ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0090130	tissue migration	80/988	365/18722	2.27854725057652e-28	6.76593339614287e-25	SPARC/CDH5/EDN1/KDR/MMRN2/ACVRL1/MEOX2/CLEC14A/TEK/SOX18/VEGFC/RHOJ/LOXL2/CEACAM1/FOXF1/ADGRA2/ITGA2/ENPP2/EFNB2/MEF2C/PLXND1/BMPR2/PRCP/FGFR1/SCARB1/FOXP1/ETS1/ANGPT2/PRKCE/MACF1/THBS1/ANGPT1/HDAC7/PPM1F/ID1/NOTCH1/FSTL1/VASH1/TGFBR2/ITGB1/RHOB/TMSB4X/RGCC/PXN/PIK3R3/NRP1/PDGFB/SASH1/MAP3K3/PKN1/TGFB1/RIN2/PLPP3/AKT3/MYH9/PIK3CA/KLF4/PTEN/RRAS/RHOA/HIF1A/PTPRM/PIK3C2A/MAP4K4/GATA2/PTPRG/NR2F2/PKN2/RTN4/STARD13/ATP2B4/EMP2/SP100/RAB11A/ROCK2/ROCK1/SYNJ2BP/PTK2/DOCK1/PLK2	80
GO:0010631	epithelial cell migration	79/988	357/18722	2.54741468228271e-28	6.76593339614287e-25	SPARC/CDH5/EDN1/KDR/MMRN2/ACVRL1/MEOX2/CLEC14A/TEK/SOX18/VEGFC/RHOJ/LOXL2/CEACAM1/ADGRA2/ITGA2/ENPP2/EFNB2/MEF2C/PLXND1/BMPR2/PRCP/FGFR1/SCARB1/FOXP1/ETS1/ANGPT2/PRKCE/MACF1/THBS1/ANGPT1/HDAC7/PPM1F/ID1/NOTCH1/FSTL1/VASH1/TGFBR2/ITGB1/RHOB/TMSB4X/RGCC/PXN/PIK3R3/NRP1/PDGFB/SASH1/MAP3K3/PKN1/TGFB1/RIN2/PLPP3/AKT3/MYH9/PIK3CA/KLF4/PTEN/RRAS/RHOA/HIF1A/PTPRM/PIK3C2A/MAP4K4/GATA2/PTPRG/NR2F2/PKN2/RTN4/STARD13/ATP2B4/EMP2/SP100/RAB11A/ROCK2/ROCK1/SYNJ2BP/PTK2/DOCK1/PLK2	79
GO:0090132	epithelium migration	79/988	360/18722	4.62182359728006e-28	8.18370898291723e-25	SPARC/CDH5/EDN1/KDR/MMRN2/ACVRL1/MEOX2/CLEC14A/TEK/SOX18/VEGFC/RHOJ/LOXL2/CEACAM1/ADGRA2/ITGA2/ENPP2/EFNB2/MEF2C/PLXND1/BMPR2/PRCP/FGFR1/SCARB1/FOXP1/ETS1/ANGPT2/PRKCE/MACF1/THBS1/ANGPT1/HDAC7/PPM1F/ID1/NOTCH1/FSTL1/VASH1/TGFBR2/ITGB1/RHOB/TMSB4X/RGCC/PXN/PIK3R3/NRP1/PDGFB/SASH1/MAP3K3/PKN1/TGFB1/RIN2/PLPP3/AKT3/MYH9/PIK3CA/KLF4/PTEN/RRAS/RHOA/HIF1A/PTPRM/PIK3C2A/MAP4K4/GATA2/PTPRG/NR2F2/PKN2/RTN4/STARD13/ATP2B4/EMP2/SP100/RAB11A/ROCK2/ROCK1/SYNJ2BP/PTK2/DOCK1/PLK2	79
GO:0001667	ameboidal-type cell migration	91/988	475/18722	1.60402839299982e-27	2.13014970590376e-24	SPARC/CDH5/EDN1/KDR/MMRN2/ACVRL1/MEOX2/CLEC14A/TEK/SOX18/VEGFC/RHOJ/LOXL2/CEACAM1/ADGRA2/ITGA2/ENPP2/HYAL2/EFNB2/MEF2C/PLXND1/FN1/BMPR2/PRCP/FGFR1/SCARB1/FOXP1/ETS1/ANGPT2/PRKCE/MACF1/THBS1/ANGPT1/HDAC7/PPM1F/ID1/NOTCH1/FSTL1/VASH1/TGFBR2/ITGB1/RHOB/TMSB4X/RGCC/PXN/PIK3R3/NRP1/TIMP1/PDGFB/SMURF2/SASH1/MAP3K3/PKN1/EFNB1/PML/TGFB1/GJA1/RIN2/PLPP3/AKT3/MYH9/PIK3CA/KLF4/PTEN/RRAS/RHOA/HIF1A/PTPRM/PIK3C2A/MAP4K4/PHACTR4/GATA2/PTPRG/NR2F2/SEMA3F/PKN2/RTN4/STARD13/ATP2B4/EMP2/ARHGEF7/SP100/PLEC/RAB11A/ROCK2/ROCK1/SYNJ2BP/PTK2/DOCK1/AMOTL2/PLK2	91
GO:0043542	endothelial cell migration	65/988	279/18722	8.59948163466582e-25	9.13608928866896e-22	SPARC/CDH5/EDN1/KDR/MMRN2/ACVRL1/MEOX2/CLEC14A/TEK/SOX18/VEGFC/RHOJ/LOXL2/CEACAM1/ADGRA2/EFNB2/MEF2C/PLXND1/BMPR2/PRCP/FGFR1/SCARB1/FOXP1/ETS1/ANGPT2/THBS1/ANGPT1/HDAC7/ID1/NOTCH1/FSTL1/VASH1/ITGB1/RHOB/TMSB4X/RGCC/PXN/PIK3R3/NRP1/PDGFB/SASH1/MAP3K3/TGFB1/RIN2/PLPP3/AKT3/MYH9/PIK3CA/KLF4/PTEN/RRAS/RHOA/HIF1A/PTPRM/PIK3C2A/GATA2/NR2F2/STARD13/ATP2B4/EMP2/SP100/ROCK2/SYNJ2BP/PTK2/PLK2	65
GO:0003158	endothelium development	45/988	136/18722	2.75188434974297e-24	2.43633494430578e-21	PECAM1/COL15A1/CDH5/CD34/CLDN5/KDR/ACVRL1/ZEB1/HEG1/TIE1/ROBO4/SOX18/S1PR1/HOXA13/COL18A1/NOTCH4/CEACAM1/BMPR2/JAG1/PDE4D/FOXP1/MSN/PLCB1/TJP1/ID1/NOTCH1/FSTL1/RHOB/NRP1/GJA1/VEZF1/RDX/RHOA/NR2F2/VCL/CLIC4/STARD13/RAPGEF2/ADD1/F11R/GJA5/ROCK2/ROCK1/SMAD4/RAP1A	45
GO:0031589	cell-substrate adhesion	71/988	363/18722	3.34617245043507e-22	2.44416207471897e-19	VWF/CD34/KDR/ACVRL1/TEK/COL3A1/NDNF/LIMS2/FOXF1/FZD4/ITGA2/FN1/SMAD6/THSD1/ITGA5/JAG1/ITGA1/PARVB/ADAM15/ANGPT2/NID1/PRKCE/MACF1/DLC1/PEAK1/THBS1/ANGPT1/LAMB2/NEDD9/PPM1F/ID1/NOTCH1/ITGB1/PHLDB2/UTRN/PXN/NRP1/PDGFB/ACTN4/LGALS1/LIMCH1/CDK6/MDK/LAMC1/JAM3/RIN2/LIMS1/ATXN3/PTEN/FLNA/RRAS/CD36/ITGA6/RHOA/HSD17B12/FERMT2/MAP4K4/MKLN1/VCL/CTTN/EMP2/IQGAP1/CD44/ARHGEF7/PTPRA/CRK/ROCK2/ROCK1/CDC42/PTK2/DOCK1	71
GO:0010632	regulation of epithelial cell migration	63/988	292/18722	3.68096697999845e-22	2.44416207471897e-19	SPARC/EDN1/KDR/MMRN2/ACVRL1/MEOX2/TEK/VEGFC/RHOJ/CEACAM1/ADGRA2/ITGA2/ENPP2/MEF2C/BMPR2/PRCP/FGFR1/SCARB1/FOXP1/ETS1/ANGPT2/PRKCE/MACF1/THBS1/ANGPT1/HDAC7/PPM1F/NOTCH1/VASH1/TGFBR2/RHOB/TMSB4X/RGCC/NRP1/PDGFB/SASH1/MAP3K3/TGFB1/RIN2/PLPP3/AKT3/KLF4/PTEN/RRAS/RHOA/HIF1A/PTPRM/PIK3C2A/MAP4K4/GATA2/PTPRG/NR2F2/RTN4/STARD13/ATP2B4/EMP2/SP100/RAB11A/ROCK2/SYNJ2BP/PTK2/DOCK1/PLK2	63
GO:0042060	wound healing	76/988	422/18722	2.06024276435926e-21	1.21600106269738e-18	VWF/SPARC/MMRN1/CD34/EDN1/KDR/IGF1/ACVRL1/ELK3/SELP/COL3A1/MCAM/P2RY1/NDNF/CD109/NOTCH4/PROS1/CEACAM1/ITGA2/F2R/FN1/ITGA5/CAV1/TFPI2/PRCP/THBD/TFPI/SCARB1/SYT11/ETS1/PRKCE/MACF1/THBS1/SH2B3/TGFBR2/ITGB1/ENTPD1/DST/DGKH/PHLDB2/TIMP1/PDGFB/SLC12A2/GNAQ/IL6ST/TGFB1/GJA1/CFLAR/PLPP3/MYH9/PIK3CA/PTEN/CD59/FLNA/CD36/RAB27A/RHOA/DYSF/HIF1A/FERMT2/GATA2/VCL/PLSCR1/FZD6/CD44/CD9/PPP3CA/F11R/CD151/CRK/SMAD2/PLEC/MYL12A/PTK2/JMJD1C/MYOF	76
GO:0034329	cell junction assembly	75/988	420/18722	6.45546476461158e-21	3.42914288296167e-18	PECAM1/APLNR/CDH5/RAMP2/CLDN5/KDR/ACVRL1/ESAM/HEG1/TEK/ADGRL2/FSCN1/CLDN11/ITGA2/DCHS1/EFNB2/MEF2C/PLXND1/FN1/THSD1/CAV1/PKP4/AGRN/MACF1/DLC1/PEAK1/TJP1/THBS1/HDAC7/PPM1F/DST/MTDH/MPDZ/PHLDB2/NRP1/PDLIM5/APP/LIMCH1/LAMC1/PRKCH/CTNND1/JAM3/GJA1/LIMS1/PTEN/ITGA6/RHOA/FERMT2/MAP4K4/SDCBP/NPTN/PKN2/VCL/CTTN/MYO1C/RAPGEF2/HIPK1/CTNNA1/APC/IQGAP1/CD9/ARHGEF7/PAK2/F11R/GJA5/PTPRA/PLEC/MYO9A/PDCD6IP/ROCK2/STRN/ROCK1/CDC42/PTK2/RAP1A	75
GO:0010810	regulation of cell-substrate adhesion	52/988	221/18722	2.86068241553435e-20	1.35435580416791e-17	KDR/ACVRL1/TEK/NDNF/LIMS2/FOXF1/FZD4/FN1/JAG1/ADAM15/ANGPT2/NID1/PRKCE/MACF1/DLC1/PEAK1/THBS1/NEDD9/PPM1F/NOTCH1/PHLDB2/UTRN/NRP1/PDGFB/ACTN4/LGALS1/LIMCH1/CDK6/MDK/RIN2/LIMS1/ATXN3/PTEN/FLNA/RRAS/CD36/ITGA6/RHOA/HSD17B12/FERMT2/MAP4K4/VCL/EMP2/IQGAP1/ARHGEF7/PTPRA/CRK/ROCK2/ROCK1/CDC42/PTK2/DOCK1	52
GO:0045446	endothelial cell differentiation	38/988	118/18722	3.05953871423475e-20	1.35435580416791e-17	PECAM1/COL15A1/CDH5/CLDN5/KDR/ACVRL1/ZEB1/HEG1/TIE1/ROBO4/SOX18/S1PR1/HOXA13/COL18A1/NOTCH4/CEACAM1/BMPR2/JAG1/PDE4D/MSN/PLCB1/TJP1/ID1/NOTCH1/FSTL1/NRP1/VEZF1/RDX/NR2F2/VCL/CLIC4/RAPGEF2/ADD1/F11R/ROCK2/ROCK1/SMAD4/RAP1A	38
GO:1901342	regulation of vasculature development	64/988	348/18722	1.11588189558858e-18	4.5596650995127e-16	SPARC/APLNR/CDH5/CD34/RAMP2/CLDN5/KDR/ACVRL1/TIE1/TEK/VEGFC/RHOJ/CEACAM1/ADGRA2/NPR1/ENPP2/HSPG2/HHEX/PLXND1/ENG/ITGA5/COL4A2/ETS1/ANGPT2/TSPAN12/KLF2/TJP1/THBS1/ID1/VASH1/TGFBR2/ITGB1/RHOB/STAB1/RGCC/MTDH/SMAD1/NRP1/SASH1/HIPK2/MDK/JAK1/SLC12A2/ERAP1/PML/AKT3/KLF4/GTF2I/EGLN1/RRAS/HIF1A/PTPRM/STAT3/ADAM10/GATA2/ATP2B4/HIPK1/EMP2/SP100/ATF2/ROCK2/ROCK1/SYNJ2BP/PLK2	64
GO:0010594	regulation of endothelial cell migration	51/988	232/18722	1.55171779621643e-18	5.88766066678692e-16	SPARC/EDN1/KDR/MMRN2/ACVRL1/MEOX2/TEK/VEGFC/RHOJ/CEACAM1/ADGRA2/MEF2C/BMPR2/PRCP/FGFR1/SCARB1/FOXP1/ETS1/ANGPT2/THBS1/ANGPT1/HDAC7/NOTCH1/VASH1/RHOB/TMSB4X/RGCC/NRP1/PDGFB/SASH1/MAP3K3/TGFB1/RIN2/PLPP3/AKT3/KLF4/RRAS/RHOA/HIF1A/PTPRM/PIK3C2A/GATA2/NR2F2/STARD13/ATP2B4/EMP2/SP100/ROCK2/SYNJ2BP/PTK2/PLK2	51
GO:0045216	cell-cell junction organization	47/988	200/18722	2.03226247429769e-18	7.1969188423129e-16	PECAM1/APLNR/CDH5/RAMP2/CLDN5/ESAM/HEG1/FSCN1/LIMS2/CLDN11/DCHS1/F2R/CAV1/PKP4/TJP1/HDAC7/MTDH/MPDZ/PRKCH/CTNND1/JAM3/TGFB1/GJA1/LIMS1/FLNA/RDX/RHOA/FERMT2/ADAM10/PKN2/VCL/MYO1C/HIPK1/ADD1/CTNNA1/APC/CD9/PAK2/F11R/GJA5/PLEC/PDCD6IP/ROCK2/STRN/ROCK1/CDC42/MTSS1	47
GO:0045765	regulation of angiogenesis	62/988	342/18722	8.21360973844317e-18	2.72691843316313e-15	SPARC/APLNR/CDH5/CD34/RAMP2/CLDN5/KDR/ACVRL1/TIE1/TEK/VEGFC/RHOJ/CEACAM1/ADGRA2/NPR1/ENPP2/HSPG2/HHEX/PLXND1/ENG/ITGA5/COL4A2/ETS1/ANGPT2/TSPAN12/KLF2/TJP1/THBS1/VASH1/TGFBR2/ITGB1/RHOB/STAB1/RGCC/MTDH/SMAD1/NRP1/SASH1/HIPK2/MDK/JAK1/SLC12A2/ERAP1/PML/AKT3/KLF4/GTF2I/EGLN1/RRAS/HIF1A/PTPRM/STAT3/GATA2/ATP2B4/HIPK1/EMP2/SP100/ATF2/ROCK2/ROCK1/SYNJ2BP/PLK2	62
GO:0045785	positive regulation of cell adhesion	70/988	437/18722	5.82356111009614e-17	1.78056055902964e-14	KDR/IGF1/TEK/SELP/PODXL/NDNF/LIMS2/HLX/FOXF1/ITGA2/FN1/CAV1/MAGI1/ETS1/PIEZO1/NID1/HLA-E/PRKCE/HLA-A/TJP1/ANGPT1/NEDD9/PPM1F/TGFBR2/IGF2/B2M/CD81/UTRN/NRP1/PDGFB/LGALS1/CDK6/MDK/YES1/JAK1/EFNB1/IL6ST/RIN2/LIMS1/STX3/PLPP3/FYN/PIK3CA/TNFRSF14/NFAT5/FLNA/RRAS/MYO10/CD36/ITGA6/RHOA/HSD17B12/FERMT2/MAP4K4/ZMIZ1/EMP2/IQGAP1/CD44/ARHGEF7/PPP3CA/F11R/CRK/CD46/HES1/ROCK1/CDC42/DOCK1/KIFAP3/HSPH1/BCL10	70
GO:0007044	cell-substrate junction assembly	31/988	95/18722	6.0335259906878e-17	1.78056055902964e-14	KDR/ACVRL1/TEK/ITGA2/FN1/THSD1/MACF1/DLC1/PEAK1/THBS1/PPM1F/DST/PHLDB2/NRP1/LIMCH1/LAMC1/LIMS1/PTEN/ITGA6/RHOA/FERMT2/MAP4K4/VCL/CTTN/IQGAP1/ARHGEF7/PTPRA/PLEC/ROCK2/ROCK1/PTK2	31
GO:0071559	response to transforming growth factor beta	51/988	256/18722	1.26641662928799e-16	3.540634281462e-14	CDH5/CLDN5/EDN1/ACVRL1/COL3A1/LRRC32/CD109/CLEC3B/HYAL2/MEF2C/SMAD6/ENG/CAV1/CAV2/COL4A2/FKBP1A/THBS1/ID1/TGFBR2/SKIL/SMAD5/LTBP1/SMAD1/PXN/ZFP36L1/SMURF2/HIPK2/YES1/PML/TGFB1/LIMS1/CFLAR/FYN/SKI/FERMT2/SDCBP/CREB1/STAT3/HTRA1/ZMIZ1/ZFP36L2/CRK/LTBP3/SMAD2/NR3C1/ROCK2/ROCK1/PTK2/HSPA1A/SMAD4/JUN	51
GO:0150115	cell-substrate junction organization	31/988	101/18722	4.29823598502802e-16	1.09112533232383e-13	KDR/ACVRL1/TEK/ITGA2/FN1/THSD1/MACF1/DLC1/PEAK1/THBS1/PPM1F/DST/PHLDB2/NRP1/LIMCH1/LAMC1/LIMS1/PTEN/ITGA6/RHOA/FERMT2/MAP4K4/VCL/CTTN/IQGAP1/ARHGEF7/PTPRA/PLEC/ROCK2/ROCK1/PTK2	31
GO:0043534	blood vessel endothelial cell migration	41/988	176/18722	4.31356023697298e-16	1.09112533232383e-13	CDH5/KDR/MMRN2/ACVRL1/MEOX2/CLEC14A/SOX18/VEGFC/RHOJ/EFNB2/MEF2C/PRCP/FGFR1/SCARB1/ETS1/ANGPT2/THBS1/ANGPT1/HDAC7/ID1/NOTCH1/VASH1/ITGB1/TMSB4X/RGCC/PIK3R3/NRP1/PDGFB/MAP3K3/TGFB1/AKT3/MYH9/KLF4/RHOA/HIF1A/PIK3C2A/GATA2/STARD13/ATP2B4/EMP2/PLK2	41
GO:0071560	cellular response to transforming growth factor beta stimulus	49/988	250/18722	1.00132854705499e-15	2.41775329179822e-13	CDH5/CLDN5/EDN1/ACVRL1/COL3A1/LRRC32/CD109/CLEC3B/HYAL2/MEF2C/SMAD6/ENG/CAV1/CAV2/COL4A2/FKBP1A/THBS1/ID1/TGFBR2/SKIL/SMAD5/LTBP1/SMAD1/PXN/ZFP36L1/SMURF2/HIPK2/YES1/PML/TGFB1/LIMS1/CFLAR/FYN/SKI/FERMT2/SDCBP/CREB1/STAT3/HTRA1/ZMIZ1/ZFP36L2/CRK/LTBP3/SMAD2/NR3C1/PTK2/HSPA1A/SMAD4/JUN	49
GO:0001570	vasculogenesis	27/988	80/18722	2.36930224560563e-15	5.37983879116713e-13	EGFL7/APLNR/CD34/RAMP2/KDR/HEG1/TIE1/SOX18/HOXA13/RASIP1/CEACAM1/FOXF1/FZD4/ENG/CAV1/HDAC7/NOTCH1/TGFBR2/ZFP36L1/TGFB1/RIN2/RRAS/QKI/ZMIZ1/RAPGEF2/EMP2/RAP1A	27
GO:0010634	positive regulation of epithelial cell migration	40/988	176/18722	2.43065005625021e-15	5.37983879116713e-13	SPARC/EDN1/KDR/TEK/VEGFC/RHOJ/ADGRA2/ITGA2/ENPP2/BMPR2/FGFR1/SCARB1/FOXP1/ETS1/PRKCE/THBS1/ANGPT1/HDAC7/PPM1F/TGFBR2/RHOB/TMSB4X/NRP1/PDGFB/SASH1/MAP3K3/TGFB1/RIN2/PLPP3/AKT3/RRAS/HIF1A/PIK3C2A/MAP4K4/GATA2/RTN4/RAB11A/ROCK2/DOCK1/PLK2	40
GO:0001885	endothelial cell development	24/988	64/18722	5.49195133776549e-15	1.16692982024841e-12	PECAM1/COL15A1/CDH5/CLDN5/HEG1/ROBO4/SOX18/HOXA13/COL18A1/NOTCH4/PDE4D/MSN/PLCB1/TJP1/VEZF1/RDX/VCL/CLIC4/RAPGEF2/ADD1/F11R/ROCK2/ROCK1/RAP1A	24
GO:0032970	regulation of actin filament-based process	62/988	396/18722	1.10651457573112e-14	2.2606943947245e-12	SPTBN1/BST2/EDN1/ESAM/TEK/CGNL1/S1PR1/KANK3/FSCN1/ARHGEF15/CDC42EP5/CAV1/PDE4D/PAM/PRKCE/DLC1/SPTAN1/DIXDC1/TJP1/PPM1F/ID1/RHOB/TMSB4X/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/NCKAP1/MDK/JAM3/TAOK1/TMSB10/MYH9/PIK3CA/TMOD3/PDE4B/FLNA/RDX/ACTR2/RHOA/ABI2/FERMT2/CTTN/MYO1C/ADD1/CCDC88A/IQGAP1/PAK2/F11R/GJA5/CRK/GSN/ROCK2/WASL/ROCK1/CDC42/ARHGAP17/SMAD4/DSTN/MTSS1	62
GO:0007265	Ras protein signal transduction	56/988	337/18722	1.67687552475927e-14	3.29909732871157e-12	ARHGAP29/IGF1/HEG1/COL3A1/RHOJ/RASIP1/F2R/CDC42EP5/LPAR6/RASA4/DLC1/ARHGEF12/NOTCH1/ITGB1/RHOB/ELMO1/HACE1/NRP1/RB1/NCKAP1/GNB1/RGL2/GDI1/RRAS/RDX/RHOA/ABI2/OGT/MAP4K4/ARPP19/CYTH1/SDCBP/PHACTR4/RALB/ABCA1/TNFAIP1/STARD13/RAPGEF2/ARHGAP5/PPP2CB/F11R/G3BP1/SHOC2/CRK/ARHGEF3/RALA/ARFGEF3/ROCK2/ROCK1/NRAS/CDC42/SOS1/ARHGAP17/PLK2/JUN/RAP1A	56
GO:0007043	cell-cell junction assembly	35/988	146/18722	2.45742939340563e-14	4.66209462063239e-12	PECAM1/APLNR/CDH5/RAMP2/CLDN5/ESAM/HEG1/FSCN1/CLDN11/DCHS1/CAV1/PKP4/TJP1/HDAC7/MTDH/MPDZ/PRKCH/CTNND1/JAM3/GJA1/RHOA/PKN2/VCL/MYO1C/HIPK1/CTNNA1/APC/CD9/PAK2/F11R/GJA5/PDCD6IP/ROCK2/STRN/ROCK1	35
GO:0032956	regulation of actin cytoskeleton organization	57/988	357/18722	5.7214308954281e-14	1.048008307466e-11	SPTBN1/BST2/EDN1/ESAM/TEK/CGNL1/S1PR1/KANK3/FSCN1/ARHGEF15/CDC42EP5/PAM/PRKCE/DLC1/SPTAN1/DIXDC1/TJP1/PPM1F/ID1/RHOB/TMSB4X/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/NCKAP1/MDK/JAM3/TAOK1/TMSB10/PIK3CA/TMOD3/FLNA/RDX/ACTR2/RHOA/ABI2/FERMT2/CTTN/MYO1C/ADD1/CCDC88A/IQGAP1/PAK2/F11R/CRK/GSN/ROCK2/WASL/ROCK1/CDC42/ARHGAP17/SMAD4/DSTN/MTSS1	57
GO:0002064	epithelial cell development	43/988	220/18722	6.44949671522518e-14	1.14199088504254e-11	PECAM1/COL15A1/CDH5/VIM/CLDN5/HEG1/ROBO4/SOX18/PODXL/HOXA13/COL18A1/NOTCH4/JAG1/PDE4D/MSN/PLCB1/TJP1/LAMB2/NOTCH1/FLNB/PDGFB/CDK6/IL6ST/ATRX/VEZF1/PALLD/FLNA/RDX/FNDC3A/ABI2/HIF1A/VCL/CLIC4/RAPGEF2/FEM1B/ADD1/IQGAP1/CLOCK/F11R/PLEC/ROCK2/ROCK1/RAP1A	43
GO:0016032	viral process	62/988	415/18722	9.84891057070735e-14	1.68765848230959e-11	IFI27/BST2/NFIA/BICD1/ITGA2/HYAL2/EFNB2/ITGA5/CAV1/IFITM2/PCSK5/CAV2/SCARB1/IFITM3/NOTCH1/IFI16/ITGB1/IFITM1/ST6GAL1/CD81/CANX/NRP1/STOM/MDFIC/LGALS1/SCARB2/SPCS3/PABPC1/PML/OAS2/KPNA3/LAMP1/TNFRSF14/MX1/MGAT4A/ISG15/ZFP36/EIF2AK2/CSDE1/ADAR/PKN2/PCBP2/PARP9/ZC3HAV1/FAM111A/PLSCR1/RSF1/F11R/TRIM13/CTBP2/XPR1/GSN/CD46/PDCD6IP/ROCK2/DDX6/CDC42/HSPA1A/NEDD4/JUN/RAB5A/CCNT1	62
GO:0007160	cell-matrix adhesion	44/988	233/18722	1.17847375727699e-13	1.9562664370798e-11	CD34/KDR/ACVRL1/TEK/COL3A1/ITGA2/FN1/THSD1/JAG1/ITGA1/ADAM15/NID1/MACF1/DLC1/PEAK1/THBS1/PPM1F/ITGB1/PHLDB2/UTRN/PXN/NRP1/LIMCH1/CDK6/JAM3/RIN2/LIMS1/PTEN/RRAS/CD36/RHOA/FERMT2/MAP4K4/MKLN1/VCL/CTTN/EMP2/IQGAP1/CD44/ARHGEF7/PTPRA/ROCK2/ROCK1/PTK2	44
GO:0007015	actin filament organization	64/988	441/18722	1.52419340104016e-13	2.45348949888646e-11	SPTBN1/ESAM/CGNL1/S1PR1/PLS3/KANK3/FSCN1/SHROOM4/ARHGEF15/SORBS2/CDC42EP5/MARCKSL1/HIP1/MARCKS/PRKCE/DLC1/SPTAN1/TJP1/NEDD9/PPM1F/ID1/SHROOM1/RHOB/TMSB4X/RGCC/ELMO1/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/NCKAP1/TMSB10/PIK3CA/TMOD3/TPM3/FLNA/RDX/ACTR2/RHOA/ABI2/CALD1/FERMT2/HSP90B1/TNFAIP1/CTTN/MYO1C/ADD1/EMP2/CTNNA1/CCDC88A/RUFY3/TPM4/PAK2/F11R/PLEC/GSN/ROCK2/WASL/ROCK1/CDC42/TTC17/DSTN/MTSS1	64
GO:0010811	positive regulation of cell-substrate adhesion	31/988	123/18722	1.74278214934934e-13	2.72284081686579e-11	KDR/TEK/NDNF/LIMS2/FOXF1/FN1/NID1/PRKCE/NEDD9/PPM1F/UTRN/NRP1/PDGFB/CDK6/MDK/RIN2/LIMS1/FLNA/RRAS/CD36/ITGA6/HSD17B12/FERMT2/MAP4K4/EMP2/IQGAP1/ARHGEF7/CRK/ROCK1/CDC42/DOCK1	31
GO:0048041	focal adhesion assembly	26/988	87/18722	2.05794038266792e-13	3.12336551792343e-11	KDR/ACVRL1/TEK/ITGA2/THSD1/MACF1/DLC1/PEAK1/THBS1/PPM1F/PHLDB2/NRP1/LIMCH1/LIMS1/PTEN/RHOA/FERMT2/MAP4K4/VCL/CTTN/IQGAP1/ARHGEF7/PTPRA/ROCK2/ROCK1/PTK2	26
GO:0002040	sprouting angiogenesis	38/988	185/18722	3.69002877211045e-13	5.44484245484742e-11	APLNR/RAMP2/KDR/MMRN2/ACVRL1/RSPO3/MEOX2/CLEC14A/TEK/VEGFC/RHOJ/LOXL2/CEACAM1/ADGRA2/EFNB2/ITGA5/KLF2/TJP1/THBS1/ANGPT1/HDAC7/NOTCH1/ITGB1/SMAD1/PIK3R3/NRP1/JAK1/MAP3K3/AKT3/KLF4/RHOA/PIK3C2A/GATA2/STARD13/CDC42/SYNJ2BP/RNF213/PLK2	38
GO:0007229	integrin-mediated signaling pathway	28/988	107/18722	9.49889673092815e-13	1.36373349823487e-10	COL3A1/LIMS2/CEACAM1/ITGA2/FN1/ITGA5/ITGA1/ADAM15/NEDD9/ITGB1/DST/NRP1/TIMP1/LIMS1/PLPP3/MYH9/FLNA/ISG15/ITGA6/FERMT2/PHACTR4/ADAM10/EMP2/CTNNA1/PTPRA/CDC42/PTK2/DOCK1	28
GO:1902903	regulation of supramolecular fiber organization	57/988	382/18722	1.05566446344945e-12	1.47570779732723e-10	CDH5/SPTBN1/EDN1/ESAM/CGNL1/S1PR1/KANK3/ARHGEF15/CDC42EP5/PRKCE/DLC1/SPTAN1/TJP1/PPM1F/ID1/TMSB4X/RGCC/ARHGAP28/CLU/PHLDB2/PXN/NRP1/GIT1/APP/LIMCH1/RB1/NCKAP1/TAOK1/TMSB10/PIK3CA/TMOD3/FLNA/RDX/ACTR2/RHOA/ABI2/FERMT2/CTTN/MYO1C/ADD1/APC/CCDC88A/ARHGEF7/PAK2/F11R/GSN/ROCK2/WASL/DYRK1A/ROCK1/CDC42/HSPA1A/SMAD4/DSTN/CAMSAP2/MTSS1/NIN	57
GO:0051893	regulation of focal adhesion assembly	22/988	66/18722	1.22827679636197e-12	1.63115158556869e-10	KDR/ACVRL1/TEK/MACF1/DLC1/PEAK1/THBS1/PPM1F/PHLDB2/NRP1/LIMCH1/LIMS1/PTEN/RHOA/FERMT2/MAP4K4/VCL/IQGAP1/PTPRA/ROCK2/ROCK1/PTK2	22
GO:0090109	regulation of cell-substrate junction assembly	22/988	66/18722	1.22827679636197e-12	1.63115158556869e-10	KDR/ACVRL1/TEK/MACF1/DLC1/PEAK1/THBS1/PPM1F/PHLDB2/NRP1/LIMCH1/LIMS1/PTEN/RHOA/FERMT2/MAP4K4/VCL/IQGAP1/PTPRA/ROCK2/ROCK1/PTK2	22
GO:0010595	positive regulation of endothelial cell migration	31/988	133/18722	1.66060992054708e-12	2.1515024141332e-10	SPARC/EDN1/KDR/TEK/VEGFC/RHOJ/ADGRA2/BMPR2/FGFR1/SCARB1/FOXP1/ETS1/THBS1/ANGPT1/HDAC7/RHOB/TMSB4X/NRP1/PDGFB/SASH1/MAP3K3/TGFB1/RIN2/PLPP3/AKT3/RRAS/HIF1A/PIK3C2A/GATA2/ROCK2/PLK2	31
GO:0050673	epithelial cell proliferation	61/988	437/18722	3.18912026869797e-12	3.98704553270629e-10	SPARC/EGFL7/APLNR/CD34/IGFBP4/KDR/NFIB/IGF1/ACVRL1/TIE1/TEK/CD109/VEGFC/LIMS2/LOXL2/CEACAM1/MEF2C/CAV1/BMPR2/FGFR1/CAV2/SCARB1/THBS1/ID1/NOTCH1/VASH1/IGF2/RGCC/B2M/ZFP36L1/NRP1/PDGFB/SULF2/RB1/CDK6/MDK/LAMC1/TGFB1/GJA1/CFLAR/AKT3/PTEN/HIF1A/PTPRM/ZFP36/PURA/STAT3/GATA2/NR2F2/HTRA1/RTN4/CCND1/ATF2/HES1/NRAS/CDC42/SYNJ2BP/MAPK1/ID2/SAV1/MTSS1	61
GO:0001952	regulation of cell-matrix adhesion	30/988	128/18722	3.25901045359678e-12	3.98704553270629e-10	KDR/ACVRL1/TEK/JAG1/ADAM15/MACF1/DLC1/PEAK1/THBS1/PPM1F/PHLDB2/UTRN/NRP1/LIMCH1/CDK6/RIN2/LIMS1/PTEN/RRAS/CD36/RHOA/FERMT2/MAP4K4/VCL/EMP2/IQGAP1/PTPRA/ROCK2/ROCK1/PTK2	30
GO:0019058	viral life cycle	50/988	317/18722	3.3025226551031e-12	3.98704553270629e-10	IFI27/BST2/NFIA/ITGA2/HYAL2/EFNB2/ITGA5/CAV1/IFITM2/PCSK5/CAV2/SCARB1/IFITM3/NOTCH1/IFI16/ITGB1/IFITM1/CD81/NRP1/STOM/LGALS1/SCARB2/PABPC1/PML/OAS2/KPNA3/LAMP1/TNFRSF14/MX1/ISG15/EIF2AK2/ADAR/PKN2/PCBP2/ZC3HAV1/FAM111A/PLSCR1/F11R/TRIM13/CTBP2/XPR1/GSN/CD46/PDCD6IP/ROCK2/DDX6/CDC42/HSPA1A/NEDD4/RAB5A	50
GO:0150116	regulation of cell-substrate junction organization	22/988	71/18722	6.5138922427019e-12	7.68928790960722e-10	KDR/ACVRL1/TEK/MACF1/DLC1/PEAK1/THBS1/PPM1F/PHLDB2/NRP1/LIMCH1/LIMS1/PTEN/RHOA/FERMT2/MAP4K4/VCL/IQGAP1/PTPRA/ROCK2/ROCK1/PTK2	22
GO:0051017	actin filament bundle assembly	33/988	157/18722	6.76364495649187e-12	7.81053956714887e-10	CGNL1/S1PR1/PLS3/FSCN1/ARHGEF15/MARCKS/DLC1/TJP1/NEDD9/PPM1F/ID1/SHROOM1/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/FLNA/RDX/RHOA/CALD1/FERMT2/HSP90B1/TNFAIP1/ADD1/CCDC88A/PAK2/F11R/ROCK2/ROCK1/CDC42/MTSS1	33
GO:0050878	regulation of body fluid levels	55/988	379/18722	8.18893180610992e-12	9.2552352668204e-10	VWF/MMRN1/APLNR/CD34/EDN1/HEG1/SELP/COL3A1/FLI1/P2RY1/PROS1/CEACAM1/ITGA2/F2R/NPR1/HYAL2/FN1/CAV1/TFPI2/THBD/TFPI/PAM/PRKCE/THBS1/UGCG/SH2B3/ENTPD1/DGKH/PDGFB/GNAI2/AKAP11/GNAQ/IL6ST/GJA1/OAS2/MYH9/PIK3CA/CD59/FLNA/CD36/RAB27A/HIF1A/CREB1/VCL/PLSCR1/FZD6/EMP2/CD9/CCND1/F11R/GJA5/PLEC/MYL12A/WNK1/JMJD1C	55
GO:0061572	actin filament bundle organization	33/988	161/18722	1.39494853100518e-11	1.54374304097906e-09	CGNL1/S1PR1/PLS3/FSCN1/ARHGEF15/MARCKS/DLC1/TJP1/NEDD9/PPM1F/ID1/SHROOM1/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/FLNA/RDX/RHOA/CALD1/FERMT2/HSP90B1/TNFAIP1/ADD1/CCDC88A/PAK2/F11R/ROCK2/ROCK1/CDC42/MTSS1	33
GO:0001701	in utero embryonic development	53/988	367/18722	2.38463609146034e-11	2.58514018731374e-09	HSD17B2/EDN1/IGF1/ACVRL1/RSPO3/HEG1/TIE1/SOX18/FOXF1/PCDH12/NXN/LPAR6/EPAS1/KLF2/ANGPT1/NOTCH1/VASH1/TGFBR2/IGF2/ITGB1/SKIL/MFNG/ATP11A/PCGF2/ZFP36L1/BCOR/PDGFB/SOCS3/MBNL1/MYH9/N4BP2L2/KLF4/MIB1/GABPA/CAPN2/HIF1A/CMTM3/ADAM10/GATA2/SLC30A1/NR2F2/PKD2/ZMIZ1/RTN4/TBX3/HECTD1/SMAD2/ATF2/HES1/BPTF/CNOT2/MAPK1/SMAD4	53
GO:0050678	regulation of epithelial cell proliferation	54/988	381/18722	3.20039664689834e-11	3.40010139766479e-09	SPARC/EGFL7/APLNR/KDR/NFIB/IGF1/ACVRL1/TIE1/TEK/CD109/VEGFC/LIMS2/CEACAM1/MEF2C/CAV1/BMPR2/FGFR1/CAV2/THBS1/ID1/NOTCH1/VASH1/IGF2/RGCC/B2M/ZFP36L1/NRP1/PDGFB/SULF2/RB1/CDK6/MDK/LAMC1/TGFB1/GJA1/CFLAR/AKT3/PTEN/HIF1A/PTPRM/ZFP36/STAT3/GATA2/NR2F2/HTRA1/RTN4/CCND1/ATF2/HES1/NRAS/CDC42/SYNJ2BP/SAV1/MTSS1	54
GO:1901888	regulation of cell junction assembly	37/988	204/18722	3.67577693143434e-11	3.82857393329004e-09	APLNR/CLDN5/KDR/ACVRL1/TEK/ADGRL2/MEF2C/CAV1/AGRN/MACF1/DLC1/PEAK1/TJP1/THBS1/PPM1F/PHLDB2/NRP1/PDLIM5/APP/LIMCH1/PRKCH/GJA1/LIMS1/PTEN/RHOA/FERMT2/MAP4K4/VCL/MYO1C/RAPGEF2/IQGAP1/F11R/PTPRA/ROCK2/ROCK1/PTK2/RAP1A	37
GO:0045936	negative regulation of phosphate metabolic process	59/988	441/18722	4.23895041210193e-11	4.33025088251643e-09	PTPRB/FABP4/LRP6/HEG1/CD109/RASIP1/CEACAM1/HYAL2/WWTR1/HHEX/SMAD6/ENG/CAV1/PDE4D/SH3BP5/FKBP1A/ANGPT1/PPP2R5A/PPM1F/SH2B3/PKIG/PDGFB/GIT1/RB1/DNAJC10/GNAI2/PKN1/SOCS3/GNAQ/CALM1/DUSP1/AIDA/TGFB1/DUSP6/PRKAR1A/PLPP3/IGFBP3/TRIB2/PARP14/PTEN/ARPP19/STAT3/HIPK3/ADAR/NR2F2/CTDSP2/APC/SPAG9/SOCS4/PAK2/CTDSP1/CBLB/PLEC/WNK1/MIDN/PRKAR2A/ROCK2/ROCK1/YWHAB	59
GO:0010563	negative regulation of phosphorus metabolic process	59/988	442/18722	4.64960243706561e-11	4.66012983880991e-09	PTPRB/FABP4/LRP6/HEG1/CD109/RASIP1/CEACAM1/HYAL2/WWTR1/HHEX/SMAD6/ENG/CAV1/PDE4D/SH3BP5/FKBP1A/ANGPT1/PPP2R5A/PPM1F/SH2B3/PKIG/PDGFB/GIT1/RB1/DNAJC10/GNAI2/PKN1/SOCS3/GNAQ/CALM1/DUSP1/AIDA/TGFB1/DUSP6/PRKAR1A/PLPP3/IGFBP3/TRIB2/PARP14/PTEN/ARPP19/STAT3/HIPK3/ADAR/NR2F2/CTDSP2/APC/SPAG9/SOCS4/PAK2/CTDSP1/CBLB/PLEC/WNK1/MIDN/PRKAR2A/ROCK2/ROCK1/YWHAB	59
GO:0051098	regulation of binding	52/988	363/18722	5.00456438535486e-11	4.92300852129723e-09	RAMP2/CLDN5/IGF1/P2RY1/ITGA2/PLXND1/CAV1/CLIC2/FKBP1A/ADAM15/ANGPT1/ID1/IFI16/TMSB4X/MFNG/ARHGAP28/B2M/NRP1/PDGFB/CARD16/HIPK2/APP/RB1/CALM1/TGFB1/HMBOX1/KLF4/SKI/TMBIM6/RALB/PARP9/IFIT2/RAPGEF2/ADD1/CSNK1A1/PPP2CB/RSF1/ARHGEF7/PPP3CA/SP100/CBLB/CTBP2/CRK/SMAD2/DTX3L/HES1/ROCK1/CDC42/PLK2/SMAD4/JUN/ZMPSTE24	52
GO:0043297	apical junction assembly	22/988	78/18722	5.21021595970095e-11	5.03212130507845e-09	PECAM1/CDH5/RAMP2/CLDN5/ESAM/CLDN11/TJP1/MTDH/PRKCH/GJA1/RHOA/PKN2/VCL/MYO1C/CTNNA1/APC/PAK2/F11R/PDCD6IP/ROCK2/STRN/ROCK1	22
GO:0022604	regulation of cell morphogenesis	47/988	309/18722	5.40342413182599e-11	5.12553374790351e-09	SPARC/KDR/PALMD/P2RY1/FGD5/LIMS2/RHOJ/FZD4/ENPP2/CDC42EP5/PLXND1/FN1/MSN/PARVB/MACF1/DLC1/NEDD9/FGD4/RHOB/NRP1/ACTN4/MDK/ITSN2/LIMS1/FYN/PLXNA2/MYH9/FLNA/RDX/MYO10/ACTR2/RHOA/FERMT2/MKLN1/MYL12B/SPAG9/CD44/ARHGEF7/F11R/CRK/PHIP/MYL12A/MYO9A/CDC42/PTK2/DOCK1/ZMPSTE24	47
GO:0043535	regulation of blood vessel endothelial cell migration	31/988	151/18722	5.54660910128397e-11	5.16905044667025e-09	KDR/MMRN2/ACVRL1/MEOX2/VEGFC/RHOJ/MEF2C/PRCP/FGFR1/ETS1/ANGPT2/THBS1/ANGPT1/HDAC7/NOTCH1/VASH1/TMSB4X/RGCC/NRP1/PDGFB/MAP3K3/TGFB1/AKT3/KLF4/RHOA/HIF1A/PIK3C2A/GATA2/STARD13/ATP2B4/PLK2	31
GO:0007179	transforming growth factor beta receptor signaling pathway	36/988	198/18722	6.28740654593698e-11	5.75839716758918e-09	CDH5/CLDN5/ACVRL1/COL3A1/LRRC32/CD109/SMAD6/ENG/CAV1/CAV2/FKBP1A/THBS1/ID1/TGFBR2/SKIL/SMAD5/LTBP1/SMAD1/PXN/SMURF2/HIPK2/PML/TGFB1/SKI/FERMT2/SDCBP/CREB1/STAT3/HTRA1/ZMIZ1/LTBP3/SMAD2/PTK2/HSPA1A/SMAD4/JUN	36
GO:0061028	establishment of endothelial barrier	17/988	46/18722	6.83621889552531e-11	6.15491436831024e-09	PECAM1/CDH5/CLDN5/ROBO4/SOX18/PDE4D/MSN/PLCB1/TJP1/RDX/VCL/RAPGEF2/ADD1/F11R/ROCK2/ROCK1/RAP1A	17
GO:0035633	maintenance of blood-brain barrier	15/988	35/18722	7.41627634107846e-11	6.56587665396813e-09	PECAM1/CDH5/CLDN5/JAM2/ESAM/LAMA2/TJP1/ANGPT1/ITGB1/SLC12A2/LAMC1/JAM3/GJA1/VCL/F11R	15
GO:0001666	response to hypoxia	46/988	307/18722	1.45102587901139e-10	1.25609105286773e-08	CD34/RAMP2/EDN1/ACVRL1/TEK/HIF3A/NDNF/VEGFC/LOXL2/ITGA2/CAV1/ITPR1/EPAS1/ADAM15/ETS1/ANGPT2/PAM/PRKCE/THBS1/NOTCH1/TGFBR2/RGCC/ZFP36L1/CARD16/HIPK2/PML/GNB1/CFLAR/MALAT1/PLOD2/PTEN/CAPN2/ERO1A/ITPR2/EGLN1/RHOA/HIF1A/NDRG1/HSP90B1/TMBIM6/CREB1/EGR1/SLC2A1/PRKAA1/ROCK2/SMAD4	46
GO:0042326	negative regulation of phosphorylation	53/988	385/18722	1.46607012947664e-10	1.25609105286773e-08	PTPRB/FABP4/LRP6/HEG1/CD109/RASIP1/CEACAM1/HYAL2/WWTR1/HHEX/SMAD6/ENG/CAV1/PDE4D/SH3BP5/ANGPT1/PPP2R5A/PPM1F/SH2B3/PKIG/GIT1/RB1/DNAJC10/PKN1/SOCS3/GNAQ/CALM1/DUSP1/AIDA/TGFB1/DUSP6/PRKAR1A/PLPP3/IGFBP3/TRIB2/PARP14/PTEN/STAT3/HIPK3/ADAR/NR2F2/CTDSP2/APC/SPAG9/SOCS4/PAK2/CTDSP1/CBLB/PLEC/WNK1/MIDN/PRKAR2A/ROCK1	53
GO:0032102	negative regulation of response to external stimulus	56/988	420/18722	1.52711131055759e-10	1.28762147328285e-08	A2M/CDH5/CD34/FCGR2B/EDN1/CALCRL/IGF1/TEK/NT5E/CD109/PROS1/CEACAM1/FOXF1/THBD/TFPI/SYT11/ANGPT2/HLA-E/HLA-A/THBS1/HLA-B/NOTCH1/SEC14L1/SH2B3/IFI16/PHLDB2/NRP1/PDGFB/GIT1/CARD16/TSPAN6/RB1/MDK/YES1/SLC12A2/SOCS3/DUSP1/GJA1/CD200/FYN/CARD8/KLF4/PARP14/PTEN/ISG15/ZFP36/ADAR/SEMA3F/HTRA1/PCBP2/ASH1L/CD9/TNFRSF1B/NR1D2/CRK/PLK2	56
GO:0110053	regulation of actin filament organization	43/988	277/18722	1.85318471722082e-10	1.53814331529328e-08	SPTBN1/ESAM/CGNL1/S1PR1/KANK3/ARHGEF15/CDC42EP5/PRKCE/DLC1/SPTAN1/TJP1/PPM1F/ID1/TMSB4X/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/NCKAP1/TMSB10/PIK3CA/TMOD3/FLNA/RDX/ACTR2/RHOA/ABI2/FERMT2/CTTN/MYO1C/ADD1/CCDC88A/PAK2/F11R/GSN/ROCK2/WASL/ROCK1/CDC42/DSTN/MTSS1	43
GO:0003007	heart morphogenesis	40/988	246/18722	1.9309136441676e-10	1.56101050702089e-08	APLNR/CLDN5/CPE/ACVRL1/HEG1/TEK/SOX18/S1PR1/FOXF1/DCHS1/MEF2C/PLXND1/SMAD6/ENG/BMPR2/JAG1/ADGRG6/FKBP1A/ADAM15/DLC1/NOTCH1/TGFBR2/NRP1/TGFB1/MIB1/FLNA/HIF1A/PKD2/ZMIZ1/RTN4/TBX3/GJA5/NIPBL/ATF2/HES1/PTK2/SOS1/SMAD4/SAV1/ZMPSTE24	40
GO:0031032	actomyosin structure organization	35/988	196/18722	1.93950853658469e-10	1.56101050702089e-08	EDN1/CGNL1/S1PR1/ARHGEF15/EPB41L4A/CDC42BPA/DLC1/TJP1/PPM1F/ITGB1/RGCC/ARHGAP28/PHLDB2/PXN/MEF2A/NRP1/LIMCH1/CFLAR/PRKAR1A/MYH9/TMOD3/CNN3/RHOA/FERMT2/TNFAIP1/CCDC88A/PAK2/F11R/PLEC/PDCD6IP/CDC42BPB/ROCK2/ROCK1/CDC42/SMAD4	35
GO:0032835	glomerulus development	19/988	62/18722	2.21263478020776e-10	1.75425611230801e-08	PECAM1/CD34/TEK/PODXL/WWTR1/MEF2C/JAG1/ANGPT2/NID1/ANGPT1/LAMB2/NOTCH1/PDGFB/SULF2/CFLAR/EGR1/IQGAP1/HES1/MTSS1	19
GO:0036293	response to decreased oxygen levels	47/988	322/18722	2.26290067684408e-10	1.76772476402879e-08	CD34/RAMP2/EDN1/ACVRL1/TEK/HIF3A/NDNF/VEGFC/LOXL2/ITGA2/CAV1/ITPR1/EPAS1/ADAM15/ETS1/ANGPT2/PAM/PRKCE/THBS1/NOTCH1/TGFBR2/RGCC/ZFP36L1/CARD16/HIPK2/PML/GNB1/CFLAR/MALAT1/PLOD2/PTEN/CAPN2/ERO1A/ITPR2/EGLN1/RHOA/HIF1A/NDRG1/HSP90B1/TMBIM6/CREB1/EGR1/SLC2A1/PRKAA1/ROCK2/BNIP2/SMAD4	47
GO:0060485	mesenchyme development	44/988	291/18722	2.7150432184234e-10	2.09018979366161e-08	APLNR/EDN1/ACVRL1/LRP6/NOTCH4/TCF15/LOXL2/FOXF1/DCHS1/WWTR1/MEF2C/FN1/ENG/BMPR2/JAG1/FGFR1/ADAM15/NOTCH1/TGFBR2/RGCC/PHLDB2/ZFP36L1/NRP1/DDX17/MDK/EFNB1/TGFB1/PTEN/FLNA/HIF1A/FERMT2/SDCBP/PHACTR4/SEMA3F/PKD2/RTN4/TBX3/PPP3R1/SMAD2/HES1/ROCK2/ROCK1/MAPK1/SMAD4	44
GO:0070482	response to oxygen levels	49/988	347/18722	3.01507749491261e-10	2.28801309328225e-08	CD34/RAMP2/EDN1/ACVRL1/TEK/HIF3A/NDNF/VEGFC/LOXL2/ITGA2/CAV1/FOXO1/ITPR1/EPAS1/ADAM15/ETS1/ANGPT2/PAM/PRKCE/THBS1/NOTCH1/TGFBR2/RGCC/ZFP36L1/CARD16/HIPK2/PML/GNB1/CFLAR/MALAT1/PLOD2/PTEN/CAPN2/ERO1A/ITPR2/EGLN1/RHOA/HIF1A/NDRG1/HSP90B1/TMBIM6/CREB1/ATP6V1A/EGR1/SLC2A1/PRKAA1/ROCK2/BNIP2/SMAD4	49
GO:0045766	positive regulation of angiogenesis	33/988	181/18722	3.64690408842325e-10	2.6906047941256e-08	APLNR/CDH5/CD34/RAMP2/KDR/ACVRL1/TIE1/TEK/VEGFC/ENG/ITGA5/ETS1/ANGPT2/TJP1/THBS1/TGFBR2/ITGB1/RHOB/MTDH/SMAD1/NRP1/SASH1/HIPK2/MDK/JAK1/ERAP1/AKT3/KLF4/RRAS/HIF1A/STAT3/GATA2/HIPK1	33
GO:1904018	positive regulation of vasculature development	33/988	181/18722	3.64690408842325e-10	2.6906047941256e-08	APLNR/CDH5/CD34/RAMP2/KDR/ACVRL1/TIE1/TEK/VEGFC/ENG/ITGA5/ETS1/ANGPT2/TJP1/THBS1/TGFBR2/ITGB1/RHOB/MTDH/SMAD1/NRP1/SASH1/HIPK2/MDK/JAK1/ERAP1/AKT3/KLF4/RRAS/HIF1A/STAT3/GATA2/HIPK1	33
GO:0009896	positive regulation of catabolic process	61/988	492/18722	4.50769658931557e-10	3.25474149659232e-08	KDR/IGF1/ZBTB20/CAV1/FOXO1/MSN/PRKCE/SPTLC2/HACE1/CLU/MTDH/RNF144B/CD81/ZFP36L1/SMURF2/APP/PABPC1/CPT1A/GJA1/TP53INP1/TRIB2/ATXN3/PTEN/RNF19A/RDX/HIF1A/PIK3C2A/ZFP36/RALB/TNRC6B/CELF1/CNOT6L/ZC3HAV1/RC3H1/CSNK1A1/APC/HECTD1/TNFRSF1B/SOCS4/ZFP36L2/TRIM13/CBLB/PRKAA1/CNOT8/ATF6/WAC/DTX3L/SH3GLB1/ROCK2/TNRC6A/ROCK1/CNOT2/PTK2/HSPA1A/PIAS1/BTG2/NEDD4/PLK2/OAZ2/TMTC3/PAFAH1B2	61
GO:0007599	hemostasis	37/988	222/18722	4.53409018727092e-10	3.25474149659232e-08	VWF/MMRN1/CD34/EDN1/SELP/COL3A1/FLI1/P2RY1/PROS1/CEACAM1/ITGA2/F2R/FN1/CAV1/TFPI2/THBD/TFPI/THBS1/SH2B3/ENTPD1/DGKH/PDGFB/GNAQ/IL6ST/MYH9/PIK3CA/CD59/FLNA/CD36/RAB27A/VCL/PLSCR1/FZD6/CD9/F11R/MYL12A/JMJD1C	37
GO:0051271	negative regulation of cellular component movement	50/988	367/18722	7.04814531867959e-10	4.99196639104346e-08	CLDN5/BST2/MMRN2/ACVRL1/MEOX2/TIE1/COL3A1/DACH1/HYAL2/MEF2C/ENG/JAG1/ADAM15/ANGPT2/PLCB1/DLC1/THBS1/NOTCH1/VASH1/IFITM1/RHOB/RGCC/PHLDB2/TIMP1/LIMCH1/DUSP1/TGFB1/GJA1/CD200/TP53INP1/IGFBP3/KLF4/PTEN/RRAS/RHOA/PTPRM/STAT3/LRCH1/PTPRG/NR2F2/VCL/CLIC4/STARD13/ATP2B4/CTNNA1/CD9/SP100/CRK/WASL/SYNJ2BP	50
GO:0043254	regulation of protein-containing complex assembly	55/988	427/18722	8.1698560988999e-10	5.70241566283556e-08	CDH5/SPTBN1/ESAM/STXBP6/SELP/KANK3/FSCN1/RASIP1/CDC42EP5/SMAD6/MSN/THRA/PIEZO1/PRKCE/SPTAN1/TMSB4X/ARHGAP28/FNIP2/CLU/GIT1/RB1/NCKAP1/JAM3/AIDA/TGFB1/TMSB10/TMOD3/CARD8/SLF2/RDX/ISG15/ACTR2/CD36/RHOA/ABI2/FERMT2/CREB1/RALB/EIF2AK2/ABCA1/CTTN/MYO1C/ADD1/CRBN/ARHGEF7/ATF7IP/GSN/SH3GLB1/WASL/DYRK1A/CDC42/HSPA1A/CAMSAP2/SENP6/NIN	55
GO:0032231	regulation of actin filament bundle assembly	24/988	105/18722	8.26592631849281e-10	5.70241566283556e-08	CGNL1/S1PR1/ARHGEF15/DLC1/TJP1/PPM1F/ID1/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/FLNA/RDX/RHOA/FERMT2/CCDC88A/PAK2/F11R/ROCK2/ROCK1/CDC42/MTSS1	24
GO:0007596	blood coagulation	36/988	217/18722	8.87699935382429e-10	6.04546417532239e-08	VWF/MMRN1/CD34/EDN1/SELP/COL3A1/P2RY1/PROS1/CEACAM1/ITGA2/F2R/FN1/CAV1/TFPI2/THBD/TFPI/THBS1/SH2B3/ENTPD1/DGKH/PDGFB/GNAQ/IL6ST/MYH9/PIK3CA/CD59/FLNA/CD36/RAB27A/VCL/PLSCR1/FZD6/CD9/F11R/MYL12A/JMJD1C	36
GO:2000146	negative regulation of cell motility	49/988	359/18722	9.81289130576922e-10	6.59823779952482e-08	CLDN5/BST2/MMRN2/ACVRL1/MEOX2/TIE1/COL3A1/DACH1/HYAL2/MEF2C/ENG/JAG1/ADAM15/ANGPT2/PLCB1/DLC1/THBS1/NOTCH1/VASH1/IFITM1/RHOB/RGCC/PHLDB2/TIMP1/LIMCH1/DUSP1/TGFB1/GJA1/CD200/TP53INP1/IGFBP3/KLF4/PTEN/RRAS/RHOA/PTPRM/STAT3/LRCH1/PTPRG/NR2F2/VCL/CLIC4/STARD13/ATP2B4/CTNNA1/SP100/CRK/WASL/SYNJ2BP	49
GO:0045601	regulation of endothelial cell differentiation	16/988	47/18722	1.02713335490114e-09	6.82016547654358e-08	CDH5/CLDN5/ACVRL1/ZEB1/NOTCH4/CEACAM1/JAG1/PLCB1/ID1/NOTCH1/VEZF1/VCL/ADD1/F11R/ROCK2/ROCK1	16
GO:0090287	regulation of cellular response to growth factor stimulus	44/988	304/18722	1.11832895362753e-09	7.33402889094996e-08	CDH5/MMRN2/ACVRL1/HOXA13/CD109/VEGFC/FZD4/ADGRA2/HHEX/SMAD6/ENG/ITGA5/CAV1/BMPR2/FGFR1/CAV2/FKBP1A/TSPAN12/THBS1/NOTCH1/FSTL1/SKIL/LTBP1/SULF2/SMURF2/CRIM1/HIPK2/XIAP/TGFB1/CFLAR/HIF1A/SKI/SDCBP/NPTN/HTRA1/MYO1C/ATP2B4/ZDHHC17/SMAD2/HES1/HSPA1A/NEDD4/SMAD4/CTDSPL2	44
GO:0014706	striated muscle tissue development	51/988	384/18722	1.1711028149487e-09	7.58646116220429e-08	EDN1/IGF1/MEOX2/HEG1/S1PR1/HLX/SORBS2/EFNB2/MEF2C/ENG/CAV1/CAV2/FKBP1A/RCAN1/NOTCH1/TGFBR2/IGF2/ITGB1/SMAD5/SMAD1/FLNB/MEF2A/VAMP5/DDX17/PDLIM5/RB1/TGFB1/GJA1/CFLAR/PRKAR1A/PTEN/RHOA/SKI/CREB1/NR2F2/EGR1/TBX3/FOXN2/PPP3CA/PRKAA1/GJA5/NR1D2/PLEC/CDC42/MAPK1/ID2/MYL6/BTG2/SMAD4/SAV1/ZMPSTE24	51
GO:0003205	cardiac chamber development	30/988	161/18722	1.33599974746894e-09	8.55039838380123e-08	APLNR/CPE/HEG1/TEK/HOXA13/FOXF1/MEF2C/PLXND1/SMAD6/ENG/BMPR2/JAG1/ADGRG6/FKBP1A/NOTCH1/TGFBR2/NRP1/TGFB1/LUZP1/AP2B1/HIF1A/TBX3/HECTD1/GJA5/HES1/SOS1/SMAD4/ADAMTS6/SAV1/ZMPSTE24	30
GO:0050817	coagulation	36/988	222/18722	1.68221923249229e-09	1.06380340035703e-07	VWF/MMRN1/CD34/EDN1/SELP/COL3A1/P2RY1/PROS1/CEACAM1/ITGA2/F2R/FN1/CAV1/TFPI2/THBD/TFPI/THBS1/SH2B3/ENTPD1/DGKH/PDGFB/GNAQ/IL6ST/MYH9/PIK3CA/CD59/FLNA/CD36/RAB27A/VCL/PLSCR1/FZD6/CD9/F11R/MYL12A/JMJD1C	36
GO:0001933	negative regulation of protein phosphorylation	47/988	342/18722	1.72495561030693e-09	1.07799578846476e-07	PTPRB/FABP4/LRP6/HEG1/CD109/RASIP1/CEACAM1/HYAL2/WWTR1/HHEX/SMAD6/ENG/CAV1/PDE4D/SH3BP5/ANGPT1/PPM1F/SH2B3/PKIG/RB1/DNAJC10/PKN1/SOCS3/GNAQ/CALM1/DUSP1/AIDA/TGFB1/DUSP6/PRKAR1A/PLPP3/IGFBP3/TRIB2/PARP14/PTEN/HIPK3/ADAR/NR2F2/CTDSP2/APC/SPAG9/SOCS4/PAK2/CTDSP1/CBLB/PLEC/PRKAR2A	47
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	48/988	355/18722	1.99724515923452e-09	1.23364724254114e-07	CDH5/VIM/SPTBN1/CLDN5/ACVRL1/COL3A1/HOXA13/LRRC32/CD109/WWTR1/SMAD6/ENG/CAV1/BMPR2/CAV2/FKBP1A/THBS1/ID1/NOTCH1/FSTL1/TGFBR2/SKIL/SMAD5/LTBP1/SMAD1/PXN/SMURF2/CRIM1/HIPK2/XIAP/PML/TGFB1/SKI/FERMT2/SDCBP/CREB1/STAT3/HTRA1/ZMIZ1/EGR1/LTBP3/SMAD2/HES1/PTK2/HSPA1A/SMAD4/JUN/CTDSPL2	48
GO:0030336	negative regulation of cell migration	47/988	344/18722	2.09109178269671e-09	1.2767677643316e-07	CLDN5/BST2/MMRN2/ACVRL1/MEOX2/TIE1/COL3A1/DACH1/HYAL2/MEF2C/ENG/JAG1/ADAM15/ANGPT2/PLCB1/DLC1/THBS1/NOTCH1/VASH1/IFITM1/RHOB/RGCC/PHLDB2/TIMP1/LIMCH1/DUSP1/TGFB1/GJA1/CD200/TP53INP1/IGFBP3/KLF4/PTEN/RRAS/RHOA/PTPRM/STAT3/LRCH1/PTPRG/NR2F2/VCL/CLIC4/STARD13/ATP2B4/SP100/WASL/SYNJ2BP	47
GO:0040013	negative regulation of locomotion	51/988	391/18722	2.19944837986288e-09	1.32766702202632e-07	CLDN5/BST2/MMRN2/ACVRL1/MEOX2/TIE1/COL3A1/DACH1/HYAL2/MEF2C/ENG/JAG1/ADAM15/ANGPT2/PLCB1/DLC1/THBS1/NOTCH1/VASH1/IFITM1/RHOB/RGCC/PHLDB2/NRP1/TIMP1/LIMCH1/DUSP1/TGFB1/GJA1/CD200/TP53INP1/IGFBP3/KLF4/PTEN/RRAS/RHOA/PTPRM/STAT3/LRCH1/PTPRG/NR2F2/SEMA3F/VCL/CLIC4/STARD13/ATP2B4/CTNNA1/SP100/CRK/WASL/SYNJ2BP	51
GO:0060537	muscle tissue development	52/988	403/18722	2.23617547300838e-09	1.33467012501354e-07	EDN1/IGF1/MEOX2/HEG1/S1PR1/HLX/SORBS2/EFNB2/MEF2C/ENG/CAV1/CAV2/FKBP1A/RCAN1/NOTCH1/TGFBR2/IGF2/ITGB1/SMAD5/SMAD1/FLNB/MEF2A/VAMP5/DDX17/PDLIM5/RB1/TGFB1/GJA1/CFLAR/PRKAR1A/PTEN/RHOA/SKI/CREB1/NR2F2/PKD2/EGR1/TBX3/FOXN2/PPP3CA/PRKAA1/GJA5/NR1D2/PLEC/CDC42/MAPK1/ID2/MYL6/BTG2/SMAD4/SAV1/ZMPSTE24	52
GO:0051056	regulation of small GTPase mediated signal transduction	43/988	302/18722	2.87831074118446e-09	1.69884296190798e-07	ARHGAP29/IGF1/HEG1/CGNL1/COL3A1/PREX2/FGD5/RASIP1/ARHGEF15/F2R/RALGAPA2/LPAR6/RASA4/DLC1/ARHGEF12/NOTCH1/ITGB1/FGD4/ARHGAP28/NRP1/PLEKHG1/ARHGAP31/RGL2/RDX/OGT/MAP4K4/ARPP19/CYTH1/ABCA1/TNFAIP1/STARD13/ARHGAP5/PPP2CB/F11R/SHOC2/CRK/MYO9A/ARHGEF3/ARFGEF3/RALGAPB/SOS2/SOS1/ARHGAP17	43
GO:0061437	renal system vasculature development	12/988	27/18722	3.63516308198145e-09	2.09891155342233e-07	PECAM1/CD34/TEK/ANGPT2/ANGPT1/NOTCH1/NRP1/PDGFB/CFLAR/PKD2/EGR1/HES1	12
GO:0061440	kidney vasculature development	12/988	27/18722	3.63516308198145e-09	2.09891155342233e-07	PECAM1/CD34/TEK/ANGPT2/ANGPT1/NOTCH1/NRP1/PDGFB/CFLAR/PKD2/EGR1/HES1	12
GO:0120193	tight junction organization	20/988	80/18722	4.00623961849337e-09	2.28829514553083e-07	PECAM1/CDH5/RAMP2/CLDN5/ESAM/CLDN11/TJP1/MTDH/MPDZ/PRKCH/GJA1/MYO1C/APC/PAK2/F11R/PLEC/PDCD6IP/ROCK2/STRN/ROCK1	20
GO:0022407	regulation of cell-cell adhesion	55/988	448/18722	4.70189454170945e-09	2.65707061761283e-07	FCGR2B/IGF1/SELP/PODXL/LRRC32/NOTCH4/HLX/CEACAM1/CAV1/JAG1/MAGI1/ETS1/PIEZO1/HLA-E/HLA-A/TJP1/PPM1F/NOTCH1/SH2B3/TGFBR2/IGF2/RGCC/B2M/CD81/LGALS1/MDK/YES1/JAK1/EFNB1/IL6ST/TGFB1/PRKAR1A/PLPP3/FYN/PIK3CA/KLF4/TNFRSF14/NFAT5/RDX/MYO10/RHOA/FXYD5/ZMIZ1/RC3H1/CD44/CD9/F11R/CBLB/WNK1/CD46/HES1/PTK2/KIFAP3/HSPH1/BCL10	55
GO:0003018	vascular process in circulatory system	39/988	263/18722	4.93851294104657e-09	2.76140849924625e-07	CDH5/RAMP2/CLDN5/EDN1/PLVAP/TEK/LEPR/ECE1/P2RY1/CEACAM1/F2R/NPR1/CAV1/BMPR2/ITGA1/FABP5/KLF2/TJP1/ANGPT1/SLC38A2/DOCK4/YES1/SLC12A2/ADRB1/TGFB1/GJA1/CD36/RHOA/SLC44A1/FERMT2/PIK3C2A/SLC2A1/ATP2B4/GJA5/SLC2A3/PLEC/ROCK2/ROCK1/SLC16A2	39
GO:0018212	peptidyl-tyrosine modification	49/988	378/18722	5.59466807415693e-09	3.09571633436683e-07	PECAM1/KDR/IGF1/TIE1/TEK/ENPP2/HYAL2/ITGA5/CAV1/FGFR1/SH3BP5/PRKCE/PEAK1/ANGPT1/NEDD9/SH2B3/IGF2/CD81/NRP1/PDGFB/HIPK2/APP/YES1/JAK1/SOCS3/TTL/SHC1/IL6ST/TGFB1/FYN/PARP14/TNFRSF14/CD36/ABI2/EIF2AK2/HIPK3/PARP9/EHD4/HIPK1/IQGAP1/CD44/SOCS4/EFEMP1/PAK2/CBLB/HES1/ARL2BP/DYRK1A/PTK2	49
GO:0120192	tight junction assembly	19/988	74/18722	6.05672052078573e-09	3.31683499035194e-07	PECAM1/CDH5/RAMP2/CLDN5/ESAM/CLDN11/TJP1/MTDH/MPDZ/PRKCH/GJA1/MYO1C/APC/PAK2/F11R/PDCD6IP/ROCK2/STRN/ROCK1	19
GO:0031331	positive regulation of cellular catabolic process	53/988	427/18722	6.15055541932702e-09	3.33385208035359e-07	KDR/IGF1/ZBTB20/CAV1/FOXO1/MSN/SPTLC2/CLU/MTDH/RNF144B/CD81/ZFP36L1/APP/PABPC1/CPT1A/TP53INP1/TRIB2/ATXN3/PTEN/RNF19A/RDX/HIF1A/PIK3C2A/ZFP36/RALB/TNRC6B/CELF1/CNOT6L/ZC3HAV1/RC3H1/CSNK1A1/HECTD1/TNFRSF1B/SOCS4/ZFP36L2/TRIM13/PRKAA1/CNOT8/ATF6/WAC/DTX3L/SH3GLB1/ROCK2/TNRC6A/ROCK1/CNOT2/PTK2/HSPA1A/PIAS1/BTG2/PLK2/TMTC3/PAFAH1B2	53
GO:0001935	endothelial cell proliferation	32/988	193/18722	7.72592436415479e-09	4.14546567902932e-07	SPARC/EGFL7/APLNR/CD34/KDR/ACVRL1/TIE1/TEK/VEGFC/LOXL2/MEF2C/CAV1/BMPR2/FGFR1/CAV2/SCARB1/THBS1/VASH1/IGF2/RGCC/NRP1/PDGFB/MDK/GJA1/AKT3/HIF1A/PTPRM/STAT3/GATA2/NR2F2/NRAS/SYNJ2BP	32
GO:0008360	regulation of cell shape	28/988	154/18722	8.31699454692171e-09	4.40082959437803e-07	KDR/PALMD/P2RY1/FGD5/RHOJ/CDC42EP5/PLXND1/FN1/MSN/PARVB/DLC1/FGD4/RHOB/FYN/PLXNA2/MYH9/RDX/MYO10/RHOA/FERMT2/MKLN1/MYL12B/F11R/CRK/PHIP/MYL12A/PTK2/ZMPSTE24	28
GO:1901653	cellular response to peptide	47/988	359/18722	8.36754120919016e-09	4.40082959437803e-07	VIM/FCGR2B/EDN1/IGF1/CRHBP/KL/CEACAM1/GRB14/CAV1/FOXO1/CAV2/KLF2/ID1/IGF2/PXN/ZFP36L1/PIK3R3/PDK4/APP/LEPROTL1/GNAI2/SOCS3/SHC1/GJA1/CFLAR/FYN/TBC1D4/PIK3CA/KLF4/PTEN/CD36/KLF3/OGT/PIK3C2A/CREB1/STAT3/MYO1C/APC/LEPROT/PRKAA1/PTPRA/CRK/PHIP/KLF10/ROCK2/ROCK1/PTK2	47
GO:0060840	artery development	22/988	100/18722	8.88419692733248e-09	4.58183049300875e-07	APLNR/ACVRL1/ADGRF5/HOXA13/FOXF1/PLXND1/SMAD6/ENG/BMPR2/JAG1/NOTCH1/NRP1/MDK/LUZP1/AKT3/AP2B1/PKD2/ZMIZ1/HECTD1/GJA5/HES1/ADAMTS6	22
GO:0110020	regulation of actomyosin structure organization	22/988	100/18722	8.88419692733248e-09	4.58183049300875e-07	EDN1/CGNL1/S1PR1/ARHGEF15/DLC1/TJP1/PPM1F/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/RHOA/FERMT2/CCDC88A/PAK2/F11R/ROCK2/ROCK1/CDC42/SMAD4	22
GO:0048762	mesenchymal cell differentiation	36/988	236/18722	9.00620904665149e-09	4.60009446690507e-07	EDN1/LRP6/NOTCH4/LOXL2/WWTR1/MEF2C/FN1/ENG/JAG1/FGFR1/ADAM15/NOTCH1/TGFBR2/RGCC/PHLDB2/NRP1/DDX17/MDK/EFNB1/TGFB1/PTEN/FLNA/HIF1A/FERMT2/SDCBP/PHACTR4/SEMA3F/RTN4/TBX3/PPP3R1/SMAD2/HES1/ROCK2/ROCK1/MAPK1/SMAD4	36
GO:0001655	urogenital system development	45/988	338/18722	1.03578095689274e-08	5.24006518382307e-07	PECAM1/CD34/TEK/NFIA/PODXL/HOXA13/FOXF1/DCHS1/HYAL2/WWTR1/MEF2C/COL4A1/PLXND1/SMAD6/PCSK5/JAG1/ID3/ANGPT2/NID1/ANGPT1/LAMB2/NOTCH1/SMAD5/SMAD1/NRP1/PDGFB/SULF2/CFLAR/AP2B1/PTEN/RHOA/GATA2/PKD2/ACAT1/EGR1/FEM1B/IQGAP1/SMAD2/NIPBL/HES1/SMAD4/ADAMTS6/SEC61A1/MTSS1/ZMPSTE24	45
GO:0018108	peptidyl-tyrosine phosphorylation	48/988	375/18722	1.20655684709218e-08	6.04644336957894e-07	PECAM1/KDR/IGF1/TIE1/TEK/ENPP2/HYAL2/ITGA5/CAV1/FGFR1/SH3BP5/PRKCE/PEAK1/ANGPT1/NEDD9/SH2B3/IGF2/CD81/NRP1/PDGFB/HIPK2/APP/YES1/JAK1/SOCS3/SHC1/IL6ST/TGFB1/FYN/PARP14/TNFRSF14/CD36/ABI2/EIF2AK2/HIPK3/PARP9/EHD4/HIPK1/IQGAP1/CD44/SOCS4/EFEMP1/PAK2/CBLB/HES1/ARL2BP/DYRK1A/PTK2	48
GO:1903034	regulation of response to wounding	29/988	167/18722	1.33276029310277e-08	6.61646979155319e-07	CD34/EDN1/CD109/PROS1/CEACAM1/F2R/SCARF1/CAV1/THBD/TFPI/PRKCE/THBS1/SH2B3/ITGB1/PHLDB2/PDGFB/GIT1/MDK/SLC12A2/GJA1/PLPP3/KLF4/PTEN/FLNA/CD36/FERMT2/CD9/CRK/PTK2	29
GO:0070830	bicellular tight junction assembly	18/988	70/18722	1.47914723706749e-08	7.27521307713195e-07	PECAM1/CDH5/RAMP2/CLDN5/ESAM/CLDN11/TJP1/MTDH/PRKCH/GJA1/MYO1C/APC/PAK2/F11R/PDCD6IP/ROCK2/STRN/ROCK1	18
GO:0034332	adherens junction organization	15/988	49/18722	1.79243042584936e-08	8.73522057074478e-07	CDH5/RAMP2/DCHS1/TJP1/JAM3/RDX/FERMT2/ADAM10/VCL/HIPK1/ADD1/PAK2/PLEC/CDC42/MTSS1	15
GO:0006898	receptor-mediated endocytosis	36/988	244/18722	2.19461716405407e-08	1.05980057958684e-06	RAMP2/FCGR2B/CALCRL/LRP6/RAMP3/BICD1/CEACAM1/SCARF1/HSPG2/CAV1/HIP1/CAV2/SYT11/ANGPT1/TGFBR2/ITGB1/STAB1/CLU/B2M/CD81/CANX/PDLIM7/SCARB2/ITSN2/AP2B1/CD36/SDCBP/MKLN1/CTTN/PPP3R1/PICALM/CD9/WASL/HNRNPK/NEDD4/RAB5A	36
GO:0003231	cardiac ventricle development	24/988	123/18722	2.32243750956076e-08	1.11142234691773e-06	APLNR/CPE/HEG1/HOXA13/FOXF1/MEF2C/SMAD6/ENG/BMPR2/JAG1/FKBP1A/NOTCH1/TGFBR2/TGFB1/LUZP1/AP2B1/HIF1A/TBX3/HECTD1/GJA5/HES1/SMAD4/SAV1/ZMPSTE24	24
GO:2001214	positive regulation of vasculogenesis	8/988	12/18722	2.39562798854514e-08	1.13621213170998e-06	CD34/RAMP2/KDR/CEACAM1/RIN2/RRAS/RAPGEF2/RAP1A	8
GO:2001212	regulation of vasculogenesis	9/988	16/18722	2.50391110049373e-08	1.17705980228519e-06	CD34/RAMP2/KDR/CEACAM1/RIN2/RRAS/RAPGEF2/EMP2/RAP1A	9
GO:0072001	renal system development	41/988	302/18722	2.68053542920467e-08	1.24903545613467e-06	PECAM1/CD34/TEK/NFIA/PODXL/FOXF1/DCHS1/HYAL2/WWTR1/MEF2C/COL4A1/PLXND1/SMAD6/PCSK5/JAG1/ID3/ANGPT2/NID1/ANGPT1/LAMB2/NOTCH1/SMAD5/SMAD1/NRP1/PDGFB/SULF2/CFLAR/AP2B1/RHOA/PKD2/ACAT1/EGR1/IQGAP1/SMAD2/NIPBL/HES1/SMAD4/ADAMTS6/SEC61A1/MTSS1/ZMPSTE24	41
GO:0003170	heart valve development	17/988	65/18722	2.8212013323815e-08	1.30314969370526e-06	APLNR/TIE1/DCHS1/MEF2C/SMAD6/BMPR2/JAG1/NOTCH1/TGFBR2/RB1/TGFB1/HECTD1/TNFRSF1B/GJA5/ROCK2/ROCK1/SMAD4	17
GO:0007162	negative regulation of cell adhesion	41/988	303/18722	2.94623378643385e-08	1.34917188564971e-06	FCGR2B/ACVRL1/PODXL/LRRC32/NOTCH4/HLX/CEACAM1/FZD4/PLXND1/JAG1/ADAM15/ANGPT2/DLC1/THBS1/ANGPT1/PPM1F/NOTCH1/SH2B3/RGCC/PHLDB2/ACTN4/LGALS1/MDK/DUSP1/JAM3/TGFB1/PRKAR1A/PLXNA2/KLF4/TNFRSF14/PTEN/RDX/RHOA/MAP4K4/ADAM10/FXYD5/RC3H1/CD9/CBLB/WNK1/PTK2	41
GO:0031532	actin cytoskeleton reorganization	22/988	107/18722	3.29836111226905e-08	1.49751232721139e-06	ESAM/TEK/S1PR1/PDLIM4/PARVB/CDC42BPA/TJP1/NEDD9/NRP1/MDK/SHC1/MYH9/FLNA/RHOA/MKLN1/CTTN/F11R/PLEC/GSN/CDC42BPB/RALA/CDC42	22
GO:0003151	outflow tract morphogenesis	18/988	74/18722	3.79283908208738e-08	1.70742044102103e-06	CLDN5/SOX18/MEF2C/PLXND1/SMAD6/ENG/BMPR2/JAG1/NOTCH1/TGFBR2/NRP1/HIF1A/TBX3/GJA5/NIPBL/ATF2/HES1/SMAD4	18
GO:0034446	substrate adhesion-dependent cell spreading	22/988	108/18722	3.93863879494076e-08	1.75815540157356e-06	TEK/LIMS2/FZD4/FN1/PARVB/PEAK1/LAMB2/NEDD9/PXN/NRP1/ACTN4/MDK/LAMC1/LIMS1/FLNA/RHOA/FERMT2/ARHGEF7/CRK/CDC42/PTK2/DOCK1	22
GO:0048872	homeostasis of number of cells	38/988	272/18722	4.00612149835865e-08	1.77337644994009e-06	ADGRF5/MYCT1/F2R/MEF2C/EPAS1/ETS1/THRA/KLF2/NOTCH1/FSTL1/SH2B3/SKIL/SMAD5/B2M/ZFP36L1/KMT2E/HIPK2/RB1/CDK6/PKN1/JAM3/AKT3/TMOD3/PDE4B/ISG15/HIF1A/ZFP36/STAT3/GATA2/ADAR/RC3H1/LIPA/PTBP3/SOS2/SOS1/HSPA1A/ID2/BCL10	38
GO:0051492	regulation of stress fiber assembly	20/988	91/18722	4.25987060695001e-08	1.86092813542625e-06	CGNL1/S1PR1/ARHGEF15/DLC1/TJP1/PPM1F/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/RHOA/FERMT2/CCDC88A/PAK2/F11R/ROCK2/ROCK1/CDC42	20
GO:0072659	protein localization to plasma membrane	39/988	284/18722	4.27396898573047e-08	1.86092813542625e-06	RAMP2/SPTBN1/LRP6/SLC9A3R2/RAMP3/P2RY1/TMEM88/EHD2/DCHS1/PRKCE/MACF1/TSPAN14/PPP2R5A/ITGB1/CD81/KIF5B/VAMP5/PRKCH/TGFB1/EXOC5/STX3/ACSL3/FLNA/RDX/EHD4/RAPGEF2/ATP2B4/EMP2/CCDC88A/PICALM/HECTD1/SEC23A/F11R/MYL12A/RAB11A/ROCK2/ROCK1/GOLGA7/RAP1A	39
GO:0061298	retina vasculature development in camera-type eye	9/988	17/18722	5.0710917840359e-08	2.1900519964877e-06	ACVRL1/RHOJ/FZD4/ARHGEF15/COL4A1/BMPR2/NRP1/HIF1A/CLIC4	9
GO:0001837	epithelial to mesenchymal transition	27/988	157/18722	5.17432375316261e-08	2.21661353038708e-06	LRP6/NOTCH4/LOXL2/WWTR1/ENG/JAG1/FGFR1/ADAM15/NOTCH1/TGFBR2/RGCC/PHLDB2/DDX17/MDK/TGFB1/PTEN/FLNA/HIF1A/FERMT2/SDCBP/RTN4/TBX3/PPP3R1/SMAD2/ROCK2/ROCK1/SMAD4	27
GO:0043536	positive regulation of blood vessel endothelial cell migration	18/988	76/18722	5.91655672259699e-08	2.51429994483482e-06	KDR/VEGFC/RHOJ/FGFR1/ETS1/THBS1/ANGPT1/HDAC7/TMSB4X/NRP1/PDGFB/MAP3K3/TGFB1/AKT3/HIF1A/PIK3C2A/GATA2/PLK2	18
GO:0030218	erythrocyte differentiation	23/988	120/18722	6.42214048756659e-08	2.70749287856776e-06	ADGRF5/EPAS1/ETS1/THRA/KLF2/SH2B3/SMAD5/B2M/ZFP36L1/KMT2E/HIPK2/RB1/CDK6/TMOD3/ISG15/HIF1A/ZFP36/STAT3/GATA2/ADAR/PTBP3/HSPA1A/ID2	23
GO:0001936	regulation of endothelial cell proliferation	29/988	179/18722	6.51997477535699e-08	2.72709496115719e-06	SPARC/EGFL7/APLNR/KDR/ACVRL1/TIE1/TEK/VEGFC/MEF2C/CAV1/BMPR2/FGFR1/CAV2/THBS1/VASH1/IGF2/RGCC/NRP1/PDGFB/MDK/GJA1/AKT3/HIF1A/PTPRM/STAT3/GATA2/NR2F2/NRAS/SYNJ2BP	29
GO:0042692	muscle cell differentiation	47/988	384/18722	6.87172810214274e-08	2.85176716238924e-06	APLNR/RAMP2/EDN1/JAM2/IGF1/EHD2/FOXF1/SORBS2/EFNB2/MEF2C/TANC1/ENG/BMPR2/CAV2/PIEZO1/RCAN1/NOTCH1/IGF2/ITGB1/ATP11A/CD81/SMAD1/MEF2A/PDGFB/ACTN4/PDLIM5/RB1/TGFB1/CFLAR/PRKAR1A/MYH9/TMOD3/CAPN2/DYSF/SKI/QKI/TBX3/SPAG9/CD9/PPP3CA/PLEC/HES1/ID2/PIAS1/SMAD4/MYOF/ZMPSTE24	47
GO:0060562	epithelial tube morphogenesis	42/988	325/18722	7.52447312761834e-08	3.09594383415752e-06	APLNR/EDN1/KDR/ACVRL1/TIE1/SOX18/PODXL/NOTCH4/RASIP1/FOXF1/DCHS1/MEF2C/COL4A1/PLXND1/ENG/FOXP1/DLC1/NOTCH1/TGFBR2/RHOB/NRP1/MDK/PML/TGFB1/LUZP1/MIB1/RHOA/HIF1A/SKI/PHACTR4/PKD2/CLIC4/STARD13/TBX3/PPP3R1/FZD6/HECTD1/RALA/HES1/SMAD4/BCL10/MTSS1	42
GO:0002042	cell migration involved in sprouting angiogenesis	20/988	94/18722	7.5766697748584e-08	3.09594383415752e-06	KDR/MMRN2/MEOX2/CLEC14A/RHOJ/EFNB2/THBS1/HDAC7/NOTCH1/ITGB1/PIK3R3/NRP1/MAP3K3/AKT3/KLF4/RHOA/PIK3C2A/GATA2/STARD13/PLK2	20
GO:0019079	viral genome replication	24/988	131/18722	8.23003950102544e-08	3.33724960530131e-06	IFI27/BST2/NFIA/IFITM2/IFITM3/NOTCH1/IFI16/IFITM1/STOM/PABPC1/OAS2/MX1/ISG15/EIF2AK2/ADAR/PKN2/PCBP2/ZC3HAV1/FAM111A/PLSCR1/CTBP2/ROCK2/CDC42/RAB5A	24
GO:0006470	protein dephosphorylation	38/988	281/18722	9.56725974226485e-08	3.85009725385688e-06	CDH5/PTPRB/NUAK1/FKBP1A/ITGA1/DLC1/RCAN1/PPP2R5A/PPM1F/GNAI2/CTTNBP2NL/CALM1/DUSP1/TGFB1/DUSP6/CDC25B/PPP2R2A/PTEN/MTMR6/PTPRM/ARPP19/HSP90B1/PTPRG/CTDSP2/PPP3R1/PTP4A2/PPP2CB/PPP3CA/PTPN14/CTDSP1/PTPRA/PPP2R5E/ROCK2/ROCK1/PTPN12/PPP1R12A/CTDSPL2/YWHAB	38
GO:0043434	response to peptide hormone	49/988	414/18722	1.03736082080728e-07	4.14320351889342e-06	SPARC/EDN1/CRHBP/LRP6/TEK/KL/CEACAM1/GRB14/TNFSF10/HHEX/CAV1/FOXO1/CAV2/IGF2/PXN/ZFP36L1/PIK3R3/TIMP1/PDK4/LEPROTL1/GNAI2/SOCS3/SHC1/GJA1/CFLAR/FYN/TBC1D4/PIK3CA/PTEN/KBTBD2/OGT/PIK3C2A/CREB1/STAT3/EGR1/VPS13C/SLC2A1/MYO1C/APC/IQGAP1/LEPROT/PRKAA1/PTPRA/CRK/PHIP/ROCK2/ROCK1/PTK2/BTG2	49
GO:0033673	negative regulation of kinase activity	34/988	237/18722	1.0787128036055e-07	4.2762107557854e-06	PTPRB/FABP4/LRP6/HEG1/RASIP1/CEACAM1/HYAL2/WWTR1/HHEX/CAV1/SH3BP5/PPP2R5A/PPM1F/SH2B3/PKIG/RB1/PKN1/GNAQ/DUSP1/AIDA/PRKAR1A/TRIB2/PTEN/HIPK3/ADAR/NR2F2/APC/SOCS4/PAK2/CBLB/PLEC/WNK1/MIDN/PRKAR2A	34
GO:0051099	positive regulation of binding	28/988	173/18722	1.11917468186426e-07	4.40374511856513e-06	RAMP2/CLDN5/IGF1/ITGA2/PLXND1/CAV1/CLIC2/FKBP1A/MFNG/B2M/NRP1/HIPK2/APP/RB1/CALM1/TGFB1/HMBOX1/KLF4/SKI/RALB/PARP9/RAPGEF2/ADD1/PPP2CB/CTBP2/DTX3L/HES1/PLK2	28
GO:0061041	regulation of wound healing	24/988	134/18722	1.28512918945173e-07	5.01956342232911e-06	CD34/EDN1/CD109/PROS1/CEACAM1/F2R/CAV1/THBD/TFPI/PRKCE/THBS1/SH2B3/ITGB1/PHLDB2/PDGFB/SLC12A2/GJA1/PLPP3/PTEN/CD36/FERMT2/CD9/CRK/PTK2	24
GO:0030038	contractile actin filament bundle assembly	21/988	106/18722	1.32048465273428e-07	5.08290904009021e-06	CGNL1/S1PR1/ARHGEF15/DLC1/TJP1/PPM1F/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/RHOA/FERMT2/TNFAIP1/CCDC88A/PAK2/F11R/ROCK2/ROCK1/CDC42	21
GO:0043149	stress fiber assembly	21/988	106/18722	1.32048465273428e-07	5.08290904009021e-06	CGNL1/S1PR1/ARHGEF15/DLC1/TJP1/PPM1F/RGCC/ARHGAP28/PHLDB2/PXN/NRP1/LIMCH1/RHOA/FERMT2/TNFAIP1/CCDC88A/PAK2/F11R/ROCK2/ROCK1/CDC42	21
GO:0030856	regulation of epithelial cell differentiation	26/988	154/18722	1.33421849159431e-07	5.09882635061079e-06	CDH5/CLDN5/ACVRL1/ZEB1/CD109/NOTCH4/CEACAM1/WWTR1/CAV1/JAG1/PLCB1/ID1/NOTCH1/ZFP36L1/PRKCH/VEZF1/ZFP36/KIAA1109/VCL/TBX3/ADD1/CCND1/F11R/HES1/ROCK2/ROCK1	26
GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	13/988	42/18722	1.38936532511717e-07	5.27164900501599e-06	SMAD6/ETS1/SMAD1/PDGFB/TGFB1/KLF4/HIF1A/STAT3/GATA2/EGR1/NR3C1/SMAD4/JUN	13
GO:0030099	myeloid cell differentiation	46/988	381/18722	1.42144974533293e-07	5.35513549447415e-06	ADGRF5/FLI1/CD109/CEACAM1/MEF2C/JAG1/FOXP1/EPAS1/ETS1/THRA/KLF2/SNRK/SH2B3/IFI16/TGFBR2/SMAD5/B2M/CD81/ZFP36L1/KMT2E/HIPK2/APP/RB1/CDK6/PML/TGFB1/MYH9/TMOD3/GABPA/ISG15/HIF1A/GLO1/ZFP36/CREB1/STAT3/GATA2/ADAR/LBR/PTBP3/KAT6A/KLF10/PURB/CDC42/HSPA1A/ID2/JUN	46
GO:0050900	leukocyte migration	45/988	369/18722	1.45139522146752e-07	5.42944465946158e-06	PECAM1/CD34/EDN1/JAM2/PLVAP/SELP/S1PR1/VEGFC/ITGA2/MTUS1/MSN/ITGA1/IL1R1/PLCB1/THBS1/ITGB1/CD81/PDGFB/APP/MDK/YES1/SLC12A2/DUSP1/JAM3/CD200/FYN/LYST/MYH9/TNFRSF14/PDE4B/RHOA/ADAM10/LRCH1/MOSPD2/CD9/F11R/CRK/PLEC/WNK1/WASL/ROCK1/CDC42/PTK2/SOS1/MAPK1	45
GO:0007163	establishment or maintenance of cell polarity	32/988	218/18722	1.48766998149143e-07	5.52622583334438e-06	CDH5/TEK/FSCN1/TCF15/FOXF1/MSN/PARVB/ITGB1/RHOB/DST/JAM3/GJA1/MYH9/ACTR2/RHOA/CYTH1/CLIC4/CTNNA1/RUFY3/CRK/MYO9A/GSN/PDCD6IP/CDC42BPB/HES1/MAP4/ROCK2/ROCK1/CDC42/SYNJ2BP/PTK2/AMOTL2	32
GO:0010720	positive regulation of cell development	39/988	298/18722	1.56718178585884e-07	5.7811594767237e-06	CDH5/CLDN5/VEGFC/LIMS2/PLXND1/FN1/BMPR2/MACF1/NEDD9/NOTCH1/SKIL/NRP1/MDK/DICER1/PRKCH/IL6ST/TGFB1/LIMS1/PLXNA2/GDI1/FLNA/ACTR2/HIF1A/FERMT2/NPTN/SPEN/ADD1/RUFY3/ARHGEF7/TNFRSF1B/F11R/CRK/HES1/RAB11A/CDC42/EIF4G2/DOCK1/ID2/NIN	39
GO:0001503	ossification	48/988	408/18722	1.67995257520554e-07	6.15441936516679e-06	SPARC/MGP/IGF1/TEK/KL/S1PR1/VEGFC/CLEC3B/DCHS1/WWTR1/MEF2C/SMAD6/BMPR2/JAG1/THRA/ID3/SRGN/HDAC7/NOTCH1/IGF2/IFITM1/SMAD5/SMAD1/BCOR/GIT1/CRIM1/PDLIM7/CDK6/MDK/CHSY1/IL6ST/TGFB1/ISG15/RHOA/SUN1/HIF1A/SKI/FERMT2/BCAP29/ADAR/NBR1/TPM4/LTBP3/NIPBL/KLF10/PTK2/MAPK1/ZMPSTE24	48
GO:1903829	positive regulation of cellular protein localization	37/988	276/18722	1.76169926906963e-07	6.40968939540952e-06	SPTBN1/RAMP3/BICD1/ABLIM3/HYAL2/WWTR1/MSN/SYT11/PRKCE/ITGB1/CD81/KIF5B/STOM/PRKCH/TGFB1/STX3/FYN/AP2B1/ACSL3/FLNA/RDX/FERMT2/NPTN/PARP9/RTN4/MYO1C/ATP2B4/APC/CCDC88A/IQGAP1/LEPROT/PRKAA1/DTX3L/SH3GLB1/RAB11A/ROCK2/MAPK1	37
GO:1902905	positive regulation of supramolecular fiber organization	31/988	209/18722	1.83013267019166e-07	6.61337737691027e-06	EDN1/ARHGEF15/CDC42EP5/PRKCE/PPM1F/ID1/RGCC/CLU/PXN/NRP1/GIT1/APP/LIMCH1/RB1/NCKAP1/FLNA/ACTR2/RHOA/ABI2/FERMT2/CTTN/MYO1C/CCDC88A/GSN/ROCK2/WASL/CDC42/HSPA1A/DSTN/MTSS1/NIN	31
GO:0007266	Rho protein signal transduction	24/988	137/18722	1.97785527863625e-07	7.098896783862e-06	ARHGAP29/HEG1/COL3A1/RHOJ/RASIP1/F2R/CDC42EP5/LPAR6/DLC1/ARHGEF12/ITGB1/RHOB/NRP1/RHOA/PHACTR4/ABCA1/TNFAIP1/STARD13/ARHGAP5/F11R/ARHGEF3/ROCK2/ROCK1/CDC42	24
GO:0030198	extracellular matrix organization	39/988	301/18722	2.04323983582444e-07	7.28435570999961e-06	COL15A1/RAMP2/TIE1/COL3A1/NDNF/FSCN1/COL18A1/TCF15/LOXL2/FOXF1/COL4A1/ENG/CAV1/TLL1/CAV2/COL4A2/ADAM15/ETS1/NID1/LAMB2/NOTCH1/ITGB1/RGCC/PHLDB2/SULF2/APP/RB1/LAMC1/TGFB1/CFLAR/QSOX1/SERPINH1/ERO1A/HSD17B12/ADAM10/TNFRSF1B/LTBP3/CRTAP/ADAMTS6	39
GO:0001954	positive regulation of cell-matrix adhesion	15/988	58/18722	2.16496994638867e-07	7.66688023681108e-06	KDR/TEK/PPM1F/UTRN/NRP1/CDK6/RIN2/LIMS1/RRAS/CD36/FERMT2/MAP4K4/EMP2/IQGAP1/ROCK1	15
GO:0043062	extracellular structure organization	39/988	302/18722	2.2299244270977e-07	7.84460831572385e-06	COL15A1/RAMP2/TIE1/COL3A1/NDNF/FSCN1/COL18A1/TCF15/LOXL2/FOXF1/COL4A1/ENG/CAV1/TLL1/CAV2/COL4A2/ADAM15/ETS1/NID1/LAMB2/NOTCH1/ITGB1/RGCC/PHLDB2/SULF2/APP/RB1/LAMC1/TGFB1/CFLAR/QSOX1/SERPINH1/ERO1A/HSD17B12/ADAM10/TNFRSF1B/LTBP3/CRTAP/ADAMTS6	39
GO:0051348	negative regulation of transferase activity	36/988	268/18722	2.45095795951268e-07	8.56545307956009e-06	PTPRB/FABP4/LRP6/HEG1/RASIP1/CEACAM1/HYAL2/WWTR1/HHEX/CAV1/SH3BP5/PPP2R5A/PPM1F/SH2B3/PKIG/RB1/PKN1/GNAQ/DUSP1/AIDA/PRKAR1A/TRIB2/PTEN/ZFP36/HIPK3/ADAR/NR2F2/APC/SOCS4/PAK2/CBLB/PLEC/WNK1/DTX3L/MIDN/PRKAR2A	36
GO:0072012	glomerulus vasculature development	10/988	25/18722	2.53145489509191e-07	8.7262200683657e-06	PECAM1/CD34/TEK/ANGPT2/ANGPT1/NOTCH1/PDGFB/CFLAR/EGR1/HES1	10
GO:0006469	negative regulation of protein kinase activity	31/988	212/18722	2.53197856355215e-07	8.7262200683657e-06	PTPRB/FABP4/LRP6/HEG1/RASIP1/CEACAM1/HYAL2/WWTR1/HHEX/CAV1/SH3BP5/PPM1F/SH2B3/PKIG/RB1/PKN1/GNAQ/DUSP1/AIDA/PRKAR1A/TRIB2/PTEN/HIPK3/ADAR/NR2F2/APC/SOCS4/PAK2/CBLB/PLEC/PRKAR2A	31
GO:0034101	erythrocyte homeostasis	23/988	129/18722	2.5462426780811e-07	8.7262200683657e-06	ADGRF5/EPAS1/ETS1/THRA/KLF2/SH2B3/SMAD5/B2M/ZFP36L1/KMT2E/HIPK2/RB1/CDK6/TMOD3/ISG15/HIF1A/ZFP36/STAT3/GATA2/ADAR/PTBP3/HSPA1A/ID2	23
GO:0016525	negative regulation of angiogenesis	25/988	149/18722	2.61791373877286e-07	8.85755272634485e-06	SPARC/CLDN5/TIE1/TEK/NPR1/HSPG2/HHEX/COL4A2/ANGPT2/KLF2/THBS1/VASH1/STAB1/RGCC/SLC12A2/PML/KLF4/GTF2I/PTPRM/ATP2B4/ATF2/ROCK2/ROCK1/SYNJ2BP/PLK2	25
GO:0051592	response to calcium ion	25/988	149/18722	2.61791373877286e-07	8.85755272634485e-06	SPARC/EDN1/CRHBP/S100A16/MEF2C/CAV1/RASA4/SYT11/TXNIP/THBS1/MEF2A/CALM1/DUSP1/GDI1/PKD2/CLIC4/ADD1/IQGAP1/PPP3CA/CCND1/PRKAA1/WNK1/SEC31A/NEDD4/CPNE8	25
GO:0045229	external encapsulating structure organization	39/988	304/18722	2.65214406975698e-07	8.91657550541081e-06	COL15A1/RAMP2/TIE1/COL3A1/NDNF/FSCN1/COL18A1/TCF15/LOXL2/FOXF1/COL4A1/ENG/CAV1/TLL1/CAV2/COL4A2/ADAM15/ETS1/NID1/LAMB2/NOTCH1/ITGB1/RGCC/PHLDB2/SULF2/APP/RB1/LAMC1/TGFB1/CFLAR/QSOX1/SERPINH1/ERO1A/HSD17B12/ADAM10/TNFRSF1B/LTBP3/CRTAP/ADAMTS6	39
GO:0031348	negative regulation of defense response	35/988	258/18722	2.82416703491874e-07	9.43520458458386e-06	A2M/CDH5/FCGR2B/CALCRL/IGF1/TEK/NT5E/CEACAM1/FOXF1/SYT11/HLA-E/HLA-A/HLA-B/SEC14L1/IFI16/GIT1/TSPAN6/RB1/MDK/YES1/SOCS3/CD200/FYN/KLF4/PARP14/ISG15/ZFP36/ADAR/HTRA1/PCBP2/ASH1L/TNFRSF1B/NR1D2/CRK/PLK2	35
GO:0001822	kidney development	38/988	293/18722	2.84970651904013e-07	9.46102564321324e-06	PECAM1/CD34/TEK/PODXL/DCHS1/HYAL2/WWTR1/MEF2C/PLXND1/SMAD6/PCSK5/JAG1/ID3/ANGPT2/NID1/ANGPT1/LAMB2/NOTCH1/SMAD5/SMAD1/NRP1/PDGFB/SULF2/CFLAR/AP2B1/RHOA/PKD2/ACAT1/EGR1/IQGAP1/SMAD2/NIPBL/HES1/SMAD4/ADAMTS6/SEC61A1/MTSS1/ZMPSTE24	38
GO:0003206	cardiac chamber morphogenesis	22/988	121/18722	3.24724560483095e-07	1.07138935732062e-05	APLNR/CPE/HEG1/TEK/FOXF1/MEF2C/SMAD6/ENG/BMPR2/JAG1/ADGRG6/FKBP1A/NOTCH1/TGFBR2/NRP1/TGFB1/HIF1A/TBX3/HES1/SOS1/SMAD4/SAV1	22
GO:2000181	negative regulation of blood vessel morphogenesis	25/988	151/18722	3.40328818582044e-07	1.10909612534222e-05	SPARC/CLDN5/TIE1/TEK/NPR1/HSPG2/HHEX/COL4A2/ANGPT2/KLF2/THBS1/VASH1/STAB1/RGCC/SLC12A2/PML/KLF4/GTF2I/PTPRM/ATP2B4/ATF2/ROCK2/ROCK1/SYNJ2BP/PLK2	25
GO:2001236	regulation of extrinsic apoptotic signaling pathway	25/988	151/18722	3.40328818582044e-07	1.10909612534222e-05	IGF1/TNFSF10/HYAL2/CAV1/FGFR1/THBS1/SKIL/NRP1/PEA15/PML/CFLAR/FYN/ZMYND11/PTEN/ITGA6/CYLD/RB1CC1/CTTN/FEM1B/CTNNA1/SP100/PAK2/PHIP/HSPA1A/BCL10	25
GO:0016055	Wnt signaling pathway	50/988	444/18722	3.59686935232331e-07	1.1650347560696e-05	IGFBP4/CPE/RSPO3/LRP6/SOX7/TMEM88/FZD4/ADGRA2/NXN/WWTR1/HHEX/CAV1/MACF1/DIXDC1/NOTCH1/RBMS3/SULF2/SMURF2/MDFIC/APP/XIAP/CCNY/MDK/GNAQ/CTNND1/TGFB1/PLPP3/KLF4/PTEN/RHOA/SKI/FERMT2/CYLD/PKD2/EGR1/FZD6/CSNK1A1/APC/TBL1XR1/CCND1/G3BP1/PRKAA1/WNK1/STRN/DAAM1/CDC42/RNF213/AMOTL2/CSNK1G3/RAB5A	50
GO:0003279	cardiac septum development	20/988	103/18722	3.68268783888168e-07	1.18560229091755e-05	APLNR/HEG1/HOXA13/PLXND1/SMAD6/ENG/BMPR2/JAG1/NOTCH1/TGFBR2/NRP1/LUZP1/AP2B1/TBX3/HECTD1/GJA5/HES1/SMAD4/ADAMTS6/SAV1	20
GO:1901343	negative regulation of vasculature development	25/988	152/18722	3.87274684160673e-07	1.23927898931415e-05	SPARC/CLDN5/TIE1/TEK/NPR1/HSPG2/HHEX/COL4A2/ANGPT2/KLF2/THBS1/VASH1/STAB1/RGCC/SLC12A2/PML/KLF4/GTF2I/PTPRM/ATP2B4/ATF2/ROCK2/ROCK1/SYNJ2BP/PLK2	25
GO:0032535	regulation of cellular component size	45/988	382/18722	3.92854957973479e-07	1.24462440561114e-05	SPTBN1/EDN1/ESAM/KANK3/CDC42EP5/FN1/BMPR2/MSN/PRKCE/MACF1/SPTAN1/TMSB4X/TMEM123/ARHGAP28/NRP1/NCKAP1/SLC12A2/TTL/DPYSL2/TMSB10/AKT3/PIK3CA/TMOD3/PTEN/GDI1/RDX/ACTR2/RHOA/ABI2/CREB1/SEMA3F/RB1CC1/RTN4/CTTN/MYO1C/ADD1/PICALM/RUFY3/GSN/RAB11A/CLCN3/WASL/EIF4G2/DSTN/RAB5A	45
GO:0072006	nephron development	24/988	142/18722	3.93631212617982e-07	1.24462440561114e-05	PECAM1/CD34/TEK/PODXL/DCHS1/WWTR1/MEF2C/JAG1/ANGPT2/NID1/ANGPT1/LAMB2/NOTCH1/PDGFB/SULF2/CFLAR/PKD2/ACAT1/EGR1/IQGAP1/HES1/SMAD4/SEC61A1/MTSS1	24
GO:1990778	protein localization to cell periphery	41/988	333/18722	4.01281604660504e-07	1.261306440211e-05	RAMP2/SPTBN1/LRP6/SLC9A3R2/RAMP3/P2RY1/TMEM88/EHD2/DCHS1/CAV1/PRKCE/MACF1/TSPAN14/PPP2R5A/ITGB1/CD81/KIF5B/VAMP5/PRKCH/TGFB1/EXOC5/STX3/ACSL3/FLNA/RDX/ADAM10/EHD4/RAPGEF2/ATP2B4/EMP2/CCDC88A/PICALM/HECTD1/SEC23A/F11R/MYL12A/RAB11A/ROCK2/ROCK1/GOLGA7/RAP1A	41
GO:0198738	cell-cell signaling by wnt	50/988	446/18722	4.12202308240965e-07	1.28801097728e-05	IGFBP4/CPE/RSPO3/LRP6/SOX7/TMEM88/FZD4/ADGRA2/NXN/WWTR1/HHEX/CAV1/MACF1/DIXDC1/NOTCH1/RBMS3/SULF2/SMURF2/MDFIC/APP/XIAP/CCNY/MDK/GNAQ/CTNND1/TGFB1/PLPP3/KLF4/PTEN/RHOA/SKI/FERMT2/CYLD/PKD2/EGR1/FZD6/CSNK1A1/APC/TBL1XR1/CCND1/G3BP1/PRKAA1/WNK1/STRN/DAAM1/CDC42/RNF213/AMOTL2/CSNK1G3/RAB5A	50
GO:0071900	regulation of protein serine/threonine kinase activity	43/988	359/18722	4.50982456020454e-07	1.40094667039804e-05	EDN1/LRP6/HEG1/RASIP1/FZD4/HYAL2/HHEX/CAV1/BMPR2/FGFR1/THBS1/MAP4K2/SH2B3/IGF2/RGCC/PKIG/PDGFB/SASH1/RB1/CCNY/CALM1/DUSP1/AIDA/TGFB1/TAOK1/PRKAR1A/MAP3K11/TRIB2/PTEN/RHOA/FERMT2/RALB/HIPK3/NR2F2/PKD2/RAPGEF2/ATP2B4/APC/IQGAP1/CCND1/CCNI/PRKAR2A/CCNT1	43
GO:0035455	response to interferon-alpha	9/988	21/18722	5.06009098310051e-07	1.5537111735393e-05	BST2/IFITM2/IFITM3/IFITM1/IFIT3/EIF2AK2/ADAR/IFNAR1/IFIT2	9
GO:0150105	protein localization to cell-cell junction	9/988	21/18722	5.06009098310051e-07	1.5537111735393e-05	PECAM1/CDH5/CGNL1/TJP1/JAK1/FLNA/VCL/PAK2/F11R	9
GO:0046718	viral entry into host cell	24/988	144/18722	5.13181544939805e-07	1.5666783716783e-05	ITGA2/HYAL2/EFNB2/ITGA5/CAV1/IFITM2/CAV2/SCARB1/IFITM3/ITGB1/IFITM1/CD81/NRP1/LGALS1/SCARB2/KPNA3/LAMP1/TNFRSF14/PLSCR1/F11R/XPR1/GSN/CD46/HSPA1A	24
GO:0030510	regulation of BMP signaling pathway	19/988	96/18722	5.27093932393733e-07	1.59995598221458e-05	CDH5/ACVRL1/HOXA13/SMAD6/ENG/BMPR2/NOTCH1/FSTL1/SKIL/SMURF2/CRIM1/HIPK2/XIAP/SKI/HTRA1/SMAD2/HES1/SMAD4/CTDSPL2	19
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	14/988	54/18722	5.30780399487234e-07	1.60199175117965e-05	NFIB/SMAD6/ETS1/SMAD1/PDGFB/TGFB1/KLF4/HIF1A/STAT3/GATA2/EGR1/NR3C1/SMAD4/JUN	14
GO:0007519	skeletal muscle tissue development	25/988	155/18722	5.66333432888349e-07	1.69964022344797e-05	MEOX2/HLX/MEF2C/CAV1/CAV2/RCAN1/NOTCH1/IGF2/FLNB/VAMP5/DDX17/RB1/TGFB1/CFLAR/RHOA/SKI/NR2F2/EGR1/FOXN2/PPP3CA/PRKAA1/NR1D2/PLEC/MYL6/BTG2	25
GO:0043114	regulation of vascular permeability	13/988	47/18722	5.98800786919022e-07	1.78698302253587e-05	CDH5/RAMP2/CLDN5/PLVAP/TEK/CEACAM1/NPR1/TJP1/ANGPT1/YES1/TGFB1/FERMT2/PLEC	13
GO:1902904	negative regulation of supramolecular fiber organization	26/988	166/18722	6.0738833012524e-07	1.8024842511873e-05	CDH5/SPTBN1/CGNL1/S1PR1/KANK3/DLC1/SPTAN1/TJP1/TMSB4X/ARHGAP28/CLU/PHLDB2/TAOK1/TMSB10/PIK3CA/TMOD3/RDX/ADD1/APC/ARHGEF7/PAK2/F11R/GSN/DYRK1A/SMAD4/CAMSAP2	26
GO:0003179	heart valve morphogenesis	14/988	55/18722	6.77709501712173e-07	1.98894633872656e-05	TIE1/DCHS1/MEF2C/SMAD6/BMPR2/JAG1/NOTCH1/TGFBR2/RB1/TGFB1/GJA5/ROCK2/ROCK1/SMAD4	14
GO:0061614	pri-miRNA transcription by RNA polymerase II	14/988	55/18722	6.77709501712173e-07	1.98894633872656e-05	NFIB/SMAD6/ETS1/SMAD1/PDGFB/TGFB1/KLF4/HIF1A/STAT3/GATA2/EGR1/NR3C1/SMAD4/JUN	14
GO:0002262	myeloid cell homeostasis	25/988	157/18722	7.25151052153439e-07	2.11648482914234e-05	ADGRF5/EPAS1/ETS1/THRA/KLF2/SH2B3/SMAD5/B2M/ZFP36L1/KMT2E/HIPK2/RB1/CDK6/JAM3/TMOD3/PDE4B/ISG15/HIF1A/ZFP36/STAT3/GATA2/ADAR/PTBP3/HSPA1A/ID2	25
GO:0031346	positive regulation of cell projection organization	42/988	353/18722	7.32514027887694e-07	2.12629208532209e-05	NDNF/FSCN1/FZD4/ITGA2/SCARF1/ENPP2/CDC42EP5/PLXND1/FN1/BMPR2/AGRN/MACF1/SKIL/NRP1/NCKAP1/MDK/SCARB2/CFLAR/FYN/PLXNA2/PIK3CA/SETX/GDI1/FLNA/ACTR2/ITGA6/ABI2/NPTN/RAPGEF2/ENC1/APC/CCDC88A/IQGAP1/RUFY3/ARHGEF7/RALA/RAB11A/WASL/CDC42/EIF4G2/RAP1A/NIN	42
GO:0048638	regulation of developmental growth	40/988	330/18722	8.3248243486259e-07	2.40334059455982e-05	EDN1/IGF1/HLX/MEF2C/FN1/BMPR2/AGRN/PLCB1/MACF1/NOTCH1/TGFBR2/IGF2/NRP1/APP/ADRB1/TTL/GJA1/ITSN2/DUSP6/DPYSL2/PIK3CA/PTEN/GDI1/PLAC8/CREB1/STAT3/CELF1/SEMA3F/RTN4/CTTN/WWC2/RUFY3/SPAG9/WWC3/NIPBL/RAB11A/EIF4G2/MAPK1/SAV1/ZMPSTE24	40
GO:0001945	lymph vessel development	10/988	28/18722	8.79032126934362e-07	2.52401008555423e-05	ACVRL1/CLEC14A/HEG1/TIE1/SOX18/VEGFC/BMPR2/VASH1/NR2F2/PTPN14	10
GO:0010975	regulation of neuron projection development	49/988	445/18722	9.12535942138332e-07	2.60612415303162e-05	VIM/NDNF/SCARF1/EFNB2/PLXND1/FN1/BMPR2/MACF1/ID1/SKIL/B2M/NRP1/LGALS1/PDLIM5/MDK/SCARB2/CFLAR/FYN/PLXNA2/KLF4/PTEN/SETX/GDI1/FLNA/ACTR2/ITGA6/RHOA/ABI2/MAP4K4/ADAM10/PTPRG/NPTN/SEMA3F/RTN4/RAPGEF2/ENC1/CCDC88A/IQGAP1/RUFY3/THOC2/PPP3CA/PAK2/CRK/RAB11A/EIF4G2/NEDD4/CAMSAP2/RAP1A/NIN	49
GO:1901550	regulation of endothelial cell development	8/988	17/18722	9.27807699631705e-07	2.62155026619341e-05	CDH5/CLDN5/PLCB1/VCL/ADD1/F11R/ROCK2/ROCK1	8
GO:1903140	regulation of establishment of endothelial barrier	8/988	17/18722	9.27807699631705e-07	2.62155026619341e-05	CDH5/CLDN5/PLCB1/VCL/ADD1/F11R/ROCK2/ROCK1	8
GO:0022409	positive regulation of cell-cell adhesion	36/988	284/18722	1.01395929960459e-06	2.84981576693099e-05	IGF1/SELP/PODXL/HLX/CAV1/MAGI1/ETS1/PIEZO1/HLA-E/HLA-A/TJP1/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/JAK1/EFNB1/IL6ST/PLPP3/FYN/PIK3CA/TNFRSF14/NFAT5/MYO10/RHOA/ZMIZ1/CD44/F11R/CD46/HES1/KIFAP3/HSPH1/BCL10	36
GO:0034405	response to fluid shear stress	11/988	35/18722	1.08278960998364e-06	3.01806869067967e-05	MEF2C/SMAD6/TFPI2/ETS1/KLF2/GJA1/KLF4/PKD2/ABCA1/PLEC/MTSS1	11
GO:0002011	morphogenesis of an epithelial sheet	14/988	57/18722	1.08518659623459e-06	3.01806869067967e-05	ACVRL1/CEACAM1/ITGA5/JAG1/NOTCH1/PHLDB2/PTEN/FLNA/RHOA/FERMT2/PHACTR4/CD44/CD151/SOS1	14
GO:0048732	gland development	48/988	436/18722	1.18425981233329e-06	3.27645214745544e-05	NFIB/HOXA13/LIMS2/NOTCH4/HLX/CEACAM1/FOXF1/ITGA2/PLXND1/CAV1/MSN/ETS1/THRA/PAM/NOTCH1/TGFBR2/IGF2/NRP1/SULF2/MDK/CPT1A/PML/TGFB1/CFLAR/OAS2/PIK3CA/PTEN/HIF1A/CREB1/GATA2/PKD2/ACAT1/RB1CC1/RTN4/TBX3/FEM1B/ARHGAP5/ASH1L/CCND1/SMAD2/ATF2/HES1/CDC42/MAPK1/ID2/SMAD4/RAP1A/ZMPSTE24	48
GO:0044409	entry into host	24/988	151/18722	1.24471851740022e-06	3.42587811628496e-05	ITGA2/HYAL2/EFNB2/ITGA5/CAV1/IFITM2/CAV2/SCARB1/IFITM3/ITGB1/IFITM1/CD81/NRP1/LGALS1/SCARB2/KPNA3/LAMP1/TNFRSF14/PLSCR1/F11R/XPR1/GSN/CD46/HSPA1A	24
GO:0043087	regulation of GTPase activity	41/988	348/18722	1.27893853715757e-06	3.50191830380466e-05	ARHGAP29/S1PR1/FGD5/RASIP1/ARHGEF15/F2R/RALGAPA2/PLXND1/PKP4/AGRN/RASA4/CAV2/NEDD9/ITGB1/FGD4/ASAP2/ADRB1/LIMS1/PLXNA2/TBC1D4/RDX/ITGA6/RASAL2/SBF2/FERMT2/MAP4K4/TBC1D15/DOCK9/LRCH1/RAPGEF2/IQGAP1/PICALM/ARHGEF7/F11R/CBLB/CRK/MYO9A/WNK1/RALGAPB/PTK2/RAP1A	41
GO:0051494	negative regulation of cytoskeleton organization	25/988	162/18722	1.31786091011454e-06	3.58998828437356e-05	CDH5/SPTBN1/CGNL1/S1PR1/KANK3/DLC1/SPTAN1/TJP1/TMSB4X/ARHGAP28/PHLDB2/TAOK1/TMSB10/PIK3CA/TMOD3/RDX/ADD1/APC/ARHGEF7/PAK2/F11R/GSN/DYRK1A/SMAD4/CAMSAP2	25
GO:1904019	epithelial cell apoptotic process	21/988	121/18722	1.32505874873689e-06	3.59117962922978e-05	CDH5/RAMP2/KDR/TEK/NDNF/BMPR2/THBS1/ANGPT1/TGFBR2/RGCC/ZFP36L1/RB1/MDK/EXOC5/CFLAR/ZFP36/GATA2/HIPK1/GSN/ATF2/TIA1	21
GO:0045444	fat cell differentiation	31/988	229/18722	1.39901247970253e-06	3.75875925078341e-05	FABP4/ADGRF5/WWTR1/SMAD6/FOXO1/JAG1/PLCB1/CCDC85B/ZFP36L1/ADRB1/ERAP1/ZADH2/TGFB1/TRIB2/KLF4/ERO1A/PLAC8/PSMB8/FERMT2/ZFP36/CREB1/GATA2/CCND1/ZFP36L2/CTBP2/NIPBL/ATF2/HES1/ID2/PIAS1/SAV1	31
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	34/988	264/18722	1.40104354603749e-06	3.75875925078341e-05	PECAM1/IGF1/ENPP2/HYAL2/ITGA5/CAV1/SH3BP5/PRKCE/ANGPT1/NEDD9/SH2B3/IGF2/CD81/NRP1/PDGFB/APP/YES1/SOCS3/SHC1/IL6ST/TGFB1/FYN/PARP14/TNFRSF14/CD36/PARP9/EHD4/IQGAP1/CD44/SOCS4/PAK2/CBLB/HES1/ARL2BP	34
GO:0071604	transforming growth factor beta production	12/988	43/18722	1.46359235709787e-06	3.90683547784115e-05	CD34/LRRC32/FN1/THBS1/LTBP1/CD200/HIF1A/CREB1/LTBP3/CD46/ATF2/SMAD4	12
GO:0010633	negative regulation of epithelial cell migration	20/988	112/18722	1.4834758873724e-06	3.94011195686109e-05	MMRN2/ACVRL1/MEOX2/MEF2C/ANGPT2/THBS1/NOTCH1/VASH1/RGCC/TGFB1/KLF4/PTEN/RHOA/PTPRM/PTPRG/NR2F2/STARD13/ATP2B4/SP100/SYNJ2BP	20
GO:0001946	lymphangiogenesis	8/988	18/18722	1.59272255479349e-06	4.20922498062838e-05	ACVRL1/CLEC14A/TIE1/SOX18/VEGFC/BMPR2/VASH1/PTPN14	8
GO:0050792	regulation of viral process	25/988	164/18722	1.6603923742011e-06	4.36619490979893e-05	BST2/IFITM2/CAV2/IFITM3/NOTCH1/IFI16/IFITM1/STOM/MDFIC/LGALS1/PABPC1/PML/OAS2/MX1/ISG15/ZFP36/EIF2AK2/ADAR/PKN2/ZC3HAV1/FAM111A/PLSCR1/RSF1/TRIM13/GSN	25
GO:0071375	cellular response to peptide hormone stimulus	36/988	290/18722	1.66855716620705e-06	4.36619490979893e-05	EDN1/CRHBP/KL/CEACAM1/GRB14/CAV1/FOXO1/CAV2/IGF2/PXN/ZFP36L1/PIK3R3/PDK4/LEPROTL1/GNAI2/SOCS3/SHC1/CFLAR/FYN/TBC1D4/PIK3CA/PTEN/OGT/PIK3C2A/CREB1/STAT3/MYO1C/APC/LEPROT/PRKAA1/PTPRA/CRK/PHIP/ROCK2/ROCK1/PTK2	36
GO:0052126	movement in host environment	26/988	175/18722	1.70204947913299e-06	4.42429321898417e-05	ITGA2/HYAL2/EFNB2/ITGA5/CAV1/IFITM2/CAV2/SCARB1/IFITM3/ITGB1/IFITM1/CD81/NRP1/LGALS1/SCARB2/PML/KPNA3/LAMP1/TNFRSF14/PLSCR1/F11R/TRIM13/XPR1/GSN/CD46/HSPA1A	26
GO:0007517	muscle organ development	39/988	327/18722	1.70741737554924e-06	4.42429321898417e-05	IGF1/MEOX2/HEG1/S1PR1/LAMA2/TCF15/HLX/MEF2C/ENG/CAV1/CAV2/FKBP1A/ID3/RCAN1/NOTCH1/IGF2/UTRN/FLNB/MEF2A/VAMP5/DDX17/RB1/TGFB1/CFLAR/RHOA/SKI/TCF12/CREB1/NR2F2/EGR1/FOXN2/PPP3CA/PRKAA1/NR1D2/PLEC/KMT5B/MYL6/BTG2/SMAD4	39
GO:1903035	negative regulation of response to wounding	18/988	94/18722	1.73042162246623e-06	4.46213575657311e-05	CD34/EDN1/CD109/PROS1/CEACAM1/THBD/TFPI/THBS1/SH2B3/PHLDB2/PDGFB/GIT1/MDK/SLC12A2/GJA1/PTEN/CD9/CRK	18
GO:0030168	platelet activation	21/988	123/18722	1.74581508601582e-06	4.48008199851017e-05	VWF/SELP/COL3A1/P2RY1/CEACAM1/F2R/FN1/THBD/SH2B3/DGKH/PDGFB/IL6ST/MYH9/PIK3CA/FLNA/VCL/PLSCR1/FZD6/CD9/F11R/MYL12A	21
GO:0014065	phosphatidylinositol 3-kinase signaling	23/988	144/18722	1.89079599736432e-06	4.82880208557658e-05	EDN1/KDR/IGF1/TEK/SELP/PREX2/CEACAM1/F2R/FN1/FGFR1/ANGPT1/ZFP36L1/PDGFB/FYN/PIK3CA/PIK3C2B/KLF4/RGL2/PTEN/KBTBD2/PIK3C2A/PTK2/NEDD4	23
GO:0060538	skeletal muscle organ development	25/988	166/18722	2.08289307685144e-06	5.29393685370088e-05	MEOX2/HLX/MEF2C/CAV1/CAV2/RCAN1/NOTCH1/IGF2/FLNB/VAMP5/DDX17/RB1/TGFB1/CFLAR/RHOA/SKI/NR2F2/EGR1/FOXN2/PPP3CA/PRKAA1/NR1D2/PLEC/MYL6/BTG2	25
GO:0010718	positive regulation of epithelial to mesenchymal transition	13/988	52/18722	2.11394883427891e-06	5.3472839084236e-05	LOXL2/WWTR1/ENG/JAG1/NOTCH1/TGFBR2/RGCC/MDK/TGFB1/FERMT2/SDCBP/SMAD2/SMAD4	13
GO:0046578	regulation of Ras protein signal transduction	27/988	189/18722	2.34436981198941e-06	5.90203433236387e-05	IGF1/HEG1/COL3A1/RASIP1/F2R/LPAR6/RASA4/DLC1/NOTCH1/ITGB1/NRP1/RGL2/RDX/OGT/MAP4K4/ARPP19/CYTH1/ABCA1/TNFAIP1/STARD13/PPP2CB/F11R/SHOC2/CRK/ARHGEF3/ARFGEF3/ARHGAP17	27
GO:0048015	phosphatidylinositol-mediated signaling	26/988	178/18722	2.3562660705091e-06	5.90400253138885e-05	EDN1/KDR/IGF1/TEK/SELP/PLCB4/PREX2/CEACAM1/F2R/FN1/FGFR1/PLCB1/ANGPT1/ZFP36L1/PDGFB/FYN/PIK3CA/PIK3C2B/KLF4/RGL2/PTEN/KBTBD2/OGT/PIK3C2A/PTK2/NEDD4	26
GO:0061045	negative regulation of wound healing	16/988	78/18722	2.51133490617713e-06	6.23374346804341e-05	CD34/EDN1/CD109/PROS1/CEACAM1/THBD/TFPI/THBS1/SH2B3/PHLDB2/PDGFB/SLC12A2/GJA1/PTEN/CD9/CRK	16
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	16/988	78/18722	2.51133490617713e-06	6.23374346804341e-05	KDR/MMRN2/MEOX2/RHOJ/THBS1/HDAC7/NOTCH1/NRP1/MAP3K3/AKT3/KLF4/RHOA/PIK3C2A/GATA2/STARD13/PLK2	16
GO:0007159	leukocyte cell-cell adhesion	42/988	371/18722	2.69258806607041e-06	6.65257107300745e-05	PECAM1/FCGR2B/JAM2/IGF1/SELP/LRRC32/NT5E/HLX/CEACAM1/CAV1/MSN/ETS1/HLA-E/HLA-A/TGFBR2/IGF2/ITGB1/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/PRKAR1A/FYN/PIK3CA/KLF4/TNFRSF14/NFAT5/RHOA/ZMIZ1/RC3H1/CD44/F11R/CBLB/WNK1/CD46/HES1/ROCK1/HSPH1/BCL10	42
GO:0060841	venous blood vessel development	7/988	14/18722	2.76185905388294e-06	6.79212745103064e-05	APLNR/ACVRL1/HEG1/FOXF1/ENG/BMPR2/NOTCH1	7
GO:0010596	negative regulation of endothelial cell migration	18/988	97/18722	2.7778791351203e-06	6.80004330219311e-05	MMRN2/ACVRL1/MEOX2/MEF2C/ANGPT2/THBS1/NOTCH1/VASH1/RGCC/TGFB1/KLF4/RHOA/PTPRM/NR2F2/STARD13/ATP2B4/SP100/SYNJ2BP	18
GO:0003094	glomerular filtration	9/988	25/18722	2.90365450660835e-06	7.07532694454291e-05	CD34/ADGRF5/MCAM/F2R/PDGFB/SULF2/GJA1/EMP2/GJA5	9
GO:0051495	positive regulation of cytoskeleton organization	30/988	226/18722	3.0981223570245e-06	7.51471505046309e-05	EDN1/TEK/ARHGEF15/CDC42EP5/PRKCE/PPM1F/ID1/RGCC/PXN/NRP1/GIT1/LIMCH1/NCKAP1/FLNA/ACTR2/RHOA/ABI2/FERMT2/CTTN/MYO1C/CCDC88A/GSN/ROCK2/DYNC1H1/WASL/CDC42/HSPA1A/DSTN/MTSS1/NIN	30
GO:0003281	ventricular septum development	15/988	71/18722	3.49583987286186e-06	8.44086427483736e-05	APLNR/HEG1/HOXA13/SMAD6/BMPR2/NOTCH1/TGFBR2/LUZP1/AP2B1/TBX3/HECTD1/GJA5/HES1/SMAD4/SAV1	15
GO:0048017	inositol lipid-mediated signaling	26/988	182/18722	3.58757613288413e-06	8.62316941985543e-05	EDN1/KDR/IGF1/TEK/SELP/PLCB4/PREX2/CEACAM1/F2R/FN1/FGFR1/PLCB1/ANGPT1/ZFP36L1/PDGFB/FYN/PIK3CA/PIK3C2B/KLF4/RGL2/PTEN/KBTBD2/OGT/PIK3C2A/PTK2/NEDD4	26
GO:0061564	axon development	49/988	467/18722	3.6230533660423e-06	8.66921598216969e-05	NFIB/ROBO4/LAMA2/NOVA2/SCARF1/EFNB2/PLXND1/FN1/BMPR2/MACF1/LAMB2/NOTCH1/ITGB1/SKIL/NRP1/KIF5B/APP/FEZ2/TTL/JAM3/EFNB1/DPYSL2/FYN/PLXNA2/KLF4/PTEN/PALLD/GDI1/FLNA/PTPRM/CREB1/NPTN/SEMA3F/VCL/RTN4/CTTN/CTNNA1/PICALM/RUFY3/PAK2/ZDHHC17/RAB11A/B4GALT5/EIF4G2/PTK2/SOS1/SMAD4/CAMSAP2/NIN	49
GO:0061299	retina vasculature morphogenesis in camera-type eye	6/988	10/18722	3.72021238039456e-06	8.86177944603403e-05	RHOJ/FZD4/ARHGEF15/COL4A1/NRP1/CLIC4	6
GO:0061448	connective tissue development	32/988	252/18722	3.84445095244728e-06	9.11684083008927e-05	MGP/CD34/EDN1/NFIB/ACVRL1/LOXL2/HYAL2/MEF2C/BMPR2/THRA/NOTCH1/SPTLC2/TGFBR2/SMAD5/SMAD1/TIMP1/PDGFB/SULF2/MDK/CHSY1/TGFB1/CFLAR/PIK3CA/SERPINH1/HIF1A/ACAT1/EGR1/CD44/EFEMP1/LTBP3/ATF2/ZMPSTE24	32
GO:0032233	positive regulation of actin filament bundle assembly	14/988	63/18722	3.9220886218787e-06	9.25961544863095e-05	ARHGEF15/PPM1F/ID1/RGCC/PXN/NRP1/LIMCH1/FLNA/RHOA/FERMT2/CCDC88A/ROCK2/CDC42/MTSS1	14
GO:0097581	lamellipodium organization	17/988	90/18722	4.059143254481e-06	9.54078272911641e-05	ABLIM1/S1PR1/FSCN1/ABLIM3/ENPP2/PARVB/ITGB1/NCKAP1/PIK3CA/ACTR2/ABI2/VCL/CTTN/CCDC88A/CD44/ARHGEF7/CDC42	17
GO:0060249	anatomical structure homeostasis	37/988	314/18722	4.15799590348121e-06	9.69736265263738e-05	PECAM1/CDH5/CD34/CLDN5/JAM2/ESAM/LDB2/ADGRF5/S1PR1/HOXA13/P2RY1/LAMA2/F2R/WWTR1/EPAS1/TJP1/ANGPT1/NOTCH1/ITGB1/B2M/PDK4/RB1/SLC12A2/LAMC1/JAM3/GJA1/TAOK1/AKT3/HIF1A/GATA2/VCL/SLC2A1/LIPA/F11R/PRKAA1/LTBP3/CLCN3	37
GO:0051607	defense response to virus	33/988	265/18722	4.18052719776724e-06	9.69736265263738e-05	IFI27/BST2/HYAL2/IFITM2/IFITM3/SEC14L1/IFI16/IFITM1/SERINC3/IFI44L/DDX17/DDX60/TSPAN6/PML/OAS2/LYST/CARD8/IFIT3/ZMYND11/MX1/ISG15/EIF2AK2/ADAR/HTRA1/PCBP2/PARP9/ZC3HAV1/IFIT2/PLSCR1/G3BP1/DTX3L/PUM2/ZMPSTE24	33
GO:0140546	defense response to symbiont	33/988	265/18722	4.18052719776724e-06	9.69736265263738e-05	IFI27/BST2/HYAL2/IFITM2/IFITM3/SEC14L1/IFI16/IFITM1/SERINC3/IFI44L/DDX17/DDX60/TSPAN6/PML/OAS2/LYST/CARD8/IFIT3/ZMYND11/MX1/ISG15/EIF2AK2/ADAR/HTRA1/PCBP2/PARP9/ZC3HAV1/IFIT2/PLSCR1/G3BP1/DTX3L/PUM2/ZMPSTE24	33
GO:0097205	renal filtration	9/988	26/18722	4.23339117051061e-06	9.77729299902277e-05	CD34/ADGRF5/MCAM/F2R/PDGFB/SULF2/GJA1/EMP2/GJA5	9
GO:0051051	negative regulation of transport	49/988	470/18722	4.33050972982696e-06	9.95829769906528e-05	FCGR2B/BST2/EDN1/CRHBP/STXBP6/P2RY1/CEACAM1/FOXF1/F2R/CAV1/CLIC2/SYT11/PRKCE/FABP5/THBS1/ANGPT1/PPM1F/NOTCH1/PKIG/PEA15/MDFIC/GNAI2/CTTNBP2NL/CALM1/GJA1/CD200/TBC1D4/SESTD1/PTEN/GDI1/CD36/DYSF/MAP4K4/SDCBP/TMBIM6/SLC30A1/PKD2/PLSCR1/PICALM/CRBN/TNFRSF1B/PPP3CA/SP100/PIM3/WNK1/MIDN/NEDD4/OAZ2/RAP1A	49
GO:0007346	regulation of mitotic cell cycle	48/988	457/18722	4.42132997675716e-06	0.000101233210502302	EDN1/IGF1/HOXA13/CAV2/PLCB1/TTC28/IGF2/RGCC/ZFP36L1/PDGFB/KMT2E/APP/RB1/TTL/DUSP1/PML/TGFB1/TAOK1/CDC25B/TMOD3/KLF4/PTEN/RDX/SDCBP/CYLD/PKN2/CTDSP2/PKD2/APC/IQGAP1/HECA/CCND1/PIM3/ZFP36L2/CDC27/CTDSP1/PHIP/WAC/ATF2/NEK7/HES1/RAB11A/CDC42/FOXN3/ID2/BTG2/PLK2/ZMPSTE24	48
GO:0003014	renal system process	19/988	110/18722	4.50160224818076e-06	0.000102628803185992	CD34/EDN1/ADGRF5/MCAM/F2R/NPR1/HYAL2/PCSK5/PDGFB/SULF2/GNAI2/PKN1/AKAP11/GJA1/RHOA/EMP2/GJA5/GSN/MAGED2	19
GO:0030900	forebrain development	42/988	379/18722	4.63102478369197e-06	0.000105128220730648	NFIB/COL3A1/NDNF/ETS1/PLCB1/DLC1/DIXDC1/SLC38A2/NOTCH1/B2M/NRP1/KIF5B/APP/CDK6/MDK/ATRX/FYN/PTEN/FLNA/RHOA/SUN1/HIF1A/SKI/TACC1/CREB1/GATA2/PCM1/CELF1/NR2F2/ZMIZ1/RTN4/SLC2A1/RAPGEF2/TBX3/ATP2B4/CRK/UBA6/HES1/BTBD3/ID2/BTG2/NIN	42
GO:0097191	extrinsic apoptotic signaling pathway	29/988	219/18722	4.72692444810047e-06	0.000106439448260003	IFI27/IGF1/TNFSF10/HYAL2/CAV1/FGFR1/THBS1/SKIL/NRP1/PEA15/PML/TGFB1/CFLAR/FYN/ZMYND11/PTEN/ITGA6/CYLD/RB1CC1/CTTN/FEM1B/HIPK1/CTNNA1/TNFRSF1B/SP100/PAK2/PHIP/HSPA1A/BCL10	29
GO:0043393	regulation of protein binding	27/988	196/18722	4.72886102962364e-06	0.000106439448260003	RAMP2/CLDN5/PLXND1/CAV1/FKBP1A/ADAM15/ANGPT1/ID1/MFNG/B2M/NRP1/PDGFB/CARD16/HIPK2/APP/TMBIM6/RALB/IFIT2/RAPGEF2/ADD1/PPP2CB/CBLB/CRK/DTX3L/ROCK1/CDC42/PLK2	27
GO:0030509	BMP signaling pathway	23/988	152/18722	4.86165222483364e-06	0.000108724334056477	CDH5/ACVRL1/HOXA13/SMAD6/ENG/BMPR2/NOTCH1/FSTL1/SKIL/SMAD5/SMAD1/SMURF2/CRIM1/HIPK2/XIAP/TGFB1/SKI/HTRA1/EGR1/SMAD2/HES1/SMAD4/CTDSPL2	23
GO:0019221	cytokine-mediated signaling pathway	49/988	472/18722	4.87130864183764e-06	0.000108724334056477	IFI27/EDN1/IL33/PLVAP/LEPR/CEACAM1/FZD4/LIFR/CAV1/IFITM2/IL1R1/PLCB1/IFITM3/ANGPT1/NOTCH1/OSMR/UGCG/SH2B3/IFITM1/TMSB4X/PDGFB/ACTN4/IL13RA1/CARD16/JAK1/IL6ST/LIMS1/OAS2/CARD8/PARP14/TNFRSF14/MX1/CSF2RB/ISG15/HIF1A/CYLD/STAT3/ADAR/IFNAR1/PARP9/EGR1/HIPK1/CD44/TNFRSF1B/SP100/WNK1/SOS1/HSPA1A/SMAD4	49
GO:0016358	dendrite development	31/988	243/18722	4.92628902044102e-06	0.000109491411199091	PREX2/SCARF1/MEF2C/ID1/ITGB1/MEF2A/NRP1/PDLIM5/APP/FYN/PTEN/ACTR2/RHOA/ABI2/ADAM10/RAPGEF2/IQGAP1/PICALM/PPP3CA/PAK2/CRK/DIP2A/UBA6/STRN/WASL/CDC42/EIF4G2/BTBD3/NEDD4/PLK2/CAMSAP2	31
GO:0001892	embryonic placenta development	16/988	82/18722	4.99758232195449e-06	0.000110613155392593	RSPO3/PCDH12/EPAS1/VASH1/IGF2/ZFP36L1/PDGFB/SOCS3/HIF1A/GATA2/NR2F2/PKD2/HECTD1/HES1/BPTF/MAPK1	16
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	12/988	48/18722	5.20644513858581e-06	0.000114757828116879	TNFSF10/HYAL2/CAV1/THBS1/SKIL/PEA15/PML/PTEN/CYLD/CTNNA1/PAK2/BCL10	12
GO:0001894	tissue homeostasis	33/988	268/18722	5.33459347373955e-06	0.000117096531126052	PECAM1/CDH5/CD34/CLDN5/JAM2/ESAM/LDB2/ADGRF5/S1PR1/HOXA13/LAMA2/F2R/WWTR1/EPAS1/TJP1/ANGPT1/NOTCH1/ITGB1/B2M/PDK4/RB1/SLC12A2/LAMC1/JAM3/GJA1/AKT3/GATA2/VCL/SLC2A1/LIPA/F11R/LTBP3/CLCN3	33
GO:0002683	negative regulation of immune system process	46/988	434/18722	5.48661122394949e-06	0.000119937772928476	A2M/FCGR2B/BST2/ADGRF5/COL3A1/LRRC32/HLX/CEACAM1/FOXF1/SYT11/PLCB1/HLA-E/HLA-A/AHR/THBS1/ANGPT1/HLA-B/SEC14L1/IFI16/TSPAN6/CDK6/MDK/YES1/PKN1/DUSP1/TGFB1/CD200/PRKAR1A/FYN/PARP14/TNFRSF14/CD59/ISG15/TMBIM6/GATA2/ADAR/LRCH1/HTRA1/PCBP2/RC3H1/CBLB/CRK/CD46/WASL/ID2/PLK2	46
GO:0050680	negative regulation of epithelial cell proliferation	24/988	164/18722	5.51610818783334e-06	0.000120088388089224	SPARC/NFIB/ACVRL1/CD109/LIMS2/CEACAM1/MEF2C/CAV1/CAV2/THBS1/VASH1/RGCC/B2M/RB1/CDK6/TGFB1/GJA1/PTEN/PTPRM/NR2F2/ATF2/SYNJ2BP/SAV1/MTSS1	24
GO:0045667	regulation of osteoblast differentiation	21/988	132/18722	5.58217533526332e-06	0.000121030675024158	IGF1/VEGFC/WWTR1/MEF2C/SMAD6/BMPR2/JAG1/ID3/HDAC7/NOTCH1/IFITM1/SMAD5/SMAD1/CRIM1/PDLIM7/CDK6/IL6ST/SKI/FERMT2/NBR1/PTK2	21
GO:0030010	establishment of cell polarity	22/988	143/18722	5.90268808574942e-06	0.000127459671184963	CDH5/FSCN1/TCF15/FOXF1/MSN/ITGB1/JAM3/GJA1/MYH9/RHOA/CYTH1/RUFY3/CRK/MYO9A/GSN/HES1/MAP4/ROCK2/ROCK1/CDC42/PTK2/AMOTL2	22
GO:0002685	regulation of leukocyte migration	28/988	210/18722	6.00553588334722e-06	0.000128726718293214	EDN1/JAM2/PLVAP/SELP/VEGFC/ITGA2/MTUS1/MSN/IL1R1/PLCB1/THBS1/CD81/APP/MDK/DUSP1/JAM3/CD200/TNFRSF14/RHOA/ADAM10/LRCH1/MOSPD2/CD9/CRK/WNK1/WASL/PTK2/MAPK1	28
GO:0048844	artery morphogenesis	15/988	74/18722	6.00983172754463e-06	0.000128726718293214	ACVRL1/ADGRF5/HOXA13/FOXF1/ENG/BMPR2/JAG1/NOTCH1/NRP1/MDK/AKT3/PKD2/ZMIZ1/GJA5/HES1	15
GO:0071634	regulation of transforming growth factor beta production	11/988	41/18722	6.12551401306687e-06	0.000129636376244666	CD34/LRRC32/FN1/THBS1/LTBP1/CD200/HIF1A/CREB1/CD46/ATF2/SMAD4	11
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	11/988	41/18722	6.12551401306687e-06	0.000129636376244666	LIMS2/NEDD9/NRP1/MDK/LIMS1/FLNA/FERMT2/ARHGEF7/CRK/CDC42/DOCK1	11
GO:1905314	semi-lunar valve development	11/988	41/18722	6.12551401306687e-06	0.000129636376244666	TIE1/SMAD6/BMPR2/JAG1/NOTCH1/RB1/TGFB1/TNFRSF1B/GJA5/ROCK2/ROCK1	11
GO:1900024	regulation of substrate adhesion-dependent cell spreading	13/988	57/18722	6.37649847952086e-06	0.000134412539377836	LIMS2/NEDD9/NRP1/ACTN4/MDK/LIMS1/FLNA/FERMT2/ARHGEF7/CRK/CDC42/PTK2/DOCK1	13
GO:0044319	wound healing, spreading of cells	10/988	34/18722	6.57466540062536e-06	0.000137498514205204	ACVRL1/CEACAM1/ITGA5/PHLDB2/PTEN/FLNA/RHOA/FERMT2/CD44/CD151	10
GO:0090505	epiboly involved in wound healing	10/988	34/18722	6.57466540062536e-06	0.000137498514205204	ACVRL1/CEACAM1/ITGA5/PHLDB2/PTEN/FLNA/RHOA/FERMT2/CD44/CD151	10
GO:0001890	placenta development	22/988	144/18722	6.62614403611392e-06	0.000137659127210513	HSD17B2/RSPO3/PCDH12/BMPR2/EPAS1/VASH1/IGF2/ZFP36L1/PDGFB/SOCS3/GJA1/HIF1A/GATA2/NR2F2/PKD2/HTRA1/HECTD1/ASH1L/HES1/BPTF/PTK2/MAPK1	22
GO:0051146	striated muscle cell differentiation	34/988	283/18722	6.63417480532594e-06	0.000137659127210513	EDN1/JAM2/IGF1/EHD2/SORBS2/EFNB2/MEF2C/TANC1/CAV2/PIEZO1/RCAN1/NOTCH1/IGF2/ITGB1/ATP11A/CD81/MEF2A/PDLIM5/RB1/TGFB1/CFLAR/PRKAR1A/MYH9/TMOD3/CAPN2/SKI/TBX3/SPAG9/CD9/PPP3CA/PLEC/SMAD4/MYOF/ZMPSTE24	34
GO:0071453	cellular response to oxygen levels	25/988	177/18722	6.73897787593358e-06	0.000139289690571826	CD34/EDN1/NDNF/CAV1/FOXO1/EPAS1/PRKCE/NOTCH1/RGCC/ZFP36L1/CARD16/HIPK2/GNB1/CFLAR/MALAT1/PTEN/ERO1A/EGLN1/HIF1A/NDRG1/TMBIM6/ATP6V1A/EGR1/PRKAA1/ROCK2	25
GO:0050920	regulation of chemotaxis	29/988	223/18722	6.76953562862084e-06	0.000139378966121062	EDN1/KDR/S1PR1/VEGFC/ADGRA2/NOVA2/ITGA2/EFNB2/BMPR2/MTUS1/FGFR1/ANGPT2/THBS1/PPM1F/NOTCH1/TMSB4X/NRP1/PDGFB/MDK/DUSP1/JAM3/TGFB1/STX3/ADAM10/SEMA3F/MOSPD2/WNK1/PTK2/MAPK1	29
GO:0031098	stress-activated protein kinase signaling cascade	31/988	247/18722	6.90412705028905e-06	0.000141499331305473	FCGR2B/MECOM/CDC42EP5/FOXO1/PLCB1/MAP4K2/ZFP36L1/SASH1/MDFIC/HIPK2/APP/MAP3K3/DUSP1/AIDA/TAOK1/MAP3K11/ZMYND11/RHOA/MAP4K4/ZFP36/SDCBP/CYLD/EIF2AK2/HIPK3/RB1CC1/PJA2/NBR1/ATF2/CDC42/MAPK1/ZMPSTE24	31
GO:0045445	myoblast differentiation	16/988	84/18722	6.92579558347574e-06	0.000141499331305473	IGF1/MEF2C/JAG1/EPAS1/ID3/PLCB1/NOTCH1/ZFP36L1/DDX17/LGALS1/RB1/MBNL1/TGFB1/IGFBP3/TBX3/PLEC	16
GO:0048738	cardiac muscle tissue development	30/988	236/18722	7.48670933928643e-06	0.000152009362716888	EDN1/IGF1/HEG1/S1PR1/SORBS2/EFNB2/MEF2C/ENG/FKBP1A/NOTCH1/TGFBR2/ITGB1/SMAD5/SMAD1/MEF2A/PDLIM5/TGFB1/GJA1/PRKAR1A/PTEN/CREB1/TBX3/GJA5/PLEC/CDC42/MAPK1/ID2/SMAD4/SAV1/ZMPSTE24	30
GO:1902414	protein localization to cell junction	17/988	94/18722	7.49744974243685e-06	0.000152009362716888	PECAM1/CDH5/HEG1/CGNL1/TJP1/KIF5B/JAK1/JAM3/STX3/FLNA/FERMT2/ADAM10/VCL/PAK2/F11R/RAB11A/RAP1A	17
GO:0043410	positive regulation of MAPK cascade	49/988	480/18722	7.72441398193079e-06	0.000156015540197781	FCGR2B/IGFBP4/EDN1/KDR/IGF1/TEK/KL/RAMP3/P2RY1/FZD4/F2R/FGFR1/CAV2/PLCB1/PRKCE/THBS1/ANGPT1/NOTCH1/MAP4K2/IGF2/CD81/NRP1/PDGFB/SASH1/HIPK2/APP/GNAI2/MAP3K3/SHC1/TGFB1/TAOK1/CFLAR/MAP3K11/PTEN/CD36/FERMT2/SDCBP/EIF2AK2/NPTN/RB1CC1/RAPGEF2/PJA2/IQGAP1/SPAG9/CD44/ROCK2/ROCK1/CDC42/RAP1A	49
GO:0032092	positive regulation of protein binding	16/988	85/18722	8.11922373065662e-06	0.000162752137574521	RAMP2/CLDN5/PLXND1/CAV1/FKBP1A/MFNG/B2M/NRP1/HIPK2/APP/RALB/RAPGEF2/ADD1/PPP2CB/DTX3L/PLK2	16
GO:0045069	regulation of viral genome replication	16/988	85/18722	8.11922373065662e-06	0.000162752137574521	BST2/IFITM2/IFITM3/NOTCH1/IFI16/IFITM1/PABPC1/OAS2/MX1/ISG15/EIF2AK2/ADAR/PKN2/ZC3HAV1/FAM111A/PLSCR1	16
GO:0009415	response to water	7/988	16/18722	8.38552333541828e-06	0.000166831085984052	COL18A1/PIK3CA/PKD2/ATP2B4/CD9/PLEC/ATF2	7
GO:2001044	regulation of integrin-mediated signaling pathway	7/988	16/18722	8.38552333541828e-06	0.000166831085984052	LIMS2/TIMP1/LIMS1/FLNA/PHACTR4/EMP2/CTNNA1	7
GO:0051894	positive regulation of focal adhesion assembly	9/988	28/18722	8.5046292936981e-06	0.000168569368687031	KDR/TEK/PPM1F/NRP1/LIMS1/FERMT2/MAP4K4/IQGAP1/ROCK1	9
GO:0016049	cell growth	49/988	482/18722	8.64744080102582e-06	0.000170762845855201	MEG3/IGFBP4/BST2/EDN1/IGF1/ACVRL1/NRN1/CEACAM1/NPR1/HYAL2/SORBS2/FN1/BMPR2/ADAM15/CCDC85B/MACF1/LAMB2/TGFBR2/ITGB1/IGFBP7/RPS6KA3/NRP1/PDLIM5/APP/RB1/TTL/PML/TGFB1/GJA1/ITSN2/DPYSL2/GDI1/RHOA/SDCBP/KIAA1109/ADAM10/SEMA3F/VCL/RTN4/CTTN/IQGAP1/RUFY3/SPAG9/RAB11A/CDC42/EIF4G2/HSPA1A/SMAD4/NIN	49
GO:0001569	branching involved in blood vessel morphogenesis	10/988	35/18722	8.77141571688207e-06	0.000171932694789954	EDN1/KDR/NOTCH4/COL4A1/PLXND1/ENG/TGFBR2/NRP1/MDK/PPP3R1	10
GO:0090504	epiboly	10/988	35/18722	8.77141571688207e-06	0.000171932694789954	ACVRL1/CEACAM1/ITGA5/PHLDB2/PTEN/FLNA/RHOA/FERMT2/CD44/CD151	10
GO:0030278	regulation of ossification	19/988	115/18722	8.80606142151536e-06	0.000171977199526065	MGP/KL/S1PR1/MEF2C/SMAD6/BMPR2/SRGN/NOTCH1/BCOR/MDK/CHSY1/TGFB1/ISG15/HIF1A/NBR1/LTBP3/NIPBL/MAPK1/ZMPSTE24	19
GO:0051701	biological process involved in interaction with host	27/988	203/18722	9.16876302093074e-06	0.000178404648964044	ITGA2/HYAL2/EFNB2/ITGA5/CAV1/IFITM2/CAV2/SCARB1/IFITM3/ITGB1/IFITM1/CD81/NRP1/LGALS1/SCARB2/PML/KPNA3/LAMP1/TNFRSF14/PLSCR1/THOC2/F11R/TRIM13/XPR1/GSN/CD46/HSPA1A	27
GO:0048010	vascular endothelial growth factor receptor signaling pathway	13/988	59/18722	9.55651228155018e-06	0.000185270778246696	KDR/MMRN2/CLEC14A/VEGFC/FZD4/HHEX/ITGA5/NRP1/FYN/HIF1A/PAK2/PTK2/NEDD4	13
GO:0010812	negative regulation of cell-substrate adhesion	14/988	68/18722	1.01059726545169e-05	0.000195210642693795	ACVRL1/FZD4/JAG1/ADAM15/ANGPT2/DLC1/THBS1/NOTCH1/PHLDB2/ACTN4/LGALS1/PTEN/RHOA/MAP4K4	14
GO:0018105	peptidyl-serine phosphorylation	36/988	315/18722	1.11074789998353e-05	0.000213778726257699	RAMP3/RPS6KA2/CAV1/PDE4D/PRKCE/ANGPT1/PPM1F/TGFBR2/FNIP2/RPS6KA3/PDGFB/HIPK2/APP/PKN1/PRKCH/TGFB1/AKT3/PIK3CA/PTEN/HIPK3/PKN2/ATP2B4/HIPK1/CSNK1A1/CD44/PAK2/PRKAA1/WNK1/ROCK2/MAST4/SMG1/DYRK1A/ROCK1/MAPK1/PLK2/CSNK1G3	36
GO:0014902	myotube differentiation	19/988	117/18722	1.13785481812795e-05	0.000218205227216451	JAM2/IGF1/EHD2/MEF2C/TANC1/CAV2/PIEZO1/RCAN1/NOTCH1/ATP11A/CD81/CFLAR/MYH9/CAPN2/SKI/CD9/PPP3CA/PLEC/MYOF	19
GO:0009615	response to virus	40/988	367/18722	1.15355681412151e-05	0.000220420640165952	IFI27/BST2/HYAL2/IFITM2/IFITM3/SEC14L1/IFI16/IFITM1/CLU/SERINC3/IFI44L/DDX17/DDX60/TSPAN6/CDK6/PML/OAS2/IFI44/LYST/CARD8/IFIT3/ZMYND11/MX1/ISG15/HIF1A/EIF2AK2/ADAR/IFNAR1/HTRA1/PCBP2/PARP9/ZC3HAV1/IFIT2/PLSCR1/G3BP1/XPR1/DTX3L/ATF2/PUM2/ZMPSTE24	40
GO:0050777	negative regulation of immune response	26/988	194/18722	1.1638401739365e-05	0.000221588494765257	A2M/FCGR2B/COL3A1/HLX/CEACAM1/FOXF1/HLA-E/HLA-A/AHR/HLA-B/SEC14L1/IFI16/TSPAN6/YES1/FYN/PARP14/TNFRSF14/CD59/ISG15/ADAR/HTRA1/PCBP2/RC3H1/CRK/CD46/PLK2	26
GO:0070302	regulation of stress-activated protein kinase signaling cascade	26/988	195/18722	1.27691542820124e-05	0.000242249098378749	FCGR2B/MECOM/FOXO1/PLCB1/MAP4K2/SASH1/MDFIC/HIPK2/APP/MAP3K3/DUSP1/AIDA/TAOK1/MAP3K11/ZMYND11/MAP4K4/SDCBP/CYLD/EIF2AK2/HIPK3/RB1CC1/PJA2/NBR1/CDC42/MAPK1/ZMPSTE24	26
GO:0050679	positive regulation of epithelial cell proliferation	27/988	207/18722	1.31645611246721e-05	0.000248861739125474	EGFL7/APLNR/KDR/IGF1/ACVRL1/TEK/VEGFC/BMPR2/FGFR1/CAV2/ID1/NOTCH1/IGF2/NRP1/PDGFB/MDK/LAMC1/CFLAR/AKT3/HIF1A/STAT3/GATA2/HTRA1/RTN4/CCND1/NRAS/CDC42	27
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	7/988	17/18722	1.36059242804689e-05	0.000255387525716787	HLA-E/HLA-A/HLA-B/HLA-C/B2M/ERAP1/TAPBP	7
GO:2000811	negative regulation of anoikis	7/988	17/18722	1.36059242804689e-05	0.000255387525716787	ITGA5/CAV1/NOTCH1/ITGB1/PDK4/PIK3CA/PTK2	7
GO:0007389	pattern specification process	45/988	436/18722	1.36705366959121e-05	0.000255696799044667	APLNR/EDN1/ACVRL1/MEOX2/LRP6/SOX18/TCF15/FOXF1/DCHS1/MEF2C/HHEX/SMAD6/ENG/BMPR2/PCSK5/TSHZ1/NOTCH1/TGFBR2/SMAD5/MFNG/PCGF2/SMAD1/NRP1/BCOR/HIPK2/CHSY1/AIDA/EFNB1/PLXNA2/MIB1/HIF1A/SKI/NR2F2/SEMA3F/PKD2/TBX3/HIPK1/APC/SMAD2/ETS2/HES1/BPTF/BTG2/SMAD4/BHLHE40	45
GO:0036303	lymph vessel morphogenesis	8/988	23/18722	1.40864225098535e-05	0.000261633134169027	ACVRL1/CLEC14A/TIE1/SOX18/VEGFC/BMPR2/VASH1/PTPN14	8
GO:2000810	regulation of bicellular tight junction assembly	8/988	23/18722	1.40864225098535e-05	0.000261633134169027	CLDN5/TJP1/PRKCH/GJA1/MYO1C/F11R/ROCK2/ROCK1	8
GO:0071456	cellular response to hypoxia	22/988	151/18722	1.43926280105606e-05	0.000266388989519505	CD34/EDN1/NDNF/EPAS1/PRKCE/NOTCH1/RGCC/ZFP36L1/CARD16/HIPK2/GNB1/CFLAR/MALAT1/PTEN/ERO1A/EGLN1/HIF1A/NDRG1/TMBIM6/EGR1/PRKAA1/ROCK2	22
GO:0003176	aortic valve development	10/988	37/18722	1.51147798823411e-05	0.000278783717829848	TIE1/SMAD6/BMPR2/JAG1/NOTCH1/RB1/TGFB1/TNFRSF1B/ROCK2/ROCK1	10
GO:0008217	regulation of blood pressure	25/988	186/18722	1.62007573030812e-05	0.000296904641780823	CD34/RAMP2/EDN1/ACVRL1/ECE1/VEGFC/F2R/NPR1/RPS6KA2/BMPR2/PRCP/PCSK5/PDE4D/PDGFB/ADRB1/ERAP1/GJA1/RHOA/LNPEP/NR2F2/EMP2/F11R/GJA5/WNK1/ID2	25
GO:0003197	endocardial cushion development	11/988	45/18722	1.62090260008356e-05	0.000296904641780823	APLNR/ACVRL1/FOXF1/DCHS1/ENG/BMPR2/JAG1/NOTCH1/TGFBR2/TBX3/SMAD4	11
GO:0010038	response to metal ion	40/988	373/18722	1.6882140663869e-05	0.00030807075127561	SPARC/EDN1/FABP4/CRHBP/S100A16/LOXL2/MEF2C/CAV1/RASA4/SYT11/PAM/TXNIP/THBS1/B2M/MEF2A/APP/SLC12A2/CALM1/DUSP1/PTEN/GDI1/HIF1A/NDRG1/CREB1/SLC30A1/PKD2/CLIC4/PLSCR1/ADD1/IQGAP1/PPP2CB/PPP3CA/CCND1/PRKAA1/WNK1/SEC31A/MAPK1/NEDD4/JUN/CPNE8	40
GO:0048771	tissue remodeling	24/988	175/18722	1.69346120806623e-05	0.00030807075127561	ACVRL1/RSPO3/TIE1/LEPR/S1PR1/CEACAM1/F2R/MEF2C/CAV1/BMPR2/JAG1/EPAS1/TIMP1/PDK4/MDK/TGFB1/GJA1/FLNA/HIF1A/LIPA/PPP3CA/LTBP3/ROCK2/ROCK1	24
GO:0035304	regulation of protein dephosphorylation	16/988	90/18722	1.72921948310503e-05	0.00031350218069126	CDH5/NUAK1/FKBP1A/ITGA1/DLC1/RCAN1/PPP2R5A/GNAI2/CALM1/TGFB1/ARPP19/HSP90B1/ROCK2/ROCK1/PPP1R12A/YWHAB	16
GO:0007009	plasma membrane organization	21/988	142/18722	1.77612423948905e-05	0.000320910610889994	SPTBN1/TIE1/PLSCR4/EHD2/CAV1/CAV2/SYT11/UGCG/CLU/MYH9/PTEN/DYSF/NDRG1/PLSCR1/CD9/PLEC/GSN/SH3GLB1/WASL/MYOF/MTSS1	21
GO:0071772	response to BMP	23/988	165/18722	1.931901738443e-05	0.000346698041709771	CDH5/ACVRL1/HOXA13/SMAD6/ENG/BMPR2/NOTCH1/FSTL1/SKIL/SMAD5/SMAD1/SMURF2/CRIM1/HIPK2/XIAP/TGFB1/SKI/HTRA1/EGR1/SMAD2/HES1/SMAD4/CTDSPL2	23
GO:0071773	cellular response to BMP stimulus	23/988	165/18722	1.931901738443e-05	0.000346698041709771	CDH5/ACVRL1/HOXA13/SMAD6/ENG/BMPR2/NOTCH1/FSTL1/SKIL/SMAD5/SMAD1/SMURF2/CRIM1/HIPK2/XIAP/TGFB1/SKI/HTRA1/EGR1/SMAD2/HES1/SMAD4/CTDSPL2	23
GO:0035264	multicellular organism growth	20/988	132/18722	1.94613167051209e-05	0.000348075805850513	IGF1/HEG1/WWTR1/KLF2/IGF2/ZFP36L1/APP/ADRB1/ATRX/PIK3CA/PLAC8/CREB1/STAT3/CELF1/CLIC4/PLEC/NIPBL/WDR11/SOS1/ZMPSTE24	20
GO:0001938	positive regulation of endothelial cell proliferation	18/988	111/18722	1.96043144140629e-05	0.000349456772374168	EGFL7/APLNR/KDR/ACVRL1/TEK/VEGFC/BMPR2/FGFR1/CAV2/IGF2/NRP1/PDGFB/MDK/AKT3/HIF1A/STAT3/GATA2/NRAS	18
GO:0030032	lamellipodium assembly	14/988	72/18722	2.01284299593375e-05	0.000357599397806022	ABLIM1/S1PR1/FSCN1/ABLIM3/PARVB/ITGB1/NCKAP1/PIK3CA/ACTR2/ABI2/VCL/CCDC88A/ARHGEF7/CDC42	14
GO:0097709	connective tissue replacement	7/988	18/18722	2.12506890149896e-05	0.000376278866825415	F2R/TIMP1/TGFB1/HIF1A/PPP3CA/ROCK2/ROCK1	7
GO:0016311	dephosphorylation	43/988	417/18722	2.15932819082644e-05	0.000381074795670101	CDH5/PTPRB/NUAK1/NT5E/ITGA2/MEF2C/PLPP1/FKBP1A/ITGA1/DLC1/RCAN1/PPP2R5A/PPM1F/GNAI2/CTTNBP2NL/CALM1/DUSP1/TGFB1/DUSP6/CDC25B/PLPP3/PPP2R2A/PTEN/MTMR6/PTPRM/ARPP19/HSP90B1/PTPRG/CTDSP2/PPP3R1/PTP4A2/PPP2CB/PPP3CA/PTPN14/CTDSP1/PTPRA/PPP2R5E/ROCK2/ROCK1/PTPN12/PPP1R12A/CTDSPL2/YWHAB	43
GO:0031334	positive regulation of protein-containing complex assembly	29/988	237/18722	2.19429745286455e-05	0.000385963843364785	CDH5/FSCN1/RASIP1/CDC42EP5/MSN/PIEZO1/PRKCE/FNIP2/CLU/GIT1/NCKAP1/TGFB1/SLF2/ISG15/ACTR2/CD36/RHOA/ABI2/FERMT2/CREB1/ABCA1/CTTN/MYO1C/CRBN/GSN/SH3GLB1/WASL/HSPA1A/NIN	29
GO:0018209	peptidyl-serine modification	37/988	338/18722	2.20964402289142e-05	0.000387380496686444	RAMP3/NDNF/RPS6KA2/CAV1/PDE4D/PRKCE/ANGPT1/PPM1F/TGFBR2/FNIP2/RPS6KA3/PDGFB/HIPK2/APP/PKN1/PRKCH/TGFB1/AKT3/PIK3CA/PTEN/HIPK3/PKN2/ATP2B4/HIPK1/CSNK1A1/CD44/PAK2/PRKAA1/WNK1/ROCK2/MAST4/SMG1/DYRK1A/ROCK1/MAPK1/PLK2/CSNK1G3	37
GO:0007409	axonogenesis	43/988	418/18722	2.28768993231992e-05	0.000399743714489586	NFIB/ROBO4/LAMA2/NOVA2/EFNB2/PLXND1/FN1/BMPR2/MACF1/LAMB2/NOTCH1/ITGB1/SKIL/NRP1/KIF5B/APP/FEZ2/TTL/EFNB1/DPYSL2/FYN/PLXNA2/PTEN/PALLD/GDI1/PTPRM/CREB1/NPTN/SEMA3F/VCL/RTN4/CTTN/PICALM/RUFY3/PAK2/ZDHHC17/RAB11A/B4GALT5/EIF4G2/PTK2/SOS1/SMAD4/NIN	43
GO:0048525	negative regulation of viral process	16/988	92/18722	2.30047125786027e-05	0.000400659125303401	BST2/IFITM2/IFITM3/IFI16/IFITM1/PML/OAS2/MX1/ISG15/ZFP36/EIF2AK2/ZC3HAV1/FAM111A/PLSCR1/TRIM13/GSN	16
GO:0098727	maintenance of cell number	20/988	134/18722	2.43650920770536e-05	0.000422965258540224	IGF1/LDB2/TCF15/LOXL2/JAG1/NOTCH1/KLF4/SKI/STAT3/GATA2/PCM1/TBX3/ZFP36L2/NIPBL/KLF10/HES1/DDX6/RIF1/CNOT2/SAV1	20
GO:0051403	stress-activated MAPK cascade	29/988	239/18722	2.57075998263393e-05	0.000444816841294836	FCGR2B/MECOM/CDC42EP5/FOXO1/PLCB1/MAP4K2/ZFP36L1/SASH1/MDFIC/HIPK2/APP/MAP3K3/DUSP1/AIDA/TAOK1/MAP3K11/ZMYND11/MAP4K4/ZFP36/SDCBP/CYLD/EIF2AK2/HIPK3/RB1CC1/PJA2/NBR1/ATF2/CDC42/MAPK1	29
GO:0045185	maintenance of protein location	16/988	93/18722	2.64437226579374e-05	0.000454047554897389	CAV1/SRGN/TMSB4X/LTBP1/PML/GJA1/TMSB10/FLNA/SUN1/PKD2/VPS13C/CCDC88A/SP100/GSN/ARL2BP/YWHAB	16
GO:0001886	endothelial cell morphogenesis	6/988	13/18722	2.64975041449907e-05	0.000454047554897389	COL15A1/HEG1/HOXA13/COL18A1/NOTCH4/CLIC4	6
GO:0007183	SMAD protein complex assembly	6/988	13/18722	2.64975041449907e-05	0.000454047554897389	SMAD6/FKBP1A/SMAD1/TGFB1/SMAD2/SMAD4	6
GO:0030111	regulation of Wnt signaling pathway	36/988	328/18722	2.68444683942018e-05	0.000458513878167202	IGFBP4/RSPO3/SOX7/TMEM88/FZD4/ADGRA2/NXN/WWTR1/HHEX/CAV1/MACF1/DIXDC1/NOTCH1/RBMS3/SULF2/SMURF2/MDFIC/APP/XIAP/CCNY/MDK/GNAQ/CTNND1/TGFB1/PLPP3/SKI/CYLD/EGR1/FZD6/CSNK1A1/APC/TBL1XR1/G3BP1/WNK1/RNF213/CSNK1G3	36
GO:0032872	regulation of stress-activated MAPK cascade	25/988	192/18722	2.80008869296621e-05	0.00047673304926399	FCGR2B/MECOM/FOXO1/PLCB1/MAP4K2/SASH1/MDFIC/HIPK2/APP/MAP3K3/DUSP1/AIDA/TAOK1/MAP3K11/ZMYND11/MAP4K4/SDCBP/CYLD/EIF2AK2/HIPK3/RB1CC1/PJA2/NBR1/CDC42/MAPK1	25
GO:0045071	negative regulation of viral genome replication	12/988	56/18722	2.82495750145968e-05	0.000478615929910793	BST2/IFITM2/IFITM3/IFI16/IFITM1/OAS2/MX1/ISG15/EIF2AK2/ZC3HAV1/FAM111A/PLSCR1	12
GO:0060070	canonical Wnt signaling pathway	34/988	303/18722	2.82916795918654e-05	0.000478615929910793	IGFBP4/RSPO3/LRP6/SOX7/TMEM88/FZD4/ADGRA2/WWTR1/HHEX/CAV1/DIXDC1/NOTCH1/RBMS3/SULF2/SMURF2/XIAP/CCNY/MDK/GNAQ/CTNND1/TGFB1/PLPP3/KLF4/PTEN/CYLD/EGR1/FZD6/CSNK1A1/APC/TBL1XR1/G3BP1/WNK1/CSNK1G3/RAB5A	34
GO:0009612	response to mechanical stimulus	27/988	216/18722	2.85083861760839e-05	0.000480750944023358	EDN1/COL3A1/P2RY1/ITGA2/ENG/ETS1/PIEZO1/ANGPT2/TXNIP/THBS1/SLC38A2/TGFBR2/MDK/GJA1/FYN/PIK3CA/RHOA/SUN1/PKD2/SLC2A1/F11R/PLEC/GSN/PTK2/BTG2/BCL10/JUN	27
GO:0008361	regulation of cell size	24/988	181/18722	2.97971668227941e-05	0.000500894146084437	EDN1/FN1/BMPR2/MSN/MACF1/TMEM123/NRP1/SLC12A2/TTL/DPYSL2/AKT3/PTEN/GDI1/RDX/RHOA/CREB1/SEMA3F/RB1CC1/RTN4/CTTN/RUFY3/RAB11A/CLCN3/EIF4G2	24
GO:0033157	regulation of intracellular protein transport	28/988	229/18722	3.06386084466247e-05	0.000513414157944702	IFI27/ABLIM3/HYAL2/ANGPT1/CD81/KIF5B/PKIG/STOM/MDFIC/TGFB1/FYN/GDI1/FLNA/CD36/PCM1/MYO1C/RUFY3/SP100/LEPROT/PTPN14/PRKAA1/NUCB1/SH3GLB1/CDC42/MAPK1/XPO1/OAZ2/CTDSPL2	28
GO:1903053	regulation of extracellular matrix organization	11/988	48/18722	3.12013318557132e-05	0.000521199606344493	TIE1/FSCN1/TCF15/ETS1/NOTCH1/RGCC/PHLDB2/RB1/TGFB1/CFLAR/TNFRSF1B	11
GO:0071675	regulation of mononuclear cell migration	18/988	115/18722	3.2060545317503e-05	0.000533132230966234	JAM2/MSN/PLCB1/THBS1/APP/MDK/DUSP1/CD200/TNFRSF14/RHOA/ADAM10/LRCH1/MOSPD2/CRK/WNK1/WASL/PTK2/MAPK1	18
GO:0002483	antigen processing and presentation of endogenous peptide antigen	7/988	19/18722	3.21163994557973e-05	0.000533132230966234	HLA-E/HLA-A/HLA-B/HLA-C/B2M/ERAP1/TAPBP	7
GO:0061138	morphogenesis of a branching epithelium	24/988	182/18722	3.26423729279668e-05	0.000540175342658441	EDN1/KDR/RSPO3/TIE1/HOXA13/NOTCH4/RASIP1/FOXF1/DCHS1/COL4A1/PLXND1/ENG/NOTCH1/TGFBR2/NRP1/MDK/SOCS3/PML/PKD2/CLIC4/TBX3/PPP3R1/FEM1B/SMAD4	24
GO:0003012	muscle system process	45/988	452/18722	3.34441026286962e-05	0.000551344294263317	EDN1/CALCRL/IGF1/P2RY1/ITGA2/F2R/SORBS2/CAV1/FOXO1/LMCD1/PDE4D/CLIC2/NOTCH1/DOCK4/SMAD5/UTRN/MEF2A/SULF2/PDLIM5/CALM1/IL6ST/GJA1/CFLAR/PIK3CA/TMOD3/TPM3/KLF4/PDE4B/FLNA/RHOA/CALD1/PIK3C2A/CTTN/TBX3/ATP2B4/TNFRSF1B/PPP3CA/TPM4/GJA5/GSN/ROCK2/ROCK1/MYL6/SMAD4/MYOF	45
GO:1903900	regulation of viral life cycle	21/988	148/18722	3.35248883748214e-05	0.000551344294263317	BST2/IFITM2/CAV2/IFITM3/NOTCH1/IFI16/IFITM1/LGALS1/PABPC1/PML/OAS2/MX1/ISG15/EIF2AK2/ADAR/PKN2/ZC3HAV1/FAM111A/PLSCR1/TRIM13/GSN	21
GO:0030193	regulation of blood coagulation	13/988	66/18722	3.42712806458245e-05	0.000560150900894215	CD34/EDN1/PROS1/CEACAM1/F2R/CAV1/THBD/TFPI/THBS1/SH2B3/PDGFB/CD36/CD9	13
GO:0072678	T cell migration	13/988	66/18722	3.42712806458245e-05	0.000560150900894215	S1PR1/MSN/APP/SLC12A2/CD200/TNFRSF14/RHOA/ADAM10/LRCH1/F11R/CRK/PLEC/WNK1	13
GO:0045862	positive regulation of proteolysis	39/988	372/18722	3.5683827460693e-05	0.000580484002248295	SOX7/CLEC3B/F2R/UACA/TNFSF10/FN1/CAV1/HIP1/DLC1/PPM1F/IFI16/CLU/RNF144B/APP/PML/CFLAR/FYN/MYH9/CARD8/TRIB2/ATXN3/PTEN/RNF19A/RHOA/OGT/STAT3/CSNK1A1/PICALM/HECTD1/TNFRSF1B/SOCS4/GSN/ROCK2/PTK2/HSPA1A/PIAS1/PLK2/BCL10/TMTC3	39
GO:0033674	positive regulation of kinase activity	46/988	467/18722	3.57338608311733e-05	0.000580484002248295	EDN1/KDR/IGF1/TIE1/TEK/VEGFC/FZD4/BMPR2/FGFR1/THBS1/ANGPT1/NEDD9/MAP4K2/TGFBR2/IGF2/RGCC/CLU/CD81/PDGFB/SASH1/CCNY/CALM1/TGFB1/TAOK1/CDC25B/PIK3CA/MAP3K11/RHOA/RANBP2/FERMT2/RALB/PKD2/EGR1/RAPGEF2/ATP2B4/EMP2/CCDC88A/IQGAP1/CCND1/PAK2/WNK1/CDC42/PTK2/BCL10/RAP1A/CCNT1	46
GO:0150117	positive regulation of cell-substrate junction organization	9/988	33/18722	3.74081013122736e-05	0.000605828762715845	KDR/TEK/PPM1F/NRP1/LIMS1/FERMT2/MAP4K4/IQGAP1/ROCK1	9
GO:0032103	positive regulation of response to external stimulus	43/988	427/18722	3.80063779487002e-05	0.000611787514131804	EDN1/KDR/FABP4/IL33/S1PR1/VEGFC/ITGA2/SCARF1/HYAL2/BMPR2/FGFR1/THBD/ETS1/HLA-E/THBS1/PPM1F/OSMR/IFI16/TMSB4X/MGST2/CD81/NRP1/PDGFB/SASH1/DDX60/APP/MDK/IL6ST/TGFB1/STX3/FYN/LAMP1/FLNA/ADAM10/PARP9/MOSPD2/PLSCR1/CLOCK/PAK2/WNK1/PUM2/PTK2/MAPK1	43
GO:0048568	embryonic organ development	43/988	427/18722	3.80063779487002e-05	0.000611787514131804	APLNR/EDN1/KDR/RSPO3/SOX18/HLX/FOXF1/PCDH12/MEF2C/ENG/PCSK5/EPAS1/ID3/TSHZ1/NOTCH1/VASH1/SH2B3/TGFBR2/IGF2/PCGF2/ZFP36L1/PDGFB/HIPK2/SOCS3/TGFB1/KMT2A/MIB1/HIF1A/PHACTR4/GATA2/NR2F2/PKD2/TBX3/FZD6/HIPK1/HECTD1/EFEMP1/SMAD2/NIPBL/HES1/BPTF/MAPK1/ID2	43
GO:0055001	muscle cell development	24/988	184/18722	3.90774490555144e-05	0.000625829004599187	RAMP2/EDN1/IGF1/SORBS2/ENG/CAV2/RCAN1/NOTCH1/ITGB1/MEF2A/ACTN4/PDLIM5/CFLAR/PRKAR1A/TMOD3/DYSF/SKI/TBX3/PPP3CA/PLEC/HES1/SMAD4/MYOF/ZMPSTE24	24
GO:0010639	negative regulation of organelle organization	37/988	347/18722	3.91143127874492e-05	0.000625829004599187	CDH5/SPTBN1/IGF1/CGNL1/S1PR1/KANK3/RPS6KA2/VAT1/DLC1/SPTAN1/TJP1/TMSB4X/ARHGAP28/CLU/PHLDB2/FEZ2/DUSP1/TAOK1/ATRX/PRKAR1A/TMSB10/TBC1D4/PIK3CA/TMOD3/RDX/ADD1/APC/ARHGEF7/PAK2/F11R/GSN/MAP4/DYRK1A/HSPA1A/XRN1/SMAD4/CAMSAP2	37
GO:0003073	regulation of systemic arterial blood pressure	16/988	96/18722	3.96464485789659e-05	0.000627732411357964	EDN1/ECE1/F2R/RPS6KA2/BMPR2/PRCP/PCSK5/PDE4D/PDGFB/ADRB1/GJA1/RHOA/NR2F2/EMP2/GJA5/WNK1	16
GO:0036294	cellular response to decreased oxygen levels	22/988	161/18722	3.96969549821761e-05	0.000627732411357964	CD34/EDN1/NDNF/EPAS1/PRKCE/NOTCH1/RGCC/ZFP36L1/CARD16/HIPK2/GNB1/CFLAR/MALAT1/PTEN/ERO1A/EGLN1/HIF1A/NDRG1/TMBIM6/EGR1/PRKAA1/ROCK2	22
GO:0001763	morphogenesis of a branching structure	25/988	196/18722	3.97059657786664e-05	0.000627732411357964	EDN1/KDR/RSPO3/TIE1/HOXA13/NOTCH4/RASIP1/FOXF1/DCHS1/COL4A1/PLXND1/ENG/NOTCH1/TGFBR2/NRP1/MDK/SOCS3/PML/PKD2/RTN4/CLIC4/TBX3/PPP3R1/FEM1B/SMAD4	25
GO:0071674	mononuclear cell migration	25/988	196/18722	3.97059657786664e-05	0.000627732411357964	PECAM1/JAM2/S1PR1/MSN/PLCB1/THBS1/PDGFB/APP/MDK/SLC12A2/DUSP1/CD200/TNFRSF14/RHOA/ADAM10/LRCH1/MOSPD2/F11R/CRK/PLEC/WNK1/WASL/CDC42/PTK2/MAPK1	25
GO:0035904	aorta development	12/988	58/18722	4.09320854187092e-05	0.000645196551169683	APLNR/ACVRL1/PLXND1/SMAD6/ENG/JAG1/NOTCH1/AP2B1/PKD2/HECTD1/HES1/ADAMTS6	12
GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	6/988	14/18722	4.42992379633215e-05	0.000696205775328886	RAMP3/CAV1/PDE4D/GNAI2/PDE4B/ATP2B4	6
GO:0070167	regulation of biomineral tissue development	16/988	97/18722	4.5188163558799e-05	0.000708081194172095	MGP/KL/S1PR1/MEF2C/BMPR2/SRGN/NOTCH1/BCOR/TGFB1/ISG15/HIF1A/NBR1/LTBP3/ROCK2/ROCK1/ZMPSTE24	16
GO:0022612	gland morphogenesis	18/988	118/18722	4.55921628343679e-05	0.000711298988269393	NFIB/HOXA13/LIMS2/CEACAM1/PLXND1/CAV1/MSN/NOTCH1/TGFBR2/NRP1/SULF2/MDK/PML/TGFB1/CFLAR/TBX3/FEM1B/CDC42	18
GO:0061014	positive regulation of mRNA catabolic process	15/988	87/18722	4.5661324359914e-05	0.000711298988269393	ZFP36L1/PABPC1/ZFP36/TNRC6B/CELF1/CNOT6L/ZC3HAV1/RC3H1/ZFP36L2/CNOT8/ROCK2/TNRC6A/ROCK1/CNOT2/BTG2	15
GO:0031333	negative regulation of protein-containing complex assembly	20/988	140/18722	4.63856205586503e-05	0.000720469053823247	CDH5/SPTBN1/KANK3/SMAD6/THRA/SPTAN1/TMSB4X/CLU/JAM3/AIDA/TMSB10/TMOD3/CARD8/RDX/ADD1/CRBN/ARHGEF7/GSN/DYRK1A/CDC42	20
GO:1900046	regulation of hemostasis	13/988	68/18722	4.767448278503e-05	0.000738329016192651	CD34/EDN1/PROS1/CEACAM1/F2R/CAV1/THBD/TFPI/THBS1/SH2B3/PDGFB/CD36/CD9	13
GO:0002832	negative regulation of response to biotic stimulus	17/988	108/18722	4.89610253123727e-05	0.00075292682598765	A2M/CEACAM1/HLA-E/HLA-A/AHR/HLA-B/SEC14L1/IFI16/CARD16/TSPAN6/CARD8/PARP14/ISG15/ADAR/HTRA1/PCBP2/CRK	17
