ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0003779	actin binding	33/393	440/18367	4.47057502572473e-10	2.8924620416439e-07	LRRK2/LCP1/GMFG/MYO1F/AIF1/TMSB4X/WIPF1/LSP1/CORO1A/MARCKS/FMNL1/MSRB1/WAS/S100A4/CNN2/PPP1R18/IQGAP1/CXCR4/MSN/ACTR2/COTL1/CAP1/ARPC3/VASP/ARPC5/HCLS1/TPM3/SSH2/CAPZA1/ACTR3/ACTN1/MYH9/TMOD3	33
GO:0140375	immune receptor activity	17/393	144/18367	1.27148035530628e-08	4.11323894941582e-06	CXCR2/FPR1/C5AR1/FCER1G/LILRB3/CSF2RB/FPR2/CXCR1/CSF3R/IL6R/IL2RG/IL17RA/LILRB2/CXCR4/CD44/IFNGR2/IFNAR1	17
GO:0050786	RAGE receptor binding	5/393	10/18367	1.00872809203216e-06	0.000217549025181602	S100A8/S100A12/S100A9/FPR1/S100A4	5
GO:0051015	actin filament binding	17/393	217/18367	4.59276620864694e-06	0.000742879934248643	LCP1/MYO1F/AIF1/CORO1A/MARCKS/FMNL1/IQGAP1/ACTR2/COTL1/ARPC3/ARPC5/HCLS1/TPM3/CAPZA1/ACTR3/ACTN1/MYH9	17
GO:0004896	cytokine receptor activity	11/393	97/18367	7.16437572590449e-06	0.000927070218932041	CXCR2/CSF2RB/CXCR1/CSF3R/IL6R/IL2RG/IL17RA/CXCR4/CD44/IFNGR2/IFNAR1	11
GO:0031720	haptoglobin binding	4/393	10/18367	3.91440303797343e-05	0.00422103127594802	HBA2/HBA1/HBB/HBG2	4
GO:0019864	IgG binding	4/393	11/18367	6.04738496469794e-05	0.00558951153165652	FCGR3B/FCGR2A/FCER1G/FCGRT	4
GO:0005126	cytokine receptor binding	17/393	271/18367	8.01977946275044e-05	0.00588843587445108	CXCL8/OSM/LRG1/LTB/IL6R/IL1B/CFLAR/SDCBP/TNFSF13B/PYCARD/TNFSF10/CKLF/JAK1/USP15/STAT3/TGFBR2/BID	17
GO:0035325	Toll-like receptor binding	4/393	12/18367	8.91808220982251e-05	0.00588843587445108	S100A8/S100A9/TLR1/LY96	4
GO:0016209	antioxidant activity	9/393	86/18367	9.22482386071008e-05	0.00588843587445108	S100A9/SOD2/PTGS2/ALOX5AP/HBA2/HBA1/HBB/HBG2/CAT	9
GO:0004601	peroxidase activity	7/393	51/18367	0.000100112511003032	0.00588843587445108	PTGS2/ALOX5AP/HBA2/HBA1/HBB/HBG2/CAT	7
GO:0048306	calcium-dependent protein binding	9/393	88/18367	0.000110395031071312	0.00595213209192825	S100A8/S100A12/S100A9/CD177/S100A4/S100A6/S100A11/CPNE3/DDX5	9
GO:0043177	organic acid binding	11/393	135/18367	0.000156335647971335	0.00663432105822242	S100A8/S100A9/ALOX5AP/HBA2/HBA1/HBB/GLUL/EGLN1/HBG2/STX3/IGF2R	11
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/393	55/18367	0.000163066458137858	0.00663432105822242	PTGS2/ALOX5AP/HBA2/HBA1/HBB/HBG2/CAT	7
GO:0044389	ubiquitin-like protein ligase binding	18/393	316/18367	0.00016904064507371	0.00663432105822242	LYN/LAPTM5/TRIB1/TXNIP/CEBPB/ARRB2/CXCR4/TNFRSF1B/JAK1/UBE2D1/RALB/PRKAR1A/BID/UBE2B/YWHAZ/HIF1A/HSPA1A/CUL3	18
GO:0005344	oxygen carrier activity	4/393	14/18367	0.00017431755485283	0.00663432105822242	HBA2/HBA1/HBB/HBG2	4
GO:0036041	long-chain fatty acid binding	4/393	14/18367	0.00017431755485283	0.00663432105822242	S100A8/S100A9/ALOX5AP/STX3	4
GO:0038187	pattern recognition receptor activity	5/393	26/18367	0.000198501517755859	0.00713502677711339	PGLYRP1/CLEC4E/LY96/CLEC7A/FCN1	5
GO:0031625	ubiquitin protein ligase binding	17/393	297/18367	0.000240768992785293	0.00819881780695182	LYN/LAPTM5/TRIB1/TXNIP/ARRB2/CXCR4/TNFRSF1B/JAK1/UBE2D1/RALB/PRKAR1A/BID/UBE2B/YWHAZ/HIF1A/HSPA1A/CUL3	17
GO:0017124	SH3 domain binding	10/393	130/18367	0.000489700090330277	0.0158417979221845	NCF1/LYN/WIPF1/WAS/CYBA/VASP/HCLS1/PLSCR1/PTPN6/SH3BGRL	10
GO:0042277	peptide binding	17/393	321/18367	0.000587629392539006	0.0181045817606065	SORL1/FPR2/HLA-B/HLA-C/TLR1/HLA-E/ITGB2/ITM2B/HLA-A/LILRB2/PICALM/NUP214/KPNA4/NPEPPS/MME/PPP3CA/CAT	17
GO:0051213	dioxygenase activity	8/393	92/18367	0.000795889557900681	0.0221224227804235	PTGS2/ALOX5AP/ALOX5/KDM6B/EGLN1/JMJD1C/KDM5A/TET2	8
GO:0019955	cytokine binding	10/393	139/18367	0.000826742159590122	0.0221224227804235	CXCR2/CXCR1/ZFP36/CSF3R/IL6R/IL2RG/CXCR4/TNFRSF1B/TGFBR2/IFNAR1	10
GO:0020037	heme binding	10/393	139/18367	0.000826742159590122	0.0221224227804235	PTGS2/STEAP4/CYP4F3/HBA2/CYBA/HBA1/HBB/HBG2/BACH1/CAT	10
GO:0045296	cadherin binding	17/393	332/18367	0.000854807680850986	0.0221224227804235	CNN2/EFHD2/IQGAP1/TAGLN2/S100A11/LRRFIP1/NUMB/VASP/PICALM/CAPZA1/YWHAZ/DDX3X/HSPA1A/MYH9/PAK2/SH3GLB1/TMOD3	17
GO:0140104	molecular carrier activity	7/393	73/18367	0.000942339922920395	0.0234497665434421	HBA2/XPO6/HBA1/HBB/HBG2/NUP214/KPNA4	7
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/393	10/18367	0.00104312221573568	0.0241035740564637	NCF1/NCF2/CYBA	3
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/393	10/18367	0.00104312221573568	0.0241035740564637	NCF1/NCF2/NCF4	3
GO:0005178	integrin binding	10/393	144/18367	0.00108438671826567	0.0241930416109616	LCP1/JAML/LYN/CD177/ICAM3/ITGAX/ITGB2/IL1B/ACTN1/MYH9	10
GO:0019865	immunoglobulin binding	4/393	23/18367	0.00132415992913694	0.0283168947274821	FCGR3B/FCGR2A/FCER1G/FCGRT	4
GO:0019825	oxygen binding	5/393	39/18367	0.00138341240237607	0.0283168947274821	SOD2/HBA2/HBA1/HBB/HBG2	5
GO:0046906	tetrapyrrole binding	10/393	149/18367	0.00140426229620349	0.0283168947274821	PTGS2/STEAP4/CYP4F3/HBA2/CYBA/HBA1/HBB/HBG2/BACH1/CAT	10
GO:0031267	small GTPase binding	14/393	259/18367	0.0014442929304589	0.0283168947274821	SORL1/LRRK2/NCF2/FMNL1/WAS/ARHGDIB/RASSF5/XPO6/IQGAP1/PICALM/RAB11FIP1/CDC42SE1/PAK2/PAK1	14
GO:0019887	protein kinase regulator activity	12/393	204/18367	0.00153008301687431	0.0285150042584816	GMFG/RAC2/TRIB1/CDKN2D/IQGAP1/STK4/DAZAP2/CCNL1/PRKAR1A/RICTOR/DDX3X/PAK2	12
GO:0019957	C-C chemokine binding	4/393	24/18367	0.00156242054563829	0.0285150042584816	CXCR2/CXCR1/ZFP36/CXCR4	4
GO:0051020	GTPase binding	15/393	291/18367	0.0015866153837795	0.0285150042584816	SORL1/LRRK2/LCP1/NCF2/FMNL1/WAS/ARHGDIB/RASSF5/XPO6/IQGAP1/PICALM/RAB11FIP1/CDC42SE1/PAK2/PAK1	15
GO:0005200	structural constituent of cytoskeleton	8/393	103/18367	0.00165986294886612	0.029025171024767	TUBA1A/ACTB/VIM/MSN/ACTR2/ARPC3/ARPC5/ACTR3	8
GO:0004875	complement receptor activity	3/393	12/18367	0.00185242686332585	0.0315400047518901	FPR1/C5AR1/FPR2	3
GO:0008198	ferrous iron binding	4/393	26/18367	0.00212538781897407	0.0352596389455441	FTH1/FTL/EGLN1/TET2	4
GO:0002020	protease binding	9/393	135/18367	0.00251301195745139	0.0405818644354294	SELL/CD177/SERPINA1/MBP/CFLAR/PTEN/PYCARD/CARD16/FLOT2	9
GO:0033218	amide binding	18/393	400/18367	0.00257164828725287	0.0405818644354294	SORL1/FPR2/HLA-B/HLA-C/TLR1/HLA-E/ITGB2/ITM2B/HLA-A/LILRB2/PICALM/NQO2/NUP214/KPNA4/NPEPPS/MME/PPP3CA/CAT	18
GO:0044548	S100 protein binding	3/393	14/18367	0.00296902770342299	0.0457371648598732	S100A6/IQGAP1/S100A11	3
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/393	15/18367	0.00365285839048731	0.0549627762475649	NCF1/NCF2/CYBA	3
GO:0032813	tumor necrosis factor receptor superfamily binding	5/393	49/18367	0.00384938067678167	0.0553455399528387	LTB/CFLAR/TNFSF13B/TNFSF10/BID	5
GO:0043539	protein serine/threonine kinase activator activity	5/393	49/18367	0.00384938067678167	0.0553455399528387	IQGAP1/STK4/DAZAP2/RICTOR/DDX3X	5
GO:0004721	phosphoprotein phosphatase activity	10/393	174/18367	0.00434162562000109	0.0609160953362167	PTPRC/LRRK2/DUSP1/PTPRE/PPP2R5A/PTEN/CPPED1/SSH2/PTPN6/PPP3CA	10
GO:0005523	tropomyosin binding	3/393	16/18367	0.00442512593632486	0.0609160953362167	S100A6/PYCARD/TMOD3	3
GO:0019207	kinase regulator activity	12/393	233/18367	0.00454182131185259	0.0609257042963663	GMFG/RAC2/TRIB1/CDKN2D/IQGAP1/STK4/DAZAP2/CCNL1/PRKAR1A/RICTOR/DDX3X/PAK2	12
GO:0031406	carboxylic acid binding	10/393	176/18367	0.0047034234015185	0.0609257042963663	S100A8/S100A9/ALOX5AP/PYGL/FCN1/GLUL/EGLN1/STX3/IGF2R/ST8SIA4	10
GO:0033293	monocarboxylic acid binding	6/393	73/18367	0.00470832336138843	0.0609257042963663	S100A8/S100A9/ALOX5AP/PYGL/STX3/IGF2R	6
GO:0003725	double-stranded RNA binding	6/393	74/18367	0.00503358654040877	0.062217406468401	VIM/MSN/LRRFIP1/ACTN1/DICER1/ADAR	6
GO:0019956	chemokine binding	4/393	33/18367	0.0051724666289711	0.062217406468401	CXCR2/CXCR1/ZFP36/CXCR4	4
GO:0005506	iron ion binding	9/393	151/18367	0.00527351771601584	0.062217406468401	CYP4F3/FTH1/FTL/ALOX5/HBA2/HBA1/FBXL5/EGLN1/TET2	9
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/393	17/18367	0.00528896036439267	0.062217406468401	PTPRC/PTPRE/PTPN6	3
GO:0019198	transmembrane receptor protein phosphatase activity	3/393	17/18367	0.00528896036439267	0.062217406468401	PTPRC/PTPRE/PTPN6	3
GO:0030246	carbohydrate binding	13/393	271/18367	0.00579537811500527	0.0669573150072931	SELL/MGAM/SLC2A3/CD93/PYGL/CLEC4E/CLEC7A/FCN1/EGLN1/CD302/CLEC2B/IGF2R/TALDO1	13
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/393	18/18367	0.00624716536921614	0.0709108069102253	DAZAP2/TGFBR2/MAPK1	3
GO:0042605	peptide antigen binding	4/393	36/18367	0.00708151738803935	0.0789955474148527	HLA-B/HLA-C/HLA-E/HLA-A	4
GO:0044325	transmembrane transporter binding	8/393	133/18367	0.00789369239605271	0.0865630335634932	LRRK2/LYN/TSPO/PYCARD/ACTN1/YWHAZ/GRINA/USP10	8
GO:0001540	amyloid-beta binding	6/393	84/18367	0.00925206082428848	0.0997352651014127	SORL1/FPR2/ITGB2/ITM2B/LILRB2/PICALM	6
GO:0005504	fatty acid binding	4/393	39/18367	0.00940543381195047	0.0997352651014127	S100A8/S100A9/ALOX5AP/STX3	4
GO:0001848	complement binding	3/393	21/18367	0.00971147094495982	0.0997352651014127	C5AR1/CD93/ITGB2	3
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/393	21/18367	0.00971147094495982	0.0997352651014127	MBOAT7/LPGAT1/LPCAT2	3
