ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0042110 T cell activation 45/380 487/18722 1.57803101640143e-17 6.68296135446005e-14 PTPRC/LCP1/FCER1G/JAML/LYN/AIF1/RAC2/LAPTM5/BCL6/B2M/SLC11A1/SPI1/PELI1/CORO1A/IL6R/HLA-E/WAS/CEBPB/IL1B/PREX1/FGL2/HLA-A/APBB1IP/LILRB2/RAB27A/CLEC7A/TNFRSF1B/MSN/ZFP36L1/EGR1/TNFSF13B/PYCARD/IRF1/NFKBIZ/ZFP36L2/SOS2/STAT3/CD44/PRKAR1A/TGFBR2/CD55/PTPN6/MYH9/PPP3CA/FLOT2 45 GO:0032103 positive regulation of response to external stimulus 41/380 427/18722 1.23765784353456e-16 2.62074048368442e-13 S100A8/S100A12/CXCL8/S100A9/MNDA/PTGS2/CXCR2/LRRK2/C5AR1/LYN/FFAR2/FPR2/OSM/TYROBP/NEAT1/ALOX5AP/AIF1/TMSB4X/RAC2/GPSM3/SPI1/HCK/IL6R/HLA-E/CYBA/CEBPB/IL1B/IL17RA/CXCR4/LY96/CLEC7A/FCN1/STX3/PYCARD/IFI16/NFKBIZ/USP15/PLSCR1/PAK2/PAK1/MAPK1 41 GO:0001819 positive regulation of cytokine production 42/380 467/18722 5.34229162223864e-16 7.54153500672688e-13 MNDA/PTGS2/PTPRC/SORL1/LRRK2/C5AR1/FCER1G/FFAR2/OSM/TYROBP/LTB/AIF1/GPSM3/LAPTM5/B2M/SLC11A1/PELI1/TLR1/NFAM1/IL6R/HLA-E/MBP/FGR/CYBA/CEBPB/IL1B/IRAK3/HLA-A/IL17RA/LILRB2/LY96/CLEC7A/FCN1/EGR1/PYCARD/IRF1/IFI16/STAT3/CD55/DDX3X/HIF1A/HSPA1A 42 GO:0006909 phagocytosis 34/380 308/18722 8.98858167508529e-16 8.80319125816523e-13 PTPRC/FCER1G/LYN/FPR2/TYROBP/NCF2/AIF1/RAC2/SLC11A1/CORO1A/LYST/HCK/ICAM3/CD93/IL2RG/NCF4/FGR/CNN2/ITGB2/CYBA/IL1B/PECAM1/PTEN/RAB27A/CLEC7A/FCN1/PYCARD/CD302/PLSCR1/RHOG/CDC42SE1/MYH9/PAK1/RAB7A 34 GO:0050900 leukocyte migration 37/380 369/18722 1.03933781088137e-15 8.80319125816523e-13 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/SELL/FCER1G/JAML/LYN/FFAR2/FPR2/CD177/CXCR1/ADGRE2/TREM1/AIF1/RAC2/GPSM3/DUSP1/SPI1/CSF3R/CORO1A/LYST/HCK/IL6R/ALOX5/ITGB2/PREX1/PECAM1/CXCR4/MSN/PYCARD/CKLF/RHOG/MYH9/MAPK1 37 GO:0002274 myeloid leukocyte activation 29/380 223/18722 1.69312690971523e-15 1.19506541044067e-12 S100A12/NAMPT/CXCL8/PTPRC/CXCR2/LRRK2/C5AR1/FCER1G/LYN/FPR2/CD177/TYROBP/ADGRE2/AIF1/RAC2/SLC11A1/SPI1/TLR1/CD93/FGR/ITGB2/PREX1/PYCARD/LCP2/PLSCR1/PJA2/IFNGR2/TGFBR2/STXBP3 29 GO:0030595 leukocyte chemotaxis 29/380 230/18722 3.87479098214108e-15 2.34424854419536e-12 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/FCER1G/JAML/LYN/FFAR2/FPR2/CXCR1/ADGRE2/TREM1/AIF1/RAC2/GPSM3/DUSP1/SPI1/CSF3R/CORO1A/LYST/IL6R/ALOX5/ITGB2/PREX1/CXCR4/CKLF/MAPK1 29 GO:0002764 immune response-regulating signaling pathway 40/380 468/18722 1.53299016168738e-14 8.11526666843259e-12 MNDA/PTPRC/FPR1/C5AR1/FCER1G/LYN/FFAR2/FPR2/TYROBP/CTSS/LAPTM5/PELI1/TLR1/HCK/NFAM1/PRKCB/FGR/CYBA/CLEC4E/SEC14L1/IRAK3/ARRB2/HLA-A/LILRB2/LY96/CLEC7A/FCN1/PIK3AP1/LCP2/IRF1/NFKBIZ/USP15/PLSCR1/PJA2/DDX3X/PTPN6/HSPA1A/PAK2/PAK1/MAPK1 40 GO:0002831 regulation of response to biotic stimulus 33/380 327/18722 3.29623356450914e-14 1.55106101618847e-11 MNDA/NCF1/LYN/FFAR2/FPR2/TYROBP/HLA-B/SPI1/TRIB1/HCK/HLA-E/FGR/CYBA/SEC14L1/IRAK3/ARRB2/FGL2/HLA-A/LY96/CLEC7A/FCN1/PYCARD/IRF1/IFI16/CARD16/USP15/PLSCR1/CD55/PTPN6/ADAR/PAK2/PAK1/N4BP1 33 GO:0060326 cell chemotaxis 32/380 310/18722 4.36319976540345e-14 1.84781510064836e-11 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/FCER1G/JAML/LYN/FFAR2/FPR2/CXCR1/ADGRE2/TREM1/AIF1/TMSB4X/RAC2/GPSM3/DUSP1/SPI1/CSF3R/CORO1A/LYST/IL6R/ALOX5/ITGB2/PREX1/ARRB2/CXCR4/CKLF/RHOG/MAPK1 32 GO:0019221 cytokine-mediated signaling pathway 39/380 472/18722 9.94010372589769e-14 3.82693993447061e-11 IFITM2/CXCL8/PTPRC/CXCR2/ACSL1/FCER1G/IFITM1/LILRB3/CSF2RB/OSM/CXCR1/TMSB4X/LAPTM5/SPI1/CSF3R/HCK/IL6R/IL2RG/IL1B/IRAK3/IL17RA/LILRB2/CXCR4/TNFRSF1B/EGR1/TNFSF13B/PYCARD/IRF1/CARD16/JAK1/STAT3/CD44/IFNGR2/PTPN6/HIF1A/ADAR/HSPA1A/IFNAR1/IFITM3 39 GO:0045088 regulation of innate immune response 26/380 218/18722 4.00664885743713e-13 1.41401315927052e-10 MNDA/NCF1/LYN/FFAR2/FPR2/TYROBP/HLA-B/SPI1/HCK/HLA-E/FGR/IRAK3/ARRB2/HLA-A/CLEC7A/FCN1/PYCARD/IRF1/IFI16/USP15/PLSCR1/PTPN6/ADAR/PAK2/PAK1/N4BP1 26 GO:0097529 myeloid leukocyte migration 26/380 220/18722 4.96862751284299e-13 1.53183922474268e-10 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/FCER1G/JAML/LYN/FPR2/CD177/CXCR1/ADGRE2/TREM1/AIF1/RAC2/DUSP1/SPI1/CSF3R/IL6R/ITGB2/PREX1/PECAM1/CKLF/RHOG/MAPK1 26 GO:0072593 reactive oxygen species metabolic process 27/380 239/18722 5.2300501430613e-13 1.53183922474268e-10 SOD2/LRRK2/NCF1/FPR2/CD177/TYROBP/NCF2/RAC2/NCF4/ALOX5/ITGB2/HBA2/CYBA/PREX1/HBA1/CFLAR/TSPO/RAB27A/CLEC7A/HBB/HBG2/STAT3/TGFBR2/NQO2/HIF1A/NFE2L2/CAT 27 GO:0031349 positive regulation of defense response 29/380 278/18722 5.42564070156794e-13 1.53183922474268e-10 S100A8/S100A12/S100A9/MNDA/PTGS2/LRRK2/LYN/FFAR2/FPR2/OSM/TYROBP/NEAT1/ALOX5AP/GPSM3/SPI1/HCK/HLA-E/CYBA/CEBPB/IL1B/IL17RA/CLEC7A/FCN1/PYCARD/IFI16/NFKBIZ/PLSCR1/PAK2/PAK1 29 GO:0007159 leukocyte cell-cell adhesion 33/380 371/18722 1.16108841947877e-12 3.07325591030787e-10 S100A8/S100A9/PTPRC/SELL/LYN/CD177/AIF1/RAC2/LAPTM5/BCL6/B2M/PELI1/CORO1A/HLA-E/ALOX5/ITGB2/CEBPB/IL1B/FGL2/PECAM1/HLA-A/LILRB2/MSN/TNFSF13B/PYCARD/IRF1/NFKBIZ/CD44/PRKAR1A/TGFBR2/CD55/PTPN6/FLOT2 33 GO:0007015 actin filament organization 36/380 441/18722 1.33991585991476e-12 3.33796686278765e-10 LCP1/GMFG/MYO1F/AIF1/TMSB4X/WIPF1/RAC2/PLEK/CORO1A/HCK/MARCKS/MSRB1/WAS/PREX1/MYADM/GPR65/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ZYX/ARPC5/HCLS1/TPM3/SSH2/CAPZA1/RHOG/ACTR3/ACTN1/RICTOR/CUL3/PAK2/PAK1/TMOD3 36 GO:0002237 response to molecule of bacterial origin 32/380 363/18722 3.29669795107181e-12 7.75639767932728e-10 S100A8/CXCL8/S100A9/SOD2/PTGS2/LITAF/C5AR1/LYN/CSF2RB/ALPL/B2M/ZFP36/SLC11A1/SPI1/PELI1/TRIB1/TLR1/FOS/HCK/VIM/CEBPB/IL1B/IRAK3/TSPO/LILRB2/LY96/TNFRSF1B/PYCARD/CARD16/CD55/MAPK1/IFNAR1 32 GO:0008154 actin polymerization or depolymerization 24/380 217/18722 1.66914918243536e-11 3.72044567769144e-09 GMFG/AIF1/TMSB4X/WIPF1/PLEK/CORO1A/HCK/MSRB1/WAS/PREX1/MYADM/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/TMOD3 24 GO:0032496 response to lipopolysaccharide 30/380 343/18722 1.9626906858931e-11 4.15599752737865e-09 S100A8/CXCL8/S100A9/SOD2/PTGS2/LITAF/C5AR1/LYN/CSF2RB/ALPL/ZFP36/SLC11A1/SPI1/PELI1/TRIB1/FOS/HCK/VIM/CEBPB/IL1B/IRAK3/TSPO/LILRB2/LY96/TNFRSF1B/PYCARD/CARD16/CD55/MAPK1/IFNAR1 30 GO:0097530 granulocyte migration 20/380 148/18722 2.18020899491534e-11 4.39675480641261e-09 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/FCER1G/JAML/CD177/CXCR1/ADGRE2/TREM1/RAC2/CSF3R/ITGB2/PREX1/PECAM1/CKLF/RHOG/MAPK1 20 GO:0050670 regulation of lymphocyte proliferation 24/380 225/18722 3.60323933883458e-11 6.77550767848888e-09 MNDA/PTPRC/LST1/LYN/TYROBP/AIF1/RAC2/BCL6/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6 24 GO:0070663 regulation of leukocyte proliferation 25/380 245/18722 3.67973262350045e-11 6.77550767848888e-09 MNDA/PTPRC/LST1/LYN/TYROBP/AIF1/RAC2/BCL6/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6/MAPK1 25 GO:0032944 regulation of mononuclear cell proliferation 24/380 227/18722 4.34413557903056e-11 7.66558924049768e-09 MNDA/PTPRC/LST1/LYN/TYROBP/AIF1/RAC2/BCL6/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6 24 GO:0030041 actin filament polymerization 22/380 190/18722 4.81417860223062e-11 8.15364751370133e-09 GMFG/AIF1/TMSB4X/CORO1A/HCK/MSRB1/WAS/PREX1/MYADM/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/TMOD3 22 GO:1990266 neutrophil migration 18/380 122/18722 5.00578123627472e-11 8.15364751370133e-09 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/FCER1G/JAML/CD177/CXCR1/TREM1/RAC2/CSF3R/ITGB2/PREX1/PECAM1/CKLF/RHOG 18 GO:0030099 myeloid cell differentiation 31/380 381/18722 5.67351332028782e-11 8.89901070793293e-09 EVI2B/LYN/LILRB3/TYROBP/JUNB/BCL6/B2M/ZFP36/SPI1/CSF3R/TRIB1/FOS/KLF2/RASSF2/CEBPB/SNX10/ZFP36L1/LBR/IFI16/PTBP3/HCLS1/STAT3/TGFBR2/ACTN1/PTPN6/HIF1A/ADAR/HSPA1A/MYH9/TET2/TMOD3 31 GO:0002697 regulation of immune effector process 29/380 339/18722 7.34058355905153e-11 1.11026326330654e-08 PTPRC/NCF1/PGLYRP1/LYN/FFAR2/CD177/TYROBP/HLA-B/ADGRE2/RAC2/LAPTM5/BCL6/B2M/SPI1/HLA-E/WAS/FGR/ITGB2/IL1B/IRAK3/ARRB2/FGL2/HLA-A/CLEC7A/TNFRSF1B/NFKBIZ/CD55/PTPN6/STX7 29 GO:0050727 regulation of inflammatory response 31/380 386/18722 7.8810350695936e-11 1.15090287999065e-08 S100A8/S100A12/S100A9/PTGS2/PTPRC/LRRK2/NCF1/PGLYRP1/LYN/FFAR2/FPR2/OSM/NEAT1/ALOX5AP/TMSB4X/GPSM3/BCL6/ZFP36/HCK/HLA-E/FGR/ALOX5/CEBPB/IL1B/IL17RA/TNFRSF1B/PIK3AP1/PYCARD/NFKBIZ/ZYX/RICTOR 31 GO:1903706 regulation of hemopoiesis 30/380 367/18722 1.0466359630617e-10 1.47750110118876e-08 PTPRC/EVI2B/PGLYRP1/LYN/LILRB3/TYROBP/HLA-B/BCL6/B2M/ZFP36/SPI1/CSF3R/TRIB1/FOS/NFAM1/RASSF2/CEBPB/FGL2/LILRB2/ZFP36L1/IRF1/NFKBIZ/ZFP36L2/HCLS1/SOS2/STAT3/TGFBR2/PTPN6/HIF1A/HSPA1A 30 GO:0046651 lymphocyte proliferation 26/380 288/18722 2.25951594936533e-10 3.00816686813436e-08 MNDA/PTPRC/LST1/LYN/TYROBP/AIF1/RAC2/BCL6/SLC11A1/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/MSN/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6 26 GO:0043254 regulation of protein-containing complex assembly 32/380 427/18722 2.27299503613458e-10 3.00816686813436e-08 SORL1/LCP1/GMFG/TMSB4X/PLEK/CORO1A/HCK/WAS/PREX1/MYADM/CLEC7A/MSN/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/RALB/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/BID/RICTOR/DDX3X/NIN/HSPA1A/SH3GLB1/PAK1/TMOD3 32 GO:0008064 regulation of actin polymerization or depolymerization 21/380 187/18722 2.37675119024091e-10 3.05016402747583e-08 GMFG/TMSB4X/PLEK/CORO1A/HCK/WAS/PREX1/MYADM/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/TMOD3 21 GO:0030832 regulation of actin filament length 21/380 188/18722 2.62654267779883e-10 3.27159065896413e-08 GMFG/TMSB4X/PLEK/CORO1A/HCK/WAS/PREX1/MYADM/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/TMOD3 21 GO:0032943 mononuclear cell proliferation 26/380 291/18722 2.83329898553593e-10 3.42829177249848e-08 MNDA/PTPRC/LST1/LYN/TYROBP/AIF1/RAC2/BCL6/SLC11A1/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/MSN/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6 26 GO:0030833 regulation of actin filament polymerization 20/380 171/18722 3.09068580444069e-10 3.63584843939064e-08 GMFG/TMSB4X/CORO1A/HCK/WAS/PREX1/MYADM/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/TMOD3 20 GO:0002683 negative regulation of immune system process 32/380 434/18722 3.42819618724609e-10 3.92389482513168e-08 MNDA/PTPRC/LST1/PGLYRP1/LYN/LILRB3/TYROBP/HLA-B/LAPTM5/BCL6/DUSP1/SPI1/PELI1/TRIB1/HCK/HLA-E/TSC22D3/FGR/CEBPB/SEC14L1/IRAK3/ARRB2/FGL2/HLA-A/LILRB2/IRF1/IFI16/USP15/PRKAR1A/CD55/PTPN6/ADAR 32 GO:0070661 leukocyte proliferation 27/380 318/18722 4.00535668609678e-10 4.39359409901142e-08 MNDA/PTPRC/LST1/LYN/TYROBP/AIF1/RAC2/BCL6/SLC11A1/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/MSN/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6/MAPK1 27 GO:0032271 regulation of protein polymerization 23/380 232/18722 4.04604887512268e-10 4.39359409901142e-08 GMFG/TMSB4X/CORO1A/HCK/WAS/PREX1/MYADM/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/NIN/HSPA1A/PAK1/TMOD3 23 GO:0002366 leukocyte activation involved in immune response 25/380 275/18722 4.37335319187534e-10 4.63028769189802e-08 PTPRC/LCP1/PGLYRP1/FCER1G/LYN/CD177/TYROBP/ADGRE2/RAC2/BCL6/SLC11A1/SPI1/CORO1A/IL6R/FGR/ITGB2/FGL2/APBB1IP/RAB27A/CLEC7A/PYCARD/NFKBIZ/STAT3/STXBP3/NBN 25 GO:0002263 cell activation involved in immune response 25/380 279/18722 5.92472766722691e-10 6.11981016358682e-08 PTPRC/LCP1/PGLYRP1/FCER1G/LYN/CD177/TYROBP/ADGRE2/RAC2/BCL6/SLC11A1/SPI1/CORO1A/IL6R/FGR/ITGB2/FGL2/APBB1IP/RAB27A/CLEC7A/PYCARD/NFKBIZ/STAT3/STXBP3/NBN 25 GO:0071621 granulocyte chemotaxis 17/380 125/18722 6.401120144439e-10 6.45446281230933e-08 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/FCER1G/JAML/CXCR1/ADGRE2/TREM1/RAC2/CSF3R/ITGB2/PREX1/CKLF/MAPK1 17 GO:0032970 regulation of actin filament-based process 30/380 396/18722 6.57441557183315e-10 6.47503487132869e-08 GMFG/TMSB4X/RAC2/PLEK/CORO1A/HCK/WAS/ARHGDIB/CNN2/PREX1/MYADM/IQGAP1/GPR65/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/RHOG/ACTR3/RICTOR/MYH9/PAK2/PAK1/TMOD3 30 GO:0042098 T cell proliferation 21/380 199/18722 7.5581115842459e-10 7.27468239983668e-08 PTPRC/AIF1/RAC2/SLC11A1/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/MSN/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6 21 GO:0050764 regulation of phagocytosis 15/380 95/18722 7.84335932034781e-10 7.38147260481622e-08 PTPRC/FCER1G/FPR2/SLC11A1/HCK/IL2RG/FGR/CNN2/CYBA/IL1B/PTEN/RAB27A/CLEC7A/PYCARD/PLSCR1 15 GO:0032956 regulation of actin cytoskeleton organization 28/380 357/18722 1.14703935771932e-09 1.03578306082493e-07 GMFG/TMSB4X/RAC2/PLEK/CORO1A/HCK/WAS/ARHGDIB/PREX1/MYADM/IQGAP1/GPR65/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/RHOG/ACTR3/RICTOR/PAK2/PAK1/TMOD3 28 GO:0097193 intrinsic apoptotic signaling pathway 25/380 288/18722 1.14951130717289e-09 1.03578306082493e-07 S100A8/S100A9/SOD2/PTGS2/BCL2A1/LRRK2/IVNS1ABP/PLAUR/CDKN2D/MCL1/CEBPB/TNFRSF1B/PYCARD/IFI16/CD44/BID/DDX3X/GRINA/HIF1A/DDX5/HSPA1A/CUL3/PPP1R15A/NBN/NFE2L2 25 GO:0002703 regulation of leukocyte mediated immunity 22/380 226/18722 1.38447260201722e-09 1.22150863948811e-07 PTPRC/LYN/CD177/TYROBP/HLA-B/ADGRE2/RAC2/BCL6/B2M/SPI1/HLA-E/WAS/FGR/ITGB2/IL1B/ARRB2/HLA-A/CLEC7A/TNFRSF1B/CD55/PTPN6/STX7 22 GO:0051258 protein polymerization 25/380 296/18722 2.02595365369383e-09 1.75100280069252e-07 GMFG/AIF1/TMSB4X/CORO1A/HCK/MSRB1/WAS/PREX1/MYADM/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/NIN/HSPA1A/PAK1/TMOD3 25 GO:0042129 regulation of T cell proliferation 19/380 171/18722 2.06925801777211e-09 1.75266154105298e-07 PTPRC/AIF1/RAC2/PELI1/CORO1A/HLA-E/CEBPB/IL1B/HLA-A/LILRB2/TNFRSF1B/TNFSF13B/PYCARD/IRF1/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6 19 GO:0030593 neutrophil chemotaxis 15/380 103/18722 2.50385737602228e-09 2.07918352695183e-07 S100A8/S100A12/CXCL8/S100A9/CXCR2/C5AR1/FCER1G/JAML/CXCR1/TREM1/RAC2/CSF3R/ITGB2/PREX1/CKLF 15 GO:0110053 regulation of actin filament organization 24/380 277/18722 2.58547495454072e-09 2.1056704677846e-07 GMFG/TMSB4X/PLEK/CORO1A/HCK/WAS/PREX1/MYADM/GPR65/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/PAK2/PAK1/TMOD3 24 GO:0022407 regulation of cell-cell adhesion 31/380 448/18722 3.02763504001154e-09 2.41925177253752e-07 PTPRC/LYN/AIF1/LAPTM5/BCL6/B2M/SPI1/PELI1/CORO1A/PLAUR/HLA-E/MBP/ALOX5/ITGB2/CEBPB/IL1B/FGL2/MYADM/HLA-A/LILRB2/TNFSF13B/PYCARD/IRF1/NFKBIZ/JAK1/CD44/PRKAR1A/TGFBR2/CD55/PTPN6/FLOT2 31 GO:0031334 positive regulation of protein-containing complex assembly 22/380 237/18722 3.37969754929166e-09 2.6478113577909e-07 LCP1/GMFG/PLEK/CORO1A/HCK/WAS/CLEC7A/MSN/ACTR2/PYCARD/CDC42EP3/ARPC3/VASP/ARPC5/ACTR3/BID/RICTOR/DDX3X/NIN/HSPA1A/SH3GLB1/PAK1 22 GO:0002253 activation of immune response 28/380 375/18722 3.4387160490791e-09 2.6478113577909e-07 MNDA/PTPRC/FPR1/C5AR1/FCER1G/LYN/FFAR2/FPR2/TYROBP/LAPTM5/HCK/NFAM1/PRKCB/FGR/IL1B/HLA-A/CLEC7A/FCN1/PYCARD/LCP2/IFI16/NFKBIZ/PLSCR1/CD55/PTPN6/PAK2/PAK1/MAPK1 28 GO:0050863 regulation of T cell activation 26/380 329/18722 3.90885638237e-09 2.95607263916731e-07 PTPRC/LYN/AIF1/RAC2/LAPTM5/BCL6/B2M/PELI1/CORO1A/HLA-E/CEBPB/IL1B/FGL2/HLA-A/LILRB2/TNFRSF1B/TNFSF13B/PYCARD/IRF1/NFKBIZ/SOS2/PRKAR1A/TGFBR2/CD55/PTPN6/FLOT2 26 GO:2001233 regulation of apoptotic signaling pathway 27/380 356/18722 4.73090685116812e-09 3.5149807920521e-07 S100A8/G0S2/S100A9/SOD2/PTGS2/PTPRC/LRRK2/IVNS1ABP/PLAUR/CDKN2D/MCL1/IL1B/ARRB2/CFLAR/PTEN/STK4/PYCARD/TNFSF10/CD44/BID/DDX3X/GRINA/HIF1A/HSPA1A/PAK2/PHIP/NFE2L2 27 GO:0002218 activation of innate immune response 11/380 52/18722 5.97522073598967e-09 4.35434677046588e-07 MNDA/LYN/FFAR2/TYROBP/HCK/CLEC7A/FCN1/PYCARD/IFI16/PAK2/PAK1 11 GO:1903037 regulation of leukocyte cell-cell adhesion 26/380 336/18722 6.06626822803984e-09 4.35434677046588e-07 PTPRC/LYN/AIF1/LAPTM5/BCL6/B2M/PELI1/CORO1A/HLA-E/ALOX5/ITGB2/CEBPB/IL1B/FGL2/HLA-A/LILRB2/TNFSF13B/PYCARD/IRF1/NFKBIZ/CD44/PRKAR1A/TGFBR2/CD55/PTPN6/FLOT2 26 GO:0045785 positive regulation of cell adhesion 30/380 437/18722 6.59765703455188e-09 4.60704236198375e-07 PTPRC/LYN/AIF1/BCL6/B2M/CORO1A/PLAUR/HLA-E/ALOX5/ITGB2/IL1B/PREX1/MYADM/HLA-A/APBB1IP/LILRB2/IQGAP1/STK4/TNFSF13B/STX3/PYCARD/NFKBIZ/JAK1/CD44/TGFBR2/CD55/PTPN6/PPP3CA/DOCK5/FLOT2 30 GO:0071216 cellular response to biotic stimulus 22/380 246/18722 6.74655415439901e-09 4.60704236198375e-07 CXCL8/LITAF/LYN/ZFP36/SPI1/TRIB1/TLR1/HCK/TXNIP/VIM/CEBPB/IL1B/TSPO/LILRB2/LY96/CLEC7A/TNFRSF1B/PYCARD/CARD16/BID/CD55/MAPK1 22 GO:0002429 immune response-activating cell surface receptor signaling pathway 24/380 291/18722 6.85345144757913e-09 4.60704236198375e-07 MNDA/PTPRC/FPR1/C5AR1/FCER1G/LYN/FFAR2/FPR2/TYROBP/LAPTM5/HCK/NFAM1/PRKCB/FGR/HLA-A/CLEC7A/FCN1/LCP2/NFKBIZ/PLSCR1/PTPN6/PAK2/PAK1/MAPK1 24 GO:0002757 immune response-activating signal transduction 24/380 291/18722 6.85345144757913e-09 4.60704236198375e-07 MNDA/PTPRC/FPR1/C5AR1/FCER1G/LYN/FFAR2/FPR2/TYROBP/LAPTM5/HCK/NFAM1/PRKCB/FGR/HLA-A/CLEC7A/FCN1/LCP2/NFKBIZ/PLSCR1/PTPN6/PAK2/PAK1/MAPK1 24 GO:0002768 immune response-regulating cell surface receptor signaling pathway 25/380 315/18722 7.2007806930805e-09 4.75067089452611e-07 MNDA/PTPRC/FPR1/C5AR1/FCER1G/LYN/FFAR2/FPR2/TYROBP/LAPTM5/HCK/NFAM1/PRKCB/FGR/HLA-A/LILRB2/CLEC7A/FCN1/LCP2/NFKBIZ/PLSCR1/PTPN6/PAK2/PAK1/MAPK1 25 GO:0032635 interleukin-6 production 18/380 165/18722 7.40364295250822e-09 4.75067089452611e-07 TYROBP/HLA-B/AIF1/TLR1/KLF2/IL6R/MBP/CYBA/CEBPB/IL1B/IRAK3/ARRB2/IL17RA/LILRB2/CLEC7A/PYCARD/STAT3/PTPN6 18 GO:0032675 regulation of interleukin-6 production 18/380 165/18722 7.40364295250822e-09 4.75067089452611e-07 TYROBP/HLA-B/AIF1/TLR1/KLF2/IL6R/MBP/CYBA/CEBPB/IL1B/IRAK3/ARRB2/IL17RA/LILRB2/CLEC7A/PYCARD/STAT3/PTPN6 18 GO:0002833 positive regulation of response to biotic stimulus 18/380 168/18722 9.86194758143662e-09 6.18784505312902e-07 MNDA/LYN/FFAR2/FPR2/TYROBP/SPI1/HCK/HLA-E/CYBA/LY96/CLEC7A/FCN1/PYCARD/IFI16/USP15/PLSCR1/PAK2/PAK1 18 GO:0002758 innate immune response-activating signal transduction 8/380 23/18722 1.00548035230968e-08 6.18784505312902e-07 LYN/FFAR2/TYROBP/HCK/CLEC7A/FCN1/PAK2/PAK1 8 GO:0001906 cell killing 19/380 188/18722 1.00817310192657e-08 6.18784505312902e-07 S100A12/PTPRC/PGLYRP1/TYROBP/HLA-B/TREM1/B2M/SPI1/CORO1A/LYST/HLA-E/ARRB2/HLA-A/RAB27A/CLEC7A/LYZ/CD55/PTPN6/STX7 19 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 14/380 98/18722 1.10477300078203e-08 6.68387665473126e-07 SOD2/PTGS2/LRRK2/IVNS1ABP/PLAUR/CDKN2D/MCL1/CD44/BID/DDX3X/GRINA/HIF1A/HSPA1A/NFE2L2 14 GO:0042060 wound healing 29/380 422/18722 1.16272043013746e-08 6.93538172060865e-07 S100A8/FCER1G/JAML/LYN/SERPINA1/SLC11A1/PLEK/ACTB/PLAUR/WAS/CNN2/ALOX5/CFLAR/PTEN/CXCR4/RAB27A/CLEC7A/HBB/JMJD1C/PLSCR1/CD44/TGFBR2/PTPN6/HIF1A/STXBP3/MYH9/PPP3CA/PAK1/NFE2L2 29 GO:0002221 pattern recognition receptor signaling pathway 18/380 172/18722 1.4311631900371e-08 8.20700949989084e-07 LYN/FFAR2/CTSS/PELI1/TLR1/CYBA/CLEC4E/SEC14L1/IRAK3/ARRB2/LY96/FCN1/PIK3AP1/IRF1/USP15/PJA2/DDX3X/HSPA1A 18 GO:1903131 mononuclear cell differentiation 29/380 426/18722 1.43306100254389e-08 8.20700949989084e-07 PTPRC/PGLYRP1/FCER1G/LYN/HLA-B/BCL6/B2M/SPI1/NFAM1/IL6R/CEBPB/IL1B/PREX1/FGL2/LILRB2/KLF6/ZFP36L1/EGR1/TNFSF13B/IRF1/IFI16/NFKBIZ/ZFP36L2/NFIL3/SOS2/STAT3/TGFBR2/PTPN6/MYH9 29 GO:1902105 regulation of leukocyte differentiation 23/380 279/18722 1.434046524184e-08 8.20700949989084e-07 PTPRC/EVI2B/PGLYRP1/LYN/LILRB3/TYROBP/HLA-B/BCL6/TRIB1/FOS/NFAM1/RASSF2/CEBPB/FGL2/LILRB2/ZFP36L1/IRF1/NFKBIZ/ZFP36L2/HCLS1/SOS2/TGFBR2/PTPN6 23 GO:0050777 negative regulation of immune response 19/380 194/18722 1.68907154989442e-08 9.5376240184038e-07 PTPRC/PGLYRP1/LYN/HLA-B/BCL6/SPI1/HCK/HLA-E/FGR/SEC14L1/IRAK3/ARRB2/FGL2/HLA-A/IFI16/USP15/CD55/PTPN6/ADAR 19 GO:2000377 regulation of reactive oxygen species metabolic process 17/380 157/18722 2.17345269176378e-08 1.21112791442363e-06 SOD2/FPR2/CD177/TYROBP/RAC2/ALOX5/ITGB2/CYBA/CFLAR/TSPO/RAB27A/CLEC7A/STAT3/TGFBR2/NQO2/HIF1A/NFE2L2 17 GO:0001774 microglial cell activation 10/380 47/18722 2.79742094454089e-08 1.53858151949749e-06 NAMPT/PTPRC/LRRK2/C5AR1/FPR2/TYROBP/AIF1/TLR1/ITGB2/IFNGR2 10 GO:0006801 superoxide metabolic process 12/380 74/18722 2.90718051253513e-08 1.56323580878677e-06 SOD2/NCF1/FPR2/CD177/TYROBP/NCF2/NCF4/ITGB2/CYBA/PREX1/CLEC7A/NFE2L2 12 GO:0002443 leukocyte mediated immunity 29/380 440/18722 2.91607152052314e-08 1.56323580878677e-06 PTPRC/FCER1G/LYN/CD177/TYROBP/HLA-B/ADGRE2/TREM1/RAC2/BCL6/B2M/SPI1/CORO1A/LYST/HLA-E/WAS/FGR/ITGB2/IL1B/ARRB2/HLA-A/RAB27A/CLEC7A/TNFRSF1B/CD55/PTPN6/STX7/STXBP3/NBN 29 GO:0042119 neutrophil activation 9/380 36/18722 3.08547211778242e-08 1.61581863728273e-06 CXCL8/CXCR2/FCER1G/CD177/TYROBP/SPI1/ITGB2/PREX1/STXBP3 9 GO:0019882 antigen processing and presentation 14/380 106/18722 3.09046775961985e-08 1.61581863728273e-06 FCER1G/CTSS/HLA-B/HLA-C/B2M/SLC11A1/HLA-E/WAS/FGL2/HLA-A/LILRB2/RAB27A/PYCARD/RAB8B 14 GO:0009615 response to virus 26/380 367/18722 3.69348049536347e-08 1.90754754852003e-06 IFITM2/PTPRC/IFITM1/MX2/LYST/IVNS1ABP/ITGAX/APOBEC3A/FGR/SEC14L1/IRAK3/FGL2/IL17RA/CXCR4/PYCARD/IRF1/IFI16/BNIP3L/USP15/PLSCR1/IFNGR2/DDX3X/HIF1A/ADAR/IFNAR1/IFITM3 26 GO:0002819 regulation of adaptive immune response 18/380 183/18722 3.77488737410872e-08 1.9261021722109e-06 PTPRC/HLA-B/BCL6/B2M/SLC11A1/HLA-E/WAS/IL1B/HLA-A/CLEC7A/TNFRSF1B/TNFSF13B/PYCARD/IRF1/NFKBIZ/CD55/PTPN6/STX7 18 GO:0051495 positive regulation of cytoskeleton organization 20/380 226/18722 3.94623228543274e-08 1.97211119947825e-06 GMFG/PLEK/CORO1A/HCK/WAS/GPR65/ACTR2/PYCARD/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/ACTR3/RICTOR/NIN/HSPA1A/VPS4B/PAK1/KATNBL1 20 GO:2000379 positive regulation of reactive oxygen species metabolic process 12/380 76/18722 3.96261040734341e-08 1.97211119947825e-06 SOD2/FPR2/CD177/TYROBP/ITGB2/CYBA/TSPO/RAB27A/CLEC7A/TGFBR2/NQO2/NFE2L2 12 GO:0045730 respiratory burst 9/380 37/18722 4.00475946056976e-08 1.97211119947825e-06 NCF1/NCF2/RAC2/SLC11A1/HCK/NCF4/CYBA/CLEC7A/CD55 9 GO:2001242 regulation of intrinsic apoptotic signaling pathway 17/380 164/18722 4.17204260125251e-08 2.03087361106947e-06 S100A8/S100A9/SOD2/PTGS2/LRRK2/IVNS1ABP/PLAUR/CDKN2D/MCL1/PYCARD/CD44/BID/DDX3X/GRINA/HIF1A/HSPA1A/NFE2L2 17 GO:0002526 acute inflammatory response 14/380 112/18722 6.29163499584685e-08 3.0278493417513e-06 S100A8/PTGS2/CXCR2/FFAR2/OSM/SERPINA1/ALOX5AP/TREM1/IL6R/HLA-E/CEBPB/IL1B/PLSCR1/STAT3 14 GO:0045089 positive regulation of innate immune response 15/380 131/18722 6.99437302083777e-08 3.32822131946607e-06 MNDA/LYN/FFAR2/FPR2/TYROBP/SPI1/HCK/HLA-E/CLEC7A/FCN1/PYCARD/IFI16/PLSCR1/PAK2/PAK1 15 GO:0002699 positive regulation of immune effector process 20/380 235/18722 7.54890974080355e-08 3.55218141692256e-06 PTPRC/LYN/FFAR2/CD177/TYROBP/HLA-B/ADGRE2/RAC2/LAPTM5/B2M/SPI1/HLA-E/FGR/ITGB2/IL1B/HLA-A/CLEC7A/NFKBIZ/CD55/STX7 20 GO:0032535 regulation of cellular component size 26/380 382/18722 8.22134500948197e-08 3.78449957773437e-06 GMFG/TMSB4X/PLEK/CORO1A/HCK/WAS/PREX1/MYADM/PTEN/MSN/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/PICALM/SSH2/CAPZA1/ACTR3/RICTOR/PPP1R15A/PAK1/TMOD3 26 GO:1902903 regulation of supramolecular fiber organization 26/380 382/18722 8.22134500948197e-08 3.78449957773437e-06 GMFG/TMSB4X/PLEK/CORO1A/HCK/WAS/PREX1/MYADM/GPR65/ACTR2/PYCARD/COTL1/CDC42EP3/ARPC3/VASP/ARPC5/HCLS1/SSH2/CAPZA1/ACTR3/RICTOR/NIN/HSPA1A/PAK2/PAK1/TMOD3 26 GO:0022409 positive regulation of cell-cell adhesion 22/380 284/18722 8.9879357397965e-08 4.09289331806862e-06 PTPRC/LYN/AIF1/BCL6/B2M/CORO1A/PLAUR/HLA-E/ALOX5/ITGB2/IL1B/HLA-A/LILRB2/TNFSF13B/PYCARD/NFKBIZ/JAK1/CD44/TGFBR2/CD55/PTPN6/FLOT2 22 GO:1903039 positive regulation of leukocyte cell-cell adhesion 20/380 239/18722 9.96710141730793e-08 4.49049728747862e-06 PTPRC/LYN/AIF1/BCL6/B2M/CORO1A/HLA-E/ALOX5/ITGB2/IL1B/HLA-A/LILRB2/TNFSF13B/PYCARD/NFKBIZ/CD44/TGFBR2/CD55/PTPN6/FLOT2 20 GO:0070486 leukocyte aggregation 6/380 13/18722 1.02271738639071e-07 4.55916645406806e-06 S100A8/S100A9/RAC2/IL1B/MSN/CD44 6 GO:0071674 mononuclear cell migration 18/380 196/18722 1.08339341860068e-07 4.77934492476448e-06 S100A12/CXCR2/C5AR1/JAML/LYN/FPR2/CXCR1/AIF1/DUSP1/SPI1/IL6R/ALOX5/PECAM1/CXCR4/MSN/PYCARD/CKLF/MAPK1 18 GO:0045936 negative regulation of phosphate metabolic process 28/380 441/18722 1.11156574923307e-07 4.85307314227017e-06 RGS2/PTPRC/SORL1/LRRK2/LYN/CDA/DUSP1/PLEK/TRIB1/CDKN2D/RASSF2/MIDN/IL1B/IRAK3/PPP2R5A/ARRB2/MYADM/PTEN/PYCARD/BOD1L1/STAT3/PRKAR1A/UBE2B/PTPN6/TAF7/ADAR/PAK2/PPP1R15A 28 GO:0010563 negative regulation of phosphorus metabolic process 28/380 442/18722 1.16497218001416e-07 5.03434406363263e-06 RGS2/PTPRC/SORL1/LRRK2/LYN/CDA/DUSP1/PLEK/TRIB1/CDKN2D/RASSF2/MIDN/IL1B/IRAK3/PPP2R5A/ARRB2/MYADM/PTEN/PYCARD/BOD1L1/STAT3/PRKAR1A/UBE2B/PTPN6/TAF7/ADAR/PAK2/PPP1R15A 28 GO:0097191 extrinsic apoptotic signaling pathway 19/380 219/18722 1.18473637852142e-07 5.06803895256386e-06 G0S2/BCL2A1/PTPRC/TNFRSF10C/SPI1/IL6R/MCL1/IL1B/CFLAR/PTEN/STK4/TNFRSF1B/PYCARD/TNFSF10/BID/DDX3X/HSPA1A/PAK2/PHIP 19 GO:0002262 myeloid cell homeostasis 16/380 157/18722 1.32670286492261e-07 5.61858663294725e-06 CXCR2/LYN/HCAR2/BCL6/B2M/ZFP36/SPI1/KLF2/ZFP36L1/PTBP3/HCLS1/STAT3/HIF1A/ADAR/HSPA1A/TMOD3 16 GO:0071219 cellular response to molecule of bacterial origin 19/380 221/18722 1.36720486529734e-07 5.7327847569646e-06 CXCL8/LITAF/LYN/ZFP36/SPI1/TRIB1/TLR1/HCK/VIM/CEBPB/IL1B/TSPO/LILRB2/LY96/TNFRSF1B/PYCARD/CARD16/CD55/MAPK1 19 GO:0032273 positive regulation of protein polymerization 15/380 138/18722 1.40283068438056e-07 5.82449798858007e-06 GMFG/CORO1A/HCK/WAS/ACTR2/PYCARD/CDC42EP3/ARPC3/VASP/ARPC5/ACTR3/RICTOR/NIN/HSPA1A/PAK1 15 GO:0030218 erythrocyte differentiation 14/380 120/18722 1.51368006353878e-07 6.22372336804535e-06 LYN/BCL6/B2M/ZFP36/SPI1/KLF2/ZFP36L1/PTBP3/HCLS1/STAT3/HIF1A/ADAR/HSPA1A/TMOD3 14 GO:0036230 granulocyte activation 9/380 43/18722 1.63024996452305e-07 6.638565961303e-06 CXCL8/CXCR2/FCER1G/CD177/TYROBP/SPI1/ITGB2/PREX1/STXBP3 9 GO:0002220 innate immune response activating cell surface receptor signaling pathway 7/380 22/18722 1.76111993971192e-07 7.1031837568381e-06 LYN/FFAR2/TYROBP/CLEC7A/FCN1/PAK2/PAK1 7 GO:0032722 positive regulation of chemokine production 11/380 71/18722 1.79374245521223e-07 7.1665087715319e-06 FFAR2/AIF1/IL6R/MBP/IL1B/IL17RA/CLEC7A/EGR1/PYCARD/DDX3X/HIF1A 11 GO:0034341 response to interferon-gamma 15/380 141/18722 1.86514838150297e-07 7.34255302924112e-06 IFITM2/IFITM1/AIF1/SLC11A1/HCK/WAS/VIM/ACTR2/IRF1/JAK1/ZYX/IFNGR2/ACTR3/STXBP3/IFITM3 15 GO:0048872 homeostasis of number of cells 21/380 272/18722 1.87248105586314e-07 7.34255302924112e-06 CXCR2/LYN/HCAR2/BCL6/B2M/ZFP36/SPI1/CORO1A/KLF2/RASSF2/TSC22D3/ZFP36L1/TNFSF13B/PTBP3/HCLS1/SOS2/STAT3/HIF1A/ADAR/HSPA1A/TMOD3 21 GO:0042554 superoxide anion generation 9/380 44/18722 2.01306751477288e-07 7.8214136927185e-06 NCF1/FPR2/CD177/TYROBP/NCF2/NCF4/ITGB2/CYBA/CLEC7A 9 GO:0050729 positive regulation of inflammatory response 15/380 142/18722 2.04745751953377e-07 7.882711450205e-06 S100A8/S100A12/S100A9/PTGS2/LRRK2/FFAR2/OSM/NEAT1/ALOX5AP/GPSM3/HLA-E/CEBPB/IL1B/IL17RA/NFKBIZ 15 GO:0001909 leukocyte mediated cytotoxicity 14/380 124/18722 2.28569914123634e-07 8.72066293976206e-06 PTPRC/TYROBP/HLA-B/TREM1/B2M/SPI1/CORO1A/LYST/HLA-E/ARRB2/HLA-A/RAB27A/PTPN6/STX7 14 GO:0042116 macrophage activation 13/380 106/18722 2.34087292607467e-07 8.85142575171983e-06 NAMPT/PTPRC/LRRK2/C5AR1/FPR2/TYROBP/AIF1/SLC11A1/TLR1/CD93/ITGB2/PJA2/IFNGR2 13 GO:0043299 leukocyte degranulation 11/380 73/18722 2.40400581748278e-07 9.00970321861907e-06 LYN/CD177/ADGRE2/RAC2/SPI1/CORO1A/HCK/FGR/ITGB2/RAB27A/STXBP3 11 GO:0006887 exocytosis 24/380 352/18722 2.53475601237675e-07 9.41639623896101e-06 LRRK2/LYN/CD177/ADGRE2/RAC2/SPI1/PLEK/CORO1A/HCK/PRKCB/FGR/ITGB2/SDCBP/RAB27A/STX3/TNFAIP2/RALB/RAB11FIP1/RAB8B/STXBP3/MYH9/VPS4B/PAK1/RAB7A 24 GO:0002695 negative regulation of leukocyte activation 17/380 187/18722 2.83365445971539e-07 1.0407317200217e-05 MNDA/PTPRC/LST1/PGLYRP1/LYN/TYROBP/LAPTM5/BCL6/SPI1/PELI1/FGR/CEBPB/FGL2/LILRB2/IRF1/PRKAR1A/PTPN6 17 GO:0071222 cellular response to lipopolysaccharide 18/380 209/18722 2.85064650584455e-07 1.0407317200217e-05 CXCL8/LITAF/LYN/ZFP36/SPI1/TRIB1/HCK/VIM/CEBPB/IL1B/TSPO/LILRB2/LY96/TNFRSF1B/PYCARD/CARD16/CD55/MAPK1 18 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 16/380 168/18722 3.37738186056356e-07 1.22249676747749e-05 PTPRC/HLA-B/BCL6/B2M/SLC11A1/HLA-E/WAS/IL1B/HLA-A/CLEC7A/TNFRSF1B/TNFSF13B/NFKBIZ/CD55/PTPN6/STX7 16 GO:0071900 regulation of protein serine/threonine kinase activity 24/380 359/18722 3.62924937473797e-07 1.30253144932333e-05 S100A12/RGS2/SORL1/LRRK2/ACSL1/LYN/DUSP1/ACTB/TRIB1/CDKN2D/IL1B/IRAK3/PTEN/IQGAP1/STK4/PYCARD/DAZAP2/CCNL1/RALB/PRKAR1A/RICTOR/DDX3X/PTPN6/PAK1 24 GO:0034101 erythrocyte homeostasis 14/380 129/18722 3.7399505968454e-07 1.3309824182891e-05 LYN/BCL6/B2M/ZFP36/SPI1/KLF2/ZFP36L1/PTBP3/HCLS1/STAT3/HIF1A/ADAR/HSPA1A/TMOD3 14 GO:0032755 positive regulation of interleukin-6 production 12/380 93/18722 3.90329519423706e-07 1.37753792896616e-05 TYROBP/AIF1/TLR1/IL6R/MBP/CYBA/IL1B/IL17RA/LILRB2/CLEC7A/PYCARD/STAT3 12 GO:0070665 positive regulation of leukocyte proliferation 15/380 150/18722 4.19528249721512e-07 1.46834887402529e-05 PTPRC/LYN/AIF1/BCL6/PELI1/CORO1A/HLA-E/IL1B/HLA-A/LILRB2/TNFSF13B/PYCARD/TGFBR2/CD55/MAPK1 15 GO:0002821 positive regulation of adaptive immune response 13/380 112/18722 4.47869371942203e-07 1.55469409030757e-05 PTPRC/HLA-B/B2M/SLC11A1/HLA-E/IL1B/HLA-A/CLEC7A/TNFSF13B/PYCARD/NFKBIZ/CD55/STX7 13 GO:0007568 aging 23/380 339/18722 4.93178026368506e-07 1.69805605013872e-05 NAMPT/SOD2/PTGS2/BCL2A1/LITAF/LRRK2/BCL6/B2M/SPI1/FOS/TSPO/PTEN/TNFRSF1B/PICALM/STAT3/TGFBR2/YPEL3/MME/PPP3CA/BAZ2B/MAPK1/NFE2L2/CAT 23 GO:0008360 regulation of cell shape 15/380 154/18722 5.89826480965407e-07 2.01444769910363e-05 LST1/PLXNC1/RAC2/CORO1A/HCK/FMNL1/FGR/ARHGAP15/ITGB2/MSN/CDC42EP3/RHOG/CDC42SE1/MYH9/PHIP 15 GO:0045862 positive regulation of proteolysis 24/380 372/18722 6.88968021905933e-07 2.3342236582173e-05 S100A8/S100A9/LRRK2/LYN/LAPTM5/TRIB1/MBP/IL1B/CFLAR/PTEN/AGTPBP1/CLEC7A/TNFRSF1B/PYCARD/TNFSF10/IFI16/PICALM/STAT3/BID/DDX3X/HSPA1A/MYH9/NRDC/NFE2L2 24 GO:0002367 cytokine production involved in immune response 12/380 98/18722 6.9489465099146e-07 2.33561813249907e-05 FFAR2/TREM1/LAPTM5/BCL6/B2M/HLA-E/IL1B/IRAK3/HLA-A/CLEC7A/TNFRSF1B/CD55 12 GO:0051250 negative regulation of lymphocyte activation 15/380 157/18722 7.55982425413416e-07 2.50865575985459e-05 MNDA/LST1/PGLYRP1/LYN/TYROBP/LAPTM5/BCL6/PELI1/FGR/CEBPB/FGL2/LILRB2/IRF1/PRKAR1A/PTPN6 15 GO:0030098 lymphocyte differentiation 24/380 374/18722 7.5822417299029e-07 2.50865575985459e-05 PTPRC/PGLYRP1/FCER1G/BCL6/B2M/SPI1/NFAM1/IL6R/IL1B/PREX1/FGL2/LILRB2/KLF6/ZFP36L1/EGR1/TNFSF13B/IRF1/NFKBIZ/ZFP36L2/NFIL3/SOS2/STAT3/TGFBR2/PTPN6 24 GO:0009595 detection of biotic stimulus 8/380 38/18722 7.68386490320962e-07 2.51021113790561e-05 PGLYRP1/HLA-B/TLR1/HLA-A/TSPO/LY96/CLEC7A/PAK1 8 GO:0030838 positive regulation of actin filament polymerization 12/380 99/18722 7.76476172528065e-07 2.51021113790561e-05 GMFG/CORO1A/HCK/WAS/ACTR2/PYCARD/CDC42EP3/ARPC3/VASP/ARPC5/ACTR3/RICTOR 12 GO:0032602 chemokine production 12/380 99/18722 7.76476172528065e-07 2.51021113790561e-05 FFAR2/TREM1/AIF1/IL6R/MBP/IL1B/IL17RA/CLEC7A/EGR1/PYCARD/DDX3X/HIF1A 12 GO:2001234 negative regulation of apoptotic signaling pathway 18/380 224/18722 7.92567779223557e-07 2.54282162500891e-05 SOD2/PTGS2/LRRK2/IVNS1ABP/PLAUR/CDKN2D/MCL1/IL1B/ARRB2/CFLAR/CD44/BID/DDX3X/GRINA/HIF1A/HSPA1A/PHIP/NFE2L2 18 GO:0050766 positive regulation of phagocytosis 10/380 66/18722 8.08992564957692e-07 2.57600264104949e-05 PTPRC/FCER1G/FPR2/SLC11A1/IL2RG/CYBA/IL1B/RAB27A/CLEC7A/PYCARD 10 GO:0032640 tumor necrosis factor production 16/380 181/18722 9.25266390703463e-07 2.90259493676235e-05 PTPRC/LRRK2/TYROBP/ZFP36/TLR1/HLA-E/CYBA/IRAK3/ARRB2/TSPO/LY96/CLEC7A/PYCARD/STAT3/PTPN6/DICER1 16 GO:0032680 regulation of tumor necrosis factor production 16/380 181/18722 9.25266390703463e-07 2.90259493676235e-05 PTPRC/LRRK2/TYROBP/ZFP36/TLR1/HLA-E/CYBA/IRAK3/ARRB2/TSPO/LY96/CLEC7A/PYCARD/STAT3/PTPN6/DICER1 16 GO:0002283 neutrophil activation involved in immune response 6/380 18/18722 1.01508830162167e-06 3.1609551157116e-05 FCER1G/CD177/TYROBP/SPI1/ITGB2/STXBP3 6 GO:0036294 cellular response to decreased oxygen levels 15/380 161/18722 1.04276717113634e-06 3.22344450347621e-05 NAMPT/PTGS2/CFLAR/MALAT1/PTEN/ZFP36L1/EGR1/EGLN1/CARD16/BNIP3L/HIF1A/NPEPPS/BACH1/CPEB4/NFE2L2 15 GO:0045069 regulation of viral genome replication 11/380 85/18722 1.15953726931656e-06 3.55843502576494e-05 IFITM2/CXCL8/IFITM1/APOBEC3A/IFI16/PLSCR1/DDX3X/ADAR/DDX5/N4BP1/IFITM3 11 GO:0051090 regulation of DNA-binding transcription factor activity 26/380 440/18722 1.24531119014964e-06 3.78746796874888e-05 S100A8/S100A12/S100A9/TMSB4X/SPI1/PELI1/TRIB1/HCK/NFAM1/PRKCB/IL1B/IRAK3/ARRB2/CFLAR/PTEN/CLEC7A/EGLN1/PYCARD/CARD16/HCLS1/STAT3/HSPA1A/PPP3CA/KDM5A/CAT/FLOT2 26 GO:0006968 cellular defense response 9/380 54/18722 1.26258507453877e-06 3.78746796874888e-05 MNDA/CXCR2/NCF1/C5AR1/TYROBP/NCF2/LSP1/LILRB2/LY96 9 GO:0042326 negative regulation of phosphorylation 24/380 385/18722 1.26766670877172e-06 3.78746796874888e-05 RGS2/PTPRC/SORL1/LRRK2/LYN/DUSP1/TRIB1/CDKN2D/RASSF2/MIDN/IL1B/IRAK3/PPP2R5A/ARRB2/MYADM/PTEN/PYCARD/STAT3/PRKAR1A/UBE2B/PTPN6/TAF7/ADAR/PAK2 24 GO:0002573 myeloid leukocyte differentiation 17/380 208/18722 1.26994203438569e-06 3.78746796874888e-05 EVI2B/LYN/LILRB3/TYROBP/JUNB/SPI1/TRIB1/FOS/RASSF2/CEBPB/SNX10/ZFP36L1/LBR/IFI16/HCLS1/TGFBR2/MYH9 17 GO:0050792 regulation of viral process 15/380 164/18722 1.31839042713888e-06 3.88466985252396e-05 IFITM2/CXCL8/IFITM1/ZFP36/APOBEC3A/CXCR4/FCN1/IFI16/PLSCR1/DDX3X/ADAR/DDX5/N4BP1/RAB7A/IFITM3 15 GO:0071706 tumor necrosis factor superfamily cytokine production 16/380 186/18722 1.33005225174964e-06 3.88466985252396e-05 PTPRC/LRRK2/TYROBP/ZFP36/TLR1/HLA-E/CYBA/IRAK3/ARRB2/TSPO/LY96/CLEC7A/PYCARD/STAT3/PTPN6/DICER1 16 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 16/380 186/18722 1.33005225174964e-06 3.88466985252396e-05 PTPRC/LRRK2/TYROBP/ZFP36/TLR1/HLA-E/CYBA/IRAK3/ARRB2/TSPO/LY96/CLEC7A/PYCARD/STAT3/PTPN6/DICER1 16 GO:1902905 positive regulation of supramolecular fiber organization 17/380 209/18722 1.35714471940976e-06 3.93664923746599e-05 GMFG/PLEK/CORO1A/HCK/WAS/GPR65/ACTR2/PYCARD/CDC42EP3/ARPC3/VASP/ARPC5/ACTR3/RICTOR/NIN/HSPA1A/PAK1 17 GO:0045637 regulation of myeloid cell differentiation 17/380 210/18722 1.44972503623406e-06 4.14836860030488e-05 EVI2B/LYN/LILRB3/TYROBP/B2M/ZFP36/SPI1/CSF3R/TRIB1/FOS/RASSF2/CEBPB/ZFP36L1/HCLS1/STAT3/HIF1A/HSPA1A 17 GO:0050866 negative regulation of cell activation 17/380 210/18722 1.44972503623406e-06 4.14836860030488e-05 MNDA/PTPRC/LST1/PGLYRP1/LYN/TYROBP/LAPTM5/BCL6/SPI1/PELI1/FGR/CEBPB/FGL2/LILRB2/IRF1/PRKAR1A/PTPN6 17 GO:0031348 negative regulation of defense response 19/380 258/18722 1.46920717892383e-06 4.14971743761096e-05 PTPRC/PGLYRP1/LYN/FPR2/HLA-B/ZFP36/HCK/HLA-E/FGR/ALOX5/SEC14L1/IRAK3/ARRB2/FGL2/HLA-A/TNFRSF1B/IFI16/USP15/ADAR 19 GO:0062207 regulation of pattern recognition receptor signaling pathway 12/380 105/18722 1.46979366149149e-06 4.14971743761096e-05 LYN/PELI1/TLR1/CYBA/SEC14L1/IRAK3/ARRB2/IRF1/USP15/PJA2/DDX3X/HSPA1A 12 GO:0022604 regulation of cell morphogenesis 21/380 309/18722 1.5150507192279e-06 4.2491654277683e-05 LST1/PLXNC1/RAC2/CORO1A/HCK/FMNL1/FGR/ARHGAP15/ITGB2/PREX1/MYADM/CXCR4/MSN/ACTR2/CDC42EP3/CD44/RHOG/CDC42SE1/MYH9/PHIP/DOCK5 21 GO:2000116 regulation of cysteine-type endopeptidase activity 18/380 235/18722 1.58589873944625e-06 4.41860602733872e-05 S100A8/S100A9/PTGS2/LAPTM5/PLAUR/CDKN2D/ARRB2/CFLAR/CLEC7A/PYCARD/TNFSF10/IFI16/CARD16/CD44/BID/DDX3X/PAK2/PSMB9 18 GO:0002886 regulation of myeloid leukocyte mediated immunity 9/380 56/18722 1.73549466110317e-06 4.80380384952412e-05 LYN/CD177/TYROBP/ADGRE2/RAC2/SPI1/HLA-E/FGR/ITGB2 9 GO:0050867 positive regulation of cell activation 25/380 420/18722 1.75608977221095e-06 4.82924687358011e-05 PTPRC/LRRK2/LYN/CD177/TYROBP/AIF1/BCL6/B2M/PELI1/PLEK/CORO1A/HLA-E/FGR/ITGB2/IL1B/HLA-A/LILRB2/CLEC7A/TNFSF13B/PYCARD/NFKBIZ/TGFBR2/CD55/PTPN6/FLOT2 25 GO:0033673 negative regulation of kinase activity 18/380 237/18722 1.79064902960794e-06 4.88675416436292e-05 RGS2/PTPRC/SORL1/LYN/DUSP1/TRIB1/CDKN2D/MIDN/IL1B/IRAK3/PPP2R5A/PTEN/PYCARD/PRKAR1A/PTPN6/TAF7/ADAR/PAK2 18 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 12/380 107/18722 1.80007945605812e-06 4.88675416436292e-05 PTPRC/HLA-B/B2M/SLC11A1/HLA-E/IL1B/HLA-A/CLEC7A/TNFSF13B/NFKBIZ/CD55/STX7 12 GO:0002832 negative regulation of response to biotic stimulus 12/380 108/18722 1.98858356255913e-06 5.3641091639732e-05 HLA-B/TRIB1/HLA-E/SEC14L1/IRAK3/ARRB2/FGL2/HLA-A/IFI16/CARD16/USP15/ADAR 12 GO:0032930 positive regulation of superoxide anion generation 6/380 20/18722 2.04772217024566e-06 5.4886730322724e-05 FPR2/CD177/TYROBP/ITGB2/CYBA/CLEC7A 6 GO:0050870 positive regulation of T cell activation 17/380 216/18722 2.13552026463803e-06 5.68800523317111e-05 PTPRC/LYN/AIF1/BCL6/B2M/CORO1A/HLA-E/IL1B/HLA-A/LILRB2/TNFSF13B/PYCARD/NFKBIZ/TGFBR2/CD55/PTPN6/FLOT2 17 GO:0002275 myeloid cell activation involved in immune response 11/380 91/18722 2.3072104927532e-06 6.10689777300614e-05 FCER1G/LYN/CD177/TYROBP/ADGRE2/RAC2/SPI1/FGR/ITGB2/PYCARD/STXBP3 11 GO:0042743 hydrogen peroxide metabolic process 9/380 58/18722 2.35375643488538e-06 6.19140279611155e-05 SOD2/RAC2/HBA2/CYBA/HBA1/HBB/HBG2/STAT3/CAT 9 GO:0002698 negative regulation of immune effector process 12/380 110/18722 2.41861477415575e-06 6.32273677070964e-05 PTPRC/PGLYRP1/HLA-B/BCL6/SPI1/HLA-E/IRAK3/ARRB2/FGL2/HLA-A/CD55/PTPN6 12 GO:2001236 regulation of extrinsic apoptotic signaling pathway 14/380 151/18722 2.52927060680507e-06 6.56382521136519e-05 G0S2/PTPRC/MCL1/IL1B/CFLAR/PTEN/STK4/PYCARD/TNFSF10/BID/DDX3X/HSPA1A/PAK2/PHIP 14 GO:0010038 response to metal ion 23/380 373/18722 2.54183550097731e-06 6.56382521136519e-05 S100A8/SOD2/PTGS2/LRRK2/NCF1/AQP9/ALOX5AP/JUNB/DUSP1/B2M/FOS/TXNIP/TSPO/PTEN/IQGAP1/PLSCR1/UBE2D3/CPNE3/HIF1A/PPP3CA/MAPK1/NFE2L2/CAT 23 GO:0051348 negative regulation of transferase activity 19/380 268/18722 2.58188433472712e-06 6.62683645913295e-05 RGS2/PTPRC/SORL1/LYN/DUSP1/ZFP36/TRIB1/CDKN2D/MIDN/IL1B/IRAK3/PPP2R5A/PTEN/PYCARD/PRKAR1A/PTPN6/TAF7/ADAR/PAK2 19 GO:0051092 positive regulation of NF-kappaB transcription factor activity 14/380 152/18722 2.73532594680257e-06 6.97837673777643e-05 S100A8/S100A12/S100A9/PRKCB/IL1B/IRAK3/CFLAR/CLEC7A/PYCARD/CARD16/STAT3/HSPA1A/CAT/FLOT2 14 GO:0035455 response to interferon-alpha 6/380 21/18722 2.81793093291819e-06 7.14607035982546e-05 IFITM2/IFITM1/MX2/ADAR/IFNAR1/IFITM3 6 GO:0052548 regulation of endopeptidase activity 25/380 432/18722 2.9028531439232e-06 7.267957799378e-05 S100A8/S100A9/PTGS2/SORL1/LYN/SERPINA1/LAPTM5/PLAUR/CDKN2D/MBP/ARRB2/CFLAR/CLEC7A/PYCARD/TNFSF10/IFI16/CARD16/PICALM/STAT3/CD44/BID/DDX3X/PAK2/PSMB9/NRDC 25 GO:0036293 response to decreased oxygen levels 21/380 322/18722 2.9127286889469e-06 7.267957799378e-05 NAMPT/SOD2/PTGS2/CYBA/CFLAR/MALAT1/PTEN/CXCR4/ZFP36L1/EGR1/EGLN1/CARD16/BNIP3L/TGFBR2/HIF1A/NPEPPS/BACH1/CPEB4/PAK1/NFE2L2/CAT 21 GO:0035456 response to interferon-beta 7/380 32/18722 2.91748010836897e-06 7.267957799378e-05 IFITM2/MNDA/IFITM1/IRF1/IFI16/PLSCR1/IFITM3 7 GO:0031663 lipopolysaccharide-mediated signaling pathway 9/380 60/18722 3.15284376548361e-06 7.80835868235269e-05 LYN/SPI1/TRIB1/HCK/IL1B/LY96/CARD16/CD55/MAPK1 9 GO:0071453 cellular response to oxygen levels 15/380 177/18722 3.42781839086379e-06 8.44000632866752e-05 NAMPT/PTGS2/CFLAR/MALAT1/PTEN/ZFP36L1/EGR1/EGLN1/CARD16/BNIP3L/HIF1A/NPEPPS/BACH1/CPEB4/NFE2L2 15 GO:0002705 positive regulation of leukocyte mediated immunity 13/380 134/18722 3.48752687326365e-06 8.53738514928992e-05 PTPRC/CD177/TYROBP/HLA-B/B2M/SPI1/HLA-E/ITGB2/IL1B/HLA-A/CLEC7A/CD55/STX7 13 GO:0002696 positive regulation of leukocyte activation 24/380 409/18722 3.62479189983352e-06 8.80583684495036e-05 PTPRC/LRRK2/LYN/CD177/TYROBP/AIF1/BCL6/B2M/PELI1/CORO1A/HLA-E/FGR/ITGB2/IL1B/HLA-A/LILRB2/CLEC7A/TNFSF13B/PYCARD/NFKBIZ/TGFBR2/CD55/PTPN6/FLOT2 24 GO:0002431 Fc receptor mediated stimulatory signaling pathway 7/380 33/18722 3.63877555576461e-06 8.80583684495036e-05 PTPRC/FCER1G/LYN/HCK/FGR/PLSCR1/PAK1 7 GO:0002718 regulation of cytokine production involved in immune response 11/380 96/18722 3.92736124797997e-06 9.4502130029518e-05 FFAR2/LAPTM5/BCL6/B2M/HLA-E/IL1B/IRAK3/HLA-A/CLEC7A/TNFRSF1B/CD55 11 GO:0048002 antigen processing and presentation of peptide antigen 9/380 62/18722 4.17472422551249e-06 9.9886763248844e-05 FCER1G/CTSS/HLA-B/HLA-C/B2M/SLC11A1/HLA-E/HLA-A/PYCARD 9 GO:0045646 regulation of erythrocyte differentiation 8/380 47/18722 4.2128106287522e-06 0.000100231758498683 LYN/B2M/ZFP36/SPI1/ZFP36L1/STAT3/HIF1A/HSPA1A 8 GO:0050671 positive regulation of lymphocyte proliferation 13/380 137/18722 4.46326199670391e-06 0.000105597288022576 PTPRC/AIF1/BCL6/PELI1/CORO1A/HLA-E/IL1B/HLA-A/LILRB2/TNFSF13B/PYCARD/TGFBR2/CD55 13 GO:0002704 negative regulation of leukocyte mediated immunity 9/380 63/18722 4.78429612524483e-06 0.000111941956300618 PTPRC/HLA-B/BCL6/SPI1/HLA-E/ARRB2/HLA-A/CD55/PTPN6 9 GO:0031343 positive regulation of cell killing 9/380 63/18722 4.78429612524483e-06 0.000111941956300618 PTPRC/TYROBP/HLA-B/B2M/SPI1/HLA-E/HLA-A/CLEC7A/STX7 9 GO:0032642 regulation of chemokine production 11/380 98/18722 4.81244006318056e-06 0.000111969854004766 FFAR2/AIF1/IL6R/MBP/IL1B/IL17RA/CLEC7A/EGR1/PYCARD/DDX3X/HIF1A 11 GO:0032946 positive regulation of mononuclear cell proliferation 13/380 138/18722 4.83836677281517e-06 0.000111969854004766 PTPRC/AIF1/BCL6/PELI1/CORO1A/HLA-E/IL1B/HLA-A/LILRB2/TNFSF13B/PYCARD/TGFBR2/CD55 13 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 8/380 48/18722 4.96671114544709e-06 0.00011431533533135 G0S2/PTPRC/PTEN/STK4/PYCARD/TNFSF10/BID/PAK2 8 GO:0045055 regulated exocytosis 17/380 230/18722 4.99688455133491e-06 0.000114388140945423 LRRK2/LYN/CD177/ADGRE2/RAC2/SPI1/PLEK/CORO1A/HCK/PRKCB/FGR/ITGB2/RAB27A/STX3/RAB11FIP1/STXBP3/MYH9 17 GO:0002444 myeloid leukocyte mediated immunity 11/380 99/18722 5.31693554951211e-06 0.000120412952150716 LYN/CD177/TYROBP/ADGRE2/TREM1/RAC2/SPI1/HLA-E/FGR/ITGB2/STXBP3 11 GO:0031341 regulation of cell killing 11/380 99/18722 5.31693554951211e-06 0.000120412952150716 PTPRC/TYROBP/HLA-B/B2M/SPI1/HLA-E/ARRB2/HLA-A/CLEC7A/CD55/STX7 11 GO:0030217 T cell differentiation 18/380 257/18722 5.61116285466008e-06 0.000126400397284497 PTPRC/FCER1G/BCL6/B2M/SPI1/IL6R/IL1B/PREX1/FGL2/LILRB2/ZFP36L1/EGR1/IRF1/NFKBIZ/ZFP36L2/SOS2/STAT3/TGFBR2 18 GO:0032102 negative regulation of response to external stimulus 24/380 420/18722 5.69392771357296e-06 0.000127586158026357 PTPRC/PGLYRP1/LYN/FPR2/HLA-B/AIF1/DUSP1/ZFP36/TRIB1/HCK/HLA-E/FGR/ALOX5/SEC14L1/IRAK3/ARRB2/FGL2/HLA-A/PTEN/TNFRSF1B/IFI16/CARD16/USP15/ADAR 24 GO:0050832 defense response to fungus 8/380 49/18722 5.83174403102218e-06 0.000129986505112521 S100A8/S100A12/S100A9/SPI1/CLEC4E/CLEC7A/COTL1/USP15 8 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 16/380 209/18722 6.06576945943209e-06 0.000134494940631911 S100A8/S100A9/PTGS2/LAPTM5/PLAUR/CDKN2D/ARRB2/CFLAR/CLEC7A/PYCARD/TNFSF10/CARD16/CD44/BID/DDX3X/PAK2 16 GO:0050921 positive regulation of chemotaxis 13/380 141/18722 6.13638120118153e-06 0.000135351949932311 CXCL8/CXCR2/C5AR1/FPR2/AIF1/TMSB4X/RAC2/GPSM3/SPI1/IL6R/CXCR4/STX3/MAPK1 13 GO:0042102 positive regulation of T cell proliferation 11/380 101/18722 6.4660648201413e-06 0.000141884893851287 PTPRC/AIF1/CORO1A/HLA-E/IL1B/HLA-A/LILRB2/TNFSF13B/PYCARD/TGFBR2/CD55 11 GO:0002224 toll-like receptor signaling pathway 12/380 121/18722 6.58920587495893e-06 0.000143120204067632 LYN/CTSS/PELI1/TLR1/CYBA/IRAK3/ARRB2/LY96/PIK3AP1/IRF1/PJA2/DDX3X 12 GO:0051091 positive regulation of DNA-binding transcription factor activity 18/380 260/18722 6.58995036438921e-06 0.000143120204067632 S100A8/S100A12/S100A9/NFAM1/PRKCB/IL1B/IRAK3/CFLAR/PTEN/CLEC7A/PYCARD/CARD16/HCLS1/STAT3/HSPA1A/PPP3CA/CAT/FLOT2 18 GO:0032928 regulation of superoxide anion generation 6/380 24/18722 6.63834387398326e-06 0.000143435644419996 FPR2/CD177/TYROBP/ITGB2/CYBA/CLEC7A 6 GO:0090322 regulation of superoxide metabolic process 7/380 36/18722 6.74710138336978e-06 0.00014504555511965 FPR2/CD177/TYROBP/ITGB2/CYBA/CLEC7A/NFE2L2 7 GO:0006605 protein targeting 20/380 314/18722 7.1393926324301e-06 0.000152703675749199 SORL1/LRRK2/NCF1/RAC2/LAPTM5/ITGB2/ZDHHC18/TSPO/SDCBP/RAB27A/BNIP3L/UBE2D3/BID/YWHAZ/RAB8B/NPEPPS/SH3GLB1/PAK1/NCOA4/RAB7A 20 GO:0002688 regulation of leukocyte chemotaxis 12/380 122/18722 7.17646117175174e-06 0.000152725191268184 CXCL8/CXCR2/C5AR1/LYN/FPR2/AIF1/RAC2/GPSM3/DUSP1/SPI1/IL6R/MAPK1 12 GO:0006469 negative regulation of protein kinase activity 16/380 212/18722 7.27258174167872e-06 0.000153996918380047 RGS2/PTPRC/SORL1/LYN/DUSP1/TRIB1/CDKN2D/IL1B/IRAK3/PTEN/PYCARD/PRKAR1A/PTPN6/TAF7/ADAR/PAK2 16 GO:0001933 negative regulation of protein phosphorylation 21/380 342/18722 7.42220482451212e-06 0.000156383270805019 RGS2/PTPRC/SORL1/LRRK2/LYN/DUSP1/TRIB1/CDKN2D/RASSF2/IL1B/IRAK3/ARRB2/MYADM/PTEN/PYCARD/PRKAR1A/UBE2B/PTPN6/TAF7/ADAR/PAK2 21 GO:0002709 regulation of T cell mediated immunity 10/380 85/18722 8.52339582378089e-06 0.00017651182514777 PTPRC/HLA-B/B2M/HLA-E/WAS/IL1B/HLA-A/TNFRSF1B/CD55/STX7 10 GO:0055072 iron ion homeostasis 10/380 85/18722 8.52339582378089e-06 0.00017651182514777 STEAP4/SLC25A37/FTH1/B2M/SLC11A1/FTL/FBXL5/PICALM/HIF1A/NCOA4 10 GO:0051607 defense response to virus 18/380 265/18722 8.56658178141464e-06 0.00017651182514777 IFITM2/PTPRC/IFITM1/MX2/LYST/ITGAX/APOBEC3A/SEC14L1/FGL2/PYCARD/IRF1/IFI16/BNIP3L/USP15/PLSCR1/IFNGR2/ADAR/IFITM3 