receptor signaling pathway 1/504 16/18722 0.353902207950181 0.561747449692096 CD81 1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1/504 16/18722 0.353902207950181 0.561747449692096 ADAM9 1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 1/504 16/18722 0.353902207950181 0.561747449692096 AKAP12 1 GO:0055089 fatty acid homeostasis 1/504 16/18722 0.353902207950181 0.561747449692096 XBP1 1 GO:0060572 morphogenesis of an epithelial bud 1/504 16/18722 0.353902207950181 0.561747449692096 WNT2 1 GO:0061684 chaperone-mediated autophagy 1/504 16/18722 0.353902207950181 0.561747449692096 SYNPO2 1 GO:0071361 cellular response to ethanol 1/504 16/18722 0.353902207950181 0.561747449692096 PTEN 1 GO:0071732 cellular response to nitric oxide 1/504 16/18722 0.353902207950181 0.561747449692096 FOXO1 1 GO:0072148 epithelial cell fate commitment 1/504 16/18722 0.353902207950181 0.561747449692096 NR2F2 1 GO:0097202 activation of cysteine-type endopeptidase activity 1/504 16/18722 0.353902207950181 0.561747449692096 IFI16 1 GO:0097284 hepatocyte apoptotic process 1/504 16/18722 0.353902207950181 0.561747449692096 GSN 1 GO:0099010 modification of postsynaptic structure 1/504 16/18722 0.353902207950181 0.561747449692096 ITSN1 1 GO:1901163 regulation of trophoblast cell migration 1/504 16/18722 0.353902207950181 0.561747449692096 TIMP1 1 GO:1904948 midbrain dopaminergic neuron differentiation 1/504 16/18722 0.353902207950181 0.561747449692096 WNT2 1 GO:1905906 regulation of amyloid fibril formation 1/504 16/18722 0.353902207950181 0.561747449692096 CRYAB 1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway 1/504 16/18722 0.353902207950181 0.561747449692096 GPC3 1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity 1/504 16/18722 0.353902207950181 0.561747449692096 ACTN4 1 GO:2000846 regulation of corticosteroid hormone secretion 1/504 16/18722 0.353902207950181 0.561747449692096 AGTR1 1 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/504 16/18722 0.353902207950181 0.561747449692096 GSN 1 GO:0072330 monocarboxylic acid biosynthetic process 7/504 214/18722 0.354572667025088 0.562602675899815 GATM/RBP1/LIPG/LPGAT1/XBP1/ELOVL5/ACLY 7 GO:0002821 positive regulation of adaptive immune response 4/504 112/18722 0.356166489673006 0.563935702488053 CD81/IL1R1/IL6ST/B2M 4 GO:0009141 nucleoside triphosphate metabolic process 4/504 112/18722 0.356166489673006 0.563935702488053 ENPP1/TMSB4X/RHOQ/STAT3 4 GO:0032609 interferon-gamma production 4/504 112/18722 0.356166489673006 0.563935702488053 GAS6/AXL/IL1R1/ISG15 4 GO:0032649 regulation of interferon-gamma production 4/504 112/18722 0.356166489673006 0.563935702488053 GAS6/AXL/IL1R1/ISG15 4 GO:0048640 negative regulation of developmental growth 4/504 112/18722 0.356166489673006 0.563935702488053 SEMA5A/MEIS1/CITED2/PTEN 4 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 8/504 249/18722 0.356204648026037 0.563935702488053 FLNA/LGALS1/LPAR1/MTDH/HSPB1/ZMYND11/S100A4/AKAP13 8 GO:0071897 DNA biosynthetic process 6/504 180/18722 0.356435905052727 0.564092823070482 PDGFRB/PARM1/HGF/REV3L/POLK/BMPR2 6 GO:0008202 steroid metabolic process 10/504 319/18722 0.357171024939028 0.564388774711026 IGFBP7/AGTR1/PDGFRA/LIMA1/EGR1/TSPO/CYB5R3/PBX1/ACLY/NFE2L1 10 GO:1901214 regulation of neuron death 10/504 319/18722 0.357171024939028 0.564388774711026 ITGA1/AXL/TGFB2/MEF2C/MDK/EGR1/HIPK2/JUN/STAT3/NCOA7 10 GO:1904951 positive regulation of establishment of protein localization 10/504 319/18722 0.357171024939028 0.564388774711026 CAMK2N1/FLNA/GAS6/TGFB2/CD81/SOX4/ADAM9/PIK3R1/STOM/TOMM7 10 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 5/504 146/18722 0.357283322160853 0.564388774711026 ADCY3/RAMP1/LPAR1/ATP2B4/AKAP13 5 GO:0045580 regulation of T cell differentiation 5/504 146/18722 0.357283322160853 0.564388774711026 MDK/SOX4/XBP1/ZMIZ1/SOS1 5 GO:1901184 regulation of ERBB signaling pathway 3/504 79/18722 0.3580828990202 0.565442803959097 ITGA1/HIP1/SOS1 3 GO:0097696 receptor signaling pathway via STAT 6/504 181/18722 0.361236746713919 0.569573400999404 IL6ST/CAV1/PKD2/JAK1/STAT3/STAT2 6 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 2/504 47/18722 0.362207989230984 0.569573400999404 AGTR1/TPM1 2 GO:0031641 regulation of myelination 2/504 47/18722 0.362207989230984 0.569573400999404 HGF/PTEN 2 GO:0032008 positive regulation of TOR signaling 2/504 47/18722 0.362207989230984 0.569573400999404 GAS6/AKT3 2 GO:0050885 neuromuscular process controlling balance 2/504 47/18722 0.362207989230984 0.569573400999404 RBFOX2/NBN 2 GO:0061001 regulation of dendritic spine morphogenesis 2/504 47/18722 0.362207989230984 0.569573400999404 PDLIM5/PTEN 2 GO:0072583 clathrin-dependent endocytosis 2/504 47/18722 0.362207989230984 0.569573400999404 HIP1/ITSN1 2 GO:0090279 regulation of calcium ion import 2/504 47/18722 0.362207989230984 0.569573400999404 PDGFRB/PKD2 2 GO:0120163 negative regulation of cold-induced thermogenesis 2/504 47/18722 0.362207989230984 0.569573400999404 LAMA4/ADAMTS5 2 GO:1903170 negative regulation of calcium ion transmembrane transport 2/504 47/18722 0.362207989230984 0.569573400999404 PKD2/CALM2 2 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 2/504 47/18722 0.362207989230984 0.569573400999404 THBS1/AGTR1 2 GO:0071347 cellular response to interleukin-1 4/504 113/18722 0.362298269112188 0.569573400999404 AKAP12/TFPI/IL1R1/EGR1 4 GO:0042176 regulation of protein catabolic process 12/504 391/18722 0.362902926560593 0.570314161527553 FLNA/TIMP1/FOXO1/GPC3/CD81/CAV1/TIMP2/TIMP3/HIPK2/MSN/ADAM9/PTEN 12 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 11/504 356/18722 0.363758525368417 0.571238580999355 C1R/C1S/JAG1/MEF2C/CD81/IL1R1/SERPING1/B2M/STAT3/NBN/AHR 11 GO:2001233 regulation of apoptotic signaling pathway 11/504 356/18722 0.363758525368417 0.571238580999355 THBS1/HGF/FGFR1/CAV1/TIMP3/HSPB1/ZMYND11/XBP1/ATF3/PTEN/PEA15 11 GO:0031331 positive regulation of cellular catabolic process 13/504 427/18722 0.36497447051906 0.572400659275545 DCN/FOXO1/MTDH/CD81/CAV1/KCNQ1OT1/ZFP36L1/ZFP36/ROCK2/MSN/ADAM9/PTEN/TNRC6B 13 GO:0009791 post-embryonic development 3/504 80/18722 0.36545047945909 0.572400659275545 FBN1/ARID5B/ATRX 3 GO:0021766 hippocampus development 3/504 80/18722 0.36545047945909 0.572400659275545 MDK/ATP2B4/PTEN 3 GO:0060401 cytosolic calcium ion transport 6/504 182/18722 0.366041364944161 0.572400659275545 THY1/SLC8A1/ATP2B4/CAV1/PKD2/CALM2 6 GO:0050905 neuromuscular process 5/504 148/18722 0.367985054779649 0.572400659275545 HIPK2/NR4A1/RBFOX2/PTEN/NBN 5 GO:2001056 positive regulation of cysteine-type endopeptidase activity 5/504 148/18722 0.367985054779649 0.572400659275545 DLC1/UACA/HIP1/GSN/IFI16 5 GO:1903008 organelle disassembly 4/504 114/18722 0.368428032573001 0.572400659275545 CTSK/TSPO/MAP1LC3A/TOMM7 4 GO:0002819 regulation of adaptive immune response 6/504 183/18722 0.370849005112623 0.572400659275545 MEF2C/CD81/IL1R1/IL6ST/B2M/AHR 6 GO:0001780 neutrophil homeostasis 1/504 17/18722 0.37131016727837 0.572400659275545 AXL 1 GO:0001829 trophectodermal cell differentiation 1/504 17/18722 0.37131016727837 0.572400659275545 CITED2 1 GO:0006474 N-terminal protein amino acid acetylation 1/504 17/18722 0.37131016727837 0.572400659275545 SOX4 1 GO:0009084 glutamine family amino acid biosynthetic process 1/504 17/18722 0.37131016727837 0.572400659275545 GLS 1 GO:0010224 response to UV-B 1/504 17/18722 0.37131016727837 0.572400659275545 CRIP1 1 GO:0010566 regulation of ketone biosynthetic process 1/504 17/18722 0.37131016727837 0.572400659275545 EGR1 1 GO:0014856 skeletal muscle cell proliferation 1/504 17/18722 0.37131016727837 0.572400659275545 STAT3 1 GO:0015867 ATP transport 1/504 17/18722 0.37131016727837 0.572400659275545 SLC25A24 1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 1/504 17/18722 0.37131016727837 0.572400659275545 B2M 1 GO:0030322 stabilization of membrane potential 1/504 17/18722 0.37131016727837 0.572400659275545 KCNK6 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/504 17/18722 0.37131016727837 0.572400659275545 TMEM50B 1 GO:0033623 regulation of integrin activation 1/504 17/18722 0.37131016727837 0.572400659275545 FERMT2 1 GO:0035518 histone H2A monoubiquitination 1/504 17/18722 0.37131016727837 0.572400659275545 PCGF5 1 GO:0035729 cellular response to hepatocyte growth factor stimulus 1/504 17/18722 0.37131016727837 0.572400659275545 HGF 1 GO:0035855 megakaryocyte development 1/504 17/18722 0.37131016727837 0.572400659275545 MEIS1 1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process 1/504 17/18722 0.37131016727837 0.572400659275545 INPP4B 1 GO:0036166 phenotypic switching 1/504 17/18722 0.37131016727837 0.572400659275545 MYOCD 1 GO:0042448 progesterone metabolic process 1/504 17/18722 0.37131016727837 0.572400659275545 EGR1 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/504 17/18722 0.37131016727837 0.572400659275545 CAV1 1 GO:0042772 DNA damage response, signal transduction resulting in transcription 1/504 17/18722 0.37131016727837 0.572400659275545 HIPK2 1 GO:0042953 lipoprotein transport 1/504 17/18722 0.37131016727837 0.572400659275545 VMP1 1 GO:0043968 histone H2A acetylation 1/504 17/18722 0.37131016727837 0.572400659275545 EPC1 1 GO:0044539 long-chain fatty acid import into cell 1/504 17/18722 0.37131016727837 0.572400659275545 THBS1 1 GO:0045815 positive regulation of gene expression, epigenetic 1/504 17/18722 0.37131016727837 0.572400659275545 ZMIZ1 1 GO:0046068 cGMP metabolic process 1/504 17/18722 0.37131016727837 0.572400659275545 GUCY1A2 1 GO:0046827 positive regulation of protein export from nucleus 1/504 17/18722 0.37131016727837 0.572400659275545 GAS6 1 GO:0051580 regulation of neurotransmitter uptake 1/504 17/18722 0.37131016727837 0.572400659275545 ITGB1 1 GO:0051797 regulation of hair follicle development 1/504 17/18722 0.37131016727837 0.572400659275545 TGFB2 1 GO:0055064 chloride ion homeostasis 1/504 17/18722 0.37131016727837 0.572400659275545 CKB 1 GO:0055083 monovalent inorganic anion homeostasis 1/504 17/18722 0.37131016727837 0.572400659275545 CKB 1 GO:0061450 trophoblast cell migration 1/504 17/18722 0.37131016727837 0.572400659275545 TIMP1 1 GO:0070206 protein trimerization 1/504 17/18722 0.37131016727837 0.572400659275545 COL1A2 1 GO:0090083 regulation of inclusion body assembly 1/504 17/18722 0.37131016727837 0.572400659275545 HSPA2 1 GO:0090136 epithelial cell-cell adhesion 1/504 17/18722 0.37131016727837 0.572400659275545 VCL 1 GO:0090713 immunological memory process 1/504 17/18722 0.37131016727837 0.572400659275545 CD81 1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity 1/504 17/18722 0.37131016727837 0.572400659275545 DLGAP4 1 GO:0140354 lipid import into cell 1/504 17/18722 0.37131016727837 0.572400659275545 THBS1 1 GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II 1/504 17/18722 0.37131016727837 0.572400659275545 NFIB 1 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1/504 17/18722 0.37131016727837 0.572400659275545 WWTR1 1 GO:0002686 negative regulation of leukocyte migration 2/504 48/18722 0.371929093910255 0.572400659275545 APOD/EMILIN1 2 GO:0032527 protein exit from endoplasmic reticulum 2/504 48/18722 0.371929093910255 0.572400659275545 CD81/HSP90B1 2 GO:0033628 regulation of cell adhesion mediated by integrin 2/504 48/18722 0.371929093910255 0.572400659275545 TGFB2/ADAM9 2 GO:0042149 cellular response to glucose starvation 2/504 48/18722 0.371929093910255 0.572400659275545 IFI16/XBP1 2 GO:0045912 negative regulation of carbohydrate metabolic process 2/504 48/18722 0.371929093910255 0.572400659275545 ENPP1/STAT3 2 GO:0061647 histone H3-K9 modification 2/504 48/18722 0.371929093910255 0.572400659275545 ATRX/KMT2A 2 GO:0050803 regulation of synapse structure or activity 7/504 218/18722 0.372149534025125 0.572400659275545 SPARC/TUBA1A/FARP1/PDLIM5/MEF2C/ITSN1/PTEN 7 GO:0097193 intrinsic apoptotic signaling pathway 9/504 288/18722 0.372238018964839 0.572400659275545 CRIP1/DYRK2/CAV1/HIPK2/IFI16/HSPB1/XBP1/PIK3R1/NBN 9 GO:1903311 regulation of mRNA metabolic process 9/504 288/18722 0.372238018964839 0.572400659275545 VIM/MBNL2/ZFP36L1/MBNL1/ZFP36/DDX17/ROCK2/RBFOX2/TNRC6B 9 GO:0001523 retinoid metabolic process 3/504 81/18722 0.372803892994113 0.572400659275545 RBP1/RARRES2/DHRS3 3 GO:0008589 regulation of smoothened signaling pathway 3/504 81/18722 0.372803892994113 0.572400659275545 ENPP1/GAS1/GPC3 3 GO:0044773 mitotic DNA damage checkpoint signaling 3/504 81/18722 0.372803892994113 0.572400659275545 SOX4/TAOK1/NBN 3 GO:0051149 positive regulation of muscle cell differentiation 3/504 81/18722 0.372803892994113 0.572400659275545 MYOCD/EFEMP2/MEF2C 3 GO:0071260 cellular response to mechanical stimulus 3/504 81/18722 0.372803892994113 0.572400659275545 COL1A1/SLC38A2/CNN2 3 GO:2000243 positive regulation of reproductive process 3/504 81/18722 0.372803892994113 0.572400659275545 PDE3A/EDNRB/CITED2 3 GO:0009411 response to UV 5/504 149/18722 0.373337763183487 0.572808711699476 TIMP1/MMP2/CRIP1/POLK/PIK3R1 5 GO:0032368 regulation of lipid transport 5/504 149/18722 0.373337763183487 0.572808711699476 THBS1/AGTR1/LIPG/CAV1/TSPO 5 GO:0000077 DNA damage checkpoint signaling 4/504 115/18722 0.37455430601023 0.574056868573068 SOX4/CLOCK/TAOK1/NBN 4 GO:0034968 histone lysine methylation 4/504 115/18722 0.37455430601023 0.574056868573068 NNMT/KMT2E/ATRX/KMT2A 4 GO:0051209 release of sequestered calcium ion into cytosol 4/504 115/18722 0.37455430601023 0.574056868573068 THY1/SLC8A1/PKD2/CALM2 4 GO:0007051 spindle organization 6/504 184/18722 0.375658919480542 0.575543407293065 FLNA/MYH9/MAP9/TACC1/MAP4/ATRX 6 GO:0071805 potassium ion transmembrane transport 7/504 219/18722 0.376552710328088 0.576547736471405 FHL1/FLNA/KCNK6/ITGB1/CAV1/PKD2/PTEN 7 GO:0009165 nucleotide biosynthetic process 8/504 254/18722 0.376584304350969 0.576547736471405 GUCY1A2/NNMT/ADCY3/PAPSS2/TMSB4X/ELOVL5/STAT3/ACLY 8 GO:0070665 positive regulation of leukocyte proliferation 5/504 150/18722 0.378690354320401 0.579459404087555 IGFBP2/MEF2C/CD81/IL6ST/IGF2 5 GO:0009205 purine ribonucleoside triphosphate metabolic process 3/504 82/18722 0.380140833441534 0.579459404087555 TMSB4X/RHOQ/STAT3 3 GO:1905897 regulation of response to endoplasmic reticulum stress 3/504 82/18722 0.380140833441534 0.579459404087555 CAV1/XBP1/PIK3R1 3 GO:0035967 cellular response to topologically incorrect protein 4/504 116/18722 0.380675643702703 0.579459404087555 HSPA2/XBP1/ATF3/PIK3R1 4 GO:0051283 negative regulation of sequestering of calcium ion 4/504 116/18722 0.380675643702703 0.579459404087555 THY1/SLC8A1/PKD2/CALM2 4 GO:0002762 negative regulation of myeloid leukocyte differentiation 2/504 49/18722 0.381590144868717 0.579459404087555 FBN1/PIK3R1 2 GO:0006778 porphyrin-containing compound metabolic process 2/504 49/18722 0.381590144868717 0.579459404087555 TSPO/NFE2L1 2 GO:0006953 acute-phase response 2/504 49/18722 0.381590144868717 0.579459404087555 EDNRB/STAT3 2 GO:0009409 response to cold 2/504 49/18722 0.381590144868717 0.579459404087555 FOXO1/HSPA2 2 GO:0010823 negative regulation of mitochondrion organization 2/504 49/18722 0.381590144868717 0.579459404087555 HGF/TSPO 2 GO:0018198 peptidyl-cysteine modification 2/504 49/18722 0.381590144868717 0.579459404087555 ATP2B4/NCOA7 2 GO:0021515 cell differentiation in spinal cord 2/504 49/18722 0.381590144868717 0.579459404087555 SOX4/SOX6 2 GO:0042304 regulation of fatty acid biosynthetic process 2/504 49/18722 0.381590144868717 0.579459404087555 LPGAT1/ELOVL5 2 GO:0050832 defense response to fungus 2/504 49/18722 0.381590144868717 0.579459404087555 SPON2/RARRES2 2 GO:0051445 regulation of meiotic cell cycle 2/504 49/18722 0.381590144868717 0.579459404087555 PDE3A/PRKAR1A 2 GO:0072091 regulation of stem cell proliferation 2/504 49/18722 0.381590144868717 0.579459404087555 FERMT2/ZFP36L1 2 GO:0086009 membrane repolarization 2/504 49/18722 0.381590144868717 0.579459404087555 FLNA/CAV1 2 GO:1901293 nucleoside phosphate biosynthetic process 8/504 256/18722 0.384760041555117 0.579459404087555 GUCY1A2/NNMT/ADCY3/PAPSS2/TMSB4X/ELOVL5/STAT3/ACLY 8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 6/504 186/18722 0.38528261568847 0.579459404087555 FLNA/LGALS1/LPAR1/MTDH/S100A4/AKAP13 6 GO:0030301 cholesterol transport 4/504 117/18722 0.386790628530202 0.579459404087555 LIPG/CAV1/LIMA1/TSPO 4 GO:1903828 negative regulation of cellular protein localization 4/504 117/18722 0.386790628530202 0.579459404087555 APOD/PKIG/RHOQ/ROCK2 4 GO:0042391 regulation of membrane potential 13/504 434/18722 0.386897748179641 0.579459404087555 DCN/GJC1/FXYD1/FHL1/FLNA/SLMAP/KCNK6/MEF2C/SLC8A1/CAV1/TSPO/JUN/PTEN 13 GO:0050672 negative regulation of lymphocyte proliferation 3/504 83/18722 0.387459067446103 0.579459404087555 LRRC32/TWSG1/PRKAR1A 3 GO:0001946 lymphangiogenesis 1/504 18/18722 0.388250005593885 0.579459404087555 BMPR2 1 GO:0002295 T-helper cell lineage commitment 1/504 18/18722 0.388250005593885 0.579459404087555 STAT3 1 GO:0002501 peptide antigen assembly with MHC protein complex 1/504 18/18722 0.388250005593885 0.579459404087555 B2M 1 GO:0002544 chronic inflammatory response 1/504 18/18722 0.388250005593885 0.579459404087555 THBS1 1 GO:0003417 growth plate cartilage development 1/504 18/18722 0.388250005593885 0.579459404087555 COL27A1 1 GO:0006085 acetyl-CoA biosynthetic process 1/504 18/18722 0.388250005593885 0.579459404087555 ACLY 1 GO:0006595 polyamine metabolic process 1/504 18/18722 0.388250005593885 0.579459404087555 NNMT 1 GO:0010663 positive regulation of striated muscle cell apoptotic process 1/504 18/18722 0.388250005593885 0.579459404087555 PTEN 1 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 1/504 18/18722 0.388250005593885 0.579459404087555 PTEN 1 GO:0015936 coenzyme A metabolic process 1/504 18/18722 0.388250005593885 0.579459404087555 ACLY 1 GO:0019896 axonal transport of mitochondrion 1/504 18/18722 0.388250005593885 0.579459404087555 ARMCX3 1 GO:0030206 chondroitin sulfate biosynthetic process 1/504 18/18722 0.388250005593885 0.579459404087555 UGDH 1 GO:0030299 intestinal cholesterol absorption 1/504 18/18722 0.388250005593885 0.579459404087555 LIMA1 1 GO:0030728 ovulation 1/504 18/18722 0.388250005593885 0.579459404087555 ADAMTS1 1 GO:0030730 sequestering of triglyceride 1/504 18/18722 0.388250005593885 0.579459404087555 ENPP1 1 GO:0031000 response to caffeine 1/504 18/18722 0.388250005593885 0.579459404087555 SLC8A1 1 GO:0031643 positive regulation of myelination 1/504 18/18722 0.388250005593885 0.579459404087555 HGF 1 GO:0031649 heat generation 1/504 18/18722 0.388250005593885 0.579459404087555 EDNRB 1 GO:0033189 response to vitamin A 1/504 18/18722 0.388250005593885 0.579459404087555 MAP1B 1 GO:0034134 toll-like receptor 2 signaling pathway 1/504 18/18722 0.388250005593885 0.579459404087555 PJA2 1 GO:0034433 steroid esterification 1/504 18/18722 0.388250005593885 0.579459404087555 AGTR1 1 GO:0034434 sterol esterification 1/504 18/18722 0.388250005593885 0.579459404087555 AGTR1 1 GO:0034435 cholesterol esterification 1/504 18/18722 0.388250005593885 0.579459404087555 AGTR1 1 GO:0035930 corticosteroid hormone secretion 1/504 18/18722 0.388250005593885 0.579459404087555 AGTR1 1 GO:0043217 myelin maintenance 1/504 18/18722 0.388250005593885 0.579459404087555 PTEN 1 GO:0044872 lipoprotein localization 1/504 18/18722 0.388250005593885 0.579459404087555 VMP1 1 GO:0048268 clathrin coat assembly 1/504 18/18722 0.388250005593885 0.579459404087555 HIP1 1 GO:0048535 lymph node development 1/504 18/18722 0.388250005593885 0.579459404087555 CD248 1 GO:0050665 hydrogen peroxide biosynthetic process 1/504 18/18722 0.388250005593885 0.579459404087555 STAT3 1 GO:0051447 negative regulation of meiotic cell cycle 1/504 18/18722 0.388250005593885 0.579459404087555 PRKAR1A 1 GO:0051782 negative regulation of cell division 1/504 18/18722 0.388250005593885 0.579459404087555 TXNIP 1 GO:0060546 negative regulation of necroptotic process 1/504 18/18722 0.388250005593885 0.579459404087555 CAV1 1 GO:0060602 branch elongation of an epithelium 1/504 18/18722 0.388250005593885 0.579459404087555 SPRY1 1 GO:0060716 labyrinthine layer blood vessel development 1/504 18/18722 0.388250005593885 0.579459404087555 WNT2 1 GO:0061687 detoxification of inorganic compound 1/504 18/18722 0.388250005593885 0.579459404087555 MT1E 1 GO:0071071 regulation of phospholipid biosynthetic process 1/504 18/18722 0.388250005593885 0.579459404087555 PDGFA 1 GO:0071318 cellular response to ATP 1/504 18/18722 0.388250005593885 0.579459404087555 HSP90B1 1 GO:0071360 cellular response to exogenous dsRNA 1/504 18/18722 0.388250005593885 0.579459404087555 CAV1 1 GO:0071786 endoplasmic reticulum tubular network organization 1/504 18/18722 0.388250005593885 0.579459404087555 ATL3 1 GO:0072189 ureter development 1/504 18/18722 0.388250005593885 0.579459404087555 NFIA 1 GO:0090493 catecholamine uptake 1/504 18/18722 0.388250005593885 0.579459404087555 ACTB 1 GO:0097107 postsynaptic density assembly 1/504 18/18722 0.388250005593885 0.579459404087555 PTEN 1 GO:0099558 maintenance of synapse structure 1/504 18/18722 0.388250005593885 0.579459404087555 CTBP2 1 GO:0110154 RNA decapping 1/504 18/18722 0.388250005593885 0.579459404087555 ZFP36 1 GO:1902001 fatty acid transmembrane transport 1/504 18/18722 0.388250005593885 0.579459404087555 THBS1 1 GO:1902170 cellular response to reactive nitrogen species 1/504 18/18722 0.388250005593885 0.579459404087555 FOXO1 1 GO:1902683 regulation of receptor localization to synapse 1/504 18/18722 0.388250005593885 0.579459404087555 NPTN 1 GO:2000641 regulation of early endosome to late endosome transport 1/504 18/18722 0.388250005593885 0.579459404087555 MSN 1 GO:2001135 regulation of endocytic recycling 1/504 18/18722 0.388250005593885 0.579459404087555 EHD2 1 GO:0005996 monosaccharide metabolic process 8/504 257/18722 0.388851187466339 0.580154023758264 IGFBP4/NNMT/APOD/ENPP1/DYRK2/IGF2/ATF3/MAN2A1 8 GO:0002695 negative regulation of leukocyte activation 6/504 187/18722 0.39009493853203 0.581806517398731 LRRC32/AXL/PAG1/TWSG1/MDK/PRKAR1A 6 GO:0007632 visual behavior 2/504 50/18722 0.391187331639438 0.582419326862481 ITGB1/NPTN 2 GO:0043268 positive regulation of potassium ion transport 2/504 50/18722 0.391187331639438 0.582419326862481 FHL1/FLNA 2 GO:0090102 cochlea development 2/504 50/18722 0.391187331639438 0.582419326862481 CTHRC1/PTK7 2 GO:0099054 presynapse assembly 2/504 50/18722 0.391187331639438 0.582419326862481 FARP1/PTEN 2 GO:2000677 regulation of transcription regulatory region DNA