GO:0051219	phosphoprotein binding	6/393	88/18367	0.0114941130067399	0.116198298677511	LYN/HCK/FGR/IGF2R/PTPN6/MAPK1	6
GO:0016922	nuclear receptor binding	8/393	144/18367	0.0124060831544584	0.116468221202437	PRKCB/CEBPB/JMJD1C/STAT3/NCOA1/TAF7/HIF1A/DDX5	8
GO:0016493	C-C chemokine receptor activity	3/393	23/18367	0.0125309618499082	0.116468221202437	CXCR2/CXCR1/CXCR4	3
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/393	23/18367	0.0125309618499082	0.116468221202437	PTGS2/ALOX5AP/ALOX5	3
GO:0042171	lysophosphatidic acid acyltransferase activity	3/393	23/18367	0.0125309618499082	0.116468221202437	MBOAT7/LPGAT1/LPCAT2	3
GO:0071617	lysophospholipid acyltransferase activity	3/393	23/18367	0.0125309618499082	0.116468221202437	MBOAT7/LPGAT1/LPCAT2	3
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	13/393	299/18367	0.0126008894654878	0.116468221202437	SPI1/ACTB/FOS/PRKCB/CEBPB/JMJD1C/HCLS1/STAT3/NCOA1/TAF7/HIF1A/DDX5/NFE2L2	13
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/393	24/18367	0.0140978963219468	0.12836326662829	PTGS2/ALOX5AP/ALOX5	3
GO:0001784	phosphotyrosine residue binding	4/393	44/18367	0.0142846293620354	0.12836326662829	HCK/FGR/PTPN6/MAPK1	4
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/393	45/18367	0.0154203016150011	0.132516820038258	LYN/HCK/FGR/JAK1	4
GO:0005160	transforming growth factor beta receptor binding	3/393	25/18367	0.0157709353059442	0.132516820038258	LRG1/USP15/TGFBR2	3
GO:0035035	histone acetyltransferase binding	3/393	25/18367	0.0157709353059442	0.132516820038258	CEBPB/EGR1/TAF7	3
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/393	25/18367	0.0157709353059442	0.132516820038258	ZFP36/ZFP36L1/ZFP36L2	3
GO:0051019	mitogen-activated protein kinase binding	3/393	25/18367	0.0157709353059442	0.132516820038258	DUSP1/ARRB2/IQGAP1	3
GO:0001637	G protein-coupled chemoattractant receptor activity	3/393	26/18367	0.0175507893259838	0.139626032252974	CXCR2/CXCR1/CXCR4	3
GO:0004950	chemokine receptor activity	3/393	26/18367	0.0175507893259838	0.139626032252974	CXCR2/CXCR1/CXCR4	3
GO:0048029	monosaccharide binding	5/393	71/18367	0.0179803546661615	0.139626032252974	SLC2A3/PYGL/EGLN1/IGF2R/TALDO1	5
GO:0030695	GTPase regulator activity	18/393	488/18367	0.0182254164396669	0.139626032252974	RGS2/LRRK2/RGS18/GPSM3/ARHGAP9/DENND3/SMAP2/WAS/ARHGDIB/ARHGAP15/CYTH4/PREX1/IQGAP1/ARHGAP26/ACAP2/SOS2/CDC42SE1/DOCK5	18
GO:0060589	nucleoside-triphosphatase regulator activity	18/393	488/18367	0.0182254164396669	0.139626032252974	RGS2/LRRK2/RGS18/GPSM3/ARHGAP9/DENND3/SMAP2/WAS/ARHGDIB/ARHGAP15/CYTH4/PREX1/IQGAP1/ARHGAP26/ACAP2/SOS2/CDC42SE1/DOCK5	18
GO:0005522	profilin binding	2/393	10/18367	0.0183434509142238	0.139626032252974	WIPF1/VASP	2
GO:0043208	glycosphingolipid binding	2/393	10/18367	0.0183434509142238	0.139626032252974	SELL/LYN	2
GO:0047844	deoxycytidine deaminase activity	2/393	10/18367	0.0183434509142238	0.139626032252974	CDA/APOBEC3A	2
GO:0004722	protein serine/threonine phosphatase activity	6/393	98/18367	0.018723980233415	0.14086529315139	LRRK2/DUSP1/PTEN/CPPED1/SSH2/PPP3CA	6
GO:0106306	protein serine phosphatase activity	5/393	73/18367	0.0200443145907654	0.147371267502559	DUSP1/PTEN/CPPED1/SSH2/PPP3CA	5
GO:0106307	protein threonine phosphatase activity	5/393	73/18367	0.0200443145907654	0.147371267502559	DUSP1/PTEN/CPPED1/SSH2/PPP3CA	5
GO:0030295	protein kinase activator activity	6/393	101/18367	0.0213881716653014	0.147425642386573	IQGAP1/STK4/DAZAP2/RICTOR/DDX3X/PAK2	6
GO:0051861	glycolipid binding	3/393	28/18367	0.0214327716647452	0.147425642386573	SELL/LYN/CLEC4E	3
GO:0005049	nuclear export signal receptor activity	2/393	11/18367	0.022106081038936	0.147425642386573	XPO6/NUP214	2
GO:0005536	glucose binding	2/393	11/18367	0.022106081038936	0.147425642386573	SLC2A3/PYGL	2
GO:0008199	ferric iron binding	2/393	11/18367	0.022106081038936	0.147425642386573	FTH1/FTL	2
GO:0042608	T cell receptor binding	2/393	11/18367	0.022106081038936	0.147425642386573	HLA-E/HLA-A	2
GO:0051400	BH domain binding	2/393	11/18367	0.022106081038936	0.147425642386573	BCL2A1/MCL1	2
GO:0099186	structural constituent of postsynapse	2/393	11/18367	0.022106081038936	0.147425642386573	ACTB/ACTN1	2
GO:0140036	ubiquitin-dependent protein binding	2/393	11/18367	0.022106081038936	0.147425642386573	LAPTM5/USP15	2
GO:0004725	protein tyrosine phosphatase activity	6/393	102/18367	0.0223303136845195	0.147425642386573	PTPRC/DUSP1/PTPRE/PTEN/SSH2/PTPN6	6
GO:0140297	DNA-binding transcription factor binding	15/393	394/18367	0.0231091966951928	0.150765995297132	SPI1/ACTB/FOS/PRKCB/CEBPB/JMJD1C/HCLS1/STAT3/YWHAZ/NCOA1/TAF7/HIF1A/DDX5/NBN/NFE2L2	15
GO:0032452	histone demethylase activity	3/393	29/18367	0.0235353408423653	0.150765995297132	KDM6B/JMJD1C/KDM5A	3
GO:0140457	protein demethylase activity	3/393	29/18367	0.0235353408423653	0.150765995297132	KDM6B/JMJD1C/KDM5A	3
GO:0004126	cytidine deaminase activity	2/393	12/18367	0.026156811874058	0.162725550793418	CDA/APOBEC3A	2
GO:0005095	GTPase inhibitor activity	2/393	12/18367	0.026156811874058	0.162725550793418	IQGAP1/CDC42SE1	2
GO:0032396	inhibitory MHC class I receptor activity	2/393	12/18367	0.026156811874058	0.162725550793418	LILRB3/LILRB2	2
GO:0019209	kinase activator activity	6/393	107/18367	0.0274606049484875	0.164422110049796	IQGAP1/STK4/DAZAP2/RICTOR/DDX3X/PAK2	6
GO:0000146	microfilament motor activity	3/393	31/18367	0.0280634247218615	0.164422110049796	MYO1F/MYH9/MYL6	3
GO:0005164	tumor necrosis factor receptor binding	3/393	31/18367	0.0280634247218615	0.164422110049796	LTB/TNFSF13B/TNFSF10	3
GO:0016411	acylglycerol O-acyltransferase activity	3/393	31/18367	0.0280634247218615	0.164422110049796	MBOAT7/LPGAT1/LPCAT2	3
GO:0043015	gamma-tubulin binding	3/393	31/18367	0.0280634247218615	0.164422110049796	LYN/DDX3X/PAK1	3
GO:0140142	nucleocytoplasmic carrier activity	3/393	31/18367	0.0280634247218615	0.164422110049796	XPO6/NUP214/KPNA4	3
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4/393	54/18367	0.0282084300085431	0.164422110049796	KDM6B/EGLN1/KDM5A/TET2	4
GO:0005516	calmodulin binding	9/393	201/18367	0.0293937601246881	0.166519533656876	RGS2/MYO1F/MARCKS/MBP/CNN2/IQGAP1/DDX5/MYH9/PPP3CA	9
GO:0003924	GTPase activity	13/393	337/18367	0.0301166318520424	0.166519533656876	RGS2/LRRK2/RGS18/MX2/RAC2/TUBA1A/ARHGDIB/RAB27A/RALB/RHOG/DDX3X/RAB8B/RAB7A	13
GO:0034236	protein kinase A catalytic subunit binding	2/393	13/18367	0.0304816574433385	0.166519533656876	PJA2/PRKAR1A	2
GO:0061783	peptidoglycan muralytic activity	2/393	13/18367	0.0304816574433385	0.166519533656876	PGLYRP1/LYZ	2
GO:0072542	protein phosphatase activator activity	2/393	13/18367	0.0304816574433385	0.166519533656876	PPP2R5A/PPP1R15A	2
GO:0140035	ubiquitination-like modification-dependent protein binding	2/393	13/18367	0.0304816574433385	0.166519533656876	LAPTM5/USP15	2
GO:0071889	14-3-3 protein binding	3/393	32/18367	0.0304883713258066	0.166519533656876	ZFP36/ARRB2/ZFP36L1	3
GO:0000149	SNARE binding	6/393	110/18367	0.0308846121156493	0.166519533656876	LRRK2/STX3/TNFAIP2/PICALM/STX7/STXBP3	6
GO:0008047	enzyme activator activity	6/393	110/18367	0.0308846121156493	0.166519533656876	NCF1/GMFG/NCF2/ALOX5AP/NCF4/CFLAR	6
GO:0045309	protein phosphorylated amino acid binding	4/393	56/18367	0.0317010014707018	0.169145627646181	HCK/FGR/PTPN6/MAPK1	4
GO:0019838	growth factor binding	7/393	141/18367	0.0321559693979603	0.169145627646181	DUSP1/IL6R/IL2RG/SDCBP/IGF2R/TGFBR2/NRDC	7
GO:0070851	growth factor receptor binding	7/393	141/18367	0.0321559693979603	0.169145627646181	LYN/IL6R/IL1B/PTEN/SDCBP/PYCARD/PLSCR1	7
GO:0019239	deaminase activity	3/393	33/18367	0.0330199617954901	0.172289639368404	CDA/APOBEC3A/ADAR	3
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	16/393	450/18367	0.0335363895036293	0.173584352070785	LITAF/JUNB/SPI1/FOS/CEBPB/KLF6/EGR1/IRF1/PLSCR1/STAT3/HIF1A/CREBRF/BACH1/CEBPD/FOSL2/NFE2L2	16
GO:0035259	glucocorticoid receptor binding	2/393	14/18367	0.0350670957333244	0.179244022364307	CEBPB/STAT3	2
GO:0016791	phosphatase activity	11/393	275/18367	0.0351839116541994	0.179244022364307	PTPRC/LRRK2/ALPL/DUSP1/PTPRE/PPP2R5A/PTEN/CPPED1/SSH2/PTPN6/PPP3CA	11
GO:0001216	DNA-binding transcription activator activity	16/393	456/18367	0.0371338527208598	0.187700021174971	LITAF/JUNB/SPI1/FOS/CEBPB/KLF6/EGR1/IRF1/PLSCR1/STAT3/HIF1A/CREBRF/BACH1/CEBPD/FOSL2/NFE2L2	16
GO:0001846	opsonin binding	2/393	15/18367	0.0399000553245302	0.19410026913512	CD93/ITGB2	2
GO:0005041	low-density lipoprotein particle receptor activity	2/393	15/18367	0.0399000553245302	0.19410026913512	SORL1/LRP10	2
GO:0005161	platelet-derived growth factor receptor binding	2/393	15/18367	0.0399000553245302	0.19410026913512	LYN/PTEN	2
GO:0005545	1-phosphatidylinositol binding	2/393	15/18367	0.0399000553245302	0.19410026913512	SNX10/PICALM	2
GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	2/393	15/18367	0.0399000553245302	0.19410026913512	CFLAR/PYCARD	2
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	3/393	36/18367	0.0412475493937786	0.196229150424814	CDA/APOBEC3A/ADAR	3
GO:0043394	proteoglycan binding	3/393	36/18367	0.0412475493937786	0.196229150424814	PTPRC/CTSS/SDCBP	3
GO:0061631	ubiquitin conjugating enzyme activity	3/393	36/18367	0.0412475493937786	0.196229150424814	UBE2D1/UBE2D3/UBE2B	3
GO:0005521	lamin binding	2/393	16/18367	0.044967902379988	0.212366663064615	LBR/BNIP3L	2