18 GO:0140546 defense response to symbiont 18/380 265/18722 8.56658178141464e-06 0.00017651182514777 IFITM2/PTPRC/IFITM1/MX2/LYST/ITGAX/APOBEC3A/SEC14L1/FGL2/PYCARD/IRF1/IFI16/BNIP3L/USP15/PLSCR1/IFNGR2/ADAR/IFITM3 18 GO:0098581 detection of external biotic stimulus 6/380 25/18722 8.58593529644407e-06 0.00017651182514777 PGLYRP1/HLA-B/TLR1/HLA-A/LY96/CLEC7A 6 GO:0052547 regulation of peptidase activity 25/380 461/18722 9.00830371263131e-06 0.000184300319917843 S100A8/S100A9/PTGS2/SORL1/LYN/SERPINA1/LAPTM5/PLAUR/CDKN2D/MBP/ARRB2/CFLAR/CLEC7A/PYCARD/TNFSF10/IFI16/CARD16/PICALM/STAT3/CD44/BID/DDX3X/PAK2/PSMB9/NRDC 25 GO:0070482 response to oxygen levels 21/380 347/18722 9.26316498554258e-06 0.000188603383239292 NAMPT/SOD2/PTGS2/CYBA/CFLAR/MALAT1/PTEN/CXCR4/ZFP36L1/EGR1/EGLN1/CARD16/BNIP3L/TGFBR2/HIF1A/NPEPPS/BACH1/CPEB4/PAK1/NFE2L2/CAT 21 GO:0071496 cellular response to external stimulus 20/380 320/18722 9.4421442003976e-06 0.00019132765879753 NAMPT/PTGS2/PTPRC/LRRK2/LYN/AIF1/FOS/CNN2/CYBA/IL1B/GLUL/IRF1/IFI16/MAP3K2/RALB/NCOA1/CPEB4/SH3GLB1/MAPK1/NFE2L2 20 GO:0002285 lymphocyte activation involved in immune response 15/380 194/18722 1.04923553709645e-05 0.00021159583331445 PTPRC/LCP1/PGLYRP1/FCER1G/BCL6/SLC11A1/SPI1/CORO1A/IL6R/FGL2/APBB1IP/RAB27A/NFKBIZ/STAT3/NBN 15 GO:0002707 negative regulation of lymphocyte mediated immunity 8/380 53/18722 1.06787500588891e-05 0.000214334154025571 PTPRC/HLA-B/BCL6/HLA-E/ARRB2/HLA-A/CD55/PTPN6 8 GO:0033674 positive regulation of kinase activity 25/380 467/18722 1.12341034845075e-05 0.000224417114419289 S100A12/PTPRC/LRRK2/NCF1/ACSL1/LYN/FPR2/SLC11A1/IL6R/RASSF2/FGR/IL1B/IQGAP1/STK4/EGR1/OSBPL8/LCP2/DAZAP2/RALB/TGFBR2/RICTOR/DDX3X/PAK2/PAK1/NBN 25 GO:0010720 positive regulation of cell development 19/380 298/18722 1.19171819376914e-05 0.00023694490847945 LYN/TYROBP/PLXNC1/TRIB1/IL1B/PREX1/MYADM/TSPO/CXCR4/CLEC7A/TNFRSF1B/ACTR2/NUMB/NIN/HIF1A/DICER1/MME/PAK1/DOCK5 19 GO:0071456 cellular response to hypoxia 13/380 151/18722 1.29561199776316e-05 0.000256397981800326 PTGS2/CFLAR/MALAT1/PTEN/ZFP36L1/EGR1/EGLN1/CARD16/BNIP3L/HIF1A/NPEPPS/BACH1/NFE2L2 13 GO:0002456 T cell mediated immunity 11/380 109/18722 1.35083814226062e-05 0.000266083699184824 PTPRC/HLA-B/B2M/HLA-E/WAS/IL1B/HLA-A/RAB27A/TNFRSF1B/CD55/STX7 11 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 21/380 356/18722 1.36443060536498e-05 0.000267516833968551 PTPRC/FCER1G/HLA-B/BCL6/B2M/SLC11A1/IL6R/HLA-E/WAS/IL1B/HLA-A/RAB27A/CLEC7A/TNFRSF1B/TNFSF13B/NFKBIZ/STAT3/CD55/PTPN6/STX7/NBN 21 GO:0043434 response to peptide hormone 23/380 414/18722 1.40466699728254e-05 0.000274136623663206 PTGS2/SORL1/LYN/PRKCB/CYBA/IL1B/PTPRE/CFLAR/BTG2/PTEN/IQGAP1/ZFP36L1/EGR1/OSBPL8/TNFSF10/STAT3/BTG1/RAB8B/STXBP3/PHIP/PAK1/NFE2L2/CAT 23 GO:0019079 viral genome replication 12/380 131/18722 1.48959046458679e-05 0.000289376863189224 IFITM2/CXCL8/IFITM1/APOBEC3A/ATG16L2/IFI16/PLSCR1/DDX3X/ADAR/DDX5/N4BP1/IFITM3 12 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 8/380 56/18722 1.6231150003735e-05 0.000312449637571899 PTPRC/TYROBP/HLA-B/B2M/SPI1/HLA-E/HLA-A/STX7 8 GO:0002711 positive regulation of T cell mediated immunity 8/380 56/18722 1.6231150003735e-05 0.000312449637571899 PTPRC/HLA-B/B2M/HLA-E/IL1B/HLA-A/CD55/STX7 8 GO:0070997 neuron death 21/380 361/18722 1.68153951000137e-05 0.000322231666283069 NAMPT/SOD2/SORL1/LRRK2/C5AR1/TYROBP/CORO1A/FOS/MCL1/ITGB2/CEBPB/ARRB2/BTG2/TNFRSF1B/EGR1/PICALM/STAT3/BID/NQO2/HIF1A/CPEB4 21 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 5/380 17/18722 1.69798965197523e-05 0.000322690148839451 HLA-B/HLA-C/B2M/HLA-E/HLA-A 5 GO:0017157 regulation of exocytosis 15/380 202/18722 1.69917126779687e-05 0.000322690148839451 LRRK2/LYN/CD177/ADGRE2/RAC2/SPI1/PRKCB/FGR/ITGB2/SDCBP/RAB27A/RAB8B/STXBP3/VPS4B/RAB7A 15 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 6/380 28/18722 1.7348048191633e-05 0.000323651912297646 FCER1G/HLA-B/HLA-C/B2M/HLA-E/HLA-A 6 GO:0002507 tolerance induction 6/380 28/18722 1.7348048191633e-05 0.000323651912297646 LYN/HLA-B/HLA-E/IRAK3/LILRB2/TGFBR2 6 GO:0002675 positive regulation of acute inflammatory response 6/380 28/18722 1.7348048191633e-05 0.000323651912297646 PTGS2/FFAR2/OSM/ALOX5AP/HLA-E/IL1B 6 GO:0038094 Fc-gamma receptor signaling pathway 6/380 28/18722 1.7348048191633e-05 0.000323651912297646 PTPRC/FCER1G/LYN/HCK/FGR/PAK1 6 GO:0009743 response to carbohydrate 17/380 253/18722 1.74991686332229e-05 0.000325039382288154 NAMPT/SOD2/PTGS2/LYN/TXNIP/PRKCB/CYBA/PTEN/CLEC7A/ZFP36L1/GLUL/EGR1/TGFBR2/NADK/HIF1A/PPP3CA/CAT 17 GO:0001666 response to hypoxia 19/380 307/18722 1.80802948802083e-05 0.000333663839424503 SOD2/PTGS2/CYBA/CFLAR/MALAT1/PTEN/CXCR4/ZFP36L1/EGR1/EGLN1/CARD16/BNIP3L/TGFBR2/HIF1A/NPEPPS/BACH1/PAK1/NFE2L2/CAT 19 GO:0010950 positive regulation of endopeptidase activity 14/380 179/18722 1.81210585755929e-05 0.000333663839424503 S100A8/S100A9/LYN/LAPTM5/MBP/CFLAR/CLEC7A/PYCARD/TNFSF10/IFI16/PICALM/STAT3/BID/DDX3X 14 GO:0034121 regulation of toll-like receptor signaling pathway 9/380 75/18722 2.04956648236506e-05 0.000373196544034645 LYN/PELI1/TLR1/CYBA/IRAK3/ARRB2/IRF1/PJA2/DDX3X 9 GO:0045766 positive regulation of angiogenesis 14/380 181/18722 2.05324190696747e-05 0.000373196544034645 CXCL8/CXCR2/C5AR1/LRG1/ITGAX/PRKCB/IL1B/CXCR4/JAK1/STAT3/TGFBR2/BTG1/HIF1A/NFE2L2 14 GO:1904018 positive regulation of vasculature development 14/380 181/18722 2.05324190696747e-05 0.000373196544034645 CXCL8/CXCR2/C5AR1/LRG1/ITGAX/PRKCB/IL1B/CXCR4/JAK1/STAT3/TGFBR2/BTG1/HIF1A/NFE2L2 14 GO:0002690 positive regulation of leukocyte chemotaxis 10/380 94/18722 2.09507840735763e-05 0.000379173378425622 CXCL8/CXCR2/C5AR1/FPR2/AIF1/RAC2/GPSM3/SPI1/IL6R/MAPK1 10 GO:0001916 positive regulation of T cell mediated cytotoxicity 6/380 29/18722 2.15016892834506e-05 0.000387487889852822 PTPRC/HLA-B/B2M/HLA-E/HLA-A/STX7 6 GO:0002532 production of molecular mediator involved in inflammatory response 10/380 95/18722 2.29990114487406e-05 0.000407975325933935 NCF1/LYN/ALOX5AP/GPSM3/ALOX5/IL17RA/CLEC7A/PYCARD/STAT3/HIF1A 10 GO:0002223 stimulatory C-type lectin receptor signaling pathway 5/380 18/18722 2.31202073728794e-05 0.000407975325933935 LYN/TYROBP/CLEC7A/PAK2/PAK1 5 GO:0034134 toll-like receptor 2 signaling pathway 5/380 18/18722 2.31202073728794e-05 0.000407975325933935 LYN/TLR1/CYBA/PIK3AP1/PJA2 5 GO:1990840 response to lectin 5/380 18/18722 2.31202073728794e-05 0.000407975325933935 LYN/TYROBP/CLEC7A/PAK2/PAK1 5 GO:1990858 cellular response to lectin 5/380 18/18722 2.31202073728794e-05 0.000407975325933935 LYN/TYROBP/CLEC7A/PAK2/PAK1 5 GO:0055076 transition metal ion homeostasis 12/380 138/18722 2.51755206609656e-05 0.000442399709540204 S100A8/S100A9/STEAP4/SLC25A37/FTH1/B2M/SLC11A1/FTL/FBXL5/PICALM/HIF1A/NCOA4 12 GO:0002685 regulation of leukocyte migration 15/380 210/18722 2.68313852586581e-05 0.000469467870580164 CXCL8/CXCR2/C5AR1/LYN/FPR2/AIF1/RAC2/GPSM3/DUSP1/SPI1/IL6R/MSN/PYCARD/RHOG/MAPK1 15 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 7/380 44/18722 2.69375897404911e-05 0.000469467870580164 PELI1/TLR1/CYBA/USP15/PJA2/DDX3X/HSPA1A 7 GO:0009620 response to fungus 8/380 60/18722 2.72425317833484e-05 0.000472836565993772 S100A8/S100A12/S100A9/SPI1/CLEC4E/CLEC7A/COTL1/USP15 8 GO:0071346 cellular response to interferon-gamma 11/380 118/18722 2.86322440297244e-05 0.000494928789656664 AIF1/HCK/WAS/VIM/ACTR2/IRF1/JAK1/ZYX/IFNGR2/ACTR3/STXBP3 11 GO:1901214 regulation of neuron death 19/380 319/18722 3.06877526473393e-05 0.000524810226660114 SOD2/SORL1/LRRK2/C5AR1/TYROBP/CORO1A/FOS/MCL1/ITGB2/CEBPB/ARRB2/BTG2/TNFRSF1B/EGR1/PICALM/STAT3/NQO2/HIF1A/CPEB4 19 GO:0034113 heterotypic cell-cell adhesion 8/380 61/18722 3.08062291269302e-05 0.000524810226660114 PTPRC/ITGAX/MBP/ITGB2/IL1B/MYADM/LILRB2/CD44 8 GO:0002483 antigen processing and presentation of endogenous peptide antigen 5/380 19/18722 3.08566107292487e-05 0.000524810226660114 HLA-B/HLA-C/B2M/HLA-E/HLA-A 5 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 5/380 19/18722 3.08566107292487e-05 0.000524810226660114 CD177/TYROBP/SPI1/HLA-E/ITGB2 5 GO:0071901 negative regulation of protein serine/threonine kinase activity 11/380 120/18722 3.35010949502068e-05 0.000567508548456503 RGS2/SORL1/LYN/DUSP1/CDKN2D/IL1B/IRAK3/PTEN/PYCARD/PRKAR1A/PTPN6 11 GO:0032757 positive regulation of interleukin-8 production 8/380 62/18722 3.47516372604735e-05 0.000586347345809184 FFAR2/TLR1/IL1B/CLEC7A/FCN1/PYCARD/STAT3/HSPA1A 8 GO:0043300 regulation of leukocyte degranulation 7/380 46/18722 3.63366875308729e-05 0.000610658221004948 LYN/CD177/ADGRE2/RAC2/SPI1/FGR/ITGB2 7 GO:0007596 blood coagulation 15/380 217/18722 3.92582897492316e-05 0.000654680948176112 FCER1G/LYN/SERPINA1/PLEK/ACTB/PLAUR/WAS/RAB27A/HBB/JMJD1C/PLSCR1/PTPN6/STXBP3/MYH9/NFE2L2 15 GO:0098869 cellular oxidant detoxification 10/380 101/18722 3.92653980724279e-05 0.000654680948176112 S100A9/SOD2/PTGS2/ALOX5AP/HBA2/HBA1/HBB/HBG2/NFE2L2/CAT 10 GO:0002706 regulation of lymphocyte mediated immunity 13/380 168/18722 4.02090998227809e-05 0.000666717097746411 PTPRC/HLA-B/BCL6/B2M/HLA-E/WAS/IL1B/ARRB2/HLA-A/TNFRSF1B/CD55/PTPN6/STX7 13 GO:0002577 regulation of antigen processing and presentation 5/380 20/18722 4.04595735822497e-05 0.000666717097746411 SLC11A1/WAS/FGL2/LILRB2/PYCARD 5 GO:0098543 detection of other organism 5/380 20/18722 4.04595735822497e-05 0.000666717097746411 PGLYRP1/HLA-B/TLR1/HLA-A/CLEC7A 5 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 7/380 47/18722 4.1958365988744e-05 0.000688735193652446 KLF2/CEBPB/EGR1/HIF1A/HSPA1A/BACH1/NFE2L2 7 GO:0001910 regulation of leukocyte mediated cytotoxicity 9/380 82/18722 4.22170399959967e-05 0.000690305653988595 PTPRC/TYROBP/HLA-B/B2M/SPI1/HLA-E/ARRB2/HLA-A/STX7 9 GO:0032677 regulation of interleukin-8 production 10/380 102/18722 4.27597034218552e-05 0.000696489784582911 PTPRC/FFAR2/TMSB4X/TLR1/IL1B/CLEC7A/FCN1/PYCARD/STAT3/HSPA1A 10 GO:0045860 positive regulation of protein kinase activity 21/380 386/18722 4.49538954601899e-05 0.000729424319057104 S100A12/PTPRC/LRRK2/NCF1/ACSL1/SLC11A1/IL6R/RASSF2/IL1B/IQGAP1/STK4/EGR1/OSBPL8/LCP2/DAZAP2/RALB/TGFBR2/RICTOR/DDX3X/PAK2/PAK1 21 GO:0032637 interleukin-8 production 10/380 103/18722 4.65160120551657e-05 0.000746198375607919 PTPRC/FFAR2/TMSB4X/TLR1/IL1B/CLEC7A/FCN1/PYCARD/STAT3/HSPA1A 10 GO:0032760 positive regulation of tumor necrosis factor production 10/380 103/18722 4.65160120551657e-05 0.000746198375607919 PTPRC/LRRK2/TYROBP/TLR1/HLA-E/CYBA/LY96/CLEC7A/PYCARD/STAT3 10 GO:0050672 negative regulation of lymphocyte proliferation 9/380 83/18722 4.65162623755586e-05 0.000746198375607919 MNDA/LST1/LYN/TYROBP/PELI1/CEBPB/LILRB2/PRKAR1A/PTPN6 9 GO:0002720 positive regulation of cytokine production involved in immune response 8/380 65/18722 4.92051070563642e-05 0.000784000643640951 FFAR2/LAPTM5/B2M/HLA-E/IL1B/HLA-A/CLEC7A/CD55 8 GO:0043312 neutrophil degranulation 4/380 11/18722 4.92430156336465e-05 0.000784000643640951 CD177/SPI1/ITGB2/STXBP3 4 GO:1903900 regulation of viral life cycle 12/380 148/18722 5.03129722530617e-05 0.000795473268364496 IFITM2/CXCL8/IFITM1/APOBEC3A/FCN1/IFI16/PLSCR1/DDX3X/ADAR/DDX5/N4BP1/IFITM3 12 GO:0033002 muscle cell proliferation 16/380 248/18722 5.03392764868205e-05 0.000795473268364496 NAMPT/SOD2/PTGS2/AIF1/TRIB1/IL6R/CYBA/CFLAR/PTEN/STAT3/PRKAR1A/TGFBR2/NQO2/SF1/PAK1/MAPK1 16 GO:0000302 response to reactive oxygen species 15/380 222/18722 5.09967854796794e-05 0.000796855213419234 SOD2/LRRK2/NCF1/DUSP1/FOS/KLF2/TXNIP/HBA2/KDM6B/HBA1/HBB/HIF1A/MAPK1/NFE2L2/CAT 15 GO:0007599 hemostasis 15/380 222/18722 5.09967854796794e-05 0.000796855213419234 FCER1G/LYN/SERPINA1/PLEK/ACTB/PLAUR/WAS/RAB27A/HBB/JMJD1C/PLSCR1/PTPN6/STXBP3/MYH9/NFE2L2 15 GO:0050817 coagulation 15/380 222/18722 5.09967854796794e-05 0.000796855213419234 FCER1G/LYN/SERPINA1/PLEK/ACTB/PLAUR/WAS/RAB27A/HBB/JMJD1C/PLSCR1/PTPN6/STXBP3/MYH9/NFE2L2 15 GO:0032945 negative regulation of mononuclear cell proliferation 9/380 84/18722 5.11793667178351e-05 0.000796855213419234 MNDA/LST1/LYN/TYROBP/PELI1/CEBPB/LILRB2/PRKAR1A/PTPN6 9 GO:0046641 positive regulation of alpha-beta T cell proliferation 5/380 21/18722 5.22225869101659e-05 0.000809700850057884 PTPRC/HLA-E/HLA-A/TGFBR2/CD55 5 GO:0010952 positive regulation of peptidase activity 14/380 197/18722 5.23867846318442e-05 0.000809700850057884 S100A8/S100A9/LYN/LAPTM5/MBP/CFLAR/CLEC7A/PYCARD/TNFSF10/IFI16/PICALM/STAT3/BID/DDX3X 14 GO:2001235 positive regulation of apoptotic signaling pathway 11/380 126/18722 5.26256440444293e-05 0.000810434918284211 S100A8/G0S2/S100A9/PTPRC/MCL1/PTEN/STK4/PYCARD/TNFSF10/BID/PAK2 11 GO:0050920 regulation of chemotaxis 15/380 223/18722 5.36831562236498e-05 0.000823725241330279 CXCL8/CXCR2/C5AR1/LYN/FPR2/AIF1/TMSB4X/RAC2/GPSM3/DUSP1/SPI1/IL6R/CXCR4/STX3/MAPK1 15 GO:0051251 positive regulation of lymphocyte activation 20/380 362/18722 5.50314782564065e-05 0.000840134838843276 PTPRC/LYN/TYROBP/AIF1/BCL6/B2M/PELI1/CORO1A/HLA-E/IL1B/HLA-A/LILRB2/CLEC7A/TNFSF13B/PYCARD/NFKBIZ/TGFBR2/CD55/PTPN6/FLOT2 20 GO:0001913 T cell mediated cytotoxicity 7/380 49/18722 5.53477261008912e-05 0.000840134838843276 PTPRC/HLA-B/B2M/HLA-E/HLA-A/RAB27A/STX7 7 GO:0006953 acute-phase response 7/380 49/18722 5.53477261008912e-05 0.000840134838843276 PTGS2/SERPINA1/IL6R/CEBPB/IL1B/PLSCR1/STAT3 7 GO:0045619 regulation of lymphocyte differentiation 13/380 174/18722 5.78570780390381e-05 0.000875088305340451 PTPRC/PGLYRP1/BCL6/NFAM1/FGL2/LILRB2/ZFP36L1/IRF1/NFKBIZ/ZFP36L2/SOS2/TGFBR2/PTPN6 13 GO:0022406 membrane docking 9/380 86/18722 6.16959107715502e-05 0.000926532560700408 PLEK/MSN/VMP1/STX3/RALB/RAB8B/STX7/STXBP3/RAB7A 9 GO:2000117 negative regulation of cysteine-type endopeptidase activity 9/380 86/18722 6.16959107715502e-05 0.000926532560700408 PTGS2/PLAUR/CDKN2D/ARRB2/IFI16/CARD16/CD44/DDX3X/PAK2 9 GO:0060337 type I interferon signaling pathway 7/380 50/18722 6.32474511150581e-05 0.000946476874460321 IFITM2/IFITM1/JAK1/PTPN6/ADAR/IFNAR1/IFITM3 7 GO:0034612 response to tumor necrosis factor 16/380 253/18722 6.38443787246196e-05 0.000952045577108323 CXCL8/PTGS2/TMSB4X/LAPTM5/ZFP36/KLF2/CYBA/TNFRSF1B/ZFP36L1/TNFSF13B/PYCARD/CARD16/ZFP36L2/HSPA1A/MAPK1/NFE2L2 16 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 10/380 107/18722 6.44890920882737e-05 0.000958285280680137 PTPRC/LRRK2/TYROBP/TLR1/HLA-E/CYBA/LY96/CLEC7A/PYCARD/STAT3 10 GO:0046640 regulation of alpha-beta T cell proliferation 6/380 35/18722 6.62961030246881e-05 0.000981692294788651 PTPRC/HLA-E/HLA-A/IRF1/TGFBR2/CD55 6 GO:0042267 natural killer cell mediated cytotoxicity 8/380 68/18722 6.83515901204808e-05 0.00100860273226563 HLA-B/CORO1A/LYST/HLA-E/ARRB2/HLA-A/RAB27A/PTPN6 8 GO:0033157 regulation of intracellular protein transport 15/380 229/18722 7.25654087512694e-05 0.00106337199329282 PTGS2/SORL1/LRRK2/LCP1/RAC2/ITGB2/IL1B/BNIP3L/HCLS1/UBE2D3/OAZ1/NPEPPS/SH3GLB1/PAK1/MAPK1 15 GO:0071356 cellular response to tumor necrosis factor 15/380 229/18722 7.25654087512694e-05 0.00106337199329282 CXCL8/TMSB4X/LAPTM5/ZFP36/KLF2/CYBA/TNFRSF1B/ZFP36L1/TNFSF13B/PYCARD/CARD16/ZFP36L2/HSPA1A/MAPK1/NFE2L2 15 GO:0009896 positive regulation of catabolic process 24/380 492/18722 7.395463389143e-05 0.00107999267079381 SORL1/LRRK2/LAPTM5/ZFP36/TRIB1/IL1B/BTG2/PTEN/AGTPBP1/TNFRSF1B/FBXL5/MSN/ZFP36L1/RALB/ZFP36L2/BNIP3L/BID/OAZ1/HIF1A/HSPA1A/SH3GLB1/NRDC/NFE2L2/RAB7A 24 GO:0045732 positive regulation of protein catabolic process 15/380 231/18722 8.00373875596216e-05 0.00116480527943298 SORL1/LRRK2/LAPTM5/TRIB1/IL1B/PTEN/AGTPBP1/TNFRSF1B/FBXL5/MSN/OAZ1/HSPA1A/NRDC/NFE2L2/RAB7A 15 GO:0045010 actin nucleation 7/380 52/18722 8.18165452302526e-05 0.00118257020153625 GMFG/CORO1A/WAS/ACTR2/ARPC3/ARPC5/ACTR3 7 GO:0071357 cellular response to type I interferon 7/380 52/18722 8.18165452302526e-05 0.00118257020153625 IFITM2/IFITM1/JAK1/PTPN6/ADAR/IFNAR1/IFITM3 7 GO:0034109 homotypic cell-cell adhesion 9/380 90/18722 8.82486681179809e-05 0.00126689189654118 LYN/PLEK/ACTB/PLAUR/HBB/JAK1/PTPN6/STXBP3/MYH9 9 GO:0070664 negative regulation of leukocyte proliferation 9/380 90/18722 8.82486681179809e-05 0.00126689189654118 MNDA/LST1/LYN/TYROBP/PELI1/CEBPB/LILRB2/PRKAR1A/PTPN6 9 GO:0019058 viral life cycle 18/380 317/18722 9.13031753067179e-05 0.0013063140115674 IFITM2/CXCL8/IFITM1/APOBEC3A/ATG16L2/CXCR4/FCN1/IFI16/PLSCR1/CD55/DDX3X/ADAR/DDX5/HSPA1A/VPS4B/N4BP1/RAB7A/IFITM3 18 GO:0043620 regulation of DNA-templated transcription in response to stress 7/380 53/18722 9.26418618867647e-05 0.00132100432690387 KLF2/CEBPB/EGR1/HIF1A/HSPA1A/BACH1/NFE2L2 7 GO:0002228 natural killer cell mediated immunity 8/380 71/18722 9.33146205678813e-05 0.00132169705051832 HLA-B/CORO1A/LYST/HLA-E/ARRB2/HLA-A/RAB27A/PTPN6 8 GO:0045824 negative regulation of innate immune response 8/380 71/18722 9.33146205678813e-05 0.00132169705051832 HLA-B/HLA-E/IRAK3/ARRB2/HLA-A/IFI16/USP15/ADAR 8 GO:0002687 positive regulation of leukocyte migration 11/380 135/18722 9.85649991657538e-05 0.00139140923822322 CXCL8/CXCR2/C5AR1/FPR2/AIF1/RAC2/GPSM3/SPI1/IL6R/PYCARD/MAPK1 11 GO:0034135 regulation of toll-like receptor 2 signaling pathway 4/380 13/18722 0.000103307923116591 0.0014487054781416 LYN/TLR1/CYBA/PJA2 4 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 4/380 13/18722 0.000103307923116591 0.0014487054781416 EGR1/HIF1A/BACH1/NFE2L2 4 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 5/380 24/18722 0.000103747848986443 0.00145007307081712 PTPRC/HLA-B/HLA-E/ARRB2/HLA-A 5 GO:0048525 negative regulation of viral process 9/380 92/18722 0.000104763777159458 0.00145768307165084 IFITM2/IFITM1/ZFP36/APOBEC3A/FCN1/IFI16/PLSCR1/N4BP1/IFITM3 9 GO:0032868 response to insulin 16/380 264/18722 0.000105254555866163 0.00145768307165084 SORL1/LYN/PRKCB/IL1B/PTPRE/CFLAR/PTEN/ZFP36L1/EGR1/OSBPL8/TNFSF10/RAB8B/STXBP3/PHIP/PAK1/CAT 16 GO:1903305 regulation of regulated secretory pathway 11/380 136/18722 0.000105324916157062 0.00145768307165084 LRRK2/LYN/CD177/ADGRE2/RAC2/SPI1/PRKCB/FGR/ITGB2/RAB27A/STXBP3 11 GO:0090316 positive regulation of intracellular protein transport 12/380 160/18722 0.000106884217331337 0.00147287035945724 PTGS2/SORL1/RAC2/ITGB2/IL1B/HCLS1/UBE2D3/OAZ1/NPEPPS/SH3GLB1/PAK1/MAPK1 12 GO:0046633 alpha-beta T cell proliferation 6/380 38/18722 0.000107117844324163 0.00147287035945724 PTPRC/HLA-E/HLA-A/IRF1/TGFBR2/CD55 6 GO:0002286 T cell activation involved in immune response 10/380 114/18722 0.000110195010641793 0.0015054060324774 LCP1/FCER1G/BCL6/SLC11A1/IL6R/FGL2/APBB1IP/RAB27A/NFKBIZ/STAT3 10 GO:0007041 lysosomal transport 10/380 114/18722 0.000110195010641793 0.0015054060324774 SORL1/LRRK2/LAPTM5/LYST/DENND3/IGF2R/HSPA1A/VPS4B/NCOA4/RAB7A 10 GO:0038066 p38MAPK cascade 7/380 55/18722 0.000117795117387154 0.00160405891361606 NCF1/DUSP1/ZFP36/SPI1/IL1B/ZFP36L1/PJA2 7 GO:0001914 regulation of T cell mediated cytotoxicity 6/380 39/18722 0.00012444884228489 0.00168383657212942 PTPRC/HLA-B/B2M/HLA-E/HLA-A/STX7 6 GO:0034314 Arp2/3 complex-mediated actin nucleation 6/380 39/18722 0.00012444884228489 0.00168383657212942 GMFG/WAS/ACTR2/ARPC3/ARPC5/ACTR3 6 GO:1990748 cellular detoxification 10/380 116/18722 0.00012743239997156 0.00171871405694126 S100A9/SOD2/PTGS2/ALOX5AP/HBA2/HBA1/HBB/HBG2/NFE2L2/CAT 10 GO:0045071 negative regulation of viral genome replication 7/380 56/18722 0.000132304255584785 0.00177875721397323 IFITM2/IFITM1/APOBEC3A/IFI16/PLSCR1/N4BP1/IFITM3 7 GO:1903320 regulation of protein modification by small protein conjugation or removal 15/380 242/18722 0.000134393429004443 0.00180112712605638 LRRK2/LAPTM5/PELI1/IVNS1ABP/RASSF5/ARRB2/TSPO/PTEN/EGR1/UBE2D1/DDX3X/HIF1A/HSPA1A/CUL3/N4BP1 15 GO:0002700 regulation of production of molecular mediator of immune response 12/380 164/18722 0.000135133615512633 0.00180533394856783 PTPRC/FFAR2/LAPTM5/BCL6/B2M/HLA-E/IL1B/IRAK3/HLA-A/CLEC7A/TNFRSF1B/CD55 12 GO:0045429 positive regulation of nitric oxide biosynthetic process 6/380 40/18722 0.000143930561156174 0.00191681108961131 PTGS2/AIF1/KLF2/IL1B/CLEC7A/HBB 6 GO:0006898 receptor-mediated endocytosis 15/380 244/18722 0.000147141218150251 0.0019511887461159 CXCL8/CXCR2/SORL1/FCER1G/FPR2/CXCR1/B2M/ITGB2/ARRB2/SDCBP/CAP1/IGF2R/NUMB/PICALM/TGFBR2 15 GO:1901653 cellular response to peptide 19/380 359/18722 0.000147433388136267 0.0019511887461159 NAMPT/SORL1/LYN/FPR2/KLF2/PRKCB/VIM/CYBA/IL1B/PTPRE/CFLAR/PTEN/ZFP36L1/OSBPL8/STAT3/RAB8B/PHIP/PAK1/NFE2L2 19 GO:0043112 receptor metabolic process 12/380 166/18722 0.00015150831875319 0.00199887143277184 CXCL8/CXCR2/SORL1/FCER1G/CXCR1/LAPTM5/ITGB2/ARRB2/SDCBP/NUMB/PICALM/SH3GLB1 12 GO:0019883 antigen processing and presentation of endogenous antigen 5/380 26/18722 0.000155292279892856 0.00203610775648992 HLA-B/HLA-C/B2M/HLA-E/HLA-A 5 GO:1900017 positive regulation of cytokine production involved in inflammatory response 5/380 26/18722 0.000155292279892856 0.00203610775648992 GPSM3/IL17RA/CLEC7A/STAT3/HIF1A 5 GO:0014909 smooth muscle cell migration 9/380 97/18722 0.000157699360259005 0.00205674194410081 SORL1/AIF1/TRIB1/IQGAP1/S100A11/ARPC5/PAK1/NFE2L2/DOCK5 9 GO:0072594 establishment of protein localization to organelle 21/380 422/18722 0.000157837339275741 0.00205674194410081 PTGS2/SORL1/LRRK2/RAC2/LAPTM5/TXNIP/TSPO/BNIP3L/HCLS1/UBE2D3/STAT3/BID/NUP214/KPNA4/RAB8B/NPEPPS/PPP3CA/SH3GLB1/MAPK1/NCOA4/RAB7A 21 GO:0007162 negative regulation of cell adhesion 17/380 303/18722 0.000164318556405456 0.00213358601355591 PTPRC/PLXNC1/LAPTM5/BCL6/DUSP1/SPI1/PELI1/ARHGDIB/MBP/CEBPB/FGL2/MYADM/LILRB2/PTEN/IRF1/PRKAR1A/PTPN6 17 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 13/380 193/18722 0.000165054744723494 0.00213358601355591 PTPRC/NCF1/LYN/OSM/IL6R/ARRB2/PECAM1/IQGAP1/CLEC7A/HCLS1/CD44/RICTOR/PAK2 13 GO:0034340 response to type I interferon 7/380 58/18722 0.000165673166306401 0.00213358601355591 IFITM2/IFITM1/JAK1/PTPN6/ADAR/IFNAR1/IFITM3 7 GO:1904407 positive regulation of nitric oxide metabolic process 6/380 41/18722 0.000165749657251451 0.00213358601355591 PTGS2/AIF1/KLF2/IL1B/CLEC7A/HBB 6 GO:0031098 stress-activated protein kinase signaling cascade 15/380 247/18722 0.000168230578483732 0.00215895909054123 LRRK2/NCF1/LYN/DUSP1/ZFP36/SPI1/TRIB1/RASSF2/IL1B/SDCBP/CLEC7A/ZFP36L1/PYCARD/PJA2/MAPK1 15 GO:0002761 regulation of myeloid leukocyte differentiation 10/380 120/18722 0.000168802435646899 0.00215975321741576 EVI2B/LYN/LILRB3/TYROBP/TRIB1/FOS/RASSF2/CEBPB/ZFP36L1/HCLS1 10 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 8/380 78/18722 0.000181827047604961 0.00231939020062352 PTGS2/PLAUR/CDKN2D/ARRB2/CARD16/CD44/DDX3X/PAK2 8 GO:0043407 negative regulation of MAP kinase activity 7/380 59/18722 0.000184740438430978 0.00234947674701259 RGS2/SORL1/LYN/DUSP1/IL1B/IRAK3/PTPN6 7 GO:0031331 positive regulation of cellular catabolic process 21/380 427/18722 0.000185430985901786 0.00235119827932355 LRRK2/LAPTM5/ZFP36/TRIB1/IL1B/BTG2/PTEN/AGTPBP1/TNFRSF1B/FBXL5/MSN/ZFP36L1/RALB/ZFP36L2/BNIP3L/BID/HIF1A/HSPA1A/SH3GLB1/NRDC/NFE2L2 21 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 5/380 27/18722 0.000187434508298304 0.00236245578167654 PTPRC/LYN/HCK/FGR/PAK1 5 GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 5/380 27/18722 0.000187434508298304 0.00236245578167654 PTPRC/LYN/HCK/FGR/PAK1 5 GO:0015671 oxygen transport 4/380 15/18722 0.000190974663230742 0.00239993382427951 HBA2/HBA1/HBB/HBG2 4 GO:0032386 regulation of intracellular transport 18/380 337/18722 0.000195872211593772 0.00245419768076812 PTGS2/SORL1/LRRK2/LCP1/MX2/RAC2/ITGB2/IL1B/MSN/BNIP3L/HCLS1/UBE2D3/OAZ1/NUP214/NPEPPS/SH3GLB1/PAK1/MAPK1 18 GO:0042542 response to hydrogen peroxide 11/380 146/18722 0.000197697368589571 0.00246975916217355 SOD2/LRRK2/DUSP1/KLF2/TXNIP/HBA2/KDM6B/HBA1/HBB/NFE2L2/CAT 11 GO:0071248 cellular response to metal ion 13/380 197/18722 0.000202135082475966 0.00251777080672269 PTGS2/LRRK2/NCF1/ALOX5AP/JUNB/B2M/FOS/TSPO/IQGAP1/UBE2D3/CPNE3/MAPK1/NFE2L2 13 GO:0048545 response to steroid hormone 18/380 339/18722 0.000210607600535598 0.00261561052278081 PTGS2/ALPL/AIF1/DUSP1/ZFP36/FOS/TXNIP/CYBA/CFLAR/TSPO/ZFP36L1/ZFP36L2/TGFBR2/NCOA1/TAF7/DDX5/PAK1/NCOA4 18 GO:0097237 cellular response to toxic substance 10/380 124/18722 0.000220940884164417 0.00273592001297166 S100A9/SOD2/PTGS2/ALOX5AP/HBA2/HBA1/HBB/HBG2/NFE2L2/CAT 10 GO:0031342 negative regulation of cell killing 5/380 28/18722 0.000224409825712798 0.00275806999820127 PTPRC/HLA-B/HLA-E/ARRB2/HLA-A 5 GO:0034123 positive regulation of toll-like receptor signaling pathway 5/380 28/18722 0.000224409825712798 0.00275806999820127 PELI1/TLR1/CYBA/PJA2/DDX3X 5 GO:0071241 cellular response to inorganic substance 14/380 226/18722 0.00022468338828322 0.00275806999820127 PTGS2/LRRK2/NCF1/ALOX5AP/JUNB/B2M/FOS/CFLAR/TSPO/IQGAP1/UBE2D3/CPNE3/MAPK1/NFE2L2 14 GO:0045765 regulation of angiogenesis 18/380 342/18722 0.000234526977540542 0.00286969782720846 CXCL8/CXCR2/C5AR1/LRG1/KLF2/ITGAX/PRKCB/ALOX5/IL1B/CXCR4/GLUL/EGLN1/JAK1/STAT3/TGFBR2/BTG1/HIF1A/NFE2L2 18 GO:0046777 protein autophosphorylation 14/380 227/18722 0.000235132265889335 0.00286969782720846 PTPRC/LRRK2/LYN/HCK/RASSF2/FGR/IRAK3/STK17B/IQGAP1/STK4/DDX3X/PAK2/PAK1/NBN 14 GO:1903533 regulation of protein targeting 8/380 81/18722 0.000236623523784114 0.00287134849061811 LRRK2/RAC2/ITGB2/BNIP3L/UBE2D3/NPEPPS/SH3GLB1/PAK1 8 GO:2000106 regulation of leukocyte apoptotic process 8/380 81/18722 0.000236623523784114 0.00287134849061811 CXCR2/LYN/HCAR2/BCL6/TSC22D3/PTEN/HCLS1/HIF1A 8 GO:1903214 regulation of protein targeting to mitochondrion 6/380 44/18722 0.000247231108860153 0.00299067651890939 LRRK2/RAC2/BNIP3L/UBE2D3/NPEPPS/SH3GLB1 6 GO:0045639 positive regulation of myeloid cell differentiation 9/380 103/18722 0.000248974412401452 0.00299067651890939 EVI2B/TYROBP/TRIB1/FOS/ZFP36L1/HCLS1/STAT3/HIF1A/HSPA1A 9 GO:0051238 sequestering of metal ion 4/380 16/18722 0.000250570116889069 0.00299067651890939 S100A8/S100A9/FTH1/FTL 4 GO:1904683 regulation of metalloendopeptidase activity 4/380 16/18722 0.000250570116889069 0.00299067651890939 SORL1/MBP/PICALM/STAT3 4 GO:0032615 interleukin-12 production 7/380 62/18722 0.000252812796639802 0.00299067651890939 LTB/HLA-B/LAPTM5/IRAK3/ARRB2/CLEC7A/IRF1 7 GO:0032655 regulation of interleukin-12 production 7/380 62/18722 0.000252812796639802 0.00299067651890939 LTB/HLA-B/LAPTM5/IRAK3/ARRB2/CLEC7A/IRF1 7 GO:0032731 positive regulation of interleukin-1 beta production 7/380 62/18722 0.000252812796639802 0.00299067651890939 MNDA/TYROBP/CLEC7A/EGR1/PYCARD/IFI16/STAT3 7 GO:0045428 regulation of nitric oxide biosynthetic process 7/380 62/18722 0.000252812796639802 0.00299067651890939 PTGS2/AIF1/KLF2/IL1B/TSPO/CLEC7A/HBB 7 GO:0045576 mast cell activation 7/380 62/18722 0.000252812796639802 0.00299067651890939 S100A12/LYN/ADGRE2/RAC2/FGR/LCP2/PLSCR1 7 GO:0032388 positive regulation of intracellular transport 13/380 202/18722 0.000258346163658908 0.00304762117853892 PTGS2/SORL1/RAC2/ITGB2/IL1B/MSN/HCLS1/UBE2D3/OAZ1/NPEPPS/SH3GLB1/PAK1/MAPK1 13 GO:0051051 negative regulation of transport 22/380 470/18722 0.000262112630891692 0.00308346386618421 PTGS2/RGS2/LRRK2/OSM/SPI1/CORO1A/PRKCB/CNN2/MIDN/IL1B/LILRB2/PTEN/SDCBP/TNFRSF1B/PLSCR1/PICALM/RAB11FIP1/OAZ1/STXBP3/PPP3CA/VPS4B/RAB7A 22 GO:0043405 regulation of MAP kinase activity 12/380 177/18722 0.000275254301911013 0.00322909132574277 S100A12/RGS2/SORL1/LRRK2/LYN/DUSP1/TRIB1/IL1B/IRAK3/IQGAP1/PTPN6/PAK1 12 GO:0010639 negative regulation of organelle organization 18/380 347/18722 0.000279681925255313 0.00327196948468577 LRRK2/GMFG/TMSB4X/DUSP1/CORO1A/WAS/ARRB2/MYADM/TSPO/LILRB2/SSH2/CAPZA1/PRKAR1A/HSPA1A/PAK2/TMOD3/NBN/RAB7A 18 GO:1901342 regulation of vasculature development 18/380 348/18722 0.000289569966219123 0.00337831627255644 CXCL8/CXCR2/C5AR1/LRG1/KLF2/ITGAX/PRKCB/ALOX5/IL1B/CXCR4/GLUL/EGLN1/JAK1/STAT3/TGFBR2/BTG1/HIF1A/NFE2L2 18 GO:0031667 response to nutrient levels 22/380 474/18722 0.000294609812952607 0.00342767186223706 NAMPT/SOD2/PTGS2/SORL1/LRRK2/ACSL1/ALPL/ZFP36/CDKN2D/CYBA/TSPO/PTEN/GLUL/IFI16/RALB/TGFBR2/NCOA1/CPEB4/SH3GLB1/MAPK1/NFE2L2/CAT 22 GO:0030888 regulation of B cell proliferation 7/380 64/18722 0.00030846002870234 0.00355947744292755 MNDA/PTPRC/LYN/TYROBP/BCL6/PELI1/TNFSF13B 7 GO:0080164 regulation of nitric oxide metabolic process 7/380 64/18722 0.00030846002870234 0.00355947744292755 PTGS2/AIF1/KLF2/IL1B/TSPO/CLEC7A/HBB 7 GO:1903409 reactive oxygen species biosynthetic process 7/380 64/18722 0.00030846002870234 0.00355947744292755 SOD2/NCF1/ALOX5/CYBA/CFLAR/RAB27A/STAT3 7 GO:0002449 lymphocyte mediated immunity 18/380 350/18722 0.000310262861242596 0.00356087592781136 PTPRC/FCER1G/HLA-B/BCL6/B2M/CORO1A/LYST/HLA-E/WAS/IL1B/ARRB2/HLA-A/RAB27A/TNFRSF1B/CD55/PTPN6/STX7/NBN 18 GO:0042742 defense response to bacterium 18/380 350/18722 0.000310262861242596 0.00356087592781136 S100A8/S100A12/S100A9/C5AR1/PGLYRP1/FCER1G/FPR2/TREM1/SLC11A1/LYST/IL6R/HLA-E/FGR/CYBA/CEBPB/HLA-A/PYCARD/LYZ 18 GO:0009636 response to toxic substance 15/380 262/18722 0.000317718781194943 0.00363659199556914 S100A9/SOD2/PTGS2/LYN/ALOX5AP/FOS/MBP/HBA2/KDM6B/HBA1/HBB/HBG2/MAPK1/NFE2L2/CAT 15 GO:0048660 regulation of smooth muscle cell proliferation 12/380 180/18722 0.000321087578638746 0.00366524500144229 NAMPT/SOD2/PTGS2/AIF1/TRIB1/IL6R/CYBA/PTEN/TGFBR2/NQO2/SF1/PAK1 12 GO:0016045 detection of bacterium 4/380 17/18722 0.000322444030848857 0.00367083459850782 PGLYRP1/HLA-B/TLR1/HLA-A 4 GO:0007229 integrin-mediated signaling pathway 9/380 107/18722 0.000331352034214816 0.00375207450507954 CD177/PLEK/HCK/ITGAX/FGR/ITGB2/ZYX/MYH9/CUL3 9 GO:0031532 actin cytoskeleton reorganization 9/380 107/18722 0.000331352034214816 0.00375207450507954 GMFG/PLEK/HCK/ARHGDIB/GPR65/HCLS1/RICTOR/MYH9/PAK1 9 GO:0006979 response to oxidative stress 21/380 446/18722 0.000332989292262024 0.00376055907394579 SOD2/PTGS2/LRRK2/NCF1/AIF1/DUSP1/FOS/KLF2/TXNIP/MCL1/ALOX5/HBA2/KDM6B/HBA1/HBB/BTG1/HIF1A/HSPA1A/MAPK1/NFE2L2/CAT 21 GO:0016032 viral process 20/380 415/18722 0.000341371737717735 0.00384497156711332 IFITM2/CXCL8/IFITM1/ZFP36/APOBEC3A/ATG16L2/CXCR4/FCN1/IFI16/IGF2R/PLSCR1/CD55/DDX3X/ADAR/DDX5/HSPA1A/VPS4B/N4BP1/RAB7A/IFITM3 20 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 15/380 264/18722 0.000344434450797641 0.00386917745126793 PTPRC/NCF1/LYN/OSM/IL6R/ITGB2/ARRB2/PECAM1/IQGAP1/CLEC7A/HCLS1/CD44/RICTOR/PTPN6/PAK2 15 GO:0043410 positive regulation of MAPK cascade 22/380 480/18722 0.00034999516684609 0.00392124214707193 S100A12/PTPRC/LRRK2/NCF1/C5AR1/FPR2/OSM/LAPTM5/SPI1/RASSF2/IL1B/ARRB2/CFLAR/PTEN/SDCBP/IQGAP1/CLEC7A/PYCARD/CD44/PJA2/NQO2/PAK1 22 GO:0097028 dendritic cell differentiation 6/380 47/18722 0.000357318616372859 0.00399272913018221 LYN/HLA-B/SPI1/CEBPB/LILRB2/TGFBR2 6 GO:0007034 vacuolar transport 11/380 157/18722 0.000370853046765864 0.0041006857782074 SORL1/LRRK2/LAPTM5/LYST/DENND3/IGF2R/HSPA1A/VPS4B/TMEM50A/NCOA4/RAB7A 11 GO:0051017 actin filament bundle assembly 11/380 157/18722 0.000370853046765864 0.0041006857782074 LCP1/AIF1/PLEK/MARCKS/WAS/GPR65/ZYX/ACTN1/CUL3/PAK2/PAK1 11 GO:1902107 positive regulation of leukocyte differentiation 11/380 157/18722 0.000370853046765864 0.0041006857782074 PTPRC/EVI2B/TYROBP/BCL6/TRIB1/FOS/LILRB2/ZFP36L1/NFKBIZ/HCLS1/TGFBR2 11 GO:1903708 positive regulation of hemopoiesis 11/380 157/18722 0.000370853046765864 0.0041006857782074 PTPRC/EVI2B/TYROBP/BCL6/TRIB1/FOS/LILRB2/ZFP36L1/NFKBIZ/HCLS1/TGFBR2 11 GO:0031396 regulation of protein ubiquitination 13/380 210/18722 0.000375979558882128 0.00414654539548389 LRRK2/LAPTM5/PELI1/IVNS1ABP/RASSF5/ARRB2/TSPO/PTEN/UBE2D1/DDX3X/HSPA1A/CUL3/N4BP1 13 GO:0001776 leukocyte homeostasis 8/380 87/18722 0.000386917413080608 0.00425609154388668 CXCR2/LYN/HCAR2/CORO1A/TSC22D3/TNFSF13B/SOS2/HIF1A 8 GO:0048659 smooth muscle cell proliferation 12/380 184/18722 0.000392132330922646 0.00430228088460467 NAMPT/SOD2/PTGS2/AIF1/TRIB1/IL6R/CYBA/PTEN/TGFBR2/NQO2/SF1/PAK1 12 GO:0001818 negative regulation of cytokine production 18/380 357/18722 0.00039315840915784 0.00430239241029315 SRGN/PTPRC/PGLYRP1/TYROBP/TMSB4X/LAPTM5/BCL6/ZFP36/SLC11A1/KLF2/IRAK3/ARRB2/TSPO/PYCARD/CARD16/PTPN6/DICER1/N4BP1 18 GO:0051403 stress-activated MAPK cascade 14/380 239/18722 0.000397019414943728 0.0043334464491925 LRRK2/NCF1/DUSP1/ZFP36/SPI1/TRIB1/RASSF2/IL1B/SDCBP/CLEC7A/ZFP36L1/PYCARD/PJA2/MAPK1 14 GO:0002673 regulation of acute inflammatory response 6/380 48/18722 0.000401467845229463 0.00437073605281948 PTGS2/FFAR2/OSM/ALOX5AP/HLA-E/IL1B 6 GO:0014812 muscle cell migration 9/380 110/18722 0.000406915020813204 0.00438510735292093 SORL1/AIF1/TRIB1/IQGAP1/S100A11/ARPC5/PAK1/NFE2L2/DOCK5 9 GO:0032611 interleukin-1 beta production 9/380 110/18722 0.000406915020813204 0.00438510735292093 MNDA/TYROBP/ARRB2/CLEC7A/EGR1/PYCARD/IFI16/CARD16/STAT3 9 GO:0032651 regulation of interleukin-1 beta production 9/380 110/18722 0.000406915020813204 0.00438510735292093 MNDA/TYROBP/ARRB2/CLEC7A/EGR1/PYCARD/IFI16/CARD16/STAT3 9 GO:0002643 regulation of tolerance induction 4/380 18/18722 0.000407965123270565 0.00438510735292093 HLA-B/IRAK3/LILRB2/TGFBR2 4 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 4/380 18/18722 0.000407965123270565 0.00438510735292093 HLA-B/HLA-E/ARRB2/HLA-A 4 GO:0070527 platelet aggregation 7/380 67/18722 0.000409949045975094 0.00439527648026462 LYN/PLEK/ACTB/HBB/PTPN6/STXBP3/MYH9 7 GO:0030101 natural killer cell activation 8/380 88/18722 0.000418211556060022 0.00447254025230857 PTPRC/PGLYRP1/TYROBP/CORO1A/HLA-E/FGR/RAB27A/NFIL3 8 GO:0042744 hydrogen peroxide catabolic process 5/380 32/18722 0.00043019800580166 0.00458121381981388 HBA2/HBA1/HBB/HBG2/CAT 5 GO:0051651 maintenance of location in cell 13/380 213/18722 0.000430536741507892 0.00458121381981388 S100A8/S100A9/SRGN/PTPRC/SORL1/LYN/TMSB4X/FTH1/FTL/CORO1A/CYBA/TSPO/PTPN6 13 GO:0070371 ERK1 and ERK2 cascade 17/380 330/18722 0.000444070374498803 0.00471337853634694 PTPRC/C5AR1/LYN/FPR2/DUSP1/IL1B/ARRB2/CFLAR/PTEN/ZFP36L1/PYCARD/ZFP36L2/CD44/YWHAZ/NQO2/PTPN6/MAPK1 17 GO:0046686 response to cadmium ion 7/380 68/18722 0.000449148754023984 0.00474999792278422 SOD2/NCF1/B2M/FOS/UBE2D3/MAPK1/CAT 7 GO:0070849 response to epidermal growth factor 6/380 49/18722 0.000449763675805542 0.00474999792278422 ZFP36/CFLAR/IQGAP1/ZFP36L1/ZFP36L2/MAPK1 6 GO:0014910 regulation of smooth muscle cell migration 8/380 89/18722 0.000451531400337723 0.00475680467768721 SORL1/AIF1/TRIB1/IQGAP1/S100A11/PAK1/NFE2L2/DOCK5 8 GO:0061572 actin filament bundle organization 11/380 161/18722 0.000459373446766216 0.00482741078673679 LCP1/AIF1/PLEK/MARCKS/WAS/GPR65/ZYX/ACTN1/CUL3/PAK2/PAK1 11 GO:0031623 receptor internalization 9/380 113/18722 0.000496128569939308 0.00518126082840959 CXCL8/CXCR2/FCER1G/CXCR1/ITGB2/ARRB2/SDCBP/NUMB/PICALM 9 GO:0071347 cellular response to interleukin-1 9/380 113/18722 0.000496128569939308 0.00518126082840959 CXCL8/KLF2/CEBPB/IL1B/IRAK3/EGR1/PYCARD/HIF1A/USP10 9 GO:0051222 positive regulation of protein transport 16/380 303/18722 0.000496715914128523 0.00518126082840959 PTGS2/SORL1/HCAR2/RAC2/ITGB2/IL1B/GLUL/HCLS1/UBE2D3/NADK/OAZ1/HIF1A/NPEPPS/SH3GLB1/PAK1/MAPK1 16 GO:0036336 dendritic cell migration 5/380 33/18722 0.00049865965206727 0.00518875583907835 CXCR2/CXCR1/SPI1/ALOX5/CXCR4 5 GO:0038093 Fc receptor signaling pathway 6/380 50/18722 0.000502470433717882 0.00520284177700545 PTPRC/FCER1G/LYN/HCK/FGR/PAK1 6 GO:1903747 regulation of establishment of protein localization to mitochondrion 6/380 50/18722 0.000502470433717882 0.00520284177700545 LRRK2/RAC2/BNIP3L/UBE2D3/NPEPPS/SH3GLB1 6 GO:0002523 leukocyte migration involved in inflammatory response 4/380 19/18722 0.000508527393281583 0.00522044802109491 S100A8/S100A9/FFAR2/ALOX5 4 GO:0002716 negative regulation of natural killer cell mediated immunity 4/380 19/18722 0.000508527393281583 0.00522044802109491 HLA-B/HLA-E/ARRB2/HLA-A 4 GO:0061760 antifungal innate immune response 4/380 19/18722 0.000508527393281583 0.00522044802109491 SPI1/CLEC4E/CLEC7A/USP15 4 GO:0042113 B cell activation 17/380 334/18722 0.000509101542553058 0.00522044802109491 MNDA/PTPRC/LYN/TYROBP/LAPTM5/BCL6/SPI1/PELI1/SKAP2/NFAM1/PRKCB/KLF6/ZFP36L1/TNFSF13B/ZFP36L2/PTPN6/NBN 17 GO:0009410 response to xenobiotic stimulus 21/380 462/18722 0.00052856500169262 0.00540471031603914 S100A12/SOD2/PTGS2/ACSL1/LYN/RNF149/B2M/FOS/TXNIP/APOBEC3A/CYBA/IL1B/TSPO/PTEN/CXCR4/STAT3/TGFBR2/UBE2B/NCOA1/NFE2L2/CAT 21 GO:0031668 cellular response to extracellular stimulus 14/380 246/18722 0.000529623324948346 0.00540471031603914 NAMPT/PTPRC/LRRK2/LYN/AIF1/FOS/GLUL/IFI16/RALB/NCOA1/CPEB4/SH3GLB1/MAPK1/NFE2L2 14 GO:1903829 positive regulation of cellular protein localization 15/380 276/18722 0.000548856823142564 0.0055875207836749 PTGS2/SORL1/TYROBP/RAC2/ITGB2/IQGAP1/MSN/STX3/HCLS1/UBE2D3/RHOG/NPEPPS/SH3GLB1/PAK1/MAPK1 15 GO:0062197 cellular response to chemical stress 17/380 337/18722 0.000563109427824568 0.00571497950528199 SOD2/PTGS2/LRRK2/NCF1/AIF1/FOS/KLF2/MCL1/ALOX5/KDM6B/TSPO/ZFP36L1/DDX3X/HIF1A/HSPA1A/MAPK1/NFE2L2 17 GO:0071675 regulation of mononuclear cell migration 9/380 115/18722 0.000564075899222638 0.00571497950528199 C5AR1/LYN/FPR2/AIF1/DUSP1/SPI1/MSN/PYCARD/MAPK1 9 GO:0002446 neutrophil mediated immunity 5/380 34/18722 0.000575001105845862 0.00578415601723807 CD177/TREM1/SPI1/ITGB2/STXBP3 5 GO:0030851 granulocyte differentiation 5/380 34/18722 0.000575001105845862 0.00578415601723807 EVI2B/SPI1/TRIB1/LBR/HCLS1 5 GO:0050869 negative regulation of B cell activation 5/380 34/18722 0.000575001105845862 0.00578415601723807 MNDA/LYN/TYROBP/LAPTM5/BCL6 5 GO:0061515 myeloid cell development 7/380 71/18722 0.000584979826355003 0.0058705913853399 EVI2B/TYROBP/BCL6/KLF2/PTBP3/PTPN6/TMOD3 7 GO:0035196 production of miRNAs involved in gene silencing by miRNA 6/380 52/18722 0.000622214037147569 0.00618967363236958 STAT3/DDX3X/DICER1/ADAR/DDX5/PPP3CA 6 GO:0060147 regulation of posttranscriptional gene silencing 6/380 52/18722 0.000622214037147569 0.00618967363236958 NEAT1/ZFP36/STAT3/ADAR/DDX5/PPP3CA 6 GO:1903426 regulation of reactive oxygen species biosynthetic process 6/380 52/18722 0.000622214037147569 0.00618967363236958 SOD2/ALOX5/CYBA/CFLAR/RAB27A/STAT3 6 GO:0010042 response to manganese ion 4/380 20/18722 0.000625544348206418 0.00618967363236958 SOD2/PTGS2/LRRK2/TSPO 4 GO:0015669 gas transport 4/380 20/18722 0.000625544348206418 0.00618967363236958 HBA2/HBA1/HBB/HBG2 4 GO:1990182 exosomal secretion 4/380 20/18722 0.000625544348206418 0.00618967363236958 SDCBP/RAB27A/VPS4B/RAB7A 4 GO:0002534 cytokine production involved in inflammatory response 7/380 72/18722 0.00063686947254402 0.00627242375866029 GPSM3/ALOX5/IL17RA/CLEC7A/PYCARD/STAT3/HIF1A 7 GO:1900015 regulation of cytokine production involved in inflammatory response 7/380 72/18722 0.00063686947254402 0.00627242375866029 GPSM3/ALOX5/IL17RA/CLEC7A/PYCARD/STAT3/HIF1A 7 GO:0002702 positive regulation of production of molecular mediator of immune response 9/380 117/18722 0.000639463889769221 0.00628336327882286 PTPRC/FFAR2/LAPTM5/B2M/HLA-E/IL1B/HLA-A/CLEC7A/CD55 9 GO:0019932 second-messenger-mediated signaling 16/380 312/18722 0.000681134317007079 0.00667732368640042 CXCL8/RGS2/PTPRC/CXCR2/FPR1/LRRK2/FPR2/CXCR1/PLEK/CXCR4/CLEC7A/CAP1/MCTP2/UBE2B/PPP3CA/TMBIM4 16 GO:0070555 response to interleukin-1 10/380 143/18722 0.000688988335994118 0.00671582401552532 CXCL8/KLF2/CYBA/CEBPB/IL1B/IRAK3/EGR1/PYCARD/HIF1A/USP10 10 GO:0022408 negative regulation of cell-cell adhesion 12/380 196/18722 0.000689730049085105 0.00671582401552532 LAPTM5/BCL6/SPI1/PELI1/MBP/CEBPB/FGL2/MYADM/LILRB2/IRF1/PRKAR1A/PTPN6 12 GO:0060966 regulation of gene silencing by RNA 6/380 53/18722 0.000689818995691502 0.00671582401552532 NEAT1/ZFP36/STAT3/ADAR/DDX5/PPP3CA 6 GO:0032732 positive regulation of interleukin-1 production 7/380 73/18722 0.000692344221560643 0.00672494903281955 MNDA/TYROBP/CLEC7A/EGR1/PYCARD/IFI16/STAT3 7 GO:0018108 peptidyl-tyrosine phosphorylation 18/380 375/18722 0.000699691606020367 0.00678076419106695 PTPRC/NCF1/LYN/OSM/HCK/IL6R/FGR/ITGB2/ARRB2/PECAM1/IQGAP1/CLEC7A/JAK1/HCLS1/CD44/RICTOR/PTPN6/PAK2 18 GO:0034284 response to monosaccharide 13/380 225/18722 0.000720992854695658 0.00695536387160845 NAMPT/SOD2/PTGS2/TXNIP/CYBA/PTEN/GLUL/EGR1/TGFBR2/NADK/HIF1A/PPP3CA/CAT 13 GO:0050769 positive regulation of neurogenesis 13/380 225/18722 0.000720992854695658 0.00695536387160845 LYN/PLXNC1/IL1B/TSPO/CXCR4/TNFRSF1B/ACTR2/NUMB/NIN/HIF1A/DICER1/MME/PAK1 13 GO:0010821 regulation of mitochondrion organization 10/380 144/18722 0.000727336608997902 0.00698474045148779 LRRK2/PLAUR/ARRB2/TSPO/PYCARD/TNFSF10/BNIP3L/BID/HIF1A/HSPA1A 10 GO:0033135 regulation of peptidyl-serine phosphorylation 10/380 144/18722 0.000727336608997902 0.00698474045148779 PTGS2/OSM/RASSF2/ARRB2/PTEN/STK4/HCLS1/CD44/RICTOR/PAK1 10 GO:0007611 learning or memory 14/380 255/18722 0.000753938548004753 0.0072099262102456 PTGS2/B2M/FOS/CEBPB/BTG2/LILRB2/PTEN/ACTR2/PICALM/PJA2/NQO2/HIF1A/MME/MAPK1 14 GO:0050864 regulation of B cell activation 12/380 198/18722 0.000754190628368076 0.0072099262102456 MNDA/PTPRC/LYN/TYROBP/LAPTM5/BCL6/PELI1/NFAM1/ZFP36L1/TNFSF13B/ZFP36L2/PTPN6 12 GO:0046597 negative regulation of viral entry into host cell 4/380 21/18722 0.000760443586158476 0.00721245754534822 IFITM2/IFITM1/FCN1/IFITM3 4 GO:0097734 extracellular exosome biogenesis 4/380 21/18722 0.000760443586158476 0.00721245754534822 SDCBP/RAB27A/VPS4B/RAB7A 4 GO:0150105 protein localization to cell-cell junction 4/380 21/18722 0.000760443586158476 0.00721245754534822 ACTB/PECAM1/JAK1/PAK2 4 GO:0031050 dsRNA processing 6/380 54/18722 0.000762970715540968 0.00721245754534822 STAT3/DDX3X/DICER1/ADAR/DDX5/PPP3CA 6 GO:0070918 production of small RNA involved in gene silencing by RNA 6/380 54/18722 0.000762970715540968 0.00721245754534822 STAT3/DDX3X/DICER1/ADAR/DDX5/PPP3CA 6 GO:0018212 peptidyl-tyrosine modification 18/380 378/18722 0.00076693403617343 0.00723377648818368 PTPRC/NCF1/LYN/OSM/HCK/IL6R/FGR/ITGB2/ARRB2/PECAM1/IQGAP1/CLEC7A/JAK1/HCLS1/CD44/RICTOR/PTPN6/PAK2 18 GO:0050878 regulation of body fluid levels 18/380 379/18722 0.000790547102385664 0.00742343010776782 FCER1G/LYN/SERPINA1/PLEK/ACTB/PLAUR/WAS/CYBA/RAB27A/HBB/JMJD1C/PLSCR1/NCOA1/PTPN6/HIF1A/STXBP3/MYH9/NFE2L2 18 GO:0051346 negative regulation of hydrolase activity 18/380 379/18722 0.000790547102385664 0.00742343010776782 PTGS2/RGS2/SORL1/LRRK2/SERPINA1/PLAUR/CDKN2D/ARRB2/EGLN1/IFI16/CARD16/BOD1L1/PICALM/CD44/DDX3X/PAK2/PPP1R15A/KDM5A 18 GO:0061614 pri-miRNA transcription by RNA polymerase II 6/380 55/18722 0.000841971809192456 0.00788882878745587 SPI1/FOS/EGR1/STAT3/HIF1A/DDX5 6 GO:1903531 negative regulation of secretion by cell 10/380 147/18722 0.000853073303387008 0.0079751996464547 OSM/SPI1/MIDN/IL1B/TNFRSF1B/RAB11FIP1/STXBP3/PPP3CA/VPS4B/RAB7A 10 GO:0002369 T cell cytokine production 5/380 37/18722 0.00085699911272003 0.00797668404916335 B2M/IL1B/HLA-A/TNFRSF1B/CD55 5 GO:0002724 regulation of T cell cytokine production 5/380 37/18722 0.00085699911272003 0.00797668404916335 B2M/IL1B/HLA-A/TNFRSF1B/CD55 5 GO:1904951 positive regulation of establishment of protein localization 16/380 319/18722 0.00086238159178727 0.00800917991495414 PTGS2/SORL1/HCAR2/RAC2/ITGB2/IL1B/GLUL/HCLS1/UBE2D3/NADK/OAZ1/HIF1A/NPEPPS/SH3GLB1/PAK1/MAPK1 16 GO:0050868 negative regulation of T cell activation 9/380 122/18722 0.000864502908214906 0.00801131250829349 LAPTM5/BCL6/PELI1/CEBPB/FGL2/LILRB2/IRF1/PRKAR1A/PTPN6 9 GO:0001659 temperature homeostasis 11/380 174/18722 0.000877989716727167 0.00811852936755361 G0S2/PTGS2/ACSL1/CEBPB/KDM6B/IL1B/CXCR4/EGR1/STAT3/TLE3/NRDC 11 GO:0006809 nitric oxide biosynthetic process 7/380 76/18722 0.000882039322803396 0.00812051420015735 PTGS2/AIF1/KLF2/IL1B/TSPO/CLEC7A/HBB 7 GO:0014823 response to activity 7/380 76/18722 0.000882039322803396 0.00812051420015735 SOD2/CYBA/KDM6B/PTEN/CXCR4/HIF1A/CAT 7 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 3/380 10/18722 0.000895315802468921 0.00816785302791546 PTPRC/LYN/PLSCR1 3 GO:0072124 regulation of glomerular mesangial cell proliferation 3/380 10/18722 0.000895315802468921 0.00816785302791546 IL6R/CFLAR/EGR1 3 GO:0090647 modulation of age-related behavioral decline 3/380 10/18722 0.000895315802468921 0.00816785302791546 B2M/PICALM/BAZ2B 3 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 3/380 10/18722 0.000895315802468921 0.00816785302791546 SORL1/LYN/PICALM 3 GO:0019722 calcium-mediated signaling 12/380 202/18722 0.000898296435616044 0.00816785302791546 CXCL8/PTPRC/CXCR2/LRRK2/FPR2/CXCR1/PLEK/CXCR4/CLEC7A/MCTP2/PPP3CA/TMBIM4 12 GO:2001056 positive regulation of cysteine-type endopeptidase activity 10/380 148/18722 0.000898753131288926 0.00816785302791546 S100A8/S100A9/LAPTM5/CFLAR/CLEC7A/PYCARD/TNFSF10/IFI16/BID/DDX3X 10 GO:0071375 cellular response to peptide hormone stimulus 15/380 290/18722 0.000910592354917161 0.00825772724427019 SORL1/LYN/PRKCB/CYBA/IL1B/PTPRE/CFLAR/PTEN/ZFP36L1/OSBPL8/STAT3/RAB8B/PHIP/PAK1/NFE2L2 15 GO:0044346 fibroblast apoptotic process 4/380 22/18722 0.000914661718417896 0.00827445608585465 STK17B/BID/BTG1/CUL3 4 GO:0030168 platelet activation 9/380 123/18722 0.000916427972680062 0.00827445608585465 FCER1G/LYN/PLEK/ACTB/HBB/PLSCR1/PTPN6/STXBP3/MYH9 9 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 8/380 99/18722 0.000918772130776789 0.00827445608585465 BCL2A1/CDKN2D/MCL1/TNFRSF1B/PYCARD/IFI16/CD44/BID 8 GO:0052126 movement in host environment 11/380 175/18722 0.00092025237696282 0.00827445608585465 IFITM2/CXCL8/IFITM1/CXCR4/FCN1/PLSCR1/CD55/HSPA1A/VPS4B/RAB7A/IFITM3 11 GO:0051701 biological process involved in interaction with host 12/380 203/18722 