binding 2/504 50/18722 0.391187331639438 0.582419326862481 HAND2/TMSB4X 2 GO:0006413 translational initiation 4/504 118/18722 0.392897872213667 0.584355241200487 EIF4G3/HSPB1/EIF4EBP1/EIF4EBP2 4 GO:0051282 regulation of sequestering of calcium ion 4/504 118/18722 0.392897872213667 0.584355241200487 THY1/SLC8A1/PKD2/CALM2 4 GO:1903313 positive regulation of mRNA metabolic process 4/504 118/18722 0.392897872213667 0.584355241200487 ZFP36L1/ZFP36/ROCK2/TNRC6B 4 GO:0032508 DNA duplex unwinding 3/504 84/18722 0.394756433883472 0.586507038242029 CHD9/ATRX/NBN 3 GO:0032945 negative regulation of mononuclear cell proliferation 3/504 84/18722 0.394756433883472 0.586507038242029 LRRC32/TWSG1/PRKAR1A 3 GO:0042440 pigment metabolic process 3/504 84/18722 0.394756433883472 0.586507038242029 ZEB2/TSPO/NFE2L1 3 GO:0006575 cellular modified amino acid metabolic process 6/504 188/18722 0.394906617995941 0.586526235209126 GATM/CTSK/CKB/PCYOX1/PLOD2/GSTM3 6 GO:0014009 glial cell proliferation 2/504 51/18722 0.400717091556285 0.59267635635347 SOX4/TSPO 2 GO:0021872 forebrain generation of neurons 2/504 51/18722 0.400717091556285 0.59267635635347 B2M/ZMIZ1 2 GO:0048013 ephrin receptor signaling pathway 2/504 51/18722 0.400717091556285 0.59267635635347 CHN1/MMP2 2 GO:0051339 regulation of lyase activity 2/504 51/18722 0.400717091556285 0.59267635635347 EDNRB/TIMP2 2 GO:0065002 intracellular protein transmembrane transport 2/504 51/18722 0.400717091556285 0.59267635635347 TOMM7/SEC62 2 GO:0044774 mitotic DNA integrity checkpoint signaling 3/504 85/18722 0.402030843198208 0.59267635635347 SOX4/TAOK1/NBN 3 GO:0097006 regulation of plasma lipoprotein particle levels 3/504 85/18722 0.402030843198208 0.59267635635347 PLA2G2A/AGTR1/LIPG 3 GO:0050804 modulation of chemical synaptic transmission 13/504 439/18722 0.402639129281237 0.59267635635347 MAP1B/LAMA2/AKAP12/CDH11/MEF2C/ITGB1/PREPL/STAT3/NPTN/PTEN/PTPRA/EIF4EBP2/DLGAP4 13 GO:0002396 MHC protein complex assembly 1/504 19/18722 0.404734286880277 0.59267635635347 B2M 1 GO:0002483 antigen processing and presentation of endogenous peptide antigen 1/504 19/18722 0.404734286880277 0.59267635635347 B2M 1 GO:0002523 leukocyte migration involved in inflammatory response 1/504 19/18722 0.404734286880277 0.59267635635347 MDK 1 GO:0002902 regulation of B cell apoptotic process 1/504 19/18722 0.404734286880277 0.59267635635347 PTEN 1 GO:0006491 N-glycan processing 1/504 19/18722 0.404734286880277 0.59267635635347 MAN2A1 1 GO:0006670 sphingosine metabolic process 1/504 19/18722 0.404734286880277 0.59267635635347 PLPP1 1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1/504 19/18722 0.404734286880277 0.59267635635347 SOX4 1 GO:0007039 protein catabolic process in the vacuole 1/504 19/18722 0.404734286880277 0.59267635635347 CD81 1 GO:0007530 sex determination 1/504 19/18722 0.404734286880277 0.59267635635347 CITED2 1 GO:0009226 nucleotide-sugar biosynthetic process 1/504 19/18722 0.404734286880277 0.59267635635347 UGDH 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/504 19/18722 0.404734286880277 0.59267635635347 PTEN 1 GO:0030011 maintenance of cell polarity 1/504 19/18722 0.404734286880277 0.59267635635347 DST 1 GO:0032026 response to magnesium ion 1/504 19/18722 0.404734286880277 0.59267635635347 THBS1 1 GO:0032695 negative regulation of interleukin-12 production 1/504 19/18722 0.404734286880277 0.59267635635347 THBS1 1 GO:0033194 response to hydroperoxide 1/504 19/18722 0.404734286880277 0.59267635635347 MGST1 1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 1/504 19/18722 0.404734286880277 0.59267635635347 ELOVL5 1 GO:0035728 response to hepatocyte growth factor 1/504 19/18722 0.404734286880277 0.59267635635347 HGF 1 GO:0036498 IRE1-mediated unfolded protein response 1/504 19/18722 0.404734286880277 0.59267635635347 XBP1 1 GO:0038092 nodal signaling pathway 1/504 19/18722 0.404734286880277 0.59267635635347 CITED2 1 GO:0042474 middle ear morphogenesis 1/504 19/18722 0.404734286880277 0.59267635635347 TSHZ1 1 GO:0043652 engulfment of apoptotic cell 1/504 19/18722 0.404734286880277 0.59267635635347 THBS1 1 GO:0045603 positive regulation of endothelial cell differentiation 1/504 19/18722 0.404734286880277 0.59267635635347 VEZF1 1 GO:0046716 muscle cell cellular homeostasis 1/504 19/18722 0.404734286880277 0.59267635635347 CFL2 1 GO:0051957 positive regulation of amino acid transport 1/504 19/18722 0.404734286880277 0.59267635635347 ITGB1 1 GO:0061760 antifungal innate immune response 1/504 19/18722 0.404734286880277 0.59267635635347 RARRES2 1 GO:0062099 negative regulation of programmed necrotic cell death 1/504 19/18722 0.404734286880277 0.59267635635347 CAV1 1 GO:0097501 stress response to metal ion 1/504 19/18722 0.404734286880277 0.59267635635347 MT1E 1 GO:0098780 response to mitochondrial depolarisation 1/504 19/18722 0.404734286880277 0.59267635635347 TOMM7 1 GO:1900221 regulation of amyloid-beta clearance 1/504 19/18722 0.404734286880277 0.59267635635347 MYOCD 1 GO:1901739 regulation of myoblast fusion 1/504 19/18722 0.404734286880277 0.59267635635347 EHD2 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/504 19/18722 0.404734286880277 0.59267635635347 NCOA7 1 GO:2000269 regulation of fibroblast apoptotic process 1/504 19/18722 0.404734286880277 0.59267635635347 GAS6 1 GO:2000831 regulation of steroid hormone secretion 1/504 19/18722 0.404734286880277 0.59267635635347 AGTR1 1 GO:0007052 mitotic spindle organization 4/504 120/18722 0.405083728432758 0.592984848096326 FLNA/MAP9/TACC1/MAP4 4 GO:0010970 transport along microtubule 5/504 155/18722 0.405417315340851 0.593066822475679 MAP1B/DST/HSPB1/ARL3/ARMCX3 5 GO:0046434 organophosphate catabolic process 5/504 155/18722 0.405417315340851 0.593066822475679 PDE8B/ENPP1/INPP4B/LIPG/PTEN 5 GO:0099177 regulation of trans-synaptic signaling 13/504 440/18722 0.405792891773357 0.593413082322915 MAP1B/LAMA2/AKAP12/CDH11/MEF2C/ITGB1/PREPL/STAT3/NPTN/PTEN/PTPRA/EIF4EBP2/DLGAP4 13 GO:0009798 axis specification 3/504 86/18722 0.409280276682466 0.598308115725001 GPC3/CITED2/NOTCH2 3 GO:0021545 cranial nerve development 2/504 52/18722 0.410176099219922 0.598798248024163 EXT1/CITED2 2 GO:0032206 positive regulation of telomere maintenance 2/504 52/18722 0.410176099219922 0.598798248024163 ATRX/NBN 2 GO:0048260 positive regulation of receptor-mediated endocytosis 2/504 52/18722 0.410176099219922 0.598798248024163 HIP1/B2M 2 GO:2000378 negative regulation of reactive oxygen species metabolic process 2/504 52/18722 0.410176099219922 0.598798248024163 CRYAB/STAT3 2 GO:0002455 humoral immune response mediated by circulating immunoglobulin 4/504 121/18722 0.411159710290061 0.600029181034641 C1R/C1S/CD81/SERPING1 4 GO:0098657 import into cell 7/504 227/18722 0.411818336671185 0.600785166471824 THBS1/CYBRD1/ITGB1/SLC8A1/ACTB/ATP2B4/SLC39A6 7 GO:0001776 leukocyte homeostasis 3/504 87/18722 0.416502785700076 0.604360535932889 AXL/MEF2C/SOS1 3 GO:0007029 endoplasmic reticulum organization 3/504 87/18722 0.416502785700076 0.604360535932889 ATL3/SEC31A/CAV2 3 GO:0016101 diterpenoid metabolic process 3/504 87/18722 0.416502785700076 0.604360535932889 RBP1/RARRES2/DHRS3 3 GO:0051262 protein tetramerization 3/504 87/18722 0.416502785700076 0.604360535932889 B2M/PKD2/GLS 3 GO:1901606 alpha-amino acid catabolic process 3/504 87/18722 0.416502785700076 0.604360535932889 ATP2B4/DDAH2/GLS 3 GO:2000177 regulation of neural precursor cell proliferation 3/504 87/18722 0.416502785700076 0.604360535932889 FLNA/LIMS2/MDK 3 GO:0002688 regulation of leukocyte chemotaxis 4/504 122/18722 0.417222689890885 0.604360535932889 THBS1/RARRES2/GAS6/MDK 4 GO:0031109 microtubule polymerization or depolymerization 4/504 122/18722 0.417222689890885 0.604360535932889 CRYAB/MAP1B/ARL3/TAOK1 4 GO:0015833 peptide transport 8/504 264/18722 0.417508488211862 0.604360535932889 CAMK2N1/LTBP4/MGST1/SOX4/MAP4K4/ITSN1/CLOCK/RAB11FIP2 8 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 8/504 264/18722 0.417508488211862 0.604360535932889 THY1/HGF/GAS6/CD81/IL6ST/CAV1/IGF2/PDGFA 8 GO:0099172 presynapse organization 2/504 53/18722 0.419561256349546 0.604360535932889 FARP1/PTEN 2 GO:2000772 regulation of cellular senescence 2/504 53/18722 0.419561256349546 0.604360535932889 B2M/AKT3 2 GO:0001832 blastocyst growth 1/504 20/18722 0.420775238567832 0.604360535932889 NBN 1 GO:0002577 regulation of antigen processing and presentation 1/504 20/18722 0.420775238567832 0.604360535932889 THBS1 1 GO:0002834 regulation of response to tumor cell 1/504 20/18722 0.420775238567832 0.604360535932889 AHR 1 GO:0002837 regulation of immune response to tumor cell 1/504 20/18722 0.420775238567832 0.604360535932889 AHR 1 GO:0006590 thyroid hormone generation 1/504 20/18722 0.420775238567832 0.604360535932889 CTSK 1 GO:0006607 NLS-bearing protein import into nucleus 1/504 20/18722 0.420775238567832 0.604360535932889 KPNA3 1 GO:0006883 cellular sodium ion homeostasis 1/504 20/18722 0.420775238567832 0.604360535932889 SLC8A1 1 GO:0007194 negative regulation of adenylate cyclase activity 1/504 20/18722 0.420775238567832 0.604360535932889 EDNRB 1 GO:0007620 copulation 1/504 20/18722 0.420775238567832 0.604360535932889 EDNRB 1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1/504 20/18722 0.420775238567832 0.604360535932889 CALM2 1 GO:0030150 protein import into mitochondrial matrix 1/504 20/18722 0.420775238567832 0.604360535932889 TOMM7 1 GO:0031645 negative regulation of nervous system process 1/504 20/18722 0.420775238567832 0.604360535932889 PTEN 1 GO:0032332 positive regulation of chondrocyte differentiation 1/504 20/18722 0.420775238567832 0.604360535932889 SOX6 1 GO:0043011 myeloid dendritic cell differentiation 1/504 20/18722 0.420775238567832 0.604360535932889 NOTCH2 1 GO:0043586 tongue development 1/504 20/18722 0.420775238567832 0.604360535932889 HAND2 1 GO:0043651 linoleic acid metabolic process 1/504 20/18722 0.420775238567832 0.604360535932889 ELOVL5 1 GO:0043691 reverse cholesterol transport 1/504 20/18722 0.420775238567832 0.604360535932889 LIPG 1 GO:0043984 histone H4-K16 acetylation 1/504 20/18722 0.420775238567832 0.604360535932889 KMT2A 1 GO:0046629 gamma-delta T cell activation 1/504 20/18722 0.420775238567832 0.604360535932889 SOX4 1 GO:0060252 positive regulation of glial cell proliferation 1/504 20/18722 0.420775238567832 0.604360535932889 TSPO 1 GO:0070166 enamel mineralization 1/504 20/18722 0.420775238567832 0.604360535932889 FOXO1 1 GO:0070932 histone H3 deacetylation 1/504 20/18722 0.420775238567832 0.604360535932889 HDAC7 1 GO:0071625 vocalization behavior 1/504 20/18722 0.420775238567832 0.604360535932889 EXT1 1 GO:0071731 response to nitric oxide 1/504 20/18722 0.420775238567832 0.604360535932889 FOXO1 1 GO:0090201 negative regulation of release of cytochrome c from mitochondria 1/504 20/18722 0.420775238567832 0.604360535932889 HGF 1 GO:0097150 neuronal stem cell population maintenance 1/504 20/18722 0.420775238567832 0.604360535932889 JAG1 1 GO:0097320 plasma membrane tubulation 1/504 20/18722 0.420775238567832 0.604360535932889 EHD2 1 GO:1902004 positive regulation of amyloid-beta formation 1/504 20/18722 0.420775238567832 0.604360535932889 ROCK2 1 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1/504 20/18722 0.420775238567832 0.604360535932889 HSPB1 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/504 20/18722 0.420775238567832 0.604360535932889 XBP1 1 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 1/504 20/18722 0.420775238567832 0.604360535932889 HGF 1 GO:1903817 negative regulation of voltage-gated potassium channel activity 1/504 20/18722 0.420775238567832 0.604360535932889 CAV1 1 GO:1904292 regulation of ERAD pathway 1/504 20/18722 0.420775238567832 0.604360535932889 CAV1 1 GO:2000678 negative regulation of transcription regulatory region DNA binding 1/504 20/18722 0.420775238567832 0.604360535932889 TMSB4X 1 GO:0043488 regulation of mRNA stability 5/504 158/18722 0.421390769507976 0.605041249364107 VIM/ZFP36L1/ZFP36/ROCK2/TNRC6B 5 GO:0031570 DNA integrity checkpoint signaling 4/504 123/18722 0.423271425571078 0.6075352702844 SOX4/CLOCK/TAOK1/NBN 4 GO:0009144 purine nucleoside triphosphate metabolic process 3/504 88/18722 0.423696490860639 0.6075352702844 TMSB4X/RHOQ/STAT3 3 GO:0030101 natural killer cell activation 3/504 88/18722 0.423696490860639 0.6075352702844 GAS6/AXL/PBX1 3 GO:0031110 regulation of microtubule polymerization or depolymerization 3/504 88/18722 0.423696490860639 0.6075352702844 MAP1B/ARL3/TAOK1 3 GO:0030595 leukocyte chemotaxis 7/504 230/18722 0.425025046040114 0.609235834193026 ITGA1/THBS1/RARRES2/GAS6/TGFB2/MDK/EDNRB 7 GO:0006968 cellular defense response 2/504 54/18722 0.428869682007274 0.613717398264261 ITGB1/VEZF1 2 GO:0035065 regulation of histone acetylation 2/504 54/18722 0.428869682007274 0.613717398264261 MYOCD/KMT2A 2 GO:0043647 inositol phosphate metabolic process 2/504 54/18722 0.428869682007274 0.613717398264261 INPP4B/PTEN 2 GO:1902743 regulation of lamellipodium organization 2/504 54/18722 0.428869682007274 0.613717398264261 NCKAP1/PIK3R1 2 GO:2000179 positive regulation of neural precursor cell proliferation 2/504 54/18722 0.428869682007274 0.613717398264261 FLNA/MDK 2 GO:0002253 activation of immune response 11/504 375/18722 0.429092796702841 0.613824081903512 THY1/C1R/CFH/C1S/A2M/MEF2C/CD81/SERPING1/IFI16/CMTM3/CFD 11 GO:0045732 positive regulation of protein catabolic process 7/504 231/18722 0.429420843021917 0.613824081903512 FOXO1/GPC3/CD81/CAV1/MSN/ADAM9/PTEN 7 GO:0002697 regulation of immune effector process 10/504 339/18722 0.429518840367775 0.613824081903512 SPON2/CFH/TGFB2/A2M/CD81/IL1R1/SERPING1/B2M/XBP1/AHR 10 GO:0006790 sulfur compound metabolic process 10/504 339/18722 0.429518840367775 0.613824081903512 DCN/ENPP1/PAPSS2/BGN/EXT1/DSEL/UGDH/ELOVL5/ACLY/GSTM3 10 GO:0009199 ribonucleoside triphosphate metabolic process 3/504 89/18722 0.430859581147919 0.615328539520407 TMSB4X/RHOQ/STAT3 3 GO:0046330 positive regulation of JNK cascade 3/504 89/18722 0.430859581147919 0.615328539520407 HIPK2/PJA2/TAOK1 3 GO:0006925 inflammatory cell apoptotic process 1/504 21/18722 0.436384760531355 0.616216814854753 MEF2C 1 GO:0007063 regulation of sister chromatid cohesion 1/504 21/18722 0.436384760531355 0.616216814854753 ATRX 1 GO:0007617 mating behavior 1/504 21/18722 0.436384760531355 0.616216814854753 PTEN 1 GO:0008090 retrograde axonal transport 1/504 21/18722 0.436384760531355 0.616216814854753 DST 1 GO:0009067 aspartate family amino acid biosynthetic process 1/504 21/18722 0.436384760531355 0.616216814854753 PLOD2 1 GO:0022010 central nervous system myelination 1/504 21/18722 0.436384760531355 0.616216814854753 PTEN 1 GO:0023019 signal transduction involved in regulation of gene expression 1/504 21/18722 0.436384760531355 0.616216814854753 PDGFRA 1 GO:0030502 negative regulation of bone mineralization 1/504 21/18722 0.436384760531355 0.616216814854753 ENPP1 1 GO:0032288 myelin assembly 1/504 21/18722 0.436384760531355 0.616216814854753 PMP22 1 GO:0032291 axon ensheathment in central nervous system 1/504 21/18722 0.436384760531355 0.616216814854753 PTEN 1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 1/504 21/18722 0.436384760531355 0.616216814854753 NCKAP1 1 GO:0038083 peptidyl-tyrosine autophosphorylation 1/504 21/18722 0.436384760531355 0.616216814854753 CAV1 1 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 1/504 21/18722 0.436384760531355 0.616216814854753 STAT3 1 GO:0043576 regulation of respiratory gaseous exchange 1/504 21/18722 0.436384760531355 0.616216814854753 GLS 1 GO:0044241 lipid digestion 1/504 21/18722 0.436384760531355 0.616216814854753 LIMA1 1 GO:0046519 sphingoid metabolic process 1/504 21/18722 0.436384760531355 0.616216814854753 PLPP1 1 GO:0046641 positive regulation of alpha-beta T cell proliferation 1/504 21/18722 0.436384760531355 0.616216814854753 CD81 1 GO:0046885 regulation of hormone biosynthetic process 1/504 21/18722 0.436384760531355 0.616216814854753 EGR1 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/504 21/18722 0.436384760531355 0.616216814854753 MDK 1 GO:0051767 nitric-oxide synthase biosynthetic process 1/504 21/18722 0.436384760531355 0.616216814854753 AKAP12 1 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1/504 21/18722 0.436384760531355 0.616216814854753 AKAP12 1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1/504 21/18722 0.436384760531355 0.616216814854753 SPON2 1 GO:0071605 monocyte chemotactic protein-1 production 1/504 21/18722 0.436384760531355 0.616216814854753 APOD 1 GO:0071637 regulation of monocyte chemotactic protein-1 production 1/504 21/18722 0.436384760531355 0.616216814854753 APOD 1 GO:0090141 positive regulation of mitochondrial fission 1/504 21/18722 0.436384760531355 0.616216814854753 DCN 1 GO:0098698 postsynaptic specialization assembly 1/504 21/18722 0.436384760531355 0.616216814854753 PTEN 1 GO:0098719 sodium ion import across plasma membrane 1/504 21/18722 0.436384760531355 0.616216814854753 SLC8A1 1 GO:0098856 intestinal lipid absorption 1/504 21/18722 0.436384760531355 0.616216814854753 LIMA1 1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 1/504 21/18722 0.436384760531355 0.616216814854753 STAT3 1 GO:1903429 regulation of cell maturation 1/504 21/18722 0.436384760531355 0.616216814854753 EDNRB 1 GO:2000047 regulation of cell-cell adhesion mediated by cadherin 1/504 21/18722 0.436384760531355 0.616216814854753 TJP1 1 GO:2000178 negative regulation of neural precursor cell proliferation 1/504 21/18722 0.436384760531355 0.616216814854753 LIMS2 1 GO:2000291 regulation of myoblast proliferation 1/504 21/18722 0.436384760531355 0.616216814854753 MALAT1 1 GO:2000774 positive regulation of cellular senescence 1/504 21/18722 0.436384760531355 0.616216814854753 B2M 1 GO:0032392 DNA geometric change 3/504 90/18722 0.43799031300662 0.616802556408259 CHD9/ATRX/NBN 3 GO:0035278 miRNA mediated inhibition of translation 3/504 90/18722 0.43799031300662 0.616802556408259 ZFP36/STAT3/TNRC6B 3 GO:0040033 negative regulation of translation, ncRNA-mediated 3/504 90/18722 0.43799031300662 0.616802556408259 ZFP36/STAT3/TNRC6B 3 GO:0061097 regulation of protein tyrosine kinase activity 3/504 90/18722 0.43799031300662 0.616802556408259 THY1/GAS6/CAV1 3 GO:0070664 negative regulation of leukocyte proliferation 3/504 90/18722 0.43799031300662 0.616802556408259 LRRC32/TWSG1/PRKAR1A 3 GO:0002067 glandular epithelial cell differentiation 2/504 55/18722 0.438098703182557 0.616802556408259 EXT1/CLOCK 2 GO:0031113 regulation of microtubule polymerization 2/504 55/18722 0.438098703182557 0.616802556408259 MAP1B/ARL3 2 GO:0046164 alcohol catabolic process 2/504 55/18722 0.438098703182557 0.616802556408259 INPP4B/PTEN 2 GO:0098900 regulation of action potential 2/504 55/18722 0.438098703182557 0.616802556408259 FLNA/CAV1 2 GO:0031929 TOR signaling 4/504 126/18722 0.441320196289656 0.621133464672496 GAS6/EIF4EBP1/AKT3/EIF4EBP2 4 GO:0045974 regulation of translation, ncRNA-mediated 3/504 91/18722 0.445087009391451 0.626228775478982 ZFP36/STAT3/TNRC6B 3 GO:0010332 response to gamma radiation 2/504 56/18722 0.447245845724351 0.628514785158989 CRYAB/EGR1 2 GO:0022029 telencephalon cell migration 2/504 56/18722 0.447245845724351 0.628514785158989 LAMB1/ZMIZ1 2 GO:0042733 embryonic digit morphogenesis 2/504 56/18722 0.447245845724351 0.628514785158989 TBX2/HAND2 2 GO:0006911 phagocytosis, engulfment 4/504 127/18722 0.447300131445936 0.628514785158989 THBS1/MFGE8/MYH9/GSN 4 GO:0006633 fatty acid biosynthetic process 5/504 163/18722 0.447831502151515 0.628847850375755 LIPG/LPGAT1/XBP1/ELOVL5/ACLY 5 GO:0010976 positive regulation of neuron projection development 5/504 163/18722 0.447831502151515 0.628847850375755 HGF/FLNA/MDK/PTK7/NPTN 5 GO:0030072 peptide hormone secretion 7/504 236/18722 0.451328586668815 0.628936621848748 CAMK2N1/LTBP4/SOX4/MAP4K4/ITSN1/CLOCK/RAB11FIP2 7 GO:0007413 axonal fasciculation 1/504 22/18722 0.451574433847873 0.628936621848748 SEMA5A 1 GO:0010310 regulation of hydrogen peroxide metabolic process 1/504 22/18722 0.451574433847873 0.628936621848748 STAT3 1 GO:0021854 hypothalamus development 1/504 22/18722 0.451574433847873 0.628936621848748 ETS1 1 GO:0022616 DNA strand elongation 1/504 22/18722 0.451574433847873 0.628936621848748 NBN 1 GO:0031281 positive regulation of cyclase activity 1/504 22/18722 0.451574433847873 0.628936621848748 TIMP2 1 GO:0032891 negative regulation of organic acid transport 1/504 22/18722 0.451574433847873 0.628936621848748 THBS1 1 GO:0035561 regulation of chromatin binding 1/504 22/18722 0.451574433847873 0.628936621848748 CTBP2 1 GO:0035809 regulation of urine volume 1/504 22/18722 0.451574433847873 0.628936621848748 EDNRB 1 GO:0036120 cellular response to platelet-derived growth factor stimulus 1/504 22/18722 0.451574433847873 0.628936621848748 PDGFRB 1 GO:0044346 fibroblast apoptotic process 1/504 22/18722 0.451574433847873 0.628936621848748 GAS6 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/504 22/18722 0.451574433847873 0.628936621848748 IGF2 1 GO:0048169 regulation of long-term neuronal synaptic plasticity 1/504 22/18722 0.451574433847873 0.628936621848748 NPTN 1 GO:0050860 negative regulation of T cell receptor signaling pathway 1/504 22/18722 0.451574433847873 0.628936621848748 THY1 1 GO:0060563 neuroepithelial cell differentiation 1/504 22/18722 0.451574433847873 0.628936621848748 SOX4 1 GO:0060713 labyrinthine layer morphogenesis 1/504 22/18722 0.451574433847873 0.628936621848748 ZFP36L1 1 GO:0071359 cellular response to dsRNA 1/504 22/18722 0.451574433847873 0.628936621848748 CAV1 1 GO:0090280 positive regulation of calcium ion import 1/504 22/18722 0.451574433847873 0.628936621848748 PDGFRB 1 GO:0099563 modification of synaptic structure 1/504 22/18722 0.451574433847873 0.628936621848748 ITSN1 1 GO:0106030 neuron projection fasciculation 1/504 22/18722 0.451574433847873 0.628936621848748 SEMA5A 1 GO:1900120 regulation of receptor binding 1/504 22/18722 0.451574433847873 0.628936621848748 B2M 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/504 22/18722 0.451574433847873 0.628936621848748 STAT3 1 GO:1901032 negative regulation of response to reactive oxygen species 1/504 22/18722 0.451574433847873 0.628936621848748 HGF 1 GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/504 22/18722 0.451574433847873 0.628936621848748 AGTR1 1 GO:2000773 negative regulation of cellular senescence 1/504 22/18722 0.451574433847873 0.628936621848748 AKT3 1 GO:0032465 regulation of cytokinesis 3/504 92/18722 0.452148058782121 