GO:0016722	oxidoreductase activity, acting on metal ions	2/393	17/18367	0.0502584279820674	0.229660355204159	STEAP4/FTH1	2
GO:0032393	MHC class I receptor activity	2/393	17/18367	0.0502584279820674	0.229660355204159	LILRB3/LILRB2	2
GO:0043024	ribosomal small subunit binding	2/393	17/18367	0.0502584279820674	0.229660355204159	EIF1/DDX3X	2
GO:0032451	demethylase activity	3/393	39/18367	0.0504045910958123	0.229660355204159	KDM6B/JMJD1C/KDM5A	3
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/393	39/18367	0.0504045910958123	0.229660355204159	UBE2D1/UBE2D3/UBE2B	3
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	6/393	125/18367	0.052123750961597	0.235832635469603	VNN2/PGLYRP1/CDA/APOBEC3A/ADAR/CAT	6
GO:0003925	G protein activity	3/393	40/18367	0.0536581105227027	0.239426189711646	RAB27A/RALB/RAB7A	3
GO:0042287	MHC protein binding	3/393	40/18367	0.0536581105227027	0.239426189711646	HLA-E/LILRB2/CLEC7A	3
GO:0030228	lipoprotein particle receptor activity	2/393	18/18367	0.0557598358086738	0.24376090383927	SORL1/LRP10	2
GO:0098641	cadherin binding involved in cell-cell adhesion	2/393	18/18367	0.0557598358086738	0.24376090383927	S100A11/TMOD3	2
GO:0098918	structural constituent of synapse	2/393	18/18367	0.0557598358086738	0.24376090383927	ACTB/ACTN1	2
GO:0140030	modification-dependent protein binding	7/393	160/18367	0.0567126747577374	0.246262419921182	LYN/LAPTM5/USP15/PTPN6/TAF7/KDM5A/PHIP	7
GO:0019902	phosphatase binding	8/393	196/18367	0.06043328722953	0.260668912250039	PPP1R18/LILRB2/IQGAP1/BOD1L1/JAK1/STAT3/PPP1R15A/MAPK1	8
GO:0004860	protein kinase inhibitor activity	4/393	70/18367	0.0629653828030522	0.269792070685926	GMFG/TRIB1/CDKN2D/PRKAR1A	4
GO:0005125	cytokine activity	9/393	235/18367	0.0665673218572098	0.281132370386818	NAMPT/CXCL8/CMTM2/OSM/LTB/IL1B/TNFSF13B/TNFSF10/CKLF	9
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/393	20/18367	0.0673501041884959	0.281132370386818	FOS/CEBPB	2
GO:0019211	phosphatase activator activity	2/393	20/18367	0.0673501041884959	0.281132370386818	PPP2R5A/PPP1R15A	2
GO:0042288	MHC class I protein binding	2/393	20/18367	0.0673501041884959	0.281132370386818	HLA-E/LILRB2	2
GO:0042379	chemokine receptor binding	4/393	72/18367	0.0683955944712499	0.28366634373653	CXCL8/CKLF/JAK1/STAT3	4
GO:0031490	chromatin DNA binding	5/393	103/18367	0.0702589519309967	0.289538483435381	BCL6/ACTB/KDM6B/JMJD1C/STAT3	5
GO:0005096	GTPase activator activity	15/393	462/18367	0.0728436226035303	0.29761803546792	RGS2/LRRK2/RGS18/ARHGAP9/DENND3/SMAP2/ARHGDIB/ARHGAP15/CYTH4/PREX1/IQGAP1/ARHGAP26/ACAP2/SOS2/DOCK5	15
GO:0005123	death receptor binding	2/393	21/18367	0.0734173287404471	0.29761803546792	CFLAR/BID	2
GO:0017022	myosin binding	4/393	74/18367	0.0740595111442583	0.29761803546792	CORO1A/CXCR4/RAB27A/PYCARD	4
GO:0019210	kinase inhibitor activity	4/393	74/18367	0.0740595111442583	0.29761803546792	GMFG/TRIB1/CDKN2D/PRKAR1A	4
GO:0019003	GDP binding	4/393	75/18367	0.0769779315391889	0.307436553739847	RAB27A/RALB/RAB8B/RAB7A	4
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/393	47/18367	0.0791003910668901	0.31162522432817	DUSP1/PTEN/SSH2	3
GO:0017075	syntaxin-1 binding	2/393	22/18367	0.0796521411067284	0.31162522432817	LRRK2/STXBP3	2
GO:0033691	sialic acid binding	2/393	22/18367	0.0796521411067284	0.31162522432817	FCN1/ST8SIA4	2
GO:0001618	virus receptor activity	4/393	76/18367	0.0799533033052184	0.31162522432817	CXCR4/PLSCR1/CD55/HSPA1A	4
GO:0038024	cargo receptor activity	4/393	77/18367	0.0829850720596809	0.319591319182224	SORL1/FPR2/ITGB2/LRP10	4
GO:0140272	exogenous protein binding	4/393	77/18367	0.0829850720596809	0.319591319182224	CXCR4/PLSCR1/CD55/HSPA1A	4
GO:0070412	R-SMAD binding	2/393	23/18367	0.0860446343692827	0.329413481875301	FOS/DDX5	2
GO:0019199	transmembrane receptor protein kinase activity	6/393	143/18367	0.0870625997573705	0.330590598494581	LYN/HCK/FGR/JAK1/IGF2R/TGFBR2	6
GO:0047485	protein N-terminus binding	5/393	110/18367	0.0873740221678104	0.330590598494581	ALOX5AP/SDCBP/NCOA1/HSPA1A/NBN	5
GO:0046332	SMAD binding	4/393	79/18367	0.0892154431557581	0.335053562026371	FOS/USP15/TGFBR2/DDX5	4
GO:0016746	acyltransferase activity	9/393	250/18367	0.0895892832002507	0.335053562026371	QPCT/MBOAT7/ELOVL5/SAT1/ZDHHC18/LPGAT1/LPCAT2/GLUL/NCOA1	9
GO:0005048	signal sequence binding	3/393	50/18367	0.0913410752507788	0.339641814294563	NUP214/KPNA4/CAT	3
GO:0001965	G-protein alpha-subunit binding	2/393	24/18367	0.0925852469190405	0.342300884323538	RGS2/IGF2R	2
GO:0051018	protein kinase A binding	3/393	51/18367	0.0955861529834968	0.351387732842741	LRRK2/PJA2/PRKAR1A	3
GO:0043021	ribonucleoprotein complex binding	6/393	149/18367	0.100995579787191	0.369175932894421	NEAT1/EIF1/RICTOR/DDX3X/DDX5/CPEB4	6
GO:0001664	G protein-coupled receptor binding	10/393	295/18367	0.103032260631718	0.371757995461575	CXCL8/PROK2/FPR1/ARRB2/SDCBP/FCN1/CKLF/JAK1/STAT3/HSPA1A	10
GO:0019903	protein phosphatase binding	6/393	150/18367	0.103425717439078	0.371757995461575	LILRB2/IQGAP1/BOD1L1/JAK1/STAT3/PPP1R15A	6
GO:0140677	molecular function activator activity	6/393	150/18367	0.103425717439078	0.371757995461575	NCF1/GMFG/NCF2/ALOX5AP/NCF4/CFLAR	6
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	8/393	222/18367	0.105037270115372	0.375027536751103	MBOAT7/ELOVL5/SAT1/ZDHHC18/LPGAT1/LPCAT2/GLUL/NCOA1	8
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/393	26/18367	0.106074249189261	0.375027536751103	ZDHHC18/GLUL	2
GO:0019707	protein-cysteine S-acyltransferase activity	2/393	26/18367	0.106074249189261	0.375027536751103	ZDHHC18/GLUL	2
GO:0008374	O-acyltransferase activity	3/393	54/18367	0.108788567683726	0.381436671615857	MBOAT7/LPGAT1/LPCAT2	3
GO:0015631	tubulin binding	12/393	375/18367	0.109066127123545	0.381436671615857	S100A8/S100A9/RGS2/LRRK2/LYN/MX2/AGTPBP1/DDX3X/NIN/CEP350/PAK1/KATNBL1	12
GO:0001653	peptide receptor activity	6/393	153/18367	0.110897707574358	0.383926474118652	CXCR2/FPR1/FPR2/CXCR1/CXCR4/OGFRL1	6
GO:0004197	cysteine-type endopeptidase activity	5/393	119/18367	0.112259599420303	0.383926474118652	CTSS/CFLAR/PYCARD/USP15/USP10	5
GO:0004709	MAP kinase kinase kinase activity	2/393	27/18367	0.113005151995197	0.383926474118652	LRRK2/MAP3K2	2
GO:0008139	nuclear localization sequence binding	2/393	27/18367	0.113005151995197	0.383926474118652	NUP214/KPNA4	2
GO:0035255	ionotropic glutamate receptor binding	2/393	27/18367	0.113005151995197	0.383926474118652	PTEN/FLOT2	2
GO:0005080	protein kinase C binding	3/393	55/18367	0.113338418171039	0.383926474118652	PLEK/MARCKS/PRKCB	3
GO:0030374	nuclear receptor coactivator activity	3/393	56/18367	0.117959404022002	0.394273199338306	PRKCB/ACTN1/NCOA1	3
GO:0016651	oxidoreductase activity, acting on NAD(P)H	4/393	88/18367	0.119872121973081	0.394273199338306	NCF1/NCF2/CYBA/NQO2	4
GO:0003785	actin monomer binding	2/393	28/18367	0.120049181251385	0.394273199338306	TMSB4X/CORO1A	2
GO:0003953	NAD+ nucleosidase activity	2/393	28/18367	0.120049181251385	0.394273199338306	TLR1/PIK3AP1	2
GO:0046875	ephrin receptor binding	2/393	28/18367	0.120049181251385	0.394273199338306	LYN/SDCBP	2
GO:0050681	androgen receptor binding	2/393	28/18367	0.120049181251385	0.394273199338306	PRKCB/DDX5	2
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/393	29/18367	0.127198354615016	0.412160289588742	NCF1/PLEK	2
GO:0046625	sphingolipid binding	2/393	29/18367	0.127198354615016	0.412160289588742	SELL/LYN	2
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/393	124/18367	0.127406581016613	0.412160289588742	LYN/HCK/FGR/JAK1/IGF2R	5
GO:0036002	pre-mRNA binding	3/393	59/18367	0.132228587663204	0.425631324468123	CELF2/DDX5/SF1	3
GO:0009055	electron transfer activity	5/393	126/18367	0.133714921841527	0.426401474260419	NCF1/STEAP4/NCF2/CYBA/NQO2	5
GO:0016417	S-acyltransferase activity	2/393	30/18367	0.134444977973919	0.426401474260419	ZDHHC18/GLUL	2
GO:0046966	thyroid hormone receptor binding	2/393	30/18367	0.134444977973919	0.426401474260419	JMJD1C/TAF7	2
GO:0008157	protein phosphatase 1 binding	2/393	31/18367	0.141781636818888	0.447476678155223	LILRB2/PPP1R15A	2
GO:0050699	WW domain binding	2/393	32/18367	0.14920118785176	0.468607614272277	LITAF/DAZAP2	2
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	6/393	170/18367	0.158107698585757	0.494182033743888	PTGS2/CYP4F3/KDM6B/EGLN1/KDM5A/TET2	6
GO:0042578	phosphoric ester hydrolase activity	11/393	366/18367	0.163390308394222	0.506082477543717	PTPRC/LRRK2/ALPL/DUSP1/PTPRE/PPP2R5A/PTEN/CPPED1/SSH2/PTPN6/PPP3CA	11
GO:0030291	protein serine/threonine kinase inhibitor activity	2/393	34/18367	0.164261700593788	0.506082477543717	CDKN2D/PRKAR1A	2
GO:0043548	phosphatidylinositol 3-kinase binding	2/393	34/18367	0.164261700593788	0.506082477543717	CORO1A/PIK3AP1	2
GO:1901981	phosphatidylinositol phosphate binding	6/393	173/18367	0.167234664634019	0.508221048128441	ARHGAP9/NCF4/SDCBP/IQGAP1/OSBPL8/PICALM	6
GO:0004713	protein tyrosine kinase activity	5/393	136/18367	0.16723740399544	0.508221048128441	LYN/HCK/FGR/JAK1/IGF2R	5
GO:0046982	protein heterodimerization activity	10/393	328/18367	0.167312338873814	0.508221048128441	GCA/BCL2A1/MCL1/CYBA/CEBPB/IRAK3/SDCBP/SOS2/TAF7/HIF1A	10
GO:0097110	scaffold protein binding	3/393	67/18367	0.172893852746226	0.522281928726427	LYN/TREM1/VIM	3