0.000937703819748323 0.00841350778947912 IFITM2/CXCL8/PGLYRP1/IFITM1/CXCR4/FCN1/PLSCR1/CD55/HSPA1A/VPS4B/RAB7A/IFITM3 12 GO:0140056 organelle localization by membrane tethering 7/380 77/18722 0.000953636101862412 0.00853836974923322 PLEK/VMP1/STX3/RALB/RAB8B/STX7/STXBP3 7 GO:0002478 antigen processing and presentation of exogenous peptide antigen 5/380 38/18722 0.000970617486719403 0.00867207817775669 FCER1G/CTSS/B2M/HLA-E/HLA-A 5 GO:0006626 protein targeting to mitochondrion 8/380 100/18722 0.000981359175991559 0.00874959181120895 LRRK2/RAC2/TSPO/BNIP3L/UBE2D3/BID/NPEPPS/SH3GLB1 8 GO:0001959 regulation of cytokine-mediated signaling pathway 10/380 150/18722 0.00099614415047716 0.00886275310351003 PTPRC/LAPTM5/IRAK3/CXCR4/PYCARD/CARD16/PTPN6/HIF1A/ADAR/HSPA1A 10 GO:0051235 maintenance of location 16/380 326/18722 0.0010831397345032 0.0096137995338952 S100A8/S100A9/SRGN/PTPRC/SORL1/LYN/FFAR2/TMSB4X/FTH1/FTL/CORO1A/CYBA/IL1B/TSPO/OSBPL8/PTPN6 16 GO:0006622 protein targeting to lysosome 4/380 23/18722 0.00108963961659261 0.0096137995338952 SORL1/LAPTM5/NCOA4/RAB7A 4 GO:0045723 positive regulation of fatty acid biosynthetic process 4/380 23/18722 0.00108963961659261 0.0096137995338952 PTGS2/ELOVL5/IL1B/LPGAT1 4 GO:0140112 extracellular vesicle biogenesis 4/380 23/18722 0.00108963961659261 0.0096137995338952 SDCBP/RAB27A/VPS4B/RAB7A 4 GO:0046621 negative regulation of organ growth 5/380 39/18722 0.00109505405207742 0.00964148422151325 RGS2/PTEN/STK4/TGFBR2/PAK1 5 GO:0098754 detoxification 10/380 152/18722 0.00110201623820614 0.0096826530473091 S100A9/SOD2/PTGS2/ALOX5AP/HBA2/HBA1/HBB/HBG2/NFE2L2/CAT 10 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 7/380 79/18722 0.00111051572622753 0.00973713064300953 NCF1/OSM/FGR/PIK3AP1/HCLS1/PTPN6/CAT 7 GO:0002763 positive regulation of myeloid leukocyte differentiation 6/380 58/18722 0.00111720142013827 0.00974609205577787 EVI2B/TYROBP/TRIB1/FOS/ZFP36L1/HCLS1 6 GO:0006826 iron ion transport 6/380 58/18722 0.00111720142013827 0.00974609205577787 STEAP4/SLC25A37/FTH1/B2M/SLC11A1/FTL 6 GO:0050890 cognition 15/380 296/18722 0.0011184417329653 0.00974609205577787 PTGS2/C5AR1/B2M/FOS/CEBPB/BTG2/LILRB2/PTEN/ACTR2/PICALM/PJA2/NQO2/HIF1A/MME/MAPK1 15 GO:0042176 regulation of protein catabolic process 18/380 391/18722 0.00112627398454522 0.00979418957812939 SORL1/LRRK2/LAPTM5/TRIB1/IL1B/IRAK3/PTEN/SDCBP/AGTPBP1/TNFRSF1B/FBXL5/MSN/OAZ1/HSPA1A/NRDC/NFE2L2/N4BP1/RAB7A 18 GO:0007346 regulation of mitotic cell cycle 20/380 457/18722 0.00113195976228488 0.00982346228130422 AIF1/BCL6/DUSP1/NABP1/IL1B/BTG2/PTEN/SDCBP/IQGAP1/ZFP36L1/ZFP36L2/BID/BTG1/DDX3X/PTPN6/CUL3/VPS4B/PHIP/TMOD3/NBN 20 GO:1901215 negative regulation of neuron death 12/380 208/18722 0.00115699695942944 0.0100202088408664 SOD2/SORL1/LRRK2/C5AR1/CORO1A/CEBPB/ARRB2/BTG2/TNFRSF1B/STAT3/HIF1A/CPEB4 12 GO:0002645 positive regulation of tolerance induction 3/380 11/18722 0.00121259309753215 0.0103776309074946 IRAK3/LILRB2/TGFBR2 3 GO:0033483 gas homeostasis 3/380 11/18722 0.00121259309753215 0.0103776309074946 SOD2/EGLN1/HIF1A 3 GO:0048102 autophagic cell death 3/380 11/18722 0.00121259309753215 0.0103776309074946 LAPTM5/CDKN2D/SH3GLB1 3 GO:0072110 glomerular mesangial cell proliferation 3/380 11/18722 0.00121259309753215 0.0103776309074946 IL6R/CFLAR/EGR1 3 GO:0032612 interleukin-1 production 9/380 128/18722 0.00121542029046454 0.0103776309074946 MNDA/TYROBP/ARRB2/CLEC7A/EGR1/PYCARD/IFI16/CARD16/STAT3 9 GO:0032652 regulation of interleukin-1 production 9/380 128/18722 0.00121542029046454 0.0103776309074946 MNDA/TYROBP/ARRB2/CLEC7A/EGR1/PYCARD/IFI16/CARD16/STAT3 9 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 9/380 128/18722 0.00121542029046454 0.0103776309074946 NCF1/LYN/SPI1/RASSF2/IL1B/SDCBP/CLEC7A/PYCARD/PJA2 9 GO:0001836 release of cytochrome c from mitochondria 6/380 59/18722 0.0012227630407089 0.0103983965409683 SOD2/PLAUR/ARRB2/PYCARD/TNFSF10/BID 6 GO:0048278 vesicle docking 6/380 59/18722 0.0012227630407089 0.0103983965409683 PLEK/STX3/RALB/RAB8B/STX7/STXBP3 6 GO:0150077 regulation of neuroinflammatory response 5/380 40/18722 0.00123092883649474 0.0104259672451105 PTGS2/PTPRC/LRRK2/IL1B/TNFRSF1B 5 GO:1901223 negative regulation of NIK/NF-kappaB signaling 5/380 40/18722 0.00123092883649474 0.0104259672451105 LITAF/TMSB4X/SPI1/RASSF2/DDX3X 5 GO:0046634 regulation of alpha-beta T cell activation 8/380 104/18722 0.00126667767528701 0.0106243376604039 PTPRC/BCL6/HLA-E/HLA-A/IRF1/NFKBIZ/TGFBR2/CD55 8 GO:0048661 positive regulation of smooth muscle cell proliferation 8/380 104/18722 0.00126667767528701 0.0106243376604039 NAMPT/PTGS2/AIF1/IL6R/CYBA/TGFBR2/NQO2/PAK1 8 GO:0071214 cellular response to abiotic stimulus 16/380 331/18722 0.00126865031525369 0.0106243376604039 NAMPT/PTGS2/CNN2/CYBA/IL1B/TSPO/PTEN/ZFP36L1/EGR1/IRF1/IFI16/CARD16/MAP3K2/DDX3X/MME/N4BP1 16 GO:0104004 cellular response to environmental stimulus 16/380 331/18722 0.00126865031525369 0.0106243376604039 NAMPT/PTGS2/CNN2/CYBA/IL1B/TSPO/PTEN/ZFP36L1/EGR1/IRF1/IFI16/CARD16/MAP3K2/DDX3X/MME/N4BP1 16 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 9/380 129/18722 0.00128373836318965 0.0106243376604039 S100A8/S100A9/LAPTM5/CFLAR/CLEC7A/PYCARD/TNFSF10/BID/DDX3X 9 GO:0002726 positive regulation of T cell cytokine production 4/380 24/18722 0.00128681797011384 0.0106243376604039 B2M/IL1B/HLA-A/CD55 4 GO:0035458 cellular response to interferon-beta 4/380 24/18722 0.00128681797011384 0.0106243376604039 IFITM2/MNDA/IRF1/IFI16 4 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 4/380 24/18722 0.00128681797011384 0.0106243376604039 KLF2/CEBPB/HIF1A/NFE2L2 4 GO:0060149 negative regulation of posttranscriptional gene silencing 4/380 24/18722 0.00128681797011384 0.0106243376604039 NEAT1/STAT3/ADAR/PPP3CA 4 GO:0060967 negative regulation of gene silencing by RNA 4/380 24/18722 0.00128681797011384 0.0106243376604039 NEAT1/STAT3/ADAR/PPP3CA 4 GO:0090023 positive regulation of neutrophil chemotaxis 4/380 24/18722 0.00128681797011384 0.0106243376604039 CXCL8/CXCR2/C5AR1/RAC2 4 GO:0046209 nitric oxide metabolic process 7/380 81/18722 0.00128696227149639 0.0106243376604039 PTGS2/AIF1/KLF2/IL1B/TSPO/CLEC7A/HBB 7 GO:0048708 astrocyte differentiation 7/380 81/18722 0.00128696227149639 0.0106243376604039 S100A8/S100A9/C5AR1/FPR2/VIM/STAT3/MAPK1 7 GO:0050767 regulation of neurogenesis 17/380 364/18722 0.00131380174203125 0.0108248061819111 SORL1/LYN/PLXNC1/B2M/IL1B/TSPO/PTEN/CXCR4/TNFRSF1B/ACTR2/NUMB/NIN/HIF1A/DICER1/MME/PPP3CA/PAK1 17 GO:0042063 gliogenesis 15/380 301/18722 0.00132095914117907 0.0108626445881424 S100A8/S100A9/C5AR1/LYN/FPR2/MBOAT7/VIM/IL1B/TSPO/PTEN/CXCR4/TNFRSF1B/STAT3/DICER1/MAPK1 15 GO:0046631 alpha-beta T cell activation 10/380 156/18722 0.00134140404682702 0.0110093917409155 PTPRC/BCL6/IL6R/HLA-E/HLA-A/IRF1/NFKBIZ/STAT3/TGFBR2/CD55 10 GO:1902622 regulation of neutrophil migration 5/380 41/18722 0.00137887038916742 0.0112637342859122 CXCL8/CXCR2/C5AR1/RAC2/RHOG 5 GO:0001892 embryonic placenta development 7/380 82/18722 0.00138303230901402 0.0112637342859122 JUNB/CEBPB/STK4/ZFP36L1/NCOA1/HIF1A/MAPK1 7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 7/380 82/18722 0.00138303230901402 0.0112637342859122 TNFRSF10C/SPI1/CFLAR/PTEN/STK4/BID/DDX3X 7 GO:2001057 reactive nitrogen species metabolic process 7/380 82/18722 0.00138303230901402 0.0112637342859122 PTGS2/AIF1/KLF2/IL1B/TSPO/CLEC7A/HBB 7 GO:0071887 leukocyte apoptotic process 8/380 106/18722 0.00143219184040037 0.0116417129445213 CXCR2/LYN/HCAR2/BCL6/TSC22D3/PTEN/HCLS1/HIF1A 8 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 4/380 25/18722 0.00150763314015287 0.0121615739972331 TRIB1/LY96/CARD16/CD55 4 GO:0072012 glomerulus vasculature development 4/380 25/18722 0.00150763314015287 0.0121615739972331 IL6R/PECAM1/CFLAR/EGR1 4 GO:1903901 negative regulation of viral life cycle 4/380 25/18722 0.00150763314015287 0.0121615739972331 IFITM2/IFITM1/FCN1/IFITM3 4 GO:1905048 regulation of metallopeptidase activity 4/380 25/18722 0.00150763314015287 0.0121615739972331 SORL1/MBP/PICALM/STAT3 4 GO:0008637 apoptotic mitochondrial changes 8/380 107/18722 0.00152114859241536 0.0122472705111769 SOD2/PLAUR/ARRB2/PYCARD/TNFSF10/BNIP3L/BID/HSPA1A 8 GO:0033003 regulation of mast cell activation 5/380 42/18722 0.00153951480833051 0.0123248491744418 LYN/ADGRE2/RAC2/FGR/PLSCR1 5 GO:0033574 response to testosterone 5/380 42/18722 0.00153951480833051 0.0123248491744418 DUSP1/CFLAR/TSPO/MSN/NCOA4 5 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 5/380 42/18722 0.00153951480833051 0.0123248491744418 SPI1/FOS/EGR1/STAT3/HIF1A 5 GO:0002260 lymphocyte homeostasis 6/380 62/18722 0.00158559502310029 0.012583031808528 LYN/CORO1A/TSC22D3/TNFSF13B/SOS2/HIF1A 6 GO:0032835 glomerulus development 6/380 62/18722 0.00158559502310029 0.012583031808528 BASP1/IL6R/PECAM1/CFLAR/IQGAP1/EGR1 6 GO:0010660 regulation of muscle cell apoptotic process 7/380 84/18722 0.00159191707577988 0.012583031808528 SOD2/CXCR2/ARRB2/CFLAR/PTEN/STK4/NFE2L2 7 GO:0002664 regulation of T cell tolerance induction 3/380 12/18722 0.00159256317576647 0.012583031808528 HLA-B/LILRB2/TGFBR2 3 GO:0051639 actin filament network formation 3/380 12/18722 0.00159256317576647 0.012583031808528 LCP1/ARPC5/ACTN1 3 GO:1902563 regulation of neutrophil activation 3/380 12/18722 0.00159256317576647 0.012583031808528 CD177/SPI1/ITGB2 3 GO:1905245 regulation of aspartic-type peptidase activity 3/380 12/18722 0.00159256317576647 0.012583031808528 SORL1/LYN/PICALM 3 GO:0014002 astrocyte development 5/380 43/18722 0.00171350477212062 0.0134632517809478 S100A8/S100A9/C5AR1/FPR2/VIM 5 GO:0031952 regulation of protein autophosphorylation 5/380 43/18722 0.00171350477212062 0.0134632517809478 PTPRC/RASSF2/IQGAP1/DDX3X/NBN 5 GO:0098927 vesicle-mediated transport between endosomal compartments 5/380 43/18722 0.00171350477212062 0.0134632517809478 SORL1/CORO1A/MSN/MAPK1/RAB7A 5 GO:0050854 regulation of antigen receptor-mediated signaling pathway 6/380 63/18722 0.00172307601702514 0.0134961809173037 PTPRC/LYN/LAPTM5/NFAM1/PRKCB/PTPN6 6 GO:0007163 establishment or maintenance of cell polarity 12/380 218/18722 0.00172406939226949 0.0134961809173037 RAC2/ACTB/MSN/ACTR2/CAP1/ARPC5/RHOG/ACTR3/RICTOR/MYH9/PAK1/FLOT2 12 GO:0002407 dendritic cell chemotaxis 4/380 26/18722 0.00175351329656378 0.0136509720789478 CXCR2/CXCR1/SPI1/CXCR4 4 GO:0034114 regulation of heterotypic cell-cell adhesion 4/380 26/18722 0.00175351329656378 0.0136509720789478 MBP/IL1B/MYADM/CD44 4 GO:0070102 interleukin-6-mediated signaling pathway 4/380 26/18722 0.00175351329656378 0.0136509720789478 SPI1/IL6R/JAK1/STAT3 4 GO:0051047 positive regulation of secretion 15/380 310/18722 0.00176328847222194 0.0137018838162567 S100A8/CD177/HCAR2/FGR/ITGB2/CYBA/IL1B/SDCBP/RAB27A/GLUL/NADK/HIF1A/RAB8B/VPS4B/RAB7A 15 GO:0051100 negative regulation of binding 10/380 162/18722 0.0017783796053802 0.0137686245498814 SORL1/LRRK2/TMSB4X/B2M/ACTB/ARRB2/IFI16/CARD16/RALB/PPP3CA 10 GO:0060759 regulation of response to cytokine stimulus 10/380 162/18722 0.0017783796053802 0.0137686245498814 PTPRC/LAPTM5/IRAK3/CXCR4/PYCARD/CARD16/PTPN6/HIF1A/ADAR/HSPA1A 10 GO:0045921 positive regulation of exocytosis 7/380 86/18722 0.00182457136376657 0.0141004739517362 CD177/FGR/ITGB2/SDCBP/RAB27A/VPS4B/RAB7A 7 GO:1900076 regulation of cellular response to insulin stimulus 6/380 64/18722 0.00186941560202404 0.014413307135387 SORL1/PRKCB/IL1B/PTPRE/OSBPL8/PAK1 6 GO:0071560 cellular response to transforming growth factor beta stimulus 13/380 250/18722 0.00187185806953078 0.014413307135387 LRG1/SPI1/FOS/ARRB2/CFLAR/SDCBP/ZFP36L1/ZFP36L2/ZYX/USP15/STAT3/TGFBR2/HSPA1A 13 GO:0051960 regulation of nervous system development 19/380 443/18722 0.0018779829525683 0.0144342246898852 SORL1/LYN/PLXNC1/B2M/ITGAX/IL1B/TSPO/PTEN/CXCR4/TNFRSF1B/ACTR2/TYMP/NUMB/NIN/HIF1A/DICER1/MME/PPP3CA/PAK1 19 GO:0150076 neuroinflammatory response 5/380 44/18722 0.00190148857510273 0.0145620327586982 PTGS2/PTPRC/LRRK2/IL1B/TNFRSF1B 5 GO:1903573 negative regulation of response to endoplasmic reticulum stress 5/380 44/18722 0.00190148857510273 0.0145620327586982 LRRK2/ALOX5/GRINA/HSPA1A/PPP1R15A 5 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 8/380 111/18722 0.00192170360431282 0.0146902793578787 NCF1/OSM/FGR/PTEN/PIK3AP1/HCLS1/PTPN6/CAT 8 GO:0031954 positive regulation of protein autophosphorylation 4/380 27/18722 0.00202587482495777 0.0152860245094915 RASSF2/IQGAP1/DDX3X/NBN 4 GO:0060333 interferon-gamma-mediated signaling pathway 4/380 27/18722 0.00202587482495777 0.0152860245094915 HCK/IRF1/JAK1/IFNGR2 4 GO:0061437 renal system vasculature development 4/380 27/18722 0.00202587482495777 0.0152860245094915 IL6R/PECAM1/CFLAR/EGR1 4 GO:0061440 kidney vasculature development 4/380 27/18722 0.00202587482495777 0.0152860245094915 IL6R/PECAM1/CFLAR/EGR1 4 GO:0071624 positive regulation of granulocyte chemotaxis 4/380 27/18722 0.00202587482495777 0.0152860245094915 CXCL8/CXCR2/C5AR1/RAC2 4 GO:0002430 complement receptor mediated signaling pathway 3/380 13/18722 0.00203933975156143 0.0152860245094915 FPR1/C5AR1/FPR2 3 GO:0036462 TRAIL-activated apoptotic signaling pathway 3/380 13/18722 0.00203933975156143 0.0152860245094915 TNFRSF10C/SPI1/PTEN 3 GO:0071801 regulation of podosome assembly 3/380 13/18722 0.00203933975156143 0.0152860245094915 LCP1/HCK/MSN 3 GO:0072672 neutrophil extravasation 3/380 13/18722 0.00203933975156143 0.0152860245094915 JAML/CD177/PECAM1 3 GO:1902947 regulation of tau-protein kinase activity 3/380 13/18722 0.00203933975156143 0.0152860245094915 SORL1/C5AR1/EGR1 3 GO:2001198 regulation of dendritic cell differentiation 3/380 13/18722 0.00203933975156143 0.0152860245094915 HLA-B/CEBPB/LILRB2 3 GO:0018105 peptidyl-serine phosphorylation 15/380 315/18722 0.00205839103413435 0.015401565423249 PTGS2/LRRK2/OSM/RASSF2/PRKCB/ARRB2/PTEN/STK4/HCLS1/CD44/TGFBR2/RICTOR/PAK2/PAK1/MAPK1 15 GO:0097305 response to alcohol 13/380 253/18722 0.00207868353106779 0.0155259695839014 S100A8/SOD2/RGS2/SPI1/FOS/KLF2/CYBA/TSPO/PTEN/ACTR2/STAT3/TGFBR2/CAT 13 GO:0071364 cellular response to epidermal growth factor stimulus 5/380 45/18722 0.00210411917262815 0.0156882829156342 ZFP36/CFLAR/IQGAP1/ZFP36L1/ZFP36L2 5 GO:0002708 positive regulation of lymphocyte mediated immunity 8/380 113/18722 0.00215092986140646 0.0160091176855121 PTPRC/HLA-B/B2M/HLA-E/IL1B/HLA-A/CD55/STX7 8 GO:0006959 humoral immune response 15/380 317/18722 0.0021874139382141 0.0161870066684021 S100A12/CXCL8/S100A9/PTPRC/PGLYRP1/TREM1/SLC11A1/HLA-E/ALOX5/IL1B/HLA-A/FCN1/LYZ/CD55/PTPN6 15 GO:0070302 regulation of stress-activated protein kinase signaling cascade 11/380 195/18722 0.00218851623647533 0.0161870066684021 NCF1/LYN/DUSP1/SPI1/RASSF2/IL1B/SDCBP/CLEC7A/PYCARD/PJA2/MAPK1 11 GO:0014015 positive regulation of gliogenesis 6/380 66/18722 0.00219011920212382 0.0161870066684021 LYN/IL1B/TSPO/CXCR4/TNFRSF1B/DICER1 6 GO:0046626 regulation of insulin receptor signaling pathway 6/380 66/18722 0.00219011920212382 0.0161870066684021 SORL1/PRKCB/IL1B/PTPRE/OSBPL8/PAK1 6 GO:0010657 muscle cell apoptotic process 7/380 89/18722 0.00222202696025415 0.0163855782523902 SOD2/CXCR2/ARRB2/CFLAR/PTEN/STK4/NFE2L2 7 GO:0031960 response to corticosteroid 10/380 167/18722 0.00222472431998214 0.0163855782523902 PTGS2/ALPL/AIF1/DUSP1/ZFP36/FOS/CYBA/CFLAR/ZFP36L1/ZFP36L2 10 GO:0010001 glial cell differentiation 12/380 225/18722 0.00224353662131896 0.0164954472070934 S100A8/S100A9/C5AR1/LYN/FPR2/VIM/PTEN/CXCR4/TNFRSF1B/STAT3/DICER1/MAPK1 12 GO:0002244 hematopoietic progenitor cell differentiation 8/380 114/18722 0.00227332391967807 0.0166854883879317 PTPRC/OSM/SPI1/PLEK/SOS2/PTPN6/ADAR/NFE2L2 8 GO:0031032 actomyosin structure organization 11/380 196/18722 0.00227763325302286 0.0166881952016467 WAS/CNN2/CFLAR/GPR65/ZYX/PRKAR1A/MYH9/CUL3/PAK2/PAK1/TMOD3 11 GO:0071559 response to transforming growth factor beta 13/380 256/18722 0.00230398315054168 0.0168107746228611 LRG1/SPI1/FOS/ARRB2/CFLAR/SDCBP/ZFP36L1/ZFP36L2/ZYX/USP15/STAT3/TGFBR2/HSPA1A 13 GO:2000107 negative regulation of leukocyte apoptotic process 5/380 46/18722 0.00232205323502126 0.0168107746228611 CXCR2/BCL6/TSC22D3/HCLS1/HIF1A 5 GO:0010575 positive regulation of vascular endothelial growth factor production 4/380 28/18722 0.0023261189914986 0.0168107746228611 PTGS2/C5AR1/IL1B/HIF1A 4 GO:0070076 histone lysine demethylation 4/380 28/18722 0.0023261189914986 0.0168107746228611 KDM6B/JMJD1C/UBE2B/KDM5A 4 GO:0090200 positive regulation of release of cytochrome c from mitochondria 4/380 28/18722 0.0023261189914986 0.0168107746228611 PLAUR/PYCARD/TNFSF10/BID 4 GO:1902624 positive regulation of neutrophil migration 4/380 28/18722 0.0023261189914986 0.0168107746228611 CXCL8/CXCR2/C5AR1/RAC2 4 GO:1903649 regulation of cytoplasmic transport 4/380 28/18722 0.0023261189914986 0.0168107746228611 SORL1/LRRK2/MSN/MAPK1 4 GO:1990776 response to angiotensin 4/380 28/18722 0.0023261189914986 0.0168107746228611 PTGS2/CYBA/IQGAP1/NFE2L2 4 GO:0006879 cellular iron ion homeostasis 6/380 67/18722 0.0023652179060073 0.0169697232670473 STEAP4/FTH1/SLC11A1/FTL/HIF1A/NCOA4 6 GO:0046635 positive regulation of alpha-beta T cell activation 6/380 67/18722 0.0023652179060073 0.0169697232670473 PTPRC/HLA-E/HLA-A/NFKBIZ/TGFBR2/CD55 6 GO:1902117 positive regulation of organelle assembly 6/380 67/18722 0.0023652179060073 0.0169697232670473 LCP1/SDCBP/MSN/RALB/VPS4B/SH3GLB1 6 GO:0030183 B cell differentiation 9/380 141/18722 0.00237215494075372 0.0169697232670473 PTPRC/BCL6/SPI1/NFAM1/KLF6/ZFP36L1/TNFSF13B/ZFP36L2/PTPN6 9 GO:0032355 response to estradiol 9/380 141/18722 0.00237215494075372 0.0169697232670473 PTGS2/DUSP1/TXNIP/CFLAR/PTEN/STAT3/BID/NCOA1/CAT 9 GO:1903038 negative regulation of leukocyte cell-cell adhesion 9/380 141/18722 0.00237215494075372 0.0169697232670473 LAPTM5/BCL6/PELI1/CEBPB/FGL2/LILRB2/IRF1/PRKAR1A/PTPN6 9 GO:0046916 cellular transition metal ion homeostasis 8/380 115/18722 0.0024011181641981 0.0171479518134553 S100A8/S100A9/STEAP4/FTH1/SLC11A1/FTL/HIF1A/NCOA4 8 GO:0044403 biological process involved in symbiotic interaction 14/380 290/18722 0.0025308833297322 0.017986148215124 IFITM2/CXCL8/PGLYRP1/IFITM1/TREM1/CXCR4/FCN1/IGF2R/PLSCR1/CD55/HSPA1A/VPS4B/RAB7A/IFITM3 14 GO:0021782 glial cell development 8/380 116/18722 0.00253447484876655 0.017986148215124 S100A8/S100A9/C5AR1/LYN/FPR2/VIM/PTEN/DICER1 8 GO:0014911 positive regulation of smooth muscle cell migration 5/380 47/18722 0.00255595021343178 0.017986148215124 AIF1/IQGAP1/S100A11/PAK1/DOCK5 5 GO:0019884 antigen processing and presentation of exogenous antigen 5/380 47/18722 0.00255595021343178 0.017986148215124 FCER1G/CTSS/B2M/HLA-E/HLA-A 5 GO:0031641 regulation of myelination 5/380 47/18722 0.00255595021343178 0.017986148215124 ITGAX/PTEN/TNFRSF1B/TYMP/DICER1 5 GO:1900744 regulation of p38MAPK cascade 5/380 47/18722 0.00255595021343178 0.017986148215124 NCF1/DUSP1/SPI1/IL1B/PJA2 5 GO:0002517 T cell tolerance induction 3/380 14/18722 0.00255670867190192 0.017986148215124 HLA-B/LILRB2/TGFBR2 3 GO:0051764 actin crosslink formation 3/380 14/18722 0.00255670867190192 0.017986148215124 LCP1/AIF1/MARCKS 3 GO:1901722 regulation of cell proliferation involved in kidney development 3/380 14/18722 0.00255670867190192 0.017986148215124 IL6R/CFLAR/EGR1 3 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 16/380 355/18722 0.00257552308265982 0.0180884581344351 SORL1/LRG1/SPI1/FOS/VIM/ARRB2/SDCBP/EGR1/UBE2D1/ZYX/USP15/UBE2D3/STAT3/TGFBR2/DDX5/HSPA1A 16 GO:0045444 fat cell differentiation 12/380 229/18722 0.00259366080886571 0.0181856846449442 PTGS2/RGS2/STEAP4/FFAR2/LRG1/ZFP36/ALOX5/CEBPB/STK4/ZFP36L1/OSBPL8/ZFP36L2 12 GO:0051048 negative regulation of secretion 10/380 171/18722 0.00264318805320573 0.0184976779514371 OSM/SPI1/MIDN/IL1B/TNFRSF1B/RAB11FIP1/STXBP3/PPP3CA/VPS4B/RAB7A 10 GO:0060969 negative regulation of gene silencing 4/380 29/18722 0.00265562885347669 0.0184976779514371 NEAT1/STAT3/ADAR/PPP3CA 4 GO:0090025 regulation of monocyte chemotaxis 4/380 29/18722 0.00265562885347669 0.0184976779514371 LYN/FPR2/AIF1/DUSP1 4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4/380 29/18722 0.00265562885347669 0.0184976779514371 SOD2/MCL1/HIF1A/NFE2L2 4 GO:0071902 positive regulation of protein serine/threonine kinase activity 11/380 200/18722 0.00266401035638783 0.0185255892599384 S100A12/LRRK2/ACSL1/IL1B/IQGAP1/STK4/DAZAP2/RALB/RICTOR/DDX3X/PAK1 11 GO:0051656 establishment of organelle localization 17/380 390/18722 0.00270951775726475 0.0188111601672397 LRRK2/LYN/MYO1F/ADGRE2/RAC2/FGR/RAB27A/AGTPBP1/ACTR2/PICALM/ACTR3/UBE2B/YWHAZ/HIF1A/MYH9/CUL3/VPS4B 17 GO:0001890 placenta development 9/380 144/18722 0.0027348704234896 0.0189251245808471 PTGS2/JUNB/CEBPB/STK4/ZFP36L1/NCOA1/HIF1A/MME/MAPK1 9 GO:0014065 phosphatidylinositol 3-kinase signaling 9/380 144/18722 0.0027348704234896 0.0189251245808471 NCF1/OSM/FGR/PTEN/ZFP36L1/PIK3AP1/HCLS1/PTPN6/CAT 9 GO:0090199 regulation of release of cytochrome c from mitochondria 5/380 48/18722 0.0028064714190367 0.0193889175523988 PLAUR/ARRB2/PYCARD/TNFSF10/BID 5 GO:0032088 negative regulation of NF-kappaB transcription factor activity 7/380 93/18722 0.00285218476204499 0.0196726424548217 TMSB4X/SPI1/PELI1/IRAK3/ARRB2/PYCARD/CAT 7 GO:0046879 hormone secretion 14/380 295/18722 0.00295347019172311 0.0203086554289224 LYN/FFAR2/OSM/HCAR2/ALOX5/MIDN/IL1B/GLUL/RAB11FIP1/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 14 GO:0002548 monocyte chemotaxis 6/380 70/18722 0.00295398624420689 0.0203086554289224 S100A12/LYN/FPR2/AIF1/DUSP1/IL6R 6 GO:0031398 positive regulation of protein ubiquitination 8/380 119/18722 0.00296957164435222 0.020382716229873 LRRK2/LAPTM5/PELI1/RASSF5/PTEN/UBE2D1/DDX3X/CUL3 8 GO:0032869 cellular response to insulin stimulus 11/380 203/18722 0.00298719761160064 0.0204705208497228 SORL1/PRKCB/IL1B/PTPRE/CFLAR/PTEN/ZFP36L1/OSBPL8/RAB8B/PHIP/PAK1 11 GO:0007584 response to nutrient 10/380 174/18722 0.00299660545199993 0.0205018159761223 SOD2/PTGS2/ACSL1/ALPL/CDKN2D/TSPO/PTEN/TGFBR2/NCOA1/CAT 10 GO:0043304 regulation of mast cell degranulation 4/380 30/18722 0.00301576640417178 0.0205664584889975 LYN/ADGRE2/RAC2/FGR 4 GO:0045577 regulation of B cell differentiation 4/380 30/18722 0.00301576640417178 0.0205664584889975 NFAM1/ZFP36L1/ZFP36L2/PTPN6 4 GO:0030316 osteoclast differentiation 7/380 94/18722 0.00302921144665703 0.0205918306205337 LILRB3/TYROBP/JUNB/FOS/RASSF2/CEBPB/SNX10 7 GO:0032091 negative regulation of protein binding 7/380 94/18722 0.00302921144665703 0.0205918306205337 SORL1/LRRK2/B2M/ACTB/ARRB2/CARD16/RALB 7 GO:0052372 modulation by symbiont of entry into host 5/380 49/18722 0.00307427911713115 0.0208313152976807 IFITM2/CXCL8/IFITM1/FCN1/IFITM3 5 GO:0060964 regulation of gene silencing by miRNA 5/380 49/18722 0.00307427911713115 0.0208313152976807 NEAT1/ZFP36/STAT3/DDX5/PPP3CA 5 GO:0072655 establishment of protein localization to mitochondrion 8/380 120/18722 0.0031268396222128 0.0211536194889317 LRRK2/RAC2/TSPO/BNIP3L/UBE2D3/BID/NPEPPS/SH3GLB1 8 GO:0030852 regulation of granulocyte differentiation 3/380 15/18722 0.00314814217406972 0.0211625112812464 EVI2B/TRIB1/HCLS1 3 GO:0045986 negative regulation of smooth muscle contraction 3/380 15/18722 0.00314814217406972 0.0211625112812464 PTGS2/RGS2/DOCK5 3 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3/380 15/18722 0.00314814217406972 0.0211625112812464 ZFP36/ZFP36L1/ZFP36L2 3 GO:1903543 positive regulation of exosomal secretion 3/380 15/18722 0.00314814217406972 0.0211625112812464 SDCBP/VPS4B/RAB7A 3 GO:0031647 regulation of protein stability 14/380 298/18722 0.00323369153973567 0.0217031436937885 LRRK2/TYROBP/RNF149/RASSF2/PTEN/STK4/PYCARD/CMTM6/UBE2B/HSPA1A/CUL3/SH3GLB1/MAPK1/FLOT2 14 GO:0051384 response to glucocorticoid 9/380 148/18722 0.00328526880727114 0.0219799841139279 PTGS2/ALPL/AIF1/DUSP1/ZFP36/FOS/CFLAR/ZFP36L1/ZFP36L2 9 GO:0043500 muscle adaptation 8/380 121/18722 0.00329051001847232 0.0219799841139279 RGS2/AIF1/CYBA/IL1B/CFLAR/TNFRSF1B/PPP3CA/PAK1 8 GO:1904019 epithelial cell apoptotic process 8/380 121/18722 0.00329051001847232 0.0219799841139279 ZFP36/ARRB2/CFLAR/STK4/ZFP36L1/TGFBR2/BID/NFE2L2 8 GO:0001782 B cell homeostasis 4/380 31/18722 0.0034078699409511 0.0225858046947228 LYN/TNFSF13B/SOS2/HIF1A 4 GO:0016577 histone demethylation 4/380 31/18722 0.0034078699409511 0.0225858046947228 KDM6B/JMJD1C/UBE2B/KDM5A 4 GO:0033006 regulation of mast cell activation involved in immune response 4/380 31/18722 0.0034078699409511 0.0225858046947228 LYN/ADGRE2/RAC2/FGR 4 GO:0055022 negative regulation of cardiac muscle tissue growth 4/380 31/18722 0.0034078699409511 0.0225858046947228 RGS2/PTEN/TGFBR2/PAK1 4 GO:0061117 negative regulation of heart growth 4/380 31/18722 0.0034078699409511 0.0225858046947228 RGS2/PTEN/TGFBR2/PAK1 4 GO:0016050 vesicle organization 14/380 300/18722 0.00343232508827087 0.0227123386700424 SRGN/CORO1A/LYST/SNX10/SDCBP/RAB27A/STX3/SAMD9/PICALM/RAB8B/STX7/CUL3/VPS4B/RAB7A 14 GO:0019730 antimicrobial humoral response 8/380 122/18722 0.00346075613147284 0.0228647460480304 S100A12/CXCL8/S100A9/PGLYRP1/SLC11A1/HLA-E/HLA-A/LYZ 8 GO:0006913 nucleocytoplasmic transport 14/380 301/18722 0.00353531854910462 0.0232847185932474 PTGS2/LRRK2/MX2/TXNIP/IL1B/XPO6/ANP32A/HCLS1/STAT3/NUP214/KPNA4/PPP3CA/MAPK1/ZC3H11A 14 GO:0051169 nuclear transport 14/380 301/18722 0.00353531854910462 0.0232847185932474 PTGS2/LRRK2/MX2/TXNIP/IL1B/XPO6/ANP32A/HCLS1/STAT3/NUP214/KPNA4/PPP3CA/MAPK1/ZC3H11A 14 GO:1901216 positive regulation of neuron death 7/380 97/18722 0.00361098824885943 0.0237461727234778 TYROBP/FOS/MCL1/ITGB2/EGR1/PICALM/NQO2 7 GO:0070988 demethylation 6/380 73/18722 0.00364595286754313 0.0239389308434808 APOBEC3A/KDM6B/JMJD1C/UBE2B/KDM5A/TET2 6 GO:0071622 regulation of granulocyte chemotaxis 5/380 51/18722 0.00366440250241503 0.0240228244546867 CXCL8/CXCR2/C5AR1/RAC2/MAPK1 5 GO:0044409 entry into host 9/380 151/18722 0.00375253281839296 0.024448525181767 IFITM2/CXCL8/IFITM1/CXCR4/FCN1/PLSCR1/CD55/HSPA1A/IFITM3 9 GO:0043409 negative regulation of MAPK cascade 10/380 180/18722 0.00381624089825238 0.024448525181767 RGS2/PTPRC/SORL1/LYN/RNF149/DUSP1/IL1B/IRAK3/PTEN/PTPN6 10 GO:0002713 negative regulation of B cell mediated immunity 3/380 16/18722 0.00381681264880371 0.024448525181767 BCL6/CD55/PTPN6 3 GO:0002890 negative regulation of immunoglobulin mediated immune response 3/380 16/18722 0.00381681264880371 0.024448525181767 BCL6/CD55/PTPN6 3 GO:0006206 pyrimidine nucleobase metabolic process 3/380 16/18722 0.00381681264880371 0.024448525181767 CDA/TYMP/MAPK1 3 GO:0009299 mRNA transcription 3/380 16/18722 0.00381681264880371 0.024448525181767 C5AR1/STAT3/DDX5 3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 3/380 16/18722 0.00381681264880371 0.024448525181767 PRKCB/IL1B/HIF1A 3 GO:0045342 MHC class II biosynthetic process 3/380 16/18722 0.00381681264880371 0.024448525181767 SLC11A1/SPI1/TAF7 3 GO:0051014 actin filament severing 3/380 16/18722 0.00381681264880371 0.024448525181767 GMFG/FMNL1/MYH9 3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis 3/380 16/18722 0.00381681264880371 0.024448525181767 IL1B/TNFRSF1B/NRDC 3 GO:0071361 cellular response to ethanol 3/380 16/18722 0.00381681264880371 0.024448525181767 SOD2/SPI1/PTEN 3 GO:0072109 glomerular mesangium development 3/380 16/18722 0.00381681264880371 0.024448525181767 IL6R/CFLAR/EGR1 3 GO:0097284 hepatocyte apoptotic process 3/380 16/18722 0.00381681264880371 0.024448525181767 CFLAR/STK4/BID 3 GO:0006026 aminoglycan catabolic process 4/380 32/18722 0.00383325164597245 0.024448525181767 PGLYRP1/IDS/CD44/CTBS 4 GO:0090022 regulation of neutrophil chemotaxis 4/380 32/18722 0.00383325164597245 0.024448525181767 CXCL8/CXCR2/C5AR1/RAC2 4 GO:1900745 positive regulation of p38MAPK cascade 4/380 32/18722 0.00383325164597245 0.024448525181767 NCF1/SPI1/IL1B/PJA2 4 GO:1901532 regulation of hematopoietic progenitor cell differentiation 4/380 32/18722 0.00383325164597245 0.024448525181767 OSM/SPI1/SOS2/NFE2L2 4 GO:1903955 positive regulation of protein targeting to mitochondrion 4/380 32/18722 0.00383325164597245 0.024448525181767 RAC2/UBE2D3/NPEPPS/SH3GLB1 4 GO:0051962 positive regulation of nervous system development 13/380 272/18722 0.00386990686619441 0.024645196358396 LYN/PLXNC1/IL1B/TSPO/CXCR4/TNFRSF1B/ACTR2/NUMB/NIN/HIF1A/DICER1/MME/PAK1 13 GO:0002437 inflammatory response to antigenic stimulus 6/380 74/18722 0.00390133889047448 0.0248080633651042 CXCR2/LYN/HCK/HLA-E/FGR/KDM6B 6 GO:0018209 peptidyl-serine modification 15/380 338/18722 0.00399590144576531 0.0253712782950766 PTGS2/LRRK2/OSM/RASSF2/PRKCB/ARRB2/PTEN/STK4/HCLS1/CD44/TGFBR2/RICTOR/PAK2/PAK1/MAPK1 15 GO:0070585 protein localization to mitochondrion 8/380 125/18722 0.00401270553884048 0.0254398322709423 LRRK2/RAC2/TSPO/BNIP3L/UBE2D3/BID/NPEPPS/SH3GLB1 8 GO:0033209 tumor necrosis factor-mediated signaling pathway 7/380 99/18722 0.00404359396196889 0.0255591349685646 TMSB4X/LAPTM5/TNFRSF1B/TNFSF13B/PYCARD/CARD16/HSPA1A 7 GO:0042100 B cell proliferation 7/380 99/18722 0.00404359396196889 0.0255591349685646 MNDA/PTPRC/LYN/TYROBP/BCL6/PELI1/TNFSF13B 7 GO:0009914 hormone transport 14/380 306/18722 0.00408884496398599 0.0258066444448296 LYN/FFAR2/OSM/HCAR2/ALOX5/MIDN/IL1B/GLUL/RAB11FIP1/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 14 GO:0043523 regulation of neuron apoptotic process 11/380 212/18722 0.0041501495893904 0.0261545885581374 SOD2/C5AR1/TYROBP/CORO1A/MCL1/CEBPB/ARRB2/BTG2/NQO2/HIF1A/CPEB4 11 GO:0002292 T cell differentiation involved in immune response 6/380 75/18722 0.00416973802683562 0.0262000601537817 FCER1G/BCL6/IL6R/FGL2/NFKBIZ/STAT3 6 GO:0033077 T cell differentiation in thymus 6/380 75/18722 0.00416973802683562 0.0262000601537817 PTPRC/B2M/IL1B/ZFP36L1/ZFP36L2/SOS2 6 GO:0032874 positive regulation of stress-activated MAPK cascade 8/380 126/18722 0.00421101872405001 0.0264202434020027 NCF1/SPI1/RASSF2/IL1B/SDCBP/CLEC7A/PYCARD/PJA2 8 GO:0006482 protein demethylation 4/380 33/18722 0.00429319536926971 0.026777146375342 KDM6B/JMJD1C/UBE2B/KDM5A 4 GO:0008214 protein dealkylation 4/380 33/18722 0.00429319536926971 0.026777146375342 KDM6B/JMJD1C/UBE2B/KDM5A 4 GO:0045920 negative regulation of exocytosis 4/380 33/18722 0.00429319536926971 0.026777146375342 SPI1/STXBP3/VPS4B/RAB7A 4 GO:1902992 negative regulation of amyloid precursor protein catabolic process 4/380 33/18722 0.00429319536926971 0.026777146375342 SORL1/RTN3/PICALM/FLOT2 4 GO:0002440 production of molecular mediator of immune response 14/380 308/18722 0.00432910568688679 0.0269373624928469 PTPRC/FFAR2/TREM1/LAPTM5/BCL6/B2M/HLA-E/IL1B/IRAK3/HLA-A/CLEC7A/TNFRSF1B/CD55/NBN 14 GO:0007566 embryo implantation 5/380 53/18722 0.00433160421667739 0.0269373624928469 PTGS2/ARHGDIB/IL1B/VMP1/TGFBR2 5 GO:0014855 striated muscle cell proliferation 6/380 76/18722 0.00445154077289552 0.0275017415078358 CFLAR/PTEN/STAT3/PRKAR1A/TGFBR2/MAPK1 6 GO:0140029 exocytic process 6/380 76/18722 0.00445154077289552 0.0275017415078358 LYN/PLEK/STX3/RALB/RAB8B/STXBP3 6 GO:0070372 regulation of ERK1 and ERK2 cascade 14/380 309/18722 0.00445346246478417 0.0275017415078358 PTPRC/C5AR1/LYN/FPR2/DUSP1/IL1B/ARRB2/CFLAR/PTEN/PYCARD/CD44/YWHAZ/NQO2/PTPN6 14 GO:0006606 protein import into nucleus 9/380 155/18722 0.0044548275500296 0.0275017415078358 PTGS2/LRRK2/TXNIP/HCLS1/STAT3/NUP214/KPNA4/PPP3CA/MAPK1 9 GO:1903364 positive regulation of cellular protein catabolic process 9/380 155/18722 0.0044548275500296 0.0275017415078358 LRRK2/LAPTM5/TRIB1/PTEN/AGTPBP1/FBXL5/MSN/HSPA1A/NFE2L2 9 GO:0050830 defense response to Gram-positive bacterium 7/380 101/18722 0.00451437628765828 0.0278287970571074 C5AR1/PGLYRP1/HLA-E/FGR/HLA-A/PYCARD/LYZ 7 GO:0020027 hemoglobin metabolic process 3/380 17/18722 0.00456560592407976 0.0279816803017044 SLC25A37/HIF1A/CAT 3 GO:0060263 regulation of respiratory burst 3/380 17/18722 0.00456560592407976 0.0279816803017044 NCF1/RAC2/CLEC7A 3 GO:0061158 3'-UTR-mediated mRNA destabilization 3/380 17/18722 0.00456560592407976 0.0279816803017044 ZFP36/ZFP36L1/ZFP36L2 3 GO:1903541 regulation of exosomal secretion 3/380 17/18722 0.00456560592407976 0.0279816803017044 SDCBP/VPS4B/RAB7A 3 GO:0051402 neuron apoptotic process 12/380 246/18722 0.0046114062937092 0.0282215399622232 SOD2/C5AR1/TYROBP/CORO1A/MCL1/CEBPB/ARRB2/BTG2/BID/NQO2/HIF1A/CPEB4 12 GO:0070228 regulation of lymphocyte apoptotic process 5/380 54/18722 0.00469575049230356 0.0286136738631735 LYN/BCL6/TSC22D3/PTEN/HIF1A 5 GO:1902743 regulation of lamellipodium organization 5/380 54/18722 0.00469575049230356 0.0286136738631735 RAC2/WAS/ACTR2/CD44/ACTR3 5 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 5/380 54/18722 0.00469575049230356 0.0286136738631735 SPI1/FOS/EGR1/STAT3/HIF1A 5 GO:1902106 negative regulation of leukocyte differentiation 7/380 102/18722 0.00476472681642645 0.0289892580791339 PGLYRP1/LYN/LILRB3/BCL6/TRIB1/FGL2/IRF1 7 GO:0009612 response to mechanical stimulus 11/380 216/18722 0.00477107742176065 0.0289892580791339 PTGS2/FOS/TXNIP/CNN2/CYBA/IL1B/BTG2/CXCR4/IRF1/MAP3K2/TGFBR2 11 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4/380 34/18722 0.00478895460439289 0.0290146248206064 FCER1G/CTSS/B2M/PYCARD 4 GO:0010661 positive regulation of muscle cell apoptotic process 4/380 34/18722 0.00478895460439289 0.0290146248206064 SOD2/CXCR2/PTEN/STK4 4 GO:0021537 telencephalon development 12/380 248/18722 0.00491439896115492 0.0297321137149872 BCL2A1/LRRK2/MBOAT7/KDM6B/BTG2/PTEN/CXCR4/AGTPBP1/NUMB/NCOA1/NIN/HIF1A 12 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 6/380 78/18722 0.00505692238393323 0.0304795730980214 S100A8/S100A9/LAPTM5/CFLAR/PYCARD/BID 6 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 12/380 249/18722 0.00507174485463781 0.0304795730980214 S100A12/LITAF/PELI1/PRKCB/S100A4/IL1B/CFLAR/CLEC7A/PYCARD/TNFSF10/CARD16/USP10 12 GO:0045926 negative regulation of growth 12/380 249/18722 0.00507174485463781 0.0304795730980214 RGS2/CDA/BCL6/CDKN2D/PTEN/STK4/TGFBR2/BTG1/DDX3X/HIF1A/HSPA1A/PAK1 12 GO:0046883 regulation of hormone secretion 12/380 249/18722 0.00507174485463781 0.0304795730980214 FFAR2/OSM/HCAR2/ALOX5/MIDN/IL1B/GLUL/RAB11FIP1/NADK/HIF1A/RAB8B/PPP3CA 12 GO:0006470 protein dephosphorylation 13/380 281/18722 0.00507404326549105 0.0304795730980214 PTPRC/LRRK2/DUSP1/PTPRE/PPP2R5A/LILRB2/PTEN/BOD1L1/CPPED1/SSH2/PTPN6/PPP3CA/PPP1R15A 13 GO:1902991 regulation of amyloid precursor protein catabolic process 5/380 55/18722 0.00508112836061466 0.0304795730980214 SORL1/LYN/RTN3/PICALM/FLOT2 5 GO:0072503 cellular divalent inorganic cation homeostasis 19/380 486/18722 0.00514629658726988 0.0308268260920622 S100A8/S100A9/PROK2/PTPRC/CXCR2/FPR1/C5AR1/LYN/FPR2/CXCR1/SLC11A1/CORO1A/PRKCB/CYBA/CXCR4/GPR65/CD55/GRINA/PTPN6 19 GO:1903532 positive regulation of secretion by cell 13/380 282/18722 0.00522457949187436 0.0312515454069038 CD177/HCAR2/FGR/ITGB2/IL1B/SDCBP/RAB27A/GLUL/NADK/HIF1A/RAB8B/VPS4B/RAB7A 13 GO:0051170 import into nucleus 9/380 159/18722 0.00525558067249246 0.031392643368132 PTGS2/LRRK2/TXNIP/HCLS1/STAT3/NUP214/KPNA4/PPP3CA/MAPK1 9 GO:0009746 response to hexose 11/380 219/18722 0.00528341298963297 0.0315046136486338 NAMPT/PTGS2/TXNIP/CYBA/PTEN/GLUL/EGR1/TGFBR2/NADK/HIF1A/PPP3CA 11 GO:0060419 heart growth 7/380 104/18722 0.00529664342805839 0.0315046136486338 RGS2/BASP1/PTEN/PRKAR1A/TGFBR2/PAK1/MAPK1 7 GO:1903076 regulation of protein localization to plasma membrane 7/380 104/18722 0.00529664342805839 0.0315046136486338 ACTB/PPP2R5A/STX3/NUMB/PICALM/RHOG/STX7 7 GO:0032814 regulation of natural killer cell activation 4/380 35/18722 0.00532175064715549 0.0315211384485364 PGLYRP1/TYROBP/HLA-E/FGR 4 GO:0035633 maintenance of blood-brain barrier 4/380 35/18722 0.00532175064715549 0.0315211384485364 PTGS2/ACTB/MBP/PECAM1 4 GO:0048821 erythrocyte development 4/380 35/18722 0.00532175064715549 0.0315211384485364 BCL6/KLF2/PTBP3/TMOD3 4 GO:0060420 regulation of heart growth 6/380 79/18722 0.00538128457497753 0.0316577047739102 RGS2/BASP1/PTEN/TGFBR2/PAK1/MAPK1 6 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 3/380 18/18722 0.00539713408424159 0.0316577047739102 PTPRC/CD55/PTPN6 3 GO:0030889 negative regulation of B cell proliferation 3/380 18/18722 0.00539713408424159 0.0316577047739102 MNDA/LYN/TYROBP 3 GO:0031643 positive regulation of myelination 3/380 18/18722 0.00539713408424159 0.0316577047739102 ITGAX/TNFRSF1B/DICER1 3 GO:0050665 hydrogen peroxide biosynthetic process 3/380 18/18722 0.00539713408424159 0.0316577047739102 SOD2/CYBA/STAT3 3 GO:0071800 podosome assembly 3/380 18/18722 0.00539713408424159 0.0316577047739102 LCP1/HCK/MSN 3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 3/380 18/18722 0.00539713408424159 0.0316577047739102 ZFP36/ZFP36L1/ZFP36L2 3 GO:0010951 negative regulation of endopeptidase activity 12/380 252/18722 0.00556802292313103 0.0326149060573443 PTGS2/SORL1/SERPINA1/PLAUR/CDKN2D/ARRB2/IFI16/CARD16/PICALM/CD44/DDX3X/PAK2 12 GO:0045861 negative regulation of proteolysis 15/380 351/18722 0.00562879655433706 0.0329253500105213 PTGS2/SORL1/LRRK2/SERPINA1/PLAUR/CDKN2D/ARRB2/SDCBP/IFI16/CARD16/PICALM/CD44/DDX3X/PAK2/N4BP1 15 GO:0007204 positive regulation of cytosolic calcium ion concentration 14/380 319/18722 0.00586356833573929 0.0341861436737231 PROK2/PTPRC/CXCR2/FPR1/C5AR1/LYN/FPR2/CXCR1/CORO1A/CYBA/CXCR4/GPR65/CD55/PTPN6 14 GO:0046620 regulation of organ growth 7/380 106/18722 0.00587192078278947 0.0341861436737231 RGS2/BASP1/PTEN/STK4/TGFBR2/PAK1/MAPK1 7 GO:1903707 negative regulation of hemopoiesis 7/380 106/18722 0.00587192078278947 0.0341861436737231 PGLYRP1/LYN/LILRB3/BCL6/TRIB1/FGL2/IRF1 7 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4/380 36/18722 0.00589277092841035 0.0341861436737231 FCER1G/CTSS/B2M/PYCARD 4 GO:0060251 regulation of glial cell proliferation 4/380 36/18722 0.00589277092841035 0.0341861436737231 LYN/IL1B/TSPO/DICER1 4 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 4/380 36/18722 0.00589277092841035 0.0341861436737231 RAC2/UBE2D3/NPEPPS/SH3GLB1 4 GO:0051494 negative regulation of cytoskeleton organization 9/380 162/18722 0.00592604886667918 0.034332170930761 GMFG/TMSB4X/CORO1A/WAS/MYADM/SSH2/CAPZA1/PAK2/TMOD3 9 GO:0032872 regulation of stress-activated MAPK cascade 10/380 192/18722 0.00598275144662746 0.0346133229186712 NCF1/DUSP1/SPI1/RASSF2/IL1B/SDCBP/CLEC7A/PYCARD/PJA2/MAPK1 10 GO:0060968 regulation of gene silencing 6/380 81/18722 0.00607530871365166 0.0350530414200474 NEAT1/ZFP36/STAT3/ADAR/DDX5/PPP3CA 6 GO:0071260 cellular response to mechanical stimulus 6/380 81/18722 0.00607530871365166 0.0350530414200474 PTGS2/CNN2/CYBA/IL1B/IRF1/MAP3K2 6 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 7/380 107/18722 0.00617647483611564 0.0355882597699996 LRRK2/LAPTM5/TRIB1/PTEN/AGTPBP1/HSPA1A/NFE2L2 7 GO:0007565 female pregnancy 10/380 193/18722 0.00619936244314187 0.0356537274473758 NAMPT/PTGS2/RGS2/JUNB/FOS/ARHGDIB/IL1B/VMP1/TGFBR2/MAPK1 10 GO:0034599 cellular response to oxidative stress 13/380 288/18722 0.00620467464668619 0.0356537274473758 SOD2/LRRK2/NCF1/AIF1/FOS/KLF2/MCL1/ALOX5/KDM6B/HIF1A/HSPA1A/MAPK1/NFE2L2 13 GO:0048608 reproductive structure development 17/380 424/18722 0.0062168704888533 0.0356754017890159 PTGS2/JUNB/BASP1/CEBPB/ARRB2/PTEN/STK4/ZFP36L1/TNFSF10/NCOA1/PTPN6/HIF1A/MME/KDM5A/SF1/MAPK1/NCOA4 17 GO:0002902 regulation of B cell apoptotic process 3/380 19/18722 0.00631374783879659 0.0358909021440316 LYN/BCL6/PTEN 3 GO:0010829 negative regulation of glucose transmembrane transport 3/380 19/18722 0.00631374783879659 0.0358909021440316 PRKCB/IL1B/STXBP3 3 GO:0030220 platelet formation 3/380 19/18722 0.00631374783879659 0.0358909021440316 ACTN1/PTPN6/MYH9 3 GO:0036344 platelet morphogenesis 3/380 19/18722 0.00631374783879659 0.0358909021440316 ACTN1/PTPN6/MYH9 3 GO:0070262 peptidyl-serine dephosphorylation 3/380 19/18722 0.00631374783879659 0.0358909021440316 DUSP1/PPP3CA/PPP1R15A 3 GO:2000269 regulation of fibroblast apoptotic process 3/380 19/18722 0.00631374783879659 0.0358909021440316 STK17B/BID/BTG1 3 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation 3/380 19/18722 0.00631374783879659 0.0358909021440316 HLA-E/HLA-A/IRF1 3 GO:0050806 positive regulation of synaptic transmission 9/380 164/18722 0.00640841763552756 0.0363315243459963 PTGS2/TYROBP/ARRB2/LILRB2/PTEN/GLUL/STX3/MME/MAPK1 9 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 9/380 164/18722 0.00640841763552756 0.0363315243459963 LRRK2/LAPTM5/TRIB1/PTEN/SDCBP/AGTPBP1/HSPA1A/NFE2L2/N4BP1 9 GO:1901654 response to ketone 10/380 194/18722 0.00642203153282415 0.0363600314726073 DUSP1/FOS/KLF2/TXNIP/CYBA/CFLAR/TSPO/MSN/NCOA1/NCOA4 10 GO:1905897 regulation of response to endoplasmic reticulum stress 6/380 82/18722 0.00644575158770199 0.036445604771586 LRRK2/ALOX5/GRINA/HSPA1A/PPP1R15A/NFE2L2 6 GO:0033138 positive regulation of peptidyl-serine phosphorylation 7/380 108/18722 0.00649265614915399 0.0364780323362545 PTGS2/OSM/ARRB2/STK4/HCLS1/CD44/PAK1 7 GO:0006623 protein targeting to vacuole 4/380 37/18722 0.00650316751213039 0.0364780323362545 SORL1/LAPTM5/NCOA4/RAB7A 4 GO:0006904 vesicle docking involved in exocytosis 4/380 37/18722 0.00650316751213039 0.0364780323362545 PLEK/RALB/RAB8B/STXBP3 4 GO:0032570 response to progesterone 4/380 37/18722 0.00650316751213039 0.0364780323362545 FOS/TXNIP/TSPO/NCOA1 4 GO:0071985 multivesicular body sorting pathway 4/380 37/18722 0.00650316751213039 0.0364780323362545 LYST/RAB27A/VPS4B/TMEM50A 4 GO:0072529 pyrimidine-containing compound catabolic process 4/380 37/18722 0.00650316751213039 0.0364780323362545 CDA/APOBEC3A/TYMP/TET2 4 GO:0003158 endothelium development 8/380 136/18722 0.00663509438450337 0.037168815765042 ITGAX/KDM6B/IL1B/PECAM1/MYADM/CXCR4/MSN/BTG1 8 GO:0061458 reproductive system development 17/380 427/18722 0.00665183443214809 0.0372133670015154 PTGS2/JUNB/BASP1/CEBPB/ARRB2/PTEN/STK4/ZFP36L1/TNFSF10/NCOA1/PTPN6/HIF1A/MME/KDM5A/SF1/MAPK1/NCOA4 17 GO:0023061 signal release 18/380 463/18722 0.00674071550155243 0.0376608577164572 LRRK2/LYN/FFAR2/OSM/HCAR2/PRKCB/ALOX5/MIDN/IL1B/GLUL/STX3/MCTP2/RAB11FIP1/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 18 GO:0050886 endocrine process 6/380 83/18722 0.0068323338448693 0.038122442467749 HCAR2/CYBA/IL1B/RAB11FIP1/RAB8B/MME 6 GO:0035306 positive regulation of dephosphorylation 5/380 59/18722 0.00684776907717141 0.0381582921602907 PTPRC/PLEK/PPP2R5A/LILRB2/PPP1R15A 5 GO:1902904 negative regulation of supramolecular fiber organization 9/380 166/18722 0.00692042509848045 0.038440792231418 GMFG/TMSB4X/CORO1A/WAS/MYADM/SSH2/CAPZA1/PAK2/TMOD3 9 GO:0007266 Rho protein signal transduction 8/380 137/18722 0.00692569645161085 0.038440792231418 BCL6/WAS/ARHGDIB/GPR65/CDC42EP3/RHOG/CDC42SE1/CUL3 8 GO:0045471 response to ethanol 8/380 137/18722 0.00692569645161085 0.038440792231418 S100A8/SOD2/RGS2/SPI1/PTEN/ACTR2/STAT3/CAT 8 GO:0072538 T-helper 17 type immune response 4/380 38/18722 0.00715405575041405 0.0396044785660177 IL6R/CLEC7A/NFKBIZ/STAT3 4 GO:0097242 amyloid-beta clearance 4/380 38/18722 0.00715405575041405 0.0396044785660177 C5AR1/ITGB2/PICALM/MME 4 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 8/380 138/18722 0.00722581638141668 0.0399495200721928 LRRK2/LAPTM5/PELI1/RASSF5/PTEN/UBE2D1/DDX3X/CUL3 8 GO:0006970 response to osmotic stress 6/380 84/18722 0.00723544282710695 0.039950587187481 PTGS2/AQP9/TSC22D3/TSPO/ZFP36L1/DDX3X 6 GO:0060252 positive regulation of glial cell proliferation 3/380 20/18722 0.0073175484547831 0.040246516501307 LYN/IL1B/TSPO 3 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/380 20/18722 0.0073175484547831 0.040246516501307 SOD2/HIF1A/NFE2L2 3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 3/380 20/18722 0.0073175484547831 0.040246516501307 LRRK2/GRINA/HSPA1A 3 GO:0002712 regulation of B cell mediated immunity 5/380 60/18722 0.00734885830278957 0.0403140089537744 PTPRC/BCL6/HLA-E/CD55/PTPN6 5 GO:0002889 regulation of immunoglobulin mediated immune response 5/380 60/18722 0.00734885830278957 0.0403140089537744 PTPRC/BCL6/HLA-E/CD55/PTPN6 5 GO:0007179 transforming growth factor beta receptor signaling pathway 10/380 198/18722 0.00737552644317094 0.0404079618199598 LRG1/SPI1/FOS/ARRB2/SDCBP/ZYX/USP15/STAT3/TGFBR2/HSPA1A 10 GO:0010466 negative regulation of peptidase activity 12/380 262/18722 0.00750676415960822 0.041073832320337 PTGS2/SORL1/SERPINA1/PLAUR/CDKN2D/ARRB2/IFI16/CARD16/PICALM/CD44/DDX3X/PAK2 12 GO:0002347 response to tumor cell 4/380 39/18722 0.0078465130873668 0.0426690657380173 LAPTM5/SPI1/TXNIP/HLA-A 4 GO:0045923 positive regulation of fatty acid metabolic process 4/380 39/18722 0.0078465130873668 0.0426690657380173 PTGS2/ELOVL5/IL1B/LPGAT1 4 GO:2000249 regulation of actin cytoskeleton reorganization 4/380 39/18722 0.0078465130873668 0.0426690657380173 GMFG/HCK/ARHGDIB/HCLS1 4 GO:0030865 cortical cytoskeleton organization 5/380 61/18722 0.00787495135679231 0.0426690657380173 LCP1/RAC2/PLEK/FMNL1/RHOG 5 GO:0090342 regulation of cell aging 5/380 61/18722 0.00787495135679231 0.0426690657380173 NAMPT/BCL6/B2M/PTEN/YPEL3 5 GO:0032609 interferon-gamma production 7/380 112/18722 0.00787891603474133 0.0426690657380173 PGLYRP1/LAPTM5/SLC11A1/IL1B/HLA-A/CLEC7A/PYCARD 7 GO:0032649 regulation of interferon-gamma production 7/380 112/18722 0.00787891603474133 0.0426690657380173 PGLYRP1/LAPTM5/SLC11A1/IL1B/HLA-A/CLEC7A/PYCARD 7 GO:1901222 regulation of NIK/NF-kappaB signaling 7/380 112/18722 0.00787891603474133 0.0426690657380173 LITAF/TMSB4X/LAPTM5/SPI1/RASSF2/IL1B/DDX3X 7 GO:0002791 regulation of peptide secretion 10/380 200/18722 0.0078915454098488 0.0426828797071643 