0.629530353592702 MAP9/CALM2/SVIL 3 GO:0033865 nucleoside bisphosphate metabolic process 4/504 128/18722 0.453260058101956 0.630462313889862 ENPP1/PAPSS2/ELOVL5/ACLY 4 GO:0033875 ribonucleoside bisphosphate metabolic process 4/504 128/18722 0.453260058101956 0.630462313889862 ENPP1/PAPSS2/ELOVL5/ACLY 4 GO:0034032 purine nucleoside bisphosphate metabolic process 4/504 128/18722 0.453260058101956 0.630462313889862 ENPP1/PAPSS2/ELOVL5/ACLY 4 GO:0034249 negative regulation of cellular amide metabolic process 8/504 273/18722 0.454226584570809 0.631601105067058 IGFBP5/ZFP36L1/EIF4EBP1/ZFP36/ROCK2/STAT3/TNRC6B/EIF4EBP2 8 GO:0009896 positive regulation of catabolic process 14/504 492/18722 0.454522217095213 0.631806582188629 DCN/FOXO1/MTDH/GPC3/CD81/CAV1/KCNQ1OT1/ZFP36L1/ZFP36/ROCK2/MSN/ADAM9/PTEN/TNRC6B 14 GO:0006611 protein export from nucleus 2/504 57/18722 0.456308825609248 0.632438407988426 GAS6/IFI27 2 GO:0006695 cholesterol biosynthetic process 2/504 57/18722 0.456308825609248 0.632438407988426 CYB5R3/ACLY 2 GO:0006754 ATP biosynthetic process 2/504 57/18722 0.456308825609248 0.632438407988426 TMSB4X/STAT3 2 GO:0030219 megakaryocyte differentiation 2/504 57/18722 0.456308825609248 0.632438407988426 MEIS1/MEF2C 2 GO:0050879 multicellular organismal movement 2/504 57/18722 0.456308825609248 0.632438407988426 HIPK2/NR4A1 2 GO:0050881 musculoskeletal movement 2/504 57/18722 0.456308825609248 0.632438407988426 HIPK2/NR4A1 2 GO:0051155 positive regulation of striated muscle cell differentiation 2/504 57/18722 0.456308825609248 0.632438407988426 MYOCD/MEF2C 2 GO:0051785 positive regulation of nuclear division 2/504 57/18722 0.456308825609248 0.632438407988426 PDGFRB/IGF2 2 GO:1902653 secondary alcohol biosynthetic process 2/504 57/18722 0.456308825609248 0.632438407988426 CYB5R3/ACLY 2 GO:0032635 interleukin-6 production 5/504 165/18722 0.458324779950985 0.634820675763553 SPON2/HGF/GAS6/XBP1/STAT3 5 GO:0032675 regulation of interleukin-6 production 5/504 165/18722 0.458324779950985 0.634820675763553 SPON2/HGF/GAS6/XBP1/STAT3 5 GO:0007589 body fluid secretion 3/504 93/18722 0.45917191416777 0.635002249316684 CAV1/NCOR2/XBP1 3 GO:0019217 regulation of fatty acid metabolic process 3/504 93/18722 0.45917191416777 0.635002249316684 CAV1/LPGAT1/ELOVL5 3 GO:0032755 positive regulation of interleukin-6 production 3/504 93/18722 0.45917191416777 0.635002249316684 SPON2/XBP1/STAT3 3 GO:0097306 cellular response to alcohol 3/504 93/18722 0.45917191416777 0.635002249316684 ADCY3/PTEN/AHR 3 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 4/504 129/18722 0.459198911862521 0.635002249316684 DLC1/UACA/HIP1/GSN 4 GO:0016051 carbohydrate biosynthetic process 6/504 202/18722 0.461820472082176 0.635439150761185 NNMT/ENPP1/EXT1/DYRK2/IGF2/ATF3 6 GO:1903046 meiotic cell cycle process 6/504 202/18722 0.461820472082176 0.635439150761185 PDE3A/HSPA2/MYH9/P3H4/PRKAR1A/ATRX 6 GO:0030307 positive regulation of cell growth 5/504 166/18722 0.463550473810626 0.635439150761185 MAP1B/SEMA5A/TGFB2/MACF1/BMPR2 5 GO:0043112 receptor metabolic process 5/504 166/18722 0.463550473810626 0.635439150761185 RAMP1/CD81/ITGB1/CAV1/MKLN1 5 GO:0061013 regulation of mRNA catabolic process 5/504 166/18722 0.463550473810626 0.635439150761185 VIM/ZFP36L1/ZFP36/ROCK2/TNRC6B 5 GO:0070588 calcium ion transmembrane transport 9/504 312/18722 0.464169065193898 0.635439150761185 THY1/GAS6/SLC8A1/HSPA2/ATP2B4/PKD2/CALM2/VMP1/AHNAK 9 GO:0007098 centrosome cycle 4/504 130/18722 0.465115657651216 0.635439150761185 PKD2/MAP9/ROCK2/PPP1R12A 4 GO:0015918 sterol transport 4/504 130/18722 0.465115657651216 0.635439150761185 LIPG/CAV1/LIMA1/TSPO 4 GO:0030534 adult behavior 4/504 130/18722 0.465115657651216 0.635439150761185 CCND2/EPS8/HIPK2/PTEN 4 GO:0006826 iron ion transport 2/504 58/18722 0.465285540534065 0.635439150761185 CYBRD1/B2M 2 GO:0010574 regulation of vascular endothelial growth factor production 2/504 58/18722 0.465285540534065 0.635439150761185 SULF2/IL6ST 2 GO:0042743 hydrogen peroxide metabolic process 2/504 58/18722 0.465285540534065 0.635439150761185 PXDN/STAT3 2 GO:0032091 negative regulation of protein binding 3/504 94/18722 0.466157092004104 0.635439150761185 ACTB/CAV1/B2M 3 GO:1990830 cellular response to leukemia inhibitory factor 3/504 94/18722 0.466157092004104 0.635439150761185 EPS8/ARID5B/CTBP2 3 GO:0002082 regulation of oxidative phosphorylation 1/504 23/18722 0.466355529320636 0.635439150761185 COX7A1 1 GO:0002363 alpha-beta T cell lineage commitment 1/504 23/18722 0.466355529320636 0.635439150761185 STAT3 1 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1/504 23/18722 0.466355529320636 0.635439150761185 AGTR1 1 GO:0003323 type B pancreatic cell development 1/504 23/18722 0.466355529320636 0.635439150761185 CLOCK 1 GO:0006541 glutamine metabolic process 1/504 23/18722 0.466355529320636 0.635439150761185 GLS 1 GO:0007130 synaptonemal complex assembly 1/504 23/18722 0.466355529320636 0.635439150761185 P3H4 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/504 23/18722 0.466355529320636 0.635439150761185 GAS6 1 GO:0021884 forebrain neuron development 1/504 23/18722 0.466355529320636 0.635439150761185 ZMIZ1 1 GO:0030194 positive regulation of blood coagulation 1/504 23/18722 0.466355529320636 0.635439150761185 THBS1 1 GO:0030539 male genitalia development 1/504 23/18722 0.466355529320636 0.635439150761185 PDGFRA 1 GO:0031280 negative regulation of cyclase activity 1/504 23/18722 0.466355529320636 0.635439150761185 EDNRB 1 GO:0033081 regulation of T cell differentiation in thymus 1/504 23/18722 0.466355529320636 0.635439150761185 SOS1 1 GO:0034105 positive regulation of tissue remodeling 1/504 23/18722 0.466355529320636 0.635439150761185 ROCK2 1 GO:0035929 steroid hormone secretion 1/504 23/18722 0.466355529320636 0.635439150761185 AGTR1 1 GO:0036119 response to platelet-derived growth factor 1/504 23/18722 0.466355529320636 0.635439150761185 PDGFRB 1 GO:0036303 lymph vessel morphogenesis 1/504 23/18722 0.466355529320636 0.635439150761185 BMPR2 1 GO:0042438 melanin biosynthetic process 1/504 23/18722 0.466355529320636 0.635439150761185 ZEB2 1 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 1/504 23/18722 0.466355529320636 0.635439150761185 STAT3 1 GO:0043931 ossification involved in bone maturation 1/504 23/18722 0.466355529320636 0.635439150761185 EXT1 1 GO:0045980 negative regulation of nucleotide metabolic process 1/504 23/18722 0.466355529320636 0.635439150761185 STAT3 1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 1/504 23/18722 0.466355529320636 0.635439150761185 UGDH 1 GO:0051349 positive regulation of lyase activity 1/504 23/18722 0.466355529320636 0.635439150761185 TIMP2 1 GO:0051457 maintenance of protein location in nucleus 1/504 23/18722 0.466355529320636 0.635439150761185 SYNE1 1 GO:0051590 positive regulation of neurotransmitter transport 1/504 23/18722 0.466355529320636 0.635439150761185 ITGB1 1 GO:0060384 innervation 1/504 23/18722 0.466355529320636 0.635439150761185 SULF2 1 GO:0060487 lung epithelial cell differentiation 1/504 23/18722 0.466355529320636 0.635439150761185 NFIB 1 GO:0060547 negative regulation of necrotic cell death 1/504 23/18722 0.466355529320636 0.635439150761185 CAV1 1 GO:0060575 intestinal epithelial cell differentiation 1/504 23/18722 0.466355529320636 0.635439150761185 IL6ST 1 GO:0071305 cellular response to vitamin D 1/504 23/18722 0.466355529320636 0.635439150761185 KANK2 1 GO:1900048 positive regulation of hemostasis 1/504 23/18722 0.466355529320636 0.635439150761185 THBS1 1 GO:1900273 positive regulation of long-term synaptic potentiation 1/504 23/18722 0.466355529320636 0.635439150761185 NPTN 1 GO:1904666 regulation of ubiquitin protein ligase activity 1/504 23/18722 0.466355529320636 0.635439150761185 PTEN 1 GO:0055088 lipid homeostasis 5/504 167/18722 0.468761200223003 0.638513423191869 RBP1/LIPG/CAV1/LIMA1/XBP1 5 GO:0018022 peptidyl-lysine methylation 4/504 131/18722 0.471009289585524 0.641166834787813 NNMT/KMT2E/ATRX/KMT2A 4 GO:0019827 stem cell population maintenance 4/504 131/18722 0.471009289585524 0.641166834787813 JAG1/SOX4/NOTCH2/STAT3 4 GO:0036473 cell death in response to oxidative stress 3/504 95/18722 0.473102171146353 0.643605723434691 HGF/HSPB1/NCOA7 3 GO:0048709 oligodendrocyte differentiation 3/504 95/18722 0.473102171146353 0.643605723434691 MDK/SOX6/PTEN 3 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 5/504 168/18722 0.473956226222316 0.644038705074592 MEF2C/CD81/IL1R1/B2M/AHR 5 GO:0001836 release of cytochrome c from mitochondria 2/504 59/18722 0.474174061821827 0.644038705074592 HGF/JUN 2 GO:0033013 tetrapyrrole metabolic process 2/504 59/18722 0.474174061821827 0.644038705074592 TSPO/NFE2L1 2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2/504 59/18722 0.474174061821827 0.644038705074592 THY1/CAV1 2 GO:0071806 protein transmembrane transport 2/504 59/18722 0.474174061821827 0.644038705074592 TOMM7/SEC62 2 GO:0018105 peptidyl-serine phosphorylation 9/504 315/18722 0.475559298755154 0.645714929641174 HGF/GAS6/DYRK2/ATP2B4/CAV1/HIPK2/ROCK2/PTEN/AKT3 9 GO:0002790 peptide secretion 7/504 242/18722 0.477396852306189 0.647195278641894 CAMK2N1/LTBP4/SOX4/MAP4K4/ITSN1/CLOCK/RAB11FIP2 7 GO:0018394 peptidyl-lysine acetylation 5/504 169/18722 0.479134834957713 0.647195278641894 MYOCD/SOX4/CLOCK/KMT2A/EPC1 5 GO:0001702 gastrulation with mouth forming second 1/504 24/18722 0.480739015775655 0.647195278641894 UGDH 1 GO:0001783 B cell apoptotic process 1/504 24/18722 0.480739015775655 0.647195278641894 PTEN 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/504 24/18722 0.480739015775655 0.647195278641894 EXT1 1 GO:0006582 melanin metabolic process 1/504 24/18722 0.480739015775655 0.647195278641894 ZEB2 1 GO:0010226 response to lithium ion 1/504 24/18722 0.480739015775655 0.647195278641894 IGFBP2 1 GO:0031639 plasminogen activation 1/504 24/18722 0.480739015775655 0.647195278641894 THBS1 1 GO:0032528 microvillus organization 1/504 24/18722 0.480739015775655 0.647195278641894 RAP2A 1 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 1/504 24/18722 0.480739015775655 0.647195278641894 ATF3 1 GO:0038095 Fc-epsilon receptor signaling pathway 1/504 24/18722 0.480739015775655 0.647195278641894 SOS1 1 GO:0050687 negative regulation of defense response to virus 1/504 24/18722 0.480739015775655 0.647195278641894 HTRA1 1 GO:0050820 positive regulation of coagulation 1/504 24/18722 0.480739015775655 0.647195278641894 THBS1 1 GO:0051570 regulation of histone H3-K9 methylation 1/504 24/18722 0.480739015775655 0.647195278641894 ATRX 1 GO:0051923 sulfation 1/504 24/18722 0.480739015775655 0.647195278641894 EXT1 1 GO:0060479 lung cell differentiation 1/504 24/18722 0.480739015775655 0.647195278641894 NFIB 1 GO:0060571 morphogenesis of an epithelial fold 1/504 24/18722 0.480739015775655 0.647195278641894 WNT2 1 GO:0070841 inclusion body assembly 1/504 24/18722 0.480739015775655 0.647195278641894 HSPA2 1 GO:0070935 3'-UTR-mediated mRNA stabilization 1/504 24/18722 0.480739015775655 0.647195278641894 ZFP36 1 GO:0071577 zinc ion transmembrane transport 1/504 24/18722 0.480739015775655 0.647195278641894 SLC39A6 1 GO:0071676 negative regulation of mononuclear cell migration 1/504 24/18722 0.480739015775655 0.647195278641894 APOD 1 GO:0090023 positive regulation of neutrophil chemotaxis 1/504 24/18722 0.480739015775655 0.647195278641894 MDK 1 GO:0090343 positive regulation of cell aging 1/504 24/18722 0.480739015775655 0.647195278641894 B2M 1 GO:0120255 olefinic compound biosynthetic process 1/504 24/18722 0.480739015775655 0.647195278641894 EGR1 1 GO:1903077 negative regulation of protein localization to plasma membrane 1/504 24/18722 0.480739015775655 0.647195278641894 RHOQ 1 GO:2000310 regulation of NMDA receptor activity 1/504 24/18722 0.480739015775655 0.647195278641894 MEF2C 1 GO:2000679 positive regulation of transcription regulatory region DNA binding 1/504 24/18722 0.480739015775655 0.647195278641894 HAND2 1 GO:0043543 protein acylation 7/504 243/18722 0.481711590791736 0.648300355103335 MYOCD/FOXO1/SOX4/CLOCK/TAOK1/KMT2A/EPC1 7 GO:0009620 response to fungus 2/504 60/18722 0.482972626630415 0.649792207878102 SPON2/RARRES2 2 GO:0010506 regulation of autophagy 9/504 317/18722 0.483124232255729 0.649792207878102 DCN/HGF/FOXO1/MTDH/TSPO/QSOX1/IFI16/HSPB1/STAT3 9 GO:0043487 regulation of RNA stability 5/504 170/18722 0.484296325709482 0.651163687777413 VIM/ZFP36L1/ZFP36/ROCK2/TNRC6B 5 GO:0016064 immunoglobulin mediated immune response 6/504 207/18722 0.485313775955548 0.652326443742704 C1R/C1S/CD81/SERPING1/B2M/NBN 6 GO:0006721 terpenoid metabolic process 3/504 97/18722 0.486866654219039 0.654207928766651 RBP1/RARRES2/DHRS3 3 GO:0098727 maintenance of cell number 4/504 134/18722 0.488541878163942 0.656252576357914 JAG1/SOX4/NOTCH2/STAT3 4 GO:0006836 neurotransmitter transport 6/504 208/18722 0.489975187746663 0.657544349190866 MEF2C/ITGB1/SLC38A2/PREPL/CTBP2/NR4A1 6 GO:1901215 negative regulation of neuron death 6/504 208/18722 0.489975187746663 0.657544349190866 AXL/MEF2C/MDK/HIPK2/STAT3/NCOA7 6 GO:0040014 regulation of multicellular organism growth 2/504 61/18722 0.491679630453499 0.657544349190866 IGF2/STAT3 2 GO:0043030 regulation of macrophage activation 2/504 61/18722 0.491679630453499 0.657544349190866 THBS1/PJA2 2 GO:0060997 dendritic spine morphogenesis 2/504 61/18722 0.491679630453499 0.657544349190866 PDLIM5/PTEN 2 GO:2000401 regulation of lymphocyte migration 2/504 61/18722 0.491679630453499 0.657544349190866 APOD/MSN 2 GO:0006417 regulation of translation 13/504 468/18722 0.49391733935953 0.657544349190866 IGFBP5/THBS1/VIM/SOX4/ZFP36L1/EIF4G3/HSPB1/EIF4EBP1/ZFP36/ROCK2/STAT3/TNRC6B/EIF4EBP2 13 GO:0009416 response to light stimulus 9/504 320/18722 0.494422666502631 0.657544349190866 TIMP1/MMP2/CRIP1/ITGB1/EXT1/CLOCK/POLK/PIK3R1/NPTN 9 GO:0051402 neuron apoptotic process 7/504 246/18722 0.494595589485475 0.657544349190866 ITGA1/AXL/TGFB2/MEF2C/MDK/HIPK2/JUN 7 GO:0001964 startle response 1/504 25/18722 0.494735568136821 0.657544349190866 PTEN 1 GO:0006312 mitotic recombination 1/504 25/18722 0.494735568136821 0.657544349190866 SMC6 1 GO:0010560 positive regulation of glycoprotein biosynthetic process 1/504 25/18722 0.494735568136821 0.657544349190866 RAMP1 1 GO:0010842 retina layer formation 1/504 25/18722 0.494735568136821 0.657544349190866 HIPK2 1 GO:0010996 response to auditory stimulus 1/504 25/18722 0.494735568136821 0.657544349190866 MDK 1 GO:0015874 norepinephrine transport 1/504 25/18722 0.494735568136821 0.657544349190866 ACTB 1 GO:0032104 regulation of response to extracellular stimulus 1/504 25/18722 0.494735568136821 0.657544349190866 KANK2 1 GO:0032107 regulation of response to nutrient levels 1/504 25/18722 0.494735568136821 0.657544349190866 KANK2 1 GO:0035336 long-chain fatty-acyl-CoA metabolic process 1/504 25/18722 0.494735568136821 0.657544349190866 ELOVL5 1 GO:0035902 response to immobilization stress 1/504 25/18722 0.494735568136821 0.657544349190866 SLC8A1 1 GO:0044550 secondary metabolite biosynthetic process 1/504 25/18722 0.494735568136821 0.657544349190866 ZEB2 1 GO:0045109 intermediate filament organization 1/504 25/18722 0.494735568136821 0.657544349190866 VIM 1 GO:0045324 late endosome to vacuole transport 1/504 25/18722 0.494735568136821 0.657544349190866 TMEM50B 1 GO:0046039 GTP metabolic process 1/504 25/18722 0.494735568136821 0.657544349190866 RHOQ 1 GO:0046949 fatty-acyl-CoA biosynthetic process 1/504 25/18722 0.494735568136821 0.657544349190866 ELOVL5 1 GO:0060706 cell differentiation involved in embryonic placenta development 1/504 25/18722 0.494735568136821 0.657544349190866 NR2F2 1 GO:0086013 membrane repolarization during cardiac muscle cell action potential 1/504 25/18722 0.494735568136821 0.657544349190866 FLNA 1 GO:0090312 positive regulation of protein deacetylation 1/504 25/18722 0.494735568136821 0.657544349190866 NNMT 1 GO:0099560 synaptic membrane adhesion 1/504 25/18722 0.494735568136821 0.657544349190866 SPARCL1 1 GO:1900078 positive regulation of cellular response to insulin stimulus 1/504 25/18722 0.494735568136821 0.657544349190866 IGF2 1 GO:1902993 positive regulation of amyloid precursor protein catabolic process 1/504 25/18722 0.494735568136821 0.657544349190866 ROCK2 1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/504 25/18722 0.494735568136821 0.657544349190866 THBS1 1 GO:1903959 regulation of anion transmembrane transport 1/504 25/18722 0.494735568136821 0.657544349190866 ITGB1 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/504 25/18722 0.494735568136821 0.657544349190866 MEF2C 1 GO:2000311 regulation of AMPA receptor activity 1/504 25/18722 0.494735568136821 0.657544349190866 MEF2C 1 GO:0019724 B cell mediated immunity 6/504 210/18722 0.499256516910614 0.662262332427244 C1R/C1S/CD81/SERPING1/B2M/NBN 6 GO:0031396 regulation of protein ubiquitination 6/504 210/18722 0.499256516910614 0.662262332427244 NXN/SOX4/CAV1/TSPO/ISG15/PTEN 6 GO:0099024 plasma membrane invagination 4/504 136/18722 0.500097559256987 0.662262332427244 THBS1/MFGE8/MYH9/GSN 4 GO:0051051 negative regulation of transport 13/504 470/18722 0.500139116400137 0.662262332427244 THBS1/CRYAB/MAP1B/APOD/ENPP1/PKIG/CAV1/CNN2/PKD2/CALM2/MAP4K4/PTEN/PEA15 13 GO:0002260 lymphocyte homeostasis 2/504 62/18722 0.500293619903713 0.662262332427244 MEF2C/SOS1 2 GO:0010573 vascular endothelial growth factor production 2/504 62/18722 0.500293619903713 0.662262332427244 SULF2/IL6ST 2 GO:0032615 interleukin-12 production 2/504 62/18722 0.500293619903713 0.662262332427244 THBS1/MDK 2 GO:0032655 regulation of interleukin-12 production 2/504 62/18722 0.500293619903713 0.662262332427244 THBS1/MDK 2 GO:0060113 inner ear receptor cell differentiation 2/504 62/18722 0.500293619903713 0.662262332427244 CTHRC1/JAG1 2 GO:0070265 necrotic cell death 2/504 62/18722 0.500293619903713 0.662262332427244 CAV1/TSPO 2 GO:0000045 autophagosome assembly 3/504 99/18722 0.500455200423021 0.662262332427244 SYNPO2/VMP1/MAP1LC3A 3 GO:0007631 feeding behavior 3/504 99/18722 0.500455200423021 0.662262332427244 HAND2/GLS/STAT3 3 GO:0021510 spinal cord development 3/504 99/18722 0.500455200423021 0.662262332427244 SOX4/SOX6/PKD2 3 GO:0042100 B cell proliferation 3/504 99/18722 0.500455200423021 0.662262332427244 MEF2C/CD81/AHR 3 GO:0042180 cellular ketone metabolic process 6/504 211/18722 0.503875418568753 0.665472532231997 ATP2B4/CAV1/EGR1/LPGAT1/NCOR2/ELOVL5 6 GO:0008203 cholesterol metabolic process 4/504 137/18722 0.505832998758323 0.665472532231997 LIMA1/CYB5R3/ACLY/NFE2L1 4 GO:0050714 positive regulation of protein secretion 4/504 137/18722 0.505832998758323 0.665472532231997 CAMK2N1/TGFB2/SOX4/ADAM9 4 GO:0006641 triglyceride metabolic process 3/504 100/18722 0.507180575765806 0.665472532231997 LIPG/CAV1/LPGAT1 3 GO:0044728 DNA methylation or demethylation 3/504 100/18722 0.507180575765806 0.665472532231997 KMT2E/ATRX/KMT2A 3 GO:0051588 regulation of neurotransmitter transport 3/504 100/18722 0.507180575765806 0.665472532231997 MEF2C/ITGB1/PREPL 3 GO:0001556 oocyte maturation 1/504 26/18722 0.50835557528551 0.665472532231997 PDE3A 1 GO:0002407 dendritic cell chemotaxis 1/504 26/18722 0.50835557528551 0.665472532231997 GAS6 1 GO:0002418 immune response to tumor cell 1/504 26/18722 0.50835557528551 0.665472532231997 AHR 1 GO:0002710 negative regulation of T cell mediated immunity 1/504 26/18722 0.50835557528551 0.665472532231997 AHR 1 GO:0006517 protein deglycosylation 1/504 26/18722 0.50835557528551 0.665472532231997 MAN2A1 1 GO:0009435 NAD biosynthetic process 1/504 26/18722 0.50835557528551 0.665472532231997 NNMT 1 GO:0010875 positive regulation of cholesterol efflux 1/504 26/18722 0.50835557528551 0.665472532231997 CAV1 1 GO:0018027 peptidyl-lysine dimethylation 1/504 26/18722 0.50835557528551 0.665472532231997 KMT2A 1 GO:0019883 antigen processing and presentation of endogenous antigen 1/504 26/18722 0.50835557528551 0.665472532231997 B2M 1 GO:0032515 negative regulation of phosphoprotein phosphatase activity 1/504 26/18722 0.50835557528551 0.665472532231997 ROCK2 1 GO:0032682 negative regulation of chemokine production 1/504 26/18722 0.50835557528551 0.665472532231997 APOD 1 GO:0033522 histone H2A ubiquitination 1/504 26/18722 0.50835557528551 0.665472532231997 PCGF5 1 GO:0042537 benzene-containing compound metabolic process 1/504 26/18722 0.50835557528551 0.665472532231997 GSTM3 1 GO:0043501 skeletal muscle adaptation 1/504 26/18722 0.50835557528551 0.665472532231997 IGFBP5 1 GO:0045672 positive regulation of osteoclast differentiation 1/504 26/18722 0.50835557528551 0.665472532231997 NOTCH2 1 GO:0046697 decidualization 1/504 26/18722 0.50835557528551 0.665472532231997 CITED2 1 GO:0048843 negative regulation of axon extension involved in axon guidance 1/504 26/18722 0.50835557528551 0.665472532231997 SEMA5A 1 GO:0051350 negative regulation of lyase activity 1/504 26/18722 0.50835557528551 0.665472532231997 EDNRB 1 GO:0060219 camera-type eye photoreceptor cell differentiation 1/504 26/18722 0.50835557528551 0.665472532231997 THY1 1 GO:0060544 regulation of necroptotic process 1/504 26/18722 0.50835557528551 0.665472532231997 CAV1 1 GO:0070977 bone maturation 1/504 26/18722 0.50835557528551 0.665472532231997 EXT1 1 GO:0097186 amelogenesis 1/504 26/18722 0.50835557528551 0.665472532231997 FOXO1 1 GO:0099637 neurotransmitter receptor transport 1/504 26/18722 0.50835557528551 0.665472532231997 HIP1 1 GO:1900017 positive regulation of cytokine production involved in inflammatory response 1/504 26/18722 0.50835557528551 0.665472532231997 STAT3 1 GO:1902186 regulation of viral release from host cell 1/504 26/18722 0.50835557528551 0.665472532231997 CAV2 1 GO:1904353 regulation of telomere capping 1/504 26/18722 0.50835557528551 0.665472532231997 NBN 1 GO:1904376 negative regulation of protein localization to cell periphery 1/504 26/18722 0.50835557528551 0.665472532231997 RHOQ 1 GO:2000050 regulation of non-canonical Wnt signaling pathway 1/504 26/18722 0.50835557528551 0.665472532231997 GPC3 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/504 26/18722 0.50835557528551 0.665472532231997 MEF2C 1 GO:0070997 neuron death 10/504 361/18722 0.508487670895734 0.665472532231997 ITGA1/AXL/TGFB2/MEF2C/MDK/EGR1/HIPK2/JUN/STAT3/NCOA7 10 GO:0099601 regulation of neurotransmitter receptor activity 2/504 63/18722 0.50881328576836 0.665694785697551 MEF2C/DLGAP4 2 GO:0055076 transition metal ion homeostasis 4/504 138/18722 0.511539086159609 0.669056172378332 MT1E/CYBRD1/SLC39A6/B2M 4 GO:0001505 regulation