GO:0042110	T cell activation	47/988	487/18722	4.90155725066205e-05	0.00075292682598765	FCGR2B/IGF1/LEPR/LRRC32/HLX/CEACAM1/CAV1/FOXP1/FKBP1A/MSN/HLA-E/HLA-A/TGFBR2/IGF2/B2M/CD81/ZFP36L1/LGALS1/MDK/YES1/EFNB1/IL6ST/PRKAR1A/FYN/MYH9/PIK3CA/TNFRSF14/RAB27A/RHOA/STAT3/ZMIZ1/EGR1/RC3H1/CD44/TNFRSF1B/PPP3CA/ZFP36L2/CBLB/CD151/GSN/CD46/ATF2/HES1/SOS2/SOS1/HSPH1/BCL10	47
GO:0050767	regulation of neurogenesis	38/988	364/18722	4.9042297024045e-05	0.00075292682598765	VEGFC/PLXND1/FN1/BMPR2/MACF1/ID1/NOTCH1/SKIL/B2M/NRP1/MDK/DICER1/PRKCH/IL6ST/TGFB1/PLXNA2/PTEN/GDI1/ACTR2/HIF1A/SKI/PCM1/NPTN/SEMA3F/RTN4/SPEN/RAPGEF2/CTNNA1/RUFY3/TNFRSF1B/PPP3CA/CTDSP1/HES1/RAB11A/EIF4G2/ID2/BHLHE40/NIN	38
GO:1905475	regulation of protein localization to membrane	23/988	175/18722	4.98566243136406e-05	0.000763223021193254	SPTBN1/RAMP3/PRKCE/PPP2R5A/ITGB1/CD81/KIF5B/STOM/PRKCH/TGFB1/STX3/FYN/AP2B1/ACSL3/GDI1/ADAM10/MYO1C/ATP2B4/PICALM/HECTD1/GSN/RAB11A/RAP1A	23
GO:0033002	muscle cell proliferation	29/988	248/18722	5.09895887357613e-05	0.000778323837253919	EDN1/CALCRL/IGF1/S1PR1/ITGA2/NPR1/MEF2C/BMPR2/FOXP1/THBS1/ANGPT1/NOTCH1/TGFBR2/SMAD1/PDGFB/GNAI2/TGFB1/GJA1/CFLAR/PRKAR1A/IGFBP3/KLF4/PTEN/RHOA/STAT3/MAPK1/ID2/JUN/SAV1	29
GO:0043537	negative regulation of blood vessel endothelial cell migration	14/988	78/18722	5.13549281744943e-05	0.000780449818996942	MMRN2/ACVRL1/MEOX2/MEF2C/ANGPT2/THBS1/NOTCH1/VASH1/RGCC/TGFB1/KLF4/RHOA/STARD13/ATP2B4	14
GO:0050921	positive regulation of chemotaxis	20/988	141/18722	5.14227102125244e-05	0.000780449818996942	EDN1/KDR/S1PR1/VEGFC/ITGA2/BMPR2/FGFR1/THBS1/PPM1F/TMSB4X/NRP1/PDGFB/MDK/TGFB1/STX3/ADAM10/MOSPD2/WNK1/PTK2/MAPK1	20
GO:0050779	RNA destabilization	15/988	88/18722	5.23980447582381e-05	0.000792986933777096	ZFP36L1/PABPC1/ZFP36/TNRC6B/CELF1/CNOT6L/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/ROCK2/TNRC6A/ROCK1/CNOT2/BTG2	15
GO:0003171	atrioventricular valve development	8/988	27/18722	5.28117387792294e-05	0.000796977148850189	APLNR/DCHS1/SMAD6/BMPR2/NOTCH1/TGFBR2/GJA5/SMAD4	8
GO:0007568	aging	36/988	339/18722	5.39126757544288e-05	0.000811286497471744	EDN1/KL/NUAK1/P2RY1/LOXL2/HYAL2/COL4A2/VASH1/TGFBR2/B2M/CANX/TIMP1/APP/CDK6/SLC12A2/MAP3K3/PML/LIMS1/BAZ2B/AKT3/PTEN/ERO1A/CREB1/STAT3/ZMIZ1/TBX3/CTNNA1/PICALM/TNFRSF1B/PPP3CA/KAT6A/MAPK1/ID2/PLK2/JUN/ZMPSTE24	36
GO:0045787	positive regulation of cell cycle	34/988	313/18722	5.48297334493022e-05	0.000822755774244896	EDN1/IGF1/LRP6/HOXA13/PKP4/PLCB1/PRKCE/IGF2/RGCC/PDGFB/KMT2E/APP/RB1/CCNY/TTL/CDC25B/ATRX/TMOD3/SLF2/RDX/RHOA/PKN2/PKD2/PLSCR1/TBX3/CCND1/CDC27/PHIP/HES1/RAB11A/ROCK2/DYNC1H1/CDC42/CCNT1	34
GO:0010611	regulation of cardiac muscle hypertrophy	13/988	69/18722	5.59399045805905e-05	0.000837050065160836	EDN1/IGF1/FOXO1/LMCD1/NOTCH1/MEF2A/IL6ST/ATP2B4/TNFRSF1B/PPP3CA/ROCK2/ROCK1/SMAD4	13
GO:0019827	stem cell population maintenance	19/988	131/18722	5.77041520585984e-05	0.000858611920827101	LDB2/TCF15/LOXL2/JAG1/NOTCH1/KLF4/SKI/STAT3/GATA2/PCM1/TBX3/ZFP36L2/NIPBL/KLF10/HES1/DDX6/RIF1/CNOT2/SAV1	19
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	19/988	131/18722	5.77041520585984e-05	0.000858611920827101	CD109/SMAD6/ENG/CAV1/CAV2/FKBP1A/THBS1/SKIL/LTBP1/SMURF2/HIPK2/TGFB1/CFLAR/SKI/SDCBP/HTRA1/SMAD2/HSPA1A/SMAD4	19
GO:0110149	regulation of biomineralization	16/988	99/18722	5.8354828426103e-05	0.00086586829217726	MGP/KL/S1PR1/MEF2C/BMPR2/SRGN/NOTCH1/BCOR/TGFB1/ISG15/HIF1A/NBR1/LTBP3/ROCK2/ROCK1/ZMPSTE24	16
GO:0042063	gliogenesis	33/988	301/18722	5.85517265403092e-05	0.000866369836719004	VIM/NFIB/LEPR/P2RY1/LAMA2/ADGRG6/LAMB2/NOTCH1/CLU/APP/CDK6/MDK/DICER1/PRKCH/IL6ST/TGFB1/PTEN/RHOA/SUN1/SKI/NDRG1/CREB1/STAT3/ZMIZ1/RTN4/PPP3R1/CD9/TNFRSF1B/PLEC/HES1/B4GALT5/MAPK1/ID2	33
GO:0002698	negative regulation of immune effector process	17/988	110/18722	6.21395856300515e-05	0.000916182529200399	A2M/FCGR2B/BST2/HLX/CEACAM1/FOXF1/HLA-E/HLA-A/AHR/ANGPT1/HLA-B/TGFB1/CD59/TMBIM6/RC3H1/CRK/CD46	17
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	9/988	35/18722	6.22631575755542e-05	0.000916182529200399	KDR/RHOJ/HDAC7/NRP1/MAP3K3/AKT3/PIK3C2A/GATA2/PLK2	9
GO:0035265	organ growth	23/988	178/18722	6.51331794890848e-05	0.000955766434933752	EDN1/IGF1/HEG1/LEPR/S1PR1/HLX/SORBS2/MEF2C/NOTCH1/TGFBR2/IGF2/SMAD1/PDLIM5/GJA1/DUSP6/PRKAR1A/PTEN/WWC2/WWC3/SMAD2/MAPK1/SAV1/ZMPSTE24	23
GO:0045123	cellular extravasation	13/988	70/18722	6.5422423011502e-05	0.00095736614610771	PECAM1/JAM2/PLVAP/SELP/ITGA1/IL1R1/PLCB1/ITGB1/MDK/JAM3/F11R/CRK/ROCK1	13
GO:0044403	biological process involved in symbiotic interaction	32/988	290/18722	6.65863119435258e-05	0.000971721123747278	IFI27/ITGA2/HYAL2/EFNB2/FN1/ITGA5/CAV1/IFITM2/CAV2/SCARB1/IFITM3/ITGB1/IFITM1/CD81/NRP1/STOM/LGALS1/SCARB2/PML/KPNA3/LAMP1/TNFRSF14/PLSCR1/THOC2/F11R/TRIM13/XPR1/GSN/CD46/HSPA1A/JUN/CCNT1	32
GO:0071498	cellular response to fluid shear stress	7/988	21/18722	6.75331953675977e-05	0.000982839270664874	MEF2C/TFPI2/KLF2/KLF4/PKD2/PLEC/MTSS1	7
GO:0051496	positive regulation of stress fiber assembly	11/988	52/18722	6.8738336971422e-05	0.000997644934404901	ARHGEF15/PPM1F/RGCC/PXN/NRP1/LIMCH1/RHOA/FERMT2/CCDC88A/ROCK2/CDC42	11
GO:0090288	negative regulation of cellular response to growth factor stimulus	17/988	111/18722	6.98321346797518e-05	0.00101075830904316	MMRN2/ADGRA2/HHEX/SMAD6/THBS1/NOTCH1/SKIL/SULF2/SMURF2/CRIM1/HIPK2/CFLAR/SKI/HTRA1/ATP2B4/NEDD4/CTDSPL2	17
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	8/988	28/18722	7.05345825734421e-05	0.00101268638855576	HLA-E/HLA-A/HLA-B/HLA-C/B2M/ERAP1/LNPEP/TAPBP	8
GO:0010763	positive regulation of fibroblast migration	6/988	15/18722	7.05372672751565e-05	0.00101268638855576	PRKCE/THBS1/ITGB1/TGFB1/ARHGEF7/PTK2	6
GO:0090594	inflammatory response to wounding	6/988	15/18722	7.05372672751565e-05	0.00101268638855576	F2R/TIMP1/GIT1/MDK/TGFB1/HIF1A	6
GO:0050818	regulation of coagulation	13/988	71/18722	7.62686052469522e-05	0.00109201841259248	CD34/EDN1/PROS1/CEACAM1/F2R/CAV1/THBD/TFPI/THBS1/SH2B3/PDGFB/CD36/CD9	13
GO:0045860	positive regulation of protein kinase activity	39/988	386/18722	8.00776211683196e-05	0.00114040837438636	EDN1/IGF1/VEGFC/FZD4/BMPR2/FGFR1/THBS1/ANGPT1/NEDD9/MAP4K2/TGFBR2/IGF2/RGCC/CLU/PDGFB/SASH1/CCNY/CALM1/TGFB1/TAOK1/CDC25B/PIK3CA/MAP3K11/RHOA/FERMT2/RALB/PKD2/EGR1/RAPGEF2/ATP2B4/EMP2/CCDC88A/IQGAP1/CCND1/PAK2/WNK1/PTK2/RAP1A/CCNT1	39
GO:0050727	regulation of inflammatory response	39/988	386/18722	8.00776211683196e-05	0.00114040837438636	CDH5/FCGR2B/CALCRL/FABP4/IGF1/IL33/TEK/NT5E/FOXF1/ITGA2/HYAL2/FOXP1/SYT11/IL1R1/ETS1/HLA-E/OSMR/TMSB4X/MGST2/CD81/GIT1/APP/RB1/XIAP/MDK/YES1/SOCS3/IL6ST/CD200/FYN/KLF4/ZFP36/CYLD/CELF1/ASH1L/CLOCK/TNFRSF1B/NR1D2/PLK2	39
GO:1902946	protein localization to early endosome	5/988	10/18722	8.17199463158128e-05	0.00116068544072085	MSN/NRP1/RDX/DTX3L/ROCK2	5
GO:0043620	regulation of DNA-templated transcription in response to stress	11/988	53/18722	8.26499509080189e-05	0.00117076410459572	EPAS1/KLF2/NOTCH1/RPS6KA3/HIF1A/TMBIM6/EGR1/ATF6/HSPA1A/NEDD4/JUN	11
GO:0021543	pallium development	22/988	169/18722	8.32922904265192e-05	0.00117672512432359	COL3A1/PLCB1/DIXDC1/SLC38A2/KIF5B/CDK6/MDK/PTEN/FLNA/RHOA/SUN1/HIF1A/TACC1/CELF1/ZMIZ1/RTN4/SLC2A1/ATP2B4/CRK/UBA6/BTBD3/BTG2	22
GO:0007565	female pregnancy	24/988	193/18722	8.44772729021085e-05	0.00118715151760847	RAMP2/CRHBP/IDO1/ITGA2/BMPR2/PCSK5/THBD/ETS1/ANGPT2/PAM/SLC38A2/TGFBR2/IGFBP7/TIMP1/SMURF2/GJA1/CAPN2/LNPEP/NR2F2/SLC2A1/EMP2/ASH1L/MAPK1/MAGED2	24
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	24/988	193/18722	8.44772729021085e-05	0.00118715151760847	PECAM1/IGF1/ENPP2/ITGA5/ANGPT1/NEDD9/IGF2/CD81/NRP1/PDGFB/YES1/IL6ST/TGFB1/FYN/PARP14/TNFRSF14/CD36/PARP9/EHD4/IQGAP1/CD44/PAK2/HES1/ARL2BP	24
GO:0031623	receptor internalization	17/988	113/18722	8.77718059503569e-05	0.00123019481057598	RAMP2/CALCRL/RAMP3/CEACAM1/CAV1/ANGPT1/ITGB1/CD81/AP2B1/CD36/SDCBP/MKLN1/PPP3R1/PICALM/CD9/NEDD4/RAB5A	17
GO:0014743	regulation of muscle hypertrophy	13/988	72/18722	8.86384743781213e-05	0.0012390725681489	EDN1/IGF1/FOXO1/LMCD1/NOTCH1/MEF2A/IL6ST/ATP2B4/TNFRSF1B/PPP3CA/ROCK2/ROCK1/SMAD4	13
GO:0060395	SMAD protein signal transduction	14/988	82/18722	9.06464888799654e-05	0.00126381666385926	VIM/SPTBN1/WWTR1/SMAD6/BMPR2/SMAD5/SMAD1/HIPK2/TGFB1/SKI/ZMIZ1/SMAD2/SMAD4/JUN	14
GO:0045732	positive regulation of protein catabolic process	27/988	231/18722	9.20650158427958e-05	0.00128023393758359	CAV1/FOXO1/MSN/HACE1/CLU/RNF144B/CD81/SMURF2/GJA1/TRIB2/ATXN3/PTEN/RNF19A/RDX/CSNK1A1/APC/HECTD1/TNFRSF1B/SOCS4/CBLB/PTK2/HSPA1A/PIAS1/NEDD4/PLK2/OAZ2/TMTC3	27
GO:1903531	negative regulation of secretion by cell	20/988	147/18722	9.32209579894416e-05	0.00129292357399455	FCGR2B/EDN1/CRHBP/STXBP6/P2RY1/CEACAM1/FOXF1/F2R/SYT11/NOTCH1/GNAI2/GJA1/CD200/MAP4K4/SLC30A1/TNFRSF1B/PPP3CA/PIM3/MIDN/RAP1A	20
GO:0035089	establishment of apical/basal cell polarity	7/988	22/18722	9.45540381327924e-05	0.00130799752750363	FSCN1/TCF15/FOXF1/MSN/RHOA/MYO9A/CDC42	7
GO:0072073	kidney epithelium development	19/988	136/18722	9.66644301359015e-05	0.00133371805943353	PECAM1/CD34/PODXL/DCHS1/WWTR1/MEF2C/SMAD6/JAG1/LAMB2/NOTCH1/SMAD5/SMAD1/PKD2/ACAT1/IQGAP1/SMAD2/HES1/SMAD4/MTSS1	19
GO:0032271	regulation of protein polymerization	27/988	232/18722	9.90791977033482e-05	0.00136349403678805	CDH5/SPTBN1/ESAM/KANK3/CDC42EP5/PRKCE/SPTAN1/TMSB4X/ARHGAP28/GIT1/NCKAP1/TMSB10/TMOD3/RDX/ACTR2/RHOA/ABI2/CTTN/MYO1C/ADD1/ARHGEF7/GSN/WASL/DYRK1A/HSPA1A/CAMSAP2/NIN	27
GO:0003161	cardiac conduction system development	9/988	37/18722	9.97454422524287e-05	0.00136911573448295	NOTCH1/SMAD5/SMAD1/GJA1/TBX3/GJA5/CDC42/ID2/SMAD4	9
GO:1903037	regulation of leukocyte cell-cell adhesion	35/988	336/18722	0.000100298253729881	0.00137315547374518	FCGR2B/IGF1/SELP/LRRC32/HLX/CEACAM1/CAV1/ETS1/HLA-E/HLA-A/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/PRKAR1A/FYN/PIK3CA/KLF4/TNFRSF14/NFAT5/RHOA/ZMIZ1/RC3H1/CD44/CBLB/WNK1/CD46/HES1/HSPH1/BCL10	35
GO:0002237	response to molecule of bacterial origin	37/988	363/18722	0.000100943985859859	0.00137844332361843	SPARC/VIM/FCGR2B/EDN1/SELP/PLSCR4/F2R/MEF2C/SMAD6/THBD/TFPI/SCARB1/FOXP1/PRKCE/NOTCH1/MGST2/MTDH/RPS6KA3/B2M/GIT1/SASH1/CARD16/TGFB1/GJA1/CARD8/PDE4B/CAPN2/CSF2RB/CD36/RHOA/ZFP36/IFNAR1/ABCA1/TNFRSF1B/MAPK1/BCL10/JUN	37
GO:0070663	regulation of leukocyte proliferation	28/988	245/18722	0.000101907915964221	0.00138803807590242	FCGR2B/BST2/IGF1/IL33/LRRC32/MEF2C/HHEX/HLA-E/HLA-A/AHR/TGFBR2/IGF2/CD81/PKN1/EFNB1/IL6ST/PRKAR1A/TNFRSF14/RC3H1/TNFRSF1B/CBLB/CD320/CD46/HES1/SOS2/PTK2/SOS1/MAPK1	28
GO:0032386	regulation of intracellular transport	35/988	337/18722	0.000106400381054128	0.00144552128941056	IFI27/ABLIM3/EHD2/HYAL2/MSN/ANGPT1/CD81/KIF5B/PKIG/STOM/MDFIC/TGFB1/FYN/LAMP1/GDI1/FLNA/RDX/CD36/PCM1/MYO1C/RUFY3/SP100/LEPROT/PTPN14/PRKAA1/NUCB1/SH3GLB1/DYNC1H1/CDC42/MAPK1/XPO1/NEDD4/PPP1R12A/OAZ2/CTDSPL2	35
GO:0060419	heart growth	16/988	104/18722	0.000107020970549044	0.00145024335601153	EDN1/IGF1/HEG1/S1PR1/SORBS2/MEF2C/NOTCH1/TGFBR2/SMAD1/PDLIM5/GJA1/DUSP6/PRKAR1A/PTEN/MAPK1/SAV1	16
GO:0007219	Notch signaling pathway	22/988	172/18722	0.000108368988205402	0.00146477370317327	EGFL7/NOTCH4/SORBS2/JAG1/TSPAN14/NOTCH1/TGFBR2/MFNG/APP/IL6ST/MIB1/SEL1L/STAT3/ADAM10/GATA2/ZMIZ1/SPEN/MAML2/CD46/DTX3L/HES1/SYNJ2BP	22
GO:0032507	maintenance of protein location in cell	12/988	64/18722	0.000112610317665691	0.00151823859756383	CAV1/SRGN/TMSB4X/PML/GJA1/TMSB10/SUN1/VPS13C/CCDC88A/SP100/GSN/ARL2BP	12
GO:0048588	developmental cell growth	27/988	234/18722	0.000114559491270862	0.0015406076395717	EDN1/IGF1/NRN1/SORBS2/FN1/BMPR2/MACF1/LAMB2/TGFBR2/ITGB1/NRP1/PDLIM5/APP/TTL/ITSN2/DPYSL2/GDI1/SEMA3F/VCL/RTN4/CTTN/IQGAP1/RUFY3/SPAG9/RAB11A/EIF4G2/NIN	27
GO:0000910	cytokinesis	22/988	173/18722	0.00011810530200245	0.00158428122282074	SPTBN1/PKP4/PRKCE/RHOB/GIT1/CALM1/CDC25B/MYH9/ACTR2/RHOA/PKN2/SON/APC/KLHL9/PLEC/PDCD6IP/SH3GLB1/RAB11A/ROCK2/ROCK1/CDC42/PLK2	22
GO:0061157	mRNA destabilization	14/988	84/18722	0.000118630659113868	0.00158732005343291	ZFP36L1/PABPC1/ZFP36/TNRC6B/CELF1/CNOT6L/RC3H1/ZFP36L2/CNOT8/ROCK2/TNRC6A/ROCK1/CNOT2/BTG2	14
GO:0061384	heart trabecula morphogenesis	8/988	30/18722	0.000120895129809311	0.00160951110162171	HEG1/TEK/S1PR1/ENG/ADGRG6/FKBP1A/NOTCH1/SOS1	8
GO:0070168	negative regulation of biomineral tissue development	8/988	30/18722	0.000120895129809311	0.00160951110162171	SRGN/NOTCH1/BCOR/TGFB1/HIF1A/LTBP3/ROCK2/ROCK1	8
GO:0008286	insulin receptor signaling pathway	17/988	116/18722	0.000122269006016683	0.00162373239990155	KL/GRB14/FOXO1/CAV2/IGF2/PIK3R3/PDK4/GNAI2/SOCS3/SHC1/PIK3CA/OGT/PIK3C2A/APC/PRKAA1/PTPRA/PHIP	17
GO:0030279	negative regulation of ossification	9/988	38/18722	0.000124633993037815	0.00165101189779768	MEF2C/SMAD6/SRGN/NOTCH1/BCOR/MDK/CHSY1/HIF1A/LTBP3	9
GO:0031099	regeneration	24/988	198/18722	0.000126341726555521	0.0016694707747834	IGF1/NNMT/SCARF1/ADAM15/ANGPT2/LAMB2/NOTCH1/TGFBR2/CD81/SULF2/MDK/JAM3/CPT1A/CFLAR/KLF4/PTEN/FLNA/MAP4K4/CTNNA1/CD9/PPP3CA/CCND1/PTPN12/RAP1A	24
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	23/988	186/18722	0.000128217750270885	0.00168269585917244	BST2/F2R/TNFSF10/FKBP1A/PRKCE/MTDH/CARD16/LGALS1/TSPAN6/MAP3K3/GJA1/CFLAR/FYN/FLNA/CD36/RHOA/SLC44A2/S100A13/TRIM13/ZDHHC17/REL/PLK2/BCL10	23
GO:1902115	regulation of organelle assembly	23/988	186/18722	0.000128217750270885	0.00168269585917244	FSCN1/MSN/FEZ2/RDX/RHOA/SDCBP/CYLD/RALB/CNOT6L/CCDC88A/G3BP1/PRKAA1/GSN/PDCD6IP/MAP4/SH3GLB1/DYNC1H1/CNOT2/HSPA1A/PLK2/SMAD4/RAB5A/SENP6	23
GO:0001659	temperature homeostasis	22/988	174/18722	0.000128609660923194	0.00168269585917244	FABP4/LAMA4/LEPR/NOVA2/CAV1/FOXO1/EPAS1/THRA/FABP5/ID1/NOTCH1/RB1/ADRB1/GJA1/CD36/PLAC8/OGT/STAT3/LNPEP/EGR1/APC/DYNC1H1	22
GO:0048639	positive regulation of developmental growth	22/988	174/18722	0.000128609660923194	0.00168269585917244	EDN1/IGF1/HLX/MEF2C/FN1/BMPR2/AGRN/PLCB1/MACF1/NOTCH1/TGFBR2/IGF2/NRP1/ITSN2/GDI1/CREB1/CELF1/RUFY3/NIPBL/RAB11A/EIF4G2/MAPK1	22
GO:0006929	substrate-dependent cell migration	7/988	23/18722	0.000129758619967828	0.0016894063462478	VEGFC/ITGA2/FN1/NRP1/ANKS1A/SDCBP/CTTN	7
GO:2000737	negative regulation of stem cell differentiation	7/988	23/18722	0.000129758619967828	0.0016894063462478	TCF15/JAG1/NOTCH1/N4BP2L2/STAT3/ZFP36L2/HES1	7
GO:0090068	positive regulation of cell cycle process	27/988	236/18722	0.000132167615313688	0.00171656325805944	EDN1/IGF1/HOXA13/PKP4/PLCB1/PRKCE/IGF2/RGCC/PDGFB/KMT2E/APP/RB1/CDC25B/ATRX/TMOD3/SLF2/RDX/RHOA/PKN2/PLSCR1/CCND1/CDC27/PHIP/RAB11A/ROCK2/DYNC1H1/CDC42	27
GO:0030100	regulation of endocytosis	25/988	211/18722	0.000132996231079579	0.00171891965813802	BICD1/ITGA2/CAV1/HIP1/SYT11/ANGPT1/CLU/B2M/CALM1/AP2B1/MIB1/CD36/SDCBP/MKLN1/GATA2/EHD4/PPP3R1/PICALM/PPP3CA/CD151/WASL/ROCK1/CDC42/HNRNPK/RAB5A	25
GO:0043491	protein kinase B signaling	25/988	211/18722	0.000132996231079579	0.00171891965813802	KDR/IGF1/TEK/RAMP3/HYAL2/ENG/FGFR1/HIP1/THBS1/ANGPT1/SH2B3/IGF2/ITGB1/MTDH/ZFP36L1/PIK3R3/TGFB1/PIK3CA/KLF4/PTEN/SETX/RRAS/FERMT2/RTN4/PTK2	25
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	18/988	128/18722	0.00013425651597772	0.00172680535804758	CD109/SMAD6/ENG/CAV1/CAV2/FKBP1A/THBS1/SKIL/LTBP1/SMURF2/HIPK2/TGFB1/SKI/SDCBP/HTRA1/SMAD2/HSPA1A/SMAD4	18
GO:0035303	regulation of dephosphorylation	18/988	128/18722	0.00013425651597772	0.00172680535804758	CDH5/NUAK1/ITGA2/MEF2C/FKBP1A/ITGA1/DLC1/RCAN1/PPP2R5A/GNAI2/CALM1/TGFB1/ARPP19/HSP90B1/ROCK2/ROCK1/PPP1R12A/YWHAB	18
GO:0048754	branching morphogenesis of an epithelial tube	20/988	151/18722	0.00013567316542653	0.00174081124334717	EDN1/KDR/TIE1/NOTCH4/RASIP1/FOXF1/DCHS1/COL4A1/PLXND1/ENG/NOTCH1/TGFBR2/NRP1/MDK/PML/PKD2/CLIC4/TBX3/PPP3R1/SMAD4	20
GO:0035850	epithelial cell differentiation involved in kidney development	10/988	47/18722	0.000138996718115151	0.00177062486001842	CD34/PODXL/WWTR1/MEF2C/JAG1/LAMB2/NOTCH1/PDGFB/IQGAP1/MTSS1	10
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	10/988	47/18722	0.000138996718115151	0.00177062486001842	EPAS1/KLF2/NOTCH1/HIF1A/TMBIM6/EGR1/ATF6/HSPA1A/NEDD4/JUN	10
GO:0045646	regulation of erythrocyte differentiation	10/988	47/18722	0.000138996718115151	0.00177062486001842	ETS1/B2M/ZFP36L1/CDK6/ISG15/HIF1A/ZFP36/STAT3/GATA2/HSPA1A	10
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	11/988	56/18722	0.000139688086540691	0.00177517491795251	ZFP36L1/PABPC1/ZFP36/TNRC6B/CNOT6L/RC3H1/ZFP36L2/CNOT8/TNRC6A/CNOT2/BTG2	11
GO:0003093	regulation of glomerular filtration	5/988	11/18722	0.000143305082544838	0.00181246809161472	F2R/PDGFB/GJA1/EMP2/GJA5	5
GO:0003174	mitral valve development	5/988	11/18722	0.000143305082544838	0.00181246809161472	DCHS1/SMAD6/BMPR2/NOTCH1/GJA5	5
GO:0055017	cardiac muscle tissue growth	15/988	96/18722	0.000145730706764343	0.0018344111714033	EDN1/IGF1/HEG1/S1PR1/SORBS2/MEF2C/NOTCH1/TGFBR2/SMAD1/PDLIM5/GJA1/PRKAR1A/PTEN/MAPK1/SAV1	15
GO:1904035	regulation of epithelial cell apoptotic process	15/988	96/18722	0.000145730706764343	0.0018344111714033	CDH5/RAMP2/KDR/TEK/NDNF/THBS1/ANGPT1/RGCC/ZFP36L1/MDK/CFLAR/ZFP36/GATA2/GSN/TIA1	15
GO:0071902	positive regulation of protein serine/threonine kinase activity	24/988	200/18722	0.000147693041577476	0.00185471734482163	EDN1/FZD4/BMPR2/FGFR1/THBS1/MAP4K2/IGF2/RGCC/PDGFB/SASH1/CCNY/CALM1/TGFB1/TAOK1/MAP3K11/RHOA/FERMT2/RALB/PKD2/RAPGEF2/ATP2B4/IQGAP1/CCND1/CCNT1	24
GO:0010001	glial cell differentiation	26/988	225/18722	0.000148535231931232	0.00185651565180872	VIM/NFIB/LAMA2/ADGRG6/LAMB2/NOTCH1/CLU/APP/CDK6/MDK/DICER1/IL6ST/TGFB1/PTEN/RHOA/SKI/NDRG1/STAT3/PPP3R1/CD9/TNFRSF1B/PLEC/HES1/B4GALT5/MAPK1/ID2	26
GO:0050769	positive regulation of neurogenesis	26/988	225/18722	0.000148535231931232	0.00185651565180872	VEGFC/PLXND1/FN1/BMPR2/MACF1/NOTCH1/SKIL/NRP1/MDK/DICER1/PRKCH/IL6ST/TGFB1/PLXNA2/GDI1/ACTR2/HIF1A/NPTN/SPEN/RUFY3/TNFRSF1B/HES1/RAB11A/EIF4G2/ID2/NIN	26
GO:0032496	response to lipopolysaccharide	35/988	343/18722	0.000150583475189031	0.00187769816949327	SPARC/VIM/EDN1/SELP/PLSCR4/F2R/MEF2C/SMAD6/THBD/TFPI/SCARB1/FOXP1/PRKCE/NOTCH1/MGST2/MTDH/RPS6KA3/GIT1/SASH1/CARD16/TGFB1/GJA1/CARD8/PDE4B/CAPN2/CSF2RB/CD36/RHOA/ZFP36/IFNAR1/ABCA1/TNFRSF1B/MAPK1/BCL10/JUN	35
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	40/988	412/18722	0.000154121733124449	0.00190281721981704	IFI27/WWTR1/CAV1/HACE1/CLU/RNF144B/CANX/SMURF2/DNAJC10/PML/TRIB2/ATXN3/SEL1L/RNF19A/OGT/RYBP/SDCBP/HSP90B1/EDEM3/PCBP2/SPOP/TNFAIP1/MAN1A1/FEM1B/CSNK1A1/TBL1XR1/PPP2CB/HECTD1/CRBN/CLOCK/SOCS4/CDC27/TRIM13/WAC/APPBP2/HSPA1A/XPO1/PIAS1/NEDD4/PLK2	40
GO:0051651	maintenance of location in cell	25/988	213/18722	0.000154520232980173	0.00190281721981704	APLNR/F2R/CAV1/PDE4D/ITPR1/CLIC2/FKBP1A/SRGN/PRKCE/TMSB4X/CALM1/PML/GJA1/TMSB10/ERO1A/ITPR2/SUN1/HSP90B1/PKD2/VPS13C/SLC30A7/CCDC88A/SP100/GSN/ARL2BP	25
GO:0051090	regulation of DNA-binding transcription factor activity	42/988	440/18722	0.000154629596831602	0.00190281721981704	EDN1/LRP6/FZD4/CAV1/ID3/ID1/TMSB4X/RGCC/CLU/MTDH/CARD16/HIPK2/APP/RB1/PRKCH/CD200/CFLAR/PLPP3/TAX1BP1/CARD8/KLF4/PTEN/EGLN1/FLNA/CD36/PURA/CYLD/STAT3/EIF2AK2/PKD2/FZD6/CLOCK/PPP3CA/SP100/TRIM13/ATF2/HES1/HSPA1A/ID2/BCL10/SAV1/BHLHE40	42
GO:0070371	ERK1 and ERK2 cascade	34/988	330/18722	0.000154786495653773	0.00190281721981704	KDR/IGF1/TEK/RAMP3/P2RY1/CEACAM1/F2R/FN1/ANGPT1/NOTCH1/ZFP36L1/NRP1/PDGFB/APP/GNAI2/DUSP1/SHC1/TGFB1/DUSP6/CFLAR/KLF4/PTEN/RRAS/CD36/FERMT2/NPTN/RAPGEF2/CD44/ZFP36L2/ZDHHC17/SYNJ2BP/MAPK1/SMAD4/RAP1A	34
GO:0060055	angiogenesis involved in wound healing	8/988	31/18722	0.000155463605685353	0.00190281721981704	CD34/KDR/MCAM/NDNF/PRCP/ETS1/SLC12A2/GATA2	8
GO:0071711	basement membrane organization	8/988	31/18722	0.000155463605685353	0.00190281721981704	RAMP2/COL4A1/CAV1/CAV2/NID1/LAMB2/ITGB1/PHLDB2	8
GO:0090162	establishment of epithelial cell polarity	8/988	31/18722	0.000155463605685353	0.00190281721981704	TCF15/FOXF1/MSN/RHOA/CYTH1/MYO9A/HES1/CDC42	8
GO:0110150	negative regulation of biomineralization	8/988	31/18722	0.000155463605685353	0.00190281721981704	SRGN/NOTCH1/BCOR/TGFB1/HIF1A/LTBP3/ROCK2/ROCK1	8
GO:0045198	establishment of epithelial cell apical/basal polarity	6/988	17/18722	0.000159222344198198	0.00194356569776395	TCF15/FOXF1/MSN/RHOA/MYO9A/CDC42	6
GO:0009952	anterior/posterior pattern specification	24/988	201/18722	0.000159524594168878	0.00194356569776395	MEOX2/LRP6/TCF15/FOXF1/HHEX/BMPR2/PCSK5/TSHZ1/NOTCH1/PCGF2/HIPK2/PLXNA2/MIB1/SKI/NR2F2/TBX3/HIPK1/SMAD2/ETS2/HES1/BPTF/BTG2/SMAD4/BHLHE40	24
GO:1903039	positive regulation of leukocyte cell-cell adhesion	27/988	239/18722	0.00016312257471225	0.0019828538143512	IGF1/SELP/HLX/CAV1/ETS1/HLA-E/HLA-A/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/FYN/PIK3CA/TNFRSF14/NFAT5/RHOA/ZMIZ1/CD44/CD46/HES1/HSPH1/BCL10	27
GO:0061005	cell differentiation involved in kidney development	11/988	57/18722	0.000164941621372955	0.00200038788295236	CD34/PODXL/WWTR1/MEF2C/JAG1/LAMB2/NOTCH1/PDGFB/IQGAP1/HES1/MTSS1	11
GO:0030522	intracellular receptor signaling pathway	29/988	265/18722	0.000165860418543054	0.00200694884578747	PLPP1/PRCP/FOXP1/THRA/FABP5/KLF2/AHR/SEC14L1/ACTN4/DDX17/DDX60/TSPAN6/XIAP/PKN1/PML/RHOA/CYLD/STAT3/NR2F2/ZMIZ1/CLOCK/CTBP2/NR1D2/NR3C1/PUM2/CNOT2/HSPA1A/NEDD4/ARID1A	29
GO:0070661	leukocyte proliferation	33/988	318/18722	0.000168130148971119	0.00202978943485133	FCGR2B/BST2/IGF1/IL33/LRRC32/MEF2C/HHEX/MSN/HLA-E/HLA-A/AHR/TGFBR2/IGF2/CLU/CD81/PKN1/EFNB1/IL6ST/PRKAR1A/FYN/TNFRSF14/PURA/RC3H1/TNFRSF1B/CBLB/CD320/CD151/CD46/HES1/SOS2/PTK2/SOS1/MAPK1	33
GO:0061162	establishment of monopolar cell polarity	7/988	24/18722	0.000174889564252117	0.00210184019300282	FSCN1/TCF15/FOXF1/MSN/RHOA/MYO9A/CDC42	7
GO:2000209	regulation of anoikis	7/988	24/18722	0.000174889564252117	0.00210184019300282	ITGA5/CAV1/NOTCH1/ITGB1/PDK4/PIK3CA/PTK2	7
GO:0060828	regulation of canonical Wnt signaling pathway	28/988	253/18722	0.00017659231882817	0.00210864989191175	IGFBP4/RSPO3/SOX7/TMEM88/FZD4/ADGRA2/WWTR1/HHEX/CAV1/NOTCH1/RBMS3/SULF2/SMURF2/XIAP/CCNY/MDK/GNAQ/CTNND1/TGFB1/CYLD/EGR1/FZD6/CSNK1A1/APC/TBL1XR1/G3BP1/WNK1/CSNK1G3	28
GO:0097305	response to alcohol	28/988	253/18722	0.00017659231882817	0.00210864989191175	SPARC/CLDN5/CRHBP/LRP6/ADAM15/PRKCE/KLF2/AHR/TGFBR2/IGFBP7/CALM1/CPT1A/TGFB1/GNB1/FYN/TP53INP1/KLF4/PTEN/ITPR2/ACTR2/RHOA/STAT3/ABCA1/CTNNA1/CCND1/PRKAA1/SMAD2/XRN1	28
GO:0051216	cartilage development	23/988	190/18722	0.00017664706361083	0.00210864989191175	MGP/EDN1/NFIB/ACVRL1/LOXL2/HYAL2/MEF2C/BMPR2/THRA/TGFBR2/SMAD5/SMAD1/TIMP1/SULF2/MDK/CHSY1/TGFB1/SERPINH1/HIF1A/CD44/EFEMP1/LTBP3/ZMPSTE24	23
GO:1902117	positive regulation of organelle assembly	12/988	67/18722	0.000177771185680483	0.0021173106240689	FSCN1/MSN/RHOA/SDCBP/RALB/CNOT6L/CCDC88A/G3BP1/PDCD6IP/SH3GLB1/DYNC1H1/CNOT2	12
GO:0006109	regulation of carbohydrate metabolic process	22/988	178/18722	0.000179381201892485	0.00213170681085655	IGFBP4/IGF1/NNMT/LEPR/P2RY1/ZBTB20/PRKCE/IGF2/PDGFB/GIT1/PDK4/APP/SCARB2/TGFB1/RANBP2/HIF1A/OGT/ARPP19/STAT3/PRKAA1/MIDN/ZMPSTE24	22
GO:0043112	receptor metabolic process	21/988	166/18722	0.000179954540808711	0.00213374669816043	RAMP2/CALCRL/RAMP3/ECE1/CEACAM1/CAV1/ANGPT1/ITGB1/CD81/TGFB1/AP2B1/CD36/SDCBP/MKLN1/PPP3R1/PICALM/CD9/DTX3L/SH3GLB1/NEDD4/RAB5A	21
GO:0071901	negative regulation of protein serine/threonine kinase activity	17/988	120/18722	0.000186409594477233	0.00220536250749012	LRP6/HEG1/RASIP1/HYAL2/HHEX/CAV1/SH2B3/PKIG/RB1/DUSP1/AIDA/PRKAR1A/PTEN/HIPK3/NR2F2/APC/PRKAR2A	17
GO:0034340	response to type I interferon	11/988	58/18722	0.000193965129787777	0.00228965059873927	IFI27/IFITM2/IFITM3/IFITM1/JAK1/OAS2/MX1/ISG15/ADAR/IFNAR1/SP100	11
GO:0003180	aortic valve morphogenesis	8/988	32/18722	0.00019777343074255	0.00231403626454719	TIE1/SMAD6/JAG1/NOTCH1/RB1/TGFB1/ROCK2/ROCK1	8
GO:0035456	response to interferon-beta	8/988	32/18722	0.00019777343074255	0.00231403626454719	BST2/IFITM2/IFITM3/IFI16/IFITM1/XAF1/CAPN2/PLSCR1	8
GO:0051497	negative regulation of stress fiber assembly	8/988	32/18722	0.00019777343074255	0.00231403626454719	CGNL1/S1PR1/DLC1/TJP1/ARHGAP28/PHLDB2/PAK2/F11R	8
GO:0060317	cardiac epithelial to mesenchymal transition	8/988	32/18722	0.00019777343074255	0.00231403626454719	ENG/JAG1/ADAM15/NOTCH1/TGFBR2/RTN4/TBX3/SMAD4	8
GO:0030195	negative regulation of blood coagulation	10/988	49/18722	0.000200448911538151	0.00232485724473943	CD34/EDN1/PROS1/CEACAM1/THBD/TFPI/THBS1/SH2B3/PDGFB/CD9	10
GO:0030857	negative regulation of epithelial cell differentiation	10/988	49/18722	0.000200448911538151	0.00232485724473943	ACVRL1/ZEB1/NOTCH4/CAV1/JAG1/ID1/NOTCH1/TBX3/CCND1/HES1	10
GO:0035088	establishment or maintenance of apical/basal cell polarity	10/988	49/18722	0.000200448911538151	0.00232485724473943	FSCN1/TCF15/FOXF1/MSN/RHOA/CLIC4/MYO9A/PDCD6IP/CDC42/SYNJ2BP	10
GO:0061245	establishment or maintenance of bipolar cell polarity	10/988	49/18722	0.000200448911538151	0.00232485724473943	FSCN1/TCF15/FOXF1/MSN/RHOA/CLIC4/MYO9A/PDCD6IP/CDC42/SYNJ2BP	10
GO:0006909	phagocytosis	32/988	308/18722	0.000205241422090096	0.00236854492979758	PECAM1/CD93/FCGR2B/LEPR/ITGA2/SCARB1/SYT11/PRKCE/THBS1/ITGB1/ELMO1/YES1/FYN/LYST/MYH9/PIK3CA/PTEN/CD36/RAB27A/DYSF/KIAA1109/GATA2/ABCA1/PLSCR1/CD302/GSN/CLCN3/CDC42/PTK2/DOCK1/RAB5A/RAP1A	32
GO:0060411	cardiac septum morphogenesis	12/988	68/18722	0.000205649050586652	0.00236854492979758	APLNR/SMAD6/ENG/BMPR2/JAG1/NOTCH1/TGFBR2/NRP1/TBX3/HES1/SMAD4/SAV1	12
GO:0030500	regulation of bone mineralization	13/988	78/18722	0.000205712025581256	0.00236854492979758	MGP/KL/S1PR1/MEF2C/BMPR2/SRGN/BCOR/TGFB1/ISG15/HIF1A/NBR1/LTBP3/ZMPSTE24	13
GO:0038127	ERBB signaling pathway	17/988	121/18722	0.000206424678512709	0.00236854492979758	CEACAM1/HIP1/ITGA1/SHC1/TGFB1/PIK3CA/PIK3C2A/RTN4/CCDC88A/IQGAP1/SOCS4/EFEMP1/CBLB/PTK2/SOS1/MAPK1/PTPN12	17
GO:0003300	cardiac muscle hypertrophy	15/988	99/18722	0.000207018765307587	0.00236854492979758	EDN1/IGF1/SORBS2/FOXO1/LMCD1/NOTCH1/MEF2A/PDLIM5/IL6ST/ATP2B4/TNFRSF1B/PPP3CA/ROCK2/ROCK1/SMAD4	15
GO:0010717	regulation of epithelial to mesenchymal transition	15/988	99/18722	0.000207018765307587	0.00236854492979758	LOXL2/WWTR1/ENG/JAG1/NOTCH1/TGFBR2/RGCC/PHLDB2/MDK/TGFB1/PTEN/FERMT2/SDCBP/SMAD2/SMAD4	15
GO:0106106	cold-induced thermogenesis	19/988	144/18722	0.000207782744217936	0.00236854492979758	FABP4/LAMA4/LEPR/NOVA2/CAV1/EPAS1/THRA/FABP5/ID1/NOTCH1/RB1/ADRB1/GJA1/CD36/PLAC8/OGT/LNPEP/APC/DYNC1H1	19
GO:0120161	regulation of cold-induced thermogenesis	19/988	144/18722	0.000207782744217936	0.00236854492979758	FABP4/LAMA4/LEPR/NOVA2/CAV1/EPAS1/THRA/FABP5/ID1/NOTCH1/RB1/ADRB1/GJA1/CD36/PLAC8/OGT/LNPEP/APC/DYNC1H1	19
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	28/988	256/18722	0.000215270777588549	0.00244864747441194	CDH5/ACVRL1/HOXA13/CD109/SMAD6/ENG/CAV1/BMPR2/CAV2/FKBP1A/THBS1/NOTCH1/FSTL1/SKIL/LTBP1/SMURF2/CRIM1/HIPK2/XIAP/TGFB1/SKI/SDCBP/HTRA1/SMAD2/HES1/HSPA1A/SMAD4/CTDSPL2	28
GO:0042176	regulation of protein catabolic process	38/988	391/18722	0.000218469751198413	0.00247972503924352	CAV1/FOXO1/MSN/HACE1/CLU/RNF144B/CD81/TIMP1/SMURF2/HIPK2/PML/GJA1/FYN/TRIB2/ATXN3/PTEN/FLNA/RNF19A/RDX/OGT/RYBP/SDCBP/CSNK1A1/APC/HECTD1/TNFRSF1B/SOCS4/CBLB/WAC/ROCK1/PTK2/HSPA1A/XPO1/PIAS1/NEDD4/PLK2/OAZ2/TMTC3	38
GO:0046328	regulation of JNK cascade	18/988	133/18722	0.000219455004009781	0.00248559697505321	FCGR2B/MECOM/PLCB1/MAP4K2/MDFIC/HIPK2/APP/AIDA/TAOK1/MAP3K11/ZMYND11/MAP4K4/SDCBP/CYLD/HIPK3/RB1CC1/PJA2/CDC42	18
GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6/988	18/18722	0.000228208171789801	0.00257923789052644	ZFP36L1/PABPC1/ZFP36/TNRC6B/RC3H1/ZFP36L2	6
GO:0045807	positive regulation of endocytosis	15/988	100/18722	0.000231882881652886	0.00260441931533591	BICD1/ITGA2/HIP1/ANGPT1/CLU/B2M/AP2B1/MIB1/CD36/GATA2/PPP3CA/CD151/WASL/CDC42/HNRNPK	15
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	7/988	25/18722	0.000231907066294029	0.00260441931533591	F2R/PCSK5/PDGFB/GJA1/RHOA/EMP2/GJA5	7
GO:0061339	establishment or maintenance of monopolar cell polarity	7/988	25/18722	0.000231907066294029	0.00260441931533591	FSCN1/TCF15/FOXF1/MSN/RHOA/MYO9A/CDC42	7
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	16/988	111/18722	0.000232950163066959	0.00261061448567867	KDR/IGF1/TEK/SELP/CEACAM1/F2R/FN1/FGFR1/ANGPT1/PDGFB/FYN/KLF4/RGL2/PTEN/PTK2/NEDD4	16
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	13/988	79/18722	0.000234525716721667	0.00261699492124091	KDR/IGF1/TEK/SELP/F2R/FN1/FGFR1/ANGPT1/PDGFB/FYN/RGL2/PTK2/NEDD4	13
GO:0034333	adherens junction assembly	5/988	12/18722	0.000234997473161128	0.00261699492124091	RAMP2/JAM3/VCL/HIPK1/PAK2	5
GO:0045602	negative regulation of endothelial cell differentiation	5/988	12/18722	0.000234997473161128	0.00261699492124091	ACVRL1/ZEB1/NOTCH4/JAG1/ID1	5
GO:0060337	type I interferon signaling pathway	10/988	50/18722	0.000238855304432571	0.00264885047420839	IFI27/IFITM2/IFITM3/IFITM1/JAK1/OAS2/ISG15/ADAR/IFNAR1/SP100	10
GO:1900047	negative regulation of hemostasis	10/988	50/18722	0.000238855304432571	0.00264885047420839	CD34/EDN1/PROS1/CEACAM1/THBD/TFPI/THBS1/SH2B3/PDGFB/CD9	10
GO:1901654	response to ketone	23/988	194/18722	0.000240605695806061	0.00266270303358707	RAMP2/EDN1/CAV1/FOXO1/MSN/ADAM15/PRKCE/KLF2/TXNIP/AHR/THBS1/IGFBP7/CALM1/DUSP1/TGFB1/GNB1/CFLAR/KLF4/CCND1/PRKAA1/NR3C1/ROCK2/XRN1	23
GO:0048813	dendrite morphogenesis	19/988	146/18722	0.000248911935165093	0.00273947798278094	PREX2/ID1/ITGB1/MEF2A/NRP1/PDLIM5/FYN/PTEN/ACTR2/ABI2/ADAM10/RAPGEF2/PICALM/PPP3CA/DIP2A/WASL/CDC42/BTBD3/NEDD4	19
GO:0003382	epithelial cell morphogenesis	8/988	33/18722	0.000249090336160239	0.00273947798278094	COL15A1/HEG1/HOXA13/COL18A1/NOTCH4/FLNB/PALLD/CLIC4	8
GO:0034110	regulation of homotypic cell-cell adhesion	8/988	33/18722	0.000249090336160239	0.00273947798278094	CEACAM1/SH2B3/LGALS1/JAK1/IL6ST/RDX/CD9/F11R	8
GO:0034109	homotypic cell-cell adhesion	14/988	90/18722	0.000251880920608664	0.00276444514519261	CEACAM1/FN1/SH2B3/LGALS1/JAK1/IL6ST/PLPP3/MYH9/FLNA/RDX/VCL/CD9/F11R/MYL12A	14
GO:0044706	multi-multicellular organism process	25/988	220/18722	0.000256285092981111	0.00280698229673332	RAMP2/EDN1/CRHBP/IDO1/ITGA2/BMPR2/PCSK5/THBD/ETS1/ANGPT2/PAM/SLC38A2/TGFBR2/IGFBP7/TIMP1/SMURF2/GJA1/CAPN2/LNPEP/NR2F2/SLC2A1/EMP2/ASH1L/MAPK1/MAGED2	25
GO:0045927	positive regulation of growth	28/988	259/18722	0.00026130754603245	0.00285610223153164	EDN1/IGF1/HLX/MEF2C/FN1/BMPR2/AGRN/PLCB1/MACF1/PPM1F/NOTCH1/TGFBR2/IGF2/RPS6KA3/NRP1/ITSN2/GDI1/RHOA/SDCBP/CREB1/ADAM10/CELF1/RUFY3/NIPBL/RAB11A/CDC42/EIF4G2/MAPK1	28
GO:0002687	positive regulation of leukocyte migration	18/988	135/18722	0.000264931833989096	0.00288976981961002	EDN1/JAM2/PLVAP/SELP/VEGFC/ITGA2/IL1R1/THBS1/APP/MDK/JAM3/TNFRSF14/RHOA/ADAM10/MOSPD2/WNK1/PTK2/MAPK1	18
GO:0051235	maintenance of location	33/988	326/18722	0.000266252493556883	0.00289822386429131	APLNR/F2R/CAV1/SCARB1/PDE4D/ITPR1/CLIC2/FKBP1A/SRGN/PRKCE/TMSB4X/LTBP1/CALM1/CPT1A/PML/GJA1/TMSB10/ERO1A/ITPR2/FLNA/CD36/SUN1/HSP90B1/PKD2/ABCA1/VPS13C/SLC30A7/CCDC88A/SP100/STARD4/GSN/ARL2BP/YWHAB	33
GO:0051048	negative regulation of secretion	21/988	171/18722	0.000272337518070135	0.0029583985603038	FCGR2B/EDN1/CRHBP/STXBP6/P2RY1/CEACAM1/FOXF1/F2R/SYT11/NOTCH1/GNAI2/GJA1/CD200/MAP4K4/SLC30A1/TNFRSF1B/PPP3CA/PIM3/WNK1/MIDN/RAP1A	21
GO:0022408	negative regulation of cell-cell adhesion	23/988	196/18722	0.000279650162764634	0.00303163605021579	FCGR2B/PODXL/LRRC32/NOTCH4/HLX/CEACAM1/JAG1/PPM1F/NOTCH1/SH2B3/RGCC/MDK/TGFB1/PRKAR1A/KLF4/TNFRSF14/RDX/FXYD5/RC3H1/CD9/CBLB/WNK1/PTK2	23
GO:0002831	regulation of response to biotic stimulus	33/988	327/18722	0.000281562072100431	0.00304435167201527	A2M/FCGR2B/CEACAM1/FOXP1/SYT11/HLA-E/HLA-A/AHR/HLA-B/SEC14L1/IFI16/SASH1/CARD16/DDX60/TSPAN6/XIAP/ERAP1/FYN/CARD8/PARP14/LAMP1/ISG15/CD36/ADAR/HTRA1/PCBP2/PARP9/PLSCR1/PAK2/CRK/DTX3L/PUM2/ZMPSTE24	33
GO:0007520	myoblast fusion	9/988	42/18722	0.000281969319019487	0.00304435167201527	JAM2/EHD2/TANC1/CD81/CFLAR/MYH9/CAPN2/CD9/MYOF	9
GO:0014897	striated muscle hypertrophy	15/988	102/18722	0.000289432314632683	0.00311851683856423	EDN1/IGF1/SORBS2/FOXO1/LMCD1/NOTCH1/MEF2A/PDLIM5/IL6ST/ATP2B4/TNFRSF1B/PPP3CA/ROCK2/ROCK1/SMAD4	15
GO:0007272	ensheathment of neurons	18/988	136/18722	0.000290599743051448	0.00311851683856423	CLDN5/JAM2/MALL/CLDN11/ADGRG6/CLU/DICER1/JAM3/PTEN/SKI/QKI/SBF2/NDRG1/PPP3R1/CD9/TNFRSF1B/PLEC/B4GALT5	18
GO:0008366	axon ensheathment	18/988	136/18722	0.000290599743051448	0.00311851683856423	CLDN5/JAM2/MALL/CLDN11/ADGRG6/CLU/DICER1/JAM3/PTEN/SKI/QKI/SBF2/NDRG1/PPP3R1/CD9/TNFRSF1B/PLEC/B4GALT5	18
GO:0043484	regulation of RNA splicing	19/988	148/18722	0.000296983578688323	0.00317419873237902	NOVA2/SLC38A2/DDX17/MBNL1/SETX/QKI/TMBIM6/AHNAK/CELF1/SON/MBNL2/PTBP3/RBM5/DYRK1A/HNRNPH1/HNRNPK/HSPA1A/TIA1/RBM12	19
GO:0070507	regulation of microtubule cytoskeleton organization	19/988	148/18722	0.000296983578688323	0.00317419873237902	CDH5/BICD1/DIXDC1/MPDZ/PHLDB2/GIT1/TAOK1/RHOA/CYLD/APC/ARHGEF7/PRKAA1/DYNC1H1/DYRK1A/ROCK1/HSPA1A/CAMSAP2/SENP6/NIN	19
GO:0021537	telencephalon development	27/988	248/18722	0.000298253503150517	0.00318137070027218	NFIB/COL3A1/PLCB1/DIXDC1/SLC38A2/KIF5B/CDK6/MDK/PTEN/FLNA/RHOA/SUN1/HIF1A/SKI/TACC1/CELF1/ZMIZ1/RTN4/SLC2A1/ATP2B4/CRK/UBA6/HES1/BTBD3/ID2/BTG2/NIN	27
GO:0019883	antigen processing and presentation of endogenous antigen	7/988	26/18722	0.000302993763721882	0.00321900574578128	HLA-E/HLA-A/HLA-B/HLA-C/B2M/ERAP1/TAPBP	7
GO:0034063	stress granule assembly	7/988	26/18722	0.000302993763721882	0.00321900574578128	BICD1/CSDE1/G3BP1/PRKAA1/PUM2/DYNC1H1/DDX6	7
GO:0040014	regulation of multicellular organism growth	11/988	61/18722	0.000308245238888123	0.00326175041628229	IGF1/IGF2/APP/ADRB1/PIK3CA/PLAC8/CREB1/STAT3/CELF1/NIPBL/ZMPSTE24	11
GO:2000401	regulation of lymphocyte migration	11/988	61/18722	0.000308245238888123	0.00326175041628229	JAM2/MSN/APP/CD200/TNFRSF14/RHOA/ADAM10/LRCH1/CRK/WNK1/WASL	11
GO:0003208	cardiac ventricle morphogenesis	12/988	71/18722	0.00031265224168695	0.00329525537270055	CPE/HEG1/FOXF1/MEF2C/ENG/JAG1/FKBP1A/NOTCH1/TGFBR2/TGFB1/HIF1A/SMAD4	12
GO:0043550	regulation of lipid kinase activity	12/988	71/18722	0.00031265224168695	0.00329525537270055	TEK/PPP2R5A/CD81/PIK3R3/PDGFB/RB1/SOCS3/TGFB1/KLF4/SOCS4/CDC42/PTK2	12
GO:0021987	cerebral cortex development	16/988	114/18722	0.000317728443449814	0.00333267420941035	COL3A1/PLCB1/DIXDC1/SLC38A2/MDK/FLNA/RHOA/SUN1/HIF1A/TACC1/CELF1/ZMIZ1/RTN4/SLC2A1/CRK/BTBD3	16
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	27/988	249/18722	0.000318146464881935	0.00333267420941035	BST2/F2R/TNFSF10/FKBP1A/PRKCE/ANGPT1/MTDH/CARD16/LGALS1/TSPAN6/MAP3K3/GJA1/CFLAR/FYN/CARD8/ZMYND11/FLNA/CD36/RHOA/SLC44A2/S100A13/ASH1L/TRIM13/ZDHHC17/REL/PLK2/BCL10	27
GO:0045926	negative regulation of growth	27/988	249/18722	0.000318146464881935	0.00333267420941035	MEG3/BST2/ACVRL1/NPR1/HYAL2/BMPR2/ADAM15/CCDC85B/NOTCH1/TGFBR2/NRP1/RB1/ADRB1/PML/TGFB1/GJA1/PTEN/PLAC8/HIF1A/SEMA3F/RTN4/WWC2/SPAG9/WWC3/HSPA1A/SMAD4/SAV1	27
GO:0060216	definitive hemopoiesis	6/988	19/18722	0.000318712066713188	0.00333267420941035	TEK/LYL1/GATA2/ADAR/HIPK1/ZFP36L2	6
GO:0071357	cellular response to type I interferon	10/988	52/18722	0.000334310762529979	0.00348207602070441	IFI27/IFITM2/IFITM3/IFITM1/JAK1/OAS2/ISG15/ADAR/IFNAR1/SP100	10
GO:0072132	mesenchyme morphogenesis	10/988	52/18722	0.000334310762529979	0.00348207602070441	APLNR/ACVRL1/FOXF1/DCHS1/ENG/NOTCH1/TGFBR2/TBX3/SMAD2/SMAD4	10
GO:0045840	positive regulation of mitotic nuclear division	9/988	43/18722	0.000340103649456523	0.00352857536311142	EDN1/IGF1/HOXA13/IGF2/RGCC/PDGFB/RB1/CDC27/PHIP	9
GO:0061383	trabecula morphogenesis	9/988	43/18722	0.000340103649456523	0.00352857536311142	HEG1/TEK/S1PR1/ENG/ADGRG6/FKBP1A/NOTCH1/RHOA/SOS1	9
GO:0001558	regulation of cell growth	39/988	414/18722	0.000341831261660002	0.00353958608564899	MEG3/IGFBP4/BST2/EDN1/IGF1/ACVRL1/CEACAM1/NPR1/HYAL2/FN1/BMPR2/ADAM15/CCDC85B/MACF1/IGFBP7/RPS6KA3/NRP1/RB1/TTL/PML/TGFB1/GJA1/ITSN2/DPYSL2/GDI1/RHOA/SDCBP/KIAA1109/ADAM10/SEMA3F/RTN4/CTTN/RUFY3/SPAG9/RAB11A/CDC42/EIF4G2/HSPA1A/SMAD4	39
GO:0010506	regulation of autophagy	32/988	317/18722	0.000344103702211707	0.00355618456449141	KDR/LEPR/RASIP1/FOXO1/ITPR1/SPTLC2/IFI16/MTDH/FEZ2/TP53INP1/QSOX1/PIK3CA/HIF1A/PIK3C2A/RALB/STAT3/ATP6V1A/CTTN/VPS13C/TRIM13/PRKAA1/ATF6/WAC/SH3GLB1/SMG1/ROCK1/EIF4G2/NEDD4/PLK2/ZMPSTE24/CAPNS1/PAFAH1B2	32
GO:0051960	regulation of nervous system development	41/988	443/18722	0.000351603728722551	0.00362663884849357	JAM2/ADGRL2/VEGFC/PLXND1/FN1/BMPR2/AGRN/MACF1/ID1/NOTCH1/SKIL/B2M/NRP1/MDK/DICER1/PRKCH/IL6ST/TGFB1/PLXNA2/PTEN/GDI1/ACTR2/HIF1A/SKI/PCM1/NPTN/SEMA3F/RTN4/SPEN/RAPGEF2/CTNNA1/RUFY3/TNFRSF1B/PPP3CA/CTDSP1/HES1/RAB11A/EIF4G2/ID2/BHLHE40/NIN	41
GO:0061008	hepaticobiliary system development	19/988	150/18722	0.000352956027178299	0.00363353181467272	LIMS2/HLX/CEACAM1/ITGA2/NOTCH1/SULF2/MDK/CPT1A/CFLAR/PIK3CA/PKD2/ACAT1/RB1CC1/CCND1/NIPBL/ATF2/HES1/RAP1A/ZMPSTE24	19
GO:0097306	cellular response to alcohol	14/988	93/18722	0.000356960943715034	0.00364645930825602	LRP6/ADAM15/PRKCE/KLF2/AHR/GNB1/TP53INP1/KLF4/PTEN/ITPR2/ABCA1/CTNNA1/PRKAA1/XRN1	14
GO:0045428	regulation of nitric oxide biosynthetic process	11/988	62/18722	0.000357124382632933	0.00364645930825602	CD34/EDN1/CAV1/KLF2/CLU/DDAH2/KLF4/CD36/PKD2/ATP2B4/ROCK2	11
GO:0051057	positive regulation of small GTPase mediated signal transduction	12/988	72/18722	0.000357454995148716	0.00364645930825602	IGF1/COL3A1/F2R/LPAR6/NOTCH1/MAP4K4/ARPP19/F11R/SHOC2/ARHGEF3/SOS2/SOS1	12
GO:1903036	positive regulation of response to wounding	12/988	72/18722	0.000357454995148716	0.00364645930825602	F2R/SCARF1/THBD/PRKCE/THBS1/ITGB1/MDK/PLPP3/FLNA/CD36/FERMT2/PTK2	12
GO:0032868	response to insulin	28/988	264/18722	0.00035764406995508	0.00364645930825602	KL/CEACAM1/GRB14/TNFSF10/FOXO1/CAV2/IGF2/ZFP36L1/PIK3R3/PDK4/GNAI2/SOCS3/SHC1/CFLAR/TBC1D4/PIK3CA/PTEN/KBTBD2/OGT/PIK3C2A/EGR1/VPS13C/SLC2A1/MYO1C/APC/PRKAA1/PTPRA/PHIP	28
GO:0014896	muscle hypertrophy	15/988	104/18722	0.000358876160603303	0.0036520118105838	EDN1/IGF1/SORBS2/FOXO1/LMCD1/NOTCH1/MEF2A/PDLIM5/IL6ST/ATP2B4/TNFRSF1B/PPP3CA/ROCK2/ROCK1/SMAD4	15
GO:0008064	regulation of actin polymerization or depolymerization	22/988	187/18722	0.000362646359730733	0.00368332210877563	SPTBN1/ESAM/KANK3/CDC42EP5/PRKCE/SPTAN1/TMSB4X/ARHGAP28/NCKAP1/TMSB10/PIK3CA/TMOD3/RDX/ACTR2/RHOA/ABI2/CTTN/MYO1C/ADD1/GSN/WASL/DSTN	22
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	5/988	13/18722	0.000365309953796213	0.00370329479878909	PABPC1/ZFP36/TNRC6B/TNRC6A/BTG2	5
GO:0032232	negative regulation of actin filament bundle assembly	8/988	35/18722	0.000384450832688944	0.00387540016777744	CGNL1/S1PR1/DLC1/TJP1/ARHGAP28/PHLDB2/PAK2/F11R	8
GO:0098801	regulation of renal system process	8/988	35/18722	0.000384450832688944	0.00387540016777744	EDN1/F2R/NPR1/PDGFB/GNAI2/GJA1/EMP2/GJA5	8
GO:1901214	regulation of neuron death	32/988	319/18722	0.000384475882608944	0.00387540016777744	CD34/FCGR2B/NDNF/F2R/EFNB2/MEF2C/ITGA1/ANGPT1/CLU/NRP1/HIPK2/MDK/CD200/FYN/PIK3CA/MAP3K11/AP2B1/NCOA7/CAPN2/RHOA/HIF1A/CREB1/STAT3/EGR1/PICALM/TNFRSF1B/ATF2/GBE1/REL/CDC42/BTG2/JUN	32
GO:0003272	endocardial cushion formation	7/988	27/18722	0.000390557472451812	0.00392358400493175	APLNR/DCHS1/ENG/NOTCH1/TGFBR2/TBX3/SMAD4	7
GO:0030832	regulation of actin filament length	22/988	188/18722	0.000390733422177879	0.00392358400493175	SPTBN1/ESAM/KANK3/CDC42EP5/PRKCE/SPTAN1/TMSB4X/ARHGAP28/NCKAP1/TMSB10/PIK3CA/TMOD3/RDX/ACTR2/RHOA/ABI2/CTTN/MYO1C/ADD1/GSN/WASL/DSTN	22
GO:0050819	negative regulation of coagulation	10/988	53/18722	0.000392836532674621	0.00393725973880677	CD34/EDN1/PROS1/CEACAM1/THBD/TFPI/THBS1/SH2B3/PDGFB/CD9	10
GO:0070997	neuron death	35/988	361/18722	0.000398426784812776	0.00398576851398393	CD34/FCGR2B/NDNF/F2R/EFNB2/MEF2C/ITGA1/ANGPT1/CLU/NRP1/HIPK2/APP/RB1/XIAP/MDK/CD200/FYN/PIK3CA/MAP3K11/AP2B1/NCOA7/CAPN2/RHOA/HIF1A/CREB1/STAT3/EGR1/PICALM/TNFRSF1B/ATF2/GBE1/REL/CDC42/BTG2/JUN	35
GO:0019080	viral gene expression	14/988	94/18722	0.000399436554267937	0.00398835897795354	IFITM3/ST6GAL1/CANX/MDFIC/SPCS3/MGAT4A/ZFP36/CSDE1/PCBP2/PARP9/RSF1/TRIM13/JUN/CCNT1	14
GO:0050728	negative regulation of inflammatory response	21/988	176/18722	0.000403933535259125	0.00402569406997462	CDH5/FCGR2B/CALCRL/IGF1/TEK/NT5E/FOXF1/SYT11/GIT1/RB1/MDK/YES1/SOCS3/CD200/FYN/KLF4/ZFP36/ASH1L/TNFRSF1B/NR1D2/PLK2	21
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	20/988	164/18722	0.000413377092982744	0.00411209572645006	CAV1/CLU/RNF144B/HIPK2/PML/TRIB2/PTEN/RNF19A/OGT/RYBP/SDCBP/CSNK1A1/HECTD1/SOCS4/WAC/PTK2/HSPA1A/XPO1/PIAS1/PLK2	20
GO:0032388	positive regulation of intracellular transport	23/988	202/18722	0.000432205666710846	0.0042913579468561	ABLIM3/EHD2/HYAL2/MSN/CD81/KIF5B/STOM/TGFB1/FYN/FLNA/RDX/PCM1/MYO1C/RUFY3/LEPROT/PRKAA1/SH3GLB1/DYNC1H1/CDC42/MAPK1/NEDD4/OAZ2/CTDSPL2	23
GO:0046822	regulation of nucleocytoplasmic transport	15/988	106/18722	0.000442161749177936	0.00437386072929832	IFI27/HYAL2/ANGPT1/PKIG/MDFIC/TGFB1/FLNA/CD36/SP100/PTPN14/MAPK1/XPO1/NEDD4/PPP1R12A/CTDSPL2	15
GO:1905477	positive regulation of protein localization to membrane	15/988	106/18722	0.000442161749177936	0.00437386072929832	SPTBN1/RAMP3/PRKCE/ITGB1/CD81/KIF5B/STOM/PRKCH/STX3/FYN/AP2B1/ACSL3/MYO1C/ATP2B4/RAB11A	15
GO:0007249	I-kappaB kinase/NF-kappaB signaling	29/988	281/18722	0.000445884955488548	0.00440249234861555	BST2/F2R/TNFSF10/FKBP1A/PRKCE/ANGPT1/MTDH/CARD16/LGALS1/TSPAN6/MAP3K3/GJA1/CFLAR/FYN/CARD8/ZMYND11/FLNA/CD36/RHOA/SLC44A2/S100A13/ASH1L/TRIM13/ZDHHC17/ROCK2/REL/ROCK1/PLK2/BCL10	29
GO:0032869	cellular response to insulin stimulus	23/988	203/18722	0.000463698769501822	0.00455636156492331	KL/CEACAM1/GRB14/FOXO1/CAV2/IGF2/ZFP36L1/PIK3R3/PDK4/GNAI2/SOCS3/SHC1/CFLAR/TBC1D4/PIK3CA/PTEN/OGT/PIK3C2A/MYO1C/APC/PRKAA1/PTPRA/PHIP	23
GO:0007611	learning or memory	27/988	255/18722	0.00046404209462039	0.00455636156492331	CLDN5/CRHBP/MEF2C/TANC1/SYT11/THRA/PLCB1/RCAN1/ITGB1/B2M/GIT1/APP/MDK/FYN/PTEN/ACTR2/HIF1A/CREB1/NPTN/PJA2/PICALM/UBA6/MAPK1/PIAS1/BTG2/PLK2/JUN	27
GO:0043547	positive regulation of GTPase activity	27/988	255/18722	0.00046404209462039	0.00455636156492331	ARHGAP29/S1PR1/ARHGEF15/F2R/RALGAPA2/PKP4/AGRN/CAV2/NEDD9/ITGB1/ASAP2/ADRB1/LIMS1/TBC1D4/ITGA6/FERMT2/MAP4K4/TBC1D15/DOCK9/RAPGEF2/PICALM/ARHGEF7/F11R/CRK/MYO9A/RALGAPB/RAP1A	27
GO:0070372	regulation of ERK1 and ERK2 cascade	31/988	309/18722	0.000470008505469354	0.00458891516504164	KDR/IGF1/TEK/RAMP3/P2RY1/CEACAM1/F2R/FN1/ANGPT1/NOTCH1/NRP1/PDGFB/APP/GNAI2/DUSP1/SHC1/TGFB1/DUSP6/CFLAR/KLF4/PTEN/RRAS/CD36/FERMT2/NPTN/RAPGEF2/CD44/ZDHHC17/SYNJ2BP/SMAD4/RAP1A	31
GO:0051101	regulation of DNA binding	16/988	118/18722	0.000471286913557889	0.00458891516504164	IGF1/ITGA2/ID1/IFI16/TMSB4X/HIPK2/RB1/CALM1/TGFB1/KLF4/SKI/RSF1/SP100/HES1/JUN/ZMPSTE24	16
GO:0001649	osteoblast differentiation	25/988	229/18722	0.000471433844589686	0.00458891516504164	IGF1/VEGFC/WWTR1/MEF2C/SMAD6/BMPR2/JAG1/ID3/HDAC7/NOTCH1/IGF2/IFITM1/SMAD5/SMAD1/CRIM1/PDLIM7/CDK6/IL6ST/SKI/FERMT2/BCAP29/ADAR/NBR1/TPM4/PTK2	25
GO:0003203	endocardial cushion morphogenesis	8/988	36/18722	0.000471676897611584	0.00458891516504164	APLNR/ACVRL1/DCHS1/ENG/NOTCH1/TGFBR2/TBX3/SMAD4	8
GO:0097009	energy homeostasis	8/988	36/18722	0.000471676897611584	0.00458891516504164	LEPR/FOXO1/PRCP/PIK3CA/CD36/STAT3/PRKAA1/NR1D2	8
GO:0080164	regulation of nitric oxide metabolic process	11/988	64/18722	0.000474562527942403	0.00460854871742238	CD34/EDN1/CAV1/KLF2/CLU/DDAH2/KLF4/CD36/PKD2/ATP2B4/ROCK2	11
GO:0050890	cognition	30/988	296/18722	0.000486080186864015	0.00470402612474711	CLDN5/CRHBP/SHROOM4/MEF2C/TANC1/SYT11/THRA/PLCB1/RCAN1/ITGB1/B2M/GIT1/APP/MDK/FYN/PTEN/ACTR2/HIF1A/CREB1/NPTN/MAGT1/PJA2/PICALM/NIPBL/UBA6/MAPK1/PIAS1/BTG2/PLK2/JUN	30
GO:0085029	extracellular matrix assembly	9/988	45/18722	0.00048616535061863	0.00470402612474711	RAMP2/TIE1/LAMB2/NOTCH1/RGCC/PHLDB2/TGFB1/QSOX1/LTBP3	9
GO:0071277	cellular response to calcium ion	13/988	85/18722	0.000490322095951058	0.00473561995216731	EDN1/CRHBP/MEF2C/RASA4/SYT11/MEF2A/PKD2/CLIC4/ADD1/IQGAP1/PRKAA1/WNK1/CPNE8	13
GO:0044331	cell-cell adhesion mediated by cadherin	7/988	28/18722	0.000497231769077935	0.00478699056693731	CDH5/NOTCH4/TJP1/PPM1F/NOTCH1/RGCC/CTNND1	7
GO:0010769	regulation of cell morphogenesis involved in differentiation	14/988	96/18722	0.000497443296865473	0.00478699056693731	LIMS2/NEDD9/NRP1/ACTN4/MDK/LIMS1/FLNA/ACTR2/FERMT2/ARHGEF7/CRK/CDC42/PTK2/DOCK1	14
GO:0030282	bone mineralization	16/988	119/18722	0.000518382688576188	0.00497947349315861	MGP/IGF1/KL/S1PR1/CLEC3B/MEF2C/BMPR2/SRGN/BCOR/TGFB1/ISG15/HIF1A/NBR1/LTBP3/KLF10/ZMPSTE24	16
GO:0007254	JNK cascade	20/988	167/18722	0.00052351300570473	0.0050196770510894	FCGR2B/MECOM/CDC42EP5/PLCB1/MAP4K2/MDFIC/HIPK2/APP/AIDA/TAOK1/MAP3K11/ZMYND11/MAP4K4/SDCBP/CYLD/HIPK3/RB1CC1/PJA2/ATF2/CDC42	20
GO:0000768	syncytium formation by plasma membrane fusion	10/988	55/18722	0.000535605303423463	0.00510796296550348	JAM2/CD109/EHD2/TANC1/CD81/CFLAR/MYH9/CAPN2/CD9/MYOF	10
GO:0048016	inositol phosphate-mediated signaling	10/988	55/18722	0.000535605303423463	0.00510796296550348	EDN1/IGF1/LMCD1/ITPR1/RCAN1/ITPR2/NFAT5/PPP3R1/ATP2B4/PPP3CA	10
GO:0140253	cell-cell fusion	10/988	55/18722	0.000535605303423463	0.00510796296550348	JAM2/CD109/EHD2/TANC1/CD81/CFLAR/MYH9/CAPN2/CD9/MYOF	10
GO:0048545	response to steroid hormone	33/988	339/18722	0.000536733114525223	0.0051095453483118	SPARC/RAMP2/EDN1/PLPP1/ENG/CAV1/FOXO1/TFPI/FOXP1/PAM/TXNIP/THBS1/NOTCH1/TGFBR2/IGFBP7/ZFP36L1/DDX17/MDK/PKN1/CALM1/DUSP1/TGFB1/CFLAR/RHOA/ZFP36/ZMIZ1/CLOCK/CCND1/ZFP36L2/NR3C1/CNOT2/NEDD4/ARID1A	33
GO:0001819	positive regulation of cytokine production	42/988	467/18722	0.000541349166625899	0.00513616809560082	CD34/SPTBN1/IL33/HEG1/F2R/HYAL2/PDE4D/FOXP1/IL1R1/PLCB1/HLA-E/HLA-A/THBS1/IFI16/RGCC/CLU/B2M/CD81/SULF2/APP/MDK/IL6ST/TGFB1/CD200/OAS2/CARD8/TNFRSF14/PDE4B/ISG15/CD36/HIF1A/CREB1/STAT3/EIF2AK2/EGR1/S100A13/G3BP1/CD46/ATF2/ROCK2/HSPA1A/BCL10	42
GO:0007173	epidermal growth factor receptor signaling pathway	15/988	108/18722	0.000541463504054303	0.00513616809560082	CEACAM1/HIP1/ITGA1/SHC1/TGFB1/PIK3CA/PIK3C2A/CCDC88A/IQGAP1/SOCS4/EFEMP1/CBLB/PTK2/SOS1/PTPN12	15
GO:0003214	cardiac left ventricle morphogenesis	5/988	14/18722	0.000543649240370043	0.00513681451448238	CPE/FOXF1/NOTCH1/TGFBR2/SMAD4	5
GO:0034616	response to laminar fluid shear stress	5/988	14/18722	0.000543649240370043	0.00513681451448238	SMAD6/ETS1/KLF2/KLF4/ABCA1	5
GO:0072577	endothelial cell apoptotic process	11/988	65/18722	0.000544432713037194	0.00513681451448238	CDH5/RAMP2/KDR/TEK/NDNF/BMPR2/THBS1/ANGPT1/RGCC/GATA2/HIPK1	11
GO:0048660	regulation of smooth muscle cell proliferation	21/988	180/18722	0.000546179313511034	0.00514063235482694	EDN1/CALCRL/IGF1/S1PR1/ITGA2/NPR1/MEF2C/BMPR2/FOXP1/THBS1/TGFBR2/PDGFB/GNAI2/TGFB1/GJA1/IGFBP3/KLF4/PTEN/RHOA/ID2/JUN	21
GO:0048608	reproductive structure development	39/988	424/18722	0.000546772831415139	0.00514063235482694	HSD17B2/RSPO3/HOXA13/FZD4/PCDH12/TNFSF10/BMPR2/EPAS1/ADAM15/NOTCH1/VASH1/IGF2/ZFP36L1/PDGFB/SOCS3/GJA1/ATRX/PTEN/FLNA/RNF38/FNDC3A/HIF1A/CSDE1/GATA2/NR2F2/PKD2/HTRA1/TBX3/FEM1B/CTNNA1/HECTD1/ASH1L/CCND1/NIPBL/HES1/BPTF/PTK2/MAPK1/SMAD4	39
GO:0035023	regulation of Rho protein signal transduction	13/988	86/18722	0.000550248847031533	0.00516417292479064	HEG1/COL3A1/RASIP1/F2R/LPAR6/DLC1/ITGB1/NRP1/ABCA1/TNFAIP1/STARD13/F11R/ARHGEF3	13
GO:0048675	axon extension	16/988	120/18722	0.000569455472283719	0.00533500435409368	FN1/BMPR2/MACF1/LAMB2/ITGB1/NRP1/TTL/DPYSL2/GDI1/SEMA3F/VCL/RTN4/CTTN/RUFY3/RAB11A/EIF4G2	16
GO:0030513	positive regulation of BMP signaling pathway	8/988	37/18722	0.000574278678400317	0.00536128003455621	CDH5/ACVRL1/ENG/BMPR2/NOTCH1/SMAD2/HES1/SMAD4	8
GO:1902745	positive regulation of lamellipodium organization	8/988	37/18722	0.000574278678400317	0.00536128003455621	FSCN1/ENPP2/NCKAP1/PIK3CA/ACTR2/ABI2/ARHGEF7/CDC42	8
GO:0001974	blood vessel remodeling	9/988	46/18722	0.000576498910624876	0.00536315624034911	ACVRL1/RSPO3/CEACAM1/MEF2C/BMPR2/JAG1/EPAS1/TGFB1/FLNA	9
GO:0031294	lymphocyte costimulation	9/988	46/18722	0.000576498910624876	0.00536315624034911	CAV1/CD81/LGALS1/YES1/EFNB1/FYN/PIK3CA/TNFRSF14/CD320	9
GO:0051962	positive regulation of nervous system development	28/988	272/18722	0.000577600219907892	0.00536400763662714	ADGRL2/VEGFC/PLXND1/FN1/BMPR2/AGRN/MACF1/NOTCH1/SKIL/NRP1/MDK/DICER1/PRKCH/IL6ST/TGFB1/PLXNA2/GDI1/ACTR2/HIF1A/NPTN/SPEN/RUFY3/TNFRSF1B/HES1/RAB11A/EIF4G2/ID2/NIN	28
GO:0003177	pulmonary valve development	6/988	21/18722	0.000582112401632268	0.00539647657499234	SMAD6/BMPR2/JAG1/NOTCH1/TNFRSF1B/GJA5	6
GO:0030323	respiratory tube development	21/988	181/18722	0.00058789558443744	0.00544059467688447	SPARC/NFIB/HEG1/FOXF1/BMPR2/PCSK5/EPAS1/THRA/KLF2/NOTCH1/TGFBR2/CREB1/PPP3R1/HECA/LIPA/LTBP3/SMAD2/HES1/CDC42/MAPK1/SAV1	21
GO:0001937	negative regulation of endothelial cell proliferation	12/988	76/18722	0.000594854431838742	0.00547637216971819	SPARC/ACVRL1/MEF2C/CAV1/CAV2/THBS1/VASH1/RGCC/GJA1/PTPRM/NR2F2/SYNJ2BP	12
GO:0006809	nitric oxide biosynthetic process	12/988	76/18722	0.000594854431838742	0.00547637216971819	CD34/EDN1/CAV1/KLF2/CLU/DDAH2/KLF4/CD36/PKD2/ATP2B4/ROCK2/CYB5R3	12
GO:0014855	striated muscle cell proliferation	12/988	76/18722	0.000594854431838742	0.00547637216971819	MEF2C/ANGPT1/NOTCH1/TGFBR2/SMAD1/GJA1/CFLAR/PRKAR1A/PTEN/STAT3/MAPK1/SAV1	12
GO:0072009	nephron epithelium development	15/988	109/18722	0.000597865263080881	0.00549456795412741	PECAM1/CD34/PODXL/DCHS1/WWTR1/MEF2C/JAG1/LAMB2/NOTCH1/PKD2/ACAT1/IQGAP1/HES1/SMAD4/MTSS1	15
GO:0016050	vesicle organization	30/988	300/18722	0.000607201171011092	0.00557072991435392	CD34/STXBP6/F2R/CAV1/CAV2/SYT11/SRGN/TMCC1/KIF5B/SCARB2/STX3/TBC1D4/LYST/SAMD9/RAB27A/DYSF/SDCBP/CREB1/MFSD14A/ABCA1/SNAP23/YIPF4/PICALM/SEC23A/PDCD6IP/SEC31A/RAB11A/CLCN3/WASL/VPS36	30
GO:0031214	biomineral tissue development	20/988	169/18722	0.000610338928320969	0.00558986273662239	MGP/IGF1/KL/S1PR1/CLEC3B/MEF2C/BMPR2/FOXO1/SRGN/NOTCH1/BCOR/TGFB1/ISG15/HIF1A/NBR1/LTBP3/KLF10/ROCK2/ROCK1/ZMPSTE24	20
GO:0043502	regulation of muscle adaptation	14/988	98/18722	0.000615194747816172	0.00562460277356137	EDN1/IGF1/FOXO1/LMCD1/NOTCH1/MEF2A/IL6ST/KLF4/ATP2B4/TNFRSF1B/PPP3CA/ROCK2/ROCK1/SMAD4	14
GO:2000177	regulation of neural precursor cell proliferation	13/988	87/18722	0.000616249776771973	0.00562460277356137	VEGFC/LIMS2/NOTCH1/MDK/GNAI2/FLNA/RHOA/HIF1A/GATA2/CTNNA1/ID2/BTG2/SLC16A2	13
GO:0045599	negative regulation of fat cell differentiation	10/988	56/18722	0.000621674263615372	0.00566438025441657	WWTR1/FOXO1/JAG1/CCDC85B/ZADH2/TGFB1/TRIB2/FERMT2/GATA2/ZFP36L2	10
GO:0043500	muscle adaptation	16/988	121/18722	0.000624774450382158	0.00566722872464217	EDN1/IGF1/FOXO1/LMCD1/NOTCH1/MEF2A/IL6ST/CFLAR/KLF4/ATP2B4/TNFRSF1B/PPP3CA/GSN/ROCK2/ROCK1/SMAD4	16
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	7/988	29/18722	0.000625874432382346	0.00566722872464217	PABPC1/ZFP36/TNRC6B/CNOT6L/TNRC6A/CNOT2/BTG2	7
GO:0061458	reproductive system development	39/988	427/18722	0.000626599768836328	0.00566722872464217	HSD17B2/RSPO3/HOXA13/FZD4/PCDH12/TNFSF10/BMPR2/EPAS1/ADAM15/NOTCH1/VASH1/IGF2/ZFP36L1/PDGFB/SOCS3/GJA1/ATRX/PTEN/FLNA/RNF38/FNDC3A/HIF1A/CSDE1/GATA2/NR2F2/PKD2/HTRA1/TBX3/FEM1B/CTNNA1/HECTD1/ASH1L/CCND1/NIPBL/HES1/BPTF/PTK2/MAPK1/SMAD4	39
GO:2001233	regulation of apoptotic signaling pathway	34/988	356/18722	0.000626791183616689	0.00566722872464217	IGF1/TNFSF10/HYAL2/CAV1/FGFR1/THBS1/SKIL/CLU/SERINC3/PCGF2/NRP1/PEA15/RB1/GNAI2/PML/CFLAR/FYN/ZMYND11/PTEN/ITGA6/HIF1A/TMBIM6/CYLD/RB1CC1/CTTN/FEM1B/CTNNA1/CD44/SP100/PAK2/PHIP/HNRNPK/HSPA1A/BCL10	34
GO:1990845	adaptive thermogenesis	19/988	157/18722	0.000627321251899397	0.00566722872464217	FABP4/LAMA4/LEPR/NOVA2/CAV1/EPAS1/THRA/FABP5/ID1/NOTCH1/RB1/ADRB1/GJA1/CD36/PLAC8/OGT/LNPEP/APC/DYNC1H1	19
GO:0006913	nucleocytoplasmic transport	30/988	301/18722	0.000641343955030851	0.00577426964258285	IFI27/HYAL2/HHEX/TXNIP/ANGPT1/NOTCH1/PKIG/MDFIC/IPO11/PML/TGFB1/KPNA3/FLNA/CD36/RANBP2/ZC3H11A/STAT3/PPP3R1/FYTTD1/THOC2/PPP3CA/SP100/PTPN14/CBLB/SMG1/MAPK1/XPO1/NEDD4/PPP1R12A/CTDSPL2	30
GO:0051169	nuclear transport	30/988	301/18722	0.000641343955030851	0.00577426964258285	IFI27/HYAL2/HHEX/TXNIP/ANGPT1/NOTCH1/PKIG/MDFIC/IPO11/PML/TGFB1/KPNA3/FLNA/CD36/RANBP2/ZC3H11A/STAT3/PPP3R1/FYTTD1/THOC2/PPP3CA/SP100/PTPN14/CBLB/SMG1/MAPK1/XPO1/NEDD4/PPP1R12A/CTDSPL2	30
GO:0060560	developmental growth involved in morphogenesis	25/988	234/18722	0.000649201016642659	0.00583511979764095	S1PR1/NRN1/FN1/BMPR2/MACF1/LAMB2/NOTCH1/TGFBR2/ITGB1/NRP1/APP/TTL/ITSN2/DPYSL2/GDI1/SEMA3F/VCL/RTN4/CTTN/IQGAP1/RUFY3/SPAG9/RAB11A/EIF4G2/NIN	25
GO:0050863	regulation of T cell activation	32/988	329/18722	0.000656094170845507	0.00588711526272185	FCGR2B/IGF1/LRRC32/HLX/CEACAM1/CAV1/HLA-E/HLA-A/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/PRKAR1A/FYN/PIK3CA/TNFRSF14/RHOA/ZMIZ1/RC3H1/TNFRSF1B/CBLB/CD46/HES1/SOS2/SOS1/HSPH1/BCL10	32
GO:0010761	fibroblast migration	9/988	47/18722	0.000680117850956128	0.00609238789928997	HYAL2/PRKCE/THBS1/ITGB1/PML/TGFB1/ARHGEF7/PLEC/PTK2	9
GO:0045664	regulation of neuron differentiation	22/988	196/18722	0.000692649304675401	0.0061941971488817	TCF4/ZEB1/MEF2C/JAG1/FGFR1/DIXDC1/NOTCH1/B2M/APP/DPYSL2/MIB1/PTEN/TUG1/RHOA/TCF12/GATA2/SPAG9/CTDSP1/HES1/DDX6/ROCK1/ID2	22
GO:0042552	myelination	17/988	134/18722	0.000694397846405069	0.00619939724387181	CLDN5/JAM2/MALL/ADGRG6/CLU/DICER1/JAM3/PTEN/SKI/QKI/SBF2/NDRG1/PPP3R1/CD9/TNFRSF1B/PLEC/B4GALT5	17
GO:0030833	regulation of actin filament polymerization	20/988	171/18722	0.000709350983041497	0.00631167909868749	SPTBN1/ESAM/KANK3/CDC42EP5/PRKCE/SPTAN1/TMSB4X/ARHGAP28/NCKAP1/TMSB10/TMOD3/RDX/ACTR2/RHOA/ABI2/CTTN/MYO1C/ADD1/GSN/WASL	20
GO:0110148	biomineralization	20/988	171/18722	0.000709350983041497	0.00631167909868749	MGP/IGF1/KL/S1PR1/CLEC3B/MEF2C/BMPR2/FOXO1/SRGN/NOTCH1/BCOR/TGFB1/ISG15/HIF1A/NBR1/LTBP3/KLF10/ROCK2/ROCK1/ZMPSTE24	20
GO:0006949	syncytium formation	10/988	57/18722	0.000718851421539289	0.00637485601204792	JAM2/CD109/EHD2/TANC1/CD81/CFLAR/MYH9/CAPN2/CD9/MYOF	10
GO:0051785	positive regulation of nuclear division	10/988	57/18722	0.000718851421539289	0.00637485601204792	EDN1/IGF1/HOXA13/PLCB1/IGF2/RGCC/PDGFB/RB1/CDC27/PHIP	10
GO:0003002	regionalization	32/988	331/18722	0.000727242695288555	0.00643852199562134	EDN1/ACVRL1/MEOX2/LRP6/TCF15/FOXF1/MEF2C/HHEX/SMAD6/BMPR2/PCSK5/TSHZ1/NOTCH1/PCGF2/NRP1/HIPK2/CHSY1/AIDA/PLXNA2/MIB1/SKI/NR2F2/SEMA3F/TBX3/HIPK1/SMAD2/ETS2/HES1/BPTF/BTG2/SMAD4/BHLHE40	32
GO:0048659	smooth muscle cell proliferation	21/988	184/18722	0.000730055358888861	0.00645266899570321	EDN1/CALCRL/IGF1/S1PR1/ITGA2/NPR1/MEF2C/BMPR2/FOXP1/THBS1/TGFBR2/PDGFB/GNAI2/TGFB1/GJA1/IGFBP3/KLF4/PTEN/RHOA/ID2/JUN	21
GO:0034504	protein localization to nucleus	29/988	290/18722	0.000742604757445336	0.00655268516868709	HYAL2/WWTR1/HHEX/TXNIP/ANGPT1/NOTCH1/PKIG/MDFIC/IPO11/PML/TGFB1/FYN/KPNA3/FLNA/CD36/SUN1/RANBP2/FERMT2/STAT3/PARP9/PPP3R1/CTNNA1/PPP3CA/SP100/CBLB/DTX3L/ARL2BP/MAPK1/XPO1	29
GO:0001889	liver development	18/988	147/18722	0.000750017655449083	0.00660712070604566	LIMS2/HLX/CEACAM1/ITGA2/NOTCH1/SULF2/MDK/CPT1A/CFLAR/PIK3CA/PKD2/ACAT1/RB1CC1/CCND1/ATF2/HES1/RAP1A/ZMPSTE24	18
GO:1990138	neuron projection extension	20/988	172/18722	0.000763852284961607	0.00671635923563897	NRN1/FN1/BMPR2/MACF1/LAMB2/ITGB1/NRP1/TTL/ITSN2/DPYSL2/GDI1/SEMA3F/VCL/RTN4/CTTN/IQGAP1/RUFY3/SPAG9/RAB11A/EIF4G2	20
GO:0061042	vascular wound healing	6/988	22/18722	0.000764946787944573	0.00671635923563897	CD34/KDR/MCAM/NDNF/SLC12A2/GATA2	6
GO:0010498	proteasomal protein catabolic process	43/988	490/18722	0.000772260775507597	0.00676938818398738	IFI27/WWTR1/CAV1/HACE1/CLU/RNF144B/CANX/SMURF2/DNAJC10/PML/TRIB2/ATXN3/SEL1L/RNF19A/PSMB8/OGT/RYBP/SDCBP/HSP90B1/EDEM3/PCBP2/SPOP/TNFAIP1/MAN1A1/ENC1/FEM1B/CSNK1A1/TBL1XR1/PPP2CB/HECTD1/CRBN/CLOCK/SOCS4/CDC27/TRIM13/WAC/APPBP2/HSPA1A/XPO1/PIAS1/NEDD4/PLK2/TMTC3	43
GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	5/988	15/18722	0.000780205226917485	0.00680533688897484	PABPC1/ZFP36/TNRC6B/TNRC6A/BTG2	5
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	5/988	15/18722	0.000780205226917485	0.00680533688897484	ZFP36L1/PABPC1/ZFP36/TNRC6B/ZFP36L2	5
GO:2000345	regulation of hepatocyte proliferation	5/988	15/18722	0.000780205226917485	0.00680533688897484	LIMS2/CEACAM1/SULF2/MDK/CFLAR	5
GO:0014074	response to purine-containing compound	18/988	148/18722	0.000812745450692881	0.00707754726898457	SPARC/CRHBP/TEK/P2RY1/THBD/AHR/ZFP36L1/APP/DUSP1/PTEN/ITPR2/HSP90B1/PKD2/RAPGEF2/PRKAA1/XRN1/JUN/RAP1A	18
GO:0010508	positive regulation of autophagy	16/988	124/18722	0.000819097224369312	0.00712118568878852	KDR/FOXO1/SPTLC2/MTDH/TP53INP1/HIF1A/PIK3C2A/RALB/TRIM13/PRKAA1/ATF6/WAC/SH3GLB1/ROCK1/PLK2/PAFAH1B2	16
GO:0043666	regulation of phosphoprotein phosphatase activity	10/988	58/18722	0.000828202732320855	0.00718858319295487	NUAK1/FKBP1A/ITGA1/RCAN1/GNAI2/CALM1/HSP90B1/ROCK2/ROCK1/PPP1R12A	10
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	12/988	79/18722	0.000849545035758159	0.00733785891048348	LIMS2/NEDD9/NRP1/MDK/LIMS1/FLNA/ACTR2/FERMT2/ARHGEF7/CRK/CDC42/DOCK1	12
GO:0032272	negative regulation of protein polymerization	12/988	79/18722	0.000849545035758159	0.00733785891048348	CDH5/SPTBN1/KANK3/SPTAN1/TMSB4X/TMSB10/TMOD3/RDX/ADD1/ARHGEF7/GSN/DYRK1A	12
GO:0050772	positive regulation of axonogenesis	12/988	79/18722	0.000849545035758159	0.00733785891048348	PLXND1/FN1/BMPR2/MACF1/SKIL/NRP1/PLXNA2/GDI1/RUFY3/RAB11A/EIF4G2/NIN	12
GO:0090257	regulation of muscle system process	26/988	252/18722	0.000863171781644789	0.00744345536379402	EDN1/CALCRL/IGF1/ITGA2/F2R/CAV1/FOXO1/LMCD1/PDE4D/CLIC2/NOTCH1/DOCK4/MEF2A/CALM1/IL6ST/KLF4/PDE4B/RHOA/CTTN/ATP2B4/TNFRSF1B/PPP3CA/GJA5/ROCK2/ROCK1/SMAD4	26
GO:0045834	positive regulation of lipid metabolic process	18/988	149/18722	0.000879912514192885	0.00757551908491509	ADGRF5/TEK/ZBTB20/SCARB1/PRKCE/CD81/PDGFB/CPT1A/TGFB1/LPGAT1/ACSL3/CAPN2/ELOVL5/CREB1/STARD4/PRKAA1/CDC42/PTK2	18
GO:0018210	peptidyl-threonine modification	16/988	125/18722	0.000894357198582585	0.0076750007089995	EOGT/CDC42BPA/TGFBR2/HIPK2/APP/PKN1/CALM1/TGFB1/HIPK3/HIPK1/WNK1/CDC42BPB/ROCK2/DYRK1A/ROCK1/MAPK1	16
GO:1904375	regulation of protein localization to cell periphery	16/988	125/18722	0.000894357198582585	0.0076750007089995	SPTBN1/RAMP3/PRKCE/PPP2R5A/ITGB1/KIF5B/PRKCH/TGFB1/STX3/ACSL3/ADAM10/ATP2B4/PICALM/HECTD1/RAB11A/RAP1A	16
GO:0071241	cellular response to inorganic substance	24/988	226/18722	0.000897689587883742	0.00769117272715877	EDN1/FABP4/CRHBP/MEF2C/FOXO1/RASA4/SYT11/B2M/MEF2A/APP/SLC12A2/ATRX/CFLAR/CREB1/PKD2/CLIC4/ADD1/IQGAP1/PRKAA1/CRK/WNK1/MAPK1/JUN/CPNE8	24
GO:0021700	developmental maturation	28/988	280/18722	0.000908414456839676	0.00777052752774937	CDH5/IGF1/ACVRL1/NFIA/SOX18/S1PR1/ARHGEF15/DCHS1/SCARF1/RPS6KA2/AGRN/EPAS1/KLF2/APP/ANKS1A/RB1/CDC25B/PTEN/LYL1/RHOA/HIF1A/GATA2/FEM1B/PICALM/PTBP3/HES1/B4GALT5/CLCN3	28
GO:0003143	embryonic heart tube morphogenesis	11/988	69/18722	0.000915572981840596	0.00779410846079687	APLNR/SOX18/MEF2C/ENG/NOTCH1/TGFBR2/MIB1/HIF1A/PKD2/TBX3/HES1	11
GO:0045665	negative regulation of neuron differentiation	11/988	69/18722	0.000915572981840596	0.00779410846079687	JAG1/DIXDC1/NOTCH1/B2M/APP/MIB1/RHOA/SPAG9/CTDSP1/HES1/DDX6	11
GO:0045669	positive regulation of osteoblast differentiation	11/988	69/18722	0.000915572981840596	0.00779410846079687	IGF1/WWTR1/MEF2C/BMPR2/JAG1/IFITM1/SMAD5/SMAD1/PDLIM7/IL6ST/FERMT2	11
GO:0072091	regulation of stem cell proliferation	9/988	49/18722	0.000932994952924783	0.00792971070389831	SOX18/VEGFC/ZFP36L1/GJA1/N4BP2L2/FERMT2/EIF2AK2/TBX3/LTBP3	9
GO:0032886	regulation of microtubule-based process	25/988	240/18722	0.000937477549557743	0.00795508105950596	CDH5/BICD1/MACF1/DIXDC1/MPDZ/PHLDB2/GIT1/TAOK1/LAMP1/RHOA/CYLD/APC/ARHGEF7/PRKAA1/PDCD6IP/ROCK2/DYNC1H1/DYRK1A/ROCK1/HSPA1A/XPO1/PLK2/CAMSAP2/SENP6/NIN	25
GO:0014033	neural crest cell differentiation	13/988	91/18722	0.000950987808659372	0.00805685365167238	EDN1/LRP6/MEF2C/FN1/JAG1/NRP1/EFNB1/HIF1A/PHACTR4/SEMA3F/HES1/MAPK1/SMAD4	13
GO:0007411	axon guidance	24/988	227/18722	0.000954958573322858	0.00807761137180099	NFIB/ROBO4/LAMA2/NOVA2/EFNB2/PLXND1/BMPR2/LAMB2/NOTCH1/NRP1/KIF5B/APP/FEZ2/EFNB1/DPYSL2/FYN/PLXNA2/PALLD/PTPRM/NPTN/SEMA3F/PTK2/SOS1/SMAD4	24
GO:0001782	B cell homeostasis	7/988	31/18722	0.000961593004405106	0.00809505869952444	MEF2C/PKN1/HIF1A/RC3H1/SOS2/SOS1/BCL10	7
GO:1905144	response to acetylcholine	7/988	31/18722	0.000961593004405106	0.00809505869952444	AGRN/PLCB1/GNAI2/GNAQ/GNB1/ATP2B4/ROCK2	7
GO:1905145	cellular response to acetylcholine	7/988	31/18722	0.000961593004405106	0.00809505869952444	AGRN/PLCB1/GNAI2/GNAQ/GNB1/ATP2B4/ROCK2	7
GO:0035162	embryonic hemopoiesis	6/988	23/18722	0.000989130847230483	0.00826551137630199	KDR/SH2B3/TGFBR2/KMT2A/HIF1A/GATA2	6
GO:0060487	lung epithelial cell differentiation	6/988	23/18722	0.000989130847230483	0.00826551137630199	NFIB/THRA/KLF2/CREB1/PPP3R1/SAV1	6
GO:0071636	positive regulation of transforming growth factor beta production	6/988	23/18722	0.000989130847230483	0.00826551137630199	CD34/THBS1/CD200/CREB1/CD46/ATF2	6
GO:1903306	negative regulation of regulated secretory pathway	6/988	23/18722	0.000989130847230483	0.00826551137630199	FCGR2B/CEACAM1/FOXF1/NOTCH1/GNAI2/RAP1A	6
GO:0010543	regulation of platelet activation	8/988	40/18722	0.000994288736720063	0.00826551137630199	SELP/CEACAM1/THBD/SH2B3/PDGFB/IL6ST/CD9/F11R	8
GO:0014037	Schwann cell differentiation	8/988	40/18722	0.000994288736720063	0.00826551137630199	LAMA2/ADGRG6/LAMB2/DICER1/SKI/NDRG1/PPP3R1/PLEC	8
GO:0035329	hippo signaling	8/988	40/18722	0.000994288736720063	0.00826551137630199	DCHS1/WWTR1/PJA2/WWC2/WWC3/AMOTL2/SAV1/MOB1A	8
GO:0060412	ventricular septum morphogenesis	8/988	40/18722	0.000994288736720063	0.00826551137630199	APLNR/BMPR2/NOTCH1/TGFBR2/TBX3/HES1/SMAD4/SAV1	8
GO:0097485	neuron projection guidance	24/988	228/18722	0.00101536282844942	0.00842747812779982	NFIB/ROBO4/LAMA2/NOVA2/EFNB2/PLXND1/BMPR2/LAMB2/NOTCH1/NRP1/KIF5B/APP/FEZ2/EFNB1/DPYSL2/FYN/PLXNA2/PALLD/PTPRM/NPTN/SEMA3F/PTK2/SOS1/SMAD4	24
GO:0045639	positive regulation of myeloid cell differentiation	14/988	103/18722	0.00101694530871982	0.00842747812779982	JAG1/ETS1/ZFP36L1/RB1/TGFB1/ISG15/HIF1A/CREB1/STAT3/GATA2/KLF10/HSPA1A/ID2/JUN	14
GO:1903706	regulation of hemopoiesis	34/988	367/18722	0.00106535586030495	0.00880156409449828	FCGR2B/HLX/CEACAM1/MEF2C/JAG1/FOXP1/ETS1/HLA-B/TGFBR2/B2M/ZFP36L1/RB1/CDK6/MDK/TGFB1/GABPA/ISG15/RHOA/HIF1A/ZFP36/CREB1/STAT3/GATA2/ZMIZ1/RC3H1/ZFP36L2/CD46/KLF10/SOS2/PURB/SOS1/HSPA1A/ID2/JUN	34
GO:0046209	nitric oxide metabolic process	12/988	81/18722	0.00106540017183027	0.00880156409449828	CD34/EDN1/CAV1/KLF2/CLU/DDAH2/KLF4/CD36/PKD2/ATP2B4/ROCK2/CYB5R3	12
GO:1904036	negative regulation of epithelial cell apoptotic process	9/988	50/18722	0.00108536707088649	0.00886422489322996	CDH5/RAMP2/KDR/TEK/NDNF/ANGPT1/MDK/CFLAR/GATA2	9
GO:0001977	renal system process involved in regulation of blood volume	5/988	16/18722	0.00108583109658952	0.00886422489322996	F2R/PDGFB/GJA1/EMP2/GJA5	5
GO:0010649	regulation of cell communication by electrical coupling	5/988	16/18722	0.00108583109658952	0.00886422489322996	CAV1/PDE4D/CALM1/GJA1/GJA5	5
GO:0033631	cell-cell adhesion mediated by integrin	5/988	16/18722	0.00108583109658952	0.00886422489322996	PODXL/PIEZO1/ITGB1/PLPP3/WNK1	5
GO:0071361	cellular response to ethanol	5/988	16/18722	0.00108583109658952	0.00886422489322996	PRKCE/TP53INP1/PTEN/ITPR2/PRKAA1	5
GO:0072109	glomerular mesangium development	5/988	16/18722	0.00108583109658952	0.00886422489322996	CD34/NOTCH1/PDGFB/CFLAR/EGR1	5
GO:1901201	regulation of extracellular matrix assembly	5/988	16/18722	0.00108583109658952	0.00886422489322996	TIE1/NOTCH1/RGCC/PHLDB2/TGFB1	5
GO:0031663	lipopolysaccharide-mediated signaling pathway	10/988	60/18722	0.00108800350722627	0.00886422489322996	SCARB1/PRKCE/MTDH/SASH1/CARD16/TGFB1/CARD8/CD36/MAPK1/BCL10	10
GO:1903670	regulation of sprouting angiogenesis	10/988	60/18722	0.00108800350722627	0.00886422489322996	RHOJ/CEACAM1/ITGA5/KLF2/TJP1/THBS1/SMAD1/JAK1/KLF4/SYNJ2BP	10
GO:0050870	positive regulation of T cell activation	23/988	216/18722	0.00109620548210877	0.00891737139504102	IGF1/HLX/CAV1/HLA-E/HLA-A/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/FYN/PIK3CA/TNFRSF14/RHOA/ZMIZ1/CD46/HES1/HSPH1/BCL10	23
GO:0030041	actin filament polymerization	21/988	190/18722	0.00110537172178456	0.00897818744054978	SPTBN1/ESAM/KANK3/CDC42EP5/PRKCE/SPTAN1/TMSB4X/ARHGAP28/NCKAP1/TMSB10/TMOD3/RDX/ACTR2/RHOA/ABI2/CTTN/MYO1C/ADD1/GSN/WASL/TTC17	21
GO:0048661	positive regulation of smooth muscle cell proliferation	14/988	104/18722	0.00111931162064906	0.00906369409891432	EDN1/CALCRL/IGF1/S1PR1/ITGA2/FOXP1/THBS1/TGFBR2/PDGFB/GNAI2/TGFB1/GJA1/ID2/JUN	14
GO:1903076	regulation of protein localization to plasma membrane	14/988	104/18722	0.00111931162064906	0.00906369409891432	SPTBN1/RAMP3/PRKCE/PPP2R5A/ITGB1/KIF5B/PRKCH/TGFB1/STX3/ACSL3/ATP2B4/PICALM/HECTD1/RAB11A	14
GO:0050768	negative regulation of neurogenesis	17/988	140/18722	0.00114116848047807	0.00922661639010575	ID1/NOTCH1/B2M/NRP1/DICER1/PTEN/GDI1/SKI/PCM1/SEMA3F/RTN4/RAPGEF2/CTNNA1/RUFY3/PPP3CA/CTDSP1/HES1	17
GO:0018107	peptidyl-threonine phosphorylation	15/988	116/18722	0.00115096955042101	0.00927761798457727	CDC42BPA/TGFBR2/HIPK2/APP/PKN1/CALM1/TGFB1/HIPK3/HIPK1/WNK1/CDC42BPB/ROCK2/DYRK1A/ROCK1/MAPK1	15
GO:0021782	glial cell development	15/988	116/18722	0.00115096955042101	0.00927761798457727	VIM/ADGRG6/LAMB2/CLU/APP/CDK6/MDK/DICER1/PTEN/SKI/NDRG1/PPP3R1/CD9/PLEC/B4GALT5	15
GO:0008154	actin polymerization or depolymerization	23/988	217/18722	0.001166602839426	0.009376468583351	SPTBN1/ESAM/KANK3/CDC42EP5/PRKCE/SPTAN1/TMSB4X/ARHGAP28/NCKAP1/TMSB10/PIK3CA/TMOD3/RDX/ACTR2/RHOA/ABI2/CTTN/MYO1C/ADD1/GSN/WASL/TTC17/DSTN	23
GO:0051591	response to cAMP	13/988	93/18722	0.00116852827601249	0.009376468583351	SPARC/CRHBP/TEK/THBD/AHR/ZFP36L1/APP/DUSP1/ITPR2/PKD2/RAPGEF2/JUN/RAP1A	13
GO:0106027	neuron projection organization	13/988	93/18722	0.00116852827601249	0.009376468583351	FCGR2B/TANC1/PDLIM5/APP/FYN/PTEN/ACTR2/ABI2/ADAM10/CTTN/DIP2A/WASL/CDC42	13
GO:0014044	Schwann cell development	7/988	32/18722	0.00117546248503062	0.00938955897816944	ADGRG6/LAMB2/DICER1/SKI/NDRG1/PPP3R1/PLEC	7
GO:1901532	regulation of hematopoietic progenitor cell differentiation	7/988	32/18722	0.00117546248503062	0.00938955897816944	TCF15/NOTCH1/N4BP2L2/EIF2AK2/HES1/SOS2/SOS1	7
GO:1901889	negative regulation of cell junction assembly	7/988	32/18722	0.00117546248503062	0.00938955897816944	ACVRL1/DLC1/THBS1/PHLDB2/PTEN/ROCK2/ROCK1	7
GO:0001953	negative regulation of cell-matrix adhesion	8/988	41/18722	0.00117901198051534	0.00938967262443405	ACVRL1/JAG1/ADAM15/DLC1/THBS1/PHLDB2/PTEN/MAP4K4	8
GO:1905521	regulation of macrophage migration	8/988	41/18722	0.00117901198051534	0.00938967262443405	MTUS1/THBS1/CD81/MDK/CD200/CD9/PTK2/MAPK1	8
GO:2001057	reactive nitrogen species metabolic process	12/988	82/18722	0.00118931581454618	0.0094575533036966	CD34/EDN1/CAV1/KLF2/CLU/DDAH2/KLF4/CD36/PKD2/ATP2B4/ROCK2/CYB5R3	12
GO:0045165	cell fate commitment	26/988	258/18722	0.00121736204407418	0.00966610938433788	SOX18/HOXA13/ZNF521/NOTCH4/MEF2C/JAG1/EPAS1/NOTCH1/ITGB1/SMAD5/SMAD1/NRP1/PML/KLF4/RHOA/STAT3/GATA2/NR2F2/TBX3/APC/SMAD2/ETS2/HES1/CDC42/ID2/SMAD4	26
GO:0034341	response to interferon-gamma	17/988	141/18722	0.00123537465503978	0.00970436660707538	VIM/BST2/EDN1/GBP4/IFITM2/IFITM3/IFITM1/FLNB/KIF5B/JAK1/PARP14/ACTR2/PARP9/MYO1C/SP100/CDC42/SEC61A1	17
GO:0035296	regulation of tube diameter	17/988	141/18722	0.00123537465503978	0.00970436660707538	EDN1/ECE1/P2RY1/F2R/NPR1/CAV1/BMPR2/ITGA1/KLF2/DOCK4/ADRB1/GJA1/RHOA/PIK3C2A/GJA5/ROCK2/ROCK1	17
GO:0097746	blood vessel diameter maintenance	17/988	141/18722	0.00123537465503978	0.00970436660707538	EDN1/ECE1/P2RY1/F2R/NPR1/CAV1/BMPR2/ITGA1/KLF2/DOCK4/ADRB1/GJA1/RHOA/PIK3C2A/GJA5/ROCK2/ROCK1	17
GO:0003183	mitral valve morphogenesis	4/988	10/18722	0.00125283891899623	0.00970436660707538	DCHS1/SMAD6/BMPR2/NOTCH1	4
GO:0050861	positive regulation of B cell receptor signaling pathway	4/988	10/18722	0.00125283891899623	0.00970436660707538	FOXP1/CD81/PRKCH/CMTM3	4
GO:0090647	modulation of age-related behavioral decline	4/988	10/18722	0.00125283891899623	0.00970436660707538	B2M/APP/BAZ2B/PICALM	4
GO:0097084	vascular associated smooth muscle cell development	4/988	10/18722	0.00125283891899623	0.00970436660707538	RAMP2/ENG/NOTCH1/HES1	4
GO:1905456	regulation of lymphoid progenitor cell differentiation	4/988	10/18722	0.00125283891899623	0.00970436660707538	NOTCH1/HES1/SOS2/SOS1	4
GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	4/988	10/18722	0.00125283891899623	0.00970436660707538	NOTCH4/PPM1F/NOTCH1/RGCC	4
GO:0060348	bone development	22/988	205/18722	0.001256786544246	0.00970436660707538	IGF1/TEK/FLI1/PLS3/DCHS1/MEF2C/ENG/BMPR2/FOXP1/SH2B3/TGFBR2/SMAD5/SMAD1/SULF2/CHSY1/GJA1/SERPINH1/RHOA/SKI/LTBP3/FOXN3/ZMPSTE24	22
GO:0045668	negative regulation of osteoblast differentiation	9/988	51/18722	0.00125725162702711	0.00970436660707538	VEGFC/SMAD6/ID3/HDAC7/NOTCH1/CRIM1/CDK6/SKI/NBR1	9
GO:0048013	ephrin receptor signaling pathway	9/988	51/18722	0.00125725162702711	0.00970436660707538	EFNB2/GIT1/ANKS1A/YES1/EFNB1/FYN/ARHGEF7/CRK/PTK2	9
GO:0072676	lymphocyte migration	15/988	117/18722	0.00125730159155328	0.00970436660707538	JAM2/S1PR1/MSN/APP/SLC12A2/CD200/TNFRSF14/RHOA/ADAM10/LRCH1/F11R/CRK/PLEC/WNK1/WASL	15
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	6/988	24/18722	0.00126054460822327	0.00970436660707538	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/CRK	6
GO:0003148	outflow tract septum morphogenesis	6/988	24/18722	0.00126054460822327	0.00970436660707538	SMAD6/ENG/BMPR2/TGFBR2/NRP1/SMAD4	6
GO:0003181	atrioventricular valve morphogenesis	6/988	24/18722	0.00126054460822327	0.00970436660707538	DCHS1/SMAD6/BMPR2/NOTCH1/TGFBR2/SMAD4	6
GO:0030859	polarized epithelial cell differentiation	6/988	24/18722	0.00126054460822327	0.00970436660707538	TCF15/FOXF1/MSN/RHOA/MYO9A/CDC42	6
GO:0036010	protein localization to endosome	6/988	24/18722	0.00126054460822327	0.00970436660707538	MSN/NRP1/AKAP11/RDX/DTX3L/ROCK2	6
GO:0044321	response to leptin	6/988	24/18722	0.00126054460822327	0.00970436660707538	EDN1/LEPR/UGCG/PTEN/STAT3/CCND1	6
GO:0060479	lung cell differentiation	6/988	24/18722	0.00126054460822327	0.00970436660707538	NFIB/THRA/KLF2/CREB1/PPP3R1/SAV1	6
GO:0072010	glomerular epithelium development	6/988	24/18722	0.00126054460822327	0.00970436660707538	PECAM1/CD34/PODXL/JAG1/LAMB2/IQGAP1	6
GO:0035150	regulation of tube size	17/988	142/18722	0.00133608608004316	0.0102710408931827	EDN1/ECE1/P2RY1/F2R/NPR1/CAV1/BMPR2/ITGA1/KLF2/DOCK4/ADRB1/GJA1/RHOA/PIK3C2A/GJA5/ROCK2/ROCK1	17
GO:0048863	stem cell differentiation	22/988	206/18722	0.00133883981195431	0.0102773368224007	A2M/EDN1/LRP6/SOX18/TCF15/MEF2C/FN1/JAG1/NOTCH1/NRP1/EFNB1/N4BP2L2/HIF1A/PHACTR4/STAT3/EIF2AK2/SEMA3F/ZFP36L2/LTBP3/HES1/MAPK1/SMAD4	22
GO:0046620	regulation of organ growth	14/988	106/18722	0.00135009738782914	0.0103487984475446	EDN1/IGF1/HLX/MEF2C/NOTCH1/TGFBR2/IGF2/GJA1/DUSP6/PTEN/WWC2/WWC3/MAPK1/SAV1	14
GO:1903313	positive regulation of mRNA metabolic process	15/988	118/18722	0.00137176974854289	0.0104997707554177	ZFP36L1/PABPC1/ZFP36/TNRC6B/CELF1/CNOT6L/ZC3HAV1/RC3H1/ZFP36L2/CNOT8/ROCK2/TNRC6A/ROCK1/CNOT2/BTG2	15
GO:0045687	positive regulation of glial cell differentiation	8/988	42/18722	0.00139008084204378	0.0105702479199101	NOTCH1/MDK/DICER1/IL6ST/TGFB1/TNFRSF1B/HES1/ID2	8
GO:0045773	positive regulation of axon extension	8/988	42/18722	0.00139008084204378	0.0105702479199101	FN1/BMPR2/MACF1/NRP1/GDI1/RUFY3/RAB11A/EIF4G2	8
GO:2000404	regulation of T cell migration	8/988	42/18722	0.00139008084204378	0.0105702479199101	APP/CD200/TNFRSF14/RHOA/ADAM10/LRCH1/CRK/WNK1	8
GO:0006606	protein import into nucleus	18/988	155/18722	0.00139092682530444	0.0105702479199101	HYAL2/TXNIP/ANGPT1/NOTCH1/PKIG/MDFIC/IPO11/PML/TGFB1/KPNA3/FLNA/CD36/RANBP2/STAT3/PPP3R1/PPP3CA/CBLB/MAPK1	18
GO:1903364	positive regulation of cellular protein catabolic process	18/988	155/18722	0.00139092682530444	0.0105702479199101	CAV1/MSN/CLU/RNF144B/CD81/TRIB2/ATXN3/PTEN/RNF19A/RDX/CSNK1A1/HECTD1/SOCS4/PTK2/HSPA1A/PIAS1/PLK2/TMTC3	18
GO:1903311	regulation of mRNA metabolic process	28/988	288/18722	0.00139355365301342	0.010575081435439	VIM/NOVA2/ZFP36L1/DDX17/PABPC1/MBNL1/QKI/ZFP36/TNRC6B/CELF1/CNOT6L/SON/MBNL2/ZC3HAV1/RC3H1/ZFP36L2/RBM5/CNOT8/PUM2/ROCK2/TNRC6A/DYRK1A/ROCK1/CNOT2/HNRNPK/BTG2/TIA1/CCNT1	28
GO:0046847	filopodium assembly	10/988	62/18722	0.00141085361277387	0.0106758609559185	FSCN1/FGD5/AGRN/FGD4/NRP1/MYO10/RALA/WASL/CDC42/RAB5A	10
GO:1903078	positive regulation of protein localization to plasma membrane	10/988	62/18722	0.00141085361277387	0.0106758609559185	SPTBN1/RAMP3/PRKCE/ITGB1/KIF5B/PRKCH/STX3/ACSL3/ATP2B4/RAB11A	10
GO:0002431	Fc receptor mediated stimulatory signaling pathway	7/988	33/18722	0.00142487037126496	0.0107145723607964	FCGR2B/PRKCE/YES1/FYN/PLSCR1/PTK2/RAP1A	7
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	7/988	33/18722	0.00142487037126496	0.0107145723607964	MMRN2/VEGFC/FZD4/HHEX/ITGA5/HIF1A/NEDD4	7
GO:0045920	negative regulation of exocytosis	7/988	33/18722	0.00142487037126496	0.0107145723607964	FCGR2B/STXBP6/CEACAM1/FOXF1/NOTCH1/GNAI2/RAP1A	7
GO:0008593	regulation of Notch signaling pathway	13/988	95/18722	0.00142605471744786	0.0107145723607964	EGFL7/JAG1/TSPAN14/NOTCH1/MFNG/IL6ST/STAT3/ADAM10/GATA2/ZMIZ1/CD46/HES1/SYNJ2BP	13
GO:0030516	regulation of axon extension	13/988	95/18722	0.00142605471744786	0.0107145723607964	FN1/BMPR2/MACF1/NRP1/TTL/DPYSL2/GDI1/SEMA3F/RTN4/CTTN/RUFY3/RAB11A/EIF4G2	13
GO:0030514	negative regulation of BMP signaling pathway	9/988	52/18722	0.00145042529634047	0.0108516326396628	SMAD6/NOTCH1/SKIL/SMURF2/CRIM1/HIPK2/SKI/HTRA1/CTDSPL2	9
GO:0035196	production of miRNAs involved in gene silencing by miRNA	9/988	52/18722	0.00145042529634047	0.0108516326396628	SMAD1/DICER1/TGFB1/STAT3/ADAR/PPP3CA/SMAD2/PUM2/ZMPSTE24	9
GO:0060147	regulation of posttranscriptional gene silencing	9/988	52/18722	0.00145042529634047	0.0108516326396628	TGFB1/ZFP36/STAT3/TNRC6B/ADAR/PPP3CA/PUM2/DDX6/ZMPSTE24	9
GO:0016264	gap junction assembly	5/988	17/18722	0.00147191807675258	0.0109424816772936	APLNR/CAV1/GJA1/CTNNA1/GJA5	5
GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway	5/988	17/18722	0.00147191807675258	0.0109424816772936	LEPROTL1/TMEM50B/LEPROT/TMEM50A/VPS36	5
GO:0033623	regulation of integrin activation	5/988	17/18722	0.00147191807675258	0.0109424816772936	SELP/RASIP1/PIEZO1/JAM3/FERMT2	5
GO:0010921	regulation of phosphatase activity	12/988	84/18722	0.00147308975231237	0.0109424816772936	NUAK1/ITGA2/MEF2C/FKBP1A/ITGA1/RCAN1/GNAI2/CALM1/HSP90B1/ROCK2/ROCK1/PPP1R12A	12
GO:0097061	dendritic spine organization	12/988	84/18722	0.00147308975231237	0.0109424816772936	FCGR2B/TANC1/PDLIM5/FYN/PTEN/ACTR2/ABI2/ADAM10/CTTN/DIP2A/WASL/CDC42	12
GO:0072089	stem cell proliferation	11/988	73/18722	0.0014749278766834	0.0109424816772936	CD34/SOX18/MECOM/VEGFC/ZFP36L1/GJA1/N4BP2L2/FERMT2/EIF2AK2/TBX3/LTBP3	11
GO:0046683	response to organophosphorus	16/988	131/18722	0.00148036966050951	0.0109675364527566	SPARC/CRHBP/TEK/P2RY1/THBD/AHR/ZFP36L1/APP/DUSP1/PTEN/ITPR2/HSP90B1/PKD2/RAPGEF2/JUN/RAP1A	16
GO:0035051	cardiocyte differentiation	18/988	156/18722	0.00149677927660462	0.0110736650659105	EDN1/IGF1/SOX18/SORBS2/EFNB2/MEF2C/JAG1/NOTCH1/ITGB1/MEF2A/PDLIM5/TGFB1/TBX3/PLEC/HES1/MAPK1/SMAD4/ZMPSTE24	18
GO:1901655	cellular response to ketone	13/988	96/18722	0.00157149987970776	0.0116103023101636	FOXO1/MSN/ADAM15/PRKCE/KLF2/AHR/GNB1/CFLAR/KLF4/PRKAA1/NR3C1/ROCK2/XRN1	13
GO:0032878	regulation of establishment or maintenance of cell polarity	6/988	25/18722	0.00158537751620093	0.0116641625568689	CDH5/TEK/RUFY3/GSN/ROCK2/ROCK1	6
GO:0033622	integrin activation	6/988	25/18722	0.00158537751620093	0.0116641625568689	SELP/RASIP1/FN1/PIEZO1/JAM3/FERMT2	6
GO:1903055	positive regulation of extracellular matrix organization	6/988	25/18722	0.00158537751620093	0.0116641625568689	FSCN1/RGCC/PHLDB2/RB1/TGFB1/CFLAR	6
GO:0001947	heart looping	10/988	63/18722	0.00159925014503289	0.0117337248210148	APLNR/SOX18/MEF2C/ENG/NOTCH1/TGFBR2/MIB1/HIF1A/PKD2/TBX3	10
GO:0002704	negative regulation of leukocyte mediated immunity	10/988	63/18722	0.00159925014503289	0.0117337248210148	FCGR2B/BST2/CEACAM1/FOXF1/HLA-E/HLA-A/AHR/HLA-B/CRK/CD46	10
GO:0043588	skin development	26/988	263/18722	0.00160236383699494	0.0117380083223127	LDB2/SOX18/COL3A1/CD109/TCF15/ITGA2/JAG1/TXNIP/NOTCH1/UGCG/ZFP36L1/FLNB/PRKCH/PALLD/ITGA6/ZFP36/CLIC4/FZD6/ASH1L/PLEC/ROCK2/ROCK1/SOS1/SMAD4/SAV1/ZMPSTE24	26
GO:0018205	peptidyl-lysine modification	34/988	376/18722	0.00160425339646065	0.0117380083223127	NNMT/MECOM/NNAT/LOXL2/HDAC7/PCGF2/BCOR/KMT2E/PML/ATRX/KMT2A/PLOD2/MSL1/RANBP2/OGT/GATA2/ZMIZ1/EGR1/SENP7/ASH1L/CLOCK/WDR82/EID1/PRKAA1/KAT6A/DIP2A/ATF2/KMT5B/RIF1/PIAS1/SMAD4/SENP6/ZMPSTE24/KANSL1	34
GO:0051897	positive regulation of protein kinase B signaling	15/988	120/18722	0.00162705427042059	0.0118884625646137	TEK/RAMP3/ENG/FGFR1/HIP1/THBS1/ANGPT1/IGF2/ITGB1/MTDH/TGFB1/PIK3CA/FERMT2/RTN4/PTK2	15
GO:0002819	regulation of adaptive immune response	20/988	183/18722	0.00164439530932253	0.0119986646746172	FCGR2B/HLX/CEACAM1/MEF2C/IL1R1/HLA-E/HLA-A/AHR/HLA-B/B2M/CD81/PKN1/IL6ST/TGFB1/TNFRSF14/RC3H1/TNFRSF1B/CD46/KMT5B/RIF1	20
GO:0060966	regulation of gene silencing by RNA	9/988	53/18722	0.00166675027072666	0.0121284622439726	TGFB1/ZFP36/STAT3/TNRC6B/ADAR/PPP3CA/PUM2/DDX6/ZMPSTE24	9
GO:1990090	cellular response to nerve growth factor stimulus	9/988	53/18722	0.00166675027072666	0.0121284622439726	ID1/APP/PTEN/CREB1/ACAP2/RAPGEF2/CRK/BPTF/RAP1A	9
GO:0010959	regulation of metal ion transport	36/988	406/18722	0.00167169676083014	0.0121478155862239	APLNR/RAMP3/F2R/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/ITGB1/B2M/UTRN/KIF5B/PDGFB/STOM/ACTN4/GNAI2/SARAF/CALM1/PML/GJA1/FYN/SESTD1/STIM2/PTEN/PDE4B/FLNA/RHOA/TMBIM6/AHNAK/SLC30A1/PKD2/FXYD5/ATP2B4/CRBN/WNK1/NEDD4	36
GO:0002274	myeloid leukocyte activation	23/988	223/18722	0.00167614322965863	0.0121634874808014	CD93/FCGR2B/IL33/ADGRF5/FOXF1/HYAL2/FOXP1/SYT11/PRKCE/THBS1/TGFBR2/CLU/KMT2E/APP/CD200/DYSF/NDRG1/ADAM10/GATA2/PLSCR1/SNAP23/PJA2/S100A13	23
GO:0051961	negative regulation of nervous system development	17/988	145/18722	0.00168083465839528	0.0121642966013566	ID1/NOTCH1/B2M/NRP1/DICER1/PTEN/GDI1/SKI/PCM1/SEMA3F/RTN4/RAPGEF2/CTNNA1/RUFY3/PPP3CA/CTDSP1/HES1	17
GO:0061351	neural precursor cell proliferation	17/988	145/18722	0.00168083465839528	0.0121642966013566	VEGFC/LIMS2/ZNF503/DIXDC1/NOTCH1/MDK/GNAI2/FLNA/RHOA/HIF1A/GATA2/PCM1/FZD6/CTNNA1/ID2/BTG2/SLC16A2	17
GO:0043276	anoikis	7/988	34/18722	0.00171370137312472	0.0123579660366325	ITGA5/CAV1/NOTCH1/ITGB1/PDK4/PIK3CA/PTK2	7
GO:2000352	negative regulation of endothelial cell apoptotic process	7/988	34/18722	0.00171370137312472	0.0123579660366325	CDH5/RAMP2/KDR/TEK/NDNF/ANGPT1/GATA2	7
GO:0045637	regulation of myeloid cell differentiation	22/988	210/18722	0.0017145747306096	0.0123579660366325	CEACAM1/MEF2C/JAG1/FOXP1/ETS1/B2M/ZFP36L1/RB1/CDK6/TGFB1/GABPA/ISG15/HIF1A/ZFP36/CREB1/STAT3/GATA2/KLF10/PURB/HSPA1A/ID2/JUN	22
GO:0120162	positive regulation of cold-induced thermogenesis	13/988	97/18722	0.00172902178052531	0.0124115725650682	FABP4/LEPR/CAV1/EPAS1/THRA/FABP5/ADRB1/GJA1/CD36/PLAC8/OGT/APC/DYNC1H1	13
GO:1901216	positive regulation of neuron death	13/988	97/18722	0.00172902178052531	0.0124115725650682	FCGR2B/EFNB2/ITGA1/CLU/FYN/MAP3K11/CAPN2/RHOA/EGR1/PICALM/ATF2/CDC42/JUN	13
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	13/988	97/18722	0.00172902178052531	0.0124115725650682	IGF1/THBS1/NRP1/PEA15/CFLAR/FYN/ZMYND11/ITGA6/RB1CC1/CTTN/CTNNA1/PHIP/HSPA1A	13
GO:0010952	positive regulation of peptidase activity	21/988	197/18722	0.00174210027897227	0.0124885785180846	SOX7/F2R/UACA/TNFSF10/FN1/CAV1/HIP1/DLC1/PPM1F/IFI16/APP/PML/CFLAR/FYN/CARD8/RHOA/STAT3/PICALM/GSN/ROCK2/BCL10	21
GO:0001704	formation of primary germ layer	15/988	121/18722	0.00176888632042603	0.0126366029037878	SOX7/FOXF1/ITGA2/FN1/ITGA5/BMPR2/COL4A2/ITGB1/SMAD1/DUSP1/GJA1/PRKAR1A/KLF4/SMAD2/ETS2	15
GO:0072594	establishment of protein localization to organelle	37/988	422/18722	0.00176890483966386	0.0126366029037878	ABLIM3/HYAL2/TXNIP/ANGPT1/NOTCH1/CLU/PKIG/MDFIC/SCARB2/SPCS3/IPO11/CALM1/PML/TGFB1/TRAM1/KPNA3/LAMP1/SEC62/FLNA/CD36/RANBP2/STAT3/MAN1A1/VPS13C/PPP3R1/PPP3CA/LEPROT/CBLB/PRKAA1/NIPBL/RALA/SH3GLB1/RAB11A/MAPK1/NEDD4/SEC61A1/VPS36	37
GO:0002456	T cell mediated immunity	14/988	109/18722	0.00176988564766908	0.0126366029037878	FCGR2B/CEACAM1/JAG1/IL1R1/HLA-E/HLA-A/AHR/HLA-B/B2M/CD81/RAB27A/EMP2/TNFRSF1B/CD46	14
GO:0046579	positive regulation of Ras protein signal transduction	10/988	64/18722	0.00180752562967928	0.0128880216709481	IGF1/COL3A1/F2R/LPAR6/NOTCH1/MAP4K4/ARPP19/F11R/SHOC2/ARHGEF3	10
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	17/988	146/18722	0.00181121372629939	0.0128970071234616	RAMP2/CALCRL/ADGRL4/ADGRL2/S1PR1/RAMP3/ADCY4/ADGRG6/PDE4D/GNAI2/ADRB1/GNAQ/GNB1/PDE4B/ABCA1/RAPGEF2/ATP2B4	17
GO:0051346	negative regulation of hydrolase activity	34/988	379/18722	0.00183014683666958	0.0130143775052059	A2M/BST2/LEPR/CD109/BICD1/PROS1/TFPI2/RASA4/TFPI/FKBP1A/THBS1/IFI16/RPS6KA3/TIMP1/CRIM1/CARD16/APP/XIAP/GNAI2/CARD8/KLF4/SERPINH1/CNN3/EGLN1/RDX/TMBIM6/LRCH1/PICALM/CD44/PAK2/F11R/WNK1/ROCK2/ROCK1	34
GO:0045913	positive regulation of carbohydrate metabolic process	11/988	75/18722	0.00184502515534004	0.0131026385363186	IGF1/NNMT/P2RY1/ZBTB20/PRKCE/IGF2/PDGFB/APP/HIF1A/ARPP19/PRKAA1	11
GO:0051170	import into nucleus	18/988	159/18722	0.00185612499679485	0.0131638664659202	HYAL2/TXNIP/ANGPT1/NOTCH1/PKIG/MDFIC/IPO11/PML/TGFB1/KPNA3/FLNA/CD36/RANBP2/STAT3/PPP3R1/PPP3CA/CBLB/MAPK1	18
GO:0007369	gastrulation	20/988	185/18722	0.00187375208604803	0.0132055217995247	APLNR/SOX7/FOXF1/ITGA2/FN1/ITGA5/BMPR2/COL4A2/TGFBR2/ITGB1/PHLDB2/SMAD1/DUSP1/GJA1/PRKAR1A/KLF4/SMAD2/WNK1/ETS2/SMAD4	20
GO:0051896	regulation of protein kinase B signaling	20/988	185/18722	0.00187375208604803	0.0132055217995247	TEK/RAMP3/HYAL2/ENG/FGFR1/HIP1/THBS1/ANGPT1/SH2B3/IGF2/ITGB1/MTDH/TGFB1/PIK3CA/KLF4/PTEN/RRAS/FERMT2/RTN4/PTK2	20
GO:0008277	regulation of G protein-coupled receptor signaling pathway	16/988	134/18722	0.00187760861277354	0.0132055217995247	APLNR/RAMP2/EDN1/RGS5/RAMP3/BICD1/RGS3/PLCB1/GIT1/GNAI2/PDE4B/ATP2B4/GIT2/ROCK2/ROCK1/YWHAB	16
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	16/988	134/18722	0.00187760861277354	0.0132055217995247	CAV1/CLU/RNF144B/TRIB2/RNF19A/OGT/RYBP/SDCBP/CSNK1A1/HECTD1/SOCS4/WAC/HSPA1A/XPO1/PIAS1/PLK2	16
GO:0050670	regulation of lymphocyte proliferation	23/988	225/18722	0.00188364571792369	0.0132055217995247	FCGR2B/IGF1/LRRC32/MEF2C/HLA-E/HLA-A/AHR/TGFBR2/IGF2/CD81/PKN1/EFNB1/IL6ST/PRKAR1A/TNFRSF14/RC3H1/TNFRSF1B/CBLB/CD320/CD46/HES1/SOS2/SOS1	23
GO:0034975	protein folding in endoplasmic reticulum	4/988	11/18722	0.0018868582541113	0.0132055217995247	CANX/DNAJC10/ERO1A/HSP90B1	4
GO:0045793	positive regulation of cell size	4/988	11/18722	0.0018868582541113	0.0132055217995247	EDN1/TMEM123/AKT3/RB1CC1	4
GO:0099022	vesicle tethering	4/988	11/18722	0.0018868582541113	0.0132055217995247	EXOC6/WDR11/FAM91A1/STARD3NL	4
GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	4/988	11/18722	0.0018868582541113	0.0132055217995247	TCF15/NOTCH1/N4BP2L2/HES1	4
GO:1905668	positive regulation of protein localization to endosome	4/988	11/18722	0.0018868582541113	0.0132055217995247	MSN/RDX/DTX3L/ROCK2	4
GO:0031295	T cell costimulation	8/988	44/18722	0.0019016963326766	0.0132672918274843	CAV1/CD81/LGALS1/YES1/EFNB1/FYN/PIK3CA/TNFRSF14	8
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	8/988	44/18722	0.0019016963326766	0.0132672918274843	TCF15/FOXF1/MSN/RHOA/MYO9A/PDCD6IP/CDC42/SYNJ2BP	8
GO:0031050	dsRNA processing	9/988	54/18722	0.00190817224326017	0.0132672918274843	SMAD1/DICER1/TGFB1/STAT3/ADAR/PPP3CA/SMAD2/PUM2/ZMPSTE24	9
GO:0070918	production of small RNA involved in gene silencing by RNA	9/988	54/18722	0.00190817224326017	0.0132672918274843	SMAD1/DICER1/TGFB1/STAT3/ADAR/PPP3CA/SMAD2/PUM2/ZMPSTE24	9
GO:1902743	regulation of lamellipodium organization	9/988	54/18722	0.00190817224326017	0.0132672918274843	FSCN1/ENPP2/NCKAP1/PIK3CA/ACTR2/ABI2/CD44/ARHGEF7/CDC42	9
GO:0006939	smooth muscle contraction	14/988	110/18722	0.00193186123031098	0.0134144403338718	EDN1/CALCRL/ITGA2/F2R/CAV1/DOCK4/SULF2/RHOA/PIK3C2A/CTTN/TBX3/ATP2B4/ROCK2/ROCK1	14
GO:0060041	retina development in camera-type eye	17/988	147/18722	0.00194998552017982	0.0134368661861755	ACVRL1/RHOJ/FZD4/ARHGEF15/COL4A1/BMPR2/TSPAN12/LAMB2/NRP1/HIPK2/GNB1/HIF1A/SKI/PTPRM/CLIC4/ATP2B4/HIPK1	17
GO:0043116	negative regulation of vascular permeability	5/988	18/18722	0.00195026804019979	0.0134368661861755	RAMP2/CLDN5/CEACAM1/ANGPT1/FERMT2	5
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	5/988	18/18722	0.00195026804019979	0.0134368661861755	CEACAM1/HLA-E/HLA-A/HLA-B/CRK	5
GO:0051895	negative regulation of focal adhesion assembly	5/988	18/18722	0.00195026804019979	0.0134368661861755	ACVRL1/DLC1/THBS1/PHLDB2/PTEN	5
GO:0150118	negative regulation of cell-substrate junction organization	5/988	18/18722	0.00195026804019979	0.0134368661861755	ACVRL1/DLC1/THBS1/PHLDB2/PTEN	5
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	5/988	18/18722	0.00195026804019979	0.0134368661861755	BMPR2/NOTCH1/TBX3/HES1/SMAD4	5
GO:0009743	response to carbohydrate	25/988	253/18722	0.00196229583661573	0.0135022221296668	SPARC/CALCRL/ZBTB20/ITGA2/RPS6KA2/ANGPT2/PRKCE/TXNIP/THBS1/TGFBR2/ZFP36L1/KIF5B/LGALS1/GJA1/PIK3CA/PTEN/RHOA/HIF1A/MAP4K4/EGR1/PPP3CA/PIM3/PRKAA1/SMAD2/RAP1A	25
GO:0033522	histone H2A ubiquitination	6/988	26/18722	0.00197009264194465	0.0135208425245607	PCGF2/BCOR/RYBP/PCGF5/DTX3L/TRIP12	6
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	6/988	26/18722	0.00197009264194465	0.0135208425245607	PDE4D/GNAI2/ADRB1/PDE4B/RAPGEF2/ATP2B4	6
GO:0042098	T cell proliferation	21/988	199/18722	0.00197316222786723	0.0135244358121687	IGF1/LRRC32/MSN/HLA-E/HLA-A/TGFBR2/IGF2/CD81/EFNB1/IL6ST/PRKAR1A/FYN/TNFRSF14/RC3H1/TNFRSF1B/CBLB/CD151/CD46/HES1/SOS2/SOS1	21
GO:0090316	positive regulation of intracellular protein transport	18/988	160/18722	0.00199099140130146	0.0136290545408677	ABLIM3/HYAL2/CD81/KIF5B/STOM/TGFB1/FYN/FLNA/PCM1/MYO1C/RUFY3/LEPROT/PRKAA1/SH3GLB1/CDC42/MAPK1/OAZ2/CTDSPL2	18
GO:0031345	negative regulation of cell projection organization	20/988	186/18722	0.00199823445348484	0.013643472258241	VIM/EFNB2/ID1/B2M/NRP1/LGALS1/FYN/PTEN/GDI1/FLNA/RHOA/MAP4K4/PTPRG/SEMA3F/RTN4/RAPGEF2/RUFY3/THOC2/PPP3CA/MAP4	20
GO:0120032	regulation of plasma membrane bounded cell projection assembly	20/988	186/18722	0.00199823445348484	0.013643472258241	PODXL/FSCN1/CDC42EP5/CAV1/AGRN/NRP1/NCKAP1/PIK3CA/RDX/MYO10/ACTR2/ABI2/CYLD/APC/CCDC88A/RALA/MAP4/WASL/CDC42/RAB5A	20
GO:0060996	dendritic spine development	13/988	99/18722	0.00208332906279942	0.0142062182048659	MEF2C/PDLIM5/PTEN/ACTR2/ABI2/ADAM10/PAK2/DIP2A/UBA6/WASL/CDC42/EIF4G2/PLK2	13
GO:0051258	protein polymerization	28/988	296/18722	0.00208828314934532	0.0142217437042594	CDH5/SPTBN1/ESAM/KANK3/CDC42EP5/PRKCE/SPTAN1/TMSB4X/ARHGAP28/GIT1/NCKAP1/TMSB10/TMOD3/RDX/ACTR2/RHOA/ABI2/CTTN/MYO1C/ADD1/ARHGEF7/GSN/WASL/DYRK1A/TTC17/HSPA1A/CAMSAP2/NIN	28
GO:0032944	regulation of mononuclear cell proliferation	23/988	227/18722	0.00211265463401275	0.014369297587549	FCGR2B/IGF1/LRRC32/MEF2C/HLA-E/HLA-A/AHR/TGFBR2/IGF2/CD81/PKN1/EFNB1/IL6ST/PRKAR1A/TNFRSF14/RC3H1/TNFRSF1B/CBLB/CD320/CD46/HES1/SOS2/SOS1	23
GO:0002697	regulation of immune effector process	31/988	339/18722	0.00211983617655174	0.0143997055880343	A2M/FCGR2B/BST2/HLX/CEACAM1/FOXF1/IL1R1/HLA-E/HLA-A/AHR/ANGPT1/HLA-B/B2M/CD81/DDX60/PKN1/TGFB1/LAMP1/TNFRSF14/CD59/CD36/TMBIM6/GATA2/RC3H1/TNFRSF1B/CRK/CD46/KMT5B/RIF1/BCL10/RAP1A	31
GO:0003229	ventricular cardiac muscle tissue development	9/988	55/18722	0.00217671794888039	0.0147483746740467	HEG1/ENG/FKBP1A/NOTCH1/TGFB1/TBX3/ID2/SMAD4/ZMPSTE24	9
GO:0044091	membrane biogenesis	9/988	55/18722	0.00217671794888039	0.0147483746740467	SPTBN1/CAV1/CAV2/SYT11/UGCG/SERINC1/PTEN/EMP2/PICALM	9
GO:1903362	regulation of cellular protein catabolic process	25/988	255/18722	0.00218409011619983	0.014779473499686	CAV1/MSN/CLU/RNF144B/CD81/HIPK2/PML/TRIB2/ATXN3/PTEN/RNF19A/RDX/OGT/RYBP/SDCBP/CSNK1A1/HECTD1/SOCS4/WAC/PTK2/HSPA1A/XPO1/PIAS1/PLK2/TMTC3	25
GO:0006110	regulation of glycolytic process	8/988	45/18722	0.002207757085554	0.0149206178606397	IGF1/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	8
GO:0060491	regulation of cell projection assembly	20/988	188/18722	0.00226826610728268	0.0153100756821926	PODXL/FSCN1/CDC42EP5/CAV1/AGRN/NRP1/NCKAP1/PIK3CA/RDX/MYO10/ACTR2/ABI2/CYLD/APC/CCDC88A/RALA/MAP4/WASL/CDC42/RAB5A	20
GO:0051100	negative regulation of binding	18/988	162/18722	0.00228554647324559	0.0153972529658861	P2RY1/CAV1/ADAM15/ID1/IFI16/TMSB4X/ARHGAP28/B2M/PDGFB/CARD16/TMBIM6/RALB/IFIT2/RSF1/PPP3CA/SP100/ROCK1/JUN	18
GO:0007492	endoderm development	11/988	77/18722	0.00228745033397409	0.0153972529658861	SOX7/FN1/ITGA5/COL4A2/NOTCH1/ZFP36L1/LAMC1/DUSP1/SMAD2/BPTF/SMAD4	11
GO:0000956	nuclear-transcribed mRNA catabolic process	14/988	112/18722	0.00229277618524395	0.0153972529658861	ZFP36L1/PABPC1/ZFP36/CSDE1/TNRC6B/CNOT6L/RC3H1/ZFP36L2/CNOT8/SMG1/TNRC6A/CNOT2/XRN1/BTG2	14
GO:1901222	regulation of NIK/NF-kappaB signaling	14/988	112/18722	0.00229277618524395	0.0153972529658861	EDN1/UACA/HDAC7/TMSB4X/ACTN4/SASH1/APP/TSPAN6/LIMS1/NFAT5/RHOA/CYLD/EIF2AK2/RC3H1	14
GO:0030879	mammary gland development	16/988	137/18722	0.00236034380320421	0.0158309927810869	NOTCH4/FOXF1/ITGA2/CAV1/PAM/TGFBR2/PML/OAS2/HIF1A/CREB1/RTN4/TBX3/ARHGAP5/CCND1/MAPK1/ID2	16
GO:0071695	anatomical structure maturation	23/988	229/18722	0.00236491411788778	0.0158416441289027	CDH5/IGF1/ACVRL1/SOX18/S1PR1/DCHS1/SCARF1/RPS6KA2/AGRN/EPAS1/KLF2/APP/ANKS1A/RB1/CDC25B/LYL1/RHOA/HIF1A/GATA2/FEM1B/PTBP3/HES1/B4GALT5	23
GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	6/988	27/18722	0.00242138840465688	0.0161588130722831	FCGR2B/PRKCE/YES1/FYN/PTK2/RAP1A	6
GO:0032967	positive regulation of collagen biosynthetic process	6/988	27/18722	0.00242138840465688	0.0161588130722831	VIM/ITGA2/F2R/ENG/RGCC/TGFB1	6
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	6/988	27/18722	0.00242138840465688	0.0161588130722831	FCGR2B/PRKCE/YES1/FYN/PTK2/RAP1A	6
GO:0010762	regulation of fibroblast migration	7/988	36/18722	0.00242602641424589	0.0161694508312098	HYAL2/PRKCE/THBS1/ITGB1/TGFB1/ARHGEF7/PTK2	7
GO:0043388	positive regulation of DNA binding	9/988	56/18722	0.00247449227159071	0.0164306286833623	IGF1/ITGA2/HIPK2/RB1/CALM1/TGFB1/KLF4/SKI/HES1	9
GO:0043470	regulation of carbohydrate catabolic process	9/988	56/18722	0.00247449227159071	0.0164306286833623	IGF1/ZBTB20/GIT1/APP/SCARB2/HIF1A/OGT/STAT3/PRKAA1	9
GO:1990089	response to nerve growth factor	9/988	56/18722	0.00247449227159071	0.0164306286833623	ID1/APP/PTEN/CREB1/ACAP2/RAPGEF2/CRK/BPTF/RAP1A	9
GO:1904062	regulation of cation transmembrane transport	32/988	357/18722	0.00248461863649494	0.0164772711573797	APLNR/CRHBP/RAMP3/F2R/MEF2C/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/ITGB1/TMSB4X/UTRN/KIF5B/STOM/ACTN4/APP/CALM1/FYN/SESTD1/STIM2/PTEN/PDE4B/FLNA/AHNAK/SLC30A1/PKD2/FXYD5/ATP2B4/CRBN/WNK1/NEDD4	32
GO:0002716	negative regulation of natural killer cell mediated immunity	5/988	19/18722	0.0025329666021593	0.0166317905941535	CEACAM1/HLA-E/HLA-A/HLA-B/CRK	5
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	5/988	19/18722	0.0025329666021593	0.0166317905941535	AGRN/PLCB1/GNAI2/GNAQ/GNB1	5
GO:0010544	negative regulation of platelet activation	5/988	19/18722	0.0025329666021593	0.0166317905941535	CEACAM1/THBD/SH2B3/PDGFB/CD9	5
GO:0035313	wound healing, spreading of epidermal cells	5/988	19/18722	0.0025329666021593	0.0166317905941535	ACVRL1/ITGA5/PHLDB2/PTEN/FERMT2	5
GO:0045821	positive regulation of glycolytic process	5/988	19/18722	0.0025329666021593	0.0166317905941535	IGF1/ZBTB20/APP/HIF1A/PRKAA1	5
GO:0046782	regulation of viral transcription	5/988	19/18722	0.0025329666021593	0.0166317905941535	IFITM3/MDFIC/ZFP36/RSF1/TRIM13	5
GO:0061323	cell proliferation involved in heart morphogenesis	5/988	19/18722	0.0025329666021593	0.0166317905941535	BMPR2/NOTCH1/TBX3/HES1/SMAD4	5
GO:0070262	peptidyl-serine dephosphorylation	5/988	19/18722	0.0025329666021593	0.0166317905941535	PPM1F/DUSP1/PPP2R2A/PPP2CB/PPP3CA	5
GO:0035050	embryonic heart tube development	11/988	78/18722	0.00253886205780982	0.0166499200630688	APLNR/SOX18/MEF2C/ENG/NOTCH1/TGFBR2/MIB1/HIF1A/PKD2/TBX3/HES1	11
GO:0052547	regulation of peptidase activity	39/988	461/18722	0.00255637152930028	0.0167440759107806	A2M/BST2/SOX7/CD109/PROS1/F2R/UACA/TNFSF10/FN1/CAV1/TFPI2/HIP1/TFPI/DLC1/THBS1/PPM1F/IFI16/RPS6KA3/TIMP1/CRIM1/CARD16/APP/XIAP/PML/CFLAR/FYN/CARD8/KLF4/SERPINH1/RHOA/PSMB8/STAT3/PICALM/CD44/PAK2/GSN/ROCK2/ROCK1/BCL10	39
GO:0009880	embryonic pattern specification	10/988	67/18722	0.00256690644015606	0.0167511142630332	MEOX2/SMAD6/SMAD5/SMAD1/NRP1/EFNB1/SEMA3F/TBX3/SMAD2/SMAD4	10
GO:0061371	determination of heart left/right asymmetry	10/988	67/18722	0.00256690644015606	0.0167511142630332	APLNR/SOX18/MEF2C/ENG/NOTCH1/TGFBR2/MIB1/HIF1A/PKD2/TBX3	10
GO:0070527	platelet aggregation	10/988	67/18722	0.00256690644015606	0.0167511142630332	CEACAM1/FN1/SH2B3/IL6ST/MYH9/FLNA/VCL/CD9/F11R/MYL12A	10
GO:0070374	positive regulation of ERK1 and ERK2 cascade	22/988	217/18722	0.00258904278991533	0.0168748408589328	KDR/IGF1/TEK/RAMP3/P2RY1/F2R/ANGPT1/NOTCH1/NRP1/PDGFB/APP/GNAI2/SHC1/TGFB1/CFLAR/PTEN/CD36/FERMT2/NPTN/RAPGEF2/CD44/RAP1A	22
GO:0030324	lung development	19/988	177/18722	0.00260410615450388	0.0169522204567704	SPARC/NFIB/HEG1/FOXF1/BMPR2/EPAS1/THRA/KLF2/NOTCH1/TGFBR2/CREB1/PPP3R1/LIPA/LTBP3/SMAD2/HES1/CDC42/MAPK1/SAV1	19
GO:0052548	regulation of endopeptidase activity	37/988	432/18722	0.00264191895433154	0.017177323727551	A2M/BST2/SOX7/CD109/PROS1/F2R/UACA/TNFSF10/TFPI2/HIP1/TFPI/DLC1/THBS1/PPM1F/IFI16/RPS6KA3/TIMP1/CRIM1/CARD16/APP/XIAP/PML/CFLAR/FYN/CARD8/KLF4/SERPINH1/RHOA/PSMB8/STAT3/PICALM/CD44/PAK2/GSN/ROCK2/ROCK1/BCL10	37
GO:0002328	pro-B cell differentiation	4/988	12/18722	0.00271278864458638	0.0174670706424762	NOTCH1/HES1/SOS2/SOS1	4
GO:0034086	maintenance of sister chromatid cohesion	4/988	12/18722	0.00271278864458638	0.0174670706424762	RB1/ATRX/SLF2/NIPBL	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	4/988	12/18722	0.00271278864458638	0.0174670706424762	RB1/ATRX/SLF2/NIPBL	4
GO:0042117	monocyte activation	4/988	12/18722	0.00271278864458638	0.0174670706424762	HYAL2/FOXP1/DYSF/ADAM10	4
GO:0061517	macrophage proliferation	4/988	12/18722	0.00271278864458638	0.0174670706424762	IL33/CLU/PTK2/MAPK1	4
GO:0072015	glomerular visceral epithelial cell development	4/988	12/18722	0.00271278864458638	0.0174670706424762	PODXL/JAG1/LAMB2/IQGAP1	4
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	4/988	12/18722	0.00271278864458638	0.0174670706424762	PLXND1/NRP1/PLXNA2/SEMA3F	4
GO:1905666	regulation of protein localization to endosome	4/988	12/18722	0.00271278864458638	0.0174670706424762	MSN/RDX/DTX3L/ROCK2	4
GO:0010522	regulation of calcium ion transport into cytosol	13/988	102/18722	0.00272504839622732	0.0175247664415975	APLNR/RAMP3/F2R/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/CALM1/PML/FYN/TMBIM6/PKD2	13
GO:0045598	regulation of fat cell differentiation	16/988	139/18722	0.00273630996216175	0.0175546842016947	WWTR1/FOXO1/JAG1/CCDC85B/ZFP36L1/ZADH2/TGFB1/TRIB2/FERMT2/ZFP36/CREB1/GATA2/ZFP36L2/HES1/ID2/SAV1	16
GO:0051783	regulation of nuclear division	16/988	139/18722	0.00273630996216175	0.0175546842016947	EDN1/IGF1/HOXA13/RPS6KA2/CAV2/PLCB1/IGF2/RGCC/PDGFB/RB1/DUSP1/PRKAR1A/APC/CDC27/PHIP/CDC42	16
GO:0016570	histone modification	39/988	463/18722	0.00275623894605654	0.0176612078183985	APLNR/NNMT/MECOM/HDAC7/PPM1F/IGF2/PCGF2/BCOR/KMT2E/PKN1/ELK4/ATRX/KMT2A/KDM7A/MSL1/SKI/OGT/RYBP/GATA2/PCGF5/TBL1XR1/ASH1L/CLOCK/WDR82/EID1/PRKAA1/KAT6A/NIPBL/WAC/DTX3L/ATF2/TRIP12/KMT5B/RIF1/JMJD1C/SMAD4/BAZ2A/ZMPSTE24/KANSL1	39
GO:0021915	neural tube development	17/988	152/18722	0.00278476092744451	0.0178224699356449	DCHS1/DLC1/NOTCH1/ZFP36L1/TGFB1/LUZP1/PLXNA2/MIB1/HIF1A/SKI/PHACTR4/PKD2/FZD6/HECTD1/RALA/HES1/BCL10	17
GO:0061756	leukocyte adhesion to vascular endothelial cell	9/988	57/18722	0.00280367493097536	0.0179219268752601	JAM2/SELP/ETS1/ITGB1/MDK/KLF4/NFAT5/RHOA/ROCK1	9
GO:0046651	lymphocyte proliferation	27/988	288/18722	0.00281508529534649	0.0179732368856737	FCGR2B/IGF1/LRRC32/MEF2C/MSN/HLA-E/HLA-A/AHR/TGFBR2/IGF2/CD81/PKN1/EFNB1/IL6ST/PRKAR1A/FYN/TNFRSF14/PURA/RC3H1/TNFRSF1B/CBLB/CD320/CD151/CD46/HES1/SOS2/SOS1	27
GO:0071216	cellular response to biotic stimulus	24/988	246/18722	0.00282133828740587	0.0179915353933973	VIM/FCGR2B/PLSCR4/MEF2C/TFPI/SCARB1/PRKCE/TXNIP/MTDH/GIT1/SASH1/CARD16/TGFB1/CARD8/PDE4B/CAPN2/CD36/RHOA/ZFP36/ABCA1/TNFRSF1B/MAPK1/BCL10/ZMPSTE24	24
GO:0019216	regulation of lipid metabolic process	30/988	331/18722	0.00282906386261562	0.0180191693503767	ADGRF5/TEK/ZBTB20/CEACAM1/PLPP1/CAV1/SCARB1/THRA/PRKCE/FABP5/PPP2R5A/IGFBP7/CD81/PDGFB/PDK4/CPT1A/TGFB1/LPGAT1/ACSL3/CAPN2/ELOVL5/CREB1/EGR1/STARD4/PRKAA1/NR1D2/CDC42/PTK2/ID2/ZMPSTE24	30
GO:0051091	positive regulation of DNA-binding transcription factor activity	25/988	260/18722	0.00283400061329559	0.0180289955183547	EDN1/LRP6/FZD4/CAV1/RGCC/CLU/MTDH/CARD16/HIPK2/APP/PRKCH/CD200/CFLAR/PLPP3/PTEN/CD36/STAT3/EIF2AK2/CLOCK/PPP3CA/TRIM13/ATF2/HSPA1A/BCL10/SAV1	25
GO:0030048	actin filament-based movement	15/988	127/18722	0.00285343037034431	0.0180956280168418	CAV1/PDE4D/ACTN4/LIMCH1/GJA1/MYH9/PIK3CA/PDE4B/FLNA/MYO1C/EMP2/GJA5/GSN/WASL/MYL6	15
GO:0045616	regulation of keratinocyte differentiation	7/988	37/18722	0.0028581008859432	0.0180956280168418	CD109/NOTCH1/ZFP36L1/PRKCH/ZFP36/ROCK2/ROCK1	7
GO:0060428	lung epithelium development	7/988	37/18722	0.0028581008859432	0.0180956280168418	NFIB/THRA/KLF2/CREB1/PPP3R1/CDC42/SAV1	7
GO:0071985	multivesicular body sorting pathway	7/988	37/18722	0.0028581008859432	0.0180956280168418	LEPROTL1/LYST/RAB27A/TMEM50B/LEPROT/TMEM50A/VPS36	7
GO:0032922	circadian regulation of gene expression	10/988	68/18722	0.0028702659529075	0.0181510151688627	ID3/AHR/ID1/PML/KMT2A/OGT/EGR1/CLOCK/ID2/BHLHE40	10
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	8/988	47/18722	0.0029349874506627	0.0184334433457005	EDN1/ECE1/F2R/RPS6KA2/PCSK5/PDE4D/ADRB1/RHOA	8
GO:0010712	regulation of collagen metabolic process	8/988	47/18722	0.0029349874506627	0.0184334433457005	VIM/ITGA2/F2R/ENG/ITGB1/RGCC/TGFB1/RAP1A	8
GO:0014911	positive regulation of smooth muscle cell migration	8/988	47/18722	0.0029349874506627	0.0184334433457005	IGF1/ITGA2/DOCK4/NRP1/PDGFB/MDK/IQGAP1/CRK	8