S100A8/FFAR2/ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/RAB8B/PPP3CA 10 GO:0019216 regulation of lipid metabolic process 14/380 331/18722 0.00800680204163885 0.0432510288856384 PTGS2/SORL1/LYN/FPR2/HCAR2/FGR/MBOAT7/ELOVL5/IL1B/PPP2R5A/TSPO/LPGAT1/EGR1/SF1 14 GO:0050673 epithelial cell proliferation 17/380 437/18722 0.0082829310692611 0.0446856217558226 PROK2/C5AR1/JAML/LRG1/B2M/ZFP36/ALOX5/CYBA/CEBPB/CFLAR/PTEN/ZFP36L1/GLUL/STAT3/RICTOR/HIF1A/MAPK1 17 GO:1901990 regulation of mitotic cell cycle phase transition 13/380 299/18722 0.00837817584833041 0.0451036057371402 AIF1/DUSP1/NABP1/PTEN/ZFP36L1/ZFP36L2/BID/DDX3X/PTPN6/CUL3/VPS4B/TMOD3/NBN 13 GO:0071498 cellular response to fluid shear stress 3/380 21/18722 0.00841039926622054 0.0451036057371402 PTGS2/KLF2/NFE2L2 3 GO:0072111 cell proliferation involved in kidney development 3/380 21/18722 0.00841039926622054 0.0451036057371402 IL6R/CFLAR/EGR1 3 GO:0010573 vascular endothelial growth factor production 5/380 62/18722 0.00842664928080036 0.0451036057371402 PTGS2/C5AR1/IL6R/IL1B/HIF1A 5 GO:0032623 interleukin-2 production 5/380 62/18722 0.00842664928080036 0.0451036057371402 PTPRC/LAPTM5/ZFP36/IL1B/CLEC7A 5 GO:0032663 regulation of interleukin-2 production 5/380 62/18722 0.00842664928080036 0.0451036057371402 PTPRC/LAPTM5/ZFP36/IL1B/CLEC7A 5 GO:0090087 regulation of peptide transport 10/380 202/18722 0.0084349600339587 0.0451036057371402 S100A8/FFAR2/ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/RAB8B/PPP3CA 10 GO:0071276 cellular response to cadmium ion 4/380 40/18722 0.00858157800413037 0.0458297387736344 NCF1/FOS/UBE2D3/MAPK1 4 GO:0038061 NIK/NF-kappaB signaling 8/380 143/18722 0.00887585969775879 0.0473416446095825 LITAF/TMSB4X/LAPTM5/SPI1/RASSF2/IL1B/DDX3X/DICER1 8 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 5/380 63/18722 0.00900454352767755 0.0479675997983829 LRRK2/CEBPB/GRINA/HSPA1A/PPP1R15A 5 GO:0046718 viral entry into host cell 8/380 144/18722 0.0092370943609511 0.049144591229432 IFITM2/IFITM1/CXCR4/FCN1/PLSCR1/CD55/HSPA1A/IFITM3 8 GO:0007265 Ras protein signal transduction 14/380 337/18722 0.00928975349409702 0.049362742845045 AIF1/RAC2/BCL6/DENND3/WAS/ARHGDIB/CYTH4/SDCBP/GPR65/CDC42EP3/RALB/RHOG/CDC42SE1/CUL3 14 GO:0032735 positive regulation of interleukin-12 production 4/380 41/18722 0.00936024909763986 0.049612834704011 LTB/LAPTM5/CLEC7A/IRF1 4 GO:0071470 cellular response to osmotic stress 4/380 41/18722 0.00936024909763986 0.049612834704011 PTGS2/TSPO/ZFP36L1/DDX3X 4 GO:0008286 insulin receptor signaling pathway 7/380 116/18722 0.0094722368878947 0.0501436540252925 SORL1/PRKCB/IL1B/PTPRE/OSBPL8/PHIP/PAK1 7 GO:0046330 positive regulation of JNK cascade 6/380 89/18722 0.00951230279520411 0.0501788251033222 NCF1/RASSF2/IL1B/SDCBP/PYCARD/PJA2 6 GO:1900407 regulation of cellular response to oxidative stress 6/380 89/18722 0.00951230279520411 0.0501788251033222 SOD2/LRRK2/MCL1/ALOX5/HIF1A/NFE2L2 6 GO:0001503 ossification 16/380 408/18722 0.00954170192629553 0.0501788251033222 PTGS2/SRGN/IFITM1/ALPL/JUNB/IL6R/RASSF2/FGR/ALOX5/CEBPB/SNX10/HIF1A/ADAR/DDX5/MAPK1/CAT 16 GO:0010310 regulation of hydrogen peroxide metabolic process 3/380 22/18722 0.00959393677376832 0.0501788251033222 SOD2/RAC2/STAT3 3 GO:0046628 positive regulation of insulin receptor signaling pathway 3/380 22/18722 0.00959393677376832 0.0501788251033222 SORL1/OSBPL8/PAK1 3 GO:0060965 negative regulation of gene silencing by miRNA 3/380 22/18722 0.00959393677376832 0.0501788251033222 NEAT1/STAT3/PPP3CA 3 GO:0017038 protein import 10/380 206/18722 0.00960765444550557 0.0501788251033222 PTGS2/LRRK2/TXNIP/HCLS1/STAT3/NUP214/KPNA4/RAB8B/PPP3CA/MAPK1 10 GO:0043524 negative regulation of neuron apoptotic process 8/380 145/18722 0.00960918343893729 0.0501788251033222 SOD2/C5AR1/CORO1A/CEBPB/ARRB2/BTG2/HIF1A/CPEB4 8 GO:0030837 negative regulation of actin filament polymerization 5/380 64/18722 0.00960921538578378 0.0501788251033222 TMSB4X/MYADM/SSH2/CAPZA1/TMOD3 5 GO:0045670 regulation of osteoclast differentiation 5/380 64/18722 0.00960921538578378 0.0501788251033222 LILRB3/TYROBP/FOS/RASSF2/CEBPB 5 GO:0046888 negative regulation of hormone secretion 5/380 64/18722 0.00960921538578378 0.0501788251033222 OSM/MIDN/IL1B/RAB11FIP1/PPP3CA 5 GO:1905475 regulation of protein localization to membrane 9/380 175/18722 0.00962217807165808 0.0501846356323546 ACTB/ITGB2/PPP2R5A/STX3/NUMB/PICALM/RHOG/STX7/PAK1 9 GO:0010975 regulation of neuron projection development 17/380 445/18722 0.00980695825549934 0.0510854467552764 S100A9/RGS2/LRRK2/LYN/PLXNC1/B2M/VIM/PREX1/CFLAR/PTEN/IQGAP1/ACTR2/NIN/PPP3CA/PAK2/PAK1/NFE2L2 17 GO:0050728 negative regulation of inflammatory response 9/380 176/18722 0.00996545625229237 0.0518473061774671 PTPRC/PGLYRP1/LYN/FPR2/ZFP36/HCK/FGR/ALOX5/TNFRSF1B 9 GO:0045580 regulation of T cell differentiation 8/380 146/18722 0.00999231765640392 0.0519232702759149 PTPRC/BCL6/FGL2/LILRB2/IRF1/NFKBIZ/SOS2/TGFBR2 8 GO:0097581 lamellipodium organization 6/380 90/18722 0.0100225846548477 0.0520167230554904 RAC2/WAS/ACTR2/ARPC5/CD44/ACTR3 6 GO:0010591 regulation of lamellipodium assembly 4/380 42/18722 0.0101834842859882 0.0525939706721466 RAC2/WAS/ACTR2/ACTR3 4 GO:0030890 positive regulation of B cell proliferation 4/380 42/18722 0.0101834842859882 0.0525939706721466 PTPRC/BCL6/PELI1/TNFSF13B 4 GO:0046596 regulation of viral entry into host cell 4/380 42/18722 0.0101834842859882 0.0525939706721466 IFITM2/IFITM1/FCN1/IFITM3 4 GO:0051602 response to electrical stimulus 4/380 42/18722 0.0101834842859882 0.0525939706721466 SOD2/AIF1/BTG2/PTEN 4 GO:0050851 antigen receptor-mediated signaling pathway 11/380 240/18722 0.0101961186299439 0.0525950820923418 MNDA/PTPRC/LYN/LAPTM5/NFAM1/PRKCB/HLA-A/LCP2/NFKBIZ/PTPN6/MAPK1 11 GO:0070936 protein K48-linked ubiquitination 5/380 65/18722 0.0102412354283324 0.052763542626506 PELI1/UBE2D1/UBE2D3/UBE2B/CUL3 5 GO:0045446 endothelial cell differentiation 7/380 118/18722 0.0103517667357016 0.0532682042839568 KDM6B/IL1B/PECAM1/MYADM/CXCR4/MSN/BTG1 7 GO:0048015 phosphatidylinositol-mediated signaling 9/380 178/18722 0.0106796165245047 0.0548885630840746 NCF1/OSM/FGR/PTEN/ZFP36L1/PIK3AP1/HCLS1/PTPN6/CAT 9 GO:0002790 peptide secretion 11/380 242/18722 0.0108032847487026 0.0553943164933872 S100A8/FFAR2/ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 11 GO:0006929 substrate-dependent cell migration 3/380 23/18722 0.0108695813473447 0.0553943164933872 PTPRC/SDCBP/STK4 3 GO:0035162 embryonic hemopoiesis 3/380 23/18722 0.0108695813473447 0.0553943164933872 STK4/TGFBR2/HIF1A 3 GO:0045932 negative regulation of muscle contraction 3/380 23/18722 0.0108695813473447 0.0553943164933872 PTGS2/RGS2/DOCK5 3 GO:0050765 negative regulation of phagocytosis 3/380 23/18722 0.0108695813473447 0.0553943164933872 CNN2/PTEN/PLSCR1 3 GO:0072576 liver morphogenesis 3/380 23/18722 0.0108695813473447 0.0553943164933872 CEBPB/CFLAR/CUL3 3 GO:2000737 negative regulation of stem cell differentiation 3/380 23/18722 0.0108695813473447 0.0553943164933872 ZFP36L2/STAT3/NFE2L2 3 GO:0045600 positive regulation of fat cell differentiation 5/380 66/18722 0.0109011629878578 0.0554884918913192 PTGS2/ZFP36/CEBPB/STK4/ZFP36L1 5 GO:0030900 forebrain development 15/380 379/18722 0.0109815207061075 0.0558304203965967 BCL2A1/LRRK2/TYROBP/B2M/MBOAT7/KDM6B/BTG2/PTEN/CXCR4/AGTPBP1/NUMB/ARPC5/NCOA1/NIN/HIF1A 15 GO:0002861 regulation of inflammatory response to antigenic stimulus 4/380 43/18722 0.0110522001335644 0.0559881190976617 LYN/HCK/HLA-E/FGR 4 GO:0006509 membrane protein ectodomain proteolysis 4/380 43/18722 0.0110522001335644 0.0559881190976617 IL1B/TNFRSF1B/MYH9/NRDC 4 GO:0034142 toll-like receptor 4 signaling pathway 4/380 43/18722 0.0110522001335644 0.0559881190976617 LYN/PELI1/LY96/PIK3AP1 4 GO:0051592 response to calcium ion 8/380 149/18722 0.0112098932482164 0.0567191133885264 ALOX5AP/JUNB/DUSP1/FOS/TXNIP/IQGAP1/CPNE3/PPP3CA 8 GO:0007033 vacuole organization 9/380 180/18722 0.0114315569595962 0.0577716512218257 LRRK2/LAPTM5/CORO1A/LYST/ATG16L2/VMP1/RALB/SH3GLB1/RAB7A 9 GO:0042130 negative regulation of T cell proliferation 5/380 67/18722 0.0115895456557489 0.0584306260144008 PELI1/CEBPB/LILRB2/PRKAR1A/PTPN6 5 GO:0072665 protein localization to vacuole 5/380 67/18722 0.0115895456557489 0.0584306260144008 SORL1/LAPTM5/SH3GLB1/NCOA4/RAB7A 5 GO:0033273 response to vitamin 6/380 93/18722 0.0116699123225739 0.058765848616053 SOD2/PTGS2/ALPL/CDKN2D/TSPO/CAT 6 GO:0038127 ERBB signaling pathway 7/380 121/18722 0.0117804508976216 0.0592520303461135 NCF1/PLAUR/RASSF2/IQGAP1/CPNE3/MAPK1/RAB7A 7 GO:0031295 T cell costimulation 4/380 44/18722 0.0119672712894105 0.0599779809593534 LYN/LILRB2/TNFSF13B/PTPN6 4 GO:0042269 regulation of natural killer cell mediated cytotoxicity 4/380 44/18722 0.0119672712894105 0.0599779809593534 HLA-B/HLA-E/ARRB2/HLA-A 4 GO:0060711 labyrinthine layer development 4/380 44/18722 0.0119672712894105 0.0599779809593534 JUNB/ZFP36L1/NCOA1/MAPK1 4 GO:0043087 regulation of GTPase activity 14/380 348/18722 0.0120581587654496 0.0603068110000714 LRRK2/PLXNC1/BCL6/ARHGAP9/ARHGAP15/PREX1/ARRB2/IQGAP1/GPR65/PYCARD/CCPG1/PICALM/RHOG/RICTOR 14 GO:0048017 inositol lipid-mediated signaling 9/380 182/18722 0.0122224454839238 0.0603068110000714 NCF1/OSM/FGR/PTEN/ZFP36L1/PIK3AP1/HCLS1/PTPN6/CAT 9 GO:0001779 natural killer cell differentiation 3/380 24/18722 0.0122385475440919 0.0603068110000714 PTPRC/PGLYRP1/NFIL3 3 GO:0001783 B cell apoptotic process 3/380 24/18722 0.0122385475440919 0.0603068110000714 LYN/BCL6/PTEN 3 GO:0002755 MyD88-dependent toll-like receptor signaling pathway 3/380 24/18722 0.0122385475440919 0.0603068110000714 TLR1/IRAK3/IRF1 3 GO:0006213 pyrimidine nucleoside metabolic process 3/380 24/18722 0.0122385475440919 0.0603068110000714 CDA/APOBEC3A/TYMP 3 GO:0010288 response to lead ion 3/380 24/18722 0.0122385475440919 0.0603068110000714 PTGS2/PLSCR1/CAT 3 GO:0033032 regulation of myeloid cell apoptotic process 3/380 24/18722 0.0122385475440919 0.0603068110000714 CXCR2/HCAR2/PTEN 3 GO:0043302 positive regulation of leukocyte degranulation 3/380 24/18722 0.0122385475440919 0.0603068110000714 CD177/FGR/ITGB2 3 GO:0050855 regulation of B cell receptor signaling pathway 3/380 24/18722 0.0122385475440919 0.0603068110000714 LYN/NFAM1/PRKCB 3 GO:0051043 regulation of membrane protein ectodomain proteolysis 3/380 24/18722 0.0122385475440919 0.0603068110000714 IL1B/TNFRSF1B/NRDC 3 GO:0072010 glomerular epithelium development 3/380 24/18722 0.0122385475440919 0.0603068110000714 BASP1/PECAM1/IQGAP1 3 GO:1903077 negative regulation of protein localization to plasma membrane 3/380 24/18722 0.0122385475440919 0.0603068110000714 PPP2R5A/NUMB/PICALM 3 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 3/380 24/18722 0.0122385475440919 0.0603068110000714 SOD2/CYBA/RAB27A 3 GO:0009314 response to radiation 17/380 456/18722 0.0122588596325813 0.0603068110000714 NAMPT/SOD2/PTGS2/PTPRC/DUSP1/FOS/CDKN2D/NABP1/CYBA/EGR1/IFI16/CARD16/UBE2B/HIF1A/MME/CAT/N4BP1 17 GO:0014706 striated muscle tissue development 15/380 384/18722 0.0122607235586922 0.0603068110000714 RGS2/FOS/KDM6B/ARRB2/CFLAR/BTG2/PTEN/EGR1/PRKAR1A/TGFBR2/DDX5/PPP3CA/MYL6/PAK1/MAPK1 15 GO:0031640 killing of cells of other organism 5/380 68/18722 0.0123069188067628 0.0603238439197229 S100A12/PGLYRP1/TREM1/CLEC7A/LYZ 5 GO:0034394 protein localization to cell surface 5/380 68/18722 0.0123069188067628 0.0603238439197229 CD177/TYROBP/FCN1/STX3/PICALM 5 GO:0042987 amyloid precursor protein catabolic process 5/380 68/18722 0.0123069188067628 0.0603238439197229 SORL1/LYN/RTN3/PICALM/FLOT2 5 GO:0007249 I-kappaB kinase/NF-kappaB signaling 12/380 281/18722 0.0126176262837916 0.061775314811396 S100A12/LITAF/PELI1/PRKCB/S100A4/IL1B/CFLAR/CLEC7A/PYCARD/TNFSF10/CARD16/USP10 12 GO:0031669 cellular response to nutrient levels 10/380 215/18722 0.0126987014466108 0.0621004626170862 NAMPT/LRRK2/GLUL/IFI16/RALB/NCOA1/CPEB4/SH3GLB1/MAPK1/NFE2L2 10 GO:0050852 T cell receptor signaling pathway 7/380 123/18722 0.0128087964076299 0.06256661221028 PTPRC/LAPTM5/HLA-A/LCP2/NFKBIZ/PTPN6/MAPK1 7 GO:0042982 amyloid precursor protein metabolic process 6/380 95/18722 0.0128687945660579 0.0627872638102018 SORL1/LYN/ITM2B/RTN3/PICALM/FLOT2 6 GO:0002920 regulation of humoral immune response 4/380 45/18722 0.0129295300325113 0.0627942198253271 PTPRC/IL1B/CD55/PTPN6 4 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 4/380 45/18722 0.0129295300325113 0.0627942198253271 SOD2/MCL1/HIF1A/NFE2L2 4 GO:0035307 positive regulation of protein dephosphorylation 4/380 45/18722 0.0129295300325113 0.0627942198253271 PTPRC/PPP2R5A/LILRB2/PPP1R15A 4 GO:0071354 cellular response to interleukin-6 4/380 45/18722 0.0129295300325113 0.0627942198253271 SPI1/IL6R/JAK1/STAT3 4 GO:0050805 negative regulation of synaptic transmission 5/380 69/18722 0.0130538051483837 0.0633251601413572 PTGS2/LRRK2/IL1B/LILRB2/PTEN 5 GO:0010506 regulation of autophagy 13/380 317/18722 0.0131815874106666 0.0638718795013419 NAMPT/LRRK2/MCL1/TSPO/PYCARD/IFI16/RALB/BNIP3L/STAT3/BID/HIF1A/USP10/SH3GLB1 13 GO:0055074 calcium ion homeostasis 17/380 460/18722 0.0132617547904333 0.0641868931856972 PROK2/PTPRC/CXCR2/FPR1/C5AR1/LYN/FPR2/CXCR1/CORO1A/PRKCB/CYBA/SNX10/CXCR4/GPR65/CD55/GRINA/PTPN6 17 GO:0044772 mitotic cell cycle phase transition 16/380 424/18722 0.013372311029166 0.0646481018362076 AIF1/DUSP1/CDKN2D/NABP1/PTEN/ZFP36L1/ZFP36L2/BID/DDX3X/PTPN6/CUL3/PPP3CA/BACH1/VPS4B/TMOD3/NBN 16 GO:0043433 negative regulation of DNA-binding transcription factor activity 9/380 185/18722 0.0134843509455026 0.065024016602686 TMSB4X/SPI1/PELI1/TRIB1/IRAK3/ARRB2/EGLN1/PYCARD/CAT 9 GO:0055017 cardiac muscle tissue growth 6/380 96/18722 0.0134994899438628 0.065024016602686 RGS2/PTEN/PRKAR1A/TGFBR2/PAK1/MAPK1 6 GO:0031346 positive regulation of cell projection organization 14/380 353/18722 0.0135114839693893 0.065024016602686 S100A9/RGS2/LYN/PLXNC1/RAC2/CFLAR/IQGAP1/ACTR2/CDC42EP3/ACTR3/NIN/RAB8B/PAK1/NFE2L2 14 GO:0051480 regulation of cytosolic calcium ion concentration 14/380 353/18722 0.0135114839693893 0.065024016602686 PROK2/PTPRC/CXCR2/FPR1/C5AR1/LYN/FPR2/CXCR1/CORO1A/CYBA/CXCR4/GPR65/CD55/PTPN6 14 GO:0072659 protein localization to plasma membrane 12/380 284/18722 0.0136229866440573 0.0652726118307134 ACTB/PPP2R5A/MYADM/FAM126B/STX3/NUMB/PICALM/RHOG/RAB8B/STX7/FLOT2/RAB7A 12 GO:0031579 membrane raft organization 3/380 25/18722 0.01370185405372 0.0652726118307134 PTPRC/MYADM/FLOT2 3 GO:0032753 positive regulation of interleukin-4 production 3/380 25/18722 0.01370185405372 0.0652726118307134 FCER1G/HLA-E/CEBPB 3 GO:0035902 response to immobilization stress 3/380 25/18722 0.01370185405372 0.0652726118307134 SOD2/FOS/ACTR2 3 GO:0042832 defense response to protozoan 3/380 25/18722 0.01370185405372 0.0652726118307134 SLC11A1/LYST/CLEC7A 3 GO:0050995 negative regulation of lipid catabolic process 3/380 25/18722 0.01370185405372 0.0652726118307134 SORL1/HCAR2/IL1B 3 GO:1900078 positive regulation of cellular response to insulin stimulus 3/380 25/18722 0.01370185405372 0.0652726118307134 SORL1/OSBPL8/PAK1 3 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 3/380 25/18722 0.01370185405372 0.0652726118307134 STAT3/DDX5/PPP3CA 3 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 3/380 25/18722 0.01370185405372 0.0652726118307134 IQGAP1/PAK1/DOCK5 3 GO:1904375 regulation of protein localization to cell periphery 7/380 125/18722 0.0139001862502124 0.0658871748467332 ACTB/PPP2R5A/STX3/NUMB/PICALM/RHOG/STX7 7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 9/380 186/18722 0.0139257176826483 0.0658871748467332 S100A12/LITAF/PELI1/PRKCB/S100A4/CFLAR/CLEC7A/TNFSF10/CARD16 9 GO:1902115 regulation of organelle assembly 9/380 186/18722 0.0139257176826483 0.0658871748467332 LRRK2/LCP1/HCK/SDCBP/MSN/RALB/HSPA1A/VPS4B/SH3GLB1 9 GO:0031057 negative regulation of histone modification 4/380 46/18722 0.0139397659179865 0.0658871748467332 SPI1/UBE2B/TAF7/KDM5A 4 GO:0031294 lymphocyte costimulation 4/380 46/18722 0.0139397659179865 0.0658871748467332 LYN/LILRB2/TNFSF13B/PTPN6 4 GO:0061028 establishment of endothelial barrier 4/380 46/18722 0.0139397659179865 0.0658871748467332 IL1B/PECAM1/MYADM/MSN 4 GO:0061462 protein localization to lysosome 4/380 46/18722 0.0139397659179865 0.0658871748467332 SORL1/LAPTM5/NCOA4/RAB7A 4 GO:0034614 cellular response to reactive oxygen species 8/380 155/18722 0.0139688061846515 0.065950829645484 SOD2/LRRK2/NCF1/FOS/KLF2/KDM6B/MAPK1/NFE2L2 8 GO:0035335 peptidyl-tyrosine dephosphorylation 6/380 97/18722 0.0141514790666103 0.0664591793471065 PTPRC/DUSP1/PTPRE/PTEN/SSH2/PTPN6 6 GO:1990868 response to chemokine 6/380 97/18722 0.0141514790666103 0.0664591793471065 CXCL8/CXCR2/CXCR1/DUSP1/CXCR4/HIF1A 6 GO:1990869 cellular response to chemokine 6/380 97/18722 0.0141514790666103 0.0664591793471065 CXCL8/CXCR2/CXCR1/DUSP1/CXCR4/HIF1A 6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 6/380 97/18722 0.0141514790666103 0.0664591793471065 MCL1/IL1B/CFLAR/DDX3X/HSPA1A/PHIP 6 GO:0009895 negative regulation of catabolic process 13/380 320/18722 0.0141549420947084 0.0664591793471065 NAMPT/SORL1/LRRK2/HCAR2/ZFP36/SLC11A1/MCL1/IL1B/IRAK3/TSPO/SDCBP/STAT3/N4BP1 13 GO:0009267 cellular response to starvation 8/380 156/18722 0.0144727716370363 0.0678761770574185 LRRK2/GLUL/IFI16/RALB/CPEB4/SH3GLB1/MAPK1/NFE2L2 8 GO:0043550 regulation of lipid kinase activity 5/380 71/18722 0.0146381423657041 0.0685758107508374 LYN/FPR2/FGR/PPP2R5A/NRBF2 5 GO:0044706 multi-multicellular organism process 10/380 220/18722 0.0147110710100652 0.0688413101962722 NAMPT/PTGS2/RGS2/JUNB/FOS/ARHGDIB/IL1B/VMP1/TGFBR2/MAPK1 10 GO:1902882 regulation of response to oxidative stress 6/380 98/18722 0.014825098551576 0.0692983359447288 SOD2/LRRK2/MCL1/ALOX5/HIF1A/NFE2L2 6 GO:1990845 adaptive thermogenesis 8/380 157/18722 0.014989841159642 0.0698017610664475 G0S2/SORL1/ACSL1/CEBPB/KDM6B/CXCR4/TLE3/NRDC 8 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 4/380 47/18722 0.0149987255184102 0.0698017610664475 LAPTM5/PYCARD/CARD16/HSPA1A 4 GO:0045911 positive regulation of DNA recombination 4/380 47/18722 0.0149987255184102 0.0698017610664475 PTPRC/WAS/ACTR2/UBE2B 4 GO:0046677 response to antibiotic 4/380 47/18722 0.0149987255184102 0.0698017610664475 ALPL/KDM6B/ACTR2/JAK1 4 GO:0006839 mitochondrial transport 11/380 254/18722 0.015047278123578 0.0699508483571383 LRRK2/SLC25A37/RAC2/TSPO/BNIP3L/UBE2D3/STAT3/BID/NPEPPS/HSPA1A/SH3GLB1 11 GO:0001562 response to protozoan 3/380 26/18722 0.0152603332829143 0.0704771117264362 SLC11A1/LYST/CLEC7A 3 GO:0006027 glycosaminoglycan catabolic process 3/380 26/18722 0.0152603332829143 0.0704771117264362 PGLYRP1/IDS/CD44 3 GO:0046697 decidualization 3/380 26/18722 0.0152603332829143 0.0704771117264362 PTGS2/JUNB/MAPK1 3 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 3/380 26/18722 0.0152603332829143 0.0704771117264362 PTPRC/NFAM1/PRKCB 3 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 3/380 26/18722 0.0152603332829143 0.0704771117264362 STAT3/DDX5/PPP3CA 3 GO:1904376 negative regulation of protein localization to cell periphery 3/380 26/18722 0.0152603332829143 0.0704771117264362 PPP2R5A/NUMB/PICALM 3 GO:1903362 regulation of cellular protein catabolic process 11/380 255/18722 0.0154505416873417 0.0710881570083863 LRRK2/LAPTM5/TRIB1/PTEN/SDCBP/AGTPBP1/FBXL5/MSN/HSPA1A/NFE2L2/N4BP1 11 GO:0032729 positive regulation of interferon-gamma production 5/380 72/18722 0.0154765716084373 0.0710881570083863 SLC11A1/IL1B/HLA-A/CLEC7A/PYCARD 5 GO:0043903 regulation of biological process involved in symbiotic interaction 5/380 72/18722 0.0154765716084373 0.0710881570083863 IFITM2/CXCL8/IFITM1/FCN1/IFITM3 5 GO:0055021 regulation of cardiac muscle tissue growth 5/380 72/18722 0.0154765716084373 0.0710881570083863 RGS2/PTEN/TGFBR2/PAK1/MAPK1 5 GO:0070227 lymphocyte apoptotic process 5/380 72/18722 0.0154765716084373 0.0710881570083863 LYN/BCL6/TSC22D3/PTEN/HIF1A 5 GO:0000045 autophagosome assembly 6/380 99/18722 0.0155206794928409 0.0711364476755208 LRRK2/ATG16L2/VMP1/RALB/SH3GLB1/RAB7A 6 GO:0060291 long-term synaptic potentiation 6/380 99/18722 0.0155206794928409 0.0711364476755208 TYROBP/LILRB2/PTEN/STX3/MME/MAPK1 6 GO:0034504 protein localization to nucleus 12/380 290/18722 0.0158160339470183 0.0724117878547272 PTGS2/LRRK2/TXNIP/RASSF5/GLUL/OSBPL8/HCLS1/STAT3/NUP214/KPNA4/PPP3CA/MAPK1 12 GO:0034976 response to endoplasmic reticulum stress 11/380 256/18722 0.0158618782499985 0.072543255279421 CXCL8/LRRK2/ALOX5/CEBPB/NRBF2/BID/DDX3X/GRINA/HSPA1A/PPP1R15A/NFE2L2 11 GO:0002715 regulation of natural killer cell mediated immunity 4/380 48/18722 0.0161071122547169 0.0733479789233614 HLA-B/HLA-E/ARRB2/HLA-A 4 GO:0042149 cellular response to glucose starvation 4/380 48/18722 0.0161071122547169 0.0733479789233614 IFI16/CPEB4/SH3GLB1/NFE2L2 4 GO:0043303 mast cell degranulation 4/380 48/18722 0.0161071122547169 0.0733479789233614 LYN/ADGRE2/RAC2/FGR 4 GO:1905710 positive regulation of membrane permeability 4/380 48/18722 0.0161071122547169 0.0733479789233614 LAPTM5/BNIP3L/BID/HSPA1A 4 GO:0051865 protein autoubiquitination 5/380 73/18722 0.0163464700452678 0.0743580028374963 LRRK2/UBE2D3/UBE2B/CUL3/RNF213 5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2/380 10/18722 0.0166013812660222 0.0747150368348607 FGL2/APBB1IP 2 GO:0002765 immune response-inhibiting signal transduction 2/380 10/18722 0.0166013812660222 0.0747150368348607 LYN/LILRB2 2 GO:0010728 regulation of hydrogen peroxide biosynthetic process 2/380 10/18722 0.0166013812660222 0.0747150368348607 SOD2/STAT3 2 GO:0010968 regulation of microtubule nucleation 2/380 10/18722 0.0166013812660222 0.0747150368348607 HSPA1A/PAK1 2 GO:0050861 positive regulation of B cell receptor signaling pathway 2/380 10/18722 0.0166013812660222 0.0747150368348607 NFAM1/PRKCB 2 GO:0060439 trachea morphogenesis 2/380 10/18722 0.0166013812660222 0.0747150368348607 TGFBR2/MAPK1 2 GO:0071803 positive regulation of podosome assembly 2/380 10/18722 0.0166013812660222 0.0747150368348607 LCP1/MSN 2 GO:0097278 complement-dependent cytotoxicity 2/380 10/18722 0.0166013812660222 0.0747150368348607 RAB27A/CD55 2 GO:1901725 regulation of histone deacetylase activity 2/380 10/18722 0.0166013812660222 0.0747150368348607 LRRK2/KDM5A 2 GO:1902946 protein localization to early endosome 2/380 10/18722 0.0166013812660222 0.0747150368348607 SORL1/MSN 2 GO:0031589 cell-substrate adhesion 14/380 363/18722 0.0168216372178012 0.075625938022705 MEGF9/RAC2/BCL6/CORO1A/ITGB2/PREX1/MYADM/PTEN/IQGAP1/STK4/ZYX/CD44/ACTN1/DOCK5 14 GO:0032703 negative regulation of interleukin-2 production 3/380 27/18722 0.0169146405901588 0.0758026485707119 PTPRC/LAPTM5/ZFP36 3 GO:0036037 CD8-positive, alpha-beta T cell activation 3/380 27/18722 0.0169146405901588 0.0758026485707119 HLA-E/HLA-A/IRF1 3 GO:0060142 regulation of syncytium formation by plasma membrane fusion 3/380 27/18722 0.0169146405901588 0.0758026485707119 TYROBP/CFLAR/CD53 3 GO:0007040 lysosome organization 5/380 74/18722 0.0172482911434412 0.0764851025405248 LRRK2/LAPTM5/CORO1A/LYST/RAB7A 5 GO:0010822 positive regulation of mitochondrion organization 5/380 74/18722 0.0172482911434412 0.0764851025405248 PLAUR/PYCARD/TNFSF10/BID/HIF1A 5 GO:0080171 lytic vacuole organization 5/380 74/18722 0.0172482911434412 0.0764851025405248 LRRK2/LAPTM5/CORO1A/LYST/RAB7A 5 GO:1903201 regulation of oxidative stress-induced cell death 5/380 74/18722 0.0172482911434412 0.0764851025405248 SOD2/LRRK2/MCL1/HIF1A/NFE2L2 5 GO:0002279 mast cell activation involved in immune response 4/380 49/18722 0.0172655863113912 0.0764851025405248 LYN/ADGRE2/RAC2/FGR 4 GO:0042304 regulation of fatty acid biosynthetic process 4/380 49/18722 0.0172655863113912 0.0764851025405248 PTGS2/ELOVL5/IL1B/LPGAT1 4 GO:0060986 endocrine hormone secretion 4/380 49/18722 0.0172655863113912 0.0764851025405248 HCAR2/IL1B/RAB11FIP1/RAB8B 4 GO:0070741 response to interleukin-6 4/380 49/18722 0.0172655863113912 0.0764851025405248 SPI1/IL6R/JAK1/STAT3 4 GO:0072666 establishment of protein localization to vacuole 4/380 49/18722 0.0172655863113912 0.0764851025405248 SORL1/LAPTM5/NCOA4/RAB7A 4 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 4/380 49/18722 0.0172655863113912 0.0764851025405248 CFLAR/PTEN/STK4/DDX3X 4 GO:1904752 regulation of vascular associated smooth muscle cell migration 4/380 49/18722 0.0172655863113912 0.0764851025405248 IQGAP1/PAK1/NFE2L2/DOCK5 4 GO:0050853 B cell receptor signaling pathway 7/380 131/18722 0.0175720426651459 0.0777613382308182 MNDA/PTPRC/LYN/NFAM1/PRKCB/PTPN6/MAPK1 7 GO:0035710 CD4-positive, alpha-beta T cell activation 6/380 102/18722 0.0177424145960647 0.078433325484691 BCL6/IL6R/NFKBIZ/STAT3/TGFBR2/CD55 6 GO:0050804 modulation of chemical synaptic transmission 16/380 439/18722 0.0179681040528862 0.0793481967298991 PTGS2/SRGN/LRRK2/TYROBP/PRKCB/IL1B/ARRB2/LILRB2/PTEN/GLUL/STX3/MCTP2/STAT3/MME/PPP3CA/MAPK1 16 GO:0048662 negative regulation of smooth muscle cell proliferation 5/380 75/18722 0.0181824735089131 0.0802112242815071 SOD2/AIF1/TRIB1/PTEN/SF1 5 GO:0060537 muscle tissue development 15/380 403/18722 0.0182132330633512 0.0802633111584727 RGS2/FOS/KDM6B/ARRB2/CFLAR/BTG2/PTEN/EGR1/PRKAR1A/TGFBR2/DDX5/PPP3CA/MYL6/PAK1/MAPK1 15 GO:0007569 cell aging 7/380 132/18722 0.0182444891613266 0.0803174756738236 NAMPT/BCL6/B2M/SPI1/PTEN/YPEL3/MME 7 GO:0099177 regulation of trans-synaptic signaling 16/380 440/18722 0.0183129230050904 0.0805350248458544 PTGS2/SRGN/LRRK2/TYROBP/PRKCB/IL1B/ARRB2/LILRB2/PTEN/GLUL/STX3/MCTP2/STAT3/MME/PPP3CA/MAPK1 16 GO:0001961 positive regulation of cytokine-mediated signaling pathway 4/380 50/18722 0.0184747646308591 0.0808140683246818 LAPTM5/CXCR4/HIF1A/HSPA1A 4 GO:0002448 mast cell mediated immunity 4/380 50/18722 0.0184747646308591 0.0808140683246818 LYN/ADGRE2/RAC2/FGR 4 GO:0010665 regulation of cardiac muscle cell apoptotic process 4/380 50/18722 0.0184747646308591 0.0808140683246818 CXCR2/CFLAR/PTEN/NFE2L2 4 GO:0050873 brown fat cell differentiation 4/380 50/18722 0.0184747646308591 0.0808140683246818 PTGS2/RGS2/LRG1/CEBPB 4 GO:1904738 vascular associated smooth muscle cell migration 4/380 50/18722 0.0184747646308591 0.0808140683246818 IQGAP1/PAK1/NFE2L2/DOCK5 4 GO:0014013 regulation of gliogenesis 6/380 103/18722 0.0185290343195433 0.0808140683246818 LYN/IL1B/TSPO/CXCR4/TNFRSF1B/DICER1 6 GO:0019233 sensory perception of pain 6/380 103/18722 0.0185290343195433 0.0808140683246818 PTGS2/PROK2/ARRB2/CXCR4/MME/MAPK1 6 GO:1905037 autophagosome organization 6/380 103/18722 0.0185290343195433 0.0808140683246818 LRRK2/ATG16L2/VMP1/RALB/SH3GLB1/RAB7A 6 GO:0045589 regulation of regulatory T cell differentiation 3/380 28/18722 0.0186652631819981 0.0811574841640266 BCL6/LILRB2/IRF1 3 GO:0061082 myeloid leukocyte cytokine production 3/380 28/18722 0.0186652631819981 0.0811574841640266 LAPTM5/BCL6/IRAK3 3 GO:0090344 negative regulation of cell aging 3/380 28/18722 0.0186652631819981 0.0811574841640266 NAMPT/BCL6/PTEN 3 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 7/380 133/18722 0.018934822090091 0.0822097126271209 LRRK2/LAPTM5/TRIB1/PTEN/AGTPBP1/HSPA1A/NFE2L2 7 GO:0090276 regulation of peptide hormone secretion 9/380 196/18722 0.0189460872547981 0.0822097126271209 FFAR2/ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/RAB8B/PPP3CA 9 GO:0031100 animal organ regeneration 5/380 76/18722 0.0191494406029988 0.0829221686643149 C5AR1/LCP1/CEBPB/IGF2R/TGFBR2 5 GO:0032720 negative regulation of tumor necrosis factor production 5/380 76/18722 0.0191494406029988 0.0829221686643149 IRAK3/ARRB2/TSPO/PTPN6/DICER1 5 GO:0016197 endosomal transport 10/380 230/18722 0.0194373432220544 0.0840710377324481 SORL1/LRRK2/LYST/WAS/ACAP2/PICALM/CMTM6/VPS4B/TMEM50A/RAB7A 10 GO:0015833 peptide transport 11/380 264/18722 0.0194544550124673 0.0840710377324481 S100A8/FFAR2/ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 11 GO:0042594 response to starvation 9/380 197/18722 0.0195118704540405 0.0842332022149455 LRRK2/ZFP36/GLUL/IFI16/RALB/CPEB4/SH3GLB1/MAPK1/NFE2L2 9 GO:0042552 myelination 7/380 134/18722 0.0196432627841428 0.0847047044890159 ITGAX/MBP/PTEN/CXCR4/TNFRSF1B/TYMP/DICER1 7 GO:0014009 glial cell proliferation 4/380 51/18722 0.019735220982216 0.0847047044890159 LYN/IL1B/TSPO/DICER1 4 GO:1903307 positive regulation of regulated secretory pathway 4/380 51/18722 0.019735220982216 0.0847047044890159 CD177/FGR/ITGB2/RAB27A 4 GO:0001660 fever generation 2/380 11/18722 0.020021111970131 0.0847047044890159 PTGS2/IL1B 2 GO:0002357 defense response to tumor cell 2/380 11/18722 0.020021111970131 0.0847047044890159 LAPTM5/SPI1 2 GO:0002604 regulation of dendritic cell antigen processing and presentation 2/380 11/18722 0.020021111970131 0.0847047044890159 SLC11A1/FGL2 2 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 2/380 11/18722 0.020021111970131 0.0847047044890159 CD55/PTPN6 2 GO:0019372 lipoxygenase pathway 2/380 11/18722 0.020021111970131 0.0847047044890159 ALOX5AP/ALOX5 2 GO:0031652 positive regulation of heat generation 2/380 11/18722 0.020021111970131 0.0847047044890159 PTGS2/IL1B 2 GO:0034115 negative regulation of heterotypic cell-cell adhesion 2/380 11/18722 0.020021111970131 0.0847047044890159 MBP/MYADM 2 GO:0036490 regulation of translation in response to endoplasmic reticulum stress 2/380 11/18722 0.020021111970131 0.0847047044890159 DDX3X/PPP1R15A 2 GO:0042789 mRNA transcription by RNA polymerase II 2/380 11/18722 0.020021111970131 0.0847047044890159 C5AR1/STAT3 2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 2/380 11/18722 0.020021111970131 0.0847047044890159 HIF1A/NFE2L2 2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation 2/380 11/18722 0.020021111970131 0.0847047044890159 MBP/MYADM 2 GO:0090084 negative regulation of inclusion body assembly 2/380 11/18722 0.020021111970131 0.0847047044890159 SORL1/HSPA1A 2 GO:0090394 negative regulation of excitatory postsynaptic potential 2/380 11/18722 0.020021111970131 0.0847047044890159 LRRK2/PTEN 2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 2/380 11/18722 0.020021111970131 0.0847047044890159 LAPTM5/HSPA1A 2 GO:1905050 positive regulation of metallopeptidase activity 2/380 11/18722 0.020021111970131 0.0847047044890159 MBP/STAT3 2 GO:1905668 positive regulation of protein localization to endosome 2/380 11/18722 0.020021111970131 0.0847047044890159 SORL1/MSN 2 GO:2000786 positive regulation of autophagosome assembly 2/380 11/18722 0.020021111970131 0.0847047044890159 RALB/SH3GLB1 2 GO:0031099 regeneration 9/380 198/18722 0.0200897915974153 0.0849090129748231 C5AR1/LCP1/CEBPB/CFLAR/TSPO/PTEN/IGF2R/TGFBR2/PPP3CA 9 GO:0046700 heterocycle catabolic process 16/380 445/18722 0.0201138623278838 0.0849090129748231 CDA/ZFP36/SLC11A1/APOBEC3A/VIM/BTG2/TNFRSF1B/ZFP36L1/RNASET2/TYMP/ZFP36L2/DICER1/DDX5/HSPA1A/TET2/NFE2L2 16 GO:0010827 regulation of glucose transmembrane transport 5/380 77/18722 0.0201496004816286 0.0849090129748231 PRKCB/IL1B/OSBPL8/STXBP3/NFE2L2 5 GO:0032418 lysosome localization 5/380 77/18722 0.0201496004816286 0.0849090129748231 LYN/ADGRE2/RAC2/FGR/MYH9 5 GO:0000041 transition metal ion transport 6/380 105/18722 0.0201731473409579 0.0849237365695395 STEAP4/SLC25A37/FTH1/B2M/SLC11A1/FTL 6 GO:0060538 skeletal muscle organ development 8/380 166/18722 0.0202626194092932 0.0852156834144557 BASP1/FOS/CFLAR/BTG2/EGR1/DDX5/PPP3CA/MYL6 8 GO:0001773 myeloid dendritic cell activation 3/380 29/18722 0.0205125286814429 0.0856917781042231 SPI1/PYCARD/TGFBR2 3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 3/380 29/18722 0.0205125286814429 0.0856917781042231 LYN/HCK/FGR 3 GO:0010592 positive regulation of lamellipodium assembly 3/380 29/18722 0.0205125286814429 0.0856917781042231 RAC2/ACTR2/ACTR3 3 GO:0033028 myeloid cell apoptotic process 3/380 29/18722 0.0205125286814429 0.0856917781042231 CXCR2/HCAR2/PTEN 3 GO:0072539 T-helper 17 cell differentiation 3/380 29/18722 0.0205125286814429 0.0856917781042231 IL6R/NFKBIZ/STAT3 3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 3/380 29/18722 0.0205125286814429 0.0856917781042231 CDKN2D/CD44/BID 3 GO:0042886 amide transport 12/380 301/18722 0.0205174646983901 0.0856917781042231 S100A8/AQP9/FFAR2/ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 12 GO:0007254 JNK cascade 8/380 167/18722 0.0209204668399443 0.0872173225361588 LRRK2/NCF1/TRIB1/RASSF2/IL1B/SDCBP/PYCARD/PJA2 8 GO:0051056 regulation of small GTPase mediated signal transduction 12/380 302/18722 0.0209913853618711 0.0872173225361588 BCL6/ARHGAP9/DENND3/ARHGDIB/ARHGAP15/CYTH4/PREX1/ARHGAP26/GPR65/SOS2/CDC42SE1/CUL3 12 GO:0006906 vesicle fusion 6/380 106/18722 0.0210312209344481 0.0872173225361588 CORO1A/STX3/SAMD9/RAB8B/STX7/RAB7A 6 GO:0030038 contractile actin filament bundle assembly 6/380 106/18722 0.0210312209344481 0.0872173225361588 WAS/GPR65/ZYX/CUL3/PAK2/PAK1 6 GO:0043149 stress fiber assembly 6/380 106/18722 0.0210312209344481 0.0872173225361588 WAS/GPR65/ZYX/CUL3/PAK2/PAK1 6 GO:0046822 regulation of nucleocytoplasmic transport 6/380 106/18722 0.0210312209344481 0.0872173225361588 PTGS2/MX2/IL1B/HCLS1/NUP214/MAPK1 6 GO:0010662 regulation of striated muscle cell apoptotic process 4/380 52/18722 0.021047486099635 0.0872173225361588 CXCR2/CFLAR/PTEN/NFE2L2 4 GO:0043277 apoptotic cell clearance 4/380 52/18722 0.021047486099635 0.0872173225361588 TYROBP/RAC2/FCN1/RHOG 4 GO:0007272 ensheathment of neurons 7/380 136/18722 0.0211153357230018 0.0873275847528442 ITGAX/MBP/PTEN/CXCR4/TNFRSF1B/TYMP/DICER1 7 GO:0008366 axon ensheathment 7/380 136/18722 0.0211153357230018 0.0873275847528442 ITGAX/MBP/PTEN/CXCR4/TNFRSF1B/TYMP/DICER1 7 GO:0090559 regulation of membrane permeability 5/380 78/18722 0.0211833455568132 0.0874380783948383 LAPTM5/BNIP3L/STAT3/BID/HSPA1A 5 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 5/380 78/18722 0.0211833455568132 0.0874380783948383 IRAK3/ARRB2/TSPO/PTPN6/DICER1 5 GO:0006874 cellular calcium ion homeostasis 16/380 448/18722 0.0212575359601979 0.0876588751620623 PROK2/PTPRC/CXCR2/FPR1/C5AR1/LYN/FPR2/CXCR1/CORO1A/PRKCB/CYBA/CXCR4/GPR65/CD55/GRINA/PTPN6 16 GO:0016482 cytosolic transport 8/380 168/18722 0.0215933292260482 0.0889569545450525 SORL1/LRRK2/LAPTM5/CORO1A/MSN/ACTR2/MAPK1/RAB7A 8 GO:0000018 regulation of DNA recombination 6/380 107/18722 0.0219136810987054 0.0901889596239236 PTPRC/BCL6/SMCHD1/WAS/ACTR2/UBE2B 6 GO:0032272 negative regulation of protein polymerization 5/380 79/18722 0.0222510523799103 0.0910955533139035 TMSB4X/MYADM/SSH2/CAPZA1/TMOD3 5 GO:0031214 biomineral tissue development 8/380 169/18722 0.0222813693385737 0.0910955533139035 PTGS2/SRGN/ALPL/FGR/ALOX5/CEBPB/SNX10/HIF1A 8 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 4/380 53/18722 0.0224120478859989 0.0910955533139035 CXCL8/RGS2/PLEK/ARRB2 4 GO:0097479 synaptic vesicle localization 4/380 53/18722 0.0224120478859989 0.0910955533139035 LRRK2/PTEN/RAB27A/PICALM 4 GO:1903202 negative regulation of oxidative stress-induced cell death 4/380 53/18722 0.0224120478859989 0.0910955533139035 SOD2/LRRK2/HIF1A/NFE2L2 4 GO:1990090 cellular response to nerve growth factor stimulus 4/380 53/18722 0.0224120478859989 0.0910955533139035 CORO1A/PTEN/ACAP2/ARPC3 4 GO:2000772 regulation of cellular senescence 4/380 53/18722 0.0224120478859989 0.0910955533139035 NAMPT/BCL6/B2M/YPEL3 4 GO:0017145 stem cell division 3/380 30/18722 0.0224566133789174 0.0910955533139035 EVI2B/ZFP36L2/CUL3 3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 3/380 30/18722 0.0224566133789174 0.0910955533139035 FCER1G/CTSS/B2M 3 GO:0034390 smooth muscle cell apoptotic process 3/380 30/18722 0.0224566133789174 0.0910955533139035 SOD2/ARRB2/STK4 3 GO:0034391 regulation of smooth muscle cell apoptotic process 3/380 30/18722 0.0224566133789174 0.0910955533139035 SOD2/ARRB2/STK4 3 GO:0051125 regulation of actin nucleation 3/380 30/18722 0.0224566133789174 0.0910955533139035 GMFG/CORO1A/WAS 3 GO:0070229 negative regulation of lymphocyte apoptotic process 3/380 30/18722 0.0224566133789174 0.0910955533139035 BCL6/TSC22D3/HIF1A 3 GO:0070498 interleukin-1-mediated signaling pathway 3/380 30/18722 0.0224566133789174 0.0910955533139035 IL1B/IRAK3/EGR1 3 GO:2000637 positive regulation of gene silencing by miRNA 3/380 30/18722 0.0224566133789174 0.0910955533139035 ZFP36/STAT3/DDX5 3 GO:0030072 peptide hormone secretion 10/380 236/18722 0.0227598384466989 0.0922372400208322 FFAR2/ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 10 GO:0007259 receptor signaling pathway via JAK-STAT 8/380 170/18722 0.022984747808298 0.0930596624934435 PTPRC/LYN/OSM/IL6R/JAK1/HCLS1/STAT3/IFNAR1 8 GO:0051303 establishment of chromosome localization 5/380 80/18722 0.0233530814462641 0.0943593891187328 ACTR2/ACTR3/UBE2B/CUL3/VPS4B 5 GO:0045598 regulation of fat cell differentiation 7/380 139/18722 0.0234645856630172 0.0943593891187328 PTGS2/ZFP36/ALOX5/CEBPB/STK4/ZFP36L1/ZFP36L2 7 GO:0110148 biomineralization 8/380 171/18722 0.0237036230568217 0.0943593891187328 PTGS2/SRGN/ALPL/FGR/ALOX5/CEBPB/SNX10/HIF1A 8 GO:0006216 cytidine catabolic process 2/380 12/18722 0.0237068217290039 0.0943593891187328 CDA/APOBEC3A 2 GO:0009972 cytidine deamination 2/380 12/18722 0.0237068217290039 0.0943593891187328 CDA/APOBEC3A 2 GO:0032490 detection of molecule of bacterial origin 2/380 12/18722 0.0237068217290039 0.0943593891187328 TLR1/LY96 2 GO:0033127 regulation of histone phosphorylation 2/380 12/18722 0.0237068217290039 0.0943593891187328 IL1B/UBE2B 2 GO:0034154 toll-like receptor 7 signaling pathway 2/380 12/18722 0.0237068217290039 0.0943593891187328 PIK3AP1/DDX3X 2 GO:0034333 adherens junction assembly 2/380 12/18722 0.0237068217290039 0.0943593891187328 ACTB/PAK2 2 GO:0035739 CD4-positive, alpha-beta T cell proliferation 2/380 12/18722 0.0237068217290039 0.0943593891187328 TGFBR2/CD55 2 GO:0043380 regulation of memory T cell differentiation 2/380 12/18722 0.0237068217290039 0.0943593891187328 BCL6/FGL2 2 GO:0046087 cytidine metabolic process 2/380 12/18722 0.0237068217290039 0.0943593891187328 CDA/APOBEC3A 2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development 2/380 12/18722 0.0237068217290039 0.0943593891187328 RGS2/PAK1 2 GO:0070586 cell-cell adhesion involved in gastrulation 2/380 12/18722 0.0237068217290039 0.0943593891187328 MBP/MYADM 2 GO:0150065 regulation of deacetylase activity 2/380 12/18722 0.0237068217290039 0.0943593891187328 LRRK2/KDM5A 2 GO:1901503 ether biosynthetic process 2/380 12/18722 0.0237068217290039 0.0943593891187328 ALOX5/LPCAT2 2 GO:1905666 regulation of protein localization to endosome 2/380 12/18722 0.0237068217290039 0.0943593891187328 SORL1/MSN 2 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation 2/380 12/18722 0.0237068217290039 0.0943593891187328 TGFBR2/CD55 2 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4/380 54/18722 0.0238293516774945 0.0945804164519112 PTPRC/BCL6/CD55/PTPN6 4 GO:0010659 cardiac muscle cell apoptotic process 4/380 54/18722 0.0238293516774945 0.0945804164519112 CXCR2/CFLAR/PTEN/NFE2L2 4 GO:0030520 intracellular estrogen receptor signaling pathway 4/380 54/18722 0.0238293516774945 0.0945804164519112 TAF7/DDX5/PAK1/NCOA4 4 GO:0016311 dephosphorylation 15/380 417/18722 0.0238553662472073 0.094595015034572 PTPRC/LRRK2/ALPL/DUSP1/PLEK/PTPRE/PPP2R5A/LILRB2/PTEN/BOD1L1/CPPED1/SSH2/PTPN6/PPP3CA/PPP1R15A 15 GO:0031333 negative regulation of protein-containing complex assembly 7/380 140/18722 0.0242861232183797 0.096080782366043 SORL1/TMSB4X/MYADM/SSH2/CAPZA1/DDX3X/TMOD3 7 GO:0050768 negative regulation of neurogenesis 7/380 140/18722 0.0242861232183797 0.096080782366043 SORL1/B2M/IL1B/TSPO/PTEN/DICER1/PPP3CA 7 GO:0050678 regulation of epithelial cell proliferation 14/380 381/18722 0.0242981152099249 0.096080782366043 C5AR1/JAML/LRG1/B2M/ZFP36/ALOX5/CYBA/CFLAR/PTEN/ZFP36L1/GLUL/STAT3/RICTOR/HIF1A 14 GO:0002323 natural killer cell activation involved in immune response 3/380 31/18722 0.0244975501758424 0.0964192611474837 PGLYRP1/CORO1A/RAB27A 3 GO:0031063 regulation of histone deacetylation 3/380 31/18722 0.0244975501758424 0.0964192611474837 LRRK2/BCL6/KDM5A 3 GO:0032509 endosome transport via multivesicular body sorting pathway 3/380 31/18722 0.0244975501758424 0.0964192611474837 LYST/VPS4B/TMEM50A 3 GO:0045066 regulatory T cell differentiation 3/380 31/18722 0.0244975501758424 0.0964192611474837 BCL6/LILRB2/IRF1 3 GO:0060148 positive regulation of posttranscriptional gene silencing 3/380 31/18722 0.0244975501758424 0.0964192611474837 ZFP36/STAT3/DDX5 3 GO:0090174 organelle membrane fusion 6/380 110/18722 0.0247100677053985 0.097075265985494 CORO1A/STX3/SAMD9/RAB8B/STX7/RAB7A 6 GO:1904659 glucose transmembrane transport 6/380 110/18722 0.0247100677053985 0.097075265985494 SLC2A3/PRKCB/IL1B/OSBPL8/STXBP3/NFE2L2 6 GO:1901361 organic cyclic compound catabolic process 17/380 495/18722 0.0250269711654552 0.098229122229567 CDA/ZFP36/SLC11A1/APOBEC3A/VIM/BTG2/TNFRSF1B/ZFP36L1/HSD17B11/RNASET2/TYMP/ZFP36L2/DICER1/DDX5/HSPA1A/TET2/NFE2L2 17 GO:0000768 syncytium formation by plasma membrane fusion 4/380 55/18722 0.0252998005650929 0.0988419330195282 TYROBP/CFLAR/CD53/MYH9 4 GO:0008333 endosome to lysosome transport 4/380 55/18722 0.0252998005650929 0.0988419330195282 LYST/DENND3/VPS4B/RAB7A 4 GO:0043331 response to dsRNA 4/380 55/18722 0.0252998005650929 0.0988419330195282 PELI1/IRAK3/RALB/MAPK1 4 GO:0045620 negative regulation of lymphocyte differentiation 4/380 55/18722 0.0252998005650929 0.0988419330195282 PGLYRP1/BCL6/FGL2/IRF1 4 GO:0140253 cell-cell fusion 4/380 55/18722 0.0252998005650929 0.0988419330195282 TYROBP/CFLAR/CD53/MYH9 4 GO:0050000 chromosome localization 5/380 82/18722 0.0256614669839648 0.100070269500084 ACTR2/ACTR3/UBE2B/CUL3/VPS4B 5 GO:0072527 pyrimidine-containing compound metabolic process 5/380 82/18722 0.0256614669839648 0.100070269500084 CDA/APOBEC3A/TYMP/TET2/MAPK1 5 GO:0050679 positive regulation of epithelial cell proliferation 9/380 207/18722 0.0258589211410867 0.100747498649956 C5AR1/JAML/LRG1/CYBA/CFLAR/GLUL/STAT3/RICTOR/HIF1A 9 GO:0007009 plasma membrane organization 7/380 142/18722 0.0259880574857409 0.101157558319957 S100A9/PTPRC/PTEN/CXCR4/PLSCR1/MYH9/SH3GLB1 7 GO:0097345 mitochondrial outer membrane permeabilization 3/380 32/18722 0.0266352362306565 0.103351049132554 BNIP3L/BID/HSPA1A 3 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 3/380 32/18722 0.0266352362306565 0.103351049132554 LRRK2/GRINA/HSPA1A 3 GO:1905476 negative regulation of protein localization to membrane 3/380 32/18722 0.0266352362306565 0.103351049132554 PPP2R5A/NUMB/PICALM 3 GO:0046632 alpha-beta T cell differentiation 6/380 112/18722 0.0267010520149738 0.103351049132554 BCL6/IL6R/IRF1/NFKBIZ/STAT3/TGFBR2 6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 4/380 56/18722 0.0268237557690197 0.103351049132554 ZFP36/BTG2/ZFP36L1/ZFP36L2 4 GO:0010658 striated muscle cell apoptotic process 4/380 56/18722 0.0268237557690197 0.103351049132554 CXCR2/CFLAR/PTEN/NFE2L2 4 GO:0031529 ruffle organization 4/380 56/18722 0.0268237557690197 0.103351049132554 AIF1/PLEK/SNX10/RHOG 4 GO:0046456 icosanoid biosynthetic process 4/380 56/18722 0.0268237557690197 0.103351049132554 PTGS2/ALOX5AP/ALOX5/IL1B 4 GO:0071385 cellular response to glucocorticoid stimulus 4/380 56/18722 0.0268237557690197 0.103351049132554 ZFP36/CFLAR/ZFP36L1/ZFP36L2 4 GO:1990089 response to nerve growth factor 4/380 56/18722 0.0268237557690197 0.103351049132554 CORO1A/PTEN/ACAP2/ARPC3 4 GO:0031397 negative regulation of protein ubiquitination 5/380 83/18722 0.0268684626980094 0.103351049132554 IVNS1ABP/ARRB2/TSPO/HSPA1A/N4BP1 5 GO:0048678 response to axon injury 5/380 83/18722 0.0268684626980094 0.103351049132554 LYN/TYROBP/AIF1/TSPO/PTEN 5 GO:0062013 positive regulation of small molecule metabolic process 7/380 143/18722 0.0268688323718871 0.103351049132554 PTGS2/TMSB4X/ELOVL5/IL1B/LPGAT1/STAT3/HIF1A 7 GO:0006401 RNA catabolic process 11/380 278/18722 0.0271409866236876 0.104303156398654 ZFP36/SLC11A1/VIM/BTG2/TNFRSF1B/ZFP36L1/RNASET2/ZFP36L2/DICER1/DDX5/HSPA1A 11 GO:0001768 establishment of T cell polarity 2/380 13/18722 0.0276463639067208 0.104537813522288 MYH9/FLOT2 2 GO:0008298 intracellular mRNA localization 2/380 13/18722 0.0276463639067208 0.104537813522288 ZFP36/ZFP36L1 2 GO:0014842 regulation of skeletal muscle satellite cell proliferation 2/380 13/18722 0.0276463639067208 0.104537813522288 CFLAR/STAT3 2 GO:0016246 RNA interference 2/380 13/18722 0.0276463639067208 0.104537813522288 DICER1/ADAR 2 GO:0031053 primary miRNA processing 2/380 13/18722 0.0276463639067208 0.104537813522288 STAT3/DDX3X 2 GO:0031392 regulation of prostaglandin biosynthetic process 2/380 13/18722 0.0276463639067208 0.104537813522288 PTGS2/IL1B 2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 2/380 13/18722 0.0276463639067208 0.104537813522288 TRIB1/CARD16 2 GO:0032352 positive regulation of hormone metabolic process 2/380 13/18722 0.0276463639067208 0.104537813522288 EGR1/HIF1A 2 GO:0032494 response to peptidoglycan 2/380 13/18722 0.0276463639067208 0.104537813522288 C5AR1/IRAK3 2 GO:0034112 positive regulation of homotypic cell-cell adhesion 2/380 13/18722 0.0276463639067208 0.104537813522288 PLAUR/JAK1 2 GO:0042541 hemoglobin biosynthetic process 2/380 13/18722 0.0276463639067208 0.104537813522288 SLC25A37/HIF1A 2 GO:0043379 memory T cell differentiation 2/380 13/18722 0.0276463639067208 0.104537813522288 BCL6/FGL2 2 GO:0044090 positive regulation of vacuole organization 2/380 13/18722 0.0276463639067208 0.104537813522288 RALB/SH3GLB1 2 GO:0046689 response to mercury ion 2/380 13/18722 0.0276463639067208 0.104537813522288 AQP9/UBE2D3 2 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/380 