GO:0008238	exopeptidase activity	4/393	103/18367	0.179245697768697	0.522281928726427	QPCT/AGTPBP1/NPEPPS/MME	4
GO:0005484	SNAP receptor activity	2/393	36/18367	0.17957448941521	0.522281928726427	STX3/STX7	2
GO:0015248	sterol transporter activity	2/393	36/18367	0.17957448941521	0.522281928726427	TSPO/OSBPL8	2
GO:0023023	MHC protein complex binding	2/393	36/18367	0.17957448941521	0.522281928726427	B2M/LILRB2	2
GO:0005518	collagen binding	3/393	69/18367	0.183564805487402	0.522281928726427	CTSS/CD44/PAK1	3
GO:0005525	GTP binding	11/393	377/18367	0.186605784428498	0.522281928726427	LRRK2/MX2/RAC2/TUBA1A/RAB27A/RALB/RHOG/GIMAP4/NIN/RAB8B/RAB7A	11
GO:0016409	palmitoyltransferase activity	2/393	37/18367	0.187310285308145	0.522281928726427	ZDHHC18/GLUL	2
GO:0046915	transition metal ion transmembrane transporter activity	2/393	37/18367	0.187310285308145	0.522281928726427	SLC25A37/SLC11A1	2
GO:0071949	FAD binding	2/393	37/18367	0.187310285308145	0.522281928726427	STEAP4/NQO2	2
GO:1990782	protein tyrosine kinase binding	4/393	105/18367	0.187812088447507	0.522281928726427	ITGAX/PTEN/DAZAP2/CPNE3	4
GO:0004857	enzyme inhibitor activity	3/393	70/18367	0.188964779637448	0.522281928726427	LRRK2/TXNIP/OAZ1	3
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	3/393	71/18367	0.194405090968895	0.522281928726427	VNN2/PGLYRP1/CAT	3
GO:0005031	tumor necrosis factor-activated receptor activity	1/393	10/18367	0.19454396417785	0.522281928726427	TNFRSF1B	1
GO:0005384	manganese ion transmembrane transporter activity	1/393	10/18367	0.19454396417785	0.522281928726427	SLC11A1	1
GO:0008190	eukaryotic initiation factor 4E binding	1/393	10/18367	0.19454396417785	0.522281928726427	DDX3X	1
GO:0008330	protein tyrosine/threonine phosphatase activity	1/393	10/18367	0.19454396417785	0.522281928726427	DUSP1	1
GO:0016595	glutamate binding	1/393	10/18367	0.19454396417785	0.522281928726427	GLUL	1
GO:0017002	activin-activated receptor activity	1/393	10/18367	0.19454396417785	0.522281928726427	TGFBR2	1
GO:0019869	chloride channel inhibitor activity	1/393	10/18367	0.19454396417785	0.522281928726427	STX7	1
GO:0030957	Tat protein binding	1/393	10/18367	0.19454396417785	0.522281928726427	ACTB	1
GO:0034713	type I transforming growth factor beta receptor binding	1/393	10/18367	0.19454396417785	0.522281928726427	TGFBR2	1
GO:0035374	chondroitin sulfate binding	1/393	10/18367	0.19454396417785	0.522281928726427	ADGRE2	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/393	10/18367	0.19454396417785	0.522281928726427	PIK3AP1	1
GO:0045294	alpha-catenin binding	1/393	10/18367	0.19454396417785	0.522281928726427	NUMB	1
GO:0045503	dynein light chain binding	1/393	10/18367	0.19454396417785	0.522281928726427	GLUL	1
GO:0071723	lipopeptide binding	1/393	10/18367	0.19454396417785	0.522281928726427	TLR1	1
GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1/393	10/18367	0.19454396417785	0.522281928726427	CFLAR	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	5/393	144/18367	0.196184458312359	0.52450968813263	MGAM/TLR1/PIK3AP1/LYZ/CTBS	5
GO:0008235	metalloexopeptidase activity	3/393	72/18367	0.199883764729662	0.529060524564312	QPCT/AGTPBP1/NPEPPS	3
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/393	39/18367	0.202912274103605	0.529060524564312	ARHGAP9/IQGAP1	2
GO:0004674	protein serine/threonine kinase activity	11/393	386/18367	0.206667120254981	0.529060524564312	LRRK2/PRKCB/IRAK3/STK17B/STK4/MAP3K2/CPNE3/TGFBR2/PAK2/PAK1/MAPK1	11
GO:0008528	G protein-coupled peptide receptor activity	5/393	147/18367	0.207463762293219	0.529060524564312	CXCR2/FPR1/FPR2/CXCR1/CXCR4	5
GO:0015144	carbohydrate transmembrane transporter activity	2/393	40/18367	0.210767756397337	0.529060524564312	AQP9/SLC2A3	2
GO:0019905	syntaxin binding	3/393	74/18367	0.21094839392494	0.529060524564312	LRRK2/STX7/STXBP3	3
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/393	11/18367	0.211787752491742	0.529060524564312	BCL6	1
GO:0005078	MAP-kinase scaffold activity	1/393	11/18367	0.211787752491742	0.529060524564312	IQGAP1	1
GO:0008503	benzodiazepine receptor activity	1/393	11/18367	0.211787752491742	0.529060524564312	TSPO	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/393	11/18367	0.211787752491742	0.529060524564312	PRKAR1A	1
GO:0017128	phospholipid scramblase activity	1/393	11/18367	0.211787752491742	0.529060524564312	PLSCR1	1
GO:0031434	mitogen-activated protein kinase kinase binding	1/393	11/18367	0.211787752491742	0.529060524564312	TRIB1	1
GO:0032052	bile acid binding	1/393	11/18367	0.211787752491742	0.529060524564312	PYGL	1
GO:0035197	siRNA binding	1/393	11/18367	0.211787752491742	0.529060524564312	DICER1	1
GO:0047676	arachidonate-CoA ligase activity	1/393	11/18367	0.211787752491742	0.529060524564312	ACSL1	1
GO:0070513	death domain binding	1/393	11/18367	0.211787752491742	0.529060524564312	MCL1	1
GO:1901612	cardiolipin binding	1/393	11/18367	0.211787752491742	0.529060524564312	MME	1
GO:0008237	metallopeptidase activity	6/393	190/18367	0.22276286091154	0.541923627393729	MMP25/QPCT/AGTPBP1/NPEPPS/MME/NRDC	6
GO:0035091	phosphatidylinositol binding	8/393	271/18367	0.225834035288464	0.541923627393729	NCF1/ARHGAP9/NCF4/SNX10/SDCBP/IQGAP1/OSBPL8/PICALM	8
GO:0001046	core promoter sequence-specific DNA binding	2/393	42/18367	0.226562470235881	0.541923627393729	FOS/CEBPB	2
GO:0003724	RNA helicase activity	3/393	77/18367	0.227784805963699	0.541923627393729	DDX60L/DDX3X/DDX5	3
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/393	12/18367	0.228663292547895	0.541923627393729	CDKN2D	1
GO:0005024	transforming growth factor beta-activated receptor activity	1/393	12/18367	0.228663292547895	0.541923627393729	TGFBR2	1
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/393	12/18367	0.228663292547895	0.541923627393729	MAPK1	1
GO:0015166	polyol transmembrane transporter activity	1/393	12/18367	0.228663292547895	0.541923627393729	AQP9	1
GO:0017154	semaphorin receptor activity	1/393	12/18367	0.228663292547895	0.541923627393729	PLXNC1	1
GO:0017166	vinculin binding	1/393	12/18367	0.228663292547895	0.541923627393729	ACTN1	1
GO:0031543	peptidyl-proline dioxygenase activity	1/393	12/18367	0.228663292547895	0.541923627393729	EGLN1	1
GO:0043422	protein kinase B binding	1/393	12/18367	0.228663292547895	0.541923627393729	ARRB2	1
GO:0089720	caspase binding	1/393	12/18367	0.228663292547895	0.541923627393729	CARD16	1
GO:0097677	STAT family protein binding	1/393	12/18367	0.228663292547895	0.541923627393729	SPI1	1
GO:0030971	receptor tyrosine kinase binding	3/393	78/18367	0.233453291992965	0.543254943280394	ITGAX/DAZAP2/CPNE3	3
GO:0019001	guanyl nucleotide binding	11/393	398/18367	0.2347718396966	0.543254943280394	LRRK2/MX2/RAC2/TUBA1A/RAB27A/RALB/RHOG/GIMAP4/NIN/RAB8B/RAB7A	11
GO:0032561	guanyl ribonucleotide binding	11/393	398/18367	0.2347718396966	0.543254943280394	LRRK2/MX2/RAC2/TUBA1A/RAB27A/RALB/RHOG/GIMAP4/NIN/RAB8B/RAB7A	11
GO:0008186	ATP-dependent activity, acting on RNA	3/393	79/18367	0.239146891289171	0.543254943280394	DDX60L/DDX3X/DDX5	3
GO:0004000	adenosine deaminase activity	1/393	13/18367	0.245178428806607	0.543254943280394	ADAR	1
GO:0004312	fatty acid synthase activity	1/393	13/18367	0.245178428806607	0.543254943280394	ELOVL5	1
GO:0005035	death receptor activity	1/393	13/18367	0.245178428806607	0.543254943280394	TNFRSF1B	1
GO:0008179	adenylate cyclase binding	1/393	13/18367	0.245178428806607	0.543254943280394	CAP1	1
GO:0015250	water channel activity	1/393	13/18367	0.245178428806607	0.543254943280394	AQP9	1
GO:0016840	carbon-nitrogen lyase activity	1/393	13/18367	0.245178428806607	0.543254943280394	APMAP	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/393	13/18367	0.245178428806607	0.543254943280394	DUSP1	1
GO:0031404	chloride ion binding	1/393	13/18367	0.245178428806607	0.543254943280394	NQO2	1
GO:0032036	myosin heavy chain binding	1/393	13/18367	0.245178428806607	0.543254943280394	CORO1A	1
GO:0032454	histone H3-methyl-lysine-9 demethylase activity	1/393	13/18367	0.245178428806607	0.543254943280394	JMJD1C	1
GO:0034450	ubiquitin-ubiquitin ligase activity	1/393	13/18367	0.245178428806607	0.543254943280394	PELI1	1
GO:0039706	co-receptor binding	1/393	13/18367	0.245178428806607	0.543254943280394	LRRK2	1
GO:0051011	microtubule minus-end binding	1/393	13/18367	0.245178428806607	0.543254943280394	NIN	1
GO:0070700	BMP receptor binding	1/393	13/18367	0.245178428806607	0.543254943280394	PYCARD	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/393	13/18367	0.245178428806607	0.543254943280394	HSD17B11	1
GO:0003712	transcription coregulator activity	13/393	489/18367	0.25033240715028	0.54962596354831	BASP1/PRKCB/BTG2/JMJD1C/MED13L/ACTN1/BTG1/TLE3/NCOA1/HSPA1A/KDM5A/SF1/NCOA4	13
GO:0048156	tau protein binding	2/393	45/18367	0.2503940948324	0.54962596354831	ACTB/PICALM	2
GO:0035591	signaling adaptor activity	3/393	81/18367	0.250602255404562	0.54962596354831	LRRK2/IQGAP1/STAT3	3
GO:0061980	regulatory RNA binding	2/393	46/18367	0.258357857388419	0.556871720645963	NEAT1/DICER1	2
GO:0004298	threonine-type endopeptidase activity	1/393	14/18367	0.261340839043014	0.556871720645963	PSMB9	1
GO:0004707	MAP kinase activity	1/393	14/18367	0.261340839043014	0.556871720645963	MAPK1	1
GO:0015926	glucosidase activity	1/393	14/18367	0.261340839043014	0.556871720645963	MGAM	1
GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	1/393	14/18367	0.261340839043014	0.556871720645963	HSD17B11	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/393	14/18367	0.261340839043014	0.556871720645963	P2RY13	1
GO:0140666	annealing activity	1/393	14/18367	0.261340839043014	0.556871720645963	DDX3X	1
GO:0003730	mRNA 3'-UTR binding	6/393	201/18367	0.261533510973064	0.556871720645963	ZFP36/CELF2/ZFP36L1/ZFP36L2/DDX5/CPEB4	6
GO:0035254	glutamate receptor binding	2/393	47/18367	0.266324855891598	0.556871720645963	PTEN/FLOT2	2
GO:0008135	translation factor activity, RNA binding	3/393	84/18367	0.267929490706587	0.556871720645963	ABTB1/EIF1/CPEB4	3
GO:0015026	coreceptor activity	2/393	48/18367	0.274291315521943	0.556871720645963	CXCR4/LY96	2
GO:0048020	CCR chemokine receptor binding	2/393	48/18367	0.274291315521943	0.556871720645963	JAK1/STAT3	2
GO:0120013	lipid transfer activity	2/393	48/18367	0.274291315521943	0.556871720645963	TSPO/OSBPL8	2
GO:0004467	long-chain fatty acid-CoA ligase activity	1/393	15/18367	0.277158037880049	0.556871720645963	ACSL1	1
GO:0016846	carbon-sulfur lyase activity	1/393	15/18367	0.277158037880049	0.556871720645963	ALOX5AP	1
GO:0019215	intermediate filament binding	1/393	15/18367	0.277158037880049	0.556871720645963	VIM	1
GO:0032794	GTPase activating protein binding	1/393	15/18367	0.277158037880049	0.556871720645963	FMNL1	1
GO:0042043	neurexin family protein binding	1/393	15/18367	0.277158037880049	0.556871720645963	SDCBP	1
GO:0042809	vitamin D receptor binding	1/393	15/18367	0.277158037880049	0.556871720645963	TAF7	1
GO:0048185	activin binding	1/393	15/18367	0.277158037880049	0.556871720645963	TGFBR2	1
GO:0050998	nitric-oxide synthase binding	1/393	15/18367	0.277158037880049	0.556871720645963	ACTB	1
GO:0051139	metal ion:proton antiporter activity	1/393	15/18367	0.277158037880049	0.556871720645963	SLC11A1	1
GO:0071933	Arp2/3 complex binding	1/393	15/18367	0.277158037880049	0.556871720645963	GMFG	1
GO:1901611	phosphatidylglycerol binding	1/393	15/18367	0.277158037880049	0.556871720645963	MME	1
GO:0008009	chemokine activity	2/393	49/18367	0.282253620716219	0.556871720645963	CXCL8/CKLF	2
GO:0016763	pentosyltransferase activity	2/393	49/18367	0.282253620716219	0.556871720645963	NAMPT/TYMP	2
GO:0098632	cell-cell adhesion mediator activity	2/393	49/18367	0.282253620716219	0.556871720645963	S100A11/TMOD3	2
GO:0042826	histone deacetylase binding	4/393	127/18367	0.28882911674869	0.556871720645963	SPI1/CEBPB/HIF1A/HSPA1A	4
GO:0015485	cholesterol binding	2/393	50/18367	0.290208310110613	0.556871720645963	TSPO/OSBPL8	2
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/393	50/18367	0.290208310110613	0.556871720645963	CDKN2D/CCNL1	2
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/393	50/18367	0.290208310110613	0.556871720645963	TLR1/PIK3AP1	2
GO:0000900	translation repressor activity, mRNA regulatory element binding	1/393	16/18367	0.292637380246719	0.556871720645963	CPEB4	1
GO:0004698	calcium-dependent protein kinase C activity	1/393	16/18367	0.292637380246719	0.556871720645963	PRKCB	1
GO:0005092	GDP-dissociation inhibitor activity	1/393	16/18367	0.292637380246719	0.556871720645963	ARHGDIB	1
GO:0005372	water transmembrane transporter activity	1/393	16/18367	0.292637380246719	0.556871720645963	AQP9	1
GO:0016208	AMP binding	1/393	16/18367	0.292637380246719	0.556871720645963	PYGL	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/393	16/18367	0.292637380246719	0.556871720645963	DICER1	1
GO:0035173	histone kinase activity	1/393	16/18367	0.292637380246719	0.556871720645963	PRKCB	1
GO:0035497	cAMP response element binding	1/393	16/18367	0.292637380246719	0.556871720645963	CREB5	1
GO:0050135	NAD(P)+ nucleosidase activity	1/393	16/18367	0.292637380246719	0.556871720645963	TLR1	1
GO:0050700	CARD domain binding	1/393	16/18367	0.292637380246719	0.556871720645963	CARD16	1
GO:0061809	NAD+ nucleotidase, cyclic ADP-ribose generating	1/393	16/18367	0.292637380246719	0.556871720645963	TLR1	1
GO:0070402	NADPH binding	1/393	16/18367	0.292637380246719	0.556871720645963	LBR	1
GO:0070492	oligosaccharide binding	1/393	16/18367	0.292637380246719	0.556871720645963	SELL	1
GO:1990380	Lys48-specific deubiquitinase activity	1/393	16/18367	0.292637380246719	0.556871720645963	USP15	1
GO:0019888	protein phosphatase regulator activity	3/393	89/18367	0.297081122976914	0.55780835826843	PPP2R5A/BOD1L1/PPP1R15A	3
GO:0051117	ATPase binding	3/393	89/18367	0.297081122976914	0.55780835826843	SNX10/RALB/PPP3CA	3
GO:0005543	phospholipid binding	12/393	466/18367	0.297101717325152	0.55780835826843	NCF1/ARHGAP9/NCF4/PREX1/SNX10/SDCBP/IQGAP1/ARHGAP26/OSBPL8/PICALM/CPNE3/MME	12
GO:0031072	heat shock protein binding	4/393	129/18367	0.298431000126147	0.55780835826843	ZFP36/ITGB2/HIF1A/HSPA1A	4
GO:0003823	antigen binding	5/393	171/18367	0.303806119100825	0.55780835826843	HLA-B/HLA-C/HLA-E/HLA-A/FCN1	5
GO:0003951	NAD+ kinase activity	1/393	17/18367	0.30778606476326	0.55780835826843	NADK	1
GO:0004697	protein kinase C activity	1/393	17/18367	0.30778606476326	0.55780835826843	PRKCB	1
GO:0005149	interleukin-1 receptor binding	1/393	17/18367	0.30778606476326	0.55780835826843	IL1B	1
GO:0008484	sulfuric ester hydrolase activity	1/393	17/18367	0.30778606476326	0.55780835826843	IDS	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/393	17/18367	0.30778606476326	0.55780835826843	PYCARD	1
GO:0017081	chloride channel regulator activity	1/393	17/18367	0.30778606476326	0.55780835826843	STX7	1
GO:0030169	low-density lipoprotein particle binding	1/393	17/18367	0.30778606476326	0.55780835826843	SORL1	1
GO:0031489	myosin V binding	1/393	17/18367	0.30778606476326	0.55780835826843	RAB27A	1
GO:0043395	heparan sulfate proteoglycan binding	1/393	17/18367	0.30778606476326	0.55780835826843	PTPRC	1
GO:0046965	retinoid X receptor binding	1/393	17/18367	0.30778606476326	0.55780835826843	NCOA1	1
GO:0050780	dopamine receptor binding	1/393	17/18367	0.30778606476326	0.55780835826843	ARRB2	1
GO:0052745	inositol phosphate phosphatase activity	1/393	17/18367	0.30778606476326	0.55780835826843	PTEN	1
GO:0016407	acetyltransferase activity	3/393	91/18367	0.308800195247004	0.558083034426849	SAT1/LPCAT2/NCOA1	3
GO:0050661	NADP binding	2/393	53/18367	0.313994280606758	0.564317498757146	LBR/CAT	2
GO:1901618	organic hydroxy compound transmembrane transporter activity	2/393	53/18367	0.313994280606758	0.564317498757146	AQP9/SLC16A3	2
GO:0004303	estradiol 17-beta-dehydrogenase activity	1/393	18/18367	0.322611137054706	0.568744974589632	HSD17B11	1
GO:0004438	phosphatidylinositol-3-phosphatase activity	1/393	18/18367	0.322611137054706	0.568744974589632	PTEN	1
GO:0004708	MAP kinase kinase activity	1/393	18/18367	0.322611137054706	0.568744974589632	MAPK1	1
GO:0016755	aminoacyltransferase activity	1/393	18/18367	0.322611137054706	0.568744974589632	QPCT	1
GO:0033549	MAP kinase phosphatase activity	1/393	18/18367	0.322611137054706	0.568744974589632	DUSP1	1
GO:0042834	peptidoglycan binding	1/393	18/18367	0.322611137054706	0.568744974589632	PGLYRP1	1
GO:0045236	CXCR chemokine receptor binding	1/393	18/18367	0.322611137054706	0.568744974589632	CXCL8	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/393	94/18367	0.326403988347127	0.57386788168639	MGAM/LYZ/CTBS	3
GO:0003746	translation elongation factor activity	1/393	19/18367	0.337119492994403	0.58633417195532	ABTB1	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/393	19/18367	0.337119492994403	0.58633417195532	TGFBR2	1
GO:0035613	RNA stem-loop binding	1/393	19/18367	0.337119492994403	0.58633417195532	DDX3X	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/393	19/18367	0.337119492994403	0.58633417195532	PTEN	1
GO:0005548	phospholipid transporter activity	2/393	57/18367	0.345417313144795	0.593479555027844	OSBPL8/PLSCR1	2
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	8/393	310/18367	0.345702502433291	0.593479555027844	MXD1/BCL6/SPI1/CEBPB/IFI16/LRRFIP1/NFIL3/BACH1	8
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/393	20/18367	0.351317881878925	0.593479555027844	TAF7	1
GO:0001972	retinoic acid binding	1/393	20/18367	0.351317881878925	0.593479555027844	IGF2R	1
GO:0016018	cyclosporin A binding	1/393	20/18367	0.351317881878925	0.593479555027844	PPP3CA	1
GO:0016505	peptidase activator activity involved in apoptotic process	1/393	20/18367	0.351317881878925	0.593479555027844	PYCARD	1
GO:0030296	protein tyrosine kinase activator activity	1/393	20/18367	0.351317881878925	0.593479555027844	PAK2	1
GO:0030506	ankyrin binding	1/393	20/18367	0.351317881878925	0.593479555027844	PTPRC	1
GO:0031418	L-ascorbic acid binding	1/393	20/18367	0.351317881878925	0.593479555027844	EGLN1	1
GO:0031690	adrenergic receptor binding	1/393	20/18367	0.351317881878925	0.593479555027844	ARRB2	1
GO:0061608	nuclear import signal receptor activity	1/393	20/18367	0.351317881878925	0.593479555027844	KPNA4	1
GO:0001217	DNA-binding transcription repressor activity	8/393	313/18367	0.355365782912319	0.598754326938204	MXD1/BCL6/SPI1/CEBPB/IFI16/LRRFIP1/NFIL3/BACH1	8
GO:0008017	microtubule binding	7/393	271/18367	0.360756999137687	0.599727798146432	S100A8/S100A9/LRRK2/MX2/NIN/CEP350/KATNBL1	7
GO:0098631	cell adhesion mediator activity	2/393	59/18367	0.360956914194208	0.599727798146432	S100A11/TMOD3	2