of neurotransmitter levels 6/504 213/18722 0.513067233286737 0.670849537280976 MEF2C/ITGB1/PREPL/MAOA/CTBP2/NR4A1 6 GO:0006476 protein deacetylation 3/504 101/18722 0.513858573842834 0.671473298480253 NNMT/FLNA/HDAC7 3 GO:0051963 regulation of synapse assembly 3/504 101/18722 0.513858573842834 0.671473298480253 FARP1/PDLIM5/MEF2C 3 GO:0016126 sterol biosynthetic process 2/504 64/18722 0.517237456328253 0.675269065350023 CYB5R3/ACLY 2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 2/504 64/18722 0.517237456328253 0.675269065350023 CAMK2N1/MAP4K4 2 GO:1900076 regulation of cellular response to insulin stimulus 2/504 64/18722 0.517237456328253 0.675269065350023 ENPP1/IGF2 2 GO:0098739 import across plasma membrane 5/504 177/18722 0.519891982190571 0.675404814595946 THBS1/ITGB1/SLC8A1/ATP2B4/SLC39A6 5 GO:0035710 CD4-positive, alpha-beta T cell activation 3/504 102/18722 0.520488178975699 0.675404814595946 TWSG1/CD81/STAT3 3 GO:1902106 negative regulation of leukocyte differentiation 3/504 102/18722 0.520488178975699 0.675404814595946 MDK/FBN1/PIK3R1 3 GO:0001835 blastocyst hatching 1/504 27/18722 0.521609147710419 0.675404814595946 CMTM3 1 GO:0002719 negative regulation of cytokine production involved in immune response 1/504 27/18722 0.521609147710419 0.675404814595946 TGFB2 1 GO:0002825 regulation of T-helper 1 type immune response 1/504 27/18722 0.521609147710419 0.675404814595946 IL1R1 1 GO:0007628 adult walking behavior 1/504 27/18722 0.521609147710419 0.675404814595946 HIPK2 1 GO:0009651 response to salt stress 1/504 27/18722 0.521609147710419 0.675404814595946 ZFP36L1 1 GO:0015813 L-glutamate transmembrane transport 1/504 27/18722 0.521609147710419 0.675404814595946 ITGB1 1 GO:0032781 positive regulation of ATPase activity 1/504 27/18722 0.521609147710419 0.675404814595946 TPM1 1 GO:0033688 regulation of osteoblast proliferation 1/504 27/18722 0.521609147710419 0.675404814595946 CTHRC1 1 GO:0035116 embryonic hindlimb morphogenesis 1/504 27/18722 0.521609147710419 0.675404814595946 GPC3 1 GO:0035188 hatching 1/504 27/18722 0.521609147710419 0.675404814595946 CMTM3 1 GO:0042402 cellular biogenic amine catabolic process 1/504 27/18722 0.521609147710419 0.675404814595946 MAOA 1 GO:0042403 thyroid hormone metabolic process 1/504 27/18722 0.521609147710419 0.675404814595946 CTSK 1 GO:0046337 phosphatidylethanolamine metabolic process 1/504 27/18722 0.521609147710419 0.675404814595946 PLA2G2A 1 GO:0048520 positive regulation of behavior 1/504 27/18722 0.521609147710419 0.675404814595946 MEF2C 1 GO:0048873 homeostasis of number of cells within a tissue 1/504 27/18722 0.521609147710419 0.675404814595946 AKT3 1 GO:0060333 interferon-gamma-mediated signaling pathway 1/504 27/18722 0.521609147710419 0.675404814595946 JAK1 1 GO:0060512 prostate gland morphogenesis 1/504 27/18722 0.521609147710419 0.675404814595946 CRIP1 1 GO:0070861 regulation of protein exit from endoplasmic reticulum 1/504 27/18722 0.521609147710419 0.675404814595946 CD81 1 GO:0071624 positive regulation of granulocyte chemotaxis 1/504 27/18722 0.521609147710419 0.675404814595946 MDK 1 GO:0071684 organism emergence from protective structure 1/504 27/18722 0.521609147710419 0.675404814595946 CMTM3 1 GO:0098901 regulation of cardiac muscle cell action potential 1/504 27/18722 0.521609147710419 0.675404814595946 CAV1 1 GO:1903203 regulation of oxidative stress-induced neuron death 1/504 27/18722 0.521609147710419 0.675404814595946 NCOA7 1 GO:1903205 regulation of hydrogen peroxide-induced cell death 1/504 27/18722 0.521609147710419 0.675404814595946 HGF 1 GO:2000463 positive regulation of excitatory postsynaptic potential 1/504 27/18722 0.521609147710419 0.675404814595946 PTEN 1 GO:0009266 response to temperature stimulus 5/504 178/18722 0.524893235925013 0.679451316906265 IGFBP7/THBS1/TGFB1I1/FOXO1/HSPA2 5 GO:0015909 long-chain fatty acid transport 2/504 65/18722 0.525565090930599 0.679703278918417 PLA2G2A/THBS1 2 GO:0045453 bone resorption 2/504 65/18722 0.525565090930599 0.679703278918417 CTSK/EXT1 2 GO:0090307 mitotic spindle assembly 2/504 65/18722 0.525565090930599 0.679703278918417 FLNA/MAP9 2 GO:0014013 regulation of gliogenesis 3/504 103/18722 0.527068428799031 0.680823275773356 MDK/IL6ST/TSPO 3 GO:0030593 neutrophil chemotaxis 3/504 103/18722 0.527068428799031 0.680823275773356 ITGA1/TGFB2/MDK 3 GO:0090277 positive regulation of peptide hormone secretion 3/504 103/18722 0.527068428799031 0.680823275773356 CAMK2N1/SOX4/ITSN1 3 GO:1905037 autophagosome organization 3/504 103/18722 0.527068428799031 0.680823275773356 SYNPO2/VMP1/MAP1LC3A 3 GO:0016571 histone methylation 4/504 141/18722 0.528473581296256 0.682432037739166 NNMT/KMT2E/ATRX/KMT2A 4 GO:0009150 purine ribonucleotide metabolic process 10/504 368/18722 0.533018911169497 0.683611096056588 GUCY1A2/PDE8B/ENPP1/ADCY3/PAPSS2/TMSB4X/RHOQ/ELOVL5/STAT3/ACLY 10 GO:0071692 protein localization to extracellular region 10/504 368/18722 0.533018911169497 0.683611096056588 LTBP2/CAMK2N1/TGFB2/SOX4/LTBP1/FBN1/MAP4K4/CLOCK/ADAM9/RAB11FIP2 10 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 3/504 104/18722 0.533598413089969 0.683611096056588 AGTR1/LPAR1/EDNRB 3 GO:0032715 negative regulation of interleukin-6 production 2/504 66/18722 0.533795273807137 0.683611096056588 HGF/GAS6 2 GO:0042446 hormone biosynthetic process 2/504 66/18722 0.533795273807137 0.683611096056588 EGR1/TSPO 2 GO:0050766 positive regulation of phagocytosis 2/504 66/18722 0.533795273807137 0.683611096056588 MFGE8/GAS6 2 GO:0050918 positive chemotaxis 2/504 66/18722 0.533795273807137 0.683611096056588 SEMA5A/HGF 2 GO:0050922 negative regulation of chemotaxis 2/504 66/18722 0.533795273807137 0.683611096056588 THBS1/SEMA5A 2 GO:0000423 mitophagy 1/504 28/18722 0.534506124953209 0.683611096056588 TOMM7 1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1/504 28/18722 0.534506124953209 0.683611096056588 B2M 1 GO:0006516 glycoprotein catabolic process 1/504 28/18722 0.534506124953209 0.683611096056588 ADAMTS9 1 GO:0006829 zinc ion transport 1/504 28/18722 0.534506124953209 0.683611096056588 SLC39A6 1 GO:0007064 mitotic sister chromatid cohesion 1/504 28/18722 0.534506124953209 0.683611096056588 ATRX 1 GO:0007141 male meiosis I 1/504 28/18722 0.534506124953209 0.683611096056588 HSPA2 1 GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1/504 28/18722 0.534506124953209 0.683611096056588 PLPP1 1 GO:0007271 synaptic transmission, cholinergic 1/504 28/18722 0.534506124953209 0.683611096056588 LAMA2 1 GO:0008299 isoprenoid biosynthetic process 1/504 28/18722 0.534506124953209 0.683611096056588 RBP1 1 GO:0010460 positive regulation of heart rate 1/504 28/18722 0.534506124953209 0.683611096056588 TPM1 1 GO:0019098 reproductive behavior 1/504 28/18722 0.534506124953209 0.683611096056588 PTEN 1 GO:0031440 regulation of mRNA 3'-end processing 1/504 28/18722 0.534506124953209 0.683611096056588 ZFP36L1 1 GO:0032438 melanosome organization 1/504 28/18722 0.534506124953209 0.683611096056588 ZEB2 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/504 28/18722 0.534506124953209 0.683611096056588 ITGA1 1 GO:0044331 cell-cell adhesion mediated by cadherin 1/504 28/18722 0.534506124953209 0.683611096056588 TJP1 1 GO:0045589 regulation of regulatory T cell differentiation 1/504 28/18722 0.534506124953209 0.683611096056588 MDK 1 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 1/504 28/18722 0.534506124953209 0.683611096056588 CAV1 1 GO:0051503 adenine nucleotide transport 1/504 28/18722 0.534506124953209 0.683611096056588 SLC25A24 1 GO:0060259 regulation of feeding behavior 1/504 28/18722 0.534506124953209 0.683611096056588 STAT3 1 GO:0060765 regulation of androgen receptor signaling pathway 1/504 28/18722 0.534506124953209 0.683611096056588 NCOR2 1 GO:0090659 walking behavior 1/504 28/18722 0.534506124953209 0.683611096056588 HIPK2 1 GO:0099623 regulation of cardiac muscle cell membrane repolarization 1/504 28/18722 0.534506124953209 0.683611096056588 FLNA 1 GO:1903020 positive regulation of glycoprotein metabolic process 1/504 28/18722 0.534506124953209 0.683611096056588 RAMP1 1 GO:1903649 regulation of cytoplasmic transport 1/504 28/18722 0.534506124953209 0.683611096056588 MSN 1 GO:0007033 vacuole organization 5/504 180/18722 0.534827099605513 0.683816934953428 SYNPO2/EXT1/VMP1/MAP1LC3A/MAN2A1 5 GO:0042445 hormone metabolic process 6/504 218/18722 0.535756711354455 0.68480060652635 RBP1/PDGFRA/CTSK/EGR1/TSPO/DHRS3 6 GO:0034976 response to endoplasmic reticulum stress 7/504 256/18722 0.53676627977772 0.685885859297308 THBS1/CAV1/HSP90B1/JUN/XBP1/ATF3/PIK3R1 7 GO:0031023 microtubule organizing center organization 4/504 143/18722 0.539602923228485 0.689297275739103 PKD2/MAP9/ROCK2/PPP1R12A 4 GO:1905952 regulation of lipid localization 5/504 181/18722 0.539758643721751 0.689297275739103 THBS1/AGTR1/LIPG/CAV1/TSPO 5 GO:0000041 transition metal ion transport 3/504 105/18722 0.540077272596312 0.689345515199389 CYBRD1/SLC39A6/B2M 3 GO:0046879 hormone secretion 8/504 295/18722 0.541683098200782 0.689345515199389 AGTR1/CAMK2N1/LTBP4/SOX4/MAP4K4/ITSN1/CLOCK/RAB11FIP2 8 GO:0009880 embryonic pattern specification 2/504 67/18722 0.541927208129017 0.689345515199389 MEIS1/SMAD5 2 GO:0032890 regulation of organic acid transport 2/504 67/18722 0.541927208129017 0.689345515199389 THBS1/ITGB1 2 GO:0042490 mechanoreceptor differentiation 2/504 67/18722 0.541927208129017 0.689345515199389 CTHRC1/JAG1 2 GO:0043967 histone H4 acetylation 2/504 67/18722 0.541927208129017 0.689345515199389 KMT2A/EPC1 2 GO:0048814 regulation of dendrite morphogenesis 2/504 67/18722 0.541927208129017 0.689345515199389 SDC2/RAP2A 2 GO:0072665 protein localization to vacuole 2/504 67/18722 0.541927208129017 0.689345515199389 CD81/ROCK2 2 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 2/504 67/18722 0.541927208129017 0.689345515199389 TWSG1/CD81 2 GO:0051260 protein homooligomerization 5/504 182/18722 0.544665911483829 0.689345515199389 ATL3/B2M/KCTD12/PKD2/GLS 5 GO:0010324 membrane invagination 4/504 144/18722 0.545117482202662 0.689345515199389 THBS1/MFGE8/MYH9/GSN 4 GO:0010821 regulation of mitochondrion organization 4/504 144/18722 0.545117482202662 0.689345515199389 DCN/HGF/TSPO/STAT2 4 GO:0106106 cold-induced thermogenesis 4/504 144/18722 0.545117482202662 0.689345515199389 LAMA4/GATM/ADAMTS5/CAV1 4 GO:0120161 regulation of cold-induced thermogenesis 4/504 144/18722 0.545117482202662 0.689345515199389 LAMA4/GATM/ADAMTS5/CAV1 4 GO:0001824 blastocyst development 3/504 106/18722 0.546504197864937 0.689345515199389 CITED2/CMTM3/NBN 3 GO:0002793 positive regulation of peptide secretion 3/504 106/18722 0.546504197864937 0.689345515199389 CAMK2N1/SOX4/ITSN1 3 GO:0019882 antigen processing and presentation 3/504 106/18722 0.546504197864937 0.689345515199389 THBS1/EXT1/B2M 3 GO:1903707 negative regulation of hemopoiesis 3/504 106/18722 0.546504197864937 0.689345515199389 MDK/FBN1/PIK3R1 3 GO:0001773 myeloid dendritic cell activation 1/504 29/18722 0.547056082855401 0.689345515199389 NOTCH2 1 GO:0001916 positive regulation of T cell mediated cytotoxicity 1/504 29/18722 0.547056082855401 0.689345515199389 B2M 1 GO:0002068 glandular epithelial cell development 1/504 29/18722 0.547056082855401 0.689345515199389 CLOCK 1 GO:0002360 T cell lineage commitment 1/504 29/18722 0.547056082855401 0.689345515199389 STAT3 1 GO:0003309 type B pancreatic cell differentiation 1/504 29/18722 0.547056082855401 0.689345515199389 CLOCK 1 GO:0007143 female meiotic nuclear division 1/504 29/18722 0.547056082855401 0.689345515199389 PRKAR1A 1 GO:0010390 histone monoubiquitination 1/504 29/18722 0.547056082855401 0.689345515199389 PCGF5 1 GO:0010458 exit from mitosis 1/504 29/18722 0.547056082855401 0.689345515199389 EPS8 1 GO:0015868 purine ribonucleotide transport 1/504 29/18722 0.547056082855401 0.689345515199389 SLC25A24 1 GO:0019082 viral protein processing 1/504 29/18722 0.547056082855401 0.689345515199389 MAN2A1 1 GO:0019359 nicotinamide nucleotide biosynthetic process 1/504 29/18722 0.547056082855401 0.689345515199389 NNMT 1 GO:0019363 pyridine nucleotide biosynthetic process 1/504 29/18722 0.547056082855401 0.689345515199389 NNMT 1 GO:0019433 triglyceride catabolic process 1/504 29/18722 0.547056082855401 0.689345515199389 LIPG 1 GO:0021522 spinal cord motor neuron differentiation 1/504 29/18722 0.547056082855401 0.689345515199389 SOX4 1 GO:0021602 cranial nerve morphogenesis 1/504 29/18722 0.547056082855401 0.689345515199389 CITED2 1 GO:0021772 olfactory bulb development 1/504 29/18722 0.547056082855401 0.689345515199389 EXT1 1 GO:0030970 retrograde protein transport, ER to cytosol 1/504 29/18722 0.547056082855401 0.689345515199389 HSP90B1 1 GO:0034311 diol metabolic process 1/504 29/18722 0.547056082855401 0.689345515199389 PLPP1 1 GO:0040018 positive regulation of multicellular organism growth 1/504 29/18722 0.547056082855401 0.689345515199389 IGF2 1 GO:0048753 pigment granule organization 1/504 29/18722 0.547056082855401 0.689345515199389 ZEB2 1 GO:0062098 regulation of programmed necrotic cell death 1/504 29/18722 0.547056082855401 0.689345515199389 CAV1 1 GO:0070198 protein localization to chromosome, telomeric region 1/504 29/18722 0.547056082855401 0.689345515199389 ATRX 1 GO:0070979 protein K11-linked ubiquitination 1/504 29/18722 0.547056082855401 0.689345515199389 UBE2E3 1 GO:0072539 T-helper 17 cell differentiation 1/504 29/18722 0.547056082855401 0.689345515199389 STAT3 1 GO:1900117 regulation of execution phase of apoptosis 1/504 29/18722 0.547056082855401 0.689345515199389 DLC1 1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1/504 29/18722 0.547056082855401 0.689345515199389 HSPB1 1 GO:1903513 endoplasmic reticulum to cytosol transport 1/504 29/18722 0.547056082855401 0.689345515199389 HSP90B1 1 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 2/504 68/18722 0.549960210290206 0.69239245096348 TMSB4X/STAT3 2 GO:0009988 cell-cell recognition 2/504 68/18722 0.549960210290206 0.69239245096348 CD81/MSN 2 GO:0051926 negative regulation of calcium ion transport 2/504 68/18722 0.549960210290206 0.69239245096348 PKD2/CALM2 2 GO:0007269 neurotransmitter secretion 4/504 145/18722 0.550597798044654 0.692582982350546 MEF2C/PREPL/CTBP2/NR4A1 4 GO:0043524 negative regulation of neuron apoptotic process 4/504 145/18722 0.550597798044654 0.692582982350546 AXL/MEF2C/MDK/HIPK2 4 GO:0099643 signal release from synapse 4/504 145/18722 0.550597798044654 0.692582982350546 MEF2C/PREPL/CTBP2/NR4A1 4 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3/504 107/18722 0.552878428071975 0.694838095044573 CD81/IL1R1/B2M 3 GO:0071868 cellular response to monoamine stimulus 3/504 107/18722 0.552878428071975 0.694838095044573 FLNA/ATP2B4/CAV2 3 GO:0071870 cellular response to catecholamine stimulus 3/504 107/18722 0.552878428071975 0.694838095044573 FLNA/ATP2B4/CAV2 3 GO:0048285 organelle fission 13/504 488/18722 0.555190725646357 0.696924356790416 DCN/PDGFRB/PDE3A/FLNA/HSPA2/EPS8/IGF2/CAV2/MAP9/P3H4/PRKAR1A/ATRX/STAT2 13 GO:0051321 meiotic cell cycle 7/504 261/18722 0.557319742522199 0.696924356790416 PDE3A/HSPA2/MYH9/P3H4/PRKAR1A/ATRX/NBN 7 GO:0006368 transcription elongation from RNA polymerase II promoter 2/504 69/18722 0.557893704411456 0.696924356790416 ZMYND11/ZMIZ1 2 GO:0009145 purine nucleoside triphosphate biosynthetic process 2/504 69/18722 0.557893704411456 0.696924356790416 TMSB4X/STAT3 2 GO:0015807 L-amino acid transport 2/504 69/18722 0.557893704411456 0.696924356790416 ITGB1/SLC38A2 2 GO:0070192 chromosome organization involved in meiotic cell cycle 2/504 69/18722 0.557893704411456 0.696924356790416 P3H4/ATRX 2 GO:1901224 positive regulation of NIK/NF-kappaB signaling 2/504 69/18722 0.557893704411456 0.696924356790416 LIMS1/ACTN4 2 GO:0002274 myeloid leukocyte activation 6/504 223/18722 0.557988446509761 0.696924356790416 PLA2G2A/THBS1/NOTCH2/KMT2E/ADAM9/PJA2 6 GO:0006958 complement activation, classical pathway 3/504 108/18722 0.559199249856159 0.696924356790416 C1R/C1S/SERPING1 3 GO:0007173 epidermal growth factor receptor signaling pathway 3/504 108/18722 0.559199249856159 0.696924356790416 ITGA1/HIP1/SOS1 3 GO:0033138 positive regulation of peptidyl-serine phosphorylation 3/504 108/18722 0.559199249856159 0.696924356790416 GAS6/ATP2B4/CAV1 3 GO:0098659 inorganic cation import across plasma membrane 3/504 108/18722 0.559199249856159 0.696924356790416 SLC8A1/ATP2B4/SLC39A6 3 GO:0099587 inorganic ion import across plasma membrane 3/504 108/18722 0.559199249856159 0.696924356790416 SLC8A1/ATP2B4/SLC39A6 3 GO:0043433 negative regulation of DNA-binding transcription factor activity 5/504 185/18722 0.559237192986143 0.696924356790416 HAND2/FLNA/GAS6/TMSB4X/PKD2 5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 1/504 30/18722 0.559268340611827 0.696924356790416 CALM2 1 GO:0015865 purine nucleotide transport 1/504 30/18722 0.559268340611827 0.696924356790416 SLC25A24 1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 1/504 30/18722 0.559268340611827 0.696924356790416 B2M 1 GO:0031365 N-terminal protein amino acid modification 1/504 30/18722 0.559268340611827 0.696924356790416 SOX4 1 GO:0031571 mitotic G1 DNA damage checkpoint signaling 1/504 30/18722 0.559268340611827 0.696924356790416 SOX4 1 GO:0043032 positive regulation of macrophage activation 1/504 30/18722 0.559268340611827 0.696924356790416 THBS1 1 GO:0044030 regulation of DNA methylation 1/504 30/18722 0.559268340611827 0.696924356790416 KMT2A 1 GO:0045940 positive regulation of steroid metabolic process 1/504 30/18722 0.559268340611827 0.696924356790416 AGTR1 1 GO:0048799 animal organ maturation 1/504 30/18722 0.559268340611827 0.696924356790416 EXT1 1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 1/504 30/18722 0.559268340611827 0.696924356790416 THY1 1 GO:0060218 hematopoietic stem cell differentiation 1/504 30/18722 0.559268340611827 0.696924356790416 EXT1 1 GO:0060292 long-term synaptic depression 1/504 30/18722 0.559268340611827 0.696924356790416 PTEN 1 GO:0090314 positive regulation of protein targeting to membrane 1/504 30/18722 0.559268340611827 0.696924356790416 STOM 1 GO:0099068 postsynapse assembly 1/504 30/18722 0.559268340611827 0.696924356790416 PTEN 1 GO:2000648 positive regulation of stem cell proliferation 1/504 30/18722 0.559268340611827 0.696924356790416 FERMT2 1 GO:1902652 secondary alcohol metabolic process 4/504 147/18722 0.561453347327975 0.699443193333071 LIMA1/CYB5R3/ACLY/NFE2L1 4 GO:2001234 negative regulation of apoptotic signaling pathway 6/504 224/18722 0.562375457387476 0.700387738098713 THBS1/HGF/HSPB1/ZMYND11/XBP1/PEA15 6 GO:0042886 amide transport 8/504 301/18722 0.564614451024888 0.702971313878015 CAMK2N1/LTBP4/MGST1/SOX4/MAP4K4/ITSN1/CLOCK/RAB11FIP2 8 GO:0006821 chloride transport 3/504 109/18722 0.565465996156625 0.703826449629262 FXYD1/TSPO/PCYOX1 3 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 2/504 70/18722 0.565727217057145 0.703946534212342 B2M/NBN 2 GO:0070507 regulation of microtubule cytoskeleton organization 4/504 148/18722 0.566827466565428 0.705110266269017 MAP1B/MAP9/ARL3/TAOK1 4 GO:0002828 regulation of type 2 immune response 1/504 31/18722 0.571151967635775 0.706376948685287 CD81 1 GO:0006613 cotranslational protein targeting to membrane 1/504 31/18722 0.571151967635775 0.706376948685287 SEC62 1 GO:0007190 activation of adenylate cyclase activity 1/504 31/18722 0.571151967635775 0.706376948685287 EDNRA 1 GO:0008045 motor neuron axon guidance 1/504 31/18722 0.571151967635775 0.706376948685287 CHN1 1 GO:0021988 olfactory lobe development 1/504 31/18722 0.571151967635775 0.706376948685287 EXT1 1 GO:0030212 hyaluronan metabolic process 1/504 31/18722 0.571151967635775 0.706376948685287 HGF 1 GO:0032148 activation of protein kinase B activity 1/504 31/18722 0.571151967635775 0.706376948685287 GAS6 1 GO:0032509 endosome transport via multivesicular body sorting pathway 1/504 31/18722 0.571151967635775 0.706376948685287 TMEM50B 1 GO:0036474 cell death in response to hydrogen peroxide 1/504 31/18722 0.571151967635775 0.706376948685287 HGF 1 GO:0036475 neuron death in response to oxidative stress 1/504 31/18722 0.571151967635775 0.706376948685287 NCOA7 1 GO:0042133 neurotransmitter metabolic process 1/504 31/18722 0.571151967635775 0.706376948685287 MAOA 1 GO:0044819 mitotic G1/S transition checkpoint signaling 1/504 31/18722 0.571151967635775 0.706376948685287 SOX4 1 GO:0045066 regulatory T cell differentiation 1/504 31/18722 0.571151967635775 0.706376948685287 MDK 1 GO:0045987 positive regulation of smooth muscle contraction 1/504 31/18722 0.571151967635775 0.706376948685287 MYOCD 1 GO:0048710 regulation of astrocyte differentiation 1/504 31/18722 0.571151967635775 0.706376948685287 IL6ST 1 GO:0050482 arachidonic acid secretion 1/504 31/18722 0.571151967635775 0.706376948685287 PLA2G2A 1 GO:0051443 positive regulation of ubiquitin-protein transferase activity 1/504 31/18722 0.571151967635775 0.706376948685287 PTEN 1 GO:0097106 postsynaptic density organization 1/504 31/18722 0.571151967635775 0.706376948685287 PTEN 1 GO:1903963 arachidonate transport 1/504 31/18722 0.571151967635775 0.706376948685287 PLA2G2A 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/504 31/18722 0.571151967635775 0.706376948685287 JUN 1 GO:0007088 regulation of mitotic nuclear division 3/504 110/18722 0.571678045056399 0.706414195062461 PDGFRB/IGF2/CAV2 3 GO:0009063 cellular amino acid catabolic process 3/504 110/18722 0.571678045056399 0.706414195062461 ATP2B4/DDAH2/GLS 3 GO:0048259 regulation of receptor-mediated endocytosis 3/504 110/18722 0.571678045056399 0.706414195062461 HIP1/B2M/MKLN1 3 GO:0071867 response to monoamine 3/504 111/18722 0.577834818632695 0.713609300583094 FLNA/ATP2B4/CAV2 3 GO:0071869 response to catecholamine 3/504 111/18722 0.577834818632695 0.713609300583094 FLNA/ATP2B4/CAV2 3 GO:0002534 cytokine production involved in inflammatory response 2/504 72/18722 0.581092886129302 0.714815907469038 APOD/STAT3 2 GO:0032729 positive regulation of interferon-gamma production 2/504 72/18722 0.581092886129302 0.714815907469038 IL1R1/ISG15 2 GO:1900015 regulation of cytokine production involved in inflammatory response 2/504 72/18722 0.581092886129302 0.714815907469038 APOD/STAT3 2 GO:0009954 proximal/distal pattern formation 1/504 32/18722 0.582715790240857 0.714815907469038 PBX1 1 GO:0014044 Schwann cell development 1/504 32/18722 0.582715790240857 0.714815907469038 LAMB2 1 GO:0019835 cytolysis 1/504 32/18722 0.582715790240857 0.714815907469038 PLA2G2A 1 GO:0033687 osteoblast proliferation 