13/18722 0.0276463639067208 0.104537813522288 ZFP36/BTG2 2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/380 13/18722 0.0276463639067208 0.104537813522288 PTEN/STK4 2 GO:1903651 positive regulation of cytoplasmic transport 2/380 13/18722 0.0276463639067208 0.104537813522288 SORL1/MSN 2 GO:2000318 positive regulation of T-helper 17 type immune response 2/380 13/18722 0.0276463639067208 0.104537813522288 CLEC7A/NFKBIZ 2 GO:0106106 cold-induced thermogenesis 7/380 144/18722 0.0277697240950735 0.104817095849052 G0S2/ACSL1/CEBPB/KDM6B/CXCR4/TLE3/NRDC 7 GO:0120161 regulation of cold-induced thermogenesis 7/380 144/18722 0.0277697240950735 0.104817095849052 G0S2/ACSL1/CEBPB/KDM6B/CXCR4/TLE3/NRDC 7 GO:0045445 myoblast differentiation 5/380 84/18722 0.0281110588923703 0.105916667623833 IFRD1/ZFP36L1/BTG1/DDX5/FLOT2 5 GO:0098586 cellular response to virus 5/380 84/18722 0.0281110588923703 0.105916667623833 SEC14L1/USP15/DDX3X/HIF1A/ADAR 5 GO:0071466 cellular response to xenobiotic stimulus 8/380 177/18722 0.0283508833476882 0.106537209441679 S100A12/ACSL1/RNF149/APOBEC3A/IL1B/CXCR4/NCOA1/NFE2L2 8 GO:0006949 syncytium formation 4/380 57/18722 0.0284015370624924 0.106537209441679 TYROBP/CFLAR/CD53/MYH9 4 GO:0033619 membrane protein proteolysis 4/380 57/18722 0.0284015370624924 0.106537209441679 IL1B/TNFRSF1B/MYH9/NRDC 4 GO:0051785 positive regulation of nuclear division 4/380 57/18722 0.0284015370624924 0.106537209441679 IL1B/UBE2B/CUL3/PHIP 4 GO:0060760 positive regulation of response to cytokine stimulus 4/380 57/18722 0.0284015370624924 0.106537209441679 LAPTM5/CXCR4/HIF1A/HSPA1A 4 GO:0051961 negative regulation of nervous system development 7/380 145/18722 0.02869091093995 0.106872447326598 SORL1/B2M/IL1B/TSPO/PTEN/DICER1/PPP3CA 7 GO:0008645 hexose transmembrane transport 6/380 114/18722 0.0287956568377117 0.106872447326598 SLC2A3/PRKCB/IL1B/OSBPL8/STXBP3/NFE2L2 6 GO:1901987 regulation of cell cycle phase transition 14/380 390/18722 0.028854692466171 0.106872447326598 AIF1/DUSP1/CDKN2D/NABP1/PTEN/ZFP36L1/ZFP36L2/BID/DDX3X/PTPN6/CUL3/VPS4B/TMOD3/NBN 14 GO:0010737 protein kinase A signaling 3/380 33/18722 0.0288694403167952 0.106872447326598 LRRK2/LCP1/PJA2 3 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 3/380 33/18722 0.0288694403167952 0.106872447326598 PRKCB/IL1B/HIF1A 3 GO:0031116 positive regulation of microtubule polymerization 3/380 33/18722 0.0288694403167952 0.106872447326598 NIN/HSPA1A/PAK1 3 GO:0032633 interleukin-4 production 3/380 33/18722 0.0288694403167952 0.106872447326598 FCER1G/HLA-E/CEBPB 3 GO:0032673 regulation of interleukin-4 production 3/380 33/18722 0.0288694403167952 0.106872447326598 FCER1G/HLA-E/CEBPB 3 GO:0034110 regulation of homotypic cell-cell adhesion 3/380 33/18722 0.0288694403167952 0.106872447326598 LYN/PLAUR/JAK1 3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 3/380 33/18722 0.0288694403167952 0.106872447326598 LYN/FPR2/FGR 3 GO:0045648 positive regulation of erythrocyte differentiation 3/380 33/18722 0.0288694403167952 0.106872447326598 STAT3/HIF1A/HSPA1A 3 GO:0071353 cellular response to interleukin-4 3/380 33/18722 0.0288694403167952 0.106872447326598 CORO1A/IL2RG/NFIL3 3 GO:1901099 negative regulation of signal transduction in absence of ligand 3/380 33/18722 0.0288694403167952 0.106872447326598 MCL1/IL1B/HSPA1A 3 GO:1903146 regulation of autophagy of mitochondrion 3/380 33/18722 0.0288694403167952 0.106872447326598 TSPO/BNIP3L/HIF1A 3 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 3/380 33/18722 0.0288694403167952 0.106872447326598 MCL1/IL1B/HSPA1A 3 GO:0035265 organ growth 8/380 178/18722 0.0291824723746615 0.107936917473093 RGS2/BASP1/PTEN/STK4/PRKAR1A/TGFBR2/PAK1/MAPK1 8 GO:0010507 negative regulation of autophagy 5/380 85/18722 0.029389533568435 0.108513229871249 NAMPT/LRRK2/MCL1/TSPO/STAT3 5 GO:0071277 cellular response to calcium ion 5/380 85/18722 0.029389533568435 0.108513229871249 ALOX5AP/JUNB/FOS/IQGAP1/CPNE3 5 GO:0009749 response to glucose 9/380 212/18722 0.0295276360749441 0.108928169666715 TXNIP/CYBA/PTEN/GLUL/EGR1/TGFBR2/NADK/HIF1A/PPP3CA 9 GO:0010043 response to zinc ion 4/380 58/18722 0.0300334232411695 0.110409329363153 S100A8/SOD2/TSPO/PTEN 4 GO:0010574 regulation of vascular endothelial growth factor production 4/380 58/18722 0.0300334232411695 0.110409329363153 PTGS2/C5AR1/IL1B/HIF1A 4 GO:2000736 regulation of stem cell differentiation 4/380 58/18722 0.0300334232411695 0.110409329363153 OSM/ZFP36L2/STAT3/NFE2L2 4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 4/380 58/18722 0.0300334232411695 0.110409329363153 S100A8/S100A9/MCL1/BID 4 GO:0035023 regulation of Rho protein signal transduction 5/380 86/18722 0.0307041479227395 0.112777160843713 BCL6/ARHGDIB/GPR65/CDC42SE1/CUL3 5 GO:0015749 monosaccharide transmembrane transport 6/380 116/18722 0.0309956570827407 0.113749226815777 SLC2A3/PRKCB/IL1B/OSBPL8/STXBP3/NFE2L2 6 GO:0000082 G1/S transition of mitotic cell cycle 9/380 214/18722 0.0310922998704684 0.114004482255741 AIF1/CDKN2D/PTEN/BID/DDX3X/PTPN6/CUL3/PPP3CA/BACH1 9 GO:0009112 nucleobase metabolic process 3/380 34/18722 0.0311998099018664 0.114004482255741 CDA/TYMP/MAPK1 3 GO:0010614 negative regulation of cardiac muscle hypertrophy 3/380 34/18722 0.0311998099018664 0.114004482255741 RGS2/TNFRSF1B/PAK1 3 GO:0010922 positive regulation of phosphatase activity 3/380 34/18722 0.0311998099018664 0.114004482255741 PTPRC/PLEK/PPP1R15A 3 GO:0032743 positive regulation of interleukin-2 production 3/380 34/18722 0.0311998099018664 0.114004482255741 PTPRC/IL1B/CLEC7A 3 GO:0002820 negative regulation of adaptive immune response 4/380 59/18722 0.0317196526349148 0.114036773376936 PTPRC/BCL6/CD55/PTPN6 4 GO:0048010 vascular endothelial growth factor receptor signaling pathway 4/380 59/18722 0.0317196526349148 0.114036773376936 PRKCB/IL1B/HIF1A/PAK2 4 GO:0097696 receptor signaling pathway via STAT 8/380 181/18722 0.03177783978072 0.114036773376936 PTPRC/LYN/OSM/IL6R/JAK1/HCLS1/STAT3/IFNAR1 8 GO:0001767 establishment of lymphocyte polarity 2/380 14/18722 0.0318279731125239 0.114036773376936 MYH9/FLOT2 2 GO:0002467 germinal center formation 2/380 14/18722 0.0318279731125239 0.114036773376936 BCL6/TNFSF13B 2 GO:0002475 antigen processing and presentation via MHC class Ib 2/380 14/18722 0.0318279731125239 0.114036773376936 B2M/HLA-E 2 GO:0006596 polyamine biosynthetic process 2/380 14/18722 0.0318279731125239 0.114036773376936 SAT1/OAZ1 2 GO:0031054 pre-miRNA processing 2/380 14/18722 0.0318279731125239 0.114036773376936 DICER1/ADAR 2 GO:0031650 regulation of heat generation 2/380 14/18722 0.0318279731125239 0.114036773376936 PTGS2/IL1B 2 GO:0034616 response to laminar fluid shear stress 2/380 14/18722 0.0318279731125239 0.114036773376936 KLF2/NFE2L2 2 GO:0036151 phosphatidylcholine acyl-chain remodeling 2/380 14/18722 0.0318279731125239 0.114036773376936 MBOAT7/LPCAT2 2 GO:0043249 erythrocyte maturation 2/380 14/18722 0.0318279731125239 0.114036773376936 KLF2/PTBP3 2 GO:0043951 negative regulation of cAMP-mediated signaling 2/380 14/18722 0.0318279731125239 0.114036773376936 RGS2/UBE2B 2 GO:0046131 pyrimidine ribonucleoside metabolic process 2/380 14/18722 0.0318279731125239 0.114036773376936 CDA/APOBEC3A 2 GO:0046133 pyrimidine ribonucleoside catabolic process 2/380 14/18722 0.0318279731125239 0.114036773376936 CDA/APOBEC3A 2 GO:0061043 regulation of vascular wound healing 2/380 14/18722 0.0318279731125239 0.114036773376936 ALOX5/CXCR4 2 GO:0072540 T-helper 17 cell lineage commitment 2/380 14/18722 0.0318279731125239 0.114036773376936 IL6R/STAT3 2 GO:0090239 regulation of histone H4 acetylation 2/380 14/18722 0.0318279731125239 0.114036773376936 SPI1/TAF7 2 GO:0090715 immunological memory formation process 2/380 14/18722 0.0318279731125239 0.114036773376936 BCL6/FGL2 2 GO:1902036 regulation of hematopoietic stem cell differentiation 2/380 14/18722 0.0318279731125239 0.114036773376936 OSM/NFE2L2 2 GO:1902916 positive regulation of protein polyubiquitination 2/380 14/18722 0.0318279731125239 0.114036773376936 UBE2D1/DDX3X 2 GO:1905049 negative regulation of metallopeptidase activity 2/380 14/18722 0.0318279731125239 0.114036773376936 SORL1/PICALM 2 GO:2001171 positive regulation of ATP biosynthetic process 2/380 14/18722 0.0318279731125239 0.114036773376936 TMSB4X/STAT3 2 GO:0009411 response to UV 7/380 149/18722 0.0325820169597097 0.116541251540853 PTGS2/CDKN2D/CARD16/UBE2B/MME/CAT/N4BP1 7 GO:0045834 positive regulation of lipid metabolic process 7/380 149/18722 0.0325820169597097 0.116541251540853 PTGS2/LYN/FPR2/FGR/ELOVL5/IL1B/LPGAT1 7 GO:0034219 carbohydrate transmembrane transport 6/380 118/18722 0.0333026954588741 0.118869443362167 SLC2A3/PRKCB/IL1B/OSBPL8/STXBP3/NFE2L2 6 GO:0050779 RNA destabilization 5/380 88/18722 0.0334427560932449 0.118869443362167 ZFP36/BTG2/TNFRSF1B/ZFP36L1/ZFP36L2 5 GO:0050829 defense response to Gram-negative bacterium 5/380 88/18722 0.0334427560932449 0.118869443362167 TREM1/SLC11A1/IL6R/PYCARD/LYZ 5 GO:0070098 chemokine-mediated signaling pathway 5/380 88/18722 0.0334427560932449 0.118869443362167 CXCL8/CXCR2/CXCR1/CXCR4/HIF1A 5 GO:0060038 cardiac muscle cell proliferation 4/380 60/18722 0.033460423658638 0.118869443362167 PTEN/PRKAR1A/TGFBR2/MAPK1 4 GO:1903670 regulation of sprouting angiogenesis 4/380 60/18722 0.033460423658638 0.118869443362167 KLF2/ALOX5/GLUL/JAK1 4 GO:0070374 positive regulation of ERK1 and ERK2 cascade 9/380 217/18722 0.0335461922693009 0.118869443362167 PTPRC/C5AR1/FPR2/ARRB2/CFLAR/PTEN/PYCARD/CD44/NQO2 9 GO:0001893 maternal placenta development 3/380 35/18722 0.0336258779569955 0.118869443362167 PTGS2/JUNB/MAPK1 3 GO:0006691 leukotriene metabolic process 3/380 35/18722 0.0336258779569955 0.118869443362167 CYP4F3/ALOX5AP/ALOX5 3 GO:0007020 microtubule nucleation 3/380 35/18722 0.0336258779569955 0.118869443362167 NIN/HSPA1A/PAK1 3 GO:0033280 response to vitamin D 3/380 35/18722 0.0336258779569955 0.118869443362167 PTGS2/ALPL/CDKN2D 3 GO:0034405 response to fluid shear stress 3/380 35/18722 0.0336258779569955 0.118869443362167 PTGS2/KLF2/NFE2L2 3 GO:0039694 viral RNA genome replication 3/380 35/18722 0.0336258779569955 0.118869443362167 CXCL8/APOBEC3A/ATG16L2 3 GO:0046627 negative regulation of insulin receptor signaling pathway 3/380 35/18722 0.0336258779569955 0.118869443362167 PRKCB/IL1B/PTPRE 3 GO:0030282 bone mineralization 6/380 119/18722 0.0344968304073678 0.121846602815015 PTGS2/SRGN/FGR/ALOX5/SNX10/HIF1A 6 GO:0051098 regulation of binding 13/380 363/18722 0.0349469730705991 0.123333692461656 SORL1/LRRK2/TMSB4X/B2M/ACTB/PLAUR/ARRB2/STK4/CCPG1/IFI16/CARD16/RALB/PPP3CA 13 GO:0071384 cellular response to corticosteroid stimulus 4/380 61/18722 0.0352558953991184 0.124172717684759 ZFP36/CFLAR/ZFP36L1/ZFP36L2 4 GO:0007369 gastrulation 8/380 185/18722 0.0354779402102049 0.124172717684759 DUSP1/MBP/ITGB2/KDM6B/MYADM/PRKAR1A/TGFBR2/CUL3 8 GO:0071774 response to fibroblast growth factor 6/380 120/18722 0.035718279518648 0.124172717684759 CXCL8/ZFP36/IER2/ZFP36L1/ZFP36L2/CD44 6 GO:0008643 carbohydrate transport 7/380 152/18722 0.0357214989406343 0.124172717684759 AQP9/SLC2A3/PRKCB/IL1B/OSBPL8/STXBP3/NFE2L2 7 GO:0031056 regulation of histone modification 7/380 152/18722 0.0357214989406343 0.124172717684759 LRRK2/BCL6/SPI1/IL1B/UBE2B/TAF7/KDM5A 7 GO:0051924 regulation of calcium ion transport 10/380 255/18722 0.0359806830456804 0.124172717684759 PTGS2/LYN/CORO1A/CYBA/ARRB2/TSPO/LILRB2/CXCR4/VMP1/PTPN6 10 GO:0002064 epithelial cell development 9/380 220/18722 0.0361308806735178 0.124172717684759 VIM/IL1B/PECAM1/MYADM/IQGAP1/CXCR4/MSN/HIF1A/FOSL2 9 GO:0014741 negative regulation of muscle hypertrophy 3/380 36/18722 0.0361470695050487 0.124172717684759 RGS2/TNFRSF1B/PAK1 3 GO:0030224 monocyte differentiation 3/380 36/18722 0.0361470695050487 0.124172717684759 ZFP36L1/IFI16/MYH9 3 GO:0070670 response to interleukin-4 3/380 36/18722 0.0361470695050487 0.124172717684759 CORO1A/IL2RG/NFIL3 3 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 3/380 36/18722 0.0361470695050487 0.124172717684759 CDKN2D/CD44/BID 3 GO:0002468 dendritic cell antigen processing and presentation 2/380 15/18722 0.036240254795363 0.124172717684759 SLC11A1/FGL2 2 GO:0002679 respiratory burst involved in defense response 2/380 15/18722 0.036240254795363 0.124172717684759 NCF1/HCK 2 GO:0014744 positive regulation of muscle adaptation 2/380 15/18722 0.036240254795363 0.124172717684759 AIF1/PPP3CA 2 GO:0014841 skeletal muscle satellite cell proliferation 2/380 15/18722 0.036240254795363 0.124172717684759 CFLAR/STAT3 2 GO:0014857 regulation of skeletal muscle cell proliferation 2/380 15/18722 0.036240254795363 0.124172717684759 CFLAR/STAT3 2 GO:0021542 dentate gyrus development 2/380 15/18722 0.036240254795363 0.124172717684759 BTG2/PTEN 2 GO:0032897 negative regulation of viral transcription 2/380 15/18722 0.036240254795363 0.124172717684759 ZFP36/IFITM3 2 GO:0042182 ketone catabolic process 2/380 15/18722 0.036240254795363 0.124172717684759 CYP4F3/NQO2 2 GO:0045346 regulation of MHC class II biosynthetic process 2/380 15/18722 0.036240254795363 0.124172717684759 SPI1/TAF7 2 GO:0045475 locomotor rhythm 2/380 15/18722 0.036240254795363 0.124172717684759 PTEN/EGR1 2 GO:0048308 organelle inheritance 2/380 15/18722 0.036240254795363 0.124172717684759 YWHAZ/MAPK1 2 GO:0048313 Golgi inheritance 2/380 15/18722 0.036240254795363 0.124172717684759 YWHAZ/MAPK1 2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 2/380 15/18722 0.036240254795363 0.124172717684759 ZFP36/BTG2 2 GO:0060253 negative regulation of glial cell proliferation 2/380 15/18722 0.036240254795363 0.124172717684759 TSPO/DICER1 2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport 2/380 15/18722 0.036240254795363 0.124172717684759 SORL1/LRRK2 2 GO:0070207 protein homotrimerization 2/380 15/18722 0.036240254795363 0.124172717684759 STEAP4/ALOX5AP 2 GO:0090594 inflammatory response to wounding 2/380 15/18722 0.036240254795363 0.124172717684759 ALOX5/HIF1A 2 GO:0098760 response to interleukin-7 2/380 15/18722 0.036240254795363 0.124172717684759 LSP1/IL2RG 2 GO:0098761 cellular response to interleukin-7 2/380 15/18722 0.036240254795363 0.124172717684759 LSP1/IL2RG 2 GO:1903729 regulation of plasma membrane organization 2/380 15/18722 0.036240254795363 0.124172717684759 MYH9/SH3GLB1 2 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA 2/380 15/18722 0.036240254795363 0.124172717684759 STAT3/PPP3CA 2 GO:1905168 positive regulation of double-strand break repair via homologous recombination 2/380 15/18722 0.036240254795363 0.124172717684759 WAS/ACTR2 2 GO:1905288 vascular associated smooth muscle cell apoptotic process 2/380 15/18722 0.036240254795363 0.124172717684759 SOD2/STK4 2 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 2/380 15/18722 0.036240254795363 0.124172717684759 SOD2/STK4 2 GO:2001279 regulation of unsaturated fatty acid biosynthetic process 2/380 15/18722 0.036240254795363 0.124172717684759 PTGS2/IL1B 2 GO:0035304 regulation of protein dephosphorylation 5/380 90/18722 0.0363286350831951 0.124174148165724 PTPRC/PPP2R5A/LILRB2/BOD1L1/PPP1R15A 5 GO:0045638 negative regulation of myeloid cell differentiation 5/380 90/18722 0.0363286350831951 0.124174148165724 LYN/LILRB3/ZFP36/TRIB1/ZFP36L1 5 GO:0099175 regulation of postsynapse organization 5/380 90/18722 0.0363286350831951 0.124174148165724 SRGN/LRRK2/LILRB2/PTEN/ACTR2 5 GO:0071478 cellular response to radiation 8/380 186/18722 0.0364465794249266 0.124476825697229 NAMPT/PTGS2/CYBA/EGR1/IFI16/CARD16/MME/N4BP1 8 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 9/380 221/18722 0.0370219784031544 0.126119347652208 LRRK2/LAPTM5/TRIB1/PTEN/SDCBP/AGTPBP1/HSPA1A/NFE2L2/N4BP1 9 GO:0032613 interleukin-10 production 4/380 62/18722 0.0371061882348644 0.126119347652208 TYROBP/CLEC7A/PYCARD/STAT3 4 GO:0032653 regulation of interleukin-10 production 4/380 62/18722 0.0371061882348644 0.126119347652208 TYROBP/CLEC7A/PYCARD/STAT3 4 GO:0046824 positive regulation of nucleocytoplasmic transport 4/380 62/18722 0.0371061882348644 0.126119347652208 PTGS2/IL1B/HCLS1/MAPK1 4 GO:0060135 maternal process involved in female pregnancy 4/380 62/18722 0.0371061882348644 0.126119347652208 PTGS2/RGS2/JUNB/MAPK1 4 GO:0070265 necrotic cell death 4/380 62/18722 0.0371061882348644 0.126119347652208 PELI1/PYGL/CFLAR/TSPO 4 GO:0001701 in utero embryonic development 13/380 367/18722 0.0376317131742522 0.127802971365644 JUNB/KLF2/CEBPB/STK4/ZFP36L1/TGFBR2/UBE2B/NCOA1/HIF1A/MYH9/CUL3/MAPK1/NBN 13 GO:0045582 positive regulation of T cell differentiation 5/380 91/18722 0.0378272744666462 0.128364188594749 PTPRC/BCL6/LILRB2/NFKBIZ/TGFBR2 5 GO:0016049 cell growth 16/380 482/18722 0.0379169071096595 0.12856533355437 S100A8/S100A9/RGS2/CDA/BCL6/CDKN2D/CYBA/SDCBP/IQGAP1/CXCR4/TGFBR2/BTG1/DDX3X/NIN/HSPA1A/PAK1 16 GO:0030308 negative regulation of cell growth 8/380 188/18722 0.0384370090437419 0.130224586640198 RGS2/CDA/BCL6/CDKN2D/BTG1/DDX3X/HSPA1A/PAK1 8 GO:0031112 positive regulation of microtubule polymerization or depolymerization 3/380 37/18722 0.0387627079161886 0.130596712828209 NIN/HSPA1A/PAK1 3 GO:0031646 positive regulation of nervous system process 3/380 37/18722 0.0387627079161886 0.130596712828209 ITGAX/TNFRSF1B/DICER1 3 GO:0043368 positive T cell selection 3/380 37/18722 0.0387627079161886 0.130596712828209 PTPRC/IL6R/STAT3 3 GO:0043403 skeletal muscle tissue regeneration 3/380 37/18722 0.0387627079161886 0.130596712828209 CFLAR/TGFBR2/PPP3CA 3 GO:0090218 positive regulation of lipid kinase activity 3/380 37/18722 0.0387627079161886 0.130596712828209 LYN/FPR2/FGR 3 GO:1900077 negative regulation of cellular response to insulin stimulus 3/380 37/18722 0.0387627079161886 0.130596712828209 PRKCB/IL1B/PTPRE 3 GO:1902745 positive regulation of lamellipodium organization 3/380 37/18722 0.0387627079161886 0.130596712828209 RAC2/ACTR2/ACTR3 3 GO:0016239 positive regulation of macroautophagy 4/380 63/18722 0.0390113844861991 0.131121597856392 RALB/BNIP3L/HIF1A/SH3GLB1 4 GO:0046902 regulation of mitochondrial membrane permeability 4/380 63/18722 0.0390113844861991 0.131121597856392 BNIP3L/STAT3/BID/HSPA1A 4 GO:2000242 negative regulation of reproductive process 4/380 63/18722 0.0390113844861991 0.131121597856392 DUSP1/ARHGDIB/PRKAR1A/MYH9 4 GO:0007519 skeletal muscle tissue development 7/380 155/18722 0.0390549363573847 0.131163882215324 FOS/CFLAR/BTG2/EGR1/DDX5/PPP3CA/MYL6 7 GO:0034655 nucleobase-containing compound catabolic process 14/380 407/18722 0.039127165338284 0.131302333761991 CDA/ZFP36/SLC11A1/APOBEC3A/VIM/BTG2/TNFRSF1B/ZFP36L1/RNASET2/TYMP/ZFP36L2/DICER1/DDX5/HSPA1A 14 GO:0045927 positive regulation of growth 10/380 259/18722 0.039329247831818 0.131875981447149 S100A8/S100A9/BASP1/CYBA/SDCBP/CXCR4/TGFBR2/DDX3X/PAK1/MAPK1 10 GO:1990778 protein localization to cell periphery 12/380 333/18722 0.0400568700827594 0.134209529114309 ACTB/PPP2R5A/MYADM/FAM126B/STX3/NUMB/PICALM/RHOG/RAB8B/STX7/FLOT2/RAB7A 12 GO:0001845 phagolysosome assembly 2/380 16/18722 0.0408721751020144 0.134925680955213 CORO1A/RAB7A 2 GO:0002827 positive regulation of T-helper 1 type immune response 2/380 16/18722 0.0408721751020144 0.134925680955213 SLC11A1/IL1B 2 GO:0002921 negative regulation of humoral immune response 2/380 16/18722 0.0408721751020144 0.134925680955213 CD55/PTPN6 2 GO:0017014 protein nitrosylation 2/380 16/18722 0.0408721751020144 0.134925680955213 S100A8/S100A9 2 GO:0018119 peptidyl-cysteine S-nitrosylation 2/380 16/18722 0.0408721751020144 0.134925680955213 S100A8/S100A9 2 GO:0034116 positive regulation of heterotypic cell-cell adhesion 2/380 16/18722 0.0408721751020144 0.134925680955213 IL1B/CD44 2 GO:0034393 positive regulation of smooth muscle cell apoptotic process 2/380 16/18722 0.0408721751020144 0.134925680955213 SOD2/STK4 2 GO:0035067 negative regulation of histone acetylation 2/380 16/18722 0.0408721751020144 0.134925680955213 SPI1/TAF7 2 GO:0044849 estrous cycle 2/380 16/18722 0.0408721751020144 0.134925680955213 EGR1/NCOA1 2 GO:0045651 positive regulation of macrophage differentiation 2/380 16/18722 0.0408721751020144 0.134925680955213 TRIB1/HCLS1 2 GO:0046135 pyrimidine nucleoside catabolic process 2/380 16/18722 0.0408721751020144 0.134925680955213 CDA/APOBEC3A 2 GO:0050965 detection of temperature stimulus involved in sensory perception of pain 2/380 16/18722 0.0408721751020144 0.134925680955213 ARRB2/CXCR4 2 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 2/380 16/18722 0.0408721751020144 0.134925680955213 NAMPT/LRRK2 2 GO:0071639 positive regulation of monocyte chemotactic protein-1 production 2/380 16/18722 0.0408721751020144 0.134925680955213 IL1B/CLEC7A 2 GO:0097202 activation of cysteine-type endopeptidase activity 2/380 16/18722 0.0408721751020144 0.134925680955213 PYCARD/IFI16 2 GO:0010508 positive regulation of autophagy 6/380 124/18722 0.0408804245258977 0.134925680955213 LRRK2/RALB/BNIP3L/BID/HIF1A/SH3GLB1 6 GO:0090398 cellular senescence 5/380 93/18722 0.0409367517075659 0.134925680955213 NAMPT/BCL6/B2M/SPI1/YPEL3 5 GO:1901992 positive regulation of mitotic cell cycle phase transition 5/380 93/18722 0.0409367517075659 0.134925680955213 AIF1/DDX3X/CUL3/VPS4B/TMOD3 5 GO:0001885 endothelial cell development 4/380 64/18722 0.0409715290928935 0.134925680955213 IL1B/PECAM1/MYADM/MSN 4 GO:0006940 regulation of smooth muscle contraction 4/380 64/18722 0.0409715290928935 0.134925680955213 PTGS2/RGS2/PROK2/DOCK5 4 GO:0032507 maintenance of protein location in cell 4/380 64/18722 0.0409715290928935 0.134925680955213 SRGN/SORL1/TMSB4X/TSPO 4 GO:0070542 response to fatty acid 4/380 64/18722 0.0409715290928935 0.134925680955213 PTGS2/ACSL1/FFAR2/CAT 4 GO:0001837 epithelial to mesenchymal transition 7/380 157/18722 0.0413867347161726 0.136150394388554 S100A4/IL1B/PTEN/SDCBP/TGFBR2/HIF1A/DDX5 7 GO:0048246 macrophage chemotaxis 3/380 38/18722 0.0414720209589693 0.136150394388554 C5AR1/CKLF/MAPK1 3 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 3/380 38/18722 0.0414720209589693 0.136150394388554 BNIP3L/BID/HSPA1A 3 GO:1903580 positive regulation of ATP metabolic process 3/380 38/18722 0.0414720209589693 0.136150394388554 TMSB4X/STAT3/HIF1A 3 GO:0031330 negative regulation of cellular catabolic process 10/380 262/18722 0.0419774348167862 0.137702894228574 NAMPT/SORL1/LRRK2/ZFP36/SLC11A1/MCL1/TSPO/SDCBP/STAT3/N4BP1 10 GO:1902414 protein localization to cell junction 5/380 94/18722 0.0425478584878415 0.139466084130038 ACTB/PECAM1/STX3/JAK1/PAK2 5 GO:0044270 cellular nitrogen compound catabolic process 15/380 451/18722 0.0429014967796742 0.140469428542936 CDA/ZFP36/SLC11A1/APOBEC3A/VIM/BTG2/TNFRSF1B/ZFP36L1/RNASET2/TYMP/ZFP36L2/DICER1/DDX5/HSPA1A/TET2 15 GO:0038034 signal transduction in absence of ligand 4/380 65/18722 0.0429866303167992 0.140469428542936 BCL2A1/MCL1/IL1B/HSPA1A 4 GO:0071677 positive regulation of mononuclear cell migration 4/380 65/18722 0.0429866303167992 0.140469428542936 FPR2/AIF1/SPI1/PYCARD 4 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 4/380 65/18722 0.0429866303167992 0.140469428542936 BCL2A1/MCL1/IL1B/HSPA1A 4 GO:0003012 muscle system process 15/380 452/18722 0.0435894682971439 0.142329528325678 PTGS2/RGS2/PROK2/AIF1/CYBA/IL1B/CFLAR/CXCR4/TNFRSF1B/TPM3/PPP3CA/MYL6/PAK1/TMOD3/DOCK5 15 GO:0036473 cell death in response to oxidative stress 5/380 95/18722 0.0441966953723851 0.144009993021701 SOD2/LRRK2/MCL1/HIF1A/NFE2L2 5 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 5/380 95/18722 0.0441966953723851 0.144009993021701 IVNS1ABP/ARRB2/TSPO/HSPA1A/N4BP1 5 GO:0016572 histone phosphorylation 3/380 39/18722 0.0442741466149361 0.144009993021701 PRKCB/IL1B/UBE2B 3 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 3/380 39/18722 0.0442741466149361 0.144009993021701 NFKBIZ/TGFBR2/CD55 3 GO:2000785 regulation of autophagosome assembly 3/380 39/18722 0.0442741466149361 0.144009993021701 LRRK2/RALB/SH3GLB1 3 GO:0001649 osteoblast differentiation 9/380 229/18722 0.0446957294829231 0.145269696362379 IFITM1/ALPL/JUNB/IL6R/RASSF2/CEBPB/ADAR/DDX5/CAT 9 GO:0030522 intracellular receptor signaling pathway 10/380 265/18722 0.0447450820586048 0.14531857555076 KLF2/SEC14L1/USP15/STAT3/NCOA1/TAF7/DDX5/HSPA1A/PAK1/NCOA4 10 GO:0032715 negative regulation of interleukin-6 production 4/380 66/18722 0.0450566604670534 0.145994611383299 KLF2/IRAK3/ARRB2/PTPN6 4 GO:0042093 T-helper cell differentiation 4/380 66/18722 0.0450566604670534 0.145994611383299 BCL6/IL6R/NFKBIZ/STAT3 4 GO:0042446 hormone biosynthetic process 4/380 66/18722 0.0450566604670534 0.145994611383299 TSPO/EGR1/HSD17B11/HIF1A 4 GO:0001780 neutrophil homeostasis 2/380 17/18722 0.0457130509924056 0.146773897613979 CXCR2/HCAR2 2 GO:0001829 trophectodermal cell differentiation 2/380 17/18722 0.0457130509924056 0.146773897613979 JUNB/CUL3 2 GO:0009251 glucan catabolic process 2/380 17/18722 0.0457130509924056 0.146773897613979 MGAM/PYGL 2 GO:0010934 macrophage cytokine production 2/380 17/18722 0.0457130509924056 0.146773897613979 LAPTM5/IRAK3 2 GO:0010935 regulation of macrophage cytokine production 2/380 17/18722 0.0457130509924056 0.146773897613979 LAPTM5/IRAK3 2 GO:0014856 skeletal muscle cell proliferation 2/380 17/18722 0.0457130509924056 0.146773897613979 CFLAR/STAT3 2 GO:0042953 lipoprotein transport 2/380 17/18722 0.0457130509924056 0.146773897613979 PRKCB/VMP1 2 GO:0045591 positive regulation of regulatory T cell differentiation 2/380 17/18722 0.0457130509924056 0.146773897613979 BCL6/LILRB2 2 GO:0060644 mammary gland epithelial cell differentiation 2/380 17/18722 0.0457130509924056 0.146773897613979 CEBPB/HIF1A 2 GO:0070206 protein trimerization 2/380 17/18722 0.0457130509924056 0.146773897613979 STEAP4/ALOX5AP 2 GO:0090083 regulation of inclusion body assembly 2/380 17/18722 0.0457130509924056 0.146773897613979 SORL1/HSPA1A 2 GO:0090713 immunological memory process 2/380 17/18722 0.0457130509924056 0.146773897613979 BCL6/FGL2 2 GO:1904035 regulation of epithelial cell apoptotic process 5/380 96/18722 0.0458833550113149 0.147209097327969 ZFP36/ARRB2/CFLAR/ZFP36L1/NFE2L2 5 GO:0030073 insulin secretion 8/380 195/18722 0.0459726331627835 0.147383876945033 ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/STXBP3/PPP3CA 8 GO:0035303 regulation of dephosphorylation 6/380 128/18722 0.0464913651405173 0.148934138706574 PTPRC/PLEK/PPP2R5A/LILRB2/BOD1L1/PPP1R15A 6 GO:0043393 regulation of protein binding 8/380 196/18722 0.0471226989461021 0.149785526532159 SORL1/LRRK2/B2M/ACTB/ARRB2/STK4/CARD16/RALB 8 GO:0010543 regulation of platelet activation 3/380 40/18722 0.0471681386644609 0.149785526532159 FCER1G/LYN/PLEK 3 GO:0030866 cortical actin cytoskeleton organization 3/380 40/18722 0.0471681386644609 0.149785526532159 LCP1/PLEK/FMNL1 3 GO:0034122 negative regulation of toll-like receptor signaling pathway 3/380 40/18722 0.0471681386644609 0.149785526532159 LYN/IRAK3/ARRB2 3 GO:0045022 early endosome to late endosome transport 3/380 40/18722 0.0471681386644609 0.149785526532159 MSN/MAPK1/RAB7A 3 GO:0070266 necroptotic process 3/380 40/18722 0.0471681386644609 0.149785526532159 PELI1/PYGL/CFLAR 3 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 3/380 40/18722 0.0471681386644609 0.149785526532159 BNIP3L/BID/HSPA1A 3 GO:2000781 positive regulation of double-strand break repair 3/380 40/18722 0.0471681386644609 0.149785526532159 SMCHD1/WAS/ACTR2 3 GO:0035914 skeletal muscle cell differentiation 4/380 67/18722 0.0471815566455489 0.149785526532159 FOS/BTG2/EGR1/DDX5 4 GO:0043967 histone H4 acetylation 4/380 67/18722 0.0471815566455489 0.149785526532159 SPI1/MSL1/NCOA1/TAF7 4 GO:0050435 amyloid-beta metabolic process 4/380 67/18722 0.0471815566455489 0.149785526532159 SORL1/RTN3/PICALM/MME 4 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 4/380 67/18722 0.0471815566455489 0.149785526532159 BCL6/NFKBIZ/TGFBR2/CD55 4 GO:0120162 positive regulation of cold-induced thermogenesis 5/380 97/18722 0.0476079134865706 0.1510258528956 G0S2/ACSL1/CEBPB/KDM6B/CXCR4 5 GO:0010976 positive regulation of neuron projection development 7/380 163/18722 0.0489177378050612 0.154833049031715 S100A9/RGS2/LYN/CFLAR/IQGAP1/ACTR2/NFE2L2 7 GO:0061025 membrane fusion 7/380 163/18722 0.0489177378050612 0.154833049031715 GCA/CORO1A/STX3/SAMD9/RAB8B/STX7/RAB7A 7 GO:0071322 cellular response to carbohydrate stimulus 7/380 163/18722 0.0489177378050612 0.154833049031715 PRKCB/CYBA/CLEC7A/ZFP36L1/NADK/HIF1A/PPP3CA 7 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 4/380 68/18722 0.0493612215104731 0.155916310829679 BCL6/IL6R/NFKBIZ/STAT3 4 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 4/380 68/18722 0.0493612215104731 0.155916310829679 LYN/OSM/IL6R/HCLS1 4 GO:0043502 regulation of muscle adaptation 5/380 98/18722 0.0493704304185596 0.155916310829679 RGS2/AIF1/TNFRSF1B/PPP3CA/PAK1 5 GO:0032733 positive regulation of interleukin-10 production 3/380 41/18722 0.0501529720513152 0.157002928755367 CLEC7A/PYCARD/STAT3 3 GO:0042307 positive regulation of protein import into nucleus 3/380 41/18722 0.0501529720513152 0.157002928755367 PTGS2/HCLS1/MAPK1 3 GO:0071634 regulation of transforming growth factor beta production 3/380 41/18722 0.0501529720513152 0.157002928755367 PTGS2/TYROBP/HIF1A 3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 3/380 41/18722 0.0501529720513152 0.157002928755367 PREX1/MYADM/DOCK5 3 GO:2000008 regulation of protein localization to cell surface 3/380 41/18722 0.0501529720513152 0.157002928755367 TYROBP/STX3/PICALM 3 GO:0002295 T-helper cell lineage commitment 2/380 18/18722 0.0507525406059261 0.157002928755367 IL6R/STAT3 2 GO:0002544 chronic inflammatory response 2/380 18/18722 0.0507525406059261 0.157002928755367 S100A8/S100A9 2 GO:0006595 polyamine metabolic process 2/380 18/18722 0.0507525406059261 0.157002928755367 SAT1/OAZ1 2 GO:0010663 positive regulation of striated muscle cell apoptotic process 2/380 18/18722 0.0507525406059261 0.157002928755367 CXCR2/PTEN 2 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 2/380 18/18722 0.0507525406059261 0.157002928755367 CXCR2/PTEN 2 GO:0019896 axonal transport of mitochondrion 2/380 18/18722 0.0507525406059261 0.157002928755367 AGTPBP1/HIF1A 2 GO:0030728 ovulation 2/380 18/18722 0.0507525406059261 0.157002928755367 PTGS2/RGS2 2 GO:0030730 sequestering of triglyceride 2/380 18/18722 0.0507525406059261 0.157002928755367 IL1B/OSBPL8 2 GO:0031649 heat generation 2/380 18/18722 0.0507525406059261 0.157002928755367 PTGS2/IL1B 2 GO:0036499 PERK-mediated unfolded protein response 2/380 18/18722 0.0507525406059261 0.157002928755367 PPP1R15A/NFE2L2 2 GO:0043217 myelin maintenance 2/380 18/18722 0.0507525406059261 0.157002928755367 PTEN/CXCR4 2 GO:0044247 cellular polysaccharide catabolic process 2/380 18/18722 0.0507525406059261 0.157002928755367 MGAM/PYGL 2 GO:0044872 lipoprotein localization 2/380 18/18722 0.0507525406059261 0.157002928755367 PRKCB/VMP1 2 GO:0051447 negative regulation of meiotic cell cycle 2/380 18/18722 0.0507525406059261 0.157002928755367 DUSP1/PRKAR1A 2 GO:0060438 trachea development 2/380 18/18722 0.0507525406059261 0.157002928755367 TGFBR2/MAPK1 2 GO:0060716 labyrinthine layer blood vessel development 2/380 18/18722 0.0507525406059261 0.157002928755367 JUNB/MAPK1 2 GO:0097709 connective tissue replacement 2/380 18/18722 0.0507525406059261 0.157002928755367 HIF1A/PPP3CA 2 GO:0150078 positive regulation of neuroinflammatory response 2/380 18/18722 0.0507525406059261 0.157002928755367 LRRK2/IL1B 2 GO:0150079 negative regulation of neuroinflammatory response 2/380 18/18722 0.0507525406059261 0.157002928755367 PTPRC/TNFRSF1B 2 GO:1901673 regulation of mitotic spindle assembly 2/380 18/18722 0.0507525406059261 0.157002928755367 HSPA1A/VPS4B 2 GO:1902683 regulation of receptor localization to synapse 2/380 18/18722 0.0507525406059261 0.157002928755367 TYROBP/STX7 2 GO:1905820 positive regulation of chromosome separation 2/380 18/18722 0.0507525406059261 0.157002928755367 PLSCR1/CUL3 2 GO:2000641 regulation of early endosome to late endosome transport 2/380 18/18722 0.0507525406059261 0.157002928755367 MSN/MAPK1 2 GO:0006612 protein targeting to membrane 6/380 131/18722 0.0509983870782353 0.157533310923652 NCF1/ITGB2/ZDHHC18/SDCBP/RAB8B/PAK1 6 GO:0046683 response to organophosphorus 6/380 131/18722 0.0509983870782353 0.157533310923652 PTGS2/AQP9/DUSP1/FOS/PTEN/ZFP36L1 6 GO:0045930 negative regulation of mitotic cell cycle 9/380 235/18722 0.0511041814437441 0.157745049864618 BCL6/DUSP1/NABP1/BTG2/PTEN/ZFP36L1/ZFP36L2/BTG1/NBN 9 GO:0002287 alpha-beta T cell activation involved in immune response 4/380 69/18722 0.0515955240558324 0.158840721647892 BCL6/IL6R/NFKBIZ/STAT3 4 GO:0002293 alpha-beta T cell differentiation involved in immune response 4/380 69/18722 0.0515955240558324 0.158840721647892 BCL6/IL6R/NFKBIZ/STAT3 4 GO:0010611 regulation of cardiac muscle hypertrophy 4/380 69/18722 0.0515955240558324 0.158840721647892 RGS2/TNFRSF1B/PPP3CA/PAK1 4 GO:0050796 regulation of insulin secretion 7/380 165/18722 0.0516091695365997 0.158840721647892 ALOX5/MIDN/IL1B/GLUL/NADK/HIF1A/PPP3CA 7 GO:0016570 histone modification 15/380 463/18722 0.0516805189677863 0.158944805975726 LRRK2/BCL6/SPI1/PRKCB/KDM6B/IL1B/MSL1/JMJD1C/USP15/UBE2B/NCOA1/TAF7/KDM5A/TET2/PHF20L1 15 GO:0090068 positive regulation of cell cycle process 9/380 236/18722 0.0522279659678561 0.160511927339529 AIF1/IL1B/PLSCR1/UBE2B/DDX3X/CUL3/VPS4B/PHIP/TMOD3 9 GO:0034249 negative regulation of cellular amide metabolic process 10/380 273/18722 0.0527232776511615 0.16191666486778 RGS2/SORL1/ZFP36/BTG2/ZFP36L1/RTN3/ZFP36L2/STAT3/DDX3X/CPEB4 10 GO:0030307 positive regulation of cell growth 7/380 166/18722 0.0529892063346571 0.162288456386516 S100A8/S100A9/CYBA/SDCBP/CXCR4/DDX3X/PAK1 7 GO:0006641 triglyceride metabolic process 5/380 100/18722 0.0530094965502204 0.162288456386516 SORL1/ACSL1/MBOAT7/LPGAT1/CAT 5 GO:0051054 positive regulation of DNA metabolic process 8/380 201/18722 0.0531542276639621 0.162288456386516 PTPRC/SMCHD1/WAS/ARRB2/ACTR2/UBE2B/MAPK1/NBN 8 GO:0007520 myoblast fusion 3/380 42/18722 0.0532275480332634 0.162288456386516 CFLAR/CD53/MYH9 3 GO:0010677 negative regulation of cellular carbohydrate metabolic process 3/380 42/18722 0.0532275480332634 0.162288456386516 PLEK/MIDN/STAT3 3 GO:0010939 regulation of necrotic cell death 3/380 42/18722 0.0532275480332634 0.162288456386516 PELI1/CFLAR/TSPO 3 GO:0014912 negative regulation of smooth muscle cell migration 3/380 42/18722 0.0532275480332634 0.162288456386516 AIF1/TRIB1/NFE2L2 3 GO:0016601 Rac protein signal transduction 3/380 42/18722 0.0532275480332634 0.162288456386516 AIF1/RAC2/RHOG 3 GO:0045687 positive regulation of glial cell differentiation 3/380 42/18722 0.0532275480332634 0.162288456386516 CXCR4/TNFRSF1B/DICER1 3 GO:0048489 synaptic vesicle transport 3/380 42/18722 0.0532275480332634 0.162288456386516 LRRK2/RAB27A/PICALM 3 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 4/380 70/18722 0.0538843004049823 0.164054645733357 PTPRC/BCL6/B2M/NBN 4 GO:0045123 cellular extravasation 4/380 70/18722 0.0538843004049823 0.164054645733357 SELL/JAML/CD177/PECAM1 4 GO:0046328 regulation of JNK cascade 6/380 133/18722 0.0541465976562086 0.164734799622158 NCF1/RASSF2/IL1B/SDCBP/PYCARD/PJA2 6 GO:0019439 aromatic compound catabolic process 15/380 467/18722 0.0548662554098928 0.166804444839121 CDA/ZFP36/SLC11A1/APOBEC3A/VIM/BTG2/TNFRSF1B/ZFP36L1/RNASET2/TYMP/ZFP36L2/DICER1/DDX5/HSPA1A/TET2 15 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 6/380 134/18722 0.0557639414783368 0.168021250496571 LRRK2/TRIB1/SDCBP/HSPA1A/NFE2L2/N4BP1 6 GO:0099173 postsynapse organization 7/380 168/18722 0.0558182521423987 0.168021250496571 SRGN/LRRK2/ACTB/LILRB2/PTEN/ACTR2/ACTN1 7 GO:0008356 asymmetric cell division 2/380 19/18722 0.0559806338726473 0.168021250496571 ACTR2/ACTR3 2 GO:0010738 regulation of protein kinase A signaling 2/380 19/18722 0.0559806338726473 0.168021250496571 LRRK2/PJA2 2 GO:0010759 positive regulation of macrophage chemotaxis 2/380 19/18722 0.0559806338726473 0.168021250496571 C5AR1/MAPK1 2 GO:0031065 positive regulation of histone deacetylation 2/380 19/18722 0.0559806338726473 0.168021250496571 LRRK2/BCL6 2 GO:0032695 negative regulation of interleukin-12 production 2/380 19/18722 0.0559806338726473 0.168021250496571 IRAK3/ARRB2 2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 2/380 19/18722 0.0559806338726473 0.168021250496571 ACSL1/ELOVL5 2 GO:0043652 engulfment of apoptotic cell 2/380 19/18722 0.0559806338726473 0.168021250496571 RAC2/RHOG 2 GO:0044320 cellular response to leptin stimulus 2/380 19/18722 0.0559806338726473 0.168021250496571 PTEN/STAT3 2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 2/380 19/18722 0.0559806338726473 0.168021250496571 CXCL8/APOBEC3A 2 GO:0046782 regulation of viral transcription 2/380 19/18722 0.0559806338726473 0.168021250496571 ZFP36/IFITM3 2 GO:0050961 detection of temperature stimulus involved in sensory perception 2/380 19/18722 0.0559806338726473 0.168021250496571 ARRB2/CXCR4 2 GO:0060216 definitive hemopoiesis 2/380 19/18722 0.0559806338726473 0.168021250496571 ZFP36L2/ADAR 2 GO:0070233 negative regulation of T cell apoptotic process 2/380 19/18722 0.0559806338726473 0.168021250496571 TSC22D3/HIF1A 2 GO:1901739 regulation of myoblast fusion 2/380 19/18722 0.0559806338726473 0.168021250496571 CFLAR/CD53 2 GO:1903978 regulation of microglial cell activation 2/380 19/18722 0.0559806338726473 0.168021250496571 PTPRC/LRRK2 2 GO:2000251 positive regulation of actin cytoskeleton reorganization 2/380 19/18722 0.0559806338726473 0.168021250496571 HCK/HCLS1 2 GO:0035794 positive regulation of mitochondrial membrane permeability 3/380 43/18722 0.0563906991257409 0.16817930337853 BNIP3L/BID/HSPA1A 3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3/380 43/18722 0.0563906991257409 0.16817930337853 PYCARD/IFI16/CD44 3 GO:0045840 positive regulation of mitotic nuclear division 3/380 43/18722 0.0563906991257409 0.16817930337853 IL1B/CUL3/PHIP 3 GO:0045981 positive regulation of nucleotide metabolic process 3/380 43/18722 0.0563906991257409 0.16817930337853 TMSB4X/STAT3/HIF1A 3 GO:0071604 transforming growth factor beta production 3/380 43/18722 0.0563906991257409 0.16817930337853 PTGS2/TYROBP/HIF1A 3 GO:0120178 steroid hormone biosynthetic process 3/380 43/18722 0.0563906991257409 0.16817930337853 TSPO/EGR1/HSD17B11 3 GO:1900544 positive regulation of purine nucleotide metabolic process 3/380 43/18722 0.0563906991257409 0.16817930337853 TMSB4X/STAT3/HIF1A 3 GO:1904591 positive regulation of protein import 3/380 43/18722 0.0563906991257409 0.16817930337853 PTGS2/HCLS1/MAPK1 3 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 3/380 43/18722 0.0563906991257409 0.16817930337853 MCL1/IL1B/HSPA1A 3 GO:0071383 cellular response to steroid hormone stimulus 8/380 204/18722 0.0570005813131484 0.169878579775639 ZFP36/CFLAR/ZFP36L1/ZFP36L2/TAF7/DDX5/PAK1/NCOA4 8 GO:0021543 pallium development 7/380 169/18722 0.0572673767079961 0.170553685202787 BCL2A1/MBOAT7/KDM6B/BTG2/PTEN/NCOA1/HIF1A 7 GO:0044843 cell cycle G1/S phase transition 9/380 241/18722 0.0580892996872474 0.172879960769847 AIF1/CDKN2D/PTEN/BID/DDX3X/PTPN6/CUL3/PPP3CA/BACH1 9 GO:0014743 regulation of muscle hypertrophy 4/380 72/18722 0.058624459499097 0.173861754887028 RGS2/TNFRSF1B/PPP3CA/PAK1 4 GO:0030032 lamellipodium assembly 4/380 72/18722 0.058624459499097 0.173861754887028 RAC2/WAS/ACTR2/ACTR3 4 GO:0030330 DNA damage response, signal transduction by p53 class mediator 4/380 72/18722 0.058624459499097 0.173861754887028 CD44/USP10/DDX5/NBN 4 GO:0050709 negative regulation of protein secretion 4/380 72/18722 0.058624459499097 0.173861754887028 MIDN/IL1B/RAB11FIP1/PPP3CA 4 GO:0071479 cellular response to ionizing radiation 4/380 72/18722 0.058624459499097 0.173861754887028 NAMPT/CYBA/EGR1/IFI16 4 GO:0043487 regulation of RNA stability 7/380 170/18722 0.0587396368447931 0.17408142899769 ZFP36/SLC11A1/VIM/BTG2/TNFRSF1B/ZFP36L1/ZFP36L2 7 GO:0021762 substantia nigra development 3/380 44/18722 0.0596411938454724 0.176506258515427 BASP1/ACTB/MBP 3 GO:0097178 ruffle assembly 3/380 44/18722 0.0596411938454724 0.176506258515427 AIF1/SNX10/RHOG 3 GO:0046890 regulation of lipid biosynthetic process 7/380 171/18722 0.0602350764576943 0.178066212085282 PTGS2/ELOVL5/IL1B/TSPO/LPGAT1/EGR1/SF1 7 GO:0016358 dendrite development 9/380 243/18722 0.060547930176894 0.178066212085282 LST1/LRRK2/PREX1/PTEN/IQGAP1/ACTR2/PICALM/PPP3CA/PAK2 9 GO:0043543 protein acylation 9/380 243/18722 0.060547930176894 0.178066212085282 SPI1/IL1B/MSL1/ZDHHC18/GLUL/NCOA1/DDX3X/TAF7/PHF20L1 9 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 5/380 104/18722 0.0607439564584317 0.178066212085282 CXCR2/FPR1/C5AR1/FPR2/GPR65 5 GO:0014896 muscle hypertrophy 5/380 104/18722 0.0607439564584317 0.178066212085282 RGS2/CYBA/TNFRSF1B/PPP3CA/PAK1 5 GO:0032963 collagen metabolic process 5/380 104/18722 0.0607439564584317 0.178066212085282 MMP25/CTSS/VIM/ARRB2/HIF1A 5 GO:0045621 positive regulation of lymphocyte differentiation 5/380 104/18722 0.0607439564584317 0.178066212085282 PTPRC/BCL6/LILRB2/NFKBIZ/TGFBR2 5 GO:0016064 immunoglobulin mediated immune response 8/380 207/18722 0.0610194220838915 0.178066212085282 PTPRC/FCER1G/BCL6/B2M/HLA-E/CD55/PTPN6/NBN 8 GO:0032456 endocytic recycling 4/380 73/18722 0.0610753574384494 0.178066212085282 SORL1/ACAP2/CMTM6/RAB7A 4 GO:0050848 regulation of calcium-mediated signaling 4/380 73/18722 0.0610753574384494 0.178066212085282 LRRK2/PLEK/CLEC7A/TMBIM4 4 GO:0000272 polysaccharide catabolic process 2/380 20/18722 0.0613876433635211 0.178066212085282 MGAM/PYGL 2 GO:0003159 morphogenesis of an endothelium 2/380 20/18722 0.0613876433635211 0.178066212085282 ITGAX/CXCR4 2 GO:0006700 C21-steroid hormone biosynthetic process 2/380 20/18722 0.0613876433635211 0.178066212085282 TSPO/EGR1 2 GO:0016553 base conversion or substitution editing 2/380 20/18722 0.0613876433635211 0.178066212085282 APOBEC3A/ADAR 2 GO:0039535 regulation of RIG-I signaling pathway 2/380 20/18722 0.0613876433635211 0.178066212085282 SEC14L1/USP15 2 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 2/380 20/18722 0.0613876433635211 0.178066212085282 CXCL8/APOBEC3A 2 GO:0043011 myeloid dendritic cell differentiation 2/380 20/18722 0.0613876433635211 0.178066212085282 SPI1/TGFBR2 2 GO:0043555 regulation of translation in response to stress 2/380 20/18722 0.0613876433635211 0.178066212085282 DDX3X/PPP1R15A 2 GO:0043651 linoleic acid metabolic process 2/380 20/18722 0.0613876433635211 0.178066212085282 ELOVL5/ALOX5 2 GO:0046629 gamma-delta T cell activation 2/380 20/18722 0.0613876433635211 0.178066212085282 PTPRC/JAML 2 GO:0051900 regulation of mitochondrial depolarization 2/380 20/18722 0.0613876433635211 0.178066212085282 LRRK2/TSPO 2 GO:0060044 negative regulation of cardiac muscle cell proliferation 2/380 20/18722 0.0613876433635211 0.178066212085282 PTEN/TGFBR2 2 GO:0061154 endothelial tube morphogenesis 2/380 20/18722 0.0613876433635211 0.178066212085282 ITGAX/CXCR4 2 GO:0061318 renal filtration cell differentiation 2/380 20/18722 0.0613876433635211 0.178066212085282 BASP1/IQGAP1 2 GO:0071731 response to nitric oxide 2/380 20/18722 0.0613876433635211 0.178066212085282 CFLAR/EGLN1 2 GO:0072112 glomerular visceral epithelial cell differentiation 2/380 20/18722 0.0613876433635211 0.178066212085282 BASP1/IQGAP1 2 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 2/380 20/18722 0.0613876433635211 0.178066212085282 LRRK2/NFE2L2 2 GO:2000010 positive regulation of protein localization to cell surface 2/380 20/18722 0.0613876433635211 0.178066212085282 TYROBP/STX3 2 GO:2000757 negative regulation of peptidyl-lysine acetylation 2/380 20/18722 0.0613876433635211 0.178066212085282 SPI1/TAF7 2 GO:1901136 carbohydrate derivative catabolic process 7/380 172/18722 0.0617537338916469 0.179005518844028 PGLYRP1/CDA/APOBEC3A/TYMP/IDS/CD44/CTBS 7 GO:0032231 regulation of actin filament bundle assembly 5/380 105/18722 0.0627724969143054 0.181834148038361 PLEK/WAS/GPR65/PAK2/PAK1 5 GO:0044088 regulation of vacuole organization 3/380 45/18722 0.0629777412606839 0.181930923764663 LRRK2/RALB/SH3GLB1 3 GO:0045933 positive regulation of muscle contraction 3/380 45/18722 0.0629777412606839 0.181930923764663 PTGS2/RGS2/PROK2 3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 3/380 45/18722 0.0629777412606839 0.181930923764663 BNIP3L/BID/HSPA1A 3 GO:2000273 positive regulation of signaling receptor activity 3/380 45/18722 0.0629777412606839 0.181930923764663 NCF1/IFNGR2/HIF1A 3 GO:0009306 protein secretion 12/380 359/18722 0.0634967446580254 0.183170264486548 HCAR2/PLEK/ALOX5/MIDN/IL1B/GLUL/RAB11FIP1/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 12 GO:0046323 glucose import 4/380 74/18722 0.0635797612267356 0.183170264486548 SLC2A3/OSBPL8/STXBP3/NFE2L2 4 GO:0051881 regulation of mitochondrial membrane potential 4/380 74/18722 0.0635797612267356 0.183170264486548 LRRK2/TSPO/BNIP3L/BID 4 GO:1901568 fatty acid derivative metabolic process 4/380 74/18722 0.0635797612267356 0.183170264486548 ACSL1/CYP4F3/ELOVL5/ALOX5 4 GO:0051146 striated muscle cell differentiation 10/380 283/18722 0.0639544250189388 0.184124398338005 RGS2/KDM6B/ARRB2/CFLAR/CD53/PRKAR1A/MYH9/PPP3CA/PAK1/TMOD3 10 GO:0051783 regulation of nuclear division 6/380 139/18722 0.0642844583670295 0.184948832326338 DUSP1/IL1B/PRKAR1A/UBE2B/CUL3/PHIP 6 GO:0035592 establishment of protein localization to extracellular region 12/380 360/18722 0.0645474697648331 0.18557945312564 HCAR2/PLEK/ALOX5/MIDN/IL1B/GLUL/RAB11FIP1/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 