GO:0016887	ATP hydrolysis activity	7/393	272/18367	0.364244979349803	0.599727798146432	SMCHD1/DDX60L/DDX3X/DDX5/HSPA1A/VPS4B/RNF213	7
GO:0001614	purinergic nucleotide receptor activity	1/393	21/18367	0.365212909535849	0.599727798146432	P2RY13	1
GO:0008373	sialyltransferase activity	1/393	21/18367	0.365212909535849	0.599727798146432	ST8SIA4	1
GO:0008391	arachidonic acid monooxygenase activity	1/393	21/18367	0.365212909535849	0.599727798146432	CYP4F3	1
GO:0016502	nucleotide receptor activity	1/393	21/18367	0.365212909535849	0.599727798146432	P2RY13	1
GO:0070577	lysine-acetylated histone binding	1/393	21/18367	0.365212909535849	0.599727798146432	PHIP	1
GO:0140033	acetylation-dependent protein binding	1/393	21/18367	0.365212909535849	0.599727798146432	PHIP	1
GO:1990381	ubiquitin-specific protease binding	1/393	21/18367	0.365212909535849	0.599727798146432	PTEN	1
GO:0001786	phosphatidylserine binding	2/393	60/18367	0.368675652990242	0.600712607263914	OSBPL8/MME	2
GO:0032934	sterol binding	2/393	60/18367	0.368675652990242	0.600712607263914	TSPO/OSBPL8	2
GO:0005539	glycosaminoglycan binding	6/393	230/18367	0.369966207453916	0.600712607263914	PTPRC/SELL/PGLYRP1/ADGRE2/CD44/TGFBR2	6
GO:0003714	transcription corepressor activity	5/393	187/18367	0.371380700678652	0.600712607263914	BASP1/BTG2/TLE3/HSPA1A/SF1	5
GO:0004602	glutathione peroxidase activity	1/393	22/18367	0.378811041365807	0.600712607263914	ALOX5AP	1
GO:0005355	glucose transmembrane transporter activity	1/393	22/18367	0.378811041365807	0.600712607263914	SLC2A3	1
GO:0005537	mannose binding	1/393	22/18367	0.378811041365807	0.600712607263914	IGF2R	1
GO:0005540	hyaluronic acid binding	1/393	22/18367	0.378811041365807	0.600712607263914	CD44	1
GO:0008093	cytoskeletal anchor activity	1/393	22/18367	0.378811041365807	0.600712607263914	SDCBP	1
GO:0008320	protein transmembrane transporter activity	1/393	22/18367	0.378811041365807	0.600712607263914	MCL1	1
GO:0015149	hexose transmembrane transporter activity	1/393	22/18367	0.378811041365807	0.600712607263914	SLC2A3	1
GO:0015645	fatty acid ligase activity	1/393	22/18367	0.378811041365807	0.600712607263914	ACSL1	1
GO:0055106	ubiquitin-protein transferase regulator activity	1/393	22/18367	0.378811041365807	0.600712607263914	TRIB1	1
GO:0120020	cholesterol transfer activity	1/393	22/18367	0.378811041365807	0.600712607263914	TSPO	1
GO:1990841	promoter-specific chromatin binding	2/393	62/18367	0.384000699857185	0.605491020625693	EGR1/DDX5	2
GO:0008234	cysteine-type peptidase activity	5/393	190/18367	0.384121387215413	0.605491020625693	CTSS/CFLAR/PYCARD/USP15/USP10	5
GO:0005158	insulin receptor binding	1/393	23/18367	0.392118605320194	0.605491020625693	PHIP	1
GO:0005212	structural constituent of eye lens	1/393	23/18367	0.392118605320194	0.605491020625693	VIM	1
GO:0008143	poly(A) binding	1/393	23/18367	0.392118605320194	0.605491020625693	DDX3X	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/393	23/18367	0.392118605320194	0.605491020625693	PRKCB	1
GO:0015299	solute:proton antiporter activity	1/393	23/18367	0.392118605320194	0.605491020625693	SLC11A1	1
GO:0016849	phosphorus-oxygen lyase activity	1/393	23/18367	0.392118605320194	0.605491020625693	RNASET2	1
GO:0030552	cAMP binding	1/393	23/18367	0.392118605320194	0.605491020625693	PRKAR1A	1
GO:0050750	low-density lipoprotein particle receptor binding	1/393	23/18367	0.392118605320194	0.605491020625693	PICALM	1
GO:0120015	sterol transfer activity	1/393	23/18367	0.392118605320194	0.605491020625693	TSPO	1
GO:0019208	phosphatase regulator activity	3/393	107/18367	0.402207817765394	0.612445657116554	PPP2R5A/BOD1L1/PPP1R15A	3
GO:0008171	O-methyltransferase activity	1/393	24/18367	0.405141794815897	0.612445657116554	PCMTD1	1
GO:0010857	calcium-dependent protein kinase activity	1/393	24/18367	0.405141794815897	0.612445657116554	PRKCB	1
GO:0015145	monosaccharide transmembrane transporter activity	1/393	24/18367	0.405141794815897	0.612445657116554	SLC2A3	1
GO:0043274	phospholipase binding	1/393	24/18367	0.405141794815897	0.612445657116554	WAS	1
GO:0043495	protein-membrane adaptor activity	1/393	24/18367	0.405141794815897	0.612445657116554	MYH9	1
GO:0050431	transforming growth factor beta binding	1/393	24/18367	0.405141794815897	0.612445657116554	TGFBR2	1
GO:0070003	threonine-type peptidase activity	1/393	24/18367	0.405141794815897	0.612445657116554	PSMB9	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/393	24/18367	0.405141794815897	0.612445657116554	PYCARD	1
GO:0030145	manganese ion binding	2/393	65/18367	0.406679318795427	0.613336874733429	SOD2/GLUL	2
GO:0090079	translation regulator activity, nucleic acid binding	3/393	108/18367	0.407959452979697	0.613836665297358	ABTB1/EIF1/CPEB4	3
GO:0002039	p53 binding	2/393	66/18367	0.414149706734865	0.618701776928309	HIF1A/USP10	2
GO:0043022	ribosome binding	2/393	66/18367	0.414149706734865	0.618701776928309	RICTOR/CPEB4	2
GO:0005112	Notch binding	1/393	25/18367	0.417886671588363	0.618701776928309	CUL3	1
GO:0005242	inward rectifier potassium channel activity	1/393	25/18367	0.417886671588363	0.618701776928309	KCNJ15	1
GO:0030247	polysaccharide binding	1/393	25/18367	0.417886671588363	0.618701776928309	CLEC7A	1
GO:0034237	protein kinase A regulatory subunit binding	1/393	25/18367	0.417886671588363	0.618701776928309	PJA2	1
GO:0070330	aromatase activity	1/393	25/18367	0.417886671588363	0.618701776928309	CYP4F3	1
GO:0042393	histone binding	6/393	244/18367	0.42338271242133	0.625407796658905	PRKCB/ANP32A/USP15/TAF7/KDM5A/PHIP	6
GO:0004222	metalloendopeptidase activity	3/393	111/18367	0.425110706836141	0.625713217998561	MMP25/MME/NRDC	3
GO:0008080	N-acetyltransferase activity	2/393	68/18367	0.428947685091343	0.625713217998561	SAT1/NCOA1	2
GO:0004386	helicase activity	4/393	156/18367	0.429129712815651	0.625713217998561	DDX60L/DDX3X/DICER1/DDX5	4
GO:0004364	glutathione transferase activity	1/393	26/18367	0.430359168484327	0.625713217998561	ALOX5AP	1
GO:0030371	translation repressor activity	1/393	26/18367	0.430359168484327	0.625713217998561	CPEB4	1
GO:0042923	neuropeptide binding	1/393	26/18367	0.430359168484327	0.625713217998561	SORL1	1
GO:0042974	retinoic acid receptor binding	1/393	26/18367	0.430359168484327	0.625713217998561	NCOA1	1
GO:0004521	endoribonuclease activity	2/393	69/18367	0.436272547169072	0.627937751426435	RNASET2/DICER1	2
GO:0003774	cytoskeletal motor activity	3/393	114/18367	0.442087416817948	0.627937751426435	MYO1F/MYH9/MYL6	3
GO:0015491	cation:cation antiporter activity	1/393	27/18367	0.442565092195447	0.627937751426435	SLC11A1	1
GO:0016405	CoA-ligase activity	1/393	27/18367	0.442565092195447	0.627937751426435	ACSL1	1
GO:0022884	macromolecule transmembrane transporter activity	1/393	27/18367	0.442565092195447	0.627937751426435	MCL1	1
GO:0023026	MHC class II protein complex binding	1/393	27/18367	0.442565092195447	0.627937751426435	B2M	1
GO:0030507	spectrin binding	1/393	27/18367	0.442565092195447	0.627937751426435	PTPRC	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/393	27/18367	0.442565092195447	0.627937751426435	PTEN	1
GO:0048027	mRNA 5'-UTR binding	1/393	27/18367	0.442565092195447	0.627937751426435	DDX3X	1
GO:0051119	sugar transmembrane transporter activity	1/393	27/18367	0.442565092195447	0.627937751426435	SLC2A3	1
GO:0070006	metalloaminopeptidase activity	1/393	27/18367	0.442565092195447	0.627937751426435	NPEPPS	1
GO:0030674	protein-macromolecule adaptor activity	7/393	296/18367	0.448087610691367	0.633167717332314	LRRK2/SDCBP/IQGAP1/STX3/STAT3/STX7/MYH9	7
GO:0004842	ubiquitin-protein transferase activity	10/393	433/18367	0.448208368683462	0.633167717332314	RNF24/RNF149/PELI1/FBXL5/UBE2D1/UBE2D3/PJA2/UBE2B/CUL3/RNF213	10
GO:0004540	ribonuclease activity	3/393	116/18367	0.453296944201416	0.635136180301022	RNASET2/DICER1/N4BP1	3
GO:0001968	fibronectin binding	1/393	28/18367	0.454510125934116	0.635136180301022	CTSS	1
GO:0017056	structural constituent of nuclear pore	1/393	28/18367	0.454510125934116	0.635136180301022	NUP214	1
GO:0043236	laminin binding	1/393	28/18367	0.454510125934116	0.635136180301022	CTSS	1
GO:0070325	lipoprotein particle receptor binding	1/393	28/18367	0.454510125934116	0.635136180301022	PICALM	1
GO:0030276	clathrin binding	2/393	72/18367	0.457935904496946	0.637698290355324	LRRK2/PICALM	2
GO:0035064	methylated histone binding	2/393	73/18367	0.465049624493395	0.637698290355324	TAF7/KDM5A	2
GO:0140034	methylation-dependent protein binding	2/393	73/18367	0.465049624493395	0.637698290355324	TAF7/KDM5A	2
GO:0004181	metallocarboxypeptidase activity	1/393	29/18367	0.466199832052656	0.637698290355324	AGTPBP1	1
GO:0005520	insulin-like growth factor binding	1/393	29/18367	0.466199832052656	0.637698290355324	IGF2R	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/393	29/18367	0.466199832052656	0.637698290355324	LBR	1
GO:0033612	receptor serine/threonine kinase binding	1/393	29/18367	0.466199832052656	0.637698290355324	PYCARD	1
GO:0051787	misfolded protein binding	1/393	29/18367	0.466199832052656	0.637698290355324	HSPA1A	1
GO:0070273	phosphatidylinositol-4-phosphate binding	1/393	29/18367	0.466199832052656	0.637698290355324	OSBPL8	1
GO:0070717	poly-purine tract binding	1/393	29/18367	0.466199832052656	0.637698290355324	DDX3X	1
GO:0048018	receptor ligand activity	11/393	487/18367	0.470633910777436	0.64240535922574	NAMPT/CXCL8/CMTM2/GMFG/OSM/LTB/IL1B/TNFSF13B/TNFSF10/CKLF/TYMP	11