GO:0045747	positive regulation of Notch signaling pathway	8/988	47/18722	0.0029349874506627	0.0184334433457005	JAG1/TSPAN14/NOTCH1/MFNG/IL6ST/STAT3/ZMIZ1/HES1	8
GO:0051489	regulation of filopodium assembly	8/988	47/18722	0.0029349874506627	0.0184334433457005	FSCN1/AGRN/NRP1/MYO10/RALA/WASL/CDC42/RAB5A	8
GO:0007064	mitotic sister chromatid cohesion	6/988	28/18722	0.00294615839617841	0.0184334433457005	RB1/ATRX/PDS5B/SLF2/POGZ/NIPBL	6
GO:0010714	positive regulation of collagen metabolic process	6/988	28/18722	0.00294615839617841	0.0184334433457005	VIM/ITGA2/F2R/ENG/RGCC/TGFB1	6
GO:0031342	negative regulation of cell killing	6/988	28/18722	0.00294615839617841	0.0184334433457005	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/CRK	6
GO:0038094	Fc-gamma receptor signaling pathway	6/988	28/18722	0.00294615839617841	0.0184334433457005	FCGR2B/PRKCE/YES1/FYN/PTK2/RAP1A	6
GO:0006936	muscle contraction	31/988	347/18722	0.0030243739818396	0.0189005583429788	EDN1/CALCRL/ITGA2/F2R/CAV1/PDE4D/CLIC2/DOCK4/SMAD5/UTRN/SULF2/CALM1/GJA1/PIK3CA/TMOD3/TPM3/PDE4B/FLNA/RHOA/CALD1/PIK3C2A/CTTN/TBX3/ATP2B4/TPM4/GJA5/GSN/ROCK2/ROCK1/MYL6/MYOF	31
GO:0048145	regulation of fibroblast proliferation	11/988	80/18722	0.00310861389879379	0.0194041798241981	IGF1/DACH1/FN1/PDGFB/CDK6/PML/TP53INP1/SKI/CREB1/ZMIZ1/ZMPSTE24	11
GO:0010721	negative regulation of cell development	19/988	180/18722	0.00314552283809428	0.0196115226713108	IGF1/ID1/NOTCH1/B2M/NRP1/ACTN4/DICER1/PTEN/GDI1/SKI/PCM1/SEMA3F/RTN4/RAPGEF2/CTNNA1/RUFY3/PPP3CA/CTDSP1/HES1	19
GO:0016241	regulation of macroautophagy	16/988	141/18722	0.00316059995132359	0.0196593758096381	KDR/SPTLC2/FEZ2/QSOX1/PIK3CA/HIF1A/RALB/ATP6V1A/VPS13C/TRIM13/WAC/SH3GLB1/SMG1/NEDD4/CAPNS1/PAFAH1B2	16
GO:0032355	response to estradiol	16/988	141/18722	0.00316059995132359	0.0196593758096381	RAMP2/CRHBP/RAMP3/ITGA2/TFPI/ETS1/PAM/TXNIP/DUSP1/TGFB1/GJA1/CFLAR/PTEN/STAT3/NR2F2/CCND1	16
GO:2000736	regulation of stem cell differentiation	9/988	58/18722	0.00316651676338129	0.0196731427451245	TCF15/JAG1/NOTCH1/N4BP2L2/STAT3/EIF2AK2/ZFP36L2/LTBP3/HES1	9
GO:1904377	positive regulation of protein localization to cell periphery	10/988	69/18722	0.00320156984630867	0.0198676857752239	SPTBN1/RAMP3/PRKCE/ITGB1/KIF5B/PRKCH/STX3/ACSL3/ATP2B4/RAB11A	10
GO:0032465	regulation of cytokinesis	12/988	92/18722	0.0032205325715454	0.0198958008051584	PKP4/PRKCE/GIT1/CALM1/CDC25B/RHOA/PKN2/KLHL9/SH3GLB1/RAB11A/CDC42/PLK2	12
GO:0003159	morphogenesis of an endothelium	5/988	20/18722	0.00323225887912209	0.0198958008051584	ACVRL1/FOXP1/RHOB/RHOA/STARD13	5
GO:0043984	histone H4-K16 acetylation	5/988	20/18722	0.00323225887912209	0.0198958008051584	KMT2A/MSL1/OGT/ZMPSTE24/KANSL1	5
GO:0061154	endothelial tube morphogenesis	5/988	20/18722	0.00323225887912209	0.0198958008051584	ACVRL1/FOXP1/RHOB/RHOA/STARD13	5
GO:2000479	regulation of cAMP-dependent protein kinase activity	5/988	20/18722	0.00323225887912209	0.0198958008051584	PKIG/PRKAR1A/RAPGEF2/ATP2B4/PRKAR2A	5
GO:0006892	post-Golgi vesicle-mediated transport	13/988	104/18722	0.00323641193734291	0.0198958008051584	SPTBN1/STXBP6/EXOC6/MACF1/VAMP5/EXOC5/ACSL3/LAMP1/SCAMP1/VPS13C/SNAP23/MON2/GOLGA7	13
GO:1901890	positive regulation of cell junction assembly	13/988	104/18722	0.00323641193734291	0.0198958008051584	CLDN5/KDR/TEK/ADGRL2/CAV1/AGRN/PPM1F/NRP1/LIMS1/FERMT2/MAP4K4/IQGAP1/ROCK1	13
GO:0071219	cellular response to molecule of bacterial origin	22/988	221/18722	0.00323980943080987	0.0198958008051584	VIM/FCGR2B/PLSCR4/MEF2C/TFPI/SCARB1/PRKCE/MTDH/GIT1/SASH1/CARD16/TGFB1/CARD8/PDE4B/CAPN2/CD36/RHOA/ZFP36/ABCA1/TNFRSF1B/MAPK1/BCL10	22
GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	22/988	221/18722	0.00323980943080987	0.0198958008051584	CAV1/CLU/RNF144B/HIPK2/PML/TRIB2/ATXN3/PTEN/RNF19A/OGT/RYBP/SDCBP/CSNK1A1/HECTD1/SOCS4/WAC/PTK2/HSPA1A/XPO1/PIAS1/PLK2/TMTC3	22
GO:0032943	mononuclear cell proliferation	27/988	291/18722	0.00324916067693119	0.0199301865079197	FCGR2B/IGF1/LRRC32/MEF2C/MSN/HLA-E/HLA-A/AHR/TGFBR2/IGF2/CD81/PKN1/EFNB1/IL6ST/PRKAR1A/FYN/TNFRSF14/PURA/RC3H1/TNFRSF1B/CBLB/CD320/CD151/CD46/HES1/SOS2/SOS1	27
GO:0007498	mesoderm development	15/988	129/18722	0.00331842217545227	0.0203315554740513	TIE1/TCF15/FOXF1/ITGA2/BMPR2/ITGB1/SMAD1/ZFP36L1/GJA1/PRKAR1A/KLF4/TBX3/SMAD2/ETS2/SMAD4	15
GO:0097696	receptor signaling pathway via STAT	19/988	181/18722	0.00334563135908982	0.0204342705695405	IGF1/F2R/CAV1/NOTCH1/SH2B3/JAK1/SOCS3/IL6ST/TGFB1/FYN/PARP14/STAT3/IFNAR1/PKD2/PARP9/LEPROT/HES1/ARL2BP/PIAS1	19
GO:0010613	positive regulation of cardiac muscle hypertrophy	7/988	38/18722	0.00334672729583965	0.0204342705695405	EDN1/IGF1/MEF2A/IL6ST/PPP3CA/ROCK2/ROCK1	7
GO:1903580	positive regulation of ATP metabolic process	7/988	38/18722	0.00334672729583965	0.0204342705695405	IGF1/ZBTB20/TMSB4X/APP/HIF1A/STAT3/PRKAA1	7
GO:1901215	negative regulation of neuron death	21/988	208/18722	0.00336066008987457	0.020495782316204	CD34/NDNF/F2R/MEF2C/ANGPT1/NRP1/HIPK2/MDK/CD200/FYN/PIK3CA/AP2B1/NCOA7/RHOA/HIF1A/CREB1/STAT3/TNFRSF1B/GBE1/REL/BTG2	21
GO:2000045	regulation of G1/S transition of mitotic cell cycle	16/988	142/18722	0.00339228425243857	0.0206649242533872	PLCB1/RGCC/KMT2E/RB1/PML/KLF4/PTEN/RDX/CTDSP2/PKD2/APC/CCND1/CTDSP1/WAC/ID2/PLK2	16
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	18/988	168/18722	0.00339654821179627	0.0206671982830032	FCGR2B/HLX/CEACAM1/MEF2C/IL1R1/HLA-E/HLA-A/AHR/HLA-B/B2M/CD81/PKN1/TGFB1/RC3H1/TNFRSF1B/CD46/KMT5B/RIF1	18
GO:0000302	response to reactive oxygen species	22/988	222/18722	0.00342239539544685	0.0207736774168662	EDN1/HYAL2/FOXO1/ETS1/KLF2/TXNIP/RHOB/PCGF2/PXN/DUSP1/FYN/KLF4/CAPN2/SETX/CD36/HIF1A/PKD2/PPP2CB/PRKAA1/CRK/MAPK1/JUN	22
GO:0021954	central nervous system neuron development	11/988	81/18722	0.00342969034160235	0.0207736774168662	NFIB/NDNF/NOVA2/NRP1/PTEN/GATA2/ZMIZ1/RAPGEF2/B4GALT5/BTG2/NIN	11
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	11/988	81/18722	0.00342969034160235	0.0207736774168662	CD109/SMAD6/CAV1/CAV2/FKBP1A/SKIL/LTBP1/SMURF2/SKI/HTRA1/HSPA1A	11
GO:0048144	fibroblast proliferation	11/988	81/18722	0.00342969034160235	0.0207736774168662	IGF1/DACH1/FN1/PDGFB/CDK6/PML/TP53INP1/SKI/CREB1/ZMIZ1/ZMPSTE24	11
GO:0030705	cytoskeleton-dependent intracellular transport	20/988	195/18722	0.00346787243099877	0.0209810231816235	BICD1/DST/KIF5B/ACTN4/TUBA1A/APP/ARMCX3/LAMP1/MYO10/SUN1/HIF1A/PURA/PCM1/KIF1B/MYO1C/CCDC88A/DYNC1H1/WASL/CDC42/KIFAP3	20
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	13/988	105/18722	0.00351990104065142	0.0212715748895795	FSCN1/CDC42EP5/AGRN/NRP1/NCKAP1/PIK3CA/ACTR2/ABI2/APC/CCDC88A/RALA/WASL/CDC42	13
GO:0090398	cellular senescence	12/988	93/18722	0.00352453320792065	0.0212753640914483	NUAK1/VASH1/B2M/CDK6/MAP3K3/PML/AKT3/TBX3/KAT6A/ID2/PLK2/ZMPSTE24	12
GO:0010390	histone monoubiquitination	6/988	29/18722	0.00355144986499478	0.0212798458306615	PCGF2/BCOR/RYBP/PCGF5/WAC/DTX3L	6
GO:0010592	positive regulation of lamellipodium assembly	6/988	29/18722	0.00355144986499478	0.0212798458306615	FSCN1/NCKAP1/PIK3CA/ACTR2/ABI2/CDC42	6
GO:0022011	myelination in peripheral nervous system	6/988	29/18722	0.00355144986499478	0.0212798458306615	ADGRG6/DICER1/SKI/NDRG1/PPP3R1/PLEC	6
GO:0032292	peripheral nervous system axon ensheathment	6/988	29/18722	0.00355144986499478	0.0212798458306615	ADGRG6/DICER1/SKI/NDRG1/PPP3R1/PLEC	6
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	6/988	29/18722	0.00355144986499478	0.0212798458306615	RGCC/PDGFB/CCNY/PKD2/CCND1/CCNT1	6
GO:0071222	cellular response to lipopolysaccharide	21/988	209/18722	0.00355586661151998	0.0212798458306615	VIM/PLSCR4/MEF2C/TFPI/SCARB1/PRKCE/MTDH/GIT1/SASH1/CARD16/TGFB1/CARD8/PDE4B/CAPN2/CD36/RHOA/ZFP36/ABCA1/TNFRSF1B/MAPK1/BCL10	21
GO:0035306	positive regulation of dephosphorylation	9/988	59/18722	0.00356533561545344	0.0212798458306615	CDH5/ITGA2/MEF2C/ITGA1/DLC1/PPP2R5A/CALM1/TGFB1/PPP1R12A	9
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	9/988	59/18722	0.00356533561545344	0.0212798458306615	TEK/PIK3R3/PDGFB/SOCS3/TGFB1/KLF4/SOCS4/CDC42/PTK2	9
GO:0090303	positive regulation of wound healing	9/988	59/18722	0.00356533561545344	0.0212798458306615	F2R/THBD/PRKCE/THBS1/ITGB1/PLPP3/CD36/FERMT2/PTK2	9
GO:2000351	regulation of endothelial cell apoptotic process	9/988	59/18722	0.00356533561545344	0.0212798458306615	CDH5/RAMP2/KDR/TEK/NDNF/THBS1/ANGPT1/RGCC/GATA2	9
GO:0038061	NIK/NF-kappaB signaling	16/988	143/18722	0.00363778089123933	0.021663556159488	EDN1/UACA/HDAC7/TMSB4X/ACTN4/SASH1/APP/TSPAN6/DICER1/LIMS1/NFAT5/RHOA/CYLD/EIF2AK2/RC3H1/REL	16
GO:0062013	positive regulation of small molecule metabolic process	16/988	143/18722	0.00363778089123933	0.021663556159488	IGF1/NNMT/P2RY1/ZBTB20/PRKCE/IGF2/TMSB4X/APP/CPT1A/LPGAT1/ELOVL5/HIF1A/ARPP19/STAT3/STARD4/PRKAA1	16
GO:0003015	heart process	24/988	251/18722	0.00365263479594579	0.02172765513557	EDN1/RAMP3/RPS6KA2/WWTR1/CAV1/PDE4D/CLIC2/EPAS1/THRA/SMAD5/MEF2A/GNAI2/ADRB1/CALM1/GJA1/FYN/PIK3CA/PDE4B/FLNA/ATP2B4/GJA5/GSN/CDC42/ZMPSTE24	24
GO:0050808	synapse organization	36/988	426/18722	0.0037244348825921	0.0220713159712752	SPARCL1/SPARC/FCGR2B/NFIA/ADGRL2/ARHGEF15/F2R/EFNB2/MEF2C/COL4A1/PLXND1/TANC1/AGRN/SRGN/LAMB2/NRP1/TUBA1A/PDLIM5/APP/FYN/PTEN/FLNA/ACTR2/RHOA/ABI2/NDRG1/SDCBP/ADAM10/NPTN/SEMA3F/CTTN/CTBP2/DIP2A/WASL/CDC42/NEDD4	36
GO:0001778	plasma membrane repair	4/988	13/18722	0.00375611250715979	0.0220713159712752	SYT11/MYH9/DYSF/MYOF	4
GO:0034112	positive regulation of homotypic cell-cell adhesion	4/988	13/18722	0.00375611250715979	0.0220713159712752	LGALS1/JAK1/IL6ST/F11R	4
GO:0042308	negative regulation of protein import into nucleus	4/988	13/18722	0.00375611250715979	0.0220713159712752	ANGPT1/PKIG/MDFIC/CD36	4
GO:0048711	positive regulation of astrocyte differentiation	4/988	13/18722	0.00375611250715979	0.0220713159712752	NOTCH1/IL6ST/HES1/ID2	4
GO:0071801	regulation of podosome assembly	4/988	13/18722	0.00375611250715979	0.0220713159712752	FSCN1/MSN/RHOA/GSN	4
GO:0072310	glomerular epithelial cell development	4/988	13/18722	0.00375611250715979	0.0220713159712752	PODXL/JAG1/LAMB2/IQGAP1	4
GO:0072393	microtubule anchoring at microtubule organizing center	4/988	13/18722	0.00375611250715979	0.0220713159712752	BICD1/CCDC68/PCM1/NIN	4
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	4/988	13/18722	0.00375611250715979	0.0220713159712752	THBS1/SKIL/PEA15/PTEN	4
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	4/988	13/18722	0.00375611250715979	0.0220713159712752	PLXND1/NRP1/PLXNA2/SEMA3F	4
GO:1904590	negative regulation of protein import	4/988	13/18722	0.00375611250715979	0.0220713159712752	ANGPT1/PKIG/MDFIC/CD36	4
GO:0007623	circadian rhythm	21/988	210/18722	0.00376045459828782	0.0220724141724916	ID3/AHR/ID1/ADRB1/GNAQ/PML/KMT2A/PTEN/SETX/OGT/CREB1/EGR1/CLOCK/PRKAA1/NR1D2/KLF10/ROCK2/DYRK1A/ID2/JUN/BHLHE40	21
GO:0002062	chondrocyte differentiation	13/988	106/18722	0.00382320692760508	0.0223912626234159	NFIB/ACVRL1/LOXL2/MEF2C/BMPR2/TGFBR2/SULF2/MDK/CHSY1/TGFB1/SERPINH1/EFEMP1/LTBP3	13
GO:0042116	macrophage activation	13/988	106/18722	0.00382320692760508	0.0223912626234159	CD93/FCGR2B/IL33/ADGRF5/FOXP1/SYT11/PRKCE/THBS1/CLU/APP/CD200/DYSF/PJA2	13
GO:0001913	T cell mediated cytotoxicity	8/988	49/18722	0.00383630572710736	0.0223939077169168	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/B2M/RAB27A/EMP2	8
GO:0060964	regulation of gene silencing by miRNA	8/988	49/18722	0.00383630572710736	0.0223939077169168	TGFB1/ZFP36/STAT3/TNRC6B/PPP3CA/PUM2/DDX6/ZMPSTE24	8
GO:0070849	response to epidermal growth factor	8/988	49/18722	0.00383630572710736	0.0223939077169168	ID1/ZFP36L1/CFLAR/ZFP36/IQGAP1/ZFP36L2/MAPK1/PTPN12	8
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	15/988	131/18722	0.00384387376993256	0.0224134549570601	CD109/SMAD6/CAV1/CAV2/FKBP1A/NOTCH1/SKIL/LTBP1/SMURF2/CRIM1/HIPK2/SKI/HTRA1/HSPA1A/CTDSPL2	15
GO:0007259	receptor signaling pathway via JAK-STAT	18/988	170/18722	0.00385412933997792	0.0224486129977661	IGF1/F2R/CAV1/NOTCH1/SH2B3/JAK1/SOCS3/IL6ST/FYN/PARP14/STAT3/IFNAR1/PKD2/PARP9/LEPROT/HES1/ARL2BP/PIAS1	18
GO:0071248	cellular response to metal ion	20/988	197/18722	0.00389463027498787	0.0225963291854519	EDN1/FABP4/CRHBP/MEF2C/RASA4/SYT11/B2M/MEF2A/APP/SLC12A2/CREB1/PKD2/CLIC4/ADD1/IQGAP1/PRKAA1/WNK1/MAPK1/JUN/CPNE8	20
GO:0002347	response to tumor cell	7/988	39/18722	0.00389650555984073	0.0225963291854519	CEACAM1/ADAM15/HLA-A/TXNIP/AHR/RBMS3/KLF4	7
GO:0014742	positive regulation of muscle hypertrophy	7/988	39/18722	0.00389650555984073	0.0225963291854519	EDN1/IGF1/MEF2A/IL6ST/PPP3CA/ROCK2/ROCK1	7
GO:2000249	regulation of actin cytoskeleton reorganization	7/988	39/18722	0.00389650555984073	0.0225963291854519	ESAM/TEK/TJP1/NRP1/MDK/F11R/CDC42	7
GO:0045824	negative regulation of innate immune response	10/988	71/18722	0.00395515911781806	0.022911456089258	A2M/CEACAM1/HLA-E/HLA-A/HLA-B/IFI16/PARP14/ISG15/ADAR/CRK	10
GO:0060038	cardiac muscle cell proliferation	9/988	60/18722	0.00400251186984648	0.0231605044146236	MEF2C/NOTCH1/TGFBR2/SMAD1/GJA1/PRKAR1A/PTEN/MAPK1/SAV1	9
GO:0033962	P-body assembly	5/988	21/18722	0.00406042965333766	0.0233430761023048	CNOT6L/RC3H1/DYNC1H1/DDX6/CNOT2	5
GO:0046823	negative regulation of nucleocytoplasmic transport	5/988	21/18722	0.00406042965333766	0.0233430761023048	ANGPT1/PKIG/MDFIC/CD36/SP100	5
GO:0072243	metanephric nephron epithelium development	5/988	21/18722	0.00406042965333766	0.0233430761023048	WWTR1/LAMB2/PKD2/ACAT1/HES1	5
GO:0097734	extracellular exosome biogenesis	5/988	21/18722	0.00406042965333766	0.0233430761023048	CD34/RAB27A/SDCBP/PDCD6IP/RAB11A	5
GO:2000047	regulation of cell-cell adhesion mediated by cadherin	5/988	21/18722	0.00406042965333766	0.0233430761023048	NOTCH4/TJP1/PPM1F/NOTCH1/RGCC	5
GO:2000178	negative regulation of neural precursor cell proliferation	5/988	21/18722	0.00406042965333766	0.0233430761023048	LIMS2/GATA2/CTNNA1/BTG2/SLC16A2	5
GO:0042129	regulation of T cell proliferation	18/988	171/18722	0.00410135043825405	0.0235528362464924	IGF1/LRRC32/HLA-E/HLA-A/TGFBR2/IGF2/CD81/EFNB1/IL6ST/PRKAR1A/TNFRSF14/RC3H1/TNFRSF1B/CBLB/CD46/HES1/SOS2/SOS1	18
GO:0007569	cell aging	15/988	132/18722	0.00413102826155876	0.0236976480835855	NUAK1/VASH1/B2M/CDK6/MAP3K3/PML/LIMS1/AKT3/PTEN/ZMIZ1/TBX3/KAT6A/ID2/PLK2/ZMPSTE24	15
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	13/988	107/18722	0.00414731935324981	0.0237630688577388	CAV1/CLU/RNF144B/TRIB2/PTEN/RNF19A/CSNK1A1/HECTD1/SOCS4/PTK2/HSPA1A/PIAS1/PLK2	13
GO:0050886	endocrine process	11/988	83/18722	0.00415137949924352	0.0237630688577388	EDN1/CRHBP/ECE1/FZD4/F2R/RPS6KA2/PCSK5/GJA1/RHOA/TBX3/SMAD4	11
GO:0051491	positive regulation of filopodium assembly	6/988	30/18722	0.00424442138490863	0.0241913802538998	FSCN1/AGRN/NRP1/RALA/WASL/CDC42	6
GO:0060674	placenta blood vessel development	6/988	30/18722	0.00424442138490863	0.0241913802538998	VASH1/SOCS3/NR2F2/PKD2/HES1/MAPK1	6
GO:2000637	positive regulation of gene silencing by miRNA	6/988	30/18722	0.00424442138490863	0.0241913802538998	TGFB1/ZFP36/STAT3/TNRC6B/PUM2/DDX6	6
GO:2000648	positive regulation of stem cell proliferation	6/988	30/18722	0.00424442138490863	0.0241913802538998	VEGFC/GJA1/N4BP2L2/FERMT2/TBX3/LTBP3	6
GO:0071709	membrane assembly	8/988	50/18722	0.004360294042578	0.0247789655336602	SPTBN1/CAV1/CAV2/SYT11/UGCG/PTEN/EMP2/PICALM	8
GO:0048736	appendage development	18/988	172/18722	0.00436150842883515	0.0247789655336602	MEOX2/ECE1/HOXA13/BMPR2/PCSK5/PAM/NOTCH1/MBNL1/ATRX/PLXNA2/ITGA6/SKI/FERMT2/NR2F2/TBX3/FZD6/NIPBL/SMAD4	18
GO:0060173	limb development	18/988	172/18722	0.00436150842883515	0.0247789655336602	MEOX2/ECE1/HOXA13/BMPR2/PCSK5/PAM/NOTCH1/MBNL1/ATRX/PLXNA2/ITGA6/SKI/FERMT2/NR2F2/TBX3/FZD6/NIPBL/SMAD4	18
GO:0033627	cell adhesion mediated by integrin	10/988	72/18722	0.00438113751557659	0.0248108768472738	PODXL/ITGA2/ITGA5/PIEZO1/ITGB1/JAM3/PLPP3/CRK/WNK1/PTK2	10
GO:0042246	tissue regeneration	10/988	72/18722	0.00438113751557659	0.0248108768472738	IGF1/ADAM15/NOTCH1/TGFBR2/CD81/MDK/CFLAR/CD9/PPP3CA/PTPN12	10
GO:1901880	negative regulation of protein depolymerization	10/988	72/18722	0.00438113751557659	0.0248108768472738	SPTBN1/SPTAN1/TAOK1/PIK3CA/TMOD3/RDX/ADD1/APC/GSN/CAMSAP2	10
GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	15/988	133/18722	0.00443543909371071	0.0250916426685744	CAV1/CLU/RNF144B/TRIB2/ATXN3/PTEN/RNF19A/CSNK1A1/HECTD1/SOCS4/PTK2/HSPA1A/PIAS1/PLK2/TMTC3	15
GO:0010675	regulation of cellular carbohydrate metabolic process	16/988	146/18722	0.00446329689823639	0.0251855333494699	IGFBP4/IGF1/NNMT/LEPR/P2RY1/PRKCE/IGF2/GIT1/PDK4/SCARB2/RANBP2/OGT/ARPP19/STAT3/MIDN/ZMPSTE24	16
GO:0046777	protein autophosphorylation	22/988	227/18722	0.00446972919195628	0.0251855333494699	KDR/TEK/VEGFC/ENG/CAV1/FGFR1/PEAK1/PDGFB/YES1/MAP3K3/CALM1/TAOK1/FYN/MAP3K11/EIF2AK2/IQGAP1/PIM3/PAK2/WNK1/SMG1/DYRK1A/PTK2	22
GO:0044843	cell cycle G1/S phase transition	23/988	241/18722	0.00447620754671786	0.0251855333494699	PLCB1/ITGB1/RGCC/KMT2E/RB1/CDK6/CDK17/PML/MAP3K11/KLF4/PTEN/RDX/CTDSP2/PKD2/ATP2B4/APC/PPP3CA/CCND1/CTDSP1/WAC/ID2/PIAS1/PLK2	23
GO:0030865	cortical cytoskeleton organization	9/988	61/18722	0.00448048362485864	0.0251855333494699	EHD2/RHOB/NCKAP1/AKAP11/RHOA/PLEC/PDCD6IP/ROCK2/ROCK1	9
GO:0043954	cellular component maintenance	9/988	61/18722	0.00448048362485864	0.0251855333494699	FCGR2B/F2R/TANC1/TJP1/FYN/FERMT2/CTTN/CTBP2/MTSS1	9
GO:0090342	regulation of cell aging	9/988	61/18722	0.00448048362485864	0.0251855333494699	NUAK1/VASH1/B2M/CDK6/MAP3K3/AKT3/PTEN/PLK2/ZMPSTE24	9
GO:0030866	cortical actin cytoskeleton organization	7/988	40/18722	0.00451212731019967	0.0252831437466041	EHD2/NCKAP1/AKAP11/PLEC/PDCD6IP/ROCK2/ROCK1	7
GO:0045429	positive regulation of nitric oxide biosynthetic process	7/988	40/18722	0.00451212731019967	0.0252831437466041	EDN1/KLF2/CLU/DDAH2/KLF4/CD36/PKD2	7
GO:0045777	positive regulation of blood pressure	7/988	40/18722	0.00451212731019967	0.0252831437466041	PDE4D/ADRB1/RHOA/NR2F2/F11R/WNK1/ID2	7
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	11/988	84/18722	0.00455495740631535	0.02549624208888	RB1/PML/KLF4/PTEN/CTDSP2/PKD2/APC/CCND1/CTDSP1/WAC/PLK2	11
GO:0002718	regulation of cytokine production involved in immune response	12/988	96/18722	0.00457765041723628	0.0255962937014307	BST2/IL1R1/HLA-E/HLA-A/ANGPT1/B2M/CD81/TGFB1/TNFRSF14/CD36/TNFRSF1B/BCL10	12
GO:0045931	positive regulation of mitotic cell cycle	14/988	121/18722	0.0046717059933904	0.0260897998127017	PLCB1/RGCC/KMT2E/APP/RB1/TTL/CDC25B/TMOD3/RDX/PKN2/CCND1/CDC27/HES1/RAB11A	14
GO:0000082	G1/S transition of mitotic cell cycle	21/988	214/18722	0.00467957512556182	0.0260897998127017	PLCB1/ITGB1/RGCC/KMT2E/RB1/CDK6/CDK17/PML/KLF4/PTEN/RDX/CTDSP2/PKD2/APC/PPP3CA/CCND1/CTDSP1/WAC/ID2/PIAS1/PLK2	21
GO:0034976	response to endoplasmic reticulum stress	24/988	256/18722	0.00468064367874712	0.0260897998127017	FCGR2B/CAV1/ITPR1/THBS1/CLU/SERINC3/CANX/DNAJC10/PML/ATXN3/ERO1A/SEL1L/HSP90B1/TMBIM6/EIF2AK2/EDEM3/MAN1A1/PPP2CB/CCND1/TRIM13/ATF6/HSPA1A/JUN/TMTC3	24
GO:0060402	calcium ion transport into cytosol	17/988	160/18722	0.00472489823869699	0.0263088673416755	APLNR/RAMP3/F2R/CAV1/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/PML/FYN/ERO1A/ITPR2/TMBIM6/PKD2/ATP2B4	17
GO:0048562	embryonic organ morphogenesis	26/988	285/18722	0.00478155063446255	0.0265964366180786	APLNR/EDN1/SOX18/HLX/FOXF1/MEF2C/ENG/TSHZ1/NOTCH1/TGFBR2/PCGF2/HIPK2/MIB1/HIF1A/PHACTR4/GATA2/PKD2/TBX3/FZD6/HIPK1/EFEMP1/SMAD2/NIPBL/HES1/MAPK1/ID2	26
GO:0035924	cellular response to vascular endothelial growth factor stimulus	10/988	73/18722	0.00484244063286122	0.0268788345263938	RAMP2/KDR/VEGFC/ADGRA2/TSPAN12/NOTCH1/NRP1/PIK3CA/MYO1C/ATP2B4	10
GO:0051145	smooth muscle cell differentiation	10/988	73/18722	0.00484244063286122	0.0268788345263938	APLNR/RAMP2/FOXF1/MEF2C/ENG/NOTCH1/PDGFB/TBX3/HES1/PIAS1	10
GO:0014009	glial cell proliferation	8/988	51/18722	0.00493760425942467	0.0272929800479333	LEPR/NOTCH1/CLU/DICER1/PRKCH/SKI/CREB1/HES1	8
GO:0021872	forebrain generation of neurons	8/988	51/18722	0.00493760425942467	0.0272929800479333	NDNF/B2M/NRP1/RHOA/GATA2/ZMIZ1/RAPGEF2/HES1	8
GO:0032964	collagen biosynthetic process	8/988	51/18722	0.00493760425942467	0.0272929800479333	VIM/ITGA2/F2R/ENG/RGCC/TGFB1/SERPINH1/RAP1A	8
GO:0045661	regulation of myoblast differentiation	8/988	51/18722	0.00493760425942467	0.0272929800479333	MEF2C/ID3/PLCB1/NOTCH1/ZFP36L1/TGFB1/IGFBP3/TBX3	8
GO:0035335	peptidyl-tyrosine dephosphorylation	12/988	97/18722	0.00497980975418371	0.0273248077421507	PTPRB/DUSP1/DUSP6/CDC25B/PTEN/MTMR6/PTPRM/PTPRG/PTP4A2/PTPN14/PTPRA/PTPN12	12
GO:0001656	metanephros development	11/988	85/18722	0.00498905855320997	0.0273248077421507	CD34/WWTR1/ID3/LAMB2/PDGFB/PKD2/ACAT1/EGR1/NIPBL/HES1/SMAD4	11
GO:0060021	roof of mouth development	11/988	85/18722	0.00498905855320997	0.0273248077421507	CLDN5/MEOX2/LRRC32/TSHZ1/TGFBR2/BCOR/SKI/TBX3/SMAD2/SOS1/SMAD4	11
GO:0048002	antigen processing and presentation of peptide antigen	9/988	62/18722	0.00500174155143907	0.0273248077421507	FCGR2B/HLA-E/HLA-A/HLA-B/HLA-C/B2M/ERAP1/LNPEP/TAPBP	9
GO:0035024	negative regulation of Rho protein signal transduction	5/988	22/18722	0.00502968931962975	0.0273248077421507	HEG1/RASIP1/DLC1/ITGB1/TNFAIP1	5
GO:0035561	regulation of chromatin binding	5/988	22/18722	0.00502968931962975	0.0273248077421507	HMBOX1/PARP9/PPP3CA/CTBP2/DTX3L	5
GO:0071404	cellular response to low-density lipoprotein particle stimulus	5/988	22/18722	0.00502968931962975	0.0273248077421507	ITGB1/CD81/CD36/ABCA1/CD9	5
GO:0072574	hepatocyte proliferation	5/988	22/18722	0.00502968931962975	0.0273248077421507	LIMS2/CEACAM1/SULF2/MDK/CFLAR	5
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	5/988	22/18722	0.00502968931962975	0.0273248077421507	LIMS2/CEACAM1/SULF2/MDK/CFLAR	5
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	5/988	22/18722	0.00502968931962975	0.0273248077421507	NOTCH1/SMAD5/SMAD1/HIF1A/SMAD4	5
GO:2000114	regulation of establishment of cell polarity	5/988	22/18722	0.00502968931962975	0.0273248077421507	CDH5/RUFY3/GSN/ROCK2/ROCK1	5
GO:0032509	endosome transport via multivesicular body sorting pathway	6/988	31/18722	0.00503230019622947	0.0273248077421507	LEPROTL1/LYST/TMEM50B/LEPROT/TMEM50A/VPS36	6
GO:0060148	positive regulation of posttranscriptional gene silencing	6/988	31/18722	0.00503230019622947	0.0273248077421507	TGFB1/ZFP36/STAT3/TNRC6B/PUM2/DDX6	6
GO:0003188	heart valve formation	4/988	14/18722	0.0050410978138757	0.0273248077421507	DCHS1/NOTCH1/GJA5/SMAD4	4
GO:0034111	negative regulation of homotypic cell-cell adhesion	4/988	14/18722	0.0050410978138757	0.0273248077421507	CEACAM1/SH2B3/RDX/CD9	4
GO:0035563	positive regulation of chromatin binding	4/988	14/18722	0.0050410978138757	0.0273248077421507	HMBOX1/PARP9/CTBP2/DTX3L	4
GO:0035810	positive regulation of urine volume	4/988	14/18722	0.0050410978138757	0.0273248077421507	EDN1/NPR1/HYAL2/GNAI2	4
GO:0042921	glucocorticoid receptor signaling pathway	4/988	14/18722	0.0050410978138757	0.0273248077421507	CLOCK/NR3C1/NEDD4/ARID1A	4
GO:0070278	extracellular matrix constituent secretion	4/988	14/18722	0.0050410978138757	0.0273248077421507	ENG/NOTCH1/RGCC/TNFRSF1B	4
GO:0001101	response to acid chemical	15/988	135/18722	0.00509903943557014	0.0276107007968895	EDN1/COL18A1/COL4A1/KLF2/FYN/PIK3CA/CAPN2/RHOA/TMBIM6/CREB1/PKD2/ATP2B4/CD9/PLEC/ATF2	15
GO:1904407	positive regulation of nitric oxide metabolic process	7/988	41/18722	0.00519835693689938	0.0281198289702744	EDN1/KLF2/CLU/DDAH2/KLF4/CD36/PKD2	7
GO:0051656	establishment of organelle localization	33/988	390/18722	0.0052303420361252	0.0282640660182066	BICD1/FOXF1/EXOC6/SYT11/MAP4K2/ITGB1/KIF5B/ACTN4/TTL/GJA1/ARMCX3/MYH9/LAMP1/ACTR2/RAB27A/SUN1/HIF1A/GATA2/PCM1/SNAP23/MYO1C/S100A13/PICALM/WDR11/MAP4/RAB11A/FAM91A1/DYNC1H1/WASL/CDC42/XPO1/KIFAP3/STARD3NL	33
GO:0007088	regulation of mitotic nuclear division	13/988	110/18722	0.0052547455647563	0.0283382826801883	EDN1/IGF1/HOXA13/CAV2/IGF2/RGCC/PDGFB/RB1/DUSP1/APC/CDC27/PHIP/CDC42	13
GO:0061387	regulation of extent of cell growth	13/988	110/18722	0.0052547455647563	0.0283382826801883	FN1/BMPR2/MACF1/NRP1/TTL/DPYSL2/GDI1/SEMA3F/RTN4/CTTN/RUFY3/RAB11A/EIF4G2	13
GO:0034249	negative regulation of cellular amide metabolic process	25/988	273/18722	0.00532972684122515	0.0287134979519148	IGF1/CLU/ZFP36L1/PABPC1/ZFP36/PURA/STAT3/EIF2AK2/TNRC6B/CELF1/CNOT6L/RTN4/RC3H1/ENC1/ZFP36L2/PRKAA1/CNOT8/ROCK2/DDX6/TNRC6A/ROCK1/CNOT2/XRN1/BTG2/TIA1	25
GO:0048332	mesoderm morphogenesis	10/988	74/18722	0.00534102063308256	0.028745189060724	FOXF1/ITGA2/BMPR2/ITGB1/SMAD1/GJA1/PRKAR1A/KLF4/TBX3/SMAD2	10
GO:0002367	cytokine production involved in immune response	12/988	98/18722	0.00540963830630807	0.0290850189100288	BST2/IL1R1/HLA-E/HLA-A/ANGPT1/B2M/CD81/TGFB1/TNFRSF14/CD36/TNFRSF1B/BCL10	12
GO:0060541	respiratory system development	20/988	203/18722	0.00544429213979915	0.0292417389753418	SPARC/NFIB/HEG1/FOXF1/BMPR2/EPAS1/THRA/KLF2/NOTCH1/TGFBR2/SKI/CREB1/PPP3R1/LIPA/LTBP3/SMAD2/HES1/CDC42/MAPK1/SAV1	20
GO:0014031	mesenchymal cell development	11/988	86/18722	0.00545524891403591	0.0292657061057091	EDN1/FN1/JAG1/NOTCH1/NRP1/EFNB1/HIF1A/PHACTR4/SEMA3F/HES1/MAPK1	11
GO:0098876	vesicle-mediated transport to the plasma membrane	15/988	136/18722	0.00545977310819988	0.0292657061057091	SPTBN1/STXBP6/EHD2/EXOC6/ANKRD50/MACF1/VAMP5/EXOC5/STX3/ACSL3/ACAP2/KIAA1109/EHD4/RAB11A/GOLGA7	15
GO:0050854	regulation of antigen receptor-mediated signaling pathway	9/988	63/18722	0.00556882345250675	0.0298201513908426	FCGR2B/CEACAM1/FOXP1/CD81/PRKCH/CMTM3/RC3H1/CBLB/BCL10	9
GO:0010977	negative regulation of neuron projection development	15/988	137/18722	0.00584085048176493	0.0311825103106887	VIM/EFNB2/B2M/NRP1/LGALS1/PTEN/GDI1/FLNA/RHOA/MAP4K4/PTPRG/SEMA3F/RTN4/RUFY3/THOC2	15
GO:0055123	digestive system development	15/988	137/18722	0.00584085048176493	0.0311825103106887	HLX/FOXF1/DCHS1/PCSK5/NOTCH1/TGFBR2/IGF2/RB1/IL6ST/HIF1A/SMAD2/NIPBL/HES1/ID2/SAV1	15
GO:0090090	negative regulation of canonical Wnt signaling pathway	15/988	137/18722	0.00584085048176493	0.0311825103106887	IGFBP4/TMEM88/FZD4/WWTR1/CAV1/NOTCH1/RBMS3/MDK/CTNND1/CYLD/EGR1/FZD6/CSNK1A1/APC/G3BP1	15
GO:0051302	regulation of cell division	18/988	177/18722	0.00587422961397068	0.0313292246078436	VEGFC/PKP4/PRKCE/TXNIP/IGF2/PDGFB/GIT1/MDK/CALM1/TGFB1/CDC25B/RHOA/PKN2/KLHL9/SH3GLB1/RAB11A/CDC42/PLK2	18
GO:0035767	endothelial cell chemotaxis	6/988	32/18722	0.00592233966804459	0.0314707600119127	KDR/FGFR1/THBS1/NOTCH1/TMSB4X/NRP1	6
GO:0071875	adrenergic receptor signaling pathway	6/988	32/18722	0.00592233966804459	0.0314707600119127	PDE4D/GNAI2/ADRB1/PDE4B/RAPGEF2/ATP2B4	6
GO:0001776	leukocyte homeostasis	11/988	87/18722	0.0059551240708045	0.0314707600119127	MEF2C/SH2B3/SKIL/PKN1/JAM3/PDE4B/HIF1A/RC3H1/SOS2/SOS1/BCL10	11
GO:1901879	regulation of protein depolymerization	11/988	87/18722	0.0059551240708045	0.0314707600119127	SPTBN1/SPTAN1/TAOK1/PIK3CA/TMOD3/RDX/ADD1/APC/GSN/DSTN/CAMSAP2	11
GO:1903578	regulation of ATP metabolic process	11/988	87/18722	0.0059551240708045	0.0314707600119127	IGF1/ZBTB20/COX7A1/TMSB4X/GIT1/APP/RHOA/HIF1A/OGT/STAT3/PRKAA1	11
GO:0016601	Rac protein signal transduction	7/988	42/18722	0.00596001215587051	0.0314707600119127	ELMO1/HACE1/NCKAP1/ABI2/OGT/CRK/ARHGAP17	7
GO:0021879	forebrain neuron differentiation	7/988	42/18722	0.00596001215587051	0.0314707600119127	NDNF/B2M/NRP1/GATA2/ZMIZ1/RAPGEF2/HES1	7
GO:0032965	regulation of collagen biosynthetic process	7/988	42/18722	0.00596001215587051	0.0314707600119127	VIM/ITGA2/F2R/ENG/RGCC/TGFB1/RAP1A	7
GO:0033574	response to testosterone	7/988	42/18722	0.00596001215587051	0.0314707600119127	EDN1/MSN/THBS1/DUSP1/CFLAR/ROCK2/XRN1	7
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	7/988	42/18722	0.00596001215587051	0.0314707600119127	MMRN2/MEOX2/THBS1/NOTCH1/KLF4/RHOA/STARD13	7
GO:0062012	regulation of small molecule metabolic process	29/988	334/18722	0.00600147552392682	0.0316582303705057	IGFBP4/IGF1/NNMT/LEPR/P2RY1/ZBTB20/CEACAM1/CAV1/PRKCE/FABP5/IGF2/TMSB4X/GIT1/PDK4/APP/CPT1A/LPGAT1/ELOVL5/RANBP2/HIF1A/OGT/ARPP19/STAT3/EGR1/ATP2B4/STARD4/PRKAA1/MIDN/ZMPSTE24	29
GO:0044772	mitotic cell cycle phase transition	35/988	424/18722	0.00603070992951656	0.0317808840730079	PLCB1/ITGB1/RGCC/ZFP36L1/KMT2E/APP/RB1/CDK6/CCNY/CALM1/DUSP1/CDK17/PML/TAOK1/CDC25B/TMOD3/KLF4/PTEN/RDX/ARPP19/CTDSP2/PKD2/APC/PPP3CA/CCND1/ZFP36L2/CDC27/CCNI/CTDSP1/WAC/RAB11A/FOXN3/ID2/PIAS1/PLK2	35
GO:0002700	regulation of production of molecular mediator of immune response	17/988	164/18722	0.00604670672967463	0.0318336037146002	FCGR2B/BST2/IL1R1/HLA-E/HLA-A/ANGPT1/B2M/CD81/PKN1/TGFB1/TNFRSF14/CD36/TMBIM6/TNFRSF1B/KMT5B/RIF1/BCL10	17
GO:0050765	negative regulation of phagocytosis	5/988	23/18722	0.00615206667307397	0.0322603930576199	FCGR2B/SYT11/PTEN/DYSF/PLSCR1	5
GO:0060396	growth hormone receptor signaling pathway	5/988	23/18722	0.00615206667307397	0.0322603930576199	PXN/LEPROTL1/STAT3/LEPROT/PTK2	5
GO:0072576	liver morphogenesis	5/988	23/18722	0.00615206667307397	0.0322603930576199	LIMS2/CEACAM1/SULF2/MDK/CFLAR	5
GO:0140112	extracellular vesicle biogenesis	5/988	23/18722	0.00615206667307397	0.0322603930576199	CD34/RAB27A/SDCBP/PDCD6IP/RAB11A	5
GO:0030837	negative regulation of actin filament polymerization	9/988	64/18722	0.00618430855078762	0.0323974822700038	SPTBN1/KANK3/SPTAN1/TMSB4X/TMSB10/TMOD3/RDX/ADD1/GSN	9
GO:0002707	negative regulation of lymphocyte mediated immunity	8/988	53/18722	0.00626583884749004	0.0327277639703708	FCGR2B/CEACAM1/HLA-E/HLA-A/AHR/HLA-B/CRK/CD46	8
GO:0071320	cellular response to cAMP	8/988	53/18722	0.00626583884749004	0.0327277639703708	CRHBP/AHR/ZFP36L1/APP/ITPR2/PKD2/RAPGEF2/RAP1A	8
GO:2000772	regulation of cellular senescence	8/988	53/18722	0.00626583884749004	0.0327277639703708	NUAK1/VASH1/B2M/CDK6/MAP3K3/AKT3/PLK2/ZMPSTE24	8
GO:0006650	glycerophospholipid metabolic process	27/988	306/18722	0.00636330305486289	0.0332041904002276	PLA1A/ENPP2/SCARB1/PLCB1/FABP5/DGKH/SERINC3/PIK3R3/PDGFB/SERINC1/OSBPL10/SOCS3/LPGAT1/PIK3CA/PIK3C2B/ACSL3/PTEN/CAPN2/SLC44A2/MTMR6/SLC44A1/PIK3C2A/PLSCR1/SOCS4/SMG1/FAR1/ETNK1	27
GO:0010232	vascular transport	11/988	88/18722	0.00649030693093372	0.0338336706743081	LEPR/FABP5/SLC38A2/SLC12A2/GJA1/CD36/SLC44A1/SLC2A1/ATP2B4/SLC2A3/SLC16A2	11
GO:0031056	regulation of histone modification	16/988	152/18722	0.00657376862387757	0.0338904227007016	APLNR/NNMT/IGF2/BCOR/KMT2E/ATRX/KMT2A/SKI/OGT/GATA2/EID1/NIPBL/TRIP12/RIF1/SMAD4/ZMPSTE24	16
GO:0044344	cellular response to fibroblast growth factor stimulus	13/988	113/18722	0.00658724946949175	0.0338904227007016	KL/NDNF/HYAL2/FGFR1/THBS1/ZFP36L1/SULF2/SETX/ZFP36/NPTN/CD44/ZFP36L2/SHOC2	13
GO:0010950	positive regulation of endopeptidase activity	18/988	179/18722	0.00658817332950632	0.0338904227007016	SOX7/F2R/UACA/TNFSF10/HIP1/DLC1/PPM1F/IFI16/PML/CFLAR/FYN/CARD8/RHOA/STAT3/PICALM/GSN/ROCK2/BCL10	18
GO:0021542	dentate gyrus development	4/988	15/18722	0.00659051330004232	0.0338904227007016	CDK6/MDK/PTEN/BTG2	4
GO:0031958	corticosteroid receptor signaling pathway	4/988	15/18722	0.00659051330004232	0.0338904227007016	CLOCK/NR3C1/NEDD4/ARID1A	4
GO:0032486	Rap protein signal transduction	4/988	15/18722	0.00659051330004232	0.0338904227007016	RDX/RAPGEF2/PLK2/RAP1A	4
GO:0032488	Cdc42 protein signal transduction	4/988	15/18722	0.00659051330004232	0.0338904227007016	RHOJ/NRP1/ABCA1/CDC42	4
GO:0045217	cell-cell junction maintenance	4/988	15/18722	0.00659051330004232	0.0338904227007016	F2R/TJP1/FERMT2/MTSS1	4
GO:0051127	positive regulation of actin nucleation	4/988	15/18722	0.00659051330004232	0.0338904227007016	NCKAP1/ABI2/GSN/WASL	4
GO:0060253	negative regulation of glial cell proliferation	4/988	15/18722	0.00659051330004232	0.0338904227007016	NOTCH1/DICER1/SKI/HES1	4
GO:0072224	metanephric glomerulus development	4/988	15/18722	0.00659051330004232	0.0338904227007016	CD34/LAMB2/PDGFB/EGR1	4
GO:0099170	postsynaptic modulation of chemical synaptic transmission	4/988	15/18722	0.00659051330004232	0.0338904227007016	PLCB1/RNF19A/PPP3R1/PPP3CA	4
GO:1903729	regulation of plasma membrane organization	4/988	15/18722	0.00659051330004232	0.0338904227007016	MYH9/GSN/SH3GLB1/WASL	4
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	4/988	15/18722	0.00659051330004232	0.0338904227007016	TGFB1/STAT3/PPP3CA/ZMPSTE24	4
GO:0030216	keratinocyte differentiation	15/988	139/18722	0.00666728687482006	0.0342520579101007	CD109/JAG1/TXNIP/NOTCH1/UGCG/ZFP36L1/FLNB/PRKCH/PALLD/ZFP36/CLIC4/PLEC/ROCK2/ROCK1/SAV1	15
GO:0032874	positive regulation of stress-activated MAPK cascade	14/988	126/18722	0.00668023788361066	0.0342723704094486	FCGR2B/PLCB1/MAP4K2/SASH1/HIPK2/APP/MAP3K3/TAOK1/MAP3K11/SDCBP/EIF2AK2/RB1CC1/PJA2/CDC42	14
GO:0022898	regulation of transmembrane transporter activity	25/988	278/18722	0.00668414453015602	0.0342723704094486	CRHBP/MEF2C/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/ITGB1/TMSB4X/UTRN/KIF5B/STOM/ACTN4/APP/CALM1/GJA1/STIM2/PTEN/PDE4B/AHNAK/PKD2/FXYD5/CRBN/WNK1/NEDD4	25
GO:2000116	regulation of cysteine-type endopeptidase activity	22/988	235/18722	0.00669144002381113	0.034276691809532	SOX7/F2R/UACA/TNFSF10/HIP1/DLC1/THBS1/PPM1F/IFI16/RPS6KA3/CARD16/XIAP/PML/CFLAR/FYN/CARD8/KLF4/RHOA/CD44/PAK2/GSN/BCL10	22
GO:0001709	cell fate determination	7/988	43/18722	0.00680194425833293	0.0346941099448031	NOTCH4/MEF2C/JAG1/KLF4/GATA2/HES1/CDC42	7
GO:0033173	calcineurin-NFAT signaling cascade	7/988	43/18722	0.00680194425833293	0.0346941099448031	IGF1/LMCD1/RCAN1/NFAT5/PPP3R1/ATP2B4/PPP3CA	7
GO:0045981	positive regulation of nucleotide metabolic process	7/988	43/18722	0.00680194425833293	0.0346941099448031	IGF1/ZBTB20/TMSB4X/APP/HIF1A/STAT3/PRKAA1	7
GO:1900544	positive regulation of purine nucleotide metabolic process	7/988	43/18722	0.00680194425833293	0.0346941099448031	IGF1/ZBTB20/TMSB4X/APP/HIF1A/STAT3/PRKAA1	7
GO:0006887	exocytosis	30/988	352/18722	0.00680686116293715	0.0346941099448031	FCGR2B/CRHBP/STXBP6/P2RY1/CEACAM1/FOXF1/EXOC6/SYT11/NOTCH1/GIT1/GNAI2/CALM1/EXOC5/STX3/MYH9/LAMP1/RAB27A/PIK3C2A/SCAMP1/SDCBP/RALB/GATA2/SNAP23/S100A13/CTBP2/PDCD6IP/RALA/RAB11A/RAB5A/RAP1A	30
GO:0061013	regulation of mRNA catabolic process	17/988	166/18722	0.00681211533743027	0.0346941099448031	VIM/ZFP36L1/PABPC1/ZFP36/TNRC6B/CELF1/CNOT6L/ZC3HAV1/RC3H1/ZFP36L2/CNOT8/PUM2/ROCK2/TNRC6A/ROCK1/CNOT2/BTG2	17
GO:0140694	non-membrane-bounded organelle assembly	31/988	367/18722	0.00681975919803257	0.0346997709386485	EDN1/FSCN1/BICD1/MSN/ITGB1/MEF2A/CFLAR/PRKAR1A/TMOD3/CCDC69/POGZ/FLNA/RHOA/CSDE1/CNOT6L/RC3H1/STAG2/G3BP1/PRKAA1/PLEC/GSN/NEK7/RAB11A/PUM2/DYNC1H1/DDX6/CNOT2/HSPA1A/PLK2/SMAD4/SENP6	31
GO:0048524	positive regulation of viral process	9/988	65/18722	0.0068508115324275	0.034824412306464	CAV2/NOTCH1/STOM/MDFIC/LGALS1/PABPC1/ADAR/PKN2/RSF1	9
GO:0006476	protein deacetylation	12/988	101/18722	0.0068782892488678	0.0349306620363153	APLNR/NNMT/FRY/HDAC7/ELK4/FLNA/SKI/TBL1XR1/PRKAA1/NIPBL/DYRK1A/BAZ2A	12
GO:0045648	positive regulation of erythrocyte differentiation	6/988	33/18722	0.00692177728955117	0.0350509828046671	ETS1/ISG15/HIF1A/STAT3/GATA2/HSPA1A	6
GO:0048333	mesodermal cell differentiation	6/988	33/18722	0.00692177728955117	0.0350509828046671	FOXF1/ITGA2/ITGB1/SMAD1/GJA1/KLF4	6
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	6/988	33/18722	0.00692177728955117	0.0350509828046671	RGCC/PDGFB/CCNY/PKD2/CCND1/CCNT1	6
GO:0030834	regulation of actin filament depolymerization	8/988	54/18722	0.00702369390909523	0.0355332019477275	SPTBN1/SPTAN1/PIK3CA/TMOD3/RDX/ADD1/GSN/DSTN	8
GO:0014910	regulation of smooth muscle cell migration	11/988	89/18722	0.00706244532352912	0.0356274544715923	IGF1/ITGA2/MEF2C/DOCK4/NRP1/PDGFB/MDK/IGFBP3/RHOA/IQGAP1/CRK	11
GO:0046330	positive regulation of JNK cascade	11/988	89/18722	0.00706244532352912	0.0356274544715923	FCGR2B/PLCB1/MAP4K2/HIPK2/APP/TAOK1/MAP3K11/SDCBP/RB1CC1/PJA2/CDC42	11
GO:0051781	positive regulation of cell division	11/988	89/18722	0.00706244532352912	0.0356274544715923	VEGFC/PKP4/PRKCE/IGF2/PDGFB/MDK/TGFB1/CDC25B/RHOA/PKN2/CDC42	11
GO:0002244	hematopoietic progenitor cell differentiation	13/988	114/18722	0.00708661012449395	0.0356815857642766	KDR/TCF15/HYAL2/NOTCH1/JAM3/TGFB1/N4BP2L2/EIF2AK2/ADAR/ATF2/HES1/SOS2/SOS1	13
GO:1901800	positive regulation of proteasomal protein catabolic process	13/988	114/18722	0.00708661012449395	0.0356815857642766	CAV1/CLU/RNF144B/TRIB2/ATXN3/RNF19A/CSNK1A1/HECTD1/SOCS4/HSPA1A/PIAS1/PLK2/TMTC3	13
GO:0002573	myeloid leukocyte differentiation	20/988	208/18722	0.00709418647597279	0.0356859077276207	CD109/CEACAM1/FOXP1/IFI16/TGFBR2/CD81/ZFP36L1/APP/RB1/CDK6/TGFB1/MYH9/GLO1/CREB1/GATA2/LBR/KLF10/CDC42/ID2/JUN	20
GO:0048565	digestive tract development	14/988	127/18722	0.00715435562861712	0.0359545289491146	HLX/FOXF1/DCHS1/PCSK5/NOTCH1/TGFBR2/RB1/IL6ST/HIF1A/SMAD2/NIPBL/HES1/ID2/SAV1	14
GO:0031960	response to corticosteroid	17/988	167/18722	0.00722316119359573	0.0362660040268247	SPARC/EDN1/ENG/FOXO1/PAM/NOTCH1/IGFBP7/ZFP36L1/MDK/CALM1/DUSP1/CFLAR/RHOA/ZFP36/CCND1/ZFP36L2/NR3C1	17
GO:0050770	regulation of axonogenesis	16/988	154/18722	0.00743371249960029	0.0371057381380008	PLXND1/FN1/BMPR2/MACF1/SKIL/NRP1/PLXNA2/PTEN/GDI1/SEMA3F/RTN4/RUFY3/PAK2/RAB11A/EIF4G2/NIN	16
GO:0050855	regulation of B cell receptor signaling pathway	5/988	24/18722	0.00743930932171892	0.0371057381380008	FCGR2B/FOXP1/CD81/PRKCH/CMTM3	5
GO:0060149	negative regulation of posttranscriptional gene silencing	5/988	24/18722	0.00743930932171892	0.0371057381380008	TGFB1/STAT3/ADAR/PPP3CA/ZMPSTE24	5
GO:0060967	negative regulation of gene silencing by RNA	5/988	24/18722	0.00743930932171892	0.0371057381380008	TGFB1/STAT3/ADAR/PPP3CA/ZMPSTE24	5
GO:0071378	cellular response to growth hormone stimulus	5/988	24/18722	0.00743930932171892	0.0371057381380008	PXN/LEPROTL1/STAT3/LEPROT/PTK2	5
GO:0071676	negative regulation of mononuclear cell migration	5/988	24/18722	0.00743930932171892	0.0371057381380008	PLCB1/DUSP1/CD200/LRCH1/WASL	5
GO:2001026	regulation of endothelial cell chemotaxis	5/988	24/18722	0.00743930932171892	0.0371057381380008	KDR/FGFR1/THBS1/NOTCH1/TMSB4X	5
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	20/988	209/18722	0.00746861185845458	0.0372169476473834	SOX7/F2R/UACA/TNFSF10/HIP1/DLC1/THBS1/PPM1F/RPS6KA3/CARD16/XIAP/PML/CFLAR/CARD8/KLF4/RHOA/CD44/PAK2/GSN/BCL10	20
GO:0032409	regulation of transporter activity	27/988	310/18722	0.00752192190317573	0.0374474687438327	CRHBP/MEF2C/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/ITGB1/TMSB4X/UTRN/KIF5B/STOM/ACTN4/APP/CTTNBP2NL/CALM1/GJA1/STIM2/KMT2A/PTEN/PDE4B/AHNAK/PKD2/FXYD5/CRBN/WNK1/NEDD4	27
GO:0014015	positive regulation of gliogenesis	9/988	66/18722	0.00757097637447724	0.037621166044175	NOTCH1/MDK/DICER1/PRKCH/IL6ST/TGFB1/TNFRSF1B/HES1/ID2	9
GO:0019229	regulation of vasoconstriction	9/988	66/18722	0.00757097637447724	0.037621166044175	EDN1/ECE1/F2R/CAV1/BMPR2/DOCK4/GJA1/RHOA/GJA5	9
GO:1902806	regulation of cell cycle G1/S phase transition	17/988	168/18722	0.00765397192664602	0.0378962601779242	PLCB1/RGCC/KMT2E/RB1/PML/KLF4/PTEN/RDX/CTDSP2/PKD2/ATP2B4/APC/CCND1/CTDSP1/WAC/ID2/PLK2	17
GO:0032612	interleukin-1 production	14/988	128/18722	0.00765487333789772	0.0378962601779242	IGF1/CEACAM1/F2R/FOXP1/IFI16/GIT1/CARD16/APP/PML/CARD8/CD36/STAT3/EGR1/S100A13	14
GO:0032652	regulation of interleukin-1 production	14/988	128/18722	0.00765487333789772	0.0378962601779242	IGF1/CEACAM1/F2R/FOXP1/IFI16/GIT1/CARD16/APP/PML/CARD8/CD36/STAT3/EGR1/S100A13	14
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	14/988	128/18722	0.00765487333789772	0.0378962601779242	FCGR2B/PLCB1/MAP4K2/SASH1/HIPK2/APP/MAP3K3/TAOK1/MAP3K11/SDCBP/EIF2AK2/RB1CC1/PJA2/CDC42	14
GO:0030901	midbrain development	11/988	90/18722	0.00767320948151892	0.0379163616426312	LRP6/SMAD1/CALM1/GNB4/KDM7A/RHOA/FZD6/ZNF148/HES1/CDC42/SOS1	11
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	11/988	90/18722	0.00767320948151892	0.0379163616426312	CAV1/CLU/RNF144B/TRIB2/RNF19A/CSNK1A1/HECTD1/SOCS4/HSPA1A/PIAS1/PLK2	11
GO:0008542	visual learning	7/988	44/18722	0.00772901819021385	0.0380505510902836	TANC1/ITGB1/APP/HIF1A/CREB1/NPTN/PIAS1	7
GO:0030521	androgen receptor signaling pathway	7/988	44/18722	0.00772901819021385	0.0380505510902836	PLPP1/FOXP1/DDX17/PKN1/RHOA/ZMIZ1/ARID1A	7
GO:0060711	labyrinthine layer development	7/988	44/18722	0.00772901819021385	0.0380505510902836	RSPO3/PCDH12/VASH1/ZFP36L1/SOCS3/HES1/MAPK1	7
GO:0062208	positive regulation of pattern recognition receptor signaling pathway	7/988	44/18722	0.00772901819021385	0.0380505510902836	CAV1/DDX60/RTN4/WDFY1/PJA2/PUM2/HSPA1A	7
GO:0032412	regulation of ion transmembrane transporter activity	24/988	267/18722	0.00780703477829041	0.0383990451317395	CRHBP/MEF2C/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/ITGB1/TMSB4X/UTRN/KIF5B/STOM/ACTN4/APP/CALM1/STIM2/PTEN/PDE4B/AHNAK/PKD2/FXYD5/CRBN/WNK1/NEDD4	24
GO:0038066	p38MAPK cascade	8/988	55/18722	0.00784871109381264	0.0385326740576088	ZFP36L1/SASH1/MAP3K3/DUSP1/ZFP36/CYLD/PJA2/ATF2	8
GO:1905517	macrophage migration	8/988	55/18722	0.00784871109381264	0.0385326740576088	MTUS1/THBS1/CD81/MDK/CD200/CD9/PTK2/MAPK1	8
GO:0051147	regulation of muscle cell differentiation	16/988	155/18722	0.00789629960347755	0.0387305110744901	EDN1/IGF1/EFNB2/MEF2C/ENG/BMPR2/PIEZO1/NOTCH1/IGF2/ATP11A/SMAD1/PDGFB/TGFB1/ID2/PIAS1/SMAD4	16
GO:0001654	eye development	31/988	371/18722	0.00792774539406447	0.03884887779822	VIM/ACVRL1/RHOJ/FZD4/ARHGEF15/COL4A1/BMPR2/JAG1/TSPAN12/LAMB2/TGFBR2/SKIL/CRYBG3/NRP1/HIPK2/GNB1/KLF4/TUG1/ABI2/HIF1A/SKI/PTPRM/PHACTR4/STAT3/CLIC4/ATP2B4/HIPK1/EFEMP1/ATF6/NIPBL/SOS1	31
GO:0008654	phospholipid biosynthetic process	23/988	253/18722	0.00796817346684483	0.0390110022634836	ADGRF5/FABP5/SPTLC2/DGKH/PIK3R3/PDGFB/SERINC1/SOCS3/LPGAT1/PIK3CA/PIK3C2B/ACSL3/PTEN/CAPN2/SLC44A2/MTMR6/SLC44A1/PIK3C2A/PLSCR1/SOCS4/SMG1/FAR1/ETNK1	23
GO:0035308	negative regulation of protein dephosphorylation	6/988	34/18722	0.00803779355735685	0.0392794474486473	FKBP1A/GNAI2/ARPP19/ROCK2/ROCK1/YWHAB	6
GO:1990000	amyloid fibril formation	6/988	34/18722	0.00803779355735685	0.0392794474486473	FKBP1A/CLU/B2M/APP/CD36/GSN	6
GO:0034284	response to monosaccharide	21/988	225/18722	0.00820468115211875	0.0400581491544621	SPARC/ZBTB20/ITGA2/ANGPT2/PRKCE/TXNIP/THBS1/TGFBR2/KIF5B/LGALS1/GJA1/PIK3CA/PTEN/RHOA/HIF1A/MAP4K4/EGR1/PPP3CA/PIM3/PRKAA1/SMAD2	21
GO:0055006	cardiac cell development	11/988	91/18722	0.00832428941713904	0.0405763952294396	EDN1/IGF1/SORBS2/JAG1/NOTCH1/MEF2A/PDLIM5/TBX3/PLEC/SMAD4/ZMPSTE24	11
GO:0072665	protein localization to vacuole	9/988	67/18722	0.00834746998497535	0.0405763952294396	CLU/CD81/SCARB2/RTN4/VPS13C/SH3GLB1/ROCK2/NEDD4/VPS36	9
GO:0001764	neuron migration	16/988	156/18722	0.00838163807433277	0.0405763952294396	COL3A1/NDNF/MEF2C/FGFR1/NRP1/MDK/FYN/FLNA/STAT3/GATA2/PCM1/NR2F2/ZMIZ1/RAPGEF2/CRK/NIPBL	16
GO:0009267	cellular response to starvation	16/988	156/18722	0.00838163807433277	0.0405763952294396	NUAK1/BMPR2/FOXO1/SLC38A2/IFI16/PDK4/RALB/EIF2AK2/SLC2A1/PRKAA1/XPR1/KLF10/SH3GLB1/TNRC6A/MAPK1/JUN	16
GO:0048511	rhythmic process	26/988	298/18722	0.00842294642681739	0.0405763952294396	FZD4/ETS1/ID3/PAM/AHR/ID1/MDK/ADRB1/GNAQ/PML/KMT2A/PTEN/SETX/OGT/CREB1/EGR1/CLOCK/CREM/PRKAA1/NR1D2/KLF10/ROCK2/DYRK1A/ID2/JUN/BHLHE40	26
GO:0002693	positive regulation of cellular extravasation	4/988	16/18722	0.00842540736785991	0.0405763952294396	PLVAP/IL1R1/MDK/JAM3	4
GO:0002921	negative regulation of humoral immune response	4/988	16/18722	0.00842540736785991	0.0405763952294396	A2M/FCGR2B/CD59/CD46	4
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	4/988	16/18722	0.00842540736785991	0.0405763952294396	ENG/NOTCH1/TGFBR2/SMAD4	4
GO:0030033	microvillus assembly	4/988	16/18722	0.00842540736785991	0.0405763952294396	PODXL/FSCN1/FXYD5/RAPGEF2	4
GO:0048557	embryonic digestive tract morphogenesis	4/988	16/18722	0.00842540736785991	0.0405763952294396	HLX/FOXF1/NIPBL/ID2	4
GO:0072148	epithelial cell fate commitment	4/988	16/18722	0.00842540736785991	0.0405763952294396	HOXA13/NOTCH1/NRP1/NR2F2	4
GO:0097284	hepatocyte apoptotic process	4/988	16/18722	0.00842540736785991	0.0405763952294396	RB1/CFLAR/GSN/ATF2	4
GO:1905153	regulation of membrane invagination	4/988	16/18722	0.00842540736785991	0.0405763952294396	ITGA2/SYT11/CD36/GATA2	4
GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	4/988	16/18722	0.00842540736785991	0.0405763952294396	PARP9/DTX3L/KMT5B/RIF1	4
GO:2001224	positive regulation of neuron migration	4/988	16/18722	0.00842540736785991	0.0405763952294396	MDK/FLNA/RAPGEF2/NIPBL	4
GO:0060420	regulation of heart growth	10/988	79/18722	0.00846374545910298	0.0407241085858288	EDN1/IGF1/MEF2C/NOTCH1/TGFBR2/GJA1/DUSP6/PTEN/MAPK1/SAV1	10
GO:0030178	negative regulation of Wnt signaling pathway	17/988	170/18722	0.0085775544843847	0.0411970790425421	IGFBP4/TMEM88/FZD4/NXN/WWTR1/CAV1/NOTCH1/RBMS3/MDK/CTNND1/CYLD/EGR1/FZD6/CSNK1A1/APC/G3BP1/RNF213	17
GO:0043487	regulation of RNA stability	17/988	170/18722	0.0085775544843847	0.0411970790425421	VIM/ZFP36L1/PABPC1/ZFP36/TNRC6B/CELF1/CNOT6L/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/PUM2/ROCK2/TNRC6A/ROCK1/CNOT2/BTG2	17
GO:0034763	negative regulation of transmembrane transport	15/988	143/18722	0.0086007793710473	0.0412713098635983	CAV1/CLIC2/PRKCE/FABP5/THBS1/PEA15/CTTNBP2NL/CALM1/SESTD1/PTEN/SLC30A1/PKD2/CRBN/NEDD4/OAZ2	15
GO:0051924	regulation of calcium ion transport	23/988	255/18722	0.00872378824686954	0.0417048868165804	APLNR/RAMP3/F2R/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/PDGFB/GNAI2/SARAF/CALM1/PML/GJA1/FYN/SESTD1/STIM2/PDE4B/RHOA/TMBIM6/AHNAK/SLC30A1/PKD2	23
GO:0048008	platelet-derived growth factor receptor signaling pathway	8/988	56/18722	0.00874441423084964	0.0417048868165804	HIP1/TXNIP/NRP1/PDGFB/PTEN/PIK3C2A/CBLB/PTPN12	8
GO:0051058	negative regulation of small GTPase mediated signal transduction	8/988	56/18722	0.00874441423084964	0.0417048868165804	HEG1/CGNL1/RASIP1/RASA4/DLC1/ITGB1/TNFAIP1/PPP2CB	8
GO:0030835	negative regulation of actin filament depolymerization	7/988	45/18722	0.00874609260423016	0.0417048868165804	SPTBN1/SPTAN1/PIK3CA/TMOD3/RDX/ADD1/GSN	7
GO:0035307	positive regulation of protein dephosphorylation	7/988	45/18722	0.00874609260423016	0.0417048868165804	CDH5/ITGA1/DLC1/PPP2R5A/CALM1/TGFB1/PPP1R12A	7
GO:0048546	digestive tract morphogenesis	7/988	45/18722	0.00874609260423016	0.0417048868165804	HLX/FOXF1/NOTCH1/HIF1A/SMAD2/NIPBL/ID2	7
GO:0071364	cellular response to epidermal growth factor stimulus	7/988	45/18722	0.00874609260423016	0.0417048868165804	ID1/ZFP36L1/CFLAR/ZFP36/IQGAP1/ZFP36L2/PTPN12	7
GO:1903828	negative regulation of cellular protein localization	13/988	117/18722	0.00876641432427867	0.0417642985565635	ANGPT1/PPP2R5A/PKIG/MDFIC/TGFB1/GDI1/CD36/CTNNA1/PICALM/HECTD1/SP100/LEPROT/ROCK2	13
GO:1901990	regulation of mitotic cell cycle phase transition	26/988	299/18722	0.00877824195884167	0.0417831731947733	PLCB1/RGCC/ZFP36L1/KMT2E/APP/RB1/DUSP1/PML/TAOK1/CDC25B/TMOD3/KLF4/PTEN/RDX/CTDSP2/PKD2/APC/CCND1/ZFP36L2/CDC27/CTDSP1/WAC/RAB11A/FOXN3/ID2/PLK2	26
GO:0006658	phosphatidylserine metabolic process	5/988	25/18722	0.0089027922730984	0.0420370067152878	PLA1A/SERINC3/SERINC1/OSBPL10/PLSCR1	5
GO:0045324	late endosome to vacuole transport	5/988	25/18722	0.0089027922730984	0.0420370067152878	LEPROTL1/TMEM50B/LEPROT/TMEM50A/VPS36	5
GO:0062009	secondary palate development	5/988	25/18722	0.0089027922730984	0.0420370067152878	LRRC32/TSHZ1/TGFBR2/SMAD2/SMAD4	5
GO:0072207	metanephric epithelium development	5/988	25/18722	0.0089027922730984	0.0420370067152878	WWTR1/LAMB2/PKD2/ACAT1/HES1	5
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	5/988	25/18722	0.0089027922730984	0.0420370067152878	CAV1/PDE4D/CALM1/GJA1/GJA5	5
GO:0090330	regulation of platelet aggregation	5/988	25/18722	0.0089027922730984	0.0420370067152878	CEACAM1/SH2B3/IL6ST/CD9/F11R	5
GO:1903901	negative regulation of viral life cycle	5/988	25/18722	0.0089027922730984	0.0420370067152878	BST2/IFITM2/IFITM3/IFITM1/GSN	5
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	5/988	25/18722	0.0089027922730984	0.0420370067152878	SELP/ETS1/MDK/NFAT5/RHOA	5
GO:1905564	positive regulation of vascular endothelial cell proliferation	5/988	25/18722	0.0089027922730984	0.0420370067152878	FGFR1/IGF2/MDK/AKT3/STAT3	5
GO:0007612	learning	15/988	144/18722	0.00914764931320191	0.043091843496081	CLDN5/TANC1/SYT11/ITGB1/GIT1/APP/FYN/ACTR2/HIF1A/CREB1/NPTN/UBA6/PIAS1/BTG2/JUN	15
GO:0043433	negative regulation of DNA-binding transcription factor activity	18/988	185/18722	0.00916204908398836	0.043091843496081	ID3/ID1/TMSB4X/RB1/CD200/TAX1BP1/CARD8/KLF4/EGLN1/FLNA/PURA/CYLD/PKD2/FZD6/SP100/HES1/ID2/BHLHE40	18
GO:0150063	visual system development	31/988	375/18722	0.00918076612316055	0.043091843496081	VIM/ACVRL1/RHOJ/FZD4/ARHGEF15/COL4A1/BMPR2/JAG1/TSPAN12/LAMB2/TGFBR2/SKIL/CRYBG3/NRP1/HIPK2/GNB1/KLF4/TUG1/ABI2/HIF1A/SKI/PTPRM/PHACTR4/STAT3/CLIC4/ATP2B4/HIPK1/EFEMP1/ATF6/NIPBL/SOS1	31
GO:0034394	protein localization to cell surface	9/988	68/18722	0.00918297568478232	0.043091843496081	ANGPT1/JAM3/STX3/FLNA/VCL/EMP2/PICALM/LEPROT/RAB11A	9
GO:0042267	natural killer cell mediated cytotoxicity	9/988	68/18722	0.00918297568478232	0.043091843496081	CEACAM1/HLA-E/HLA-A/HLA-B/KIF5B/LYST/LAMP1/RAB27A/CRK	9
GO:0042987	amyloid precursor protein catabolic process	9/988	68/18722	0.00918297568478232	0.043091843496081	IGF1/FKBP1A/CLU/ADAM10/RTN4/PICALM/ROCK2/DYRK1A/ROCK1	9
GO:1902305	regulation of sodium ion transmembrane transport	9/988	68/18722	0.00918297568478232	0.043091843496081	PRKCE/UTRN/KIF5B/STOM/ACTN4/FXYD5/ATP2B4/WNK1/NEDD4	9
GO:0046640	regulation of alpha-beta T cell proliferation	6/988	35/18722	0.00927747208476165	0.0434584935751798	HLA-E/HLA-A/TGFBR2/CD81/TNFRSF14/CBLB	6
GO:2000403	positive regulation of lymphocyte migration	6/988	35/18722	0.00927747208476165	0.0434584935751798	JAM2/APP/TNFRSF14/RHOA/ADAM10/WNK1	6
GO:0043488	regulation of mRNA stability	16/988	158/18722	0.00942364992138936	0.0441043421871544	VIM/ZFP36L1/PABPC1/ZFP36/TNRC6B/CELF1/CNOT6L/RC3H1/ZFP36L2/CNOT8/PUM2/ROCK2/TNRC6A/ROCK1/CNOT2/BTG2	16
GO:0002764	immune response-regulating signaling pathway	37/988	468/18722	0.00946506132167204	0.0442591599830298	FCGR2B/CEACAM1/MEF2C/CAV1/PDE4D/FOXP1/PRKCE/HLA-A/SEC14L1/RPS6KA3/CD81/DDX60/TSPAN6/XIAP/YES1/PRKCH/FYN/PIK3CA/PDE4B/CD36/CMTM3/CYLD/RTN4/WDFY1/PLSCR1/RC3H1/PJA2/PAK2/CBLB/WNK1/PUM2/PTK2/SOS1/HSPA1A/MAPK1/BCL10/RAP1A	37
GO:0099003	vesicle-mediated transport in synapse	19/988	200/18722	0.00965590312121489	0.0451118358662212	P2RY1/SYT11/CANX/GIT1/CALM1/ITSN2/STX3/AP2B1/PTEN/KIAA1109/SNAP23/PPP3R1/PICALM/CTBP2/RAB11A/CLCN3/ROCK1/RAB5A/RAP1A	19
GO:0034205	amyloid-beta formation	8/988	57/18722	0.00971433085123729	0.0453449257309073	IGF1/CLU/ADAM10/RTN4/PICALM/ROCK2/DYRK1A/ROCK1	8
GO:1901992	positive regulation of mitotic cell cycle phase transition	11/988	93/18722	0.00975423913641873	0.0454513318356634	PLCB1/RGCC/KMT2E/APP/RB1/CDC25B/TMOD3/RDX/CCND1/CDC27/RAB11A	11
GO:1902807	negative regulation of cell cycle G1/S phase transition	11/988	93/18722	0.00975423913641873	0.0454513318356634	RB1/PML/KLF4/PTEN/CTDSP2/PKD2/APC/CCND1/CTDSP1/WAC/PLK2	11
GO:0060976	coronary vasculature development	7/988	46/18722	0.00985800002000061	0.0458945627574437	APLNR/PLXND1/SMAD6/NOTCH1/NRP1/AP2B1/ADAMTS6	7
GO:0071356	cellular response to tumor necrosis factor	21/988	229/18722	0.00992730090141295	0.0461767271351187	EDN1/FABP4/PLVAP/CRHBP/HYAL2/KLF2/THBS1/TMSB4X/ZFP36L1/ACTN4/CARD16/LIMS1/CARD8/TNFRSF14/ZFP36/CYLD/HIPK1/TNFRSF1B/ZFP36L2/HSPA1A/MAPK1	21
GO:0001824	blastocyst development	12/988	106/18722	0.0100052529478945	0.0464173831084854	IGF1/LPAR6/SKIL/MFNG/BCOR/N4BP2L2/KLF4/GABPA/CAPN2/CMTM3/RTN4/CNOT2	12
GO:0019882	antigen processing and presentation	12/988	106/18722	0.0100052529478945	0.0464173831084854	FCGR2B/HLA-E/HLA-A/THBS1/HLA-B/HLA-C/B2M/ERAP1/RAB27A/PSMB8/LNPEP/TAPBP	12
GO:2000278	regulation of DNA biosynthetic process	12/988	106/18722	0.0100052529478945	0.0464173831084854	ACVRL1/DACH1/BMPR2/RGCC/PDGFB/DUSP1/GJA1/HMBOX1/KLF4/NEK7/MAPK1/XRN1	12
GO:0014032	neural crest cell development	10/988	81/18722	0.0100455352269301	0.0464824765901157	EDN1/FN1/JAG1/NRP1/EFNB1/HIF1A/PHACTR4/SEMA3F/HES1/MAPK1	10
GO:0048708	astrocyte differentiation	10/988	81/18722	0.0100455352269301	0.0464824765901157	VIM/LAMB2/NOTCH1/APP/CDK6/IL6ST/STAT3/HES1/MAPK1/ID2	10
GO:0060968	regulation of gene silencing	10/988	81/18722	0.0100455352269301	0.0464824765901157	TGFB1/ZFP36/STAT3/TNRC6B/ADAR/PPP3CA/ATF7IP/PUM2/DDX6/ZMPSTE24	10
GO:1901224	positive regulation of NIK/NF-kappaB signaling	9/988	69/18722	0.0100801865605534	0.0466022201998776	EDN1/ACTN4/SASH1/APP/LIMS1/NFAT5/RHOA/EIF2AK2/RC3H1	9
GO:0010469	regulation of signaling receptor activity	17/988	173/18722	0.0101280497102463	0.0467827826615898	FCGR2B/EDN1/CRHBP/RAMP3/P2RY1/BICD1/MEF2C/PDE4D/ITGB1/NRP1/APP/SHC1/PTEN/HIF1A/SOCS4/DLGAP4/CBLB	17
GO:0061136	regulation of proteasomal protein catabolic process	18/988	187/18722	0.0101799379254585	0.0469816075239232	CAV1/CLU/RNF144B/TRIB2/ATXN3/RNF19A/OGT/RYBP/SDCBP/CSNK1A1/HECTD1/SOCS4/WAC/HSPA1A/XPO1/PIAS1/PLK2/TMTC3	18
GO:0042542	response to hydrogen peroxide	15/988	146/18722	0.0103237925286583	0.0476041544377021	FOXO1/ETS1/KLF2/TXNIP/RHOB/PCGF2/DUSP1/FYN/KLF4/CAPN2/SETX/PPP2CB/PRKAA1/CRK/JUN	15
GO:0099177	regulation of trans-synaptic signaling	35/988	440/18722	0.0104301928693459	0.0480487797452834	EDN1/P2RY1/PLCB4/LAMA2/MEF2C/SYT11/PLCB1/SRGN/PRKCE/FABP5/ITGB1/KIF5B/GIT1/APP/GNAI2/SLC12A2/CALM1/STX3/FYN/PTEN/RNF19A/CREB1/STAT3/SLC30A1/NPTN/RAPGEF2/PPP3R1/PPP3CA/DLGAP4/PTPRA/RAB11A/MAPK1/PLK2/RAB5A/RAP1A	35
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	11/988	94/18722	0.0105365628870862	0.0480487797452834	HHEX/RGCC/PDGFB/CCNY/PTEN/NR2F2/PKD2/APC/CCND1/CCNI/CCNT1	11
GO:0001738	morphogenesis of a polarized epithelium	11/988	94/18722	0.0105365628870862	0.0480487797452834	RSPO3/TCF15/FOXF1/MSN/SMURF2/EXOC5/RHOA/FZD6/MYO9A/DAAM1/CDC42	11
GO:0061326	renal tubule development	11/988	94/18722	0.0105365628870862	0.0480487797452834	DCHS1/WWTR1/MEF2C/COL4A1/JAG1/NOTCH1/PKD2/ACAT1/HES1/SMAD4/MTSS1	11
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	5/988	26/18722	0.0105534350424207	0.0480487797452834	FOXP1/CD81/PRKCH/CMTM3/BCL10	5
GO:0050926	regulation of positive chemotaxis	5/988	26/18722	0.0105534350424207	0.0480487797452834	KDR/S1PR1/VEGFC/ITGA2/ANGPT2	5
GO:0060037	pharyngeal system development	5/988	26/18722	0.0105534350424207	0.0480487797452834	ADGRF5/ECE1/BMPR2/PLXNA2/HES1	5
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	5/988	26/18722	0.0105534350424207	0.0480487797452834	PDE4D/CLIC2/FKBP1A/CALM1/PKD2	5
GO:0003184	pulmonary valve morphogenesis	4/988	17/18722	0.0105649425343545	0.0480487797452834	SMAD6/JAG1/NOTCH1/GJA5	4
GO:0035518	histone H2A monoubiquitination	4/988	17/18722	0.0105649425343545	0.0480487797452834	PCGF2/BCOR/RYBP/PCGF5	4
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	4/988	17/18722	0.0105649425343545	0.0480487797452834	PIK3R3/PIK3CA/PIK3C2B/PIK3C2A	4
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4/988	17/18722	0.0105649425343545	0.0480487797452834	CAV1/SH2B3/SOCS3/PARP14	4
GO:0044539	long-chain fatty acid import into cell	4/988	17/18722	0.0105649425343545	0.0480487797452834	THBS1/ACSL3/CD36/SLC2A1	4
GO:0055119	relaxation of cardiac muscle	4/988	17/18722	0.0105649425343545	0.0480487797452834	PDE4D/PIK3CA/PDE4B/GSN	4
GO:0061158	3'-UTR-mediated mRNA destabilization	4/988	17/18722	0.0105649425343545	0.0480487797452834	ZFP36L1/ZFP36/RC3H1/ZFP36L2	4
GO:0140354	lipid import into cell	4/988	17/18722	0.0105649425343545	0.0480487797452834	THBS1/ACSL3/CD36/SLC2A1	4
GO:0002691	regulation of cellular extravasation	6/988	36/18722	0.0106477612188648	0.0482601600636602	PLVAP/SELP/IL1R1/PLCB1/MDK/JAM3	6
GO:0003230	cardiac atrium development	6/988	36/18722	0.0106477612188648	0.0482601600636602	HEG1/ENG/BMPR2/NOTCH1/GJA5/SOS1	6
GO:0030224	monocyte differentiation	6/988	36/18722	0.0106477612188648	0.0482601600636602	FOXP1/IFI16/ZFP36L1/CDK6/MYH9/JUN	6
GO:0060251	regulation of glial cell proliferation	6/988	36/18722	0.0106477612188648	0.0482601600636602	NOTCH1/DICER1/PRKCH/SKI/CREB1/HES1	6
GO:0030308	negative regulation of cell growth	18/988	188/18722	0.0107216443064235	0.0485294088551128	MEG3/BST2/ACVRL1/NPR1/HYAL2/BMPR2/ADAM15/CCDC85B/NRP1/RB1/PML/TGFB1/GJA1/SEMA3F/RTN4/SPAG9/HSPA1A/SMAD4	18
GO:0071774	response to fibroblast growth factor	13/988	120/18722	0.0107437723909729	0.0485294088551128	KL/NDNF/HYAL2/FGFR1/THBS1/ZFP36L1/SULF2/SETX/ZFP36/NPTN/CD44/ZFP36L2/SHOC2	13
GO:0010927	cellular component assembly involved in morphogenesis	12/988	107/18722	0.0107452024545865	0.0485294088551128	EDN1/ITGB1/PHLDB2/MEF2A/DICER1/CFLAR/PRKAR1A/TMOD3/MFSD14A/CD9/PLEC/SMAD4	12
GO:0021761	limbic system development	12/988	107/18722	0.0107452024545865	0.0485294088551128	NDNF/ETS1/NRP1/KIF5B/CDK6/MDK/PTEN/TBX3/ATP2B4/CRK/UBA6/BTG2	12
GO:0045604	regulation of epidermal cell differentiation	8/988	58/18722	0.0107619811052942	0.0485294088551128	CD109/NOTCH1/ZFP36L1/PRKCH/ZFP36/HES1/ROCK2/ROCK1	8
GO:2000649	regulation of sodium ion transmembrane transporter activity	8/988	58/18722	0.0107619811052942	0.0485294088551128	PRKCE/UTRN/KIF5B/STOM/ACTN4/FXYD5/WNK1/NEDD4	8
GO:0007204	positive regulation of cytosolic calcium ion concentration	27/988	319/18722	0.0107722219472677	0.0485343876029569	APLNR/EDN1/LRP6/S1PR1/RAMP3/P2RY1/F2R/LPAR6/CAV1/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/PML/GJA1/GNB1/FYN/ERO1A/ITPR2/CD36/TMBIM6/GATA2/NPTN/PKD2/ATP2B4	27
GO:0043242	negative regulation of protein-containing complex disassembly	10/988	82/18722	0.0109161942000535	0.0490997659531617	SPTBN1/SPTAN1/TAOK1/PIK3CA/TMOD3/RDX/ADD1/APC/GSN/CAMSAP2	10
GO:0046889	positive regulation of lipid biosynthetic process	10/988	82/18722	0.0109161942000535	0.0490997659531617	ADGRF5/ZBTB20/SCARB1/LPGAT1/ACSL3/CAPN2/ELOVL5/CREB1/STARD4/PRKAA1	10
GO:0016574	histone ubiquitination	7/988	47/18722	0.0110695272196347	0.0497052650808958	PCGF2/BCOR/RYBP/PCGF5/WAC/DTX3L/TRIP12	7
GO:0072583	clathrin-dependent endocytosis	7/988	47/18722	0.0110695272196347	0.0497052650808958	HIP1/SYT11/CANX/ITSN2/AP2B1/PICALM/WASL	7
GO:0051650	establishment of vesicle localization	16/988	161/18722	0.0111767787706674	0.0501444669170482	EXOC6/SYT11/MAP4K2/KIF5B/ACTN4/RAB27A/SNAP23/MYO1C/PICALM/WDR11/RAB11A/FAM91A1/DYNC1H1/WASL/KIFAP3/STARD3NL	16
GO:0048880	sensory system development	31/988	381/18722	0.0113621740579964	0.050864993277223	VIM/ACVRL1/RHOJ/FZD4/ARHGEF15/COL4A1/BMPR2/JAG1/TSPAN12/LAMB2/TGFBR2/SKIL/CRYBG3/NRP1/HIPK2/GNB1/KLF4/TUG1/ABI2/HIF1A/SKI/PTPRM/PHACTR4/STAT3/CLIC4/ATP2B4/HIPK1/EFEMP1/ATF6/NIPBL/SOS1	31
GO:0042982	amyloid precursor protein metabolic process	11/988	95/18722	0.0113661044841987	0.050864993277223	IGF1/ITM2A/FKBP1A/ITM2B/CLU/ADAM10/RTN4/PICALM/ROCK2/DYRK1A/ROCK1	11
GO:0050764	regulation of phagocytosis	11/988	95/18722	0.0113661044841987	0.050864993277223	FCGR2B/ITGA2/SCARB1/SYT11/PTEN/CD36/RAB27A/DYSF/GATA2/PLSCR1/RAP1A	11
GO:0006402	mRNA catabolic process	21/988	232/18722	0.0114014515596013	0.0509802278489918	VIM/ZFP36L1/PABPC1/ZFP36/CSDE1/TNRC6B/CELF1/CNOT6L/ZC3HAV1/RC3H1/ZFP36L2/CNOT8/PUM2/ROCK2/SMG1/TNRC6A/ROCK1/CNOT2/HSPA1A/XRN1/BTG2	21
GO:0043244	regulation of protein-containing complex disassembly	13/988	121/18722	0.0114746692721634	0.0512644601965786	SPTBN1/SPTAN1/TAOK1/PIK3CA/TMOD3/SETX/RDX/ADD1/APC/GSN/DSTN/CAMSAP2/ZMPSTE24	13
GO:0051384	response to glucocorticoid	15/988	148/18722	0.0116158500863791	0.0518080568084347	SPARC/EDN1/FOXO1/PAM/IGFBP7/ZFP36L1/MDK/CALM1/DUSP1/CFLAR/RHOA/ZFP36/CCND1/ZFP36L2/NR3C1	15
GO:2001056	positive regulation of cysteine-type endopeptidase activity	15/988	148/18722	0.0116158500863791	0.0518080568084347	SOX7/F2R/UACA/TNFSF10/HIP1/DLC1/PPM1F/IFI16/PML/CFLAR/FYN/CARD8/RHOA/GSN/BCL10	15
GO:0060759	regulation of response to cytokine stimulus	16/988	162/18722	0.0118150426302485	0.0526522705133222	EDN1/CAV1/IL1R1/ANGPT1/SH2B3/CARD16/CARD8/KLF4/PARP14/ISG15/HIF1A/CYLD/ADAR/PARP9/HIPK1/HSPA1A	16
GO:0030042	actin filament depolymerization	8/988	59/18722	0.0118908666723281	0.0528571412246083	SPTBN1/SPTAN1/PIK3CA/TMOD3/RDX/ADD1/GSN/DSTN	8
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	8/988	59/18722	0.0118908666723281	0.0528571412246083	HYAL2/CAV1/SH3BP5/SH2B3/SOCS3/PARP14/SOCS4/CBLB	8
GO:0051568	histone H3-K4 methylation	8/988	59/18722	0.0118908666723281	0.0528571412246083	NNMT/BCOR/KMT2E/KMT2A/OGT/ASH1L/WDR82/SMAD4	8
GO:0062197	cellular response to chemical stress	28/988	337/18722	0.0120422241763738	0.0534851963418875	LRRC8C/CAV1/FOXO1/EPAS1/ETS1/KLF2/RHOB/PCGF2/PXN/ZFP36L1/PML/FYN/TP53INP1/PIK3CA/KLF4/NCOA7/SETX/CD36/HIF1A/PKD2/SLC2A1/PRKAA1/PLEC/ATF2/HSPA1A/MAPK1/JUN/NFE2L1	28
GO:0002228	natural killer cell mediated immunity	9/988	71/18722	0.0120705044667397	0.0535652510045101	CEACAM1/HLA-E/HLA-A/HLA-B/KIF5B/LYST/LAMP1/RAB27A/CRK	9
GO:0043010	camera-type eye development	27/988	322/18722	0.0120804161715744	0.0535652510045101	VIM/ACVRL1/RHOJ/FZD4/ARHGEF15/COL4A1/BMPR2/JAG1/TSPAN12/LAMB2/TGFBR2/SKIL/CRYBG3/NRP1/HIPK2/GNB1/KLF4/ABI2/HIF1A/SKI/PTPRM/PHACTR4/CLIC4/ATP2B4/HIPK1/EFEMP1/SOS1	27
GO:0001990	regulation of systemic arterial blood pressure by hormone	6/988	37/18722	0.0121554374123335	0.0536293052610594	EDN1/ECE1/F2R/RPS6KA2/PCSK5/RHOA	6
GO:0014904	myotube cell development	6/988	37/18722	0.0121554374123335	0.0536293052610594	IGF1/CAV2/RCAN1/SKI/PPP3CA/PLEC	6
GO:0033363	secretory granule organization	6/988	37/18722	0.0121554374123335	0.0536293052610594	F2R/SRGN/LYST/CREB1/MFSD14A/ABCA1	6
GO:0043403	skeletal muscle tissue regeneration	6/988	37/18722	0.0121554374123335	0.0536293052610594	IGF1/TGFBR2/CD81/CFLAR/CD9/PPP3CA	6
GO:0048009	insulin-like growth factor receptor signaling pathway	6/988	37/18722	0.0121554374123335	0.0536293052610594	IGFBP4/IGF1/PLCB1/CRIM1/IGFBP3/PHIP	6
GO:0090218	positive regulation of lipid kinase activity	6/988	37/18722	0.0121554374123335	0.0536293052610594	TEK/CD81/PDGFB/TGFB1/CDC42/PTK2	6
GO:0006644	phospholipid metabolic process	31/988	383/18722	0.0121769381756582	0.0536795814017397	ADGRF5/PLA1A/ENPP2/PLPP1/SCARB1/PLCB1/FABP5/SPTLC2/DGKH/SERINC3/PIK3R3/PDGFB/SERINC1/OSBPL10/SOCS3/PLPP3/LPGAT1/PIK3CA/PIK3C2B/ACSL3/PTEN/CAPN2/SLC44A2/MTMR6/SLC44A1/PIK3C2A/PLSCR1/SOCS4/SMG1/FAR1/ETNK1	31
GO:0035282	segmentation	11/988	96/18722	0.0122446103046292	0.0539331425689802	MEOX2/LRP6/TCF15/FOXF1/NOTCH1/NRP1/PLXNA2/MIB1/SEMA3F/TBX3/SMAD4	11
GO:0090311	regulation of protein deacetylation	7/988	48/18722	0.0123853959977786	0.0543992114517102	APLNR/NNMT/FRY/SKI/PRKAA1/NIPBL/DYRK1A	7
GO:0097720	calcineurin-mediated signaling	7/988	48/18722	0.0123853959977786	0.0543992114517102	IGF1/LMCD1/RCAN1/NFAT5/PPP3R1/ATP2B4/PPP3CA	7
GO:0007263	nitric oxide mediated signal transduction	5/988	27/18722	0.0124016274600943	0.0543992114517102	NDNF/THBS1/DDAH2/CD36/ATP2B4	5
GO:0010758	regulation of macrophage chemotaxis	5/988	27/18722	0.0124016274600943	0.0543992114517102	MTUS1/THBS1/MDK/PTK2/MAPK1	5
GO:0048873	homeostasis of number of cells within a tissue	5/988	27/18722	0.0124016274600943	0.0543992114517102	F2R/NOTCH1/AKT3/GATA2/LIPA	5
GO:0051480	regulation of cytosolic calcium ion concentration	29/988	353/18722	0.0124125654665474	0.0544022671273103	APLNR/EDN1/LRP6/S1PR1/RAMP3/P2RY1/F2R/LPAR6/CAV1/CAV2/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/PML/GJA1/GNB1/FYN/GTF2I/ERO1A/ITPR2/CD36/TMBIM6/GATA2/NPTN/PKD2/ATP2B4	29
GO:0006401	RNA catabolic process	24/988	278/18722	0.012469330279093	0.054606003662442	VIM/ZFP36L1/DICER1/PABPC1/OAS2/ZFP36/CSDE1/TNRC6B/CELF1/CNOT6L/ZC3HAV1/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/PUM2/ROCK2/SMG1/TNRC6A/ROCK1/CNOT2/HSPA1A/XRN1/BTG2	24
GO:0050821	protein stabilization	18/988	191/18722	0.0124854311758456	0.0546314747990873	IGF1/TMEM88/HIP1/CLU/GNAQ/CTNND1/PLPP3/LAMP1/PTEN/SEL1L/FLNA/CREB1/RTN4/ATF7IP/CRTAP/HSPA1A/GOLGA7/SAV1	18
GO:0043405	regulation of MAP kinase activity	17/988	177/18722	0.0125329806206797	0.0547493363956009	EDN1/FZD4/HYAL2/CAV1/FGFR1/THBS1/MAP4K2/SH2B3/PDGFB/SASH1/DUSP1/AIDA/TGFB1/MAP3K11/TRIB2/HIPK3/IQGAP1	17
GO:0051648	vesicle localization	17/988	177/18722	0.0125329806206797	0.0547493363956009	EXOC6/SYT11/MAP4K2/KIF5B/ACTN4/PTEN/RAB27A/SNAP23/MYO1C/PICALM/WDR11/RAB11A/FAM91A1/DYNC1H1/WASL/KIFAP3/STARD3NL	17
GO:1900180	regulation of protein localization to nucleus	14/988	136/18722	0.0127315431955509	0.0555254166295289	HYAL2/WWTR1/ANGPT1/PKIG/MDFIC/TGFB1/FYN/FLNA/CD36/FERMT2/PARP9/CTNNA1/DTX3L/MAPK1	14
GO:1903305	regulation of regulated secretory pathway	14/988	136/18722	0.0127315431955509	0.0555254166295289	FCGR2B/P2RY1/CEACAM1/FOXF1/SYT11/NOTCH1/GIT1/GNAI2/CALM1/LAMP1/RAB27A/GATA2/RAB5A/RAP1A	14
GO:0031503	protein-containing complex localization	20/988	220/18722	0.0127458009388317	0.0555419972002246	HHEX/HIP1/KIF5B/STX3/AP2B1/PURA/RALB/ZC3H11A/ADAM10/PCM1/NPTN/PPP3R1/FYTTD1/THOC2/RAB11A/SMG1/WASL/SYNJ2BP/XPO1/RAP1A	20
GO:0042310	vasoconstriction	10/988	84/18722	0.0128277357047016	0.0556182096032575	EDN1/ECE1/F2R/CAV1/BMPR2/DOCK4/GJA1/RHOA/PIK3C2A/GJA5	10
GO:1900542	regulation of purine nucleotide metabolic process	10/988	84/18722	0.0128277357047016	0.0556182096032575	IGF1/ZBTB20/TMSB4X/GIT1/PDK4/APP/HIF1A/OGT/STAT3/PRKAA1	10
GO:0017038	protein import	19/988	206/18722	0.0129649824289217	0.0556182096032575	HYAL2/TXNIP/ANGPT1/NOTCH1/CLU/PKIG/MDFIC/IPO11/PML/TGFB1/KPNA3/FLNA/CD36/RANBP2/STAT3/PPP3R1/PPP3CA/CBLB/MAPK1	19
GO:0002263	cell activation involved in immune response	24/988	279/18722	0.0129853599620324	0.0556182096032575	FCGR2B/HLX/CEACAM1/FOXF1/ITM2A/FOXP1/PRKCE/MFNG/CD81/LGALS1/APP/MDK/TGFB1/LAMP1/RAB27A/DYSF/STAT3/GATA2/SNAP23/RC3H1/S100A13/CD46/KMT5B/RIF1	24
GO:0043217	myelin maintenance	4/988	18/18722	0.013026278104113	0.0556182096032575	CLU/PTEN/NDRG1/PLEC	4
GO:0048268	clathrin coat assembly	4/988	18/18722	0.013026278104113	0.0556182096032575	HIP1/AP2B1/PIK3C2A/PICALM	4
GO:0060749	mammary gland alveolus development	4/988	18/18722	0.013026278104113	0.0556182096032575	FOXF1/HIF1A/CCND1/ID2	4
GO:0061377	mammary gland lobule development	4/988	18/18722	0.013026278104113	0.0556182096032575	FOXF1/HIF1A/CCND1/ID2	4
GO:0071071	regulation of phospholipid biosynthetic process	4/988	18/18722	0.013026278104113	0.0556182096032575	ADGRF5/PDGFB/ACSL3/CAPN2	4
GO:0071800	podosome assembly	4/988	18/18722	0.013026278104113	0.0556182096032575	FSCN1/MSN/RHOA/GSN	4
GO:0072234	metanephric nephron tubule development	4/988	18/18722	0.013026278104113	0.0556182096032575	WWTR1/PKD2/ACAT1/HES1	4
GO:0080182	histone H3-K4 trimethylation	4/988	18/18722	0.013026278104113	0.0556182096032575	KMT2E/KMT2A/OGT/WDR82	4
GO:0150079	negative regulation of neuroinflammatory response	4/988	18/18722	0.013026278104113	0.0556182096032575	IGF1/SYT11/CD200/TNFRSF1B	4
GO:1902001	fatty acid transmembrane transport	4/988	18/18722	0.013026278104113	0.0556182096032575	THBS1/CPT1A/CD36/SLC2A1	4
GO:0001959	regulation of cytokine-mediated signaling pathway	15/988	150/18722	0.0130311701519672	0.0556182096032575	EDN1/CAV1/IL1R1/ANGPT1/SH2B3/CARD16/CARD8/PARP14/ISG15/HIF1A/CYLD/ADAR/PARP9/HIPK1/HSPA1A	15
GO:0070665	positive regulation of leukocyte proliferation	15/988	150/18722	0.0130311701519672	0.0556182096032575	BST2/IGF1/MEF2C/HLA-E/HLA-A/TGFBR2/IGF2/CD81/EFNB1/IL6ST/CD320/CD46/HES1/PTK2/MAPK1	15
GO:0051604	protein maturation	25/988	294/18722	0.0130410078529834	0.0556182096032575	CPE/ECE1/NNAT/CLEC3B/RPS6KA2/PCSK5/FKBP1A/SRGN/TSPAN14/THBS1/IFI16/CARD16/XIAP/SPCS3/CPD/MYH9/CARD8/SERPINH1/CAPN2/ERO1A/OGT/ADAM10/FAM111A/GSN/ZMPSTE24	25
GO:0045930	negative regulation of mitotic cell cycle	21/988	235/18722	0.0130458350904269	0.0556182096032575	RGCC/ZFP36L1/RB1/DUSP1/PML/TGFB1/TAOK1/KLF4/PTEN/CTDSP2/PKD2/APC/HECA/CCND1/ZFP36L2/CTDSP1/WAC/ATF2/FOXN3/BTG2/PLK2	21
GO:0006893	Golgi to plasma membrane transport	8/988	60/18722	0.0131044597188637	0.0556182096032575	SPTBN1/STXBP6/EXOC6/MACF1/VAMP5/EXOC5/ACSL3/GOLGA7	8
GO:0031102	neuron projection regeneration	8/988	60/18722	0.0131044597188637	0.0556182096032575	SCARF1/LAMB2/JAM3/KLF4/PTEN/FLNA/MAP4K4/CTNNA1	8
GO:0042306	regulation of protein import into nucleus	8/988	60/18722	0.0131044597188637	0.0556182096032575	HYAL2/ANGPT1/PKIG/MDFIC/TGFB1/FLNA/CD36/MAPK1	8
GO:0001707	mesoderm formation	9/988	72/18722	0.0131689854597629	0.0556182096032575	FOXF1/ITGA2/BMPR2/ITGB1/SMAD1/GJA1/PRKAR1A/KLF4/SMAD2	9
GO:0030330	DNA damage response, signal transduction by p53 class mediator	9/988	72/18722	0.0131689854597629	0.0556182096032575	HIPK2/PML/ATRX/NDRG1/CD44/SP100/DYRK1A/PLK2/ZMPSTE24	9
GO:0043903	regulation of biological process involved in symbiotic interaction	9/988	72/18722	0.0131689854597629	0.0556182096032575	CAV1/IFITM2/CAV2/IFITM3/IFITM1/LGALS1/PML/TRIM13/GSN	9
GO:0055021	regulation of cardiac muscle tissue growth	9/988	72/18722	0.0131689854597629	0.0556182096032575	EDN1/IGF1/MEF2C/NOTCH1/TGFBR2/GJA1/PTEN/MAPK1/SAV1	9
GO:0014909	smooth muscle cell migration	11/988	97/18722	0.0131738289796861	0.0556182096032575	IGF1/ITGA2/MEF2C/DOCK4/NRP1/PDGFB/MDK/IGFBP3/RHOA/IQGAP1/CRK	11
GO:0070252	actin-mediated cell contraction	11/988	97/18722	0.0131738289796861	0.0556182096032575	CAV1/PDE4D/LIMCH1/GJA1/PIK3CA/PDE4B/FLNA/EMP2/GJA5/GSN/MYL6	11
GO:0014812	muscle cell migration	12/988	110/18722	0.0132201420506834	0.0556182096032575	IGF1/ITGA2/MEF2C/DOCK4/NRP1/PDGFB/MDK/IGFBP3/RHOA/IQGAP1/CRK/ROCK1	12
GO:0032611	interleukin-1 beta production	12/988	110/18722	0.0132201420506834	0.0556182096032575	IGF1/F2R/FOXP1/IFI16/GIT1/CARD16/APP/PML/CARD8/CD36/STAT3/EGR1	12
GO:0032651	regulation of interleukin-1 beta production	12/988	110/18722	0.0132201420506834	0.0556182096032575	IGF1/F2R/FOXP1/IFI16/GIT1/CARD16/APP/PML/CARD8/CD36/STAT3/EGR1	12
GO:0048259	regulation of receptor-mediated endocytosis	12/988	110/18722	0.0132201420506834	0.0556182096032575	BICD1/HIP1/SYT11/ANGPT1/CLU/B2M/SDCBP/MKLN1/PPP3R1/PICALM/WASL/HNRNPK	12
GO:0003330	regulation of extracellular matrix constituent secretion	3/988	10/18722	0.013297275262827	0.0556182096032575	NOTCH1/RGCC/TNFRSF1B	3
GO:0007028	cytoplasm organization	3/988	10/18722	0.013297275262827	0.0556182096032575	KIF5B/ZMIZ1/SOS1	3
GO:0010944	negative regulation of transcription by competitive promoter binding	3/988	10/18722	0.013297275262827	0.0556182096032575	DACH1/HHEX/CREB1	3
GO:0010968	regulation of microtubule nucleation	3/988	10/18722	0.013297275262827	0.0556182096032575	GIT1/ARHGEF7/HSPA1A	3
GO:0015911	long-chain fatty acid import across plasma membrane	3/988	10/18722	0.013297275262827	0.0556182096032575	THBS1/CD36/SLC2A1	3
GO:0030214	hyaluronan catabolic process	3/988	10/18722	0.013297275262827	0.0556182096032575	HYAL2/TGFB1/CD44	3
GO:0035376	sterol import	3/988	10/18722	0.013297275262827	0.0556182096032575	SCARB1/CD36/STARD4	3
GO:0036363	transforming growth factor beta activation	3/988	10/18722	0.013297275262827	0.0556182096032575	LRRC32/LTBP1/LTBP3	3
GO:0042989	sequestering of actin monomers	3/988	10/18722	0.013297275262827	0.0556182096032575	TMSB4X/TMSB10/GSN	3
GO:0045792	negative regulation of cell size	3/988	10/18722	0.013297275262827	0.0556182096032575	PTEN/RDX/RHOA	3
GO:0045898	regulation of RNA polymerase II transcription preinitiation complex assembly	3/988	10/18722	0.013297275262827	0.0556182096032575	THRA/CREB1/ATF7IP	3
GO:0070099	regulation of chemokine-mediated signaling pathway	3/988	10/18722	0.013297275262827	0.0556182096032575	EDN1/SH2B3/HIF1A	3
GO:0070508	cholesterol import	3/988	10/18722	0.013297275262827	0.0556182096032575	SCARB1/CD36/STARD4	3
GO:0071073	positive regulation of phospholipid biosynthetic process	3/988	10/18722	0.013297275262827	0.0556182096032575	ADGRF5/ACSL3/CAPN2	3
GO:0071803	positive regulation of podosome assembly	3/988	10/18722	0.013297275262827	0.0556182096032575	FSCN1/MSN/RHOA	3
GO:0072124	regulation of glomerular mesangial cell proliferation	3/988	10/18722	0.013297275262827	0.0556182096032575	PDGFB/CFLAR/EGR1	3
GO:0150172	regulation of phosphatidylcholine metabolic process	3/988	10/18722	0.013297275262827	0.0556182096032575	SCARB1/ACSL3/CAPN2	3
GO:1901203	positive regulation of extracellular matrix assembly	3/988	10/18722	0.013297275262827	0.0556182096032575	RGCC/PHLDB2/TGFB1	3
GO:1905651	regulation of artery morphogenesis	3/988	10/18722	0.013297275262827	0.0556182096032575	NOTCH1/MDK/AKT3	3
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	3/988	10/18722	0.013297275262827	0.0556182096032575	NCKAP1/ABI2/WASL	3
GO:0045471	response to ethanol	14/988	137/18722	0.0135158496832989	0.0564879571342908	SPARC/CLDN5/CRHBP/PRKCE/CPT1A/FYN/TP53INP1/PTEN/ITPR2/ACTR2/RHOA/STAT3/CCND1/PRKAA1	14
GO:0060326	cell chemotaxis	26/988	310/18722	0.0135574403765184	0.0566172352830705	EDN1/KDR/S1PR1/VEGFC/MTUS1/FGFR1/ITGA1/THBS1/NOTCH1/DOCK4/TMSB4X/NRP1/PDGFB/MDK/SLC12A2/DUSP1/JAM3/LYST/PDE4B/ADAM10/MOSPD2/CRK/PLEC/WNK1/PTK2/MAPK1	26
GO:0035886	vascular associated smooth muscle cell differentiation	6/988	38/18722	0.0138070705591761	0.0572677737131156	APLNR/RAMP2/ENG/NOTCH1/PDGFB/HES1	6
GO:0046633	alpha-beta T cell proliferation	6/988	38/18722	0.0138070705591761	0.0572677737131156	HLA-E/HLA-A/TGFBR2/CD81/TNFRSF14/CBLB	6
GO:0097242	amyloid-beta clearance	6/988	38/18722	0.0138070705591761	0.0572677737131156	CLU/CD36/PICALM/RAB11A/ROCK1/RAB5A	6
GO:0098926	postsynaptic signal transduction	6/988	38/18722	0.0138070705591761	0.0572677737131156	AGRN/PLCB1/GNAI2/GNAQ/GNB1/STAT3	6
GO:2000279	negative regulation of DNA biosynthetic process	6/988	38/18722	0.0138070705591761	0.0572677737131156	ACVRL1/DACH1/BMPR2/DUSP1/GJA1/XRN1	6
GO:0008038	neuron recognition	7/988	49/18722	0.0138102443762239	0.0572677737131156	ROBO4/PCDH12/NRP1/APP/PALLD/NPTN/RTN4	7
GO:0038084	vascular endothelial growth factor signaling pathway	7/988	49/18722	0.0138102443762239	0.0572677737131156	KDR/VEGFC/ADGRA2/TSPAN12/NRP1/PIK3CA/MYO1C	7
GO:0046580	negative regulation of Ras protein signal transduction	7/988	49/18722	0.0138102443762239	0.0572677737131156	HEG1/RASIP1/RASA4/DLC1/ITGB1/TNFAIP1/PPP2CB	7
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	7/988	49/18722	0.0138102443762239	0.0572677737131156	THBS1/SKIL/PEA15/CFLAR/PTEN/FEM1B/SP100	7
GO:0002709	regulation of T cell mediated immunity	10/988	85/18722	0.0138728926582339	0.0574378844898973	FCGR2B/CEACAM1/IL1R1/HLA-E/HLA-A/AHR/HLA-B/B2M/CD81/TNFRSF1B	10
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	10/988	85/18722	0.0138728926582339	0.0574378844898973	IGF1/CAV1/SH2B3/SOCS3/IL6ST/FYN/PARP14/PARP9/HES1/ARL2BP	10
GO:1901991	negative regulation of mitotic cell cycle phase transition	17/988	179/18722	0.0138930214885925	0.0574764253484449	RGCC/ZFP36L1/RB1/DUSP1/PML/TAOK1/KLF4/PTEN/CTDSP2/PKD2/APC/CCND1/ZFP36L2/CTDSP1/WAC/FOXN3/PLK2	17
GO:1904029	regulation of cyclin-dependent protein kinase activity	11/988	98/18722	0.0141555082602282	0.0585167781154337	HHEX/RGCC/PDGFB/CCNY/PTEN/NR2F2/PKD2/APC/CCND1/CCNI/CCNT1	11
GO:0001818	negative regulation of cytokine production	29/988	357/18722	0.0142977782153351	0.0590589408086005	CD34/FCGR2B/BST2/IGF1/LRRC32/CEACAM1/FN1/SYT11/SRGN/KLF2/THBS1/ANGPT1/HDAC7/TMSB4X/RGCC/GIT1/CARD16/DICER1/PML/TGFB1/CD200/CARD8/TRIB2/KLF4/ZFP36/CYLD/NPTN/REL/TIA1	29
GO:0060997	dendritic spine morphogenesis	8/988	61/18722	0.0144061919594682	0.0594399816564171	PDLIM5/PTEN/ACTR2/ABI2/ADAM10/DIP2A/WASL/CDC42	8
GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	5/988	28/18722	0.0144571642131195	0.0594399816564171	EDN1/F2R/PLPP1/PRKD3/DGKH	5
GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	5/988	28/18722	0.0144571642131195	0.0594399816564171	CAV1/SH2B3/SOCS3/PARP14/LEPROT	5
GO:0060325	face morphogenesis	5/988	28/18722	0.0144571642131195	0.0594399816564171	CLDN5/RRAS/SKI/NIPBL/ANKRD11	5
GO:0090344	negative regulation of cell aging	5/988	28/18722	0.0144571642131195	0.0594399816564171	CDK6/MAP3K3/AKT3/PTEN/PLK2	5
GO:1903672	positive regulation of sprouting angiogenesis	5/988	28/18722	0.0144571642131195	0.0594399816564171	ITGA5/TJP1/SMAD1/JAK1/KLF4	5
GO:0019932	second-messenger-mediated signaling	26/988	312/18722	0.0146170858564123	0.0600510132012854	APLNR/EDN1/KDR/IGF1/SELP/NDNF/NPR1/LMCD1/ADGRG6/PDE4D/ITPR1/CLIC2/AHR/THBS1/RCAN1/DDAH2/CALM1/ITPR2/NFAT5/CD36/RAPGEF2/PPP3R1/ATP2B4/PPP3CA/PRKAA1/ZMPSTE24	26
GO:0030307	positive regulation of cell growth	16/988	166/18722	0.0146592006327046	0.0601774913144722	EDN1/IGF1/FN1/BMPR2/MACF1/RPS6KA3/NRP1/ITSN2/GDI1/RHOA/SDCBP/ADAM10/RUFY3/RAB11A/CDC42/EIF4G2	16
GO:0055007	cardiac muscle cell differentiation	13/988	125/18722	0.0147900170877931	0.0606676222164919	EDN1/IGF1/SORBS2/EFNB2/MEF2C/ITGB1/MEF2A/PDLIM5/TGFB1/TBX3/PLEC/SMAD4/ZMPSTE24	13
GO:0050867	positive regulation of cell activation	33/988	420/18722	0.0148926844854911	0.0610416203602844	IGF1/IL33/SELP/HLX/MEF2C/CAV1/HLA-E/HLA-A/THBS1/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/TGFB1/FYN/PIK3CA/LAMP1/TNFRSF14/RHOA/GATA2/ZMIZ1/CD320/CD46/HES1/KMT5B/RIF1/HSPH1/BCL10	33
GO:0006140	regulation of nucleotide metabolic process	10/988	86/18722	0.0149804773614177	0.061259658001425	IGF1/ZBTB20/TMSB4X/GIT1/PDK4/APP/HIF1A/OGT/STAT3/PRKAA1	10
GO:0034103	regulation of tissue remodeling	10/988	86/18722	0.0149804773614177	0.061259658001425	LEPR/S1PR1/CEACAM1/PDK4/MDK/TGFB1/PPP3CA/LTBP3/ROCK2/ROCK1	10
GO:0048864	stem cell development	10/988	86/18722	0.0149804773614177	0.061259658001425	EDN1/FN1/JAG1/NRP1/EFNB1/HIF1A/PHACTR4/SEMA3F/HES1/MAPK1	10
GO:0034612	response to tumor necrosis factor	22/988	253/18722	0.0150581286821459	0.0615298304304299	EDN1/FABP4/PLVAP/CRHBP/HYAL2/KLF2/THBS1/TMSB4X/ZFP36L1/ACTN4/CARD16/LIMS1/CARD8/TNFRSF14/ZFP36/CYLD/ADAM10/HIPK1/TNFRSF1B/ZFP36L2/HSPA1A/MAPK1	22
GO:0035601	protein deacylation	12/988	112/18722	0.0150972672894048	0.0615949952698296	APLNR/NNMT/FRY/HDAC7/ELK4/FLNA/SKI/TBL1XR1/PRKAA1/NIPBL/DYRK1A/BAZ2A	12
GO:0048640	negative regulation of developmental growth	12/988	112/18722	0.0150972672894048	0.0615949952698296	TGFBR2/NRP1/ADRB1/GJA1/PTEN/PLAC8/SEMA3F/RTN4/WWC2/SPAG9/WWC3/SAV1	12
GO:0033209	tumor necrosis factor-mediated signaling pathway	11/988	99/18722	0.0151913918450974	0.0619314454958999	PLVAP/TMSB4X/ACTN4/CARD16/LIMS1/CARD8/TNFRSF14/CYLD/HIPK1/TNFRSF1B/HSPA1A	11
GO:2001234	negative regulation of apoptotic signaling pathway	20/988	224/18722	0.0152732195938888	0.0622172871800132	IGF1/THBS1/CLU/PCGF2/NRP1/PEA15/RB1/GNAI2/CFLAR/FYN/ZMYND11/ITGA6/HIF1A/TMBIM6/RB1CC1/CTTN/CTNNA1/CD44/PHIP/HSPA1A	20
GO:0007632	visual behavior	7/988	50/18722	0.0153486083840267	0.0623808781453327	TANC1/ITGB1/APP/HIF1A/CREB1/NPTN/PIAS1	7
GO:0019083	viral transcription	7/988	50/18722	0.0153486083840267	0.0623808781453327	IFITM3/MDFIC/ZFP36/RSF1/TRIM13/JUN/CCNT1	7
GO:0038093	Fc receptor signaling pathway	7/988	50/18722	0.0153486083840267	0.0623808781453327	FCGR2B/PRKCE/YES1/FYN/PTK2/SOS1/RAP1A	7
GO:0001914	regulation of T cell mediated cytotoxicity	6/988	39/18722	0.0156089914681461	0.0633422174780689	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/B2M	6
GO:0046621	negative regulation of organ growth	6/988	39/18722	0.0156089914681461	0.0633422174780689	TGFBR2/GJA1/PTEN/WWC2/WWC3/SAV1	6
GO:0050866	negative regulation of cell activation	19/988	210/18722	0.0156290209365417	0.06337508337016	FCGR2B/ADGRF5/LRRC32/HLX/CEACAM1/FOXF1/THBD/SYT11/SH2B3/PDGFB/MDK/PKN1/CD200/PRKAR1A/TNFRSF14/RC3H1/CD9/CBLB/ID2	19
GO:0002253	activation of immune response	30/988	375/18722	0.0156443308654217	0.063388776168665	A2M/FCGR2B/CFI/CEACAM1/MEF2C/PDE4D/FOXP1/PRKCE/HLA-A/IFI16/RGCC/CLU/CD81/YES1/PRKCH/FYN/PIK3CA/PDE4B/CD59/CMTM3/PLSCR1/RC3H1/PAK2/CBLB/WNK1/CD46/PTK2/MAPK1/BCL10/RAP1A	30
GO:2001235	positive regulation of apoptotic signaling pathway	13/988	126/18722	0.0157230005360619	0.0636589777801531	TNFSF10/HYAL2/CAV1/THBS1/SKIL/SERINC3/PEA15/PML/PTEN/CYLD/CTNNA1/PAK2/BCL10	13
GO:0002260	lymphocyte homeostasis	8/988	62/18722	0.0157994438717689	0.063681602127739	MEF2C/SKIL/PKN1/HIF1A/RC3H1/SOS2/SOS1/BCL10	8
GO:0010759	positive regulation of macrophage chemotaxis	4/988	19/18722	0.0158244945046339	0.063681602127739	THBS1/MDK/PTK2/MAPK1	4
GO:0043031	negative regulation of macrophage activation	4/988	19/18722	0.0158244945046339	0.063681602127739	FCGR2B/ADGRF5/SYT11/CD200	4
GO:0044320	cellular response to leptin stimulus	4/988	19/18722	0.0158244945046339	0.063681602127739	LEPR/UGCG/PTEN/STAT3	4
GO:0045019	negative regulation of nitric oxide biosynthetic process	4/988	19/18722	0.0158244945046339	0.063681602127739	CD34/CAV1/ATP2B4/ROCK2	4
GO:0046794	transport of virus	4/988	19/18722	0.0158244945046339	0.063681602127739	BST2/CAV1/CAV2/KPNA3	4
GO:0060039	pericardium development	4/988	19/18722	0.0158244945046339	0.063681602127739	HEG1/NOTCH1/SMAD2/SOS1	4
GO:1904406	negative regulation of nitric oxide metabolic process	4/988	19/18722	0.0158244945046339	0.063681602127739	CD34/CAV1/ATP2B4/ROCK2	4
GO:0016485	protein processing	20/988	225/18722	0.0159628331004029	0.0641896816270552	CPE/ECE1/CLEC3B/RPS6KA2/PCSK5/SRGN/THBS1/IFI16/CARD16/XIAP/SPCS3/CPD/MYH9/CARD8/CAPN2/OGT/ADAM10/FAM111A/GSN/ZMPSTE24	20
GO:0030177	positive regulation of Wnt signaling pathway	14/988	140/18722	0.0160939362392433	0.06466791929112	RSPO3/ADGRA2/HHEX/CAV1/MACF1/DIXDC1/SULF2/SMURF2/XIAP/TGFB1/SKI/TBL1XR1/WNK1/CSNK1G3	14
GO:0060401	cytosolic calcium ion transport	17/988	182/18722	0.0161464592705842	0.064805602258739	APLNR/RAMP3/F2R/CAV1/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/PML/FYN/ERO1A/ITPR2/TMBIM6/PKD2/ATP2B4	17
GO:0150104	transport across blood-brain barrier	10/988	87/18722	0.0161526011653935	0.064805602258739	LEPR/FABP5/SLC38A2/SLC12A2/CD36/SLC44A1/SLC2A1/ATP2B4/SLC2A3/SLC16A2	10
GO:0002706	regulation of lymphocyte mediated immunity	16/988	168/18722	0.0162674572798885	0.0651679736581957	FCGR2B/CEACAM1/IL1R1/HLA-E/HLA-A/AHR/HLA-B/B2M/CD81/TGFB1/LAMP1/TNFRSF1B/CRK/CD46/KMT5B/RIF1	16
GO:0099173	postsynapse organization	16/988	168/18722	0.0162674572798885	0.0651679736581957	FCGR2B/TANC1/SRGN/NRP1/PDLIM5/FYN/PTEN/ACTR2/ABI2/NDRG1/ADAM10/SEMA3F/CTTN/DIP2A/WASL/CDC42	16
GO:0046474	glycerophospholipid biosynthetic process	19/988	211/18722	0.0163576864269023	0.0654307457076091	FABP5/DGKH/PIK3R3/PDGFB/SOCS3/PIK3CA/PIK3C2B/ACSL3/PTEN/CAPN2/SLC44A2/MTMR6/SLC44A1/PIK3C2A/PLSCR1/SOCS4/SMG1/FAR1/ETNK1	19
GO:0050807	regulation of synapse organization	19/988	211/18722	0.0163576864269023	0.0654307457076091	SPARC/FCGR2B/ADGRL2/ARHGEF15/MEF2C/AGRN/SRGN/TUBA1A/PDLIM5/APP/FYN/PTEN/ACTR2/RHOA/ABI2/ADAM10/SEMA3F/CDC42/NEDD4	19
GO:0050804	modulation of chemical synaptic transmission	34/988	439/18722	0.0165394578091702	0.0661080510777368	EDN1/P2RY1/PLCB4/LAMA2/MEF2C/SYT11/PLCB1/SRGN/PRKCE/ITGB1/KIF5B/GIT1/APP/GNAI2/SLC12A2/CALM1/STX3/FYN/PTEN/RNF19A/CREB1/STAT3/SLC30A1/NPTN/RAPGEF2/PPP3R1/PPP3CA/DLGAP4/PTPRA/RAB11A/MAPK1/PLK2/RAB5A/RAP1A	34
GO:0042594	response to starvation	18/988	197/18722	0.0166953703656642	0.0664663028013081	NUAK1/BMPR2/FOXO1/SLC38A2/IFI16/PDK4/ZFP36/RALB/EIF2AK2/ACAT1/SLC2A1/PRKAA1/XPR1/KLF10/SH3GLB1/TNRC6A/MAPK1/JUN	18
GO:0051224	negative regulation of protein transport	13/988	127/18722	0.0167001267097179	0.0664663028013081	F2R/ANGPT1/PPM1F/PKIG/MDFIC/CD200/GDI1/CD36/MAP4K4/PPP3CA/SP100/PIM3/MIDN	13
GO:0003209	cardiac atrium morphogenesis	5/988	29/18722	0.0167291880356455	0.0664663028013081	HEG1/ENG/BMPR2/NOTCH1/SOS1	5
GO:0006656	phosphatidylcholine biosynthetic process	5/988	29/18722	0.0167291880356455	0.0664663028013081	FABP5/ACSL3/CAPN2/SLC44A2/SLC44A1	5
GO:0019082	viral protein processing	5/988	29/18722	0.0167291880356455	0.0664663028013081	ST6GAL1/CANX/SPCS3/MGAT4A/PARP9	5
GO:0060969	negative regulation of gene silencing	5/988	29/18722	0.0167291880356455	0.0664663028013081	TGFB1/STAT3/ADAR/PPP3CA/ZMPSTE24	5
GO:0095500	acetylcholine receptor signaling pathway	5/988	29/18722	0.0167291880356455	0.0664663028013081	AGRN/PLCB1/GNAI2/GNAQ/GNB1	5
GO:2000406	positive regulation of T cell migration	5/988	29/18722	0.0167291880356455	0.0664663028013081	APP/TNFRSF14/RHOA/ADAM10/WNK1	5
GO:0051251	positive regulation of lymphocyte activation	29/988	362/18722	0.0169710028225908	0.0672599051944592	IGF1/HLX/MEF2C/CAV1/HLA-E/HLA-A/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/TGFB1/FYN/PIK3CA/LAMP1/TNFRSF14/RHOA/ZMIZ1/CD320/CD46/HES1/KMT5B/RIF1/HSPH1/BCL10	29
GO:0032873	negative regulation of stress-activated MAPK cascade	7/988	51/18722	0.0170049044947588	0.0672599051944592	MECOM/FOXO1/DUSP1/AIDA/ZMYND11/CYLD/HIPK3	7
GO:0045104	intermediate filament cytoskeleton organization	7/988	51/18722	0.0170049044947588	0.0672599051944592	VIM/MACF1/DST/ATXN3/CSNK1A1/PLEC/ATF2	7
GO:0060043	regulation of cardiac muscle cell proliferation	7/988	51/18722	0.0170049044947588	0.0672599051944592	MEF2C/NOTCH1/TGFBR2/GJA1/PTEN/MAPK1/SAV1	7
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	7/988	51/18722	0.0170049044947588	0.0672599051944592	MECOM/FOXO1/DUSP1/AIDA/ZMYND11/CYLD/HIPK3	7
GO:0071622	regulation of granulocyte chemotaxis	7/988	51/18722	0.0170049044947588	0.0672599051944592	EDN1/THBS1/MDK/JAM3/MOSPD2/PTK2/MAPK1	7
GO:0009749	response to glucose	19/988	212/18722	0.0171126092823874	0.0676355509732455	ZBTB20/ANGPT2/PRKCE/TXNIP/THBS1/TGFBR2/KIF5B/LGALS1/GJA1/PIK3CA/PTEN/RHOA/HIF1A/MAP4K4/EGR1/PPP3CA/PIM3/PRKAA1/SMAD2	19
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	12/988	114/18722	0.0171697406791848	0.0677046242766488	CDH5/ACVRL1/ENG/BMPR2/THBS1/NOTCH1/HIPK2/TGFB1/SDCBP/SMAD2/HES1/SMAD4	12
GO:0002696	positive regulation of leukocyte activation	32/988	409/18722	0.0172227363834262	0.0677046242766488	IGF1/IL33/HLX/MEF2C/CAV1/HLA-E/HLA-A/THBS1/TGFBR2/IGF2/B2M/CD81/LGALS1/MDK/YES1/EFNB1/IL6ST/TGFB1/FYN/PIK3CA/LAMP1/TNFRSF14/RHOA/GATA2/ZMIZ1/CD320/CD46/HES1/KMT5B/RIF1/HSPH1/BCL10	32
GO:0001756	somitogenesis	8/988	63/18722	0.0172875341145707	0.0677046242766488	MEOX2/LRP6/TCF15/FOXF1/NOTCH1/PLXNA2/MIB1/SMAD4	8
GO:0016239	positive regulation of macroautophagy	8/988	63/18722	0.0172875341145707	0.0677046242766488	KDR/SPTLC2/HIF1A/RALB/TRIM13/WAC/SH3GLB1/PAFAH1B2	8
GO:0030239	myofibril assembly	8/988	63/18722	0.0172875341145707	0.0677046242766488	EDN1/ITGB1/MEF2A/CFLAR/PRKAR1A/TMOD3/PLEC/SMAD4	8
GO:1904589	regulation of protein import	8/988	63/18722	0.0172875341145707	0.0677046242766488	HYAL2/ANGPT1/PKIG/MDFIC/TGFB1/FLNA/CD36/MAPK1	8
GO:0007260	tyrosine phosphorylation of STAT protein	10/988	88/18722	0.0173913568364781	0.0677046242766488	IGF1/CAV1/SH2B3/SOCS3/IL6ST/FYN/PARP14/PARP9/HES1/ARL2BP	10
GO:0048024	regulation of mRNA splicing, via spliceosome	11/988	101/18722	0.0174327072518728	0.0677046242766488	NOVA2/DDX17/MBNL1/QKI/CELF1/SON/MBNL2/RBM5/DYRK1A/HNRNPK/TIA1	11
GO:0031111	negative regulation of microtubule polymerization or depolymerization	6/988	40/18722	0.0175672616136661	0.0677046242766488	CDH5/TAOK1/APC/ARHGEF7/DYRK1A/CAMSAP2	6
GO:0045022	early endosome to late endosome transport	6/988	40/18722	0.0175672616136661	0.0677046242766488	MSN/FLNA/RDX/EMP2/MAPK1/RAB5A	6
GO:0072210	metanephric nephron development	6/988	40/18722	0.0175672616136661	0.0677046242766488	CD34/LAMB2/PDGFB/PKD2/EGR1/HES1	6
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	6/988	40/18722	0.0175672616136661	0.0677046242766488	SELP/ETS1/MDK/KLF4/NFAT5/RHOA	6
GO:2000142	regulation of DNA-templated transcription, initiation	6/988	40/18722	0.0175672616136661	0.0677046242766488	THRA/SETX/CREB1/MED13/ATF7IP/JUN	6
GO:2000781	positive regulation of double-strand break repair	6/988	40/18722	0.0175672616136661	0.0677046242766488	SLF2/ACTR2/PARP9/DTX3L/KMT5B/RIF1	6
GO:0001765	membrane raft assembly	3/988	11/18722	0.0175761816410954	0.0677046242766488	CAV1/CAV2/EMP2	3
GO:0001967	suckling behavior	3/988	11/18722	0.0175761816410954	0.0677046242766488	DACH1/APP/GLS	3
GO:0003157	endocardium development	3/988	11/18722	0.0175761816410954	0.0677046242766488	SOX18/NOTCH1/SMAD4	3
GO:0032836	glomerular basement membrane development	3/988	11/18722	0.0175761816410954	0.0677046242766488	NID1/LAMB2/SULF2	3
GO:0033210	leptin-mediated signaling pathway	3/988	11/18722	0.0175761816410954	0.0677046242766488	LEPR/UGCG/STAT3	3
GO:0033483	gas homeostasis	3/988	11/18722	0.0175761816410954	0.0677046242766488	CAV1/EGLN1/HIF1A	3
GO:0033625	positive regulation of integrin activation	3/988	11/18722	0.0175761816410954	0.0677046242766488	RASIP1/PIEZO1/FERMT2	3
GO:0033632	regulation of cell-cell adhesion mediated by integrin	3/988	11/18722	0.0175761816410954	0.0677046242766488	PODXL/PIEZO1/WNK1	3
GO:0034454	microtubule anchoring at centrosome	3/988	11/18722	0.0175761816410954	0.0677046242766488	CCDC68/PCM1/NIN	3
GO:0035457	cellular response to interferon-alpha	3/988	11/18722	0.0175761816410954	0.0677046242766488	IFIT3/IFNAR1/IFIT2	3
GO:0046929	negative regulation of neurotransmitter secretion	3/988	11/18722	0.0175761816410954	0.0677046242766488	SYT11/SLC30A1/RAP1A	3
GO:0048102	autophagic cell death	3/988	11/18722	0.0175761816410954	0.0677046242766488	TP53INP1/LAMP1/SH3GLB1	3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	3/988	11/18722	0.0175761816410954	0.0677046242766488	CLIC2/CALM1/PKD2	3
GO:0072017	distal tubule development	3/988	11/18722	0.0175761816410954	0.0677046242766488	JAG1/NOTCH1/PKD2	3
GO:0072110	glomerular mesangial cell proliferation	3/988	11/18722	0.0175761816410954	0.0677046242766488	PDGFB/CFLAR/EGR1	3
GO:0097494	regulation of vesicle size	3/988	11/18722	0.0175761816410954	0.0677046242766488	PICALM/RAB11A/RAB5A	3
GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	3/988	11/18722	0.0175761816410954	0.0677046242766488	GNAI2/PDE4B/ATP2B4	3
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	3/988	11/18722	0.0175761816410954	0.0677046242766488	CAV1/PDE4D/CALM1	3
GO:1902065	response to L-glutamate	3/988	11/18722	0.0175761816410954	0.0677046242766488	FYN/TMBIM6/CREB1	3
GO:2000392	regulation of lamellipodium morphogenesis	3/988	11/18722	0.0175761816410954	0.0677046242766488	ENPP2/CD44/ARHGEF7	3
GO:2000480	negative regulation of cAMP-dependent protein kinase activity	3/988	11/18722	0.0175761816410954	0.0677046242766488	PKIG/PRKAR1A/PRKAR2A	3
GO:1903320	regulation of protein modification by small protein conjugation or removal	21/988	242/18722	0.0176182087761604	0.0678173369702639	NXN/CAV1/FKBP1A/EPAS1/PRKCE/ANGPT1/SASH1/XIAP/FYN/PTEN/ISG15/HIF1A/OGT/ZMIZ1/EGR1/CBLB/DTX3L/TRIP12/HSPA1A/PIAS1/BCL10	21
GO:2001257	regulation of cation channel activity	17/988	184/18722	0.017799595188711	0.0684659302262365	CRHBP/MEF2C/CAV1/PDE4D/CLIC2/FKBP1A/ITGB1/TMSB4X/KIF5B/STOM/APP/CALM1/STIM2/PDE4B/AHNAK/PKD2/CRBN	17
GO:1903131	mononuclear cell differentiation	33/988	426/18722	0.0179598406897283	0.0690323254296938	FCGR2B/LEPR/HLX/ITM2A/HHEX/FOXP1/HLA-B/IFI16/TGFBR2/ITGB1/MFNG/B2M/ZFP36L1/LGALS1/CDK6/MDK/MYH9/LYL1/RHOA/STAT3/KLF6/ZMIZ1/EGR1/RC3H1/HECTD1/IRF2BP2/ZFP36L2/CD46/ATF2/SOS2/SOS1/ID2/JUN	33
GO:0097553	calcium ion transmembrane import into cytosol	14/988	142/18722	0.0180110281363758	0.0691790176864993	APLNR/RAMP3/F2R/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/FYN/ERO1A/ITPR2/PKD2/ATP2B4	14
GO:0034968	histone lysine methylation	12/988	115/18722	0.0182828588991819	0.0701723601679581	NNMT/MECOM/BCOR/KMT2E/ATRX/KMT2A/OGT/ASH1L/WDR82/KMT5B/RIF1/SMAD4	12
GO:0051222	positive regulation of protein transport	25/988	303/18722	0.0183419038591317	0.0703481540070092	IGF1/VEGFC/ABLIM3/NNAT/HYAL2/PRKCE/CD81/KIF5B/STOM/TGFB1/GJA1/FYN/ACSL3/FLNA/HIF1A/PCM1/MYO1C/RUFY3/LEPROT/PRKAA1/SH3GLB1/CDC42/MAPK1/OAZ2/CTDSPL2	25
GO:0001841	neural tube formation	11/988	102/18722	0.0186415773410579	0.071445929895887	DLC1/TGFB1/LUZP1/MIB1/HIF1A/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	11
GO:0010657	muscle cell apoptotic process	10/988	89/18722	0.018698813990016	0.0716136264707749	EDN1/IGF1/LRP6/RPS6KA2/MDK/GNB1/CFLAR/RGL2/PTEN/CAPN2	10
GO:0031103	axon regeneration	7/988	52/18722	0.0187834128031175	0.0716291426576369	SCARF1/LAMB2/JAM3/KLF4/PTEN/FLNA/CTNNA1	7
GO:0045103	intermediate filament-based process	7/988	52/18722	0.0187834128031175	0.0716291426576369	VIM/MACF1/DST/ATXN3/CSNK1A1/PLEC/ATF2	7
GO:0048260	positive regulation of receptor-mediated endocytosis	7/988	52/18722	0.0187834128031175	0.0716291426576369	BICD1/HIP1/ANGPT1/CLU/B2M/WASL/HNRNPK	7
GO:1903426	regulation of reactive oxygen species biosynthetic process	7/988	52/18722	0.0187834128031175	0.0716291426576369	CFLAR/FYN/CD36/RAB27A/RHOA/STAT3/CLCN3	7
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	13/988	129/18722	0.018791754114804	0.0716291426576369	SOX7/F2R/UACA/TNFSF10/HIP1/DLC1/PPM1F/PML/CFLAR/CARD8/RHOA/GSN/BCL10	13
GO:0006940	regulation of smooth muscle contraction	8/988	64/18722	0.0188737091951111	0.0716291426576369	EDN1/CALCRL/ITGA2/F2R/CAV1/DOCK4/RHOA/CTTN	8
GO:0045995	regulation of embryonic development	8/988	64/18722	0.0188737091951111	0.0716291426576369	LAMA4/LAMA2/PLCB1/PHLDB2/NIPBL/HES1/B4GALT5/TRIP12	8
GO:0055002	striated muscle cell development	8/988	64/18722	0.0188737091951111	0.0716291426576369	EDN1/ITGB1/MEF2A/CFLAR/PRKAR1A/TMOD3/PLEC/SMAD4	8
GO:0046890	regulation of lipid biosynthetic process	16/988	171/18722	0.0189311855068807	0.0716291426576369	ADGRF5/ZBTB20/CEACAM1/SCARB1/FABP5/IGFBP7/PDGFB/PDK4/LPGAT1/ACSL3/CAPN2/ELOVL5/CREB1/EGR1/STARD4/PRKAA1	16
GO:0048469	cell maturation	16/988	171/18722	0.0189311855068807	0.0716291426576369	SOX18/SCARF1/RPS6KA2/AGRN/EPAS1/KLF2/APP/ANKS1A/RB1/CDC25B/HIF1A/GATA2/FEM1B/PTBP3/HES1/B4GALT5	16
GO:0007097	nuclear migration	4/988	20/18722	0.0189725534110119	0.0716291426576369	SUN1/PCM1/DYNC1H1/CDC42	4
GO:0010523	negative regulation of calcium ion transport into cytosol	4/988	20/18722	0.0189725534110119	0.0716291426576369	CLIC2/CALM1/TMBIM6/PKD2	4
GO:0045844	positive regulation of striated muscle tissue development	4/988	20/18722	0.0189725534110119	0.0716291426576369	MEF2C/IGF2/CREB1/PRKAA1	4
GO:0048636	positive regulation of muscle organ development	4/988	20/18722	0.0189725534110119	0.0716291426576369	MEF2C/IGF2/CREB1/PRKAA1	4
GO:0060044	negative regulation of cardiac muscle cell proliferation	4/988	20/18722	0.0189725534110119	0.0716291426576369	TGFBR2/GJA1/PTEN/SAV1	4
GO:0061318	renal filtration cell differentiation	4/988	20/18722	0.0189725534110119	0.0716291426576369	PODXL/JAG1/LAMB2/IQGAP1	4
GO:0071731	response to nitric oxide	4/988	20/18722	0.0189725534110119	0.0716291426576369	FOXO1/CFLAR/EGLN1/CRK	4
GO:0072112	glomerular visceral epithelial cell differentiation	4/988	20/18722	0.0189725534110119	0.0716291426576369	PODXL/JAG1/LAMB2/IQGAP1	4
GO:0097150	neuronal stem cell population maintenance	4/988	20/18722	0.0189725534110119	0.0716291426576369	JAG1/NOTCH1/PCM1/HES1	4
GO:1990182	exosomal secretion	4/988	20/18722	0.0189725534110119	0.0716291426576369	RAB27A/SDCBP/PDCD6IP/RAB11A	4
GO:0046825	regulation of protein export from nucleus	5/988	30/18722	0.0192261413657929	0.0724835081157501	IFI27/SP100/PTPN14/XPO1/CTDSPL2	5
GO:0140058	neuron projection arborization	5/988	30/18722	0.0192261413657929	0.0724835081157501	FZD4/MACF1/NRP1/MYO9A/ROCK1	5
GO:0055074	calcium ion homeostasis	35/988	460/18722	0.0193311156145001	0.0728275788256912	APLNR/CDH5/EDN1/LRP6/KL/S1PR1/RAMP3/P2RY1/F2R/LPAR6/CAV1/CAV2/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/APP/CALM1/PML/GJA1/GNB1/FYN/STIM2/GTF2I/ERO1A/ITPR2/CD36/HSP90B1/TMBIM6/GATA2/SLC30A1/NPTN/PKD2/ATP2B4	35
GO:0098732	macromolecule deacylation	12/988	116/18722	0.0194491484385448	0.073220323533345	APLNR/NNMT/FRY/HDAC7/ELK4/FLNA/SKI/TBL1XR1/PRKAA1/NIPBL/DYRK1A/BAZ2A	12
GO:0051693	actin filament capping	6/988	41/18722	0.0196876452725404	0.074065702328424	SPTBN1/SPTAN1/TMOD3/RDX/ADD1/GSN	6
GO:0045055	regulated exocytosis	20/988	230/18722	0.0197846147394914	0.0743778297920584	FCGR2B/CRHBP/P2RY1/CEACAM1/FOXF1/SYT11/NOTCH1/GIT1/GNAI2/CALM1/STX3/MYH9/LAMP1/RAB27A/GATA2/SNAP23/S100A13/CTBP2/RAB5A/RAP1A	20
GO:0042770	signal transduction in response to DNA damage	16/988	172/18722	0.0198894321776406	0.0747189983929468	HIPK2/PML/TAOK1/ATRX/NDRG1/FEM1B/CD44/CLOCK/SP100/CCND1/WAC/ATF2/DYRK1A/FOXN3/PLK2/ZMPSTE24	16
GO:0043467	regulation of generation of precursor metabolites and energy	13/988	130/18722	0.0199087141719003	0.0747385792799535	IGF1/ZBTB20/COX7A1/IGF2/GIT1/APP/PIK3CA/RHOA/HIF1A/OGT/STAT3/IFNAR1/PRKAA1	13
GO:0017148	negative regulation of translation	21/988	245/18722	0.0199251205035787	0.0747473447139903	ZFP36L1/PABPC1/ZFP36/PURA/STAT3/EIF2AK2/TNRC6B/CELF1/CNOT6L/RC3H1/ENC1/ZFP36L2/CNOT8/ROCK2/DDX6/TNRC6A/ROCK1/CNOT2/XRN1/BTG2/TIA1	21
GO:0002366	leukocyte activation involved in immune response	23/988	275/18722	0.0199537977181612	0.0748020984325139	FCGR2B/HLX/CEACAM1/FOXF1/ITM2A/FOXP1/PRKCE/MFNG/CD81/LGALS1/MDK/TGFB1/LAMP1/RAB27A/DYSF/STAT3/GATA2/SNAP23/RC3H1/S100A13/CD46/KMT5B/RIF1	23
GO:0061097	regulation of protein tyrosine kinase activity	10/988	90/18722	0.0200770145535781	0.0752109318114293	HYAL2/CAV1/SH3BP5/NEDD9/PDGFB/APP/SHC1/SOCS4/PAK2/CBLB	10
GO:0010324	membrane invagination	14/988	144/18722	0.0200967957968144	0.0752319797552346	FCGR2B/ITGA2/SYT11/THBS1/ELMO1/MYH9/CD36/RHOA/GATA2/ABCA1/GSN/CLCN3/CDC42/DOCK1	14
GO:0006979	response to oxidative stress	34/988	446/18722	0.0203931860252537	0.0762877494127801	EDN1/MSRB3/HYAL2/FOXO1/EPAS1/ETS1/KLF2/TXNIP/RCAN1/RHOB/PCGF2/PXN/APP/DUSP1/PML/FYN/TP53INP1/KLF4/NCOA7/CAPN2/ERO1A/SETX/CD36/HIF1A/PKD2/PPP2CB/PRKAA1/CRK/ATF2/HSPA1A/MAPK1/JUN/PSIP1/NFE2L1	34
GO:0002720	positive regulation of cytokine production involved in immune response	8/988	65/18722	0.0205611334284702	0.0766999584073269	IL1R1/HLA-E/HLA-A/B2M/CD81/TNFRSF14/CD36/BCL10	8
GO:0045682	regulation of epidermis development	8/988	65/18722	0.0205611334284702	0.0766999584073269	CD109/NOTCH1/ZFP36L1/PRKCH/ZFP36/HES1/ROCK2/ROCK1	8
GO:0060389	pathway-restricted SMAD protein phosphorylation	8/988	65/18722	0.0205611334284702	0.0766999584073269	ACVRL1/SMAD6/ENG/BMPR2/TGFBR2/TGFB1/SDCBP/SMAD4	8
GO:0070613	regulation of protein processing	8/988	65/18722	0.0205611334284702	0.0766999584073269	CLEC3B/RPS6KA2/THBS1/CARD16/XIAP/MYH9/CARD8/GSN	8
GO:0007566	embryo implantation	7/988	53/18722	0.0206882610137564	0.0770659484607814	PCSK5/TGFBR2/IGFBP7/TIMP1/SMURF2/GJA1/EMP2	7
GO:0016925	protein sumoylation	7/988	53/18722	0.0206882610137564	0.0770659484607814	HDAC7/PML/RANBP2/ZMIZ1/EGR1/PIAS1/SENP6	7
GO:0051402	neuron apoptotic process	21/988	246/18722	0.0207440595757484	0.0772196527444818	NDNF/F2R/MEF2C/ITGA1/ANGPT1/NRP1/HIPK2/APP/RB1/XIAP/MDK/FYN/PIK3CA/MAP3K11/RHOA/HIF1A/ATF2/GBE1/CDC42/BTG2/JUN	21
GO:0017157	regulation of exocytosis	18/988	202/18722	0.0209832096938922	0.0780551890013695	FCGR2B/STXBP6/P2RY1/CEACAM1/FOXF1/SYT11/NOTCH1/GIT1/GNAI2/CALM1/LAMP1/RAB27A/SDCBP/GATA2/PDCD6IP/RALA/RAB5A/RAP1A	18
GO:1904950	negative regulation of establishment of protein localization	13/988	131/18722	0.0210747310355242	0.0783407776491984	F2R/ANGPT1/PPM1F/PKIG/MDFIC/CD200/GDI1/CD36/MAP4K4/PPP3CA/SP100/PIM3/MIDN	13
GO:0032963	collagen metabolic process	11/988	104/18722	0.0212442159215424	0.0789155769057576	VIM/ITGA2/F2R/ENG/ADAM15/ITGB1/RGCC/TGFB1/SERPINH1/HIF1A/RAP1A	11
GO:0008306	associative learning	9/988	78/18722	0.0213722568151553	0.0793357290021699	TANC1/ITGB1/APP/ACTR2/HIF1A/CREB1/NPTN/PIAS1/BTG2	9