1/504 32/18722 0.582715790240857 0.714815907469038 CTHRC1 1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 1/504 32/18722 0.582715790240857 0.714815907469038 ZMYND11 1 GO:0035883 enteroendocrine cell differentiation 1/504 32/18722 0.582715790240857 0.714815907469038 CLOCK 1 GO:0042219 cellular modified amino acid catabolic process 1/504 32/18722 0.582715790240857 0.714815907469038 PCYOX1 1 GO:0042744 hydrogen peroxide catabolic process 1/504 32/18722 0.582715790240857 0.714815907469038 PXDN 1 GO:0050850 positive regulation of calcium-mediated signaling 1/504 32/18722 0.582715790240857 0.714815907469038 LMCD1 1 GO:0061037 negative regulation of cartilage development 1/504 32/18722 0.582715790240857 0.714815907469038 CTSK 1 GO:0072525 pyridine-containing compound biosynthetic process 1/504 32/18722 0.582715790240857 0.714815907469038 NNMT 1 GO:0090022 regulation of neutrophil chemotaxis 1/504 32/18722 0.582715790240857 0.714815907469038 MDK 1 GO:1901185 negative regulation of ERBB signaling pathway 1/504 32/18722 0.582715790240857 0.714815907469038 ITGA1 1 GO:1901532 regulation of hematopoietic progenitor cell differentiation 1/504 32/18722 0.582715790240857 0.714815907469038 SOS1 1 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/504 32/18722 0.582715790240857 0.714815907469038 XBP1 1 GO:1903955 positive regulation of protein targeting to mitochondrion 1/504 32/18722 0.582715790240857 0.714815907469038 TOMM7 1 GO:1905476 negative regulation of protein localization to membrane 1/504 32/18722 0.582715790240857 0.714815907469038 RHOQ 1 GO:2000191 regulation of fatty acid transport 1/504 32/18722 0.582715790240857 0.714815907469038 THBS1 1 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 1/504 32/18722 0.582715790240857 0.714815907469038 TWSG1 1 GO:0055067 monovalent inorganic cation homeostasis 4/504 151/18722 0.582729028783944 0.714815907469038 AGTR1/SLC8A1/EXT1/EDNRB 4 GO:0009566 fertilization 5/504 190/18722 0.582994017676011 0.714815907469038 MFGE8/ADCY3/NR2F2/MYH9/FNDC3A 5 GO:0099111 microtubule-based transport 5/504 190/18722 0.582994017676011 0.714815907469038 MAP1B/DST/HSPB1/ARL3/ARMCX3 5 GO:0006650 glycerophospholipid metabolic process 8/504 306/18722 0.583335189261932 0.714823993035914 PLA2G2A/PDGFRB/INPP4B/FAM126A/LPGAT1/PDGFA/PIK3R1/PTEN 8 GO:0009914 hormone transport 8/504 306/18722 0.583335189261932 0.714823993035914 AGTR1/CAMK2N1/LTBP4/SOX4/MAP4K4/ITSN1/CLOCK/RAB11FIP2 8 GO:0000956 nuclear-transcribed mRNA catabolic process 3/504 112/18722 0.583935781815071 0.714878911517469 ZFP36L1/ZFP36/TNRC6B 3 GO:0035601 protein deacylation 3/504 112/18722 0.583935781815071 0.714878911517469 NNMT/FLNA/HDAC7 3 GO:0071695 anatomical structure maturation 6/504 229/18722 0.583994012553117 0.714878911517469 PDE3A/AXL/TGFB2/MMP2/EXT1/EDNRB 6 GO:0006644 phospholipid metabolic process 10/504 383/18722 0.584049211352091 0.714878911517469 PLA2G2A/PDGFRB/PLPP1/INPP4B/LIPG/FAM126A/LPGAT1/PDGFA/PIK3R1/PTEN 10 GO:0022412 cellular process involved in reproduction in multicellular organism 10/504 384/18722 0.587364397880277 0.718730833946857 SLIT3/PDE3A/ITGB1/MDK/HSPA2/FNDC3A/SMAD5/PRKAR1A/ZMIZ1/SOS1 10 GO:0016125 sterol metabolic process 4/504 152/18722 0.587954374694954 0.718835205456807 LIMA1/CYB5R3/ACLY/NFE2L1 4 GO:0016573 histone acetylation 4/504 152/18722 0.587954374694954 0.718835205456807 MYOCD/CLOCK/KMT2A/EPC1 4 GO:0051092 positive regulation of NF-kappaB transcription factor activity 4/504 152/18722 0.587954374694954 0.718835205456807 MTDH/CAV1/CLOCK/STAT3 4 GO:0051298 centrosome duplication 2/504 73/18722 0.588624563187253 0.719037380931713 PKD2/ROCK2 2 GO:0072089 stem cell proliferation 2/504 73/18722 0.588624563187253 0.719037380931713 FERMT2/ZFP36L1 2 GO:0099518 vesicle cytoskeletal trafficking 2/504 73/18722 0.588624563187253 0.719037380931713 MYO1B/ACTN4 2 GO:0002708 positive regulation of lymphocyte mediated immunity 3/504 113/18722 0.589980441252423 0.720487689474593 CD81/IL1R1/B2M 3 GO:0009259 ribonucleotide metabolic process 10/504 385/18722 0.590667699054385 0.721030387861175 GUCY1A2/PDE8B/ENPP1/ADCY3/PAPSS2/TMSB4X/RHOQ/ELOVL5/STAT3/ACLY 10 GO:0001975 response to amphetamine 1/504 33/18722 0.593968398144474 0.721030387861175 NR4A1 1 GO:0006336 DNA replication-independent nucleosome assembly 1/504 33/18722 0.593968398144474 0.721030387861175 ATRX 1 GO:0006536 glutamate metabolic process 1/504 33/18722 0.593968398144474 0.721030387861175 GLS 1 GO:0006891 intra-Golgi vesicle-mediated transport 1/504 33/18722 0.593968398144474 0.721030387861175 COPZ2 1 GO:0009648 photoperiodism 1/504 33/18722 0.593968398144474 0.721030387861175 CLOCK 1 GO:0010165 response to X-ray 1/504 33/18722 0.593968398144474 0.721030387861175 CCND2 1 GO:0010259 multicellular organism aging 1/504 33/18722 0.593968398144474 0.721030387861175 CRYAB 1 GO:0010984 regulation of lipoprotein particle clearance 1/504 33/18722 0.593968398144474 0.721030387861175 LIPG 1 GO:0019362 pyridine nucleotide metabolic process 1/504 33/18722 0.593968398144474 0.721030387861175 NNMT 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/504 33/18722 0.593968398144474 0.721030387861175 PTEN 1 GO:0046496 nicotinamide nucleotide metabolic process 1/504 33/18722 0.593968398144474 0.721030387861175 NNMT 1 GO:0048333 mesodermal cell differentiation 1/504 33/18722 0.593968398144474 0.721030387861175 ITGB1 1 GO:0060122 inner ear receptor cell stereocilium organization 1/504 33/18722 0.593968398144474 0.721030387861175 CTHRC1 1 GO:0071353 cellular response to interleukin-4 1/504 33/18722 0.593968398144474 0.721030387861175 XBP1 1 GO:0099084 postsynaptic specialization organization 1/504 33/18722 0.593968398144474 0.721030387861175 PTEN 1 GO:0099174 regulation of presynapse organization 1/504 33/18722 0.593968398144474 0.721030387861175 FARP1 1 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 1/504 33/18722 0.593968398144474 0.721030387861175 MAP4 1 GO:1903146 regulation of autophagy of mitochondrion 1/504 33/18722 0.593968398144474 0.721030387861175 TSPO 1 GO:1903715 regulation of aerobic respiration 1/504 33/18722 0.593968398144474 0.721030387861175 COX7A1 1 GO:1905606 regulation of presynapse assembly 1/504 33/18722 0.593968398144474 0.721030387861175 FARP1 1 GO:0023061 signal release 12/504 463/18722 0.594504761313006 0.721476525160601 AGTR1/CAMK2N1/LTBP4/MEF2C/SOX4/PREPL/MAP4K4/ITSN1/CLOCK/CTBP2/NR4A1/RAB11FIP2 12 GO:0002286 T cell activation involved in immune response 3/504 114/18722 0.595968344189704 0.722332461078363 CD81/MDK/STAT3 3 GO:0019751 polyol metabolic process 3/504 114/18722 0.595968344189704 0.722332461078363 PLPP1/INPP4B/PTEN 3 GO:0009201 ribonucleoside triphosphate biosynthetic process 2/504 74/18722 0.596055290840699 0.722332461078363 TMSB4X/STAT3 2 GO:0051881 regulation of mitochondrial membrane potential 2/504 74/18722 0.596055290840699 0.722332461078363 DCN/TSPO 2 GO:0070972 protein localization to endoplasmic reticulum 2/504 74/18722 0.596055290840699 0.722332461078363 BCAP29/SEC62 2 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 5/504 193/18722 0.596913155045144 0.72316697235835 HGF/GAS6/CD81/IL6ST/IGF2 5 GO:0009100 glycoprotein metabolic process 10/504 387/18722 0.59723797844876 0.723355408705088 DCN/ADAMTS9/RAMP1/BGN/SULF2/EXT1/DSEL/UGDH/MAN2A1/BMPR2 10 GO:0051168 nuclear export 4/504 154/18722 0.598289709366886 0.724423895756504 GAS6/IFI27/ATXN1/AKAP13 4 GO:0042471 ear morphogenesis 3/504 115/18722 0.601899077355226 0.726275711817463 CTHRC1/TSHZ1/PTK7 3 GO:0043279 response to alkaloid 3/504 115/18722 0.601899077355226 0.726275711817463 SLC8A1/MAP1LC3A/PEA15 3 GO:0046916 cellular transition metal ion homeostasis 3/504 115/18722 0.601899077355226 0.726275711817463 MT1E/CYBRD1/SLC39A6 3 GO:0002449 lymphocyte mediated immunity 9/504 350/18722 0.602609306288216 0.726275711817463 C1R/C1S/JAG1/CD81/IL1R1/SERPING1/B2M/NBN/AHR 9 GO:0006094 gluconeogenesis 2/504 75/18722 0.603385035567783 0.726275711817463 NNMT/ATF3 2 GO:0034121 regulation of toll-like receptor signaling pathway 2/504 75/18722 0.603385035567783 0.726275711817463 CAV1/PJA2 2 GO:1903364 positive regulation of cellular protein catabolic process 4/504 155/18722 0.603398911857642 0.726275711817463 CD81/CAV1/MSN/PTEN 4 GO:0000038 very long-chain fatty acid metabolic process 1/504 34/18722 0.604918150797648 0.726275711817463 ELOVL5 1 GO:0002446 neutrophil mediated immunity 1/504 34/18722 0.604918150797648 0.726275711817463 KMT2E 1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 1/504 34/18722 0.604918150797648 0.726275711817463 B2M 1 GO:0006270 DNA replication initiation 1/504 34/18722 0.604918150797648 0.726275711817463 NBN 1 GO:0006356 regulation of transcription by RNA polymerase I 1/504 34/18722 0.604918150797648 0.726275711817463 FLNA 1 GO:0010661 positive regulation of muscle cell apoptotic process 1/504 34/18722 0.604918150797648 0.726275711817463 PTEN 1 GO:0016242 negative regulation of macroautophagy 1/504 34/18722 0.604918150797648 0.726275711817463 QSOX1 1 GO:0019076 viral release from host cell 1/504 34/18722 0.604918150797648 0.726275711817463 CAV2 1 GO:0030851 granulocyte differentiation 1/504 34/18722 0.604918150797648 0.726275711817463 CITED2 1 GO:0032743 positive regulation of interleukin-2 production 1/504 34/18722 0.604918150797648 0.726275711817463 SPTBN1 1 GO:0034724 DNA replication-independent nucleosome organization 1/504 34/18722 0.604918150797648 0.726275711817463 ATRX 1 GO:0035137 hindlimb morphogenesis 1/504 34/18722 0.604918150797648 0.726275711817463 GPC3 1 GO:0035308 negative regulation of protein dephosphorylation 1/504 34/18722 0.604918150797648 0.726275711817463 ROCK2 1 GO:0035890 exit from host 1/504 34/18722 0.604918150797648 0.726275711817463 CAV2 1 GO:0035891 exit from host cell 1/504 34/18722 0.604918150797648 0.726275711817463 CAV2 1 GO:0042573 retinoic acid metabolic process 1/504 34/18722 0.604918150797648 0.726275711817463 RBP1 1 GO:0048741 skeletal muscle fiber development 1/504 34/18722 0.604918150797648 0.726275711817463 CAV2 1 GO:0051085 chaperone cofactor-dependent protein refolding 1/504 34/18722 0.604918150797648 0.726275711817463 HSPA2 1 GO:0051973 positive regulation of telomerase activity 1/504 34/18722 0.604918150797648 0.726275711817463 PARM1 1 GO:0070050 neuron cellular homeostasis 1/504 34/18722 0.604918150797648 0.726275711817463 TAOK1 1 GO:0086004 regulation of cardiac muscle cell contraction 1/504 34/18722 0.604918150797648 0.726275711817463 CAV1 1 GO:1904893 negative regulation of receptor signaling pathway via STAT 1/504 34/18722 0.604918150797648 0.726275711817463 CAV1 1 GO:2000758 positive regulation of peptidyl-lysine acetylation 1/504 34/18722 0.604918150797648 0.726275711817463 SOX4 1 GO:0030073 insulin secretion 5/504 195/18722 0.606047065884859 0.727426717001686 CAMK2N1/SOX4/MAP4K4/CLOCK/RAB11FIP2 5 GO:0006720 isoprenoid metabolic process 3/504 116/18722 0.607772265859275 0.729087841666671 RBP1/RARRES2/DHRS3 3 GO:0098732 macromolecule deacylation 3/504 116/18722 0.607772265859275 0.729087841666671 NNMT/FLNA/HDAC7 3 GO:0090276 regulation of peptide hormone secretion 5/504 196/18722 0.610569412090151 0.731674967078226 CAMK2N1/SOX4/MAP4K4/ITSN1/CLOCK 5 GO:0021536 diencephalon development 2/504 76/18722 0.610613838661585 0.731674967078226 SEMA5A/ETS1 2 GO:0045685 regulation of glial cell differentiation 2/504 76/18722 0.610613838661585 0.731674967078226 MDK/IL6ST 2 GO:0140029 exocytic process 2/504 76/18722 0.610613838661585 0.731674967078226 SYTL2/CTBP2 2 GO:0002366 leukocyte activation involved in immune response 7/504 275/18722 0.612574706175571 0.733503684688044 LGALS1/CD81/MDK/NOTCH2/XBP1/STAT3/NBN 7 GO:0046486 glycerolipid metabolic process 10/504 392/18722 0.613444350408079 0.733503684688044 PLA2G2A/PDGFRB/INPP4B/LIPG/CAV1/FAM126A/LPGAT1/PDGFA/PIK3R1/PTEN 10 GO:1902600 proton transmembrane transport 4/504 157/18722 0.613498584902249 0.733503684688044 COX4I2/COX7A1/TMSB4X/ACTN4 4 GO:1990845 adaptive thermogenesis 4/504 157/18722 0.613498584902249 0.733503684688044 LAMA4/GATM/ADAMTS5/CAV1 4 GO:0006084 acetyl-CoA metabolic process 1/504 35/18722 0.615573183545828 0.733503684688044 ACLY 1 GO:0015695 organic cation transport 1/504 35/18722 0.615573183545828 0.733503684688044 SLC38A2 1 GO:0032205 negative regulation of telomere maintenance 1/504 35/18722 0.615573183545828 0.733503684688044 NBN 1 GO:0032350 regulation of hormone metabolic process 1/504 35/18722 0.615573183545828 0.733503684688044 EGR1 1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1/504 35/18722 0.615573183545828 0.733503684688044 KANK2 1 GO:0033280 response to vitamin D 1/504 35/18722 0.615573183545828 0.733503684688044 KANK2 1 GO:0039694 viral RNA genome replication 1/504 35/18722 0.615573183545828 0.733503684688044 ROCK2 1 GO:0045880 positive regulation of smoothened signaling pathway 1/504 35/18722 0.615573183545828 0.733503684688044 GPC3 1 GO:0045907 positive regulation of vasoconstriction 1/504 35/18722 0.615573183545828 0.733503684688044 CAV1 1 GO:0046471 phosphatidylglycerol metabolic process 1/504 35/18722 0.615573183545828 0.733503684688044 LPGAT1 1 GO:0046627 negative regulation of insulin receptor signaling pathway 1/504 35/18722 0.615573183545828 0.733503684688044 ENPP1 1 GO:0048821 erythrocyte development 1/504 35/18722 0.615573183545828 0.733503684688044 CITED2 1 GO:0060236 regulation of mitotic spindle organization 1/504 35/18722 0.615573183545828 0.733503684688044 MAP9 1 GO:0086005 ventricular cardiac muscle cell action potential 1/504 35/18722 0.615573183545828 0.733503684688044 CAV1 1 GO:0097421 liver regeneration 1/504 35/18722 0.615573183545828 0.733503684688044 SULF2 1 GO:0098810 neurotransmitter reuptake 1/504 35/18722 0.615573183545828 0.733503684688044 ITGB1 1 GO:0018393 internal peptidyl-lysine acetylation 4/504 158/18722 0.618488398289114 0.736771933618451 MYOCD/CLOCK/KMT2A/EPC1 4 GO:0071346 cellular response to interferon-gamma 3/504 118/18722 0.619344694710632 0.737388194552354 VIM/JAK1/ACTG1 3 GO:0048167 regulation of synaptic plasticity 5/504 198/18722 0.619523430480447 0.737388194552354 MAP1B/MEF2C/NPTN/PTEN/EIF4EBP2 5 GO:0050864 regulation of B cell activation 5/504 198/18722 0.619523430480447 0.737388194552354 MEF2C/CD81/ZFP36L1/XBP1/AHR 5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 2/504 78/18722 0.624769135426745 0.741174889173987 DLC1/HIP1 2 GO:0019319 hexose biosynthetic process 2/504 78/18722 0.624769135426745 0.741174889173987 NNMT/ATF3 2 GO:0032024 positive regulation of insulin secretion 2/504 78/18722 0.624769135426745 0.741174889173987 CAMK2N1/SOX4 2 GO:0009225 nucleotide-sugar metabolic process 1/504 36/18722 0.625941413625183 0.741174889173987 UGDH 1 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 1/504 36/18722 0.625941413625183 0.741174889173987 CAMK2N1 1 GO:0042092 type 2 immune response 1/504 36/18722 0.625941413625183 0.741174889173987 CD81 1 GO:0042755 eating behavior 1/504 36/18722 0.625941413625183 0.741174889173987 STAT3 1 GO:0043949 regulation of cAMP-mediated signaling 1/504 36/18722 0.625941413625183 0.741174889173987 PDE3A 1 GO:0044060 regulation of endocrine process 1/504 36/18722 0.625941413625183 0.741174889173987 AGTR1 1 GO:0044743 protein transmembrane import into intracellular organelle 1/504 36/18722 0.625941413625183 0.741174889173987 TOMM7 1 GO:0045652 regulation of megakaryocyte differentiation 1/504 36/18722 0.625941413625183 0.741174889173987 MEF2C 1 GO:0045746 negative regulation of Notch signaling pathway 1/504 36/18722 0.625941413625183 0.741174889173987 DLK1 1 GO:0051955 regulation of amino acid transport 1/504 36/18722 0.625941413625183 0.741174889173987 ITGB1 1 GO:0060251 regulation of glial cell proliferation 1/504 36/18722 0.625941413625183 0.741174889173987 TSPO 1 GO:0070670 response to interleukin-4 1/504 36/18722 0.625941413625183 0.741174889173987 XBP1 1 GO:0090313 regulation of protein targeting to membrane 1/504 36/18722 0.625941413625183 0.741174889173987 STOM 1 GO:0090322 regulation of superoxide metabolic process 1/504 36/18722 0.625941413625183 0.741174889173987 FBLN5 1 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 1/504 36/18722 0.625941413625183 0.741174889173987 TOMM7 1 GO:0006163 purine nucleotide metabolic process 10/504 396/18722 0.626173964408634 0.741174889173987 GUCY1A2/PDE8B/ENPP1/ADCY3/PAPSS2/TMSB4X/RHOQ/ELOVL5/STAT3/ACLY 10 GO:0019693 ribose phosphate metabolic process 10/504 396/18722 0.626173964408634 0.741174889173987 GUCY1A2/PDE8B/ENPP1/ADCY3/PAPSS2/TMSB4X/RHOQ/ELOVL5/STAT3/ACLY 10 GO:0002263 cell activation involved in immune response 7/504 279/18722 0.627669045463835 0.742738806775677 LGALS1/CD81/MDK/NOTCH2/XBP1/STAT3/NBN 7 GO:0006475 internal protein amino acid acetylation 4/504 160/18722 0.628346490483756 0.742933012510427 MYOCD/CLOCK/KMT2A/EPC1 4 GO:0043271 negative regulation of ion transport 4/504 160/18722 0.628346490483756 0.742933012510427 CAV1/PKD2/CALM2/PTEN 4 GO:0002791 regulation of peptide secretion 5/504 200/18722 0.628354764149938 0.742933012510427 CAMK2N1/SOX4/MAP4K4/ITSN1/CLOCK 5 GO:0032886 regulation of microtubule-based process 6/504 240/18722 0.629545249767882 0.744134675590085 MAP1B/MAP9/ARL3/ROCK2/MACF1/TAOK1 6 GO:0006304 DNA modification 3/504 120/18722 0.63068335819231 0.745273780297494 KMT2E/ATRX/KMT2A 3 GO:0051054 positive regulation of DNA metabolic process 5/504 201/18722 0.632723803144576 0.746911558041619 PDGFRB/PARM1/HGF/ATRX/NBN 5 GO:0001990 regulation of systemic arterial blood pressure by hormone 1/504 37/18722 0.636030545998773 0.746911558041619 AGTR1 1 GO:0003016 respiratory system process 1/504 37/18722 0.636030545998773 0.746911558041619 GLS 1 GO:0006862 nucleotide transport 1/504 37/18722 0.636030545998773 0.746911558041619 SLC25A24 1 GO:0007340 acrosome reaction 1/504 37/18722 0.636030545998773 0.746911558041619 ADCY3 1 GO:0014904 myotube cell development 1/504 37/18722 0.636030545998773 0.746911558041619 CAV2 1 GO:0031646 positive regulation of nervous system process 1/504 37/18722 0.636030545998773 0.746911558041619 HGF 1 GO:0033260 nuclear DNA replication 1/504 37/18722 0.636030545998773 0.746911558041619 ATRX 1 GO:0034260 negative regulation of GTPase activity 1/504 37/18722 0.636030545998773 0.746911558041619 SPRY1 1 GO:0042178 xenobiotic catabolic process 1/504 37/18722 0.636030545998773 0.746911558041619 GSTM3 1 GO:0043368 positive T cell selection 1/504 37/18722 0.636030545998773 0.746911558041619 STAT3 1 GO:0043403 skeletal muscle tissue regeneration 1/504 37/18722 0.636030545998773 0.746911558041619 CD81 1 GO:0043687 post-translational protein modification 1/504 37/18722 0.636030545998773 0.746911558041619 CRTAP 1 GO:0046473 phosphatidic acid metabolic process 1/504 37/18722 0.636030545998773 0.746911558041619 PLA2G2A 1 GO:0051567 histone H3-K9 methylation 1/504 37/18722 0.636030545998773 0.746911558041619 ATRX 1 GO:0051954 positive regulation of amine transport 1/504 37/18722 0.636030545998773 0.746911558041619 ITGB1 1 GO:0071542 dopaminergic neuron differentiation 1/504 37/18722 0.636030545998773 0.746911558041619 WNT2 1 GO:0071985 multivesicular body sorting pathway 1/504 37/18722 0.636030545998773 0.746911558041619 TMEM50B 1 GO:1900016 negative regulation of cytokine production involved in inflammatory response 1/504 37/18722 0.636030545998773 0.746911558041619 APOD 1 GO:1900077 negative regulation of cellular response to insulin stimulus 1/504 37/18722 0.636030545998773 0.746911558041619 ENPP1 1 GO:1905332 positive regulation of morphogenesis of an epithelium 1/504 37/18722 0.636030545998773 0.746911558041619 MDK 1 GO:0002224 toll-like receptor signaling pathway 3/504 121/18722 0.63626446788474 0.746911558041619 CAV1/PJA2/RAB11FIP2 3 GO:0038127 ERBB signaling pathway 3/504 121/18722 0.63626446788474 0.746911558041619 ITGA1/HIP1/SOS1 3 GO:0042752 regulation of circadian rhythm 3/504 121/18722 0.63626446788474 0.746911558041619 ZFHX3/CLOCK/ROCK2 3 GO:0090087 regulation of peptide transport 5/504 202/18722 0.637061451141083 0.747641741479222 CAMK2N1/SOX4/MAP4K4/ITSN1/CLOCK 5 GO:0034250 positive regulation of cellular amide metabolic process 4/504 162/18722 0.638040785284429 0.748585468292247 THBS1/VIM/SOX4/ROCK2 4 GO:0000280 nuclear division 11/504 439/18722 0.638412229560759 0.748739896139428 PDGFRB/PDE3A/FLNA/HSPA2/EPS8/IGF2/CAV2/MAP9/P3H4/PRKAR1A/ATRX 11 GO:0032204 regulation of telomere maintenance 2/504 80/18722 0.638522860176006 0.748739896139428 ATRX/NBN 2 GO:0002443 leukocyte mediated immunity 11/504 440/18722 0.641370692542771 0.751872968240127 SPON2/C1R/C1S/JAG1/CD81/IL1R1/SERPING1/B2M/KMT2E/NBN/AHR 11 GO:1903533 regulation of protein targeting 2/504 81/18722 0.645249922636308 0.753195644575463 STOM/TOMM7 2 GO:0001825 blastocyst formation 1/504 38/18722 0.645848079036858 0.753195644575463 CITED2 1 GO:0002478 antigen processing and presentation of exogenous peptide antigen 1/504 38/18722 0.645848079036858 0.753195644575463 B2M 1 GO:0008210 estrogen metabolic process 1/504 38/18722 0.645848079036858 0.753195644575463 PDGFRA 1 GO:0009595 detection of biotic stimulus 1/504 38/18722 0.645848079036858 0.753195644575463 TSPO 1 GO:0032717 negative regulation of interleukin-8 production 1/504 38/18722 0.645848079036858 0.753195644575463 TMSB4X 1 GO:0035136 forelimb morphogenesis 1/504 38/18722 0.645848079036858 0.753195644575463 ATRX 1 GO:0035337 fatty-acyl-CoA metabolic process 1/504 38/18722 0.645848079036858 0.753195644575463 ELOVL5 1 GO:0042491 inner ear auditory receptor cell differentiation 1/504 38/18722 0.645848079036858 0.753195644575463 JAG1 1 GO:0046676 negative regulation of insulin secretion 1/504 38/18722 0.645848079036858 0.753195644575463 MAP4K4 1 GO:0048713 regulation of oligodendrocyte differentiation 1/504 38/18722 0.645848079036858 0.753195644575463 MDK 1 GO:0051930 regulation of sensory perception of pain 1/504 38/18722 0.645848079036858 0.753195644575463 EDNRB 1 GO:0072524 pyridine-containing compound metabolic process 1/504 38/18722 0.645848079036858 0.753195644575463 NNMT 1 GO:0072538 T-helper 17 type immune response 1/504 38/18722 0.645848079036858 0.753195644575463 STAT3 1 GO:0097242 amyloid-beta clearance 1/504 38/18722 0.645848079036858 0.753195644575463 MYOCD 1 GO:0098926 postsynaptic signal transduction 1/504 38/18722 0.645848079036858 0.753195644575463 STAT3 1 GO:0099622 cardiac muscle cell membrane repolarization 1/504 38/18722 0.645848079036858 0.753195644575463 FLNA 1 GO:1903725 regulation of phospholipid metabolic process 1/504 38/18722 0.645848079036858 0.753195644575463 PDGFA 1 GO:2000279 negative regulation of DNA biosynthetic