12 GO:0002793 positive regulation of peptide secretion 5/380 106/18722 0.0648388967152885 0.186290859965568 S100A8/GLUL/NADK/HIF1A/RAB8B 5 GO:0019724 B cell mediated immunity 8/380 210/18722 0.0652119634838709 0.187235705324877 PTPRC/FCER1G/BCL6/B2M/HLA-E/CD55/PTPN6/NBN 8 GO:0006984 ER-nucleus signaling pathway 3/380 46/18722 0.0663989953543604 0.188810497608447 BID/PPP1R15A/NFE2L2 3 GO:1900271 regulation of long-term synaptic potentiation 3/380 46/18722 0.0663989953543604 0.188810497608447 TYROBP/LILRB2/MME 3 GO:0030100 regulation of endocytosis 8/380 211/18722 0.0666482435963541 0.188810497608447 LRRK2/CD177/B2M/ARRB2/SDCBP/NUMB/PICALM/PPP3CA 8 GO:0043491 protein kinase B signaling 8/380 211/18722 0.0666482435963541 0.188810497608447 OSM/IL1B/ARRB2/PTEN/ZFP36L1/OSBPL8/HCLS1/RICTOR 8 GO:0021761 limbic system development 5/380 107/18722 0.0669430739513955 0.188810497608447 KDM6B/BTG2/PTEN/ARPC5/NCOA1 5 GO:0032526 response to retinoic acid 5/380 107/18722 0.0669430739513955 0.188810497608447 LYN/DUSP1/CDKN2D/IGF2R/NCOA1 5 GO:0006925 inflammatory cell apoptotic process 2/380 21/18722 0.0669641953737632 0.188810497608447 CXCR2/HCAR2 2 GO:0007617 mating behavior 2/380 21/18722 0.0669641953737632 0.188810497608447 PTEN/NCOA1 2 GO:0019370 leukotriene biosynthetic process 2/380 21/18722 0.0669641953737632 0.188810497608447 ALOX5AP/ALOX5 2 GO:0030449 regulation of complement activation 2/380 21/18722 0.0669641953737632 0.188810497608447 IL1B/CD55 2 GO:0030502 negative regulation of bone mineralization 2/380 21/18722 0.0669641953737632 0.188810497608447 SRGN/HIF1A 2 GO:0032516 positive regulation of phosphoprotein phosphatase activity 2/380 21/18722 0.0669641953737632 0.188810497608447 PTPRC/PPP1R15A 2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 2/380 21/18722 0.0669641953737632 0.188810497608447 GMFG/WAS 2 GO:0042454 ribonucleoside catabolic process 2/380 21/18722 0.0669641953737632 0.188810497608447 CDA/APOBEC3A 2 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 2/380 21/18722 0.0669641953737632 0.188810497608447 IL6R/STAT3 2 GO:0045056 transcytosis 2/380 21/18722 0.0669641953737632 0.188810497608447 PICALM/FCGRT 2 GO:0046885 regulation of hormone biosynthetic process 2/380 21/18722 0.0669641953737632 0.188810497608447 EGR1/HIF1A 2 GO:0048714 positive regulation of oligodendrocyte differentiation 2/380 21/18722 0.0669641953737632 0.188810497608447 CXCR4/TNFRSF1B 2 GO:0051767 nitric-oxide synthase biosynthetic process 2/380 21/18722 0.0669641953737632 0.188810497608447 NAMPT/LRRK2 2 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 2/380 21/18722 0.0669641953737632 0.188810497608447 NAMPT/LRRK2 2 GO:0071605 monocyte chemotactic protein-1 production 2/380 21/18722 0.0669641953737632 0.188810497608447 IL1B/CLEC7A 2 GO:0071637 regulation of monocyte chemotactic protein-1 production 2/380 21/18722 0.0669641953737632 0.188810497608447 IL1B/CLEC7A 2 GO:0072311 glomerular epithelial cell differentiation 2/380 21/18722 0.0669641953737632 0.188810497608447 BASP1/IQGAP1 2 GO:0090026 positive regulation of monocyte chemotaxis 2/380 21/18722 0.0669641953737632 0.188810497608447 FPR2/AIF1 2 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 2/380 21/18722 0.0669641953737632 0.188810497608447 CFLAR/STAT3 2 GO:1903429 regulation of cell maturation 2/380 21/18722 0.0669641953737632 0.188810497608447 LRRK2/CLEC7A 2 GO:2000774 positive regulation of cellular senescence 2/380 21/18722 0.0669641953737632 0.188810497608447 B2M/YPEL3 2 GO:0048284 organelle fusion 6/380 141/18722 0.0678953491236288 0.191308585188668 CORO1A/STX3/SAMD9/RAB8B/STX7/RAB7A 6 GO:0043536 positive regulation of blood vessel endothelial cell migration 4/380 76/18722 0.0687477945842002 0.193453096388098 PTGS2/TMSB4X/HIF1A/NFE2L2 4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 4/380 76/18722 0.0687477945842002 0.193453096388098 PYCARD/IFI16/CD44/DDX5 4 GO:0007173 epidermal growth factor receptor signaling pathway 5/380 108/18722 0.0690849318998426 0.194272700262838 NCF1/PLAUR/RASSF2/IQGAP1/RAB7A 5 GO:0051302 regulation of cell division 7/380 177/18722 0.0696962412705316 0.195665283040877 EVI2B/OSM/TXNIP/IL1B/CUL3/SH3GLB1/CAT 7 GO:0072006 nephron development 6/380 142/18722 0.0697442002253003 0.195665283040877 BASP1/IL6R/PECAM1/CFLAR/IQGAP1/EGR1 6 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 3/380 47/18722 0.0699035592068115 0.195665283040877 SOD2/CYBA/MME 3 GO:0042311 vasodilation 3/380 47/18722 0.0699035592068115 0.195665283040877 SOD2/RGS2/KLF2 3 GO:0045581 negative regulation of T cell differentiation 3/380 47/18722 0.0699035592068115 0.195665283040877 BCL6/FGL2/IRF1 3 GO:0061001 regulation of dendritic spine morphogenesis 3/380 47/18722 0.0699035592068115 0.195665283040877 LRRK2/PTEN/ACTR2 3 GO:0097300 programmed necrotic cell death 3/380 47/18722 0.0699035592068115 0.195665283040877 PELI1/PYGL/CFLAR 3 GO:0009266 response to temperature stimulus 7/380 178/18722 0.0713546996463859 0.199488360165323 SOD2/PTGS2/LYN/FOS/ARRB2/CXCR4/HSPA1A 7 GO:0002200 somatic diversification of immune receptors 4/380 77/18722 0.0714107093295466 0.199488360165323 PTPRC/BCL6/ADAR/NBN 4 GO:1901983 regulation of protein acetylation 4/380 77/18722 0.0714107093295466 0.199488360165323 SPI1/IL1B/DDX3X/TAF7 4 GO:0034763 negative regulation of transmembrane transport 6/380 143/18722 0.0716219535619462 0.199946587564168 RGS2/PRKCB/IL1B/PTEN/OAZ1/STXBP3 6 GO:0051271 negative regulation of cellular component movement 12/380 367/18722 0.0722231466197746 0.200579590830609 IFITM1/AIF1/DUSP1/TRIB1/WAS/ARHGDIB/CNN2/PTEN/OSBPL8/STAT3/ACTN1/NFE2L2 12 GO:0002320 lymphoid progenitor cell differentiation 2/380 22/18722 0.0727012212337627 0.200579590830609 SPI1/SOS2 2 GO:0032816 positive regulation of natural killer cell activation 2/380 22/18722 0.0727012212337627 0.200579590830609 TYROBP/HLA-E 2 GO:0034629 cellular protein-containing complex localization 2/380 22/18722 0.0727012212337627 0.200579590830609 TNFAIP2/RALB 2 GO:0034755 iron ion transmembrane transport 2/380 22/18722 0.0727012212337627 0.200579590830609 SLC25A37/SLC11A1 2 GO:0035024 negative regulation of Rho protein signal transduction 2/380 22/18722 0.0727012212337627 0.200579590830609 BCL6/CUL3 2 GO:0050860 negative regulation of T cell receptor signaling pathway 2/380 22/18722 0.0727012212337627 0.200579590830609 LAPTM5/PTPN6 2 GO:0060713 labyrinthine layer morphogenesis 2/380 22/18722 0.0727012212337627 0.200579590830609 ZFP36L1/NCOA1 2 GO:0061042 vascular wound healing 2/380 22/18722 0.0727012212337627 0.200579590830609 ALOX5/CXCR4 2 GO:0071404 cellular response to low-density lipoprotein particle stimulus 2/380 22/18722 0.0727012212337627 0.200579590830609 FCER1G/ITGB2 2 GO:0072574 hepatocyte proliferation 2/380 22/18722 0.0727012212337627 0.200579590830609 CEBPB/CFLAR 2 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 2/380 22/18722 0.0727012212337627 0.200579590830609 CEBPB/CFLAR 2 GO:0140467 integrated stress response signaling 2/380 22/18722 0.0727012212337627 0.200579590830609 PPP1R15A/NFE2L2 2 GO:1901032 negative regulation of response to reactive oxygen species 2/380 22/18722 0.0727012212337627 0.200579590830609 LRRK2/NFE2L2 2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 2/380 22/18722 0.0727012212337627 0.200579590830609 HIF1A/NFE2L2 2 GO:2000114 regulation of establishment of cell polarity 2/380 22/18722 0.0727012212337627 0.200579590830609 RICTOR/FLOT2 2 GO:2000193 positive regulation of fatty acid transport 2/380 22/18722 0.0727012212337627 0.200579590830609 ACSL1/IL1B 2 GO:2000773 negative regulation of cellular senescence 2/380 22/18722 0.0727012212337627 0.200579590830609 NAMPT/BCL6 2 GO:0071692 protein localization to extracellular region 12/380 368/18722 0.0733657727542534 0.201941312200236 HCAR2/PLEK/ALOX5/MIDN/IL1B/GLUL/RAB11FIP1/NADK/HIF1A/RAB8B/STXBP3/PPP3CA 12 GO:0048259 regulation of receptor-mediated endocytosis 5/380 110/18722 0.0734812302633676 0.201941312200236 B2M/ARRB2/SDCBP/NUMB/PICALM 5 GO:0010569 regulation of double-strand break repair via homologous recombination 3/380 48/18722 0.0734899890036179 0.201941312200236 SMCHD1/WAS/ACTR2 3 GO:0045912 negative regulation of carbohydrate metabolic process 3/380 48/18722 0.0734899890036179 0.201941312200236 PLEK/MIDN/STAT3 3 GO:0090311 regulation of protein deacetylation 3/380 48/18722 0.0734899890036179 0.201941312200236 LRRK2/BCL6/KDM5A 3 GO:1902003 regulation of amyloid-beta formation 3/380 48/18722 0.0734899890036179 0.201941312200236 SORL1/RTN3/PICALM 3 GO:0031644 regulation of nervous system process 6/380 144/18722 0.0735285722344188 0.201941312200236 LRRK2/ITGAX/PTEN/TNFRSF1B/TYMP/DICER1 6 GO:0060485 mesenchyme development 10/380 291/18722 0.0739729186247171 0.203030013205235 BASP1/S100A4/IL1B/PTEN/SDCBP/ZFP36L1/TGFBR2/HIF1A/DDX5/MAPK1 10 GO:0008306 associative learning 4/380 78/18722 0.0741257019659105 0.203185985647658 FOS/BTG2/ACTR2/HIF1A 4 GO:0070373 negative regulation of ERK1 and ERK2 cascade 4/380 78/18722 0.0741257019659105 0.203185985647658 PTPRC/LYN/DUSP1/PTEN 4 GO:0010721 negative regulation of cell development 7/380 180/18722 0.0747416026894218 0.204741712412485 SORL1/B2M/IL1B/TSPO/PTEN/DICER1/PPP3CA 7 GO:0061351 neural precursor cell proliferation 6/380 145/18722 0.0754640108514464 0.20658699803224 LRRK2/C5AR1/LYN/BTG2/NUMB/HIF1A 6 GO:0001938 positive regulation of endothelial cell proliferation 5/380 111/18722 0.0757354051200479 0.207196021113309 LRG1/CYBA/STAT3/RICTOR/HIF1A 5 GO:0001822 kidney development 10/380 293/18722 0.0766230547226669 0.209192726632516 CXCR2/LRRK2/BASP1/IL6R/PECAM1/CFLAR/IQGAP1/EGR1/MME/CAT 10 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 4/380 79/18722 0.0768923499438306 0.209192726632516 PREX1/MYADM/ACTR2/DOCK5 4 GO:0051279 regulation of release of sequestered calcium ion into cytosol 4/380 79/18722 0.0768923499438306 0.209192726632516 LYN/CORO1A/CYBA/PTPN6 4 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 4/380 79/18722 0.0768923499438306 0.209192726632516 S100A12/CXCL8/S100A9/PGLYRP1 4 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 3/380 49/18722 0.0771567978748501 0.209192726632516 PTPRC/BCL6/NBN 3 GO:0002208 somatic diversification of immunoglobulins involved in immune response 3/380 49/18722 0.0771567978748501 0.209192726632516 PTPRC/BCL6/NBN 3 GO:0002762 negative regulation of myeloid leukocyte differentiation 3/380 49/18722 0.0771567978748501 0.209192726632516 LYN/LILRB3/TRIB1 3 GO:0010823 negative regulation of mitochondrion organization 3/380 49/18722 0.0771567978748501 0.209192726632516 ARRB2/TSPO/HSPA1A 3 GO:0018198 peptidyl-cysteine modification 3/380 49/18722 0.0771567978748501 0.209192726632516 S100A8/S100A9/ZDHHC18 3 GO:0030225 macrophage differentiation 3/380 49/18722 0.0771567978748501 0.209192726632516 SPI1/TRIB1/HCLS1 3 GO:0034332 adherens junction organization 3/380 49/18722 0.0771567978748501 0.209192726632516 ACTB/NUMB/PAK2 3 GO:0043330 response to exogenous dsRNA 3/380 49/18722 0.0771567978748501 0.209192726632516 IRAK3/RALB/MAPK1 3 GO:0045190 isotype switching 3/380 49/18722 0.0771567978748501 0.209192726632516 PTPRC/BCL6/NBN 3 GO:0051445 regulation of meiotic cell cycle 3/380 49/18722 0.0771567978748501 0.209192726632516 DUSP1/PRKAR1A/UBE2B 3 GO:0000956 nuclear-transcribed mRNA catabolic process 5/380 112/18722 0.0780267300314999 0.210650907180912 ZFP36/BTG2/ZFP36L1/ZFP36L2/DDX5 5 GO:0001676 long-chain fatty acid metabolic process 5/380 112/18722 0.0780267300314999 0.210650907180912 PTGS2/ACSL1/CYP4F3/ELOVL5/ALOX5 5 GO:0043406 positive regulation of MAP kinase activity 5/380 112/18722 0.0780267300314999 0.210650907180912 S100A12/LRRK2/IL1B/IQGAP1/PAK1 5 GO:0048640 negative regulation of developmental growth 5/380 112/18722 0.0780267300314999 0.210650907180912 RGS2/PTEN/STK4/TGFBR2/PAK1 5 GO:0051260 protein homooligomerization 7/380 182/18722 0.078221753595427 0.210650907180912 SOD2/STEAP4/ALOX5AP/B2M/PYCARD/VASP/RNF213 7 GO:0002363 alpha-beta T cell lineage commitment 2/380 23/18722 0.078589948841993 0.210650907180912 IL6R/STAT3 2 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 2/380 23/18722 0.078589948841993 0.210650907180912 CYBA/MME 2 GO:0019430 removal of superoxide radicals 2/380 23/18722 0.078589948841993 0.210650907180912 SOD2/NFE2L2 2 GO:0042026 protein refolding 2/380 23/18722 0.078589948841993 0.210650907180912 B2M/HSPA1A 2 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 2/380 23/18722 0.078589948841993 0.210650907180912 IL6R/STAT3 2 GO:0045980 negative regulation of nucleotide metabolic process 2/380 23/18722 0.078589948841993 0.210650907180912 CDA/STAT3 2 GO:0051882 mitochondrial depolarization 2/380 23/18722 0.078589948841993 0.210650907180912 LRRK2/TSPO 2 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 2/380 23/18722 0.078589948841993 0.210650907180912 TYROBP/CD53 2 GO:0060353 regulation of cell adhesion molecule production 2/380 23/18722 0.078589948841993 0.210650907180912 CXCL8/IL1B 2 GO:0060396 growth hormone receptor signaling pathway 2/380 23/18722 0.078589948841993 0.210650907180912 LYN/STAT3 2 GO:0061050 regulation of cell growth involved in cardiac muscle cell development 2/380 23/18722 0.078589948841993 0.210650907180912 RGS2/PAK1 2 GO:1903306 negative regulation of regulated secretory pathway 2/380 23/18722 0.078589948841993 0.210650907180912 SPI1/STXBP3 2 GO:2001169 regulation of ATP biosynthetic process 2/380 23/18722 0.078589948841993 0.210650907180912 TMSB4X/STAT3 2 GO:2001020 regulation of response to DNA damage stimulus 8/380 219/18722 0.0788393743327614 0.211185800315778 SMCHD1/CDKN2D/WAS/MCL1/ACTR2/CD44/BID/DDX5 8 GO:0062012 regulation of small molecule metabolic process 11/380 334/18722 0.0796164795118581 0.213114092913262 PTGS2/CDA/TMSB4X/PLEK/ELOVL5/MIDN/IL1B/LPGAT1/EGR1/STAT3/HIF1A 11 GO:0021766 hippocampus development 4/380 80/18722 0.0797102061805447 0.213114092913262 KDM6B/BTG2/PTEN/NCOA1 4 GO:0071229 cellular response to acid chemical 4/380 80/18722 0.0797102061805447 0.213114092913262 KLF2/CYBA/CEBPB/CPEB4 4 GO:0044344 cellular response to fibroblast growth factor stimulus 5/380 113/18722 0.0803550375389912 0.214702576642036 CXCL8/ZFP36/ZFP36L1/ZFP36L2/CD44 5 GO:0031503 protein-containing complex localization 8/380 220/18722 0.0804510156029216 0.214823487439075 TYROBP/STX3/TNFAIP2/RALB/NUMB/NUP214/STX7/ZC3H11A 8 GO:0001558 regulation of cell growth 13/380 414/18722 0.0807130234522714 0.215350041662068 S100A8/S100A9/RGS2/CDA/BCL6/CDKN2D/CYBA/SDCBP/CXCR4/BTG1/DDX3X/HSPA1A/PAK1 13 GO:0045058 T cell selection 3/380 50/18722 0.0809024595712751 0.215350041662068 PTPRC/IL6R/STAT3 3 GO:0051646 mitochondrion localization 3/380 50/18722 0.0809024595712751 0.215350041662068 LRRK2/AGTPBP1/HIF1A 3 GO:0071709 membrane assembly 3/380 50/18722 0.0809024595712751 0.215350041662068 PTEN/PICALM/FLOT2 3 GO:1901570 fatty acid derivative biosynthetic process 3/380 50/18722 0.0809024595712751 0.215350041662068 ACSL1/ELOVL5/ALOX5 3 GO:0042593 glucose homeostasis 9/380 258/18722 0.0811003931303473 0.215741309614963 FFAR2/PYGL/ALOX5/CYBA/STAT3/NADK/HIF1A/STXBP3/PPP3CA 9 GO:0010212 response to ionizing radiation 6/380 148/18722 0.081442666581865 0.216379983045294 NAMPT/PTPRC/NABP1/CYBA/EGR1/IFI16 6 GO:0014074 response to purine-containing compound 6/380 148/18722 0.081442666581865 0.216379983045294 PTGS2/AQP9/DUSP1/FOS/PTEN/ZFP36L1 6 GO:0055001 muscle cell development 7/380 184/18722 0.0817949953793455 0.217179815317573 RGS2/CFLAR/PRKAR1A/ACTN1/PPP3CA/PAK1/TMOD3 7 GO:0008406 gonad development 8/380 221/18722 0.0820821531503307 0.217669329111866 BASP1/CEBPB/ARRB2/TNFSF10/NCOA1/KDM5A/SF1/NCOA4 8 GO:0010810 regulation of cell-substrate adhesion 8/380 221/18722 0.0820821531503307 0.217669329111866 RAC2/BCL6/PREX1/MYADM/PTEN/IQGAP1/STK4/DOCK5 8 GO:0001960 negative regulation of cytokine-mediated signaling pathway 4/380 81/18722 0.0825787999031299 0.218369908688661 PTPRC/IRAK3/CARD16/ADAR 4 GO:0021954 central nervous system neuron development 4/380 81/18722 0.0825787999031299 0.218369908688661 BTG2/PTEN/AGTPBP1/NIN 4 GO:0030641 regulation of cellular pH 4/380 81/18722 0.0825787999031299 0.218369908688661 LRRK2/SLC11A1/MAPK1/RAB7A 4 GO:2001021 negative regulation of response to DNA damage stimulus 4/380 81/18722 0.0825787999031299 0.218369908688661 SMCHD1/CDKN2D/CD44/BID 4 GO:0033500 carbohydrate homeostasis 9/380 259/18722 0.0826041543610944 0.218369908688661 FFAR2/PYGL/ALOX5/CYBA/STAT3/NADK/HIF1A/STXBP3/PPP3CA 9 GO:0090150 establishment of protein localization to membrane 9/380 260/18722 0.0841246642039414 0.220943423490389 NCF1/ITGB2/ZDHHC18/SDCBP/STX3/BID/RAB8B/PAK1/RAB7A 9 GO:0002438 acute inflammatory response to antigenic stimulus 2/380 24/18722 0.0846218944145295 0.220943423490389 CXCR2/HLA-E 2 GO:0002922 positive regulation of humoral immune response 2/380 24/18722 0.0846218944145295 0.220943423490389 PTPRC/IL1B 2 GO:0010226 response to lithium ion 2/380 24/18722 0.0846218944145295 0.220943423490389 PTGS2/NFE2L2 2 GO:0016048 detection of temperature stimulus 2/380 24/18722 0.0846218944145295 0.220943423490389 ARRB2/CXCR4 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/380 24/18722 0.0846218944145295 0.220943423490389 TMSB4X/STAT3 2 GO:0036010 protein localization to endosome 2/380 24/18722 0.0846218944145295 0.220943423490389 SORL1/MSN 2 GO:0038095 Fc-epsilon receptor signaling pathway 2/380 24/18722 0.0846218944145295 0.220943423490389 FCER1G/LYN 2 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 2/380 24/18722 0.0846218944145295 0.220943423490389 SEC14L1/USP15 2 GO:0044321 response to leptin 2/380 24/18722 0.0846218944145295 0.220943423490389 PTEN/STAT3 2 GO:0045649 regulation of macrophage differentiation 2/380 24/18722 0.0846218944145295 0.220943423490389 TRIB1/HCLS1 2 GO:0050687 negative regulation of defense response to virus 2/380 24/18722 0.0846218944145295 0.220943423490389 SEC14L1/FGL2 2 GO:0060561 apoptotic process involved in morphogenesis 2/380 24/18722 0.0846218944145295 0.220943423490389 SPI1/TNFRSF1B 2 GO:0070841 inclusion body assembly 2/380 24/18722 0.0846218944145295 0.220943423490389 SORL1/HSPA1A 2 GO:0071378 cellular response to growth hormone stimulus 2/380 24/18722 0.0846218944145295 0.220943423490389 LYN/STAT3 2 GO:0090343 positive regulation of cell aging 2/380 24/18722 0.0846218944145295 0.220943423490389 B2M/YPEL3 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/380 24/18722 0.0846218944145295 0.220943423490389 TMSB4X/STAT3 2 GO:1901984 negative regulation of protein acetylation 2/380 24/18722 0.0846218944145295 0.220943423490389 SPI1/TAF7 2 GO:0006636 unsaturated fatty acid biosynthetic process 3/380 51/18722 0.0847254119830912 0.220943423490389 PTGS2/ELOVL5/IL1B 3 GO:0010656 negative regulation of muscle cell apoptotic process 3/380 51/18722 0.0847254119830912 0.220943423490389 ARRB2/CFLAR/NFE2L2 3 GO:0045661 regulation of myoblast differentiation 3/380 51/18722 0.0847254119830912 0.220943423490389 ZFP36L1/BTG1/FLOT2 3 GO:0060043 regulation of cardiac muscle cell proliferation 3/380 51/18722 0.0847254119830912 0.220943423490389 PTEN/TGFBR2/MAPK1 3 GO:0001655 urogenital system development 11/380 338/18722 0.0848568499327091 0.22115000582463 CXCR2/LRRK2/BASP1/IL6R/PECAM1/CFLAR/PTEN/IQGAP1/EGR1/MME/CAT 11 GO:0051209 release of sequestered calcium ion into cytosol 5/380 115/18722 0.0851218635644555 0.221567973076502 PTPRC/LYN/CORO1A/CYBA/PTPN6 5 GO:1901989 positive regulation of cell cycle phase transition 5/380 115/18722 0.0851218635644555 0.221567973076502 AIF1/DDX3X/CUL3/VPS4B/TMOD3 5 GO:0002312 B cell activation involved in immune response 4/380 82/18722 0.085497637488728 0.222136499855683 PTPRC/BCL6/SPI1/NBN 4 GO:0007032 endosome organization 4/380 82/18722 0.085497637488728 0.222136499855683 SNX10/RAB27A/VPS4B/RAB7A 4 GO:0046889 positive regulation of lipid biosynthetic process 4/380 82/18722 0.085497637488728 0.222136499855683 PTGS2/ELOVL5/IL1B/LPGAT1 4 GO:0033559 unsaturated fatty acid metabolic process 5/380 116/18722 0.0875599809735417 0.227216004548376 PTGS2/CYP4F3/ELOVL5/ALOX5/IL1B 5 GO:0051283 negative regulation of sequestering of calcium ion 5/380 116/18722 0.0875599809735417 0.227216004548376 PTPRC/LYN/CORO1A/CYBA/PTPN6 5 GO:0043367 CD4-positive, alpha-beta T cell differentiation 4/380 83/18722 0.0884662033009163 0.229414973255083 BCL6/IL6R/NFKBIZ/STAT3 4 GO:0010718 positive regulation of epithelial to mesenchymal transition 3/380 52/18722 0.0886240605065681 0.229414973255083 IL1B/SDCBP/TGFBR2 3 GO:0030514 negative regulation of BMP signaling pathway 3/380 52/18722 0.0886240605065681 0.229414973255083 SORL1/UBE2D1/UBE2D3 3 GO:2000378 negative regulation of reactive oxygen species metabolic process 3/380 52/18722 0.0886240605065681 0.229414973255083 CFLAR/STAT3/HIF1A 3 GO:0016485 protein processing 8/380 225/18722 0.0888013813989788 0.229733567638775 SRGN/LRRK2/CTSS/PYCARD/IFI16/CARD16/MYH9/MME 8 GO:0072001 renal system development 10/380 302/18722 0.0892735922311216 0.230814202136019 CXCR2/LRRK2/BASP1/IL6R/PECAM1/CFLAR/IQGAP1/EGR1/MME/CAT 10 GO:0016573 histone acetylation 6/380 152/18722 0.0898134777182189 0.231481516302471 SPI1/IL1B/MSL1/NCOA1/TAF7/PHF20L1 6 GO:0030509 BMP signaling pathway 6/380 152/18722 0.0898134777182189 0.231481516302471 SORL1/EGR1/UBE2D1/USP15/UBE2D3/DDX5 6 GO:1903828 negative regulation of cellular protein localization 5/380 117/18722 0.0900342792722214 0.231481516302471 LRRK2/SPI1/PPP2R5A/NUMB/PICALM 5 GO:0006816 calcium ion transport 13/380 422/18722 0.0903090481590755 0.231481516302471 PTGS2/PTPRC/LYN/CORO1A/PRKCB/CYBA/ARRB2/TSPO/LILRB2/CXCR4/VMP1/PTPN6/PPP3CA 13 GO:0006658 phosphatidylserine metabolic process 2/380 25/18722 0.0907888544459042 0.231481516302471 OSBPL8/PLSCR1 2 GO:0010447 response to acidic pH 2/380 25/18722 0.0907888544459042 0.231481516302471 CTSS/GPR65 2 GO:0032878 regulation of establishment or maintenance of cell polarity 2/380 25/18722 0.0907888544459042 0.231481516302471 RICTOR/FLOT2 2 GO:0035336 long-chain fatty-acyl-CoA metabolic process 2/380 25/18722 0.0907888544459042 0.231481516302471 ACSL1/ELOVL5 2 GO:0046949 fatty-acyl-CoA biosynthetic process 2/380 25/18722 0.0907888544459042 0.231481516302471 ACSL1/ELOVL5 2 GO:0048143 astrocyte activation 2/380 25/18722 0.0907888544459042 0.231481516302471 C5AR1/FPR2 2 GO:0050951 sensory perception of temperature stimulus 2/380 25/18722 0.0907888544459042 0.231481516302471 ARRB2/CXCR4 2 GO:0060074 synapse maturation 2/380 25/18722 0.0907888544459042 0.231481516302471 PTEN/YWHAZ 2 GO:0062009 secondary palate development 2/380 25/18722 0.0907888544459042 0.231481516302471 MMP25/TGFBR2 2 GO:0062149 detection of stimulus involved in sensory perception of pain 2/380 25/18722 0.0907888544459042 0.231481516302471 ARRB2/CXCR4 2 GO:0071450 cellular response to oxygen radical 2/380 25/18722 0.0907888544459042 0.231481516302471 SOD2/NFE2L2 2 GO:0071451 cellular response to superoxide 2/380 25/18722 0.0907888544459042 0.231481516302471 SOD2/NFE2L2 2 GO:0090169 regulation of spindle assembly 2/380 25/18722 0.0907888544459042 0.231481516302471 HSPA1A/VPS4B 2 GO:0090312 positive regulation of protein deacetylation 2/380 25/18722 0.0907888544459042 0.231481516302471 LRRK2/BCL6 2 GO:0090382 phagosome maturation 2/380 25/18722 0.0907888544459042 0.231481516302471 CORO1A/RAB7A 2 GO:1902993 positive regulation of amyloid precursor protein catabolic process 2/380 25/18722 0.0907888544459042 0.231481516302471 LYN/PICALM 2 GO:1904385 cellular response to angiotensin 2/380 25/18722 0.0907888544459042 0.231481516302471 CYBA/NFE2L2 2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 2/380 25/18722 0.0907888544459042 0.231481516302471 ALOX5/ITGB2 2 GO:2000316 regulation of T-helper 17 type immune response 2/380 25/18722 0.0907888544459042 0.231481516302471 CLEC7A/NFKBIZ 2 GO:0046578 regulation of Ras protein signal transduction 7/380 189/18722 0.0911335638972925 0.232220603552969 BCL6/DENND3/ARHGDIB/CYTH4/GPR65/CDC42SE1/CUL3 7 GO:0010921 regulation of phosphatase activity 4/380 84/18722 0.0914839605213438 0.232833276927819 PTPRC/PLEK/BOD1L1/PPP1R15A 4 GO:0061157 mRNA destabilization 4/380 84/18722 0.0914839605213438 0.232833276927819 ZFP36/BTG2/ZFP36L1/ZFP36L2 4 GO:0090287 regulation of cellular response to growth factor stimulus 10/380 304/18722 0.0922461093537031 0.234570953170889 SORL1/LRG1/PRKCB/IL1B/CFLAR/SDCBP/UBE2D1/UBE2D3/HIF1A/HSPA1A 10 GO:0045137 development of primary sexual characteristics 8/380 227/18722 0.0922774989333413 0.234570953170889 BASP1/CEBPB/ARRB2/TNFSF10/NCOA1/KDM5A/SF1/NCOA4 8 GO:0007613 memory 5/380 118/18722 0.0925445263436084 0.234818783624074 PTGS2/CEBPB/PTEN/PJA2/NQO2 5 GO:0022612 gland morphogenesis 5/380 118/18722 0.0925445263436084 0.234818783624074 CEBPB/CFLAR/MSN/TGFBR2/CUL3 5 GO:0051282 regulation of sequestering of calcium ion 5/380 118/18722 0.0925445263436084 0.234818783624074 PTPRC/LYN/CORO1A/CYBA/PTPN6 5 GO:0099172 presynapse organization 3/380 53/18722 0.0925967812638024 0.234818783624074 C5AR1/PTEN/SDCBP 3 GO:0042692 muscle cell differentiation 12/380 384/18722 0.0932340887063833 0.236293456416238 SOD2/RGS2/KDM6B/ARRB2/CFLAR/CD53/PRKAR1A/ACTN1/MYH9/PPP3CA/PAK1/TMOD3 12 GO:0032092 positive regulation of protein binding 4/380 85/18722 0.0945503519758083 0.239120702608089 LRRK2/B2M/STK4/RALB 4 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 4/380 85/18722 0.0945503519758083 0.239120702608089 LYN/OSM/IL6R/HCLS1 4 GO:0097194 execution phase of apoptosis 4/380 85/18722 0.0945503519758083 0.239120702608089 CFLAR/PLSCR1/DICER1/PAK2 4 GO:0045786 negative regulation of cell cycle 12/380 385/18722 0.094575484502609 0.239120702608089 PTGS2/BCL6/DUSP1/CDKN2D/NABP1/BTG2/PTEN/ZFP36L1/ZFP36L2/PRKAR1A/BTG1/NBN 12 GO:0050821 protein stabilization 7/380 191/18722 0.095030146891366 0.240126892652109 TYROBP/RASSF2/PTEN/STK4/UBE2B/HSPA1A/FLOT2 7 GO:0030834 regulation of actin filament depolymerization 3/380 54/18722 0.0966419241806438 0.242707244690383 PLEK/CAPZA1/TMOD3 3 GO:0035065 regulation of histone acetylation 3/380 54/18722 0.0966419241806438 0.242707244690383 SPI1/IL1B/TAF7 3 GO:0001894 tissue homeostasis 9/380 268/18722 0.0968906889483145 0.242707244690383 PTGS2/RAC2/B2M/CORO1A/ACTB/MBP/SNX10/PECAM1/LYZ 9 GO:0050708 regulation of protein secretion 9/380 268/18722 0.0968906889483145 0.242707244690383 HCAR2/ALOX5/MIDN/IL1B/GLUL/RAB11FIP1/NADK/HIF1A/PPP3CA 9 GO:0001963 synaptic transmission, dopaminergic 2/380 26/18722 0.0970828978761533 0.242707244690383 PTGS2/ARRB2 2 GO:0009164 nucleoside catabolic process 2/380 26/18722 0.0970828978761533 0.242707244690383 CDA/APOBEC3A 2 GO:0032515 negative regulation of phosphoprotein phosphatase activity 2/380 26/18722 0.0970828978761533 0.242707244690383 BOD1L1/PPP1R15A 2 GO:0033598 mammary gland epithelial cell proliferation 2/380 26/18722 0.0970828978761533 0.242707244690383 CEBPB/MAPK1 2 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 2/380 26/18722 0.0970828978761533 0.242707244690383 AGTPBP1/HIF1A 2 GO:0043501 skeletal muscle adaptation 2/380 26/18722 0.0970828978761533 0.242707244690383 CFLAR/PPP3CA 2 GO:0045672 positive regulation of osteoclast differentiation 2/380 26/18722 0.0970828978761533 0.242707244690383 TYROBP/FOS 2 GO:0047497 mitochondrion transport along microtubule 2/380 26/18722 0.0970828978761533 0.242707244690383 AGTPBP1/HIF1A 2 GO:0060352 cell adhesion molecule production 2/380 26/18722 0.0970828978761533 0.242707244690383 CXCL8/IL1B 2 GO:0060544 regulation of necroptotic process 2/380 26/18722 0.0970828978761533 0.242707244690383 PELI1/CFLAR 2 GO:0060669 embryonic placenta morphogenesis 2/380 26/18722 0.0970828978761533 0.242707244690383 ZFP36L1/NCOA1 2 GO:1904353 regulation of telomere capping 2/380 26/18722 0.0970828978761533 0.242707244690383 MAPK1/NBN 2 GO:1905523 positive regulation of macrophage migration 2/380 26/18722 0.0970828978761533 0.242707244690383 C5AR1/MAPK1 2 GO:2000108 positive regulation of leukocyte apoptotic process 2/380 26/18722 0.0970828978761533 0.242707244690383 LYN/HCAR2 2 GO:0006140 regulation of nucleotide metabolic process 4/380 86/18722 0.0976648009540068 0.243748027516663 CDA/TMSB4X/STAT3/HIF1A 4 GO:0060761 negative regulation of response to cytokine stimulus 4/380 86/18722 0.0976648009540068 0.243748027516663 PTPRC/IRAK3/CARD16/ADAR 4 GO:0051897 positive regulation of protein kinase B signaling 5/380 120/18722 0.0976718778502424 0.243748027516663 OSM/ARRB2/OSBPL8/HCLS1/RICTOR 5 GO:0001935 endothelial cell proliferation 7/380 193/18722 0.0990180581198617 0.246962000081045 PROK2/LRG1/ALOX5/CYBA/STAT3/RICTOR/HIF1A 7 GO:0045931 positive regulation of mitotic cell cycle 5/380 121/18722 0.100288458373633 0.249983296770063 AIF1/DDX3X/CUL3/VPS4B/TMOD3 5 GO:0031113 regulation of microtubule polymerization 3/380 55/18722 0.100757815927695 0.250293742915691 NIN/HSPA1A/PAK1 3 GO:0044091 membrane biogenesis 3/380 55/18722 0.100757815927695 0.250293742915691 PTEN/PICALM/FLOT2 3 GO:1905517 macrophage migration 3/380 55/18722 0.100757815927695 0.250293742915691 C5AR1/CKLF/MAPK1 3 GO:0051262 protein tetramerization 4/380 87/18722 0.100826712022236 0.250293742915691 SOD2/B2M/STK4/VASP 4 GO:0061014 positive regulation of mRNA catabolic process 4/380 87/18722 0.100826712022236 0.250293742915691 ZFP36/BTG2/ZFP36L1/ZFP36L2 4 GO:1903578 regulation of ATP metabolic process 4/380 87/18722 0.100826712022236 0.250293742915691 TMSB4X/TSPO/STAT3/HIF1A 4 GO:2000177 regulation of neural precursor cell proliferation 4/380 87/18722 0.100826712022236 0.250293742915691 LRRK2/LYN/BTG2/HIF1A 4 GO:0006402 mRNA catabolic process 8/380 232/18722 0.101305494953717 0.251334956724657 ZFP36/SLC11A1/VIM/BTG2/ZFP36L1/ZFP36L2/DDX5/HSPA1A 8 GO:0051208 sequestering of calcium ion 5/380 122/18722 0.10293994039162 0.254386000042951 PTPRC/LYN/CORO1A/CYBA/PTPN6 5 GO:0018393 internal peptidyl-lysine acetylation 6/380 158/18722 0.103211701034731 0.254386000042951 SPI1/IL1B/MSL1/NCOA1/TAF7/PHF20L1 6 GO:0043488 regulation of mRNA stability 6/380 158/18722 0.103211701034731 0.254386000042951 ZFP36/SLC11A1/VIM/BTG2/ZFP36L1/ZFP36L2 6 GO:0002719 negative regulation of cytokine production involved in immune response 2/380 27/18722 0.103496358459033 0.254386000042951 BCL6/IRAK3 2 GO:0002825 regulation of T-helper 1 type immune response 2/380 27/18722 0.103496358459033 0.254386000042951 SLC11A1/IL1B 2 GO:0007628 adult walking behavior 2/380 27/18722 0.103496358459033 0.254386000042951 ARRB2/AGTPBP1 2 GO:0010758 regulation of macrophage chemotaxis 2/380 27/18722 0.103496358459033 0.254386000042951 C5AR1/MAPK1 2 GO:0018904 ether metabolic process 2/380 27/18722 0.103496358459033 0.254386000042951 ALOX5/LPCAT2 2 GO:0032967 positive regulation of collagen biosynthetic process 2/380 27/18722 0.103496358459033 0.254386000042951 VIM/ARRB2 2 GO:0034143 regulation of toll-like receptor 4 signaling pathway 2/380 27/18722 0.103496358459033 0.254386000042951 LYN/PELI1 2 GO:0034453 microtubule anchoring 2/380 27/18722 0.103496358459033 0.254386000042951 NIN/CEP350 2 GO:0039529 RIG-I signaling pathway 2/380 27/18722 0.103496358459033 0.254386000042951 SEC14L1/USP15 2 GO:1902883 negative regulation of response to oxidative stress 2/380 27/18722 0.103496358459033 0.254386000042951 LRRK2/NFE2L2 2 GO:1902914 regulation of protein polyubiquitination 2/380 27/18722 0.103496358459033 0.254386000042951 UBE2D1/DDX3X 2 GO:1903203 regulation of oxidative stress-induced neuron death 2/380 27/18722 0.103496358459033 0.254386000042951 MCL1/HIF1A 2 GO:1903205 regulation of hydrogen peroxide-induced cell death 2/380 27/18722 0.103496358459033 0.254386000042951 LRRK2/NFE2L2 2 GO:0007260 tyrosine phosphorylation of STAT protein 4/380 88/18722 0.104035471828378 0.255562774474003 LYN/OSM/IL6R/HCLS1 4 GO:0002090 regulation of receptor internalization 3/380 56/18722 0.104942762729129 0.256749046884958 ARRB2/SDCBP/NUMB 3 GO:0010332 response to gamma radiation 3/380 56/18722 0.104942762729129 0.256749046884958 PTPRC/CYBA/EGR1 3 GO:0022029 telencephalon cell migration 3/380 56/18722 0.104942762729129 0.256749046884958 LRRK2/MBOAT7/CXCR4 3 GO:0032608 interferon-beta production 3/380 56/18722 0.104942762729129 0.256749046884958 PYCARD/IRF1/DDX3X 3 GO:0032648 regulation of interferon-beta production 3/380 56/18722 0.104942762729129 0.256749046884958 PYCARD/IRF1/DDX3X 3 GO:0051653 spindle localization 3/380 56/18722 0.104942762729129 0.256749046884958 ACTR2/ACTR3/MYH9 3 GO:0070534 protein K63-linked ubiquitination 3/380 56/18722 0.104942762729129 0.256749046884958 PELI1/UBE2B/DDX3X 3 GO:0006690 icosanoid metabolic process 5/380 123/18722 0.105626033745407 0.25812247715626 PTGS2/CYP4F3/ALOX5AP/ALOX5/IL1B 5 GO:0010811 positive regulation of cell-substrate adhesion 5/380 123/18722 0.105626033745407 0.25812247715626 PREX1/MYADM/IQGAP1/STK4/DOCK5 5 GO:0045787 positive regulation of cell cycle 10/380 313/18722 0.106345819007134 0.259731570643145 AIF1/IL1B/CCPG1/PLSCR1/UBE2B/DDX3X/CUL3/VPS4B/PHIP/TMOD3 10 GO:0051781 positive regulation of cell division 4/380 89/18722 0.107290449898552 0.261887639954104 OSM/IL1B/CUL3/CAT 4 GO:0006475 internal protein amino acid acetylation 6/380 160/18722 0.107898050447928 0.263219034358856 SPI1/IL1B/MSL1/NCOA1/TAF7/PHF20L1 6 GO:0060249 anatomical structure homeostasis 10/380 314/18722 0.107985161006145 0.263279883051826 PTGS2/RAC2/B2M/CORO1A/ACTB/MBP/SNX10/PECAM1/LYZ/HIF1A 10 GO:0048738 cardiac muscle tissue development 8/380 236/18722 0.108872186049113 0.264857416747478 RGS2/KDM6B/ARRB2/PTEN/PRKAR1A/TGFBR2/PAK1/MAPK1 8 GO:0048762 mesenchymal cell differentiation 8/380 236/18722 0.108872186049113 0.264857416747478 S100A4/IL1B/PTEN/SDCBP/TGFBR2/HIF1A/DDX5/MAPK1 8 GO:0006611 protein export from nucleus 3/380 57/18722 0.109195053043943 0.264857416747478 IL1B/XPO6/NUP214 3 GO:0016447 somatic recombination of immunoglobulin gene segments 3/380 57/18722 0.109195053043943 0.264857416747478 PTPRC/BCL6/NBN 3 GO:0034205 amyloid-beta formation 3/380 57/18722 0.109195053043943 0.264857416747478 SORL1/RTN3/PICALM 3 GO:0051289 protein homotetramerization 3/380 57/18722 0.109195053043943 0.264857416747478 SOD2/B2M/VASP 3 GO:0061756 leukocyte adhesion to vascular endothelial cell 3/380 57/18722 0.109195053043943 0.264857416747478 SELL/ALOX5/ITGB2 3 GO:0097120 receptor localization to synapse 3/380 57/18722 0.109195053043943 0.264857416747478 TYROBP/STX3/STX7 3 GO:1900024 regulation of substrate adhesion-dependent cell spreading 3/380 57/18722 0.109195053043943 0.264857416747478 PREX1/MYADM/DOCK5 3 GO:0048167 regulation of synaptic plasticity 7/380 198/18722 0.109383135982561 0.265161752081364 PTGS2/TYROBP/LILRB2/PTEN/STX3/MME/MAPK1 7 GO:0000303 response to superoxide 2/380 28/18722 0.110021827326497 0.265645632113863 SOD2/NFE2L2 2 GO:0010714 positive regulation of collagen metabolic process 2/380 28/18722 0.110021827326497 0.265645632113863 VIM/ARRB2 2 GO:0019098 reproductive behavior 2/380 28/18722 0.110021827326497 0.265645632113863 PTEN/NCOA1 2 GO:0032801 receptor catabolic process 2/380 28/18722 0.110021827326497 0.265645632113863 LAPTM5/SH3GLB1 2 GO:0080111 DNA demethylation 2/380 28/18722 0.110021827326497 0.265645632113863 APOBEC3A/TET2 2 GO:0090659 walking behavior 2/380 28/18722 0.110021827326497 0.265645632113863 ARRB2/AGTPBP1 2 GO:1903671 negative regulation of sprouting angiogenesis 2/380 28/18722 0.110021827326497 0.265645632113863 KLF2/ALOX5 2 GO:0030901 midbrain development 4/380 90/18722 0.110590999424848 0.266412333654284 CXCR2/BASP1/ACTB/MBP 4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 4/380 90/18722 0.110590999424848 0.266412333654284 LRRK2/TRIB1/HSPA1A/NFE2L2 4 GO:0034644 cellular response to UV 4/380 90/18722 0.110590999424848 0.266412333654284 PTGS2/CARD16/MME/N4BP1 4 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 4/380 90/18722 0.110590999424848 0.266412333654284 SOD2/PTEN/NQO2/PAK1 4 GO:0034250 positive regulation of cellular amide metabolic process 6/380 162/18722 0.112692421518614 0.271320298539698 VIM/PICALM/DDX3X/PPP1R15A/MAPK1/NFE2L2 6 GO:0051259 protein complex oligomerization 8/380 238/18722 0.11276902353337 0.27135046287717 SOD2/STEAP4/ALOX5AP/B2M/STK4/PYCARD/VASP/RNF213 8 GO:0002931 response to ischemia 3/380 58/18722 0.113512960124094 0.272521193948717 EGR1/BID/CPEB4 3 GO:0007405 neuroblast proliferation 3/380 58/18722 0.113512960124094 0.272521193948717 LRRK2/NUMB/HIF1A 3 GO:0043525 positive regulation of neuron apoptotic process 3/380 58/18722 0.113512960124094 0.272521193948717 TYROBP/MCL1/NQO2 3 GO:0043666 regulation of phosphoprotein phosphatase activity 3/380 58/18722 0.113512960124094 0.272521193948717 PTPRC/BOD1L1/PPP1R15A 3 GO:0099003 vesicle-mediated transport in synapse 7/380 200/18722 0.11368529804126 0.27278030436529 LRRK2/ACTB/PRKCB/PTEN/STX3/NUMB/PICALM 7 GO:0006885 regulation of pH 4/380 91/18722 0.113936458043616 0.272919060981173 LRRK2/SLC11A1/MAPK1/RAB7A 4 GO:0051492 regulation of stress fiber assembly 4/380 91/18722 0.113936458043616 0.272919060981173 WAS/GPR65/PAK2/PAK1 4 GO:1990874 vascular associated smooth muscle cell proliferation 4/380 91/18722 0.113936458043616 0.272919060981173 SOD2/PTEN/NQO2/PAK1 4 GO:0050657 nucleic acid transport 6/380 163/18722 0.11512967057773 0.275310081816311 MX2/ZFP36/ZFP36L1/TGFBR2/NUP214/ZC3H11A 6 GO:0050658 RNA transport 6/380 163/18722 0.11512967057773 0.275310081816311 MX2/ZFP36/ZFP36L1/TGFBR2/NUP214/ZC3H11A 6 GO:0072331 signal transduction by p53 class mediator 6/380 163/18722 0.11512967057773 0.275310081816311 PYCARD/IFI16/CD44/USP10/DDX5/NBN 6 GO:0051052 regulation of DNA metabolic process 11/380 359/18722 0.115785268062651 0.275973375056974 PTPRC/BCL6/DUSP1/SPI1/SMCHD1/WAS/ARRB2/ACTR2/UBE2B/MAPK1/NBN 11 GO:2000146 negative regulation of cell motility 11/380 359/18722 0.115785268062651 0.275973375056974 IFITM1/AIF1/DUSP1/TRIB1/WAS/ARHGDIB/CNN2/PTEN/OSBPL8/STAT3/NFE2L2 11 GO:0006473 protein acetylation 7/380 201/18722 0.11586940882807 0.275973375056974 SPI1/IL1B/MSL1/NCOA1/DDX3X/TAF7/PHF20L1 7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 2/380 29/18722 0.116652145744649 0.275973375056974 ZFP36/BTG2 2 GO:0000305 response to oxygen radical 2/380 29/18722 0.116652145744649 0.275973375056974 SOD2/NFE2L2 2 GO:0002360 T cell lineage commitment 2/380 29/18722 0.116652145744649 0.275973375056974 IL6R/STAT3 2 GO:0010955 negative regulation of protein processing 2/380 29/18722 0.116652145744649 0.275973375056974 LRRK2/CARD16 2 GO:0019359 nicotinamide nucleotide biosynthetic process 2/380 29/18722 0.116652145744649 0.275973375056974 NAMPT/NADK 2 GO:0019363 pyridine nucleotide biosynthetic process 2/380 29/18722 0.116652145744649 0.275973375056974 NAMPT/NADK 2 GO:0021591 ventricular system development 2/380 29/18722 0.116652145744649 0.275973375056974 MBOAT7/NUMB 2 GO:0021772 olfactory bulb development 2/380 29/18722 0.116652145744649 0.275973375056974 LRRK2/AGTPBP1 2 GO:0051654 establishment of mitochondrion localization 2/380 29/18722 0.116652145744649 0.275973375056974 AGTPBP1/HIF1A 2 GO:0062098 regulation of programmed necrotic cell death 2/380 29/18722 0.116652145744649 0.275973375056974 PELI1/CFLAR 2 GO:0070979 protein K11-linked ubiquitination 2/380 29/18722 0.116652145744649 0.275973375056974 UBE2D3/UBE2B 2 GO:1902430 negative regulation of amyloid-beta formation 2/380 29/18722 0.116652145744649 0.275973375056974 SORL1/RTN3 2 GO:1903318 negative regulation of protein maturation 2/380 29/18722 0.116652145744649 0.275973375056974 LRRK2/CARD16 2 GO:2000406 positive regulation of T cell migration 2/380 29/18722 0.116652145744649 0.275973375056974 AIF1/PYCARD 2 GO:0006911 phagocytosis, engulfment 5/380 127/18722 0.116710345862347 0.275973375056974 AIF1/RAC2/ITGB2/RHOG/MYH9 5 GO:0030048 actin filament-based movement 5/380 127/18722 0.116710345862347 0.275973375056974 MYO1F/WIPF1/WAS/MYH9/MYL6 5 GO:0051224 negative regulation of protein transport 5/380 127/18722 0.116710345862347 0.275973375056974 LRRK2/MIDN/IL1B/RAB11FIP1/PPP3CA 5 GO:0019369 arachidonic acid metabolic process 3/380 59/18722 0.117894744453871 0.277688677843239 PTGS2/CYP4F3/ALOX5 3 GO:0021885 forebrain cell migration 3/380 59/18722 0.117894744453871 0.277688677843239 LRRK2/MBOAT7/CXCR4 3 GO:0030042 actin filament depolymerization 3/380 59/18722 0.117894744453871 0.277688677843239 PLEK/CAPZA1/TMOD3 3 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 3/380 59/18722 0.117894744453871 0.277688677843239 LYN/FPR2/FGR 3 GO:0046324 regulation of glucose import 3/380 59/18722 0.117894744453871 0.277688677843239 OSBPL8/STXBP3/NFE2L2 3 GO:0051353 positive regulation of oxidoreductase activity 3/380 59/18722 0.117894744453871 0.277688677843239 CYBA/IL1B/HIF1A 3 GO:0090303 positive regulation of wound healing 3/380 59/18722 0.117894744453871 0.277688677843239 CXCR4/CLEC7A/NFE2L2 3 GO:0021700 developmental maturation 9/380 280/18722 0.118026743760831 0.277845058269661 LRRK2/KLF2/SNX10/PTEN/CLEC7A/PTBP3/PICALM/YWHAZ/HIF1A 9 GO:0009416 response to light stimulus 10/380 320/18722 0.118123538214738 0.277918435744121 PTGS2/DUSP1/FOS/CDKN2D/CARD16/UBE2B/HIF1A/MME/CAT/N4BP1 10 GO:0022411 cellular component disassembly 13/380 443/18722 0.118743801249564 0.279222653132649 LCP1/CTSS/PLEK/PRKCB/IRAK3/TSPO/VMP1/BNIP3L/CAPZA1/HIF1A/DICER1/VPS4B/TMOD3 13 GO:0006639 acylglycerol metabolic process 5/380 128/18722 0.119564775972991 0.28099712888214 SORL1/ACSL1/MBOAT7/LPGAT1/CAT 5 GO:0071772 response to BMP 6/380 165/18722 0.120083348310806 0.281902982315002 SORL1/EGR1/UBE2D1/USP15/UBE2D3/DDX5 6 GO:0071773 cellular response to BMP stimulus 6/380 165/18722 0.120083348310806 0.281902982315002 SORL1/EGR1/UBE2D1/USP15/UBE2D3/DDX5 6 GO:0060541 respiratory system development 7/380 203/18722 0.120303097997935 0.282262393363577 BASP1/SMCHD1/KLF2/TGFBR2/YWHAZ/MME/MAPK1 7 GO:0019217 regulation of fatty acid metabolic process 4/380 93/18722 0.120759379925 0.282706453279367 PTGS2/ELOVL5/IL1B/LPGAT1 4 GO:0045185 maintenance of protein location 4/380 93/18722 0.120759379925 0.282706453279367 SRGN/SORL1/TMSB4X/TSPO 4 GO:0051591 response to cAMP 4/380 93/18722 0.120759379925 0.282706453279367 AQP9/DUSP1/FOS/ZFP36L1 4 GO:0097306 cellular response to alcohol 4/380 93/18722 0.120759379925 0.282706453279367 SOD2/SPI1/KLF2/PTEN 4 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 3/380 60/18722 0.122338656074673 0.28603619781663 SEC14L1/USP15/HSPA1A 3 GO:0042306 regulation of protein import into nucleus 3/380 60/18722 0.122338656074673 0.28603619781663 PTGS2/HCLS1/MAPK1 3 GO:0006022 aminoglycan metabolic process 5/380 129/18722 0.122451859891747 0.28603619781663 PGLYRP1/IL1B/IDS/CD44/CTBS 5 GO:0006638 neutral lipid metabolic process 5/380 129/18722 0.122451859891747 0.28603619781663 SORL1/ACSL1/MBOAT7/LPGAT1/CAT 5 GO:0051236 establishment of RNA localization 6/380 166/18722 0.122599378634912 0.286065216814794 MX2/ZFP36/ZFP36L1/TGFBR2/NUP214/ZC3H11A 6 GO:0061013 regulation of mRNA catabolic process 6/380 166/18722 0.122599378634912 0.286065216814794 ZFP36/SLC11A1/VIM/BTG2/ZFP36L1/ZFP36L2 6 GO:0033137 negative regulation of peptidyl-serine phosphorylation 2/380 30/18722 0.123380398056487 0.286153332841853 RASSF2/PTEN 2 GO:0045070 positive regulation of viral genome replication 2/380 30/18722 0.123380398056487 0.286153332841853 DDX3X/ADAR 2 GO:0045948 positive regulation of translational initiation 2/380 30/18722 0.123380398056487 0.286153332841853 DDX3X/PPP1R15A 2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 2/380 30/18722 0.123380398056487 0.286153332841853 LAPTM5/PTPN6 2 GO:0051968 positive regulation of synaptic transmission, glutamatergic 2/380 30/18722 0.123380398056487 0.286153332841853 PTGS2/GLUL 2 GO:0060218 hematopoietic stem cell differentiation 2/380 30/18722 0.123380398056487 0.286153332841853 OSM/NFE2L2 2 GO:0060292 long-term synaptic depression 2/380 30/18722 0.123380398056487 0.286153332841853 LILRB2/PTEN 2 GO:0060674 placenta blood vessel development 2/380 30/18722 0.123380398056487 0.286153332841853 JUNB/MAPK1 2 GO:0070168 negative regulation of biomineral tissue development 2/380 30/18722 0.123380398056487 0.286153332841853 SRGN/HIF1A 2 GO:0090314 positive regulation of protein targeting to membrane 2/380 30/18722 0.123380398056487 0.286153332841853 ITGB2/PAK1 2 GO:1903579 negative regulation of ATP metabolic process 2/380 30/18722 0.123380398056487 0.286153332841853 TSPO/STAT3 2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 4/380 94/18722 0.124235447544429 0.287978719403754 ACTB/CDKN2D/PTEN/CCNL1 4 GO:0051028 mRNA transport 5/380 130/18722 0.125371237908556 0.290452512331911 MX2/ZFP36/ZFP36L1/NUP214/ZC3H11A 5 GO:0010959 regulation of metal ion transport 12/380 406/18722 0.125443234527293 0.290460414556088 PTGS2/LYN/B2M/CORO1A/CYBA/ARRB2/TSPO/LILRB2/PTEN/CXCR4/VMP1/PTPN6 12 GO:0006900 vesicle budding from membrane 3/380 61/18722 0.126842936799271 0.292900674670072 PICALM/CUL3/RAB7A 3 GO:0043030 regulation of macrophage activation 3/380 61/18722 0.126842936799271 0.292900674670072 PTPRC/LRRK2/PJA2 3 GO:0050994 regulation of lipid catabolic process 3/380 61/18722 0.126842936799271 0.292900674670072 SORL1/HCAR2/IL1B 3 GO:0060997 dendritic spine morphogenesis 3/380 61/18722 0.126842936799271 0.292900674670072 LRRK2/PTEN/ACTR2 3 GO:2000401 regulation of lymphocyte migration 3/380 61/18722 0.126842936799271 0.292900674670072 AIF1/MSN/PYCARD 3 GO:0017148 negative regulation of translation 8/380 245/18722 0.126993771588809 0.293089167672264 RGS2/ZFP36/BTG2/ZFP36L1/ZFP36L2/STAT3/DDX3X/CPEB4 8 GO:0048863 stem cell differentiation 7/380 206/18722 0.127115389612384 0.293210062640766 PTPRC/OSM/ZFP36L2/STAT3/HIF1A/MAPK1/NFE2L2 7 GO:1902806 regulation of cell cycle G1/S phase transition 