GO:0072080	nephron tubule development	10/988	91/18722	0.0215279682741261	0.0798579381788811	DCHS1/WWTR1/MEF2C/JAG1/NOTCH1/PKD2/ACAT1/HES1/SMAD4/MTSS1	10
GO:0006874	cellular calcium ion homeostasis	34/988	448/18722	0.0216161173694745	0.0801289710165028	APLNR/CDH5/EDN1/LRP6/S1PR1/RAMP3/P2RY1/F2R/LPAR6/CAV1/CAV2/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/APP/CALM1/PML/GJA1/GNB1/FYN/STIM2/GTF2I/ERO1A/ITPR2/CD36/HSP90B1/TMBIM6/GATA2/SLC30A1/NPTN/PKD2/ATP2B4	34
GO:0045786	negative regulation of cell cycle	30/988	385/18722	0.0216326201179659	0.0801342245931904	RPS6KA2/HHEX/RHOB/RGCC/ZFP36L1/RB1/CDK6/DUSP1/PML/TGFB1/TAOK1/ATRX/PRKAR1A/KLF4/PTEN/NR2F2/CTDSP2/PKD2/FEM1B/APC/HECA/CLOCK/CCND1/ZFP36L2/CTDSP1/WAC/ATF2/FOXN3/BTG2/PLK2	30
GO:0071346	cellular response to interferon-gamma	12/988	118/18722	0.021946919045305	0.0806733261048327	VIM/EDN1/GBP4/FLNB/KIF5B/JAK1/PARP14/ACTR2/PARP9/MYO1C/SP100/CDC42	12
GO:0002063	chondrocyte development	5/988	31/18722	0.0219557262060935	0.0806733261048327	BMPR2/TGFBR2/SULF2/CHSY1/SERPINH1	5
GO:0045987	positive regulation of smooth muscle contraction	5/988	31/18722	0.0219557262060935	0.0806733261048327	EDN1/ITGA2/F2R/RHOA/CTTN	5
GO:0048566	embryonic digestive tract development	5/988	31/18722	0.0219557262060935	0.0806733261048327	HLX/FOXF1/PCSK5/NIPBL/ID2	5
GO:0051569	regulation of histone H3-K4 methylation	5/988	31/18722	0.0219557262060935	0.0806733261048327	NNMT/BCOR/KMT2E/KMT2A/SMAD4	5
GO:0060390	regulation of SMAD protein signal transduction	5/988	31/18722	0.0219557262060935	0.0806733261048327	SPTBN1/WWTR1/BMPR2/TGFB1/SMAD4	5
GO:0061099	negative regulation of protein tyrosine kinase activity	5/988	31/18722	0.0219557262060935	0.0806733261048327	HYAL2/CAV1/SH3BP5/SOCS4/CBLB	5
GO:0070723	response to cholesterol	5/988	31/18722	0.0219557262060935	0.0806733261048327	LRP6/TGFBR2/TGFB1/ABCA1/SMAD2	5
GO:0010591	regulation of lamellipodium assembly	6/988	42/18722	0.0219755841253187	0.0806733261048327	FSCN1/NCKAP1/PIK3CA/ACTR2/ABI2/CDC42	6
GO:0032467	positive regulation of cytokinesis	6/988	42/18722	0.0219755841253187	0.0806733261048327	PKP4/PRKCE/CDC25B/RHOA/PKN2/CDC42	6
GO:0035019	somatic stem cell population maintenance	6/988	42/18722	0.0219755841253187	0.0806733261048327	LDB2/SKI/GATA2/ZFP36L2/KLF10/HES1	6
GO:0090317	negative regulation of intracellular protein transport	6/988	42/18722	0.0219755841253187	0.0806733261048327	ANGPT1/PKIG/MDFIC/GDI1/CD36/SP100	6
GO:2001222	regulation of neuron migration	6/988	42/18722	0.0219755841253187	0.0806733261048327	COL3A1/MDK/FLNA/STAT3/RAPGEF2/NIPBL	6
GO:0050803	regulation of synapse structure or activity	19/988	218/18722	0.0222271643078715	0.0809214275929573	SPARC/FCGR2B/ADGRL2/ARHGEF15/MEF2C/AGRN/SRGN/TUBA1A/PDLIM5/APP/FYN/PTEN/ACTR2/RHOA/ABI2/ADAM10/SEMA3F/CDC42/NEDD4	19
GO:0050918	positive chemotaxis	8/988	66/18722	0.0223528792290209	0.0809214275929573	KDR/S1PR1/VEGFC/ITGA2/ANGPT2/ANGPT1/NRP1/PDGFB	8
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	20/988	233/18722	0.022396315985231	0.0809214275929573	RAMP2/EDN1/CALCRL/ADGRL4/ADGRL2/S1PR1/RAMP3/P2RY1/ADCY4/ADGRG6/PDE4D/GNAI2/ADRB1/GNAQ/GNB1/PDE4B/FLNA/ABCA1/RAPGEF2/ATP2B4	20
GO:0010878	cholesterol storage	4/988	21/18722	0.0224812884128176	0.0809214275929573	SCARB1/CD36/ABCA1/STARD4	4
GO:0030502	negative regulation of bone mineralization	4/988	21/18722	0.0224812884128176	0.0809214275929573	SRGN/BCOR/HIF1A/LTBP3	4
GO:0038083	peptidyl-tyrosine autophosphorylation	4/988	21/18722	0.0224812884128176	0.0809214275929573	KDR/CAV1/IQGAP1/DYRK1A	4
GO:0044766	multi-organism transport	4/988	21/18722	0.0224812884128176	0.0809214275929573	BST2/CAV1/CAV2/KPNA3	4
GO:0045056	transcytosis	4/988	21/18722	0.0224812884128176	0.0809214275929573	FCGRT/PICALM/RAB11A/RAB5A	4
GO:0045655	regulation of monocyte differentiation	4/988	21/18722	0.0224812884128176	0.0809214275929573	FOXP1/ZFP36L1/CDK6/JUN	4
GO:0046597	negative regulation of viral entry into host cell	4/988	21/18722	0.0224812884128176	0.0809214275929573	IFITM2/IFITM3/IFITM1/GSN	4
GO:0046641	positive regulation of alpha-beta T cell proliferation	4/988	21/18722	0.0224812884128176	0.0809214275929573	HLA-E/HLA-A/TGFBR2/CD81	4
GO:0072170	metanephric tubule development	4/988	21/18722	0.0224812884128176	0.0809214275929573	WWTR1/PKD2/ACAT1/HES1	4
GO:0072311	glomerular epithelial cell differentiation	4/988	21/18722	0.0224812884128176	0.0809214275929573	PODXL/JAG1/LAMB2/IQGAP1	4
GO:0097062	dendritic spine maintenance	4/988	21/18722	0.0224812884128176	0.0809214275929573	FCGR2B/TANC1/FYN/CTTN	4
GO:1901863	positive regulation of muscle tissue development	4/988	21/18722	0.0224812884128176	0.0809214275929573	MEF2C/IGF2/CREB1/PRKAA1	4
GO:1902579	multi-organism localization	4/988	21/18722	0.0224812884128176	0.0809214275929573	BST2/CAV1/CAV2/KPNA3	4
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	4/988	21/18722	0.0224812884128176	0.0809214275929573	CFLAR/FYN/RHOA/STAT3	4
GO:0002664	regulation of T cell tolerance induction	3/988	12/18722	0.022530645973265	0.0809214275929573	HLA-B/TGFBR2/CBLB	3
GO:0034392	negative regulation of smooth muscle cell apoptotic process	3/988	12/18722	0.022530645973265	0.0809214275929573	EDN1/IGF1/LRP6	3
GO:0043301	negative regulation of leukocyte degranulation	3/988	12/18722	0.022530645973265	0.0809214275929573	FCGR2B/CEACAM1/FOXF1	3
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	3/988	12/18722	0.022530645973265	0.0809214275929573	IGFBP4/IGF1/PHIP	3
GO:0045916	negative regulation of complement activation	3/988	12/18722	0.022530645973265	0.0809214275929573	A2M/CD59/CD46	3
GO:0060009	Sertoli cell development	3/988	12/18722	0.022530645973265	0.0809214275929573	ATRX/FLNA/FNDC3A	3
GO:0060019	radial glial cell differentiation	3/988	12/18722	0.022530645973265	0.0809214275929573	RHOA/STAT3/HES1	3
GO:0061307	cardiac neural crest cell differentiation involved in heart development	3/988	12/18722	0.022530645973265	0.0809214275929573	JAG1/HES1/MAPK1	3
GO:0061308	cardiac neural crest cell development involved in heart development	3/988	12/18722	0.022530645973265	0.0809214275929573	JAG1/HES1/MAPK1	3
GO:0071107	response to parathyroid hormone	3/988	12/18722	0.022530645973265	0.0809214275929573	ITGA2/MEF2C/GJA1	3
GO:0090331	negative regulation of platelet aggregation	3/988	12/18722	0.022530645973265	0.0809214275929573	CEACAM1/SH2B3/CD9	3
GO:0090557	establishment of endothelial intestinal barrier	3/988	12/18722	0.022530645973265	0.0809214275929573	TJP1/RAPGEF2/F11R	3
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	3/988	12/18722	0.022530645973265	0.0809214275929573	TMBIM6/HSPA1A/JUN	3
GO:1905205	positive regulation of connective tissue replacement	3/988	12/18722	0.022530645973265	0.0809214275929573	PPP3CA/ROCK2/ROCK1	3
GO:2000727	positive regulation of cardiac muscle cell differentiation	3/988	12/18722	0.022530645973265	0.0809214275929573	EFNB2/MEF2C/TGFB1	3
GO:0062207	regulation of pattern recognition receptor signaling pathway	11/988	105/18722	0.0226413115560217	0.0812639506659373	CAV1/SEC14L1/DDX60/TSPAN6/XIAP/CD36/RTN4/WDFY1/PJA2/PUM2/HSPA1A	11
GO:0010659	cardiac muscle cell apoptotic process	7/988	54/18722	0.02272340930594	0.0815035450595229	RPS6KA2/MDK/GNB1/CFLAR/RGL2/PTEN/CAPN2	7
GO:0071383	cellular response to steroid hormone stimulus	18/988	204/18722	0.0229168779285372	0.0821420077978336	EDN1/PLPP1/FOXO1/TFPI/FOXP1/ZFP36L1/DDX17/PKN1/CFLAR/RHOA/ZFP36/ZMIZ1/CLOCK/ZFP36L2/NR3C1/CNOT2/NEDD4/ARID1A	18
GO:1901184	regulation of ERBB signaling pathway	9/988	79/18722	0.0230319225609335	0.0824987003666073	CEACAM1/HIP1/ITGA1/RTN4/CCDC88A/SOCS4/CBLB/SOS1/PTPN12	9
GO:1902105	regulation of leukocyte differentiation	23/988	279/18722	0.0231719350471971	0.0829268960766128	FCGR2B/HLX/CEACAM1/FOXP1/HLA-B/TGFBR2/ZFP36L1/RB1/CDK6/MDK/TGFB1/RHOA/CREB1/GATA2/ZMIZ1/RC3H1/ZFP36L2/CD46/KLF10/SOS2/SOS1/ID2/JUN	23
GO:0009746	response to hexose	19/988	219/18722	0.0231826883798513	0.0829268960766128	ZBTB20/ANGPT2/PRKCE/TXNIP/THBS1/TGFBR2/KIF5B/LGALS1/GJA1/PIK3CA/PTEN/RHOA/HIF1A/MAP4K4/EGR1/PPP3CA/PIM3/PRKAA1/SMAD2	19
GO:0009855	determination of bilateral symmetry	13/988	133/18722	0.0235587498995886	0.0842153966800906	APLNR/SOX18/FOXF1/MEF2C/ENG/NOTCH1/TGFBR2/AIDA/MIB1/HIF1A/PKD2/TBX3/SMAD2	13
GO:0090263	positive regulation of canonical Wnt signaling pathway	11/988	106/18722	0.0241044341316996	0.0861081063265557	RSPO3/ADGRA2/HHEX/CAV1/SULF2/SMURF2/XIAP/TGFB1/TBL1XR1/WNK1/CSNK1G3	11
GO:0048705	skeletal system morphogenesis	19/988	220/18722	0.0241692598294999	0.0862237127026886	MGP/TEK/TCF15/HYAL2/MEF2C/BMPR2/FGFR1/THRA/TGFBR2/PCGF2/CHSY1/SERPINH1/SKI/LTBP3/SMAD2/NIPBL/FOXN3/ANKRD11/ZMPSTE24	19
GO:0097529	myeloid leukocyte migration	19/988	220/18722	0.0241692598294999	0.0862237127026886	PECAM1/EDN1/VEGFC/MTUS1/ITGA1/IL1R1/PLCB1/THBS1/CD81/PDGFB/MDK/DUSP1/JAM3/CD200/PDE4B/MOSPD2/CD9/PTK2/MAPK1	19
GO:0035914	skeletal muscle cell differentiation	8/988	67/18722	0.0242519177705864	0.0862678634902767	MEF2C/NOTCH1/DDX17/RB1/EGR1/FOXN2/NR1D2/BTG2	8
GO:0050435	amyloid-beta metabolic process	8/988	67/18722	0.0242519177705864	0.0862678634902767	IGF1/CLU/ADAM10/RTN4/PICALM/ROCK2/DYRK1A/ROCK1	8
GO:0061180	mammary gland epithelium development	8/988	67/18722	0.0242519177705864	0.0862678634902767	FOXF1/PML/HIF1A/RTN4/TBX3/CCND1/MAPK1/ID2	8
GO:1903317	regulation of protein maturation	8/988	67/18722	0.0242519177705864	0.0862678634902767	CLEC3B/RPS6KA2/THBS1/CARD16/XIAP/MYH9/CARD8/GSN	8
GO:0006417	regulation of translation	35/988	468/18722	0.0242628366066403	0.0862678634902767	VIM/ITGA2/THBS1/RPS6KA3/ZFP36L1/APP/EIF4G3/PABPC1/RHOA/QKI/ZFP36/PURA/STAT3/EIF2AK2/CSDE1/TNRC6B/CELF1/CNOT6L/RC3H1/ENC1/ZFP36L2/CNOT8/SECISBP2L/PUM2/ROCK2/DDX6/TNRC6A/ROCK1/EIF4G2/CNOT2/MAPK1/XRN1/CNBP/BTG2/TIA1	35
GO:0002861	regulation of inflammatory response to antigenic stimulus	6/988	43/18722	0.0244361743740191	0.0864789861923981	FCGR2B/HLA-E/CD81/YES1/FYN/PLK2	6
GO:0006509	membrane protein ectodomain proteolysis	6/988	43/18722	0.0244361743740191	0.0864789861923981	TIMP1/ERAP1/MYH9/ADAM10/TNFRSF1B/ROCK1	6
GO:0010171	body morphogenesis	6/988	43/18722	0.0244361743740191	0.0864789861923981	CLDN5/PHLDB2/RRAS/SKI/NIPBL/ANKRD11	6
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	6/988	43/18722	0.0244361743740191	0.0864789861923981	CDH5/SELP/PCDH12/DCHS1/FXYD5/KIFAP3	6
GO:0031952	regulation of protein autophosphorylation	6/988	43/18722	0.0244361743740191	0.0864789861923981	VEGFC/ENG/CAV1/PDGFB/CALM1/IQGAP1	6
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	6/988	43/18722	0.0244361743740191	0.0864789861923981	IFI16/HIPK2/PML/HIPK1/CD44/HNRNPK	6
GO:0098927	vesicle-mediated transport between endosomal compartments	6/988	43/18722	0.0244361743740191	0.0864789861923981	MSN/FLNA/RDX/EMP2/MAPK1/RAB5A	6
GO:0007589	body fluid secretion	10/988	93/18722	0.0246559867347671	0.0871407861178196	EDN1/NPR1/CAV1/PAM/PRKCE/OAS2/HIF1A/CREB1/CCND1/WNK1	10
GO:0060349	bone morphogenesis	10/988	93/18722	0.0246559867347671	0.0871407861178196	TEK/MEF2C/BMPR2/TGFBR2/CHSY1/SERPINH1/SKI/LTBP3/FOXN3/ZMPSTE24	10
GO:0035148	tube formation	14/988	148/18722	0.0248081450181925	0.0875088693504037	NFIB/PODXL/DLC1/NOTCH1/TGFB1/LUZP1/MIB1/HIF1A/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	14
GO:0009799	specification of symmetry	13/988	134/18722	0.0248791267294066	0.0875088693504037	APLNR/SOX18/FOXF1/MEF2C/ENG/NOTCH1/TGFBR2/AIDA/MIB1/HIF1A/PKD2/TBX3/SMAD2	13
GO:0031113	regulation of microtubule polymerization	7/988	55/18722	0.024892636128542	0.0875088693504037	CDH5/GIT1/ARHGEF7/DYRK1A/HSPA1A/CAMSAP2/NIN	7
GO:1902991	regulation of amyloid precursor protein catabolic process	7/988	55/18722	0.024892636128542	0.0875088693504037	IGF1/FKBP1A/CLU/RTN4/PICALM/ROCK2/ROCK1	7
GO:0007435	salivary gland morphogenesis	5/988	32/18722	0.0249248718612878	0.0875088693504037	NFIB/PLXND1/NRP1/TGFB1/CDC42	5
GO:0010644	cell communication by electrical coupling	5/988	32/18722	0.0249248718612878	0.0875088693504037	CAV1/PDE4D/CALM1/GJA1/GJA5	5
GO:0051642	centrosome localization	5/988	32/18722	0.0249248718612878	0.0875088693504037	KIF5B/PLXNA2/SUN1/RANBP2/NIN	5
GO:0060323	head morphogenesis	5/988	32/18722	0.0249248718612878	0.0875088693504037	CLDN5/RRAS/SKI/NIPBL/ANKRD11	5
GO:0061036	positive regulation of cartilage development	5/988	32/18722	0.0249248718612878	0.0875088693504037	ACVRL1/LOXL2/BMPR2/SMAD1/MDK	5
GO:1905476	negative regulation of protein localization to membrane	5/988	32/18722	0.0249248718612878	0.0875088693504037	PPP2R5A/TGFB1/GDI1/PICALM/HECTD1	5
GO:1901987	regulation of cell cycle phase transition	30/988	390/18722	0.0252370109773675	0.0885462366656382	PLCB1/RGCC/ZFP36L1/KMT2E/APP/RB1/DUSP1/PML/TAOK1/CDC25B/TMOD3/KLF4/PTEN/RDX/CTDSP2/PKD2/FEM1B/ATP2B4/APC/CLOCK/CCND1/ZFP36L2/CDC27/CTDSP1/WAC/ATF2/RAB11A/FOXN3/ID2/PLK2	30
GO:0006816	calcium ion transport	32/988	422/18722	0.0255213382665034	0.0894847187271725	APLNR/RAMP2/CALCRL/RAMP3/F2R/CAV1/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/PDGFB/GNAI2/SARAF/CALM1/PML/GJA1/FYN/SESTD1/STIM2/PDE4B/ERO1A/ITPR2/RHOA/TMBIM6/AHNAK/SLC30A1/PKD2/ATP2B4/PPP3CA/SEC61A1/ZMPSTE24	32
GO:0032526	response to retinoic acid	11/988	107/18722	0.0256351794280354	0.0897062405281451	HSD17B2/TIE1/FZD4/IGFBP7/YES1/DUSP1/GJA1/KLF4/SETX/CREB1/ABCA1	11
GO:0042303	molting cycle	11/988	107/18722	0.0256351794280354	0.0897062405281451	LDB2/SOX18/CD109/NOTCH1/FZD6/CLOCK/NIPBL/SOS1/SMAD4/SAV1/ZMPSTE24	11
GO:0042633	hair cycle	11/988	107/18722	0.0256351794280354	0.0897062405281451	LDB2/SOX18/CD109/NOTCH1/FZD6/CLOCK/NIPBL/SOS1/SMAD4/SAV1/ZMPSTE24	11
GO:0010976	positive regulation of neuron projection development	15/988	163/18722	0.025750691082564	0.089991888835908	NDNF/SCARF1/MDK/SCARB2/CFLAR/FYN/SETX/FLNA/ACTR2/ITGA6/NPTN/RAPGEF2/ENC1/IQGAP1/RAP1A	15
GO:0061025	membrane fusion	15/988	163/18722	0.025750691082564	0.089991888835908	TIE1/STXBP6/HYAL2/CAV2/SYT11/HACE1/KIF5B/STX3/TBC1D4/SAMD9/DYSF/SNAP23/YIPF4/CD9/MYOF	15
GO:0010951	negative regulation of endopeptidase activity	21/988	252/18722	0.0262172929403551	0.0913380608252527	A2M/BST2/CD109/PROS1/TFPI2/TFPI/THBS1/IFI16/RPS6KA3/TIMP1/CRIM1/CARD16/APP/XIAP/CARD8/KLF4/SERPINH1/PICALM/CD44/PAK2/ROCK1	21
GO:0045017	glycerolipid biosynthetic process	21/988	252/18722	0.0262172929403551	0.0913380608252527	SCARB1/FABP5/DGKH/PIK3R3/PDGFB/SOCS3/LPGAT1/PIK3CA/PIK3C2B/ACSL3/PTEN/CAPN2/SLC44A2/MTMR6/SLC44A1/PIK3C2A/PLSCR1/SOCS4/SMG1/FAR1/ETNK1	21
GO:0014020	primary neural tube formation	10/988	94/18722	0.0263368705261577	0.0913380608252527	DLC1/TGFB1/LUZP1/HIF1A/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	10
GO:0032091	negative regulation of protein binding	10/988	94/18722	0.0263368705261577	0.0913380608252527	CAV1/ADAM15/ID1/B2M/PDGFB/CARD16/TMBIM6/RALB/IFIT2/ROCK1	10
GO:0002089	lens morphogenesis in camera-type eye	4/988	22/18722	0.0263594215446371	0.0913380608252527	HIPK2/ABI2/SKI/HIPK1	4
GO:0002320	lymphoid progenitor cell differentiation	4/988	22/18722	0.0263594215446371	0.0913380608252527	NOTCH1/HES1/SOS2/SOS1	4
GO:0035809	regulation of urine volume	4/988	22/18722	0.0263594215446371	0.0913380608252527	EDN1/NPR1/HYAL2/GNAI2	4
GO:0036120	cellular response to platelet-derived growth factor stimulus	4/988	22/18722	0.0263594215446371	0.0913380608252527	YES1/FYN/RDX/CREB1	4
GO:0048169	regulation of long-term neuronal synaptic plasticity	4/988	22/18722	0.0263594215446371	0.0913380608252527	APP/NPTN/RAB11A/RAB5A	4
GO:0051220	cytoplasmic sequestering of protein	4/988	22/18722	0.0263594215446371	0.0913380608252527	TMSB4X/FLNA/PKD2/YWHAB	4
GO:0060965	negative regulation of gene silencing by miRNA	4/988	22/18722	0.0263594215446371	0.0913380608252527	TGFB1/STAT3/PPP3CA/ZMPSTE24	4
GO:2000725	regulation of cardiac muscle cell differentiation	4/988	22/18722	0.0263594215446371	0.0913380608252527	EFNB2/MEF2C/TGFB1/SMAD4	4
GO:2000773	negative regulation of cellular senescence	4/988	22/18722	0.0263594215446371	0.0913380608252527	CDK6/MAP3K3/AKT3/PLK2	4
GO:0001942	hair follicle development	9/988	81/18722	0.0266236291166057	0.0920134794192644	LDB2/SOX18/CD109/NOTCH1/FZD6/SOS1/SMAD4/SAV1/ZMPSTE24	9
GO:0051149	positive regulation of muscle cell differentiation	9/988	81/18722	0.0266236291166057	0.0920134794192644	EDN1/IGF1/EFNB2/MEF2C/ENG/PIEZO1/ATP11A/TGFB1/PIAS1	9
GO:0071260	cellular response to mechanical stimulus	9/988	81/18722	0.0266236291166057	0.0920134794192644	ITGA2/ENG/PIEZO1/SLC38A2/GJA1/SLC2A1/F11R/PLEC/BCL10	9
GO:1903533	regulation of protein targeting	9/988	81/18722	0.0266236291166057	0.0920134794192644	ABLIM3/STOM/FYN/GDI1/MYO1C/LEPROT/PRKAA1/NUCB1/SH3GLB1	9
GO:0046486	glycerolipid metabolic process	30/988	392/18722	0.0268032387552578	0.092573994972646	PLA1A/ENPP2/CAV1/SCARB1/PLCB1/FABP5/DGKH/SERINC3/PIK3R3/PDGFB/SERINC1/OSBPL10/SOCS3/CPT1A/LPGAT1/PIK3CA/PIK3C2B/ACSL3/PTEN/CAPN2/SEL1L/SLC44A2/MTMR6/SLC44A1/PIK3C2A/PLSCR1/SOCS4/SMG1/FAR1/ETNK1	30
GO:0007528	neuromuscular junction development	6/988	44/18722	0.027074146403041	0.0932066530738521	F2R/COL4A1/AGRN/LAMB2/APP/NEDD4	6
GO:0042269	regulation of natural killer cell mediated cytotoxicity	6/988	44/18722	0.027074146403041	0.0932066530738521	CEACAM1/HLA-E/HLA-A/HLA-B/LAMP1/CRK	6
GO:0050999	regulation of nitric-oxide synthase activity	6/988	44/18722	0.027074146403041	0.0932066530738521	CAV1/SCARB1/DDAH2/CALM1/HIF1A/ATP2B4	6
GO:0060324	face development	6/988	44/18722	0.027074146403041	0.0932066530738521	CLDN5/RRAS/SKI/NIPBL/MAPK1/ANKRD11	6
GO:0150076	neuroinflammatory response	6/988	44/18722	0.027074146403041	0.0932066530738521	IGF1/IL33/SYT11/ITGB1/CD200/TNFRSF1B	6
GO:0010658	striated muscle cell apoptotic process	7/988	56/18722	0.0271995249710694	0.093275582082841	RPS6KA2/MDK/GNB1/CFLAR/RGL2/PTEN/CAPN2	7
GO:0031122	cytoplasmic microtubule organization	7/988	56/18722	0.0271995249710694	0.093275582082841	DST/RHOA/PCM1/CCDC88A/RAB11A/DYNC1H1/CAMSAP2	7
GO:0046622	positive regulation of organ growth	7/988	56/18722	0.0271995249710694	0.093275582082841	EDN1/IGF1/HLX/MEF2C/NOTCH1/IGF2/MAPK1	7
GO:0051653	spindle localization	7/988	56/18722	0.0271995249710694	0.093275582082841	ITGB1/GJA1/MYH9/ACTR2/MAP4/DYNC1H1/WASL	7
GO:0071385	cellular response to glucocorticoid stimulus	7/988	56/18722	0.0271995249710694	0.093275582082841	EDN1/FOXO1/ZFP36L1/CFLAR/ZFP36/ZFP36L2/NR3C1	7
GO:1904645	response to amyloid-beta	7/988	56/18722	0.0271995249710694	0.093275582082841	FCGR2B/IGF1/RAMP3/APP/GJA1/FYN/CD36	7
GO:0002688	regulation of leukocyte chemotaxis	12/988	122/18722	0.0276420204308622	0.0943860491744917	EDN1/VEGFC/MTUS1/THBS1/MDK/DUSP1/JAM3/ADAM10/MOSPD2/WNK1/PTK2/MAPK1	12
GO:0051208	sequestering of calcium ion	12/988	122/18722	0.0276420204308622	0.0943860491744917	APLNR/F2R/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/ERO1A/ITPR2/HSP90B1/PKD2	12
GO:0099024	plasma membrane invagination	13/988	136/18722	0.0276824358943039	0.0943860491744917	FCGR2B/ITGA2/THBS1/ELMO1/MYH9/CD36/RHOA/GATA2/ABCA1/GSN/CLCN3/CDC42/DOCK1	13
GO:0002285	lymphocyte activation involved in immune response	17/988	194/18722	0.0280961710144365	0.0943860491744917	FCGR2B/HLX/CEACAM1/ITM2A/FOXP1/MFNG/CD81/LGALS1/MDK/TGFB1/LAMP1/RAB27A/STAT3/RC3H1/CD46/KMT5B/RIF1	17
GO:0035025	positive regulation of Rho protein signal transduction	5/988	33/18722	0.0281397101776694	0.0943860491744917	COL3A1/F2R/LPAR6/F11R/ARHGEF3	5
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	5/988	33/18722	0.0281397101776694	0.0943860491744917	TEK/PDGFB/TGFB1/CDC42/PTK2	5
GO:0061842	microtubule organizing center localization	5/988	33/18722	0.0281397101776694	0.0943860491744917	KIF5B/PLXNA2/SUN1/RANBP2/NIN	5
GO:0070570	regulation of neuron projection regeneration	5/988	33/18722	0.0281397101776694	0.0943860491744917	SCARF1/KLF4/PTEN/FLNA/MAP4K4	5
GO:1900181	negative regulation of protein localization to nucleus	5/988	33/18722	0.0281397101776694	0.0943860491744917	ANGPT1/PKIG/MDFIC/CD36/CTNNA1	5
GO:1902992	negative regulation of amyloid precursor protein catabolic process	5/988	33/18722	0.0281397101776694	0.0943860491744917	IGF1/CLU/RTN4/PICALM/ROCK1	5
GO:0003222	ventricular trabecula myocardium morphogenesis	3/988	13/18722	0.0281630060130966	0.0943860491744917	HEG1/ENG/NOTCH1	3
GO:0003334	keratinocyte development	3/988	13/18722	0.0281630060130966	0.0943860491744917	FLNB/PALLD/PLEC	3
GO:0008298	intracellular mRNA localization	3/988	13/18722	0.0281630060130966	0.0943860491744917	BICD1/ZFP36L1/ZFP36	3
GO:0014745	negative regulation of muscle adaptation	3/988	13/18722	0.0281630060130966	0.0943860491744917	FOXO1/KLF4/ATP2B4	3
GO:0014842	regulation of skeletal muscle satellite cell proliferation	3/988	13/18722	0.0281630060130966	0.0943860491744917	ANGPT1/CFLAR/STAT3	3
GO:0016246	RNA interference	3/988	13/18722	0.0281630060130966	0.0943860491744917	DICER1/ADAR/CELF1	3
GO:0016322	neuron remodeling	3/988	13/18722	0.0281630060130966	0.0943860491744917	SCARF1/APP/ANKS1A	3
GO:0031053	primary miRNA processing	3/988	13/18722	0.0281630060130966	0.0943860491744917	SMAD1/STAT3/SMAD2	3
GO:0031272	regulation of pseudopodium assembly	3/988	13/18722	0.0281630060130966	0.0943860491744917	CDC42EP5/APC/CDC42	3
GO:0031274	positive regulation of pseudopodium assembly	3/988	13/18722	0.0281630060130966	0.0943860491744917	CDC42EP5/APC/CDC42	3
GO:0033262	regulation of nuclear cell cycle DNA replication	3/988	13/18722	0.0281630060130966	0.0943860491744917	DACH1/ATRX/ZMPSTE24	3
GO:0036302	atrioventricular canal development	3/988	13/18722	0.0281630060130966	0.0943860491744917	ENG/TBX3/SMAD4	3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3/988	13/18722	0.0281630060130966	0.0943860491744917	CLIC2/CALM1/PKD2	3
GO:0060100	positive regulation of phagocytosis, engulfment	3/988	13/18722	0.0281630060130966	0.0943860491744917	ITGA2/CD36/GATA2	3
GO:0060347	heart trabecula formation	3/988	13/18722	0.0281630060130966	0.0943860491744917	TEK/ADGRG6/FKBP1A	3
GO:0060707	trophoblast giant cell differentiation	3/988	13/18722	0.0281630060130966	0.0943860491744917	SOCS3/NR2F2/HECTD1	3
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3/988	13/18722	0.0281630060130966	0.0943860491744917	NOTCH1/HIF1A/EGR1	3
GO:0070486	leukocyte aggregation	3/988	13/18722	0.0281630060130966	0.0943860491744917	JAM2/MSN/CD44	3
GO:0072672	neutrophil extravasation	3/988	13/18722	0.0281630060130966	0.0943860491744917	PECAM1/IL1R1/MDK	3
GO:0090042	tubulin deacetylation	3/988	13/18722	0.0281630060130966	0.0943860491744917	FRY/FLNA/PRKAA1	3
GO:0098814	spontaneous synaptic transmission	3/988	13/18722	0.0281630060130966	0.0943860491744917	ITGB1/APP/SLC12A2	3
GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	3/988	13/18722	0.0281630060130966	0.0943860491744917	GNAI2/PDE4B/ATP2B4	3
GO:1902947	regulation of tau-protein kinase activity	3/988	13/18722	0.0281630060130966	0.0943860491744917	CLU/RB1/EGR1	3
GO:1903054	negative regulation of extracellular matrix organization	3/988	13/18722	0.0281630060130966	0.0943860491744917	NOTCH1/TGFB1/TNFRSF1B	3
GO:1905155	positive regulation of membrane invagination	3/988	13/18722	0.0281630060130966	0.0943860491744917	ITGA2/CD36/GATA2	3
GO:1905203	regulation of connective tissue replacement	3/988	13/18722	0.0281630060130966	0.0943860491744917	PPP3CA/ROCK2/ROCK1	3
GO:0071214	cellular response to abiotic stimulus	26/988	331/18722	0.0283168886158044	0.0947821753794286	ITGA2/HYAL2/LRRC8C/ENG/PIEZO1/SLC38A2/IFI16/RHOB/ZFP36L1/TIMP1/CARD16/GJA1/TP53INP1/PIK3CA/PTEN/POLK/PKD2/EGR1/SLC2A1/CLOCK/F11R/PLEC/NIPBL/NEDD4/BCL10/ZMPSTE24	26
GO:0104004	cellular response to environmental stimulus	26/988	331/18722	0.0283168886158044	0.0947821753794286	ITGA2/HYAL2/LRRC8C/ENG/PIEZO1/SLC38A2/IFI16/RHOB/ZFP36L1/TIMP1/CARD16/GJA1/TP53INP1/PIK3CA/PTEN/POLK/PKD2/EGR1/SLC2A1/CLOCK/F11R/PLEC/NIPBL/NEDD4/BCL10/ZMPSTE24	26
GO:0031060	regulation of histone methylation	8/988	69/18722	0.0283831983750071	0.0949443008614848	NNMT/BCOR/KMT2E/ATRX/KMT2A/OGT/RIF1/SMAD4	8
GO:0043409	negative regulation of MAPK cascade	16/988	180/18722	0.0289392550293273	0.096743437832465	MECOM/HYAL2/CAV1/FOXO1/SH2B3/DUSP1/AIDA/DUSP6/KLF4/ZMYND11/PTEN/CYLD/HIPK3/ASH1L/SYNJ2BP/SMAD4	16
GO:0050684	regulation of mRNA processing	13/988	137/18722	0.0291676425131996	0.0974456081950417	NOVA2/ZFP36L1/DDX17/MBNL1/QKI/CELF1/SON/MBNL2/RBM5/DYRK1A/HNRNPK/TIA1/CCNT1	13
GO:0050852	T cell receptor signaling pathway	12/988	123/18722	0.0292193727723772	0.0975570761576792	CEACAM1/PDE4D/HLA-A/CD81/FYN/PIK3CA/PDE4B/RC3H1/CBLB/WNK1/MAPK1/BCL10	12
GO:0033619	membrane protein proteolysis	7/988	57/18722	0.029647452147846	0.0988000412856699	TIMP1/ERAP1/TGFB1/MYH9/ADAM10/TNFRSF1B/ROCK1	7
GO:0051155	positive regulation of striated muscle cell differentiation	7/988	57/18722	0.029647452147846	0.0988000412856699	EDN1/IGF1/EFNB2/MEF2C/PIEZO1/ATP11A/TGFB1	7
GO:0097120	receptor localization to synapse	7/988	57/18722	0.029647452147846	0.0988000412856699	KIF5B/STX3/ADAM10/NPTN/RAB11A/SYNJ2BP/RAP1A	7
GO:0006903	vesicle targeting	6/988	45/18722	0.0298938469874735	0.0991855810102806	EXOC6/MAP4K2/SNAP23/WDR11/FAM91A1/STARD3NL	6
GO:0035272	exocrine system development	6/988	45/18722	0.0298938469874735	0.0991855810102806	NFIB/PLXND1/IGF2/NRP1/TGFB1/CDC42	6
GO:0035305	negative regulation of dephosphorylation	6/988	45/18722	0.0298938469874735	0.0991855810102806	FKBP1A/GNAI2/ARPP19/ROCK2/ROCK1/YWHAB	6
GO:0035384	thioester biosynthetic process	6/988	45/18722	0.0298938469874735	0.0991855810102806	PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A	6
GO:0042551	neuron maturation	6/988	45/18722	0.0298938469874735	0.0991855810102806	SCARF1/AGRN/APP/ANKS1A/RB1/B4GALT5	6
GO:0071616	acyl-CoA biosynthetic process	6/988	45/18722	0.0298938469874735	0.0991855810102806	PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A	6
GO:1904646	cellular response to amyloid-beta	6/988	45/18722	0.0298938469874735	0.0991855810102806	FCGR2B/IGF1/APP/GJA1/FYN/CD36	6
GO:0006479	protein methylation	16/988	181/18722	0.0302554608295612	0.100197635864482	NNMT/MECOM/BCOR/KMT2E/ATRX/KMT2A/OGT/FBXO11/PCMTD1/ASH1L/WDR82/KMT5B/RIF1/PCMTD2/BTG2/SMAD4	16
GO:0008213	protein alkylation	16/988	181/18722	0.0302554608295612	0.100197635864482	NNMT/MECOM/BCOR/KMT2E/ATRX/KMT2A/OGT/FBXO11/PCMTD1/ASH1L/WDR82/KMT5B/RIF1/PCMTD2/BTG2/SMAD4	16
GO:0099504	synaptic vesicle cycle	16/988	181/18722	0.0302554608295612	0.100197635864482	P2RY1/SYT11/CANX/GIT1/CALM1/ITSN2/STX3/PTEN/KIAA1109/SNAP23/PICALM/CTBP2/CLCN3/ROCK1/RAB5A/RAP1A	16
GO:0051092	positive regulation of NF-kappaB transcription factor activity	14/988	152/18722	0.030294096501298	0.100263078264732	CAV1/CLU/MTDH/CARD16/APP/PRKCH/CFLAR/CD36/STAT3/EIF2AK2/CLOCK/TRIM13/HSPA1A/BCL10	14
GO:0031397	negative regulation of protein ubiquitination	9/988	83/18722	0.0305933450180803	0.10075554601083	NXN/CAV1/PRKCE/FYN/ISG15/OGT/DTX3L/TRIP12/HSPA1A	9
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	4/988	23/18722	0.0306136015175978	0.10075554601083	F2R/RPS6KA2/PCSK5/RHOA	4
GO:0021884	forebrain neuron development	4/988	23/18722	0.0306136015175978	0.10075554601083	NDNF/NRP1/ZMIZ1/RAPGEF2	4
GO:0030194	positive regulation of blood coagulation	4/988	23/18722	0.0306136015175978	0.10075554601083	F2R/THBD/THBS1/CD36	4
GO:0035994	response to muscle stretch	4/988	23/18722	0.0306136015175978	0.10075554601083	EDN1/PIK3CA/GSN/PTK2	4
GO:0036119	response to platelet-derived growth factor	4/988	23/18722	0.0306136015175978	0.10075554601083	YES1/FYN/RDX/CREB1	4
GO:0045662	negative regulation of myoblast differentiation	4/988	23/18722	0.0306136015175978	0.10075554601083	ID3/NOTCH1/TGFB1/TBX3	4
GO:0051457	maintenance of protein location in nucleus	4/988	23/18722	0.0306136015175978	0.10075554601083	PML/SUN1/SP100/ARL2BP	4
GO:1900048	positive regulation of hemostasis	4/988	23/18722	0.0306136015175978	0.10075554601083	F2R/THBD/THBS1/CD36	4
GO:0060047	heart contraction	20/988	241/18722	0.0306565117831996	0.100834297580407	EDN1/RPS6KA2/CAV1/PDE4D/CLIC2/EPAS1/THRA/SMAD5/MEF2A/ADRB1/CALM1/GJA1/PIK3CA/PDE4B/FLNA/ATP2B4/GJA5/GSN/CDC42/ZMPSTE24	20
GO:0032273	positive regulation of protein polymerization	13/988	138/18722	0.0307100325837078	0.100947829879119	CDC42EP5/PRKCE/GIT1/NCKAP1/ACTR2/RHOA/ABI2/CTTN/MYO1C/GSN/WASL/HSPA1A/NIN	13
GO:0002703	regulation of leukocyte mediated immunity	19/988	226/18722	0.0307735324953518	0.1010940040911	FCGR2B/BST2/CEACAM1/FOXF1/IL1R1/HLA-E/HLA-A/AHR/HLA-B/B2M/CD81/TGFB1/LAMP1/GATA2/TNFRSF1B/CRK/CD46/KMT5B/RIF1	19
GO:0140014	mitotic nuclear division	23/988	287/18722	0.0307959088312622	0.101104986224762	EDN1/IGF1/HOXA13/CAV2/IGF2/RGCC/PDGFB/RB1/DUSP1/ATRX/PDS5B/SLF2/POGZ/FLNA/RHOA/APC/STAG2/CDC27/PHIP/NIPBL/RAB11A/CDC42/HSPA1A	23
GO:0001909	leukocyte mediated cytotoxicity	12/988	124/18722	0.0308607411056813	0.101192751082333	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/B2M/KIF5B/LYST/LAMP1/RAB27A/EMP2/CRK	12
GO:0007368	determination of left/right symmetry	12/988	124/18722	0.0308607411056813	0.101192751082333	APLNR/SOX18/FOXF1/MEF2C/ENG/NOTCH1/TGFBR2/MIB1/HIF1A/PKD2/TBX3/SMAD2	12
GO:0007431	salivary gland development	5/988	34/18722	0.0316055578708266	0.103062445309902	NFIB/PLXND1/NRP1/TGFB1/CDC42	5
GO:0010614	negative regulation of cardiac muscle hypertrophy	5/988	34/18722	0.0316055578708266	0.103062445309902	FOXO1/NOTCH1/ATP2B4/TNFRSF1B/SMAD4	5
GO:0010922	positive regulation of phosphatase activity	5/988	34/18722	0.0316055578708266	0.103062445309902	ITGA2/MEF2C/ITGA1/CALM1/PPP1R12A	5
GO:0035909	aorta morphogenesis	5/988	34/18722	0.0316055578708266	0.103062445309902	ACVRL1/ENG/JAG1/NOTCH1/HES1	5
GO:0048741	skeletal muscle fiber development	5/988	34/18722	0.0316055578708266	0.103062445309902	CAV2/RCAN1/SKI/PPP3CA/PLEC	5
GO:0055094	response to lipoprotein particle	5/988	34/18722	0.0316055578708266	0.103062445309902	ITGB1/CD81/CD36/ABCA1/CD9	5
GO:0070884	regulation of calcineurin-NFAT signaling cascade	5/988	34/18722	0.0316055578708266	0.103062445309902	IGF1/LMCD1/RCAN1/NFAT5/ATP2B4	5
GO:0090075	relaxation of muscle	5/988	34/18722	0.0316055578708266	0.103062445309902	P2RY1/PDE4D/PIK3CA/PDE4B/GSN	5
GO:1904893	negative regulation of receptor signaling pathway via STAT	5/988	34/18722	0.0316055578708266	0.103062445309902	CAV1/SH2B3/SOCS3/PARP14/LEPROT	5
GO:1904951	positive regulation of establishment of protein localization	25/988	319/18722	0.0318055528604944	0.103650979628801	IGF1/VEGFC/ABLIM3/NNAT/HYAL2/PRKCE/CD81/KIF5B/STOM/TGFB1/GJA1/FYN/ACSL3/FLNA/HIF1A/PCM1/MYO1C/RUFY3/LEPROT/PRKAA1/SH3GLB1/CDC42/MAPK1/OAZ2/CTDSPL2	25
GO:0043255	regulation of carbohydrate biosynthetic process	10/988	97/18722	0.0318688970779437	0.10379373468917	IGF1/NNMT/LEPR/P2RY1/IGF2/PDGFB/TGFB1/RANBP2/OGT/ARPP19	10
GO:0043523	regulation of neuron apoptotic process	18/988	212/18722	0.0320309086941733	0.104257467514368	NDNF/F2R/MEF2C/ITGA1/ANGPT1/NRP1/HIPK2/MDK/FYN/PIK3CA/MAP3K11/RHOA/HIF1A/ATF2/GBE1/CDC42/BTG2/JUN	18
GO:0002763	positive regulation of myeloid leukocyte differentiation	7/988	58/18722	0.0322395756242746	0.104744113587857	ZFP36L1/RB1/TGFB1/CREB1/KLF10/ID2/JUN	7
GO:0018208	peptidyl-proline modification	7/988	58/18722	0.0322395756242746	0.104744113587857	FKBP1A/FKBP9/ERO1A/EGLN1/RANBP2/NKTR/CRTAP	7
GO:0043506	regulation of JUN kinase activity	7/988	58/18722	0.0322395756242746	0.104744113587857	EDN1/FZD4/MAP4K2/SASH1/AIDA/MAP3K11/HIPK3	7
GO:0045861	negative regulation of proteolysis	27/988	351/18722	0.0324507211610716	0.105365666752819	A2M/BST2/CD109/PROS1/TFPI2/TFPI/THBS1/IFI16/RPS6KA3/TIMP1/CRIM1/CARD16/HIPK2/APP/XIAP/PML/CARD8/KLF4/SERPINH1/OGT/RYBP/SDCBP/PICALM/CD44/PAK2/WAC/ROCK1	27
GO:0006112	energy reserve metabolic process	9/988	84/18722	0.0327252181356857	0.105997779717538	IGF1/ADGRF5/KL/LEPR/PCDH12/IGF2/IL6ST/RB1CC1/GBE1	9
GO:0006970	response to osmotic stress	9/988	84/18722	0.0327252181356857	0.105997779717538	ITGA2/LRRC8C/ZFP36L1/SLC12A2/PKN1/NFAT5/PKD2/SLC2A1/ATF2	9
GO:0022404	molting cycle process	9/988	84/18722	0.0327252181356857	0.105997779717538	LDB2/SOX18/CD109/NOTCH1/FZD6/SOS1/SMAD4/SAV1/ZMPSTE24	9
GO:0022405	hair cycle process	9/988	84/18722	0.0327252181356857	0.105997779717538	LDB2/SOX18/CD109/NOTCH1/FZD6/SOS1/SMAD4/SAV1/ZMPSTE24	9
GO:0032924	activin receptor signaling pathway	6/988	46/18722	0.0328992240325944	0.106366815618467	ACVRL1/BMPR2/FKBP1A/TGFBR2/SKI/SMAD2	6
GO:0055010	ventricular cardiac muscle tissue morphogenesis	6/988	46/18722	0.0328992240325944	0.106366815618467	HEG1/ENG/FKBP1A/NOTCH1/TGFB1/SMAD4	6
GO:0061462	protein localization to lysosome	6/988	46/18722	0.0328992240325944	0.106366815618467	CLU/CD81/SCARB2/RTN4/ROCK2/NEDD4	6
GO:0000281	mitotic cytokinesis	8/988	71/18722	0.0329763912023289	0.106421986674831	SPTBN1/RHOB/RHOA/SON/APC/PDCD6IP/ROCK2/ROCK1	8
GO:0033555	multicellular organismal response to stress	8/988	71/18722	0.0329763912023289	0.106421986674831	MEF2C/THBS1/MDK/ADRB1/GJA1/PTEN/CAPN2/PPP3CA	8
GO:0061515	myeloid cell development	8/988	71/18722	0.0329763912023289	0.106421986674831	ADGRF5/FLI1/FOXP1/KLF2/SH2B3/APP/TMOD3/PTBP3	8
GO:0002467	germinal center formation	3/988	14/18722	0.0344689809765206	0.110300739124866	MEF2C/PKN1/RC3H1	3
GO:0002517	T cell tolerance induction	3/988	14/18722	0.0344689809765206	0.110300739124866	HLA-B/TGFBR2/CBLB	3
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	3/988	14/18722	0.0344689809765206	0.110300739124866	MMRN2/HHEX/NEDD4	3
GO:0031115	negative regulation of microtubule polymerization	3/988	14/18722	0.0344689809765206	0.110300739124866	CDH5/ARHGEF7/DYRK1A	3
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	3/988	14/18722	0.0344689809765206	0.110300739124866	HIP1/PDGFB/PTPN12	3
GO:0035815	positive regulation of renal sodium excretion	3/988	14/18722	0.0344689809765206	0.110300739124866	EDN1/NPR1/GNAI2	3
GO:0036295	cellular response to increased oxygen levels	3/988	14/18722	0.0344689809765206	0.110300739124866	CAV1/FOXO1/ATP6V1A	3
GO:0038166	angiotensin-activated signaling pathway	3/988	14/18722	0.0344689809765206	0.110300739124866	CAV1/ROCK2/ROCK1	3
GO:0044764	multi-organism cellular process	3/988	14/18722	0.0344689809765206	0.110300739124866	HYAL2/CAV1/CAV2	3
GO:0051589	negative regulation of neurotransmitter transport	3/988	14/18722	0.0344689809765206	0.110300739124866	SYT11/SLC30A1/RAP1A	3
GO:0072160	nephron tubule epithelial cell differentiation	3/988	14/18722	0.0344689809765206	0.110300739124866	WWTR1/MEF2C/MTSS1	3
GO:1900037	regulation of cellular response to hypoxia	3/988	14/18722	0.0344689809765206	0.110300739124866	CD34/TMBIM6/ROCK2	3
GO:1901722	regulation of cell proliferation involved in kidney development	3/988	14/18722	0.0344689809765206	0.110300739124866	PDGFB/CFLAR/EGR1	3
GO:1902036	regulation of hematopoietic stem cell differentiation	3/988	14/18722	0.0344689809765206	0.110300739124866	TCF15/N4BP2L2/EIF2AK2	3
GO:0010970	transport along microtubule	14/988	155/18722	0.034954823198887	0.111236823963106	BICD1/DST/KIF5B/APP/ARMCX3/LAMP1/SUN1/HIF1A/PURA/PCM1/KIF1B/DYNC1H1/CDC42/KIFAP3	14
GO:0055013	cardiac muscle cell development	9/988	85/18722	0.0349577303632788	0.111236823963106	EDN1/IGF1/SORBS2/MEF2A/PDLIM5/TBX3/PLEC/SMAD4/ZMPSTE24	9
GO:0072384	organelle transport along microtubule	9/988	85/18722	0.0349577303632788	0.111236823963106	BICD1/KIF5B/ARMCX3/LAMP1/SUN1/HIF1A/DYNC1H1/CDC42/KIFAP3	9
GO:0098773	skin epidermis development	9/988	85/18722	0.0349577303632788	0.111236823963106	LDB2/SOX18/CD109/NOTCH1/FZD6/SOS1/SMAD4/SAV1/ZMPSTE24	9
GO:0001783	B cell apoptotic process	4/988	24/18722	0.0352484599567736	0.111236823963106	FOXP1/PKN1/PTEN/BCL10	4
GO:0002726	positive regulation of T cell cytokine production	4/988	24/18722	0.0352484599567736	0.111236823963106	IL1R1/HLA-A/B2M/CD81	4
GO:0010288	response to lead ion	4/988	24/18722	0.0352484599567736	0.111236823963106	SPARC/APP/PLSCR1/PPP2CB	4
GO:0032528	microvillus organization	4/988	24/18722	0.0352484599567736	0.111236823963106	PODXL/FSCN1/FXYD5/RAPGEF2	4
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	4/988	24/18722	0.0352484599567736	0.111236823963106	KLF2/NOTCH1/HIF1A/ATF6	4
GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	4/988	24/18722	0.0352484599567736	0.111236823963106	SEC14L1/DDX60/TSPAN6/PUM2	4
GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	4/988	24/18722	0.0352484599567736	0.111236823963106	IGFBP4/IGF1/IGFBP3/PHIP	4
GO:0045649	regulation of macrophage differentiation	4/988	24/18722	0.0352484599567736	0.111236823963106	RB1/TGFB1/GATA2/ID2	4
GO:0048641	regulation of skeletal muscle tissue development	4/988	24/18722	0.0352484599567736	0.111236823963106	MEF2C/IGF2/TGFB1/PRKAA1	4
GO:0050687	negative regulation of defense response to virus	4/988	24/18722	0.0352484599567736	0.111236823963106	SEC14L1/TSPAN6/HTRA1/PCBP2	4
GO:0050820	positive regulation of coagulation	4/988	24/18722	0.0352484599567736	0.111236823963106	F2R/THBD/THBS1/CD36	4
GO:0051647	nucleus localization	4/988	24/18722	0.0352484599567736	0.111236823963106	SUN1/PCM1/DYNC1H1/CDC42	4
GO:1903077	negative regulation of protein localization to plasma membrane	4/988	24/18722	0.0352484599567736	0.111236823963106	PPP2R5A/TGFB1/PICALM/HECTD1	4
GO:2000679	positive regulation of transcription regulatory region DNA binding	4/988	24/18722	0.0352484599567736	0.111236823963106	IGF1/RB1/TGFB1/KLF4	4
GO:0002429	immune response-activating cell surface receptor signaling pathway	23/988	291/18722	0.0352549065855906	0.111236823963106	FCGR2B/CEACAM1/MEF2C/PDE4D/FOXP1/PRKCE/HLA-A/CD81/YES1/PRKCH/FYN/PIK3CA/PDE4B/CMTM3/PLSCR1/RC3H1/PAK2/CBLB/WNK1/PTK2/MAPK1/BCL10/RAP1A	23
GO:0002757	immune response-activating signal transduction	23/988	291/18722	0.0352549065855906	0.111236823963106	FCGR2B/CEACAM1/MEF2C/PDE4D/FOXP1/PRKCE/HLA-A/CD81/YES1/PRKCH/FYN/PIK3CA/PDE4B/CMTM3/PLSCR1/RC3H1/PAK2/CBLB/WNK1/PTK2/MAPK1/BCL10/RAP1A	23
GO:0016236	macroautophagy	23/988	291/18722	0.0352549065855906	0.111236823963106	KDR/SPTLC2/FEZ2/CALM1/TP53INP1/QSOX1/PIK3CA/HIF1A/RALB/ATP6V1A/RB1CC1/VPS13C/NBR1/TRIM13/WAC/WDFY3/SH3GLB1/SMG1/NEDD4/RAB5A/VPS36/CAPNS1/PAFAH1B2	23
GO:0001893	maternal placenta development	5/988	35/18722	0.0353269055018375	0.111236823963106	BMPR2/GJA1/NR2F2/ASH1L/MAPK1	5
GO:0034331	cell junction maintenance	5/988	35/18722	0.0353269055018375	0.111236823963106	F2R/TJP1/FERMT2/CTBP2/MTSS1	5
GO:0045907	positive regulation of vasoconstriction	5/988	35/18722	0.0353269055018375	0.111236823963106	F2R/CAV1/GJA1/RHOA/GJA5	5
GO:0048821	erythrocyte development	5/988	35/18722	0.0353269055018375	0.111236823963106	ADGRF5/KLF2/SH2B3/TMOD3/PTBP3	5
GO:0106056	regulation of calcineurin-mediated signaling	5/988	35/18722	0.0353269055018375	0.111236823963106	IGF1/LMCD1/RCAN1/NFAT5/ATP2B4	5
GO:1905898	positive regulation of response to endoplasmic reticulum stress	5/988	35/18722	0.0353269055018375	0.111236823963106	FCGR2B/CAV1/SERINC3/ATXN3/ATF6	5
GO:0035567	non-canonical Wnt signaling pathway	8/988	72/18722	0.0354523169201496	0.111565584999902	RSPO3/FZD4/SMURF2/RHOA/FZD6/DAAM1/CDC42/RNF213	8
GO:0030595	leukocyte chemotaxis	19/988	230/18722	0.0358705947059737	0.112815037938503	EDN1/S1PR1/VEGFC/MTUS1/ITGA1/THBS1/PDGFB/MDK/SLC12A2/DUSP1/JAM3/LYST/PDE4B/ADAM10/MOSPD2/PLEC/WNK1/PTK2/MAPK1	19
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	10/988	99/18722	0.0359818260276938	0.112915393968937	IFI16/SKIL/FNIP2/CLU/HIPK2/PML/HIPK1/CD44/TNFRSF1B/HNRNPK	10
GO:0030838	positive regulation of actin filament polymerization	10/988	99/18722	0.0359818260276938	0.112915393968937	CDC42EP5/PRKCE/NCKAP1/ACTR2/RHOA/ABI2/CTTN/MYO1C/GSN/WASL	10
GO:0007595	lactation	6/988	47/18722	0.0360938138101007	0.112915393968937	CAV1/PAM/OAS2/HIF1A/CREB1/CCND1	6
GO:0046677	response to antibiotic	6/988	47/18722	0.0360938138101007	0.112915393968937	HYAL2/MEF2C/JAK1/CPT1A/ACTR2/PPP2CB	6
GO:0048483	autonomic nervous system development	6/988	47/18722	0.0360938138101007	0.112915393968937	HLX/FN1/NRP1/PHACTR4/SEMA3F/HES1	6
GO:0050798	activated T cell proliferation	6/988	47/18722	0.0360938138101007	0.112915393968937	IGF1/LRRC32/IGF2/PRKAR1A/FYN/RC3H1	6
GO:0101023	vascular endothelial cell proliferation	6/988	47/18722	0.0360938138101007	0.112915393968937	MEF2C/FGFR1/IGF2/MDK/AKT3/STAT3	6
GO:0120163	negative regulation of cold-induced thermogenesis	6/988	47/18722	0.0360938138101007	0.112915393968937	LAMA4/NOVA2/ID1/NOTCH1/RB1/LNPEP	6
GO:1905562	regulation of vascular endothelial cell proliferation	6/988	47/18722	0.0360938138101007	0.112915393968937	MEF2C/FGFR1/IGF2/MDK/AKT3/STAT3	6
GO:0006911	phagocytosis, engulfment	12/988	127/18722	0.0361811880411234	0.113122113522335	FCGR2B/ITGA2/THBS1/ELMO1/MYH9/CD36/GATA2/ABCA1/GSN/CLCN3/CDC42/DOCK1	12
GO:0008544	epidermis development	25/988	324/18722	0.0372634948015681	0.116437461403488	EMP1/LDB2/SOX18/CD109/JAG1/FABP5/TXNIP/NOTCH1/UGCG/ZFP36L1/FLNB/PRKCH/KLF4/PALLD/ZFP36/CLIC4/FZD6/PLEC/HES1/ROCK2/ROCK1/SOS1/SMAD4/SAV1/ZMPSTE24	25
GO:2000117	negative regulation of cysteine-type endopeptidase activity	9/988	86/18722	0.0372927339608988	0.116460319106581	THBS1/IFI16/RPS6KA3/CARD16/XIAP/CARD8/KLF4/CD44/PAK2	9
GO:0050729	positive regulation of inflammatory response	13/988	142/18722	0.037472716936513	0.116922465107509	FABP4/IL33/ITGA2/HYAL2/ETS1/HLA-E/OSMR/MGST2/CD81/APP/MDK/IL6ST/CLOCK	13
GO:0071706	tumor necrosis factor superfamily cytokine production	16/988	186/18722	0.0375067546203304	0.116922465107509	CD34/IGF1/IL33/FOXP1/SYT11/HLA-E/THBS1/ANGPT1/CLU/APP/DICER1/OAS2/CD36/ZFP36/STAT3/BCL10	16
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	16/988	186/18722	0.0375067546203304	0.116922465107509	CD34/IGF1/IL33/FOXP1/SYT11/HLA-E/THBS1/ANGPT1/CLU/APP/DICER1/OAS2/CD36/ZFP36/STAT3/BCL10	16
GO:0010466	negative regulation of peptidase activity	21/988	262/18722	0.0376929604380847	0.117434021024696	A2M/BST2/CD109/PROS1/TFPI2/TFPI/THBS1/IFI16/RPS6KA3/TIMP1/CRIM1/CARD16/APP/XIAP/CARD8/KLF4/SERPINH1/PICALM/CD44/PAK2/ROCK1	21
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	7/988	60/18722	0.0378678920064905	0.117565308204838	NOVA2/DDX17/MBNL1/CELF1/MBNL2/RBM5/DYRK1A	7
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	7/988	60/18722	0.0378678920064905	0.117565308204838	SEC14L1/DDX60/TSPAN6/XIAP/CYLD/PUM2/HSPA1A	7
GO:0033866	nucleoside bisphosphate biosynthetic process	7/988	60/18722	0.0378678920064905	0.117565308204838	PAPSS2/PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A	7
GO:0034030	ribonucleoside bisphosphate biosynthetic process	7/988	60/18722	0.0378678920064905	0.117565308204838	PAPSS2/PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A	7
GO:0034033	purine nucleoside bisphosphate biosynthetic process	7/988	60/18722	0.0378678920064905	0.117565308204838	PAPSS2/PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A	7
GO:0055008	cardiac muscle tissue morphogenesis	7/988	60/18722	0.0378678920064905	0.117565308204838	HEG1/S1PR1/ENG/FKBP1A/NOTCH1/TGFB1/SMAD4	7
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	8/988	73/18722	0.038050767516347	0.117926299327208	CEACAM1/HIP1/ITGA1/CCDC88A/SOCS4/CBLB/SOS1/PTPN12	8
GO:0043299	leukocyte degranulation	8/988	73/18722	0.038050767516347	0.117926299327208	FCGR2B/CEACAM1/FOXF1/LAMP1/RAB27A/GATA2/SNAP23/S100A13	8
GO:0086003	cardiac muscle cell contraction	8/988	73/18722	0.038050767516347	0.117926299327208	CAV1/PDE4D/GJA1/PIK3CA/PDE4B/FLNA/GJA5/GSN	8
GO:0061640	cytoskeleton-dependent cytokinesis	10/988	100/18722	0.0381705604549666	0.118228581420864	SPTBN1/RHOB/ACTR2/RHOA/SON/APC/PLEC/PDCD6IP/ROCK2/ROCK1	10
GO:0007034	vacuolar transport	14/988	157/18722	0.0383360283284453	0.11860278537024	RHOB/CLU/LEPROTL1/SCARB2/LYST/LAMP1/TMEM50B/VPS13C/LEPROT/DTX3L/TMEM50A/HSPA1A/NEDD4/VPS36	14
GO:2000377	regulation of reactive oxygen species metabolic process	14/988	157/18722	0.0383360283284453	0.11860278537024	PRCP/THBS1/TGFBR2/PDGFB/GNAI2/TGFB1/CFLAR/FYN/CD36/RAB27A/RHOA/HIF1A/STAT3/CLCN3	14
GO:0051261	protein depolymerization	11/988	114/18722	0.0383702563779624	0.118639582002175	SPTBN1/SPTAN1/TAOK1/PIK3CA/TMOD3/RDX/ADD1/APC/GSN/DSTN/CAMSAP2	11
GO:0002221	pattern recognition receptor signaling pathway	15/988	172/18722	0.0388548639064369	0.120068084392666	CAV1/PRKCE/SEC14L1/RPS6KA3/DDX60/TSPAN6/XIAP/CD36/CYLD/RTN4/WDFY1/PJA2/PUM2/HSPA1A/BCL10	15
GO:0010948	negative regulation of cell cycle process	23/988	294/18722	0.0389033280964093	0.120147952818678	RPS6KA2/RGCC/ZFP36L1/RB1/DUSP1/PML/TAOK1/ATRX/PRKAR1A/KLF4/PTEN/CTDSP2/PKD2/FEM1B/APC/CLOCK/CCND1/ZFP36L2/CTDSP1/WAC/ATF2/FOXN3/PLK2	23
GO:0072503	cellular divalent inorganic cation homeostasis	35/988	486/18722	0.0389515988751201	0.120227131449528	APLNR/CDH5/EDN1/LRP6/S1PR1/RAMP3/P2RY1/F2R/LPAR6/CAV1/CAV2/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/APP/CALM1/PML/GJA1/GNB1/FYN/STIM2/GTF2I/ERO1A/ITPR2/CD36/HSP90B1/TMBIM6/GATA2/SLC30A1/NPTN/PKD2/SLC30A7/ATP2B4	35
GO:0009913	epidermal cell differentiation	17/988	202/18722	0.0391134370970329	0.120656549279581	CD109/JAG1/TXNIP/NOTCH1/UGCG/ZFP36L1/FLNB/PRKCH/KLF4/PALLD/ZFP36/CLIC4/PLEC/HES1/ROCK2/ROCK1/SAV1	17
GO:0014741	negative regulation of muscle hypertrophy	5/988	36/18722	0.0393074126442524	0.121044044038417	FOXO1/NOTCH1/ATP2B4/TNFRSF1B/SMAD4	5
GO:0036314	response to sterol	5/988	36/18722	0.0393074126442524	0.121044044038417	LRP6/TGFBR2/TGFB1/ABCA1/SMAD2	5
GO:0071402	cellular response to lipoprotein particle stimulus	5/988	36/18722	0.0393074126442524	0.121044044038417	ITGB1/CD81/CD36/ABCA1/CD9	5
GO:0002715	regulation of natural killer cell mediated immunity	6/988	48/18722	0.0394807306404324	0.121156349602528	CEACAM1/HLA-E/HLA-A/HLA-B/LAMP1/CRK	6
GO:0033628	regulation of cell adhesion mediated by integrin	6/988	48/18722	0.0394807306404324	0.121156349602528	PODXL/PIEZO1/JAM3/CRK/WNK1/PTK2	6
GO:0048146	positive regulation of fibroblast proliferation	6/988	48/18722	0.0394807306404324	0.121156349602528	IGF1/FN1/PDGFB/CDK6/PML/ZMIZ1	6
GO:0061647	histone H3-K9 modification	6/988	48/18722	0.0394807306404324	0.121156349602528	MECOM/ATRX/KMT2A/ASH1L/RIF1/SMAD4	6
GO:1902003	regulation of amyloid-beta formation	6/988	48/18722	0.0394807306404324	0.121156349602528	IGF1/CLU/RTN4/PICALM/ROCK2/ROCK1	6
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	6/988	48/18722	0.0394807306404324	0.121156349602528	HIPK2/PML/OGT/RYBP/SDCBP/WAC	6
GO:1900182	positive regulation of protein localization to nucleus	9/988	87/18722	0.039731980052688	0.121856973464133	HYAL2/WWTR1/TGFB1/FYN/FLNA/FERMT2/PARP9/DTX3L/MAPK1	9
GO:0030098	lymphocyte differentiation	28/988	374/18722	0.0400399110980284	0.122717508183502	FCGR2B/LEPR/HLX/ITM2A/HHEX/FOXP1/TGFBR2/ITGB1/MFNG/B2M/ZFP36L1/LGALS1/MDK/LYL1/RHOA/STAT3/KLF6/ZMIZ1/EGR1/RC3H1/HECTD1/IRF2BP2/ZFP36L2/CD46/ATF2/SOS2/SOS1/ID2	28
GO:0010842	retina layer formation	4/988	25/18722	0.0402666823727117	0.122717508183502	TSPAN12/HIPK2/PTPRM/HIPK1	4
GO:0031579	membrane raft organization	4/988	25/18722	0.0402666823727117	0.122717508183502	CAV1/CAV2/EMP2/GSN	4
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	4/988	25/18722	0.0402666823727117	0.122717508183502	SASH1/CARD16/CARD8/CD36	4
GO:0032469	endoplasmic reticulum calcium ion homeostasis	4/988	25/18722	0.0402666823727117	0.122717508183502	ITPR1/APP/PML/TMBIM6	4
GO:0033119	negative regulation of RNA splicing	4/988	25/18722	0.0402666823727117	0.122717508183502	TMBIM6/PTBP3/DYRK1A/HNRNPK	4
GO:0035336	long-chain fatty-acyl-CoA metabolic process	4/988	25/18722	0.0402666823727117	0.122717508183502	ACSL3/ELOVL5/HSD17B12/FAR1	4
GO:0050927	positive regulation of positive chemotaxis	4/988	25/18722	0.0402666823727117	0.122717508183502	KDR/S1PR1/VEGFC/ITGA2	4
GO:0072202	cell differentiation involved in metanephros development	4/988	25/18722	0.0402666823727117	0.122717508183502	CD34/WWTR1/LAMB2/PDGFB	4
GO:0090312	positive regulation of protein deacetylation	4/988	25/18722	0.0402666823727117	0.122717508183502	APLNR/NNMT/NIPBL/DYRK1A	4
GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	4/988	25/18722	0.0402666823727117	0.122717508183502	TGFB1/STAT3/PPP3CA/ZMPSTE24	4
GO:0042102	positive regulation of T cell proliferation	10/988	101/18722	0.0404494454223396	0.123130411501986	IGF1/HLA-E/HLA-A/TGFBR2/IGF2/CD81/EFNB1/IL6ST/CD46/HES1	10
GO:0045088	regulation of innate immune response	18/988	218/18722	0.0404550173263396	0.123130411501986	A2M/FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/IFI16/XIAP/ERAP1/FYN/PARP14/LAMP1/ISG15/ADAR/PARP9/PLSCR1/PAK2/CRK	18
GO:0051209	release of sequestered calcium ion into cytosol	11/988	115/18722	0.0404948849574489	0.123130411501986	APLNR/F2R/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/ERO1A/ITPR2/PKD2	11
GO:1901989	positive regulation of cell cycle phase transition	11/988	115/18722	0.0404948849574489	0.123130411501986	PLCB1/RGCC/KMT2E/APP/RB1/CDC25B/TMOD3/RDX/CCND1/CDC27/RAB11A	11
GO:0070972	protein localization to endoplasmic reticulum	8/988	74/18722	0.0407737811165948	0.123907508747913	SPCS3/TRAM1/GJA1/SEC62/BCAP29/MAN1A1/RTN4/SEC61A1	8
GO:0034113	heterotypic cell-cell adhesion	7/988	61/18722	0.0409092234940675	0.124106108052819	ITGA5/ITGB1/JAM3/CD200/KLF4/CD44/WNK1	7
GO:0043030	regulation of macrophage activation	7/988	61/18722	0.0409092234940675	0.124106108052819	FCGR2B/IL33/ADGRF5/SYT11/THBS1/CD200/PJA2	7
GO:0071384	cellular response to corticosteroid stimulus	7/988	61/18722	0.0409092234940675	0.124106108052819	EDN1/FOXO1/ZFP36L1/CFLAR/ZFP36/ZFP36L2/NR3C1	7
GO:1901988	negative regulation of cell cycle phase transition	20/988	249/18722	0.0410140050666771	0.124352965133669	RGCC/ZFP36L1/RB1/DUSP1/PML/TAOK1/KLF4/PTEN/CTDSP2/PKD2/FEM1B/APC/CLOCK/CCND1/ZFP36L2/CTDSP1/WAC/ATF2/FOXN3/PLK2	20
GO:0034655	nucleobase-containing compound catabolic process	30/988	407/18722	0.0410628895729889	0.124362616961379	VIM/NT5E/PDE4D/ENTPD1/ZFP36L1/DICER1/PABPC1/OAS2/NUDT3/PDE4B/ZFP36/CSDE1/TNRC6B/CELF1/ACAT1/CNOT6L/ZC3HAV1/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/PUM2/ROCK2/SMG1/TNRC6A/ROCK1/CNOT2/HSPA1A/XRN1/BTG2	30
GO:0033135	regulation of peptidyl-serine phosphorylation	13/988	144/18722	0.0412240836869313	0.124362616961379	RAMP3/CAV1/PDE4D/ANGPT1/PPM1F/FNIP2/APP/TGFB1/PIK3CA/PTEN/ATP2B4/CD44/PRKAA1	13
GO:0014841	skeletal muscle satellite cell proliferation	3/988	15/18722	0.0414385978956401	0.124362616961379	ANGPT1/CFLAR/STAT3	3
GO:0014857	regulation of skeletal muscle cell proliferation	3/988	15/18722	0.0414385978956401	0.124362616961379	ANGPT1/CFLAR/STAT3	3
GO:0019511	peptidyl-proline hydroxylation	3/988	15/18722	0.0414385978956401	0.124362616961379	ERO1A/EGLN1/CRTAP	3
GO:0031269	pseudopodium assembly	3/988	15/18722	0.0414385978956401	0.124362616961379	CDC42EP5/APC/CDC42	3
GO:0032897	negative regulation of viral transcription	3/988	15/18722	0.0414385978956401	0.124362616961379	IFITM3/ZFP36/TRIM13	3
GO:0045475	locomotor rhythm	3/988	15/18722	0.0414385978956401	0.124362616961379	PTEN/EGR1/ID2	3
GO:0046007	negative regulation of activated T cell proliferation	3/988	15/18722	0.0414385978956401	0.124362616961379	LRRC32/PRKAR1A/RC3H1	3
GO:0051284	positive regulation of sequestering of calcium ion	3/988	15/18722	0.0414385978956401	0.124362616961379	CLIC2/CALM1/PKD2	3
GO:0060099	regulation of phagocytosis, engulfment	3/988	15/18722	0.0414385978956401	0.124362616961379	ITGA2/CD36/GATA2	3
GO:0070831	basement membrane assembly	3/988	15/18722	0.0414385978956401	0.124362616961379	RAMP2/LAMB2/PHLDB2	3
GO:0071380	cellular response to prostaglandin E stimulus	3/988	15/18722	0.0414385978956401	0.124362616961379	PRKCE/GNB1/PRKAA1	3
GO:0150011	regulation of neuron projection arborization	3/988	15/18722	0.0414385978956401	0.124362616961379	FZD4/MACF1/MYO9A	3
GO:1903727	positive regulation of phospholipid metabolic process	3/988	15/18722	0.0414385978956401	0.124362616961379	ADGRF5/ACSL3/CAPN2	3
GO:1904424	regulation of GTP binding	3/988	15/18722	0.0414385978956401	0.124362616961379	ARHGAP28/CSNK1A1/ARHGEF7	3
GO:2000402	negative regulation of lymphocyte migration	3/988	15/18722	0.0414385978956401	0.124362616961379	CD200/LRCH1/WASL	3
GO:2001028	positive regulation of endothelial cell chemotaxis	3/988	15/18722	0.0414385978956401	0.124362616961379	KDR/FGFR1/TMSB4X	3
GO:0009314	response to radiation	33/988	456/18722	0.0415427258093529	0.124604720214163	COL3A1/HYAL2/TANC1/THBD/ANGPT2/IFI16/ITGB1/RHOB/TIMP1/CARD16/APP/GNAQ/DUSP1/PML/TP53INP1/HIF1A/POLK/CREB1/NPTN/EGR1/CLOCK/CCND1/F11R/TRIM13/PRKAA1/NIPBL/ID2/PIAS1/NEDD4/JUN/IKBIP/ZMPSTE24/BHLHE40	33
GO:0035966	response to topologically incorrect protein	14/988	159/18722	0.0419445936202369	0.125668178968245	THBS1/CLU/TRAM1/SERPINH1/ATXN3/ERO1A/TMBIM6/EIF2AK2/EDEM3/CCND1/ATF6/CREBRF/HSPA1A/HSPH1	14
GO:1903169	regulation of calcium ion transmembrane transport	14/988	159/18722	0.0419445936202369	0.125668178968245	APLNR/RAMP3/F2R/PDE4D/CLIC2/FKBP1A/PRKCE/CALM1/FYN/SESTD1/STIM2/PDE4B/AHNAK/PKD2	14
GO:0031110	regulation of microtubule polymerization or depolymerization	9/988	88/18722	0.0422771143431423	0.126593027841472	CDH5/GIT1/TAOK1/APC/ARHGEF7/DYRK1A/HSPA1A/CAMSAP2/NIN	9
GO:0030518	intracellular steroid hormone receptor signaling pathway	11/988	116/18722	0.0426996764022864	0.127714347437469	PLPP1/FOXP1/DDX17/PKN1/RHOA/ZMIZ1/CLOCK/NR3C1/CNOT2/NEDD4/ARID1A	11
GO:0051283	negative regulation of sequestering of calcium ion	11/988	116/18722	0.0426996764022864	0.127714347437469	APLNR/F2R/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/ERO1A/ITPR2/PKD2	11
GO:1904063	negative regulation of cation transmembrane transport	10/988	102/18722	0.0428198658659571	0.12800175997747	CAV1/CLIC2/PRKCE/CALM1/SESTD1/PTEN/SLC30A1/PKD2/CRBN/NEDD4	10
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	6/988	49/18722	0.0430626589563685	0.128287176859216	ACVRL1/ENG/BMPR2/TGFB1/SDCBP/SMAD4	6
GO:0030225	macrophage differentiation	6/988	49/18722	0.0430626589563685	0.128287176859216	APP/RB1/TGFB1/GATA2/CDC42/ID2	6
GO:0032692	negative regulation of interleukin-1 production	6/988	49/18722	0.0430626589563685	0.128287176859216	IGF1/CEACAM1/GIT1/CARD16/PML/CARD8	6
GO:0045778	positive regulation of ossification	6/988	49/18722	0.0430626589563685	0.128287176859216	KL/MEF2C/BMPR2/TGFB1/ISG15/NIPBL	6
GO:0052372	modulation by symbiont of entry into host	6/988	49/18722	0.0430626589563685	0.128287176859216	CAV1/IFITM2/IFITM3/IFITM1/LGALS1/GSN	6
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	6/988	49/18722	0.0430626589563685	0.128287176859216	EDN1/IGF1/PDGFB/GNAI2/GJA1/JUN	6
GO:0002699	positive regulation of immune effector process	19/988	235/18722	0.0430843982524175	0.128287176859216	HLX/FOXF1/IL1R1/HLA-E/HLA-A/HLA-B/B2M/CD81/DDX60/TGFB1/LAMP1/TNFRSF14/CD36/GATA2/CD46/KMT5B/RIF1/BCL10/RAP1A	19
GO:0043524	negative regulation of neuron apoptotic process	13/988	145/18722	0.0431956023916417	0.128546240842801	NDNF/F2R/MEF2C/ANGPT1/NRP1/HIPK2/MDK/FYN/PIK3CA/RHOA/HIF1A/GBE1/BTG2	13
GO:0002369	T cell cytokine production	5/988	37/18722	0.0435499087742398	0.12916645193119	IL1R1/HLA-A/B2M/CD81/TNFRSF1B	5
GO:0002724	regulation of T cell cytokine production	5/988	37/18722	0.0435499087742398	0.12916645193119	IL1R1/HLA-A/B2M/CD81/TNFRSF1B	5
GO:0016202	regulation of striated muscle tissue development	5/988	37/18722	0.0435499087742398	0.12916645193119	MEF2C/IGF2/TGFB1/CREB1/PRKAA1	5
GO:0032570	response to progesterone	5/988	37/18722	0.0435499087742398	0.12916645193119	RAMP2/CAV1/TXNIP/THBS1/TGFB1	5
GO:0034260	negative regulation of GTPase activity	5/988	37/18722	0.0435499087742398	0.12916645193119	RASA4/RDX/LRCH1/F11R/WNK1	5
GO:0060416	response to growth hormone	5/988	37/18722	0.0435499087742398	0.12916645193119	PXN/LEPROTL1/STAT3/LEPROT/PTK2	5
GO:0008088	axo-dendritic transport	8/988	75/18722	0.0436232364760581	0.129167576455307	DST/KIF5B/APP/ARMCX3/HIF1A/PURA/KIF1B/DYNC1H1	8
GO:0036465	synaptic vesicle recycling	8/988	75/18722	0.0436232364760581	0.129167576455307	SYT11/CANX/CALM1/ITSN2/KIAA1109/PICALM/ROCK1/RAB5A	8
GO:0043627	response to estrogen	8/988	75/18722	0.0436232364760581	0.129167576455307	CRHBP/TEK/SMAD6/CAV1/TGFBR2/CTNNA1/CCND1/MAPK1	8
GO:0034765	regulation of ion transmembrane transport	35/988	491/18722	0.0440340062032065	0.130086525480817	APLNR/CRHBP/RAMP3/F2R/MEF2C/CAV1/PDE4D/CLIC2/FKBP1A/PRKCE/ITGB1/TMSB4X/UTRN/KIF5B/STOM/ACTN4/APP/CALM1/FYN/SESTD1/STIM2/PTEN/PDE4B/FLNA/AHNAK/SLC30A1/PKD2/FXYD5/CLIC4/ATP2B4/CRBN/GJA5/WNK1/NEDD4/ZMPSTE24	35
GO:0007062	sister chromatid cohesion	7/988	62/18722	0.0441050136278146	0.130086525480817	RB1/ATRX/PDS5B/SLF2/POGZ/STAG2/NIPBL	7
GO:0048488	synaptic vesicle endocytosis	7/988	62/18722	0.0441050136278146	0.130086525480817	SYT11/CANX/CALM1/ITSN2/KIAA1109/PICALM/ROCK1	7
GO:0060135	maternal process involved in female pregnancy	7/988	62/18722	0.0441050136278146	0.130086525480817	BMPR2/ANGPT2/PAM/GJA1/NR2F2/ASH1L/MAPK1	7
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	7/988	62/18722	0.0441050136278146	0.130086525480817	ACVRL1/SMAD6/ENG/BMPR2/TGFB1/SDCBP/SMAD4	7
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	7/988	62/18722	0.0441050136278146	0.130086525480817	CTNND1/STX3/AP2B1/ADAM10/PPP3R1/RAB11A/RAP1A	7
GO:0140238	presynaptic endocytosis	7/988	62/18722	0.0441050136278146	0.130086525480817	SYT11/CANX/CALM1/ITSN2/KIAA1109/PICALM/ROCK1	7
GO:0031647	regulation of protein stability	23/988	298/18722	0.0441930811059978	0.130273943859634	IGF1/TMEM88/HIP1/CLU/CD81/GNAQ/CTNND1/PLPP3/LAMP1/PTEN/SEL1L/FLNA/CREB1/RTN4/ATF7IP/GSN/SH3GLB1/B4GALT5/CRTAP/HSPA1A/MAPK1/GOLGA7/SAV1	23
GO:0018022	peptidyl-lysine methylation	12/988	131/18722	0.0442426299551192	0.13034767072745	NNMT/MECOM/BCOR/KMT2E/ATRX/KMT2A/OGT/ASH1L/WDR82/KMT5B/RIF1/SMAD4	12
GO:0002702	positive regulation of production of molecular mediator of immune response	11/988	117/18722	0.0449857715411039	0.132463646577796	IL1R1/HLA-E/HLA-A/B2M/CD81/TGFB1/TNFRSF14/CD36/KMT5B/RIF1/BCL10	11
GO:0044262	cellular carbohydrate metabolic process	22/988	283/18722	0.0451948110040368	0.133005449337088	IGFBP4/IGF1/NNMT/LEPR/P2RY1/PCDH12/PRKCE/IGF2/GIT1/PDK4/SCARB2/IL6ST/PTEN/RANBP2/OGT/ARPP19/STAT3/RB1CC1/MIDN/GBE1/B4GALT5/ZMPSTE24	22
GO:0014013	regulation of gliogenesis	10/988	103/18722	0.0452831286667163	0.133191572246731	NOTCH1/MDK/DICER1/PRKCH/IL6ST/TGFB1/SKI/TNFRSF1B/HES1/ID2	10
GO:0002418	immune response to tumor cell	4/988	26/18722	0.0456690909782192	0.133440160217987	CEACAM1/ADAM15/HLA-A/AHR	4
GO:0006027	glycosaminoglycan catabolic process	4/988	26/18722	0.0456690909782192	0.133440160217987	HYAL2/TGFB1/GNS/CD44	4
GO:0014829	vascular associated smooth muscle contraction	4/988	26/18722	0.0456690909782192	0.133440160217987	EDN1/DOCK4/RHOA/PIK3C2A	4
GO:0032515	negative regulation of phosphoprotein phosphatase activity	4/988	26/18722	0.0456690909782192	0.133440160217987	FKBP1A/GNAI2/ROCK2/ROCK1	4
GO:0033598	mammary gland epithelial cell proliferation	4/988	26/18722	0.0456690909782192	0.133440160217987	RTN4/CCND1/MAPK1/ID2	4
GO:0060544	regulation of necroptotic process	4/988	26/18722	0.0456690909782192	0.133440160217987	CAV1/CFLAR/OGT/CYLD	4
GO:0060669	embryonic placenta morphogenesis	4/988	26/18722	0.0456690909782192	0.133440160217987	RSPO3/IGF2/ZFP36L1/SOCS3	4
GO:0070102	interleukin-6-mediated signaling pathway	4/988	26/18722	0.0456690909782192	0.133440160217987	JAK1/IL6ST/STAT3/SMAD4	4
GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	4/988	26/18722	0.0456690909782192	0.133440160217987	TGFB1/STAT3/PPP3CA/ZMPSTE24	4
GO:0071425	hematopoietic stem cell proliferation	4/988	26/18722	0.0456690909782192	0.133440160217987	CD34/MECOM/N4BP2L2/EIF2AK2	4
GO:1904376	negative regulation of protein localization to cell periphery	4/988	26/18722	0.0456690909782192	0.133440160217987	PPP2R5A/TGFB1/PICALM/HECTD1	4
GO:1905523	positive regulation of macrophage migration	4/988	26/18722	0.0456690909782192	0.133440160217987	THBS1/MDK/PTK2/MAPK1	4
GO:0002768	immune response-regulating cell surface receptor signaling pathway	24/988	315/18722	0.0458710564196991	0.133956597966708	FCGR2B/CEACAM1/MEF2C/PDE4D/FOXP1/PRKCE/HLA-A/CD81/YES1/PRKCH/FYN/PIK3CA/PDE4B/CMTM3/PLSCR1/RC3H1/PAK2/CBLB/WNK1/PTK2/SOS1/MAPK1/BCL10/RAP1A	24
GO:0072175	epithelial tube formation	12/988	132/18722	0.0464377918047704	0.135537115421396	PODXL/DLC1/TGFB1/LUZP1/MIB1/HIF1A/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	12
GO:0014823	response to activity	8/988	76/18722	0.0466008480676348	0.135714750512761	EDN1/ITGA2/COL4A2/ANGPT2/PTEN/HIF1A/CREB1/PRKAA1	8
GO:0031100	animal organ regeneration	8/988	76/18722	0.0466008480676348	0.135714750512761	NNMT/ANGPT2/NOTCH1/TGFBR2/SULF2/CPT1A/CCND1/RAP1A	8
GO:0045685	regulation of glial cell differentiation	8/988	76/18722	0.0466008480676348	0.135714750512761	NOTCH1/MDK/DICER1/IL6ST/TGFB1/TNFRSF1B/HES1/ID2	8
GO:2000379	positive regulation of reactive oxygen species metabolic process	8/988	76/18722	0.0466008480676348	0.135714750512761	THBS1/TGFBR2/PDGFB/GNAI2/TGFB1/CD36/RAB27A/CLCN3	8
GO:0001961	positive regulation of cytokine-mediated signaling pathway	6/988	50/18722	0.0468418476707787	0.136192608006117	EDN1/IL1R1/PARP14/HIF1A/PARP9/HSPA1A	6
GO:0018023	peptidyl-lysine trimethylation	6/988	50/18722	0.0468418476707787	0.136192608006117	KMT2E/ATRX/KMT2A/OGT/WDR82/KMT5B	6
GO:2000677	regulation of transcription regulatory region DNA binding	6/988	50/18722	0.0468418476707787	0.136192608006117	IGF1/TMSB4X/RB1/TGFB1/KLF4/ZMPSTE24	6
GO:0051282	regulation of sequestering of calcium ion	11/988	118/18722	0.0473542517042234	0.137607103420588	APLNR/F2R/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/ERO1A/ITPR2/PKD2	11
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	7/988	63/18722	0.0474571985669702	0.137680305181729	ITPR1/SERINC3/DNAJC10/PML/ERO1A/TMBIM6/HSPA1A	7
GO:2000242	negative regulation of reproductive process	7/988	63/18722	0.0474571985669702	0.137680305181729	IGF1/RPS6KA2/TIMP1/DUSP1/GJA1/PRKAR1A/MYH9	7
GO:2000756	regulation of peptidyl-lysine acetylation	7/988	63/18722	0.0474571985669702	0.137680305181729	KMT2A/GATA2/EID1/PRKAA1/DIP2A/SMAD4/ZMPSTE24	7
GO:0002028	regulation of sodium ion transport	9/988	90/18722	0.0476910796416791	0.138057228913678	PRKCE/UTRN/KIF5B/STOM/ACTN4/FXYD5/ATP2B4/WNK1/NEDD4	9
GO:0046031	ADP metabolic process	9/988	90/18722	0.0476910796416791	0.138057228913678	IGF1/NT5E/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	9
GO:0099175	regulation of postsynapse organization	9/988	90/18722	0.0476910796416791	0.138057228913678	FCGR2B/SRGN/PDLIM5/FYN/PTEN/ACTR2/ABI2/ADAM10/SEMA3F	9
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	9/988	90/18722	0.0476910796416791	0.138057228913678	EDN1/IGF1/MEF2C/PDGFB/GNAI2/GJA1/PTEN/RHOA/JUN	9
GO:0046634	regulation of alpha-beta T cell activation	10/988	104/18722	0.0478404598098199	0.138414227946494	HLX/HLA-E/HLA-A/TGFBR2/CD81/TNFRSF14/RHOA/RC3H1/CBLB/HSPH1	10
GO:0001825	blastocyst formation	5/988	38/18722	0.0480563994128858	0.1385860986326	SKIL/MFNG/GABPA/RTN4/CNOT2	5
GO:0002478	antigen processing and presentation of exogenous peptide antigen	5/988	38/18722	0.0480563994128858	0.1385860986326	FCGR2B/HLA-E/HLA-A/B2M/LNPEP	5
GO:0046329	negative regulation of JNK cascade	5/988	38/18722	0.0480563994128858	0.1385860986326	MECOM/AIDA/ZMYND11/CYLD/HIPK3	5
GO:0048246	macrophage chemotaxis	5/988	38/18722	0.0480563994128858	0.1385860986326	MTUS1/THBS1/MDK/PTK2/MAPK1	5
GO:0071398	cellular response to fatty acid	5/988	38/18722	0.0480563994128858	0.1385860986326	EDN1/ID3/PDK4/CPT1A/CREB1	5
GO:1903725	regulation of phospholipid metabolic process	5/988	38/18722	0.0480563994128858	0.1385860986326	ADGRF5/SCARB1/PDGFB/ACSL3/CAPN2	5
GO:0003084	positive regulation of systemic arterial blood pressure	3/988	16/18722	0.049057026478974	0.140404593026029	RHOA/NR2F2/WNK1	3
GO:0009299	mRNA transcription	3/988	16/18722	0.049057026478974	0.140404593026029	FLNA/STAT3/HIPK3	3
GO:0021535	cell migration in hindbrain	3/988	16/18722	0.049057026478974	0.140404593026029	ITGB1/PLXNA2/FLNA	3
GO:0021783	preganglionic parasympathetic fiber development	3/988	16/18722	0.049057026478974	0.140404593026029	NRP1/SEMA3F/HES1	3
GO:0030575	nuclear body organization	3/988	16/18722	0.049057026478974	0.140404593026029	ETS1/HIPK2/PML	3
GO:0031268	pseudopodium organization	3/988	16/18722	0.049057026478974	0.140404593026029	CDC42EP5/APC/CDC42	3
GO:0032274	gonadotropin secretion	3/988	16/18722	0.049057026478974	0.140404593026029	GJA1/TBX3/SMAD4	3
GO:0035970	peptidyl-threonine dephosphorylation	3/988	16/18722	0.049057026478974	0.140404593026029	PPM1F/DUSP1/PPP2CB	3
GO:0044849	estrous cycle	3/988	16/18722	0.049057026478974	0.140404593026029	ETS1/MDK/EGR1	3
GO:0045651	positive regulation of macrophage differentiation	3/988	16/18722	0.049057026478974	0.140404593026029	RB1/TGFB1/ID2	3
GO:0051014	actin filament severing	3/988	16/18722	0.049057026478974	0.140404593026029	MYH9/GSN/DSTN	3
GO:0071732	cellular response to nitric oxide	3/988	16/18722	0.049057026478974	0.140404593026029	FOXO1/CFLAR/CRK	3
GO:1901163	regulation of trophoblast cell migration	3/988	16/18722	0.049057026478974	0.140404593026029	TIMP1/SMURF2/GJA1	3
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	3/988	16/18722	0.049057026478974	0.140404593026029	KIF5B/ACTN4/WNK1	3
GO:0010827	regulation of glucose transmembrane transport	8/988	77/18722	0.049708161727507	0.142038598760902	EDN1/IGF1/FABP5/MEF2A/PEA15/YES1/ARPP19/RAP1A	8
GO:0048644	muscle organ morphogenesis	8/988	77/18722	0.049708161727507	0.142038598760902	HEG1/S1PR1/TCF15/ENG/FKBP1A/NOTCH1/TGFB1/SMAD4	8
GO:1901983	regulation of protein acetylation	8/988	77/18722	0.049708161727507	0.142038598760902	TAOK1/KMT2A/GATA2/EID1/PRKAA1/DIP2A/SMAD4/ZMPSTE24	8
GO:0010906	regulation of glucose metabolic process	11/988	119/18722	0.049806136593856	0.142242041713206	IGFBP4/IGF1/NNMT/LEPR/IGF2/PDK4/RANBP2/OGT/ARPP19/MIDN/ZMPSTE24	11
GO:0072331	signal transduction by p53 class mediator	14/988	163/18722	0.0498694154210152	0.142346230368851	NUAK1/IFI16/HIPK2/PML/ATRX/NDRG1/HIPK1/CD44/SP100/KAT6A/DYRK1A/HNRNPK/PLK2/ZMPSTE24	14
GO:1990874	vascular associated smooth muscle cell proliferation	9/988	91/18722	0.050562640645435	0.144247447426719	EDN1/IGF1/MEF2C/PDGFB/GNAI2/GJA1/PTEN/RHOA/JUN	9
GO:0010656	negative regulation of muscle cell apoptotic process	6/988	51/18722	0.0508201067609147	0.144857733094015	EDN1/IGF1/LRP6/MDK/CFLAR/RGL2	6
GO:0030888	regulation of B cell proliferation	7/988	64/18722	0.0509674516477247	0.144857733094015	FCGR2B/MEF2C/AHR/CD81/PKN1/RC3H1/CD320	7
GO:0046854	phosphatidylinositol phosphate biosynthetic process	7/988	64/18722	0.0509674516477247	0.144857733094015	PIK3R3/SOCS3/PIK3CA/PIK3C2B/PIK3C2A/SOCS4/SMG1	7
GO:0046888	negative regulation of hormone secretion	7/988	64/18722	0.0509674516477247	0.144857733094015	EDN1/CRHBP/GJA1/MAP4K4/PPP3CA/PIM3/MIDN	7
GO:0048857	neural nucleus development	7/988	64/18722	0.0509674516477247	0.144857733094015	NFIB/CALM1/GNB4/RHOA/ZNF148/ATF2/CDC42	7
GO:0070542	response to fatty acid	7/988	64/18722	0.0509674516477247	0.144857733094015	EDN1/FOXO1/ID3/PDK4/CPT1A/CD36/CREB1	7
GO:1903409	reactive oxygen species biosynthetic process	7/988	64/18722	0.0509674516477247	0.144857733094015	CFLAR/FYN/CD36/RAB27A/RHOA/STAT3/CLCN3	7
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	4/988	27/18722	0.0514547368074582	0.145852487684748	APP/CDC25B/CCND1/RAB11A	4
GO:0018126	protein hydroxylation	4/988	27/18722	0.0514547368074582	0.145852487684748	PLOD2/ERO1A/EGLN1/CRTAP	4
GO:0031954	positive regulation of protein autophosphorylation	4/988	27/18722	0.0514547368074582	0.145852487684748	VEGFC/PDGFB/CALM1/IQGAP1	4
GO:0034453	microtubule anchoring	4/988	27/18722	0.0514547368074582	0.145852487684748	BICD1/CCDC68/PCM1/NIN	4
GO:0060333	interferon-gamma-mediated signaling pathway	4/988	27/18722	0.0514547368074582	0.145852487684748	JAK1/PARP14/PARP9/SP100	4
GO:0007626	locomotory behavior	15/988	179/18722	0.0519313728288559	0.147125041315671	PREX2/FZD4/PRKCE/RCAN1/GIT1/HIPK2/APP/PTEN/EGR1/CRBN/UBA6/STRN/CLCN3/ID2/ZMPSTE24	15
GO:1903522	regulation of blood circulation	20/988	256/18722	0.0519934811702678	0.14722247973159	EDN1/ECE1/F2R/CAV1/BMPR2/PDE4D/CLIC2/EPAS1/THRA/DOCK4/MEF2A/ADRB1/CALM1/GJA1/PDE4B/FLNA/RHOA/ATP2B4/GJA5/ZMPSTE24	20
GO:0002761	regulation of myeloid leukocyte differentiation	11/988	120/18722	0.0523423822742138	0.1481314515933	CEACAM1/FOXP1/ZFP36L1/RB1/CDK6/TGFB1/CREB1/GATA2/KLF10/ID2/JUN	11
GO:0002701	negative regulation of production of molecular mediator of immune response	5/988	39/18722	0.052828077051818	0.149346857530206	FCGR2B/BST2/ANGPT1/TGFB1/TMBIM6	5
GO:1901861	regulation of muscle tissue development	5/988	39/18722	0.052828077051818	0.149346857530206	MEF2C/IGF2/TGFB1/CREB1/PRKAA1	5
GO:0034599	cellular response to oxidative stress	22/988	288/18722	0.0528669817012565	0.149377344040997	FOXO1/EPAS1/ETS1/KLF2/RHOB/PCGF2/PXN/PML/FYN/TP53INP1/KLF4/NCOA7/SETX/CD36/HIF1A/PKD2/PRKAA1/ATF2/HSPA1A/MAPK1/JUN/NFE2L1	22
GO:0009150	purine ribonucleotide metabolic process	27/988	368/18722	0.0528999341599859	0.149390988972804	IGF1/PAPSS2/NT5E/ADCY4/ZBTB20/NPR1/PDE4D/GIMAP7/TMSB4X/GIT1/PDK4/APP/TGFB1/NUDT3/ACSL3/PDE4B/ELOVL5/RHOA/HIF1A/HSD17B12/OGT/STAT3/ATP6V1A/ACAT1/PRKAA1/DIP2A/FAR1	27
GO:0090559	regulation of membrane permeability	8/988	78/18722	0.0529465508603471	0.149443187125486	HEG1/RASIP1/JAM3/STAT3/F11R/PDCD6IP/ATF2/HSPA1A	8
GO:0006906	vesicle fusion	10/988	106/18722	0.0532418108562279	0.150196760099991	STXBP6/CAV2/SYT11/KIF5B/STX3/TBC1D4/SAMD9/DYSF/SNAP23/YIPF4	10
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	21/988	273/18722	0.0541915513361431	0.152794862366025	SPARCL1/PECAM1/CDH5/CLDN5/ESAM/ROBO4/SELP/HMCN1/CLDN11/CEACAM1/PCDH12/DCHS1/TGFBR2/ITGB1/KLF4/PALLD/PTPRM/NPTN/FXYD5/WNK1/KIFAP3	21
GO:0015909	long-chain fatty acid transport	7/988	65/18722	0.0546371797086692	0.153887963209147	FABP4/FABP5/THBS1/CPT1A/ACSL3/CD36/SLC2A1	7
GO:0071677	positive regulation of mononuclear cell migration	7/988	65/18722	0.0546371797086692	0.153887963209147	JAM2/APP/TNFRSF14/RHOA/ADAM10/MOSPD2/WNK1	7
GO:0001838	embryonic epithelial tube formation	11/988	121/18722	0.0549638792852668	0.154578654670646	DLC1/TGFB1/LUZP1/MIB1/HIF1A/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	11
GO:0042752	regulation of circadian rhythm	11/988	121/18722	0.0549638792852668	0.154578654670646	ADRB1/GNAQ/PML/CREB1/CLOCK/PRKAA1/NR1D2/KLF10/ROCK2/ID2/BHLHE40	11
GO:0043392	negative regulation of DNA binding	6/988	52/18722	0.0549988059728012	0.154578654670646	ID1/IFI16/TMSB4X/RSF1/SP100/JUN	6
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	6/988	52/18722	0.0549988059728012	0.154578654670646	RSPO3/SMURF2/RHOA/FZD6/DAAM1/CDC42	6
GO:0006006	glucose metabolic process	16/988	196/18722	0.0556355966345659	0.156285716193979	IGFBP4/IGF1/NNMT/LEPR/FABP5/IGF2/PDK4/CPT1A/PIK3CA/KBTBD2/RANBP2/OGT/ARPP19/PRKAA1/MIDN/ZMPSTE24	16
GO:0005976	polysaccharide metabolic process	10/988	107/18722	0.056087855333361	0.157223581810456	IGF1/LEPR/PCDH12/IGF2/PDGFB/IL6ST/TGFB1/RB1CC1/GBE1/B4GALT5	10
GO:0006275	regulation of DNA replication	10/988	107/18722	0.056087855333361	0.157223581810456	ACVRL1/DACH1/ID3/ATRX/ZBTB38/TNFAIP1/CCDC88A/CDC42/JUN/ZMPSTE24	10
GO:0071868	cellular response to monoamine stimulus	10/988	107/18722	0.056087855333361	0.157223581810456	CAV2/ID1/APP/GNB1/GABPA/PDE4B/FLNA/ARPP19/ATP2B4/MAPK1	10
GO:0071870	cellular response to catecholamine stimulus	10/988	107/18722	0.056087855333361	0.157223581810456	CAV2/ID1/APP/GNB1/GABPA/PDE4B/FLNA/ARPP19/ATP2B4/MAPK1	10
GO:0032640	tumor necrosis factor production	15/988	181/18722	0.0561691049217358	0.157285337556279	CD34/IGF1/IL33/FOXP1/SYT11/HLA-E/THBS1/ANGPT1/CLU/APP/DICER1/OAS2/CD36/ZFP36/STAT3	15
GO:0032680	regulation of tumor necrosis factor production	15/988	181/18722	0.0561691049217358	0.157285337556279	CD34/IGF1/IL33/FOXP1/SYT11/HLA-E/THBS1/ANGPT1/CLU/APP/DICER1/OAS2/CD36/ZFP36/STAT3	15
GO:0051279	regulation of release of sequestered calcium ion into cytosol	8/988	79/18722	0.0563172132039431	0.157616984478054	APLNR/F2R/PDE4D/CLIC2/FKBP1A/PRKCE/CALM1/PKD2	8
GO:0030902	hindbrain development	13/988	151/18722	0.0564193799572996	0.157736708596408	FCGR2B/NFIB/FZD4/DLC1/ITGB1/SMAD1/MDK/PLXNA2/FLNA/GATA2/CRK/ATF2/HES1	13
GO:0048592	eye morphogenesis	13/988	151/18722	0.0564193799572996	0.157736708596408	JAG1/TSPAN12/HIPK2/TUG1/ABI2/HIF1A/SKI/PTPRM/PHACTR4/STAT3/HIPK1/EFEMP1/NIPBL	13
GO:0001780	neutrophil homeostasis	3/988	17/18722	0.0573053301813924	0.159041752311158	SH2B3/JAM3/PDE4B	3
GO:0010612	regulation of cardiac muscle adaptation	3/988	17/18722	0.0573053301813924	0.159041752311158	FOXO1/ATP2B4/PPP3CA	3
GO:0010715	regulation of extracellular matrix disassembly	3/988	17/18722	0.0573053301813924	0.159041752311158	FSCN1/ETS1/TGFB1	3
GO:0014856	skeletal muscle cell proliferation	3/988	17/18722	0.0573053301813924	0.159041752311158	ANGPT1/CFLAR/STAT3	3
GO:0038065	collagen-activated signaling pathway	3/988	17/18722	0.0573053301813924	0.159041752311158	ITGA2/COL4A1/COL4A2	3
GO:0043117	positive regulation of vascular permeability	3/988	17/18722	0.0573053301813924	0.159041752311158	TJP1/ANGPT1/TGFB1	3
GO:0060644	mammary gland epithelial cell differentiation	3/988	17/18722	0.0573053301813924	0.159041752311158	FOXF1/HIF1A/ID2	3
GO:0061450	trophoblast cell migration	3/988	17/18722	0.0573053301813924	0.159041752311158	TIMP1/SMURF2/GJA1	3
GO:0070293	renal absorption	3/988	17/18722	0.0573053301813924	0.159041752311158	HYAL2/GSN/MAGED2	3
GO:0070593	dendrite self-avoidance	3/988	17/18722	0.0573053301813924	0.159041752311158	ROBO4/PALLD/NPTN	3
GO:0072673	lamellipodium morphogenesis	3/988	17/18722	0.0573053301813924	0.159041752311158	ENPP2/CD44/ARHGEF7	3
GO:0090713	immunological memory process	3/988	17/18722	0.0573053301813924	0.159041752311158	CD81/TNFRSF14/CD46	3
GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	3/988	17/18722	0.0573053301813924	0.159041752311158	NFIB/PDGFB/TGFB1	3
GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	3/988	17/18722	0.0573053301813924	0.159041752311158	FOXO1/ATP2B4/PPP3CA	3
GO:0002313	mature B cell differentiation involved in immune response	4/988	28/18722	0.0576209989065147	0.159252209256715	FCGR2B/ITM2A/MFNG/LGALS1	4
GO:0002507	tolerance induction	4/988	28/18722	0.0576209989065147	0.159252209256715	HLA-E/HLA-B/TGFBR2/CBLB	4
GO:0010575	positive regulation of vascular endothelial growth factor production	4/988	28/18722	0.0576209989065147	0.159252209256715	SULF2/IL6ST/TGFB1/HIF1A	4
GO:0010818	T cell chemotaxis	4/988	28/18722	0.0576209989065147	0.159252209256715	SLC12A2/ADAM10/PLEC/WNK1	4
GO:0032801	receptor catabolic process	4/988	28/18722	0.0576209989065147	0.159252209256715	TGFB1/DTX3L/SH3GLB1/NEDD4	4
GO:0034123	positive regulation of toll-like receptor signaling pathway	4/988	28/18722	0.0576209989065147	0.159252209256715	CAV1/RTN4/WDFY1/PJA2	4
GO:1902624	positive regulation of neutrophil migration	4/988	28/18722	0.0576209989065147	0.159252209256715	EDN1/IL1R1/MDK/MOSPD2	4
GO:1990776	response to angiotensin	4/988	28/18722	0.0576209989065147	0.159252209256715	CAV1/IQGAP1/ROCK2/ROCK1	4
GO:0030501	positive regulation of bone mineralization	5/988	40/18722	0.0578653364001255	0.159512541233766	KL/MEF2C/BMPR2/TGFB1/ISG15	5
GO:0043001	Golgi to plasma membrane protein transport	5/988	40/18722	0.0578653364001255	0.159512541233766	SPTBN1/MACF1/VAMP5/ACSL3/GOLGA7	5
GO:0071526	semaphorin-plexin signaling pathway	5/988	40/18722	0.0578653364001255	0.159512541233766	PLXND1/NRP1/PLXNA2/FLNA/SEMA3F	5
GO:0150077	regulation of neuroinflammatory response	5/988	40/18722	0.0578653364001255	0.159512541233766	IGF1/IL33/SYT11/CD200/TNFRSF1B	5
GO:1901223	negative regulation of NIK/NF-kappaB signaling	5/988	40/18722	0.0578653364001255	0.159512541233766	UACA/HDAC7/TMSB4X/TSPAN6/CYLD	5
GO:0006986	response to unfolded protein	12/988	137/18722	0.0585378468783568	0.161199088967253	THBS1/TRAM1/SERPINH1/ERO1A/TMBIM6/EIF2AK2/EDEM3/CCND1/ATF6/CREBRF/HSPA1A/HSPH1	12
GO:0050671	positive regulation of lymphocyte proliferation	12/988	137/18722	0.0585378468783568	0.161199088967253	IGF1/MEF2C/HLA-E/HLA-A/TGFBR2/IGF2/CD81/EFNB1/IL6ST/CD320/CD46/HES1	12
GO:0006260	DNA replication	20/988	260/18722	0.0591307042492998	0.162747306203254	NFIB/ACVRL1/NFIA/DACH1/ID3/REV3L/RBMS1/ATRX/NFIC/ZBTB38/POLK/PURA/RECQL/TNFAIP1/FAM111A/CCDC88A/PTMS/CDC42/JUN/ZMPSTE24	20
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	26/988	356/18722	0.0591693672664306	0.162769383179326	FCGR2B/CFI/HLX/CEACAM1/MEF2C/JAG1/IL1R1/HLA-E/HLA-A/AHR/HLA-B/NOTCH1/CLU/B2M/CD81/PKN1/TGFB1/RAB27A/STAT3/RC3H1/EMP2/TNFRSF1B/CD46/KMT5B/RIF1/BCL10	26
GO:0043113	receptor clustering	6/988	53/18722	0.059378875542041	0.163176713336431	AGRN/CD81/FLNA/GSN/SYNJ2BP/SAV1	6
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	6/988	53/18722	0.059378875542041	0.163176713336431	APLNR/BICD1/GNAI2/PDE4B/ATP2B4/YWHAB	6
GO:0007422	peripheral nervous system development	8/988	80/18722	0.0598211681505568	0.164215184610537	LAMA2/ADGRG6/LAMB2/DICER1/SKI/NDRG1/PPP3R1/PLEC	8
GO:0021766	hippocampus development	8/988	80/18722	0.0598211681505568	0.164215184610537	KIF5B/CDK6/MDK/PTEN/ATP2B4/CRK/UBA6/BTG2	8
GO:0002690	positive regulation of leukocyte chemotaxis	9/988	94/18722	0.0598495100538404	0.164215184610537	EDN1/VEGFC/THBS1/MDK/ADAM10/MOSPD2/WNK1/PTK2/MAPK1	9
GO:0032946	positive regulation of mononuclear cell proliferation	12/988	138/18722	0.0611881149064187	0.167628296226352	IGF1/MEF2C/HLA-E/HLA-A/TGFBR2/IGF2/CD81/EFNB1/IL6ST/CD320/CD46/HES1	12
GO:0035107	appendage morphogenesis	12/988	138/18722	0.0611881149064187	0.167628296226352	ECE1/HOXA13/PCSK5/NOTCH1/MBNL1/ATRX/PLXNA2/SKI/TBX3/FZD6/NIPBL/SMAD4	12
GO:0035108	limb morphogenesis	12/988	138/18722	0.0611881149064187	0.167628296226352	ECE1/HOXA13/PCSK5/NOTCH1/MBNL1/ATRX/PLXNA2/SKI/TBX3/FZD6/NIPBL/SMAD4	12
GO:0016197	endosomal transport	18/988	230/18722	0.0619142530997722	0.169530161064943	EHD2/ANKRD50/TMCC1/LEPROTL1/ITSN2/LYST/TMEM50B/ACAP2/KIAA1109/ABCA1/EHD4/PICALM/SPAG9/LEPROT/RAB11A/TMEM50A/TMEM87B/VPS36	18
GO:0034766	negative regulation of ion transmembrane transport	10/988	109/18722	0.0620750693616527	0.169882930679598	CAV1/CLIC2/PRKCE/CALM1/SESTD1/PTEN/SLC30A1/PKD2/CRBN/NEDD4	10
GO:0046635	positive regulation of alpha-beta T cell activation	7/988	67/18722	0.0624593407553877	0.170846559264994	HLX/HLA-E/HLA-A/TGFBR2/CD81/RHOA/HSPH1	7
GO:0007051	spindle organization	15/988	184/18722	0.0629610548803109	0.171958643504313	ATRX/MYH9/CCDC69/FLNA/RHOA/TACC1/STAG2/NEK7/MAP4/RAB11A/DYNC1H1/HSPA1A/PLK2/CHD3/SENP6	15
GO:0031062	positive regulation of histone methylation	5/988	41/18722	0.063167793501179	0.171958643504313	KMT2E/KMT2A/OGT/RIF1/SMAD4	5
GO:0048634	regulation of muscle organ development	5/988	41/18722	0.063167793501179	0.171958643504313	MEF2C/IGF2/TGFB1/CREB1/PRKAA1	5
GO:0050856	regulation of T cell receptor signaling pathway	5/988	41/18722	0.063167793501179	0.171958643504313	CEACAM1/CD81/RC3H1/CBLB/BCL10	5
GO:0055023	positive regulation of cardiac muscle tissue growth	5/988	41/18722	0.063167793501179	0.171958643504313	EDN1/IGF1/MEF2C/NOTCH1/MAPK1	5
GO:1902622	regulation of neutrophil migration	5/988	41/18722	0.063167793501179	0.171958643504313	EDN1/IL1R1/MDK/JAM3/MOSPD2	5
GO:0045666	positive regulation of neuron differentiation	9/988	95/18722	0.063172328151638	0.171958643504313	TCF4/ZEB1/MEF2C/FGFR1/PTEN/RHOA/TCF12/GATA2/SPAG9	9
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	9/988	95/18722	0.063172328151638	0.171958643504313	NXN/CAV1/PRKCE/FYN/ISG15/OGT/DTX3L/TRIP12/HSPA1A	9
GO:0031349	positive regulation of defense response	21/988	278/18722	0.0631733290306081	0.171958643504313	FABP4/IL33/ITGA2/HYAL2/MEF2C/ETS1/HLA-E/OSMR/IFI16/MGST2/CD81/APP/MDK/IL6ST/GJA1/FYN/LAMP1/PARP9/PLSCR1/CLOCK/PAK2	21
GO:0051047	positive regulation of secretion	23/988	310/18722	0.0631896220106209	0.171958643504313	EDN1/IGF1/P2RY1/VEGFC/NNAT/NPR1/PRKCE/RGCC/KIF5B/GNAI2/SLC12A2/TGFB1/GJA1/ACSL3/LAMP1/RAB27A/HIF1A/SDCBP/CREB1/GATA2/PDCD6IP/SMAD4/RAB5A	23
GO:0006096	glycolytic process	8/988	81/18722	0.0634592546200309	0.172515639990586	IGF1/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	8
GO:2000106	regulation of leukocyte apoptotic process	8/988	81/18722	0.0634592546200309	0.172515639990586	IDO1/MEF2C/FOXP1/GIMAP8/PTEN/HIF1A/RAPGEF2/BCL10	8
GO:0018394	peptidyl-lysine acetylation	14/988	169/18722	0.0636096689130484	0.172750894113926	PCGF2/KMT2A/MSL1/OGT/GATA2/CLOCK/EID1/PRKAA1/KAT6A/DIP2A/ATF2/SMAD4/ZMPSTE24/KANSL1	14
GO:0001706	endoderm formation	6/988	54/18722	0.0639608088215536	0.172750894113926	SOX7/FN1/ITGA5/COL4A2/DUSP1/SMAD2	6
GO:0010524	positive regulation of calcium ion transport into cytosol	6/988	54/18722	0.0639608088215536	0.172750894113926	APLNR/RAMP3/F2R/CAV1/CALM1/PKD2	6
GO:0060350	endochondral bone morphogenesis	6/988	54/18722	0.0639608088215536	0.172750894113926	TEK/MEF2C/BMPR2/TGFBR2/SERPINH1/ZMPSTE24	6
GO:0070228	regulation of lymphocyte apoptotic process	6/988	54/18722	0.0639608088215536	0.172750894113926	IDO1/FOXP1/GIMAP8/PTEN/HIF1A/BCL10	6
GO:2000179	positive regulation of neural precursor cell proliferation	6/988	54/18722	0.0639608088215536	0.172750894113926	VEGFC/NOTCH1/MDK/GNAI2/FLNA/HIF1A	6
GO:0031667	response to nutrient levels	33/988	474/18722	0.0639869845603355	0.172750894113926	SPARC/NUAK1/ITGA2/BMPR2/FOXO1/SLC38A2/IFI16/TGFBR2/PDK4/GNAI2/ADRB1/CHSY1/CPT1A/ACSL3/PTEN/OGT/ZFP36/RALB/EIF2AK2/ACAT1/ABCA1/SLC2A1/CCND1/PRKAA1/XPR1/PLEC/KLF10/SH3GLB1/TNRC6A/BNIP2/MAPK1/BCL10/JUN	33
GO:0051052	regulation of DNA metabolic process	26/988	359/18722	0.0640528264816383	0.172750894113926	ACVRL1/DACH1/BMPR2/RGCC/PDGFB/DUSP1/PML/TGFB1/GJA1/ATRX/HMBOX1/PIK3CA/SLF2/KMT2A/KLF4/ACTR2/PARP9/DTX3L/NEK7/SMG1/TRIP12/KMT5B/RIF1/MAPK1/XRN1/ZMPSTE24	26
GO:0001916	positive regulation of T cell mediated cytotoxicity	4/988	29/18722	0.0641636886458537	0.172750894113926	HLA-E/HLA-A/HLA-B/B2M	4
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	4/988	29/18722	0.0641636886458537	0.172750894113926	FCGR2B/YES1/FYN/PLK2	4
GO:0006688	glycosphingolipid biosynthetic process	4/988	29/18722	0.0641636886458537	0.172750894113926	UGCG/ST3GAL5/PRKAA1/B4GALT5	4
GO:0010955	negative regulation of protein processing	4/988	29/18722	0.0641636886458537	0.172750894113926	THBS1/CARD16/XIAP/CARD8	4
GO:0040018	positive regulation of multicellular organism growth	4/988	29/18722	0.0641636886458537	0.172750894113926	IGF2/CREB1/CELF1/NIPBL	4
GO:0048679	regulation of axon regeneration	4/988	29/18722	0.0641636886458537	0.172750894113926	SCARF1/KLF4/PTEN/FLNA	4
GO:0062098	regulation of programmed necrotic cell death	4/988	29/18722	0.0641636886458537	0.172750894113926	CAV1/CFLAR/OGT/CYLD	4
GO:1902430	negative regulation of amyloid-beta formation	4/988	29/18722	0.0641636886458537	0.172750894113926	IGF1/CLU/RTN4/ROCK1	4
GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	4/988	29/18722	0.0641636886458537	0.172750894113926	ADGRA2/TSPAN12/MYO1C/ATP2B4	4
GO:1903318	negative regulation of protein maturation	4/988	29/18722	0.0641636886458537	0.172750894113926	THBS1/CARD16/XIAP/CARD8	4
GO:2001032	regulation of double-strand break repair via nonhomologous end joining	4/988	29/18722	0.0641636886458537	0.172750894113926	PARP9/DTX3L/KMT5B/RIF1	4
GO:0090174	organelle membrane fusion	10/988	110/18722	0.0652177162452162	0.175410890478273	STXBP6/CAV2/SYT11/KIF5B/STX3/TBC1D4/SAMD9/DYSF/SNAP23/YIPF4	10
GO:1904659	glucose transmembrane transport	10/988	110/18722	0.0652177162452162	0.175410890478273	EDN1/IGF1/FABP5/MEF2A/PEA15/YES1/ARPP19/SLC2A1/SLC2A3/RAP1A	10
GO:0002643	regulation of tolerance induction	3/988	18/18722	0.0661611405968483	0.176164400426295	HLA-B/TGFBR2/CBLB	3
GO:0006085	acetyl-CoA biosynthetic process	3/988	18/18722	0.0661611405968483	0.176164400426295	PDK4/ACAT1/DIP2A	3
GO:0030889	negative regulation of B cell proliferation	3/988	18/18722	0.0661611405968483	0.176164400426295	FCGR2B/PKN1/RC3H1	3
GO:0036507	protein demannosylation	3/988	18/18722	0.0661611405968483	0.176164400426295	EDEM3/MAN1A1/TRIM13	3
GO:0036508	protein alpha-1,2-demannosylation	3/988	18/18722	0.0661611405968483	0.176164400426295	EDEM3/MAN1A1/TRIM13	3
GO:0048486	parasympathetic nervous system development	3/988	18/18722	0.0661611405968483	0.176164400426295	NRP1/SEMA3F/HES1	3
GO:0048643	positive regulation of skeletal muscle tissue development	3/988	18/18722	0.0661611405968483	0.176164400426295	MEF2C/IGF2/PRKAA1	3
GO:0051447	negative regulation of meiotic cell cycle	3/988	18/18722	0.0661611405968483	0.176164400426295	RPS6KA2/DUSP1/PRKAR1A	3
GO:0060008	Sertoli cell differentiation	3/988	18/18722	0.0661611405968483	0.176164400426295	ATRX/FLNA/FNDC3A	3
GO:0060391	positive regulation of SMAD protein signal transduction	3/988	18/18722	0.0661611405968483	0.176164400426295	BMPR2/TGFB1/SMAD4	3
GO:0060438	trachea development	3/988	18/18722	0.0661611405968483	0.176164400426295	FOXF1/TGFBR2/MAPK1	3
GO:0060716	labyrinthine layer blood vessel development	3/988	18/18722	0.0661611405968483	0.176164400426295	VASH1/HES1/MAPK1	3
GO:0060973	cell migration involved in heart development	3/988	18/18722	0.0661611405968483	0.176164400426295	DCHS1/ENG/NOTCH1	3
GO:0061484	hematopoietic stem cell homeostasis	3/988	18/18722	0.0661611405968483	0.176164400426295	MYCT1/FSTL1/ADAR	3
GO:1900225	regulation of NLRP3 inflammasome complex assembly	3/988	18/18722	0.0661611405968483	0.176164400426295	CARD8/CD36/EIF2AK2	3
GO:1900242	regulation of synaptic vesicle endocytosis	3/988	18/18722	0.0661611405968483	0.176164400426295	SYT11/CALM1/ROCK1	3
GO:1902170	cellular response to reactive nitrogen species	3/988	18/18722	0.0661611405968483	0.176164400426295	FOXO1/CFLAR/CRK	3
GO:1902683	regulation of receptor localization to synapse	3/988	18/18722	0.0661611405968483	0.176164400426295	ADAM10/NPTN/RAP1A	3
GO:1905820	positive regulation of chromosome separation	3/988	18/18722	0.0661611405968483	0.176164400426295	RB1/PLSCR1/CDC27	3
GO:2000641	regulation of early endosome to late endosome transport	3/988	18/18722	0.0661611405968483	0.176164400426295	MSN/RDX/MAPK1	3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	7/988	68/18722	0.0666132360823853	0.177109072850491	IGF1/IL6ST/FYN/PARP14/PARP9/HES1/ARL2BP	7
GO:0051148	negative regulation of muscle cell differentiation	7/988	68/18722	0.0666132360823853	0.177109072850491	BMPR2/NOTCH1/IGF2/SMAD1/PDGFB/ID2/SMAD4	7
GO:0034614	cellular response to reactive oxygen species	13/988	155/18722	0.0666159502174852	0.177109072850491	FOXO1/ETS1/KLF2/RHOB/PCGF2/PXN/KLF4/SETX/CD36/PKD2/PRKAA1/MAPK1/JUN	13
GO:0006473	protein acetylation	16/988	201/18722	0.0666612365299731	0.177140814630924	FOXO1/PCGF2/TAOK1/KMT2A/MSL1/OGT/GATA2/CLOCK/EID1/PRKAA1/KAT6A/DIP2A/ATF2/SMAD4/ZMPSTE24/KANSL1	16
GO:0001910	regulation of leukocyte mediated cytotoxicity	8/988	82/18722	0.0672321294774926	0.178390145746474	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/B2M/LAMP1/CRK	8
GO:0006757	ATP generation from ADP	8/988	82/18722	0.0672321294774926	0.178390145746474	IGF1/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	8
GO:1905897	regulation of response to endoplasmic reticulum stress	8/988	82/18722	0.0672321294774926	0.178390145746474	FCGR2B/CAV1/CLU/SERINC3/ATXN3/TMBIM6/ATF6/HSPA1A	8
GO:0071867	response to monoamine	10/988	111/18722	0.0684605500317456	0.181406691268147	CAV2/ID1/APP/GNB1/GABPA/PDE4B/FLNA/ARPP19/ATP2B4/MAPK1	10
GO:0071869	response to catecholamine	10/988	111/18722	0.0684605500317456	0.181406691268147	CAV2/ID1/APP/GNB1/GABPA/PDE4B/FLNA/ARPP19/ATP2B4/MAPK1	10
GO:0009154	purine ribonucleotide catabolic process	5/988	42/18722	0.0687343082817007	0.181406691268147	NT5E/PDE4D/NUDT3/PDE4B/ACAT1	5
GO:0021795	cerebral cortex cell migration	5/988	42/18722	0.0687343082817007	0.181406691268147	DIXDC1/RHOA/SUN1/ZMIZ1/RTN4	5
GO:0032691	negative regulation of interleukin-1 beta production	5/988	42/18722	0.0687343082817007	0.181406691268147	IGF1/GIT1/CARD16/PML/CARD8	5
GO:0043507	positive regulation of JUN kinase activity	5/988	42/18722	0.0687343082817007	0.181406691268147	EDN1/FZD4/MAP4K2/SASH1/MAP3K11	5
GO:0045047	protein targeting to ER	5/988	42/18722	0.0687343082817007	0.181406691268147	SPCS3/TRAM1/SEC62/MAN1A1/SEC61A1	5
GO:0046596	regulation of viral entry into host cell	5/988	42/18722	0.0687343082817007	0.181406691268147	IFITM2/IFITM3/IFITM1/LGALS1/GSN	5
GO:0072595	maintenance of protein localization in organelle	5/988	42/18722	0.0687343082817007	0.181406691268147	PML/GJA1/SUN1/SP100/ARL2BP	5
GO:0001755	neural crest cell migration	6/988	55/18722	0.0687446667023306	0.181406691268147	FN1/NRP1/EFNB1/HIF1A/PHACTR4/SEMA3F	6
GO:0010676	positive regulation of cellular carbohydrate metabolic process	6/988	55/18722	0.0687446667023306	0.181406691268147	IGF1/NNMT/P2RY1/PRKCE/IGF2/ARPP19	6
GO:0046631	alpha-beta T cell activation	13/988	156/18722	0.0693430885249965	0.182894978274469	HLX/FOXP1/HLA-E/HLA-A/TGFBR2/CD81/TNFRSF14/RHOA/STAT3/RC3H1/CBLB/ATF2/HSPH1	13
GO:0016571	histone methylation	12/988	141/18722	0.0696109313157225	0.18341927933984	NNMT/MECOM/BCOR/KMT2E/ATRX/KMT2A/OGT/ASH1L/WDR82/KMT5B/RIF1/SMAD4	12
GO:0030183	B cell differentiation	12/988	141/18722	0.0696109313157225	0.18341927933984	FCGR2B/ITM2A/HHEX/ITGB1/MFNG/ZFP36L1/LGALS1/LYL1/KLF6/IRF2BP2/ZFP36L2/ID2	12
GO:0002695	negative regulation of leukocyte activation	15/988	187/18722	0.0702867955132041	0.185108308262836	FCGR2B/ADGRF5/LRRC32/HLX/CEACAM1/FOXF1/SYT11/MDK/PKN1/CD200/PRKAR1A/TNFRSF14/RC3H1/CBLB/ID2	15
GO:0046700	heterocycle catabolic process	31/988	445/18722	0.0703560573738441	0.185198898300228	VIM/IDO1/NT5E/PDE4D/ENTPD1/ZFP36L1/DICER1/PABPC1/OAS2/NUDT3/PDE4B/ZFP36/CSDE1/TNRC6B/CELF1/ACAT1/CNOT6L/ZC3HAV1/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/PUM2/ROCK2/SMG1/TNRC6A/ROCK1/CNOT2/HSPA1A/XRN1/BTG2	31
GO:0006605	protein targeting	23/988	314/18722	0.0706293644038537	0.185826242552388	ABLIM3/CLU/STOM/SCARB2/SPCS3/TRAM1/FYN/SEC62/GDI1/RAB27A/SDCBP/MAN1A1/VPS13C/MYO1C/LEPROT/PRKAA1/NUCB1/CHM/SH3GLB1/NEDD4/SEC61A1/GOLGA7/YWHAB	23
GO:0050688	regulation of defense response to virus	7/988	69/18722	0.0709295306622506	0.186064547304909	SEC14L1/TSPAN6/HTRA1/PCBP2/PARP9/DTX3L/ZMPSTE24	7
GO:0009410	response to xenobiotic stimulus	32/988	462/18722	0.0709805170503058	0.186064547304909	EDN1/CRHBP/NNMT/COL18A1/VEGFC/ITGA2/MEF2C/ENG/PAM/TXNIP/AHR/PPM1F/TGFBR2/B2M/LGALS1/RB1/MDK/CPT1A/DUSP6/FYN/PTEN/PDE4B/RHOA/PTPRM/CREB1/STAT3/ABCA1/PRKAA1/XPO1/PPP1R12A/JUN/RAP1A	32
GO:0007176	regulation of epidermal growth factor-activated receptor activity	4/988	30/18722	0.0710771574581708	0.186064547304909	APP/SHC1/SOCS4/CBLB	4
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	4/988	30/18722	0.0710771574581708	0.186064547304909	APP/CALM1/TGFB1/MAPK1	4
GO:0031571	mitotic G1 DNA damage checkpoint signaling	4/988	30/18722	0.0710771574581708	0.186064547304909	PML/CCND1/WAC/PLK2	4
GO:0033137	negative regulation of peptidyl-serine phosphorylation	4/988	30/18722	0.0710771574581708	0.186064547304909	CAV1/PDE4D/PPM1F/PTEN	4
GO:0034694	response to prostaglandin	4/988	30/18722	0.0710771574581708	0.186064547304909	EDN1/PRKCE/GNB1/PRKAA1	4
GO:0045070	positive regulation of viral genome replication	4/988	30/18722	0.0710771574581708	0.186064547304909	NOTCH1/PABPC1/ADAR/PKN2	4
GO:0051125	regulation of actin nucleation	4/988	30/18722	0.0710771574581708	0.186064547304909	NCKAP1/ABI2/GSN/WASL	4
GO:1902751	positive regulation of cell cycle G2/M phase transition	4/988	30/18722	0.0710771574581708	0.186064547304909	APP/CDC25B/CCND1/RAB11A	4
GO:0048678	response to axon injury	8/988	83/18722	0.0711402664864966	0.186064547304909	SCARF1/LAMB2/LGALS1/JAM3/KLF4/PTEN/FLNA/CTNNA1	8
GO:0061053	somite development	8/988	83/18722	0.0711402664864966	0.186064547304909	MEOX2/LRP6/TCF15/FOXF1/NOTCH1/PLXNA2/MIB1/SMAD4	8
GO:0002821	positive regulation of adaptive immune response	10/988	112/18722	0.0718040705648924	0.187615948273836	IL1R1/HLA-E/HLA-A/HLA-B/B2M/CD81/IL6ST/TGFB1/KMT5B/RIF1	10
GO:0043406	positive regulation of MAP kinase activity	10/988	112/18722	0.0718040705648924	0.187615948273836	EDN1/FZD4/FGFR1/THBS1/MAP4K2/PDGFB/SASH1/TGFB1/MAP3K11/IQGAP1	10
GO:1902107	positive regulation of leukocyte differentiation	13/988	157/18722	0.0721423370149631	0.188314542615963	HLX/TGFBR2/ZFP36L1/RB1/MDK/TGFB1/RHOA/CREB1/ZMIZ1/CD46/KLF10/ID2/JUN	13
GO:1903708	positive regulation of hemopoiesis	13/988	157/18722	0.0721423370149631	0.188314542615963	HLX/TGFBR2/ZFP36L1/RB1/MDK/TGFB1/RHOA/CREB1/ZMIZ1/CD46/KLF10/ID2/JUN	13
GO:0023061	signal release	32/988	463/18722	0.0725802150102812	0.189364490242934	EDN1/CRHBP/P2RY1/NNAT/FZD4/F2R/MEF2C/PCSK5/SYT11/PRKCE/KIF5B/GIT1/CALM1/CPT1A/GJA1/STX3/HIF1A/MAP4K4/CREB1/SLC30A1/ABCA1/SNAP23/TBX3/CLOCK/PPP3CA/PIM3/CTBP2/SMAD2/MIDN/SMAD4/RAB5A/RAP1A	32
GO:0002711	positive regulation of T cell mediated immunity	6/988	56/18722	0.0737300837100819	0.192175762840017	IL1R1/HLA-E/HLA-A/HLA-B/B2M/CD81	6
GO:0090175	regulation of establishment of planar polarity	6/988	56/18722	0.0737300837100819	0.192175762840017	RSPO3/SMURF2/RHOA/FZD6/DAAM1/CDC42	6
GO:0061337	cardiac conduction	9/988	98/18722	0.0738319525381418	0.192346901364693	CAV1/PDE4D/MEF2A/CALM1/GJA1/FLNA/ATP2B4/GJA5/ZMPSTE24	9
GO:0045776	negative regulation of blood pressure	5/988	43/18722	0.0745630101116588	0.194061102260231	VEGFC/BMPR2/PRCP/ADRB1/GJA5	5
GO:0090278	negative regulation of peptide hormone secretion	5/988	43/18722	0.0745630101116588	0.194061102260231	CRHBP/MAP4K4/PPP3CA/PIM3/MIDN	5
GO:0002088	lens development in camera-type eye	8/988	84/18722	0.075183955786582	0.194659853784927	VIM/TGFBR2/SKIL/CRYBG3/HIPK2/ABI2/SKI/HIPK1	8
GO:0010660	regulation of muscle cell apoptotic process	8/988	84/18722	0.075183955786582	0.194659853784927	EDN1/IGF1/LRP6/MDK/CFLAR/RGL2/PTEN/CAPN2	8
GO:0002708	positive regulation of lymphocyte mediated immunity	10/988	113/18722	0.0752486800777493	0.194659853784927	IL1R1/HLA-E/HLA-A/HLA-B/B2M/CD81/TGFB1/LAMP1/KMT5B/RIF1	10
GO:0060415	muscle tissue morphogenesis	7/988	70/18722	0.0754082786990881	0.194659853784927	HEG1/S1PR1/ENG/FKBP1A/NOTCH1/TGFB1/SMAD4	7
GO:0002902	regulation of B cell apoptotic process	3/988	19/18722	0.0755992617391385	0.194659853784927	FOXP1/PTEN/BCL10	3
GO:0003085	negative regulation of systemic arterial blood pressure	3/988	19/18722	0.0755992617391385	0.194659853784927	BMPR2/PRCP/ADRB1	3
GO:0006670	sphingosine metabolic process	3/988	19/18722	0.0755992617391385	0.194659853784927	PLPP1/SPTLC2/PLPP3	3
GO:0010885	regulation of cholesterol storage	3/988	19/18722	0.0755992617391385	0.194659853784927	SCARB1/CD36/ABCA1	3
GO:0030050	vesicle transport along actin filament	3/988	19/18722	0.0755992617391385	0.194659853784927	ACTN4/MYO1C/WASL	3
GO:0032011	ARF protein signal transduction	3/988	19/18722	0.0755992617391385	0.194659853784927	MAP4K4/CYTH1/ARFGEF3	3
GO:0032012	regulation of ARF protein signal transduction	3/988	19/18722	0.0755992617391385	0.194659853784927	MAP4K4/CYTH1/ARFGEF3	3
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	3/988	19/18722	0.0755992617391385	0.194659853784927	ACSL3/ELOVL5/HSD17B12	3
GO:0035728	response to hepatocyte growth factor	3/988	19/18722	0.0755992617391385	0.194659853784927	NRP1/CREB1/CRK	3
GO:0044546	NLRP3 inflammasome complex assembly	3/988	19/18722	0.0755992617391385	0.194659853784927	CARD8/CD36/EIF2AK2	3
GO:0045603	positive regulation of endothelial cell differentiation	3/988	19/18722	0.0755992617391385	0.194659853784927	ACVRL1/NOTCH1/VEZF1	3
GO:0051571	positive regulation of histone H3-K4 methylation	3/988	19/18722	0.0755992617391385	0.194659853784927	KMT2E/KMT2A/SMAD4	3
GO:0060065	uterus development	3/988	19/18722	0.0755992617391385	0.194659853784927	ASH1L/NIPBL/SMAD4	3
GO:0086014	atrial cardiac muscle cell action potential	3/988	19/18722	0.0755992617391385	0.194659853784927	GJA1/FLNA/GJA5	3
GO:0086026	atrial cardiac muscle cell to AV node cell signaling	3/988	19/18722	0.0755992617391385	0.194659853784927	GJA1/FLNA/GJA5	3
GO:0086066	atrial cardiac muscle cell to AV node cell communication	3/988	19/18722	0.0755992617391385	0.194659853784927	GJA1/FLNA/GJA5	3
GO:1901739	regulation of myoblast fusion	3/988	19/18722	0.0755992617391385	0.194659853784927	EHD2/CFLAR/CAPN2	3
GO:2000251	positive regulation of actin cytoskeleton reorganization	3/988	19/18722	0.0755992617391385	0.194659853784927	TEK/NRP1/CDC42	3
GO:0007631	feeding behavior	9/988	99/18722	0.0776169651891866	0.199565014077909	LEPR/P2RY1/DACH1/TCF15/APP/GLS/CPT1A/FYN/STAT3	9
GO:0031341	regulation of cell killing	9/988	99/18722	0.0776169651891866	0.199565014077909	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/B2M/LAMP1/CD59/CRK	9
GO:0051153	regulation of striated muscle cell differentiation	9/988	99/18722	0.0776169651891866	0.199565014077909	EDN1/IGF1/EFNB2/MEF2C/PIEZO1/NOTCH1/ATP11A/TGFB1/SMAD4	9
GO:0009755	hormone-mediated signaling pathway	15/988	190/18722	0.0781568426604921	0.200587280723335	CRHBP/PLPP1/PRCP/FOXP1/THRA/DDX17/PKN1/RHOA/ZMIZ1/CLOCK/NR1D2/NR3C1/CNOT2/NEDD4/ARID1A	15
GO:0030212	hyaluronan metabolic process	4/988	31/18722	0.0783544065325527	0.200587280723335	HYAL2/PDGFB/TGFB1/CD44	4
GO:0036257	multivesicular body organization	4/988	31/18722	0.0783544065325527	0.200587280723335	RAB27A/PDCD6IP/RAB11A/VPS36	4
GO:0044819	mitotic G1/S transition checkpoint signaling	4/988	31/18722	0.0783544065325527	0.200587280723335	PML/CCND1/WAC/PLK2	4
GO:0048384	retinoic acid receptor signaling pathway	4/988	31/18722	0.0783544065325527	0.200587280723335	KLF2/ACTN4/PML/CTBP2	4
GO:0048710	regulation of astrocyte differentiation	4/988	31/18722	0.0783544065325527	0.200587280723335	NOTCH1/IL6ST/HES1/ID2	4
GO:0055022	negative regulation of cardiac muscle tissue growth	4/988	31/18722	0.0783544065325527	0.200587280723335	TGFBR2/GJA1/PTEN/SAV1	4
GO:0061117	negative regulation of heart growth	4/988	31/18722	0.0783544065325527	0.200587280723335	TGFBR2/GJA1/PTEN/SAV1	4
GO:2000144	positive regulation of DNA-templated transcription, initiation	4/988	31/18722	0.0783544065325527	0.200587280723335	SETX/CREB1/MED13/JUN	4
GO:0002286	T cell activation involved in immune response	10/988	114/18722	0.0787946823565748	0.201520150543151	FCGR2B/HLX/CEACAM1/FOXP1/CD81/MDK/RAB27A/STAT3/RC3H1/CD46	10
GO:0008645	hexose transmembrane transport	10/988	114/18722	0.0787946823565748	0.201520150543151	EDN1/IGF1/FABP5/MEF2A/PEA15/YES1/ARPP19/SLC2A1/SLC2A3/RAP1A	10
GO:0006611	protein export from nucleus	6/988	57/18722	0.0789162756585804	0.201636967916488	IFI27/TGFB1/SP100/PTPN14/XPO1/CTDSPL2	6
GO:0060760	positive regulation of response to cytokine stimulus	6/988	57/18722	0.0789162756585804	0.201636967916488	EDN1/IL1R1/PARP14/HIF1A/PARP9/HSPA1A	6
GO:0010507	negative regulation of autophagy	8/988	85/18722	0.0793633038825097	0.202486969367863	LEPR/RASIP1/FEZ2/QSOX1/PIK3CA/STAT3/SMG1/EIF4G2	8
GO:0030433	ubiquitin-dependent ERAD pathway	8/988	85/18722	0.0793633038825097	0.202486969367863	CAV1/CANX/DNAJC10/SEL1L/HSP90B1/EDEM3/MAN1A1/TRIM13	8
GO:2000779	regulation of double-strand break repair	8/988	85/18722	0.0793633038825097	0.202486969367863	PML/SLF2/ACTR2/PARP9/DTX3L/TRIP12/KMT5B/RIF1	8
GO:0044270	cellular nitrogen compound catabolic process	31/988	451/18722	0.0804690010087827	0.205209473527918	VIM/IDO1/NT5E/PDE4D/ENTPD1/ZFP36L1/DICER1/PABPC1/OAS2/NUDT3/PDE4B/ZFP36/CSDE1/TNRC6B/CELF1/ACAT1/CNOT6L/ZC3HAV1/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/PUM2/ROCK2/SMG1/TNRC6A/ROCK1/CNOT2/HSPA1A/XRN1/BTG2	31
GO:0002792	negative regulation of peptide secretion	5/988	44/18722	0.080651325971738	0.205378640250178	CRHBP/MAP4K4/PPP3CA/PIM3/MIDN	5
GO:0021762	substantia nigra development	5/988	44/18722	0.080651325971738	0.205378640250178	CALM1/GNB4/RHOA/ZNF148/CDC42	5