process 1/504 38/18722 0.645848079036858 0.753195644575463 BMPR2 1 GO:0046364 monosaccharide biosynthetic process 2/504 82/18722 0.651877649866177 0.759605453471004 NNMT/ATF3 2 GO:0046889 positive regulation of lipid biosynthetic process 2/504 82/18722 0.651877649866177 0.759605453471004 LPGAT1/ELOVL5 2 GO:2001252 positive regulation of chromosome organization 2/504 82/18722 0.651877649866177 0.759605453471004 ATRX/NBN 2 GO:0050796 regulation of insulin secretion 4/504 165/18722 0.65227118185769 0.759856804819495 CAMK2N1/SOX4/MAP4K4/CLOCK 4 GO:0010508 positive regulation of autophagy 3/504 124/18722 0.652652994762931 0.760094370842738 DCN/FOXO1/MTDH 3 GO:0001914 regulation of T cell mediated cytotoxicity 1/504 39/18722 0.655401310045498 0.760393645893134 B2M 1 GO:0002701 negative regulation of production of molecular mediator of immune response 1/504 39/18722 0.655401310045498 0.760393645893134 TGFB2 1 GO:0016233 telomere capping 1/504 39/18722 0.655401310045498 0.760393645893134 NBN 1 GO:0032506 cytokinetic process 1/504 39/18722 0.655401310045498 0.760393645893134 MYH9 1 GO:0032728 positive regulation of interferon-beta production 1/504 39/18722 0.655401310045498 0.760393645893134 ISG15 1 GO:0034314 Arp2/3 complex-mediated actin nucleation 1/504 39/18722 0.655401310045498 0.760393645893134 NCKAP1 1 GO:0046461 neutral lipid catabolic process 1/504 39/18722 0.655401310045498 0.760393645893134 LIPG 1 GO:0046464 acylglycerol catabolic process 1/504 39/18722 0.655401310045498 0.760393645893134 LIPG 1 GO:0051084 'de novo' posttranslational protein folding 1/504 39/18722 0.655401310045498 0.760393645893134 HSPA2 1 GO:0051931 regulation of sensory perception 1/504 39/18722 0.655401310045498 0.760393645893134 EDNRB 1 GO:0086091 regulation of heart rate by cardiac conduction 1/504 39/18722 0.655401310045498 0.760393645893134 CAV1 1 GO:0090224 regulation of spindle organization 1/504 39/18722 0.655401310045498 0.760393645893134 MAP9 1 GO:1903115 regulation of actin filament-based movement 1/504 39/18722 0.655401310045498 0.760393645893134 CAV1 1 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 1/504 39/18722 0.655401310045498 0.760393645893134 CD81 1 GO:0140014 mitotic nuclear division 7/504 287/18722 0.656847917104967 0.761865132950468 PDGFRB/FLNA/EPS8/IGF2/CAV2/MAP9/ATRX 7 GO:0051053 negative regulation of DNA metabolic process 3/504 125/18722 0.657997215623069 0.762784075517464 BMPR2/NBN/KMT2A 3 GO:0070585 protein localization to mitochondrion 3/504 125/18722 0.657997215623069 0.762784075517464 TSPO/ISG15/TOMM7 3 GO:0046785 microtubule polymerization 2/504 83/18722 0.658406503753092 0.762844628670543 MAP1B/ARL3 2 GO:1901292 nucleoside phosphate catabolic process 2/504 83/18722 0.658406503753092 0.762844628670543 PDE8B/ENPP1 2 GO:0046883 regulation of hormone secretion 6/504 249/18722 0.664575099213649 0.768212134183068 AGTR1/CAMK2N1/SOX4/MAP4K4/ITSN1/CLOCK 6 GO:0031297 replication fork processing 1/504 40/18722 0.664697340647493 0.768212134183068 ATRX 1 GO:0032892 positive regulation of organic acid transport 1/504 40/18722 0.664697340647493 0.768212134183068 ITGB1 1 GO:0042073 intraciliary transport 1/504 40/18722 0.664697340647493 0.768212134183068 ARL3 1 GO:0070266 necroptotic process 1/504 40/18722 0.664697340647493 0.768212134183068 CAV1 1 GO:1901998 toxin transport 1/504 40/18722 0.664697340647493 0.768212134183068 ANTXR1 1 GO:2000142 regulation of DNA-templated transcription, initiation 1/504 40/18722 0.664697340647493 0.768212134183068 JUN 1 GO:0032370 positive regulation of lipid transport 2/504 84/18722 0.664836993262108 0.768212134183068 LIPG/CAV1 2 GO:0097061 dendritic spine organization 2/504 84/18722 0.664836993262108 0.768212134183068 PDLIM5/PTEN 2 GO:1900542 regulation of purine nucleotide metabolic process 2/504 84/18722 0.664836993262108 0.768212134183068 TMSB4X/STAT3 2 GO:0002706 regulation of lymphocyte mediated immunity 4/504 168/18722 0.666124039175451 0.769491219085348 CD81/IL1R1/B2M/AHR 4 GO:0051224 negative regulation of protein transport 3/504 127/18722 0.668507389267666 0.772035695767766 APOD/PKIG/MAP4K4 3 GO:0000075 cell cycle checkpoint signaling 4/504 169/18722 0.670657110792851 0.773646616306473 SOX4/CLOCK/TAOK1/NBN 4 GO:0009142 nucleoside triphosphate biosynthetic process 2/504 85/18722 0.6711696715769 0.773646616306473 TMSB4X/STAT3 2 GO:0030433 ubiquitin-dependent ERAD pathway 2/504 85/18722 0.6711696715769 0.773646616306473 CAV1/HSP90B1 2 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2/504 85/18722 0.6711696715769 0.773646616306473 IL6ST/CAV1 2 GO:0055072 iron ion homeostasis 2/504 85/18722 0.6711696715769 0.773646616306473 CYBRD1/B2M 2 GO:0072384 organelle transport along microtubule 2/504 85/18722 0.6711696715769 0.773646616306473 MAP1B/ARMCX3 2 GO:0097194 execution phase of apoptosis 2/504 85/18722 0.6711696715769 0.773646616306473 DLC1/TAOK1 2 GO:0006639 acylglycerol metabolic process 3/504 128/18722 0.673673325215643 0.775357982620452 LIPG/CAV1/LPGAT1 3 GO:0032735 positive regulation of interleukin-12 production 1/504 41/18722 0.673743082019597 0.775357982620452 MDK 1 GO:0044786 cell cycle DNA replication 1/504 41/18722 0.673743082019597 0.775357982620452 ATRX 1 GO:0050892 intestinal absorption 1/504 41/18722 0.673743082019597 0.775357982620452 LIMA1 1 GO:1901385 regulation of voltage-gated calcium channel activity 1/504 41/18722 0.673743082019597 0.775357982620452 AHNAK 1 GO:1902116 negative regulation of organelle assembly 1/504 41/18722 0.673743082019597 0.775357982620452 MAP4 1 GO:0046474 glycerophospholipid biosynthetic process 5/504 211/18722 0.674656379956161 0.776199976185427 INPP4B/FAM126A/PDGFA/PIK3R1/PTEN 5 GO:0045017 glycerolipid biosynthetic process 6/504 252/18722 0.675778557532693 0.777281770211896 INPP4B/FAM126A/LPGAT1/PDGFA/PIK3R1/PTEN 6 GO:0006140 regulation of nucleotide metabolic process 2/504 86/18722 0.677405133360101 0.778314636958244 TMSB4X/STAT3 2 GO:0015908 fatty acid transport 2/504 86/18722 0.677405133360101 0.778314636958244 PLA2G2A/THBS1 2 GO:0046928 regulation of neurotransmitter secretion 2/504 86/18722 0.677405133360101 0.778314636958244 MEF2C/PREPL 2 GO:2001251 negative regulation of chromosome organization 2/504 86/18722 0.677405133360101 0.778314636958244 ATRX/NBN 2 GO:0030258 lipid modification 5/504 212/18722 0.678670322673221 0.779265539209645 AGTR1/APOD/PLPP1/INPP4B/PTEN 5 GO:0006638 neutral lipid metabolic process 3/504 129/18722 0.678779858866908 0.779265539209645 LIPG/CAV1/LPGAT1 3 GO:0007093 mitotic cell cycle checkpoint signaling 3/504 129/18722 0.678779858866908 0.779265539209645 SOX4/TAOK1/NBN 3 GO:0008654 phospholipid biosynthetic process 6/504 253/18722 0.679459315649942 0.779836061179748 INPP4B/FAM126A/LPGAT1/PDGFA/PIK3R1/PTEN 6 GO:0009154 purine ribonucleotide catabolic process 1/504 42/18722 0.682545259989841 0.780861016315018 PDE8B 1 GO:0014003 oligodendrocyte development 1/504 42/18722 0.682545259989841 0.780861016315018 PTEN 1 GO:0019432 triglyceride biosynthetic process 1/504 42/18722 0.682545259989841 0.780861016315018 LPGAT1 1 GO:0021575 hindbrain morphogenesis 1/504 42/18722 0.682545259989841 0.780861016315018 DLC1 1 GO:0032467 positive regulation of cytokinesis 1/504 42/18722 0.682545259989841 0.780861016315018 SVIL 1 GO:0035019 somatic stem cell population maintenance 1/504 42/18722 0.682545259989841 0.780861016315018 SOX4 1 GO:0045047 protein targeting to ER 1/504 42/18722 0.682545259989841 0.780861016315018 SEC62 1 GO:0055090 acylglycerol homeostasis 1/504 42/18722 0.682545259989841 0.780861016315018 XBP1 1 GO:0060999 positive regulation of dendritic spine development 1/504 42/18722 0.682545259989841 0.780861016315018 ITSN1 1 GO:0070328 triglyceride homeostasis 1/504 42/18722 0.682545259989841 0.780861016315018 XBP1 1 GO:0071312 cellular response to alkaloid 1/504 42/18722 0.682545259989841 0.780861016315018 SLC8A1 1 GO:2000404 regulation of T cell migration 1/504 42/18722 0.682545259989841 0.780861016315018 APOD 1 GO:0019646 aerobic electron transport chain 2/504 87/18722 0.683544012128572 0.781376020285016 COX4I2/COX7A1 2 GO:0019915 lipid storage 2/504 87/18722 0.683544012128572 0.781376020285016 ENPP1/CAV1 2 GO:0150104 transport across blood-brain barrier 2/504 87/18722 0.683544012128572 0.781376020285016 ATP2B4/SLC38A2 2 GO:0072521 purine-containing compound metabolic process 10/504 416/18722 0.686391431010963 0.784421124554652 GUCY1A2/PDE8B/ENPP1/ADCY3/PAPSS2/TMSB4X/RHOQ/ELOVL5/STAT3/ACLY 10 GO:0010469 regulation of signaling receptor activity 4/504 173/18722 0.688364151338743 0.784568231842286 MEF2C/ITGB1/PTEN/DLGAP4 4 GO:0000723 telomere maintenance 3/504 131/18722 0.688814960858417 0.784568231842286 SMC6/ATRX/NBN 3 GO:0006612 protein targeting to membrane 3/504 131/18722 0.688814960858417 0.784568231842286 CHM/STOM/SEC62 3 GO:0050853 B cell receptor signaling pathway 3/504 131/18722 0.688814960858417 0.784568231842286 MEF2C/CD81/CMTM3 3 GO:1904950 negative regulation of establishment of protein localization 3/504 131/18722 0.688814960858417 0.784568231842286 APOD/PKIG/MAP4K4 3 GO:0007260 tyrosine phosphorylation of STAT protein 2/504 88/18722 0.689586977739454 0.784568231842286 IL6ST/CAV1 2 GO:0010232 vascular transport 2/504 88/18722 0.689586977739454 0.784568231842286 ATP2B4/SLC38A2 2 GO:0001504 neurotransmitter uptake 1/504 43/18722 0.691110419998681 0.784568231842286 ITGB1 1 GO:0002861 regulation of inflammatory response to antigenic stimulus 1/504 43/18722 0.691110419998681 0.784568231842286 CD81 1 GO:0006458 'de novo' protein folding 1/504 43/18722 0.691110419998681 0.784568231842286 HSPA2 1 GO:0014014 negative regulation of gliogenesis 1/504 43/18722 0.691110419998681 0.784568231842286 TSPO 1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 1/504 43/18722 0.691110419998681 0.784568231842286 CDH11 1 GO:0021983 pituitary gland development 1/504 43/18722 0.691110419998681 0.784568231842286 ETS1 1 GO:0030517 negative regulation of axon extension 1/504 43/18722 0.691110419998681 0.784568231842286 SEMA5A 1 GO:0034142 toll-like receptor 4 signaling pathway 1/504 43/18722 0.691110419998681 0.784568231842286 RAB11FIP2 1 GO:0034661 ncRNA catabolic process 1/504 43/18722 0.691110419998681 0.784568231842286 KCNQ1OT1 1 GO:0042088 T-helper 1 type immune response 1/504 43/18722 0.691110419998681 0.784568231842286 IL1R1 1 GO:0042181 ketone biosynthetic process 1/504 43/18722 0.691110419998681 0.784568231842286 EGR1 1 GO:0046636 negative regulation of alpha-beta T cell activation 1/504 43/18722 0.691110419998681 0.784568231842286 TWSG1 1 GO:0090278 negative regulation of peptide hormone secretion 1/504 43/18722 0.691110419998681 0.784568231842286 MAP4K4 1 GO:0098815 modulation of excitatory postsynaptic potential 1/504 43/18722 0.691110419998681 0.784568231842286 PTEN 1 GO:0140353 lipid export from cell 1/504 43/18722 0.691110419998681 0.784568231842286 AGTR1 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/504 43/18722 0.691110419998681 0.784568231842286 FLNA 1 GO:1903793 positive regulation of anion transport 1/504 43/18722 0.691110419998681 0.784568231842286 ITGB1 1 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/504 43/18722 0.691110419998681 0.784568231842286 FGFR1 1 GO:0006997 nucleus organization 3/504 133/18722 0.698613409021293 0.791925859599026 ETS1/SYNE1/HIPK2 3 GO:0046887 positive regulation of hormone secretion 3/504 133/18722 0.698613409021293 0.791925859599026 CAMK2N1/SOX4/ITSN1 3 GO:0002792 negative regulation of peptide secretion 1/504 44/18722 0.699444931927621 0.791925859599026 MAP4K4 1 GO:0006775 fat-soluble vitamin metabolic process 1/504 44/18722 0.699444931927621 0.791925859599026 RBP1 1 GO:0021517 ventral spinal cord development 1/504 44/18722 0.699444931927621 0.791925859599026 SOX4 1 GO:0042554 superoxide anion generation 1/504 44/18722 0.699444931927621 0.791925859599026 SH3PXD2A 1 GO:0089718 amino acid import across plasma membrane 1/504 44/18722 0.699444931927621 0.791925859599026 ITGB1 1 GO:0150076 neuroinflammatory response 1/504 44/18722 0.699444931927621 0.791925859599026 ITGB1 1 GO:1903214 regulation of protein targeting to mitochondrion 1/504 44/18722 0.699444931927621 0.791925859599026 TOMM7 1 GO:1903573 negative regulation of response to endoplasmic reticulum stress 1/504 44/18722 0.699444931927621 0.791925859599026 XBP1 1 GO:0050728 negative regulation of inflammatory response 4/504 176/18722 0.701196471878733 0.793495100226442 WFDC1/HGF/MDK/ZFP36 4 GO:0048477 oogenesis 2/504 90/18722 0.701388016277854 0.793495100226442 PDE3A/MDK 2 GO:0099175 regulation of postsynapse organization 2/504 90/18722 0.701388016277854 0.793495100226442 PDLIM5/PTEN 2 GO:0045088 regulation of innate immune response 5/504 218/18722 0.70205611777247 0.794040707051817 A2M/SERPING1/IFI16/ISG15/STAT2 5 GO:0072594 establishment of protein localization to organelle 10/504 422/18722 0.703264916147327 0.79495679407089 APOD/FLNA/TXNIP/PKIG/TSPO/STAT3/PIK3R1/TOMM7/SEC62/KPNA3 10 GO:0002705 positive regulation of leukocyte mediated immunity 3/504 134/18722 0.703424207437874 0.79495679407089 CD81/IL1R1/B2M 3 GO:0008277 regulation of G protein-coupled receptor signaling pathway 3/504 134/18722 0.703424207437874 0.79495679407089 RAMP1/ATP2B4/ROCK2 3 GO:0007018 microtubule-based movement 9/504 382/18722 0.703985677564697 0.795380962515587 MAP1B/ADCY3/ATP2B4/DST/DYNLT3/HSPB1/MAP4/ARL3/ARMCX3 9 GO:0090150 establishment of protein localization to membrane 6/504 260/18722 0.70446269598388 0.795709516240846 SPTBN1/PREPL/MACF1/CHM/STOM/SEC62 6 GO:0006354 DNA-templated transcription, elongation 2/504 91/18722 0.707147589466313 0.796675228662821 ZMYND11/ZMIZ1 2 GO:0003009 skeletal muscle contraction 1/504 45/18722 0.707554994798831 0.796675228662821 NR4A1 1 GO:0006110 regulation of glycolytic process 1/504 45/18722 0.707554994798831 0.796675228662821 STAT3 1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 1/504 45/18722 0.707554994798831 0.796675228662821 HSPB1 1 GO:0010824 regulation of centrosome duplication 1/504 45/18722 0.707554994798831 0.796675228662821 ROCK2 1 GO:0032309 icosanoid secretion 1/504 45/18722 0.707554994798831 0.796675228662821 PLA2G2A 1 GO:0042551 neuron maturation 1/504 45/18722 0.707554994798831 0.796675228662821 EDNRB 1 GO:0045933 positive regulation of muscle contraction 1/504 45/18722 0.707554994798831 0.796675228662821 MYOCD 1 GO:0048546 digestive tract morphogenesis 1/504 45/18722 0.707554994798831 0.796675228662821 PDGFRA 1 GO:0048599 oocyte development 1/504 45/18722 0.707554994798831 0.796675228662821 PDE3A 1 GO:0060119 inner ear receptor cell development 1/504 45/18722 0.707554994798831 0.796675228662821 CTHRC1 1 GO:2000273 positive regulation of signaling receptor activity 1/504 45/18722 0.707554994798831 0.796675228662821 ITGB1 1 GO:0042157 lipoprotein metabolic process 3/504 135/18722 0.708176267282908 0.797164697075834 APOD/LIPG/APOL6 3 GO:0001708 cell fate specification 2/504 92/18722 0.712814245703739 0.801392406116843 TBX2/ITGB1 2 GO:0031058 positive regulation of histone modification 2/504 92/18722 0.712814245703739 0.801392406116843 KMT2E/KMT2A 2 GO:0035249 synaptic transmission, glutamatergic 2/504 92/18722 0.712814245703739 0.801392406116843 MEF2C/EXT1 2 GO:1903351 cellular response to dopamine 2/504 92/18722 0.712814245703739 0.801392406116843 FLNA/CAV2 2 GO:0045727 positive regulation of translation 3/504 136/18722 0.712869771975222 0.801392406116843 THBS1/VIM/SOX4 3 GO:0006195 purine nucleotide catabolic process 1/504 46/18722 0.715446641349209 0.80302167020887 PDE8B 1 GO:0031648 protein destabilization 1/504 46/18722 0.715446641349209 0.80302167020887 GSN 1 GO:0035094 response to nicotine 1/504 46/18722 0.715446641349209 0.80302167020887 B2M 1 GO:0048701 embryonic cranial skeleton morphogenesis 1/504 46/18722 0.715446641349209 0.80302167020887 PDGFRA 1 GO:0072599 establishment of protein localization to endoplasmic reticulum 1/504 46/18722 0.715446641349209 0.80302167020887 SEC62 1 GO:1900271 regulation of long-term synaptic potentiation 1/504 46/18722 0.715446641349209 0.80302167020887 NPTN 1 GO:0015698 inorganic anion transport 4/504 180/18722 0.717708481612099 0.805348829287946 FXYD1/ENPP1/TSPO/PCYOX1 4 GO:0106027 neuron projection organization 2/504 93/18722 0.718388802440794 0.805477657525456 PDLIM5/PTEN 2 GO:1901796 regulation of signal transduction by p53 class mediator 2/504 93/18722 0.718388802440794 0.805477657525456 DYRK2/HIPK2 2 GO:1903350 response to dopamine 2/504 93/18722 0.718388802440794 0.805477657525456 FLNA/CAV2 2 GO:0006479 protein methylation 4/504 181/18722 0.721729946875157 0.80803250460944 NNMT/KMT2E/ATRX/KMT2A 4 GO:0008213 protein alkylation 4/504 181/18722 0.721729946875157 0.80803250460944 NNMT/KMT2E/ATRX/KMT2A 4 GO:0000724 double-strand break repair via homologous recombination 3/504 138/18722 0.722081942224513 0.80803250460944 REV3L/SMC6/NBN 3 GO:0009261 ribonucleotide catabolic process 1/504 47/18722 0.723125742482213 0.80803250460944 PDE8B 1 GO:0010799 regulation of peptidyl-threonine phosphorylation 1/504 47/18722 0.723125742482213 0.80803250460944 CALM2 1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 1/504 47/18722 0.723125742482213 0.80803250460944 GAS6 1 GO:0016574 histone ubiquitination 1/504 47/18722 0.723125742482213 0.80803250460944 PCGF5 1 GO:0019884 antigen processing and presentation of exogenous antigen 1/504 47/18722 0.723125742482213 0.80803250460944 B2M 1 GO:0032369 negative regulation of lipid transport 1/504 47/18722 0.723125742482213 0.80803250460944 THBS1 1 GO:0035315 hair cell differentiation 1/504 47/18722 0.723125742482213 0.80803250460944 JAG1 1 GO:0045581 negative regulation of T cell differentiation 1/504 47/18722 0.723125742482213 0.80803250460944 MDK 1 GO:0051972 regulation of telomerase activity 1/504 47/18722 0.723125742482213 0.80803250460944 PARM1 1 GO:0097300 programmed necrotic cell death 1/504 47/18722 0.723125742482213 0.80803250460944 CAV1 1 GO:0002440 production of molecular mediator of immune response 7/504 308/18722 0.726591704777377 0.811693164578754 SPON2/TGFB2/CD81/IL1R1/B2M/XBP1/NBN 7 GO:0002532 production of molecular mediator involved in inflammatory response 2/504 95/18722 0.729265002200161 0.813828285602208 APOD/STAT3 2 GO:0042773 ATP synthesis coupled electron transport 2/504 95/18722 0.729265002200161 0.813828285602208 COX4I2/COX7A1 2 GO:0042775 mitochondrial ATP synthesis coupled electron transport 2/504 95/18722 0.729265002200161 0.813828285602208 COX4I2/COX7A1 2 GO:0006111 regulation of gluconeogenesis 1/504 48/18722 0.730598011600766 0.813828285602208 NNMT 1 GO:0015804 neutral amino acid transport 1/504 48/18722 0.730598011600766 0.813828285602208 SLC38A2 1 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 1/504 48/18722 0.730598011600766 0.813828285602208 ATRX 1 GO:0090199 regulation of release of cytochrome c from mitochondria 1/504 48/18722 0.730598011600766 0.813828285602208 HGF 1 GO:0090311 regulation of protein deacetylation 1/504 48/18722 0.730598011600766 0.813828285602208 NNMT 1 GO:0120009 intermembrane lipid transfer 1/504 48/18722 0.730598011600766 0.813828285602208 TSPO 1 GO:1902003 regulation of amyloid-beta formation 1/504 48/18722 0.730598011600766 0.813828285602208 ROCK2 1 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 1/504 48/18722 0.730598011600766 0.813828285602208 HIPK2 1 GO:0000725 recombinational repair 3/504 140/18722 0.731062545656181 0.814133504714324 REV3L/SMC6/NBN 3 GO:0050708 regulation of protein secretion 6/504 268/18722 0.731385689674825 0.814281149551988 CAMK2N1/TGFB2/SOX4/MAP4K4/CLOCK/ADAM9 6 GO:0051047 positive regulation of secretion 7/504 310/18722 0.732696847198613 0.815528426173397 CAMK2N1/TGFB2/EDNRB/SOX4/ITSN1/ADAM9/XBP1 7 GO:0006637 acyl-CoA metabolic process 2/504 96/18722 0.734568389656313 0.816394167453767 ELOVL5/ACLY 2 GO:0035383 thioester metabolic process 2/504 96/18722 0.734568389656313 0.816394167453767 ELOVL5/ACLY 2 GO:0042472 inner ear morphogenesis 2/504 96/18722 0.734568389656313 0.816394167453767 CTHRC1/PTK7 2 GO:0043648 dicarboxylic acid metabolic process 2/504 96/18722 0.734568389656313 0.816394167453767 GLS/ACLY 2 GO:0140013 meiotic nuclear division 4/504 185/18722 0.737391668089289 0.816394167453767 PDE3A/HSPA2/P3H4/PRKAR1A 4 GO:0006066 alcohol metabolic process 8/504 353/18722 0.737633645388875 0.816394167453767 PLPP1/INPP4B/LIMA1/CYB5R3/PTEN/DHRS3/ACLY/NFE2L1 8 GO:0001913 T cell mediated cytotoxicity 1/504 49/18722 0.73786900882435 0.816394167453767 B2M 1 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 1/504 49/18722 0.73786900882435 0.816394167453767 NBN 1 GO:0002208 somatic diversification of immunoglobulins involved in immune response 1/504 49/18722 0.73786900882435 0.816394167453767 NBN 1 GO:0009066 aspartate family amino acid metabolic process 1/504 49/18722 0.73786900882435 0.816394167453767 PLOD2 1 GO:0009395 phospholipid catabolic process 1/504 49/18722 0.73786900882435 0.816394167453767 LIPG 1 GO:0009994 oocyte differentiation 1/504 49/18722 0.73786900882435 0.816394167453767 PDE3A 1 GO:0014075 response to amine 1/504 49/18722 0.73786900882435 0.816394167453767 NR4A1 1 GO:0021695 cerebellar cortex development 1/504 49/18722 0.73786900882435 0.816394167453767 MDK 1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1/504 49/18722 0.73786900882435 0.816394167453767 WWTR1 1 GO:0032692 negative regulation of interleukin-1 production 1/504 49/18722 0.73786900882435 0.816394167453767 GAS6 1 GO:0043330 response to exogenous dsRNA 1/504 49/18722 0.73786900882435 0.816394167453767 CAV1 1 GO:0043457 regulation of cellular respiration 1/504 49/18722 0.73786900882435 0.816394167453767 COX7A1 1 GO:0045190 isotype switching 1/504 49/18722 0.73786900882435 0.816394167453767 NBN 1 GO:0046605 regulation of centrosome cycle 1/504 49/18722 0.73786900882435 0.816394167453767 ROCK2 1 GO:0048168 regulation of neuronal synaptic plasticity 1/504 49/18722 0.73786900882435 0.816394167453767 NPTN 1 GO:0051932 synaptic transmission, GABAergic 1/504 49/18722 0.73786900882435 0.816394167453767 PTEN 1 GO:0060986 endocrine hormone secretion 1/504 49/18722 0.73786900882435 0.816394167453767 AGTR1 1 GO:0035335 peptidyl-tyrosine dephosphorylation 2/504 97/18722 0.73978316303394 0.818088368437895 PTEN/PTPRA 2 GO:0120162 positive regulation of cold-induced thermogenesis 2/504 97/18722 0.73978316303394 0.818088368437895 GATM/CAV1 2 GO:0003333 amino acid transmembrane transport 2/504 98/18722 0.744910238972701 0.820610036603306 ITGB1/SLC38A2 2 GO:0032642 regulation of chemokine production 2/504 98/18722 0.744910238972701 0.820610036603306 