6/380 168/18722 0.127708779388639 0.29420154535554 AIF1/CDKN2D/PTEN/BID/DDX3X/PTPN6 6 GO:2000241 regulation of reproductive process 6/380 168/18722 0.127708779388639 0.29420154535554 DUSP1/ARHGDIB/STK4/PRKAR1A/UBE2B/MYH9 6 GO:0048709 oligodendrocyte differentiation 4/380 95/18722 0.127753634453091 0.29420154535554 LYN/PTEN/CXCR4/TNFRSF1B 4 GO:1904950 negative regulation of establishment of protein localization 5/380 131/18722 0.128322541512934 0.295351067014823 LRRK2/MIDN/IL1B/RAB11FIP1/PPP3CA 5 GO:0001516 prostaglandin biosynthetic process 2/380 31/18722 0.130199904806876 0.296768889589409 PTGS2/IL1B 2 GO:0006301 postreplication repair 2/380 31/18722 0.130199904806876 0.296768889589409 UBE2B/USP10 2 GO:0008045 motor neuron axon guidance 2/380 31/18722 0.130199904806876 0.296768889589409 RAC2/RHOG 2 GO:0021988 olfactory lobe development 2/380 31/18722 0.130199904806876 0.296768889589409 LRRK2/AGTPBP1 2 GO:0030212 hyaluronan metabolic process 2/380 31/18722 0.130199904806876 0.296768889589409 IL1B/CD44 2 GO:0034656 nucleobase-containing small molecule catabolic process 2/380 31/18722 0.130199904806876 0.296768889589409 CDA/APOBEC3A 2 GO:0035510 DNA dealkylation 2/380 31/18722 0.130199904806876 0.296768889589409 APOBEC3A/TET2 2 GO:0036257 multivesicular body organization 2/380 31/18722 0.130199904806876 0.296768889589409 RAB27A/VPS4B 2 GO:0036474 cell death in response to hydrogen peroxide 2/380 31/18722 0.130199904806876 0.296768889589409 LRRK2/NFE2L2 2 GO:0036475 neuron death in response to oxidative stress 2/380 31/18722 0.130199904806876 0.296768889589409 MCL1/HIF1A 2 GO:0045987 positive regulation of smooth muscle contraction 2/380 31/18722 0.130199904806876 0.296768889589409 PTGS2/PROK2 2 GO:0046457 prostanoid biosynthetic process 2/380 31/18722 0.130199904806876 0.296768889589409 PTGS2/IL1B 2 GO:0060055 angiogenesis involved in wound healing 2/380 31/18722 0.130199904806876 0.296768889589409 ALOX5/CXCR4 2 GO:0070528 protein kinase C signaling 2/380 31/18722 0.130199904806876 0.296768889589409 PLEK/MYADM 2 GO:0071480 cellular response to gamma radiation 2/380 31/18722 0.130199904806876 0.296768889589409 CYBA/EGR1 2 GO:0097106 postsynaptic density organization 2/380 31/18722 0.130199904806876 0.296768889589409 LILRB2/PTEN 2 GO:0110150 negative regulation of biomineralization 2/380 31/18722 0.130199904806876 0.296768889589409 SRGN/HIF1A 2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/380 31/18722 0.130199904806876 0.296768889589409 CFLAR/DDX3X 2 GO:0018394 peptidyl-lysine acetylation 6/380 169/18722 0.130301714456638 0.296841183821335 SPI1/IL1B/MSL1/NCOA1/TAF7/PHF20L1 6 GO:0045667 regulation of osteoblast differentiation 5/380 132/18722 0.131305393678685 0.297914163556242 IFITM1/IL6R/RASSF2/CEBPB/DDX5 5 GO:0010769 regulation of cell morphogenesis involved in differentiation 4/380 96/18722 0.131313211820124 0.297914163556242 PREX1/MYADM/ACTR2/DOCK5 4 GO:1901655 cellular response to ketone 4/380 96/18722 0.131313211820124 0.297914163556242 KLF2/CFLAR/MSN/NCOA4 4 GO:0009116 nucleoside metabolic process 3/380 62/18722 0.131405822319495 0.297914163556242 CDA/APOBEC3A/TYMP 3 GO:0009311 oligosaccharide metabolic process 3/380 62/18722 0.131405822319495 0.297914163556242 MGAM/ST8SIA4/CTBS 3 GO:0019933 cAMP-mediated signaling 3/380 62/18722 0.131405822319495 0.297914163556242 RGS2/CAP1/UBE2B 3 GO:0048488 synaptic vesicle endocytosis 3/380 62/18722 0.131405822319495 0.297914163556242 LRRK2/ACTB/PICALM 3 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 3/380 62/18722 0.131405822319495 0.297914163556242 STX3/NUMB/FLOT2 3 GO:0140238 presynaptic endocytosis 3/380 62/18722 0.131405822319495 0.297914163556242 LRRK2/ACTB/PICALM 3 GO:1903311 regulation of mRNA metabolic process 9/380 288/18722 0.133410567721378 0.302297353825593 ZFP36/SLC11A1/CELF2/VIM/BTG2/ZFP36L1/ZFP36L2/DDX5/SF1 9 GO:0010565 regulation of cellular ketone metabolic process 5/380 133/18722 0.134319409148313 0.304031372390756 PTGS2/ELOVL5/IL1B/LPGAT1/EGR1 5 GO:0046887 positive regulation of hormone secretion 5/380 133/18722 0.134319409148313 0.304031372390756 HCAR2/GLUL/NADK/HIF1A/RAB8B 5 GO:0070167 regulation of biomineral tissue development 4/380 97/18722 0.134913439705439 0.305212829675498 SRGN/ALOX5/CEBPB/HIF1A 4 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 12/380 412/18722 0.135195727012693 0.305688149438738 LRRK2/PELI1/TRIB1/ARRB2/SDCBP/FBXL5/UBE2D3/UBE2B/HSPA1A/CUL3/NFE2L2/N4BP1 12 GO:0030239 myofibril assembly 3/380 63/18722 0.13602554421116 0.306908992932478 CFLAR/PRKAR1A/TMOD3 3 GO:0032233 positive regulation of actin filament bundle assembly 3/380 63/18722 0.13602554421116 0.306908992932478 PLEK/GPR65/PAK1 3 GO:1904589 regulation of protein import 3/380 63/18722 0.13602554421116 0.306908992932478 PTGS2/HCLS1/MAPK1 3 GO:2000756 regulation of peptidyl-lysine acetylation 3/380 63/18722 0.13602554421116 0.306908992932478 SPI1/IL1B/TAF7 3 GO:0008156 negative regulation of DNA replication 2/380 32/18722 0.137104216045291 0.307540442241424 BCL6/S100A11 2 GO:0010039 response to iron ion 2/380 32/18722 0.137104216045291 0.307540442241424 B2M/HIF1A 2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 2/380 32/18722 0.137104216045291 0.307540442241424 CFLAR/NFE2L2 2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 2/380 32/18722 0.137104216045291 0.307540442241424 LRG1/SDCBP 2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 2/380 32/18722 0.137104216045291 0.307540442241424 CDKN2D/PTEN 2 GO:0045761 regulation of adenylate cyclase activity 2/380 32/18722 0.137104216045291 0.307540442241424 P2RY13/CAP1 2 GO:0051497 negative regulation of stress fiber assembly 2/380 32/18722 0.137104216045291 0.307540442241424 WAS/PAK2 2 GO:0072525 pyridine-containing compound biosynthetic process 2/380 32/18722 0.137104216045291 0.307540442241424 NAMPT/NADK 2 GO:1901889 negative regulation of cell junction assembly 2/380 32/18722 0.137104216045291 0.307540442241424 IL1B/PTEN 2 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 2/380 32/18722 0.137104216045291 0.307540442241424 LRG1/SDCBP 2 GO:2000191 regulation of fatty acid transport 2/380 32/18722 0.137104216045291 0.307540442241424 ACSL1/IL1B 2 GO:0008277 regulation of G protein-coupled receptor signaling pathway 5/380 134/18722 0.137364194716917 0.307797547421239 CXCL8/RGS2/RGS18/PLEK/ARRB2 5 GO:0061041 regulation of wound healing 5/380 134/18722 0.137364194716917 0.307797547421239 ALOX5/PTEN/CXCR4/CLEC7A/NFE2L2 5 GO:0070301 cellular response to hydrogen peroxide 4/380 98/18722 0.1385535677602 0.310134439463237 LRRK2/KLF2/KDM6B/NFE2L2 4 GO:1904029 regulation of cyclin-dependent protein kinase activity 4/380 98/18722 0.1385535677602 0.310134439463237 ACTB/CDKN2D/PTEN/CCNL1 4 GO:0042180 cellular ketone metabolic process 7/380 211/18722 0.138891272122751 0.310562057782391 PTGS2/CYP4F3/ELOVL5/IL1B/LPGAT1/EGR1/NQO2 7 GO:0050807 regulation of synapse organization 7/380 211/18722 0.138891272122751 0.310562057782391 SRGN/LRRK2/TUBA1A/LILRB2/PTEN/ACTR2/YWHAZ 7 GO:0016236 macroautophagy 9/380 291/18722 0.139438368649047 0.31162083969853 LRRK2/ATG16L2/VMP1/RALB/BNIP3L/HIF1A/VPS4B/SH3GLB1/RAB7A 9 GO:0001101 response to acid chemical 5/380 135/18722 0.140439349515369 0.313692323416448 LYN/KLF2/CYBA/CEBPB/CPEB4 5 GO:0048857 neural nucleus development 3/380 64/18722 0.140700331839927 0.313944101866222 BASP1/ACTB/MBP 3 GO:0055002 striated muscle cell development 3/380 64/18722 0.140700331839927 0.313944101866222 CFLAR/PRKAR1A/TMOD3 3 GO:0000910 cytokinesis 6/380 173/18722 0.140923001872952 0.314275362260111 ACTR2/ACTR3/MYH9/CUL3/VPS4B/SH3GLB1 6 GO:0061448 connective tissue development 8/380 252/18722 0.142106306122526 0.316031511070211 SORL1/SPI1/IL6R/CFLAR/EGR1/CD44/TGFBR2/HIF1A 8 GO:0090257 regulation of muscle system process 8/380 252/18722 0.142106306122526 0.316031511070211 PTGS2/RGS2/PROK2/AIF1/TNFRSF1B/PPP3CA/PAK1/DOCK5 8 GO:0003300 cardiac muscle hypertrophy 4/380 99/18722 0.142232835914952 0.316031511070211 RGS2/TNFRSF1B/PPP3CA/PAK1 4 GO:0010717 regulation of epithelial to mesenchymal transition 4/380 99/18722 0.142232835914952 0.316031511070211 IL1B/PTEN/SDCBP/TGFBR2 4 GO:0021549 cerebellum development 4/380 99/18722 0.142232835914952 0.316031511070211 AIF1/AGTPBP1/NCOA1/PAK1 4 GO:0060996 dendritic spine development 4/380 99/18722 0.142232835914952 0.316031511070211 LRRK2/PTEN/ACTR2/PAK2 4 GO:0110149 regulation of biomineralization 4/380 99/18722 0.142232835914952 0.316031511070211 SRGN/ALOX5/CEBPB/HIF1A 4 GO:0072073 kidney epithelium development 5/380 136/18722 0.143544465292574 0.317486414587064 CXCR2/BASP1/PECAM1/IQGAP1/CAT 5 GO:0098876 vesicle-mediated transport to the plasma membrane 5/380 136/18722 0.143544465292574 0.317486414587064 SORL1/ACAP2/STX3/CMTM6/RAB7A 5 GO:0099024 plasma membrane invagination 5/380 136/18722 0.143544465292574 0.317486414587064 AIF1/RAC2/ITGB2/RHOG/MYH9 5 GO:1900180 regulation of protein localization to nucleus 5/380 136/18722 0.143544465292574 0.317486414587064 PTGS2/RASSF5/GLUL/HCLS1/MAPK1 5 GO:0001975 response to amphetamine 2/380 33/18722 0.144087104801968 0.317486414587064 RGS2/PPP3CA 2 GO:0018345 protein palmitoylation 2/380 33/18722 0.144087104801968 0.317486414587064 ZDHHC18/GLUL 2 GO:0019362 pyridine nucleotide metabolic process 2/380 33/18722 0.144087104801968 0.317486414587064 NAMPT/NADK 2 GO:0033198 response to ATP 2/380 33/18722 0.144087104801968 0.317486414587064 PTGS2/PTEN 2 GO:0040020 regulation of meiotic nuclear division 2/380 33/18722 0.144087104801968 0.317486414587064 PRKAR1A/UBE2B 2 GO:0046496 nicotinamide nucleotide metabolic process 2/380 33/18722 0.144087104801968 0.317486414587064 NAMPT/NADK 2 GO:0046685 response to arsenic-containing substance 2/380 33/18722 0.144087104801968 0.317486414587064 PTEN/DDX3X 2 GO:0061842 microtubule organizing center localization 2/380 33/18722 0.144087104801968 0.317486414587064 ARPC5/NIN 2 GO:0071539 protein localization to centrosome 2/380 33/18722 0.144087104801968 0.317486414587064 SNX10/CEP350 2 GO:0099084 postsynaptic specialization organization 2/380 33/18722 0.144087104801968 0.317486414587064 LILRB2/PTEN 2 GO:1902692 regulation of neuroblast proliferation 2/380 33/18722 0.144087104801968 0.317486414587064 LRRK2/HIF1A 2 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 2/380 33/18722 0.144087104801968 0.317486414587064 CDKN2D/PTEN 2 GO:0007409 axonogenesis 12/380 418/18722 0.145351821761609 0.319610448374214 PLXNC1/RAC2/ACTB/S100A6/PTEN/NUMB/VASP/PICALM/RHOG/NIN/PAK2/PAK1 12 GO:0048524 positive regulation of viral process 3/380 65/18722 0.145428414171691 0.319610448374214 DDX3X/ADAR/RAB7A 3 GO:0060389 pathway-restricted SMAD protein phosphorylation 3/380 65/18722 0.145428414171691 0.319610448374214 SDCBP/USP15/TGFBR2 3 GO:0070613 regulation of protein processing 3/380 65/18722 0.145428414171691 0.319610448374214 LRRK2/CARD16/MYH9 3 GO:0090307 mitotic spindle assembly 3/380 65/18722 0.145428414171691 0.319610448374214 STAG2/HSPA1A/VPS4B 3 GO:0010948 negative regulation of cell cycle process 9/380 294/18722 0.14560410636339 0.31966479546343 BCL6/DUSP1/CDKN2D/NABP1/PTEN/ZFP36L1/ZFP36L2/PRKAR1A/NBN 9 GO:0051604 protein maturation 9/380 294/18722 0.14560410636339 0.31966479546343 SRGN/SORL1/LRRK2/CTSS/PYCARD/IFI16/CARD16/MYH9/MME 9 GO:0044728 DNA methylation or demethylation 4/380 100/18722 0.145950475055149 0.319762163403289 SPI1/FOS/APOBEC3A/TET2 4 GO:0045807 positive regulation of endocytosis 4/380 100/18722 0.145950475055149 0.319762163403289 LRRK2/B2M/ARRB2/PPP3CA 4 GO:0060079 excitatory postsynaptic potential 4/380 100/18722 0.145950475055149 0.319762163403289 LRRK2/ARRB2/PTEN/PPP3CA 4 GO:0110020 regulation of actomyosin structure organization 4/380 100/18722 0.145950475055149 0.319762163403289 WAS/GPR65/PAK2/PAK1 4 GO:0022900 electron transport chain 6/380 175/18722 0.146379988383592 0.320537358223636 NCF1/STEAP4/NCF2/CYBA/BID/NQO2 6 GO:0030879 mammary gland development 5/380 137/18722 0.146679126696621 0.321026409075033 CEBPB/TGFBR2/NCOA1/HIF1A/MAPK1 5 GO:0010634 positive regulation of epithelial cell migration 6/380 176/18722 0.1491441839458 0.326252902381437 PTGS2/TMSB4X/TGFBR2/HIF1A/NFE2L2/DOCK5 6 GO:0150115 cell-substrate junction organization 4/380 101/18722 0.14970570768389 0.326909471248829 PTEN/IQGAP1/ACTN1/RAB8B 4 GO:0000724 double-strand break repair via homologous recombination 5/380 138/18722 0.149842911554639 0.326909471248829 SMCHD1/WAS/NABP1/ACTR2/NBN 5 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 3/380 66/18722 0.150208021490959 0.326909471248829 PTPRC/BCL6/NBN 3 GO:0016444 somatic cell DNA recombination 3/380 66/18722 0.150208021490959 0.326909471248829 PTPRC/BCL6/NBN 3 GO:0050918 positive chemotaxis 3/380 66/18722 0.150208021490959 0.326909471248829 CXCL8/FPR2/CORO1A 3 GO:0072678 T cell migration 3/380 66/18722 0.150208021490959 0.326909471248829 AIF1/MSN/PYCARD 3 GO:0000038 very long-chain fatty acid metabolic process 2/380 34/18722 0.151142560733225 0.326909471248829 ACSL1/ELOVL5 2 GO:0014072 response to isoquinoline alkaloid 2/380 34/18722 0.151142560733225 0.326909471248829 AIF1/CXCR4 2 GO:0019076 viral release from host cell 2/380 34/18722 0.151142560733225 0.326909471248829 VPS4B/RAB7A 2 GO:0032770 positive regulation of monooxygenase activity 2/380 34/18722 0.151142560733225 0.326909471248829 IL1B/HIF1A 2 GO:0035308 negative regulation of protein dephosphorylation 2/380 34/18722 0.151142560733225 0.326909471248829 BOD1L1/PPP1R15A 2 GO:0035890 exit from host 2/380 34/18722 0.151142560733225 0.326909471248829 VPS4B/RAB7A 2 GO:0035891 exit from host cell 2/380 34/18722 0.151142560733225 0.326909471248829 VPS4B/RAB7A 2 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 2/380 34/18722 0.151142560733225 0.326909471248829 SEC14L1/USP15 2 GO:0043278 response to morphine 2/380 34/18722 0.151142560733225 0.326909471248829 AIF1/CXCR4 2 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2/380 34/18722 0.151142560733225 0.326909471248829 CD44/DDX5 2 GO:0044319 wound healing, spreading of cells 2/380 34/18722 0.151142560733225 0.326909471248829 PTEN/CD44 2 GO:0048261 negative regulation of receptor-mediated endocytosis 2/380 34/18722 0.151142560733225 0.326909471248829 SDCBP/PICALM 2 GO:0055094 response to lipoprotein particle 2/380 34/18722 0.151142560733225 0.326909471248829 FCER1G/ITGB2 2 GO:0070232 regulation of T cell apoptotic process 2/380 34/18722 0.151142560733225 0.326909471248829 TSC22D3/HIF1A 2 GO:0090505 epiboly involved in wound healing 2/380 34/18722 0.151142560733225 0.326909471248829 PTEN/CD44 2 GO:0098751 bone cell development 2/380 34/18722 0.151142560733225 0.326909471248829 TYROBP/PTPN6 2 GO:0051648 vesicle localization 6/380 177/18722 0.151931831057212 0.328448853765847 LRRK2/MYO1F/PTEN/RAB27A/PICALM/CUL3 6 GO:0030216 keratinocyte differentiation 5/380 139/18722 0.153035391151192 0.330665755880254 ZFP36/TXNIP/STK4/ZFP36L1/FOSL2 5 GO:0010522 regulation of calcium ion transport into cytosol 4/380 102/18722 0.153497748571701 0.33115790382127 LYN/CORO1A/CYBA/PTPN6 4 GO:0014897 striated muscle hypertrophy 4/380 102/18722 0.153497748571701 0.33115790382127 RGS2/TNFRSF1B/PPP3CA/PAK1 4 GO:0045833 negative regulation of lipid metabolic process 4/380 102/18722 0.153497748571701 0.33115790382127 SORL1/HCAR2/IL1B/PPP2R5A 4 GO:0006513 protein monoubiquitination 3/380 67/18722 0.155037387030588 0.333629742924055 UBE2D3/UBE2B/CUL3 3 GO:0016445 somatic diversification of immunoglobulins 3/380 67/18722 0.155037387030588 0.333629742924055 PTPRC/BCL6/NBN 3 GO:0032890 regulation of organic acid transport 3/380 67/18722 0.155037387030588 0.333629742924055 RGS2/ACSL1/IL1B 3 GO:0061180 mammary gland epithelium development 3/380 67/18722 0.155037387030588 0.333629742924055 CEBPB/HIF1A/MAPK1 3 GO:1903317 regulation of protein maturation 3/380 67/18722 0.155037387030588 0.333629742924055 LRRK2/CARD16/MYH9 3 GO:0050803 regulation of synapse structure or activity 7/380 218/18722 0.156230906221751 0.335911021669442 SRGN/LRRK2/TUBA1A/LILRB2/PTEN/ACTR2/YWHAZ 7 GO:0000725 recombinational repair 5/380 140/18722 0.15625613050503 0.335911021669442 SMCHD1/WAS/NABP1/ACTR2/NBN 5 GO:0061564 axon development 13/380 467/18722 0.156888178812048 0.336134082222219 PLXNC1/RAC2/ACTB/S100A6/TSPO/PTEN/NUMB/VASP/PICALM/RHOG/NIN/PAK2/PAK1 13 GO:0030004 cellular monovalent inorganic cation homeostasis 4/380 103/18722 0.157325805393212 0.336134082222219 LRRK2/SLC11A1/MAPK1/RAB7A 4 GO:0050773 regulation of dendrite development 4/380 103/18722 0.157325805393212 0.336134082222219 PREX1/IQGAP1/ACTR2/PPP3CA 4 GO:0090277 positive regulation of peptide hormone secretion 4/380 103/18722 0.157325805393212 0.336134082222219 GLUL/NADK/HIF1A/RAB8B 4 GO:0001936 regulation of endothelial cell proliferation 6/380 179/18722 0.157576401307545 0.336134082222219 LRG1/ALOX5/CYBA/STAT3/RICTOR/HIF1A 6 GO:1901991 negative regulation of mitotic cell cycle phase transition 6/380 179/18722 0.157576401307545 0.336134082222219 DUSP1/NABP1/PTEN/ZFP36L1/ZFP36L2/NBN 6 GO:0000731 DNA synthesis involved in DNA repair 2/380 35/18722 0.158264783931784 0.336134082222219 CDKN2D/USP10 2 GO:0001569 branching involved in blood vessel morphogenesis 2/380 35/18722 0.158264783931784 0.336134082222219 STK4/TGFBR2 2 GO:0003298 physiological muscle hypertrophy 2/380 35/18722 0.158264783931784 0.336134082222219 RGS2/PAK1 2 GO:0003301 physiological cardiac muscle hypertrophy 2/380 35/18722 0.158264783931784 0.336134082222219 RGS2/PAK1 2 GO:0006739 NADP metabolic process 2/380 35/18722 0.158264783931784 0.336134082222219 NADK/TALDO1 2 GO:0009119 ribonucleoside metabolic process 2/380 35/18722 0.158264783931784 0.336134082222219 CDA/APOBEC3A 2 GO:0010664 negative regulation of striated muscle cell apoptotic process 2/380 35/18722 0.158264783931784 0.336134082222219 CFLAR/NFE2L2 2 GO:0010837 regulation of keratinocyte proliferation 2/380 35/18722 0.158264783931784 0.336134082222219 ZFP36/ZFP36L1 2 GO:0021955 central nervous system neuron axonogenesis 2/380 35/18722 0.158264783931784 0.336134082222219 PTEN/NIN 2 GO:0032232 negative regulation of actin filament bundle assembly 2/380 35/18722 0.158264783931784 0.336134082222219 WAS/PAK2 2 GO:0032350 regulation of hormone metabolic process 2/380 35/18722 0.158264783931784 0.336134082222219 EGR1/HIF1A 2 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 2/380 35/18722 0.158264783931784 0.336134082222219 SDCBP/N4BP1 2 GO:0045454 cell redox homeostasis 2/380 35/18722 0.158264783931784 0.336134082222219 SLC11A1/NFE2L2 2 GO:0060236 regulation of mitotic spindle organization 2/380 35/18722 0.158264783931784 0.336134082222219 HSPA1A/VPS4B 2 GO:0061049 cell growth involved in cardiac muscle cell development 2/380 35/18722 0.158264783931784 0.336134082222219 RGS2/PAK1 2 GO:0090504 epiboly 2/380 35/18722 0.158264783931784 0.336134082222219 PTEN/CD44 2 GO:1905508 protein localization to microtubule organizing center 2/380 35/18722 0.158264783931784 0.336134082222219 SNX10/CEP350 2 GO:2000403 positive regulation of lymphocyte migration 2/380 35/18722 0.158264783931784 0.336134082222219 AIF1/PYCARD 2 GO:0034764 positive regulation of transmembrane transport 7/380 219/18722 0.15878628699167 0.337072644315651 ACSL1/CTSS/TMSB4X/OSBPL8/VMP1/IFNGR2/NFE2L2 7 GO:0008584 male gonad development 5/380 141/18722 0.159504688644052 0.337920138272917 TNFSF10/NCOA1/KDM5A/SF1/NCOA4 5 GO:0016241 regulation of macroautophagy 5/380 141/18722 0.159504688644052 0.337920138272917 LRRK2/RALB/BNIP3L/HIF1A/SH3GLB1 5 GO:0035296 regulation of tube diameter 5/380 141/18722 0.159504688644052 0.337920138272917 SOD2/PTGS2/RGS2/KLF2/DOCK5 5 GO:0097746 blood vessel diameter maintenance 5/380 141/18722 0.159504688644052 0.337920138272917 SOD2/PTGS2/RGS2/KLF2/DOCK5 5 GO:0032922 circadian regulation of gene expression 3/380 68/18722 0.159914748516132 0.338281198784125 NAMPT/EGR1/KDM5A 3 GO:0042698 ovulation cycle 3/380 68/18722 0.159914748516132 0.338281198784125 ARRB2/EGR1/NCOA1 3 GO:0046637 regulation of alpha-beta T cell differentiation 3/380 68/18722 0.159914748516132 0.338281198784125 BCL6/NFKBIZ/TGFBR2 3 GO:0035150 regulation of tube size 5/380 142/18722 0.162780618878313 0.343486428824353 SOD2/PTGS2/RGS2/KLF2/DOCK5 5 GO:0046546 development of primary male sexual characteristics 5/380 142/18722 0.162780618878313 0.343486428824353 TNFSF10/NCOA1/KDM5A/SF1/NCOA4 5 GO:0097553 calcium ion transmembrane import into cytosol 5/380 142/18722 0.162780618878313 0.343486428824353 PTPRC/LYN/CORO1A/CYBA/PTPN6 5 GO:2000045 regulation of G1/S transition of mitotic cell cycle 5/380 142/18722 0.162780618878313 0.343486428824353 AIF1/PTEN/BID/DDX3X/PTPN6 5 GO:0051321 meiotic cell cycle 8/380 261/18722 0.162780935690786 0.343486428824353 DUSP1/ACTR2/PRKAR1A/ACTR3/UBE2B/STAG2/MYH9/NBN 8 GO:0099504 synaptic vesicle cycle 6/380 181/18722 0.163311496316229 0.344434356025513 LRRK2/ACTB/PRKCB/PTEN/STX3/PICALM 6 GO:0030336 negative regulation of cell migration 10/380 344/18722 0.163685706558013 0.345051750758182 IFITM1/AIF1/DUSP1/TRIB1/ARHGDIB/CNN2/PTEN/OSBPL8/STAT3/NFE2L2 10 GO:0034605 cellular response to heat 3/380 69/18722 0.164838349627963 0.345329244767519 PTGS2/LYN/HSPA1A 3 GO:0045669 positive regulation of osteoblast differentiation 3/380 69/18722 0.164838349627963 0.345329244767519 IFITM1/IL6R/CEBPB 3 GO:0050688 regulation of defense response to virus 3/380 69/18722 0.164838349627963 0.345329244767519 SEC14L1/FGL2/PYCARD 3 GO:0050810 regulation of steroid biosynthetic process 3/380 69/18722 0.164838349627963 0.345329244767519 TSPO/EGR1/SF1 3 GO:0051966 regulation of synaptic transmission, glutamatergic 3/380 69/18722 0.164838349627963 0.345329244767519 PTGS2/LRRK2/GLUL 3 GO:1901224 positive regulation of NIK/NF-kappaB signaling 3/380 69/18722 0.164838349627963 0.345329244767519 LAPTM5/IL1B/DDX3X 3 GO:0040029 regulation of gene expression, epigenetic 4/380 105/18722 0.165086765783724 0.345329244767519 SPI1/SMCHD1/KLF2/IFI16 4 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 4/380 105/18722 0.165086765783724 0.345329244767519 RAC2/ACTR2/CDC42EP3/ACTR3 4 GO:2001022 positive regulation of response to DNA damage stimulus 4/380 105/18722 0.165086765783724 0.345329244767519 SMCHD1/WAS/ACTR2/DDX5 4 GO:0008207 C21-steroid hormone metabolic process 2/380 36/18722 0.165448178898063 0.345329244767519 TSPO/EGR1 2 GO:0010923 negative regulation of phosphatase activity 2/380 36/18722 0.165448178898063 0.345329244767519 BOD1L1/PPP1R15A 2 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 2/380 36/18722 0.165448178898063 0.345329244767519 NADK/HIF1A 2 GO:0043949 regulation of cAMP-mediated signaling 2/380 36/18722 0.165448178898063 0.345329244767519 RGS2/UBE2B 2 GO:0045191 regulation of isotype switching 2/380 36/18722 0.165448178898063 0.345329244767519 PTPRC/BCL6 2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 2/380 36/18722 0.165448178898063 0.345329244767519 NCF1/PLAUR 2 GO:0051385 response to mineralocorticoid 2/380 36/18722 0.165448178898063 0.345329244767519 FOS/CYBA 2 GO:0060338 regulation of type I interferon-mediated signaling pathway 2/380 36/18722 0.165448178898063 0.345329244767519 PTPN6/ADAR 2 GO:0071402 cellular response to lipoprotein particle stimulus 2/380 36/18722 0.165448178898063 0.345329244767519 FCER1G/ITGB2 2 GO:0090313 regulation of protein targeting to membrane 2/380 36/18722 0.165448178898063 0.345329244767519 ITGB2/PAK1 2 GO:1901658 glycosyl compound catabolic process 2/380 36/18722 0.165448178898063 0.345329244767519 CDA/APOBEC3A 2 GO:0030010 establishment of cell polarity 5/380 143/18722 0.166083469070935 0.346484478579019 MSN/RICTOR/MYH9/PAK1/FLOT2 5 GO:0099565 chemical synaptic transmission, postsynaptic 4/380 106/18722 0.1690180547668 0.352259577725097 LRRK2/ARRB2/PTEN/PPP3CA 4 GO:1905477 positive regulation of protein localization to membrane 4/380 106/18722 0.1690180547668 0.352259577725097 ITGB2/STX3/RHOG/PAK1 4 GO:0007612 learning 5/380 144/18722 0.169412781906781 0.352735069506006 PTGS2/FOS/BTG2/ACTR2/HIF1A 5 GO:0010324 membrane invagination 5/380 144/18722 0.169412781906781 0.352735069506006 AIF1/RAC2/ITGB2/RHOG/MYH9 5 GO:0001990 regulation of systemic arterial blood pressure by hormone 2/380 37/18722 0.172687348668456 0.357961293051535 CYBA/MME 2 GO:0033363 secretory granule organization 2/380 37/18722 0.172687348668456 0.357961293051535 SRGN/LYST 2 GO:0034260 negative regulation of GTPase activity 2/380 37/18722 0.172687348668456 0.357961293051535 LRRK2/ARRB2 2 GO:0042401 cellular biogenic amine biosynthetic process 2/380 37/18722 0.172687348668456 0.357961293051535 SAT1/OAZ1 2 GO:0043029 T cell homeostasis 2/380 37/18722 0.172687348668456 0.357961293051535 CORO1A/TSC22D3 2 GO:0045616 regulation of keratinocyte differentiation 2/380 37/18722 0.172687348668456 0.357961293051535 ZFP36/ZFP36L1 2 GO:0048009 insulin-like growth factor receptor signaling pathway 2/380 37/18722 0.172687348668456 0.357961293051535 IGF2R/PHIP 2 GO:0060416 response to growth hormone 2/380 37/18722 0.172687348668456 0.357961293051535 LYN/STAT3 2 GO:0007269 neurotransmitter secretion 5/380 145/18722 0.172768095158757 0.357961293051535 LRRK2/PRKCB/STX3/MCTP2/STXBP3 5 GO:0099643 signal release from synapse 5/380 145/18722 0.172768095158757 0.357961293051535 LRRK2/PRKCB/STX3/MCTP2/STXBP3 5 GO:0010927 cellular component assembly involved in morphogenesis 4/380 107/18722 0.17298213169167 0.358054412372542 CFLAR/PRKAR1A/DICER1/TMOD3 4 GO:0051341 regulation of oxidoreductase activity 4/380 107/18722 0.17298213169167 0.358054412372542 LRRK2/CYBA/IL1B/HIF1A 4 GO:0040013 negative regulation of locomotion 11/380 391/18722 0.173585177163834 0.359127125202168 IFITM1/AIF1/DUSP1/TRIB1/WAS/ARHGDIB/CNN2/PTEN/OSBPL8/STAT3/NFE2L2 11 GO:0033555 multicellular organismal response to stress 3/380 71/18722 0.174817283447507 0.361323179795117 TSPO/PTEN/PPP3CA 3 GO:0071230 cellular response to amino acid stimulus 3/380 71/18722 0.174817283447507 0.361323179795117 CYBA/CEBPB/CPEB4 3 GO:0002040 sprouting angiogenesis 6/380 185/18722 0.175044104354058 0.361439191584318 PTGS2/KLF2/ALOX5/GLUL/JAK1/RNF213 6 GO:0051896 regulation of protein kinase B signaling 6/380 185/18722 0.175044104354058 0.361439191584318 OSM/ARRB2/PTEN/OSBPL8/HCLS1/RICTOR 6 GO:0046486 glycerolipid metabolic process 11/380 392/18722 0.175585716858131 0.362380853262274 SORL1/ACSL1/PLEK/MBOAT7/PTEN/LPGAT1/FAM126B/LPCAT2/OSBPL8/PLSCR1/CAT 11 GO:0048813 dendrite morphogenesis 5/380 146/18722 0.176148941951618 0.363366180791575 LRRK2/PTEN/ACTR2/PICALM/PPP3CA 5 GO:0022037 metencephalon development 4/380 108/18722 0.176978177837509 0.364721451650536 AIF1/AGTPBP1/NCOA1/PAK1 4 GO:0034446 substrate adhesion-dependent cell spreading 4/380 108/18722 0.176978177837509 0.364721451650536 MEGF9/PREX1/MYADM/DOCK5 4 GO:0008217 regulation of blood pressure 6/380 186/18722 0.178030205015288 0.366532775031475 NAMPT/SOD2/PTGS2/CYBA/HBB/MME 6 GO:0120032 regulation of plasma membrane bounded cell projection assembly 6/380 186/18722 0.178030205015288 0.366532775031475 RAC2/WAS/ACTR2/CDC42EP3/RHOG/ACTR3 6 GO:0033627 cell adhesion mediated by integrin 3/380 72/18722 0.179869145358308 0.368036201025968 LYN/ITGB2/PTPN6 3 GO:0042246 tissue regeneration 3/380 72/18722 0.179869145358308 0.368036201025968 CFLAR/TGFBR2/PPP3CA 3 GO:1903036 positive regulation of response to wounding 3/380 72/18722 0.179869145358308 0.368036201025968 CXCR4/CLEC7A/NFE2L2 3 GO:1905818 regulation of chromosome separation 3/380 72/18722 0.179869145358308 0.368036201025968 DUSP1/PLSCR1/CUL3 3 GO:0001825 blastocyst formation 2/380 38/18722 0.17997708909676 0.368036201025968 JUNB/CUL3 2 GO:0006882 cellular zinc ion homeostasis 2/380 38/18722 0.17997708909676 0.368036201025968 S100A8/S100A9 2 GO:0009309 amine biosynthetic process 2/380 38/18722 0.17997708909676 0.368036201025968 SAT1/OAZ1 2 GO:0030279 negative regulation of ossification 2/380 38/18722 0.17997708909676 0.368036201025968 SRGN/HIF1A 2 GO:0035337 fatty-acyl-CoA metabolic process 2/380 38/18722 0.17997708909676 0.368036201025968 ACSL1/ELOVL5 2 GO:0046676 negative regulation of insulin secretion 2/380 38/18722 0.17997708909676 0.368036201025968 MIDN/PPP3CA 2 GO:0048713 regulation of oligodendrocyte differentiation 2/380 38/18722 0.17997708909676 0.368036201025968 CXCR4/TNFRSF1B 2 GO:0072524 pyridine-containing compound metabolic process 2/380 38/18722 0.17997708909676 0.368036201025968 NAMPT/NADK 2 GO:1901031 regulation of response to reactive oxygen species 2/380 38/18722 0.17997708909676 0.368036201025968 LRRK2/NFE2L2 2 GO:1901186 positive regulation of ERBB signaling pathway 2/380 38/18722 0.17997708909676 0.368036201025968 NCF1/PLAUR 2 GO:0032414 positive regulation of ion transmembrane transporter activity 4/380 109/18722 0.181005370927014 0.368358460328951 CTSS/TMSB4X/VMP1/IFNGR2 4 GO:0061136 regulation of proteasomal protein catabolic process 6/380 187/18722 0.181036879856457 0.368358460328951 LRRK2/TRIB1/SDCBP/HSPA1A/NFE2L2/N4BP1 6 GO:0043484 regulation of RNA splicing 5/380 148/18722 0.182985346982639 0.368358460328951 CELF2/PTBP3/DDX5/HSPA1A/SF1 5 GO:0060491 regulation of cell projection assembly 6/380 188/18722 0.184063820119405 0.368358460328951 RAC2/WAS/ACTR2/CDC42EP3/RHOG/ACTR3 6 GO:0002637 regulation of immunoglobulin production 3/380 73/18722 0.18496030769773 0.368358460328951 PTPRC/BCL6/HLA-E 3 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 3/380 73/18722 0.18496030769773 0.368358460328951 NCF1/PLAUR/RAB7A 3 GO:0045739 positive regulation of DNA repair 3/380 73/18722 0.18496030769773 0.368358460328951 SMCHD1/WAS/ACTR2 3 GO:0006939 smooth muscle contraction 4/380 110/18722 0.185062885669038 0.368358460328951 PTGS2/RGS2/PROK2/DOCK5 4 GO:0007088 regulation of mitotic nuclear division 4/380 110/18722 0.185062885669038 0.368358460328951 DUSP1/IL1B/CUL3/PHIP 4 GO:0001865 NK T cell differentiation 1/380 10/18722 0.18544043386572 0.368358460328951 TGFBR2 1 GO:0001915 negative regulation of T cell mediated cytotoxicity 1/380 10/18722 0.18544043386572 0.368358460328951 PTPRC 1 GO:0002002 regulation of angiotensin levels in blood 1/380 10/18722 0.18544043386572 0.368358460328951 MME 1 GO:0002003 angiotensin maturation 1/380 10/18722 0.18544043386572 0.368358460328951 MME 1 GO:0002524 hypersensitivity 1/380 10/18722 0.18544043386572 0.368358460328951 HLA-E 1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity 1/380 10/18722 0.18544043386572 0.368358460328951 SPI1 1 GO:0003056 regulation of vascular associated smooth muscle contraction 1/380 10/18722 0.18544043386572 0.368358460328951 DOCK5 1 GO:0003330 regulation of extracellular matrix constituent secretion 1/380 10/18722 0.18544043386572 0.368358460328951 TNFRSF1B 1 GO:0005984 disaccharide metabolic process 1/380 10/18722 0.18544043386572 0.368358460328951 MGAM 1 GO:0009750 response to fructose 1/380 10/18722 0.18544043386572 0.368358460328951 PTGS2 1 GO:0014041 regulation of neuron maturation 1/380 10/18722 0.18544043386572 0.368358460328951 LRRK2 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/380 10/18722 0.18544043386572 0.368358460328951 ACSL1 1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1/380 10/18722 0.18544043386572 0.368358460328951 EGLN1 1 GO:0030214 hyaluronan catabolic process 1/380 10/18722 0.18544043386572 0.368358460328951 CD44 1 GO:0031642 negative regulation of myelination 1/380 10/18722 0.18544043386572 0.368358460328951 PTEN 1 GO:0031915 positive regulation of synaptic plasticity 1/380 10/18722 0.18544043386572 0.368358460328951 PTGS2 1 GO:0033080 immature T cell proliferation in thymus 1/380 10/18722 0.18544043386572 0.368358460328951 IL1B 1 GO:0033131 regulation of glucokinase activity 1/380 10/18722 0.18544043386572 0.368358460328951 MIDN 1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway 1/380 10/18722 0.18544043386572 0.368358460328951 NAMPT 1 GO:0034756 regulation of iron ion transport 1/380 10/18722 0.18544043386572 0.368358460328951 B2M 1 GO:0035520 monoubiquitinated protein deubiquitination 1/380 10/18722 0.18544043386572 0.368358460328951 USP15 1 GO:0036109 alpha-linolenic acid metabolic process 1/380 10/18722 0.18544043386572 0.368358460328951 ELOVL5 1 GO:0042711 maternal behavior 1/380 10/18722 0.18544043386572 0.368358460328951 PTEN 1 GO:0042989 sequestering of actin monomers 1/380 10/18722 0.18544043386572 0.368358460328951 TMSB4X 1 GO:0044351 macropinocytosis 1/380 10/18722 0.18544043386572 0.368358460328951 PYCARD 1 GO:0044557 relaxation of smooth muscle 1/380 10/18722 0.18544043386572 0.368358460328951 RGS2 1 GO:0045792 negative regulation of cell size 1/380 10/18722 0.18544043386572 0.368358460328951 PTEN 1 GO:0045835 negative regulation of meiotic nuclear division 1/380 10/18722 0.18544043386572 0.368358460328951 PRKAR1A 1 GO:0048755 branching morphogenesis of a nerve 1/380 10/18722 0.18544043386572 0.368358460328951 LRRK2 1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1/380 10/18722 0.18544043386572 0.368358460328951 EGLN1 1 GO:0051351 positive regulation of ligase activity 1/380 10/18722 0.18544043386572 0.368358460328951 TMSB4X 1 GO:0060736 prostate gland growth 1/380 10/18722 0.18544043386572 0.368358460328951 PTEN 1 GO:0070099 regulation of chemokine-mediated signaling pathway 1/380 10/18722 0.18544043386572 0.368358460328951 HIF1A 1 GO:0070383 DNA cytosine deamination 1/380 10/18722 0.18544043386572 0.368358460328951 APOBEC3A 1 GO:0071421 manganese ion transmembrane transport 1/380 10/18722 0.18544043386572 0.368358460328951 SLC11A1 1 GO:0072203 cell proliferation involved in metanephros development 1/380 10/18722 0.18544043386572 0.368358460328951 EGR1 1 GO:0090209 negative regulation of triglyceride metabolic process 1/380 10/18722 0.18544043386572 0.368358460328951 SORL1 1 GO:0097105 presynaptic membrane assembly 1/380 10/18722 0.18544043386572 0.368358460328951 PTEN 1 GO:0099171 presynaptic modulation of chemical synaptic transmission 1/380 10/18722 0.18544043386572 0.368358460328951 PRKCB 1 GO:1900246 positive regulation of RIG-I signaling pathway 1/380 10/18722 0.18544043386572 0.368358460328951 USP15 1 GO:1902023 L-arginine transport 1/380 10/18722 0.18544043386572 0.368358460328951 SLC11A1 1 GO:1903980 positive regulation of microglial cell activation 1/380 10/18722 0.18544043386572 0.368358460328951 LRRK2 1 GO:1904668 positive regulation of ubiquitin protein ligase activity 1/380 10/18722 0.18544043386572 0.368358460328951 PTEN 1 GO:1904896 ESCRT complex disassembly 1/380 10/18722 0.18544043386572 0.368358460328951 VPS4B 1 GO:1904903 ESCRT III complex disassembly 1/380 10/18722 0.18544043386572 0.368358460328951 VPS4B 1 GO:1905456 regulation of lymphoid progenitor cell differentiation 1/380 10/18722 0.18544043386572 0.368358460328951 SOS2 1 GO:2000121 regulation of removal of superoxide radicals 1/380 10/18722 0.18544043386572 0.368358460328951 NFE2L2 1 GO:2000288 positive regulation of myoblast proliferation 1/380 10/18722 0.18544043386572 0.368358460328951 MALAT1 1 GO:2000434 regulation of protein neddylation 1/380 10/18722 0.18544043386572 0.368358460328951 HIF1A 1 GO:2000510 positive regulation of dendritic cell chemotaxis 1/380 10/18722 0.18544043386572 0.368358460328951 SPI1 1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation 1/380 10/18722 0.18544043386572 0.368358460328951 WAS 1 GO:2001223 negative regulation of neuron migration 1/380 10/18722 0.18544043386572 0.368358460328951 STAT3 1 GO:0002701 negative regulation of production of molecular mediator of immune response 2/380 39/18722 0.187312383284967 0.370167029030254 BCL6/IRAK3 2 GO:0007618 mating 2/380 39/18722 0.187312383284967 0.370167029030254 PTEN/NCOA1 2 GO:0016233 telomere capping 2/380 39/18722 0.187312383284967 0.370167029030254 MAPK1/NBN 2 GO:0032506 cytokinetic process 2/380 39/18722 0.187312383284967 0.370167029030254 MYH9/VPS4B 2 GO:0032728 positive regulation of interferon-beta production 2/380 39/18722 0.187312383284967 0.370167029030254 IRF1/DDX3X 2 GO:0045622 regulation of T-helper cell differentiation 2/380 39/18722 0.187312383284967 0.370167029030254 BCL6/NFKBIZ 2 GO:0046326 positive regulation of glucose import 2/380 39/18722 0.187312383284967 0.370167029030254 OSBPL8/NFE2L2 2 GO:0051154 negative regulation of striated muscle cell differentiation 2/380 39/18722 0.187312383284967 0.370167029030254 RGS2/PAK1 2 GO:0090207 regulation of triglyceride metabolic process 2/380 39/18722 0.187312383284967 0.370167029030254 SORL1/MBOAT7 2 GO:0090224 regulation of spindle organization 2/380 39/18722 0.187312383284967 0.370167029030254 HSPA1A/VPS4B 2 GO:1902742 apoptotic process involved in development 2/380 39/18722 0.187312383284967 0.370167029030254 SPI1/TNFRSF1B 2 GO:0090288 negative regulation of cellular response to growth factor stimulus 4/380 111/18722 0.189149894287692 0.373623974957265 SORL1/CFLAR/UBE2D1/UBE2D3 4 GO:0009755 hormone-mediated signaling pathway 6/380 190/18722 0.190177245612514 0.375478151593937 ACSL1/NCOA1/TAF7/DDX5/PAK1/NCOA4 6 GO:1904062 regulation of cation transmembrane transport 10/380 357/18722 0.191480780724153 0.377875632044169 RGS2/LYN/CTSS/TMSB4X/CORO1A/CYBA/PTEN/VMP1/IFNGR2/PTPN6 10 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 8/380 273/18722 0.192367330423958 0.379448367184658 SELL/JAML/CD177/MBP/ITGB2/PECAM1/MYADM/TGFBR2 8 GO:0030902 hindbrain development 5/380 151/18722 0.193419545701053 0.380060162976729 C5AR1/AIF1/AGTPBP1/NCOA1/PAK1 5 GO:0002714 positive regulation of B cell mediated immunity 2/380 40/18722 0.194688396159731 0.380060162976729 PTPRC/HLA-E 2 GO:0002891 positive regulation of immunoglobulin mediated immune response 2/380 40/18722 0.194688396159731 0.380060162976729 PTPRC/HLA-E 2 GO:0032892 positive regulation of organic acid transport 2/380 40/18722 0.194688396159731 0.380060162976729 ACSL1/IL1B 2 GO:0035329 hippo signaling 2/380 40/18722 0.194688396159731 0.380060162976729 STK4/PJA2 2 GO:0044275 cellular carbohydrate catabolic process 2/380 40/18722 0.194688396159731 0.380060162976729 MGAM/PYGL 2 GO:0055069 zinc ion homeostasis 2/380 40/18722 0.194688396159731 0.380060162976729 S100A8/S100A9 2 GO:1901661 quinone metabolic process 2/380 40/18722 0.194688396159731 0.380060162976729 CYP4F3/NQO2 2 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 2/380 40/18722 0.194688396159731 0.380060162976729 ALOX5/ITGB2 2 GO:0008088 axo-dendritic transport 3/380 75/18722 0.195253717694147 0.380060162976729 AGTPBP1/HIF1A/FLOT2 3 GO:0036465 synaptic vesicle recycling 3/380 75/18722 0.195253717694147 0.380060162976729 LRRK2/ACTB/PICALM 3 GO:0043627 response to estrogen 3/380 75/18722 0.195253717694147 0.380060162976729 TGFBR2/MAPK1/NCOA4 3 GO:0051453 regulation of intracellular pH 3/380 75/18722 0.195253717694147 0.380060162976729 LRRK2/SLC11A1/RAB7A 3 GO:2001259 positive regulation of cation channel activity 3/380 75/18722 0.195253717694147 0.380060162976729 CTSS/TMSB4X/IFNGR2 3 GO:0007160 cell-matrix adhesion 7/380 233/18722 0.196466325420662 0.380060162976729 BCL6/ITGB2/PTEN/IQGAP1/ZYX/CD44/ACTN1 7 GO:0043270 positive regulation of ion transport 8/380 275/18722 0.197506530631664 0.380060162976729 CTSS/TMSB4X/CEBPB/IL1B/ARRB2/TSPO/VMP1/IFNGR2 8 GO:0010498 proteasomal protein catabolic process 13/380 490/18722 0.198717600861607 0.380060162976729 LRRK2/PELI1/TRIB1/ARRB2/SDCBP/FBXL5/UBE2D3/UBE2B/HSPA1A/CUL3/PSMB9/NFE2L2/N4BP1 13 GO:0007548 sex differentiation 8/380 276/18722 0.200097191253947 0.380060162976729 BASP1/CEBPB/ARRB2/TNFSF10/NCOA1/KDM5A/SF1/NCOA4 8 GO:0045685 regulation of glial cell differentiation 3/380 76/18722 0.200452591246611 0.380060162976729 CXCR4/TNFRSF1B/DICER1 3 GO:0120254 olefinic compound metabolic process 5/380 153/18722 0.200489734384726 0.380060162976729 PTGS2/CYP4F3/ELOVL5/ALOX5/EGR1 5 GO:0021987 cerebral cortex development 4/380 114/18722 0.20157957910623 0.380060162976729 BCL2A1/MBOAT7/NCOA1/HIF1A 4 GO:0051261 protein depolymerization 4/380 114/18722 0.20157957910623 0.380060162976729 PLEK/CAPZA1/VPS4B/TMOD3 4 GO:1901800 positive regulation of proteasomal protein catabolic process 4/380 114/18722 0.20157957910623 0.380060162976729 LRRK2/TRIB1/HSPA1A/NFE2L2 4 GO:0001765 membrane raft assembly 1/380 11/18722 0.201982366055279 0.380060162976729 FLOT2 1 GO:0001787 natural killer cell proliferation 1/380 11/18722 0.201982366055279 0.380060162976729 HLA-E 1 GO:0001867 complement activation, lectin pathway 1/380 11/18722 0.201982366055279 0.380060162976729 FCN1 1 GO:0002327 immature B cell differentiation 1/380 11/18722 0.201982366055279 0.380060162976729 SPI1 1 GO:0002732 positive regulation of dendritic cell cytokine production 1/380 11/18722 0.201982366055279 0.380060162976729 CLEC7A 1 GO:0003093 regulation of glomerular filtration 1/380 11/18722 0.201982366055279 0.380060162976729 CYBA 1 GO:0003157 endocardium development 1/380 11/18722 0.201982366055279 0.380060162976729 STK4 1 GO:0006002 fructose 6-phosphate metabolic process 1/380 11/18722 0.201982366055279 0.380060162976729 TALDO1 1 GO:0006971 hypotonic response 1/380 11/18722 0.201982366055279 0.380060162976729 TSPO 1 GO:0008611 ether lipid biosynthetic process 1/380 11/18722 0.201982366055279 0.380060162976729 LPCAT2 1 GO:0009313 oligosaccharide catabolic process 1/380 11/18722 0.201982366055279 0.380060162976729 CTBS 1 GO:0010269 response to selenium ion 1/380 11/18722 0.201982366055279 0.380060162976729 SOD2 1 GO:0010918 positive regulation of mitochondrial membrane potential 1/380 11/18722 0.201982366055279 0.380060162976729 BID 1 GO:0014010 Schwann cell proliferation 1/380 11/18722 0.201982366055279 0.380060162976729 DICER1 1 GO:0014854 response to inactivity 1/380 11/18722 0.201982366055279 0.380060162976729 CAT 1 GO:0021702 cerebellar Purkinje cell differentiation 1/380 11/18722 0.201982366055279 0.380060162976729 AGTPBP1 1 GO:0032308 positive regulation of prostaglandin secretion 1/380 11/18722 0.201982366055279 0.380060162976729 IL1B 1 GO:0032493 response to bacterial lipoprotein 1/380 11/18722 0.201982366055279 0.380060162976729 TLR1 1 GO:0033033 negative regulation of myeloid cell apoptotic process 1/380 11/18722 0.201982366055279 0.380060162976729 CXCR2 1 GO:0033083 regulation of immature T cell proliferation 1/380 11/18722 0.201982366055279 0.380060162976729 IL1B 1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway 1/380 11/18722 0.201982366055279 0.380060162976729 PAK1 1 GO:0033197 response to vitamin E 1/380 11/18722 0.201982366055279 0.380060162976729 CAT 1 GO:0033210 leptin-mediated signaling pathway 1/380 11/18722 0.201982366055279 0.380060162976729 STAT3 1 GO:0033327 Leydig cell differentiation 1/380 11/18722 0.201982366055279 0.380060162976729 SF1 1 GO:0033625 positive regulation of integrin activation 1/380 11/18722 0.201982366055279 0.380060162976729 PLEK 1 GO:0033860 regulation of NAD(P)H oxidase activity 1/380 11/18722 0.201982366055279 0.380060162976729 CYBA 1 GO:0034454 microtubule anchoring at centrosome 1/380 11/18722 0.201982366055279 0.380060162976729 NIN 1 GO:0035457 cellular response to interferon-alpha 1/380 11/18722 0.201982366055279 0.380060162976729 IFNAR1 1 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/380 11/18722 0.201982366055279 0.380060162976729 SEC14L1 1 GO:0042447 hormone catabolic process 1/380 11/18722 0.201982366055279 0.380060162976729 HSD17B11 1 GO:0045060 negative thymic T cell selection 1/380 11/18722 0.201982366055279 0.380060162976729 PTPRC 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/380 11/18722 0.201982366055279 0.380060162976729 BCL6 1 GO:0045657 positive regulation of monocyte differentiation 1/380 11/18722 0.201982366055279 0.380060162976729 ZFP36L1 1 GO:0046504 glycerol ether biosynthetic process 1/380 11/18722 0.201982366055279 0.380060162976729 LPCAT2 1 GO:0046643 regulation of gamma-delta T cell activation 1/380 11/18722 0.201982366055279 0.380060162976729 PTPRC 1 GO:0048103 somatic stem cell division 1/380 11/18722 0.201982366055279 0.380060162976729 ZFP36L2 1 GO:0048853 forebrain morphogenesis 1/380 11/18722 0.201982366055279 0.380060162976729 PTEN 1 GO:0051081 nuclear membrane disassembly 1/380 11/18722 0.201982366055279 0.380060162976729 PRKCB 1 GO:0060159 regulation of dopamine receptor signaling pathway 1/380 11/18722 0.201982366055279 0.380060162976729 LRRK2 1 GO:0060433 bronchus development 1/380 11/18722 0.201982366055279 0.380060162976729 TGFBR2 1 GO:0060746 parental behavior 1/380 11/18722 0.201982366055279 0.380060162976729 PTEN 1 GO:0070243 regulation of thymocyte apoptotic process 1/380 11/18722 0.201982366055279 0.380060162976729 HIF1A 1 GO:0070944 neutrophil-mediated killing of bacterium 1/380 11/18722 0.201982366055279 0.380060162976729 TREM1 1 GO:0071492 cellular response to UV-A 1/380 11/18722 0.201982366055279 0.380060162976729 MME 1 GO:0071609 chemokine (C-C motif) ligand 5 production 1/380 11/18722 0.201982366055279 0.380060162976729 DDX3X 1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production 1/380 11/18722 0.201982366055279 0.380060162976729 DDX3X 1 GO:0072173 metanephric tubule morphogenesis 1/380 11/18722 0.201982366055279 0.380060162976729 CXCR2 1 GO:0090160 Golgi to lysosome transport 1/380 11/18722 0.201982366055279 0.380060162976729 LAPTM5 1 GO:0090219 negative regulation of lipid kinase activity 1/380 11/18722 0.201982366055279 0.380060162976729 PPP2R5A 1 GO:0090649 response to oxygen-glucose deprivation 1/380 11/18722 0.201982366055279 0.380060162976729 NAMPT 1 GO:0097048 dendritic cell apoptotic process 1/380 11/18722 0.201982366055279 0.380060162976729 LYN 1 GO:0097090 presynaptic membrane organization 1/380 11/18722 0.201982366055279 0.380060162976729 PTEN 1 GO:0097384 cellular lipid biosynthetic process 1/380 11/18722 0.201982366055279 