GO:0046006	regulation of activated T cell proliferation	5/988	44/18722	0.080651325971738	0.205378640250178	IGF1/LRRC32/IGF2/PRKAR1A/RC3H1	5
GO:0035637	multicellular organismal signaling	13/988	160/18722	0.0809762412489488	0.206008521798092	S1PR1/ITGA2/CAV1/PDE4D/MEF2A/CALM1/JAM3/GJA1/FLNA/ATP2B4/GJA5/PLEC/ZMPSTE24	13
GO:0043271	negative regulation of ion transport	13/988	160/18722	0.0809762412489488	0.206008521798092	CAV1/CLIC2/SYT11/PRKCE/CALM1/SESTD1/PTEN/TMBIM6/SLC30A1/PKD2/CRBN/WNK1/NEDD4	13
GO:0009259	ribonucleotide metabolic process	27/988	385/18722	0.0813493225575792	0.206858593310608	IGF1/PAPSS2/NT5E/ADCY4/ZBTB20/NPR1/PDE4D/GIMAP7/TMSB4X/GIT1/PDK4/APP/TGFB1/NUDT3/ACSL3/PDE4B/ELOVL5/RHOA/HIF1A/HSD17B12/OGT/STAT3/ATP6V1A/ACAT1/PRKAA1/DIP2A/FAR1	27
GO:0051588	regulation of neurotransmitter transport	9/988	100/18722	0.0815182579650984	0.20718898866536	P2RY1/MEF2C/SYT11/ITGB1/GIT1/CALM1/SLC30A1/RAB5A/RAP1A	9
GO:0042476	odontogenesis	11/988	130/18722	0.0825061291669451	0.209499310771899	CD34/EDN1/FOXO1/ID3/PAM/BCOR/RHOA/HTRA1/CTNNA1/ATF2/ANKRD11	11
GO:0051028	mRNA transport	11/988	130/18722	0.0825061291669451	0.209499310771899	HHEX/ZFP36L1/RANBP2/QKI/ZFP36/ZC3H11A/MYO1C/FYTTD1/THOC2/SMG1/XPO1	11
GO:0009895	negative regulation of catabolic process	23/988	320/18722	0.0828816718091785	0.210251881876961	LEPR/RASIP1/TIMP1/GIT1/HIPK2/FEZ2/PABPC1/PML/FYN/QSOX1/PIK3CA/FLNA/OGT/RYBP/ZFP36/SDCBP/STAT3/ATP2B4/PRKAA1/WAC/SMG1/ROCK1/EIF4G2	23
GO:0071496	cellular response to external stimulus	23/988	320/18722	0.0828816718091785	0.210251881876961	NUAK1/ITGA2/ENG/BMPR2/FOXO1/PIEZO1/SLC38A2/IFI16/PDK4/GJA1/RALB/EIF2AK2/SLC2A1/F11R/PRKAA1/XPR1/PLEC/KLF10/SH3GLB1/TNRC6A/MAPK1/BCL10/JUN	23
GO:0009798	axis specification	8/988	86/18722	0.0836782341308798	0.211666085572968	SMAD6/NOTCH1/BCOR/SKI/TBX3/SMAD2/ETS2/SMAD4	8
GO:0015908	fatty acid transport	8/988	86/18722	0.0836782341308798	0.211666085572968	EDN1/FABP4/FABP5/THBS1/CPT1A/ACSL3/CD36/SLC2A1	8
GO:0032413	negative regulation of ion transmembrane transporter activity	8/988	86/18722	0.0836782341308798	0.211666085572968	CAV1/CLIC2/PRKCE/CALM1/PTEN/PKD2/CRBN/NEDD4	8
GO:0046928	regulation of neurotransmitter secretion	8/988	86/18722	0.0836782341308798	0.211666085572968	P2RY1/MEF2C/SYT11/GIT1/CALM1/SLC30A1/RAB5A/RAP1A	8
GO:0060761	negative regulation of response to cytokine stimulus	8/988	86/18722	0.0836782341308798	0.211666085572968	CAV1/SH2B3/CARD16/CARD8/KLF4/PARP14/ISG15/ADAR	8
GO:1903510	mucopolysaccharide metabolic process	8/988	86/18722	0.0836782341308798	0.211666085572968	NDNF/HYAL2/ANGPT1/PDGFB/CHSY1/TGFB1/GNS/CD44	8
GO:0002931	response to ischemia	6/988	58/18722	0.0843020487394616	0.212838632558945	NDNF/CAV1/RCAN1/GJA1/EGR1/ROCK2	6
GO:0032387	negative regulation of intracellular transport	6/988	58/18722	0.0843020487394616	0.212838632558945	ANGPT1/PKIG/MDFIC/GDI1/CD36/SP100	6
GO:0043525	positive regulation of neuron apoptotic process	6/988	58/18722	0.0843020487394616	0.212838632558945	ITGA1/MAP3K11/RHOA/ATF2/CDC42/JUN	6
GO:0086065	cell communication involved in cardiac conduction	6/988	58/18722	0.0843020487394616	0.212838632558945	CAV1/PDE4D/CALM1/GJA1/FLNA/GJA5	6
GO:0001736	establishment of planar polarity	7/988	72/18722	0.0848520147989274	0.213820636912667	RSPO3/SMURF2/EXOC5/RHOA/FZD6/DAAM1/CDC42	7
GO:0005977	glycogen metabolic process	7/988	72/18722	0.0848520147989274	0.213820636912667	IGF1/LEPR/PCDH12/IGF2/IL6ST/RB1CC1/GBE1	7
GO:0007164	establishment of tissue polarity	7/988	72/18722	0.0848520147989274	0.213820636912667	RSPO3/SMURF2/EXOC5/RHOA/FZD6/DAAM1/CDC42	7
GO:0070227	lymphocyte apoptotic process	7/988	72/18722	0.0848520147989274	0.213820636912667	IDO1/FOXP1/GIMAP8/PKN1/PTEN/HIF1A/BCL10	7
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	3/988	20/18722	0.0855922102676314	0.214768928172725	RB1/CDK17/ID2	3
GO:0006607	NLS-bearing protein import into nucleus	3/988	20/18722	0.0855922102676314	0.214768928172725	KPNA3/RANBP2/CBLB	3
GO:0032495	response to muramyl dipeptide	3/988	20/18722	0.0855922102676314	0.214768928172725	VIM/JAG1/NOTCH1	3
GO:0039535	regulation of RIG-I signaling pathway	3/988	20/18722	0.0855922102676314	0.214768928172725	SEC14L1/DDX60/PUM2	3
GO:0043691	reverse cholesterol transport	3/988	20/18722	0.0855922102676314	0.214768928172725	SCARB1/CLU/ABCA1	3
GO:0071379	cellular response to prostaglandin stimulus	3/988	20/18722	0.0855922102676314	0.214768928172725	PRKCE/GNB1/PRKAA1	3
GO:0097320	plasma membrane tubulation	3/988	20/18722	0.0855922102676314	0.214768928172725	EHD2/SH3GLB1/WASL	3
GO:0140632	inflammasome complex assembly	3/988	20/18722	0.0855922102676314	0.214768928172725	CARD8/CD36/EIF2AK2	3
GO:1902004	positive regulation of amyloid-beta formation	3/988	20/18722	0.0855922102676314	0.214768928172725	CLU/PICALM/ROCK2	3
GO:0006026	aminoglycan catabolic process	4/988	32/18722	0.0859871971998761	0.214947760717996	HYAL2/TGFB1/GNS/CD44	4
GO:0021799	cerebral cortex radially oriented cell migration	4/988	32/18722	0.0859871971998761	0.214947760717996	DIXDC1/SUN1/ZMIZ1/RTN4	4
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	4/988	32/18722	0.0859871971998761	0.214947760717996	THBS1/HIPK2/SDCBP/SMAD4	4
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	4/988	32/18722	0.0859871971998761	0.214947760717996	HHEX/PTEN/NR2F2/APC	4
GO:0090022	regulation of neutrophil chemotaxis	4/988	32/18722	0.0859871971998761	0.214947760717996	EDN1/MDK/JAM3/MOSPD2	4
GO:1901185	negative regulation of ERBB signaling pathway	4/988	32/18722	0.0859871971998761	0.214947760717996	ITGA1/SOCS4/CBLB/PTPN12	4
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	4/988	32/18722	0.0859871971998761	0.214947760717996	THBS1/HIPK2/SDCBP/SMAD4	4
GO:1903955	positive regulation of protein targeting to mitochondrion	4/988	32/18722	0.0859871971998761	0.214947760717996	ABLIM3/LEPROT/PRKAA1/SH3GLB1	4
GO:0015749	monosaccharide transmembrane transport	10/988	116/18722	0.0861915845340222	0.215357336333361	EDN1/IGF1/FABP5/MEF2A/PEA15/YES1/ARPP19/SLC2A1/SLC2A3/RAP1A	10
GO:0048285	organelle fission	33/988	488/18722	0.0866170070846504	0.21631854331625	EDN1/KDR/IGF1/HOXA13/RPS6KA2/CAV2/PLCB1/TMCC1/IGF2/RGCC/DDHD1/PDGFB/RB1/DUSP1/CDC25B/ATRX/PRKAR1A/PDS5B/SLF2/POGZ/FLNA/ACTR2/RHOA/SUN1/APC/STAG2/CDC27/PHIP/NIPBL/RALA/RAB11A/CDC42/HSPA1A	33
GO:0044088	regulation of vacuole organization	5/988	45/18722	0.0869960108447711	0.216959065543391	SCARB2/FEZ2/RALB/SH3GLB1/RAB5A	5
GO:0045933	positive regulation of muscle contraction	5/988	45/18722	0.0869960108447711	0.216959065543391	EDN1/ITGA2/F2R/RHOA/CTTN	5
GO:0060421	positive regulation of heart growth	5/988	45/18722	0.0869960108447711	0.216959065543391	EDN1/IGF1/MEF2C/NOTCH1/MAPK1	5
GO:0021953	central nervous system neuron differentiation	13/988	162/18722	0.0872316224047075	0.217444569785925	NFIB/NDNF/NOVA2/B2M/NRP1/PTEN/GATA2/ZMIZ1/RAPGEF2/HES1/B4GALT5/BTG2/NIN	13
GO:0009266	response to temperature stimulus	14/988	178/18722	0.0886121260744133	0.220695404903248	CD34/IGF1/FOXO1/THRA/THBS1/IGFBP7/ADRB1/TP53INP1/ATXN3/ERO1A/PLAC8/PRKAA1/HSPA1A/PSIP1	14
GO:0016331	morphogenesis of embryonic epithelium	12/988	147/18722	0.0886188438739888	0.220695404903248	VEGFC/DLC1/TGFB1/LUZP1/MIB1/HIF1A/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	12
GO:0002637	regulation of immunoglobulin production	7/988	73/18722	0.0898157834501101	0.222910094462279	FCGR2B/HLA-E/PKN1/TGFB1/TMBIM6/KMT5B/RIF1	7
GO:0006073	cellular glucan metabolic process	7/988	73/18722	0.0898157834501101	0.222910094462279	IGF1/LEPR/PCDH12/IGF2/IL6ST/RB1CC1/GBE1	7
GO:0032732	positive regulation of interleukin-1 production	7/988	73/18722	0.0898157834501101	0.222910094462279	IFI16/APP/CARD8/CD36/STAT3/EGR1/S100A13	7
GO:0044042	glucan metabolic process	7/988	73/18722	0.0898157834501101	0.222910094462279	IGF1/LEPR/PCDH12/IGF2/IL6ST/RB1CC1/GBE1	7
GO:0050848	regulation of calcium-mediated signaling	7/988	73/18722	0.0898157834501101	0.222910094462279	IGF1/LMCD1/ITPR1/RCAN1/CALM1/NFAT5/ATP2B4	7
GO:0061035	regulation of cartilage development	7/988	73/18722	0.0898157834501101	0.222910094462279	ACVRL1/LOXL2/BMPR2/SMAD1/MDK/EFEMP1/LTBP3	7
GO:0002820	negative regulation of adaptive immune response	6/988	59/18722	0.0898858099281252	0.222910094462279	FCGR2B/CEACAM1/AHR/TNFRSF14/RC3H1/CD46	6
GO:0032768	regulation of monooxygenase activity	6/988	59/18722	0.0898858099281252	0.222910094462279	CAV1/SCARB1/DDAH2/CALM1/HIF1A/ATP2B4	6
GO:0043407	negative regulation of MAP kinase activity	6/988	59/18722	0.0898858099281252	0.222910094462279	HYAL2/CAV1/SH2B3/DUSP1/AIDA/HIPK3	6
GO:0031396	regulation of protein ubiquitination	16/988	210/18722	0.090018668530955	0.223135402350179	NXN/CAV1/FKBP1A/PRKCE/ANGPT1/SASH1/XIAP/FYN/PTEN/ISG15/OGT/CBLB/DTX3L/TRIP12/HSPA1A/BCL10	16
GO:0071322	cellular response to carbohydrate stimulus	13/988	163/18722	0.0904696803432942	0.224148760253535	CALCRL/ZBTB20/RPS6KA2/PRKCE/ZFP36L1/KIF5B/LGALS1/PIK3CA/HIF1A/MAP4K4/PPP3CA/PIM3/PRKAA1	13
GO:0002443	leukocyte mediated immunity	30/988	440/18722	0.0911321279970557	0.225684785044457	FCGR2B/BST2/CFI/CEACAM1/FOXF1/JAG1/IL1R1/HLA-E/HLA-A/AHR/HLA-B/CLU/B2M/CD81/KIF5B/KMT2E/TGFB1/LYST/LAMP1/RAB27A/GATA2/SNAP23/S100A13/EMP2/TNFRSF1B/CRK/CD46/KMT5B/RIF1/BCL10	30
GO:0010212	response to ionizing radiation	12/988	148/18722	0.0920701606265918	0.227901534598535	THBD/IFI16/RHOB/PML/EGR1/CLOCK/CCND1/TRIM13/PRKAA1/NIPBL/IKBIP/ZMPSTE24	12
GO:0001843	neural tube closure	8/988	88/18722	0.092713625044946	0.227969772445035	DLC1/TGFB1/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	8
GO:0043543	protein acylation	18/988	243/18722	0.0928165799522002	0.227969772445035	FOXO1/PCGF2/TAOK1/KMT2A/MSL1/OGT/GATA2/CLOCK/EID1/PRKAA1/ZDHHC17/KAT6A/DIP2A/ATF2/SMAD4/GOLGA7/ZMPSTE24/KANSL1	18
GO:0010565	regulation of cellular ketone metabolic process	11/988	133/18722	0.0932995413292555	0.227969772445035	CEACAM1/CAV1/PRKCE/FABP5/PDK4/CPT1A/LPGAT1/ELOVL5/EGR1/ATP2B4/STARD4	11
GO:0006195	purine nucleotide catabolic process	5/988	46/18722	0.0935931799682072	0.227969772445035	NT5E/PDE4D/NUDT3/PDE4B/ACAT1	5
GO:0043300	regulation of leukocyte degranulation	5/988	46/18722	0.0935931799682072	0.227969772445035	FCGR2B/CEACAM1/FOXF1/LAMP1/GATA2	5
GO:0072599	establishment of protein localization to endoplasmic reticulum	5/988	46/18722	0.0935931799682072	0.227969772445035	SPCS3/TRAM1/SEC62/MAN1A1/SEC61A1	5
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	5/988	46/18722	0.0935931799682072	0.227969772445035	PLCB1/RGCC/KMT2E/RDX/CCND1	5
GO:0009135	purine nucleoside diphosphate metabolic process	9/988	103/18722	0.0939194397529738	0.227969772445035	IGF1/NT5E/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	9
GO:0009179	purine ribonucleoside diphosphate metabolic process	9/988	103/18722	0.0939194397529738	0.227969772445035	IGF1/NT5E/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	9
GO:0030148	sphingolipid biosynthetic process	9/988	103/18722	0.0939194397529738	0.227969772445035	PLPP1/SPTLC2/UGCG/PRKD3/ST3GAL5/PLPP3/ELOVL5/PRKAA1/B4GALT5	9
GO:0050773	regulation of dendrite development	9/988	103/18722	0.0939194397529738	0.227969772445035	ID1/ACTR2/RHOA/RAPGEF2/IQGAP1/PPP3CA/CRK/NEDD4/CAMSAP2	9
GO:0002335	mature B cell differentiation	4/988	33/18722	0.0939661609270771	0.227969772445035	FCGR2B/ITM2A/MFNG/LGALS1	4
GO:0009648	photoperiodism	4/988	33/18722	0.0939661609270771	0.227969772445035	PML/CLOCK/ID2/BHLHE40	4
GO:0010165	response to X-ray	4/988	33/18722	0.0939661609270771	0.227969772445035	THBD/CCND1/NIPBL/IKBIP	4
GO:0048048	embryonic eye morphogenesis	4/988	33/18722	0.0939661609270771	0.227969772445035	HIPK2/PHACTR4/HIPK1/EFEMP1	4
GO:0050901	leukocyte tethering or rolling	4/988	33/18722	0.0939661609270771	0.227969772445035	JAM2/SELP/ITGB1/ROCK1	4
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	4/988	33/18722	0.0939661609270771	0.227969772445035	THRA/CREB1/MED13/ATF7IP	4
GO:1902692	regulation of neuroblast proliferation	4/988	33/18722	0.0939661609270771	0.227969772445035	VEGFC/NOTCH1/HIF1A/CTNNA1	4
GO:1904030	negative regulation of cyclin-dependent protein kinase activity	4/988	33/18722	0.0939661609270771	0.227969772445035	HHEX/PTEN/NR2F2/APC	4
GO:0034219	carbohydrate transmembrane transport	10/988	118/18722	0.0939952194820605	0.227969772445035	EDN1/IGF1/FABP5/MEF2A/PEA15/YES1/ARPP19/SLC2A1/SLC2A3/RAP1A	10
GO:0001865	NK T cell differentiation	2/988	10/18722	0.0945010238938189	0.227969772445035	TGFBR2/ATF2	2
GO:0001915	negative regulation of T cell mediated cytotoxicity	2/988	10/18722	0.0945010238938189	0.227969772445035	FCGR2B/CEACAM1	2
GO:0002524	hypersensitivity	2/988	10/18722	0.0945010238938189	0.227969772445035	FCGR2B/HLA-E	2
GO:0002887	negative regulation of myeloid leukocyte mediated immunity	2/988	10/18722	0.0945010238938189	0.227969772445035	FCGR2B/FOXF1	2
GO:0003056	regulation of vascular associated smooth muscle contraction	2/988	10/18722	0.0945010238938189	0.227969772445035	DOCK4/RHOA	2
GO:0009950	dorsal/ventral axis specification	2/988	10/18722	0.0945010238938189	0.227969772445035	SMAD6/SMAD2	2
GO:0010728	regulation of hydrogen peroxide biosynthetic process	2/988	10/18722	0.0945010238938189	0.227969772445035	FYN/STAT3	2
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	2/988	10/18722	0.0945010238938189	0.227969772445035	ERO1A/EGLN1	2
GO:0021932	hindbrain radial glia guided cell migration	2/988	10/18722	0.0945010238938189	0.227969772445035	ITGB1/FLNA	2
GO:0031642	negative regulation of myelination	2/988	10/18722	0.0945010238938189	0.227969772445035	JAM2/PTEN	2
GO:0032275	luteinizing hormone secretion	2/988	10/18722	0.0945010238938189	0.227969772445035	TBX3/SMAD4	2
GO:0033131	regulation of glucokinase activity	2/988	10/18722	0.0945010238938189	0.227969772445035	RANBP2/MIDN	2
GO:0034085	establishment of sister chromatid cohesion	2/988	10/18722	0.0945010238938189	0.227969772445035	RB1/NIPBL	2
GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	2/988	10/18722	0.0945010238938189	0.227969772445035	NNMT/PARP9	2
GO:0035907	dorsal aorta development	2/988	10/18722	0.0945010238938189	0.227969772445035	ACVRL1/ENG	2
GO:0040015	negative regulation of multicellular organism growth	2/988	10/18722	0.0945010238938189	0.227969772445035	ADRB1/PLAC8	2
GO:0042045	epithelial fluid transport	2/988	10/18722	0.0945010238938189	0.227969772445035	EDN1/ITPR1	2
GO:0045835	negative regulation of meiotic nuclear division	2/988	10/18722	0.0945010238938189	0.227969772445035	RPS6KA2/PRKAR1A	2
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	2/988	10/18722	0.0945010238938189	0.227969772445035	CALM1/EGLN1	2
GO:0051918	negative regulation of fibrinolysis	2/988	10/18722	0.0945010238938189	0.227969772445035	THBD/THBS1	2
GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	2/988	10/18722	0.0945010238938189	0.227969772445035	PLSCR1/RAP1A	2
GO:0060439	trachea morphogenesis	2/988	10/18722	0.0945010238938189	0.227969772445035	TGFBR2/MAPK1	2
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	2/988	10/18722	0.0945010238938189	0.227969772445035	MAP4K4/PIM3	2
GO:0072070	loop of Henle development	2/988	10/18722	0.0945010238938189	0.227969772445035	JAG1/PKD2	2
GO:0090043	regulation of tubulin deacetylation	2/988	10/18722	0.0945010238938189	0.227969772445035	FRY/PRKAA1	2
GO:0090527	actin filament reorganization	2/988	10/18722	0.0945010238938189	0.227969772445035	NEDD9/GSN	2
GO:0097278	complement-dependent cytotoxicity	2/988	10/18722	0.0945010238938189	0.227969772445035	CD59/RAB27A	2
GO:0098903	regulation of membrane repolarization during action potential	2/988	10/18722	0.0945010238938189	0.227969772445035	CAV1/FLNA	2
GO:0098917	retrograde trans-synaptic signaling	2/988	10/18722	0.0945010238938189	0.227969772445035	PLCB1/FABP5	2
GO:1900246	positive regulation of RIG-I signaling pathway	2/988	10/18722	0.0945010238938189	0.227969772445035	DDX60/PUM2	2
GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	2/988	10/18722	0.0945010238938189	0.227969772445035	PICALM/ROCK2	2
GO:1904779	regulation of protein localization to centrosome	2/988	10/18722	0.0945010238938189	0.227969772445035	BICD1/APC	2
GO:2000169	regulation of peptidyl-cysteine S-nitrosylation	2/988	10/18722	0.0945010238938189	0.227969772445035	NCOA7/ATP2B4	2
GO:2000288	positive regulation of myoblast proliferation	2/988	10/18722	0.0945010238938189	0.227969772445035	MALAT1/ATF2	2
GO:2000434	regulation of protein neddylation	2/988	10/18722	0.0945010238938189	0.227969772445035	EPAS1/HIF1A	2
GO:2001223	negative regulation of neuron migration	2/988	10/18722	0.0945010238938189	0.227969772445035	COL3A1/STAT3	2
GO:0071897	DNA biosynthetic process	14/988	180/18722	0.0949041922824507	0.228612430195785	ACVRL1/DACH1/BMPR2/RGCC/REV3L/PDGFB/DUSP1/GJA1/HMBOX1/KLF4/POLK/NEK7/MAPK1/XRN1	14
GO:0002437	inflammatory response to antigenic stimulus	7/988	74/18722	0.0949395747386863	0.228612430195785	FCGR2B/HLA-E/NOTCH1/CD81/YES1/FYN/PLK2	7
GO:0046323	glucose import	7/988	74/18722	0.0949395747386863	0.228612430195785	IGF1/MEF2A/PEA15/ARPP19/SLC2A1/SLC2A3/RAP1A	7
GO:0046470	phosphatidylcholine metabolic process	7/988	74/18722	0.0949395747386863	0.228612430195785	ENPP2/SCARB1/FABP5/ACSL3/CAPN2/SLC44A2/SLC44A1	7
GO:0002712	regulation of B cell mediated immunity	6/988	60/18722	0.0956655785860846	0.228839096260475	FCGR2B/HLA-E/TGFB1/CD46/KMT5B/RIF1	6
GO:0002889	regulation of immunoglobulin mediated immune response	6/988	60/18722	0.0956655785860846	0.228839096260475	FCGR2B/HLA-E/TGFB1/CD46/KMT5B/RIF1	6
GO:0061951	establishment of protein localization to plasma membrane	6/988	60/18722	0.0956655785860846	0.228839096260475	SPTBN1/MACF1/VAMP5/ACSL3/RAB11A/GOLGA7	6
GO:0007063	regulation of sister chromatid cohesion	3/988	21/18722	0.0961106972434338	0.228839096260475	RB1/ATRX/SLF2	3
GO:0007350	blastoderm segmentation	3/988	21/18722	0.0961106972434338	0.228839096260475	NRP1/SEMA3F/TBX3	3
GO:0007617	mating behavior	3/988	21/18722	0.0961106972434338	0.228839096260475	THRA/APP/PTEN	3
GO:0008090	retrograde axonal transport	3/988	21/18722	0.0961106972434338	0.228839096260475	DST/KIF5B/DYNC1H1	3
GO:0010766	negative regulation of sodium ion transport	3/988	21/18722	0.0961106972434338	0.228839096260475	PRKCE/WNK1/NEDD4	3
GO:0022010	central nervous system myelination	3/988	21/18722	0.0961106972434338	0.228839096260475	CLU/PTEN/B4GALT5	3
GO:0030449	regulation of complement activation	3/988	21/18722	0.0961106972434338	0.228839096260475	A2M/CD59/CD46	3
GO:0032291	axon ensheathment in central nervous system	3/988	21/18722	0.0961106972434338	0.228839096260475	CLU/PTEN/B4GALT5	3
GO:0032516	positive regulation of phosphoprotein phosphatase activity	3/988	21/18722	0.0961106972434338	0.228839096260475	ITGA1/CALM1/PPP1R12A	3
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	3/988	21/18722	0.0961106972434338	0.228839096260475	NCKAP1/ABI2/WASL	3
GO:0035020	regulation of Rac protein signal transduction	3/988	21/18722	0.0961106972434338	0.228839096260475	OGT/CRK/ARHGAP17	3
GO:0035813	regulation of renal sodium excretion	3/988	21/18722	0.0961106972434338	0.228839096260475	EDN1/NPR1/GNAI2	3
GO:0046519	sphingoid metabolic process	3/988	21/18722	0.0961106972434338	0.228839096260475	PLPP1/SPTLC2/PLPP3	3
GO:0050849	negative regulation of calcium-mediated signaling	3/988	21/18722	0.0961106972434338	0.228839096260475	ITPR1/RCAN1/ATP2B4	3
GO:0051767	nitric-oxide synthase biosynthetic process	3/988	21/18722	0.0961106972434338	0.228839096260475	EDN1/KDR/IL33	3
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	3/988	21/18722	0.0961106972434338	0.228839096260475	EDN1/KDR/IL33	3
GO:0072111	cell proliferation involved in kidney development	3/988	21/18722	0.0961106972434338	0.228839096260475	PDGFB/CFLAR/EGR1	3
GO:0090141	positive regulation of mitochondrial fission	3/988	21/18722	0.0961106972434338	0.228839096260475	KDR/DDHD1/RALA	3
GO:0099515	actin filament-based transport	3/988	21/18722	0.0961106972434338	0.228839096260475	ACTN4/MYO1C/WASL	3
GO:1902307	positive regulation of sodium ion transmembrane transport	3/988	21/18722	0.0961106972434338	0.228839096260475	KIF5B/ACTN4/WNK1	3
GO:1905209	positive regulation of cardiocyte differentiation	3/988	21/18722	0.0961106972434338	0.228839096260475	EFNB2/MEF2C/TGFB1	3
GO:2001014	regulation of skeletal muscle cell differentiation	3/988	21/18722	0.0961106972434338	0.228839096260475	MEF2C/DDX17/NR1D2	3
GO:0046661	male sex differentiation	13/988	165/18722	0.0971669181520557	0.231250299831416	HOXA13/TNFSF10/ADAM15/SMAD5/ATRX/FLNA/RNF38/FNDC3A/CSDE1/TBX3/CTNNA1/CCND1/SMAD4	13
GO:0060606	tube closure	8/988	89/18722	0.0974330277029289	0.231779777500205	DLC1/TGFB1/SKI/PHACTR4/FZD6/HECTD1/RALA/BCL10	8
GO:1901361	organic cyclic compound catabolic process	33/988	495/18722	0.099756289769109	0.237200273613924	VIM/IDO1/NT5E/SCARF1/SCARB1/PDE4D/ENTPD1/ZFP36L1/DICER1/PABPC1/OAS2/NUDT3/PDE4B/ZFP36/CSDE1/TNRC6B/CELF1/ACAT1/CNOT6L/ZC3HAV1/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/PUM2/ROCK2/SMG1/TNRC6A/ROCK1/CNOT2/HSPA1A/XRN1/BTG2	33
GO:0048662	negative regulation of smooth muscle cell proliferation	7/988	75/18722	0.100222138971604	0.237706363425715	NPR1/MEF2C/BMPR2/IGFBP3/KLF4/PTEN/RHOA	7
GO:0061333	renal tubule morphogenesis	7/988	75/18722	0.100222138971604	0.237706363425715	DCHS1/MEF2C/COL4A1/PKD2/HES1/SMAD4/MTSS1	7
GO:0009261	ribonucleotide catabolic process	5/988	47/18722	0.100438342606077	0.237706363425715	NT5E/PDE4D/NUDT3/PDE4B/ACAT1	5
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	5/988	47/18722	0.100438342606077	0.237706363425715	CARD16/CARD8/CYLD/HIPK1/HSPA1A	5
GO:0019884	antigen processing and presentation of exogenous antigen	5/988	47/18722	0.100438342606077	0.237706363425715	FCGR2B/HLA-E/HLA-A/B2M/LNPEP	5
GO:0042311	vasodilation	5/988	47/18722	0.100438342606077	0.237706363425715	ITGA1/KLF2/ADRB1/GJA1/GJA5	5
GO:0048512	circadian behavior	5/988	47/18722	0.100438342606077	0.237706363425715	ADRB1/PTEN/EGR1/NR1D2/ID2	5
GO:0061001	regulation of dendritic spine morphogenesis	5/988	47/18722	0.100438342606077	0.237706363425715	PDLIM5/PTEN/ACTR2/ABI2/ADAM10	5
GO:0090279	regulation of calcium ion import	5/988	47/18722	0.100438342606077	0.237706363425715	RAMP3/PDGFB/FYN/SLC30A1/PKD2	5
GO:1900744	regulation of p38MAPK cascade	5/988	47/18722	0.100438342606077	0.237706363425715	SASH1/MAP3K3/DUSP1/CYLD/PJA2	5
GO:0031330	negative regulation of cellular catabolic process	19/988	262/18722	0.100461367825815	0.237706363425715	LEPR/RASIP1/TIMP1/HIPK2/FEZ2/PABPC1/PML/QSOX1/PIK3CA/OGT/RYBP/ZFP36/SDCBP/STAT3/ATP2B4/WAC/SMG1/ROCK1/EIF4G2	19
GO:0030199	collagen fibril organization	6/988	61/18722	0.101638999141577	0.240385736170997	COL3A1/LOXL2/TLL1/RB1/SERPINH1/CRTAP	6
GO:0009649	entrainment of circadian clock	4/988	34/18722	0.102280908001244	0.240736687831697	GNAQ/PML/ID2/BHLHE40	4
GO:0016242	negative regulation of macroautophagy	4/988	34/18722	0.102280908001244	0.240736687831697	FEZ2/QSOX1/PIK3CA/SMG1	4
GO:0034383	low-density lipoprotein particle clearance	4/988	34/18722	0.102280908001244	0.240736687831697	SCARB1/CD36/LIPA/HNRNPK	4
GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	4/988	34/18722	0.102280908001244	0.240736687831697	SEC14L1/DDX60/TSPAN6/PUM2	4
GO:0048854	brain morphogenesis	4/988	34/18722	0.102280908001244	0.240736687831697	AKT3/PTEN/FZD6/SOS1	4
GO:0050869	negative regulation of B cell activation	4/988	34/18722	0.102280908001244	0.240736687831697	FCGR2B/PKN1/RC3H1/ID2	4
GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	4/988	34/18722	0.102280908001244	0.240736687831697	EDN1/S1PR1/F2R/LPAR6	4
GO:0051973	positive regulation of telomerase activity	4/988	34/18722	0.102280908001244	0.240736687831697	HMBOX1/KLF4/NEK7/MAPK1	4
GO:0070050	neuron cellular homeostasis	4/988	34/18722	0.102280908001244	0.240736687831697	P2RY1/TAOK1/PRKAA1/CLCN3	4
GO:0086004	regulation of cardiac muscle cell contraction	4/988	34/18722	0.102280908001244	0.240736687831697	CAV1/PDE4D/PDE4B/GJA5	4
GO:0070664	negative regulation of leukocyte proliferation	8/988	90/18722	0.102285900684514	0.240736687831697	FCGR2B/IL33/LRRC32/PKN1/PRKAR1A/TNFRSF14/RC3H1/CBLB	8
GO:0040029	regulation of gene expression, epigenetic	9/988	105/18722	0.102765299462934	0.24175787012715	KLF2/XIST/IFI16/IGF2/PCGF5/ZMIZ1/ATF7IP/ARID1A/BAZ2A	9
GO:0048193	Golgi vesicle transport	21/988	296/18722	0.103861671159038	0.244228949622315	SPTBN1/STXBP6/EXOC6/MACF1/VAMP5/EXOC5/PLPP3/ACSL3/LAMP1/SCAMP1/BCAP29/TAPBP/VPS13C/SNAP23/YIPF4/ERGIC1/SEC23A/SEC31A/MON2/TMED7/GOLGA7	21
GO:0006163	purine nucleotide metabolic process	27/988	396/18722	0.104477300968674	0.24545927587156	IGF1/PAPSS2/NT5E/ADCY4/ZBTB20/NPR1/PDE4D/GIMAP7/TMSB4X/GIT1/PDK4/APP/TGFB1/NUDT3/ACSL3/PDE4B/ELOVL5/RHOA/HIF1A/HSD17B12/OGT/STAT3/ATP6V1A/ACAT1/PRKAA1/DIP2A/FAR1	27
GO:0019693	ribose phosphate metabolic process	27/988	396/18722	0.104477300968674	0.24545927587156	IGF1/PAPSS2/NT5E/ADCY4/ZBTB20/NPR1/PDE4D/GIMAP7/TMSB4X/GIT1/PDK4/APP/TGFB1/NUDT3/ACSL3/PDE4B/ELOVL5/RHOA/HIF1A/HSD17B12/OGT/STAT3/ATP6V1A/ACAT1/PRKAA1/DIP2A/FAR1	27
GO:0043401	steroid hormone mediated signaling pathway	11/988	136/18722	0.104904716589693	0.246245627275496	PLPP1/FOXP1/DDX17/PKN1/RHOA/ZMIZ1/CLOCK/NR3C1/CNOT2/NEDD4/ARID1A	11
GO:0043624	cellular protein complex disassembly	11/988	136/18722	0.104904716589693	0.246245627275496	SPTBN1/SPTAN1/TAOK1/PIK3CA/TMOD3/RDX/ADD1/APC/GSN/DSTN/CAMSAP2	11
GO:0031669	cellular response to nutrient levels	16/988	215/18722	0.104998294734116	0.2463564229804	NUAK1/BMPR2/FOXO1/SLC38A2/IFI16/PDK4/RALB/EIF2AK2/SLC2A1/PRKAA1/XPR1/KLF10/SH3GLB1/TNRC6A/MAPK1/JUN	16
GO:0006305	DNA alkylation	7/988	76/18722	0.105661980077804	0.247694809432169	KMT2E/ATRX/PIK3CA/KMT2A/ATF7IP/BAZ2A/ZMPSTE24	7
GO:0006306	DNA methylation	7/988	76/18722	0.105661980077804	0.247694809432169	KMT2E/ATRX/PIK3CA/KMT2A/ATF7IP/BAZ2A/ZMPSTE24	7
GO:0042177	negative regulation of protein catabolic process	10/988	121/18722	0.106460340734986	0.249304057613486	TIMP1/HIPK2/PML/FYN/FLNA/OGT/RYBP/SDCBP/WAC/ROCK1	10
GO:0016573	histone acetylation	12/988	152/18722	0.106686605478096	0.249304057613486	PCGF2/KMT2A/MSL1/OGT/GATA2/CLOCK/EID1/KAT6A/ATF2/SMAD4/ZMPSTE24/KANSL1	12
GO:0006907	pinocytosis	3/988	22/18722	0.107124056564296	0.249304057613486	CAV1/EHD4/CDC42	3
GO:0021854	hypothalamus development	3/988	22/18722	0.107124056564296	0.249304057613486	NDNF/ETS1/NRP1	3
GO:0032069	regulation of nuclease activity	3/988	22/18722	0.107124056564296	0.249304057613486	OAS2/TMBIM6/HSPA1A	3
GO:0045663	positive regulation of myoblast differentiation	3/988	22/18722	0.107124056564296	0.249304057613486	MEF2C/PLCB1/IGFBP3	3
GO:0046058	cAMP metabolic process	3/988	22/18722	0.107124056564296	0.249304057613486	ADCY4/PDE4D/PDE4B	3
GO:0060343	trabecula formation	3/988	22/18722	0.107124056564296	0.249304057613486	TEK/ADGRG6/FKBP1A	3
GO:0060713	labyrinthine layer morphogenesis	3/988	22/18722	0.107124056564296	0.249304057613486	RSPO3/ZFP36L1/SOCS3	3
GO:1900120	regulation of receptor binding	3/988	22/18722	0.107124056564296	0.249304057613486	ADAM15/B2M/NRP1	3
GO:0001657	ureteric bud development	8/988	91/18722	0.107271275146112	0.249304057613486	DCHS1/SMAD6/SMAD5/SMAD1/PKD2/SMAD2/HES1/SMAD4	8
GO:0019935	cyclic-nucleotide-mediated signaling	8/988	91/18722	0.107271275146112	0.249304057613486	APLNR/NPR1/ADGRG6/PDE4D/AHR/THBS1/CD36/RAPGEF2	8
GO:0006090	pyruvate metabolic process	9/988	106/18722	0.10736026232335	0.249304057613486	IGF1/ZBTB20/GIT1/PDK4/APP/HIF1A/OGT/STAT3/PRKAA1	9
GO:0009185	ribonucleoside diphosphate metabolic process	9/988	106/18722	0.10736026232335	0.249304057613486	IGF1/NT5E/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	9
GO:0071887	leukocyte apoptotic process	9/988	106/18722	0.10736026232335	0.249304057613486	IDO1/MEF2C/FOXP1/GIMAP8/PKN1/PTEN/HIF1A/RAPGEF2/BCL10	9
GO:0002673	regulation of acute inflammatory response	5/988	48/18722	0.107526437020687	0.249304057613486	FCGR2B/HLA-E/OSMR/IL6ST/ASH1L	5
GO:0002686	negative regulation of leukocyte migration	5/988	48/18722	0.107526437020687	0.249304057613486	PLCB1/DUSP1/CD200/LRCH1/WASL	5
GO:0006111	regulation of gluconeogenesis	5/988	48/18722	0.107526437020687	0.249304057613486	NNMT/LEPR/RANBP2/OGT/ARPP19	5
GO:0042149	cellular response to glucose starvation	5/988	48/18722	0.107526437020687	0.249304057613486	NUAK1/IFI16/SLC2A1/PRKAA1/SH3GLB1	5
GO:0045912	negative regulation of carbohydrate metabolic process	5/988	48/18722	0.107526437020687	0.249304057613486	LEPR/GIT1/TGFB1/STAT3/MIDN	5
GO:0016482	cytosolic transport	13/988	168/18722	0.107765215847878	0.249304057613486	MSN/KIF5B/LAMP1/FLNA/RDX/ACTR2/VPS13C/EMP2/SPAG9/MON2/TMEM87B/MAPK1/RAB5A	13
GO:0032613	interleukin-10 production	6/988	62/18722	0.107803354732338	0.249304057613486	CD34/FCGR2B/TRIB2/ISG15/STAT3/CD46	6
GO:0032615	interleukin-12 production	6/988	62/18722	0.107803354732338	0.249304057613486	FOXP1/PLCB1/THBS1/HLA-B/MDK/CD36	6
GO:0032623	interleukin-2 production	6/988	62/18722	0.107803354732338	0.249304057613486	CD34/SPTBN1/PDE4D/HDAC7/PDE4B/ZFP36	6
GO:0032653	regulation of interleukin-10 production	6/988	62/18722	0.107803354732338	0.249304057613486	CD34/FCGR2B/TRIB2/ISG15/STAT3/CD46	6
GO:0032655	regulation of interleukin-12 production	6/988	62/18722	0.107803354732338	0.249304057613486	FOXP1/PLCB1/THBS1/HLA-B/MDK/CD36	6
GO:0032663	regulation of interleukin-2 production	6/988	62/18722	0.107803354732338	0.249304057613486	CD34/SPTBN1/PDE4D/HDAC7/PDE4B/ZFP36	6
GO:0032731	positive regulation of interleukin-1 beta production	6/988	62/18722	0.107803354732338	0.249304057613486	IFI16/APP/CARD8/CD36/STAT3/EGR1	6
GO:0045576	mast cell activation	6/988	62/18722	0.107803354732338	0.249304057613486	FOXF1/NDRG1/GATA2/PLSCR1/SNAP23/S100A13	6
GO:0046824	positive regulation of nucleocytoplasmic transport	6/988	62/18722	0.107803354732338	0.249304057613486	HYAL2/TGFB1/FLNA/MAPK1/NEDD4/CTDSPL2	6
GO:0048663	neuron fate commitment	6/988	62/18722	0.107803354732338	0.249304057613486	ZNF521/NOTCH1/GATA2/CDC42/ID2/SMAD4	6
GO:0060048	cardiac muscle contraction	11/988	137/18722	0.108952617913699	0.250547312595502	CAV1/PDE4D/CLIC2/SMAD5/CALM1/GJA1/PIK3CA/PDE4B/FLNA/GJA5/GSN	11
GO:1903532	positive regulation of secretion by cell	20/988	282/18722	0.110567839623222	0.250547312595502	EDN1/IGF1/P2RY1/VEGFC/NNAT/PRKCE/RGCC/KIF5B/SLC12A2/TGFB1/GJA1/LAMP1/RAB27A/HIF1A/SDCBP/CREB1/GATA2/PDCD6IP/SMAD4/RAB5A	20
GO:0003298	physiological muscle hypertrophy	4/988	35/18722	0.1109201341302	0.250547312595502	EDN1/IGF1/SORBS2/PDLIM5	4
GO:0003301	physiological cardiac muscle hypertrophy	4/988	35/18722	0.1109201341302	0.250547312595502	EDN1/IGF1/SORBS2/PDLIM5	4
GO:0007020	microtubule nucleation	4/988	35/18722	0.1109201341302	0.250547312595502	GIT1/ARHGEF7/HSPA1A/NIN	4
GO:0010837	regulation of keratinocyte proliferation	4/988	35/18722	0.1109201341302	0.250547312595502	CD109/ZFP36L1/MDK/ZFP36	4
GO:0015695	organic cation transport	4/988	35/18722	0.1109201341302	0.250547312595502	SLC38A2/SEC14L1/SLC44A2/SLC44A1	4
GO:0018149	peptide cross-linking	4/988	35/18722	0.1109201341302	0.250547312595502	COL3A1/NDNF/FN1/THBS1	4
GO:0021955	central nervous system neuron axonogenesis	4/988	35/18722	0.1109201341302	0.250547312595502	NFIB/PTEN/B4GALT5/NIN	4
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	4/988	35/18722	0.1109201341302	0.250547312595502	OGT/RYBP/SDCBP/WAC	4
GO:0039694	viral RNA genome replication	4/988	35/18722	0.1109201341302	0.250547312595502	PCBP2/ROCK2/CDC42/RAB5A	4
GO:0061049	cell growth involved in cardiac muscle cell development	4/988	35/18722	0.1109201341302	0.250547312595502	EDN1/IGF1/SORBS2/PDLIM5	4
GO:0097421	liver regeneration	4/988	35/18722	0.1109201341302	0.250547312595502	SULF2/CPT1A/CCND1/RAP1A	4
GO:1905207	regulation of cardiocyte differentiation	4/988	35/18722	0.1109201341302	0.250547312595502	EFNB2/MEF2C/TGFB1/SMAD4	4
GO:0000380	alternative mRNA splicing, via spliceosome	7/988	77/18722	0.111257361912833	0.250547312595502	NOVA2/DDX17/MBNL1/CELF1/MBNL2/RBM5/DYRK1A	7
GO:0032418	lysosome localization	7/988	77/18722	0.111257361912833	0.250547312595502	FOXF1/KIF5B/MYH9/GATA2/SNAP23/S100A13/SPAG9	7
GO:0006937	regulation of muscle contraction	13/988	169/18722	0.111444844759114	0.250547312595502	EDN1/CALCRL/ITGA2/F2R/CAV1/PDE4D/CLIC2/DOCK4/CALM1/PDE4B/RHOA/CTTN/GJA5	13
GO:0009152	purine ribonucleotide biosynthetic process	13/988	169/18722	0.111444844759114	0.250547312595502	PAPSS2/ADCY4/NPR1/TMSB4X/PDK4/TGFB1/ACSL3/ELOVL5/HSD17B12/STAT3/ATP6V1A/ACAT1/DIP2A	13
GO:0002357	defense response to tumor cell	2/988	11/18722	0.111595433283313	0.250547312595502	RBMS3/KLF4	2
GO:0002604	regulation of dendritic cell antigen processing and presentation	2/988	11/18722	0.111595433283313	0.250547312595502	FCGR2B/THBS1	2
GO:0002645	positive regulation of tolerance induction	2/988	11/18722	0.111595433283313	0.250547312595502	TGFBR2/CBLB	2
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	2/988	11/18722	0.111595433283313	0.250547312595502	FCGR2B/CD46	2
GO:0003263	cardioblast proliferation	2/988	11/18722	0.111595433283313	0.250547312595502	NOTCH1/HES1	2
GO:0003264	regulation of cardioblast proliferation	2/988	11/18722	0.111595433283313	0.250547312595502	NOTCH1/HES1	2
GO:0006527	arginine catabolic process	2/988	11/18722	0.111595433283313	0.250547312595502	DDAH2/ATP2B4	2
GO:0006707	cholesterol catabolic process	2/988	11/18722	0.111595433283313	0.250547312595502	SCARF1/SCARB1	2
GO:0008611	ether lipid biosynthetic process	2/988	11/18722	0.111595433283313	0.250547312595502	AGPS/FAR1	2
GO:0014010	Schwann cell proliferation	2/988	11/18722	0.111595433283313	0.250547312595502	DICER1/SKI	2
GO:0016127	sterol catabolic process	2/988	11/18722	0.111595433283313	0.250547312595502	SCARF1/SCARB1	2
GO:0018342	protein prenylation	2/988	11/18722	0.111595433283313	0.250547312595502	PTAR1/CHM	2
GO:0021561	facial nerve development	2/988	11/18722	0.111595433283313	0.250547312595502	NRP1/SEMA3F	2
GO:0021604	cranial nerve structural organization	2/988	11/18722	0.111595433283313	0.250547312595502	NRP1/SEMA3F	2
GO:0021610	facial nerve morphogenesis	2/988	11/18722	0.111595433283313	0.250547312595502	NRP1/SEMA3F	2
GO:0032276	regulation of gonadotropin secretion	2/988	11/18722	0.111595433283313	0.250547312595502	GJA1/SMAD4	2
GO:0032329	serine transport	2/988	11/18722	0.111595433283313	0.250547312595502	SLC38A2/SERINC3	2
GO:0034115	negative regulation of heterotypic cell-cell adhesion	2/988	11/18722	0.111595433283313	0.250547312595502	KLF4/WNK1	2
GO:0035581	sequestering of extracellular ligand from receptor	2/988	11/18722	0.111595433283313	0.250547312595502	LTBP1/CD46	2
GO:0035865	cellular response to potassium ion	2/988	11/18722	0.111595433283313	0.250547312595502	CRHBP/SLC12A2	2
GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	2/988	11/18722	0.111595433283313	0.250547312595502	SEC14L1/TSPAN6	2
GO:0042789	mRNA transcription by RNA polymerase II	2/988	11/18722	0.111595433283313	0.250547312595502	FLNA/STAT3	2
GO:0043589	skin morphogenesis	2/988	11/18722	0.111595433283313	0.250547312595502	ITGA2/ITGA6	2
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2/988	11/18722	0.111595433283313	0.250547312595502	EPAS1/HIF1A	2
GO:0045657	positive regulation of monocyte differentiation	2/988	11/18722	0.111595433283313	0.250547312595502	ZFP36L1/JUN	2
GO:0046504	glycerol ether biosynthetic process	2/988	11/18722	0.111595433283313	0.250547312595502	AGPS/FAR1	2
GO:0048096	chromatin-mediated maintenance of transcription	2/988	11/18722	0.111595433283313	0.250547312595502	ZMIZ1/ARID1A	2
GO:0048103	somatic stem cell division	2/988	11/18722	0.111595433283313	0.250547312595502	NOTCH1/ZFP36L2	2
GO:0048680	positive regulation of axon regeneration	2/988	11/18722	0.111595433283313	0.250547312595502	SCARF1/FLNA	2
GO:0048715	negative regulation of oligodendrocyte differentiation	2/988	11/18722	0.111595433283313	0.250547312595502	NOTCH1/HES1	2
GO:0060312	regulation of blood vessel remodeling	2/988	11/18722	0.111595433283313	0.250547312595502	CEACAM1/TGFB1	2
GO:0060742	epithelial cell differentiation involved in prostate gland development	2/988	11/18722	0.111595433283313	0.250547312595502	NOTCH1/FEM1B	2
GO:0060837	blood vessel endothelial cell differentiation	2/988	11/18722	0.111595433283313	0.250547312595502	NOTCH1/NRP1	2
GO:0061314	Notch signaling involved in heart development	2/988	11/18722	0.111595433283313	0.250547312595502	JAG1/NOTCH1	2
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	2/988	11/18722	0.111595433283313	0.250547312595502	KLF4/WNK1	2
GO:0071679	commissural neuron axon guidance	2/988	11/18722	0.111595433283313	0.250547312595502	NFIB/NRP1	2
GO:0075522	IRES-dependent viral translational initiation	2/988	11/18722	0.111595433283313	0.250547312595502	CSDE1/PCBP2	2
GO:0075733	intracellular transport of virus	2/988	11/18722	0.111595433283313	0.250547312595502	BST2/KPNA3	2
GO:0097354	prenylation	2/988	11/18722	0.111595433283313	0.250547312595502	PTAR1/CHM	2
GO:0097384	cellular lipid biosynthetic process	2/988	11/18722	0.111595433283313	0.250547312595502	AGPS/FAR1	2
GO:0098935	dendritic transport	2/988	11/18722	0.111595433283313	0.250547312595502	KIF5B/PURA	2
GO:0099550	trans-synaptic signaling, modulating synaptic transmission	2/988	11/18722	0.111595433283313	0.250547312595502	F2R/NPTN	2
GO:1902033	regulation of hematopoietic stem cell proliferation	2/988	11/18722	0.111595433283313	0.250547312595502	N4BP2L2/EIF2AK2	2
GO:1902337	regulation of apoptotic process involved in morphogenesis	2/988	11/18722	0.111595433283313	0.250547312595502	NOTCH1/TNFRSF1B	2
GO:1902667	regulation of axon guidance	2/988	11/18722	0.111595433283313	0.250547312595502	NOVA2/NRP1	2
GO:1903299	regulation of hexokinase activity	2/988	11/18722	0.111595433283313	0.250547312595502	RANBP2/MIDN	2
GO:1904464	regulation of matrix metallopeptidase secretion	2/988	11/18722	0.111595433283313	0.250547312595502	SLC12A2/CD200	2
GO:1990773	matrix metallopeptidase secretion	2/988	11/18722	0.111595433283313	0.250547312595502	SLC12A2/CD200	2
GO:2000615	regulation of histone H3-K9 acetylation	2/988	11/18722	0.111595433283313	0.250547312595502	KMT2A/SMAD4	2
GO:2000786	positive regulation of autophagosome assembly	2/988	11/18722	0.111595433283313	0.250547312595502	RALB/SH3GLB1	2
GO:2001053	regulation of mesenchymal cell apoptotic process	2/988	11/18722	0.111595433283313	0.250547312595502	HOXA13/HIF1A	2
GO:0051054	positive regulation of DNA metabolic process	15/988	201/18722	0.11176840255435	0.250829638516565	RGCC/PDGFB/PML/TGFB1/ATRX/HMBOX1/SLF2/KLF4/ACTR2/PARP9/DTX3L/NEK7/KMT5B/RIF1/MAPK1	15
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	9/988	107/18722	0.112068952761206	0.251185770914568	IL1R1/HLA-E/HLA-A/HLA-B/B2M/CD81/TGFB1/KMT5B/RIF1	9
GO:0036503	ERAD pathway	9/988	107/18722	0.112068952761206	0.251185770914568	CAV1/CANX/DNAJC10/ATXN3/SEL1L/HSP90B1/EDEM3/MAN1A1/TRIM13	9
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	9/988	107/18722	0.112068952761206	0.251185770914568	IL33/HLA-E/THBS1/CLU/APP/OAS2/CD36/STAT3/BCL10	9
GO:0019439	aromatic compound catabolic process	31/988	467/18722	0.112156215660348	0.25127533428417	VIM/IDO1/NT5E/PDE4D/ENTPD1/ZFP36L1/DICER1/PABPC1/OAS2/NUDT3/PDE4B/ZFP36/CSDE1/TNRC6B/CELF1/ACAT1/CNOT6L/ZC3HAV1/RC3H1/TNFRSF1B/ZFP36L2/CNOT8/PUM2/ROCK2/SMG1/TNRC6A/ROCK1/CNOT2/HSPA1A/XRN1/BTG2	31
GO:0072163	mesonephric epithelium development	8/988	92/18722	0.112388011499867	0.25158243450792	DCHS1/SMAD6/SMAD5/SMAD1/PKD2/SMAD2/HES1/SMAD4	8
GO:0072164	mesonephric tubule development	8/988	92/18722	0.112388011499867	0.25158243450792	DCHS1/SMAD6/SMAD5/SMAD1/PKD2/SMAD2/HES1/SMAD4	8
GO:0055076	transition metal ion homeostasis	11/988	138/18722	0.113089700851337	0.253046542090271	HYAL2/EPAS1/B2M/APP/XIAP/HIF1A/ATP6V1A/SLC30A1/SLC30A7/PICALM/SMAD4	11
GO:0022617	extracellular matrix disassembly	6/988	63/18722	0.114155581697113	0.25532397893687	FSCN1/ADAM15/ETS1/LAMC1/TGFB1/ADAM10	6
GO:0002449	lymphocyte mediated immunity	24/988	350/18722	0.114843154680271	0.255697030188975	FCGR2B/CFI/CEACAM1/JAG1/IL1R1/HLA-E/HLA-A/AHR/HLA-B/CLU/B2M/CD81/KIF5B/TGFB1/LYST/LAMP1/RAB27A/EMP2/TNFRSF1B/CRK/CD46/KMT5B/RIF1/BCL10	24
GO:0007622	rhythmic behavior	5/988	49/18722	0.114851866346177	0.255697030188975	ADRB1/PTEN/EGR1/NR1D2/ID2	5
GO:0009409	response to cold	5/988	49/18722	0.114851866346177	0.255697030188975	FOXO1/THRA/ADRB1/PLAC8/PRKAA1	5
GO:0018198	peptidyl-cysteine modification	5/988	49/18722	0.114851866346177	0.255697030188975	NCOA7/ATP2B4/ZDHHC17/TMX3/GOLGA7	5
GO:0042304	regulation of fatty acid biosynthetic process	5/988	49/18722	0.114851866346177	0.255697030188975	CEACAM1/FABP5/PDK4/LPGAT1/ELOVL5	5
GO:0043457	regulation of cellular respiration	5/988	49/18722	0.114851866346177	0.255697030188975	COX7A1/PIK3CA/RHOA/HIF1A/IFNAR1	5
GO:0051445	regulation of meiotic cell cycle	5/988	49/18722	0.114851866346177	0.255697030188975	RPS6KA2/PLCB1/DUSP1/CDC25B/PRKAR1A	5
GO:0060986	endocrine hormone secretion	5/988	49/18722	0.114851866346177	0.255697030188975	CRHBP/FZD4/GJA1/TBX3/SMAD4	5
GO:0070169	positive regulation of biomineral tissue development	5/988	49/18722	0.114851866346177	0.255697030188975	KL/MEF2C/BMPR2/TGFB1/ISG15	5
GO:0072666	establishment of protein localization to vacuole	5/988	49/18722	0.114851866346177	0.255697030188975	CLU/SCARB2/VPS13C/NEDD4/VPS36	5
GO:1904752	regulation of vascular associated smooth muscle cell migration	5/988	49/18722	0.114851866346177	0.255697030188975	MEF2C/DOCK4/PDGFB/RHOA/IQGAP1	5
GO:0019722	calcium-mediated signaling	15/988	202/18722	0.115196541285421	0.256356944829558	EDN1/KDR/IGF1/SELP/LMCD1/ITPR1/CLIC2/RCAN1/CALM1/NFAT5/PPP3R1/ATP2B4/PPP3CA/PRKAA1/ZMPSTE24	15
GO:0033138	positive regulation of peptidyl-serine phosphorylation	9/988	108/18722	0.116890492742343	0.26001771249888	RAMP3/CAV1/ANGPT1/FNIP2/APP/TGFB1/PIK3CA/ATP2B4/CD44	9
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	7/988	78/18722	0.117006315115191	0.260166406819546	THBS1/RPS6KA3/CARD16/XIAP/KLF4/CD44/PAK2	7
GO:1901019	regulation of calcium ion transmembrane transporter activity	8/988	93/18722	0.117634802880769	0.261454423808637	PDE4D/CLIC2/FKBP1A/CALM1/STIM2/PDE4B/AHNAK/PKD2	8
GO:0034764	positive regulation of transmembrane transport	16/988	219/18722	0.118019668583165	0.261739309950458	APLNR/IGF1/RAMP3/F2R/ITGB1/TMSB4X/MEF2A/KIF5B/ACTN4/CALM1/STIM2/FLNA/ARPP19/PKD2/WNK1/RAP1A	16
GO:2001020	regulation of response to DNA damage stimulus	16/988	219/18722	0.118019668583165	0.261739309950458	SKIL/CLU/PML/SLF2/ACTR2/PARP9/FEM1B/CD44/DTX3L/SMG1/TRIP12/DYRK1A/KMT5B/RIF1/HNRNPK/ZMPSTE24	16
GO:0006665	sphingolipid metabolic process	12/988	155/18722	0.118495844639167	0.261739309950458	ENPP2/PLPP1/SPTLC2/UGCG/PRKD3/ST3GAL5/SERINC3/SERINC1/PLPP3/ELOVL5/PRKAA1/B4GALT5	12
GO:0002052	positive regulation of neuroblast proliferation	3/988	23/18722	0.118600624821301	0.261739309950458	VEGFC/NOTCH1/HIF1A	3
GO:0006622	protein targeting to lysosome	3/988	23/18722	0.118600624821301	0.261739309950458	CLU/SCARB2/NEDD4	3
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	3/988	23/18722	0.118600624821301	0.261739309950458	HIP1/CBLB/PTPN12	3
GO:0016973	poly(A)+ mRNA export from nucleus	3/988	23/18722	0.118600624821301	0.261739309950458	HHEX/ZC3H11A/THOC2	3
GO:0018279	protein N-linked glycosylation via asparagine	3/988	23/18722	0.118600624821301	0.261739309950458	ST6GAL1/MAGT1/RPN1	3
GO:0034105	positive regulation of tissue remodeling	3/988	23/18722	0.118600624821301	0.261739309950458	PPP3CA/ROCK2/ROCK1	3
GO:0034695	response to prostaglandin E	3/988	23/18722	0.118600624821301	0.261739309950458	PRKCE/GNB1/PRKAA1	3
GO:0035812	renal sodium excretion	3/988	23/18722	0.118600624821301	0.261739309950458	EDN1/NPR1/GNAI2	3
GO:0042026	protein refolding	3/988	23/18722	0.118600624821301	0.261739309950458	FKBP1A/B2M/HSPA1A	3
GO:0043931	ossification involved in bone maturation	3/988	23/18722	0.118600624821301	0.261739309950458	IGF1/DCHS1/RHOA	3
GO:0060353	regulation of cell adhesion molecule production	3/988	23/18722	0.118600624821301	0.261739309950458	NOTCH4/CAV1/NOTCH1	3
GO:0060575	intestinal epithelial cell differentiation	3/988	23/18722	0.118600624821301	0.261739309950458	IL6ST/HIF1A/SAV1	3
GO:0071514	genetic imprinting	3/988	23/18722	0.118600624821301	0.261739309950458	IGF2/PIK3CA/PCGF5	3
GO:1900273	positive regulation of long-term synaptic potentiation	3/988	23/18722	0.118600624821301	0.261739309950458	APP/CREB1/NPTN	3
GO:0033044	regulation of chromosome organization	14/988	187/18722	0.119049171067066	0.26262009830077	RB1/DUSP1/PML/ATRX/HMBOX1/SLF2/APC/CDC27/ATF7IP/NEK7/SMG1/MAPK1/XRN1/SENP6	14
GO:0009132	nucleoside diphosphate metabolic process	10/988	124/18722	0.119827084313384	0.263341025461658	IGF1/NT5E/ZBTB20/ENTPD1/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	10
GO:0010923	negative regulation of phosphatase activity	4/988	36/18722	0.119871724315943	0.263341025461658	FKBP1A/GNAI2/ROCK2/ROCK1	4
GO:0038179	neurotrophin signaling pathway	4/988	36/18722	0.119871724315943	0.263341025461658	RAPGEF2/ZDHHC17/SOS1/RAP1A	4
GO:0042755	eating behavior	4/988	36/18722	0.119871724315943	0.263341025461658	P2RY1/TCF15/CPT1A/STAT3	4
GO:0044060	regulation of endocrine process	4/988	36/18722	0.119871724315943	0.263341025461658	CRHBP/F2R/GJA1/SMAD4	4
GO:0070897	transcription preinitiation complex assembly	4/988	36/18722	0.119871724315943	0.263341025461658	THRA/CREB1/ATF7IP/BAZ2A	4
GO:0090313	regulation of protein targeting to membrane	4/988	36/18722	0.119871724315943	0.263341025461658	STOM/FYN/GDI1/MYO1C	4
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	4/988	36/18722	0.119871724315943	0.263341025461658	SKIL/CLU/CD44/HNRNPK	4
GO:1903539	protein localization to postsynaptic membrane	4/988	36/18722	0.119871724315943	0.263341025461658	STX3/ADAM10/RAB11A/RAP1A	4
GO:1903749	positive regulation of establishment of protein localization to mitochondrion	4/988	36/18722	0.119871724315943	0.263341025461658	ABLIM3/LEPROT/PRKAA1/SH3GLB1	4
GO:0000209	protein polyubiquitination	17/988	236/18722	0.120371454809993	0.264329544419463	IFI27/HACE1/RNF144B/SMURF2/SASH1/XIAP/TTC3/RNF19A/LNPEP/SPOP/RC3H1/HECTD1/CDC27/DTX3L/TRIP12/UBE2E3/NEDD4	17
GO:0050771	negative regulation of axonogenesis	6/988	64/18722	0.120692284805671	0.264596540193035	NRP1/PTEN/GDI1/SEMA3F/RTN4/RUFY3	6
GO:0098930	axonal transport	6/988	64/18722	0.120692284805671	0.264596540193035	DST/KIF5B/ARMCX3/HIF1A/KIF1B/DYNC1H1	6
GO:1900076	regulation of cellular response to insulin stimulus	6/988	64/18722	0.120692284805671	0.264596540193035	GRB14/IGF2/GNAI2/SOCS3/MYO1C/PRKAA1	6
GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	6/988	64/18722	0.120692284805671	0.264596540193035	HIPK2/PML/OGT/RYBP/SDCBP/WAC	6
GO:0032410	negative regulation of transporter activity	9/988	109/18722	0.121823880846605	0.266967184429523	CAV1/CLIC2/PRKCE/CTTNBP2NL/CALM1/PTEN/PKD2/CRBN/NEDD4	9
GO:0010665	regulation of cardiac muscle cell apoptotic process	5/988	50/18722	0.122408535087889	0.267696228236667	MDK/CFLAR/RGL2/PTEN/CAPN2	5
GO:0060425	lung morphogenesis	5/988	50/18722	0.122408535087889	0.267696228236667	NFIB/FOXF1/TGFBR2/CDC42/MAPK1	5
GO:0110151	positive regulation of biomineralization	5/988	50/18722	0.122408535087889	0.267696228236667	KL/MEF2C/BMPR2/TGFB1/ISG15	5
GO:1901570	fatty acid derivative biosynthetic process	5/988	50/18722	0.122408535087889	0.267696228236667	PAM/ACSL3/ELOVL5/HSD17B12/FAR1	5
GO:1904738	vascular associated smooth muscle cell migration	5/988	50/18722	0.122408535087889	0.267696228236667	MEF2C/DOCK4/PDGFB/RHOA/IQGAP1	5
GO:0000245	spliceosomal complex assembly	7/988	79/18722	0.122906644467674	0.268674936383655	SETX/CELF1/SF3B1/LUC7L3/RBM5/SCAF11/PSIP1	7
GO:1990830	cellular response to leukemia inhibitory factor	8/988	94/18722	0.123010178957692	0.268790650194678	VEGFC/FZD4/SOCS3/PML/KLF4/CREB1/CTBP2/RIF1	8
GO:0048284	organelle fusion	11/988	141/18722	0.126031070962688	0.275165248234196	STXBP6/CAV2/SYT11/VAT1/KIF5B/STX3/TBC1D4/SAMD9/DYSF/SNAP23/YIPF4	11
GO:1903038	negative regulation of leukocyte cell-cell adhesion	11/988	141/18722	0.126031070962688	0.275165248234196	FCGR2B/LRRC32/HLX/CEACAM1/MDK/PRKAR1A/KLF4/TNFRSF14/RC3H1/CBLB/WNK1	11
GO:0000280	nuclear division	29/988	439/18722	0.126228417021867	0.275482888751091	EDN1/IGF1/HOXA13/RPS6KA2/CAV2/PLCB1/IGF2/RGCC/PDGFB/RB1/DUSP1/CDC25B/ATRX/PRKAR1A/PDS5B/SLF2/POGZ/FLNA/ACTR2/RHOA/SUN1/APC/STAG2/CDC27/PHIP/NIPBL/RAB11A/CDC42/HSPA1A	29
GO:0097193	intrinsic apoptotic signaling pathway	20/988	288/18722	0.128314119867056	0.275849667591956	CAV1/ITPR1/PPM1F/IFI16/SKIL/FNIP2/CLU/SERINC3/HIPK2/DNAJC10/PML/ERO1A/HIF1A/TMBIM6/CYLD/HIPK1/CD44/TNFRSF1B/HNRNPK/HSPA1A	20
GO:0048709	oligodendrocyte differentiation	8/988	95/18722	0.128512510066295	0.275849667591956	NOTCH1/CLU/MDK/PTEN/CD9/TNFRSF1B/HES1/B4GALT5	8
GO:1990823	response to leukemia inhibitory factor	8/988	95/18722	0.128512510066295	0.275849667591956	VEGFC/FZD4/SOCS3/PML/KLF4/CREB1/CTBP2/RIF1	8
GO:0009791	post-embryonic development	7/988	80/18722	0.12895593671726	0.275849667591956	HEG1/ITPR1/ATRX/KLF4/ASH1L/EFEMP1/SMAD2	7
GO:0032204	regulation of telomere maintenance	7/988	80/18722	0.12895593671726	0.275849667591956	PML/ATRX/HMBOX1/NEK7/SMG1/MAPK1/XRN1	7
GO:0071229	cellular response to acid chemical	7/988	80/18722	0.12895593671726	0.275849667591956	COL4A1/KLF2/FYN/PIK3CA/CAPN2/PKD2/PLEC	7
GO:0006623	protein targeting to vacuole	4/988	37/18722	0.129122853472513	0.275849667591956	CLU/SCARB2/VPS13C/NEDD4	4
GO:0032885	regulation of polysaccharide biosynthetic process	4/988	37/18722	0.129122853472513	0.275849667591956	IGF1/IGF2/PDGFB/TGFB1	4
GO:0033120	positive regulation of RNA splicing	4/988	37/18722	0.129122853472513	0.275849667591956	SLC38A2/SETX/DYRK1A/HSPA1A	4
GO:0051567	histone H3-K9 methylation	4/988	37/18722	0.129122853472513	0.275849667591956	MECOM/ATRX/ASH1L/RIF1	4
GO:0060306	regulation of membrane repolarization	4/988	37/18722	0.129122853472513	0.275849667591956	CAV1/FLNA/GJA5/ZMPSTE24	4
GO:0062237	protein localization to postsynapse	4/988	37/18722	0.129122853472513	0.275849667591956	STX3/ADAM10/RAB11A/RAP1A	4
GO:0001821	histamine secretion	2/988	12/18722	0.129408390745323	0.275849667591956	EDN1/SNAP23	2
GO:0002424	T cell mediated immune response to tumor cell	2/988	12/18722	0.129408390745323	0.275849667591956	HLA-A/AHR	2
GO:0002674	negative regulation of acute inflammatory response	2/988	12/18722	0.129408390745323	0.275849667591956	FCGR2B/ASH1L	2
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	2/988	12/18722	0.129408390745323	0.275849667591956	HLA-E/CD81	2
GO:0002903	negative regulation of B cell apoptotic process	2/988	12/18722	0.129408390745323	0.275849667591956	FOXP1/BCL10	2
GO:0003207	cardiac chamber formation	2/988	12/18722	0.129408390745323	0.275849667591956	MEF2C/NOTCH1	2
GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	2/988	12/18722	0.129408390745323	0.275849667591956	SEC62/SEC61A1	2
GO:0006703	estrogen biosynthetic process	2/988	12/18722	0.129408390745323	0.275849667591956	HSD17B2/HSD17B12	2
GO:0007614	short-term memory	2/988	12/18722	0.129408390745323	0.275849667591956	RCAN1/MDK	2
GO:0009886	post-embryonic animal morphogenesis	2/988	12/18722	0.129408390745323	0.275849667591956	ATRX/EFEMP1	2
GO:0014889	muscle atrophy	2/988	12/18722	0.129408390745323	0.275849667591956	CFLAR/GSN	2
GO:0016188	synaptic vesicle maturation	2/988	12/18722	0.129408390745323	0.275849667591956	PICALM/CLCN3	2
GO:0021559	trigeminal nerve development	2/988	12/18722	0.129408390745323	0.275849667591956	NRP1/SEMA3F	2
GO:0031953	negative regulation of protein autophosphorylation	2/988	12/18722	0.129408390745323	0.275849667591956	ENG/CAV1	2
GO:0033523	histone H2B ubiquitination	2/988	12/18722	0.129408390745323	0.275849667591956	WAC/DTX3L	2
GO:0033629	negative regulation of cell adhesion mediated by integrin	2/988	12/18722	0.129408390745323	0.275849667591956	JAM3/WNK1	2
GO:0035739	CD4-positive, alpha-beta T cell proliferation	2/988	12/18722	0.129408390745323	0.275849667591956	TGFBR2/CD81	2
GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	2/988	12/18722	0.129408390745323	0.275849667591956	COL4A1/COL4A2	2
GO:0038180	nerve growth factor signaling pathway	2/988	12/18722	0.129408390745323	0.275849667591956	RAPGEF2/RAP1A	2
GO:0042118	endothelial cell activation	2/988	12/18722	0.129408390745323	0.275849667591956	FOXP1/SMAD4	2
GO:0043129	surfactant homeostasis	2/988	12/18722	0.129408390745323	0.275849667591956	ADGRF5/EPAS1	2
GO:0043696	dedifferentiation	2/988	12/18722	0.129408390745323	0.275849667591956	PDGFB/CDK6	2
GO:0043697	cell dedifferentiation	2/988	12/18722	0.129408390745323	0.275849667591956	PDGFB/CDK6	2
GO:0045605	negative regulation of epidermal cell differentiation	2/988	12/18722	0.129408390745323	0.275849667591956	NOTCH1/HES1	2
GO:0045683	negative regulation of epidermis development	2/988	12/18722	0.129408390745323	0.275849667591956	NOTCH1/HES1	2
GO:0048548	regulation of pinocytosis	2/988	12/18722	0.129408390745323	0.275849667591956	CAV1/CDC42	2
GO:0051001	negative regulation of nitric-oxide synthase activity	2/988	12/18722	0.129408390745323	0.275849667591956	CAV1/ATP2B4	2
GO:0060442	branching involved in prostate gland morphogenesis	2/988	12/18722	0.129408390745323	0.275849667591956	HOXA13/FEM1B	2
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	2/988	12/18722	0.129408390745323	0.275849667591956	EDN1/IGF1	2
GO:0070572	positive regulation of neuron projection regeneration	2/988	12/18722	0.129408390745323	0.275849667591956	SCARF1/FLNA	2
GO:0070586	cell-cell adhesion involved in gastrulation	2/988	12/18722	0.129408390745323	0.275849667591956	KLF4/WNK1	2
GO:0071872	cellular response to epinephrine stimulus	2/988	12/18722	0.129408390745323	0.275849667591956	PDE4B/ATP2B4	2
GO:0072376	protein activation cascade	2/988	12/18722	0.129408390745323	0.275849667591956	FN1/PRCP	2
GO:0072520	seminiferous tubule development	2/988	12/18722	0.129408390745323	0.275849667591956	ATRX/SMAD4	2
GO:0072584	caveolin-mediated endocytosis	2/988	12/18722	0.129408390745323	0.275849667591956	CAV1/MAPK1	2
GO:0072683	T cell extravasation	2/988	12/18722	0.129408390745323	0.275849667591956	F11R/CRK	2
GO:0097152	mesenchymal cell apoptotic process	2/988	12/18722	0.129408390745323	0.275849667591956	HOXA13/HIF1A	2
GO:0140289	protein mono-ADP-ribosylation	2/988	12/18722	0.129408390745323	0.275849667591956	PARP14/PARP9	2
GO:1901503	ether biosynthetic process	2/988	12/18722	0.129408390745323	0.275849667591956	AGPS/FAR1	2
GO:1902950	regulation of dendritic spine maintenance	2/988	12/18722	0.129408390745323	0.275849667591956	FCGR2B/FYN	2
GO:1903909	regulation of receptor clustering	2/988	12/18722	0.129408390745323	0.275849667591956	CD81/GSN	2
GO:1904748	regulation of apoptotic process involved in development	2/988	12/18722	0.129408390745323	0.275849667591956	NOTCH1/TNFRSF1B	2
GO:1905245	regulation of aspartic-type peptidase activity	2/988	12/18722	0.129408390745323	0.275849667591956	PICALM/ROCK2	2
GO:1905709	negative regulation of membrane permeability	2/988	12/18722	0.129408390745323	0.275849667591956	HEG1/RASIP1	2
GO:2000009	negative regulation of protein localization to cell surface	2/988	12/18722	0.129408390745323	0.275849667591956	PICALM/LEPROT	2
GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	2/988	12/18722	0.129408390745323	0.275849667591956	TGFBR2/CD81	2
GO:0008016	regulation of heart contraction	15/988	206/18722	0.129524589675167	0.27598661065162	EDN1/CAV1/PDE4D/CLIC2/EPAS1/THRA/MEF2A/ADRB1/CALM1/GJA1/PDE4B/FLNA/ATP2B4/GJA5/ZMPSTE24	15
GO:0046850	regulation of bone remodeling	5/988	51/18722	0.130189885992994	0.276308850032206	LEPR/S1PR1/PDK4/MDK/LTBP3	5
GO:0050982	detection of mechanical stimulus	5/988	51/18722	0.130189885992994	0.276308850032206	ITGA2/PIEZO1/FYN/PKD2/PTK2	5
GO:0051293	establishment of spindle localization	5/988	51/18722	0.130189885992994	0.276308850032206	ITGB1/GJA1/MYH9/MAP4/DYNC1H1	5
GO:0099111	microtubule-based transport	14/988	190/18722	0.130399372937113	0.276308850032206	BICD1/DST/KIF5B/APP/ARMCX3/LAMP1/SUN1/HIF1A/PURA/PCM1/KIF1B/DYNC1H1/CDC42/KIFAP3	14
GO:0018196	peptidyl-asparagine modification	3/988	24/18722	0.130508076944805	0.276308850032206	ST6GAL1/MAGT1/RPN1	3
GO:0021801	cerebral cortex radial glia-guided migration	3/988	24/18722	0.130508076944805	0.276308850032206	SUN1/ZMIZ1/RTN4	3
GO:0022030	telencephalon glial cell migration	3/988	24/18722	0.130508076944805	0.276308850032206	SUN1/ZMIZ1/RTN4	3
GO:0033032	regulation of myeloid cell apoptotic process	3/988	24/18722	0.130508076944805	0.276308850032206	MEF2C/THRA/PTEN	3
GO:0035458	cellular response to interferon-beta	3/988	24/18722	0.130508076944805	0.276308850032206	IFITM2/IFI16/CAPN2	3
GO:0044062	regulation of excretion	3/988	24/18722	0.130508076944805	0.276308850032206	EDN1/NPR1/GNAI2	3
GO:0051000	positive regulation of nitric-oxide synthase activity	3/988	24/18722	0.130508076944805	0.276308850032206	SCARB1/CALM1/HIF1A	3
GO:0051043	regulation of membrane protein ectodomain proteolysis	3/988	24/18722	0.130508076944805	0.276308850032206	TIMP1/TNFRSF1B/ROCK1	3
GO:0051123	RNA polymerase II preinitiation complex assembly	3/988	24/18722	0.130508076944805	0.276308850032206	THRA/CREB1/ATF7IP	3
GO:0090023	positive regulation of neutrophil chemotaxis	3/988	24/18722	0.130508076944805	0.276308850032206	EDN1/MDK/MOSPD2	3
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	3/988	24/18722	0.130508076944805	0.276308850032206	CD36/RAB27A/CLCN3	3
GO:2000310	regulation of NMDA receptor activity	3/988	24/18722	0.130508076944805	0.276308850032206	CRHBP/MEF2C/APP	3
GO:0018393	internal peptidyl-lysine acetylation	12/988	158/18722	0.131020713704956	0.277283677769213	PCGF2/KMT2A/MSL1/OGT/GATA2/CLOCK/EID1/KAT6A/ATF2/SMAD4/ZMPSTE24/KANSL1	12
GO:0090596	sensory organ morphogenesis	18/988	256/18722	0.132152473316599	0.279567478398158	EDN1/JAG1/TSPAN12/TSHZ1/HIPK2/TUG1/ABI2/HIF1A/SKI/PTPRM/PHACTR4/STAT3/GATA2/FZD6/HIPK1/EFEMP1/NIPBL/MAPK1	18
GO:0009914	hormone transport	21/988	306/18722	0.132335983812332	0.27984424602353	EDN1/CRHBP/P2RY1/NNAT/FZD4/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CREB1/SNAP23/TBX3/CLOCK/PPP3CA/PIM3/SMAD2/MIDN/SMAD4/SLC16A2	21
GO:0050851	antigen receptor-mediated signaling pathway	17/988	240/18722	0.13393410957769	0.282991956594524	FCGR2B/CEACAM1/MEF2C/PDE4D/FOXP1/HLA-A/CD81/PRKCH/FYN/PIK3CA/PDE4B/CMTM3/RC3H1/CBLB/WNK1/MAPK1/BCL10	17
GO:0035270	endocrine system development	10/988	127/18722	0.134077041737991	0.282991956594524	ETS1/THRA/CDK6/MDK/CREB1/GATA2/CLOCK/SMAD2/HES1/MAPK1	10
GO:0001823	mesonephros development	8/988	96/18722	0.134140011641467	0.282991956594524	DCHS1/SMAD6/SMAD5/SMAD1/PKD2/SMAD2/HES1/SMAD4	8
GO:0044264	cellular polysaccharide metabolic process	8/988	96/18722	0.134140011641467	0.282991956594524	IGF1/LEPR/PCDH12/IGF2/IL6ST/RB1CC1/GBE1/B4GALT5	8
GO:0046626	regulation of insulin receptor signaling pathway	6/988	66/18722	0.134303976388328	0.282991956594524	GRB14/IGF2/GNAI2/SOCS3/OGT/PRKAA1	6
GO:0050766	positive regulation of phagocytosis	6/988	66/18722	0.134303976388328	0.282991956594524	FCGR2B/ITGA2/CD36/RAB27A/GATA2/RAP1A	6
GO:0050922	negative regulation of chemotaxis	6/988	66/18722	0.134303976388328	0.282991956594524	ANGPT2/THBS1/NOTCH1/NRP1/DUSP1/SEMA3F	6
GO:0071300	cellular response to retinoic acid	6/988	66/18722	0.134303976388328	0.282991956594524	FZD4/YES1/KLF4/SETX/CREB1/ABCA1	6
GO:2000573	positive regulation of DNA biosynthetic process	6/988	66/18722	0.134303976388328	0.282991956594524	RGCC/PDGFB/HMBOX1/KLF4/NEK7/MAPK1	6
GO:0031023	microtubule organizing center organization	11/988	143/18722	0.135094136698628	0.28432678554679	MPDZ/CEP68/PCM1/PKD2/PDCD6IP/ROCK2/XPO1/PLK2/CHD3/PPP1R12A/NIN	11
GO:0070555	response to interleukin-1	11/988	143/18722	0.135094136698628	0.28432678554679	EDN1/HYAL2/TFPI/IL1R1/ETS1/PLCB1/KLF2/APP/HIF1A/EGR1/RC3H1	11
GO:0001960	negative regulation of cytokine-mediated signaling pathway	7/988	81/18722	0.135151568807539	0.28432678554679	CAV1/SH2B3/CARD16/CARD8/PARP14/ISG15/ADAR	7
GO:0044773	mitotic DNA damage checkpoint signaling	7/988	81/18722	0.135151568807539	0.28432678554679	PML/TAOK1/CCND1/WAC/ATF2/FOXN3/PLK2	7
GO:0046488	phosphatidylinositol metabolic process	12/988	159/18722	0.135352313849972	0.284636378135808	PLCB1/PIK3R3/PDGFB/SOCS3/LPGAT1/PIK3CA/PIK3C2B/PTEN/MTMR6/PIK3C2A/SOCS4/SMG1	12
GO:0005996	monosaccharide metabolic process	18/988	257/18722	0.135528204998297	0.284893480392145	IGFBP4/IGF1/NNMT/LEPR/FABP5/IGF2/PDK4/CPT1A/PIK3CA/KBTBD2/RANBP2/OGT/ARPP19/SLC2A1/PRKAA1/SLC2A3/MIDN/ZMPSTE24	18
GO:0032984	protein-containing complex disassembly	16/988	224/18722	0.135582242864851	0.284894333108422	SPTBN1/SPTAN1/KIF5B/CALM1/TAOK1/PIK3CA/TMOD3/SETX/RDX/ADD1/APC/GSN/ARID1A/DSTN/CAMSAP2/ZMPSTE24	16
GO:0002526	acute inflammatory response	9/988	112/18722	0.137283317790906	0.288354679361522	FCGR2B/FN1/PRCP/HLA-E/OSMR/IL6ST/STAT3/PLSCR1/ASH1L	9
GO:0010662	regulation of striated muscle cell apoptotic process	5/988	52/18722	0.138188937058972	0.289301792151733	MDK/CFLAR/RGL2/PTEN/CAPN2	5
GO:0032206	positive regulation of telomere maintenance	5/988	52/18722	0.138188937058972	0.289301792151733	PML/ATRX/HMBOX1/NEK7/MAPK1	5
GO:0045010	actin nucleation	5/988	52/18722	0.138188937058972	0.289301792151733	NCKAP1/ACTR2/ABI2/GSN/WASL	5
GO:0072523	purine-containing compound catabolic process	5/988	52/18722	0.138188937058972	0.289301792151733	NT5E/PDE4D/NUDT3/PDE4B/ACAT1	5
GO:2000378	negative regulation of reactive oxygen species metabolic process	5/988	52/18722	0.138188937058972	0.289301792151733	CFLAR/FYN/RHOA/HIF1A/STAT3	5
GO:0000578	embryonic axis specification	4/988	38/18722	0.138660083361881	0.289301792151733	SMAD6/TBX3/SMAD2/SMAD4	4
GO:0009595	detection of biotic stimulus	4/988	38/18722	0.138660083361881	0.289301792151733	DACH1/SCARB1/HLA-A/HLA-B	4
GO:0010742	macrophage derived foam cell differentiation	4/988	38/18722	0.138660083361881	0.289301792151733	PRKCH/TGFB1/CD36/ABCA1	4
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	4/988	38/18722	0.138660083361881	0.289301792151733	FOXP1/RHOA/CLOCK/CNOT2	4
GO:0035136	forelimb morphogenesis	4/988	38/18722	0.138660083361881	0.289301792151733	HOXA13/ATRX/TBX3/NIPBL	4
GO:0035337	fatty-acyl-CoA metabolic process	4/988	38/18722	0.138660083361881	0.289301792151733	ACSL3/ELOVL5/HSD17B12/FAR1	4
GO:0042596	fear response	4/988	38/18722	0.138660083361881	0.289301792151733	MEF2C/MDK/ADRB1/GJA1	4
GO:0046676	negative regulation of insulin secretion	4/988	38/18722	0.138660083361881	0.289301792151733	MAP4K4/PPP3CA/PIM3/MIDN	4
GO:0048713	regulation of oligodendrocyte differentiation	4/988	38/18722	0.138660083361881	0.289301792151733	NOTCH1/MDK/TNFRSF1B/HES1	4
GO:0071392	cellular response to estradiol stimulus	4/988	38/18722	0.138660083361881	0.289301792151733	CRHBP/RAMP3/ITGA2/CFLAR	4
GO:0090077	foam cell differentiation	4/988	38/18722	0.138660083361881	0.289301792151733	PRKCH/TGFB1/CD36/ABCA1	4
GO:1901186	positive regulation of ERBB signaling pathway	4/988	38/18722	0.138660083361881	0.289301792151733	HIP1/RTN4/CCDC88A/SOS1	4
GO:0010821	regulation of mitochondrion organization	11/988	144/18722	0.139754044174873	0.29125594845142	KDR/IGF1/TNFSF10/VAT1/CLU/DDHD1/HIF1A/CTTN/VPS13C/RALA/HSPA1A	11
GO:0031644	regulation of nervous system process	11/988	144/18722	0.139754044174873	0.29125594845142	EDN1/JAM2/ITGA2/F2R/FABP5/APP/DICER1/PTEN/TNFRSF1B/DLGAP4/ROCK2	11
GO:0006475	internal protein amino acid acetylation	12/988	160/18722	0.139761184601406	0.29125594845142	PCGF2/KMT2A/MSL1/OGT/GATA2/CLOCK/EID1/KAT6A/ATF2/SMAD4/ZMPSTE24/KANSL1	12
GO:1990868	response to chemokine	8/988	97/18722	0.139890748926889	0.291297396432628	EDN1/SH2B3/SLC12A2/DUSP1/RHOA/HIF1A/LRCH1/WNK1	8
GO:1990869	cellular response to chemokine	8/988	97/18722	0.139890748926889	0.291297396432628	EDN1/SH2B3/SLC12A2/DUSP1/RHOA/HIF1A/LRCH1/WNK1	8
GO:0006513	protein monoubiquitination	6/988	67/18722	0.14137066186042	0.293593236692562	PCGF2/BCOR/RYBP/PCGF5/WAC/DTX3L	6
GO:0043967	histone H4 acetylation	6/988	67/18722	0.14137066186042	0.293593236692562	KMT2A/MSL1/OGT/ATF2/ZMPSTE24/KANSL1	6
GO:0061077	chaperone-mediated protein folding	6/988	67/18722	0.14137066186042	0.293593236692562	FKBP1A/CLU/ERO1A/CRTAP/HSPA1A/HSPH1	6
GO:0002312	B cell activation involved in immune response	7/988	82/18722	0.141490716478343	0.293593236692562	FCGR2B/ITM2A/MFNG/LGALS1/TGFB1/KMT5B/RIF1	7
GO:0007032	endosome organization	7/988	82/18722	0.141490716478343	0.293593236692562	TMCC1/SCARB2/RAB27A/PDCD6IP/RAB11A/CLCN3/VPS36	7
GO:0008543	fibroblast growth factor receptor signaling pathway	7/988	82/18722	0.141490716478343	0.293593236692562	KL/FGFR1/THBS1/SULF2/SETX/NPTN/SHOC2	7
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	7/988	82/18722	0.141490716478343	0.293593236692562	THBS1/SKIL/PEA15/CFLAR/PTEN/FEM1B/SP100	7
GO:0016575	histone deacetylation	7/988	82/18722	0.141490716478343	0.293593236692562	APLNR/HDAC7/ELK4/SKI/TBL1XR1/NIPBL/BAZ2A	7
GO:2001252	positive regulation of chromosome organization	7/988	82/18722	0.141490716478343	0.293593236692562	PML/ATRX/HMBOX1/SLF2/ATF7IP/NEK7/MAPK1	7
GO:0006753	nucleoside phosphate metabolic process	32/988	497/18722	0.142443036455636	0.29381351256916	IGF1/NNMT/IDO1/PAPSS2/NT5E/ADCY4/ZBTB20/NPR1/PDE4D/GIMAP7/TMSB4X/ENTPD1/GIT1/PDK4/APP/TGFB1/NUDT3/ACSL3/PDE4B/ELOVL5/RHOA/HIF1A/HSD17B12/OGT/STAT3/ATP6V1A/ACAT1/PARP9/PRKAA1/DIP2A/MAPK1/FAR1	32
GO:0071347	cellular response to interleukin-1	9/988	113/18722	0.142651699900698	0.29381351256916	EDN1/HYAL2/TFPI/IL1R1/PLCB1/KLF2/HIF1A/EGR1/RC3H1	9
GO:0010560	positive regulation of glycoprotein biosynthetic process	3/988	25/18722	0.142813721659181	0.29381351256916	IGF1/IL33/PLCB1	3
GO:0010954	positive regulation of protein processing	3/988	25/18722	0.142813721659181	0.29381351256916	CLEC3B/MYH9/GSN	3
GO:0032925	regulation of activin receptor signaling pathway	3/988	25/18722	0.142813721659181	0.29381351256916	FKBP1A/SKI/SMAD2	3
GO:0033233	regulation of protein sumoylation	3/988	25/18722	0.142813721659181	0.29381351256916	ZMIZ1/EGR1/PIAS1	3
GO:0042730	fibrinolysis	3/988	25/18722	0.142813721659181	0.29381351256916	PROS1/THBD/THBS1	3
GO:0046949	fatty-acyl-CoA biosynthetic process	3/988	25/18722	0.142813721659181	0.29381351256916	ACSL3/ELOVL5/HSD17B12	3
GO:0048596	embryonic camera-type eye morphogenesis	3/988	25/18722	0.142813721659181	0.29381351256916	HIPK2/PHACTR4/HIPK1	3
GO:0051450	myoblast proliferation	3/988	25/18722	0.142813721659181	0.29381351256916	IGF1/MALAT1/ATF2	3
GO:0060074	synapse maturation	3/988	25/18722	0.142813721659181	0.29381351256916	NFIA/ARHGEF15/PTEN	3
GO:0060706	cell differentiation involved in embryonic placenta development	3/988	25/18722	0.142813721659181	0.29381351256916	SOCS3/NR2F2/HECTD1	3
GO:0060740	prostate gland epithelium morphogenesis	3/988	25/18722	0.142813721659181	0.29381351256916	HOXA13/NOTCH1/FEM1B	3
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	3/988	25/18722	0.142813721659181	0.29381351256916	XIAP/CYLD/HSPA1A	3
GO:0090169	regulation of spindle assembly	3/988	25/18722	0.142813721659181	0.29381351256916	DYNC1H1/HSPA1A/SENP6	3
GO:0098581	detection of external biotic stimulus	3/988	25/18722	0.142813721659181	0.29381351256916	SCARB1/HLA-A/HLA-B	3
GO:0098703	calcium ion import across plasma membrane	3/988	25/18722	0.142813721659181	0.29381351256916	RAMP3/FYN/ATP2B4	3
GO:1900078	positive regulation of cellular response to insulin stimulus	3/988	25/18722	0.142813721659181	0.29381351256916	IGF2/GNAI2/MYO1C	3
GO:1902993	positive regulation of amyloid precursor protein catabolic process	3/988	25/18722	0.142813721659181	0.29381351256916	CLU/PICALM/ROCK2	3
GO:1904385	cellular response to angiotensin	3/988	25/18722	0.142813721659181	0.29381351256916	CAV1/ROCK2/ROCK1	3
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	3/988	25/18722	0.142813721659181	0.29381351256916	DOCK4/PDGFB/IQGAP1	3
GO:1905048	regulation of metallopeptidase activity	3/988	25/18722	0.142813721659181	0.29381351256916	TIMP1/STAT3/PICALM	3
GO:0098739	import across plasma membrane	13/988	177/18722	0.143483404867837	0.29507698283312	RAMP3/LRRC8C/THBS1/ITGB1/SLC12A2/FYN/CD36/SLC30A1/SLC2A1/ATP2B4/SLC2A3/WNK1/SLC16A2	13
GO:0007269	neurotransmitter secretion	11/988	145/18722	0.144498357595847	0.296934342572201	P2RY1/MEF2C/SYT11/GIT1/CALM1/STX3/SLC30A1/SNAP23/CTBP2/RAB5A/RAP1A	11
GO:0099643	signal release from synapse	11/988	145/18722	0.144498357595847	0.296934342572201	P2RY1/MEF2C/SYT11/GIT1/CALM1/STX3/SLC30A1/SNAP23/CTBP2/RAB5A/RAP1A	11
GO:0070301	cellular response to hydrogen peroxide	8/988	98/18722	0.145762641939222	0.299416532862005	FOXO1/ETS1/KLF2/RHOB/PCGF2/KLF4/SETX/PRKAA1	8
GO:0008347	glial cell migration	5/988	53/18722	0.146398318466986	0.300038977852012	P2RY1/SUN1/ZMIZ1/RTN4/CD9	5
GO:0001768	establishment of T cell polarity	2/988	13/18722	0.147816642514818	0.300038977852012	MYH9/GSN	2
GO:0001973	G protein-coupled adenosine receptor signaling pathway	2/988	13/18722	0.147816642514818	0.300038977852012	P2RY1/GNAI2	2
GO:0002638	negative regulation of immunoglobulin production	2/988	13/18722	0.147816642514818	0.300038977852012	FCGR2B/TMBIM6	2
GO:0009134	nucleoside diphosphate catabolic process	2/988	13/18722	0.147816642514818	0.300038977852012	NT5E/ENTPD1	2
GO:0010755	regulation of plasminogen activation	2/988	13/18722	0.147816642514818	0.300038977852012	CLEC3B/THBS1	2
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	2/988	13/18722	0.147816642514818	0.300038977852012	CARD16/CARD8	2
GO:0032230	positive regulation of synaptic transmission, GABAergic	2/988	13/18722	0.147816642514818	0.300038977852012	PRKCE/KIF5B	2
GO:0032352	positive regulation of hormone metabolic process	2/988	13/18722	0.147816642514818	0.300038977852012	HIF1A/EGR1	2
GO:0032530	regulation of microvillus organization	2/988	13/18722	0.147816642514818	0.300038977852012	PODXL/FSCN1	2
GO:0035331	negative regulation of hippo signaling	2/988	13/18722	0.147816642514818	0.300038977852012	WWC2/WWC3	2
GO:0035588	G protein-coupled purinergic receptor signaling pathway	2/988	13/18722	0.147816642514818	0.300038977852012	P2RY1/GNAI2	2
GO:0042541	hemoglobin biosynthetic process	2/988	13/18722	0.147816642514818	0.300038977852012	KLF4/HIF1A	2
GO:0043970	histone H3-K9 acetylation	2/988	13/18722	0.147816642514818	0.300038977852012	KMT2A/SMAD4	2
GO:0044090	positive regulation of vacuole organization	2/988	13/18722	0.147816642514818	0.300038977852012	RALB/SH3GLB1	2
GO:0044794	positive regulation by host of viral process	2/988	13/18722	0.147816642514818	0.300038977852012	CAV2/STOM	2
GO:0046642	negative regulation of alpha-beta T cell proliferation	2/988	13/18722	0.147816642514818	0.300038977852012	TNFRSF14/CBLB	2
GO:0048266	behavioral response to pain	2/988	13/18722	0.147816642514818	0.300038977852012	THBS1/CAPN2	2
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2/988	13/18722	0.147816642514818	0.300038977852012	APC/CDC42	2
GO:0060670	branching involved in labyrinthine layer morphogenesis	2/988	13/18722	0.147816642514818	0.300038977852012	RSPO3/SOCS3	2
GO:0061000	negative regulation of dendritic spine development	2/988	13/18722	0.147816642514818	0.300038977852012	PTEN/PLK2	2
GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	2/988	13/18722	0.147816642514818	0.300038977852012	XIAP/HSPA1A	2
GO:0071696	ectodermal placode development	2/988	13/18722	0.147816642514818	0.300038977852012	NRP1/TBX3	2
GO:1900044	regulation of protein K63-linked ubiquitination	2/988	13/18722	0.147816642514818	0.300038977852012	SASH1/TRIP12	2
GO:1900115	extracellular regulation of signal transduction	2/988	13/18722	0.147816642514818	0.300038977852012	LTBP1/CD46	2
GO:1900116	extracellular negative regulation of signal transduction	2/988	13/18722	0.147816642514818	0.300038977852012	LTBP1/CD46	2
GO:1900121	negative regulation of receptor binding	2/988	13/18722	0.147816642514818	0.300038977852012	ADAM15/B2M	2
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	2/988	13/18722	0.147816642514818	0.300038977852012	TMSB4X/ZMPSTE24	2
GO:1903651	positive regulation of cytoplasmic transport	2/988	13/18722	0.147816642514818	0.300038977852012	MSN/RDX	2
GO:1905244	regulation of modification of synaptic structure	2/988	13/18722	0.147816642514818	0.300038977852012	RHOA/CDC42	2
GO:2001198	regulation of dendritic cell differentiation	2/988	13/18722	0.147816642514818	0.300038977852012	FCGR2B/HLA-B	2
GO:0046785	microtubule polymerization	7/988	83/18722	0.147970363188118	0.300102643712949	CDH5/GIT1/ARHGEF7/DYRK1A/HSPA1A/CAMSAP2/NIN	7
GO:0050672	negative regulation of lymphocyte proliferation	7/988	83/18722	0.147970363188118	0.300102643712949	FCGR2B/LRRC32/PKN1/PRKAR1A/TNFRSF14/RC3H1/CBLB	7
GO:1904892	regulation of receptor signaling pathway via STAT	9/988	114/18722	0.148125158547337	0.300102643712949	F2R/CAV1/NOTCH1/SH2B3/SOCS3/TGFB1/PARP14/LEPROT/HES1	9
GO:0007618	mating	4/988	39/18722	0.148469455511602	0.300102643712949	P2RY1/THRA/APP/PTEN	4
GO:0010463	mesenchymal cell proliferation	4/988	39/18722	0.148469455511602	0.300102643712949	NFIB/FOXF1/DCHS1/TGFBR2	4
GO:0032506	cytokinetic process	4/988	39/18722	0.148469455511602	0.300102643712949	MYH9/RHOA/PLEC/PDCD6IP	4
GO:0034314	Arp2/3 complex-mediated actin nucleation	4/988	39/18722	0.148469455511602	0.300102643712949	NCKAP1/ACTR2/ABI2/WASL	4
GO:0046326	positive regulation of glucose import	4/988	39/18722	0.148469455511602	0.300102643712949	IGF1/MEF2A/ARPP19/RAP1A	4
GO:0071548	response to dexamethasone	4/988	39/18722	0.148469455511602	0.300102643712949	EDN1/FOXO1/CFLAR/NR3C1	4
GO:1903115	regulation of actin filament-based movement	4/988	39/18722	0.148469455511602	0.300102643712949	CAV1/PDE4D/PDE4B/GJA5	4
GO:2000785	regulation of autophagosome assembly	4/988	39/18722	0.148469455511602	0.300102643712949	FEZ2/RALB/SH3GLB1/RAB5A	4
GO:0051926	negative regulation of calcium ion transport	6/988	68/18722	0.148605251451843	0.300262873987139	CLIC2/CALM1/SESTD1/TMBIM6/SLC30A1/PKD2	6
GO:0007098	centrosome cycle	10/988	130/18722	0.149184254173838	0.301318159000543	CEP68/PCM1/PKD2/PDCD6IP/ROCK2/XPO1/PLK2/CHD3/PPP1R12A/NIN	10
GO:0046879	hormone secretion	20/988	295/18722	0.151025465807847	0.304921046891403	EDN1/CRHBP/P2RY1/NNAT/FZD4/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CREB1/SNAP23/TBX3/CLOCK/PPP3CA/PIM3/SMAD2/MIDN/SMAD4	20
GO:0006165	nucleoside diphosphate phosphorylation	8/988	99/18722	0.1517534706645	0.30627448182744	IGF1/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	8
GO:0006457	protein folding	15/988	212/18722	0.152830269053597	0.308330569393356	FKBP1A/CLU/B2M/FKBP9/CANX/DNAJC10/QSOX1/ERO1A/RANBP2/HSP90B1/NKTR/ATF6/CRTAP/HSPA1A/HSPH1	15
GO:0050657	nucleic acid transport	12/988	163/18722	0.153443948603483	0.309333683105009	HHEX/TGFBR2/ZFP36L1/RANBP2/QKI/ZFP36/ZC3H11A/MYO1C/FYTTD1/THOC2/SMG1/XPO1	12
GO:0050658	RNA transport	12/988	163/18722	0.153443948603483	0.309333683105009	HHEX/TGFBR2/ZFP36L1/RANBP2/QKI/ZFP36/ZC3H11A/MYO1C/FYTTD1/THOC2/SMG1/XPO1	12
GO:0000077	DNA damage checkpoint signaling	9/988	115/18722	0.15370200654683	0.309736365241562	PML/TAOK1/FEM1B/CLOCK/CCND1/WAC/ATF2/FOXN3/PLK2	9
GO:1902850	microtubule cytoskeleton organization involved in mitosis	11/988	147/18722	0.154236252962626	0.310035678482243	ITGB1/GJA1/FLNA/RHOA/TACC1/STAG2/MAP4/RAB11A/DYNC1H1/HSPA1A/PLK2	11
GO:0006612	protein targeting to membrane	10/988	131/18722	0.154404968023354	0.310035678482243	STOM/TRAM1/FYN/SEC62/GDI1/SDCBP/MYO1C/CHM/SEC61A1/GOLGA7	10
GO:0006661	phosphatidylinositol biosynthetic process	10/988	131/18722	0.154404968023354	0.310035678482243	PIK3R3/PDGFB/SOCS3/PIK3CA/PIK3C2B/PTEN/MTMR6/PIK3C2A/SOCS4/SMG1	10
GO:0032508	DNA duplex unwinding	7/988	84/18722	0.154587309315531	0.310035678482243	CHD9/ATRX/SETX/PURA/RECQL/G3BP1/CHD3	7
GO:0032945	negative regulation of mononuclear cell proliferation	7/988	84/18722	0.154587309315531	0.310035678482243	FCGR2B/LRRC32/PKN1/PRKAR1A/TNFRSF14/RC3H1/CBLB	7
GO:0098586	cellular response to virus	7/988	84/18722	0.154587309315531	0.310035678482243	SEC14L1/DDX60/TSPAN6/HIF1A/ADAR/ATF2/PUM2	7
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5/988	54/18722	0.154810309247132	0.310035678482243	FCGR2B/CEACAM1/AHR/RC3H1/CD46	5
GO:0006968	cellular defense response	5/988	54/18722	0.154810309247132	0.310035678482243	IL33/ITGB1/VEZF1/ZNF148/BCL10	5
GO:0014888	striated muscle adaptation	5/988	54/18722	0.154810309247132	0.310035678482243	FOXO1/CFLAR/ATP2B4/PPP3CA/GSN	5
GO:0032330	regulation of chondrocyte differentiation	5/988	54/18722	0.154810309247132	0.310035678482243	ACVRL1/LOXL2/MDK/EFEMP1/LTBP3	5
GO:0035065	regulation of histone acetylation	5/988	54/18722	0.154810309247132	0.310035678482243	KMT2A/GATA2/EID1/SMAD4/ZMPSTE24	5
GO:2000300	regulation of synaptic vesicle exocytosis	5/988	54/18722	0.154810309247132	0.310035678482243	P2RY1/GIT1/CALM1/RAB5A/RAP1A	5
GO:0002026	regulation of the force of heart contraction	3/988	26/18722	0.155484760443655	0.310035678482243	CAV1/ADRB1/ATP2B4	3
GO:0002710	negative regulation of T cell mediated immunity	3/988	26/18722	0.155484760443655	0.310035678482243	FCGR2B/CEACAM1/AHR	3
GO:0006517	protein deglycosylation	3/988	26/18722	0.155484760443655	0.310035678482243	EDEM3/MAN1A1/TRIM13	3
GO:0009435	NAD biosynthetic process	3/988	26/18722	0.155484760443655	0.310035678482243	NNMT/IDO1/PARP9	3
GO:0018027	peptidyl-lysine dimethylation	3/988	26/18722	0.155484760443655	0.310035678482243	KMT2A/ASH1L/KMT5B	3
GO:0034114	regulation of heterotypic cell-cell adhesion	3/988	26/18722	0.155484760443655	0.310035678482243	KLF4/CD44/WNK1	3
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	3/988	26/18722	0.155484760443655	0.310035678482243	XIAP/CYLD/HSPA1A	3
GO:0042634	regulation of hair cycle	3/988	26/18722	0.155484760443655	0.310035678482243	CLOCK/NIPBL/SMAD4	3
GO:0046697	decidualization	3/988	26/18722	0.155484760443655	0.310035678482243	GJA1/ASH1L/MAPK1	3
GO:0051016	barbed-end actin filament capping	3/988	26/18722	0.155484760443655	0.310035678482243	RDX/ADD1/GSN	3
GO:0060352	cell adhesion molecule production	3/988	26/18722	0.155484760443655	0.310035678482243	NOTCH4/CAV1/NOTCH1	3
GO:0070977	bone maturation	3/988	26/18722	0.155484760443655	0.310035678482243	IGF1/DCHS1/RHOA	3
GO:0099637	neurotransmitter receptor transport	3/988	26/18722	0.155484760443655	0.310035678482243	HIP1/STX3/RAB11A	3
GO:1902186	regulation of viral release from host cell	3/988	26/18722	0.155484760443655	0.310035678482243	CAV2/PML/TRIM13	3
GO:1902656	calcium ion import into cytosol	3/988	26/18722	0.155484760443655	0.310035678482243	RAMP3/FYN/ATP2B4	3
GO:2000108	positive regulation of leukocyte apoptotic process	3/988	26/18722	0.155484760443655	0.310035678482243	IDO1/MEF2C/RAPGEF2	3
GO:0031668	cellular response to extracellular stimulus	17/988	246/18722	0.15584698945213	0.31064135383479	NUAK1/BMPR2/FOXO1/SLC38A2/IFI16/PDK4/RALB/EIF2AK2/SLC2A1/PRKAA1/XPR1/PLEC/KLF10/SH3GLB1/TNRC6A/MAPK1/JUN	17
GO:0050805	negative regulation of synaptic transmission	6/988	69/18722	0.15600293914609	0.310835563669928	SYT11/GNAI2/PTEN/SLC30A1/PLK2/RAP1A	6
GO:0072521	purine-containing compound metabolic process	27/988	416/18722	0.156409856821222	0.311529493601174	IGF1/PAPSS2/NT5E/ADCY4/ZBTB20/NPR1/PDE4D/GIMAP7/TMSB4X/GIT1/PDK4/APP/TGFB1/NUDT3/ACSL3/PDE4B/ELOVL5/RHOA/HIF1A/HSD17B12/OGT/STAT3/ATP6V1A/ACAT1/PRKAA1/DIP2A/FAR1	27
GO:0043583	ear development	15/988	213/18722	0.156920943513541	0.31243030432681	SPARC/EDN1/ECE1/HOXA13/TCF15/DCHS1/JAG1/TSHZ1/NOTCH1/ADAM10/GATA2/FZD6/NIPBL/HES1/MAPK1	15
GO:0002714	positive regulation of B cell mediated immunity	4/988	40/18722	0.158536579857322	0.314821051290503	HLA-E/TGFB1/KMT5B/RIF1	4
GO:0002891	positive regulation of immunoglobulin mediated immune response	4/988	40/18722	0.158536579857322	0.314821051290503	HLA-E/TGFB1/KMT5B/RIF1	4
GO:0009187	cyclic nucleotide metabolic process	4/988	40/18722	0.158536579857322	0.314821051290503	ADCY4/NPR1/PDE4D/PDE4B	4
GO:0045740	positive regulation of DNA replication	4/988	40/18722	0.158536579857322	0.314821051290503	ATRX/TNFAIP1/CDC42/JUN	4
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	4/988	40/18722	0.158536579857322	0.314821051290503	APLNR/F2R/CALM1/PKD2	4
GO:0070266	necroptotic process	4/988	40/18722	0.158536579857322	0.314821051290503	CAV1/CFLAR/OGT/CYLD	4
GO:1901998	toxin transport	4/988	40/18722	0.158536579857322	0.314821051290503	LRP6/NRP1/ANTXR2/ADAM10	4
GO:0008380	RNA splicing	28/988	434/18722	0.158642067702131	0.314912804048476	NOVA2/SLC38A2/DDX17/PABPC1/MBNL1/SETX/QKI/TMBIM6/AHNAK/CELF1/SON/ZNF638/MBNL2/SF3B1/THOC2/LUC7L3/PTBP3/RBM5/SREK1IP1/DYRK1A/SCAF11/HNRNPH1/HNRNPK/HSPA1A/TIA1/RBM12/PSIP1/SRSF11	28
GO:0044272	sulfur compound biosynthetic process	11/988	148/18722	0.159227691033403	0.31583924375259	PAPSS2/ANGPT1/MGST2/PDK4/MRI1/CHSY1/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A	11
GO:0097530	granulocyte migration	11/988	148/18722	0.159227691033403	0.31583924375259	PECAM1/EDN1/ITGA1/IL1R1/THBS1/MDK/JAM3/PDE4B/MOSPD2/PTK2/MAPK1	11
GO:0030326	embryonic limb morphogenesis	9/988	116/18722	0.159380453258187	0.315906331234138	ECE1/HOXA13/NOTCH1/MBNL1/SKI/TBX3/FZD6/NIPBL/SMAD4	9
GO:0035113	embryonic appendage morphogenesis	9/988	116/18722	0.159380453258187	0.315906331234138	ECE1/HOXA13/NOTCH1/MBNL1/SKI/TBX3/FZD6/NIPBL/SMAD4	9
GO:0044774	mitotic DNA integrity checkpoint signaling	7/988	85/18722	0.161338181597981	0.319548255275345	PML/TAOK1/CCND1/WAC/ATF2/FOXN3/PLK2	7
GO:0055072	iron ion homeostasis	7/988	85/18722	0.161338181597981	0.319548255275345	HYAL2/EPAS1/B2M/HIF1A/ATP6V1A/PICALM/SMAD4	7
GO:0032635	interleukin-6 production	12/988	165/18722	0.162937458973074	0.322475328638214	IL33/F2R/HYAL2/SYT11/KLF2/HLA-B/APP/CD200/CAPN2/CD36/STAT3/BCL10	12
GO:0032675	regulation of interleukin-6 production	12/988	165/18722	0.162937458973074	0.322475328638214	IL33/F2R/HYAL2/SYT11/KLF2/HLA-B/APP/CD200/CAPN2/CD36/STAT3/BCL10	12
GO:0098900	regulation of action potential	5/988	55/18722	0.163416873501612	0.32330369908401	CAV1/CALM1/FLNA/CD36/GJA5	5
GO:0046939	nucleotide phosphorylation	8/988	101/18722	0.16408238767067	0.324499494901936	IGF1/ZBTB20/GIT1/APP/HIF1A/OGT/STAT3/PRKAA1	8
GO:0051225	spindle assembly	9/988	117/18722	0.165158608105193	0.324854170232558	CCDC69/FLNA/RHOA/STAG2/NEK7/RAB11A/DYNC1H1/HSPA1A/SENP6	9
GO:0009260	ribonucleotide biosynthetic process	13/988	182/18722	0.165779783648399	0.324854170232558	PAPSS2/ADCY4/NPR1/TMSB4X/PDK4/TGFB1/ACSL3/ELOVL5/HSD17B12/STAT3/ATP6V1A/ACAT1/DIP2A	13
GO:0000212	meiotic spindle organization	2/988	14/18722	0.166707919437868	0.324854170232558	ATRX/MYH9	2
GO:0001767	establishment of lymphocyte polarity	2/988	14/18722	0.166707919437868	0.324854170232558	MYH9/GSN	2
GO:0001771	immunological synapse formation	2/988	14/18722	0.166707919437868	0.324854170232558	MSN/CD81	2
GO:0001921	positive regulation of receptor recycling	2/988	14/18722	0.166707919437868	0.324854170232558	RAMP3/ECE1	2
GO:0002475	antigen processing and presentation via MHC class Ib	2/988	14/18722	0.166707919437868	0.324854170232558	HLA-E/B2M	2
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2/988	14/18722	0.166707919437868	0.324854170232558	FCGR2B/HLA-E	2
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	2/988	14/18722	0.166707919437868	0.324854170232558	TGFBR2/SERPINH1	2
GO:0006465	signal peptide processing	2/988	14/18722	0.166707919437868	0.324854170232558	PCSK5/SPCS3	2
GO:0006596	polyamine biosynthetic process	2/988	14/18722	0.166707919437868	0.324854170232558	NNMT/OAZ2	2
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	2/988	14/18722	0.166707919437868	0.324854170232558	SOCS4/CBLB	2
GO:0009214	cyclic nucleotide catabolic process	2/988	14/18722	0.166707919437868	0.324854170232558	PDE4D/PDE4B	2
GO:0010457	centriole-centriole cohesion	2/988	14/18722	0.166707919437868	0.324854170232558	CEP68/NIN	2
GO:0018158	protein oxidation	2/988	14/18722	0.166707919437868	0.324854170232558	LOXL2/TMX3	2
GO:0030213	hyaluronan biosynthetic process	2/988	14/18722	0.166707919437868	0.324854170232558	PDGFB/TGFB1	2
GO:0031054	pre-miRNA processing	2/988	14/18722	0.166707919437868	0.324854170232558	DICER1/ADAR	2
GO:0033169	histone H3-K9 demethylation	2/988	14/18722	0.166707919437868	0.324854170232558	KDM7A/JMJD1C	2
GO:0033604	negative regulation of catecholamine secretion	2/988	14/18722	0.166707919437868	0.324854170232558	P2RY1/SYT11	2
GO:0035641	locomotory exploration behavior	2/988	14/18722	0.166707919437868	0.324854170232558	PRKCE/CRBN	2
GO:0043249	erythrocyte maturation	2/988	14/18722	0.166707919437868	0.324854170232558	KLF2/PTBP3	2
GO:0043951	negative regulation of cAMP-mediated signaling	2/988	14/18722	0.166707919437868	0.324854170232558	APLNR/PDE4D	2
GO:0045820	negative regulation of glycolytic process	2/988	14/18722	0.166707919437868	0.324854170232558	GIT1/STAT3	2
GO:0048368	lateral mesoderm development	2/988	14/18722	0.166707919437868	0.324854170232558	FOXF1/SMAD2	2
GO:0048875	chemical homeostasis within a tissue	2/988	14/18722	0.166707919437868	0.324854170232558	ADGRF5/EPAS1	2
GO:0050872	white fat cell differentiation	2/988	14/18722	0.166707919437868	0.324854170232558	FABP4/CTBP2	2
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	2/988	14/18722	0.166707919437868	0.324854170232558	ITGA2/FYN	2
GO:0051547	regulation of keratinocyte migration	2/988	14/18722	0.166707919437868	0.324854170232558	PTEN/MAP4K4	2
GO:0051764	actin crosslink formation	2/988	14/18722	0.166707919437868	0.324854170232558	MARCKS/FLNA	2
GO:0051917	regulation of fibrinolysis	2/988	14/18722	0.166707919437868	0.324854170232558	THBD/THBS1	2
GO:0060354	negative regulation of cell adhesion molecule production	2/988	14/18722	0.166707919437868	0.324854170232558	NOTCH4/NOTCH1	2
GO:0060576	intestinal epithelial cell development	2/988	14/18722	0.166707919437868	0.324854170232558	IL6ST/HIF1A	2
GO:0070141	response to UV-A	2/988	14/18722	0.166707919437868	0.324854170232558	TIMP1/CCND1	2
GO:0070307	lens fiber cell development	2/988	14/18722	0.166707919437868	0.324854170232558	VIM/ABI2	2
GO:0071236	cellular response to antibiotic	2/988	14/18722	0.166707919437868	0.324854170232558	MEF2C/ACTR2	2
GO:1901077	regulation of relaxation of muscle	2/988	14/18722	0.166707919437868	0.324854170232558	PDE4D/PDE4B	2
GO:1902187	negative regulation of viral release from host cell	2/988	14/18722	0.166707919437868	0.324854170232558	PML/TRIM13	2
GO:1904294	positive regulation of ERAD pathway	2/988	14/18722	0.166707919437868	0.324854170232558	CAV1/ATXN3	2
GO:1905049	negative regulation of metallopeptidase activity	2/988	14/18722	0.166707919437868	0.324854170232558	TIMP1/PICALM	2
GO:2001171	positive regulation of ATP biosynthetic process	2/988	14/18722	0.166707919437868	0.324854170232558	TMSB4X/STAT3	2
GO:0009117	nucleotide metabolic process	31/988	489/18722	0.167185359173612	0.325204412950756	IGF1/NNMT/IDO1/PAPSS2/NT5E/ADCY4/ZBTB20/NPR1/PDE4D/GIMAP7/TMSB4X/GIT1/PDK4/APP/TGFB1/NUDT3/ACSL3/PDE4B/ELOVL5/RHOA/HIF1A/HSD17B12/OGT/STAT3/ATP6V1A/ACAT1/PARP9/PRKAA1/DIP2A/MAPK1/FAR1	31
GO:0071692	protein localization to extracellular region	24/988	368/18722	0.167340645733505	0.325204412950756	IGF1/VEGFC/NNAT/F2R/PCSK5/PAM/PRKCE/LTBP1/CANX/KIF5B/SLC12A2/CPT1A/TGFB1/GJA1/CD200/SEL1L/HIF1A/MAP4K4/ABCA1/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	24
GO:0051236	establishment of RNA localization	12/988	166/18722	0.1677928894992	0.325204412950756	HHEX/TGFBR2/ZFP36L1/RANBP2/QKI/ZFP36/ZC3H11A/MYO1C/FYTTD1/THOC2/SMG1/XPO1	12
GO:0042113	B cell activation	22/988	334/18722	0.168217435427804	0.325204412950756	FCGR2B/BST2/MEF2C/ITM2A/HHEX/AHR/ITGB1/MFNG/CD81/ZFP36L1/LGALS1/PKN1/TGFB1/LYL1/KLF6/RC3H1/IRF2BP2/ZFP36L2/CD320/KMT5B/RIF1/ID2	22
GO:0022406	membrane docking	7/988	86/18722	0.168219442765952	0.325204412950756	CAV2/MSN/CALM1/STX3/RALB/CTBP2/ROCK1	7
GO:0009101	glycoprotein biosynthetic process	21/988	317/18722	0.168457842223174	0.325204412950756	IGF1/IL33/EOGT/ITM2A/BMPR2/PLCB1/ITM2B/PHLDA1/ST6GAL1/ST3GAL5/FUT11/CHSY1/MGAT4A/OGT/EDEM3/MAN1A1/MAGT1/DPY19L4/B4GALT5/RPN1/TMTC3	21
GO:0001835	blastocyst hatching	3/988	27/18722	0.168488513398179	0.325204412950756	LPAR6/BCOR/CMTM3	3
GO:0002719	negative regulation of cytokine production involved in immune response	3/988	27/18722	0.168488513398179	0.325204412950756	BST2/ANGPT1/TGFB1	3
GO:0007026	negative regulation of microtubule depolymerization	3/988	27/18722	0.168488513398179	0.325204412950756	TAOK1/APC/CAMSAP2	3
GO:0010586	miRNA metabolic process	3/988	27/18722	0.168488513398179	0.325204412950756	DDX17/DICER1/RC3H1	3
GO:0032703	negative regulation of interleukin-2 production	3/988	27/18722	0.168488513398179	0.325204412950756	CD34/HDAC7/ZFP36	3
GO:0035188	hatching	3/988	27/18722	0.168488513398179	0.325204412950756	LPAR6/BCOR/CMTM3	3
GO:0035459	vesicle cargo loading	3/988	27/18722	0.168488513398179	0.325204412950756	PICALM/SEC23A/SEC31A	3
GO:0039529	RIG-I signaling pathway	3/988	27/18722	0.168488513398179	0.325204412950756	SEC14L1/DDX60/PUM2	3
GO:0045830	positive regulation of isotype switching	3/988	27/18722	0.168488513398179	0.325204412950756	TGFB1/KMT5B/RIF1	3
GO:0060142	regulation of syncytium formation by plasma membrane fusion	3/988	27/18722	0.168488513398179	0.325204412950756	EHD2/CFLAR/CAPN2	3
GO:0060512	prostate gland morphogenesis	3/988	27/18722	0.168488513398179	0.325204412950756	HOXA13/NOTCH1/FEM1B	3
GO:0071624	positive regulation of granulocyte chemotaxis	3/988	27/18722	0.168488513398179	0.325204412950756	EDN1/MDK/MOSPD2	3
GO:0071684	organism emergence from protective structure	3/988	27/18722	0.168488513398179	0.325204412950756	LPAR6/BCOR/CMTM3	3
GO:0098901	regulation of cardiac muscle cell action potential	3/988	27/18722	0.168488513398179	0.325204412950756	CAV1/CALM1/GJA5	3
GO:1900746	regulation of vascular endothelial growth factor signaling pathway	3/988	27/18722	0.168488513398179	0.325204412950756	ADGRA2/TSPAN12/MYO1C	3
GO:1902914	regulation of protein polyubiquitination	3/988	27/18722	0.168488513398179	0.325204412950756	SASH1/XIAP/TRIP12	3
GO:1903319	positive regulation of protein maturation	3/988	27/18722	0.168488513398179	0.325204412950756	CLEC3B/MYH9/GSN	3
GO:1903421	regulation of synaptic vesicle recycling	3/988	27/18722	0.168488513398179	0.325204412950756	SYT11/CALM1/ROCK1	3
GO:0010907	positive regulation of glucose metabolic process	4/988	41/18722	0.168846718922851	0.325204412950756	IGF1/NNMT/IGF2/ARPP19	4
GO:0032733	positive regulation of interleukin-10 production	4/988	41/18722	0.168846718922851	0.325204412950756	CD34/ISG15/STAT3/CD46	4
GO:0042307	positive regulation of protein import into nucleus	4/988	41/18722	0.168846718922851	0.325204412950756	HYAL2/TGFB1/FLNA/MAPK1	4
GO:0048286	lung alveolus development	4/988	41/18722	0.168846718922851	0.325204412950756	FOXF1/BMPR2/CREB1/LTBP3	4
GO:0050892	intestinal absorption	4/988	41/18722	0.168846718922851	0.325204412950756	SCARB1/UGCG/CD36/F11R	4
GO:0060612	adipose tissue development	4/988	41/18722	0.168846718922851	0.325204412950756	SPTLC2/PIK3CA/ACAT1/ATF2	4
GO:0070296	sarcoplasmic reticulum calcium ion transport	4/988	41/18722	0.168846718922851	0.325204412950756	PDE4D/CLIC2/CALM1/ZMPSTE24	4
GO:0071470	cellular response to osmotic stress	4/988	41/18722	0.168846718922851	0.325204412950756	LRRC8C/ZFP36L1/PKD2/SLC2A1	4
GO:1902106	negative regulation of leukocyte differentiation	8/988	102/18722	0.170415385344952	0.32810675134193	FCGR2B/HLX/CEACAM1/CDK6/MDK/GATA2/RC3H1/ID2	8
GO:0002705	positive regulation of leukocyte mediated immunity	10/988	134/18722	0.170602531781916	0.328348061168673	IL1R1/HLA-E/HLA-A/HLA-B/B2M/CD81/TGFB1/LAMP1/KMT5B/RIF1	10
GO:0050795	regulation of behavior	6/988	71/18722	0.171267250609361	0.329508017108629	LEPR/MEF2C/MDK/ADRB1/GJA1/STAT3	6
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	5/988	56/18722	0.172209696030194	0.330722308500503	HLA-E/HLA-A/HLA-B/B2M/LAMP1	5
GO:0010332	response to gamma radiation	5/988	56/18722	0.172209696030194	0.330722308500503	PML/EGR1/TRIM13/PRKAA1/ZMPSTE24	5
GO:0022029	telencephalon cell migration	5/988	56/18722	0.172209696030194	0.330722308500503	DIXDC1/RHOA/SUN1/ZMIZ1/RTN4	5
GO:0042733	embryonic digit morphogenesis	5/988	56/18722	0.172209696030194	0.330722308500503	ECE1/NOTCH1/TBX3/FZD6/SMAD4	5
GO:0070534	protein K63-linked ubiquitination	5/988	56/18722	0.172209696030194	0.330722308500503	SASH1/HECTD1/TRIP12/UBE2E3/NEDD4	5
GO:0072522	purine-containing compound biosynthetic process	14/988	200/18722	0.172415415134859	0.330997717815819	PAPSS2/NT5E/ADCY4/NPR1/TMSB4X/PDK4/TGFB1/ACSL3/ELOVL5/HSD17B12/STAT3/ATP6V1A/ACAT1/DIP2A	14
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	12/988	167/18722	0.172719391246581	0.331341786313412	PECAM1/CDH5/ESAM/ROBO4/HMCN1/CEACAM1/PCDH12/DCHS1/ITGB1/PALLD/PTPRM/NPTN	12
GO:0034767	positive regulation of ion transmembrane transport	12/988	167/18722	0.172719391246581	0.331341786313412	APLNR/RAMP3/F2R/ITGB1/TMSB4X/KIF5B/ACTN4/CALM1/STIM2/FLNA/PKD2/WNK1	12
GO:0009100	glycoprotein metabolic process	25/988	387/18722	0.173113138476509	0.331977253280583	IGF1/IL33/NDNF/EOGT/ITM2A/BMPR2/PLCB1/ITM2B/PHLDA1/ST6GAL1/ST3GAL5/FUT11/SULF2/CHSY1/MGAT4A/HIF1A/OGT/EDEM3/MAN1A1/MAGT1/DPY19L4/TRIM13/B4GALT5/RPN1/TMTC3	25
GO:1904064	positive regulation of cation transmembrane transport	11/988	151/18722	0.174677734209867	0.33485677521574	APLNR/RAMP3/F2R/TMSB4X/KIF5B/ACTN4/CALM1/STIM2/FLNA/PKD2/WNK1	11
GO:0007029	endoplasmic reticulum organization	7/988	87/18722	0.175227401333486	0.335789305874271	CAV2/TMCC1/ATL3/TRAM1/RTN4/SEC31A/SEC61A1	7
GO:0050708	regulation of protein secretion	18/988	268/18722	0.175844177142112	0.336849718347962	IGF1/VEGFC/NNAT/F2R/PAM/PRKCE/KIF5B/SLC12A2/CPT1A/TGFB1/GJA1/CD200/HIF1A/MAP4K4/CLOCK/PPP3CA/PIM3/MIDN	18
GO:0032760	positive regulation of tumor necrosis factor production	8/988	103/18722	0.176857149184276	0.338546009537612	IL33/HLA-E/THBS1/CLU/APP/OAS2/CD36/STAT3	8
GO:0046425	regulation of receptor signaling pathway via JAK-STAT	8/988	103/18722	0.176857149184276	0.338546009537612	F2R/CAV1/NOTCH1/SH2B3/SOCS3/PARP14/LEPROT/HES1	8
GO:2000241	regulation of reproductive process	12/988	168/18722	0.177715866277251	0.340067248438313	IGF1/P2RY1/RPS6KA2/PLCB1/NOTCH1/TIMP1/SMURF2/DUSP1/GJA1/CDC25B/PRKAR1A/MYH9	12
GO:0000271	polysaccharide biosynthetic process	6/988	72/18722	0.179123181137582	0.341783506344806	IGF1/IGF2/PDGFB/TGFB1/GBE1/B4GALT5	6
GO:0050709	negative regulation of protein secretion	6/988	72/18722	0.179123181137582	0.341783506344806	F2R/CD200/MAP4K4/PPP3CA/PIM3/MIDN	6
GO:0071479	cellular response to ionizing radiation	6/988	72/18722	0.179123181137582	0.341783506344806	IFI16/RHOB/EGR1/CLOCK/NIPBL/ZMPSTE24	6
GO:0009416	response to light stimulus	21/988	320/18722	0.179148591105926	0.341783506344806	HYAL2/TANC1/ITGB1/TIMP1/CARD16/APP/GNAQ/DUSP1/PML/TP53INP1/HIF1A/POLK/CREB1/NPTN/CLOCK/CCND1/PRKAA1/ID2/PIAS1/NEDD4/BHLHE40	21
GO:0000413	protein peptidyl-prolyl isomerization	4/988	42/18722	0.179384867411393	0.341783506344806	FKBP1A/FKBP9/RANBP2/NKTR	4
GO:0007212	dopamine receptor signaling pathway	4/988	42/18722	0.179384867411393	0.341783506344806	CAV2/GNB1/FLNA/ARPP19	4
GO:0010677	negative regulation of cellular carbohydrate metabolic process	4/988	42/18722	0.179384867411393	0.341783506344806	LEPR/GIT1/STAT3/MIDN	4
GO:0010939	regulation of necrotic cell death	4/988	42/18722	0.179384867411393	0.341783506344806	CAV1/CFLAR/OGT/CYLD	4
GO:0014003	oligodendrocyte development	4/988	42/18722	0.179384867411393	0.341783506344806	CLU/PTEN/CD9/B4GALT5	4
GO:0045214	sarcomere organization	4/988	42/18722	0.179384867411393	0.341783506344806	EDN1/ITGB1/PRKAR1A/PLEC	4
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	4/988	42/18722	0.179384867411393	0.341783506344806	CNOT6L/CNOT8/CNOT2/XRN1	4
GO:1904037	positive regulation of epithelial cell apoptotic process	4/988	42/18722	0.179384867411393	0.341783506344806	THBS1/RGCC/GSN/TIA1	4
GO:0030219	megakaryocyte differentiation	5/988	57/18722	0.181180217219772	0.344763431491858	FLI1/MEF2C/SH2B3/GABPA/GATA2	5
GO:0002675	positive regulation of acute inflammatory response	3/988	28/18722	0.181792615137179	0.344763431491858	HLA-E/OSMR/IL6ST	3
GO:0006972	hyperosmotic response	3/988	28/18722	0.181792615137179	0.344763431491858	SLC12A2/PKN1/SLC2A1	3
GO:0009065	glutamine family amino acid catabolic process	3/988	28/18722	0.181792615137179	0.344763431491858	GLS/DDAH2/ATP2B4	3
GO:0010460	positive regulation of heart rate	3/988	28/18722	0.181792615137179	0.344763431491858	EDN1/PDE4D/ADRB1	3
GO:0010464	regulation of mesenchymal cell proliferation	3/988	28/18722	0.181792615137179	0.344763431491858	NFIB/FOXF1/TGFBR2	3
GO:0019098	reproductive behavior	3/988	28/18722	0.181792615137179	0.344763431491858	THRA/APP/PTEN	3
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3/988	28/18722	0.181792615137179	0.344763431491858	ITGA1/SOCS4/CBLB	3
GO:0061082	myeloid leukocyte cytokine production	3/988	28/18722	0.181792615137179	0.344763431491858	TGFB1/CD36/BCL10	3
GO:0099623	regulation of cardiac muscle cell membrane repolarization	3/988	28/18722	0.181792615137179	0.344763431491858	FLNA/GJA5/ZMPSTE24	3
GO:1903020	positive regulation of glycoprotein metabolic process	3/988	28/18722	0.181792615137179	0.344763431491858	IGF1/IL33/PLCB1	3
GO:1903649	regulation of cytoplasmic transport	3/988	28/18722	0.181792615137179	0.344763431491858	MSN/RDX/MAPK1	3
GO:1903671	negative regulation of sprouting angiogenesis	3/988	28/18722	0.181792615137179	0.344763431491858	KLF2/THBS1/SYNJ2BP	3
GO:0007052	mitotic spindle organization	9/988	120/18722	0.183070994220867	0.346940107492416	FLNA/RHOA/TACC1/STAG2/MAP4/RAB11A/DYNC1H1/HSPA1A/PLK2	9
GO:0048593	camera-type eye morphogenesis	9/988	120/18722	0.183070994220867	0.346940107492416	JAG1/TSPAN12/HIPK2/ABI2/HIF1A/SKI/PTPRM/PHACTR4/HIPK1	9
GO:0022411	cellular component disassembly	28/988	443/18722	0.185709214914682	0.347494341209612	SPTBN1/FSCN1/ADAM15/ETS1/SPTAN1/KIF5B/LAMC1/DICER1/CALM1/TGFB1/TAOK1/PIK3CA/TMOD3/SETX/RDX/HIF1A/MAP4K4/ADAM10/RB1CC1/CTTN/VPS13C/ADD1/APC/GSN/ARID1A/DSTN/CAMSAP2/ZMPSTE24	28
GO:0002070	epithelial cell maturation	2/988	15/18722	0.185980122752057	0.347494341209612	HIF1A/FEM1B	2
GO:0002468	dendritic cell antigen processing and presentation	2/988	15/18722	0.185980122752057	0.347494341209612	FCGR2B/THBS1	2
GO:0006268	DNA unwinding involved in DNA replication	2/988	15/18722	0.185980122752057	0.347494341209612	PURA/RECQL	2
GO:0010452	histone H3-K36 methylation	2/988	15/18722	0.185980122752057	0.347494341209612	BCOR/ASH1L	2
GO:0010752	regulation of cGMP-mediated signaling	2/988	15/18722	0.185980122752057	0.347494341209612	NPR1/THBS1	2
GO:0010820	positive regulation of T cell chemotaxis	2/988	15/18722	0.185980122752057	0.347494341209612	ADAM10/WNK1	2
GO:0023035	CD40 signaling pathway	2/988	15/18722	0.185980122752057	0.347494341209612	ITGA5/ITGB1	2
GO:0033599	regulation of mammary gland epithelial cell proliferation	2/988	15/18722	0.185980122752057	0.347494341209612	RTN4/CCND1	2
GO:0034638	phosphatidylcholine catabolic process	2/988	15/18722	0.185980122752057	0.347494341209612	ENPP2/SCARB1	2
GO:0042994	cytoplasmic sequestering of transcription factor	2/988	15/18722	0.185980122752057	0.347494341209612	TMSB4X/PKD2	2
GO:0043508	negative regulation of JUN kinase activity	2/988	15/18722	0.185980122752057	0.347494341209612	AIDA/HIPK3	2
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	2/988	15/18722	0.185980122752057	0.347494341209612	CD44/DYRK1A	2
GO:0043981	histone H4-K5 acetylation	2/988	15/18722	0.185980122752057	0.347494341209612	OGT/KANSL1	2