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/393	30/18367	0.477639654607095	0.650595487433243	HSD17B11	1
GO:0016878	acid-thiol ligase activity	1/393	31/18367	0.488834921866702	0.658908738432825	ACSL1	1
GO:0071813	lipoprotein particle binding	1/393	31/18367	0.488834921866702	0.658908738432825	SORL1	1
GO:0071814	protein-lipid complex binding	1/393	31/18367	0.488834921866702	0.658908738432825	SORL1	1
GO:0090482	vitamin transmembrane transporter activity	1/393	31/18367	0.488834921866702	0.658908738432825	SLC2A3	1
GO:0140318	protein transporter activity	1/393	31/18367	0.488834921866702	0.658908738432825	MCL1	1
GO:0030546	signaling receptor activator activity	11/393	495/18367	0.492306557995383	0.662208613353456	NAMPT/CXCL8/CMTM2/GMFG/OSM/LTB/IL1B/TNFSF13B/TNFSF10/CKLF/TYMP	11
GO:0001221	transcription coregulator binding	2/393	78/18367	0.499771035032104	0.666731297225681	HIF1A/NFE2L2	2
GO:0001223	transcription coactivator binding	1/393	32/18367	0.49979084877041	0.666731297225681	HIF1A	1
GO:0030332	cyclin binding	1/393	32/18367	0.49979084877041	0.666731297225681	CUL3	1
GO:0051721	protein phosphatase 2A binding	1/393	32/18367	0.49979084877041	0.666731297225681	BOD1L1	1
GO:0106310	protein serine kinase activity	8/393	360/18367	0.506944391705648	0.674084924382299	LRRK2/PRKCB/STK17B/STK4/MAP3K2/PAK2/PAK1/MAPK1	8
GO:0001530	lipopolysaccharide binding	1/393	33/18367	0.510512539331262	0.674084924382299	LY96	1
GO:0005154	epidermal growth factor receptor binding	1/393	33/18367	0.510512539331262	0.674084924382299	PLSCR1	1
GO:0031369	translation initiation factor binding	1/393	33/18367	0.510512539331262	0.674084924382299	DDX3X	1
GO:0051427	hormone receptor binding	1/393	33/18367	0.510512539331262	0.674084924382299	JAK1	1
GO:0000287	magnesium ion binding	5/393	221/18367	0.512945827995474	0.675918433224179	LRRK2/IRAK3/STK4/GLUL/PLSCR1	5
GO:0140678	molecular function inhibitor activity	3/393	128/18367	0.518391165616823	0.676888007784162	LRRK2/TXNIP/OAZ1	3
GO:0019787	ubiquitin-like protein transferase activity	10/393	458/18367	0.519164058461452	0.676888007784162	RNF24/RNF149/PELI1/FBXL5/UBE2D1/UBE2D3/PJA2/UBE2B/CUL3/RNF213	10
GO:0005085	guanyl-nucleotide exchange factor activity	5/393	223/18367	0.520924205475256	0.676888007784162	DENND3/CYTH4/PREX1/SOS2/DOCK5	5
GO:0016229	steroid dehydrogenase activity	1/393	34/18367	0.521004988989973	0.676888007784162	HSD17B11	1
GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	1/393	34/18367	0.521004988989973	0.676888007784162	DICER1	1
GO:0035198	miRNA binding	1/393	34/18367	0.521004988989973	0.676888007784162	NEAT1	1
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/393	34/18367	0.521004988989973	0.676888007784162	PTEN	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/393	82/18367	0.526487940067934	0.682640675799505	SDCBP/PICALM	2
GO:0015298	solute:cation antiporter activity	1/393	35/18367	0.531273086918678	0.68609518410456	SLC11A1	1
GO:0042887	amide transmembrane transporter activity	1/393	35/18367	0.531273086918678	0.68609518410456	AQP9	1
GO:0097718	disordered domain specific binding	1/393	36/18367	0.54132161827592	0.697679456224144	HSPA1A	1
GO:0008013	beta-catenin binding	2/393	85/18367	0.545884095797198	0.700767876946006	KDM6B/NUMB	2
GO:0050660	flavin adenine dinucleotide binding	2/393	85/18367	0.545884095797198	0.700767876946006	STEAP4/NQO2	2
GO:0005109	frizzled binding	1/393	37/18367	0.551155266413914	0.703326201415361	SDCBP	1
GO:0030551	cyclic nucleotide binding	1/393	37/18367	0.551155266413914	0.703326201415361	PRKAR1A	1
GO:0043531	ADP binding	1/393	37/18367	0.551155266413914	0.703326201415361	MYH9	1
GO:0042562	hormone binding	2/393	86/18367	0.552225209148383	0.703326201415361	TSPO/NRDC	2
GO:0004520	endodeoxyribonuclease activity	1/393	38/18367	0.560778615039082	0.707258799084378	DICER1	1
GO:0005501	retinoid binding	1/393	38/18367	0.560778615039082	0.707258799084378	IGF2R	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/393	38/18367	0.560778615039082	0.707258799084378	TAF7	1
GO:0019840	isoprenoid binding	1/393	38/18367	0.560778615039082	0.707258799084378	IGF2R	1
GO:0140303	intramembrane lipid transporter activity	1/393	38/18367	0.560778615039082	0.707258799084378	PLSCR1	1
GO:0004402	histone acetyltransferase activity	1/393	39/18367	0.570196150326858	0.715419339991681	NCOA1	1
GO:0043178	alcohol binding	2/393	89/18367	0.570871948913199	0.715419339991681	TSPO/OSBPL8	2
GO:0004175	endopeptidase activity	9/393	430/18367	0.573978022525448	0.715419339991681	MMP25/CTSS/CFLAR/PYCARD/USP15/USP10/MME/PSMB9/NRDC	9
GO:0008022	protein C-terminus binding	4/393	189/18367	0.578303962267477	0.715419339991681	NCF2/CORO1A/SDCBP/VPS4B	4
GO:0045182	translation regulator activity	3/393	140/18367	0.57908394522014	0.715419339991681	ABTB1/EIF1/CPEB4	3
GO:0004177	aminopeptidase activity	1/393	40/18367	0.579412262991717	0.715419339991681	NPEPPS	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/393	40/18367	0.579412262991717	0.715419339991681	CYP4F3	1
GO:0031492	nucleosomal DNA binding	1/393	40/18367	0.579412262991717	0.715419339991681	ACTB	1
GO:0042169	SH2 domain binding	1/393	40/18367	0.579412262991717	0.715419339991681	PTPN6	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/393	40/18367	0.579412262991717	0.715419339991681	PYCARD	1
GO:0044183	protein folding chaperone	1/393	40/18367	0.579412262991717	0.715419339991681	HSPA1A	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/393	41/18367	0.588431250313387	0.720322766398791	ACSL1	1
GO:0030331	estrogen receptor binding	1/393	41/18367	0.588431250313387	0.720322766398791	NCOA1	1
GO:0048487	beta-tubulin binding	1/393	41/18367	0.588431250313387	0.720322766398791	RGS2	1
GO:0061733	peptide-lysine-N-acetyltransferase activity	1/393	41/18367	0.588431250313387	0.720322766398791	NCOA1	1
GO:0043130	ubiquitin binding	2/393	92/18367	0.588950144397157	0.720322766398791	CXCR4/N4BP1	2
GO:0072341	modified amino acid binding	2/393	93/18367	0.59484938698252	0.726165195052246	OSBPL8/MME	2
GO:0008307	structural constituent of muscle	1/393	42/18367	0.597257318120156	0.726363693277709	MYL6	1
GO:0019894	kinesin binding	1/393	42/18367	0.597257318120156	0.726363693277709	ACTB	1
GO:0016410	N-acyltransferase activity	2/393	94/18367	0.600685156518072	0.729161906692669	SAT1/NCOA1	2
GO:0004180	carboxypeptidase activity	1/393	43/18367	0.605894582730185	0.730007067088323	AGTPBP1	1
GO:0005246	calcium channel regulator activity	1/393	43/18367	0.605894582730185	0.730007067088323	PRKCB	1
GO:0016504	peptidase activator activity	1/393	43/18367	0.605894582730185	0.730007067088323	PYCARD	1
GO:0032266	phosphatidylinositol-3-phosphate binding	1/393	43/18367	0.605894582730185	0.730007067088323	NCF4	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/393	44/18367	0.614347072851722	0.737444445519599	MAPK1	1
GO:0051879	Hsp90 protein binding	1/393	44/18367	0.614347072851722	0.737444445519599	HIF1A	1
GO:0003955	NAD(P)H dehydrogenase (quinone) activity	1/393	45/18367	0.62261873144307	0.743236751372078	NQO2	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/393	45/18367	0.62261873144307	0.743236751372078	DICER1	1
GO:0140223	general transcription initiation factor activity	1/393	45/18367	0.62261873144307	0.743236751372078	TAF7	1
GO:0004864	protein phosphatase inhibitor activity	1/393	46/18367	0.630713417533173	0.750131582985226	BOD1L1	1
GO:0140296	general transcription initiation factor binding	1/393	46/18367	0.630713417533173	0.750131582985226	TAF7	1
GO:0005496	steroid binding	2/393	100/18367	0.634369255286047	0.753095244348757	TSPO/OSBPL8	2
GO:0061630	ubiquitin protein ligase activity	6/393	304/18367	0.635826074857465	0.75344225353989	RNF24/RNF149/PELI1/UBE2D1/UBE2D3/CUL3	6
GO:0005319	lipid transporter activity	3/393	154/18367	0.643506842259209	0.761149775030545	TSPO/OSBPL8/PLSCR1	3
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/393	48/18367	0.64638689933304	0.761771081727645	GLUL	1
GO:0070888	E-box binding	1/393	48/18367	0.64638689933304	0.761771081727645	HIF1A	1
GO:0019212	phosphatase inhibitor activity	1/393	49/18367	0.653973009304224	0.767913860290077	BOD1L1	1
GO:0034212	peptide N-acetyltransferase activity	1/393	49/18367	0.653973009304224	0.767913860290077	NCOA1	1
GO:0004518	nuclease activity	4/393	210/18367	0.660763465498499	0.773822270891614	RNASET2/PLSCR1/DICER1/N4BP1	4
GO:0030159	signaling receptor complex adaptor activity	1/393	50/18367	0.661396778675522	0.773822270891614	LRRK2	1
GO:0003713	transcription coactivator activity	5/393	262/18367	0.663131025944702	0.774450855209787	PRKCB/ACTN1/NCOA1/KDM5A/NCOA4	5
GO:0003743	translation initiation factor activity	1/393	51/18367	0.668661672816512	0.779502887049159	EIF1	1
GO:1902936	phosphatidylinositol bisphosphate binding	2/393	107/18367	0.670813595292654	0.780605029054581	SDCBP/PICALM	2
GO:0061659	ubiquitin-like protein ligase activity	6/393	316/18367	0.672474575313035	0.780756948037533	RNF24/RNF149/PELI1/UBE2D1/UBE2D3/CUL3	6
GO:0004879	nuclear receptor activity	1/393	52/18367	0.675771083309148	0.780756948037533	STAT3	1
GO:0016597	amino acid binding	1/393	52/18367	0.675771083309148	0.780756948037533	GLUL	1
GO:0098531	ligand-activated transcription factor activity	1/393	52/18367	0.675771083309148	0.780756948037533	STAT3	1