APOD/EGR1 2 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 2/504 98/18722 0.744910238972701 0.820610036603306 HSPB1/XBP1 2 GO:0002448 mast cell mediated immunity 1/504 50/18722 0.74494414509343 0.820610036603306 SPON2 1 GO:0002639 positive regulation of immunoglobulin production 1/504 50/18722 0.74494414509343 0.820610036603306 XBP1 1 GO:0007140 male meiotic nuclear division 1/504 50/18722 0.74494414509343 0.820610036603306 HSPA2 1 GO:0008089 anterograde axonal transport 1/504 50/18722 0.74494414509343 0.820610036603306 HSPB1 1 GO:0038093 Fc receptor signaling pathway 1/504 50/18722 0.74494414509343 0.820610036603306 SOS1 1 GO:0042572 retinol metabolic process 1/504 50/18722 0.74494414509343 0.820610036603306 DHRS3 1 GO:0045058 T cell selection 1/504 50/18722 0.74494414509343 0.820610036603306 STAT3 1 GO:0045814 negative regulation of gene expression, epigenetic 1/504 50/18722 0.74494414509343 0.820610036603306 EPC1 1 GO:0046460 neutral lipid biosynthetic process 1/504 50/18722 0.74494414509343 0.820610036603306 LPGAT1 1 GO:0046463 acylglycerol biosynthetic process 1/504 50/18722 0.74494414509343 0.820610036603306 LPGAT1 1 GO:1901570 fatty acid derivative biosynthetic process 1/504 50/18722 0.74494414509343 0.820610036603306 ELOVL5 1 GO:1903747 regulation of establishment of protein localization to mitochondrion 1/504 50/18722 0.74494414509343 0.820610036603306 TOMM7 1 GO:0006869 lipid transport 9/504 398/18722 0.747982679691976 0.823744842866962 PLA2G2A/THBS1/AGTR1/APOD/LIPG/CAV1/LIMA1/TSPO/APOL6 9 GO:0002444 myeloid leukocyte mediated immunity 2/504 99/18722 0.749950549045891 0.824849085218299 SPON2/KMT2E 2 GO:0021549 cerebellum development 2/504 99/18722 0.749950549045891 0.824849085218299 CKB/MDK 2 GO:0031341 regulation of cell killing 2/504 99/18722 0.749950549045891 0.824849085218299 CFH/B2M 2 GO:0032602 chemokine production 2/504 99/18722 0.749950549045891 0.824849085218299 APOD/EGR1 2 GO:0060291 long-term synaptic potentiation 2/504 99/18722 0.749950549045891 0.824849085218299 NPTN/PTEN 2 GO:0006636 unsaturated fatty acid biosynthetic process 1/504 51/18722 0.751828686164173 0.82554561441981 ELOVL5 1 GO:0009948 anterior/posterior axis specification 1/504 51/18722 0.751828686164173 0.82554561441981 GPC3 1 GO:0010874 regulation of cholesterol efflux 1/504 51/18722 0.751828686164173 0.82554561441981 CAV1 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/504 51/18722 0.751828686164173 0.82554561441981 ZMYND11 1 GO:0046850 regulation of bone remodeling 1/504 51/18722 0.751828686164173 0.82554561441981 MDK 1 GO:0050982 detection of mechanical stimulus 1/504 51/18722 0.751828686164173 0.82554561441981 PKD2 1 GO:0006402 mRNA catabolic process 5/504 232/18722 0.751936234805032 0.82554561441981 VIM/ZFP36L1/ZFP36/ROCK2/TNRC6B 5 GO:0009306 protein secretion 8/504 359/18722 0.754171950881557 0.827787502213433 LTBP2/CAMK2N1/TGFB2/SOX4/MAP4K4/CLOCK/ADAM9/RAB11FIP2 8 GO:0006626 protein targeting to mitochondrion 2/504 100/18722 0.754905038296505 0.827954114127557 TSPO/TOMM7 2 GO:0006910 phagocytosis, recognition 2/504 100/18722 0.754905038296505 0.827954114127557 SPON2/MFGE8 2 GO:0060079 excitatory postsynaptic potential 2/504 100/18722 0.754905038296505 0.827954114127557 MEF2C/PTEN 2 GO:0035592 establishment of protein localization to extracellular region 8/504 360/18722 0.756855802958019 0.829880637936776 LTBP2/CAMK2N1/TGFB2/SOX4/MAP4K4/CLOCK/ADAM9/RAB11FIP2 8 GO:0002218 activation of innate immune response 1/504 52/18722 0.758527756496413 0.83043533269515 IFI16 1 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 1/504 52/18722 0.758527756496413 0.83043533269515 COPZ2 1 GO:0007129 homologous chromosome pairing at meiosis 1/504 52/18722 0.758527756496413 0.83043533269515 P3H4 1 GO:0043090 amino acid import 1/504 52/18722 0.758527756496413 0.83043533269515 ITGB1 1 GO:0072523 purine-containing compound catabolic process 1/504 52/18722 0.758527756496413 0.83043533269515 PDE8B 1 GO:1903426 regulation of reactive oxygen species biosynthetic process 1/504 52/18722 0.758527756496413 0.83043533269515 STAT3 1 GO:0046034 ATP metabolic process 6/504 277/18722 0.759554506206986 0.831346415220914 COX4I2/ENPP1/COX7A1/TMSB4X/TSPO/STAT3 6 GO:0050830 defense response to Gram-positive bacterium 2/504 101/18722 0.759774663841023 0.831374427296464 PLA2G2A/RARRES2 2 GO:0002699 positive regulation of immune effector process 5/504 235/18722 0.761774287696763 0.833349086361563 SPON2/CD81/IL1R1/B2M/XBP1 5 GO:0006401 RNA catabolic process 6/504 278/18722 0.762546306798271 0.833939546887777 VIM/KCNQ1OT1/ZFP36L1/ZFP36/ROCK2/TNRC6B 6 GO:0032677 regulation of interleukin-8 production 2/504 102/18722 0.76456039353833 0.833939546887777 TMSB4X/STAT3 2 GO:0045833 negative regulation of lipid metabolic process 2/504 102/18722 0.76456039353833 0.833939546887777 APOD/PDGFA 2 GO:0062014 negative regulation of small molecule metabolic process 2/504 102/18722 0.76456039353833 0.833939546887777 ATP2B4/STAT3 2 GO:0002707 negative regulation of lymphocyte mediated immunity 1/504 53/18722 0.765046343037699 0.833939546887777 AHR 1 GO:0032784 regulation of DNA-templated transcription, elongation 1/504 53/18722 0.765046343037699 0.833939546887777 ZMYND11 1 GO:0033059 cellular pigmentation 1/504 53/18722 0.765046343037699 0.833939546887777 ZEB2 1 GO:0034381 plasma lipoprotein particle clearance 1/504 53/18722 0.765046343037699 0.833939546887777 LIPG 1 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 1/504 53/18722 0.765046343037699 0.833939546887777 ATP2B4 1 GO:0045806 negative regulation of endocytosis 1/504 53/18722 0.765046343037699 0.833939546887777 CAV1 1 GO:0051438 regulation of ubiquitin-protein transferase activity 1/504 53/18722 0.765046343037699 0.833939546887777 PTEN 1 GO:0071715 icosanoid transport 1/504 53/18722 0.765046343037699 0.833939546887777 PLA2G2A 1 GO:0097479 synaptic vesicle localization 1/504 53/18722 0.765046343037699 0.833939546887777 PTEN 1 GO:1990090 cellular response to nerve growth factor stimulus 1/504 53/18722 0.765046343037699 0.833939546887777 PTEN 1 GO:1901617 organic hydroxy compound biosynthetic process 5/504 237/18722 0.768168208640928 0.837128986361307 HAND2/TGFB2/ZEB2/CYB5R3/ACLY 5 GO:1905039 carboxylic acid transmembrane transport 3/504 149/18722 0.768671099023752 0.837254629081522 THBS1/ITGB1/SLC38A2 3 GO:0009117 nucleotide metabolic process 11/504 489/18722 0.769150342770158 0.837254629081522 GUCY1A2/NNMT/PDE8B/ENPP1/ADCY3/PAPSS2/TMSB4X/RHOQ/ELOVL5/STAT3/ACLY 11 GO:0030148 sphingolipid biosynthetic process 2/504 103/18722 0.769263204721286 0.837254629081522 PLPP1/ELOVL5 2 GO:0032637 interleukin-8 production 2/504 103/18722 0.769263204721286 0.837254629081522 TMSB4X/STAT3 2 GO:0050773 regulation of dendrite development 2/504 103/18722 0.769263204721286 0.837254629081522 SDC2/RAP2A 2 GO:0010876 lipid localization 10/504 448/18722 0.769604923701482 0.837413251585544 PLA2G2A/THBS1/AGTR1/APOD/ENPP1/LIPG/CAV1/LIMA1/TSPO/APOL6 10 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1/504 54/18722 0.771389298906197 0.838500756608034 AHR 1 GO:0070228 regulation of lymphocyte apoptotic process 1/504 54/18722 0.771389298906197 0.838500756608034 PTEN 1 GO:0072348 sulfur compound transport 1/504 54/18722 0.771389298906197 0.838500756608034 MGST1 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/504 54/18722 0.771389298906197 0.838500756608034 PREPL 1 GO:1903825 organic acid transmembrane transport 3/504 150/18722 0.77257324814892 0.839574132589099 THBS1/ITGB1/SLC38A2 3 GO:1901605 alpha-amino acid metabolic process 4/504 195/18722 0.773618082175729 0.840357480714141 ATP2B4/DDAH2/GLS/PLOD2 4 GO:0032006 regulation of TOR signaling 2/504 104/18722 0.773884082988567 0.840357480714141 GAS6/AKT3 2 GO:0046634 regulation of alpha-beta T cell activation 2/504 104/18722 0.773884082988567 0.840357480714141 TWSG1/CD81 2 GO:0006261 DNA-dependent DNA replication 3/504 151/18722 0.776421441784697 0.842446436334656 REV3L/ATRX/NBN 3 GO:0006360 transcription by RNA polymerase I 1/504 55/18722 0.777561346975154 0.842446436334656 FLNA 1 GO:0008333 endosome to lysosome transport 1/504 55/18722 0.777561346975154 0.842446436334656 RHOB 1 GO:0043331 response to dsRNA 1/504 55/18722 0.777561346975154 0.842446436334656 CAV1 1 GO:0045620 negative regulation of lymphocyte differentiation 1/504 55/18722 0.777561346975154 0.842446436334656 MDK 1 GO:0051898 negative regulation of protein kinase B signaling 1/504 55/18722 0.777561346975154 0.842446436334656 PTEN 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/504 55/18722 0.777561346975154 0.842446436334656 GAS6 1 GO:1902991 regulation of amyloid precursor protein catabolic process 1/504 55/18722 0.777561346975154 0.842446436334656 ROCK2 1 GO:0044782 cilium organization 8/504 368/18722 0.777582201007228 0.842446436334656 EHD2/FLNA/GSN/PKD2/MAP4/PARVA/WWTR1/ARL3 8 GO:0016079 synaptic vesicle exocytosis 2/504 105/18722 0.778424021054436 0.842931029388141 PREPL/CTBP2 2 GO:0062207 regulation of pattern recognition receptor signaling pathway 2/504 105/18722 0.778424021054436 0.842931029388141 CAV1/PJA2 2 GO:0015850 organic hydroxy compound transport 6/504 284/18722 0.779922420205272 0.844339625421112 AGTR1/LIPG/ACTB/CAV1/LIMA1/TSPO 6 GO:0050871 positive regulation of B cell activation 3/504 152/18722 0.78021608071939 0.844443594963008 MEF2C/CD81/XBP1 3 GO:0002831 regulation of response to biotic stimulus 7/504 327/18722 0.780770144965587 0.844642136882507 A2M/SERPING1/IFI16/HTRA1/ISG15/AHR/STAT2 7 GO:0006766 vitamin metabolic process 2/504 106/18722 0.782884017654234 0.844642136882507 RBP1/NNMT 2 GO:0042116 macrophage activation 2/504 106/18722 0.782884017654234 0.844642136882507 THBS1/PJA2 2 GO:0099565 chemical synaptic transmission, postsynaptic 2/504 106/18722 0.782884017654234 0.844642136882507 MEF2C/PTEN 2 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 1/504 56/18722 0.783567083361532 0.844642136882507 B2M 1 GO:0002090 regulation of receptor internalization 1/504 56/18722 0.783567083361532 0.844642136882507 MKLN1 1 GO:0015800 acidic amino acid transport 1/504 56/18722 0.783567083361532 0.844642136882507 ITGB1 1 GO:0031122 cytoplasmic microtubule organization 1/504 56/18722 0.783567083361532 0.844642136882507 DST 1 GO:0032608 interferon-beta production 1/504 56/18722 0.783567083361532 0.844642136882507 ISG15 1 GO:0032648 regulation of interferon-beta production 1/504 56/18722 0.783567083361532 0.844642136882507 ISG15 1 GO:0043470 regulation of carbohydrate catabolic process 1/504 56/18722 0.783567083361532 0.844642136882507 STAT3 1 GO:0048255 mRNA stabilization 1/504 56/18722 0.783567083361532 0.844642136882507 ZFP36 1 GO:0051784 negative regulation of nuclear division 1/504 56/18722 0.783567083361532 0.844642136882507 PRKAR1A 1 GO:0070534 protein K63-linked ubiquitination 1/504 56/18722 0.783567083361532 0.844642136882507 UBE2E3 1 GO:1904645 response to amyloid-beta 1/504 56/18722 0.783567083361532 0.844642136882507 MMP2 1 GO:1990089 response to nerve growth factor 1/504 56/18722 0.783567083361532 0.844642136882507 PTEN 1 GO:0007338 single fertilization 3/504 153/18722 0.783957574274754 0.844642136882507 MFGE8/ADCY3/MYH9 3 GO:0120254 olefinic compound metabolic process 3/504 153/18722 0.783957574274754 0.844642136882507 EGR1/ELOVL5/DHRS3 3 GO:0006753 nucleoside phosphate metabolic process 11/504 497/18722 0.786624401731402 0.847301756641865 GUCY1A2/NNMT/PDE8B/ENPP1/ADCY3/PAPSS2/TMSB4X/RHOQ/ELOVL5/STAT3/ACLY 11 GO:0008637 apoptotic mitochondrial changes 2/504 107/18722 0.78726507650342 0.8473510508562 HGF/JUN 2 GO:0036503 ERAD pathway 2/504 107/18722 0.78726507650342 0.8473510508562 CAV1/HSP90B1 2 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 2/504 107/18722 0.78726507650342 0.8473510508562 CAV1/PTEN 2 GO:0016447 somatic recombination of immunoglobulin gene segments 1/504 57/18722 0.789410980821394 0.848591980138319 NBN 1 GO:0034205 amyloid-beta formation 1/504 57/18722 0.789410980821394 0.848591980138319 ROCK2 1 GO:0050891 multicellular organismal water homeostasis 1/504 57/18722 0.789410980821394 0.848591980138319 EXT1 1 GO:0097120 receptor localization to synapse 1/504 57/18722 0.789410980821394 0.848591980138319 NPTN 1 GO:1902017 regulation of cilium assembly 1/504 57/18722 0.789410980821394 0.848591980138319 MAP4 1 GO:0022037 metencephalon development 2/504 108/18722 0.791568205308085 0.850696916821289 CKB/MDK 2 GO:0046631 alpha-beta T cell activation 3/504 156/18722 0.79486739341489 0.853416517520447 TWSG1/CD81/STAT3 3 GO:0010559 regulation of glycoprotein biosynthetic process 1/504 58/18722 0.795097392054505 0.853416517520447 RAMP1 1 GO:0032481 positive regulation of type I interferon production 1/504 58/18722 0.795097392054505 0.853416517520447 ISG15 1 GO:0043506 regulation of JUN kinase activity 1/504 58/18722 0.795097392054505 0.853416517520447 AIDA 1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 1/504 58/18722 0.795097392054505 0.853416517520447 CAV1 1 GO:0007030 Golgi organization 3/504 157/18722 0.798400552022279 0.856746750073129 SYNE1/ATL3/VMP1 3 GO:0016236 macroautophagy 6/504 291/18722 0.798964698712063 0.857136871101342 DCN/SYNPO2/QSOX1/VMP1/MAP1LC3A/TOMM7 6 GO:0030317 flagellated sperm motility 2/504 110/18722 0.799944717968797 0.857417130984878 ADCY3/ATP2B4 2 GO:0097722 sperm motility 2/504 110/18722 0.799944717968797 0.857417130984878 ADCY3/ATP2B4 2 GO:1905954 positive regulation of lipid localization 2/504 110/18722 0.799944717968797 0.857417130984878 LIPG/CAV1 2 GO:0002820 negative regulation of adaptive immune response 1/504 59/18722 0.800630552920586 0.857417130984878 AHR 1 GO:0006767 water-soluble vitamin metabolic process 1/504 59/18722 0.800630552920586 0.857417130984878 NNMT 1 GO:0051055 negative regulation of lipid biosynthetic process 1/504 59/18722 0.800630552920586 0.857417130984878 PDGFA 1 GO:0051353 positive regulation of oxidoreductase activity 1/504 59/18722 0.800630552920586 0.857417130984878 AGTR1 1 GO:0016570 histone modification 10/504 463/18722 0.802788198163663 0.859512395578385 NNMT/MYOCD/PCGF5/IGF2/HDAC7/KMT2E/CLOCK/ATRX/KMT2A/EPC1 10 GO:0006805 xenobiotic metabolic process 2/504 111/18722 0.804020128965789 0.860615734236177 GSTM3/AHR 2 GO:0032200 telomere organization 3/504 159/18722 0.80531435601103 0.861671334535597 SMC6/ATRX/NBN 3 GO:0060271 cilium assembly 7/504 337/18722 0.805893228457743 0.861671334535597 EHD2/FLNA/GSN/MAP4/PARVA/WWTR1/ARL3 7 GO:0006289 nucleotide-excision repair 1/504 60/18722 0.806014585569572 0.861671334535597 POLK 1 GO:0019731 antibacterial humoral response 1/504 60/18722 0.806014585569572 0.861671334535597 SPON2 1 GO:0031663 lipopolysaccharide-mediated signaling pathway 1/504 60/18722 0.806014585569572 0.861671334535597 MTDH 1 GO:0019748 secondary metabolic process 1/504 61/18722 0.811253501488173 0.866404951726809 ZEB2 1 GO:0043966 histone H3 acetylation 1/504 61/18722 0.811253501488173 0.866404951726809 KMT2A 1 GO:0050994 regulation of lipid catabolic process 1/504 61/18722 0.811253501488173 0.866404951726809 RARRES2 1 GO:1905515 non-motile cilium assembly 1/504 61/18722 0.811253501488173 0.866404951726809 MAP4 1 GO:0022904 respiratory electron transport chain 2/504 114/18722 0.815807154436769 0.870543722655055 COX4I2/COX7A1 2 GO:0007062 sister chromatid cohesion 1/504 62/18722 0.816351204464967 0.870543722655055 ATRX 1 GO:0031124 mRNA 3'-end processing 1/504 62/18722 0.816351204464967 0.870543722655055 ZFP36L1 1 GO:0032757 positive regulation of interleukin-8 production 1/504 62/18722 0.816351204464967 0.870543722655055 STAT3 1 GO:0048002 antigen processing and presentation of peptide antigen 1/504 62/18722 0.816351204464967 0.870543722655055 B2M 1 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 1/504 62/18722 0.816351204464967 0.870543722655055 EPS8 1 GO:1903362 regulation of cellular protein catabolic process 5/504 255/18722 0.819944790766738 0.873663783549727 CD81/CAV1/HIPK2/MSN/PTEN 5 GO:0002704 negative regulation of leukocyte mediated immunity 1/504 63/18722 0.821311493476203 0.873663783549727 AHR 1 GO:0016239 positive regulation of macroautophagy 1/504 63/18722 0.821311493476203 0.873663783549727 DCN 1 GO:0031343 positive regulation of cell killing 1/504 63/18722 0.821311493476203 0.873663783549727 B2M 1 GO:0045143 homologous chromosome segregation 1/504 63/18722 0.821311493476203 0.873663783549727 P3H4 1 GO:0046902 regulation of mitochondrial membrane permeability 1/504 63/18722 0.821311493476203 0.873663783549727 STAT3 1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 1/504 63/18722 0.821311493476203 0.873663783549727 XBP1 1 GO:1902373 negative regulation of mRNA catabolic process 1/504 63/18722 0.821311493476203 0.873663783549727 ZFP36 1 GO:0016050 vesicle organization 6/504 300/18722 0.821551101706635 0.873663783549727 ZEB2/CAV1/SEC31A/SEC23A/CAV2/SEC24D 6 GO:0050806 positive regulation of synaptic transmission 3/504 164/18722 0.821730574792032 0.873663783549727 LAMA2/NPTN/PTEN 3 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 3/504 164/18722 0.821730574792032 0.873663783549727 CAV1/HIPK2/PTEN 3 GO:2001242 regulation of intrinsic apoptotic signaling pathway 3/504 164/18722 0.821730574792032 0.873663783549727 CAV1/HSPB1/XBP1 3 GO:0006749 glutathione metabolic process 1/504 64/18722 0.826138065494424 0.876169757720942 GSTM3 1 GO:0017156 calcium-ion regulated exocytosis 1/504 64/18722 0.826138065494424 0.876169757720942 MYH9 1 GO:0030104 water homeostasis 1/504 64/18722 0.826138065494424 0.876169757720942 EXT1 1 GO:0030858 positive regulation of epithelial cell differentiation 1/504 64/18722 0.826138065494424 0.876169757720942 VEZF1 1 GO:0046888 negative regulation of hormone secretion 1/504 64/18722 0.826138065494424 0.876169757720942 MAP4K4 1 GO:0048247 lymphocyte chemotaxis 1/504 64/18722 0.826138065494424 0.876169757720942 GAS6 1 GO:0070542 response to fatty acid 1/504 64/18722 0.826138065494424 0.876169757720942 FOXO1 1 GO:1903018 regulation of glycoprotein metabolic process 1/504 64/18722 0.826138065494424 0.876169757720942 RAMP1 1 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 1/504 64/18722 0.826138065494424 0.876169757720942 HIPK2 1 GO:1903409 reactive oxygen species biosynthetic process 1/504 64/18722 0.826138065494424 0.876169757720942 STAT3 1 GO:0051225 spindle assembly 2/504 117/18722 0.826956628044883 0.876820265914587 FLNA/MAP9 2 GO:0051656 establishment of organelle localization 8/504 390/18722 0.827874832586294 0.877576075326528 MAP1B/MYO1B/ITGB1/MYH9/SPRY1/ACTN4/MAP4/ARMCX3 8 GO:0035418 protein localization to synapse 1/504 65/18722 0.830834518221984 0.878969026086293 HSPB1 1 GO:0038034 signal transduction in absence of ligand 1/504 65/18722 0.830834518221984 0.878969026086293 FGFR1 1 GO:0043489 RNA stabilization 1/504 65/18722 0.830834518221984 0.878969026086293 ZFP36 1 GO:0046503 glycerolipid catabolic process 1/504 65/18722 0.830834518221984 0.878969026086293 LIPG 1 GO:0061512 protein localization to cilium 1/504 65/18722 0.830834518221984 0.878969026086293 ARL3 1 GO:0071677 positive regulation of mononuclear cell migration 1/504 65/18722 0.830834518221984 0.878969026086293 GAS6 1 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 1/504 65/18722 0.830834518221984 0.878969026086293 FGFR1 1 GO:1902475 L-alpha-amino acid transmembrane transport 1/504 65/18722 0.830834518221984 0.878969026086293 ITGB1 1 GO:0016482 cytosolic transport 3/504 168/18722 0.834001505820629 0.881932862741309 FLNA/PREPL/MSN 3 GO:0031398 positive regulation of protein ubiquitination 2/504 119/18722 0.834048841174264 0.881932862741309 CAV1/PTEN 2 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 1/504 66/18722 0.835404352751443 0.882056535534203 NBN 1 GO:0016444 somatic cell DNA recombination 1/504 66/18722 0.835404352751443 0.882056535534203 NBN 1 GO:0042093 T-helper cell differentiation 1/504 66/18722 0.835404352751443 0.882056535534203 STAT3 1 GO:1902476 chloride transmembrane transport 1/504 66/18722 0.835404352751443 0.882056535534203 PCYOX1 1 GO:1905953 negative regulation of lipid localization 1/504 66/18722 0.835404352751443 0.882056535534203 THBS1 1 GO:2000272 negative regulation of signaling receptor activity 1/504 66/18722 0.835404352751443 0.882056535534203 PTEN 1 GO:0072655 establishment of protein localization to mitochondrion 2/504 120/18722 0.837495713767178 0.884046241335759 TSPO/TOMM7 2 GO:0006513 protein monoubiquitination 1/504 67/18722 0.839850976154814 0.885002027400621 PCGF5 1 GO:0006879 cellular iron ion homeostasis 1/504 67/18722 0.839850976154814 0.885002027400621 CYBRD1 1 GO:0016445 somatic diversification of immunoglobulins 1/504 67/18722 0.839850976154814 0.885002027400621 NBN 1 GO:0046635 positive regulation of alpha-beta T cell activation 1/504 67/18722 0.839850976154814 0.885002027400621 CD81 1 GO:0050435 amyloid-beta metabolic process 1/504 67/18722 0.839850976154814 0.885002027400621 ROCK2 1 GO:0061180 mammary gland epithelium development 1/504 67/18722 0.839850976154814 0.885002027400621 WNT2 1 GO:1902117 positive regulation of organelle assembly 1/504 67/18722 0.839850976154814 0.885002027400621 MSN 1 GO:0048469 cell maturation 3/504 171/18722 0.842722067605842 0.887808529309607 PDE3A/AXL/EDNRB 3 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 1/504 68/18722 0.844177704003539 0.888266251024081 STAT3 1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 1/504 68/18722 0.844177704003539 0.888266251024081 IL6ST 1 GO:0042987 amyloid precursor protein catabolic process 1/504 68/18722 0.844177704003539 0.888266251024081 ROCK2 1 GO:0061912 selective autophagy 1/504 68/18722 0.844177704003539 0.888266251024081 TOMM7 1 GO:0019730 antimicrobial humoral response 2/504 122/18722 0.844195938546406 0.888266251024081 SPON2/RARRES2 2 GO:0002221 pattern recognition receptor signaling pathway 3/504 172/18722 0.845539595822152 0.889461027313652 CAV1/PJA2/RAB11FIP2 3 GO:0050852 T cell receptor signaling pathway 2/504 123/18722 0.847451253115546 0.890702926421236 THY1/CD81 2 GO:0002287 alpha-beta T cell activation involved in immune response 1/504 69/18722 0.84838776282107 0.890702926421236 STAT3 1 GO:0002293 alpha-beta T cell differentiation involved in immune response 1/504 69/18722 0.84838776282107 0.890702926421236 STAT3 1 GO:0033344 cholesterol efflux 1/504 69/18722 0.84838776282107 0.890702926421236 CAV1 1 GO:0034605 cellular response to heat 1/504 69/18722 0.84838776282107 0.890702926421236 THBS1 1 GO:0050688 regulation of defense response to virus 1/504 69/18722 0.84838776282107 0.890702926421236 HTRA1 1 GO:0050805 negative regulation of synaptic