GO:0043982	histone H4-K8 acetylation	2/988	15/18722	0.185980122752057	0.347494341209612	OGT/KANSL1	2
GO:0044406	adhesion of symbiont to host	2/988	15/18722	0.185980122752057	0.347494341209612	SCARB1/CD81	2
GO:0045176	apical protein localization	2/988	15/18722	0.185980122752057	0.347494341209612	JAM3/RDX	2
GO:0045725	positive regulation of glycogen biosynthetic process	2/988	15/18722	0.185980122752057	0.347494341209612	IGF1/IGF2	2
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	2/988	15/18722	0.185980122752057	0.347494341209612	RB1/CDC27	2
GO:0045986	negative regulation of smooth muscle contraction	2/988	15/18722	0.185980122752057	0.347494341209612	CALCRL/DOCK4	2
GO:0048484	enteric nervous system development	2/988	15/18722	0.185980122752057	0.347494341209612	HLX/PHACTR4	2
GO:0048569	post-embryonic animal organ development	2/988	15/18722	0.185980122752057	0.347494341209612	KLF4/EFEMP1	2
GO:0051608	histamine transport	2/988	15/18722	0.185980122752057	0.347494341209612	EDN1/SNAP23	2
GO:0055012	ventricular cardiac muscle cell differentiation	2/988	15/18722	0.185980122752057	0.347494341209612	MEF2C/MEF2A	2
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	2/988	15/18722	0.185980122752057	0.347494341209612	RCAN1/ATP2B4	2
GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	2/988	15/18722	0.185980122752057	0.347494341209612	IGF1/LMCD1	2
GO:0071871	response to epinephrine	2/988	15/18722	0.185980122752057	0.347494341209612	PDE4B/ATP2B4	2
GO:0072075	metanephric mesenchyme development	2/988	15/18722	0.185980122752057	0.347494341209612	PKD2/SMAD4	2
GO:0080154	regulation of fertilization	2/988	15/18722	0.185980122752057	0.347494341209612	PLCB1/MYH9	2
GO:0090110	COPII-coated vesicle cargo loading	2/988	15/18722	0.185980122752057	0.347494341209612	SEC23A/SEC31A	2
GO:0106057	negative regulation of calcineurin-mediated signaling	2/988	15/18722	0.185980122752057	0.347494341209612	RCAN1/ATP2B4	2
GO:0106058	positive regulation of calcineurin-mediated signaling	2/988	15/18722	0.185980122752057	0.347494341209612	IGF1/LMCD1	2
GO:0140374	antiviral innate immune response	2/988	15/18722	0.185980122752057	0.347494341209612	CARD8/MX1	2
GO:1901660	calcium ion export	2/988	15/18722	0.185980122752057	0.347494341209612	CALM1/ATP2B4	2
GO:1901741	positive regulation of myoblast fusion	2/988	15/18722	0.185980122752057	0.347494341209612	EHD2/CAPN2	2
GO:1901841	regulation of high voltage-gated calcium channel activity	2/988	15/18722	0.185980122752057	0.347494341209612	CALM1/PDE4B	2
GO:1901970	positive regulation of mitotic sister chromatid separation	2/988	15/18722	0.185980122752057	0.347494341209612	RB1/CDC27	2
GO:1903543	positive regulation of exosomal secretion	2/988	15/18722	0.185980122752057	0.347494341209612	SDCBP/PDCD6IP	2
GO:1904380	endoplasmic reticulum mannose trimming	2/988	15/18722	0.185980122752057	0.347494341209612	EDEM3/TRIM13	2
GO:2000650	negative regulation of sodium ion transmembrane transporter activity	2/988	15/18722	0.185980122752057	0.347494341209612	PRKCE/NEDD4	2
GO:0032456	endocytic recycling	6/988	73/18722	0.18712085854243	0.349011938404982	EHD2/ANKRD50/ACAP2/KIAA1109/EHD4/RAB11A	6
GO:0045739	positive regulation of DNA repair	6/988	73/18722	0.18712085854243	0.349011938404982	SLF2/ACTR2/PARP9/DTX3L/KMT5B/RIF1	6
GO:0051865	protein autoubiquitination	6/988	73/18722	0.18712085854243	0.349011938404982	SASH1/RNF11/HECTD1/TRIM13/DTX3L/RNF213	6
GO:0099518	vesicle cytoskeletal trafficking	6/988	73/18722	0.18712085854243	0.349011938404982	KIF5B/ACTN4/MYO1C/DYNC1H1/WASL/KIFAP3	6
GO:1904427	positive regulation of calcium ion transmembrane transport	6/988	73/18722	0.18712085854243	0.349011938404982	APLNR/RAMP3/F2R/CALM1/STIM2/PKD2	6
GO:0000086	G2/M transition of mitotic cell cycle	10/988	137/18722	0.187569884167287	0.349726649595167	PLCB1/APP/CCNY/CALM1/TAOK1/CDC25B/ARPP19/CCND1/RAB11A/FOXN3	10
GO:0019318	hexose metabolic process	16/988	237/18722	0.187662448519405	0.349776465450905	IGFBP4/IGF1/NNMT/LEPR/FABP5/IGF2/PDK4/CPT1A/PIK3CA/KBTBD2/RANBP2/OGT/ARPP19/PRKAA1/MIDN/ZMPSTE24	16
GO:0009165	nucleotide biosynthetic process	17/988	254/18722	0.187869918442811	0.350040339097936	NNMT/IDO1/PAPSS2/ADCY4/NPR1/TMSB4X/PDK4/TGFB1/ACSL3/ELOVL5/HSD17B12/STAT3/ATP6V1A/ACAT1/PARP9/DIP2A/MAPK1	17
GO:0016079	synaptic vesicle exocytosis	8/988	105/18722	0.190055527598	0.352900598790412	P2RY1/GIT1/CALM1/STX3/SNAP23/CTBP2/RAB5A/RAP1A	8
GO:0006458	'de novo' protein folding	4/988	43/18722	0.190135827134443	0.352900598790412	FKBP1A/ERO1A/HSPA1A/HSPH1	4
GO:0014002	astrocyte development	4/988	43/18722	0.190135827134443	0.352900598790412	VIM/LAMB2/APP/CDK6	4
GO:0014014	negative regulation of gliogenesis	4/988	43/18722	0.190135827134443	0.352900598790412	NOTCH1/DICER1/SKI/HES1	4
GO:0021983	pituitary gland development	4/988	43/18722	0.190135827134443	0.352900598790412	ETS1/CREB1/GATA2/HES1	4
GO:0032365	intracellular lipid transport	4/988	43/18722	0.190135827134443	0.352900598790412	LRP6/CPT1A/ABCA1/STARD4	4
GO:0046636	negative regulation of alpha-beta T cell activation	4/988	43/18722	0.190135827134443	0.352900598790412	HLX/TNFRSF14/RC3H1/CBLB	4
GO:0060443	mammary gland morphogenesis	4/988	43/18722	0.190135827134443	0.352900598790412	CAV1/TGFBR2/PML/TBX3	4
GO:0120178	steroid hormone biosynthetic process	4/988	43/18722	0.190135827134443	0.352900598790412	HSD17B2/SCARB1/HSD17B12/EGR1	4
GO:1904591	positive regulation of protein import	4/988	43/18722	0.190135827134443	0.352900598790412	HYAL2/TGFB1/FLNA/MAPK1	4
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	4/988	43/18722	0.190135827134443	0.352900598790412	FGFR1/FYN/CTNNA1/HSPA1A	4
GO:0010559	regulation of glycoprotein biosynthetic process	5/988	58/18722	0.190319667076405	0.352995136700372	IGF1/IL33/ITM2A/PLCB1/ITM2B	5
GO:1902808	positive regulation of cell cycle G1/S phase transition	5/988	58/18722	0.190319667076405	0.352995136700372	PLCB1/RGCC/KMT2E/RDX/CCND1	5
GO:0051168	nuclear export	11/988	154/18722	0.190813543145204	0.353787623451074	IFI27/HHEX/TGFB1/ZC3H11A/FYTTD1/THOC2/SP100/PTPN14/SMG1/XPO1/CTDSPL2	11
GO:0001906	cell killing	13/988	188/18722	0.194688116248875	0.360365467028048	FCGR2B/CEACAM1/HLA-E/HLA-A/HLA-B/B2M/KIF5B/LYST/LAMP1/CD59/RAB27A/EMP2/CRK	13
GO:1901568	fatty acid derivative metabolic process	6/988	74/18722	0.195254501230996	0.360365467028048	PAM/ACSL3/ELOVL5/HSD17B12/ACAT1/FAR1	6
GO:0009310	amine catabolic process	3/988	29/18722	0.195365183578486	0.360365467028048	IDO1/SLC44A1/ATP2B4	3
GO:0019359	nicotinamide nucleotide biosynthetic process	3/988	29/18722	0.195365183578486	0.360365467028048	NNMT/IDO1/PARP9	3
GO:0019363	pyridine nucleotide biosynthetic process	3/988	29/18722	0.195365183578486	0.360365467028048	NNMT/IDO1/PARP9	3
GO:0032366	intracellular sterol transport	3/988	29/18722	0.195365183578486	0.360365467028048	LRP6/ABCA1/STARD4	3
GO:0032367	intracellular cholesterol transport	3/988	29/18722	0.195365183578486	0.360365467028048	LRP6/ABCA1/STARD4	3
GO:0033028	myeloid cell apoptotic process	3/988	29/18722	0.195365183578486	0.360365467028048	MEF2C/THRA/PTEN	3
GO:0034311	diol metabolic process	3/988	29/18722	0.195365183578486	0.360365467028048	PLPP1/SPTLC2/PLPP3	3
GO:0043153	entrainment of circadian clock by photoperiod	3/988	29/18722	0.195365183578486	0.360365467028048	PML/ID2/BHLHE40	3
GO:0050686	negative regulation of mRNA processing	3/988	29/18722	0.195365183578486	0.360365467028048	DYRK1A/HNRNPK/CCNT1	3
GO:0071549	cellular response to dexamethasone stimulus	3/988	29/18722	0.195365183578486	0.360365467028048	FOXO1/CFLAR/NR3C1	3
GO:0098868	bone growth	3/988	29/18722	0.195365183578486	0.360365467028048	LEPR/TGFBR2/ZMPSTE24	3
GO:1901017	negative regulation of potassium ion transmembrane transporter activity	3/988	29/18722	0.195365183578486	0.360365467028048	CAV1/PTEN/CRBN	3
GO:0031109	microtubule polymerization or depolymerization	9/988	122/18722	0.195472308708432	0.360365467028048	CDH5/GIT1/TAOK1/APC/ARHGEF7/DYRK1A/HSPA1A/CAMSAP2/NIN	9
GO:0050868	negative regulation of T cell activation	9/988	122/18722	0.195472308708432	0.360365467028048	FCGR2B/LRRC32/HLX/CEACAM1/MDK/PRKAR1A/TNFRSF14/RC3H1/CBLB	9
GO:0009306	protein secretion	23/988	359/18722	0.195514547435021	0.360365467028048	IGF1/VEGFC/NNAT/F2R/PCSK5/PAM/PRKCE/CANX/KIF5B/SLC12A2/CPT1A/TGFB1/GJA1/CD200/SEL1L/HIF1A/MAP4K4/ABCA1/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	23
GO:1901293	nucleoside phosphate biosynthetic process	17/988	256/18722	0.196350476647414	0.361780690929957	NNMT/IDO1/PAPSS2/ADCY4/NPR1/TMSB4X/PDK4/TGFB1/ACSL3/ELOVL5/HSD17B12/STAT3/ATP6V1A/ACAT1/PARP9/DIP2A/MAPK1	17
GO:0072593	reactive oxygen species metabolic process	16/988	239/18722	0.196448513485133	0.361835819567624	EDN1/PRCP/THBS1/TGFBR2/PDGFB/PDK4/GNAI2/TGFB1/CFLAR/FYN/CD36/RAB27A/RHOA/HIF1A/STAT3/CLCN3	16
GO:1903707	negative regulation of hemopoiesis	8/988	106/18722	0.196806161497972	0.362368918501638	FCGR2B/HLX/CEACAM1/CDK6/MDK/GATA2/RC3H1/ID2	8
GO:0032392	DNA geometric change	7/988	90/18722	0.196972441936802	0.362423834973429	CHD9/ATRX/SETX/PURA/RECQL/G3BP1/CHD3	7
GO:0046849	bone remodeling	7/988	90/18722	0.196972441936802	0.362423834973429	LEPR/S1PR1/PDK4/MDK/TGFB1/GJA1/LTBP3	7
GO:0035592	establishment of protein localization to extracellular region	23/988	360/18722	0.199127341307569	0.36626192417791	IGF1/VEGFC/NNAT/F2R/PCSK5/PAM/PRKCE/CANX/KIF5B/SLC12A2/CPT1A/TGFB1/GJA1/CD200/SEL1L/HIF1A/MAP4K4/ABCA1/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	23
GO:0006406	mRNA export from nucleus	5/988	59/18722	0.199619098293839	0.366405200461946	HHEX/ZC3H11A/FYTTD1/THOC2/SMG1	5
GO:0021885	forebrain cell migration	5/988	59/18722	0.199619098293839	0.366405200461946	DIXDC1/RHOA/SUN1/ZMIZ1/RTN4	5
GO:0046324	regulation of glucose import	5/988	59/18722	0.199619098293839	0.366405200461946	IGF1/MEF2A/PEA15/ARPP19/RAP1A	5
GO:0051353	positive regulation of oxidoreductase activity	5/988	59/18722	0.199619098293839	0.366405200461946	EDN1/SCARB1/GNAI2/CALM1/HIF1A	5
GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	5/988	59/18722	0.199619098293839	0.366405200461946	HHEX/ZC3H11A/FYTTD1/THOC2/SMG1	5
GO:2001258	negative regulation of cation channel activity	5/988	59/18722	0.199619098293839	0.366405200461946	CAV1/CLIC2/CALM1/PKD2/CRBN	5
GO:0030217	T cell differentiation	17/988	257/18722	0.200658720889227	0.368186226377746	LEPR/HLX/FOXP1/TGFBR2/B2M/ZFP36L1/MDK/RHOA/STAT3/ZMIZ1/EGR1/RC3H1/ZFP36L2/CD46/ATF2/SOS2/SOS1	17
GO:0002066	columnar/cuboidal epithelial cell development	4/988	44/18722	0.201084277250713	0.368585121033743	CDK6/IL6ST/HIF1A/CLOCK	4
GO:0032881	regulation of polysaccharide metabolic process	4/988	44/18722	0.201084277250713	0.368585121033743	IGF1/IGF2/PDGFB/TGFB1	4
GO:1903214	regulation of protein targeting to mitochondrion	4/988	44/18722	0.201084277250713	0.368585121033743	ABLIM3/LEPROT/PRKAA1/SH3GLB1	4
GO:0031570	DNA integrity checkpoint signaling	9/988	123/18722	0.201803888305252	0.369776562496549	PML/TAOK1/FEM1B/CLOCK/CCND1/WAC/ATF2/FOXN3/PLK2	9
GO:1903363	negative regulation of cellular protein catabolic process	6/988	75/18722	0.203518184905725	0.371244978472585	HIPK2/PML/OGT/RYBP/SDCBP/WAC	6
GO:0008637	apoptotic mitochondrial changes	8/988	107/18722	0.203653612709023	0.371244978472585	IGF1/TNFSF10/CLU/IFIT2/PPP2CB/ATF2/HSPA1A/JUN	8
GO:0051341	regulation of oxidoreductase activity	8/988	107/18722	0.203653612709023	0.371244978472585	EDN1/CAV1/SCARB1/GNAI2/DDAH2/CALM1/HIF1A/ATP2B4	8
GO:0002065	columnar/cuboidal epithelial cell differentiation	7/988	91/18722	0.204447539169359	0.371244978472585	NOTCH1/CDK6/IL6ST/HIF1A/CLOCK/HES1/SAV1	7
GO:0046390	ribose phosphate biosynthetic process	13/988	190/18722	0.204812473631634	0.371244978472585	PAPSS2/ADCY4/NPR1/TMSB4X/PDK4/TGFB1/ACSL3/ELOVL5/HSD17B12/STAT3/ATP6V1A/ACAT1/DIP2A	13
GO:0042593	glucose homeostasis	17/988	258/18722	0.205011395550143	0.371244978472585	ADGRF5/LEPR/ZBTB20/FOXO1/PRCP/PRKCE/FABP5/KIF5B/PDK4/LGALS1/PIK3CA/HIF1A/MAP4K4/STAT3/PPP3CA/PIM3/PRKAA1	17
GO:0001574	ganglioside biosynthetic process	2/988	16/18722	0.205540565076783	0.371244978472585	ST3GAL5/B4GALT5	2
GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	2/988	16/18722	0.205540565076783	0.371244978472585	F2R/PCSK5	2
GO:0002713	negative regulation of B cell mediated immunity	2/988	16/18722	0.205540565076783	0.371244978472585	FCGR2B/CD46	2
GO:0002890	negative regulation of immunoglobulin mediated immune response	2/988	16/18722	0.205540565076783	0.371244978472585	FCGR2B/CD46	2
GO:0006349	regulation of gene expression by genetic imprinting	2/988	16/18722	0.205540565076783	0.371244978472585	IGF2/PCGF5	2
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	2/988	16/18722	0.205540565076783	0.371244978472585	HIPK2/SP100	2
GO:0009048	dosage compensation by inactivation of X chromosome	2/988	16/18722	0.205540565076783	0.371244978472585	XIST/PCGF5	2
GO:0010819	regulation of T cell chemotaxis	2/988	16/18722	0.205540565076783	0.371244978472585	ADAM10/WNK1	2
GO:0017014	protein nitrosylation	2/988	16/18722	0.205540565076783	0.371244978472585	NCOA7/ATP2B4	2
GO:0018119	peptidyl-cysteine S-nitrosylation	2/988	16/18722	0.205540565076783	0.371244978472585	NCOA7/ATP2B4	2
GO:0019081	viral translation	2/988	16/18722	0.205540565076783	0.371244978472585	CSDE1/PCBP2	2
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	2/988	16/18722	0.205540565076783	0.371244978472585	ITGA5/HIF1A	2
GO:0034138	toll-like receptor 3 signaling pathway	2/988	16/18722	0.205540565076783	0.371244978472585	CAV1/WDFY1	2
GO:0035864	response to potassium ion	2/988	16/18722	0.205540565076783	0.371244978472585	CRHBP/SLC12A2	2
GO:0036342	post-anal tail morphogenesis	2/988	16/18722	0.205540565076783	0.371244978472585	TCF15/DCHS1	2
GO:0042481	regulation of odontogenesis	2/988	16/18722	0.205540565076783	0.371244978472585	CD34/EDN1	2
GO:0043923	positive regulation by host of viral transcription	2/988	16/18722	0.205540565076783	0.371244978472585	JUN/CCNT1	2
GO:0045722	positive regulation of gluconeogenesis	2/988	16/18722	0.205540565076783	0.371244978472585	NNMT/ARPP19	2
GO:0048385	regulation of retinoic acid receptor signaling pathway	2/988	16/18722	0.205540565076783	0.371244978472585	KLF2/CTBP2	2
GO:0050862	positive regulation of T cell receptor signaling pathway	2/988	16/18722	0.205540565076783	0.371244978472585	CD81/BCL10	2
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	2/988	16/18722	0.205540565076783	0.371244978472585	KDR/IL33	2
GO:0060330	regulation of response to interferon-gamma	2/988	16/18722	0.205540565076783	0.371244978472585	PARP14/PARP9	2
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	2/988	16/18722	0.205540565076783	0.371244978472585	PARP14/PARP9	2
GO:0061548	ganglion development	2/988	16/18722	0.205540565076783	0.371244978472585	NRP1/SEMA3F	2
GO:0070571	negative regulation of neuron projection regeneration	2/988	16/18722	0.205540565076783	0.371244978472585	PTEN/MAP4K4	2
GO:0098884	postsynaptic neurotransmitter receptor internalization	2/988	16/18722	0.205540565076783	0.371244978472585	AP2B1/PPP3R1	2
GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	2/988	16/18722	0.205540565076783	0.371244978472585	STX3/RAB11A	2
GO:0099010	modification of postsynaptic structure	2/988	16/18722	0.205540565076783	0.371244978472585	RHOA/CDC42	2
GO:0099633	protein localization to postsynaptic specialization membrane	2/988	16/18722	0.205540565076783	0.371244978472585	ADAM10/RAP1A	2
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	2/988	16/18722	0.205540565076783	0.371244978472585	ADAM10/RAP1A	2
GO:0140239	postsynaptic endocytosis	2/988	16/18722	0.205540565076783	0.371244978472585	AP2B1/PPP3R1	2
GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	2/988	16/18722	0.205540565076783	0.371244978472585	RB1/CDC27	2
GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2/988	16/18722	0.205540565076783	0.371244978472585	CD44/HNRNPK	2
GO:1902306	negative regulation of sodium ion transmembrane transport	2/988	16/18722	0.205540565076783	0.371244978472585	PRKCE/NEDD4	2
GO:1904683	regulation of metalloendopeptidase activity	2/988	16/18722	0.205540565076783	0.371244978472585	STAT3/PICALM	2
GO:1905906	regulation of amyloid fibril formation	2/988	16/18722	0.205540565076783	0.371244978472585	CLU/APP	2
GO:0051250	negative regulation of lymphocyte activation	11/988	157/18722	0.207595466490774	0.374498621550813	FCGR2B/LRRC32/HLX/CEACAM1/MDK/PKN1/PRKAR1A/TNFRSF14/RC3H1/CBLB/ID2	11
GO:0051851	modulation by host of symbiont process	5/988	60/18722	0.209069418267271	0.374498621550813	IFI27/CAV2/STOM/JUN/CCNT1	5
GO:0045619	regulation of lymphocyte differentiation	12/988	174/18722	0.209096628027092	0.374498621550813	HLX/TGFBR2/ZFP36L1/MDK/RHOA/ZMIZ1/RC3H1/ZFP36L2/CD46/SOS2/SOS1/ID2	12
GO:0003299	muscle hypertrophy in response to stress	3/988	30/18722	0.209174964258521	0.374498621550813	FOXO1/ATP2B4/PPP3CA	3
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3/988	30/18722	0.209174964258521	0.374498621550813	PDE4D/CLIC2/CALM1	3
GO:0014887	cardiac muscle adaptation	3/988	30/18722	0.209174964258521	0.374498621550813	FOXO1/ATP2B4/PPP3CA	3
GO:0014898	cardiac muscle hypertrophy in response to stress	3/988	30/18722	0.209174964258521	0.374498621550813	FOXO1/ATP2B4/PPP3CA	3
GO:0017145	stem cell division	3/988	30/18722	0.209174964258521	0.374498621550813	WWTR1/NOTCH1/ZFP36L2	3
GO:0034390	smooth muscle cell apoptotic process	3/988	30/18722	0.209174964258521	0.374498621550813	EDN1/IGF1/LRP6	3
GO:0034391	regulation of smooth muscle cell apoptotic process	3/988	30/18722	0.209174964258521	0.374498621550813	EDN1/IGF1/LRP6	3
GO:0034508	centromere complex assembly	3/988	30/18722	0.209174964258521	0.374498621550813	RB1/POGZ/SENP6	3
GO:0036258	multivesicular body assembly	3/988	30/18722	0.209174964258521	0.374498621550813	PDCD6IP/RAB11A/VPS36	3
GO:0036296	response to increased oxygen levels	3/988	30/18722	0.209174964258521	0.374498621550813	CAV1/FOXO1/ATP6V1A	3
GO:0044030	regulation of DNA methylation	3/988	30/18722	0.209174964258521	0.374498621550813	PIK3CA/KMT2A/ZMPSTE24	3
GO:0044788	modulation by host of viral process	3/988	30/18722	0.209174964258521	0.374498621550813	IFI27/CAV2/STOM	3
GO:0045577	regulation of B cell differentiation	3/988	30/18722	0.209174964258521	0.374498621550813	ZFP36L1/ZFP36L2/ID2	3
GO:0048147	negative regulation of fibroblast proliferation	3/988	30/18722	0.209174964258521	0.374498621550813	DACH1/TP53INP1/SKI	3
GO:0048799	animal organ maturation	3/988	30/18722	0.209174964258521	0.374498621550813	IGF1/DCHS1/RHOA	3
GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	3/988	30/18722	0.209174964258521	0.374498621550813	FCGR2B/CEACAM1/CBLB	3
GO:0060218	hematopoietic stem cell differentiation	3/988	30/18722	0.209174964258521	0.374498621550813	TCF15/N4BP2L2/EIF2AK2	3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	3/988	30/18722	0.209174964258521	0.374498621550813	TGFBR2/SERPINH1/ZMPSTE24	3
GO:0061311	cell surface receptor signaling pathway involved in heart development	3/988	30/18722	0.209174964258521	0.374498621550813	JAG1/NOTCH1/TGFB1	3
GO:0070229	negative regulation of lymphocyte apoptotic process	3/988	30/18722	0.209174964258521	0.374498621550813	FOXP1/HIF1A/BCL10	3
GO:0070498	interleukin-1-mediated signaling pathway	3/988	30/18722	0.209174964258521	0.374498621550813	IL1R1/PLCB1/EGR1	3
GO:0090314	positive regulation of protein targeting to membrane	3/988	30/18722	0.209174964258521	0.374498621550813	STOM/FYN/MYO1C	3
GO:1903579	negative regulation of ATP metabolic process	3/988	30/18722	0.209174964258521	0.374498621550813	GIT1/RHOA/STAT3	3
GO:0033500	carbohydrate homeostasis	17/988	259/18722	0.20940781430462	0.37478918786595	ADGRF5/LEPR/ZBTB20/FOXO1/PRCP/PRKCE/FABP5/KIF5B/PDK4/LGALS1/PIK3CA/HIF1A/MAP4K4/STAT3/PPP3CA/PIM3/PRKAA1	17
GO:0006164	purine nucleotide biosynthetic process	13/988	191/18722	0.209961211349695	0.375653066584567	PAPSS2/ADCY4/NPR1/TMSB4X/PDK4/TGFB1/ACSL3/ELOVL5/HSD17B12/STAT3/ATP6V1A/ACAT1/DIP2A	13
GO:0008584	male gonad development	10/988	141/18722	0.211307312566499	0.377776551327248	TNFSF10/ADAM15/ATRX/FLNA/RNF38/FNDC3A/CSDE1/CTNNA1/CCND1/SMAD4	10
GO:0021536	diencephalon development	6/988	76/18722	0.211905859605261	0.377776551327248	NDNF/ETS1/NRP1/CREB1/GATA2/HES1	6
GO:0071426	ribonucleoprotein complex export from nucleus	6/988	76/18722	0.211905859605261	0.377776551327248	HHEX/ZC3H11A/FYTTD1/THOC2/SMG1/XPO1	6
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	6/988	76/18722	0.211905859605261	0.377776551327248	IFI16/HIPK2/PML/HIPK1/CD44/HNRNPK	6
GO:0001708	cell fate specification	7/988	92/18722	0.212028912036258	0.377776551327248	SOX18/HOXA13/NOTCH1/ITGB1/NRP1/TBX3/APC	7
GO:0031058	positive regulation of histone modification	7/988	92/18722	0.212028912036258	0.377776551327248	APLNR/KMT2E/KMT2A/OGT/NIPBL/RIF1/SMAD4	7
GO:0070509	calcium ion import	7/988	92/18722	0.212028912036258	0.377776551327248	RAMP3/PDGFB/FYN/SLC30A1/PKD2/ATP2B4/ZMPSTE24	7
GO:1903351	cellular response to dopamine	7/988	92/18722	0.212028912036258	0.377776551327248	CAV2/ID1/GNB1/GABPA/FLNA/ARPP19/MAPK1	7
GO:0002920	regulation of humoral immune response	4/988	45/18722	0.212214839826903	0.377776551327248	A2M/FCGR2B/CD59/CD46	4
GO:0010824	regulation of centrosome duplication	4/988	45/18722	0.212214839826903	0.377776551327248	PDCD6IP/ROCK2/XPO1/PLK2	4
GO:0030850	prostate gland development	4/988	45/18722	0.212214839826903	0.377776551327248	HOXA13/NOTCH1/PTEN/FEM1B	4
GO:0051180	vitamin transport	4/988	45/18722	0.212214839826903	0.377776551327248	SCARB1/SLC2A1/CD320/SLC2A3	4
GO:0071354	cellular response to interleukin-6	4/988	45/18722	0.212214839826903	0.377776551327248	JAK1/IL6ST/STAT3/SMAD4	4
GO:1901985	positive regulation of protein acetylation	4/988	45/18722	0.212214839826903	0.377776551327248	TAOK1/PRKAA1/DIP2A/SMAD4	4
GO:2000273	positive regulation of signaling receptor activity	4/988	45/18722	0.212214839826903	0.377776551327248	EDN1/ITGB1/NRP1/HIF1A	4
GO:0090150	establishment of protein localization to membrane	17/988	260/18722	0.213847270154368	0.380555008060303	SPTBN1/MACF1/STOM/VAMP5/CALM1/TRAM1/STX3/FYN/ACSL3/SEC62/GDI1/SDCBP/MYO1C/CHM/RAB11A/SEC61A1/GOLGA7	17
GO:0051053	negative regulation of DNA metabolic process	9/988	125/18722	0.214716486605416	0.381845991579502	ACVRL1/DACH1/BMPR2/DUSP1/GJA1/KMT2A/TRIP12/RIF1/XRN1	9
GO:0071621	granulocyte chemotaxis	9/988	125/18722	0.214716486605416	0.381845991579502	EDN1/ITGA1/THBS1/MDK/JAM3/PDE4B/MOSPD2/PTK2/MAPK1	9
GO:0046546	development of primary male sexual characteristics	10/988	142/18722	0.217427598688653	0.386537953224271	TNFSF10/ADAM15/ATRX/FLNA/RNF38/FNDC3A/CSDE1/CTNNA1/CCND1/SMAD4	10
GO:0043266	regulation of potassium ion transport	8/988	109/18722	0.217626011332873	0.386761248645106	CAV1/ITGB1/KIF5B/PTEN/FLNA/CRBN/WNK1/NEDD4	8
GO:0050994	regulation of lipid catabolic process	5/988	61/18722	0.218661419974922	0.388341512172111	SCARB1/THRA/PRKCE/CPT1A/PRKAA1	5
GO:0060998	regulation of dendritic spine development	5/988	61/18722	0.218661419974922	0.388341512172111	MEF2C/PTEN/ACTR2/EIF4G2/PLK2	5
GO:0019217	regulation of fatty acid metabolic process	7/988	93/18722	0.219712153479147	0.389686463866854	CEACAM1/CAV1/FABP5/PDK4/CPT1A/LPGAT1/ELOVL5	7
GO:0032755	positive regulation of interleukin-6 production	7/988	93/18722	0.219712153479147	0.389686463866854	IL33/F2R/HYAL2/APP/CD36/STAT3/BCL10	7
GO:1901796	regulation of signal transduction by p53 class mediator	7/988	93/18722	0.219712153479147	0.389686463866854	NUAK1/HIPK2/CD44/KAT6A/DYRK1A/HNRNPK/ZMPSTE24	7
GO:1903350	response to dopamine	7/988	93/18722	0.219712153479147	0.389686463866854	CAV2/ID1/GNB1/GABPA/FLNA/ARPP19/MAPK1	7
GO:0031016	pancreas development	6/988	77/18722	0.220411366452509	0.390535416476226	FOXF1/IGF2/CDK6/CLOCK/SMAD2/HES1	6
GO:0055117	regulation of cardiac muscle contraction	6/988	77/18722	0.220411366452509	0.390535416476226	CAV1/PDE4D/CLIC2/CALM1/PDE4B/GJA5	6
GO:0071166	ribonucleoprotein complex localization	6/988	77/18722	0.220411366452509	0.390535416476226	HHEX/ZC3H11A/FYTTD1/THOC2/SMG1/XPO1	6
GO:0006613	cotranslational protein targeting to membrane	3/988	31/18722	0.223191452586303	0.393432464625174	TRAM1/SEC62/SEC61A1	3
GO:0031063	regulation of histone deacetylation	3/988	31/18722	0.223191452586303	0.393432464625174	APLNR/SKI/NIPBL	3
GO:0031114	regulation of microtubule depolymerization	3/988	31/18722	0.223191452586303	0.393432464625174	TAOK1/APC/CAMSAP2	3
GO:0032148	activation of protein kinase B activity	3/988	31/18722	0.223191452586303	0.393432464625174	IGF1/PDGFB/CCDC88A	3
GO:0035115	embryonic forelimb morphogenesis	3/988	31/18722	0.223191452586303	0.393432464625174	HOXA13/TBX3/NIPBL	3
GO:0043171	peptide catabolic process	3/988	31/18722	0.223191452586303	0.393432464625174	ECE1/ERAP1/LNPEP	3
GO:0060045	positive regulation of cardiac muscle cell proliferation	3/988	31/18722	0.223191452586303	0.393432464625174	MEF2C/NOTCH1/MAPK1	3
GO:0060795	cell fate commitment involved in formation of primary germ layer	3/988	31/18722	0.223191452586303	0.393432464625174	SMAD1/KLF4/ETS2	3
GO:0070633	transepithelial transport	3/988	31/18722	0.223191452586303	0.393432464625174	EDN1/ITPR1/SLC12A2	3
GO:0010828	positive regulation of glucose transmembrane transport	4/988	46/18722	0.223512140765826	0.393432464625174	IGF1/MEF2A/ARPP19/RAP1A	4
GO:0034198	cellular response to amino acid starvation	4/988	46/18722	0.223512140765826	0.393432464625174	SLC38A2/EIF2AK2/SH3GLB1/MAPK1	4
GO:0035094	response to nicotine	4/988	46/18722	0.223512140765826	0.393432464625174	EDN1/B2M/CREB1/MAPK1	4
GO:0043616	keratinocyte proliferation	4/988	46/18722	0.223512140765826	0.393432464625174	CD109/ZFP36L1/MDK/ZFP36	4
GO:0046839	phospholipid dephosphorylation	4/988	46/18722	0.223512140765826	0.393432464625174	PLPP1/PLPP3/PTEN/MTMR6	4
GO:0070828	heterochromatin organization	4/988	46/18722	0.223512140765826	0.393432464625174	MECOM/LOXL2/ATF7IP/BAZ2A	4
GO:0009408	response to heat	8/988	110/18722	0.224744287161023	0.393432464625174	CD34/IGF1/THBS1/IGFBP7/TP53INP1/ATXN3/HSPA1A/PSIP1	8
GO:0001710	mesodermal cell fate commitment	2/988	17/18722	0.225305263062835	0.393432464625174	SMAD1/KLF4	2
GO:0006677	glycosylceramide metabolic process	2/988	17/18722	0.225305263062835	0.393432464625174	UGCG/PRKAA1	2
GO:0006895	Golgi to endosome transport	2/988	17/18722	0.225305263062835	0.393432464625174	VPS13C/MON2	2
GO:0010831	positive regulation of myotube differentiation	2/988	17/18722	0.225305263062835	0.393432464625174	PIEZO1/ATP11A	2
GO:0010934	macrophage cytokine production	2/988	17/18722	0.225305263062835	0.393432464625174	TGFB1/CD36	2
GO:0010935	regulation of macrophage cytokine production	2/988	17/18722	0.225305263062835	0.393432464625174	TGFB1/CD36	2
GO:0016045	detection of bacterium	2/988	17/18722	0.225305263062835	0.393432464625174	HLA-A/HLA-B	2
GO:0020027	hemoglobin metabolic process	2/988	17/18722	0.225305263062835	0.393432464625174	KLF4/HIF1A	2
GO:0030002	cellular anion homeostasis	2/988	17/18722	0.225305263062835	0.393432464625174	SLC12A2/XPR1	2
GO:0034349	glial cell apoptotic process	2/988	17/18722	0.225305263062835	0.393432464625174	RB1/PRKCH	2
GO:0035729	cellular response to hepatocyte growth factor stimulus	2/988	17/18722	0.225305263062835	0.393432464625174	NRP1/CREB1	2
GO:0035855	megakaryocyte development	2/988	17/18722	0.225305263062835	0.393432464625174	FLI1/SH2B3	2
GO:0042772	DNA damage response, signal transduction resulting in transcription	2/988	17/18722	0.225305263062835	0.393432464625174	HIPK2/SP100	2
GO:0042953	lipoprotein transport	2/988	17/18722	0.225305263062835	0.393432464625174	CD36/ZDHHC17	2
GO:0045815	positive regulation of gene expression, epigenetic	2/988	17/18722	0.225305263062835	0.393432464625174	ZMIZ1/ARID1A	2
GO:0048339	paraxial mesoderm development	2/988	17/18722	0.225305263062835	0.393432464625174	TCF15/SMAD2	2
GO:0048532	anatomical structure arrangement	2/988	17/18722	0.225305263062835	0.393432464625174	NRP1/SEMA3F	2
GO:0055003	cardiac myofibril assembly	2/988	17/18722	0.225305263062835	0.393432464625174	MEF2A/SMAD4	2
GO:0060977	coronary vasculature morphogenesis	2/988	17/18722	0.225305263062835	0.393432464625174	NOTCH1/NRP1	2
GO:0070875	positive regulation of glycogen metabolic process	2/988	17/18722	0.225305263062835	0.393432464625174	IGF1/IGF2	2
GO:0090083	regulation of inclusion body assembly	2/988	17/18722	0.225305263062835	0.393432464625174	CLU/HSPA1A	2
GO:0090136	epithelial cell-cell adhesion	2/988	17/18722	0.225305263062835	0.393432464625174	VCL/CTNNA1	2
GO:0097067	cellular response to thyroid hormone stimulus	2/988	17/18722	0.225305263062835	0.393432464625174	LMO2/RDX	2
GO:1903358	regulation of Golgi organization	2/988	17/18722	0.225305263062835	0.393432464625174	MAPK1/CAMSAP2	2
GO:1903540	establishment of protein localization to postsynaptic membrane	2/988	17/18722	0.225305263062835	0.393432464625174	STX3/RAB11A	2
GO:1903541	regulation of exosomal secretion	2/988	17/18722	0.225305263062835	0.393432464625174	SDCBP/PDCD6IP	2
GO:1903830	magnesium ion transmembrane transport	2/988	17/18722	0.225305263062835	0.393432464625174	MAGT1/ZDHHC17	2
GO:1904355	positive regulation of telomere capping	2/988	17/18722	0.225305263062835	0.393432464625174	NEK7/MAPK1	2
GO:0007588	excretion	5/988	62/18722	0.228385811662868	0.398288060260392	EDN1/NPR1/MDK/GNAI2/NFAT5	5
GO:0019933	cAMP-mediated signaling	5/988	62/18722	0.228385811662868	0.398288060260392	APLNR/ADGRG6/PDE4D/AHR/RAPGEF2	5
GO:0032757	positive regulation of interleukin-8 production	5/988	62/18722	0.228385811662868	0.398288060260392	F2R/HYAL2/STAT3/HSPA1A/BCL10	5
GO:0070265	necrotic cell death	5/988	62/18722	0.228385811662868	0.398288060260392	CAV1/TMEM123/CFLAR/OGT/CYLD	5
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	6/988	78/18722	0.229028454063952	0.399146702095707	F2R/HIP1/DLC1/PML/CFLAR/CARD8	6
GO:0070373	negative regulation of ERK1 and ERK2 cascade	6/988	78/18722	0.229028454063952	0.399146702095707	DUSP1/DUSP6/KLF4/PTEN/SYNJ2BP/SMAD4	6
GO:0043414	macromolecule methylation	20/988	316/18722	0.231247467011782	0.402881779195339	NNMT/MECOM/BCOR/KMT2E/ATRX/PIK3CA/KMT2A/OGT/FBXO11/PCMTD1/ASH1L/WDR82/ATF7IP/KMT5B/RIF1/PCMTD2/BTG2/SMAD4/BAZ2A/ZMPSTE24	20
GO:0010799	regulation of peptidyl-threonine phosphorylation	4/988	47/18722	0.234960866176035	0.408413652201276	APP/CALM1/TGFB1/MAPK1	4
GO:0031641	regulation of myelination	4/988	47/18722	0.234960866176035	0.408413652201276	JAM2/DICER1/PTEN/TNFRSF1B	4
GO:0045332	phospholipid translocation	4/988	47/18722	0.234960866176035	0.408413652201276	PLSCR4/ATP11A/ABCA1/PLSCR1	4
GO:0045911	positive regulation of DNA recombination	4/988	47/18722	0.234960866176035	0.408413652201276	TGFB1/ACTR2/KMT5B/RIF1	4
GO:0051972	regulation of telomerase activity	4/988	47/18722	0.234960866176035	0.408413652201276	HMBOX1/KLF4/NEK7/MAPK1	4
GO:0097300	programmed necrotic cell death	4/988	47/18722	0.234960866176035	0.408413652201276	CAV1/CFLAR/OGT/CYLD	4
GO:1903170	negative regulation of calcium ion transmembrane transport	4/988	47/18722	0.234960866176035	0.408413652201276	CLIC2/CALM1/SESTD1/PKD2	4
GO:1901379	regulation of potassium ion transmembrane transport	7/988	95/18722	0.235366202054799	0.408984385121064	CAV1/ITGB1/PTEN/FLNA/CRBN/WNK1/NEDD4	7
GO:0034250	positive regulation of cellular amide metabolic process	11/988	162/18722	0.236880276826394	0.410745635199965	VIM/ITGA2/THBS1/CLU/PABPC1/RHOA/PICALM/ROCK2/EIF4G2/MAPK1/CNBP	11
GO:0010039	response to iron ion	3/988	32/18722	0.237384996246968	0.410745635199965	B2M/HIF1A/CCND1	3
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	3/988	32/18722	0.237384996246968	0.410745635199965	MDK/CFLAR/RGL2	3
GO:0010743	regulation of macrophage derived foam cell differentiation	3/988	32/18722	0.237384996246968	0.410745635199965	PRKCH/CD36/ABCA1	3
GO:0019934	cGMP-mediated signaling	3/988	32/18722	0.237384996246968	0.410745635199965	NPR1/THBS1/CD36	3
GO:0035883	enteroendocrine cell differentiation	3/988	32/18722	0.237384996246968	0.410745635199965	CDK6/CLOCK/HES1	3
GO:0042044	fluid transport	3/988	32/18722	0.237384996246968	0.410745635199965	EDN1/HYAL2/ITPR1	3
GO:0048841	regulation of axon extension involved in axon guidance	3/988	32/18722	0.237384996246968	0.410745635199965	BMPR2/NRP1/SEMA3F	3
GO:0060914	heart formation	3/988	32/18722	0.237384996246968	0.410745635199965	MEF2C/NOTCH1/HES1	3
GO:0072525	pyridine-containing compound biosynthetic process	3/988	32/18722	0.237384996246968	0.410745635199965	NNMT/IDO1/PARP9	3
GO:0090140	regulation of mitochondrial fission	3/988	32/18722	0.237384996246968	0.410745635199965	KDR/DDHD1/RALA	3
GO:1900745	positive regulation of p38MAPK cascade	3/988	32/18722	0.237384996246968	0.410745635199965	SASH1/MAP3K3/PJA2	3
GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	3/988	32/18722	0.237384996246968	0.410745635199965	SERINC3/TMBIM6/HSPA1A	3
GO:0031343	positive regulation of cell killing	5/988	63/18722	0.238233245280606	0.412079126971858	HLA-E/HLA-A/HLA-B/B2M/LAMP1	5
GO:0006022	aminoglycan metabolic process	9/988	129/18722	0.241465899013267	0.417398911668882	NDNF/HYAL2/ANGPT1/PDGFB/CHSY1/TGFB1/GNS/CD44/B4GALT5	9
GO:0007093	mitotic cell cycle checkpoint signaling	9/988	129/18722	0.241465899013267	0.417398911668882	DUSP1/PML/TAOK1/APC/CCND1/WAC/ATF2/FOXN3/PLK2	9
GO:0046883	regulation of hormone secretion	16/988	249/18722	0.243127517673196	0.418538963594857	EDN1/CRHBP/P2RY1/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CREB1/CLOCK/PPP3CA/PIM3/MIDN/SMAD4	16
GO:0006637	acyl-CoA metabolic process	7/988	96/18722	0.243327812536747	0.418538963594857	PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A/FAR1	7
GO:0015914	phospholipid transport	7/988	96/18722	0.243327812536747	0.418538963594857	PLSCR4/SCARB1/ATP11A/SCARB2/OSBPL10/ABCA1/PLSCR1	7
GO:0035383	thioester metabolic process	7/988	96/18722	0.243327812536747	0.418538963594857	PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A/FAR1	7
GO:0002223	stimulatory C-type lectin receptor signaling pathway	2/988	18/18722	0.245198278371083	0.418538963594857	FYN/PAK2	2
GO:0002544	chronic inflammatory response	2/988	18/18722	0.245198278371083	0.418538963594857	THBS1/GJA1	2
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	2/988	18/18722	0.245198278371083	0.418538963594857	FCGR2B/CD46	2
GO:0003417	growth plate cartilage development	2/988	18/18722	0.245198278371083	0.418538963594857	TGFBR2/ZMPSTE24	2
GO:0006595	polyamine metabolic process	2/988	18/18722	0.245198278371083	0.418538963594857	NNMT/OAZ2	2
GO:0007549	dosage compensation	2/988	18/18722	0.245198278371083	0.418538963594857	XIST/PCGF5	2
GO:0010663	positive regulation of striated muscle cell apoptotic process	2/988	18/18722	0.245198278371083	0.418538963594857	PTEN/CAPN2	2
GO:0010666	positive regulation of cardiac muscle cell apoptotic process	2/988	18/18722	0.245198278371083	0.418538963594857	PTEN/CAPN2	2
GO:0015693	magnesium ion transport	2/988	18/18722	0.245198278371083	0.418538963594857	MAGT1/ZDHHC17	2
GO:0015732	prostaglandin transport	2/988	18/18722	0.245198278371083	0.418538963594857	EDN1/SLCO2A1	2
GO:0019896	axonal transport of mitochondrion	2/988	18/18722	0.245198278371083	0.418538963594857	ARMCX3/HIF1A	2
GO:0031643	positive regulation of myelination	2/988	18/18722	0.245198278371083	0.418538963594857	DICER1/TNFRSF1B	2
GO:0032769	negative regulation of monooxygenase activity	2/988	18/18722	0.245198278371083	0.418538963594857	CAV1/ATP2B4	2
GO:0034433	steroid esterification	2/988	18/18722	0.245198278371083	0.418538963594857	ACAT1/STARD4	2
GO:0034434	sterol esterification	2/988	18/18722	0.245198278371083	0.418538963594857	ACAT1/STARD4	2
GO:0034435	cholesterol esterification	2/988	18/18722	0.245198278371083	0.418538963594857	ACAT1/STARD4	2
GO:0035743	CD4-positive, alpha-beta T cell cytokine production	2/988	18/18722	0.245198278371083	0.418538963594857	IL1R1/CD81	2
GO:0042693	muscle cell fate commitment	2/988	18/18722	0.245198278371083	0.418538963594857	MEF2C/TBX3	2
GO:0044872	lipoprotein localization	2/988	18/18722	0.245198278371083	0.418538963594857	CD36/ZDHHC17	2
GO:0045116	protein neddylation	2/988	18/18722	0.245198278371083	0.418538963594857	EPAS1/HIF1A	2
GO:0045623	negative regulation of T-helper cell differentiation	2/988	18/18722	0.245198278371083	0.418538963594857	HLX/RC3H1	2
GO:0048535	lymph node development	2/988	18/18722	0.245198278371083	0.418538963594857	TGFB1/RC3H1	2
GO:0050665	hydrogen peroxide biosynthetic process	2/988	18/18722	0.245198278371083	0.418538963594857	FYN/STAT3	2
GO:0051382	kinetochore assembly	2/988	18/18722	0.245198278371083	0.418538963594857	POGZ/SENP6	2
GO:0055070	copper ion homeostasis	2/988	18/18722	0.245198278371083	0.418538963594857	APP/XIAP	2
GO:0071318	cellular response to ATP	2/988	18/18722	0.245198278371083	0.418538963594857	P2RY1/HSP90B1	2
GO:0071360	cellular response to exogenous dsRNA	2/988	18/18722	0.245198278371083	0.418538963594857	CAV1/RALB	2
GO:0071786	endoplasmic reticulum tubular network organization	2/988	18/18722	0.245198278371083	0.418538963594857	ATL3/RTN4	2
GO:0072189	ureter development	2/988	18/18722	0.245198278371083	0.418538963594857	NFIA/FOXF1	2
GO:0098877	neurotransmitter receptor transport to plasma membrane	2/988	18/18722	0.245198278371083	0.418538963594857	STX3/RAB11A	2
GO:0110154	RNA decapping	2/988	18/18722	0.245198278371083	0.418538963594857	NUDT3/ZFP36	2
GO:1900424	regulation of defense response to bacterium	2/988	18/18722	0.245198278371083	0.418538963594857	FOXP1/SYT11	2
GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus	2/988	18/18722	0.245198278371083	0.418538963594857	ADGRA2/ATP2B4	2
GO:1990840	response to lectin	2/988	18/18722	0.245198278371083	0.418538963594857	FYN/PAK2	2
GO:1990858	cellular response to lectin	2/988	18/18722	0.245198278371083	0.418538963594857	FYN/PAK2	2
GO:0043303	mast cell degranulation	4/988	48/18722	0.246545814281067	0.420703940077426	FOXF1/GATA2/SNAP23/S100A13	4
GO:0050864	regulation of B cell activation	13/988	198/18722	0.247501728352191	0.422199480092112	FCGR2B/MEF2C/AHR/CD81/ZFP36L1/PKN1/TGFB1/RC3H1/ZFP36L2/CD320/KMT5B/RIF1/ID2	13
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	5/988	64/18722	0.248194343625939	0.423109227644733	PRKCE/KIF5B/HIF1A/MAP4K4/PIM3	5
GO:1903018	regulation of glycoprotein metabolic process	5/988	64/18722	0.248194343625939	0.423109227644733	IGF1/IL33/ITM2A/PLCB1/ITM2B	5
GO:0001975	response to amphetamine	3/988	33/18722	0.251726879778957	0.426939075793685	CALM1/RANBP2/PPP3CA	3
GO:0010259	multicellular organism aging	3/988	33/18722	0.251726879778957	0.426939075793685	EDN1/HYAL2/ZMPSTE24	3
GO:0010737	protein kinase A signaling	3/988	33/18722	0.251726879778957	0.426939075793685	RAMP3/RDX/PJA2	3
GO:0019362	pyridine nucleotide metabolic process	3/988	33/18722	0.251726879778957	0.426939075793685	NNMT/IDO1/PARP9	3
GO:0031116	positive regulation of microtubule polymerization	3/988	33/18722	0.251726879778957	0.426939075793685	GIT1/HSPA1A/NIN	3
GO:0032228	regulation of synaptic transmission, GABAergic	3/988	33/18722	0.251726879778957	0.426939075793685	PRKCE/KIF5B/PTEN	3
GO:0033198	response to ATP	3/988	33/18722	0.251726879778957	0.426939075793685	P2RY1/PTEN/HSP90B1	3
GO:0040020	regulation of meiotic nuclear division	3/988	33/18722	0.251726879778957	0.426939075793685	RPS6KA2/PLCB1/PRKAR1A	3
GO:0046496	nicotinamide nucleotide metabolic process	3/988	33/18722	0.251726879778957	0.426939075793685	NNMT/IDO1/PARP9	3
GO:0071539	protein localization to centrosome	3/988	33/18722	0.251726879778957	0.426939075793685	BICD1/PCM1/APC	3
GO:1901099	negative regulation of signal transduction in absence of ligand	3/988	33/18722	0.251726879778957	0.426939075793685	FYN/CTNNA1/HSPA1A	3
GO:1901380	negative regulation of potassium ion transmembrane transport	3/988	33/18722	0.251726879778957	0.426939075793685	CAV1/PTEN/CRBN	3
GO:1903146	regulation of autophagy of mitochondrion	3/988	33/18722	0.251726879778957	0.426939075793685	HIF1A/CTTN/VPS13C	3
GO:1903715	regulation of aerobic respiration	3/988	33/18722	0.251726879778957	0.426939075793685	COX7A1/RHOA/HIF1A	3
GO:2000036	regulation of stem cell population maintenance	3/988	33/18722	0.251726879778957	0.426939075793685	LOXL2/CNOT2/SAV1	3
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	3/988	33/18722	0.251726879778957	0.426939075793685	FYN/CTNNA1/HSPA1A	3
GO:0007041	lysosomal transport	8/988	114/18722	0.254016982603003	0.430685672386578	RHOB/CLU/SCARB2/LYST/LAMP1/DTX3L/HSPA1A/NEDD4	8
GO:0050796	regulation of insulin secretion	11/988	165/18722	0.255160820562964	0.432487006646607	NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CLOCK/PPP3CA/PIM3/MIDN	11
GO:0000723	telomere maintenance	9/988	131/18722	0.255258705754474	0.432514910675524	PML/ATRX/HMBOX1/SP100/NEK7/SMG1/RIF1/MAPK1/XRN1	9
GO:0051817	modulation of process of other organism involved in symbiotic interaction	6/988	81/18722	0.255485633707195	0.432725363068693	IFI27/HYAL2/CAV2/STOM/JUN/CCNT1	6
GO:0044839	cell cycle G2/M phase transition	10/988	148/18722	0.255545832821252	0.432725363068693	PLCB1/APP/CCNY/CALM1/TAOK1/CDC25B/ARPP19/CCND1/RAB11A/FOXN3	10
GO:0002279	mast cell activation involved in immune response	4/988	49/18722	0.25825194298639	0.434963749335661	FOXF1/GATA2/SNAP23/S100A13	4
GO:0006376	mRNA splice site selection	4/988	49/18722	0.25825194298639	0.434963749335661	SETX/CELF1/LUC7L3/PSIP1	4
GO:0010823	negative regulation of mitochondrion organization	4/988	49/18722	0.25825194298639	0.434963749335661	IGF1/VAT1/CLU/HSPA1A	4
GO:0014075	response to amine	4/988	49/18722	0.25825194298639	0.434963749335661	ITGA2/CALM1/RANBP2/PPP3CA	4
GO:0046605	regulation of centrosome cycle	4/988	49/18722	0.25825194298639	0.434963749335661	PDCD6IP/ROCK2/XPO1/PLK2	4
GO:0048168	regulation of neuronal synaptic plasticity	4/988	49/18722	0.25825194298639	0.434963749335661	APP/NPTN/RAB11A/RAB5A	4
GO:0051932	synaptic transmission, GABAergic	4/988	49/18722	0.25825194298639	0.434963749335661	PRKCE/KIF5B/PTEN/CLCN3	4
GO:0070741	response to interleukin-6	4/988	49/18722	0.25825194298639	0.434963749335661	JAK1/IL6ST/STAT3/SMAD4	4
GO:0086009	membrane repolarization	4/988	49/18722	0.25825194298639	0.434963749335661	CAV1/FLNA/GJA5/ZMPSTE24	4
GO:1901799	negative regulation of proteasomal protein catabolic process	4/988	49/18722	0.25825194298639	0.434963749335661	OGT/RYBP/SDCBP/WAC	4
GO:1904894	positive regulation of receptor signaling pathway via STAT	4/988	49/18722	0.25825194298639	0.434963749335661	F2R/NOTCH1/TGFB1/HES1	4
GO:1990928	response to amino acid starvation	4/988	49/18722	0.25825194298639	0.434963749335661	SLC38A2/EIF2AK2/SH3GLB1/MAPK1	4
GO:0035418	protein localization to synapse	5/988	65/18722	0.258259726168049	0.434963749335661	KIF5B/STX3/ADAM10/RAB11A/RAP1A	5
GO:0046513	ceramide biosynthetic process	5/988	65/18722	0.258259726168049	0.434963749335661	SPTLC2/UGCG/ST3GAL5/PRKAA1/B4GALT5	5
GO:0048645	animal organ formation	5/988	65/18722	0.258259726168049	0.434963749335661	MEF2C/NOTCH1/TGFBR2/HES1/MAPK1	5
GO:0070936	protein K48-linked ubiquitination	5/988	65/18722	0.258259726168049	0.434963749335661	IFI27/HACE1/TTC3/DTX3L/UBE2E3	5
GO:0090307	mitotic spindle assembly	5/988	65/18722	0.258259726168049	0.434963749335661	FLNA/RHOA/STAG2/RAB11A/HSPA1A	5
GO:0032642	regulation of chemokine production	7/988	98/18722	0.259496784833793	0.436908691295438	IL33/FOXP1/APP/KLF4/HIF1A/EIF2AK2/EGR1	7
GO:0090630	activation of GTPase activity	8/988	115/18722	0.261517167728698	0.440170847583917	ARHGAP29/ARHGEF15/RALGAPA2/NEDD9/TBC1D4/TBC1D15/CRK/RALGAPB	8
GO:0006403	RNA localization	13/988	201/18722	0.264319793008166	0.441047428744592	BICD1/HHEX/TGFBR2/ZFP36L1/RANBP2/QKI/ZFP36/ZC3H11A/MYO1C/FYTTD1/THOC2/SMG1/XPO1	13
GO:0065004	protein-DNA complex assembly	13/988	201/18722	0.264319793008166	0.441047428744592	TCF4/THRA/RB1/ATRX/POGZ/CREB1/RSF1/ATF7IP/KAT6A/UBN2/PIAS1/BAZ2A/SENP6	13
GO:0009205	purine ribonucleoside triphosphate metabolic process	6/988	82/18722	0.264485232435789	0.441047428744592	GIMAP7/TMSB4X/TGFB1/RHOA/STAT3/ATP6V1A	6
GO:0002281	macrophage activation involved in immune response	2/988	19/18722	0.265151103857195	0.441047428744592	PRKCE/DYSF	2
GO:0002396	MHC protein complex assembly	2/988	19/18722	0.265151103857195	0.441047428744592	B2M/TAPBP	2
GO:0002523	leukocyte migration involved in inflammatory response	2/988	19/18722	0.265151103857195	0.441047428744592	MDK/JAM3	2
GO:0006491	N-glycan processing	2/988	19/18722	0.265151103857195	0.441047428744592	MGAT4A/MAN1A1	2
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2/988	19/18722	0.265151103857195	0.441047428744592	PML/PLK2	2
GO:0010738	regulation of protein kinase A signaling	2/988	19/18722	0.265151103857195	0.441047428744592	RAMP3/PJA2	2
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2/988	19/18722	0.265151103857195	0.441047428744592	PRKCH/CD36	2
GO:0010829	negative regulation of glucose transmembrane transport	2/988	19/18722	0.265151103857195	0.441047428744592	FABP5/PEA15	2
GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	2/988	19/18722	0.265151103857195	0.441047428744592	KLF4/PTEN	2
GO:0030011	maintenance of cell polarity	2/988	19/18722	0.265151103857195	0.441047428744592	DST/PDCD6IP	2
GO:0030220	platelet formation	2/988	19/18722	0.265151103857195	0.441047428744592	MEF2C/MYH9	2
GO:0031065	positive regulation of histone deacetylation	2/988	19/18722	0.265151103857195	0.441047428744592	APLNR/NIPBL	2
GO:0031290	retinal ganglion cell axon guidance	2/988	19/18722	0.265151103857195	0.441047428744592	NRP1/PTPRM	2
GO:0032026	response to magnesium ion	2/988	19/18722	0.265151103857195	0.441047428744592	THBS1/CCND1	2
GO:0033194	response to hydroperoxide	2/988	19/18722	0.265151103857195	0.441047428744592	TP53INP1/CD36	2
GO:0036344	platelet morphogenesis	2/988	19/18722	0.265151103857195	0.441047428744592	MEF2C/MYH9	2
GO:0042474	middle ear morphogenesis	2/988	19/18722	0.265151103857195	0.441047428744592	EDN1/TSHZ1	2
GO:0044827	modulation by host of viral genome replication	2/988	19/18722	0.265151103857195	0.441047428744592	IFI27/STOM	2
GO:0045618	positive regulation of keratinocyte differentiation	2/988	19/18722	0.265151103857195	0.441047428744592	NOTCH1/PRKCH	2
GO:0051546	keratinocyte migration	2/988	19/18722	0.265151103857195	0.441047428744592	PTEN/MAP4K4	2
GO:0051957	positive regulation of amino acid transport	2/988	19/18722	0.265151103857195	0.441047428744592	ITGB1/SLC12A2	2
GO:0071545	inositol phosphate catabolic process	2/988	19/18722	0.265151103857195	0.441047428744592	NUDT3/PTEN	2
GO:0072074	kidney mesenchyme development	2/988	19/18722	0.265151103857195	0.441047428744592	PKD2/SMAD4	2
GO:0140131	positive regulation of lymphocyte chemotaxis	2/988	19/18722	0.265151103857195	0.441047428744592	ADAM10/WNK1	2
GO:1900221	regulation of amyloid-beta clearance	2/988	19/18722	0.265151103857195	0.441047428744592	CLU/ROCK1	2
GO:1903204	negative regulation of oxidative stress-induced neuron death	2/988	19/18722	0.265151103857195	0.441047428744592	NCOA7/HIF1A	2
GO:2000369	regulation of clathrin-dependent endocytosis	2/988	19/18722	0.265151103857195	0.441047428744592	SYT11/WASL	2
GO:2000738	positive regulation of stem cell differentiation	2/988	19/18722	0.265151103857195	0.441047428744592	TCF15/LTBP3	2
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	2/988	19/18722	0.265151103857195	0.441047428744592	HLA-E/HLA-A	2
GO:0001662	behavioral fear response	3/988	34/18722	0.2661893931768	0.441047428744592	MEF2C/MDK/GJA1	3
GO:0014072	response to isoquinoline alkaloid	3/988	34/18722	0.2661893931768	0.441047428744592	PRKCE/PEA15/PPP2R2A	3
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3/988	34/18722	0.2661893931768	0.441047428744592	PDE4D/CLIC2/CALM1	3
GO:0019076	viral release from host cell	3/988	34/18722	0.2661893931768	0.441047428744592	CAV2/PML/TRIM13	3
GO:0030851	granulocyte differentiation	3/988	34/18722	0.2661893931768	0.441047428744592	CEACAM1/GATA2/LBR	3
GO:0032212	positive regulation of telomere maintenance via telomerase	3/988	34/18722	0.2661893931768	0.441047428744592	HMBOX1/NEK7/MAPK1	3
GO:0032743	positive regulation of interleukin-2 production	3/988	34/18722	0.2661893931768	0.441047428744592	SPTBN1/PDE4D/PDE4B	3
GO:0032770	positive regulation of monooxygenase activity	3/988	34/18722	0.2661893931768	0.441047428744592	SCARB1/CALM1/HIF1A	3
GO:0035890	exit from host	3/988	34/18722	0.2661893931768	0.441047428744592	CAV2/PML/TRIM13	3
GO:0035891	exit from host cell	3/988	34/18722	0.2661893931768	0.441047428744592	CAV2/PML/TRIM13	3
GO:0043278	response to morphine	3/988	34/18722	0.2661893931768	0.441047428744592	PRKCE/PEA15/PPP2R2A	3
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	3/988	34/18722	0.2661893931768	0.441047428744592	CD44/DYRK1A/ZMPSTE24	3
GO:0048261	negative regulation of receptor-mediated endocytosis	3/988	34/18722	0.2661893931768	0.441047428744592	SYT11/SDCBP/PICALM	3
GO:0051085	chaperone cofactor-dependent protein refolding	3/988	34/18722	0.2661893931768	0.441047428744592	ERO1A/HSPA1A/HSPH1	3
GO:0070232	regulation of T cell apoptotic process	3/988	34/18722	0.2661893931768	0.441047428744592	IDO1/GIMAP8/HIF1A	3
GO:0086019	cell-cell signaling involved in cardiac conduction	3/988	34/18722	0.2661893931768	0.441047428744592	GJA1/FLNA/GJA5	3
GO:0098751	bone cell development	3/988	34/18722	0.2661893931768	0.441047428744592	FLI1/FOXP1/SH2B3	3
GO:2000758	positive regulation of peptidyl-lysine acetylation	3/988	34/18722	0.2661893931768	0.441047428744592	PRKAA1/DIP2A/SMAD4	3
GO:0002444	myeloid leukocyte mediated immunity	7/988	99/18722	0.2676946456945	0.442988771940556	FCGR2B/FOXF1/HLA-E/KMT2E/GATA2/SNAP23/S100A13	7
GO:0032602	chemokine production	7/988	99/18722	0.2676946456945	0.442988771940556	IL33/FOXP1/APP/KLF4/HIF1A/EIF2AK2/EGR1	7
GO:0042100	B cell proliferation	7/988	99/18722	0.2676946456945	0.442988771940556	FCGR2B/MEF2C/AHR/CD81/PKN1/RC3H1/CD320	7
GO:0060291	long-term synaptic potentiation	7/988	99/18722	0.2676946456945	0.442988771940556	APP/STX3/PTEN/CREB1/NPTN/MAPK1/PLK2	7
GO:0042446	hormone biosynthetic process	5/988	66/18722	0.268420033527042	0.44377442206525	HSD17B2/SCARB1/HIF1A/HSD17B12/EGR1	5
GO:0045600	positive regulation of fat cell differentiation	5/988	66/18722	0.268420033527042	0.44377442206525	ZFP36L1/ZFP36/CREB1/ID2/SAV1	5
GO:2000272	negative regulation of signaling receptor activity	5/988	66/18722	0.268420033527042	0.44377442206525	CRHBP/RAMP3/PTEN/SOCS4/CBLB	5
GO:0006997	nucleus organization	9/988	133/18722	0.269299691660657	0.444951776703393	ETS1/HIPK2/PML/SUN1/MFSD14A/RTN4/PLEC/BAZ2A/ZMPSTE24	9
GO:0046887	positive regulation of hormone secretion	9/988	133/18722	0.269299691660657	0.444951776703393	EDN1/P2RY1/NNAT/PRKCE/KIF5B/GJA1/HIF1A/CREB1/SMAD4	9
GO:0002448	mast cell mediated immunity	4/988	50/18722	0.270064413238434	0.445245860683601	FOXF1/GATA2/SNAP23/S100A13	4
GO:0002639	positive regulation of immunoglobulin production	4/988	50/18722	0.270064413238434	0.445245860683601	HLA-E/TGFB1/KMT5B/RIF1	4
GO:0050873	brown fat cell differentiation	4/988	50/18722	0.270064413238434	0.445245860683601	FABP4/ADRB1/ERO1A/PLAC8	4
GO:0070231	T cell apoptotic process	4/988	50/18722	0.270064413238434	0.445245860683601	IDO1/GIMAP8/HIF1A/BCL10	4
GO:0090102	cochlea development	4/988	50/18722	0.270064413238434	0.445245860683601	DCHS1/ADAM10/GATA2/HES1	4
GO:0099054	presynapse assembly	4/988	50/18722	0.270064413238434	0.445245860683601	EFNB2/APP/PTEN/SDCBP	4
GO:1903747	regulation of establishment of protein localization to mitochondrion	4/988	50/18722	0.270064413238434	0.445245860683601	ABLIM3/LEPROT/PRKAA1/SH3GLB1	4
GO:1901292	nucleoside phosphate catabolic process	6/988	83/18722	0.273564313156387	0.450876087957408	NT5E/PDE4D/ENTPD1/NUDT3/PDE4B/ACAT1	6
GO:0071333	cellular response to glucose stimulus	10/988	151/18722	0.275399251334516	0.453759560511461	ZBTB20/PRKCE/KIF5B/LGALS1/PIK3CA/HIF1A/MAP4K4/PPP3CA/PIM3/PRKAA1	10
GO:0006643	membrane lipid metabolic process	13/988	203/18722	0.275746350550298	0.454190578022693	ENPP2/PLPP1/SPTLC2/UGCG/PRKD3/MGST2/ST3GAL5/SERINC3/SERINC1/PLPP3/ELOVL5/PRKAA1/B4GALT5	13
GO:0044728	DNA methylation or demethylation	7/988	100/18722	0.275961703292461	0.454404391782254	KMT2E/ATRX/PIK3CA/KMT2A/ATF7IP/BAZ2A/ZMPSTE24	7
GO:0032147	activation of protein kinase activity	9/988	134/18722	0.276405887171926	0.454994754464603	IGF1/ANGPT1/TGFBR2/RGCC/PDGFB/PIK3CA/EMP2/CCDC88A/WNK1	9
GO:0071478	cellular response to radiation	12/988	186/18722	0.27810105685596	0.457643374850947	HYAL2/IFI16/RHOB/TIMP1/CARD16/TP53INP1/POLK/EGR1/CLOCK/NIPBL/NEDD4/ZMPSTE24	12
GO:0006869	lipid transport	24/988	398/18722	0.278355507286959	0.457920239922058	EDN1/FABP4/LRP6/PLSCR4/CEACAM1/FZD4/CAV1/SLCO2A1/SCARB1/FABP5/THBS1/UGCG/CLU/ATP11A/SCARB2/OSBPL10/CPT1A/ACSL3/CD36/ABCA1/PLSCR1/SLC2A1/STARD4/PRKAA1	24
GO:0042130	negative regulation of T cell proliferation	5/988	67/18722	0.278665950596931	0.458147177211668	LRRC32/PRKAR1A/TNFRSF14/RC3H1/CBLB	5
GO:0048814	regulation of dendrite morphogenesis	5/988	67/18722	0.278665950596931	0.458147177211668	ID1/ACTR2/RAPGEF2/PPP3CA/NEDD4	5
GO:0000075	cell cycle checkpoint signaling	11/988	169/18722	0.280254331663506	0.459858818242482	DUSP1/PML/TAOK1/FEM1B/APC/CLOCK/CCND1/WAC/ATF2/FOXN3/PLK2	11
GO:0002209	behavioral defense response	3/988	35/18722	0.280745886212419	0.459858818242482	MEF2C/MDK/GJA1	3
GO:0006084	acetyl-CoA metabolic process	3/988	35/18722	0.280745886212419	0.459858818242482	PDK4/ACAT1/DIP2A	3
GO:0008608	attachment of spindle microtubules to kinetochore	3/988	35/18722	0.280745886212419	0.459858818242482	RB1/APC/CDC42	3
GO:0010664	negative regulation of striated muscle cell apoptotic process	3/988	35/18722	0.280745886212419	0.459858818242482	MDK/CFLAR/RGL2	3
GO:0010765	positive regulation of sodium ion transport	3/988	35/18722	0.280745886212419	0.459858818242482	KIF5B/ACTN4/WNK1	3
GO:0019068	virion assembly	3/988	35/18722	0.280745886212419	0.459858818242482	PDCD6IP/DDX6/NEDD4	3
GO:0031076	embryonic camera-type eye development	3/988	35/18722	0.280745886212419	0.459858818242482	HIPK2/PHACTR4/HIPK1	3
GO:0032350	regulation of hormone metabolic process	3/988	35/18722	0.280745886212419	0.459858818242482	HIF1A/EGR1/ZMPSTE24	3
GO:0046627	negative regulation of insulin receptor signaling pathway	3/988	35/18722	0.280745886212419	0.459858818242482	GRB14/SOCS3/PRKAA1	3
GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	3/988	35/18722	0.280745886212419	0.459858818242482	PDE4D/CLIC2/CALM1	3
GO:1905508	protein localization to microtubule organizing center	3/988	35/18722	0.280745886212419	0.459858818242482	BICD1/PCM1/APC	3
GO:0009948	anterior/posterior axis specification	4/988	51/18722	0.281968628323153	0.461538323383063	SKI/TBX3/ETS2/SMAD4	4
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	4/988	51/18722	0.281968628323153	0.461538323383063	CARD8/ZMYND11/RHOA/ASH1L	4
GO:0008643	carbohydrate transport	10/988	152/18722	0.282118775607079	0.461538323383063	EDN1/IGF1/FABP5/MEF2A/PEA15/YES1/ARPP19/SLC2A1/SLC2A3/RAP1A	10
GO:0016125	sterol metabolic process	10/988	152/18722	0.282118775607079	0.461538323383063	LEPR/SCARF1/SCARB1/APP/ABCA1/LBR/LIPA/PRKAA1/CYB5R3/NFE2L1	10
GO:0015931	nucleobase-containing compound transport	14/988	222/18722	0.284322783513473	0.462149012170771	HHEX/LRRC8C/TGFBR2/ZFP36L1/GJA1/RANBP2/QKI/ZFP36/ZC3H11A/MYO1C/FYTTD1/THOC2/SMG1/XPO1	14
GO:0007613	memory	8/988	118/18722	0.284395832751822	0.462149012170771	SYT11/PLCB1/RCAN1/MDK/PTEN/CREB1/PJA2/PLK2	8
GO:0030203	glycosaminoglycan metabolic process	8/988	118/18722	0.284395832751822	0.462149012170771	NDNF/HYAL2/ANGPT1/PDGFB/CHSY1/TGFB1/GNS/CD44	8
GO:0043270	positive regulation of ion transport	17/988	275/18722	0.285065761206931	0.462149012170771	APLNR/EDN1/RAMP3/P2RY1/F2R/CAV1/ITGB1/TMSB4X/KIF5B/PDGFB/ACTN4/SLC12A2/CALM1/STIM2/FLNA/PKD2/WNK1	17
GO:0002115	store-operated calcium entry	2/988	20/18722	0.285102092033813	0.462149012170771	SARAF/STIM2	2
GO:0002577	regulation of antigen processing and presentation	2/988	20/18722	0.285102092033813	0.462149012170771	FCGR2B/THBS1	2
GO:0002834	regulation of response to tumor cell	2/988	20/18722	0.285102092033813	0.462149012170771	CEACAM1/AHR	2
GO:0002837	regulation of immune response to tumor cell	2/988	20/18722	0.285102092033813	0.462149012170771	CEACAM1/AHR	2
GO:0003215	cardiac right ventricle morphogenesis	2/988	20/18722	0.285102092033813	0.462149012170771	JAG1/NOTCH1	2
GO:0006525	arginine metabolic process	2/988	20/18722	0.285102092033813	0.462149012170771	DDAH2/ATP2B4	2
GO:0010893	positive regulation of steroid biosynthetic process	2/988	20/18722	0.285102092033813	0.462149012170771	STARD4/PRKAA1	2
GO:0017121	plasma membrane phospholipid scrambling	2/988	20/18722	0.285102092033813	0.462149012170771	PLSCR4/PLSCR1	2
GO:0031645	negative regulation of nervous system process	2/988	20/18722	0.285102092033813	0.462149012170771	JAM2/PTEN	2
GO:0032332	positive regulation of chondrocyte differentiation	2/988	20/18722	0.285102092033813	0.462149012170771	ACVRL1/LOXL2	2
GO:0032930	positive regulation of superoxide anion generation	2/988	20/18722	0.285102092033813	0.462149012170771	GNAI2/TGFB1	2
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	2/988	20/18722	0.285102092033813	0.462149012170771	ITM2A/ITM2B	2
GO:0043555	regulation of translation in response to stress	2/988	20/18722	0.285102092033813	0.462149012170771	RPS6KA3/EIF2AK2	2
GO:0046485	ether lipid metabolic process	2/988	20/18722	0.285102092033813	0.462149012170771	AGPS/FAR1	2
GO:0046931	pore complex assembly	2/988	20/18722	0.285102092033813	0.462149012170771	ADAM10/RTN4	2
GO:0048025	negative regulation of mRNA splicing, via spliceosome	2/988	20/18722	0.285102092033813	0.462149012170771	DYRK1A/HNRNPK	2
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	2/988	20/18722	0.285102092033813	0.462149012170771	ISG15/ADAR	2
GO:0070932	histone H3 deacetylation	2/988	20/18722	0.285102092033813	0.462149012170771	HDAC7/ELK4	2
GO:0071397	cellular response to cholesterol	2/988	20/18722	0.285102092033813	0.462149012170771	LRP6/ABCA1	2
GO:0072567	chemokine (C-X-C motif) ligand 2 production	2/988	20/18722	0.285102092033813	0.462149012170771	FOXP1/KLF4	2
GO:0090201	negative regulation of release of cytochrome c from mitochondria	2/988	20/18722	0.285102092033813	0.462149012170771	IGF1/CLU	2
GO:0097503	sialylation	2/988	20/18722	0.285102092033813	0.462149012170771	ST6GAL1/ST3GAL5	2
GO:0098543	detection of other organism	2/988	20/18722	0.285102092033813	0.462149012170771	HLA-A/HLA-B	2
GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	2/988	20/18722	0.285102092033813	0.462149012170771	TMBIM6/HSPA1A	2
GO:1904292	regulation of ERAD pathway	2/988	20/18722	0.285102092033813	0.462149012170771	CAV1/ATXN3	2
GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	2/988	20/18722	0.285102092033813	0.462149012170771	FOXP1/KLF4	2
GO:0071331	cellular response to hexose stimulus	10/988	153/18722	0.288885046640684	0.467592284120023	ZBTB20/PRKCE/KIF5B/LGALS1/PIK3CA/HIF1A/MAP4K4/PPP3CA/PIM3/PRKAA1	10
GO:0007585	respiratory gaseous exchange by respiratory system	5/988	68/18722	0.288988228306859	0.467592284120023	EDN1/DACH1/TCF15/GLS/CSF2RB	5
GO:0042698	ovulation cycle	5/988	68/18722	0.288988228306859	0.467592284120023	FZD4/ETS1/PAM/MDK/EGR1	5
GO:0046686	response to cadmium ion	5/988	68/18722	0.288988228306859	0.467592284120023	SPARC/B2M/SLC30A1/MAPK1/JUN	5
GO:1901016	regulation of potassium ion transmembrane transporter activity	5/988	68/18722	0.288988228306859	0.467592284120023	CAV1/ITGB1/PTEN/CRBN/NEDD4	5
GO:1901607	alpha-amino acid biosynthetic process	5/988	68/18722	0.288988228306859	0.467592284120023	SERINC3/GLS/MRI1/PLOD2/ATP2B4	5
GO:0007548	sex differentiation	17/988	276/18722	0.290082893090865	0.469220562758427	HOXA13/DACH1/FZD4/TNFSF10/ADAM15/SMAD5/ATRX/FLNA/RNF38/FNDC3A/CSDE1/NR2F2/TBX3/CTNNA1/CCND1/NIPBL/SMAD4	17
GO:0097006	regulation of plasma lipoprotein particle levels	6/988	85/18722	0.291934988509871	0.471919238784862	SCARB1/ACSL3/CD36/ABCA1/LIPA/HNRNPK	6
GO:0097194	execution phase of apoptosis	6/988	85/18722	0.291934988509871	0.471919238784862	DLC1/DICER1/TAOK1/CFLAR/PLSCR1/PAK2	6
GO:0071824	protein-DNA complex subunit organization	15/988	241/18722	0.292017797041763	0.471919238784862	TCF4/THRA/RB1/ATRX/POGZ/CREB1/RSF1/ATF7IP/KAT6A/UBN2/BPTF/PIAS1/ARID1A/BAZ2A/SENP6	15
GO:0070588	calcium ion transmembrane transport	19/988	312/18722	0.292387191811074	0.472372494799399	APLNR/RAMP3/F2R/PDE4D/ITPR1/CLIC2/FKBP1A/PRKCE/CALM1/FYN/SESTD1/STIM2/PDE4B/ERO1A/ITPR2/AHNAK/PKD2/ATP2B4/SEC61A1	19
GO:0006672	ceramide metabolic process	7/988	102/18722	0.292684134262608	0.472564778481147	PLPP1/SPTLC2/UGCG/ST3GAL5/PLPP3/PRKAA1/B4GALT5	7
GO:0032677	regulation of interleukin-8 production	7/988	102/18722	0.292684134262608	0.472564778481147	F2R/HYAL2/TMSB4X/KLF4/STAT3/HSPA1A/BCL10	7
GO:0034204	lipid translocation	4/988	52/18722	0.293950269261834	0.47446485272527	PLSCR4/ATP11A/ABCA1/PLSCR1	4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	3/988	36/18722	0.29537081002119	0.475601619530937	FCGR2B/THBS1/B2M	3
GO:0043949	regulation of cAMP-mediated signaling	3/988	36/18722	0.29537081002119	0.475601619530937	APLNR/PDE4D/RAPGEF2	3
GO:0045191	regulation of isotype switching	3/988	36/18722	0.29537081002119	0.475601619530937	TGFB1/KMT5B/RIF1	3
GO:0045652	regulation of megakaryocyte differentiation	3/988	36/18722	0.29537081002119	0.475601619530937	MEF2C/GABPA/GATA2	3
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	3/988	36/18722	0.29537081002119	0.475601619530937	HIP1/CCDC88A/SOS1	3
GO:0051385	response to mineralocorticoid	3/988	36/18722	0.29537081002119	0.475601619530937	EDN1/CALM1/CCND1	3
GO:0070306	lens fiber cell differentiation	3/988	36/18722	0.29537081002119	0.475601619530937	VIM/SKIL/ABI2	3
GO:0090322	regulation of superoxide metabolic process	3/988	36/18722	0.29537081002119	0.475601619530937	GNAI2/TGFB1/CD36	3
GO:0016052	carbohydrate catabolic process	10/988	154/18722	0.295695567716758	0.475836066559049	IGF1/ZBTB20/GIT1/APP/SCARB2/HIF1A/OGT/STAT3/RB1CC1/PRKAA1	10
GO:0071326	cellular response to monosaccharide stimulus	10/988	154/18722	0.295695567716758	0.475836066559049	ZBTB20/PRKCE/KIF5B/LGALS1/PIK3CA/HIF1A/MAP4K4/PPP3CA/PIM3/PRKAA1	10
GO:0002790	peptide secretion	15/988	242/18722	0.297438449219279	0.478495772941493	EDN1/CRHBP/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/ABCA1/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	15
GO:0008203	cholesterol metabolic process	9/988	137/18722	0.298031309005048	0.479304363740483	LEPR/SCARF1/SCARB1/APP/ABCA1/LBR/PRKAA1/CYB5R3/NFE2L1	9
GO:0001678	cellular glucose homeostasis	11/988	172/18722	0.299542625006167	0.481443396076478	ZBTB20/FOXO1/PRKCE/KIF5B/LGALS1/PIK3CA/HIF1A/MAP4K4/PPP3CA/PIM3/PRKAA1	11
GO:1901136	carbohydrate derivative catabolic process	11/988	172/18722	0.299542625006167	0.481443396076478	NT5E/HYAL2/PDE4D/TGFB1/GNS/NUDT3/PDE4B/EDEM3/ACAT1/MAN1A1/CD44	11
GO:0032411	positive regulation of transporter activity	8/988	120/18722	0.299925972221042	0.481913721850628	TMSB4X/KIF5B/ACTN4/CALM1/STIM2/KMT2A/PKD2/WNK1	8
GO:0019233	sensory perception of pain	7/988	103/18722	0.30112985192457	0.483543950555701	EDN1/P2RY1/ITGA2/F2R/FABP5/FYN/MAPK1	7
GO:0032637	interleukin-8 production	7/988	103/18722	0.30112985192457	0.483543950555701	F2R/HYAL2/TMSB4X/KLF4/STAT3/HSPA1A/BCL10	7
GO:0045921	positive regulation of exocytosis	6/988	86/18722	0.301213654440665	0.483543950555701	LAMP1/RAB27A/SDCBP/GATA2/PDCD6IP/RAB5A	6
GO:0006836	neurotransmitter transport	13/988	208/18722	0.304975010784264	0.486090112006595	P2RY1/MEF2C/SYT11/SLC38A2/ITGB1/GIT1/CALM1/STX3/SLC30A1/SNAP23/CTBP2/RAB5A/RAP1A	13
GO:0000002	mitochondrial genome maintenance	2/988	21/18722	0.304995923064379	0.486090112006595	MEF2A/AKT3	2
GO:0001502	cartilage condensation	2/988	21/18722	0.304995923064379	0.486090112006595	MGP/THRA	2
GO:0003091	renal water homeostasis	2/988	21/18722	0.304995923064379	0.486090112006595	HYAL2/AKAP11	2
GO:0006353	DNA-templated transcription, termination	2/988	21/18722	0.304995923064379	0.486090112006595	SETX/ZMPSTE24	2
GO:0006925	inflammatory cell apoptotic process	2/988	21/18722	0.304995923064379	0.486090112006595	MEF2C/ZMPSTE24	2
GO:0009067	aspartate family amino acid biosynthetic process	2/988	21/18722	0.304995923064379	0.486090112006595	MRI1/PLOD2	2
GO:0019985	translesion synthesis	2/988	21/18722	0.304995923064379	0.486090112006595	REV3L/POLK	2
GO:0023019	signal transduction involved in regulation of gene expression	2/988	21/18722	0.304995923064379	0.486090112006595	P2RY1/SMAD2	2
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	2/988	21/18722	0.304995923064379	0.486090112006595	STX3/SNAP23	2
GO:0032288	myelin assembly	2/988	21/18722	0.304995923064379	0.486090112006595	DICER1/CD9	2
GO:0033630	positive regulation of cell adhesion mediated by integrin	2/988	21/18722	0.304995923064379	0.486090112006595	PODXL/PIEZO1	2
GO:0035330	regulation of hippo signaling	2/988	21/18722	0.304995923064379	0.486090112006595	WWC2/WWC3	2
GO:0046885	regulation of hormone biosynthetic process	2/988	21/18722	0.304995923064379	0.486090112006595	HIF1A/EGR1	2
GO:0048485	sympathetic nervous system development	2/988	21/18722	0.304995923064379	0.486090112006595	NRP1/SEMA3F	2
GO:0048714	positive regulation of oligodendrocyte differentiation	2/988	21/18722	0.304995923064379	0.486090112006595	MDK/TNFRSF1B	2
GO:0048745	smooth muscle tissue development	2/988	21/18722	0.304995923064379	0.486090112006595	ENG/PKD2	2
GO:0051152	positive regulation of smooth muscle cell differentiation	2/988	21/18722	0.304995923064379	0.486090112006595	ENG/PIAS1	2
GO:0060445	branching involved in salivary gland morphogenesis	2/988	21/18722	0.304995923064379	0.486090112006595	PLXND1/NRP1	2
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	2/988	21/18722	0.304995923064379	0.486090112006595	CD36/BCL10	2
GO:0098856	intestinal lipid absorption	2/988	21/18722	0.304995923064379	0.486090112006595	UGCG/CD36	2
GO:0099500	vesicle fusion to plasma membrane	2/988	21/18722	0.304995923064379	0.486090112006595	STX3/SNAP23	2
GO:1902473	regulation of protein localization to synapse	2/988	21/18722	0.304995923064379	0.486090112006595	ADAM10/RAP1A	2
GO:2000291	regulation of myoblast proliferation	2/988	21/18722	0.304995923064379	0.486090112006595	MALAT1/ATF2	2
GO:0007224	smoothened signaling pathway	9/988	138/18722	0.305331959738736	0.486479715096631	FOXF1/TGFBR2/HIPK2/RB1/CHSY1/HIPK1/CTNNA1/WDR11/HES1	9
GO:0032210	regulation of telomere maintenance via telomerase	4/988	53/18722	0.305995326469577	0.486806581074092	HMBOX1/NEK7/MAPK1/XRN1	4
GO:0034381	plasma lipoprotein particle clearance	4/988	53/18722	0.305995326469577	0.486806581074092	SCARB1/CD36/LIPA/HNRNPK	4
GO:0045806	negative regulation of endocytosis	4/988	53/18722	0.305995326469577	0.486806581074092	CAV1/SYT11/SDCBP/PICALM	4
GO:0097479	synaptic vesicle localization	4/988	53/18722	0.305995326469577	0.486806581074092	KIF5B/PTEN/RAB27A/PICALM	4
GO:0099172	presynapse organization	4/988	53/18722	0.305995326469577	0.486806581074092	EFNB2/APP/PTEN/SDCBP	4
GO:0002224	toll-like receptor signaling pathway	8/988	121/18722	0.30776305291298	0.489472256608908	CAV1/PRKCE/RPS6KA3/CD36/RTN4/WDFY1/PJA2/BCL10	8
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	7/988	104/18722	0.309625471085649	0.491474526408858	EDN1/S1PR1/P2RY1/BICD1/F2R/LPAR6/GNB1	7
GO:0003407	neural retina development	5/988	70/18722	0.309825320596355	0.491474526408858	TSPAN12/HIPK2/PTPRM/ATP2B4/HIPK1	5
GO:0031112	positive regulation of microtubule polymerization or depolymerization	3/988	37/18722	0.31003974736372	0.491474526408858	GIT1/HSPA1A/NIN	3
GO:0031646	positive regulation of nervous system process	3/988	37/18722	0.31003974736372	0.491474526408858	ITGA2/DICER1/TNFRSF1B	3
GO:0033260	nuclear DNA replication	3/988	37/18722	0.31003974736372	0.491474526408858	DACH1/ATRX/ZMPSTE24	3
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	3/988	37/18722	0.31003974736372	0.491474526408858	THBS1/SULF2/NPTN	3
GO:0048846	axon extension involved in axon guidance	3/988	37/18722	0.31003974736372	0.491474526408858	BMPR2/NRP1/SEMA3F	3
GO:0051294	establishment of spindle orientation	3/988	37/18722	0.31003974736372	0.491474526408858	ITGB1/GJA1/MAP4	3
GO:1900077	negative regulation of cellular response to insulin stimulus	3/988	37/18722	0.31003974736372	0.491474526408858	GRB14/SOCS3/PRKAA1	3
GO:1902284	neuron projection extension involved in neuron projection guidance	3/988	37/18722	0.31003974736372	0.491474526408858	BMPR2/NRP1/SEMA3F	3
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	3/988	37/18722	0.31003974736372	0.491474526408858	HMBOX1/NEK7/MAPK1	3
GO:0019915	lipid storage	6/988	87/18722	0.310545969485641	0.492130128254095	CAV1/SCARB1/CPT1A/CD36/ABCA1/STARD4	6
GO:0098657	import into cell	14/988	227/18722	0.312588026007374	0.495218489159311	RAMP3/LRRC8C/THBS1/ITGB1/SLC12A2/FYN/ACSL3/CD36/SLC30A1/SLC2A1/ATP2B4/SLC2A3/WNK1/SLC16A2	14
GO:0051928	positive regulation of calcium ion transport	8/988	122/18722	0.315643105137861	0.499760409684744	APLNR/RAMP3/F2R/CAV1/PDGFB/CALM1/STIM2/PKD2	8
GO:1990266	neutrophil migration	8/988	122/18722	0.315643105137861	0.499760409684744	PECAM1/EDN1/ITGA1/IL1R1/MDK/JAM3/PDE4B/MOSPD2	8
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	4/988	54/18722	0.318090127847372	0.503155330530004	APLNR/ACVRL1/THBS1/GATA2	4
GO:0007215	glutamate receptor signaling pathway	4/988	54/18722	0.318090127847372	0.503155330530004	PLCB1/APP/GNAQ/FYN	4
GO:0086002	cardiac muscle cell action potential involved in contraction	4/988	54/18722	0.318090127847372	0.503155330530004	CAV1/GJA1/FLNA/GJA5	4
GO:2001022	positive regulation of response to DNA damage stimulus	7/988	105/18722	0.318166181334767	0.503155330530004	SKIL/SLF2/ACTR2/PARP9/DTX3L/KMT5B/RIF1	7
GO:0009144	purine nucleoside triphosphate metabolic process	6/988	88/18722	0.319925560801183	0.505787077076156	GIMAP7/TMSB4X/TGFB1/RHOA/STAT3/ATP6V1A	6
GO:0015748	organophosphate ester transport	9/988	140/18722	0.320053223573669	0.505811899332378	PLSCR4/LRRC8C/SCARB1/ATP11A/SCARB2/OSBPL10/GJA1/ABCA1/PLSCR1	9
GO:0015833	peptide transport	16/988	264/18722	0.320196487300158	0.505811899332378	EDN1/CRHBP/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/ABCA1/TAPBP/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	16
GO:0008344	adult locomotory behavior	5/988	71/18722	0.320322144080218	0.505811899332378	PREX2/HIPK2/APP/CLCN3/ZMPSTE24	5
GO:0032722	positive regulation of chemokine production	5/988	71/18722	0.320322144080218	0.505811899332378	IL33/APP/HIF1A/EIF2AK2/EGR1	5
GO:0042180	cellular ketone metabolic process	13/988	211/18722	0.322903633883133	0.507575133510688	IDO1/CEACAM1/CAV1/PRKCE/FABP5/PDK4/CPT1A/LPGAT1/ELOVL5/GLO1/EGR1/ATP2B4/STARD4	13
GO:0042491	inner ear auditory receptor cell differentiation	3/988	38/18722	0.324729432849593	0.507575133510688	JAG1/NOTCH1/HES1	3
GO:0051930	regulation of sensory perception of pain	3/988	38/18722	0.324729432849593	0.507575133510688	EDN1/F2R/FABP5	3
GO:0072524	pyridine-containing compound metabolic process	3/988	38/18722	0.324729432849593	0.507575133510688	NNMT/IDO1/PARP9	3
GO:0072538	T-helper 17 type immune response	3/988	38/18722	0.324729432849593	0.507575133510688	NOTCH1/STAT3/RC3H1	3
GO:0099622	cardiac muscle cell membrane repolarization	3/988	38/18722	0.324729432849593	0.507575133510688	FLNA/GJA5/ZMPSTE24	3
GO:0002053	positive regulation of mesenchymal cell proliferation	2/988	22/18722	0.324783109714388	0.507575133510688	FOXF1/TGFBR2	2
GO:0002220	innate immune response activating cell surface receptor signaling pathway	2/988	22/18722	0.324783109714388	0.507575133510688	FYN/PAK2	2
GO:0006662	glycerol ether metabolic process	2/988	22/18722	0.324783109714388	0.507575133510688	AGPS/FAR1	2
GO:0007398	ectoderm development	2/988	22/18722	0.324783109714388	0.507575133510688	ITGA6/ETS2	2
GO:0007413	axonal fasciculation	2/988	22/18722	0.324783109714388	0.507575133510688	NRP1/RTN4	2
GO:0009190	cyclic nucleotide biosynthetic process	2/988	22/18722	0.324783109714388	0.507575133510688	ADCY4/NPR1	2
GO:0010310	regulation of hydrogen peroxide metabolic process	2/988	22/18722	0.324783109714388	0.507575133510688	FYN/STAT3	2
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	2/988	22/18722	0.324783109714388	0.507575133510688	CLIC2/CALM1	2
GO:0014821	phasic smooth muscle contraction	2/988	22/18722	0.324783109714388	0.507575133510688	EDN1/TBX3	2
GO:0032402	melanosome transport	2/988	22/18722	0.324783109714388	0.507575133510688	RAB27A/RAB11A	2
GO:0032693	negative regulation of interleukin-10 production	2/988	22/18722	0.324783109714388	0.507575133510688	FCGR2B/TRIB2	2
GO:0032816	positive regulation of natural killer cell activation	2/988	22/18722	0.324783109714388	0.507575133510688	HLA-E/LAMP1	2
GO:0034629	cellular protein-containing complex localization	2/988	22/18722	0.324783109714388	0.507575133510688	RALB/WASL	2
GO:0035268	protein mannosylation	2/988	22/18722	0.324783109714388	0.507575133510688	DPY19L4/TMTC3	2
GO:0035357	peroxisome proliferator activated receptor signaling pathway	2/988	22/18722	0.324783109714388	0.507575133510688	FABP5/ACTN4	2
GO:0035584	calcium-mediated signaling using intracellular calcium source	2/988	22/18722	0.324783109714388	0.507575133510688	KDR/SELP	2
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	2/988	22/18722	0.324783109714388	0.507575133510688	HLX/RC3H1	2
GO:0046628	positive regulation of insulin receptor signaling pathway	2/988	22/18722	0.324783109714388	0.507575133510688	IGF2/GNAI2	2
GO:0050860	negative regulation of T cell receptor signaling pathway	2/988	22/18722	0.324783109714388	0.507575133510688	CEACAM1/CBLB	2
GO:0051412	response to corticosterone	2/988	22/18722	0.324783109714388	0.507575133510688	CALM1/CCND1	2
GO:0052652	cyclic purine nucleotide metabolic process	2/988	22/18722	0.324783109714388	0.507575133510688	ADCY4/NPR1	2
GO:0055093	response to hyperoxia	2/988	22/18722	0.324783109714388	0.507575133510688	CAV1/FOXO1	2
GO:0060444	branching involved in mammary gland duct morphogenesis	2/988	22/18722	0.324783109714388	0.507575133510688	PML/TBX3	2
GO:0071359	cellular response to dsRNA	2/988	22/18722	0.324783109714388	0.507575133510688	CAV1/RALB	2
GO:0090280	positive regulation of calcium ion import	2/988	22/18722	0.324783109714388	0.507575133510688	RAMP3/PDGFB	2
GO:0099563	modification of synaptic structure	2/988	22/18722	0.324783109714388	0.507575133510688	RHOA/CDC42	2
GO:0106030	neuron projection fasciculation	2/988	22/18722	0.324783109714388	0.507575133510688	NRP1/RTN4	2
GO:1900543	negative regulation of purine nucleotide metabolic process	2/988	22/18722	0.324783109714388	0.507575133510688	GIT1/STAT3	2
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/988	22/18722	0.324783109714388	0.507575133510688	APLNR/GATA2	2
GO:0009199	ribonucleoside triphosphate metabolic process	6/988	89/18722	0.329346112196011	0.514554867054474	GIMAP7/TMSB4X/TGFB1/RHOA/STAT3/ATP6V1A	6
GO:0002067	glandular epithelial cell differentiation	4/988	55/18722	0.330221363482334	0.515316064282655	NOTCH1/CDK6/CLOCK/HES1	4
GO:0045620	negative regulation of lymphocyte differentiation	4/988	55/18722	0.330221363482334	0.515316064282655	HLX/MDK/RC3H1/ID2	4
GO:0046164	alcohol catabolic process	4/988	55/18722	0.330221363482334	0.515316064282655	SCARF1/SCARB1/NUDT3/PTEN	4
GO:0051898	negative regulation of protein kinase B signaling	4/988	55/18722	0.330221363482334	0.515316064282655	HYAL2/SH2B3/KLF4/PTEN	4
GO:0032729	positive regulation of interferon-gamma production	5/988	72/18722	0.330859380120714	0.516008522372646	PDE4D/IL1R1/HLA-A/PDE4B/ISG15	5
GO:1905818	regulation of chromosome separation	5/988	72/18722	0.330859380120714	0.516008522372646	RB1/DUSP1/PLSCR1/APC/CDC27	5
GO:0071466	cellular response to xenobiotic stimulus	11/988	177/18722	0.332412712474756	0.518278934154947	EDN1/CRHBP/MEF2C/AHR/PPM1F/RB1/PDE4B/ABCA1/PRKAA1/PPP1R12A/RAP1A	11
GO:0030073	insulin secretion	12/988	195/18722	0.333924829633147	0.520483772010352	NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	12
GO:0046467	membrane lipid biosynthetic process	9/988	142/18722	0.334914041335719	0.521872510289041	PLPP1/SPTLC2/UGCG/PRKD3/ST3GAL5/PLPP3/ELOVL5/PRKAA1/B4GALT5	9
GO:0034644	cellular response to UV	6/988	90/18722	0.338801374357383	0.526706208651909	HYAL2/TIMP1/CARD16/TP53INP1/POLK/NEDD4	6
GO:0045638	negative regulation of myeloid cell differentiation	6/988	90/18722	0.338801374357383	0.526706208651909	CEACAM1/ZFP36L1/CDK6/GABPA/ZFP36/GATA2	6
GO:0035725	sodium ion transmembrane transport	11/988	178/18722	0.339075851057852	0.526706208651909	PRKCE/UTRN/KIF5B/STOM/ACTN4/SLC12A2/PKD2/FXYD5/ATP2B4/WNK1/NEDD4	11
GO:0016572	histone phosphorylation	3/988	39/18722	0.339417764294425	0.526706208651909	PKN1/PRKAA1/ZMPSTE24	3
GO:0017158	regulation of calcium ion-dependent exocytosis	3/988	39/18722	0.339417764294425	0.526706208651909	SYT11/NOTCH1/GNAI2	3
GO:0043267	negative regulation of potassium ion transport	3/988	39/18722	0.339417764294425	0.526706208651909	CAV1/PTEN/CRBN	3
GO:0045823	positive regulation of heart contraction	3/988	39/18722	0.339417764294425	0.526706208651909	EDN1/PDE4D/ADRB1	3
GO:0045923	positive regulation of fatty acid metabolic process	3/988	39/18722	0.339417764294425	0.526706208651909	CPT1A/LPGAT1/ELOVL5	3
GO:0051084	'de novo' posttranslational protein folding	3/988	39/18722	0.339417764294425	0.526706208651909	ERO1A/HSPA1A/HSPH1	3
GO:0051931	regulation of sensory perception	3/988	39/18722	0.339417764294425	0.526706208651909	EDN1/F2R/FABP5	3
GO:0090224	regulation of spindle organization	3/988	39/18722	0.339417764294425	0.526706208651909	DYNC1H1/HSPA1A/SENP6	3
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	3/988	39/18722	0.339417764294425	0.526706208651909	CALM1/STIM2/PKD2	3
GO:1902742	apoptotic process involved in development	3/988	39/18722	0.339417764294425	0.526706208651909	NOTCH1/TNFRSF1B/ATF2	3
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	3/988	39/18722	0.339417764294425	0.526706208651909	HLX/TGFBR2/CD81	3
GO:2000027	regulation of animal organ morphogenesis	8/988	125/18722	0.339503399552736	0.526706208651909	CD34/EDN1/RSPO3/SMURF2/RHOA/FZD6/DAAM1/CDC42	8
GO:0090276	regulation of peptide hormone secretion	12/988	196/18722	0.340277238758758	0.527752610886575	CRHBP/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CLOCK/PPP3CA/PIM3/MIDN	12
GO:0009166	nucleotide catabolic process	5/988	73/18722	0.341428389060294	0.528162984910969	NT5E/PDE4D/NUDT3/PDE4B/ACAT1	5
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	5/988	73/18722	0.341428389060294	0.528162984910969	PRKCE/KIF5B/HIF1A/MAP4K4/PIM3	5
GO:0051298	centrosome duplication	5/988	73/18722	0.341428389060294	0.528162984910969	PKD2/PDCD6IP/ROCK2/XPO1/PLK2	5
GO:0002090	regulation of receptor internalization	4/988	56/18722	0.342376107132498	0.528162984910969	ANGPT1/SDCBP/MKLN1/PPP3R1	4
GO:0002886	regulation of myeloid leukocyte mediated immunity	4/988	56/18722	0.342376107132498	0.528162984910969	FCGR2B/FOXF1/HLA-E/GATA2	4
GO:0006687	glycosphingolipid metabolic process	4/988	56/18722	0.342376107132498	0.528162984910969	UGCG/ST3GAL5/PRKAA1/B4GALT5	4
GO:0015800	acidic amino acid transport	4/988	56/18722	0.342376107132498	0.528162984910969	LRRC8C/ITGB1/SLC12A2/GJA1	4
GO:0051784	negative regulation of nuclear division	4/988	56/18722	0.342376107132498	0.528162984910969	RPS6KA2/DUSP1/PRKAR1A/APC	4
GO:0055078	sodium ion homeostasis	4/988	56/18722	0.342376107132498	0.528162984910969	EDN1/NPR1/GNAI2/SLC12A2	4
GO:0001919	regulation of receptor recycling	2/988	23/18722	0.344419536847063	0.528162984910969	RAMP3/ECE1	2
GO:0002082	regulation of oxidative phosphorylation	2/988	23/18722	0.344419536847063	0.528162984910969	COX7A1/RHOA	2
GO:0002363	alpha-beta T cell lineage commitment	2/988	23/18722	0.344419536847063	0.528162984910969	RHOA/STAT3	2
GO:0002758	innate immune response-activating signal transduction	2/988	23/18722	0.344419536847063	0.528162984910969	FYN/PAK2	2
GO:0003283	atrial septum development	2/988	23/18722	0.344419536847063	0.528162984910969	BMPR2/GJA5	2
GO:0003323	type B pancreatic cell development	2/988	23/18722	0.344419536847063	0.528162984910969	CDK6/CLOCK	2
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	2/988	23/18722	0.344419536847063	0.528162984910969	CARD16/CARD8	2
GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	2/988	23/18722	0.344419536847063	0.528162984910969	CLDN5/CLDN11	2
GO:0030325	adrenal gland development	2/988	23/18722	0.344419536847063	0.528162984910969	MDK/SMAD2	2
GO:0030539	male genitalia development	2/988	23/18722	0.344419536847063	0.528162984910969	HOXA13/TBX3	2
GO:0031338	regulation of vesicle fusion	2/988	23/18722	0.344419536847063	0.528162984910969	KIF5B/TBC1D4	2
GO:0032401	establishment of melanosome localization	2/988	23/18722	0.344419536847063	0.528162984910969	RAB27A/RAB11A	2
GO:0033081	regulation of T cell differentiation in thymus	2/988	23/18722	0.344419536847063	0.528162984910969	SOS2/SOS1	2
GO:0035640	exploration behavior	2/988	23/18722	0.344419536847063	0.528162984910969	PRKCE/CRBN	2
GO:0040019	positive regulation of embryonic development	2/988	23/18722	0.344419536847063	0.528162984910969	PLCB1/B4GALT5	2
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	2/988	23/18722	0.344419536847063	0.528162984910969	NEDD4/VPS36	2
GO:0045723	positive regulation of fatty acid biosynthetic process	2/988	23/18722	0.344419536847063	0.528162984910969	LPGAT1/ELOVL5	2
GO:0045932	negative regulation of muscle contraction	2/988	23/18722	0.344419536847063	0.528162984910969	CALCRL/DOCK4	2
GO:0045980	negative regulation of nucleotide metabolic process	2/988	23/18722	0.344419536847063	0.528162984910969	GIT1/STAT3	2
GO:0051131	chaperone-mediated protein complex assembly	2/988	23/18722	0.344419536847063	0.528162984910969	CLU/HSPA1A	2
GO:0051383	kinetochore organization	2/988	23/18722	0.344419536847063	0.528162984910969	POGZ/SENP6	2
GO:0051446	positive regulation of meiotic cell cycle	2/988	23/18722	0.344419536847063	0.528162984910969	PLCB1/CDC25B	2
GO:0051904	pigment granule transport	2/988	23/18722	0.344419536847063	0.528162984910969	RAB27A/RAB11A	2
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	2/988	23/18722	0.344419536847063	0.528162984910969	EHD2/CAPN2	2
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	2/988	23/18722	0.344419536847063	0.528162984910969	GJA5/ZMPSTE24	2
GO:0060384	innervation	2/988	23/18722	0.344419536847063	0.528162984910969	NRP1/SULF2	2
GO:0061050	regulation of cell growth involved in cardiac muscle cell development	2/988	23/18722	0.344419536847063	0.528162984910969	EDN1/IGF1	2
GO:0099590	neurotransmitter receptor internalization	2/988	23/18722	0.344419536847063	0.528162984910969	AP2B1/PPP3R1	2
GO:1902410	mitotic cytokinetic process	2/988	23/18722	0.344419536847063	0.528162984910969	RHOA/PDCD6IP	2
GO:2001169	regulation of ATP biosynthetic process	2/988	23/18722	0.344419536847063	0.528162984910969	TMSB4X/STAT3	2
GO:0006941	striated muscle contraction	11/988	179/18722	0.34576365833125	0.530071155283001	CAV1/PDE4D/CLIC2/SMAD5/CALM1/GJA1/PIK3CA/PDE4B/FLNA/GJA5/GSN	11
GO:0031929	TOR signaling	8/988	126/18722	0.347517708568836	0.532606482376704	AKT3/PIK3CA/HIF1A/CCDC88A/PRKAA1/WAC/SMG1/ZMPSTE24	8
GO:0002275	myeloid cell activation involved in immune response	6/988	91/18722	0.348285174488302	0.533321085869663	FOXF1/PRKCE/DYSF/GATA2/SNAP23/S100A13	6
GO:0045582	positive regulation of T cell differentiation	6/988	91/18722	0.348285174488302	0.533321085869663	HLX/TGFBR2/MDK/RHOA/ZMIZ1/CD46	6
GO:0051983	regulation of chromosome segregation	6/988	91/18722	0.348285174488302	0.533321085869663	RB1/DUSP1/PLSCR1/APC/CDC27/PUM2	6
GO:0010822	positive regulation of mitochondrion organization	5/988	74/18722	0.352020699772562	0.538730612846975	KDR/TNFSF10/DDHD1/HIF1A/RALA	5
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	5/988	74/18722	0.352020699772562	0.538730612846975	FOXP1/PKN1/RHOA/CLOCK/CNOT2	5
GO:0032414	positive regulation of ion transmembrane transporter activity	7/988	109/18722	0.352684592361784	0.539591173567338	TMSB4X/KIF5B/ACTN4/CALM1/STIM2/PKD2/WNK1	7
GO:0032892	positive regulation of organic acid transport	3/988	40/18722	0.354083806275812	0.541264224154565	EDN1/ITGB1/SLC12A2	3
GO:0055081	anion homeostasis	3/988	40/18722	0.354083806275812	0.541264224154565	GLS/SLC12A2/XPR1	3
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	3/988	40/18722	0.354083806275812	0.541264224154565	CLIC2/CALM1/PKD2	3
GO:0006754	ATP biosynthetic process	4/988	57/18722	0.354541834673082	0.541341254896066	TMSB4X/TGFB1/STAT3/ATP6V1A	4
GO:0010883	regulation of lipid storage	4/988	57/18722	0.354541834673082	0.541341254896066	SCARB1/CPT1A/CD36/ABCA1	4
GO:0050891	multicellular organismal water homeostasis	4/988	57/18722	0.354541834673082	0.541341254896066	HYAL2/UGCG/AKAP11/PLEC	4
GO:0060042	retina morphogenesis in camera-type eye	4/988	57/18722	0.354541834673082	0.541341254896066	TSPAN12/HIPK2/PTPRM/HIPK1	4
GO:0006633	fatty acid biosynthetic process	10/988	163/18722	0.358564235040491	0.547325636935371	EDN1/CEACAM1/FABP5/PDK4/LPGAT1/ACSL3/ELOVL5/QKI/HSD17B12/PRKAA1	10
GO:0002292	T cell differentiation involved in immune response	5/988	75/18722	0.36262802226305	0.550828261147914	HLX/FOXP1/STAT3/RC3H1/CD46	5
GO:0006094	gluconeogenesis	5/988	75/18722	0.36262802226305	0.550828261147914	NNMT/LEPR/RANBP2/OGT/ARPP19	5
GO:0033077	T cell differentiation in thymus	5/988	75/18722	0.36262802226305	0.550828261147914	B2M/ZFP36L1/ZFP36L2/SOS2/SOS1	5
GO:0034121	regulation of toll-like receptor signaling pathway	5/988	75/18722	0.36262802226305	0.550828261147914	CAV1/CD36/RTN4/WDFY1/PJA2	5
GO:2001259	positive regulation of cation channel activity	5/988	75/18722	0.36262802226305	0.550828261147914	TMSB4X/KIF5B/CALM1/STIM2/PKD2	5
GO:0033865	nucleoside bisphosphate metabolic process	8/988	128/18722	0.363615350069235	0.550828261147914	PAPSS2/PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A/FAR1	8
GO:0033875	ribonucleoside bisphosphate metabolic process	8/988	128/18722	0.363615350069235	0.550828261147914	PAPSS2/PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A/FAR1	8
GO:0034032	purine nucleoside bisphosphate metabolic process	8/988	128/18722	0.363615350069235	0.550828261147914	PAPSS2/PDK4/ACSL3/ELOVL5/HSD17B12/ACAT1/DIP2A/FAR1	8
GO:0001702	gastrulation with mouth forming second	2/988	24/18722	0.363866033201813	0.550828261147914	ETS2/SMAD4	2
GO:0002438	acute inflammatory response to antigenic stimulus	2/988	24/18722	0.363866033201813	0.550828261147914	FCGR2B/HLA-E	2
GO:0010155	regulation of proton transport	2/988	24/18722	0.363866033201813	0.550828261147914	TMSB4X/ACTN4	2
GO:0016486	peptide hormone processing	2/988	24/18722	0.363866033201813	0.550828261147914	ECE1/PCSK5	2
GO:0018230	peptidyl-L-cysteine S-palmitoylation	2/988	24/18722	0.363866033201813	0.550828261147914	ZDHHC17/GOLGA7	2
GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	2/988	24/18722	0.363866033201813	0.550828261147914	ZDHHC17/GOLGA7	2
GO:0030810	positive regulation of nucleotide biosynthetic process	2/988	24/18722	0.363866033201813	0.550828261147914	TMSB4X/STAT3	2
GO:0030878	thyroid gland development	2/988	24/18722	0.363866033201813	0.550828261147914	THRA/MAPK1	2
GO:0031639	plasminogen activation	2/988	24/18722	0.363866033201813	0.550828261147914	CLEC3B/THBS1	2
GO:0032928	regulation of superoxide anion generation	2/988	24/18722	0.363866033201813	0.550828261147914	GNAI2/TGFB1	2
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	2/988	24/18722	0.363866033201813	0.550828261147914	THBS1/SULF2	2
GO:0043302	positive regulation of leukocyte degranulation	2/988	24/18722	0.363866033201813	0.550828261147914	LAMP1/GATA2	2
GO:0048011	neurotrophin TRK receptor signaling pathway	2/988	24/18722	0.363866033201813	0.550828261147914	ZDHHC17/SOS1	2
GO:0051570	regulation of histone H3-K9 methylation	2/988	24/18722	0.363866033201813	0.550828261147914	ATRX/RIF1	2
GO:0051905	establishment of pigment granule localization	2/988	24/18722	0.363866033201813	0.550828261147914	RAB27A/RAB11A	2
GO:0060561	apoptotic process involved in morphogenesis	2/988	24/18722	0.363866033201813	0.550828261147914	NOTCH1/TNFRSF1B	2
GO:0060571	morphogenesis of an epithelial fold	2/988	24/18722	0.363866033201813	0.550828261147914	LUZP1/HIF1A	2
GO:0070841	inclusion body assembly	2/988	24/18722	0.363866033201813	0.550828261147914	CLU/HSPA1A	2
GO:0098743	cell aggregation	2/988	24/18722	0.363866033201813	0.550828261147914	MGP/THRA	2
GO:1900373	positive regulation of purine nucleotide biosynthetic process	2/988	24/18722	0.363866033201813	0.550828261147914	TMSB4X/STAT3	2
GO:2000353	positive regulation of endothelial cell apoptotic process	2/988	24/18722	0.363866033201813	0.550828261147914	THBS1/RGCC	2
GO:0045580	regulation of T cell differentiation	9/988	146/18722	0.364956753201248	0.552322015101148	HLX/TGFBR2/MDK/RHOA/ZMIZ1/RC3H1/CD46/SOS2/SOS1	9
GO:0030072	peptide hormone secretion	14/988	236/18722	0.365103506342446	0.552386734745392	EDN1/CRHBP/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	14
GO:0050806	positive regulation of synaptic transmission	10/988	164/18722	0.365677977805655	0.552940910362551	LAMA2/PRKCE/KIF5B/APP/STX3/PTEN/CREB1/NPTN/MAPK1/PLK2	10
GO:2001242	regulation of intrinsic apoptotic signaling pathway	10/988	164/18722	0.365677977805655	0.552940910362551	CAV1/SKIL/CLU/SERINC3/HIF1A/TMBIM6/CYLD/CD44/HNRNPK/HSPA1A	10
GO:0002791	regulation of peptide secretion	12/988	200/18722	0.365899723819421	0.553118762927936	CRHBP/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CLOCK/PPP3CA/PIM3/MIDN	12
GO:0007405	neuroblast proliferation	4/988	58/18722	0.366706439680243	0.553707961222698	VEGFC/NOTCH1/HIF1A/CTNNA1	4
GO:0010043	response to zinc ion	4/988	58/18722	0.366706439680243	0.553707961222698	PAM/PTEN/CREB1/SLC30A1	4
GO:0010574	regulation of vascular endothelial growth factor production	4/988	58/18722	0.366706439680243	0.553707961222698	SULF2/IL6ST/TGFB1/HIF1A	4
GO:0097035	regulation of membrane lipid distribution	4/988	58/18722	0.366706439680243	0.553707961222698	PLSCR4/ATP11A/ABCA1/PLSCR1	4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	6/988	93/18722	0.367314133762422	0.554310420041473	TMSB4X/CD200/TAX1BP1/CARD8/KLF4/CYLD	6
GO:0060993	kidney morphogenesis	6/988	93/18722	0.367314133762422	0.554310420041473	DCHS1/WWTR1/PKD2/HES1/SMAD4/ZMPSTE24	6
GO:0032735	positive regulation of interleukin-12 production	3/988	41/18722	0.368707786856309	0.555309261066263	PLCB1/MDK/CD36	3
GO:0044786	cell cycle DNA replication	3/988	41/18722	0.368707786856309	0.555309261066263	DACH1/ATRX/ZMPSTE24	3
GO:1900371	regulation of purine nucleotide biosynthetic process	3/988	41/18722	0.368707786856309	0.555309261066263	TMSB4X/PDK4/STAT3	3
GO:1901385	regulation of voltage-gated calcium channel activity	3/988	41/18722	0.368707786856309	0.555309261066263	CALM1/PDE4B/AHNAK	3
GO:1902116	negative regulation of organelle assembly	3/988	41/18722	0.368707786856309	0.555309261066263	FEZ2/MAP4/SMAD4	3
GO:1903524	positive regulation of blood circulation	3/988	41/18722	0.368707786856309	0.555309261066263	EDN1/PDE4D/ADRB1	3
GO:2000008	regulation of protein localization to cell surface	3/988	41/18722	0.368707786856309	0.555309261066263	STX3/PICALM/LEPROT	3
GO:1902652	secondary alcohol metabolic process	9/988	147/18722	0.372516681653415	0.560886795051854	LEPR/SCARF1/SCARB1/APP/ABCA1/LBR/PRKAA1/CYB5R3/NFE2L1	9
GO:0008652	cellular amino acid biosynthetic process	5/988	76/18722	0.373242259069936	0.561501806904418	SERINC3/GLS/MRI1/PLOD2/ATP2B4	5
GO:0086001	cardiac muscle cell action potential	5/988	76/18722	0.373242259069936	0.561501806904418	CAV1/CALM1/GJA1/FLNA/GJA5	5
GO:0140029	exocytic process	5/988	76/18722	0.373242259069936	0.561501806904418	EXOC6/STX3/RALB/SNAP23/CTBP2	5
GO:0010389	regulation of G2/M transition of mitotic cell cycle	6/988	94/18722	0.376847408419941	0.566444095508412	APP/TAOK1/CDC25B/CCND1/RAB11A/FOXN3	6
GO:0030316	osteoclast differentiation	6/988	94/18722	0.376847408419941	0.566444095508412	CD109/FOXP1/CD81/GLO1/CREB1/KLF10	6
GO:0051702	biological process involved in interaction with symbiont	6/988	94/18722	0.376847408419941	0.566444095508412	IFI27/FN1/CAV2/STOM/JUN/CCNT1	6
GO:0016051	carbohydrate biosynthetic process	12/988	202/18722	0.37881260927313	0.568340865429684	IGF1/NNMT/LEPR/P2RY1/IGF2/PDGFB/TGFB1/RANBP2/OGT/ARPP19/GBE1/B4GALT5	12
GO:0090087	regulation of peptide transport	12/988	202/18722	0.37881260927313	0.568340865429684	CRHBP/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/CLOCK/PPP3CA/PIM3/MIDN	12
GO:0046632	alpha-beta T cell differentiation	7/988	112/18722	0.378815678227415	0.568340865429684	HLX/FOXP1/TGFBR2/RHOA/STAT3/RC3H1/ATF2	7
GO:0001836	release of cytochrome c from mitochondria	4/988	59/18722	0.378858246326527	0.568340865429684	IGF1/TNFSF10/CLU/JUN	4
GO:0006767	water-soluble vitamin metabolic process	4/988	59/18722	0.378858246326527	0.568340865429684	NNMT/SLC2A1/CD320/SLC2A3	4
GO:0048278	vesicle docking	4/988	59/18722	0.378858246326527	0.568340865429684	CAV2/STX3/RALB/CTBP2	4
GO:0071806	protein transmembrane transport	4/988	59/18722	0.378858246326527	0.568340865429684	TRAM1/SEC62/ABCA1/SEC61A1	4
GO:0006282	regulation of DNA repair	8/988	130/18722	0.379780627083999	0.569242294320035	PML/SLF2/ACTR2/PARP9/DTX3L/TRIP12/KMT5B/RIF1	8
GO:0006352	DNA-templated transcription, initiation	8/988	130/18722	0.379780627083999	0.569242294320035	THRA/SETX/CREB1/RSF1/MED13/ATF7IP/BAZ2A/JUN	8
GO:0015918	sterol transport	8/988	130/18722	0.379780627083999	0.569242294320035	LRP6/CAV1/SCARB1/CLU/OSBPL10/CD36/ABCA1/STARD4	8
GO:0016540	protein autoprocessing	2/988	25/18722	0.383087973335954	0.570449991965873	CAPN2/FAM111A	2
GO:0021846	cell proliferation in forebrain	2/988	25/18722	0.383087973335954	0.570449991965873	DIXDC1/PCM1	2
GO:0030318	melanocyte differentiation	2/988	25/18722	0.383087973335954	0.570449991965873	MEF2C/RAB27A	2
GO:0032331	negative regulation of chondrocyte differentiation	2/988	25/18722	0.383087973335954	0.570449991965873	EFEMP1/LTBP3	2
GO:0032400	melanosome localization	2/988	25/18722	0.383087973335954	0.570449991965873	RAB27A/RAB11A	2
GO:0036315	cellular response to sterol	2/988	25/18722	0.383087973335954	0.570449991965873	LRP6/ABCA1	2
GO:0042832	defense response to protozoan	2/988	25/18722	0.383087973335954	0.570449991965873	GBP4/LYST	2
GO:0045109	intermediate filament organization	2/988	25/18722	0.383087973335954	0.570449991965873	VIM/PLEC	2
GO:0046039	GTP metabolic process	2/988	25/18722	0.383087973335954	0.570449991965873	GIMAP7/RHOA	2
GO:0051788	response to misfolded protein	2/988	25/18722	0.383087973335954	0.570449991965873	CLU/ATXN3	2
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	2/988	25/18722	0.383087973335954	0.570449991965873	CREB1/MED13	2
GO:0061436	establishment of skin barrier	2/988	25/18722	0.383087973335954	0.570449991965873	UGCG/PLEC	2
GO:0062149	detection of stimulus involved in sensory perception of pain	2/988	25/18722	0.383087973335954	0.570449991965873	ITGA2/FYN	2
GO:0140448	signaling receptor ligand precursor processing	2/988	25/18722	0.383087973335954	0.570449991965873	ECE1/PCSK5	2
GO:1901623	regulation of lymphocyte chemotaxis	2/988	25/18722	0.383087973335954	0.570449991965873	ADAM10/WNK1	2
GO:1902932	positive regulation of alcohol biosynthetic process	2/988	25/18722	0.383087973335954	0.570449991965873	P2RY1/PRKAA1	2
GO:1904753	negative regulation of vascular associated smooth muscle cell migration	2/988	25/18722	0.383087973335954	0.570449991965873	MEF2C/RHOA	2
GO:0000266	mitochondrial fission	3/988	42/18722	0.383271088352071	0.570449991965873	KDR/DDHD1/RALA	3
GO:0014912	negative regulation of smooth muscle cell migration	3/988	42/18722	0.383271088352071	0.570449991965873	MEF2C/IGFBP3/RHOA	3
GO:0030808	regulation of nucleotide biosynthetic process	3/988	42/18722	0.383271088352071	0.570449991965873	TMSB4X/PDK4/STAT3	3
GO:0030890	positive regulation of B cell proliferation	3/988	42/18722	0.383271088352071	0.570449991965873	MEF2C/CD81/CD320	3
GO:0033003	regulation of mast cell activation	3/988	42/18722	0.383271088352071	0.570449991965873	FOXF1/GATA2/PLSCR1	3
GO:0046688	response to copper ion	3/988	42/18722	0.383271088352071	0.570449991965873	LOXL2/PAM/APP	3
GO:0048489	synaptic vesicle transport	3/988	42/18722	0.383271088352071	0.570449991965873	KIF5B/RAB27A/PICALM	3
GO:1900274	regulation of phospholipase C activity	3/988	42/18722	0.383271088352071	0.570449991965873	BICD1/FGFR1/GNAQ	3
GO:0021675	nerve development	5/988	77/18722	0.383855515501702	0.570999859519754	NRP1/SULF2/DICER1/SEMA3F/HES1	5
GO:0140056	organelle localization by membrane tethering	5/988	77/18722	0.383855515501702	0.570999859519754	CAV2/CALM1/STX3/RALB/CTBP2	5
GO:0006942	regulation of striated muscle contraction	6/988	95/18722	0.386385467276018	0.574602352231301	CAV1/PDE4D/CLIC2/CALM1/PDE4B/GJA5	6
GO:0055088	lipid homeostasis	10/988	167/18722	0.387107610377514	0.575515148705668	FABP4/MALL/ZBTB20/CAV1/SCARB1/ABCA1/RTN4/PRKAA1/NR1D2/CNBP	10
GO:0044106	cellular amine metabolic process	7/988	113/18722	0.387547828281652	0.57600841181649	NNMT/IDO1/NPR1/EPAS1/SLC44A1/ATP2B4/OAZ2	7
GO:0009411	response to UV	9/988	149/18722	0.387674762216117	0.576035898431332	HYAL2/TIMP1/CARD16/PML/TP53INP1/POLK/CCND1/PRKAA1/NEDD4	9
GO:0030071	regulation of mitotic metaphase/anaphase transition	4/988	60/18722	0.390986019759331	0.580793550604464	RB1/DUSP1/APC/CDC27	4
GO:0000070	mitotic sister chromatid segregation	10/988	168/18722	0.394272020875166	0.585136022810552	RB1/DUSP1/ATRX/PDS5B/SLF2/POGZ/APC/CDC27/NIPBL/RAB11A	10
GO:0002833	positive regulation of response to biotic stimulus	10/988	168/18722	0.394272020875166	0.585136022810552	HLA-E/IFI16/SASH1/DDX60/FYN/LAMP1/PARP9/PLSCR1/PAK2/PUM2	10
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	5/988	78/18722	0.394460108750864	0.585136022810552	EDN1/S1PR1/P2RY1/GNAI2/FLNA	5
GO:0019319	hexose biosynthetic process	5/988	78/18722	0.394460108750864	0.585136022810552	NNMT/LEPR/RANBP2/OGT/ARPP19	5
GO:0032024	positive regulation of insulin secretion	5/988	78/18722	0.394460108750864	0.585136022810552	NNAT/PRKCE/KIF5B/GJA1/HIF1A	5
GO:0034620	cellular response to unfolded protein	6/988	96/18722	0.395922644258636	0.586977696428097	ERO1A/TMBIM6/EIF2AK2/CCND1/ATF6/HSPA1A	6
GO:0042632	cholesterol homeostasis	6/988	96/18722	0.395922644258636	0.586977696428097	FABP4/MALL/CAV1/SCARB1/ABCA1/CNBP	6
GO:0030517	negative regulation of axon extension	3/988	43/18722	0.397756232943394	0.589202763356193	NRP1/SEMA3F/RTN4	3
GO:1903793	positive regulation of anion transport	3/988	43/18722	0.397756232943394	0.589202763356193	EDN1/ITGB1/SLC12A2	3
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	3/988	43/18722	0.397756232943394	0.589202763356193	MEF2C/PTEN/RHOA	3
GO:0001556	oocyte maturation	2/988	26/18722	0.402054907743647	0.59079271644101	RPS6KA2/CDC25B	2
GO:0001562	response to protozoan	2/988	26/18722	0.402054907743647	0.59079271644101	GBP4/LYST	2
GO:0001573	ganglioside metabolic process	2/988	26/18722	0.402054907743647	0.59079271644101	ST3GAL5/B4GALT5	2
GO:0003416	endochondral bone growth	2/988	26/18722	0.402054907743647	0.59079271644101	TGFBR2/ZMPSTE24	2
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2/988	26/18722	0.402054907743647	0.59079271644101	TRAM1/SEC61A1	2
GO:0006706	steroid catabolic process	2/988	26/18722	0.402054907743647	0.59079271644101	SCARF1/SCARB1	2