GO:0008083	growth factor activity	3/393	162/18367	0.677065747282	0.78085835738227	GMFG/OSM/TYMP	3
GO:0060090	molecular adaptor activity	7/393	369/18367	0.678675904652594	0.781322616210371	LRRK2/SDCBP/IQGAP1/STX3/STAT3/STX7/MYH9	7
GO:0005544	calcium-dependent phospholipid binding	1/393	54/18367	0.689536660109078	0.791872808131595	CPNE3	1
GO:0032182	ubiquitin-like protein binding	2/393	111/18367	0.690287888386738	0.791872808131595	CXCR4/N4BP1	2
GO:0030170	pyridoxal phosphate binding	1/393	55/18367	0.6961992545817	0.797240562326301	PYGL	1
GO:0004843	thiol-dependent deubiquitinase	2/393	113/18367	0.699664707550999	0.799049803841749	USP15/USP10	2
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/393	56/18367	0.702719224707814	0.799049803841749	CARD16	1
GO:0050840	extracellular matrix binding	1/393	56/18367	0.702719224707814	0.799049803841749	CTSS	1
GO:0070279	vitamin B6 binding	1/393	56/18367	0.702719224707814	0.799049803841749	PYGL	1
GO:0101005	deubiquitinase activity	2/393	114/18367	0.704264302028375	0.799401760372559	USP15/USP10	2
GO:0004536	deoxyribonuclease activity	1/393	57/18367	0.709099615985725	0.800676180702904	DICER1	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/393	57/18367	0.709099615985725	0.800676180702904	NQO2	1
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/393	57/18367	0.709099615985725	0.800676180702904	MSRB1	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/393	58/18367	0.715343409045125	0.804916844612514	SLC16A3	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/393	58/18367	0.715343409045125	0.804916844612514	ALOX5AP	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/393	60/18367	0.727432806924212	0.817099003611051	LBR	1
GO:0005507	copper ion binding	1/393	61/18367	0.733284060918793	0.822243998985197	S100A12	1
GO:0019783	ubiquitin-like protein-specific protease activity	2/393	125/18367	0.751078022782355	0.840739586055681	USP15/USP10	2
GO:0008242	omega peptidase activity	2/393	126/18367	0.755001459920849	0.843671752277702	USP15/USP10	2
GO:0004519	endonuclease activity	2/393	129/18367	0.766453390231097	0.854991971516413	RNASET2/DICER1	2
GO:0003684	damaged DNA binding	1/393	68/18367	0.770880468663724	0.858450366997297	NBN	1
GO:0001098	basal transcription machinery binding	1/393	70/18367	0.780616461338745	0.866310206665812	TAF7	1
GO:0001099	basal RNA polymerase II transcription machinery binding	1/393	70/18367	0.780616461338745	0.866310206665812	TAF7	1
GO:0031491	nucleosome binding	1/393	71/18367	0.785328585222107	0.87004725109367	ACTB	1
GO:0003678	DNA helicase activity	1/393	72/18367	0.789939749739363	0.87365985996815	DDX3X	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	2/393	136/18367	0.791380187336838	0.873759353595451	CYP4F3/HSD17B11	2
GO:0016829	lyase activity	3/393	196/18367	0.793634741263332	0.874167545656005	ALOX5AP/RNASET2/APMAP	3
GO:0070063	RNA polymerase binding	1/393	73/18367	0.794452112590001	0.874167545656005	ZFP36	1
GO:0099106	ion channel regulator activity	2/393	139/18367	0.801326475926516	0.880234685780061	PRKCB/STX7	2
GO:0034987	immunoglobulin receptor binding	1/393	79/18367	0.819566611533747	0.897661302909681	FGR	1
GO:0016247	channel regulator activity	2/393	145/18367	0.819965734187977	0.897661302909681	PRKCB/STX7	2
GO:0019842	vitamin binding	2/393	148/18367	0.828685950173501	0.905675354328134	PYGL/EGLN1	2
GO:0016757	glycosyltransferase activity	4/393	270/18367	0.832789933560987	0.908625779112915	NAMPT/PYGL/TYMP/ST8SIA4	4
GO:0140098	catalytic activity, acting on RNA	6/393	386/18367	0.837135866214644	0.911389371692614	RNASET2/DDX60L/DDX3X/DICER1/DDX5/N4BP1	6
GO:0030165	PDZ domain binding	1/393	84/18367	0.838140148619947	0.911389371692614	PTEN	1
GO:0003727	single-stranded RNA binding	1/393	87/18367	0.84835565638925	0.920949848462827	DDX3X	1
GO:0008276	protein methyltransferase activity	1/393	88/18367	0.851615843864033	0.922940453902896	PCMTD1	1
GO:0015297	antiporter activity	1/393	89/18367	0.854806115397565	0.924848756960242	SLC11A1	1
GO:0005249	voltage-gated potassium channel activity	1/393	90/18367	0.857927966620278	0.926676785314391	KCNJ15	1
GO:0046943	carboxylic acid transmembrane transporter activity	2/393	163/18367	0.866828350194051	0.934729904292585	AQP9/SLC16A3	2
GO:0005342	organic acid transmembrane transporter activity	2/393	164/18367	0.869072134365392	0.935590134666238	AQP9/SLC16A3	2
GO:0016874	ligase activity	2/393	165/18367	0.871281191970415	0.935639101168763	ACSL1/GLUL	2
GO:0061134	peptidase regulator activity	3/393	230/18367	0.872941789327421	0.935639101168763	SERPINA1/PYCARD/CARD16	3
GO:0008201	heparin binding	2/393	166/18367	0.873455976979803	0.935639101168763	PTPRC/SELL	2
GO:0004867	serine-type endopeptidase inhibitor activity	1/393	98/18367	0.880608896444394	0.941742076032269	SERPINA1	1
GO:0004497	monooxygenase activity	1/393	102/18367	0.890556213277521	0.95080836632105	CYP4F3	1
GO:0004866	endopeptidase inhibitor activity	2/393	180/18367	0.90054998764182	0.959683784910228	SERPINA1/CARD16	2
GO:0051087	chaperone binding	1/393	107/18367	0.901835766963553	0.959683784910228	HLA-B	1
GO:0008514	organic anion transmembrane transporter activity	2/393	185/18367	0.908842207280897	0.96363653084352	SLC2A3/SLC16A3	2
GO:0008094	ATP-dependent activity, acting on DNA	1/393	111/18367	0.910018424026879	0.96363653084352	DDX3X	1
GO:0030594	neurotransmitter receptor activity	1/393	111/18367	0.910018424026879	0.96363653084352	TSPO	1
GO:0030414	peptidase inhibitor activity	2/393	187/18367	0.911974570490063	0.964129978933122	SERPINA1/CARD16	2
GO:0099094	ligand-gated cation channel activity	1/393	113/18367	0.913850925892887	0.964537600412231	KCNJ15	1
GO:0061135	endopeptidase regulator activity	2/393	194/18367	0.922161757992041	0.971724197753828	SERPINA1/CARD16	2
GO:1901681	sulfur compound binding	3/393	265/18367	0.925221113665458	0.97272322487037	PTPRC/SELL/ADGRE2	3
GO:0016758	hexosyltransferase activity	2/393	197/18367	0.926179261345007	0.97272322487037	PYGL/TYMP	2
GO:0005267	potassium channel activity	1/393	121/18367	0.927620138709456	0.97272322487037	KCNJ15	1
GO:0051082	unfolded protein binding	1/393	122/18367	0.929179126185461	0.972781382915846	HSPA1A	1
GO:0003697	single-stranded DNA binding	1/393	123/18367	0.930704618287906	0.972793023182535	NABP1	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/393	124/18367	0.932197332879709	0.972793023182535	HSD17B11	1
GO:0015078	proton transmembrane transporter activity	1/393	130/18367	0.940503600023832	0.979880562343671	SLC11A1	1
GO:0015276	ligand-gated ion channel activity	1/393	143/18367	0.95518180378745	0.989512560926081	KCNJ15	1
GO:0022834	ligand-gated channel activity	1/393	143/18367	0.95518180378745	0.989512560926081	KCNJ15	1
GO:0022843	voltage-gated cation channel activity	1/393	143/18367	0.95518180378745	0.989512560926081	KCNJ15	1
GO:0015293	symporter activity	1/393	144/18367	0.956148306811569	0.989512560926081	SLC16A3	1
GO:0140097	catalytic activity, acting on DNA	2/393	229/18367	0.958450238174604	0.989512560926081	DDX3X/DICER1	2
GO:0052689	carboxylic ester hydrolase activity	1/393	147/18367	0.95892484652342	0.989512560926081	APMAP	1
GO:0015079	potassium ion transmembrane transporter activity	1/393	155/18367	0.965501229917087	0.992318981299832	KCNJ15	1
GO:0015291	secondary active transmembrane transporter activity	2/393	240/18367	0.966021555830056	0.992318981299832	SLC11A1/SLC16A3	2
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	1/393	156/18367	0.96624568503693	0.992318981299832	PCMTD1	1
GO:0005201	extracellular matrix structural constituent	1/393	172/18367	0.976194971477856	0.999921818141513	FGL2	1
GO:0004252	serine-type endopeptidase activity	1/393	174/18367	0.977212239164425	0.999921818141513	CTSS	1
GO:0008236	serine-type peptidase activity	1/393	191/18367	0.984282027033819	0.999921818141513	CTSS	1
GO:0017171	serine hydrolase activity	1/393	195/18367	0.985598085556586	0.999921818141513	CTSS	1
GO:0005244	voltage-gated ion channel activity	1/393	201/18367	0.987368936702646	0.999921818141513	KCNJ15	1
GO:0022832	voltage-gated channel activity	1/393	201/18367	0.987368936702646	0.999921818141513	KCNJ15	1
GO:0008168	methyltransferase activity	1/393	214/18367	0.990495762895669	0.999921818141513	PCMTD1	1
GO:0008509	anion transmembrane transporter activity	2/393	314/18367	0.991544482261134	0.999921818141513	SLC2A3/SLC16A3	2
GO:0016741	transferase activity, transferring one-carbon groups	1/393	225/18367	0.992529868870001	0.999921818141513	PCMTD1	1
GO:0046873	metal ion transmembrane transporter activity	3/393	430/18367	0.995358953290973	0.999921818141513	KCNJ15/SLC25A37/SLC11A1	3
GO:0022853	active ion transmembrane transporter activity	1/393	267/18367	0.997025611645463	0.999921818141513	SLC11A1	1
GO:0022804	active transmembrane transporter activity	2/393	406/18367	0.998598372465575	0.999921818141513	SLC11A1/SLC16A3	2
GO:0005261	cation channel activity	1/393	335/18367	0.99933335054371	0.999921818141513	KCNJ15	1
GO:0022836	gated channel activity	1/393	340/18367	0.999402906326184	0.999921818141513	KCNJ15	1
GO:0015267	channel activity	2/393	480/18367	0.999682413829546	0.999921818141513	AQP9/KCNJ15	2
GO:0022803	passive transmembrane transporter activity	2/393	481/18367	0.999688783136697	0.999921818141513	AQP9/KCNJ15	2
GO:0005216	ion channel activity	1/393	432/18367	0.999921818141513	0.999921818141513	KCNJ15	1