transmission 1/504 69/18722 0.84838776282107 0.890702926421236 PTEN 1 GO:0051966 regulation of synaptic transmission, glutamatergic 1/504 69/18722 0.84838776282107 0.890702926421236 MEF2C 1 GO:0006605 protein targeting 6/504 314/18722 0.852640679004023 0.894948076979658 LTBP2/TSPO/CHM/STOM/TOMM7/SEC62 6 GO:0051052 regulation of DNA metabolic process 7/504 359/18722 0.853334074986322 0.895455919061039 PDGFRB/PARM1/HGF/ATRX/BMPR2/NBN/KMT2A 7 GO:0022900 electron transport chain 3/504 175/18722 0.853731087454701 0.895481037107193 COX4I2/COX7A1/DHRS3 3 GO:0060294 cilium movement involved in cell motility 2/504 125/18722 0.853777146074118 0.895481037107193 ADCY3/ATP2B4 2 GO:0032722 positive regulation of chemokine production 1/504 71/18722 0.856470348474283 0.898085349455365 EGR1 1 GO:0009101 glycoprotein biosynthetic process 6/504 317/18722 0.858693348488016 0.900195455860964 RAMP1/EXT1/DSEL/UGDH/MAN2A1/BMPR2 6 GO:0051648 vesicle localization 3/504 177/18722 0.858979432829709 0.900274495089857 MYO1B/ACTN4/PTEN 3 GO:0034655 nucleobase-containing compound catabolic process 8/504 407/18722 0.860323407922343 0.901046781371768 PDE8B/ENPP1/VIM/KCNQ1OT1/ZFP36L1/ZFP36/ROCK2/TNRC6B 8 GO:0050709 negative regulation of protein secretion 1/504 72/18722 0.860348904281959 0.901046781371768 MAP4K4 1 GO:0070227 lymphocyte apoptotic process 1/504 72/18722 0.860348904281959 0.901046781371768 PTEN 1 GO:0015980 energy derivation by oxidation of organic compounds 6/504 318/18722 0.86066495554085 0.901156911302634 COX4I2/ENPP1/COX7A1/IL6ST/DYRK2/IGF2 6 GO:0002703 regulation of leukocyte mediated immunity 4/504 226/18722 0.861294142632601 0.901594774980183 CD81/IL1R1/B2M/AHR 4 GO:0002637 regulation of immunoglobulin production 1/504 73/18722 0.86412285346383 0.903670326199448 XBP1 1 GO:0009166 nucleotide catabolic process 1/504 73/18722 0.86412285346383 0.903670326199448 PDE8B 1 GO:0032456 endocytic recycling 1/504 73/18722 0.86412285346383 0.903670326199448 EHD2 1 GO:0051937 catecholamine transport 1/504 73/18722 0.86412285346383 0.903670326199448 ACTB 1 GO:0007127 meiosis I 2/504 129/18722 0.865716764466714 0.905115667865493 HSPA2/P3H4 2 GO:0010822 positive regulation of mitochondrion organization 1/504 74/18722 0.867795011855928 0.906623003828943 DCN 1 GO:0046470 phosphatidylcholine metabolic process 1/504 74/18722 0.867795011855928 0.906623003828943 PLA2G2A 1 GO:1901568 fatty acid derivative metabolic process 1/504 74/18722 0.867795011855928 0.906623003828943 ELOVL5 1 GO:0051028 mRNA transport 2/504 130/18722 0.868558791337719 0.907199148224413 ZFP36L1/ZFP36 2 GO:0016197 endosomal transport 4/504 230/18722 0.870175286914641 0.908443440260508 EHD2/PREPL/ITSN1/TMEM50B 4 GO:0045055 regulated exocytosis 4/504 230/18722 0.870175286914641 0.908443440260508 MYH9/PREPL/CTBP2/RAB11FIP2 4 GO:0002292 T cell differentiation involved in immune response 1/504 75/18722 0.871368119643605 0.909022454891876 STAT3 1 GO:1902369 negative regulation of RNA catabolic process 1/504 75/18722 0.871368119643605 0.909022454891876 ZFP36 1 GO:1903363 negative regulation of cellular protein catabolic process 1/504 75/18722 0.871368119643605 0.909022454891876 HIPK2 1 GO:0007281 germ cell development 5/504 278/18722 0.872113846627482 0.909578341869473 PDE3A/MDK/HSPA2/FNDC3A/SMAD5 5 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 2/504 133/18722 0.876756699391445 0.914197505246375 CAV1/PTEN 2 GO:0002200 somatic diversification of immune receptors 1/504 77/18722 0.878227778010403 0.9152847062045 NBN 1 GO:0032418 lysosome localization 1/504 77/18722 0.878227778010403 0.9152847062045 MYH9 1 GO:0032147 activation of protein kinase activity 2/504 134/18722 0.879382949269529 0.916265140753157 GAS6/TGFB2 2 GO:1903532 positive regulation of secretion by cell 5/504 282/18722 0.879745374397572 0.916419303949495 CAMK2N1/TGFB2/SOX4/ITSN1/ADAM9 5 GO:1902115 regulation of organelle assembly 3/504 186/18722 0.88060531838328 0.917091524604376 GSN/MAP4/MSN 3 GO:0090559 regulation of membrane permeability 1/504 78/18722 0.881519448693307 0.917819835347588 STAT3 1 GO:0061982 meiosis I cell cycle process 2/504 135/18722 0.881957485840756 0.918052213641304 HSPA2/P3H4 2 GO:0019439 aromatic compound catabolic process 9/504 467/18722 0.885363797635911 0.92137347961477 PDE8B/ENPP1/VIM/KCNQ1OT1/MAOA/ZFP36L1/ZFP36/ROCK2/TNRC6B 9 GO:0060078 regulation of postsynaptic membrane potential 2/504 137/18722 0.886954905424826 0.922804555851055 MEF2C/PTEN 2 GO:1901264 carbohydrate derivative transport 1/504 80/18722 0.887838761537703 0.923499276545912 SLC25A24 1 GO:0001539 cilium or flagellum-dependent cell motility 2/504 138/18722 0.889379507824831 0.924426815114449 ADCY3/ATP2B4 2 GO:0060285 cilium-dependent cell motility 2/504 138/18722 0.889379507824831 0.924426815114449 ADCY3/ATP2B4 2 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 2/504 138/18722 0.889379507824831 0.924426815114449 CAV1/PTEN 2 GO:0050851 antigen receptor-mediated signaling pathway 4/504 240/18722 0.89026474442337 0.925121900029441 THY1/MEF2C/CD81/CMTM3 4 GO:0006096 glycolytic process 1/504 81/18722 0.89087112202397 0.925526940045812 STAT3 1 GO:0001910 regulation of leukocyte mediated cytotoxicity 1/504 82/18722 0.893821658717277 0.927915439188271 B2M 1 GO:0006757 ATP generation from ADP 1/504 82/18722 0.893821658717277 0.927915439188271 STAT3 1 GO:0016575 histone deacetylation 1/504 82/18722 0.893821658717277 0.927915439188271 HDAC7 1 GO:0046165 alcohol biosynthetic process 2/504 140/18722 0.894084723715081 0.927963085847593 CYB5R3/ACLY 2 GO:0006119 oxidative phosphorylation 2/504 141/18722 0.896366998105556 0.92976640961072 COX4I2/COX7A1 2 GO:0016241 regulation of macroautophagy 2/504 141/18722 0.896366998105556 0.92976640961072 DCN/QSOX1 2 GO:0043367 CD4-positive, alpha-beta T cell differentiation 1/504 83/18722 0.89669257524123 0.92976640961072 STAT3 1 GO:0050886 endocrine process 1/504 83/18722 0.89669257524123 0.92976640961072 AGTR1 1 GO:0046467 membrane lipid biosynthetic process 2/504 142/18722 0.898603474174606 0.931521747973821 PLPP1/ELOVL5 2 GO:0006835 dicarboxylic acid transport 1/504 84/18722 0.899486015987966 0.93153265785666 ITGB1 1 GO:0009953 dorsal/ventral pattern formation 1/504 84/18722 0.899486015987966 0.93153265785666 AIDA 1 GO:0015844 monoamine transport 1/504 84/18722 0.899486015987966 0.93153265785666 ACTB 1 GO:0098586 cellular response to virus 1/504 84/18722 0.899486015987966 0.93153265785666 EXT1 1 GO:0006865 amino acid transport 2/504 143/18722 0.90079495744474 0.932662188796068 ITGB1/SLC38A2 2 GO:0008380 RNA splicing 8/504 434/18722 0.90155525591417 0.93322325787821 SLC38A2/MBNL2/MBNL1/AHNAK/DDX17/ZRANB2/PIK3R1/RBFOX2 8 GO:0044070 regulation of anion transport 1/504 87/18722 0.907422072086403 0.939068664089417 ITGB1 1 GO:0050829 defense response to Gram-negative bacterium 1/504 88/18722 0.909925923745564 0.941203939037713 RARRES2 1 GO:0070098 chemokine-mediated signaling pathway 1/504 88/18722 0.909925923745564 0.941203939037713 SLIT3 1 GO:0042742 defense response to bacterium 6/504 350/18722 0.912680203294516 0.943824421267538 PLA2G2A/SPON2/RARRES2/ADAMTS5/NOTCH2/ISG15 6 GO:0006839 mitochondrial transport 4/504 254/18722 0.913804813663461 0.944758763315744 TSPO/STAT3/TOMM7/SLC25A24 4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1/504 90/18722 0.914732683568826 0.945260642536782 CAV1 1 GO:0046031 ADP metabolic process 1/504 90/18722 0.914732683568826 0.945260642536782 STAT3 1 GO:0046700 heterocycle catabolic process 8/504 445/18722 0.915142477219122 0.945374657019204 PDE8B/ENPP1/VIM/KCNQ1OT1/ZFP36L1/ZFP36/ROCK2/TNRC6B 8 GO:0006887 exocytosis 6/504 352/18722 0.9152855034141 0.945374657019204 SYTL2/MYH9/PREPL/ITSN1/CTBP2/RAB11FIP2 6 GO:0006885 regulation of pH 1/504 91/18722 0.91703918461441 0.9460425967787 EDNRB 1 GO:0042147 retrograde transport, endosome to Golgi 1/504 91/18722 0.91703918461441 0.9460425967787 PREPL 1 GO:0051952 regulation of amine transport 1/504 91/18722 0.91703918461441 0.9460425967787 ITGB1 1 GO:0051983 regulation of chromosome segregation 1/504 91/18722 0.91703918461441 0.9460425967787 SMC6 1 GO:0098661 inorganic anion transmembrane transport 1/504 91/18722 0.91703918461441 0.9460425967787 PCYOX1 1 GO:0034502 protein localization to chromosome 1/504 92/18722 0.919283414712329 0.947900104021666 ATRX 1 GO:1903312 negative regulation of mRNA metabolic process 1/504 92/18722 0.919283414712329 0.947900104021666 ZFP36 1 GO:1901361 organic cyclic compound catabolic process 9/504 495/18722 0.919921924050349 0.948329645709805 PDE8B/ENPP1/VIM/KCNQ1OT1/MAOA/ZFP36L1/ZFP36/ROCK2/TNRC6B 9 GO:0032088 negative regulation of NF-kappaB transcription factor activity 1/504 93/18722 0.921467051802237 0.949464362756441 TMSB4X 1 GO:0045132 meiotic chromosome segregation 1/504 93/18722 0.921467051802237 0.949464362756441 P3H4 1 GO:0044270 cellular nitrogen compound catabolic process 8/504 451/18722 0.921855115447413 0.949635223796238 PDE8B/ENPP1/VIM/KCNQ1OT1/ZFP36L1/ZFP36/ROCK2/TNRC6B 8 GO:0007605 sensory perception of sound 2/504 154/18722 0.922151984673936 0.949712082552839 COL1A1/CCDC50 2 GO:0048704 embryonic skeletal system morphogenesis 1/504 94/18722 0.923591728698027 0.950965652223294 PDGFRA 1 GO:0006665 sphingolipid metabolic process 2/504 155/18722 0.923862692941617 0.951015487096971 PLPP1/ELOVL5 2 GO:0032479 regulation of type I interferon production 1/504 95/18722 0.925659034299068 0.952176469321117 ISG15 1 GO:0032606 type I interferon production 1/504 95/18722 0.925659034299068 0.952176469321117 ISG15 1 GO:0042982 amyloid precursor protein metabolic process 1/504 95/18722 0.925659034299068 0.952176469321117 ROCK2 1 GO:0007034 vacuolar transport 2/504 157/18722 0.927178439211183 0.953509860589503 RHOB/TMEM50B 2 GO:0002768 immune response-regulating cell surface receptor signaling pathway 5/504 315/18722 0.929102589973456 0.955258750470783 THY1/MEF2C/CD81/CMTM3/SOS1 5 GO:1990868 response to chemokine 1/504 97/18722 0.929627674682899 0.955338877806645 SLIT3 1 GO:1990869 cellular response to chemokine 1/504 97/18722 0.929627674682899 0.955338877806645 SLIT3 1 GO:0002377 immunoglobulin production 3/504 216/18722 0.932920195486956 0.958299288698066 B2M/XBP1/NBN 3 GO:0006165 nucleoside diphosphate phosphorylation 1/504 99/18722 0.933384849869318 0.958299288698066 STAT3 1 GO:0015837 amine transport 1/504 99/18722 0.933384849869318 0.958299288698066 ITGB1 1 GO:0051650 establishment of vesicle localization 2/504 161/18722 0.933405485504646 0.958299288698066 MYO1B/ACTN4 2 GO:0050657 nucleic acid transport 2/504 163/18722 0.93632685117706 0.960606154881051 ZFP36L1/ZFP36 2 GO:0050658 RNA transport 2/504 163/18722 0.93632685117706 0.960606154881051 ZFP36L1/ZFP36 2 GO:0061025 membrane fusion 2/504 163/18722 0.93632685117706 0.960606154881051 GAS6/CAV2 2 GO:0046939 nucleotide phosphorylation 1/504 101/18722 0.93694180637292 0.961006322283122 STAT3 1 GO:0031503 protein-containing complex localization 3/504 220/18722 0.938023709175155 0.961406863746419 HIP1/ARL3/NPTN 3 GO:0002764 immune response-regulating signaling pathway 8/504 468/18722 0.938446862384856 0.961406863746419 THY1/MEF2C/CD81/CAV1/CMTM3/PJA2/RAB11FIP2/SOS1 8 GO:0006672 ceramide metabolic process 1/504 102/18722 0.938648553034648 0.961406863746419 PLPP1 1 GO:0034308 primary alcohol metabolic process 1/504 102/18722 0.938648553034648 0.961406863746419 DHRS3 1 GO:1990542 mitochondrial transmembrane transport 1/504 102/18722 0.938648553034648 0.961406863746419 TOMM7 1 GO:0007286 spermatid development 2/504 165/18722 0.939126563681726 0.961406863746419 HSPA2/FNDC3A 2 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 3/504 221/18722 0.939242352905733 0.961406863746419 CAV1/HIPK2/PTEN 3 GO:0009135 purine nucleoside diphosphate metabolic process 1/504 103/18722 0.940309193704387 0.961406863746419 STAT3 1 GO:0009179 purine ribonucleoside diphosphate metabolic process 1/504 103/18722 0.940309193704387 0.961406863746419 STAT3 1 GO:0019233 sensory perception of pain 1/504 103/18722 0.940309193704387 0.961406863746419 EDNRB 1 GO:0030004 cellular monovalent inorganic cation homeostasis 1/504 103/18722 0.940309193704387 0.961406863746419 SLC8A1 1 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 1/504 103/18722 0.940309193704387 0.961406863746419 CAV1 1 GO:0015931 nucleobase-containing compound transport 3/504 222/18722 0.940438824023361 0.961406863746419 ZFP36L1/ZFP36/SLC25A24 3 GO:0051236 establishment of RNA localization 2/504 166/18722 0.940482258474147 0.961406863746419 ZFP36L1/ZFP36 2 GO:0022600 digestive system process 1/504 104/18722 0.941924971478327 0.962651376016956 LIMA1 1 GO:0006486 protein glycosylation 3/504 226/18722 0.945009986407008 0.964667768437539 RAMP1/EXT1/MAN2A1 3 GO:0043413 macromolecule glycosylation 3/504 226/18722 0.945009986407008 0.964667768437539 RAMP1/EXT1/MAN2A1 3 GO:0006090 pyruvate metabolic process 1/504 106/18722 0.945026744366847 0.964667768437539 STAT3 1 GO:0006906 vesicle fusion 1/504 106/18722 0.945026744366847 0.964667768437539 CAV2 1 GO:0009185 ribonucleoside diphosphate metabolic process 1/504 106/18722 0.945026744366847 0.964667768437539 STAT3 1 GO:0034440 lipid oxidation 1/504 108/18722 0.9479631634525 0.967043764502843 APOD 1 GO:0048515 spermatid differentiation 2/504 172/18722 0.94803330903403 0.967043764502843 HSPA2/FNDC3A 2 GO:1901136 carbohydrate derivative catabolic process 2/504 172/18722 0.94803330903403 0.967043764502843 ADAMTS9/PDE8B 2 GO:0006520 cellular amino acid metabolic process 4/504 284/18722 0.949718249696225 0.968531284236747 ATP2B4/DDAH2/GLS/PLOD2 4 GO:0090174 organelle membrane fusion 1/504 110/18722 0.950743027066268 0.969345014233873 CAV2 1 GO:0003341 cilium movement 2/504 175/18722 0.951457851442247 0.96961111357327 ADCY3/ATP2B4 2 GO:0050954 sensory perception of mechanical stimulus 2/504 175/18722 0.951457851442247 0.96961111357327 COL1A1/CCDC50 2 GO:0015718 monocarboxylic acid transport 1/504 111/18722 0.952076871594454 0.970010603796639 PLA2G2A 1 GO:0001676 long-chain fatty acid metabolic process 1/504 112/18722 0.953374666270527 0.970655436634393 ELOVL5 1 GO:0046632 alpha-beta T cell differentiation 1/504 112/18722 0.953374666270527 0.970655436634393 STAT3 1 GO:0006631 fatty acid metabolic process 6/504 390/18722 0.953391263176819 0.970655436634393 LIPG/CAV1/LPGAT1/XBP1/ELOVL5/ACLY 6 GO:0001578 microtubule bundle formation 1/504 113/18722 0.954637383530046 0.971092555449684 MAP1B 1 GO:0000209 protein polyubiquitination 3/504 236/18722 0.955051593321279 0.971092555449684 IFI27/TTC3/UBE2E3 3 GO:0046395 carboxylic acid catabolic process 3/504 236/18722 0.955051593321279 0.971092555449684 ATP2B4/DDAH2/GLS 3 GO:0006091 generation of precursor metabolites and energy 8/504 490/18722 0.955289882650254 0.971092555449684 COX4I2/ENPP1/COX7A1/IL6ST/DYRK2/IGF2/STAT3/DHRS3 8 GO:0002429 immune response-activating cell surface receptor signaling pathway 4/504 291/18722 0.955830332947945 0.971092555449684 THY1/MEF2C/CD81/CMTM3 4 GO:0002757 immune response-activating signal transduction 4/504 291/18722 0.955830332947945 0.971092555449684 THY1/MEF2C/CD81/CMTM3 4 GO:0007041 lysosomal transport 1/504 114/18722 0.955865969628217 0.971092555449684 RHOB 1 GO:1901800 positive regulation of proteasomal protein catabolic process 1/504 114/18722 0.955865969628217 0.971092555449684 CAV1 1 GO:1904892 regulation of receptor signaling pathway via STAT 1/504 114/18722 0.955865969628217 0.971092555449684 CAV1 1 GO:0090630 activation of GTPase activity 1/504 115/18722 0.95706134534336 0.972075856584782 ARHGAP42 1 GO:0007006 mitochondrial membrane organization 1/504 116/18722 0.958224406661517 0.972448853856269 STAT3 1 GO:0031123 RNA 3'-end processing 1/504 116/18722 0.958224406661517 0.972448853856269 ZFP36L1 1 GO:0033559 unsaturated fatty acid metabolic process 1/504 116/18722 0.958224406661517 0.972448853856269 ELOVL5 1 GO:0016054 organic acid catabolic process 3/504 240/18722 0.958566480796303 0.972448853856269 ATP2B4/DDAH2/GLS 3 GO:0070085 glycosylation 3/504 240/18722 0.958566480796303 0.972448853856269 RAMP1/EXT1/MAN2A1 3 GO:0033044 regulation of chromosome organization 2/504 187/18722 0.96312061723129 0.976837027635723 ATRX/NBN 2 GO:0015711 organic anion transport 5/504 354/18722 0.963606021136608 0.977097420103636 PLA2G2A/MGST1/ITGB1/SLC38A2/SLC25A24 5 GO:0001906 cell killing 2/504 188/18722 0.963960712961844 0.977225178288484 CFH/B2M 2 GO:0015849 organic acid transport 4/504 303/18722 0.96473948006806 0.977594333156573 PLA2G2A/THBS1/ITGB1/SLC38A2 4 GO:0009060 aerobic respiration 2/504 189/18722 0.964782425209752 0.977594333156573 COX4I2/COX7A1 2 GO:0006325 chromatin organization 6/504 409/18722 0.965926040465105 0.978521093150165 CHD9/ACTB/NR3C1/KMT2E/ZMYND11/ATRX 6 GO:0001909 leukocyte mediated cytotoxicity 1/504 124/18722 0.966465427315047 0.978603500217345 B2M 1 GO:0009132 nucleoside diphosphate metabolic process 1/504 124/18722 0.966465427315047 0.978603500217345 STAT3 1 GO:0006302 double-strand break repair 3/504 251/18722 0.96695003531321 0.978862236648507 REV3L/SMC6/NBN 3 GO:0006334 nucleosome assembly 1/504 129/18722 0.970770055943047 0.982496553539706 ATRX 1 GO:0006352 DNA-templated transcription, initiation 1/504 130/18722 0.971562391327584 0.983065616420262 JUN 1 GO:0045089 positive regulation of innate immune response 1/504 131/18722 0.972333290357861 0.983538699365606 IFI16 1 GO:0043414 macromolecule methylation 4/504 316/18722 0.972490288981906 0.983538699365606 NNMT/KMT2E/ATRX/KMT2A 4 GO:0090305 nucleic acid phosphodiester bond hydrolysis 3/504 261/18722 0.973159679606193 0.983699552428123 ENPP1/ENDOD1/ZFP36 3 GO:0006403 RNA localization 2/504 201/18722 0.973339973710766 0.983699552428123 ZFP36L1/ZFP36 2 GO:0065004 protein-DNA complex assembly 2/504 201/18722 0.973339973710766 0.983699552428123 TCF4/ATRX 2 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1/504 134/18722 0.974523080056755 0.983997290732312 CAV1 1 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 4/504 320/18722 0.974534367946582 0.983997290732312 MBNL2/MBNL1/DDX17/RBFOX2 4 GO:0000398 mRNA splicing, via spliceosome 4/504 320/18722 0.974534367946582 0.983997290732312 MBNL2/MBNL1/DDX17/RBFOX2 4 GO:0006643 membrane lipid metabolic process 2/504 203/18722 0.974555706618101 0.983997290732312 PLPP1/ELOVL5 2 GO:0009581 detection of external stimulus 1/504 135/18722 0.975213868073292 0.984429212916886 PKD2 1 GO:0044282 small molecule catabolic process 5/504 376/18722 0.975450847198777 0.984435869173447 INPP4B/ATP2B4/DDAH2/GLS/PTEN 5 GO:1903305 regulation of regulated secretory pathway 1/504 136/18722 0.975885962036334 0.98464243583973 PREPL 1 GO:0000375 RNA splicing, via transesterification reactions 4/504 324/18722 0.976435482409773 0.98483711378603 MBNL2/MBNL1/DDX17/RBFOX2 4 GO:0007586 digestion 1/504 137/18722 0.97653986686436 0.98483711378603 LIMA1 1 GO:0009582 detection of abiotic stimulus 1/504 138/18722 0.977176073864649 0.985246192454847 PKD2 1 GO:0015748 organophosphate ester transport 1/504 140/18722 0.978397293742539 0.986244783241772 SLC25A24 1 GO:0048284 organelle fusion 1/504 141/18722 0.978983224425661 0.986543112237157 CAV2 1 GO:0046942 carboxylic acid transport 3/504 273/18722 0.979155005616144 0.986543112237157 PLA2G2A/ITGB1/SLC38A2 3 GO:1903531 negative regulation of secretion by cell 1/504 147/18722 0.982180317653838 0.989357967311374 MAP4K4 1 GO:0031497 chromatin assembly 1/504 151/18722 0.984037184321609 0.990994788735855 ATRX 1 GO:0007059 chromosome segregation 4/504 346/18722 0.984719772425334 0.991448536186016 NR3C1/P3H4/SMC6/ATRX 4 GO:0016052 carbohydrate catabolic process 1/504 154/18722 0.985301947127796 0.991773158259811 STAT3 1 GO:0071103 DNA conformation change 3/504 290/18722 0.985506395967975 0.991773158259811 CHD9/ATRX/NBN 3 GO:0045333 cellular respiration 2/504 230/18722 0.986544304736566 0.992583897843029 COX4I2/COX7A1 2 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 5/504 412/18722 0.987414313909225 0.993225368016506 IFI27/CAV1/CLOCK/HSP90B1/WWTR1 5 GO:0032259 methylation 4/504 364/18722 0.989360753414484 0.994424413687805 NNMT/KMT2E/ATRX/KMT2A 4 GO:0006310 DNA recombination 3/504 305/18722 0.989532100124015 0.994424413687805 REV3L/SMC6/NBN 3 GO:0071824 protein-DNA complex subunit organization 2/504 241/18722 0.989655527375417 0.994424413687805 TCF4/ATRX 2 GO:0034728 nucleosome organization 1/504 167/18722 0.989723546927348 0.994424413687805 ATRX 1 GO:0000070 mitotic sister chromatid segregation 1/504 168/18722 0.990002680980089 0.994424413687805 ATRX 1 GO:0002833 positive regulation of response to biotic stimulus 1/504 168/18722 0.990002680980089 0.994424413687805 IFI16 1 GO:0098656 anion transmembrane transport 2/504 245/18722 0.990602990300754 0.994753087362716 ITGB1/PCYOX1 2 GO:0051048 negative regulation of secretion 1/504 171/18722 0.990795492585003 0.994753087362716 MAP4K4 1 GO:0006333 chromatin assembly or disassembly 1/504 177/18722 0.992197803202305 0.995879291578902 ATRX 1 GO:0016042 lipid catabolic process 3/504 320/18722 0.992470486606928 0.995879291578902 PLA2G2A/RARRES2/LIPG 3 GO:0006338 chromatin remodeling 2/504 255/18722 0.992616405999191 0.995879291578902 ACTB/ATRX 2 GO:0061136 regulation of proteasomal protein catabolic process 1/504 187/18722 0.994077226308467 0.997110795308938 CAV1 1 GO:0006323 DNA packaging 1/504 199/18722 0.995745891419291 0.998186229950326 ATRX 1 GO:0098813 nuclear chromosome segregation 2/504 281/18722 0.996079269374015 0.998186229950326 P3H4/ATRX 2 GO:0000819 sister chromatid segregation 1/504 202/18722 0.996083801663513 0.998186229950326 ATRX 1 GO:0017157 regulation of exocytosis 1/504 202/18722 0.996083801663513 0.998186229950326 PREPL 1 GO:0044242 cellular lipid catabolic process 1/504 214/18722 0.997187904579445 0.998884649295865 LIPG 1 GO:0010498 proteasomal protein catabolic process 5/504 490/18722 0.997283232850641 0.998884649295865 IFI27/CAV1/CLOCK/HSP90B1/WWTR1 5 GO:0042254 ribosome biogenesis 2/504 299/18722 0.997482049741506 0.998884649295865 DDX17/PTEN 2 GO:0006364 rRNA processing 1/504 225/18722 0.997924615548678 0.999093693120783 DDX17 1 GO:0016072 rRNA metabolic process 1/504 236/18722 0.998468604064273 0.999404156750208 DDX17 1 GO:0034470 ncRNA processing 2/504 395/18722 0.999774450059398 0.99999662707755 DDX17/STAT3 2 GO:0034660 ncRNA metabolic process 3/504 485/18722 0.999836200830237 0.99999662707755 KCNQ1OT1/DDX17/STAT3 3 GO:0022613 ribonucleoprotein complex biogenesis 2/504 463/18722 0.99996078551783 0.99999662707755 DDX17/PTEN 2 GO:0007608 sensory perception of smell 1/504 456/18722 0.99999662707755 0.99999662707755 ADCY3 1