GO:0007214	gamma-aminobutyric acid signaling pathway	2/988	26/18722	0.402054907743647	0.59079271644101	GNAI2/SLC12A2	2
GO:0010875	positive regulation of cholesterol efflux	2/988	26/18722	0.402054907743647	0.59079271644101	CAV1/ABCA1	2
GO:0021952	central nervous system projection neuron axonogenesis	2/988	26/18722	0.402054907743647	0.59079271644101	NFIB/NIN	2
GO:0034643	establishment of mitochondrion localization, microtubule-mediated	2/988	26/18722	0.402054907743647	0.59079271644101	ARMCX3/HIF1A	2
GO:0043501	skeletal muscle adaptation	2/988	26/18722	0.402054907743647	0.59079271644101	CFLAR/PPP3CA	2
GO:0045026	plasma membrane fusion	2/988	26/18722	0.402054907743647	0.59079271644101	TIE1/CD9	2
GO:0045672	positive regulation of osteoclast differentiation	2/988	26/18722	0.402054907743647	0.59079271644101	CREB1/KLF10	2
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	2/988	26/18722	0.402054907743647	0.59079271644101	HLA-E/LAMP1	2
GO:0046639	negative regulation of alpha-beta T cell differentiation	2/988	26/18722	0.402054907743647	0.59079271644101	HLX/RC3H1	2
GO:0046755	viral budding	2/988	26/18722	0.402054907743647	0.59079271644101	PDCD6IP/NEDD4	2
GO:0047497	mitochondrion transport along microtubule	2/988	26/18722	0.402054907743647	0.59079271644101	ARMCX3/HIF1A	2
GO:0048499	synaptic vesicle membrane organization	2/988	26/18722	0.402054907743647	0.59079271644101	STX3/SNAP23	2
GO:0048668	collateral sprouting	2/988	26/18722	0.402054907743647	0.59079271644101	APP/NIN	2
GO:0048843	negative regulation of axon extension involved in axon guidance	2/988	26/18722	0.402054907743647	0.59079271644101	NRP1/SEMA3F	2
GO:0051875	pigment granule localization	2/988	26/18722	0.402054907743647	0.59079271644101	RAB27A/RAB11A	2
GO:0072273	metanephric nephron morphogenesis	2/988	26/18722	0.402054907743647	0.59079271644101	PKD2/HES1	2
GO:0097066	response to thyroid hormone	2/988	26/18722	0.402054907743647	0.59079271644101	LMO2/RDX	2
GO:0097186	amelogenesis	2/988	26/18722	0.402054907743647	0.59079271644101	FOXO1/ATF2	2
GO:1900017	positive regulation of cytokine production involved in inflammatory response	2/988	26/18722	0.402054907743647	0.59079271644101	HIF1A/STAT3	2
GO:1904353	regulation of telomere capping	2/988	26/18722	0.402054907743647	0.59079271644101	NEK7/MAPK1	2
GO:1904861	excitatory synapse assembly	2/988	26/18722	0.402054907743647	0.59079271644101	PTEN/NPTN	2
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	2/988	26/18722	0.402054907743647	0.59079271644101	ENG/PDGFB	2
GO:2000050	regulation of non-canonical Wnt signaling pathway	2/988	26/18722	0.402054907743647	0.59079271644101	RSPO3/RNF213	2
GO:0006900	vesicle budding from membrane	4/988	61/18722	0.403078974130166	0.591970005689645	PICALM/SEC23A/SEC31A/WASL	4
GO:1904356	regulation of telomere maintenance via telomere lengthening	4/988	61/18722	0.403078974130166	0.591970005689645	HMBOX1/NEK7/MAPK1/XRN1	4
GO:0006023	aminoglycan biosynthetic process	5/988	79/18722	0.405048575924657	0.594533858886924	ANGPT1/PDGFB/CHSY1/TGFB1/B4GALT5	5
GO:0006029	proteoglycan metabolic process	5/988	79/18722	0.405048575924657	0.594533858886924	IGF1/NDNF/BMPR2/SULF2/CHSY1	5
GO:0055092	sterol homeostasis	6/988	97/18722	0.405453395474534	0.594963656563737	FABP4/MALL/CAV1/SCARB1/ABCA1/CNBP	6
GO:0006575	cellular modified amino acid metabolic process	11/988	188/18722	0.406709521365652	0.596469721076941	PLA1A/CLIC2/MGST2/SERINC3/SERINC1/OSBPL10/CPT1A/PLOD2/GLO1/PLSCR1/SLC16A2	11
GO:0008037	cell recognition	13/988	225/18722	0.409043289654132	0.596469721076941	PECAM1/ROBO4/PCDH12/SCARB1/MSN/CD81/NRP1/APP/PALLD/CD36/NPTN/RTN4/CD9	13
GO:0005978	glycogen biosynthetic process	3/988	44/18722	0.412146863847736	0.596469721076941	IGF1/IGF2/GBE1	3
GO:0006378	mRNA polyadenylation	3/988	44/18722	0.412146863847736	0.596469721076941	APP/PABPC1/CCNT1	3
GO:0009250	glucan biosynthetic process	3/988	44/18722	0.412146863847736	0.596469721076941	IGF1/IGF2/GBE1	3
GO:0042554	superoxide anion generation	3/988	44/18722	0.412146863847736	0.596469721076941	EDN1/GNAI2/TGFB1	3
GO:0045124	regulation of bone resorption	3/988	44/18722	0.412146863847736	0.596469721076941	S1PR1/PDK4/LTBP3	3
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	3/988	44/18722	0.412146863847736	0.596469721076941	F2R/NOTCH1/HES1	3
GO:0048806	genitalia development	3/988	44/18722	0.412146863847736	0.596469721076941	HOXA13/TBX3/NIPBL	3
GO:0051150	regulation of smooth muscle cell differentiation	3/988	44/18722	0.412146863847736	0.596469721076941	ENG/PDGFB/PIAS1	3
GO:1903573	negative regulation of response to endoplasmic reticulum stress	3/988	44/18722	0.412146863847736	0.596469721076941	CLU/TMBIM6/HSPA1A	3
GO:0098813	nuclear chromosome segregation	16/988	281/18722	0.413710008999275	0.596469721076941	RB1/TTL/DUSP1/ATRX/PDS5B/SLF2/POGZ/ACTR2/SUN1/APC/STAG2/CDC27/NIPBL/RAB11A/DYNC1H1/CDC42	16
GO:0035967	cellular response to topologically incorrect protein	7/988	116/18722	0.413748147811677	0.596469721076941	ATXN3/ERO1A/TMBIM6/EIF2AK2/CCND1/ATF6/HSPA1A	7
GO:0043200	response to amino acid	7/988	116/18722	0.413748147811677	0.596469721076941	EDN1/COL4A1/FYN/CAPN2/RHOA/TMBIM6/CREB1	7
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	4/988	62/18722	0.415126778438256	0.596469721076941	RB1/DUSP1/APC/CDC27	4
GO:0010573	vascular endothelial growth factor production	4/988	62/18722	0.415126778438256	0.596469721076941	SULF2/IL6ST/TGFB1/HIF1A	4
GO:0031124	mRNA 3'-end processing	4/988	62/18722	0.415126778438256	0.596469721076941	ZFP36L1/APP/PABPC1/CCNT1	4
GO:0060675	ureteric bud morphogenesis	4/988	62/18722	0.415126778438256	0.596469721076941	DCHS1/PKD2/HES1/SMAD4	4
GO:0006486	protein glycosylation	13/988	226/18722	0.415279002746586	0.596469721076941	EOGT/ST6GAL1/ST3GAL5/FUT11/MGAT4A/OGT/EDEM3/MAN1A1/MAGT1/DPY19L4/B4GALT5/RPN1/TMTC3	13
GO:0043413	macromolecule glycosylation	13/988	226/18722	0.415279002746586	0.596469721076941	EOGT/ST6GAL1/ST3GAL5/FUT11/MGAT4A/OGT/EDEM3/MAN1A1/MAGT1/DPY19L4/B4GALT5/RPN1/TMTC3	13
GO:0051303	establishment of chromosome localization	5/988	80/18722	0.415613681034955	0.596469721076941	TTL/ACTR2/SUN1/RAB11A/DYNC1H1	5
GO:0001553	luteinization	1/988	10/18722	0.418584700181776	0.596469721076941	FZD4	1
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	1/988	10/18722	0.418584700181776	0.596469721076941	CD81	1
GO:0003163	sinoatrial node development	1/988	10/18722	0.418584700181776	0.596469721076941	TBX3	1
GO:0006171	cAMP biosynthetic process	1/988	10/18722	0.418584700181776	0.596469721076941	ADCY4	1
GO:0006646	phosphatidylethanolamine biosynthetic process	1/988	10/18722	0.418584700181776	0.596469721076941	ETNK1	1
GO:0007168	receptor guanylyl cyclase signaling pathway	1/988	10/18722	0.418584700181776	0.596469721076941	NPR1	1
GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	1/988	10/18722	0.418584700181776	0.596469721076941	GNB1	1
GO:0009169	purine ribonucleoside monophosphate catabolic process	1/988	10/18722	0.418584700181776	0.596469721076941	NT5E	1
GO:0010172	embryonic body morphogenesis	1/988	10/18722	0.418584700181776	0.596469721076941	PHLDB2	1
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	1/988	10/18722	0.418584700181776	0.596469721076941	EIF2AK2	1
GO:0015696	ammonium transport	1/988	10/18722	0.418584700181776	0.596469721076941	SLC12A2	1
GO:0016081	synaptic vesicle docking	1/988	10/18722	0.418584700181776	0.596469721076941	CTBP2	1
GO:0019062	virion attachment to host cell	1/988	10/18722	0.418584700181776	0.596469721076941	CD81	1
GO:0021548	pons development	1/988	10/18722	0.418584700181776	0.596469721076941	ATF2	1
GO:0021562	vestibulocochlear nerve development	1/988	10/18722	0.418584700181776	0.596469721076941	NRP1	1
GO:0021903	rostrocaudal neural tube patterning	1/988	10/18722	0.418584700181776	0.596469721076941	HES1	1
GO:0030953	astral microtubule organization	1/988	10/18722	0.418584700181776	0.596469721076941	RAB11A	1
GO:0031340	positive regulation of vesicle fusion	1/988	10/18722	0.418584700181776	0.596469721076941	KIF5B	1
GO:0032253	dense core granule localization	1/988	10/18722	0.418584700181776	0.596469721076941	KIF5B	1
GO:0032525	somite rostral/caudal axis specification	1/988	10/18722	0.418584700181776	0.596469721076941	SMAD4	1
GO:0034756	regulation of iron ion transport	1/988	10/18722	0.418584700181776	0.596469721076941	B2M	1
GO:0035520	monoubiquitinated protein deubiquitination	1/988	10/18722	0.418584700181776	0.596469721076941	ATXN3	1
GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	1/988	10/18722	0.418584700181776	0.596469721076941	FGFR1	1
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	1/988	10/18722	0.418584700181776	0.596469721076941	SULF2	1
GO:0036109	alpha-linolenic acid metabolic process	1/988	10/18722	0.418584700181776	0.596469721076941	ELOVL5	1
GO:0038007	netrin-activated signaling pathway	1/988	10/18722	0.418584700181776	0.596469721076941	PTK2	1
GO:0042711	maternal behavior	1/988	10/18722	0.418584700181776	0.596469721076941	PTEN	1
GO:0042996	regulation of Golgi to plasma membrane protein transport	1/988	10/18722	0.418584700181776	0.596469721076941	ACSL3	1
GO:0043084	penile erection	1/988	10/18722	0.418584700181776	0.596469721076941	P2RY1	1
GO:0045625	regulation of T-helper 1 cell differentiation	1/988	10/18722	0.418584700181776	0.596469721076941	HLX	1
GO:0045843	negative regulation of striated muscle tissue development	1/988	10/18722	0.418584700181776	0.596469721076941	TGFB1	1
GO:0048251	elastic fiber assembly	1/988	10/18722	0.418584700181776	0.596469721076941	LTBP3	1
GO:0048262	determination of dorsal/ventral asymmetry	1/988	10/18722	0.418584700181776	0.596469721076941	AIDA	1
GO:0048280	vesicle fusion with Golgi apparatus	1/988	10/18722	0.418584700181776	0.596469721076941	YIPF4	1
GO:0048340	paraxial mesoderm morphogenesis	1/988	10/18722	0.418584700181776	0.596469721076941	SMAD2	1
GO:0048703	embryonic viscerocranium morphogenesis	1/988	10/18722	0.418584700181776	0.596469721076941	NIPBL	1
GO:0048755	branching morphogenesis of a nerve	1/988	10/18722	0.418584700181776	0.596469721076941	RTN4	1
GO:0051351	positive regulation of ligase activity	1/988	10/18722	0.418584700181776	0.596469721076941	TMSB4X	1
GO:0051409	response to nitrosative stress	1/988	10/18722	0.418584700181776	0.596469721076941	DUSP6	1
GO:0060525	prostate glandular acinus development	1/988	10/18722	0.418584700181776	0.596469721076941	NOTCH1	1
GO:0060736	prostate gland growth	1/988	10/18722	0.418584700181776	0.596469721076941	PTEN	1
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	1/988	10/18722	0.418584700181776	0.596469721076941	NOTCH1	1
GO:0060923	cardiac muscle cell fate commitment	1/988	10/18722	0.418584700181776	0.596469721076941	TBX3	1
GO:0060947	cardiac vascular smooth muscle cell differentiation	1/988	10/18722	0.418584700181776	0.596469721076941	NOTCH1	1
GO:0061085	regulation of histone H3-K27 methylation	1/988	10/18722	0.418584700181776	0.596469721076941	OGT	1
GO:0061140	lung secretory cell differentiation	1/988	10/18722	0.418584700181776	0.596469721076941	NFIB	1
GO:0070391	response to lipoteichoic acid	1/988	10/18722	0.418584700181776	0.596469721076941	CD36	1
GO:0070544	histone H3-K36 demethylation	1/988	10/18722	0.418584700181776	0.596469721076941	KDM7A	1
GO:0071223	cellular response to lipoteichoic acid	1/988	10/18722	0.418584700181776	0.596469721076941	CD36	1
GO:0071372	cellular response to follicle-stimulating hormone stimulus	1/988	10/18722	0.418584700181776	0.596469721076941	NOTCH1	1
GO:0071838	cell proliferation in bone marrow	1/988	10/18722	0.418584700181776	0.596469721076941	MAP3K3	1
GO:0072203	cell proliferation involved in metanephros development	1/988	10/18722	0.418584700181776	0.596469721076941	EGR1	1
GO:0072378	blood coagulation, fibrin clot formation	1/988	10/18722	0.418584700181776	0.596469721076941	FN1	1
GO:0072488	ammonium transmembrane transport	1/988	10/18722	0.418584700181776	0.596469721076941	SLC12A2	1
GO:0097105	presynaptic membrane assembly	1/988	10/18722	0.418584700181776	0.596469721076941	PTEN	1
GO:0097250	mitochondrial respirasome assembly	1/988	10/18722	0.418584700181776	0.596469721076941	COX7A1	1
GO:0098885	modification of postsynaptic actin cytoskeleton	1/988	10/18722	0.418584700181776	0.596469721076941	RHOA	1
GO:0099171	presynaptic modulation of chemical synaptic transmission	1/988	10/18722	0.418584700181776	0.596469721076941	GIT1	1
GO:0099519	dense core granule cytoskeletal transport	1/988	10/18722	0.418584700181776	0.596469721076941	KIF5B	1
GO:0099532	synaptic vesicle endosomal processing	1/988	10/18722	0.418584700181776	0.596469721076941	ITSN2	1
GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	1/988	10/18722	0.418584700181776	0.596469721076941	RAB11A	1
GO:0140059	dendrite arborization	1/988	10/18722	0.418584700181776	0.596469721076941	NRP1	1
GO:1901524	regulation of mitophagy	1/988	10/18722	0.418584700181776	0.596469721076941	VPS13C	1
GO:1901950	dense core granule transport	1/988	10/18722	0.418584700181776	0.596469721076941	KIF5B	1
GO:1901993	regulation of meiotic cell cycle phase transition	1/988	10/18722	0.418584700181776	0.596469721076941	CDC25B	1
GO:1902224	ketone body metabolic process	1/988	10/18722	0.418584700181776	0.596469721076941	ACAT1	1
GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	1/988	10/18722	0.418584700181776	0.596469721076941	SERINC3	1
GO:1902513	regulation of organelle transport along microtubule	1/988	10/18722	0.418584700181776	0.596469721076941	LAMP1	1
GO:1902855	regulation of non-motile cilium assembly	1/988	10/18722	0.418584700181776	0.596469721076941	MAP4	1
GO:1903867	extraembryonic membrane development	1/988	10/18722	0.418584700181776	0.596469721076941	HTRA1	1
GO:1904350	regulation of protein catabolic process in the vacuole	1/988	10/18722	0.418584700181776	0.596469721076941	CD81	1
GO:1904526	regulation of microtubule binding	1/988	10/18722	0.418584700181776	0.596469721076941	PPP2CB	1
GO:1904668	positive regulation of ubiquitin protein ligase activity	1/988	10/18722	0.418584700181776	0.596469721076941	PTEN	1
GO:1905383	protein localization to presynapse	1/988	10/18722	0.418584700181776	0.596469721076941	KIF5B	1
GO:1905809	negative regulation of synapse organization	1/988	10/18722	0.418584700181776	0.596469721076941	ARHGEF15	1
GO:1990535	neuron projection maintenance	1/988	10/18722	0.418584700181776	0.596469721076941	APP	1
GO:1990700	nucleolar chromatin organization	1/988	10/18722	0.418584700181776	0.596469721076941	BAZ2A	1
GO:2000121	regulation of removal of superoxide radicals	1/988	10/18722	0.418584700181776	0.596469721076941	CD36	1
GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	1/988	10/18722	0.418584700181776	0.596469721076941	FGFR1	1
GO:2000659	regulation of interleukin-1-mediated signaling pathway	1/988	10/18722	0.418584700181776	0.596469721076941	IL1R1	1
GO:2000726	negative regulation of cardiac muscle cell differentiation	1/988	10/18722	0.418584700181776	0.596469721076941	SMAD4	1
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	1/988	10/18722	0.418584700181776	0.596469721076941	CTNNA1	1
GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1/988	10/18722	0.418584700181776	0.596469721076941	GSN	1
GO:0001958	endochondral ossification	2/988	27/18722	0.420740219291283	0.596469721076941	TEK/MEF2C	2
GO:0002825	regulation of T-helper 1 type immune response	2/988	27/18722	0.420740219291283	0.596469721076941	HLX/IL1R1	2
GO:0007628	adult walking behavior	2/988	27/18722	0.420740219291283	0.596469721076941	HIPK2/ZMPSTE24	2
GO:0010561	negative regulation of glycoprotein biosynthetic process	2/988	27/18722	0.420740219291283	0.596469721076941	ITM2A/ITM2B	2
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	2/988	27/18722	0.420740219291283	0.596469721076941	CLIC2/CALM1	2
GO:0014850	response to muscle activity	2/988	27/18722	0.420740219291283	0.596469721076941	ITGA2/HIF1A	2
GO:0018904	ether metabolic process	2/988	27/18722	0.420740219291283	0.596469721076941	AGPS/FAR1	2
GO:0033561	regulation of water loss via skin	2/988	27/18722	0.420740219291283	0.596469721076941	UGCG/PLEC	2
GO:0033688	regulation of osteoblast proliferation	2/988	27/18722	0.420740219291283	0.596469721076941	RHOA/EIF2AK2	2
GO:0034377	plasma lipoprotein particle assembly	2/988	27/18722	0.420740219291283	0.596469721076941	ACSL3/ABCA1	2
GO:0034505	tooth mineralization	2/988	27/18722	0.420740219291283	0.596469721076941	FOXO1/BCOR	2
GO:0035116	embryonic hindlimb morphogenesis	2/988	27/18722	0.420740219291283	0.596469721076941	NOTCH1/TBX3	2
GO:0036037	CD8-positive, alpha-beta T cell activation	2/988	27/18722	0.420740219291283	0.596469721076941	HLA-E/HLA-A	2
GO:0036075	replacement ossification	2/988	27/18722	0.420740219291283	0.596469721076941	TEK/MEF2C	2
GO:0042104	positive regulation of activated T cell proliferation	2/988	27/18722	0.420740219291283	0.596469721076941	IGF1/IGF2	2
GO:0042402	cellular biogenic amine catabolic process	2/988	27/18722	0.420740219291283	0.596469721076941	IDO1/SLC44A1	2
GO:0045606	positive regulation of epidermal cell differentiation	2/988	27/18722	0.420740219291283	0.596469721076941	NOTCH1/PRKCH	2
GO:0046174	polyol catabolic process	2/988	27/18722	0.420740219291283	0.596469721076941	NUDT3/PTEN	2
GO:0048520	positive regulation of behavior	2/988	27/18722	0.420740219291283	0.596469721076941	MEF2C/GJA1	2
GO:0051953	negative regulation of amine transport	2/988	27/18722	0.420740219291283	0.596469721076941	P2RY1/SYT11	2
GO:0099625	ventricular cardiac muscle cell membrane repolarization	2/988	27/18722	0.420740219291283	0.596469721076941	GJA5/ZMPSTE24	2
GO:1903203	regulation of oxidative stress-induced neuron death	2/988	27/18722	0.420740219291283	0.596469721076941	NCOA7/HIF1A	2
GO:1903859	regulation of dendrite extension	2/988	27/18722	0.420740219291283	0.596469721076941	ITSN2/SPAG9	2
GO:0045137	development of primary sexual characteristics	13/988	227/18722	0.421517239651304	0.597411840188828	DACH1/FZD4/TNFSF10/ADAM15/ATRX/FLNA/RNF38/FNDC3A/CSDE1/NR2F2/CTNNA1/CCND1/SMAD4	13
GO:0030301	cholesterol transport	7/988	117/18722	0.422468737007106	0.598600675108494	LRP6/CAV1/SCARB1/CLU/CD36/ABCA1/STARD4	7
GO:0000045	autophagosome assembly	6/988	99/18722	0.424474089326706	0.601196137468668	FEZ2/TP53INP1/RALB/RB1CC1/SH3GLB1/RAB5A	6
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	18/988	320/18722	0.424640042880731	0.601196137468668	NOVA2/DDX17/PABPC1/MBNL1/SETX/QKI/CELF1/SON/MBNL2/SF3B1/LUC7L3/RBM5/DYRK1A/SCAF11/HNRNPH1/HNRNPK/TIA1/PSIP1	18
GO:0000398	mRNA splicing, via spliceosome	18/988	320/18722	0.424640042880731	0.601196137468668	NOVA2/DDX17/PABPC1/MBNL1/SETX/QKI/CELF1/SON/MBNL2/SF3B1/LUC7L3/RBM5/DYRK1A/SCAF11/HNRNPH1/HNRNPK/TIA1/PSIP1	18
GO:2001021	negative regulation of response to DNA damage stimulus	5/988	81/18722	0.426148420990729	0.602923626035725	CLU/CD44/TRIP12/DYRK1A/RIF1	5
GO:0035987	endodermal cell differentiation	3/988	45/18722	0.426427722706367	0.602923626035725	FN1/ITGA5/COL4A2	3
GO:0043631	RNA polyadenylation	3/988	45/18722	0.426427722706367	0.602923626035725	APP/PABPC1/CCNT1	3
GO:0048538	thymus development	3/988	45/18722	0.426427722706367	0.602923626035725	HES1/MAPK1/ZMPSTE24	3
GO:0048599	oocyte development	3/988	45/18722	0.426427722706367	0.602923626035725	IGF1/RPS6KA2/CDC25B	3
GO:0072171	mesonephric tubule morphogenesis	4/988	63/18722	0.427119560347249	0.603419974618242	DCHS1/PKD2/HES1/SMAD4	4
GO:0099601	regulation of neurotransmitter receptor activity	4/988	63/18722	0.427119560347249	0.603419974618242	CRHBP/MEF2C/APP/DLGAP4	4
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	4/988	63/18722	0.427119560347249	0.603419974618242	RB1/DUSP1/APC/CDC27	4
GO:0045727	positive regulation of translation	8/988	136/18722	0.428398168913006	0.605065427616561	VIM/ITGA2/THBS1/PABPC1/RHOA/EIF4G2/MAPK1/CNBP	8
GO:0009308	amine metabolic process	7/988	118/18722	0.431176037275457	0.608514692998996	NNMT/IDO1/NPR1/EPAS1/SLC44A1/ATP2B4/OAZ2	7
GO:0015849	organic acid transport	17/988	303/18722	0.432935095681435	0.608514692998996	EDN1/FABP4/CEACAM1/LRRC8C/FABP5/THBS1/SLC38A2/ITGB1/SERINC3/SLC12A2/CPT1A/GJA1/ACSL3/CD36/SLC2A1/PRKAA1/SLC16A2	17
GO:0046434	organophosphate catabolic process	9/988	155/18722	0.43324646760427	0.608514692998996	NT5E/ENPP2/SCARB1/PDE4D/ENTPD1/NUDT3/PTEN/PDE4B/ACAT1	9
GO:0050714	positive regulation of protein secretion	8/988	137/18722	0.436482935418926	0.608514692998996	IGF1/VEGFC/NNAT/PRKCE/KIF5B/TGFB1/GJA1/HIF1A	8
GO:0046364	monosaccharide biosynthetic process	5/988	82/18722	0.436646030637154	0.608514692998996	NNMT/LEPR/RANBP2/OGT/ARPP19	5
GO:0050000	chromosome localization	5/988	82/18722	0.436646030637154	0.608514692998996	TTL/ACTR2/SUN1/RAB11A/DYNC1H1	5
GO:0017156	calcium-ion regulated exocytosis	4/988	64/18722	0.43904790812867	0.608514692998996	SYT11/NOTCH1/GNAI2/MYH9	4
GO:0030104	water homeostasis	4/988	64/18722	0.43904790812867	0.608514692998996	HYAL2/UGCG/AKAP11/PLEC	4
GO:0030858	positive regulation of epithelial cell differentiation	4/988	64/18722	0.43904790812867	0.608514692998996	ACVRL1/NOTCH1/PRKCH/VEZF1	4
GO:0048247	lymphocyte chemotaxis	4/988	64/18722	0.43904790812867	0.608514692998996	SLC12A2/ADAM10/PLEC/WNK1	4
GO:0006516	glycoprotein catabolic process	2/988	28/18722	0.439120804226214	0.608514692998996	EDEM3/MAN1A1	2
GO:0006829	zinc ion transport	2/988	28/18722	0.439120804226214	0.608514692998996	SLC30A1/SLC30A7	2
GO:0010884	positive regulation of lipid storage	2/988	28/18722	0.439120804226214	0.608514692998996	SCARB1/CD36	2
GO:0015740	C4-dicarboxylate transport	2/988	28/18722	0.439120804226214	0.608514692998996	LRRC8C/SLC12A2	2
GO:0031440	regulation of mRNA 3'-end processing	2/988	28/18722	0.439120804226214	0.608514692998996	ZFP36L1/CCNT1	2
GO:0042983	amyloid precursor protein biosynthetic process	2/988	28/18722	0.439120804226214	0.608514692998996	ITM2A/ITM2B	2
GO:0042984	regulation of amyloid precursor protein biosynthetic process	2/988	28/18722	0.439120804226214	0.608514692998996	ITM2A/ITM2B	2
GO:0045589	regulation of regulatory T cell differentiation	2/988	28/18722	0.439120804226214	0.608514692998996	MDK/CD46	2
GO:0045686	negative regulation of glial cell differentiation	2/988	28/18722	0.439120804226214	0.608514692998996	NOTCH1/HES1	2
GO:0050996	positive regulation of lipid catabolic process	2/988	28/18722	0.439120804226214	0.608514692998996	PRKCE/CPT1A	2
GO:0051503	adenine nucleotide transport	2/988	28/18722	0.439120804226214	0.608514692998996	LRRC8C/GJA1	2
GO:0060259	regulation of feeding behavior	2/988	28/18722	0.439120804226214	0.608514692998996	LEPR/STAT3	2
GO:0060765	regulation of androgen receptor signaling pathway	2/988	28/18722	0.439120804226214	0.608514692998996	FOXP1/PKN1	2
GO:0070076	histone lysine demethylation	2/988	28/18722	0.439120804226214	0.608514692998996	KDM7A/JMJD1C	2
GO:0086011	membrane repolarization during action potential	2/988	28/18722	0.439120804226214	0.608514692998996	CAV1/FLNA	2
GO:0090659	walking behavior	2/988	28/18722	0.439120804226214	0.608514692998996	HIPK2/ZMPSTE24	2
GO:1903779	regulation of cardiac conduction	2/988	28/18722	0.439120804226214	0.608514692998996	ATP2B4/GJA5	2
GO:0031398	positive regulation of protein ubiquitination	7/988	119/18722	0.439866062083025	0.608514692998996	CAV1/FKBP1A/ANGPT1/XIAP/PTEN/CBLB/BCL10	7
GO:0007019	microtubule depolymerization	3/988	46/18722	0.440584623771986	0.608514692998996	TAOK1/APC/CAMSAP2	3
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	3/988	46/18722	0.440584623771986	0.608514692998996	SELP/HMCN1/DCHS1	3
GO:0010830	regulation of myotube differentiation	3/988	46/18722	0.440584623771986	0.608514692998996	PIEZO1/NOTCH1/ATP11A	3
GO:0031018	endocrine pancreas development	3/988	46/18722	0.440584623771986	0.608514692998996	CDK6/CLOCK/HES1	3
GO:0031057	negative regulation of histone modification	3/988	46/18722	0.440584623771986	0.608514692998996	BCOR/SKI/TRIP12	3
GO:0042398	cellular modified amino acid biosynthetic process	3/988	46/18722	0.440584623771986	0.608514692998996	MGST2/PLOD2/PLSCR1	3
GO:0048701	embryonic cranial skeleton morphogenesis	3/988	46/18722	0.440584623771986	0.608514692998996	TGFBR2/SMAD2/NIPBL	3
GO:0071827	plasma lipoprotein particle organization	3/988	46/18722	0.440584623771986	0.608514692998996	SCARB1/ACSL3/ABCA1	3
GO:0090329	regulation of DNA-dependent DNA replication	3/988	46/18722	0.440584623771986	0.608514692998996	DACH1/ATRX/ZMPSTE24	3
GO:1900271	regulation of long-term synaptic potentiation	3/988	46/18722	0.440584623771986	0.608514692998996	APP/CREB1/NPTN	3
GO:2000107	negative regulation of leukocyte apoptotic process	3/988	46/18722	0.440584623771986	0.608514692998996	FOXP1/HIF1A/BCL10	3
GO:0006576	cellular biogenic amine metabolic process	6/988	101/18722	0.443405843011359	0.608514692998996	NNMT/IDO1/NPR1/EPAS1/SLC44A1/OAZ2	6
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	8/988	138/18722	0.444553764691553	0.608514692998996	CAV1/FKBP1A/ANGPT1/XIAP/PTEN/CBLB/PIAS1/BCL10	8
GO:0000375	RNA splicing, via transesterification reactions	18/988	324/18722	0.445702131831121	0.608514692998996	NOVA2/DDX17/PABPC1/MBNL1/SETX/QKI/CELF1/SON/MBNL2/SF3B1/LUC7L3/RBM5/DYRK1A/SCAF11/HNRNPH1/HNRNPK/TIA1/PSIP1	18
GO:0051899	membrane depolarization	5/988	83/18722	0.447099986885921	0.608514692998996	EDN1/KDR/CAV1/GJA5/JUN	5
GO:0007030	Golgi organization	9/988	157/18722	0.448394953895652	0.608514692998996	HACE1/ATL3/YIPF4/CSNK1A1/ARHGEF7/TMED7/CDC42/MAPK1/CAMSAP2	9
GO:0006304	DNA modification	7/988	120/18722	0.448534917207218	0.608514692998996	KMT2E/ATRX/PIK3CA/KMT2A/ATF7IP/BAZ2A/ZMPSTE24	7
GO:0001787	natural killer cell proliferation	1/988	11/18722	0.449283626871623	0.608514692998996	HLA-E	1
GO:0001867	complement activation, lectin pathway	1/988	11/18722	0.449283626871623	0.608514692998996	A2M	1
GO:0002327	immature B cell differentiation	1/988	11/18722	0.449283626871623	0.608514692998996	IRF2BP2	1
GO:0003139	secondary heart field specification	1/988	11/18722	0.449283626871623	0.608514692998996	MEF2C	1
GO:0006054	N-acetylneuraminate metabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	ST6GAL1	1
GO:0006086	acetyl-CoA biosynthetic process from pyruvate	1/988	11/18722	0.449283626871623	0.608514692998996	PDK4	1
GO:0006182	cGMP biosynthetic process	1/988	11/18722	0.449283626871623	0.608514692998996	NPR1	1
GO:0006568	tryptophan metabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	IDO1	1
GO:0006702	androgen biosynthetic process	1/988	11/18722	0.449283626871623	0.608514692998996	SCARB1	1
GO:0006971	hypotonic response	1/988	11/18722	0.449283626871623	0.608514692998996	ITGA2	1
GO:0007144	female meiosis I	1/988	11/18722	0.449283626871623	0.608514692998996	CDC25B	1
GO:0009128	purine nucleoside monophosphate catabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	NT5E	1
GO:0009235	cobalamin metabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	CD320	1
GO:0010739	positive regulation of protein kinase A signaling	1/988	11/18722	0.449283626871623	0.608514692998996	RAMP3	1
GO:0010887	negative regulation of cholesterol storage	1/988	11/18722	0.449283626871623	0.608514692998996	ABCA1	1
GO:0014820	tonic smooth muscle contraction	1/988	11/18722	0.449283626871623	0.608514692998996	EDN1	1
GO:0015810	aspartate transmembrane transport	1/988	11/18722	0.449283626871623	0.608514692998996	LRRC8C	1
GO:0015937	coenzyme A biosynthetic process	1/988	11/18722	0.449283626871623	0.608514692998996	ACAT1	1
GO:0019048	modulation by virus of host process	1/988	11/18722	0.449283626871623	0.608514692998996	HYAL2	1
GO:0021860	pyramidal neuron development	1/988	11/18722	0.449283626871623	0.608514692998996	ZMIZ1	1
GO:0030210	heparin biosynthetic process	1/988	11/18722	0.449283626871623	0.608514692998996	ANGPT1	1
GO:0030432	peristalsis	1/988	11/18722	0.449283626871623	0.608514692998996	TBX3	1
GO:0032000	positive regulation of fatty acid beta-oxidation	1/988	11/18722	0.449283626871623	0.608514692998996	CPT1A	1
GO:0032308	positive regulation of prostaglandin secretion	1/988	11/18722	0.449283626871623	0.608514692998996	EDN1	1
GO:0032493	response to bacterial lipoprotein	1/988	11/18722	0.449283626871623	0.608514692998996	CD36	1
GO:0032610	interleukin-1 alpha production	1/988	11/18722	0.449283626871623	0.608514692998996	S100A13	1
GO:0032650	regulation of interleukin-1 alpha production	1/988	11/18722	0.449283626871623	0.608514692998996	S100A13	1
GO:0032957	inositol trisphosphate metabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	P2RY1	1
GO:0033197	response to vitamin E	1/988	11/18722	0.449283626871623	0.608514692998996	CCND1	1
GO:0033327	Leydig cell differentiation	1/988	11/18722	0.449283626871623	0.608514692998996	CCND1	1
GO:0033860	regulation of NAD(P)H oxidase activity	1/988	11/18722	0.449283626871623	0.608514692998996	GNAI2	1
GO:0034163	regulation of toll-like receptor 9 signaling pathway	1/988	11/18722	0.449283626871623	0.608514692998996	RTN4	1
GO:0034350	regulation of glial cell apoptotic process	1/988	11/18722	0.449283626871623	0.608514692998996	PRKCH	1
GO:0034379	very-low-density lipoprotein particle assembly	1/988	11/18722	0.449283626871623	0.608514692998996	ACSL3	1
GO:0034770	histone H4-K20 methylation	1/988	11/18722	0.449283626871623	0.608514692998996	KMT5B	1
GO:0035090	maintenance of apical/basal cell polarity	1/988	11/18722	0.449283626871623	0.608514692998996	PDCD6IP	1
GO:0035246	peptidyl-arginine N-methylation	1/988	11/18722	0.449283626871623	0.608514692998996	FBXO11	1
GO:0035404	histone-serine phosphorylation	1/988	11/18722	0.449283626871623	0.608514692998996	PRKAA1	1
GO:0035766	cell chemotaxis to fibroblast growth factor	1/988	11/18722	0.449283626871623	0.608514692998996	FGFR1	1
GO:0039530	MDA-5 signaling pathway	1/988	11/18722	0.449283626871623	0.608514692998996	DDX60	1
GO:0042447	hormone catabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	ECE1	1
GO:0042451	purine nucleoside biosynthetic process	1/988	11/18722	0.449283626871623	0.608514692998996	NT5E	1
GO:0042455	ribonucleoside biosynthetic process	1/988	11/18722	0.449283626871623	0.608514692998996	NT5E	1
GO:0044771	meiotic cell cycle phase transition	1/988	11/18722	0.449283626871623	0.608514692998996	CDC25B	1
GO:0045161	neuronal ion channel clustering	1/988	11/18722	0.449283626871623	0.608514692998996	AGRN	1
GO:0045199	maintenance of epithelial cell apical/basal polarity	1/988	11/18722	0.449283626871623	0.608514692998996	PDCD6IP	1
GO:0045628	regulation of T-helper 2 cell differentiation	1/988	11/18722	0.449283626871623	0.608514692998996	HLX	1
GO:0045654	positive regulation of megakaryocyte differentiation	1/988	11/18722	0.449283626871623	0.608514692998996	GATA2	1
GO:0046129	purine ribonucleoside biosynthetic process	1/988	11/18722	0.449283626871623	0.608514692998996	NT5E	1
GO:0046598	positive regulation of viral entry into host cell	1/988	11/18722	0.449283626871623	0.608514692998996	LGALS1	1
GO:0048635	negative regulation of muscle organ development	1/988	11/18722	0.449283626871623	0.608514692998996	TGFB1	1
GO:0048853	forebrain morphogenesis	1/988	11/18722	0.449283626871623	0.608514692998996	PTEN	1
GO:0051132	NK T cell activation	1/988	11/18722	0.449283626871623	0.608514692998996	HSPH1	1
GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	1/988	11/18722	0.449283626871623	0.608514692998996	ZDHHC17	1
GO:0051574	positive regulation of histone H3-K9 methylation	1/988	11/18722	0.449283626871623	0.608514692998996	RIF1	1
GO:0055015	ventricular cardiac muscle cell development	1/988	11/18722	0.449283626871623	0.608514692998996	MEF2A	1
GO:0060159	regulation of dopamine receptor signaling pathway	1/988	11/18722	0.449283626871623	0.608514692998996	CAV2	1
GO:0060174	limb bud formation	1/988	11/18722	0.449283626871623	0.608514692998996	PLXNA2	1
GO:0060379	cardiac muscle cell myoblast differentiation	1/988	11/18722	0.449283626871623	0.608514692998996	NOTCH1	1
GO:0060433	bronchus development	1/988	11/18722	0.449283626871623	0.608514692998996	TGFBR2	1
GO:0060746	parental behavior	1/988	11/18722	0.449283626871623	0.608514692998996	PTEN	1
GO:0060767	epithelial cell proliferation involved in prostate gland development	1/988	11/18722	0.449283626871623	0.608514692998996	NOTCH1	1
GO:0060900	embryonic camera-type eye formation	1/988	11/18722	0.449283626871623	0.608514692998996	PHACTR4	1
GO:0061029	eyelid development in camera-type eye	1/988	11/18722	0.449283626871623	0.608514692998996	SOS1	1
GO:0061635	regulation of protein complex stability	1/988	11/18722	0.449283626871623	0.608514692998996	TAPBP	1
GO:0070189	kynurenine metabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	IDO1	1
GO:0070243	regulation of thymocyte apoptotic process	1/988	11/18722	0.449283626871623	0.608514692998996	HIF1A	1
GO:0070314	G1 to G0 transition	1/988	11/18722	0.449283626871623	0.608514692998996	ZNF503	1
GO:0070327	thyroid hormone transport	1/988	11/18722	0.449283626871623	0.608514692998996	SLC16A2	1
GO:0070341	fat cell proliferation	1/988	11/18722	0.449283626871623	0.608514692998996	GATA2	1
GO:0070344	regulation of fat cell proliferation	1/988	11/18722	0.449283626871623	0.608514692998996	GATA2	1
GO:0070417	cellular response to cold	1/988	11/18722	0.449283626871623	0.608514692998996	FOXO1	1
GO:0071044	histone mRNA catabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	XRN1	1
GO:0071492	cellular response to UV-A	1/988	11/18722	0.449283626871623	0.608514692998996	TIMP1	1
GO:0071888	macrophage apoptotic process	1/988	11/18722	0.449283626871623	0.608514692998996	MEF2C	1
GO:0072173	metanephric tubule morphogenesis	1/988	11/18722	0.449283626871623	0.608514692998996	HES1	1
GO:0072497	mesenchymal stem cell differentiation	1/988	11/18722	0.449283626871623	0.608514692998996	LTBP3	1
GO:0075294	positive regulation by symbiont of entry into host	1/988	11/18722	0.449283626871623	0.608514692998996	LGALS1	1
GO:0086016	AV node cell action potential	1/988	11/18722	0.449283626871623	0.608514692998996	GJA5	1
GO:0086027	AV node cell to bundle of His cell signaling	1/988	11/18722	0.449283626871623	0.608514692998996	GJA5	1
GO:0086070	SA node cell to atrial cardiac muscle cell communication	1/988	11/18722	0.449283626871623	0.608514692998996	GJA5	1
GO:0090084	negative regulation of inclusion body assembly	1/988	11/18722	0.449283626871623	0.608514692998996	HSPA1A	1
GO:0090160	Golgi to lysosome transport	1/988	11/18722	0.449283626871623	0.608514692998996	LAMP1	1
GO:0090205	positive regulation of cholesterol metabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	PRKAA1	1
GO:0090219	negative regulation of lipid kinase activity	1/988	11/18722	0.449283626871623	0.608514692998996	PPP2R5A	1
GO:0090309	positive regulation of DNA methylation-dependent heterochromatin assembly	1/988	11/18722	0.449283626871623	0.608514692998996	ATF7IP	1
GO:0090394	negative regulation of excitatory postsynaptic potential	1/988	11/18722	0.449283626871623	0.608514692998996	PTEN	1
GO:0090649	response to oxygen-glucose deprivation	1/988	11/18722	0.449283626871623	0.608514692998996	BNIP2	1
GO:0097048	dendritic cell apoptotic process	1/988	11/18722	0.449283626871623	0.608514692998996	RAPGEF2	1
GO:0097090	presynaptic membrane organization	1/988	11/18722	0.449283626871623	0.608514692998996	PTEN	1
GO:0097396	response to interleukin-17	1/988	11/18722	0.449283626871623	0.608514692998996	NOTCH1	1
GO:0097398	cellular response to interleukin-17	1/988	11/18722	0.449283626871623	0.608514692998996	NOTCH1	1
GO:0097400	interleukin-17-mediated signaling pathway	1/988	11/18722	0.449283626871623	0.608514692998996	NOTCH1	1
GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	1/988	11/18722	0.449283626871623	0.608514692998996	PPP3R1	1
GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	1/988	11/18722	0.449283626871623	0.608514692998996	ITPR1	1
GO:0099624	atrial cardiac muscle cell membrane repolarization	1/988	11/18722	0.449283626871623	0.608514692998996	FLNA	1
GO:1900112	regulation of histone H3-K9 trimethylation	1/988	11/18722	0.449283626871623	0.608514692998996	ATRX	1
GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	1/988	11/18722	0.449283626871623	0.608514692998996	CD36	1
GO:1901862	negative regulation of muscle tissue development	1/988	11/18722	0.449283626871623	0.608514692998996	TGFB1	1
GO:1902188	positive regulation of viral release from host cell	1/988	11/18722	0.449283626871623	0.608514692998996	CAV2	1
GO:1902915	negative regulation of protein polyubiquitination	1/988	11/18722	0.449283626871623	0.608514692998996	TRIP12	1
GO:1903238	positive regulation of leukocyte tethering or rolling	1/988	11/18722	0.449283626871623	0.608514692998996	SELP	1
GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	1/988	11/18722	0.449283626871623	0.608514692998996	HSPA1A	1
GO:1903961	positive regulation of anion transmembrane transport	1/988	11/18722	0.449283626871623	0.608514692998996	ITGB1	1
GO:1904181	positive regulation of membrane depolarization	1/988	11/18722	0.449283626871623	0.608514692998996	KDR	1
GO:1904321	response to forskolin	1/988	11/18722	0.449283626871623	0.608514692998996	AHR	1
GO:1904322	cellular response to forskolin	1/988	11/18722	0.449283626871623	0.608514692998996	AHR	1
GO:1904847	regulation of cell chemotaxis to fibroblast growth factor	1/988	11/18722	0.449283626871623	0.608514692998996	FGFR1	1
GO:1905050	positive regulation of metallopeptidase activity	1/988	11/18722	0.449283626871623	0.608514692998996	STAT3	1
GO:1905150	regulation of voltage-gated sodium channel activity	1/988	11/18722	0.449283626871623	0.608514692998996	KIF5B	1
GO:1905522	negative regulation of macrophage migration	1/988	11/18722	0.449283626871623	0.608514692998996	CD200	1
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	1/988	11/18722	0.449283626871623	0.608514692998996	ATF6	1
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1/988	11/18722	0.449283626871623	0.608514692998996	TJP1	1
GO:2000320	negative regulation of T-helper 17 cell differentiation	1/988	11/18722	0.449283626871623	0.608514692998996	RC3H1	1
GO:2000644	regulation of receptor catabolic process	1/988	11/18722	0.449283626871623	0.608514692998996	DTX3L	1
GO:2000668	regulation of dendritic cell apoptotic process	1/988	11/18722	0.449283626871623	0.608514692998996	RAPGEF2	1
GO:0001505	regulation of neurotransmitter levels	12/988	213/18722	0.450303454412825	0.609619763327958	P2RY1/MEF2C/SYT11/ITGB1/GIT1/CALM1/STX3/SLC30A1/SNAP23/CTBP2/RAB5A/RAP1A	12
GO:0006487	protein N-linked glycosylation	4/988	65/18722	0.450902870880186	0.609619763327958	ST6GAL1/MGAT4A/MAGT1/RPN1	4
GO:0010965	regulation of mitotic sister chromatid separation	4/988	65/18722	0.450902870880186	0.609619763327958	RB1/DUSP1/APC/CDC27	4
GO:0033692	cellular polysaccharide biosynthetic process	4/988	65/18722	0.450902870880186	0.609619763327958	IGF1/IGF2/GBE1/B4GALT5	4
GO:0038034	signal transduction in absence of ligand	4/988	65/18722	0.450902870880186	0.609619763327958	FGFR1/FYN/CTNNA1/HSPA1A	4
GO:0044784	metaphase/anaphase transition of cell cycle	4/988	65/18722	0.450902870880186	0.609619763327958	RB1/DUSP1/APC/CDC27	4
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	4/988	65/18722	0.450902870880186	0.609619763327958	FGFR1/FYN/CTNNA1/HSPA1A	4
GO:0035710	CD4-positive, alpha-beta T cell activation	6/988	102/18722	0.452825949808156	0.611908279160754	HLX/FOXP1/TGFBR2/CD81/STAT3/RC3H1	6
GO:1902749	regulation of cell cycle G2/M phase transition	6/988	102/18722	0.452825949808156	0.611908279160754	APP/TAOK1/CDC25B/CCND1/RAB11A/FOXN3	6
GO:0001774	microglial cell activation	3/988	47/18722	0.454604425426255	0.613108567225842	SYT11/CLU/APP	3
GO:0032008	positive regulation of TOR signaling	3/988	47/18722	0.454604425426255	0.613108567225842	AKT3/PIK3CA/WAC	3
GO:0035315	hair cell differentiation	3/988	47/18722	0.454604425426255	0.613108567225842	JAG1/NOTCH1/HES1	3
GO:0045581	negative regulation of T cell differentiation	3/988	47/18722	0.454604425426255	0.613108567225842	HLX/MDK/RC3H1	3
GO:0047496	vesicle transport along microtubule	3/988	47/18722	0.454604425426255	0.613108567225842	KIF5B/DYNC1H1/KIFAP3	3
GO:0097028	dendritic cell differentiation	3/988	47/18722	0.454604425426255	0.613108567225842	FCGR2B/HLA-B/TGFBR2	3
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	3/988	47/18722	0.454604425426255	0.613108567225842	APLNR/THBS1/GATA2	3
GO:0002068	glandular epithelial cell development	2/988	29/18722	0.457176776126047	0.613108567225842	CDK6/CLOCK	2
GO:0002360	T cell lineage commitment	2/988	29/18722	0.457176776126047	0.613108567225842	RHOA/STAT3	2
GO:0003309	type B pancreatic cell differentiation	2/988	29/18722	0.457176776126047	0.613108567225842	CDK6/CLOCK	2
GO:0005979	regulation of glycogen biosynthetic process	2/988	29/18722	0.457176776126047	0.613108567225842	IGF1/IGF2	2
GO:0007143	female meiotic nuclear division	2/988	29/18722	0.457176776126047	0.613108567225842	CDC25B/PRKAR1A	2
GO:0010962	regulation of glucan biosynthetic process	2/988	29/18722	0.457176776126047	0.613108567225842	IGF1/IGF2	2
GO:0015868	purine ribonucleotide transport	2/988	29/18722	0.457176776126047	0.613108567225842	LRRC8C/GJA1	2
GO:0021591	ventricular system development	2/988	29/18722	0.457176776126047	0.613108567225842	CDK6/RAPGEF2	2
GO:0021602	cranial nerve morphogenesis	2/988	29/18722	0.457176776126047	0.613108567225842	NRP1/SEMA3F	2
GO:0021772	olfactory bulb development	2/988	29/18722	0.457176776126047	0.613108567225842	SKI/ID2	2
GO:0030970	retrograde protein transport, ER to cytosol	2/988	29/18722	0.457176776126047	0.613108567225842	SEL1L/HSP90B1	2
GO:0034067	protein localization to Golgi apparatus	2/988	29/18722	0.457176776126047	0.613108567225842	VPS13C/ARL5A	2
GO:0048265	response to pain	2/988	29/18722	0.457176776126047	0.613108567225842	THBS1/CAPN2	2
GO:0051654	establishment of mitochondrion localization	2/988	29/18722	0.457176776126047	0.613108567225842	ARMCX3/HIF1A	2
GO:0070979	protein K11-linked ubiquitination	2/988	29/18722	0.457176776126047	0.613108567225842	CDC27/UBE2E3	2
GO:0072539	T-helper 17 cell differentiation	2/988	29/18722	0.457176776126047	0.613108567225842	STAT3/RC3H1	2
GO:0090025	regulation of monocyte chemotaxis	2/988	29/18722	0.457176776126047	0.613108567225842	DUSP1/MOSPD2	2
GO:0090114	COPII-coated vesicle budding	2/988	29/18722	0.457176776126047	0.613108567225842	SEC23A/SEC31A	2
GO:1900117	regulation of execution phase of apoptosis	2/988	29/18722	0.457176776126047	0.613108567225842	DLC1/PAK2	2
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	2/988	29/18722	0.457176776126047	0.613108567225842	CLU/CD44	2
GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	2/988	29/18722	0.457176776126047	0.613108567225842	CD44/HNRNPK	2
GO:1903513	endoplasmic reticulum to cytosol transport	2/988	29/18722	0.457176776126047	0.613108567225842	SEL1L/HSP90B1	2
GO:1903902	positive regulation of viral life cycle	2/988	29/18722	0.457176776126047	0.613108567225842	CAV2/LGALS1	2
GO:0006405	RNA export from nucleus	5/988	84/18722	0.457504011981554	0.61323777735201	HHEX/ZC3H11A/FYTTD1/THOC2/SMG1	5
GO:0009953	dorsal/ventral pattern formation	5/988	84/18722	0.457504011981554	0.61323777735201	EDN1/ACVRL1/SMAD6/AIDA/SMAD2	5
GO:0032259	methylation	20/988	364/18722	0.459077790340478	0.615192033877048	NNMT/MECOM/BCOR/KMT2E/ATRX/PIK3CA/KMT2A/OGT/FBXO11/PCMTD1/ASH1L/WDR82/ATF7IP/KMT5B/RIF1/PCMTD2/BTG2/SMAD4/BAZ2A/ZMPSTE24	20
GO:0002440	production of molecular mediator of immune response	17/988	308/18722	0.460039136056042	0.616324814812029	FCGR2B/BST2/IL1R1/HLA-E/HLA-A/ANGPT1/B2M/CD81/PKN1/TGFB1/TNFRSF14/CD36/TMBIM6/TNFRSF1B/KMT5B/RIF1/BCL10	17
GO:0002027	regulation of heart rate	6/988	103/18722	0.46220921359477	0.618763947231708	EDN1/CAV1/PDE4D/EPAS1/ADRB1/CALM1	6
GO:0030593	neutrophil chemotaxis	6/988	103/18722	0.46220921359477	0.618763947231708	EDN1/ITGA1/MDK/JAM3/PDE4B/MOSPD2	6
GO:1905037	autophagosome organization	6/988	103/18722	0.46220921359477	0.618763947231708	FEZ2/TP53INP1/RALB/RB1CC1/SH3GLB1/RAB5A	6
GO:0006303	double-strand break repair via nonhomologous end joining	4/988	66/18722	0.462675957161034	0.61907674671018	PARP9/DTX3L/KMT5B/RIF1	4
GO:0042093	T-helper cell differentiation	4/988	66/18722	0.462675957161034	0.61907674671018	HLX/FOXP1/STAT3/RC3H1	4
GO:0007059	chromosome segregation	19/988	346/18722	0.462822672305672	0.619117107853873	RB1/TTL/DUSP1/ATRX/PDS5B/SLF2/POGZ/ACTR2/SUN1/PLSCR1/APC/STAG2/CDC27/NIPBL/RAB11A/NR3C1/PUM2/DYNC1H1/CDC42	19
GO:0032200	telomere organization	9/988	159/18722	0.463486764572654	0.61984936893503	PML/ATRX/HMBOX1/SP100/NEK7/SMG1/RIF1/MAPK1/XRN1	9
GO:0032527	protein exit from endoplasmic reticulum	3/988	48/18722	0.468474999502601	0.626047596819576	CD81/SEL1L/HSP90B1	3
GO:0090199	regulation of release of cytochrome c from mitochondria	3/988	48/18722	0.468474999502601	0.626047596819576	IGF1/TNFSF10/CLU	3
GO:1905710	positive regulation of membrane permeability	3/988	48/18722	0.468474999502601	0.626047596819576	JAM3/ATF2/HSPA1A	3
GO:0032006	regulation of TOR signaling	6/988	104/18722	0.471551075381042	0.626340962638438	AKT3/PIK3CA/HIF1A/PRKAA1/WAC/ZMPSTE24	6
GO:0045621	positive regulation of lymphocyte differentiation	6/988	104/18722	0.471551075381042	0.626340962638438	HLX/TGFBR2/MDK/RHOA/ZMIZ1/CD46	6
GO:0007416	synapse assembly	10/988	179/18722	0.472992068194679	0.626340962638438	ADGRL2/EFNB2/MEF2C/PLXND1/AGRN/PDLIM5/APP/PTEN/SDCBP/NPTN	10
GO:0032890	regulation of organic acid transport	4/988	67/18722	0.474359132180977	0.626340962638438	EDN1/THBS1/ITGB1/SLC12A2	4
GO:0051306	mitotic sister chromatid separation	4/988	67/18722	0.474359132180977	0.626340962638438	RB1/DUSP1/APC/CDC27	4
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	4/988	67/18722	0.474359132180977	0.626340962638438	HLX/TGFBR2/CD81/RC3H1	4
GO:0048167	regulation of synaptic plasticity	11/988	198/18722	0.474702508325123	0.626340962638438	MEF2C/APP/STX3/PTEN/CREB1/NPTN/RAPGEF2/RAB11A/MAPK1/PLK2/RAB5A	11
GO:0000132	establishment of mitotic spindle orientation	2/988	30/18722	0.474891191259441	0.626340962638438	ITGB1/GJA1	2
GO:0006884	cell volume homeostasis	2/988	30/18722	0.474891191259441	0.626340962638438	SLC12A2/CLCN3	2
GO:0015721	bile acid and bile salt transport	2/988	30/18722	0.474891191259441	0.626340962638438	CEACAM1/PRKAA1	2
GO:0015865	purine nucleotide transport	2/988	30/18722	0.474891191259441	0.626340962638438	LRRC8C/GJA1	2
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	2/988	30/18722	0.474891191259441	0.626340962638438	FCGR2B/B2M	2
GO:0030204	chondroitin sulfate metabolic process	2/988	30/18722	0.474891191259441	0.626340962638438	NDNF/CHSY1	2
GO:0032480	negative regulation of type I interferon production	2/988	30/18722	0.474891191259441	0.626340962638438	CYLD/REL	2
GO:0043032	positive regulation of macrophage activation	2/988	30/18722	0.474891191259441	0.626340962638438	IL33/THBS1	2
GO:0043304	regulation of mast cell degranulation	2/988	30/18722	0.474891191259441	0.626340962638438	FOXF1/GATA2	2
GO:0045940	positive regulation of steroid metabolic process	2/988	30/18722	0.474891191259441	0.626340962638438	STARD4/PRKAA1	2
GO:0060292	long-term synaptic depression	2/988	30/18722	0.474891191259441	0.626340962638438	PTEN/PLK2	2
GO:0060603	mammary gland duct morphogenesis	2/988	30/18722	0.474891191259441	0.626340962638438	PML/TBX3	2
GO:1903019	negative regulation of glycoprotein metabolic process	2/988	30/18722	0.474891191259441	0.626340962638438	ITM2A/ITM2B	2
GO:0006493	protein O-linked glycosylation	5/988	86/18722	0.478138398263835	0.626340962638438	EOGT/ST6GAL1/OGT/B4GALT5/TMTC3	5
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	1/988	12/18722	0.478363193792195	0.626340962638438	RPS6KA2	1
GO:0002024	diet induced thermogenesis	1/988	12/18722	0.478363193792195	0.626340962638438	ADRB1	1
GO:0006563	L-serine metabolic process	1/988	12/18722	0.478363193792195	0.626340962638438	SERINC3	1
GO:0009086	methionine biosynthetic process	1/988	12/18722	0.478363193792195	0.626340962638438	MRI1	1
GO:0010454	negative regulation of cell fate commitment	1/988	12/18722	0.478363193792195	0.626340962638438	HES1	1
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	1/988	12/18722	0.478363193792195	0.626340962638438	PTPN12	1
GO:0014831	gastro-intestinal system smooth muscle contraction	1/988	12/18722	0.478363193792195	0.626340962638438	SULF2	1
GO:0021670	lateral ventricle development	1/988	12/18722	0.478363193792195	0.626340962638438	CDK6	1
GO:0030157	pancreatic juice secretion	1/988	12/18722	0.478363193792195	0.626340962638438	WNK1	1
GO:0030202	heparin metabolic process	1/988	12/18722	0.478363193792195	0.626340962638438	ANGPT1	1
GO:0031453	positive regulation of heterochromatin assembly	1/988	12/18722	0.478363193792195	0.626340962638438	ATF7IP	1
GO:0032306	regulation of prostaglandin secretion	1/988	12/18722	0.478363193792195	0.626340962638438	EDN1	1
GO:0032490	detection of molecule of bacterial origin	1/988	12/18722	0.478363193792195	0.626340962638438	SCARB1	1
GO:0032736	positive regulation of interleukin-13 production	1/988	12/18722	0.478363193792195	0.626340962638438	HLA-E	1
GO:0032780	negative regulation of ATPase activity	1/988	12/18722	0.478363193792195	0.626340962638438	CNN3	1
GO:0032782	bile acid secretion	1/988	12/18722	0.478363193792195	0.626340962638438	PRKAA1	1
GO:0032908	regulation of transforming growth factor beta1 production	1/988	12/18722	0.478363193792195	0.626340962638438	THBS1	1
GO:0032926	negative regulation of activin receptor signaling pathway	1/988	12/18722	0.478363193792195	0.626340962638438	SKI	1
GO:0033004	negative regulation of mast cell activation	1/988	12/18722	0.478363193792195	0.626340962638438	FOXF1	1
GO:0033182	regulation of histone ubiquitination	1/988	12/18722	0.478363193792195	0.626340962638438	TRIP12	1
GO:0033235	positive regulation of protein sumoylation	1/988	12/18722	0.478363193792195	0.626340962638438	PIAS1	1
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	1/988	12/18722	0.478363193792195	0.626340962638438	WDFY1	1
GO:0035112	genitalia morphogenesis	1/988	12/18722	0.478363193792195	0.626340962638438	NIPBL	1
GO:0042762	regulation of sulfur metabolic process	1/988	12/18722	0.478363193792195	0.626340962638438	PDK4	1
GO:0043380	regulation of memory T cell differentiation	1/988	12/18722	0.478363193792195	0.626340962638438	CD46	1
GO:0043471	regulation of cellular carbohydrate catabolic process	1/988	12/18722	0.478363193792195	0.626340962638438	SCARB2	1
GO:0044650	adhesion of symbiont to host cell	1/988	12/18722	0.478363193792195	0.626340962638438	CD81	1
GO:0051255	spindle midzone assembly	1/988	12/18722	0.478363193792195	0.626340962638438	CCDC69	1
GO:0051340	regulation of ligase activity	1/988	12/18722	0.478363193792195	0.626340962638438	TMSB4X	1
GO:0051549	positive regulation of keratinocyte migration	1/988	12/18722	0.478363193792195	0.626340962638438	MAP4K4	1
GO:0051639	actin filament network formation	1/988	12/18722	0.478363193792195	0.626340962638438	PLS3	1
GO:0060134	prepulse inhibition	1/988	12/18722	0.478363193792195	0.626340962638438	PTEN	1
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	1/988	12/18722	0.478363193792195	0.626340962638438	SMAD6	1
GO:0060788	ectodermal placode formation	1/988	12/18722	0.478363193792195	0.626340962638438	TBX3	1
GO:0060907	positive regulation of macrophage cytokine production	1/988	12/18722	0.478363193792195	0.626340962638438	CD36	1
GO:0070170	regulation of tooth mineralization	1/988	12/18722	0.478363193792195	0.626340962638438	BCOR	1
GO:0070493	thrombin-activated receptor signaling pathway	1/988	12/18722	0.478363193792195	0.626340962638438	F2R	1
GO:0070857	regulation of bile acid biosynthetic process	1/988	12/18722	0.478363193792195	0.626340962638438	STARD4	1
GO:0071257	cellular response to electrical stimulus	1/988	12/18722	0.478363193792195	0.626340962638438	PTEN	1
GO:0071287	cellular response to manganese ion	1/988	12/18722	0.478363193792195	0.626340962638438	APP	1
GO:0071472	cellular response to salt stress	1/988	12/18722	0.478363193792195	0.626340962638438	ZFP36L1	1
GO:0071635	negative regulation of transforming growth factor beta production	1/988	12/18722	0.478363193792195	0.626340962638438	FN1	1
GO:0071697	ectodermal placode morphogenesis	1/988	12/18722	0.478363193792195	0.626340962638438	TBX3	1
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1/988	12/18722	0.478363193792195	0.626340962638438	WWTR1	1
GO:0072537	fibroblast activation	1/988	12/18722	0.478363193792195	0.626340962638438	RGCC	1
GO:0072711	cellular response to hydroxyurea	1/988	12/18722	0.478363193792195	0.626340962638438	ATRX	1
GO:0086067	AV node cell to bundle of His cell communication	1/988	12/18722	0.478363193792195	0.626340962638438	GJA5	1
GO:0090677	reversible differentiation	1/988	12/18722	0.478363193792195	0.626340962638438	PDGFB	1
GO:0098911	regulation of ventricular cardiac muscle cell action potential	1/988	12/18722	0.478363193792195	0.626340962638438	CAV1	1
GO:0120263	positive regulation of heterochromatin organization	1/988	12/18722	0.478363193792195	0.626340962638438	ATF7IP	1
GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	1/988	12/18722	0.478363193792195	0.626340962638438	CD36	1
GO:1902563	regulation of neutrophil activation	1/988	12/18722	0.478363193792195	0.626340962638438	FCGR2B	1
GO:1903599	positive regulation of autophagy of mitochondrion	1/988	12/18722	0.478363193792195	0.626340962638438	HIF1A	1
GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	1/988	12/18722	0.478363193792195	0.626340962638438	TGFB1	1
GO:1904953	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	1/988	12/18722	0.478363193792195	0.626340962638438	LRP6	1
GO:1990034	calcium ion export across plasma membrane	1/988	12/18722	0.478363193792195	0.626340962638438	CALM1	1
GO:2000105	positive regulation of DNA-dependent DNA replication	1/988	12/18722	0.478363193792195	0.626340962638438	ATRX	1
GO:2000303	regulation of ceramide biosynthetic process	1/988	12/18722	0.478363193792195	0.626340962638438	PRKAA1	1
GO:2000317	negative regulation of T-helper 17 type immune response	1/988	12/18722	0.478363193792195	0.626340962638438	RC3H1	1
GO:2000344	positive regulation of acrosome reaction	1/988	12/18722	0.478363193792195	0.626340962638438	PLCB1	1
GO:2000628	regulation of miRNA metabolic process	1/988	12/18722	0.478363193792195	0.626340962638438	RC3H1	1
GO:0007033	vacuole organization	10/988	180/18722	0.480081367848745	0.628435738297816	SCARB2/FEZ2/TP53INP1/LYST/RALB/ABCA1/RB1CC1/ATF2/SH3GLB1/RAB5A	10
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	3/988	49/18722	0.482185198840614	0.629792912771414	TGFB1/KMT5B/RIF1	3
GO:0002208	somatic diversification of immunoglobulins involved in immune response	3/988	49/18722	0.482185198840614	0.629792912771414	TGFB1/KMT5B/RIF1	3
GO:0002762	negative regulation of myeloid leukocyte differentiation	3/988	49/18722	0.482185198840614	0.629792912771414	CEACAM1/CDK6/GATA2	3
GO:0006692	prostanoid metabolic process	3/988	49/18722	0.482185198840614	0.629792912771414	EDN1/FABP5/ZADH2	3
GO:0006693	prostaglandin metabolic process	3/988	49/18722	0.482185198840614	0.629792912771414	EDN1/FABP5/ZADH2	3
GO:0006953	acute-phase response	3/988	49/18722	0.482185198840614	0.629792912771414	FN1/STAT3/PLSCR1	3
GO:0009994	oocyte differentiation	3/988	49/18722	0.482185198840614	0.629792912771414	IGF1/RPS6KA2/CDC25B	3
GO:0043330	response to exogenous dsRNA	3/988	49/18722	0.482185198840614	0.629792912771414	CAV1/RALB/MAPK1	3
GO:0045190	isotype switching	3/988	49/18722	0.482185198840614	0.629792912771414	TGFB1/KMT5B/RIF1	3
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	4/988	68/18722	0.485944813673109	0.633768438554273	HLX/FOXP1/STAT3/RC3H1	4
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	4/988	68/18722	0.485944813673109	0.633768438554273	TMSB4X/TGFB1/STAT3/ATP6V1A	4
GO:0009247	glycolipid biosynthetic process	4/988	68/18722	0.485944813673109	0.633768438554273	UGCG/ST3GAL5/PRKAA1/B4GALT5	4
GO:0046637	regulation of alpha-beta T cell differentiation	4/988	68/18722	0.485944813673109	0.633768438554273	HLX/TGFBR2/RHOA/RC3H1	4
GO:0061912	selective autophagy	4/988	68/18722	0.485944813673109	0.633768438554273	SPTLC2/RB1CC1/VPS13C/WDFY3	4
GO:1904888	cranial skeletal system development	4/988	68/18722	0.485944813673109	0.633768438554273	TGFBR2/SMAD2/NIPBL/FOXN3	4
GO:1901606	alpha-amino acid catabolic process	5/988	87/18722	0.48835744879909	0.636758656853404	IDO1/GLS/DDAH2/ACAT1/ATP2B4	5
GO:0035821	modulation of process of other organism	6/988	106/18722	0.490093125769302	0.63823063347275	IFI27/HYAL2/CAV2/STOM/JUN/CCNT1	6
GO:0070585	protein localization to mitochondrion	7/988	125/18722	0.491432150594941	0.63823063347275	ABLIM3/CALM1/ISG15/LEPROT/PRKAA1/RALA/SH3GLB1	7
GO:0001516	prostaglandin biosynthetic process	2/988	31/18722	0.492249793926555	0.63823063347275	EDN1/FABP5	2
GO:0002230	positive regulation of defense response to virus by host	2/988	31/18722	0.492249793926555	0.63823063347275	PARP9/DTX3L	2
GO:0002323	natural killer cell activation involved in immune response	2/988	31/18722	0.492249793926555	0.63823063347275	LAMP1/RAB27A	2
GO:0002717	positive regulation of natural killer cell mediated immunity	2/988	31/18722	0.492249793926555	0.63823063347275	HLA-E/LAMP1	2
GO:0002828	regulation of type 2 immune response	2/988	31/18722	0.492249793926555	0.63823063347275	HLX/CD81	2
GO:0006301	postreplication repair	2/988	31/18722	0.492249793926555	0.63823063347275	REV3L/POLK	2
GO:0007190	activation of adenylate cyclase activity	2/988	31/18722	0.492249793926555	0.63823063347275	ADRB1/CALM1	2
GO:0008045	motor neuron axon guidance	2/988	31/18722	0.492249793926555	0.63823063347275	NRP1/SEMA3F	2
GO:0016577	histone demethylation	2/988	31/18722	0.492249793926555	0.63823063347275	KDM7A/JMJD1C	2
GO:0021988	olfactory lobe development	2/988	31/18722	0.492249793926555	0.63823063347275	SKI/ID2	2
GO:0033006	regulation of mast cell activation involved in immune response	2/988	31/18722	0.492249793926555	0.63823063347275	FOXF1/GATA2	2
GO:0033238	regulation of cellular amine metabolic process	2/988	31/18722	0.492249793926555	0.63823063347275	NNMT/ATP2B4	2
GO:0036475	neuron death in response to oxidative stress	2/988	31/18722	0.492249793926555	0.63823063347275	NCOA7/HIF1A	2
GO:0045066	regulatory T cell differentiation	2/988	31/18722	0.492249793926555	0.63823063347275	MDK/CD46	2
GO:0046457	prostanoid biosynthetic process	2/988	31/18722	0.492249793926555	0.63823063347275	EDN1/FABP5	2
GO:0065005	protein-lipid complex assembly	2/988	31/18722	0.492249793926555	0.63823063347275	ACSL3/ABCA1	2
GO:0071168	protein localization to chromatin	2/988	31/18722	0.492249793926555	0.63823063347275	RB1/NIPBL	2
GO:0071480	cellular response to gamma radiation	2/988	31/18722	0.492249793926555	0.63823063347275	EGR1/ZMPSTE24	2
GO:1900027	regulation of ruffle assembly	2/988	31/18722	0.492249793926555	0.63823063347275	CAV1/RDX	2
GO:1901797	negative regulation of signal transduction by p53 class mediator	2/988	31/18722	0.492249793926555	0.63823063347275	CD44/DYRK1A	2
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	2/988	31/18722	0.492249793926555	0.63823063347275	PEA15/CFLAR	2
GO:0046394	carboxylic acid biosynthetic process	17/988	314/18722	0.492406281263408	0.638277736962232	EDN1/CEACAM1/FABP5/MGST2/SERINC3/PDK4/GLS/MRI1/LPGAT1/PLOD2/ACSL3/ELOVL5/QKI/HSD17B12/ATP2B4/STARD4/PRKAA1	17
GO:0051260	protein homooligomerization	10/988	182/18722	0.494196500536732	0.640442012893662	KCTD12/B2M/ATL3/GLS/PKD2/TNFAIP1/EHD4/PDCD6IP/RNF213/BCL10	10
GO:0043268	positive regulation of potassium ion transport	3/988	50/18722	0.49572482345352	0.641796310549622	KIF5B/FLNA/WNK1	3
GO:0046638	positive regulation of alpha-beta T cell differentiation	3/988	50/18722	0.49572482345352	0.641796310549622	HLX/TGFBR2/RHOA	3
GO:0051646	mitochondrion localization	3/988	50/18722	0.49572482345352	0.641796310549622	MEF2A/ARMCX3/HIF1A	3
GO:0071825	protein-lipid complex subunit organization	3/988	50/18722	0.49572482345352	0.641796310549622	SCARB1/ACSL3/ABCA1	3
GO:0002287	alpha-beta T cell activation involved in immune response	4/988	69/18722	0.497425866574683	0.642901752614286	HLX/FOXP1/STAT3/RC3H1	4
GO:0002293	alpha-beta T cell differentiation involved in immune response	4/988	69/18722	0.497425866574683	0.642901752614286	HLX/FOXP1/STAT3/RC3H1	4
GO:0007004	telomere maintenance via telomerase	4/988	69/18722	0.497425866574683	0.642901752614286	HMBOX1/NEK7/MAPK1/XRN1	4
GO:0009145	purine nucleoside triphosphate biosynthetic process	4/988	69/18722	0.497425866574683	0.642901752614286	TMSB4X/TGFB1/STAT3/ATP6V1A	4
GO:0019226	transmission of nerve impulse	4/988	69/18722	0.497425866574683	0.642901752614286	S1PR1/ITGA2/JAM3/PLEC	4
GO:0034605	cellular response to heat	4/988	69/18722	0.497425866574683	0.642901752614286	CD34/THBS1/ATXN3/HSPA1A	4
GO:0050810	regulation of steroid biosynthetic process	4/988	69/18722	0.497425866574683	0.642901752614286	IGFBP7/EGR1/STARD4/PRKAA1	4
GO:0010876	lipid localization	24/988	448/18722	0.499930328308061	0.643685562983536	EDN1/FABP4/LRP6/PLSCR4/CEACAM1/FZD4/CAV1/SLCO2A1/SCARB1/FABP5/THBS1/UGCG/CLU/ATP11A/SCARB2/OSBPL10/CPT1A/ACSL3/CD36/ABCA1/PLSCR1/SLC2A1/STARD4/PRKAA1	24
GO:0000819	sister chromatid segregation	11/988	202/18722	0.501559587353065	0.643685562983536	RB1/DUSP1/ATRX/PDS5B/SLF2/POGZ/APC/STAG2/CDC27/NIPBL/RAB11A	11
GO:0008406	gonad development	12/988	221/18722	0.501869871296661	0.643685562983536	FZD4/TNFSF10/ADAM15/ATRX/FLNA/RNF38/FNDC3A/CSDE1/NR2F2/CTNNA1/CCND1/SMAD4	12
GO:0070085	glycosylation	13/988	240/18722	0.502155351807224	0.643685562983536	EOGT/ST6GAL1/ST3GAL5/FUT11/MGAT4A/OGT/EDEM3/MAN1A1/MAGT1/DPY19L4/B4GALT5/RPN1/TMTC3	13
GO:0016053	organic acid biosynthetic process	17/988	316/18722	0.503124036910077	0.643685562983536	EDN1/CEACAM1/FABP5/MGST2/SERINC3/PDK4/GLS/MRI1/LPGAT1/PLOD2/ACSL3/ELOVL5/QKI/HSD17B12/ATP2B4/STARD4/PRKAA1	17
GO:0002087	regulation of respiratory gaseous exchange by nervous system process	1/988	13/18722	0.505908739731977	0.643685562983536	GLS	1
GO:0002551	mast cell chemotaxis	1/988	13/18722	0.505908739731977	0.643685562983536	VEGFC	1
GO:0005513	detection of calcium ion	1/988	13/18722	0.505908739731977	0.643685562983536	CALM1	1
GO:0006361	transcription initiation from RNA polymerase I promoter	1/988	13/18722	0.505908739731977	0.643685562983536	BAZ2A	1
GO:0006586	indolalkylamine metabolic process	1/988	13/18722	0.505908739731977	0.643685562983536	IDO1	1
GO:0007494	midgut development	1/988	13/18722	0.505908739731977	0.643685562983536	FOXF1	1
GO:0007512	adult heart development	1/988	13/18722	0.505908739731977	0.643685562983536	APLNR	1
GO:0007567	parturition	1/988	13/18722	0.505908739731977	0.643685562983536	EDN1	1
GO:0009437	carnitine metabolic process	1/988	13/18722	0.505908739731977	0.643685562983536	CPT1A	1
GO:0010635	regulation of mitochondrial fusion	1/988	13/18722	0.505908739731977	0.643685562983536	VAT1	1
GO:0010745	negative regulation of macrophage derived foam cell differentiation	1/988	13/18722	0.505908739731977	0.643685562983536	ABCA1	1
GO:0010958	regulation of amino acid import across plasma membrane	1/988	13/18722	0.505908739731977	0.643685562983536	ITGB1	1
GO:0014029	neural crest formation	1/988	13/18722	0.505908739731977	0.643685562983536	LRP6	1
GO:0016078	tRNA catabolic process	1/988	13/18722	0.505908739731977	0.643685562983536	DICER1	1
GO:0021514	ventral spinal cord interneuron differentiation	1/988	13/18722	0.505908739731977	0.643685562983536	GATA2	1
GO:0021681	cerebellar granular layer development	1/988	13/18722	0.505908739731977	0.643685562983536	MDK	1
GO:0021859	pyramidal neuron differentiation	1/988	13/18722	0.505908739731977	0.643685562983536	ZMIZ1	1
GO:0021984	adenohypophysis development	1/988	13/18722	0.505908739731977	0.643685562983536	HES1	1
GO:0030497	fatty acid elongation	1/988	13/18722	0.505908739731977	0.643685562983536	ELOVL5	1
GO:0030836	positive regulation of actin filament depolymerization	1/988	13/18722	0.505908739731977	0.643685562983536	DSTN	1
GO:0031392	regulation of prostaglandin biosynthetic process	1/988	13/18722	0.505908739731977	0.643685562983536	FABP5	1
GO:0032252	secretory granule localization	1/988	13/18722	0.505908739731977	0.643685562983536	KIF5B	1
GO:0032905	transforming growth factor beta1 production	1/988	13/18722	0.505908739731977	0.643685562983536	THBS1	1
GO:0033689	negative regulation of osteoblast proliferation	1/988	13/18722	0.505908739731977	0.643685562983536	EIF2AK2	1
GO:0033700	phospholipid efflux	1/988	13/18722	0.505908739731977	0.643685562983536	ABCA1	1
GO:0034135	regulation of toll-like receptor 2 signaling pathway	1/988	13/18722	0.505908739731977	0.643685562983536	PJA2	1
GO:0035745	T-helper 2 cell cytokine production	1/988	13/18722	0.505908739731977	0.643685562983536	CD81	1
GO:0036462	TRAIL-activated apoptotic signaling pathway	1/988	13/18722	0.505908739731977	0.643685562983536	PTEN	1
GO:0042761	very long-chain fatty acid biosynthetic process	1/988	13/18722	0.505908739731977	0.643685562983536	ELOVL5	1
GO:0043247	telomere maintenance in response to DNA damage	1/988	13/18722	0.505908739731977	0.643685562983536	RIF1	1
GO:0043379	memory T cell differentiation	1/988	13/18722	0.505908739731977	0.643685562983536	CD46	1
GO:0043928	exonucleolytic catabolism of deadenylated mRNA	1/988	13/18722	0.505908739731977	0.643685562983536	CNOT8	1
GO:0046512	sphingosine biosynthetic process	1/988	13/18722	0.505908739731977	0.643685562983536	SPTLC2	1
GO:0046520	sphingoid biosynthetic process	1/988	13/18722	0.505908739731977	0.643685562983536	SPTLC2	1
GO:0048012	hepatocyte growth factor receptor signaling pathway	1/988	13/18722	0.505908739731977	0.643685562983536	NRP1	1
GO:0051451	myoblast migration	1/988	13/18722	0.505908739731977	0.643685562983536	ROCK1	1
GO:0051481	negative regulation of cytosolic calcium ion concentration	1/988	13/18722	0.505908739731977	0.643685562983536	GTF2I	1
GO:0055062	phosphate ion homeostasis	1/988	13/18722	0.505908739731977	0.643685562983536	XPR1	1
GO:0061744	motor behavior	1/988	13/18722	0.505908739731977	0.643685562983536	PRKAA1	1
GO:0070234	positive regulation of T cell apoptotic process	1/988	13/18722	0.505908739731977	0.643685562983536	IDO1	1
GO:0070254	mucus secretion	1/988	13/18722	0.505908739731977	0.643685562983536	PRKCE	1
GO:0071027	nuclear RNA surveillance	1/988	13/18722	0.505908739731977	0.643685562983536	XRN1	1
GO:0071028	nuclear mRNA surveillance	1/988	13/18722	0.505908739731977	0.643685562983536	XRN1	1
GO:0072506	trivalent inorganic anion homeostasis	1/988	13/18722	0.505908739731977	0.643685562983536	XPR1	1
GO:0072710	response to hydroxyurea	1/988	13/18722	0.505908739731977	0.643685562983536	ATRX	1
GO:0090153	regulation of sphingolipid biosynthetic process	1/988	13/18722	0.505908739731977	0.643685562983536	PRKAA1	1
GO:0090158	endoplasmic reticulum membrane organization	1/988	13/18722	0.505908739731977	0.643685562983536	RTN4	1
GO:0097154	GABAergic neuron differentiation	1/988	13/18722	0.505908739731977	0.643685562983536	GATA2	1
GO:0098840	protein transport along microtubule	1/988	13/18722	0.505908739731977	0.643685562983536	KIF5B	1
GO:0099118	microtubule-based protein transport	1/988	13/18722	0.505908739731977	0.643685562983536	KIF5B	1
GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	1/988	13/18722	0.505908739731977	0.643685562983536	ATF6	1
GO:1900272	negative regulation of long-term synaptic potentiation	1/988	13/18722	0.505908739731977	0.643685562983536	APP	1
GO:1903789	regulation of amino acid transmembrane transport	1/988	13/18722	0.505908739731977	0.643685562983536	ITGB1	1
GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	1/988	13/18722	0.505908739731977	0.643685562983536	VPS13C	1
GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	1/988	13/18722	0.505908739731977	0.643685562983536	KLF4	1
GO:1905038	regulation of membrane lipid metabolic process	1/988	13/18722	0.505908739731977	0.643685562983536	PRKAA1	1
GO:1905064	negative regulation of vascular associated smooth muscle cell differentiation	1/988	13/18722	0.505908739731977	0.643685562983536	PDGFB	1
GO:1905269	positive regulation of chromatin organization	1/988	13/18722	0.505908739731977	0.643685562983536	ATF7IP	1
GO:1905907	negative regulation of amyloid fibril formation	1/988	13/18722	0.505908739731977	0.643685562983536	CLU	1
GO:2000551	regulation of T-helper 2 cell cytokine production	1/988	13/18722	0.505908739731977	0.643685562983536	CD81	1
GO:0098659	inorganic cation import across plasma membrane	6/988	108/18722	0.508418727014079	0.645451449699225	RAMP3/SLC12A2/FYN/SLC30A1/ATP2B4/WNK1	6
GO:0099587	inorganic ion import across plasma membrane	6/988	108/18722	0.508418727014079	0.645451449699225	RAMP3/SLC12A2/FYN/SLC30A1/ATP2B4/WNK1	6
GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	4/988	70/18722	0.508795596633975	0.645451449699225	B2M/TGFB1/KMT5B/RIF1	4
GO:0006636	unsaturated fatty acid biosynthetic process	3/988	51/18722	0.509084585649168	0.645451449699225	EDN1/FABP5/ELOVL5	3
GO:0065002	intracellular protein transmembrane transport	3/988	51/18722	0.509084585649168	0.645451449699225	TRAM1/SEC62/SEC61A1	3
GO:1903307	positive regulation of regulated secretory pathway	3/988	51/18722	0.509084585649168	0.645451449699225	LAMP1/RAB27A/GATA2	3
GO:0003338	metanephros morphogenesis	2/988	32/18722	0.509240780438526	0.645451449699225	PKD2/HES1	2
GO:0033687	osteoblast proliferation	2/988	32/18722	0.509240780438526	0.645451449699225	RHOA/EIF2AK2	2
GO:0045684	positive regulation of epidermis development	2/988	32/18722	0.509240780438526	0.645451449699225	NOTCH1/PRKCH	2
GO:0046475	glycerophospholipid catabolic process	2/988	32/18722	0.509240780438526	0.645451449699225	ENPP2/SCARB1	2
GO:0046856	phosphatidylinositol dephosphorylation	2/988	32/18722	0.509240780438526	0.645451449699225	PTEN/MTMR6	2
GO:0050850	positive regulation of calcium-mediated signaling	2/988	32/18722	0.509240780438526	0.645451449699225	IGF1/LMCD1	2
GO:0061037	negative regulation of cartilage development	2/988	32/18722	0.509240780438526	0.645451449699225	EFEMP1/LTBP3	2
GO:0072337	modified amino acid transport	2/988	32/18722	0.509240780438526	0.645451449699225	SLC38A2/GJA1	2
GO:2000191	regulation of fatty acid transport	2/988	32/18722	0.509240780438526	0.645451449699225	EDN1/THBS1	2
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	2/988	32/18722	0.509240780438526	0.645451449699225	HLX/RC3H1	2
GO:0035278	miRNA mediated inhibition of translation	5/988	90/18722	0.51855942526205	0.656792481400098	ZFP36/STAT3/TNRC6B/DDX6/TNRC6A	5
GO:0040033	negative regulation of translation, ncRNA-mediated	5/988	90/18722	0.51855942526205	0.656792481400098	ZFP36/STAT3/TNRC6B/DDX6/TNRC6A	5
GO:0042475	odontogenesis of dentin-containing tooth	5/988	90/18722	0.51855942526205	0.656792481400098	FOXO1/HTRA1/CTNNA1/ATF2/ANKRD11	5
GO:0072078	nephron tubule morphogenesis	4/988	71/18722	0.520047743055095	0.658520527081922	DCHS1/PKD2/HES1/SMAD4	4
GO:0002218	activation of innate immune response	3/988	52/18722	0.522256074407576	0.659815526290589	IFI16/FYN/PAK2	3
GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	3/988	52/18722	0.522256074407576	0.659815526290589	PLPP3/TAPBP/ERGIC1	3
GO:0021545	cranial nerve development	3/988	52/18722	0.522256074407576	0.659815526290589	NRP1/SEMA3F/HES1	3
GO:0043277	apoptotic cell clearance	3/988	52/18722	0.522256074407576	0.659815526290589	SCARB1/THBS1/CD36	3
GO:0042886	amide transport	16/988	301/18722	0.524841972731304	0.659815526290589	EDN1/CRHBP/NNAT/PRKCE/KIF5B/CPT1A/GJA1/HIF1A/MAP4K4/ABCA1/TAPBP/CLOCK/PPP3CA/PIM3/SMAD2/MIDN	16
GO:0001881	receptor recycling	2/988	33/18722	0.525854580481079	0.659815526290589	RAMP3/ECE1	2
GO:0006336	DNA replication-independent nucleosome assembly	2/988	33/18722	0.525854580481079	0.659815526290589	ATRX/UBN2	2
GO:0006482	protein demethylation	2/988	33/18722	0.525854580481079	0.659815526290589	KDM7A/JMJD1C	2
GO:0008214	protein dealkylation	2/988	33/18722	0.525854580481079	0.659815526290589	KDM7A/JMJD1C	2
GO:0018345	protein palmitoylation	2/988	33/18722	0.525854580481079	0.659815526290589	ZDHHC17/GOLGA7	2
GO:0046320	regulation of fatty acid oxidation	2/988	33/18722	0.525854580481079	0.659815526290589	PDK4/CPT1A	2
GO:0046685	response to arsenic-containing substance	2/988	33/18722	0.525854580481079	0.659815526290589	SLC38A2/PTEN	2
GO:0048730	epidermis morphogenesis	2/988	33/18722	0.525854580481079	0.659815526290589	NOTCH1/KLF4	2
GO:0050974	detection of mechanical stimulus involved in sensory perception	2/988	33/18722	0.525854580481079	0.659815526290589	ITGA2/FYN	2
GO:0071353	cellular response to interleukin-4	2/988	33/18722	0.525854580481079	0.659815526290589	PML/PARP14	2
GO:0110110	positive regulation of animal organ morphogenesis	2/988	33/18722	0.525854580481079	0.659815526290589	CD34/EDN1	2
GO:1901976	regulation of cell cycle checkpoint	2/988	33/18722	0.525854580481079	0.659815526290589	DUSP1/FEM1B	2
GO:0006885	regulation of pH	5/988	91/18722	0.52845909100471	0.659815526290589	EDN1/PDK4/CLIC4/CLCN3/MAPK1	5
GO:0045974	regulation of translation, ncRNA-mediated	5/988	91/18722	0.52845909100471	0.659815526290589	ZFP36/STAT3/TNRC6B/DDX6/TNRC6A	5
GO:0060191	regulation of lipase activity	5/988	91/18722	0.52845909100471	0.659815526290589	BICD1/PCSK5/FGFR1/GNAQ/RHOA	5
GO:0033045	regulation of sister chromatid segregation	4/988	72/18722	0.531176470286529	0.659815526290589	RB1/DUSP1/APC/CDC27	4
GO:1905039	carboxylic acid transmembrane transport	8/988	149/18722	0.531564071573517	0.659815526290589	LRRC8C/THBS1/SLC38A2/ITGB1/CPT1A/CD36/SLC2A1/SLC16A2	8
GO:0000054	ribosomal subunit export from nucleus	1/988	14/18722	0.532001110523832	0.659815526290589	XPO1	1
GO:0002091	negative regulation of receptor internalization	1/988	14/18722	0.532001110523832	0.659815526290589	SDCBP	1
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1/988	14/18722	0.532001110523832	0.659815526290589	PRKCE	1
GO:0002829	negative regulation of type 2 immune response	1/988	14/18722	0.532001110523832	0.659815526290589	HLX	1
GO:0003376	sphingosine-1-phosphate receptor signaling pathway	1/988	14/18722	0.532001110523832	0.659815526290589	S1PR1	1
GO:0006521	regulation of cellular amino acid metabolic process	1/988	14/18722	0.532001110523832	0.659815526290589	ATP2B4	1
GO:0006999	nuclear pore organization	1/988	14/18722	0.532001110523832	0.659815526290589	RTN4	1
GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	1/988	14/18722	0.532001110523832	0.659815526290589	ANGPT1	1
GO:0009158	ribonucleoside monophosphate catabolic process	1/988	14/18722	0.532001110523832	0.659815526290589	NT5E	1
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1/988	14/18722	0.532001110523832	0.659815526290589	ACTN4	1
GO:0010838	positive regulation of keratinocyte proliferation	1/988	14/18722	0.532001110523832	0.659815526290589	MDK	1
GO:0010839	negative regulation of keratinocyte proliferation	1/988	14/18722	0.532001110523832	0.659815526290589	CD109	1
GO:0010867	positive regulation of triglyceride biosynthetic process	1/988	14/18722	0.532001110523832	0.659815526290589	SCARB1	1
GO:0010872	regulation of cholesterol esterification	1/988	14/18722	0.532001110523832	0.659815526290589	STARD4	1
GO:0022038	corpus callosum development	1/988	14/18722	0.532001110523832	0.659815526290589	NIN	1
GO:0030007	cellular potassium ion homeostasis	1/988	14/18722	0.532001110523832	0.659815526290589	SLC12A2	1
GO:0030049	muscle filament sliding	1/988	14/18722	0.532001110523832	0.659815526290589	MYL6	1
GO:0032688	negative regulation of interferon-beta production	1/988	14/18722	0.532001110523832	0.659815526290589	REL	1
GO:0032966	negative regulation of collagen biosynthetic process	1/988	14/18722	0.532001110523832	0.659815526290589	RAP1A	1
GO:0033008	positive regulation of mast cell activation involved in immune response	1/988	14/18722	0.532001110523832	0.659815526290589	GATA2	1
GO:0033750	ribosome localization	1/988	14/18722	0.532001110523832	0.659815526290589	XPO1	1
GO:0035437	maintenance of protein localization in endoplasmic reticulum	1/988	14/18722	0.532001110523832	0.659815526290589	GJA1	1
GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	1/988	14/18722	0.532001110523832	0.659815526290589	P2RY1	1
GO:0035630	bone mineralization involved in bone maturation	1/988	14/18722	0.532001110523832	0.659815526290589	IGF1	1
GO:0035672	oligopeptide transmembrane transport	1/988	14/18722	0.532001110523832	0.659815526290589	GJA1	1
GO:0038183	bile acid signaling pathway	1/988	14/18722	0.532001110523832	0.659815526290589	PRKAA1	1
GO:0042415	norepinephrine metabolic process	1/988	14/18722	0.532001110523832	0.659815526290589	EPAS1	1
GO:0043306	positive regulation of mast cell degranulation	1/988	14/18722	0.532001110523832	0.659815526290589	GATA2	1
GO:0043455	regulation of secondary metabolic process	1/988	14/18722	0.532001110523832	0.659815526290589	RAPGEF2	1
GO:0043558	regulation of translational initiation in response to stress	1/988	14/18722	0.532001110523832	0.659815526290589	EIF2AK2	1
GO:0043650	dicarboxylic acid biosynthetic process	1/988	14/18722	0.532001110523832	0.659815526290589	GLS	1
GO:0043922	negative regulation by host of viral transcription	1/988	14/18722	0.532001110523832	0.659815526290589	JUN	1
GO:0044154	histone H3-K14 acetylation	1/988	14/18722	0.532001110523832	0.659815526290589	KMT2A	1
GO:0046325	negative regulation of glucose import	1/988	14/18722	0.532001110523832	0.659815526290589	PEA15	1
GO:0048021	regulation of melanin biosynthetic process	1/988	14/18722	0.532001110523832	0.659815526290589	RAPGEF2	1
GO:0048681	negative regulation of axon regeneration	1/988	14/18722	0.532001110523832	0.659815526290589	PTEN	1
GO:0050930	induction of positive chemotaxis	1/988	14/18722	0.532001110523832	0.659815526290589	VEGFC	1
GO:0051645	Golgi localization	1/988	14/18722	0.532001110523832	0.659815526290589	CDC42	1
GO:0060732	positive regulation of inositol phosphate biosynthetic process	1/988	14/18722	0.532001110523832	0.659815526290589	P2RY1	1
GO:0060911	cardiac cell fate commitment	1/988	14/18722	0.532001110523832	0.659815526290589	TBX3	1
GO:0061043	regulation of vascular wound healing	1/988	14/18722	0.532001110523832	0.659815526290589	SLC12A2	1
GO:0061709	reticulophagy	1/988	14/18722	0.532001110523832	0.659815526290589	RB1CC1	1
GO:0070986	left/right axis specification	1/988	14/18722	0.532001110523832	0.659815526290589	NOTCH1	1
GO:0071285	cellular response to lithium ion	1/988	14/18722	0.532001110523832	0.659815526290589	FABP4	1
GO:0071415	cellular response to purine-containing compound	1/988	14/18722	0.532001110523832	0.659815526290589	P2RY1	1
GO:0071481	cellular response to X-ray	1/988	14/18722	0.532001110523832	0.659815526290589	NIPBL	1
GO:0072176	nephric duct development	1/988	14/18722	0.532001110523832	0.659815526290589	PKD2	1
GO:0072540	T-helper 17 cell lineage commitment	1/988	14/18722	0.532001110523832	0.659815526290589	STAT3	1
GO:0090128	regulation of synapse maturation	1/988	14/18722	0.532001110523832	0.659815526290589	ARHGEF15	1
GO:0090239	regulation of histone H4 acetylation	1/988	14/18722	0.532001110523832	0.659815526290589	ZMPSTE24	1
GO:0090281	negative regulation of calcium ion import	1/988	14/18722	0.532001110523832	0.659815526290589	SLC30A1	1
GO:0090308	regulation of DNA methylation-dependent heterochromatin assembly	1/988	14/18722	0.532001110523832	0.659815526290589	ATF7IP	1
GO:0090715	immunological memory formation process	1/988	14/18722	0.532001110523832	0.659815526290589	CD46	1
GO:0097091	synaptic vesicle clustering	1/988	14/18722	0.532001110523832	0.659815526290589	PTEN	1
GO:0097531	mast cell migration	1/988	14/18722	0.532001110523832	0.659815526290589	VEGFC	1
GO:0099638	endosome to plasma membrane protein transport	1/988	14/18722	0.532001110523832	0.659815526290589	RAB11A	1
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	1/988	14/18722	0.532001110523832	0.659815526290589	ACTN4	1
GO:1900376	regulation of secondary metabolite biosynthetic process	1/988	14/18722	0.532001110523832	0.659815526290589	RAPGEF2	1
GO:1901857	positive regulation of cellular respiration	1/988	14/18722	0.532001110523832	0.659815526290589	IFNAR1	1
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	1/988	14/18722	0.532001110523832	0.659815526290589	CD44	1
GO:1902916	positive regulation of protein polyubiquitination	1/988	14/18722	0.532001110523832	0.659815526290589	XIAP	1
GO:1902969	mitotic DNA replication	1/988	14/18722	0.532001110523832	0.659815526290589	ZMPSTE24	1
GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	1/988	14/18722	0.532001110523832	0.659815526290589	VPS13C	1
GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	1/988	14/18722	0.532001110523832	0.659815526290589	ENG	1
GO:1905208	negative regulation of cardiocyte differentiation	1/988	14/18722	0.532001110523832	0.659815526290589	SMAD4	1
GO:2001256	regulation of store-operated calcium entry	1/988	14/18722	0.532001110523832	0.659815526290589	SARAF	1
GO:0006814	sodium ion transport	13/988	245/18722	0.532537326704573	0.660326395764401	PRKCE/SLC38A2/UTRN/KIF5B/STOM/ACTN4/SLC12A2/PKD2/FXYD5/ATP2B4/WNK1/MAGED2/NEDD4	13
GO:0030534	adult behavior	7/988	130/18722	0.533273350544117	0.66108472300825	CRHBP/PREX2/HIPK2/APP/PTEN/CLCN3/ZMPSTE24	7
GO:0016064	immunoglobulin mediated immune response	11/988	207/18722	0.534605736157678	0.662581817655059	FCGR2B/CFI/HLA-E/CLU/B2M/CD81/TGFB1/CD46/KMT5B/RIF1/BCL10	11
GO:0033059	cellular pigmentation	3/988	53/18722	0.535231719283856	0.662893656525028	LYST/RAB27A/RAB11A	3
GO:0051438	regulation of ubiquitin-protein transferase activity	3/988	53/18722	0.535231719283856	0.662893656525028	PTEN/FEM1B/DTX3L	3
GO:1903202	negative regulation of oxidative stress-induced cell death	3/988	53/18722	0.535231719283856	0.662893656525028	FYN/NCOA7/HIF1A	3
GO:0015718	monocarboxylic acid transport	6/988	111/18722	0.535434487563237	0.662990209309071	EDN1/CEACAM1/SLCO2A1/CD36/PRKAA1/SLC16A2	6
GO:1903312	negative regulation of mRNA metabolic process	5/988	92/18722	0.538267577536185	0.666342897196974	PABPC1/ZFP36/DYRK1A/HNRNPK/CCNT1	5
GO:1903825	organic acid transmembrane transport	8/988	150/18722	0.53924277712906	0.667394602075854	LRRC8C/THBS1/SLC38A2/ITGB1/CPT1A/CD36/SLC2A1/SLC16A2	8
GO:0045089	positive regulation of innate immune response	7/988	131/18722	0.541481061487253	0.668843664489307	HLA-E/IFI16/FYN/LAMP1/PARP9/PLSCR1/PAK2	7
GO:0050853	B cell receptor signaling pathway	7/988	131/18722	0.541481061487253	0.668843664489307	FCGR2B/MEF2C/FOXP1/CD81/PRKCH/CMTM3/MAPK1	7
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	2/988	34/18722	0.542083654687597	0.668843664489307	FCGR2B/B2M	2
GO:0006356	regulation of transcription by RNA polymerase I	2/988	34/18722	0.542083654687597	0.668843664489307	FLNA/ZMPSTE24	2
GO:0007095	mitotic G2 DNA damage checkpoint signaling	2/988	34/18722	0.542083654687597	0.668843664489307	TAOK1/FOXN3	2
GO:0010661	positive regulation of muscle cell apoptotic process	2/988	34/18722	0.542083654687597	0.668843664489307	PTEN/CAPN2	2
GO:0031128	developmental induction	2/988	34/18722	0.542083654687597	0.668843664489307	HIPK2/HIPK1	2
GO:0034724	DNA replication-independent nucleosome organization	2/988	34/18722	0.542083654687597	0.668843664489307	ATRX/UBN2	2
GO:0035137	hindlimb morphogenesis	2/988	34/18722	0.542083654687597	0.668843664489307	NOTCH1/TBX3	2
GO:0035590	purinergic nucleotide receptor signaling pathway	2/988	34/18722	0.542083654687597	0.668843664489307	P2RY1/GNAI2	2
GO:0048536	spleen development	2/988	34/18722	0.542083654687597	0.668843664489307	PKN1/RC3H1	2
GO:0050931	pigment cell differentiation	2/988	34/18722	0.542083654687597	0.668843664489307	MEF2C/RAB27A	2
GO:2000780	negative regulation of double-strand break repair	2/988	34/18722	0.542083654687597	0.668843664489307	TRIP12/RIF1	2
GO:0072088	nephron epithelium morphogenesis	4/988	73/18722	0.542176359053267	0.668843664489307	DCHS1/PKD2/HES1/SMAD4	4
GO:0009141	nucleoside triphosphate metabolic process	6/988	112/18722	0.544299703186019	0.67130717978271	GIMAP7/TMSB4X/TGFB1/RHOA/STAT3/ATP6V1A	6
GO:0055067	monovalent inorganic cation homeostasis	8/988	151/18722	0.546872342133286	0.674323556502325	EDN1/NPR1/PDK4/GNAI2/SLC12A2/CLIC4/CLCN3/MAPK1	8
GO:0030520	intracellular estrogen receptor signaling pathway	3/988	54/18722	0.548004754074237	0.675093055111862	DDX17/CNOT2/ARID1A	3
GO:0043647	inositol phosphate metabolic process	3/988	54/18722	0.548004754074237	0.675093055111862	P2RY1/NUDT3/PTEN	3
GO:0070839	metal ion export	3/988	54/18722	0.548004754074237	0.675093055111862	CALM1/ATP2B4/ATOX1	3
GO:0072698	protein localization to microtubule cytoskeleton	3/988	54/18722	0.548004754074237	0.675093055111862	BICD1/PCM1/APC	3
GO:0006801	superoxide metabolic process	4/988	74/18722	0.55304239672645	0.675252516859623	EDN1/GNAI2/TGFB1/CD36	4
GO:0009201	ribonucleoside triphosphate biosynthetic process	4/988	74/18722	0.55304239672645	0.675252516859623	TMSB4X/TGFB1/STAT3/ATP6V1A	4
GO:0030968	endoplasmic reticulum unfolded protein response	4/988	74/18722	0.55304239672645	0.675252516859623	ERO1A/EIF2AK2/CCND1/ATF6	4
GO:0019724	B cell mediated immunity	11/988	210/18722	0.55407745928778	0.675252516859623	FCGR2B/CFI/HLA-E/CLU/B2M/CD81/TGFB1/CD46/KMT5B/RIF1/BCL10	11
GO:0002730	regulation of dendritic cell cytokine production	1/988	15/18722	0.556716895364673	0.675252516859623	BST2	1
GO:0006089	lactate metabolic process	1/988	15/18722	0.556716895364673	0.675252516859623	HIF1A	1
GO:0006684	sphingomyelin metabolic process	1/988	15/18722	0.556716895364673	0.675252516859623	SPTLC2	1
GO:0006825	copper ion transport	1/988	15/18722	0.556716895364673	0.675252516859623	ATOX1	1
GO:0006878	cellular copper ion homeostasis	1/988	15/18722	0.556716895364673	0.675252516859623	APP	1
GO:0007000	nucleolus organization	1/988	15/18722	0.556716895364673	0.675252516859623	BAZ2A	1
GO:0009083	branched-chain amino acid catabolic process	1/988	15/18722	0.556716895364673	0.675252516859623	ACAT1	1
GO:0009163	nucleoside biosynthetic process	1/988	15/18722	0.556716895364673	0.675252516859623	NT5E	1
GO:0010713	negative regulation of collagen metabolic process	1/988	15/18722	0.556716895364673	0.675252516859623	RAP1A	1
GO:0010832	negative regulation of myotube differentiation	1/988	15/18722	0.556716895364673	0.675252516859623	NOTCH1	1
GO:0014733	regulation of skeletal muscle adaptation	1/988	15/18722	0.556716895364673	0.675252516859623	PPP3CA	1
GO:0014744	positive regulation of muscle adaptation	1/988	15/18722	0.556716895364673	0.675252516859623	PPP3CA	1
GO:0015697	quaternary ammonium group transport	1/988	15/18722	0.556716895364673	0.675252516859623	SLC38A2	1
GO:0018216	peptidyl-arginine methylation	1/988	15/18722	0.556716895364673	0.675252516859623	FBXO11	1
GO:0018410	C-terminal protein amino acid modification	1/988	15/18722	0.556716895364673	0.675252516859623	TTL	1
GO:0030852	regulation of granulocyte differentiation	1/988	15/18722	0.556716895364673	0.675252516859623	CEACAM1	1
GO:0032310	prostaglandin secretion	1/988	15/18722	0.556716895364673	0.675252516859623	EDN1	1
GO:0032328	alanine transport	1/988	15/18722	0.556716895364673	0.675252516859623	SLC38A2	1
GO:0032354	response to follicle-stimulating hormone	1/988	15/18722	0.556716895364673	0.675252516859623	NOTCH1	1
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	1/988	15/18722	0.556716895364673	0.675252516859623	CNOT2	1
GO:0033275	actin-myosin filament sliding	1/988	15/18722	0.556716895364673	0.675252516859623	MYL6	1
GO:0034380	high-density lipoprotein particle assembly	1/988	15/18722	0.556716895364673	0.675252516859623	ABCA1	1
GO:0034384	high-density lipoprotein particle clearance	1/988	15/18722	0.556716895364673	0.675252516859623	SCARB1	1
GO:0034404	nucleobase-containing small molecule biosynthetic process	1/988	15/18722	0.556716895364673	0.675252516859623	NT5E	1
GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	1/988	15/18722	0.556716895364673	0.675252516859623	FABP5	1
GO:0035435	phosphate ion transmembrane transport	1/988	15/18722	0.556716895364673	0.675252516859623	XPR1	1
GO:0035493	SNARE complex assembly	1/988	15/18722	0.556716895364673	0.675252516859623	STXBP6	1
GO:0036124	histone H3-K9 trimethylation	1/988	15/18722	0.556716895364673	0.675252516859623	ATRX	1
GO:0043252	sodium-independent organic anion transport	1/988	15/18722	0.556716895364673	0.675252516859623	SLCO2A1	1
GO:0043584	nose development	1/988	15/18722	0.556716895364673	0.675252516859623	SKI	1
GO:0045064	T-helper 2 cell differentiation	1/988	15/18722	0.556716895364673	0.675252516859623	HLX	1
GO:0045836	positive regulation of meiotic nuclear division	1/988	15/18722	0.556716895364673	0.675252516859623	PLCB1	1
GO:0046321	positive regulation of fatty acid oxidation	1/988	15/18722	0.556716895364673	0.675252516859623	CPT1A	1
GO:0046500	S-adenosylmethionine metabolic process	1/988	15/18722	0.556716895364673	0.675252516859623	MRI1	1
GO:0046834	lipid phosphorylation	1/988	15/18722	0.556716895364673	0.675252516859623	DGKH	1
GO:0048308	organelle inheritance	1/988	15/18722	0.556716895364673	0.675252516859623	MAPK1	1
GO:0048313	Golgi inheritance	1/988	15/18722	0.556716895364673	0.675252516859623	MAPK1	1
GO:0051290	protein heterotetramerization	1/988	15/18722	0.556716895364673	0.675252516859623	PKD2	1
GO:0051775	response to redox state	1/988	15/18722	0.556716895364673	0.675252516859623	CLOCK	1
GO:0051938	L-glutamate import	1/988	15/18722	0.556716895364673	0.675252516859623	ITGB1	1
GO:0055091	phospholipid homeostasis	1/988	15/18722	0.556716895364673	0.675252516859623	ABCA1	1
GO:0060046	regulation of acrosome reaction	1/988	15/18722	0.556716895364673	0.675252516859623	PLCB1	1
GO:0060413	atrial septum morphogenesis	1/988	15/18722	0.556716895364673	0.675252516859623	BMPR2	1
GO:0060766	negative regulation of androgen receptor signaling pathway	1/988	15/18722	0.556716895364673	0.675252516859623	FOXP1	1
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1/988	15/18722	0.556716895364673	0.675252516859623	CD81	1
GO:0071025	RNA surveillance	1/988	15/18722	0.556716895364673	0.675252516859623	XRN1	1
GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	1/988	15/18722	0.556716895364673	0.675252516859623	XPO1	1
GO:0071474	cellular hyperosmotic response	1/988	15/18722	0.556716895364673	0.675252516859623	SLC2A1	1
GO:0072044	collecting duct development	1/988	15/18722	0.556716895364673	0.675252516859623	NOTCH1	1
GO:0086069	bundle of His cell to Purkinje myocyte communication	1/988	15/18722	0.556716895364673	0.675252516859623	GJA5	1
GO:0098712	L-glutamate import across plasma membrane	1/988	15/18722	0.556716895364673	0.675252516859623	ITGB1	1
GO:0110156	methylguanosine-cap decapping	1/988	15/18722	0.556716895364673	0.675252516859623	ZFP36	1
GO:1902018	negative regulation of cilium assembly	1/988	15/18722	0.556716895364673	0.675252516859623	MAP4	1
GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	1/988	15/18722	0.556716895364673	0.675252516859623	SESTD1	1
GO:1902902	negative regulation of autophagosome assembly	1/988	15/18722	0.556716895364673	0.675252516859623	FEZ2	1
GO:1904251	regulation of bile acid metabolic process	1/988	15/18722	0.556716895364673	0.675252516859623	STARD4	1
GO:1905168	positive regulation of double-strand break repair via homologous recombination	1/988	15/18722	0.556716895364673	0.675252516859623	ACTR2	1
GO:1905288	vascular associated smooth muscle cell apoptotic process	1/988	15/18722	0.556716895364673	0.675252516859623	IGF1	1
GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	1/988	15/18722	0.556716895364673	0.675252516859623	IGF1	1
GO:2000052	positive regulation of non-canonical Wnt signaling pathway	1/988	15/18722	0.556716895364673	0.675252516859623	RSPO3	1
GO:2001279	regulation of unsaturated fatty acid biosynthetic process	1/988	15/18722	0.556716895364673	0.675252516859623	FABP5	1
GO:0000731	DNA synthesis involved in DNA repair	2/988	35/18722	0.557922307322456	0.675252516859623	REV3L/POLK	2
GO:0006471	protein ADP-ribosylation	2/988	35/18722	0.557922307322456	0.675252516859623	PARP14/PARP9	2
GO:0032814	regulation of natural killer cell activation	2/988	35/18722	0.557922307322456	0.675252516859623	HLA-E/LAMP1	2
GO:0040001	establishment of mitotic spindle localization	2/988	35/18722	0.557922307322456	0.675252516859623	ITGB1/GJA1	2
GO:0043243	positive regulation of protein-containing complex disassembly	2/988	35/18722	0.557922307322456	0.675252516859623	SETX/DSTN	2
GO:0044273	sulfur compound catabolic process	2/988	35/18722	0.557922307322456	0.675252516859623	GNS/ACAT1	2
GO:0045454	cell redox homeostasis	2/988	35/18722	0.557922307322456	0.675252516859623	GIT1/ERO1A	2
GO:0045880	positive regulation of smoothened signaling pathway	2/988	35/18722	0.557922307322456	0.675252516859623	CHSY1/CTNNA1	2
GO:0050654	chondroitin sulfate proteoglycan metabolic process	2/988	35/18722	0.557922307322456	0.675252516859623	NDNF/CHSY1	2
GO:0060236	regulation of mitotic spindle organization	2/988	35/18722	0.557922307322456	0.675252516859623	DYNC1H1/HSPA1A	2
GO:0070536	protein K63-linked deubiquitination	2/988	35/18722	0.557922307322456	0.675252516859623	ATXN3/CYLD	2
GO:0097502	mannosylation	2/988	35/18722	0.557922307322456	0.675252516859623	DPY19L4/TMTC3	2
GO:0006360	transcription by RNA polymerase I	3/988	55/18722	0.560569180454539	0.677838262366154	FLNA/BAZ2A/ZMPSTE24	3
GO:0008333	endosome to lysosome transport	3/988	55/18722	0.560569180454539	0.677838262366154	RHOB/LYST/DTX3L	3
GO:0043331	response to dsRNA	3/988	55/18722	0.560569180454539	0.677838262366154	CAV1/RALB/MAPK1	3
GO:0061098	positive regulation of protein tyrosine kinase activity	3/988	55/18722	0.560569180454539	0.677838262366154	NEDD9/PDGFB/PAK2	3
GO:0019751	polyol metabolic process	6/988	114/18722	0.561800974439454	0.679018606649005	P2RY1/PLPP1/SPTLC2/PLPP3/NUDT3/PTEN	6
GO:0046660	female sex differentiation	6/988	114/18722	0.561800974439454	0.679018606649005	DACH1/FZD4/NR2F2/TBX3/CTNNA1/SMAD4	6
GO:0006024	glycosaminoglycan biosynthetic process	4/988	75/18722	0.563769967118755	0.681088484269917	ANGPT1/PDGFB/CHSY1/TGFB1	4
GO:0006278	RNA-dependent DNA biosynthetic process	4/988	75/18722	0.563769967118755	0.681088484269917	HMBOX1/NEK7/MAPK1/XRN1	4
GO:0001508	action potential	7/988	134/18722	0.565734683574235	0.683306648282477	CAV1/GNAQ/CALM1/GJA1/FLNA/CD36/GJA5	7
GO:0006694	steroid biosynthetic process	9/988	173/18722	0.565950046366153	0.683411376744034	HSD17B2/SCARB1/IGFBP7/HSD17B12/EGR1/LBR/STARD4/PRKAA1/CYB5R3	9
GO:0032479	regulation of type I interferon production	5/988	95/18722	0.567106724300664	0.68449691422066	OAS2/ISG15/CYLD/G3BP1/REL	5
GO:0032606	type I interferon production	5/988	95/18722	0.567106724300664	0.68449691422066	OAS2/ISG15/CYLD/G3BP1/REL	5
GO:0042471	ear morphogenesis	6/988	115/18722	0.570431210901742	0.688040552295653	EDN1/TSHZ1/GATA2/FZD6/NIPBL/MAPK1	6
GO:0043279	response to alkaloid	6/988	115/18722	0.570431210901742	0.688040552295653	CRHBP/PRKCE/PEA15/CPT1A/PPP2R2A/PRKAA1	6
GO:0046916	cellular transition metal ion homeostasis	6/988	115/18722	0.570431210901742	0.688040552295653	APP/HIF1A/ATP6V1A/SLC30A1/SLC30A7/SMAD4	6
GO:0001658	branching involved in ureteric bud morphogenesis	3/988	56/18722	0.572919731774655	0.688921718457514	DCHS1/PKD2/SMAD4	3
GO:0030166	proteoglycan biosynthetic process	3/988	56/18722	0.572919731774655	0.688921718457514	IGF1/BMPR2/CHSY1	3
GO:0032608	interferon-beta production	3/988	56/18722	0.572919731774655	0.688921718457514	OAS2/ISG15/REL	3
GO:0032648	regulation of interferon-beta production	3/988	56/18722	0.572919731774655	0.688921718457514	OAS2/ISG15/REL	3
GO:0046456	icosanoid biosynthetic process	3/988	56/18722	0.572919731774655	0.688921718457514	EDN1/FABP5/MGST2	3
GO:0007584	response to nutrient	9/988	174/18722	0.572966693292199	0.688921718457514	SPARC/ITGA2/TGFBR2/GNAI2/ACSL3/PTEN/OGT/ABCA1/CCND1	9
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	2/988	36/18722	0.57336651304606	0.688921718457514	KIF5B/HIF1A	2
GO:0042092	type 2 immune response	2/988	36/18722	0.57336651304606	0.688921718457514	HLX/CD81	2
GO:0042119	neutrophil activation	2/988	36/18722	0.57336651304606	0.688921718457514	FCGR2B/KMT2E	2
GO:0045738	negative regulation of DNA repair	2/988	36/18722	0.57336651304606	0.688921718457514	TRIP12/RIF1	2
GO:0045746	negative regulation of Notch signaling pathway	2/988	36/18722	0.57336651304606	0.688921718457514	EGFL7/GATA2	2
GO:0046466	membrane lipid catabolic process	2/988	36/18722	0.57336651304606	0.688921718457514	ENPP2/MGST2	2
GO:0051354	negative regulation of oxidoreductase activity	2/988	36/18722	0.57336651304606	0.688921718457514	CAV1/ATP2B4	2
GO:0051955	regulation of amino acid transport	2/988	36/18722	0.57336651304606	0.688921718457514	ITGB1/SLC12A2	2
GO:0060338	regulation of type I interferon-mediated signaling pathway	2/988	36/18722	0.57336651304606	0.688921718457514	ISG15/ADAR	2
GO:0070670	response to interleukin-4	2/988	36/18722	0.57336651304606	0.688921718457514	PML/PARP14	2
GO:0070873	regulation of glycogen metabolic process	2/988	36/18722	0.57336651304606	0.688921718457514	IGF1/IGF2	2
GO:0009581	detection of external stimulus	7/988	135/18722	0.573687996714727	0.688943302617876	FOXF1/ITGA2/PIEZO1/GNAQ/FYN/PKD2/PTK2	7
GO:0032720	negative regulation of tumor necrosis factor production	4/988	76/18722	0.574354839788133	0.688943302617876	CD34/IGF1/SYT11/DICER1	4
GO:0072028	nephron morphogenesis	4/988	76/18722	0.574354839788133	0.688943302617876	DCHS1/PKD2/HES1/SMAD4	4
GO:0051304	chromosome separation	5/988	96/18722	0.576512442984292	0.688943302617876	RB1/DUSP1/PLSCR1/APC/CDC27	5
GO:0072330	monocarboxylic acid biosynthetic process	11/988	214/18722	0.579544370705508	0.688943302617876	EDN1/CEACAM1/FABP5/PDK4/LPGAT1/ACSL3/ELOVL5/QKI/HSD17B12/STARD4/PRKAA1	11
GO:0002371	dendritic cell cytokine production	1/988	16/18722	0.580128650717199	0.688943302617876	BST2	1
GO:0002399	MHC class II protein complex assembly	1/988	16/18722	0.580128650717199	0.688943302617876	B2M	1
GO:0002503	peptide antigen assembly with MHC class II protein complex	1/988	16/18722	0.580128650717199	0.688943302617876	B2M	1
GO:0002566	somatic diversification of immune receptors via somatic mutation	1/988	16/18722	0.580128650717199	0.688943302617876	ADAR	1
GO:0002827	positive regulation of T-helper 1 type immune response	1/988	16/18722	0.580128650717199	0.688943302617876	IL1R1	1
GO:0002830	positive regulation of type 2 immune response	1/988	16/18722	0.580128650717199	0.688943302617876	CD81	1
GO:0005980	glycogen catabolic process	1/988	16/18722	0.580128650717199	0.688943302617876	RB1CC1	1
GO:0006206	pyrimidine nucleobase metabolic process	1/988	16/18722	0.580128650717199	0.688943302617876	MAPK1	1
GO:0006555	methionine metabolic process	1/988	16/18722	0.580128650717199	0.688943302617876	MRI1	1
GO:0006750	glutathione biosynthetic process	1/988	16/18722	0.580128650717199	0.688943302617876	MGST2	1
GO:0006857	oligopeptide transport	1/988	16/18722	0.580128650717199	0.688943302617876	GJA1	1
GO:0009074	aromatic amino acid family catabolic process	1/988	16/18722	0.580128650717199	0.688943302617876	IDO1	1
GO:0010225	response to UV-C	1/988	16/18722	0.580128650717199	0.688943302617876	CARD16	1
GO:0010919	regulation of inositol phosphate biosynthetic process	1/988	16/18722	0.580128650717199	0.688943302617876	P2RY1	1
GO:0014061	regulation of norepinephrine secretion	1/988	16/18722	0.580128650717199	0.688943302617876	P2RY1	1
GO:0016584	nucleosome positioning	1/988	16/18722	0.580128650717199	0.688943302617876	RSF1	1
GO:0030540	female genitalia development	1/988	16/18722	0.580128650717199	0.688943302617876	TBX3	1
GO:0034116	positive regulation of heterotypic cell-cell adhesion	1/988	16/18722	0.580128650717199	0.688943302617876	CD44	1
GO:0034375	high-density lipoprotein particle remodeling	1/988	16/18722	0.580128650717199	0.688943302617876	SCARB1	1
GO:0044065	regulation of respiratory system process	1/988	16/18722	0.580128650717199	0.688943302617876	GLS	1
GO:0044804	autophagy of nucleus	1/988	16/18722	0.580128650717199	0.688943302617876	RB1CC1	1
GO:0045721	negative regulation of gluconeogenesis	1/988	16/18722	0.580128650717199	0.688943302617876	LEPR	1
GO:0048311	mitochondrion distribution	1/988	16/18722	0.580128650717199	0.688943302617876	MEF2A	1
GO:0050884	neuromuscular process controlling posture	1/988	16/18722	0.580128650717199	0.688943302617876	TCF15	1
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	1/988	16/18722	0.580128650717199	0.688943302617876	TNFRSF1B	1
GO:0051238	sequestering of metal ion	1/988	16/18722	0.580128650717199	0.688943302617876	SLC30A7	1
GO:0051969	regulation of transmission of nerve impulse	1/988	16/18722	0.580128650717199	0.688943302617876	ITGA2	1
GO:0055089	fatty acid homeostasis	1/988	16/18722	0.580128650717199	0.688943302617876	PRKAA1	1
GO:0061684	chaperone-mediated autophagy	1/988	16/18722	0.580128650717199	0.688943302617876	CLU	1
GO:0070230	positive regulation of lymphocyte apoptotic process	1/988	16/18722	0.580128650717199	0.688943302617876	IDO1	1
GO:0070242	thymocyte apoptotic process	1/988	16/18722	0.580128650717199	0.688943302617876	HIF1A	1
GO:0070365	hepatocyte differentiation	1/988	16/18722	0.580128650717199	0.688943302617876	ITGA2	1
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	1/988	16/18722	0.580128650717199	0.688943302617876	HSPA1A	1
GO:0071391	cellular response to estrogen stimulus	1/988	16/18722	0.580128650717199	0.688943302617876	CRHBP	1
GO:0090231	regulation of spindle checkpoint	1/988	16/18722	0.580128650717199	0.688943302617876	DUSP1	1
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	1/988	16/18722	0.580128650717199	0.688943302617876	DUSP1	1
GO:0090520	sphingolipid mediated signaling pathway	1/988	16/18722	0.580128650717199	0.688943302617876	S1PR1	1
GO:0097202	activation of cysteine-type endopeptidase activity	1/988	16/18722	0.580128650717199	0.688943302617876	IFI16	1
GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	1/988	16/18722	0.580128650717199	0.688943302617876	P2RY1	1
GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway	1/988	16/18722	0.580128650717199	0.688943302617876	ADGRA2	1
GO:1903236	regulation of leukocyte tethering or rolling	1/988	16/18722	0.580128650717199	0.688943302617876	SELP	1
GO:1903504	regulation of mitotic spindle checkpoint	1/988	16/18722	0.580128650717199	0.688943302617876	DUSP1	1
GO:1904948	midbrain dopaminergic neuron differentiation	1/988	16/18722	0.580128650717199	0.688943302617876	LRP6	1
GO:2000001	regulation of DNA damage checkpoint	1/988	16/18722	0.580128650717199	0.688943302617876	FEM1B	1
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	1/988	16/18722	0.580128650717199	0.688943302617876	RSPO3	1
GO:2000765	regulation of cytoplasmic translation	1/988	16/18722	0.580128650717199	0.688943302617876	CNBP	1
GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1/988	16/18722	0.580128650717199	0.688943302617876	GSN	1
GO:0002200	somatic diversification of immune receptors	4/988	77/18722	0.584793158927116	0.693704321214893	TGFB1/ADAR/KMT5B/RIF1	4
GO:0006367	transcription initiation from RNA polymerase II promoter	4/988	77/18722	0.584793158927116	0.693704321214893	THRA/CREB1/MED13/ATF7IP	4
GO:0006695	cholesterol biosynthetic process	3/988	57/18722	0.585051837169187	0.693704321214893	LBR/PRKAA1/CYB5R3	3
GO:0016447	somatic recombination of immunoglobulin gene segments	3/988	57/18722	0.585051837169187	0.693704321214893	TGFB1/KMT5B/RIF1	3
GO:0051289	protein homotetramerization	3/988	57/18722	0.585051837169187	0.693704321214893	B2M/GLS/PKD2	3
GO:1902017	regulation of cilium assembly	3/988	57/18722	0.585051837169187	0.693704321214893	CYLD/CCDC88A/MAP4	3
GO:1902653	secondary alcohol biosynthetic process	3/988	57/18722	0.585051837169187	0.693704321214893	LBR/PRKAA1/CYB5R3	3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2/988	37/18722	0.588413756799337	0.696136720738992	PABPC1/SMG1	2
GO:0003016	respiratory system process	2/988	37/18722	0.588413756799337	0.696136720738992	TCF15/GLS	2
GO:0006862	nucleotide transport	2/988	37/18722	0.588413756799337	0.696136720738992	LRRC8C/GJA1	2
GO:0006904	vesicle docking involved in exocytosis	2/988	37/18722	0.588413756799337	0.696136720738992	RALB/CTBP2	2
GO:0042401	cellular biogenic amine biosynthetic process	2/988	37/18722	0.588413756799337	0.696136720738992	NNMT/OAZ2	2
GO:0043687	post-translational protein modification	2/988	37/18722	0.588413756799337	0.696136720738992	TTL/CRTAP	2
GO:0051954	positive regulation of amine transport	2/988	37/18722	0.588413756799337	0.696136720738992	ITGB1/SLC12A2	2
GO:0071542	dopaminergic neuron differentiation	2/988	37/18722	0.588413756799337	0.696136720738992	LRP6/HIF1A	2
GO:0097484	dendrite extension	2/988	37/18722	0.588413756799337	0.696136720738992	ITSN2/SPAG9	2
GO:1905332	positive regulation of morphogenesis of an epithelium	2/988	37/18722	0.588413756799337	0.696136720738992	MDK/GJA1	2
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	5/988	98/18722	0.594993905912651	0.703398434869577	CLU/HIF1A/TMBIM6/CD44/HSPA1A	5
GO:0034637	cellular carbohydrate biosynthetic process	4/988	78/18722	0.595081431909616	0.703398434869577	IGF1/IGF2/GBE1/B4GALT5	4
GO:1901616	organic hydroxy compound catabolic process	4/988	78/18722	0.595081431909616	0.703398434869577	SCARF1/SCARB1/NUDT3/PTEN	4
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	4/988	78/18722	0.595081431909616	0.703398434869577	CD34/IGF1/SYT11/DICER1	4
GO:0032481	positive regulation of type I interferon production	3/988	58/18722	0.59696158612313	0.703440942016132	OAS2/ISG15/G3BP1	3
GO:0044380	protein localization to cytoskeleton	3/988	58/18722	0.59696158612313	0.703440942016132	BICD1/PCM1/APC	3
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	3/988	58/18722	0.59696158612313	0.703440942016132	CAV1/SKIL/SERINC3	3
GO:0000097	sulfur amino acid biosynthetic process	1/988	17/18722	0.602305112445596	0.703440942016132	MRI1	1
GO:0001675	acrosome assembly	1/988	17/18722	0.602305112445596	0.703440942016132	MFSD14A	1
GO:0001829	trophectodermal cell differentiation	1/988	17/18722	0.602305112445596	0.703440942016132	CNOT2	1
GO:0006390	mitochondrial transcription	1/988	17/18722	0.602305112445596	0.703440942016132	PRKAA1	1
GO:0006577	amino-acid betaine metabolic process	1/988	17/18722	0.602305112445596	0.703440942016132	CPT1A	1
GO:0007096	regulation of exit from mitosis	1/988	17/18722	0.602305112445596	0.703440942016132	RGCC	1
GO:0007351	tripartite regional subdivision	1/988	17/18722	0.602305112445596	0.703440942016132	TBX3	1
GO:0007379	segment specification	1/988	17/18722	0.602305112445596	0.703440942016132	MEOX2	1
GO:0008334	histone mRNA metabolic process	1/988	17/18722	0.602305112445596	0.703440942016132	XRN1	1
GO:0008340	determination of adult lifespan	1/988	17/18722	0.602305112445596	0.703440942016132	ZMPSTE24	1
GO:0008595	anterior/posterior axis specification, embryo	1/988	17/18722	0.602305112445596	0.703440942016132	TBX3	1
GO:0009084	glutamine family amino acid biosynthetic process	1/988	17/18722	0.602305112445596	0.703440942016132	GLS	1
GO:0009251	glucan catabolic process	1/988	17/18722	0.602305112445596	0.703440942016132	RB1CC1	1
GO:0010224	response to UV-B	1/988	17/18722	0.602305112445596	0.703440942016132	HYAL2	1
GO:0010470	regulation of gastrulation	1/988	17/18722	0.602305112445596	0.703440942016132	PHLDB2	1
GO:0010566	regulation of ketone biosynthetic process	1/988	17/18722	0.602305112445596	0.703440942016132	EGR1	1
GO:0015867	ATP transport	1/988	17/18722	0.602305112445596	0.703440942016132	GJA1	1
GO:0030903	notochord development	1/988	17/18722	0.602305112445596	0.703440942016132	ID3	1
GO:0031445	regulation of heterochromatin assembly	1/988	17/18722	0.602305112445596	0.703440942016132	ATF7IP	1
GO:0031573	mitotic intra-S DNA damage checkpoint signaling	1/988	17/18722	0.602305112445596	0.703440942016132	ATF2	1
GO:0035269	protein O-linked mannosylation	1/988	17/18722	0.602305112445596	0.703440942016132	TMTC3	1
GO:0036035	osteoclast development	1/988	17/18722	0.602305112445596	0.703440942016132	FOXP1	1
GO:0036065	fucosylation	1/988	17/18722	0.602305112445596	0.703440942016132	FUT11	1
GO:0036166	phenotypic switching	1/988	17/18722	0.602305112445596	0.703440942016132	PDGFB	1
GO:0042339	keratan sulfate metabolic process	1/988	17/18722	0.602305112445596	0.703440942016132	GNS	1
GO:0042448	progesterone metabolic process	1/988	17/18722	0.602305112445596	0.703440942016132	EGR1	1
GO:0043950	positive regulation of cAMP-mediated signaling	1/988	17/18722	0.602305112445596	0.703440942016132	RAPGEF2	1
GO:0045591	positive regulation of regulatory T cell differentiation	1/988	17/18722	0.602305112445596	0.703440942016132	CD46	1
GO:0046068	cGMP metabolic process	1/988	17/18722	0.602305112445596	0.703440942016132	NPR1	1
GO:0046827	positive regulation of protein export from nucleus	1/988	17/18722	0.602305112445596	0.703440942016132	CTDSPL2	1
GO:0046855	inositol phosphate dephosphorylation	1/988	17/18722	0.602305112445596	0.703440942016132	PTEN	1
GO:0048243	norepinephrine secretion	1/988	17/18722	0.602305112445596	0.703440942016132	P2RY1	1
GO:0051580	regulation of neurotransmitter uptake	1/988	17/18722	0.602305112445596	0.703440942016132	ITGB1	1
GO:0051797	regulation of hair follicle development	1/988	17/18722	0.602305112445596	0.703440942016132	SMAD4	1
GO:0055064	chloride ion homeostasis	1/988	17/18722	0.602305112445596	0.703440942016132	SLC12A2	1
GO:0055083	monovalent inorganic anion homeostasis	1/988	17/18722	0.602305112445596	0.703440942016132	SLC12A2	1
GO:0060033	anatomical structure regression	1/988	17/18722	0.602305112445596	0.703440942016132	SMAD5	1
GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	1/988	17/18722	0.602305112445596	0.703440942016132	SESTD1	1
GO:0061952	midbody abscission	1/988	17/18722	0.602305112445596	0.703440942016132	PDCD6IP	1
GO:0071371	cellular response to gonadotropin stimulus	1/988	17/18722	0.602305112445596	0.703440942016132	NOTCH1	1
GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	1/988	17/18722	0.602305112445596	0.703440942016132	DLGAP4	1
GO:0120261	regulation of heterochromatin organization	1/988	17/18722	0.602305112445596	0.703440942016132	ATF7IP	1
GO:1900034	regulation of cellular response to heat	1/988	17/18722	0.602305112445596	0.703440942016132	CD34	1
GO:1900363	regulation of mRNA polyadenylation	1/988	17/18722	0.602305112445596	0.703440942016132	CCNT1	1
GO:1901569	fatty acid derivative catabolic process	1/988	17/18722	0.602305112445596	0.703440942016132	ACAT1	1
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	1/988	17/18722	0.602305112445596	0.703440942016132	WWTR1	1
GO:0006882	cellular zinc ion homeostasis	2/988	38/18722	0.603062885907655	0.703440942016132	SLC30A1/SLC30A7	2
GO:0007094	mitotic spindle assembly checkpoint signaling	2/988	38/18722	0.603062885907655	0.703440942016132	DUSP1/APC	2
GO:0008210	estrogen metabolic process	2/988	38/18722	0.603062885907655	0.703440942016132	HSD17B2/HSD17B12	2
GO:0009309	amine biosynthetic process	2/988	38/18722	0.603062885907655	0.703440942016132	NNMT/OAZ2	2
GO:0032373	positive regulation of sterol transport	2/988	38/18722	0.603062885907655	0.703440942016132	CAV1/ABCA1	2
GO:0032376	positive regulation of cholesterol transport	2/988	38/18722	0.603062885907655	0.703440942016132	CAV1/ABCA1	2
GO:0032717	negative regulation of interleukin-8 production	2/988	38/18722	0.603062885907655	0.703440942016132	TMSB4X/KLF4	2
GO:0032941	secretion by tissue	2/988	38/18722	0.603062885907655	0.703440942016132	PRKCE/WNK1	2
GO:0071173	spindle assembly checkpoint signaling	2/988	38/18722	0.603062885907655	0.703440942016132	DUSP1/APC	2
GO:0071174	mitotic spindle checkpoint signaling	2/988	38/18722	0.603062885907655	0.703440942016132	DUSP1/APC	2
GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	2/988	38/18722	0.603062885907655	0.703440942016132	ATF2/HSPA1A	2
GO:0046034	ATP metabolic process	14/988	277/18722	0.604975198908484	0.705516631526205	IGF1/ZBTB20/COX7A1/TMSB4X/GIT1/APP/TGFB1/RHOA/HIF1A/OGT/STAT3/ATP6V1A/PRKAA1/HSPA1A	14
GO:0006446	regulation of translational initiation	4/988	79/18722	0.605216517562147	0.705643139001344	EIF4G3/EIF2AK2/CSDE1/EIF4G2	4
GO:0051259	protein complex oligomerization	12/988	238/18722	0.606366355962196	0.706828633502564	LRRC8C/KCTD12/B2M/ATL3/GLS/ISG15/PKD2/TNFAIP1/EHD4/PDCD6IP/RNF213/BCL10	12
GO:0051055	negative regulation of lipid biosynthetic process	3/988	59/18722	0.608645693612233	0.70932995271351	CEACAM1/PDGFB/PRKAA1	3
GO:0072655	establishment of protein localization to mitochondrion	6/988	120/18722	0.612275828498265	0.713361794598014	ABLIM3/CALM1/LEPROT/PRKAA1/RALA/SH3GLB1	6
GO:0007292	female gamete generation	7/988	140/18722	0.612373829700103	0.713361794598014	IGF1/RPS6KA2/MDK/CDC25B/PRKAR1A/ZMIZ1/SOS1	7
GO:0006641	triglyceride metabolic process	5/988	100/18722	0.613017293427471	0.713798303964649	CAV1/SCARB1/CPT1A/LPGAT1/SEL1L	5
GO:0046545	development of primary female sexual characteristics	5/988	100/18722	0.613017293427471	0.713798303964649	DACH1/FZD4/NR2F2/CTNNA1/SMAD4	5
GO:0016233	telomere capping	2/988	39/18722	0.617313973562425	0.717857230202189	NEK7/MAPK1	2
GO:0031507	heterochromatin assembly	2/988	39/18722	0.617313973562425	0.717857230202189	ATF7IP/BAZ2A	2
GO:0031577	spindle checkpoint signaling	2/988	39/18722	0.617313973562425	0.717857230202189	DUSP1/APC	2
GO:0032728	positive regulation of interferon-beta production	2/988	39/18722	0.617313973562425	0.717857230202189	OAS2/ISG15	2
GO:0045622	regulation of T-helper cell differentiation	2/988	39/18722	0.617313973562425	0.717857230202189	HLX/RC3H1	2
GO:0051154	negative regulation of striated muscle cell differentiation	2/988	39/18722	0.617313973562425	0.717857230202189	NOTCH1/SMAD4	2
GO:0008202	steroid metabolic process	16/988	319/18722	0.619458595778539	0.718539526870034	HSD17B2/LEPR/SCARF1/SCARB1/IGFBP7/APP/HSD17B12/ACAT1/EGR1/ABCA1/LBR/LIPA/STARD4/PRKAA1/CYB5R3/NFE2L1	16
GO:0031638	zymogen activation	3/988	60/18722	0.620101465920281	0.718539526870034	CLEC3B/THBS1/IFI16	3
GO:0048706	embryonic skeletal system development	6/988	121/18722	0.620367847188022	0.718539526870034	PCSK5/TGFBR2/PCGF2/SULF2/SMAD2/NIPBL	6
GO:0050830	defense response to Gram-positive bacterium	5/988	101/18722	0.621851223136644	0.718539526870034	GBP4/HLA-E/HLA-A/TNFRSF14/CD36	5
GO:0051963	regulation of synapse assembly	5/988	101/18722	0.621851223136644	0.718539526870034	ADGRL2/MEF2C/AGRN/PDLIM5/APP	5
GO:0098869	cellular oxidant detoxification	5/988	101/18722	0.621851223136644	0.718539526870034	NXN/CLIC2/MGST2/TP53INP1/CD36	5
GO:0002295	T-helper cell lineage commitment	1/988	18/18722	0.623311396802921	0.718539526870034	STAT3	1
GO:0002501	peptide antigen assembly with MHC protein complex	1/988	18/18722	0.623311396802921	0.718539526870034	B2M	1
GO:0003128	heart field specification	1/988	18/18722	0.623311396802921	0.718539526870034	MEF2C	1
GO:0006337	nucleosome disassembly	1/988	18/18722	0.623311396802921	0.718539526870034	ARID1A	1
GO:0009125	nucleoside monophosphate catabolic process	1/988	18/18722	0.623311396802921	0.718539526870034	NT5E	1
GO:0009404	toxin metabolic process	1/988	18/18722	0.623311396802921	0.718539526870034	PAM	1
GO:0015936	coenzyme A metabolic process	1/988	18/18722	0.623311396802921	0.718539526870034	ACAT1	1
GO:0019184	nonribosomal peptide biosynthetic process	1/988	18/18722	0.623311396802921	0.718539526870034	MGST2	1
GO:0030206	chondroitin sulfate biosynthetic process	1/988	18/18722	0.623311396802921	0.718539526870034	CHSY1	1
GO:0030299	intestinal cholesterol absorption	1/988	18/18722	0.623311396802921	0.718539526870034	CD36	1
GO:0031000	response to caffeine	1/988	18/18722	0.623311396802921	0.718539526870034	PRKAA1	1
GO:0031649	heat generation	1/988	18/18722	0.623311396802921	0.718539526870034	ADRB1	1
GO:0032305	positive regulation of icosanoid secretion	1/988	18/18722	0.623311396802921	0.718539526870034	EDN1	1
GO:0032634	interleukin-5 production	1/988	18/18722	0.623311396802921	0.718539526870034	PDE4D	1
GO:0032674	regulation of interleukin-5 production	1/988	18/18722	0.623311396802921	0.718539526870034	PDE4D	1
GO:0034134	toll-like receptor 2 signaling pathway	1/988	18/18722	0.623311396802921	0.718539526870034	PJA2	1
GO:0034162	toll-like receptor 9 signaling pathway	1/988	18/18722	0.623311396802921	0.718539526870034	RTN4	1
GO:0044247	cellular polysaccharide catabolic process	1/988	18/18722	0.623311396802921	0.718539526870034	RB1CC1	1
GO:0045187	regulation of circadian sleep/wake cycle, sleep	1/988	18/18722	0.623311396802921	0.718539526870034	ADRB1	1
GO:0045653	negative regulation of megakaryocyte differentiation	1/988	18/18722	0.623311396802921	0.718539526870034	GABPA	1
GO:0046838	phosphorylated carbohydrate dephosphorylation	1/988	18/18722	0.623311396802921	0.718539526870034	PTEN	1
GO:0051782	negative regulation of cell division	1/988	18/18722	0.623311396802921	0.718539526870034	TXNIP	1
GO:0060192	negative regulation of lipase activity	1/988	18/18722	0.623311396802921	0.718539526870034	BICD1	1
GO:0060457	negative regulation of digestive system process	1/988	18/18722	0.623311396802921	0.718539526870034	WNK1	1
GO:0060546	negative regulation of necroptotic process	1/988	18/18722	0.623311396802921	0.718539526870034	CAV1	1
GO:0061687	detoxification of inorganic compound	1/988	18/18722	0.623311396802921	0.718539526870034	SLC30A1	1
GO:0097094	craniofacial suture morphogenesis	1/988	18/18722	0.623311396802921	0.718539526870034	FOXN3	1
GO:0097107	postsynaptic density assembly	1/988	18/18722	0.623311396802921	0.718539526870034	PTEN	1
GO:0099558	maintenance of synapse structure	1/988	18/18722	0.623311396802921	0.718539526870034	CTBP2	1
GO:0150078	positive regulation of neuroinflammatory response	1/988	18/18722	0.623311396802921	0.718539526870034	IL33	1
GO:1900006	positive regulation of dendrite development	1/988	18/18722	0.623311396802921	0.718539526870034	IQGAP1	1
GO:1901673	regulation of mitotic spindle assembly	1/988	18/18722	0.623311396802921	0.718539526870034	HSPA1A	1
GO:1902074	response to salt	1/988	18/18722	0.623311396802921	0.718539526870034	EDN1	1
GO:2001135	regulation of endocytic recycling	1/988	18/18722	0.623311396802921	0.718539526870034	EHD2	1
GO:0000422	autophagy of mitochondrion	4/988	81/18722	0.625016247636057	0.719723890622748	HIF1A/RB1CC1/CTTN/VPS13C	4
GO:0008589	regulation of smoothened signaling pathway	4/988	81/18722	0.625016247636057	0.719723890622748	RB1/CHSY1/CTNNA1/WDR11	4
GO:0010833	telomere maintenance via telomere lengthening	4/988	81/18722	0.625016247636057	0.719723890622748	HMBOX1/NEK7/MAPK1/XRN1	4
GO:0061726	mitochondrion disassembly	4/988	81/18722	0.625016247636057	0.719723890622748	HIF1A/RB1CC1/CTTN/VPS13C	4
GO:2000243	positive regulation of reproductive process	4/988	81/18722	0.625016247636057	0.719723890622748	P2RY1/PLCB1/SMURF2/CDC25B	4
GO:0062014	negative regulation of small molecule metabolic process	5/988	102/18722	0.630563866091721	0.725261199712676	LEPR/CEACAM1/GIT1/STAT3/ATP2B4	5
GO:0010863	positive regulation of phospholipase C activity	2/988	40/18722	0.631168192893299	0.725261199712676	FGFR1/GNAQ	2
GO:0031297	replication fork processing	2/988	40/18722	0.631168192893299	0.725261199712676	ATRX/FAM111A	2
GO:0032094	response to food	2/988	40/18722	0.631168192893299	0.725261199712676	PLEC/BCL10	2
GO:0044275	cellular carbohydrate catabolic process	2/988	40/18722	0.631168192893299	0.725261199712676	SCARB2/RB1CC1	2
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2/988	40/18722	0.631168192893299	0.725261199712676	DUSP1/APC	2
GO:0055069	zinc ion homeostasis	2/988	40/18722	0.631168192893299	0.725261199712676	SLC30A1/SLC30A7	2
GO:0071276	cellular response to cadmium ion	2/988	40/18722	0.631168192893299	0.725261199712676	MAPK1/JUN	2
GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	2/988	40/18722	0.631168192893299	0.725261199712676	ATF2/HSPA1A	2
GO:0043966	histone H3 acetylation	3/988	61/18722	0.631326767219769	0.725261199712676	KMT2A/KAT6A/SMAD4	3
GO:1905515	non-motile cilium assembly	3/988	61/18722	0.631326767219769	0.725261199712676	EXOC5/PCM1/MAP4	3
GO:0006865	amino acid transport	7/988	143/18722	0.63465505483957	0.728927059742226	LRRC8C/SLC38A2/ITGB1/SERINC3/SLC12A2/GJA1/SLC16A2	7
GO:0071482	cellular response to light stimulus	6/988	123/18722	0.636259767184977	0.73061216672862	HYAL2/TIMP1/CARD16/TP53INP1/POLK/NEDD4	6
GO:0007018	microtubule-based movement	19/988	382/18722	0.638623076815522	0.733045960485777	BICD1/DST/KIF5B/APP/KTN1/ARMCX3/LAMP1/ACTR2/SUN1/HIF1A/PURA/PCM1/KIF1B/ATP2B4/ASH1L/MAP4/DYNC1H1/CDC42/KIFAP3	19
GO:0090277	positive regulation of peptide hormone secretion	5/988	103/18722	0.6391533891783	0.733045960485777	NNAT/PRKCE/KIF5B/GJA1/HIF1A	5
GO:0060113	inner ear receptor cell differentiation	3/988	62/18722	0.64231998698832	0.733045960485777	JAG1/NOTCH1/HES1	3
GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	1/988	19/18722	0.643209190855461	0.733045960485777	CNOT8	1
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	1/988	19/18722	0.643209190855461	0.733045960485777	HLA-E	1
GO:0006309	apoptotic DNA fragmentation	1/988	19/18722	0.643209190855461	0.733045960485777	DICER1	1
GO:0007039	protein catabolic process in the vacuole	1/988	19/18722	0.643209190855461	0.733045960485777	CD81	1
GO:0007603	phototransduction, visible light	1/988	19/18722	0.643209190855461	0.733045960485777	GNAQ	1
GO:0008356	asymmetric cell division	1/988	19/18722	0.643209190855461	0.733045960485777	ACTR2	1
GO:0009081	branched-chain amino acid metabolic process	1/988	19/18722	0.643209190855461	0.733045960485777	ACAT1	1
GO:0010002	cardioblast differentiation	1/988	19/18722	0.643209190855461	0.733045960485777	NOTCH1	1
GO:0016082	synaptic vesicle priming	1/988	19/18722	0.643209190855461	0.733045960485777	SNAP23	1
GO:0032616	interleukin-13 production	1/988	19/18722	0.643209190855461	0.733045960485777	HLA-E	1
GO:0032656	regulation of interleukin-13 production	1/988	19/18722	0.643209190855461	0.733045960485777	HLA-E	1
GO:0032695	negative regulation of interleukin-12 production	1/988	19/18722	0.643209190855461	0.733045960485777	THBS1	1
GO:0035461	vitamin transmembrane transport	1/988	19/18722	0.643209190855461	0.733045960485777	SCARB1	1
GO:0038092	nodal signaling pathway	1/988	19/18722	0.643209190855461	0.733045960485777	SMAD2	1
GO:0043652	engulfment of apoptotic cell	1/988	19/18722	0.643209190855461	0.733045960485777	THBS1	1
GO:0044003	modulation by symbiont of host process	1/988	19/18722	0.643209190855461	0.733045960485777	HYAL2	1
GO:0045780	positive regulation of bone resorption	1/988	19/18722	0.643209190855461	0.733045960485777	LTBP3	1
GO:0046033	AMP metabolic process	1/988	19/18722	0.643209190855461	0.733045960485777	NT5E	1
GO:0046716	muscle cell cellular homeostasis	1/988	19/18722	0.643209190855461	0.733045960485777	HIF1A	1
GO:0051444	negative regulation of ubiquitin-protein transferase activity	1/988	19/18722	0.643209190855461	0.733045960485777	DTX3L	1
GO:0061760	antifungal innate immune response	1/988	19/18722	0.643209190855461	0.733045960485777	BCL10	1
GO:0062099	negative regulation of programmed necrotic cell death	1/988	19/18722	0.643209190855461	0.733045960485777	CAV1	1
GO:0070233	negative regulation of T cell apoptotic process	1/988	19/18722	0.643209190855461	0.733045960485777	HIF1A	1
GO:0070734	histone H3-K27 methylation	1/988	19/18722	0.643209190855461	0.733045960485777	OGT	1
GO:0097501	stress response to metal ion	1/988	19/18722	0.643209190855461	0.733045960485777	SLC30A1	1
GO:0098780	response to mitochondrial depolarisation	1/988	19/18722	0.643209190855461	0.733045960485777	VPS13C	1
GO:1901659	glycosyl compound biosynthetic process	1/988	19/18722	0.643209190855461	0.733045960485777	NT5E	1
GO:1901881	positive regulation of protein depolymerization	1/988	19/18722	0.643209190855461	0.733045960485777	DSTN	1
GO:1903978	regulation of microglial cell activation	1/988	19/18722	0.643209190855461	0.733045960485777	SYT11	1
GO:2000042	negative regulation of double-strand break repair via homologous recombination	1/988	19/18722	0.643209190855461	0.733045960485777	RIF1	1
GO:2000269	regulation of fibroblast apoptotic process	1/988	19/18722	0.643209190855461	0.733045960485777	PIK3CA	1
GO:2000319	regulation of T-helper 17 cell differentiation	1/988	19/18722	0.643209190855461	0.733045960485777	RC3H1	1
GO:0043367	CD4-positive, alpha-beta T cell differentiation	4/988	83/18722	0.644173791517537	0.73398781221389	HLX/FOXP1/STAT3/RC3H1	4
GO:0050691	regulation of defense response to virus by host	2/988	41/18722	0.644627700895196	0.734347490275634	PARP9/DTX3L	2
GO:0022412	cellular process involved in reproduction in multicellular organism	19/988	384/18722	0.647593852757373	0.737437861969432	JAM2/IGF1/FZD4/RPS6KA2/ANGPT2/ITGB1/SMAD5/MDK/JAM3/CDC25B/PRKAR1A/FNDC3A/QKI/MFSD14A/CELF1/ZMIZ1/CD9/DDX6/SOS1	19
GO:0022600	digestive system process	5/988	104/18722	0.647618152501393	0.737437861969432	SCARB1/UGCG/CD36/F11R/WNK1	5
GO:0046902	regulation of mitochondrial membrane permeability	3/988	63/18722	0.653080008320374	0.743497857736354	STAT3/ATF2/HSPA1A	3
GO:0006835	dicarboxylic acid transport	4/988	84/18722	0.653507280494336	0.743824871220465	LRRC8C/ITGB1/SLC12A2/GJA1	4
GO:0019432	triglyceride biosynthetic process	2/988	42/18722	0.657695531522352	0.746835087610517	SCARB1/LPGAT1	2
GO:0021575	hindbrain morphogenesis	2/988	42/18722	0.657695531522352	0.746835087610517	DLC1/HES1	2
GO:0030574	collagen catabolic process	2/988	42/18722	0.657695531522352	0.746835087610517	ADAM15/ITGB1	2
GO:0051452	intracellular pH reduction	2/988	42/18722	0.657695531522352	0.746835087610517	CLIC4/CLCN3	2
GO:0051602	response to electrical stimulus	2/988	42/18722	0.657695531522352	0.746835087610517	PTEN/BTG2	2
GO:0060999	positive regulation of dendritic spine development	2/988	42/18722	0.657695531522352	0.746835087610517	ACTR2/EIF4G2	2
GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	2/988	42/18722	0.657695531522352	0.746835087610517	DUSP1/APC	2
GO:0000272	polysaccharide catabolic process	1/988	20/18722	0.662056932898706	0.746835087610517	RB1CC1	1
GO:0001832	blastocyst growth	1/988	20/18722	0.662056932898706	0.746835087610517	IGF1	1
GO:0006346	DNA methylation-dependent heterochromatin assembly	1/988	20/18722	0.662056932898706	0.746835087610517	ATF7IP	1
GO:0006700	C21-steroid hormone biosynthetic process	1/988	20/18722	0.662056932898706	0.746835087610517	EGR1	1
GO:0006883	cellular sodium ion homeostasis	1/988	20/18722	0.662056932898706	0.746835087610517	SLC12A2	1
GO:0006896	Golgi to vacuole transport	1/988	20/18722	0.662056932898706	0.746835087610517	LAMP1	1
GO:0007194	negative regulation of adenylate cyclase activity	1/988	20/18722	0.662056932898706	0.746835087610517	GNAI2	1
GO:0007620	copulation	1/988	20/18722	0.662056932898706	0.746835087610517	P2RY1	1
GO:0010042	response to manganese ion	1/988	20/18722	0.662056932898706	0.746835087610517	APP	1
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	1/988	20/18722	0.662056932898706	0.746835087610517	CALM1	1
GO:0014047	glutamate secretion	1/988	20/18722	0.662056932898706	0.746835087610517	GJA1	1
GO:0016553	base conversion or substitution editing	1/988	20/18722	0.662056932898706	0.746835087610517	ADAR	1
GO:0031498	chromatin disassembly	1/988	20/18722	0.662056932898706	0.746835087610517	ARID1A	1
GO:0032211	negative regulation of telomere maintenance via telomerase	1/988	20/18722	0.662056932898706	0.746835087610517	XRN1	1
GO:0032793	positive regulation of CREB transcription factor activity	1/988	20/18722	0.662056932898706	0.746835087610517	CD200	1
GO:0032986	protein-DNA complex disassembly	1/988	20/18722	0.662056932898706	0.746835087610517	ARID1A	1
GO:0033005	positive regulation of mast cell activation	1/988	20/18722	0.662056932898706	0.746835087610517	GATA2	1
GO:0043011	myeloid dendritic cell differentiation	1/988	20/18722	0.662056932898706	0.746835087610517	TGFBR2	1
GO:0043651	linoleic acid metabolic process	1/988	20/18722	0.662056932898706	0.746835087610517	ELOVL5	1
GO:0045063	T-helper 1 cell differentiation	1/988	20/18722	0.662056932898706	0.746835087610517	HLX	1
GO:0051004	regulation of lipoprotein lipase activity	1/988	20/18722	0.662056932898706	0.746835087610517	PCSK5	1
GO:0051900	regulation of mitochondrial depolarization	1/988	20/18722	0.662056932898706	0.746835087610517	KDR	1
GO:0052695	cellular glucuronidation	1/988	20/18722	0.662056932898706	0.746835087610517	PRKCE	1
GO:0060231	mesenchymal to epithelial transition	1/988	20/18722	0.662056932898706	0.746835087610517	TCF15	1
GO:0060252	positive regulation of glial cell proliferation	1/988	20/18722	0.662056932898706	0.746835087610517	PRKCH	1
GO:0061003	positive regulation of dendritic spine morphogenesis	1/988	20/18722	0.662056932898706	0.746835087610517	ACTR2	1
GO:0070166	enamel mineralization	1/988	20/18722	0.662056932898706	0.746835087610517	FOXO1	1
GO:0071243	cellular response to arsenic-containing substance	1/988	20/18722	0.662056932898706	0.746835087610517	SLC38A2	1
GO:1901386	negative regulation of voltage-gated calcium channel activity	1/988	20/18722	0.662056932898706	0.746835087610517	CALM1	1
GO:1901679	nucleotide transmembrane transport	1/988	20/18722	0.662056932898706	0.746835087610517	LRRC8C	1
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	1/988	20/18722	0.662056932898706	0.746835087610517	HIF1A	1
GO:1903817	negative regulation of voltage-gated potassium channel activity	1/988	20/18722	0.662056932898706	0.746835087610517	CAV1	1
GO:1904263	positive regulation of TORC1 signaling	1/988	20/18722	0.662056932898706	0.746835087610517	WAC	1
GO:2000010	positive regulation of protein localization to cell surface	1/988	20/18722	0.662056932898706	0.746835087610517	STX3	1
GO:2000678	negative regulation of transcription regulatory region DNA binding	1/988	20/18722	0.662056932898706	0.746835087610517	TMSB4X	1
GO:0009142	nucleoside triphosphate biosynthetic process	4/988	85/18722	0.662675438743511	0.747374082931111	TMSB4X/TGFB1/STAT3/ATP6V1A	4
GO:0006749	glutathione metabolic process	3/988	64/18722	0.663606177182261	0.747947382387475	CLIC2/MGST2/GLO1	3
GO:0016126	sterol biosynthetic process	3/988	64/18722	0.663606177182261	0.747947382387475	LBR/PRKAA1/CYB5R3	3
GO:0046530	photoreceptor cell differentiation	3/988	64/18722	0.663606177182261	0.747947382387475	NOTCH1/TUG1/STAT3	3
GO:0002793	positive regulation of peptide secretion	5/988	106/18722	0.664167771860005	0.748421553695449	NNAT/PRKCE/KIF5B/GJA1/HIF1A	5
GO:0044782	cilium organization	18/988	368/18722	0.664477807623459	0.748612113275889	ABLIM1/ABLIM3/EHD2/WWTR1/NOTCH1/EXOC5/FLNA/ACTR2/CYLD/PCM1/PKD2/EHD4/CCDC88A/GSN/WDR11/MAP4/TTC17/KIFAP3	18
GO:0048839	inner ear development	9/988	188/18722	0.66531536529882	0.749396781269578	SPARC/HOXA13/DCHS1/JAG1/NOTCH1/ADAM10/GATA2/FZD6/HES1	9
GO:0009268	response to pH	2/988	43/18722	0.670375497306692	0.752861446446754	PAM/GJA1	2
GO:0016266	O-glycan processing	2/988	43/18722	0.670375497306692	0.752861446446754	ST6GAL1/B4GALT5	2
GO:0033046	negative regulation of sister chromatid segregation	2/988	43/18722	0.670375497306692	0.752861446446754	DUSP1/APC	2
GO:0033048	negative regulation of mitotic sister chromatid segregation	2/988	43/18722	0.670375497306692	0.752861446446754	DUSP1/APC	2
GO:0034142	toll-like receptor 4 signaling pathway	2/988	43/18722	0.670375497306692	0.752861446446754	PRKCE/WDFY1	2
GO:0034661	ncRNA catabolic process	2/988	43/18722	0.670375497306692	0.752861446446754	DICER1/XRN1	2
GO:0035794	positive regulation of mitochondrial membrane permeability	2/988	43/18722	0.670375497306692	0.752861446446754	ATF2/HSPA1A	2
GO:0036230	granulocyte activation	2/988	43/18722	0.670375497306692	0.752861446446754	FCGR2B/KMT2E	2
GO:0042088	T-helper 1 type immune response	2/988	43/18722	0.670375497306692	0.752861446446754	HLX/IL1R1	2
GO:0045494	photoreceptor cell maintenance	2/988	43/18722	0.670375497306692	0.752861446446754	SLC2A1/CLCN3	2
GO:0098815	modulation of excitatory postsynaptic potential	2/988	43/18722	0.670375497306692	0.752861446446754	APP/PTEN	2
GO:0140353	lipid export from cell	2/988	43/18722	0.670375497306692	0.752861446446754	EDN1/FZD4	2
GO:1901381	positive regulation of potassium ion transmembrane transport	2/988	43/18722	0.670375497306692	0.752861446446754	FLNA/WNK1	2
GO:2000816	negative regulation of mitotic sister chromatid separation	2/988	43/18722	0.670375497306692	0.752861446446754	DUSP1/APC	2
GO:2001251	negative regulation of chromosome organization	4/988	86/18722	0.671677245596178	0.754163924879919	DUSP1/ATRX/APC/XRN1	4
GO:0045453	bone resorption	3/988	65/18722	0.67389827264849	0.75617820538842	S1PR1/PDK4/LTBP3	3
GO:0051310	metaphase plate congression	3/988	65/18722	0.67389827264849	0.75617820538842	TTL/RAB11A/DYNC1H1	3
GO:1905330	regulation of morphogenesis of an epithelium	3/988	65/18722	0.67389827264849	0.75617820538842	FOXP1/MDK/GJA1	3
GO:0006639	acylglycerol metabolic process	6/988	128/18722	0.674217647223812	0.756376798744011	CAV1/SCARB1/DGKH/CPT1A/LPGAT1/SEL1L	6
GO:0006091	generation of precursor metabolites and energy	24/988	490/18722	0.677341662105252	0.756690096746265	IGF1/ADGRF5/KL/LEPR/IDO1/ZBTB20/LOXL2/PCDH12/COX7A1/IGF2/GIT1/APP/IL6ST/PIK3CA/RHOA/HIF1A/OGT/STAT3/IFNAR1/ACAT1/RB1CC1/PRKAA1/PLEC/GBE1	24
GO:0009566	fertilization	9/988	190/18722	0.67750661290767	0.756690096746265	PLCB1/MYH9/FNDC3A/NR2F2/CLIC4/ASH1L/CD9/CD46/SMAD4	9
GO:0006302	double-strand break repair	12/988	251/18722	0.678737462699747	0.756690096746265	REV3L/PML/SLF2/SETX/ACTR2/RECQL/PARP9/NIPBL/DTX3L/TRIP12/KMT5B/RIF1	12
GO:0002689	negative regulation of leukocyte chemotaxis	1/988	21/18722	0.679909983390422	0.756690096746265	DUSP1	1
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	1/988	21/18722	0.679909983390422	0.756690096746265	COX7A1	1
GO:0007289	spermatid nucleus differentiation	1/988	21/18722	0.679909983390422	0.756690096746265	MFSD14A	1
GO:0009070	serine family amino acid biosynthetic process	1/988	21/18722	0.679909983390422	0.756690096746265	SERINC3	1
GO:0010988	regulation of low-density lipoprotein particle clearance	1/988	21/18722	0.679909983390422	0.756690096746265	HNRNPK	1
GO:0016075	rRNA catabolic process	1/988	21/18722	0.679909983390422	0.756690096746265	XRN1	1
GO:0019370	leukotriene biosynthetic process	1/988	21/18722	0.679909983390422	0.756690096746265	MGST2	1
GO:0021533	cell differentiation in hindbrain	1/988	21/18722	0.679909983390422	0.756690096746265	GATA2	1
GO:0031145	anaphase-promoting complex-dependent catabolic process	1/988	21/18722	0.679909983390422	0.756690096746265	CDC27	1
GO:0031998	regulation of fatty acid beta-oxidation	1/988	21/18722	0.679909983390422	0.756690096746265	CPT1A	1
GO:0032303	regulation of icosanoid secretion	1/988	21/18722	0.679909983390422	0.756690096746265	EDN1	1
GO:0032482	Rab protein signal transduction	1/988	21/18722	0.679909983390422	0.756690096746265	GDI1	1
GO:0033762	response to glucagon	1/988	21/18722	0.679909983390422	0.756690096746265	CREB1	1
GO:0034035	purine ribonucleoside bisphosphate metabolic process	1/988	21/18722	0.679909983390422	0.756690096746265	PAPSS2	1
GO:0034312	diol biosynthetic process	1/988	21/18722	0.679909983390422	0.756690096746265	SPTLC2	1
GO:0039702	viral budding via host ESCRT complex	1/988	21/18722	0.679909983390422	0.756690096746265	PDCD6IP	1
GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	1/988	21/18722	0.679909983390422	0.756690096746265	STAT3	1
GO:0043576	regulation of respiratory gaseous exchange	1/988	21/18722	0.679909983390422	0.756690096746265	GLS	1
GO:0044241	lipid digestion	1/988	21/18722	0.679909983390422	0.756690096746265	CD36	1
GO:0044342	type B pancreatic cell proliferation	1/988	21/18722	0.679909983390422	0.756690096746265	IGFBP4	1
GO:0045717	negative regulation of fatty acid biosynthetic process	1/988	21/18722	0.679909983390422	0.756690096746265	CEACAM1	1
GO:0046128	purine ribonucleoside metabolic process	1/988	21/18722	0.679909983390422	0.756690096746265	NT5E	1
GO:0046599	regulation of centriole replication	1/988	21/18722	0.679909983390422	0.756690096746265	PLK2	1
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	1/988	21/18722	0.679909983390422	0.756690096746265	PAPSS2	1
GO:0050802	circadian sleep/wake cycle, sleep	1/988	21/18722	0.679909983390422	0.756690096746265	ADRB1	1
GO:0060972	left/right pattern formation	1/988	21/18722	0.679909983390422	0.756690096746265	NOTCH1	1
GO:0070584	mitochondrion morphogenesis	1/988	21/18722	0.679909983390422	0.756690096746265	PLEC	1
GO:0090026	positive regulation of monocyte chemotaxis	1/988	21/18722	0.679909983390422	0.756690096746265	MOSPD2	1
GO:0098698	postsynaptic specialization assembly	1/988	21/18722	0.679909983390422	0.756690096746265	PTEN	1
GO:0098719	sodium ion import across plasma membrane	1/988	21/18722	0.679909983390422	0.756690096746265	SLC12A2	1
GO:0150146	cell junction disassembly	1/988	21/18722	0.679909983390422	0.756690096746265	MAP4K4	1
GO:1900118	negative regulation of execution phase of apoptosis	1/988	21/18722	0.679909983390422	0.756690096746265	PAK2	1
GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	1/988	21/18722	0.679909983390422	0.756690096746265	HSPA1A	1
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	1/988	21/18722	0.679909983390422	0.756690096746265	CD44	1
GO:2000774	positive regulation of cellular senescence	1/988	21/18722	0.679909983390422	0.756690096746265	B2M	1
GO:0022037	metencephalon development	5/988	108/18722	0.680203249276096	0.756857909542233	FCGR2B/FZD4/MDK/CRK/ATF2	5
GO:0044070	regulation of anion transport	4/988	87/18722	0.680511934598448	0.757042805567948	EDN1/ITGB1/SLC12A2/PRKAA1	4
GO:0006638	neutral lipid metabolic process	6/988	129/18722	0.681496149149734	0.757978966558498	CAV1/SCARB1/DGKH/CPT1A/LPGAT1/SEL1L	6
GO:0032007	negative regulation of TOR signaling	2/988	44/18722	0.682672098899975	0.758651504049512	HIF1A/PRKAA1	2
GO:0048066	developmental pigmentation	2/988	44/18722	0.682672098899975	0.758651504049512	MEF2C/RAB27A	2
GO:0089718	amino acid import across plasma membrane	2/988	44/18722	0.682672098899975	0.758651504049512	ITGB1/SLC16A2	2
GO:0097178	ruffle assembly	2/988	44/18722	0.682672098899975	0.758651504049512	CAV1/RDX	2
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	3/988	66/18722	0.683956478147893	0.759443313528764	TGFB1/KMT5B/RIF1	3
GO:0016444	somatic cell DNA recombination	3/988	66/18722	0.683956478147893	0.759443313528764	TGFB1/KMT5B/RIF1	3
GO:0032715	negative regulation of interleukin-6 production	3/988	66/18722	0.683956478147893	0.759443313528764	SYT11/KLF2/CD200	3
GO:1902476	chloride transmembrane transport	3/988	66/18722	0.683956478147893	0.759443313528764	CLIC2/SLC12A2/CLCN3	3
GO:0030258	lipid modification	10/988	212/18722	0.687041417089979	0.762709301480035	PLPP1/DGKH/PDK4/CPT1A/PLPP3/PTEN/MTMR6/ACAT1/STARD4/PRKAA1	10
GO:0006821	chloride transport	5/988	109/18722	0.688025971916627	0.763642700129779	CLIC2/TTYH3/SLC12A2/CLIC4/CLCN3	5
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	6/988	130/18722	0.688668220050006	0.7640362541574	BCAP29/YIPF4/ERGIC1/SEC23A/SEC31A/TMED7	6
GO:0006956	complement activation	6/988	130/18722	0.688668220050006	0.7640362541574	A2M/CFI/RGCC/CLU/CD59/CD46	6
GO:0030101	natural killer cell activation	4/988	88/18722	0.689178981575704	0.764283663910258	HLA-E/LAMP1/RAB27A/HECTD1	4
GO:0070098	chemokine-mediated signaling pathway	4/988	88/18722	0.689178981575704	0.764283663910258	EDN1/SH2B3/HIF1A/WNK1	4
GO:0006261	DNA-dependent DNA replication	7/988	151/18722	0.690333969840214	0.765404727153249	DACH1/REV3L/ATRX/PURA/RECQL/FAM111A/ZMPSTE24	7
GO:0006879	cellular iron ion homeostasis	3/988	67/18722	0.693781353740092	0.76763003318259	HIF1A/ATP6V1A/SMAD4	3
GO:0010517	regulation of phospholipase activity	3/988	67/18722	0.693781353740092	0.76763003318259	BICD1/FGFR1/GNAQ	3
GO:0016445	somatic diversification of immunoglobulins	3/988	67/18722	0.693781353740092	0.76763003318259	TGFB1/KMT5B/RIF1	3
GO:0042490	mechanoreceptor differentiation	3/988	67/18722	0.693781353740092	0.76763003318259	JAG1/NOTCH1/HES1	3
GO:0003254	regulation of membrane depolarization	2/988	45/18722	0.694590441978748	0.76763003318259	KDR/GJA5	2
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	2/988	45/18722	0.694590441978748	0.76763003318259	PML/HIF1A	2
GO:0022602	ovulation cycle process	2/988	45/18722	0.694590441978748	0.76763003318259	FZD4/PAM	2
GO:0051985	negative regulation of chromosome segregation	2/988	45/18722	0.694590441978748	0.76763003318259	DUSP1/APC	2
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	2/988	45/18722	0.694590441978748	0.76763003318259	ATF2/HSPA1A	2
GO:1905819	negative regulation of chromosome separation	2/988	45/18722	0.694590441978748	0.76763003318259	DUSP1/APC	2
GO:0009063	cellular amino acid catabolic process	5/988	110/18722	0.695717826517292	0.76763003318259	IDO1/GLS/DDAH2/ACAT1/ATP2B4	5
GO:1905954	positive regulation of lipid localization	5/988	110/18722	0.695717826517292	0.76763003318259	EDN1/CAV1/SCARB1/CD36/ABCA1	5
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	1/988	22/18722	0.696820786898805	0.76763003318259	APLNR	1
GO:0006063	uronic acid metabolic process	1/988	22/18722	0.696820786898805	0.76763003318259	PRKCE	1
GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	1/988	22/18722	0.696820786898805	0.76763003318259	CD9	1
GO:0010866	regulation of triglyceride biosynthetic process	1/988	22/18722	0.696820786898805	0.76763003318259	SCARB1	1
GO:0019585	glucuronate metabolic process	1/988	22/18722	0.696820786898805	0.76763003318259	PRKCE	1
GO:0022401	negative adaptation of signaling pathway	1/988	22/18722	0.696820786898805	0.76763003318259	APLNR	1
GO:0031061	negative regulation of histone methylation	1/988	22/18722	0.696820786898805	0.76763003318259	BCOR	1
GO:0032891	negative regulation of organic acid transport	1/988	22/18722	0.696820786898805	0.76763003318259	THBS1	1
GO:0042430	indole-containing compound metabolic process	1/988	22/18722	0.696820786898805	0.76763003318259	IDO1	1
GO:0042749	regulation of circadian sleep/wake cycle	1/988	22/18722	0.696820786898805	0.76763003318259	ADRB1	1
GO:0044346	fibroblast apoptotic process	1/988	22/18722	0.696820786898805	0.76763003318259	PIK3CA	1
GO:0045048	protein insertion into ER membrane	1/988	22/18722	0.696820786898805	0.76763003318259	TRAM1	1
GO:0045540	regulation of cholesterol biosynthetic process	1/988	22/18722	0.696820786898805	0.76763003318259	PRKAA1	1
GO:0045624	positive regulation of T-helper cell differentiation	1/988	22/18722	0.696820786898805	0.76763003318259	HLX	1
GO:0051151	negative regulation of smooth muscle cell differentiation	1/988	22/18722	0.696820786898805	0.76763003318259	PDGFB	1
GO:0060563	neuroepithelial cell differentiation	1/988	22/18722	0.696820786898805	0.76763003318259	HES1	1
GO:0097164	ammonium ion metabolic process	1/988	22/18722	0.696820786898805	0.76763003318259	SLC44A1	1
GO:0106118	regulation of sterol biosynthetic process	1/988	22/18722	0.696820786898805	0.76763003318259	PRKAA1	1
GO:2000193	positive regulation of fatty acid transport	1/988	22/18722	0.696820786898805	0.76763003318259	EDN1	1
GO:1900407	regulation of cellular response to oxidative stress	4/988	89/18722	0.697678092855574	0.768415100404066	FYN/NCOA7/CD36/HIF1A	4
GO:0009988	cell-cell recognition	3/988	68/18722	0.703373809435492	0.774527710555832	MSN/CD81/CD9	3
GO:0007601	visual perception	10/988	215/18722	0.703673791938122	0.774697447207317	ABLIM1/HMCN1/COL18A1/EPAS1/LAMB2/CRYBG3/EFEMP1/CHM/MYO9A/ATF6	10
GO:0048477	oogenesis	4/988	90/18722	0.706009193673877	0.776442824915967	IGF1/RPS6KA2/MDK/CDC25B	4
GO:0033047	regulation of mitotic sister chromatid segregation	2/988	46/18722	0.706136160988146	0.776442824915967	DUSP1/APC	2
GO:0043462	regulation of ATPase activity	2/988	46/18722	0.706136160988146	0.776442824915967	DNAJC10/CNN3	2
GO:0044818	mitotic G2/M transition checkpoint	2/988	46/18722	0.706136160988146	0.776442824915967	TAOK1/FOXN3	2
GO:0045851	pH reduction	2/988	46/18722	0.706136160988146	0.776442824915967	CLIC4/CLCN3	2
GO:0050919	negative chemotaxis	2/988	46/18722	0.706136160988146	0.776442824915967	RHOA/SEMA3F	2
GO:0015980	energy derivation by oxidation of organic compounds	15/988	318/18722	0.709627217454799	0.779456752502122	IGF1/ADGRF5/KL/LEPR/PCDH12/COX7A1/IGF2/IL6ST/PIK3CA/RHOA/HIF1A/IFNAR1/RB1CC1/PLEC/GBE1	15
GO:0001676	long-chain fatty acid metabolic process	5/988	112/18722	0.710707270634718	0.779456752502122	PAM/CPT1A/ACSL3/ELOVL5/QKI	5
GO:0032609	interferon-gamma production	5/988	112/18722	0.710707270634718	0.779456752502122	PDE4D/IL1R1/HLA-A/PDE4B/ISG15	5
GO:0032649	regulation of interferon-gamma production	5/988	112/18722	0.710707270634718	0.779456752502122	PDE4D/IL1R1/HLA-A/PDE4B/ISG15	5
GO:0006368	transcription elongation from RNA polymerase II promoter	3/988	69/18722	0.712735079565529	0.779456752502122	ZMYND11/ZMIZ1/ARID1A	3
GO:0015807	L-amino acid transport	3/988	69/18722	0.712735079565529	0.779456752502122	SLC38A2/ITGB1/SERINC3	3
GO:0033344	cholesterol efflux	3/988	69/18722	0.712735079565529	0.779456752502122	CAV1/SCARB1/ABCA1	3
GO:0060193	positive regulation of lipase activity	3/988	69/18722	0.712735079565529	0.779456752502122	FGFR1/GNAQ/RHOA	3
GO:0006541	glutamine metabolic process	1/988	23/18722	0.71283902553752	0.779456752502122	GLS	1
GO:0006833	water transport	1/988	23/18722	0.71283902553752	0.779456752502122	HYAL2	1
GO:0010888	negative regulation of lipid storage	1/988	23/18722	0.71283902553752	0.779456752502122	ABCA1	1
GO:0019430	removal of superoxide radicals	1/988	23/18722	0.71283902553752	0.779456752502122	CD36	1
GO:0023058	adaptation of signaling pathway	1/988	23/18722	0.71283902553752	0.779456752502122	APLNR	1
GO:0031280	negative regulation of cyclase activity	1/988	23/18722	0.71283902553752	0.779456752502122	GNAI2	1
GO:0032740	positive regulation of interleukin-17 production	1/988	23/18722	0.71283902553752	0.779456752502122	TGFB1	1
GO:0035929	steroid hormone secretion	1/988	23/18722	0.71283902553752	0.779456752502122	FZD4	1
GO:0035988	chondrocyte proliferation	1/988	23/18722	0.71283902553752	0.779456752502122	BMPR2	1
GO:0042438	melanin biosynthetic process	1/988	23/18722	0.71283902553752	0.779456752502122	RAPGEF2	1
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	1/988	23/18722	0.71283902553752	0.779456752502122	STAT3	1
GO:0045724	positive regulation of cilium assembly	1/988	23/18722	0.71283902553752	0.779456752502122	CCDC88A	1
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	1/988	23/18722	0.71283902553752	0.779456752502122	CHSY1	1
GO:0051590	positive regulation of neurotransmitter transport	1/988	23/18722	0.71283902553752	0.779456752502122	ITGB1	1
GO:0051882	mitochondrial depolarization	1/988	23/18722	0.71283902553752	0.779456752502122	KDR	1
GO:0060547	negative regulation of necrotic cell death	1/988	23/18722	0.71283902553752	0.779456752502122	CAV1	1
GO:0071218	cellular response to misfolded protein	1/988	23/18722	0.71283902553752	0.779456752502122	ATXN3	1
GO:0090208	positive regulation of triglyceride metabolic process	1/988	23/18722	0.71283902553752	0.779456752502122	SCARB1	1
GO:1904666	regulation of ubiquitin protein ligase activity	1/988	23/18722	0.71283902553752	0.779456752502122	PTEN	1
GO:0006790	sulfur compound metabolic process	16/988	339/18722	0.713012510063311	0.779485995772033	PAPSS2/NDNF/CLIC2/ANGPT1/MGST2/PDK4/MRI1/CHSY1/GNS/ACSL3/ELOVL5/HSD17B12/GLO1/ACAT1/DIP2A/FAR1	16
GO:0006354	DNA-templated transcription, elongation	4/988	91/18722	0.714172416785104	0.780272290819101	ZMYND11/ZMIZ1/ARID1A/CCNT1	4
GO:0051952	regulation of amine transport	4/988	91/18722	0.714172416785104	0.780272290819101	P2RY1/SYT11/ITGB1/SLC12A2	4
GO:0098661	inorganic anion transmembrane transport	4/988	91/18722	0.714172416785104	0.780272290819101	CLIC2/SLC12A2/XPR1/CLCN3	4
GO:0001754	eye photoreceptor cell differentiation	2/988	47/18722	0.717315349235341	0.78338386824386	TUG1/STAT3	2
GO:0006998	nuclear envelope organization	2/988	47/18722	0.717315349235341	0.78338386824386	SUN1/ZMPSTE24	2
GO:0016042	lipid catabolic process	15/988	320/18722	0.718483628069066	0.784498465016008	PLCB4/PLA1A/SCARF1/ENPP2/SCARB1/THRA/PLCB1/PRKCE/MGST2/DDHD1/CPT1A/ACAT1/LIPA/PRKAA1/PAFAH1B2	15
GO:0002548	monocyte chemotaxis	3/988	70/18722	0.721866698204255	0.788030394751542	PDGFB/DUSP1/MOSPD2	3
GO:0006497	protein lipidation	4/988	92/18722	0.722168091296418	0.788035517864949	UGCG/ABCA1/ZDHHC17/GOLGA7	4
GO:0034502	protein localization to chromosome	4/988	92/18722	0.722168091296418	0.788035517864949	RB1/ATRX/SLF2/NIPBL	4
GO:0050953	sensory perception of light stimulus	10/988	219/18722	0.724969159652514	0.790324976865704	ABLIM1/HMCN1/COL18A1/EPAS1/LAMB2/CRYBG3/EFEMP1/CHM/MYO9A/ATF6	10
GO:1903008	organelle disassembly	5/988	114/18722	0.725169682567901	0.790324976865704	KIF5B/HIF1A/RB1CC1/CTTN/VPS13C	5
GO:0000395	mRNA 5'-splice site recognition	1/988	24/18722	0.728011764334725	0.790324976865704	PSIP1	1
GO:0001779	natural killer cell differentiation	1/988	24/18722	0.728011764334725	0.790324976865704	HECTD1	1
GO:0002021	response to dietary excess	1/988	24/18722	0.728011764334725	0.790324976865704	ADRB1	1
GO:0002922	positive regulation of humoral immune response	1/988	24/18722	0.728011764334725	0.790324976865704	FCGR2B	1
GO:0006582	melanin metabolic process	1/988	24/18722	0.728011764334725	0.790324976865704	RAPGEF2	1
GO:0006817	phosphate ion transport	1/988	24/18722	0.728011764334725	0.790324976865704	XPR1	1
GO:0007035	vacuolar acidification	1/988	24/18722	0.728011764334725	0.790324976865704	CLIC4	1
GO:0010226	response to lithium ion	1/988	24/18722	0.728011764334725	0.790324976865704	FABP4	1
GO:0022410	circadian sleep/wake cycle process	1/988	24/18722	0.728011764334725	0.790324976865704	ADRB1	1
GO:0038095	Fc-epsilon receptor signaling pathway	1/988	24/18722	0.728011764334725	0.790324976865704	SOS1	1
GO:0051923	sulfation	1/988	24/18722	0.728011764334725	0.790324976865704	CHSY1	1
GO:0070935	3'-UTR-mediated mRNA stabilization	1/988	24/18722	0.728011764334725	0.790324976865704	ZFP36	1
GO:0071294	cellular response to zinc ion	1/988	24/18722	0.728011764334725	0.790324976865704	CREB1	1
GO:0071577	zinc ion transmembrane transport	1/988	24/18722	0.728011764334725	0.790324976865704	SLC30A1	1
GO:0072530	purine-containing compound transmembrane transport	1/988	24/18722	0.728011764334725	0.790324976865704	LRRC8C	1
GO:0090343	positive regulation of cell aging	1/988	24/18722	0.728011764334725	0.790324976865704	B2M	1
GO:0120255	olefinic compound biosynthetic process	1/988	24/18722	0.728011764334725	0.790324976865704	EGR1	1
GO:1903861	positive regulation of dendrite extension	1/988	24/18722	0.728011764334725	0.790324976865704	ITSN2	1
GO:0010569	regulation of double-strand break repair via homologous recombination	2/988	48/18722	0.728134494875895	0.790324976865704	ACTR2/RIF1	2
GO:0015804	neutral amino acid transport	2/988	48/18722	0.728134494875895	0.790324976865704	SLC38A2/SERINC3	2
GO:0042908	xenobiotic transport	2/988	48/18722	0.728134494875895	0.790324976865704	GJA1/SLC2A1	2
GO:0045005	DNA-dependent DNA replication maintenance of fidelity	2/988	48/18722	0.728134494875895	0.790324976865704	ATRX/FAM111A	2
GO:0045839	negative regulation of mitotic nuclear division	2/988	48/18722	0.728134494875895	0.790324976865704	DUSP1/APC	2
GO:0120009	intermembrane lipid transfer	2/988	48/18722	0.728134494875895	0.790324976865704	ABCA1/STARD4	2
GO:0071230	cellular response to amino acid stimulus	3/988	71/18722	0.730770475637306	0.793024058546551	COL4A1/FYN/CAPN2	3
GO:0006813	potassium ion transport	11/988	241/18722	0.731681355267128	0.793850359309433	CAV1/ITGB1/KIF5B/SLC12A2/PTEN/FLNA/PKD2/CRBN/GJA5/WNK1/NEDD4	11
GO:0048704	embryonic skeletal system morphogenesis	4/988	94/18722	0.737659027410572	0.800172504309773	TGFBR2/PCGF2/SMAD2/NIPBL	4
GO:0009066	aspartate family amino acid metabolic process	2/988	49/18722	0.738600422366758	0.800394078456218	MRI1/PLOD2	2
GO:0009395	phospholipid catabolic process	2/988	49/18722	0.738600422366758	0.800394078456218	ENPP2/SCARB1	2
GO:0021515	cell differentiation in spinal cord	2/988	49/18722	0.738600422366758	0.800394078456218	NOTCH1/GATA2	2
GO:1990573	potassium ion import across plasma membrane	2/988	49/18722	0.738600422366758	0.800394078456218	SLC12A2/WNK1	2
GO:1990748	cellular detoxification	5/988	116/18722	0.739105307554803	0.800394078456218	NXN/CLIC2/MGST2/TP53INP1/CD36	5
GO:0009582	detection of abiotic stimulus	6/988	138/18722	0.742156730318906	0.800394078456218	ITGA2/PIEZO1/GNAQ/FYN/PKD2/PTK2	6
GO:0001964	startle response	1/988	25/18722	0.742383588959674	0.800394078456218	PTEN	1
GO:0007274	neuromuscular synaptic transmission	1/988	25/18722	0.742383588959674	0.800394078456218	KIF1B	1
GO:0010996	response to auditory stimulus	1/988	25/18722	0.742383588959674	0.800394078456218	MDK	1
GO:0015874	norepinephrine transport	1/988	25/18722	0.742383588959674	0.800394078456218	P2RY1	1
GO:0032753	positive regulation of interleukin-4 production	1/988	25/18722	0.742383588959674	0.800394078456218	HLA-E	1
GO:0035902	response to immobilization stress	1/988	25/18722	0.742383588959674	0.800394078456218	ACTR2	1
GO:0044550	secondary metabolite biosynthetic process	1/988	25/18722	0.742383588959674	0.800394078456218	RAPGEF2	1
GO:0045822	negative regulation of heart contraction	1/988	25/18722	0.742383588959674	0.800394078456218	PDE4D	1
GO:0046339	diacylglycerol metabolic process	1/988	25/18722	0.742383588959674	0.800394078456218	DGKH	1
GO:0048143	astrocyte activation	1/988	25/18722	0.742383588959674	0.800394078456218	APP	1
GO:0050995	negative regulation of lipid catabolic process	1/988	25/18722	0.742383588959674	0.800394078456218	PRKAA1	1
GO:0051291	protein heterooligomerization	1/988	25/18722	0.742383588959674	0.800394078456218	PKD2	1
GO:0070199	establishment of protein localization to chromosome	1/988	25/18722	0.742383588959674	0.800394078456218	NIPBL	1
GO:0071450	cellular response to oxygen radical	1/988	25/18722	0.742383588959674	0.800394078456218	CD36	1
GO:0071451	cellular response to superoxide	1/988	25/18722	0.742383588959674	0.800394078456218	CD36	1
GO:0071459	protein localization to chromosome, centromeric region	1/988	25/18722	0.742383588959674	0.800394078456218	RB1	1
GO:0086013	membrane repolarization during cardiac muscle cell action potential	1/988	25/18722	0.742383588959674	0.800394078456218	FLNA	1
GO:0090382	phagosome maturation	1/988	25/18722	0.742383588959674	0.800394078456218	SYT11	1
GO:0099560	synaptic membrane adhesion	1/988	25/18722	0.742383588959674	0.800394078456218	SPARCL1	1
GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1/988	25/18722	0.742383588959674	0.800394078456218	THBS1	1
GO:1903959	regulation of anion transmembrane transport	1/988	25/18722	0.742383588959674	0.800394078456218	ITGB1	1
GO:1905563	negative regulation of vascular endothelial cell proliferation	1/988	25/18722	0.742383588959674	0.800394078456218	MEF2C	1
GO:2000311	regulation of AMPA receptor activity	1/988	25/18722	0.742383588959674	0.800394078456218	MEF2C	1
GO:2000316	regulation of T-helper 17 type immune response	1/988	25/18722	0.742383588959674	0.800394078456218	RC3H1	1
GO:0002532	production of molecular mediator involved in inflammatory response	4/988	95/18722	0.745155831942876	0.802894072876381	CD36/HIF1A/STAT3/SNAP23	4
GO:0008585	female gonad development	4/988	95/18722	0.745155831942876	0.802894072876381	FZD4/NR2F2/CTNNA1/SMAD4	4
GO:0036473	cell death in response to oxidative stress	4/988	95/18722	0.745155831942876	0.802894072876381	PML/FYN/NCOA7/HIF1A	4
GO:0008089	anterograde axonal transport	2/988	50/18722	0.748720238988143	0.805427685197452	KIF5B/KIF1B	2
GO:0038202	TORC1 signaling	2/988	50/18722	0.748720238988143	0.805427685197452	WAC/SMG1	2
GO:0045058	T cell selection	2/988	50/18722	0.748720238988143	0.805427685197452	RHOA/STAT3	2
GO:0045814	negative regulation of gene expression, epigenetic	2/988	50/18722	0.748720238988143	0.805427685197452	ATF7IP/BAZ2A	2
GO:0046460	neutral lipid biosynthetic process	2/988	50/18722	0.748720238988143	0.805427685197452	SCARB1/LPGAT1	2
GO:0046463	acylglycerol biosynthetic process	2/988	50/18722	0.748720238988143	0.805427685197452	SCARB1/LPGAT1	2
GO:0060688	regulation of morphogenesis of a branching structure	2/988	50/18722	0.748720238988143	0.805427685197452	MDK/RTN4	2
GO:1902930	regulation of alcohol biosynthetic process	2/988	50/18722	0.748720238988143	0.805427685197452	P2RY1/PRKAA1	2
GO:0042158	lipoprotein biosynthetic process	4/988	96/18722	0.752488153201945	0.809317082366619	UGCG/ABCA1/ZDHHC17/GOLGA7	4
GO:0001963	synaptic transmission, dopaminergic	1/988	26/18722	0.755996736208315	0.811106080138467	CRHBP	1
GO:0002092	positive regulation of receptor internalization	1/988	26/18722	0.755996736208315	0.811106080138467	ANGPT1	1
GO:0015985	energy coupled proton transport, down electrochemical gradient	1/988	26/18722	0.755996736208315	0.811106080138467	ATP6V1A	1
GO:0015986	ATP synthesis coupled proton transport	1/988	26/18722	0.755996736208315	0.811106080138467	ATP6V1A	1
GO:0032682	negative regulation of chemokine production	1/988	26/18722	0.755996736208315	0.811106080138467	KLF4	1
GO:0042278	purine nucleoside metabolic process	1/988	26/18722	0.755996736208315	0.811106080138467	NT5E	1
GO:0042537	benzene-containing compound metabolic process	1/988	26/18722	0.755996736208315	0.811106080138467	IDO1	1
GO:0043094	cellular metabolic compound salvage	1/988	26/18722	0.755996736208315	0.811106080138467	MRI1	1
GO:0051350	negative regulation of lyase activity	1/988	26/18722	0.755996736208315	0.811106080138467	GNAI2	1
GO:1903523	negative regulation of blood circulation	1/988	26/18722	0.755996736208315	0.811106080138467	PDE4D	1
GO:0007040	lysosome organization	3/988	74/18722	0.756136541574866	0.811106080138467	SCARB2/LYST/ABCA1	3
GO:0080171	lytic vacuole organization	3/988	74/18722	0.756136541574866	0.811106080138467	SCARB2/LYST/ABCA1	3
GO:1903201	regulation of oxidative stress-induced cell death	3/988	74/18722	0.756136541574866	0.811106080138467	FYN/NCOA7/HIF1A	3
GO:0010874	regulation of cholesterol efflux	2/988	51/18722	0.758501286063204	0.813314257482386	CAV1/ABCA1	2
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	2/988	51/18722	0.758501286063204	0.813314257482386	HLX/RC3H1	2
GO:0071826	ribonucleoprotein complex subunit organization	10/988	227/18722	0.764473486742995	0.819552605767667	KIF5B/DICER1/SETX/ADAR/CELF1/SF3B1/LUC7L3/RBM5/SCAF11/PSIP1	10
GO:0003333	amino acid transmembrane transport	4/988	98/18722	0.766664089709608	0.82048014223403	LRRC8C/SLC38A2/ITGB1/SLC16A2	4
GO:0043473	pigmentation	4/988	98/18722	0.766664089709608	0.82048014223403	MEF2C/LYST/RAB27A/RAB11A	4
GO:1902882	regulation of response to oxidative stress	4/988	98/18722	0.766664089709608	0.82048014223403	FYN/NCOA7/CD36/HIF1A	4
GO:0035176	social behavior	2/988	52/18722	0.767951094529429	0.82048014223403	PTEN/PCM1	2
GO:0043090	amino acid import	2/988	52/18722	0.767951094529429	0.82048014223403	ITGB1/SLC16A2	2
GO:0000737	DNA catabolic process, endonucleolytic	1/988	27/18722	0.7688912176282	0.82048014223403	DICER1	1
GO:0006783	heme biosynthetic process	1/988	27/18722	0.7688912176282	0.82048014223403	NFE2L1	1
GO:0008053	mitochondrial fusion	1/988	27/18722	0.7688912176282	0.82048014223403	VAT1	1
GO:0009651	response to salt stress	1/988	27/18722	0.7688912176282	0.82048014223403	ZFP36L1	1
GO:0015813	L-glutamate transmembrane transport	1/988	27/18722	0.7688912176282	0.82048014223403	ITGB1	1
GO:0018195	peptidyl-arginine modification	1/988	27/18722	0.7688912176282	0.82048014223403	FBXO11	1
GO:0032781	positive regulation of ATPase activity	1/988	27/18722	0.7688912176282	0.82048014223403	DNAJC10	1
GO:0032786	positive regulation of DNA-templated transcription, elongation	1/988	27/18722	0.7688912176282	0.82048014223403	CCNT1	1
GO:0034143	regulation of toll-like receptor 4 signaling pathway	1/988	27/18722	0.7688912176282	0.82048014223403	WDFY1	1
GO:0034698	response to gonadotropin	1/988	27/18722	0.7688912176282	0.82048014223403	NOTCH1	1
GO:0035235	ionotropic glutamate receptor signaling pathway	1/988	27/18722	0.7688912176282	0.82048014223403	APP	1
GO:0042403	thyroid hormone metabolic process	1/988	27/18722	0.7688912176282	0.82048014223403	SLC16A2	1
GO:0042745	circadian sleep/wake cycle	1/988	27/18722	0.7688912176282	0.82048014223403	ADRB1	1
GO:0046337	phosphatidylethanolamine metabolic process	1/988	27/18722	0.7688912176282	0.82048014223403	ETNK1	1
GO:0070861	regulation of protein exit from endoplasmic reticulum	1/988	27/18722	0.7688912176282	0.82048014223403	CD81	1
GO:1902883	negative regulation of response to oxidative stress	1/988	27/18722	0.7688912176282	0.82048014223403	NCOA7	1
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	1/988	27/18722	0.7688912176282	0.82048014223403	XRN1	1
GO:2000463	positive regulation of excitatory postsynaptic potential	1/988	27/18722	0.7688912176282	0.82048014223403	PTEN	1
GO:0006066	alcohol metabolic process	16/988	353/18722	0.769424793489507	0.820884615990412	IGF1/LEPR/P2RY1/SCARF1/PLPP1/SCARB1/SPTLC2/APP/PLPP3/NUDT3/PTEN/ABCA1/LBR/PRKAA1/CYB5R3/NFE2L1	16
GO:0002455	humoral immune response mediated by circulating immunoglobulin	5/988	121/18722	0.771658464866791	0.823102362524577	FCGR2B/CFI/CLU/CD81/CD46	5
GO:0140115	export across plasma membrane	3/988	76/18722	0.771951691225156	0.823249826096774	CALM1/GJA1/ABCA1	3
GO:0015837	amine transport	4/988	99/18722	0.773510404690116	0.824581029442885	P2RY1/SYT11/ITGB1/SLC12A2	4
GO:0021549	cerebellum development	4/988	99/18722	0.773510404690116	0.824581029442885	FCGR2B/FZD4/MDK/CRK	4
GO:0001541	ovarian follicle development	2/988	53/18722	0.777077344539059	0.827719040343189	CTNNA1/SMAD4	2
GO:0031279	regulation of cyclase activity	2/988	53/18722	0.777077344539059	0.827719040343189	GNAI2/CALM1	2
GO:0032784	regulation of DNA-templated transcription, elongation	2/988	53/18722	0.777077344539059	0.827719040343189	ZMYND11/CCNT1	2
GO:0071715	icosanoid transport	2/988	53/18722	0.777077344539059	0.827719040343189	EDN1/SLCO2A1	2
GO:0006626	protein targeting to mitochondrion	4/988	100/18722	0.780197617659393	0.829679948699878	ABLIM3/LEPROT/PRKAA1/SH3GLB1	4
GO:0006664	glycolipid metabolic process	4/988	100/18722	0.780197617659393	0.829679948699878	UGCG/ST3GAL5/PRKAA1/B4GALT5	4
GO:0019218	regulation of steroid metabolic process	4/988	100/18722	0.780197617659393	0.829679948699878	IGFBP7/EGR1/STARD4/PRKAA1	4
GO:0060079	excitatory postsynaptic potential	4/988	100/18722	0.780197617659393	0.829679948699878	MEF2C/APP/PTEN/PPP3CA	4
GO:0000303	response to superoxide	1/988	28/18722	0.781104936643089	0.829679948699878	CD36	1
GO:0000423	mitophagy	1/988	28/18722	0.781104936643089	0.829679948699878	VPS13C	1
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	1/988	28/18722	0.781104936643089	0.829679948699878	ATXN3	1
GO:0007271	synaptic transmission, cholinergic	1/988	28/18722	0.781104936643089	0.829679948699878	LAMA2	1
GO:0030262	apoptotic nuclear changes	1/988	28/18722	0.781104936643089	0.829679948699878	DICER1	1
GO:0032438	melanosome organization	1/988	28/18722	0.781104936643089	0.829679948699878	LYST	1
GO:0032958	inositol phosphate biosynthetic process	1/988	28/18722	0.781104936643089	0.829679948699878	P2RY1	1
GO:0062125	regulation of mitochondrial gene expression	1/988	28/18722	0.781104936643089	0.829679948699878	PRKAA1	1
GO:0071280	cellular response to copper ion	1/988	28/18722	0.781104936643089	0.829679948699878	APP	1
GO:0090200	positive regulation of release of cytochrome c from mitochondria	1/988	28/18722	0.781104936643089	0.829679948699878	TNFSF10	1
GO:0046942	carboxylic acid transport	12/988	273/18722	0.781795252413527	0.830247177293214	EDN1/CEACAM1/LRRC8C/SLCO2A1/SLC38A2/ITGB1/SERINC3/SLC12A2/GJA1/CD36/PRKAA1/SLC16A2	12
GO:0006584	catecholamine metabolic process	2/988	54/18722	0.785887828787706	0.833926517483079	NPR1/EPAS1	2
GO:0009712	catechol-containing compound metabolic process	2/988	54/18722	0.785887828787706	0.833926517483079	NPR1/EPAS1	2
GO:0051703	biological process involved in intraspecies interaction between organisms	2/988	54/18722	0.785887828787706	0.833926517483079	PTEN/PCM1	2
GO:0072348	sulfur compound transport	2/988	54/18722	0.785887828787706	0.833926517483079	LRRC8C/GJA1	2
GO:1903509	liposaccharide metabolic process	4/988	101/18722	0.786727365887135	0.834519028358676	UGCG/ST3GAL5/PRKAA1/B4GALT5	4
GO:0060271	cilium assembly	15/988	337/18722	0.786841204962432	0.834519028358676	ABLIM1/ABLIM3/EHD2/WWTR1/NOTCH1/EXOC5/FLNA/ACTR2/CYLD/PCM1/EHD4/CCDC88A/GSN/WDR11/MAP4	15
GO:0009064	glutamine family amino acid metabolic process	3/988	78/18722	0.78691750998656	0.834519028358676	GLS/DDAH2/ATP2B4	3
GO:0097237	cellular response to toxic substance	5/988	124/18722	0.789649603958273	0.837249240763742	NXN/CLIC2/MGST2/TP53INP1/CD36	5
GO:0000305	response to oxygen radical	1/988	29/18722	0.792673799518698	0.838781518534526	CD36	1
GO:0001773	myeloid dendritic cell activation	1/988	29/18722	0.792673799518698	0.838781518534526	TGFBR2	1
GO:0010458	exit from mitosis	1/988	29/18722	0.792673799518698	0.838781518534526	RGCC	1
GO:0031069	hair follicle morphogenesis	1/988	29/18722	0.792673799518698	0.838781518534526	NOTCH1	1
GO:0035066	positive regulation of histone acetylation	1/988	29/18722	0.792673799518698	0.838781518534526	SMAD4	1
GO:0042759	long-chain fatty acid biosynthetic process	1/988	29/18722	0.792673799518698	0.838781518534526	QKI	1
GO:0048753	pigment granule organization	1/988	29/18722	0.792673799518698	0.838781518534526	LYST	1
GO:0060441	epithelial tube branching involved in lung morphogenesis	1/988	29/18722	0.792673799518698	0.838781518534526	FOXF1	1
GO:0070198	protein localization to chromosome, telomeric region	1/988	29/18722	0.792673799518698	0.838781518534526	ATRX	1
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	1/988	29/18722	0.792673799518698	0.838781518534526	HIF1A	1
GO:0045833	negative regulation of lipid metabolic process	4/988	102/18722	0.793101386286948	0.839066832096448	CEACAM1/PPP2R5A/PDGFB/PRKAA1	4
GO:0001895	retina homeostasis	3/988	79/18722	0.794089917582261	0.839945368816601	B2M/SLC2A1/CLCN3	3
GO:0050905	neuromuscular process	6/988	148/18722	0.799296414585924	0.844974297953133	TCF15/ITPR1/HIPK2/APP/PTEN/ZMPSTE24	6
GO:0019395	fatty acid oxidation	4/988	103/18722	0.799321507382247	0.844974297953133	PDK4/CPT1A/ACAT1/PRKAA1	4
GO:0030004	cellular monovalent inorganic cation homeostasis	4/988	103/18722	0.799321507382247	0.844974297953133	SLC12A2/CLIC4/CLCN3/MAPK1	4
GO:1901264	carbohydrate derivative transport	3/988	80/18722	0.801059825505408	0.846643412870022	LRRC8C/SCARB1/GJA1	3
GO:0007281	germ cell development	12/988	278/18722	0.801586495171292	0.846666447929321	JAM2/IGF1/RPS6KA2/ANGPT2/SMAD5/MDK/JAM3/CDC25B/FNDC3A/QKI/MFSD14A/CELF1	12
GO:0010518	positive regulation of phospholipase activity	2/988	56/18722	0.802593037346999	0.846666447929321	FGFR1/GNAQ	2
GO:0031529	ruffle organization	2/988	56/18722	0.802593037346999	0.846666447929321	CAV1/RDX	2
GO:0048255	mRNA stabilization	2/988	56/18722	0.802593037346999	0.846666447929321	PABPC1/ZFP36	2
GO:0050433	regulation of catecholamine secretion	2/988	56/18722	0.802593037346999	0.846666447929321	P2RY1/SYT11	2
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	1/988	30/18722	0.803631820493155	0.846666447929321	DICER1	1
GO:0007202	activation of phospholipase C activity	1/988	30/18722	0.803631820493155	0.846666447929321	GNAQ	1
GO:0008209	androgen metabolic process	1/988	30/18722	0.803631820493155	0.846666447929321	SCARB1	1
GO:0009072	aromatic amino acid family metabolic process	1/988	30/18722	0.803631820493155	0.846666447929321	IDO1	1
GO:0010453	regulation of cell fate commitment	1/988	30/18722	0.803631820493155	0.846666447929321	HES1	1
GO:0010669	epithelial structure maintenance	1/988	30/18722	0.803631820493155	0.846666447929321	LDB2	1
GO:0034368	protein-lipid complex remodeling	1/988	30/18722	0.803631820493155	0.846666447929321	SCARB1	1
GO:0034369	plasma lipoprotein particle remodeling	1/988	30/18722	0.803631820493155	0.846666447929321	SCARB1	1
GO:0090151	establishment of protein localization to mitochondrial membrane	1/988	30/18722	0.803631820493155	0.846666447929321	CALM1	1
GO:0099068	postsynapse assembly	1/988	30/18722	0.803631820493155	0.846666447929321	PTEN	1
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	1/988	30/18722	0.803631820493155	0.846666447929321	ATF6	1
GO:0030641	regulation of cellular pH	3/988	81/18722	0.807830732346537	0.850921445612692	CLIC4/CLCN3/MAPK1	3
GO:0048515	spermatid differentiation	7/988	172/18722	0.808746157077427	0.851716809356719	JAM2/JAM3/FNDC3A/QKI/MFSD14A/CELF1/DDX6	7
GO:0050879	multicellular organismal movement	2/988	57/18722	0.810503626444374	0.853229342780919	ITPR1/HIPK2	2
GO:0050881	musculoskeletal movement	2/988	57/18722	0.810503626444374	0.853229342780919	ITPR1/HIPK2	2
GO:0000041	transition metal ion transport	4/988	105/18722	0.811307777733097	0.853906660455362	B2M/SLC30A1/SLC30A7/ATOX1	4
GO:1901605	alpha-amino acid metabolic process	8/988	195/18722	0.813537179977494	0.855226979423199	IDO1/SERINC3/GLS/MRI1/DDAH2/PLOD2/ACAT1/ATP2B4	8
GO:0006779	porphyrin-containing compound biosynthetic process	1/988	31/18722	0.814011221378708	0.855226979423199	NFE2L1	1
GO:0030149	sphingolipid catabolic process	1/988	31/18722	0.814011221378708	0.855226979423199	ENPP2	1
GO:0030201	heparan sulfate proteoglycan metabolic process	1/988	31/18722	0.814011221378708	0.855226979423199	SULF2	1
GO:0033014	tetrapyrrole biosynthetic process	1/988	31/18722	0.814011221378708	0.855226979423199	NFE2L1	1
GO:0051443	positive regulation of ubiquitin-protein transferase activity	1/988	31/18722	0.814011221378708	0.855226979423199	PTEN	1
GO:0055075	potassium ion homeostasis	1/988	31/18722	0.814011221378708	0.855226979423199	SLC12A2	1
GO:0070528	protein kinase C signaling	1/988	31/18722	0.814011221378708	0.855226979423199	PDGFB	1
GO:0097106	postsynaptic density organization	1/988	31/18722	0.814011221378708	0.855226979423199	PTEN	1
GO:0006766	vitamin metabolic process	4/988	106/18722	0.817077974041845	0.858109568625995	NNMT/SLC2A1/CD320/SLC2A3	4
GO:0099565	chemical synaptic transmission, postsynaptic	4/988	106/18722	0.817077974041845	0.858109568625995	MEF2C/APP/PTEN/PPP3CA	4
GO:0090305	nucleic acid phosphodiester bond hydrolysis	11/988	261/18722	0.817869867393732	0.858705243888961	RNASE1/ENPP2/ENDOD1/DICER1/ZFP36/CNOT6L/PLSCR1/G3BP1/CNOT8/CNOT2/XRN1	11
GO:0042743	hydrogen peroxide metabolic process	2/988	58/18722	0.818130127884419	0.858705243888961	FYN/STAT3	2
GO:0050432	catecholamine secretion	2/988	58/18722	0.818130127884419	0.858705243888961	P2RY1/SYT11	2
GO:0042445	hormone metabolic process	9/988	218/18722	0.818561562835755	0.858988348831199	HSD17B2/ECE1/PCSK5/SCARB1/HIF1A/HSD17B12/EGR1/ZMPSTE24/SLC16A2	9
GO:0050871	positive regulation of B cell activation	6/988	152/18722	0.819219281921206	0.859169363389032	MEF2C/CD81/TGFB1/CD320/KMT5B/RIF1	6
GO:0090501	RNA phosphodiester bond hydrolysis	6/988	152/18722	0.819219281921206	0.859169363389032	RNASE1/DICER1/CNOT6L/CNOT8/CNOT2/XRN1	6
GO:0098754	detoxification	6/988	152/18722	0.819219281921206	0.859169363389032	NXN/CLIC2/MGST2/TP53INP1/CD36/SLC30A1	6
GO:0050954	sensory perception of mechanical stimulus	7/988	175/18722	0.822398630991953	0.861577255391939	FZD4/ITGA2/SCARB2/FYN/CCDC50/FBXO11/NIPBL	7
GO:0071805	potassium ion transmembrane transport	9/988	219/18722	0.822572665829322	0.861577255391939	CAV1/ITGB1/SLC12A2/PTEN/FLNA/PKD2/CRBN/WNK1/NEDD4	9
GO:0000018	regulation of DNA recombination	4/988	107/18722	0.822702351203302	0.861577255391939	TGFB1/ACTR2/KMT5B/RIF1	4
GO:0015850	organic hydroxy compound transport	12/988	284/18722	0.823573234440719	0.861577255391939	LRP6/P2RY1/CEACAM1/CAV1/SCARB1/SYT11/CLU/OSBPL10/CD36/ABCA1/STARD4/PRKAA1	12
GO:0006308	DNA catabolic process	1/988	32/18722	0.823842525925165	0.861577255391939	DICER1	1
GO:0009954	proximal/distal pattern formation	1/988	32/18722	0.823842525925165	0.861577255391939	CHSY1	1
GO:0019835	cytolysis	1/988	32/18722	0.823842525925165	0.861577255391939	TGFB1	1
GO:0030431	sleep	1/988	32/18722	0.823842525925165	0.861577255391939	ADRB1	1
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	1/988	32/18722	0.823842525925165	0.861577255391939	ZMYND11	1
GO:0034367	protein-containing complex remodeling	1/988	32/18722	0.823842525925165	0.861577255391939	SCARB1	1
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	1/988	32/18722	0.823842525925165	0.861577255391939	HLX	1
GO:0045761	regulation of adenylate cyclase activity	1/988	32/18722	0.823842525925165	0.861577255391939	GNAI2	1
GO:0045879	negative regulation of smoothened signaling pathway	1/988	32/18722	0.823842525925165	0.861577255391939	RB1	1
GO:0097345	mitochondrial outer membrane permeabilization	1/988	32/18722	0.823842525925165	0.861577255391939	HSPA1A	1
GO:0007338	single fertilization	6/988	153/18722	0.823948128273917	0.861577255391939	PLCB1/MYH9/ASH1L/CD9/CD46/SMAD4	6
GO:0033013	tetrapyrrole metabolic process	2/988	59/18722	0.825480458911513	0.863009682688045	CD320/NFE2L1	2
GO:0022618	ribonucleoprotein complex assembly	9/988	220/18722	0.826515573148356	0.86392182695082	DICER1/SETX/ADAR/CELF1/SF3B1/LUC7L3/RBM5/SCAF11/PSIP1	9
GO:0032370	positive regulation of lipid transport	3/988	84/18722	0.826985588563504	0.864243054583776	EDN1/CAV1/ABCA1	3
GO:0034440	lipid oxidation	4/988	108/18722	0.82818308589281	0.865324262836862	PDK4/CPT1A/ACAT1/PRKAA1	4
GO:0042391	regulation of membrane potential	19/988	434/18722	0.830201287108966	0.867262386848147	EDN1/KDR/MEF2C/CAV1/PIEZO1/KIF5B/APP/ADRB1/GNAQ/CALM1/GJA1/PTEN/FLNA/CD36/PPP3CA/GJA5/NEDD4/JUN/ZMPSTE24	19
GO:0006333	chromatin assembly or disassembly	7/988	177/18722	0.831069052406643	0.867277581159749	ATRX/RSF1/KAT6A/UBN2/ARID1A/CHD3/BAZ2A	7
GO:0006289	nucleotide-excision repair	2/988	60/18722	0.83256249315259	0.867277581159749	ATXN3/POLK	2
GO:0009620	response to fungus	2/988	60/18722	0.83256249315259	0.867277581159749	CRK/BCL10	2
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	2/988	60/18722	0.83256249315259	0.867277581159749	TAOK1/FOXN3	2
GO:0019731	antibacterial humoral response	2/988	60/18722	0.83256249315259	0.867277581159749	HLA-E/HLA-A	2
GO:0051965	positive regulation of synapse assembly	2/988	60/18722	0.83256249315259	0.867277581159749	ADGRL2/AGRN	2
GO:0006536	glutamate metabolic process	1/988	33/18722	0.833154649220293	0.867277581159749	GLS	1
GO:0006654	phosphatidic acid biosynthetic process	1/988	33/18722	0.833154649220293	0.867277581159749	DGKH	1
GO:0010984	regulation of lipoprotein particle clearance	1/988	33/18722	0.833154649220293	0.867277581159749	HNRNPK	1
GO:0032633	interleukin-4 production	1/988	33/18722	0.833154649220293	0.867277581159749	HLA-E	1
GO:0032673	regulation of interleukin-4 production	1/988	33/18722	0.833154649220293	0.867277581159749	HLA-E	1
GO:0036336	dendritic cell migration	1/988	33/18722	0.833154649220293	0.867277581159749	CDC42	1
GO:0060122	inner ear receptor cell stereocilium organization	1/988	33/18722	0.833154649220293	0.867277581159749	HES1	1
GO:0099084	postsynaptic specialization organization	1/988	33/18722	0.833154649220293	0.867277581159749	PTEN	1
GO:0099174	regulation of presynapse organization	1/988	33/18722	0.833154649220293	0.867277581159749	APP	1
GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	1/988	33/18722	0.833154649220293	0.867277581159749	MAP4	1
GO:1902275	regulation of chromatin organization	1/988	33/18722	0.833154649220293	0.867277581159749	ATF7IP	1
GO:1905606	regulation of presynapse assembly	1/988	33/18722	0.833154649220293	0.867277581159749	APP	1
GO:0018958	phenol-containing compound metabolic process	4/988	110/18722	0.838722577275311	0.872902494217565	NPR1/EPAS1/RAPGEF2/SLC16A2	4
GO:0019748	secondary metabolic process	2/988	61/18722	0.839384043184211	0.873419791850055	PAM/RAPGEF2	2
GO:0000038	very long-chain fatty acid metabolic process	1/988	34/18722	0.841974982387951	0.875008551481795	ELOVL5	1
GO:0000096	sulfur amino acid metabolic process	1/988	34/18722	0.841974982387951	0.875008551481795	MRI1	1
GO:0002446	neutrophil mediated immunity	1/988	34/18722	0.841974982387951	0.875008551481795	KMT2E	1
GO:0006270	DNA replication initiation	1/988	34/18722	0.841974982387951	0.875008551481795	PURA	1
GO:0007616	long-term memory	1/988	34/18722	0.841974982387951	0.875008551481795	PJA2	1
GO:0009112	nucleobase metabolic process	1/988	34/18722	0.841974982387951	0.875008551481795	MAPK1	1
GO:1903046	meiotic cell cycle process	8/988	202/18722	0.84206395240492	0.875008551481795	RPS6KA2/PLCB1/CDC25B/ATRX/PRKAR1A/MYH9/ACTR2/SUN1	8
GO:0015698	inorganic anion transport	7/988	180/18722	0.843443678556987	0.876270843046101	LRRC8C/CLIC2/TTYH3/SLC12A2/CLIC4/XPR1/CLCN3	7
GO:0071103	DNA conformation change	12/988	290/18722	0.84368268265162	0.876347753274425	HHEX/CHD9/ATRX/SETX/PURA/RECQL/RSF1/G3BP1/KAT6A/UBN2/CHD3/BAZ2A	12
GO:0051262	protein tetramerization	3/988	87/18722	0.844481904569172	0.87700642757995	B2M/GLS/PKD2	3
GO:0046148	pigment biosynthetic process	2/988	62/18722	0.845952845057408	0.878019052939615	RAPGEF2/NFE2L1	2
GO:0046173	polyol biosynthetic process	2/988	62/18722	0.845952845057408	0.878019052939615	P2RY1/SPTLC2	2
GO:1902750	negative regulation of cell cycle G2/M phase transition	2/988	62/18722	0.845952845057408	0.878019052939615	TAOK1/FOXN3	2
GO:0006691	leukotriene metabolic process	1/988	35/18722	0.850329472831053	0.880668777476809	MGST2	1
GO:0009119	ribonucleoside metabolic process	1/988	35/18722	0.850329472831053	0.880668777476809	NT5E	1
GO:0032205	negative regulation of telomere maintenance	1/988	35/18722	0.850329472831053	0.880668777476809	XRN1	1
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	1/988	35/18722	0.850329472831053	0.880668777476809	CNOT2	1
GO:0042462	eye photoreceptor cell development	1/988	35/18722	0.850329472831053	0.880668777476809	TUG1	1
GO:0045922	negative regulation of fatty acid metabolic process	1/988	35/18722	0.850329472831053	0.880668777476809	CEACAM1	1
GO:0046471	phosphatidylglycerol metabolic process	1/988	35/18722	0.850329472831053	0.880668777476809	LPGAT1	1
GO:0071108	protein K48-linked deubiquitination	1/988	35/18722	0.850329472831053	0.880668777476809	ATXN3	1
GO:0086005	ventricular cardiac muscle cell action potential	1/988	35/18722	0.850329472831053	0.880668777476809	CAV1	1
GO:0090181	regulation of cholesterol metabolic process	1/988	35/18722	0.850329472831053	0.880668777476809	PRKAA1	1
GO:0098810	neurotransmitter reuptake	1/988	35/18722	0.850329472831053	0.880668777476809	ITGB1	1
GO:1902373	negative regulation of mRNA catabolic process	2/988	63/18722	0.852276544622556	0.882513256342109	PABPC1/ZFP36	2
GO:0007586	digestion	5/988	137/18722	0.855070856134553	0.884889224193794	SCARB1/UGCG/CD36/F11R/WNK1	5
GO:0034754	cellular hormone metabolic process	5/988	137/18722	0.855070856134553	0.884889224193794	HSD17B2/ECE1/SCARB1/HSD17B12/EGR1	5
GO:0060078	regulation of postsynaptic membrane potential	5/988	137/18722	0.855070856134553	0.884889224193794	MEF2C/APP/ADRB1/PTEN/PPP3CA	5
GO:0006699	bile acid biosynthetic process	1/988	36/18722	0.858242700253482	0.887258724541165	STARD4	1
GO:0008207	C21-steroid hormone metabolic process	1/988	36/18722	0.858242700253482	0.887258724541165	EGR1	1
GO:0010092	specification of animal organ identity	1/988	36/18722	0.858242700253482	0.887258724541165	MEF2C	1
GO:0014046	dopamine secretion	1/988	36/18722	0.858242700253482	0.887258724541165	SYT11	1
GO:0014059	regulation of dopamine secretion	1/988	36/18722	0.858242700253482	0.887258724541165	SYT11	1
GO:0045670	regulation of osteoclast differentiation	2/988	64/18722	0.858362685507727	0.887258724541165	CREB1/KLF10	2
GO:0000724	double-strand break repair via homologous recombination	5/988	138/18722	0.85931574808251	0.888071061053364	REV3L/ACTR2/RECQL/NIPBL/RIF1	5
GO:0006959	humoral immune response	13/988	317/18722	0.85985811937451	0.888458729841937	A2M/FCGR2B/CFI/MEF2C/HLA-E/HLA-A/NOTCH1/RGCC/ST6GAL1/CLU/CD81/CD59/CD46	13
GO:0043489	RNA stabilization	2/988	65/18722	0.86421869861437	0.892617096449452	PABPC1/ZFP36	2
GO:0046503	glycerolipid catabolic process	2/988	65/18722	0.86421869861437	0.892617096449452	ENPP2/SCARB1	2
GO:0007340	acrosome reaction	1/988	37/18722	0.865737948682764	0.893144296640676	PLCB1	1
GO:0021532	neural tube patterning	1/988	37/18722	0.865737948682764	0.893144296640676	HES1	1
GO:0043029	T cell homeostasis	1/988	37/18722	0.865737948682764	0.893144296640676	RC3H1	1
GO:0043368	positive T cell selection	1/988	37/18722	0.865737948682764	0.893144296640676	STAT3	1
GO:0046473	phosphatidic acid metabolic process	1/988	37/18722	0.865737948682764	0.893144296640676	DGKH	1
GO:0050775	positive regulation of dendrite morphogenesis	1/988	37/18722	0.865737948682764	0.893144296640676	ACTR2	1
GO:0007006	mitochondrial membrane organization	4/988	116/18722	0.867132823648272	0.894062414444802	CALM1/STAT3/ATF2/HSPA1A	4
GO:0031123	RNA 3'-end processing	4/988	116/18722	0.867132823648272	0.894062414444802	ZFP36L1/APP/PABPC1/CCNT1	4
GO:0033559	unsaturated fatty acid metabolic process	4/988	116/18722	0.867132823648272	0.894062414444802	EDN1/FABP5/ZADH2/ELOVL5	4
GO:0000725	recombinational repair	5/988	140/18722	0.86749365834104	0.894087371576951	REV3L/ACTR2/RECQL/NIPBL/RIF1	5
GO:0046165	alcohol biosynthetic process	5/988	140/18722	0.86749365834104	0.894087371576951	P2RY1/SPTLC2/LBR/PRKAA1/CYB5R3	5
GO:0050909	sensory perception of taste	2/988	66/18722	0.869851893003947	0.896170142675905	GNB1/CD36	2
GO:1905953	negative regulation of lipid localization	2/988	66/18722	0.869851893003947	0.896170142675905	THBS1/ABCA1	2
GO:0006338	chromatin remodeling	10/988	255/18722	0.870835230169604	0.897009257836132	RB1/ATRX/BAZ2B/RSF1/KAT6A/UBN2/BPTF/ARID1A/CHD3/BAZ2A	10
GO:0010719	negative regulation of epithelial to mesenchymal transition	1/988	38/18722	0.872837274703712	0.898722931425881	PTEN	1
GO:1901031	regulation of response to reactive oxygen species	1/988	38/18722	0.872837274703712	0.898722931425881	CD36	1
GO:0007286	spermatid development	6/988	165/18722	0.873312841226279	0.89903833577403	JAM2/JAM3/FNDC3A/QKI/MFSD14A/CELF1	6
GO:0006325	chromatin organization	17/988	409/18722	0.874725744222524	0.900318378862632	MECOM/LOXL2/CHD9/KMT2E/RB1/ATRX/BAZ2B/ZMYND11/RSF1/ATF7IP/KAT6A/UBN2/NR3C1/BPTF/ARID1A/CHD3/BAZ2A	17
GO:0033273	response to vitamin	3/988	93/18722	0.87491135713652	0.900334972706159	SPARC/ITGA2/CCND1	3
GO:0006413	translational initiation	4/988	118/18722	0.875597330458212	0.900866360525667	EIF4G3/EIF2AK2/CSDE1/EIF4G2	4
GO:0042417	dopamine metabolic process	1/988	39/18722	0.879561572102167	0.904419487225457	NPR1	1
GO:0086091	regulation of heart rate by cardiac conduction	1/988	39/18722	0.879561572102167	0.904419487225457	CAV1	1
GO:0090207	regulation of triglyceride metabolic process	1/988	39/18722	0.879561572102167	0.904419487225457	SCARB1	1
GO:0034728	nucleosome organization	6/988	167/18722	0.880299780556314	0.905003374165887	ATRX/RSF1/KAT6A/UBN2/BPTF/ARID1A	6
GO:0006631	fatty acid metabolic process	16/988	390/18722	0.880572465318268	0.905108540203297	EDN1/CEACAM1/CAV1/PAM/FABP5/PDK4/ZADH2/CPT1A/LPGAT1/ACSL3/ELOVL5/CD36/QKI/HSD17B12/ACAT1/PRKAA1	16
GO:0070192	chromosome organization involved in meiotic cell cycle	2/988	69/18722	0.885485670304029	0.909911740732243	ATRX/SUN1	2
GO:0009069	serine family amino acid metabolic process	1/988	40/18722	0.885930633107523	0.909911740732243	SERINC3	1
GO:0042073	intraciliary transport	1/988	40/18722	0.885930633107523	0.909911740732243	PCM1	1
GO:0097352	autophagosome maturation	1/988	40/18722	0.885930633107523	0.909911740732243	CALM1	1
GO:0051321	meiotic cell cycle	10/988	261/18722	0.887671335646351	0.911523320114714	RPS6KA2/PLCB1/DUSP1/CDC25B/ATRX/PRKAR1A/MYH9/ACTR2/SUN1/STAG2	10
GO:0042742	defense response to bacterium	14/988	350/18722	0.888590155266949	0.912204731753246	GBP4/SELP/FOXP1/SYT11/HLA-E/HLA-A/STAB1/SHC1/OAS2/LYST/TNFRSF14/ISG15/CD36/PLAC8	14
GO:0002377	immunoglobulin production	8/988	216/18722	0.888678367248315	0.912204731753246	FCGR2B/HLA-E/B2M/PKN1/TGFB1/TMBIM6/KMT5B/RIF1	8
GO:0007099	centriole replication	1/988	41/18722	0.891963206412831	0.915222822573876	PLK2	1
GO:0009167	purine ribonucleoside monophosphate metabolic process	1/988	41/18722	0.891963206412831	0.915222822573876	NT5E	1
GO:0006690	icosanoid metabolic process	4/988	123/18722	0.894743306118409	0.91789811550811	EDN1/FABP5/MGST2/ZADH2	4
GO:0015711	organic anion transport	14/988	354/18722	0.897481679148653	0.919487177203548	EDN1/CEACAM1/LRRC8C/SLCO2A1/SLC38A2/ITGB1/SERINC3/SLC12A2/GJA1/CD36/SLC2A1/PRKAA1/SLC2A3/SLC16A2	14
GO:0006040	amino sugar metabolic process	1/988	42/18722	0.897677052141867	0.919487177203548	ST6GAL1	1
GO:0042168	heme metabolic process	1/988	42/18722	0.897677052141867	0.919487177203548	NFE2L1	1
GO:0045292	mRNA cis splicing, via spliceosome	1/988	42/18722	0.897677052141867	0.919487177203548	PSIP1	1
GO:0055090	acylglycerol homeostasis	1/988	42/18722	0.897677052141867	0.919487177203548	SCARB1	1
GO:0070328	triglyceride homeostasis	1/988	42/18722	0.897677052141867	0.919487177203548	SCARB1	1
GO:0071312	cellular response to alkaloid	1/988	42/18722	0.897677052141867	0.919487177203548	CRHBP	1
GO:1903432	regulation of TORC1 signaling	1/988	42/18722	0.897677052141867	0.919487177203548	WAC	1
GO:0002534	cytokine production involved in inflammatory response	2/988	72/18722	0.899364079113839	0.920860059416483	HIF1A/STAT3	2
GO:1900015	regulation of cytokine production involved in inflammatory response	2/988	72/18722	0.899364079113839	0.920860059416483	HIF1A/STAT3	2
GO:0021510	spinal cord development	3/988	99/18722	0.899942858625997	0.92127509443463	NOTCH1/GATA2/PKD2	3
GO:0001504	neurotransmitter uptake	1/988	43/18722	0.903088993923657	0.923961620901862	ITGB1	1
GO:0042181	ketone biosynthetic process	1/988	43/18722	0.903088993923657	0.923961620901862	EGR1	1
GO:0046717	acid secretion	1/988	43/18722	0.903088993923657	0.923961620901862	PRKAA1	1
GO:0051937	catecholamine transport	2/988	73/18722	0.903630588520931	0.924159739357563	P2RY1/SYT11	2
GO:0070988	demethylation	2/988	73/18722	0.903630588520931	0.924159739357563	KDM7A/JMJD1C	2
GO:0031497	chromatin assembly	5/988	151/18722	0.90561402870313	0.92600995581733	ATRX/RSF1/KAT6A/UBN2/BAZ2A	5
GO:0006635	fatty acid beta-oxidation	2/988	74/18722	0.907727645380544	0.927598137131195	CPT1A/ACAT1	2
GO:0009126	purine nucleoside monophosphate metabolic process	1/988	44/18722	0.908214968226533	0.927598137131195	NT5E	1
GO:0021517	ventral spinal cord development	1/988	44/18722	0.908214968226533	0.927598137131195	GATA2	1
GO:0032620	interleukin-17 production	1/988	44/18722	0.908214968226533	0.927598137131195	TGFB1	1
GO:0032660	regulation of interleukin-17 production	1/988	44/18722	0.908214968226533	0.927598137131195	TGFB1	1
GO:0044058	regulation of digestive system process	1/988	44/18722	0.908214968226533	0.927598137131195	WNK1	1
GO:0051453	regulation of intracellular pH	2/988	75/18722	0.911661229760544	0.930760033151645	CLIC4/CLCN3	2
GO:1902369	negative regulation of RNA catabolic process	2/988	75/18722	0.911661229760544	0.930760033151645	PABPC1/ZFP36	2
GO:0032309	icosanoid secretion	1/988	45/18722	0.913070071095801	0.93130342120985	EDN1	1
GO:0045910	negative regulation of DNA recombination	1/988	45/18722	0.913070071095801	0.93130342120985	RIF1	1
GO:0046189	phenol-containing compound biosynthetic process	1/988	45/18722	0.913070071095801	0.93130342120985	RAPGEF2	1
GO:0060119	inner ear receptor cell development	1/988	45/18722	0.913070071095801	0.93130342120985	HES1	1
GO:0098534	centriole assembly	1/988	45/18722	0.913070071095801	0.93130342120985	PLK2	1
GO:0007605	sensory perception of sound	5/988	154/18722	0.914190505736258	0.932162001970205	FZD4/SCARB2/CCDC50/FBXO11/NIPBL	5
GO:0006334	nucleosome assembly	4/988	129/18722	0.914262806902253	0.932162001970205	ATRX/RSF1/KAT6A/UBN2	4
GO:0006984	ER-nucleus signaling pathway	1/988	46/18722	0.917668602431527	0.935275444381479	ATF6	1
GO:0031648	protein destabilization	1/988	46/18722	0.917668602431527	0.935275444381479	GSN	1
GO:1905952	regulation of lipid localization	6/988	181/18722	0.920644150371377	0.938128088772828	EDN1/CAV1/SCARB1/THBS1/CD36/ABCA1	6
GO:0032369	negative regulation of lipid transport	1/988	47/18722	0.922024107935792	0.938864996302105	THBS1	1
GO:0050885	neuromuscular process controlling balance	1/988	47/18722	0.922024107935792	0.938864996302105	APP	1
GO:0070646	protein modification by small protein removal	5/988	157/18722	0.922074300773359	0.938864996302105	ATXN3/CYLD/SENP7/USP31/SENP6	5
GO:1902600	proton transmembrane transport	5/988	157/18722	0.922074300773359	0.938864996302105	COX7A1/TMSB4X/ACTN4/ATP6V1A/CLCN3	5
GO:0032371	regulation of sterol transport	2/988	78/18722	0.922538572069969	0.938977753369548	CAV1/ABCA1	2
GO:0032374	regulation of cholesterol transport	2/988	78/18722	0.922538572069969	0.938977753369548	CAV1/ABCA1	2
GO:0035036	sperm-egg recognition	1/988	48/18722	0.92614941885196	0.942472358801075	CD9	1
GO:0006958	complement activation, classical pathway	3/988	108/18722	0.929082656385541	0.944638840386101	CFI/CLU/CD46	3
GO:0140013	meiotic nuclear division	6/988	185/18722	0.929735680404733	0.944638840386101	RPS6KA2/PLCB1/CDC25B/PRKAR1A/ACTR2/SUN1	6
GO:0000959	mitochondrial RNA metabolic process	1/988	49/18722	0.930056689612068	0.944638840386101	PRKAA1	1
GO:0006778	porphyrin-containing compound metabolic process	1/988	49/18722	0.930056689612068	0.944638840386101	NFE2L1	1
GO:0007602	phototransduction	1/988	49/18722	0.930056689612068	0.944638840386101	GNAQ	1
GO:0008206	bile acid metabolic process	1/988	49/18722	0.930056689612068	0.944638840386101	STARD4	1
GO:0021695	cerebellar cortex development	1/988	49/18722	0.930056689612068	0.944638840386101	MDK	1
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1/988	49/18722	0.930056689612068	0.944638840386101	WWTR1	1
GO:0042461	photoreceptor cell development	1/988	49/18722	0.930056689612068	0.944638840386101	TUG1	1
GO:0050832	defense response to fungus	1/988	49/18722	0.930056689612068	0.944638840386101	BCL10	1
GO:0042157	lipoprotein metabolic process	4/988	135/18722	0.930486922309152	0.944895150316616	UGCG/ABCA1/ZDHHC17/GOLGA7	4
GO:0007080	mitotic metaphase plate congression	1/988	50/18722	0.933757433502352	0.947853905362984	RAB11A	1
GO:0015872	dopamine transport	1/988	50/18722	0.933757433502352	0.947853905362984	SYT11	1
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	2/988	82/18722	0.9350882334824	0.949023442158676	RNASE1/DICER1	2
GO:0009584	detection of visible light	1/988	51/18722	0.937262556451135	0.950685258710795	GNAQ	1
GO:0051339	regulation of lyase activity	1/988	51/18722	0.937262556451135	0.950685258710795	GNAI2	1
GO:0060632	regulation of microtubule-based movement	1/988	51/18722	0.937262556451135	0.950685258710795	LAMP1	1
GO:0007129	homologous chromosome pairing at meiosis	1/988	52/18722	0.940582389037836	0.953540390483554	SUN1	1
GO:0015844	monoamine transport	2/988	84/18722	0.940615897239048	0.953540390483554	P2RY1/SYT11	2
GO:0042440	pigment metabolic process	2/988	84/18722	0.940615897239048	0.953540390483554	RAPGEF2/NFE2L1	2
GO:0006414	translational elongation	1/988	55/18722	0.949525445890893	0.96220510655712	SECISBP2L	1
GO:0042220	response to cocaine	1/988	55/18722	0.949525445890893	0.96220510655712	CRHBP	1
GO:0050829	defense response to Gram-negative bacterium	2/988	88/18722	0.950357556304016	0.962864646020776	SELP/TNFRSF14	2
GO:0051205	protein insertion into membrane	1/988	57/18722	0.954727182045621	0.967107320943237	TRAM1	1
GO:0042147	retrograde transport, endosome to Golgi	2/988	91/18722	0.956642143866213	0.968862358096725	SPAG9/TMEM87B	2
GO:0006826	iron ion transport	1/988	58/18722	0.957123621592308	0.968980498932407	B2M	1
GO:0009161	ribonucleoside monophosphate metabolic process	1/988	58/18722	0.957123621592308	0.968980498932407	NT5E	1
GO:0032368	regulation of lipid transport	4/988	149/18722	0.958084623063133	0.969768581880976	EDN1/CAV1/THBS1/ABCA1	4
GO:0035249	synaptic transmission, glutamatergic	2/988	92/18722	0.958562265023214	0.970067203620368	MEF2C/CLCN3	2
GO:0045132	meiotic chromosome segregation	2/988	93/18722	0.960400746515229	0.971742621997885	ACTR2/SUN1	2
GO:0006839	mitochondrial transport	8/988	254/18722	0.961210524397917	0.972376748353025	ABLIM3/CPT1A/STAT3/LEPROT/PRKAA1/ATF2/SH3GLB1/HSPA1A	8
GO:0006081	cellular aldehyde metabolic process	1/988	60/18722	0.961543006516432	0.972527884732537	GLO1	1
GO:0042472	inner ear morphogenesis	2/988	96/18722	0.965458354867649	0.976165722662091	GATA2/FZD6	2
GO:0009116	nucleoside metabolic process	1/988	62/18722	0.96550728668423	0.976165722662091	NT5E	1
GO:0006520	cellular amino acid metabolic process	9/988	284/18722	0.966863755579578	0.977351145506893	IDO1/SERINC3/GLS/MRI1/DDAH2/PLOD2/ACAT1/ATP2B4/SLC16A2	9
GO:0045143	homologous chromosome segregation	1/988	63/18722	0.967333588975547	0.977640035129015	SUN1	1
GO:0009636	response to toxic substance	8/988	262/18722	0.969461909541942	0.979604653507095	NXN/CLIC2/AHR/MGST2/TP53INP1/CD36/SLC30A1/MAPK1	8
GO:1901617	organic hydroxy compound biosynthetic process	7/988	237/18722	0.969680072868541	0.979638749919683	P2RY1/SPTLC2/LBR/RAPGEF2/STARD4/PRKAA1/CYB5R3	7
GO:0061512	protein localization to cilium	1/988	65/18722	0.970701482531639	0.980297770952104	CCDC88A	1
GO:1902475	L-alpha-amino acid transmembrane transport	1/988	65/18722	0.970701482531639	0.980297770952104	ITGB1	1
GO:0006910	phagocytosis, recognition	2/988	100/18722	0.971243644199106	0.98047248916489	SCARB1/CD36	2
GO:0009062	fatty acid catabolic process	2/988	100/18722	0.971243644199106	0.98047248916489	CPT1A/ACAT1	2
GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	1/988	67/18722	0.97372246265731	0.982601390888227	CALCRL	1
GO:0009583	detection of light stimulus	1/988	67/18722	0.97372246265731	0.982601390888227	GNAQ	1
GO:0051966	regulation of synaptic transmission, glutamatergic	1/988	69/18722	0.9764322310817	0.98505388951707	MEF2C	1
GO:0098656	anion transmembrane transport	7/988	245/18722	0.976523678877426	0.98505388951707	LRRC8C/CLIC2/ITGB1/SLC12A2/GJA1/XPR1/CLCN3	7
GO:0007218	neuropeptide signaling pathway	2/988	106/18722	0.978205124708865	0.98656267751158	CPE/RAPGEF2	2
GO:0016579	protein deubiquitination	3/988	139/18722	0.979774921769965	0.987958311397504	ATXN3/CYLD/USP31	3
GO:0006323	DNA packaging	5/988	199/18722	0.981722786955227	0.989485900387194	ATRX/RSF1/KAT6A/UBN2/BAZ2A	5
GO:0030317	flagellated sperm motility	2/988	110/18722	0.981907294943935	0.989485900387194	ATP2B4/ASH1L	2
GO:0097722	sperm motility	2/988	110/18722	0.981907294943935	0.989485900387194	ATP2B4/ASH1L	2
GO:0051881	regulation of mitochondrial membrane potential	1/988	74/18722	0.982047282177143	0.989485900387194	KDR	1
GO:0006310	DNA recombination	9/988	305/18722	0.982221226043237	0.989485900387194	REV3L/TGFB1/SETX/ACTR2/RECQL/NIPBL/KMT5B/RIF1/INO80D	9
GO:0009123	nucleoside monophosphate metabolic process	1/988	76/18722	0.983899262138479	0.99088892016116	NT5E	1
GO:0045333	cellular respiration	6/988	230/18722	0.983987020679616	0.99088892016116	COX7A1/PIK3CA/RHOA/HIF1A/IFNAR1/PLEC	6
GO:0022900	electron transport chain	4/988	175/18722	0.984443764896935	0.991160970267725	IDO1/LOXL2/COX7A1/PLEC	4
GO:0022904	respiratory electron transport chain	2/988	114/18722	0.984995995663158	0.991529037135246	COX7A1/PLEC	2
GO:0046395	carboxylic acid catabolic process	6/988	236/18722	0.987026181368085	0.99338444020979	IDO1/GLS/DDAH2/CPT1A/ACAT1/ATP2B4	6
GO:0072527	pyrimidine-containing compound metabolic process	1/988	82/18722	0.988386550848441	0.994565136978011	MAPK1	1
GO:0016054	organic acid catabolic process	6/988	240/18722	0.988741689725331	0.994734063602455	IDO1/GLS/DDAH2/CPT1A/ACAT1/ATP2B4	6
GO:0044242	cellular lipid catabolic process	5/988	214/18722	0.98952030012875	0.995143724833029	ENPP2/SCARB1/MGST2/CPT1A/ACAT1	5
GO:0019730	antimicrobial humoral response	2/988	122/18722	0.989710899528029	0.995143724833029	HLA-E/HLA-A	2
GO:0072329	monocarboxylic acid catabolic process	2/988	122/18722	0.989710899528029	0.995143724833029	CPT1A/ACAT1	2
GO:0060294	cilium movement involved in cell motility	2/988	125/18722	0.991076305348637	0.996218807750706	ATP2B4/ASH1L	2
GO:0019646	aerobic electron transport chain	1/988	87/18722	0.991155195587817	0.996218807750706	COX7A1	1
GO:1901657	glycosyl compound metabolic process	1/988	88/18722	0.991624133970389	0.996501589037213	NT5E	1
GO:0007127	meiosis I	2/988	129/18722	0.992624582659854	0.997318286947067	CDC25B/SUN1	2
GO:0042773	ATP synthesis coupled electron transport	1/988	95/18722	0.99428016371776	0.998531057241477	COX7A1	1
GO:0042775	mitochondrial ATP synthesis coupled electron transport	1/988	95/18722	0.99428016371776	0.998531057241477	COX7A1	1
GO:0061982	meiosis I cell cycle process	2/988	135/18722	0.99446634525411	0.998531057241477	CDC25B/SUN1	2
GO:0043648	dicarboxylic acid metabolic process	1/988	96/18722	0.99458355117934	0.998531057241477	GLS	1
GO:0001539	cilium or flagellum-dependent cell motility	2/988	138/18722	0.995209805840087	0.998782257438606	ATP2B4/ASH1L	2
GO:0060285	cilium-dependent cell motility	2/988	138/18722	0.995209805840087	0.998782257438606	ATP2B4/ASH1L	2
GO:0044282	small molecule catabolic process	10/988	376/18722	0.995693873041183	0.998915260476112	IDO1/SCARF1/SCARB1/GLS/DDAH2/CPT1A/NUDT3/PTEN/ACAT1/ATP2B4	10
GO:0006119	oxidative phosphorylation	2/988	141/18722	0.995855027322915	0.998915260476112	COX7A1/RHOA	2
GO:0034308	primary alcohol metabolic process	1/988	102/18722	0.996094528377629	0.998915260476112	IGF1	1
GO:1990542	mitochondrial transmembrane transport	1/988	102/18722	0.996094528377629	0.998915260476112	CPT1A	1
GO:0140053	mitochondrial gene expression	1/988	108/18722	0.997184307128013	0.999738443983514	PRKAA1	1
GO:0006805	xenobiotic metabolic process	1/988	111/18722	0.997609308561736	0.999738443983514	AHR	1
GO:0120254	olefinic compound metabolic process	2/988	153/18722	0.997684812571316	0.999738443983514	ELOVL5/EGR1	2
GO:0009060	aerobic respiration	3/988	189/18722	0.997715832339538	0.999738443983514	COX7A1/RHOA/HIF1A	3
GO:0001578	microtubule bundle formation	1/988	113/18722	0.997856406250111	0.999738443983514	CCSER2	1
GO:0022613	ribonucleoprotein complex biogenesis	12/988	463/18722	0.998565028771458	0.999995328926053	DDX17/DICER1/PTEN/SETX/ADAR/CELF1/SF3B1/LUC7L3/RBM5/SCAF11/XPO1/PSIP1	12
GO:0003341	cilium movement	2/988	175/18722	0.99921475057404	0.999995328926053	ATP2B4/ASH1L	2
GO:0002181	cytoplasmic translation	1/988	148/18722	0.999682951323482	0.999995328926053	CNBP	1
GO:0009451	RNA modification	1/988	167/18722	0.999887831196513	0.999995328926053	ADAR	1
GO:0006399	tRNA metabolic process	1/988	179/18722	0.999941839935391	0.999995328926053	DICER1	1
GO:0016072	rRNA metabolic process	2/988	236/18722	0.999963424667286	0.999995328926053	DDX17/XRN1	2
GO:0034470	ncRNA processing	6/988	395/18722	0.999976635465334	0.999995328926053	SMAD1/DDX17/DICER1/STAT3/ADAR/SMAD2	6
GO:0042254	ribosome biogenesis	3/988	299/18722	0.999987175042733	0.999995328926053	DDX17/PTEN/XPO1	3
GO:0034660	ncRNA metabolic process	8/988	485/18722	0.99999162285186	0.999995328926053	SMAD1/DDX17/DICER1/STAT3/ADAR/RC3H1/SMAD2/XRN1	8
GO:0006364	rRNA processing	1/988	225/18722	0.999995328926053	0.999995328926053	DDX17	1