0.380060162976729 LPCAT2 1 GO:0097396 response to interleukin-17 1/380 11/18722 0.201982366055279 0.380060162976729 IL17RA 1 GO:0097398 cellular response to interleukin-17 1/380 11/18722 0.201982366055279 0.380060162976729 IL17RA 1 GO:0097400 interleukin-17-mediated signaling pathway 1/380 11/18722 0.201982366055279 0.380060162976729 IL17RA 1 GO:0097494 regulation of vesicle size 1/380 11/18722 0.201982366055279 0.380060162976729 PICALM 1 GO:0098935 dendritic transport 1/380 11/18722 0.201982366055279 0.380060162976729 FLOT2 1 GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization 1/380 11/18722 0.201982366055279 0.380060162976729 NUMB 1 GO:0106049 regulation of cellular response to osmotic stress 1/380 11/18722 0.201982366055279 0.380060162976729 PTGS2 1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly 1/380 11/18722 0.201982366055279 0.380060162976729 DDX3X 1 GO:1900426 positive regulation of defense response to bacterium 1/380 11/18722 0.201982366055279 0.380060162976729 CYBA 1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation 1/380 11/18722 0.201982366055279 0.380060162976729 NFE2L2 1 GO:1902337 regulation of apoptotic process involved in morphogenesis 1/380 11/18722 0.201982366055279 0.380060162976729 TNFRSF1B 1 GO:1903299 regulation of hexokinase activity 1/380 11/18722 0.201982366055279 0.380060162976729 MIDN 1 GO:1903423 positive regulation of synaptic vesicle recycling 1/380 11/18722 0.201982366055279 0.380060162976729 LRRK2 1 GO:1903897 regulation of PERK-mediated unfolded protein response 1/380 11/18722 0.201982366055279 0.380060162976729 PPP1R15A 1 GO:1904181 positive regulation of membrane depolarization 1/380 11/18722 0.201982366055279 0.380060162976729 TSPO 1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 1/380 11/18722 0.201982366055279 0.380060162976729 CEBPB 1 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1/380 11/18722 0.201982366055279 0.380060162976729 MBP 1 GO:2000392 regulation of lamellipodium morphogenesis 1/380 11/18722 0.201982366055279 0.380060162976729 CD44 1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity 1/380 11/18722 0.201982366055279 0.380060162976729 PRKAR1A 1 GO:2000644 regulation of receptor catabolic process 1/380 11/18722 0.201982366055279 0.380060162976729 LAPTM5 1 GO:2000668 regulation of dendritic cell apoptotic process 1/380 11/18722 0.201982366055279 0.380060162976729 LYN 1 GO:2001053 regulation of mesenchymal cell apoptotic process 1/380 11/18722 0.201982366055279 0.380060162976729 HIF1A 1 GO:0001953 negative regulation of cell-matrix adhesion 2/380 41/18722 0.202100469190931 0.380060162976729 BCL6/PTEN 2 GO:0002251 organ or tissue specific immune response 2/380 41/18722 0.202100469190931 0.380060162976729 FFAR2/IL6R 2 GO:0050856 regulation of T cell receptor signaling pathway 2/380 41/18722 0.202100469190931 0.380060162976729 LAPTM5/PTPN6 2 GO:0051693 actin filament capping 2/380 41/18722 0.202100469190931 0.380060162976729 CAPZA1/TMOD3 2 GO:0060612 adipose tissue development 2/380 41/18722 0.202100469190931 0.380060162976729 SORL1/SPI1 2 GO:1900371 regulation of purine nucleotide biosynthetic process 2/380 41/18722 0.202100469190931 0.380060162976729 TMSB4X/STAT3 2 GO:1905521 regulation of macrophage migration 2/380 41/18722 0.202100469190931 0.380060162976729 C5AR1/MAPK1 2 GO:0016052 carbohydrate catabolic process 5/380 154/18722 0.204057569098531 0.383230068794801 MGAM/PYGL/STAT3/CTBS/HIF1A 5 GO:0030856 regulation of epithelial cell differentiation 5/380 154/18722 0.204057569098531 0.383230068794801 ZFP36/CEBPB/IL1B/ZFP36L1/BTG1 5 GO:0050770 regulation of axonogenesis 5/380 154/18722 0.204057569098531 0.383230068794801 PLXNC1/PTEN/NIN/PAK2/PAK1 5 GO:0000209 protein polyubiquitination 7/380 236/18722 0.20497047117286 0.384773911975647 PELI1/UBE2D1/UBE2D3/UBE2B/DDX3X/NPEPPS/CUL3 7 GO:0007492 endoderm development 3/380 77/18722 0.205684018891897 0.385942321669111 DUSP1/ITGB2/ZFP36L1 3 GO:0030278 regulation of ossification 4/380 115/18722 0.205776253540168 0.385944390497171 SRGN/ALOX5/HIF1A/MAPK1 4 GO:0007212 dopamine receptor signaling pathway 2/380 42/18722 0.209544115248815 0.391091752404711 LRRK2/ARRB2 2 GO:0014003 oligodendrocyte development 2/380 42/18722 0.209544115248815 0.391091752404711 LYN/PTEN 2 GO:0019432 triglyceride biosynthetic process 2/380 42/18722 0.209544115248815 0.391091752404711 ACSL1/LPGAT1 2 GO:0030574 collagen catabolic process 2/380 42/18722 0.209544115248815 0.391091752404711 MMP25/CTSS 2 GO:0030808 regulation of nucleotide biosynthetic process 2/380 42/18722 0.209544115248815 0.391091752404711 TMSB4X/STAT3 2 GO:0032689 negative regulation of interferon-gamma production 2/380 42/18722 0.209544115248815 0.391091752404711 PGLYRP1/LAPTM5 2 GO:0032691 negative regulation of interleukin-1 beta production 2/380 42/18722 0.209544115248815 0.391091752404711 ARRB2/CARD16 2 GO:0032965 regulation of collagen biosynthetic process 2/380 42/18722 0.209544115248815 0.391091752404711 VIM/ARRB2 2 GO:0035019 somatic stem cell population maintenance 2/380 42/18722 0.209544115248815 0.391091752404711 SPI1/ZFP36L2 2 GO:0051452 intracellular pH reduction 2/380 42/18722 0.209544115248815 0.391091752404711 SLC11A1/RAB7A 2 GO:2000404 regulation of T cell migration 2/380 42/18722 0.209544115248815 0.391091752404711 AIF1/PYCARD 2 GO:0007006 mitochondrial membrane organization 4/380 116/18722 0.20999826327469 0.391091752404711 BNIP3L/STAT3/BID/HSPA1A 4 GO:0018107 peptidyl-threonine phosphorylation 4/380 116/18722 0.20999826327469 0.391091752404711 LRRK2/PRKCB/TGFBR2/MAPK1 4 GO:0030518 intracellular steroid hormone receptor signaling pathway 4/380 116/18722 0.20999826327469 0.391091752404711 TAF7/DDX5/PAK1/NCOA4 4 GO:0035967 cellular response to topologically incorrect protein 4/380 116/18722 0.20999826327469 0.391091752404711 HSPA1A/CUL3/PPP1R15A/NFE2L2 4 GO:0043200 response to amino acid 4/380 116/18722 0.20999826327469 0.391091752404711 LYN/CYBA/CEBPB/CPEB4 4 GO:0030500 regulation of bone mineralization 3/380 78/18722 0.210946351568936 0.392203482516861 SRGN/ALOX5/HIF1A 3 GO:0032024 positive regulation of insulin secretion 3/380 78/18722 0.210946351568936 0.392203482516861 GLUL/NADK/HIF1A 3 GO:0035051 cardiocyte differentiation 5/380 156/18722 0.211256232981299 0.392203482516861 RGS2/KDM6B/ARRB2/PAK1/MAPK1 5 GO:0140694 non-membrane-bounded organelle assembly 10/380 367/18722 0.214191629238187 0.392203482516861 LCP1/HCK/CFLAR/MSN/PRKAR1A/STAG2/DDX3X/HSPA1A/VPS4B/TMOD3 10 GO:0014902 myotube differentiation 4/380 117/18722 0.214244775982742 0.392203482516861 CFLAR/CD53/MYH9/PPP3CA 4 GO:0072676 lymphocyte migration 4/380 117/18722 0.214244775982742 0.392203482516861 AIF1/MSN/PYCARD/CKLF 4 GO:0001895 retina homeostasis 3/380 79/18722 0.216237956896243 0.392203482516861 B2M/ACTB/LYZ 3 GO:0006446 regulation of translational initiation 3/380 79/18722 0.216237956896243 0.392203482516861 EIF1/DDX3X/PPP1R15A 3 GO:0050772 positive regulation of axonogenesis 3/380 79/18722 0.216237956896243 0.392203482516861 PLXNC1/NIN/PAK1 3 GO:1901184 regulation of ERBB signaling pathway 3/380 79/18722 0.216237956896243 0.392203482516861 NCF1/PLAUR/RAB7A 3 GO:0001709 cell fate determination 2/380 43/18722 0.217015013596282 0.392203482516861 MCL1/IFRD1 2 GO:0009268 response to pH 2/380 43/18722 0.217015013596282 0.392203482516861 CTSS/GPR65 2 GO:0014014 negative regulation of gliogenesis 2/380 43/18722 0.217015013596282 0.392203482516861 TSPO/DICER1 2 GO:0033173 calcineurin-NFAT signaling cascade 2/380 43/18722 0.217015013596282 0.392203482516861 CLEC7A/PPP3CA 2 GO:0042088 T-helper 1 type immune response 2/380 43/18722 0.217015013596282 0.392203482516861 SLC11A1/IL1B 2 GO:0090278 negative regulation of peptide hormone secretion 2/380 43/18722 0.217015013596282 0.392203482516861 MIDN/PPP3CA 2 GO:0098815 modulation of excitatory postsynaptic potential 2/380 43/18722 0.217015013596282 0.392203482516861 LRRK2/PTEN 2 GO:1903793 positive regulation of anion transport 2/380 43/18722 0.217015013596282 0.392203482516861 CEBPB/IL1B 2 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 2/380 43/18722 0.217015013596282 0.392203482516861 SOD2/PTEN 2 GO:0001821 histamine secretion 1/380 12/18722 0.218189233721304 0.392203482516861 LYN 1 GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure 1/380 12/18722 0.218189233721304 0.392203482516861 SOD2 1 GO:0002024 diet induced thermogenesis 1/380 12/18722 0.218189233721304 0.392203482516861 SORL1 1 GO:0002328 pro-B cell differentiation 1/380 12/18722 0.218189233721304 0.392203482516861 SOS2 1 GO:0002424 T cell mediated immune response to tumor cell 1/380 12/18722 0.218189233721304 0.392203482516861 HLA-A 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/380 12/18722 0.218189233721304 0.392203482516861 HLA-E 1 GO:0002903 negative regulation of B cell apoptotic process 1/380 12/18722 0.218189233721304 0.392203482516861 BCL6 1 GO:0006703 estrogen biosynthetic process 1/380 12/18722 0.218189233721304 0.392203482516861 HSD17B11 1 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process 1/380 12/18722 0.218189233721304 0.392203482516861 TYMP 1 GO:0014889 muscle atrophy 1/380 12/18722 0.218189233721304 0.392203482516861 CFLAR 1 GO:0016188 synaptic vesicle maturation 1/380 12/18722 0.218189233721304 0.392203482516861 PICALM 1 GO:0016554 cytidine to uridine editing 1/380 12/18722 0.218189233721304 0.392203482516861 APOBEC3A 1 GO:0021670 lateral ventricle development 1/380 12/18722 0.218189233721304 0.392203482516861 NUMB 1 GO:0030238 male sex determination 1/380 12/18722 0.218189233721304 0.392203482516861 SF1 1 GO:0030397 membrane disassembly 1/380 12/18722 0.218189233721304 0.392203482516861 PRKCB 1 GO:0031953 negative regulation of protein autophosphorylation 1/380 12/18722 0.218189233721304 0.392203482516861 PTPRC 1 GO:0032306 regulation of prostaglandin secretion 1/380 12/18722 0.218189233721304 0.392203482516861 IL1B 1 GO:0032736 positive regulation of interleukin-13 production 1/380 12/18722 0.218189233721304 0.392203482516861 HLA-E 1 GO:0032823 regulation of natural killer cell differentiation 1/380 12/18722 0.218189233721304 0.392203482516861 PGLYRP1 1 GO:0032908 regulation of transforming growth factor beta1 production 1/380 12/18722 0.218189233721304 0.392203482516861 TYROBP 1 GO:0033079 immature T cell proliferation 1/380 12/18722 0.218189233721304 0.392203482516861 IL1B 1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 1/380 12/18722 0.218189233721304 0.392203482516861 PELI1 1 GO:0034392 negative regulation of smooth muscle cell apoptotic process 1/380 12/18722 0.218189233721304 0.392203482516861 ARRB2 1 GO:0038180 nerve growth factor signaling pathway 1/380 12/18722 0.218189233721304 0.392203482516861 CORO1A 1 GO:0038203 TORC2 signaling 1/380 12/18722 0.218189233721304 0.392203482516861 RICTOR 1 GO:0042762 regulation of sulfur metabolic process 1/380 12/18722 0.218189233721304 0.392203482516861 NFE2L2 1 GO:0043301 negative regulation of leukocyte degranulation 1/380 12/18722 0.218189233721304 0.392203482516861 SPI1 1 GO:0043383 negative T cell selection 1/380 12/18722 0.218189233721304 0.392203482516861 PTPRC 1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 1/380 12/18722 0.218189233721304 0.392203482516861 PHIP 1 GO:0045916 negative regulation of complement activation 1/380 12/18722 0.218189233721304 0.392203482516861 CD55 1 GO:0051013 microtubule severing 1/380 12/18722 0.218189233721304 0.392203482516861 VPS4B 1 GO:0051340 regulation of ligase activity 1/380 12/18722 0.218189233721304 0.392203482516861 TMSB4X 1 GO:0060019 radial glial cell differentiation 1/380 12/18722 0.218189233721304 0.392203482516861 STAT3 1 GO:0060134 prepulse inhibition 1/380 12/18722 0.218189233721304 0.392203482516861 PTEN 1 GO:0060907 positive regulation of macrophage cytokine production 1/380 12/18722 0.218189233721304 0.392203482516861 LAPTM5 1 GO:0061307 cardiac neural crest cell differentiation involved in heart development 1/380 12/18722 0.218189233721304 0.392203482516861 MAPK1 1 GO:0061308 cardiac neural crest cell development involved in heart development 1/380 12/18722 0.218189233721304 0.392203482516861 MAPK1 1 GO:0061517 macrophage proliferation 1/380 12/18722 0.218189233721304 0.392203482516861 MAPK1 1 GO:0070493 thrombin-activated receptor signaling pathway 1/380 12/18722 0.218189233721304 0.392203482516861 PLEK 1 GO:0070943 neutrophil-mediated killing of symbiont cell 1/380 12/18722 0.218189233721304 0.392203482516861 TREM1 1 GO:0071257 cellular response to electrical stimulus 1/380 12/18722 0.218189233721304 0.392203482516861 PTEN 1 GO:0071287 cellular response to manganese ion 1/380 12/18722 0.218189233721304 0.392203482516861 LRRK2 1 GO:0071472 cellular response to salt stress 1/380 12/18722 0.218189233721304 0.392203482516861 ZFP36L1 1 GO:0071635 negative regulation of transforming growth factor beta production 1/380 12/18722 0.218189233721304 0.392203482516861 TYROBP 1 GO:0072015 glomerular visceral epithelial cell development 1/380 12/18722 0.218189233721304 0.392203482516861 IQGAP1 1 GO:0072537 fibroblast activation 1/380 12/18722 0.218189233721304 0.392203482516861 IL17RA 1 GO:0072584 caveolin-mediated endocytosis 1/380 12/18722 0.218189233721304 0.392203482516861 MAPK1 1 GO:0090385 phagosome-lysosome fusion 1/380 12/18722 0.218189233721304 0.392203482516861 RAB7A 1 GO:0090677 reversible differentiation 1/380 12/18722 0.218189233721304 0.392203482516861 SOD2 1 GO:0097152 mesenchymal cell apoptotic process 1/380 12/18722 0.218189233721304 0.392203482516861 HIF1A 1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 1/380 12/18722 0.218189233721304 0.392203482516861 HSPA1A 1 GO:0098974 postsynaptic actin cytoskeleton organization 1/380 12/18722 0.218189233721304 0.392203482516861 ACTB 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/380 12/18722 0.218189233721304 0.392203482516861 VMP1 1 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance 1/380 12/18722 0.218189233721304 0.392203482516861 PLXNC1 1 GO:1903599 positive regulation of autophagy of mitochondrion 1/380 12/18722 0.218189233721304 0.392203482516861 HIF1A 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/380 12/18722 0.218189233721304 0.392203482516861 DDX5 1 GO:1904748 regulation of apoptotic process involved in development 1/380 12/18722 0.218189233721304 0.392203482516861 TNFRSF1B 1 GO:1905205 positive regulation of connective tissue replacement 1/380 12/18722 0.218189233721304 0.392203482516861 PPP3CA 1 GO:2000009 negative regulation of protein localization to cell surface 1/380 12/18722 0.218189233721304 0.392203482516861 PICALM 1 GO:2000035 regulation of stem cell division 1/380 12/18722 0.218189233721304 0.392203482516861 EVI2B 1 GO:2000508 regulation of dendritic cell chemotaxis 1/380 12/18722 0.218189233721304 0.392203482516861 SPI1 1 GO:2000727 positive regulation of cardiac muscle cell differentiation 1/380 12/18722 0.218189233721304 0.392203482516861 ARRB2 1 GO:2001204 regulation of osteoclast development 1/380 12/18722 0.218189233721304 0.392203482516861 TYROBP 1 GO:0030203 glycosaminoglycan metabolic process 4/380 118/18722 0.218514960180607 0.392455833912159 PGLYRP1/IL1B/IDS/CD44 4 GO:1903313 positive regulation of mRNA metabolic process 4/380 118/18722 0.218514960180607 0.392455833912159 ZFP36/BTG2/ZFP36L1/ZFP36L2 4 GO:0001570 vasculogenesis 3/380 80/18722 0.221557219911141 0.397582553526984 JUNB/ZFP36L1/TGFBR2 3 GO:0048145 regulation of fibroblast proliferation 3/380 80/18722 0.221557219911141 0.397582553526984 FTH1/S100A6/FOSL2 3 GO:0045216 cell-cell junction organization 6/380 200/18722 0.221851340804067 0.397941731598994 CD177/ACTB/IL1B/PECAM1/NUMB/PAK2 6 GO:0035966 response to topologically incorrect protein 5/380 159/18722 0.222204195045173 0.398068851952752 CREBRF/HSPA1A/CUL3/PPP1R15A/NFE2L2 5 GO:0046488 phosphatidylinositol metabolic process 5/380 159/18722 0.222204195045173 0.398068851952752 PLEK/MBOAT7/PTEN/LPGAT1/FAM126B 5 GO:1903169 regulation of calcium ion transmembrane transport 5/380 159/18722 0.222204195045173 0.398068851952752 LYN/CORO1A/CYBA/VMP1/PTPN6 5 GO:0002792 negative regulation of peptide secretion 2/380 44/18722 0.224509005012987 0.401688059243768 MIDN/PPP3CA 2 GO:0046006 regulation of activated T cell proliferation 2/380 44/18722 0.224509005012987 0.401688059243768 PYCARD/PRKAR1A 2 GO:0050999 regulation of nitric-oxide synthase activity 2/380 44/18722 0.224509005012987 0.401688059243768 IL1B/HIF1A 2 GO:0006403 RNA localization 6/380 201/18722 0.225112323326406 0.402597419462554 MX2/ZFP36/ZFP36L1/TGFBR2/NUP214/ZC3H11A 6 GO:0060402 calcium ion transport into cytosol 5/380 160/18722 0.225891490032181 0.403820371585599 PTPRC/LYN/CORO1A/CYBA/PTPN6 5 GO:0000422 autophagy of mitochondrion 3/380 81/18722 0.226902543757603 0.405114786177676 TSPO/BNIP3L/HIF1A 3 GO:0048144 fibroblast proliferation 3/380 81/18722 0.226902543757603 0.405114786177676 FTH1/S100A6/FOSL2 3 GO:0061726 mitochondrion disassembly 3/380 81/18722 0.226902543757603 0.405114786177676 TSPO/BNIP3L/HIF1A 3 GO:0006304 DNA modification 4/380 120/18722 0.22712302385056 0.405166809607043 SPI1/FOS/APOBEC3A/TET2 4 GO:0032411 positive regulation of transporter activity 4/380 120/18722 0.22712302385056 0.405166809607043 CTSS/TMSB4X/VMP1/IFNGR2 4 GO:0048638 regulation of developmental growth 9/380 330/18722 0.229328394056687 0.405928402654294 RGS2/BASP1/PTEN/CXCR4/STK4/STAT3/TGFBR2/PAK1/MAPK1 9 GO:0051650 establishment of vesicle localization 5/380 161/18722 0.229596928157975 0.405928402654294 LRRK2/MYO1F/RAB27A/PICALM/CUL3 5 GO:0001704 formation of primary germ layer 4/380 121/18722 0.23145924831131 0.405928402654294 DUSP1/ITGB2/KDM6B/PRKAR1A 4 GO:0043244 regulation of protein-containing complex disassembly 4/380 121/18722 0.23145924831131 0.405928402654294 PLEK/IRAK3/CAPZA1/TMOD3 4 GO:0003254 regulation of membrane depolarization 2/380 45/18722 0.232022087047978 0.405928402654294 LRRK2/TSPO 2 GO:0006110 regulation of glycolytic process 2/380 45/18722 0.232022087047978 0.405928402654294 STAT3/HIF1A 2 GO:0030835 negative regulation of actin filament depolymerization 2/380 45/18722 0.232022087047978 0.405928402654294 CAPZA1/TMOD3 2 GO:0035305 negative regulation of dephosphorylation 2/380 45/18722 0.232022087047978 0.405928402654294 BOD1L1/PPP1R15A 2 GO:0035384 thioester biosynthetic process 2/380 45/18722 0.232022087047978 0.405928402654294 ACSL1/ELOVL5 2 GO:0045910 negative regulation of DNA recombination 2/380 45/18722 0.232022087047978 0.405928402654294 BCL6/SMCHD1 2 GO:0060421 positive regulation of heart growth 2/380 45/18722 0.232022087047978 0.405928402654294 BASP1/MAPK1 2 GO:0071616 acyl-CoA biosynthetic process 2/380 45/18722 0.232022087047978 0.405928402654294 ACSL1/ELOVL5 2 GO:1901985 positive regulation of protein acetylation 2/380 45/18722 0.232022087047978 0.405928402654294 IL1B/DDX3X 2 GO:1904646 cellular response to amyloid-beta 2/380 45/18722 0.232022087047978 0.405928402654294 NAMPT/FPR2 2 GO:0009205 purine ribonucleoside triphosphate metabolic process 3/380 82/18722 0.232272350324775 0.405928402654294 LRRK2/TMSB4X/STAT3 3 GO:0016575 histone deacetylation 3/380 82/18722 0.232272350324775 0.405928402654294 LRRK2/BCL6/KDM5A 3 GO:0043242 negative regulation of protein-containing complex disassembly 3/380 82/18722 0.232272350324775 0.405928402654294 IRAK3/CAPZA1/TMOD3 3 GO:0021953 central nervous system neuron differentiation 5/380 162/18722 0.233320001617827 0.405928402654294 B2M/BTG2/PTEN/AGTPBP1/NIN 5 GO:0001778 plasma membrane repair 1/380 13/18722 0.234067806205853 0.405928402654294 MYH9 1 GO:0002551 mast cell chemotaxis 1/380 13/18722 0.234067806205853 0.405928402654294 RAC2 1 GO:0002638 negative regulation of immunoglobulin production 1/380 13/18722 0.234067806205853 0.405928402654294 BCL6 1 GO:0003334 keratinocyte development 1/380 13/18722 0.234067806205853 0.405928402654294 FOSL2 1 GO:0006983 ER overload response 1/380 13/18722 0.234067806205853 0.405928402654294 BID 1 GO:0009650 UV protection 1/380 13/18722 0.234067806205853 0.405928402654294 CAT 1 GO:0010917 negative regulation of mitochondrial membrane potential 1/380 13/18722 0.234067806205853 0.405928402654294 BNIP3L 1 GO:0010958 regulation of amino acid import across plasma membrane 1/380 13/18722 0.234067806205853 0.405928402654294 RGS2 1 GO:0015791 polyol transport 1/380 13/18722 0.234067806205853 0.405928402654294 AQP9 1 GO:0015809 arginine transport 1/380 13/18722 0.234067806205853 0.405928402654294 SLC11A1 1 GO:0015816 glycine transport 1/380 13/18722 0.234067806205853 0.405928402654294 RGS2 1 GO:0016078 tRNA catabolic process 1/380 13/18722 0.234067806205853 0.405928402654294 DICER1 1 GO:0019755 one-carbon compound transport 1/380 13/18722 0.234067806205853 0.405928402654294 AQP9 1 GO:0021694 cerebellar Purkinje cell layer formation 1/380 13/18722 0.234067806205853 0.405928402654294 AGTPBP1 1 GO:0021819 layer formation in cerebral cortex 1/380 13/18722 0.234067806205853 0.405928402654294 MBOAT7 1 GO:0030497 fatty acid elongation 1/380 13/18722 0.234067806205853 0.405928402654294 ELOVL5 1 GO:0030836 positive regulation of actin filament depolymerization 1/380 13/18722 0.234067806205853 0.405928402654294 PLEK 1 GO:0031272 regulation of pseudopodium assembly 1/380 13/18722 0.234067806205853 0.405928402654294 CDC42EP3 1 GO:0031274 positive regulation of pseudopodium assembly 1/380 13/18722 0.234067806205853 0.405928402654294 CDC42EP3 1 GO:0032905 transforming growth factor beta1 production 1/380 13/18722 0.234067806205853 0.405928402654294 TYROBP 1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway 1/380 13/18722 0.234067806205853 0.405928402654294 PAK1 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/380 13/18722 0.234067806205853 0.405928402654294 BCL6 1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 1/380 13/18722 0.234067806205853 0.405928402654294 LYN 1 GO:0034982 mitochondrial protein processing 1/380 13/18722 0.234067806205853 0.405928402654294 LRRK2 1 GO:0042492 gamma-delta T cell differentiation 1/380 13/18722 0.234067806205853 0.405928402654294 PTPRC 1 GO:0042761 very long-chain fatty acid biosynthetic process 1/380 13/18722 0.234067806205853 0.405928402654294 ELOVL5 1 GO:0044794 positive regulation by host of viral process 1/380 13/18722 0.234067806205853 0.405928402654294 IGF2R 1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity 1/380 13/18722 0.234067806205853 0.405928402654294 NCF1 1 GO:0048012 hepatocyte growth factor receptor signaling pathway 1/380 13/18722 0.234067806205853 0.405928402654294 PAK1 1 GO:0048207 vesicle targeting, rough ER to cis-Golgi 1/380 13/18722 0.234067806205853 0.405928402654294 CUL3 1 GO:0048208 COPII vesicle coating 1/380 13/18722 0.234067806205853 0.405928402654294 CUL3 1 GO:0048266 behavioral response to pain 1/380 13/18722 0.234067806205853 0.405928402654294 TSPO 1 GO:0048302 regulation of isotype switching to IgG isotypes 1/380 13/18722 0.234067806205853 0.405928402654294 PTPRC 1 GO:0051709 regulation of killing of cells of other organism 1/380 13/18722 0.234067806205853 0.405928402654294 CLEC7A 1 GO:0051956 negative regulation of amino acid transport 1/380 13/18722 0.234067806205853 0.405928402654294 RGS2 1 GO:0061000 negative regulation of dendritic spine development 1/380 13/18722 0.234067806205853 0.405928402654294 PTEN 1 GO:0070254 mucus secretion 1/380 13/18722 0.234067806205853 0.405928402654294 CYBA 1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway 1/380 13/18722 0.234067806205853 0.405928402654294 HSPA1A 1 GO:0072310 glomerular epithelial cell development 1/380 13/18722 0.234067806205853 0.405928402654294 IQGAP1 1 GO:0072393 microtubule anchoring at microtubule organizing center 1/380 13/18722 0.234067806205853 0.405928402654294 NIN 1 GO:1900044 regulation of protein K63-linked ubiquitination 1/380 13/18722 0.234067806205853 0.405928402654294 DDX3X 1 GO:1900121 negative regulation of receptor binding 1/380 13/18722 0.234067806205853 0.405928402654294 B2M 1 GO:1900272 negative regulation of long-term synaptic potentiation 1/380 13/18722 0.234067806205853 0.405928402654294 TYROBP 1 GO:1900452 regulation of long-term synaptic depression 1/380 13/18722 0.234067806205853 0.405928402654294 LILRB2 1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 1/380 13/18722 0.234067806205853 0.405928402654294 PLXNC1 1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 1/380 13/18722 0.234067806205853 0.405928402654294 TMSB4X 1 GO:1903054 negative regulation of extracellular matrix organization 1/380 13/18722 0.234067806205853 0.405928402654294 TNFRSF1B 1 GO:1903789 regulation of amino acid transmembrane transport 1/380 13/18722 0.234067806205853 0.405928402654294 RGS2 1 GO:1905203 regulation of connective tissue replacement 1/380 13/18722 0.234067806205853 0.405928402654294 PPP3CA 1 GO:2001023 regulation of response to drug 1/380 13/18722 0.234067806205853 0.405928402654294 NCOA1 1 GO:0006633 fatty acid biosynthetic process 5/380 163/18722 0.237060201967197 0.410949633782677 PTGS2/ELOVL5/ALOX5/IL1B/LPGAT1 5 GO:0046785 microtubule polymerization 3/380 83/18722 0.23766508083817 0.411829630666796 NIN/HSPA1A/PAK1 3 GO:0060348 bone development 6/380 205/18722 0.238309389707174 0.412777204666618 PTPRC/TYROBP/ALPL/SNX10/TGFBR2/PTPN6 6 GO:0010828 positive regulation of glucose transmembrane transport 2/380 46/18722 0.239550409397688 0.413405046372945 OSBPL8/NFE2L2 2 GO:0034198 cellular response to amino acid starvation 2/380 46/18722 0.239550409397688 0.413405046372945 SH3GLB1/MAPK1 2 GO:0035094 response to nicotine 2/380 46/18722 0.239550409397688 0.413405046372945 B2M/MAPK1 2 GO:0042398 cellular modified amino acid biosynthetic process 2/380 46/18722 0.239550409397688 0.413405046372945 PLSCR1/NFE2L2 2 GO:0043616 keratinocyte proliferation 2/380 46/18722 0.239550409397688 0.413405046372945 ZFP36/ZFP36L1 2 GO:0044818 mitotic G2/M transition checkpoint 2/380 46/18722 0.239550409397688 0.413405046372945 NABP1/NBN 2 GO:0045851 pH reduction 2/380 46/18722 0.239550409397688 0.413405046372945 SLC11A1/RAB7A 2 GO:0090329 regulation of DNA-dependent DNA replication 2/380 46/18722 0.239550409397688 0.413405046372945 BCL6/NBN 2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 2/380 46/18722 0.239550409397688 0.413405046372945 AIF1/DDX3X 2 GO:0071482 cellular response to light stimulus 4/380 123/18722 0.240191962794403 0.414343365553684 PTGS2/CARD16/MME/N4BP1 4 GO:0097061 dendritic spine organization 3/380 84/18722 0.24307919640546 0.417025906958382 LRRK2/PTEN/ACTR2 3 GO:1900542 regulation of purine nucleotide metabolic process 3/380 84/18722 0.24307919640546 0.417025906958382 TMSB4X/STAT3/HIF1A 3 GO:0010632 regulation of epithelial cell migration 8/380 292/18722 0.243302915590781 0.417025906958382 PTGS2/TMSB4X/PTEN/GLUL/TGFBR2/HIF1A/NFE2L2/DOCK5 8 GO:1901988 negative regulation of cell cycle phase transition 7/380 249/18722 0.243333340768729 0.417025906958382 DUSP1/CDKN2D/NABP1/PTEN/ZFP36L1/ZFP36L2/NBN 7 GO:0006417 regulation of translation 12/380 468/18722 0.244166682877614 0.417025906958382 RGS2/ZFP36/VIM/BTG2/ZFP36L1/ZFP36L2/STAT3/EIF1/DDX3X/CPEB4/PPP1R15A/MAPK1 12 GO:0046661 male sex differentiation 5/380 165/18722 0.244589947575946 0.417025906958382 TNFSF10/NCOA1/KDM5A/SF1/NCOA4 5 GO:0001754 eye photoreceptor cell differentiation 2/380 47/18722 0.247090269406171 0.417025906958382 AGTPBP1/STAT3 2 GO:0007595 lactation 2/380 47/18722 0.247090269406171 0.417025906958382 NCOA1/HIF1A 2 GO:0010712 regulation of collagen metabolic process 2/380 47/18722 0.247090269406171 0.417025906958382 VIM/ARRB2 2 GO:0035850 epithelial cell differentiation involved in kidney development 2/380 47/18722 0.247090269406171 0.417025906958382 BASP1/IQGAP1 2 GO:0045601 regulation of endothelial cell differentiation 2/380 47/18722 0.247090269406171 0.417025906958382 IL1B/BTG1 2 GO:0048512 circadian behavior 2/380 47/18722 0.247090269406171 0.417025906958382 PTEN/EGR1 2 GO:0050798 activated T cell proliferation 2/380 47/18722 0.247090269406171 0.417025906958382 PYCARD/PRKAR1A 2 GO:0120163 negative regulation of cold-induced thermogenesis 2/380 47/18722 0.247090269406171 0.417025906958382 TLE3/NRDC 2 GO:0001656 metanephros development 3/380 85/18722 0.24851317851874 0.417025906958382 CXCR2/BASP1/EGR1 3 GO:2000779 regulation of double-strand break repair 3/380 85/18722 0.24851317851874 0.417025906958382 SMCHD1/WAS/ACTR2 3 GO:0018210 peptidyl-threonine modification 4/380 125/18722 0.248999573090399 0.417025906958382 LRRK2/PRKCB/TGFBR2/MAPK1 4 GO:0051053 negative regulation of DNA metabolic process 4/380 125/18722 0.248999573090399 0.417025906958382 BCL6/DUSP1/SMCHD1/NBN 4 GO:0055007 cardiac muscle cell differentiation 4/380 125/18722 0.248999573090399 0.417025906958382 RGS2/KDM6B/ARRB2/PAK1 4 GO:0050808 synapse organization 11/380 426/18722 0.249619000529392 0.417025906958382 SRGN/LRRK2/C5AR1/TUBA1A/ACTB/LILRB2/PTEN/SDCBP/ACTR2/ACTN1/YWHAZ 11 GO:0000212 meiotic spindle organization 1/380 14/18722 0.249624716443801 0.417025906958382 MYH9 1 GO:0001771 immunological synapse formation 1/380 14/18722 0.249624716443801 0.417025906958382 MSN 1 GO:0002091 negative regulation of receptor internalization 1/380 14/18722 0.249624716443801 0.417025906958382 SDCBP 1 GO:0002829 negative regulation of type 2 immune response 1/380 14/18722 0.249624716443801 0.417025906958382 BCL6 1 GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1/380 14/18722 0.249624716443801 0.417025906958382 HLA-E 1 GO:0003214 cardiac left ventricle morphogenesis 1/380 14/18722 0.249624716443801 0.417025906958382 TGFBR2 1 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis 1/380 14/18722 0.249624716443801 0.417025906958382 TGFBR2 1 GO:0009159 deoxyribonucleoside monophosphate catabolic process 1/380 14/18722 0.249624716443801 0.417025906958382 TYMP 1 GO:0010457 centriole-centriole cohesion 1/380 14/18722 0.249624716443801 0.417025906958382 NIN 1 GO:0010896 regulation of triglyceride catabolic process 1/380 14/18722 0.249624716443801 0.417025906958382 SORL1 1 GO:0022038 corpus callosum development 1/380 14/18722 0.249624716443801 0.417025906958382 NIN 1 GO:0030049 muscle filament sliding 1/380 14/18722 0.249624716443801 0.417025906958382 MYL6 1 GO:0030213 hyaluronan biosynthetic process 1/380 14/18722 0.249624716443801 0.417025906958382 IL1B 1 GO:0032688 negative regulation of interferon-beta production 1/380 14/18722 0.249624716443801 0.417025906958382 PYCARD 1 GO:0033008 positive regulation of mast cell activation involved in immune response 1/380 14/18722 0.249624716443801 0.417025906958382 FGR 1 GO:0033169 histone H3-K9 demethylation 1/380 14/18722 0.249624716443801 0.417025906958382 JMJD1C 1 GO:0033212 iron import into cell 1/380 14/18722 0.249624716443801 0.417025906958382 STEAP4 1 GO:0035589 G protein-coupled purinergic nucleotide receptor signaling pathway 1/380 14/18722 0.249624716443801 0.417025906958382 P2RY13 1 GO:0035630 bone mineralization involved in bone maturation 1/380 14/18722 0.249624716443801 0.417025906958382 SNX10 1 GO:0035641 locomotory exploration behavior 1/380 14/18722 0.249624716443801 0.417025906958382 LRRK2 1 GO:0042363 fat-soluble vitamin catabolic process 1/380 14/18722 0.249624716443801 0.417025906958382 CYP4F3 1 GO:0043306 positive regulation of mast cell degranulation 1/380 14/18722 0.249624716443801 0.417025906958382 FGR 1 GO:0043374 CD8-positive, alpha-beta T cell differentiation 1/380 14/18722 0.249624716443801 0.417025906958382 IRF1 1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1/380 14/18722 0.249624716443801 0.417025906958382 DDX5 1 GO:0043558 regulation of translational initiation in response to stress 1/380 14/18722 0.249624716443801 0.417025906958382 PPP1R15A 1 GO:0045006 DNA deamination 1/380 14/18722 0.249624716443801 0.417025906958382 APOBEC3A 1 GO:0045059 positive thymic T cell selection 1/380 14/18722 0.249624716443801 0.417025906958382 PTPRC 1 GO:0045820 negative regulation of glycolytic process 1/380 14/18722 0.249624716443801 0.417025906958382 STAT3 1 GO:0045837 negative regulation of membrane potential 1/380 14/18722 0.249624716443801 0.417025906958382 BNIP3L 1 GO:0045989 positive regulation of striated muscle contraction 1/380 14/18722 0.249624716443801 0.417025906958382 RGS2 1 GO:0046325 negative regulation of glucose import 1/380 14/18722 0.249624716443801 0.417025906958382 STXBP3 1 GO:0046348 amino sugar catabolic process 1/380 14/18722 0.249624716443801 0.417025906958382 CTBS 1 GO:0047484 regulation of response to osmotic stress 1/380 14/18722 0.249624716443801 0.417025906958382 PTGS2 1 GO:0048291 isotype switching to IgG isotypes 1/380 14/18722 0.249624716443801 0.417025906958382 PTPRC 1 GO:0048681 negative regulation of axon regeneration 1/380 14/18722 0.249624716443801 0.417025906958382 PTEN 1 GO:0050930 induction of positive chemotaxis 1/380 14/18722 0.249624716443801 0.417025906958382 CXCL8 1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 1/380 14/18722 0.249624716443801 0.417025906958382 CXCR4 1 GO:0051547 regulation of keratinocyte migration 1/380 14/18722 0.249624716443801 0.417025906958382 PTEN 1 GO:0051645 Golgi localization 1/380 14/18722 0.249624716443801 0.417025906958382 YWHAZ 1 GO:0055057 neuroblast division 1/380 14/18722 0.249624716443801 0.417025906958382 NUMB 1 GO:0060081 membrane hyperpolarization 1/380 14/18722 0.249624716443801 0.417025906958382 SOD2 1 GO:0060354 negative regulation of cell adhesion molecule production 1/380 14/18722 0.249624716443801 0.417025906958382 CXCL8 1 GO:0060576 intestinal epithelial cell development 1/380 14/18722 0.249624716443801 0.417025906958382 HIF1A 1 GO:0070141 response to UV-A 1/380 14/18722 0.249624716443801 0.417025906958382 MME 1 GO:0070278 extracellular matrix constituent secretion 1/380 14/18722 0.249624716443801 0.417025906958382 TNFRSF1B 1 GO:0070307 lens fiber cell development 1/380 14/18722 0.249624716443801 0.417025906958382 VIM 1 GO:0070942 neutrophil mediated cytotoxicity 1/380 14/18722 0.249624716443801 0.417025906958382 TREM1 1 GO:0071236 cellular response to antibiotic 1/380 14/18722 0.249624716443801 0.417025906958382 ACTR2 1 GO:0072531 pyrimidine-containing compound transmembrane transport 1/380 14/18722 0.249624716443801 0.417025906958382 AQP9 1 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 1/380 14/18722 0.249624716443801 0.417025906958382 RGS2 1 GO:0090128 regulation of synapse maturation 1/380 14/18722 0.249624716443801 0.417025906958382 YWHAZ 1 GO:0097091 synaptic vesicle clustering 1/380 14/18722 0.249624716443801 0.417025906958382 PTEN 1 GO:0097531 mast cell migration 1/380 14/18722 0.249624716443801 0.417025906958382 RAC2 1 GO:0099188 postsynaptic cytoskeleton organization 1/380 14/18722 0.249624716443801 0.417025906958382 ACTB 1 GO:0099638 endosome to plasma membrane protein transport 1/380 14/18722 0.249624716443801 0.417025906958382 RAB7A 1 GO:1901857 positive regulation of cellular respiration 1/380 14/18722 0.249624716443801 0.417025906958382 IFNAR1 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/380 14/18722 0.249624716443801 0.417025906958382 CD44 1 GO:1902969 mitotic DNA replication 1/380 14/18722 0.249624716443801 0.417025906958382 BCL6 1 GO:1904294 positive regulation of ERAD pathway 1/380 14/18722 0.249624716443801 0.417025906958382 NFE2L2 1 GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation 1/380 14/18722 0.249624716443801 0.417025906958382 SOD2 1 GO:1903034 regulation of response to wounding 5/380 167/18722 0.252182092277843 0.421132161197424 ALOX5/PTEN/CXCR4/CLEC7A/NFE2L2 5 GO:0045017 glycerolipid biosynthetic process 7/380 252/18722 0.252497512438652 0.421492694196961 ACSL1/MBOAT7/PTEN/LPGAT1/FAM126B/LPCAT2/PLSCR1 7 GO:0046928 regulation of neurotransmitter secretion 3/380 86/18722 0.253965529515055 0.423609301889035 LRRK2/PRKCB/MCTP2 3 GO:0048864 stem cell development 3/380 86/18722 0.253965529515055 0.423609301889035 PTPRC/HIF1A/MAPK1 3 GO:0033628 regulation of cell adhesion mediated by integrin 2/380 48/18722 0.254638107684543 0.423729817699033 LYN/PTPN6 2 GO:0048146 positive regulation of fibroblast proliferation 2/380 48/18722 0.254638107684543 0.423729817699033 S100A6/FOSL2 2 GO:0097720 calcineurin-mediated signaling 2/380 48/18722 0.254638107684543 0.423729817699033 CLEC7A/PPP3CA 2 GO:0120009 intermembrane lipid transfer 2/380 48/18722 0.254638107684543 0.423729817699033 TSPO/OSBPL8 2 GO:1903053 regulation of extracellular matrix organization 2/380 48/18722 0.254638107684543 0.423729817699033 CFLAR/TNFRSF1B 2 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 2/380 48/18722 0.254638107684543 0.423729817699033 SDCBP/N4BP1 2 GO:0009165 nucleotide biosynthetic process 7/380 254/18722 0.258664160860264 0.428546175935473 NAMPT/ACSL1/TMSB4X/ELOVL5/STAT3/NADK/MAPK1 7 GO:0019915 lipid storage 3/380 87/18722 0.259434772996942 0.428546175935473 FFAR2/IL1B/OSBPL8 3 GO:0044070 regulation of anion transport 3/380 87/18722 0.259434772996942 0.428546175935473 RGS2/CEBPB/IL1B 3 GO:0048041 focal adhesion assembly 3/380 87/18722 0.259434772996942 0.428546175935473 PTEN/IQGAP1/ACTN1 3 GO:1900182 positive regulation of protein localization to nucleus 3/380 87/18722 0.259434772996942 0.428546175935473 PTGS2/HCLS1/MAPK1 3 GO:1901879 regulation of protein depolymerization 3/380 87/18722 0.259434772996942 0.428546175935473 PLEK/CAPZA1/TMOD3 3 GO:0001667 ameboidal-type cell migration 12/380 475/18722 0.259729496031119 0.428546175935473 PTGS2/TMSB4X/ARHGDIB/PTEN/GLUL/CAP1/TGFBR2/HIF1A/MYH9/PAK1/NFE2L2/DOCK5 12 GO:0048511 rhythmic process 8/380 298/18722 0.260261647315631 0.428546175935473 NAMPT/ARRB2/PTEN/EGR1/NFIL3/NCOA1/DDX5/KDM5A 8 GO:0006376 mRNA splice site selection 2/380 49/18722 0.262190503846658 0.428546175935473 CELF2/SF1 2 GO:0006692 prostanoid metabolic process 2/380 49/18722 0.262190503846658 0.428546175935473 PTGS2/IL1B 2 GO:0006693 prostaglandin metabolic process 2/380 49/18722 0.262190503846658 0.428546175935473 PTGS2/IL1B 2 GO:0007622 rhythmic behavior 2/380 49/18722 0.262190503846658 0.428546175935473 PTEN/EGR1 2 GO:0008038 neuron recognition 2/380 49/18722 0.262190503846658 0.428546175935473 CXCR4/YWHAZ 2 GO:0009409 response to cold 2/380 49/18722 0.262190503846658 0.428546175935473 SOD2/FOS 2 GO:0014075 response to amine 2/380 49/18722 0.262190503846658 0.428546175935473 RGS2/PPP3CA 2 GO:0032692 negative regulation of interleukin-1 production 2/380 49/18722 0.262190503846658 0.428546175935473 ARRB2/CARD16 2 GO:0043457 regulation of cellular respiration 2/380 49/18722 0.262190503846658 0.428546175935473 HIF1A/IFNAR1 2 GO:0046580 negative regulation of Ras protein signal transduction 2/380 49/18722 0.262190503846658 0.428546175935473 BCL6/CUL3 2 GO:0070169 positive regulation of biomineral tissue development 2/380 49/18722 0.262190503846658 0.428546175935473 ALOX5/CEBPB 2 GO:0072091 regulation of stem cell proliferation 2/380 49/18722 0.262190503846658 0.428546175935473 PTPRC/ZFP36L1 2 GO:1901799 negative regulation of proteasomal protein catabolic process 2/380 49/18722 0.262190503846658 0.428546175935473 SDCBP/N4BP1 2 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 2/380 49/18722 0.262190503846658 0.428546175935473 NQO2/PAK1 2 GO:1990928 response to amino acid starvation 2/380 49/18722 0.262190503846658 0.428546175935473 SH3GLB1/MAPK1 2 GO:0001325 formation of extrachromosomal circular DNA 1/380 15/18722 0.264866463704404 0.428546175935473 NBN 1 GO:0002070 epithelial cell maturation 1/380 15/18722 0.264866463704404 0.428546175935473 HIF1A 1 GO:0002730 regulation of dendritic cell cytokine production 1/380 15/18722 0.264866463704404 0.428546175935473 CLEC7A 1 GO:0006089 lactate metabolic process 1/380 15/18722 0.264866463704404 0.428546175935473 HIF1A 1 GO:0006098 pentose-phosphate shunt 1/380 15/18722 0.264866463704404 0.428546175935473 TALDO1 1 GO:0006825 copper ion transport 1/380 15/18722 0.264866463704404 0.428546175935473 STEAP4 1 GO:0010763 positive regulation of fibroblast migration 1/380 15/18722 0.264866463704404 0.428546175935473 PAK1 1 GO:0010889 regulation of sequestering of triglyceride 1/380 15/18722 0.264866463704404 0.428546175935473 OSBPL8 1 GO:0010940 positive regulation of necrotic cell death 1/380 15/18722 0.264866463704404 0.428546175935473 TSPO 1 GO:0014733 regulation of skeletal muscle adaptation 1/380 15/18722 0.264866463704404 0.428546175935473 PPP3CA 1 GO:0018410 C-terminal protein amino acid modification 1/380 15/18722 0.264866463704404 0.428546175935473 AGTPBP1 1 GO:0019511 peptidyl-proline hydroxylation 1/380 15/18722 0.264866463704404 0.428546175935473 EGLN1 1 GO:0031269 pseudopodium assembly 1/380 15/18722 0.264866463704404 0.428546175935473 CDC42EP3 1 GO:0032310 prostaglandin secretion 1/380 15/18722 0.264866463704404 0.428546175935473 IL1B 1 GO:0032488 Cdc42 protein signal transduction 1/380 15/18722 0.264866463704404 0.428546175935473 WAS 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/380 15/18722 0.264866463704404 0.428546175935473 IL1B 1 GO:0033275 actin-myosin filament sliding 1/380 15/18722 0.264866463704404 0.428546175935473 MYL6 1 GO:0042976 activation of Janus kinase activity 1/380 15/18722 0.264866463704404 0.428546175935473 IL6R 1 GO:0042994 cytoplasmic sequestering of transcription factor 1/380 15/18722 0.264866463704404 0.428546175935473 TMSB4X 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/380 15/18722 0.264866463704404 0.428546175935473 CD44 1 GO:0043584 nose development 1/380 15/18722 0.264866463704404 0.428546175935473 SMCHD1 1 GO:0045064 T-helper 2 cell differentiation 1/380 15/18722 0.264866463704404 0.428546175935473 BCL6 1 GO:0045176 apical protein localization 1/380 15/18722 0.264866463704404 0.428546175935473 ACTB 1 GO:0045217 cell-cell junction maintenance 1/380 15/18722 0.264866463704404 0.428546175935473 CD177 1 GO:0045836 positive regulation of meiotic nuclear division 1/380 15/18722 0.264866463704404 0.428546175935473 UBE2B 1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition 1/380 15/18722 0.264866463704404 0.428546175935473 CUL3 1 GO:0046007 negative regulation of activated T cell proliferation 1/380 15/18722 0.264866463704404 0.428546175935473 PRKAR1A 1 GO:0051127 positive regulation of actin nucleation 1/380 15/18722 0.264866463704404 0.428546175935473 WAS 1 GO:0051608 histamine transport 1/380 15/18722 0.264866463704404 0.428546175935473 LYN 1 GO:0051775 response to redox state 1/380 15/18722 0.264866463704404 0.428546175935473 ARHGDIB 1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum 1/380 15/18722 0.264866463704404 0.428546175935473 SORL1 1 GO:0072075 metanephric mesenchyme development 1/380 15/18722 0.264866463704404 0.428546175935473 BASP1 1 GO:0072224 metanephric glomerulus development 1/380 15/18722 0.264866463704404 0.428546175935473 EGR1 1 GO:0080154 regulation of fertilization 1/380 15/18722 0.264866463704404 0.428546175935473 MYH9 1 GO:0090656 t-circle formation 1/380 15/18722 0.264866463704404 0.428546175935473 NBN 1 GO:0090737 telomere maintenance via telomere trimming 1/380 15/18722 0.264866463704404 0.428546175935473 NBN 1 GO:0099170 postsynaptic modulation of chemical synaptic transmission 1/380 15/18722 0.264866463704404 0.428546175935473 PPP3CA 1 GO:0110156 methylguanosine-cap decapping 1/380 15/18722 0.264866463704404 0.428546175935473 ZFP36 1 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 1/380 15/18722 0.264866463704404 0.428546175935473 PPP1R15A 1 GO:1901741 positive regulation of myoblast fusion 1/380 15/18722 0.264866463704404 0.428546175935473 CD53 1 GO:1901970 positive regulation of mitotic sister chromatid separation 1/380 15/18722 0.264866463704404 0.428546175935473 CUL3 1 GO:1902902 negative regulation of autophagosome assembly 1/380 15/18722 0.264866463704404 0.428546175935473 LRRK2 1 GO:1904424 regulation of GTP binding 1/380 15/18722 0.264866463704404 0.428546175935473 CCPG1 1 GO:2000104 negative regulation of DNA-dependent DNA replication 1/380 15/18722 0.264866463704404 0.428546175935473 BCL6 1 GO:2000345 regulation of hepatocyte proliferation 1/380 15/18722 0.264866463704404 0.428546175935473 CFLAR 1 GO:2001028 positive regulation of endothelial cell chemotaxis 1/380 15/18722 0.264866463704404 0.428546175935473 TMSB4X 1 GO:1901293 nucleoside phosphate biosynthetic process 7/380 256/18722 0.26487414934692 0.428546175935473 NAMPT/ACSL1/TMSB4X/ELOVL5/STAT3/NADK/MAPK1 7 GO:0009144 purine nucleoside triphosphate metabolic process 3/380 88/18722 0.264919454214656 0.428546175935473 LRRK2/TMSB4X/STAT3 3 GO:0031110 regulation of microtubule polymerization or depolymerization 3/380 88/18722 0.264919454214656 0.428546175935473 NIN/HSPA1A/PAK1 3 GO:1901657 glycosyl compound metabolic process 3/380 88/18722 0.264919454214656 0.428546175935473 CDA/APOBEC3A/TYMP 3 GO:0001505 regulation of neurotransmitter levels 6/380 213/18722 0.265366216885794 0.429104974612958 LRRK2/PRKCB/AGTPBP1/STX3/MCTP2/STXBP3 6 GO:0007498 mesoderm development 4/380 129/18722 0.266813549962291 0.431280680950497 HCK/KDM6B/ZFP36L1/PRKAR1A 4 GO:0048469 cell maturation 5/380 171/18722 0.26753730609826 0.432285574714281 LRRK2/KLF2/CLEC7A/PTBP3/HIF1A 5 GO:0002639 positive regulation of immunoglobulin production 2/380 50/18722 0.269744172358132 0.433865009470827 PTPRC/HLA-E 2 GO:0007080 mitotic metaphase plate congression 2/380 50/18722 0.269744172358132 0.433865009470827 CUL3/VPS4B 2 GO:0019083 viral transcription 2/380 50/18722 0.269744172358132 0.433865009470827 ZFP36/IFITM3 2 GO:0045814 negative regulation of gene expression, epigenetic 2/380 50/18722 0.269744172358132 0.433865009470827 SPI1/SMCHD1 2 GO:0046460 neutral lipid biosynthetic process 2/380 50/18722 0.269744172358132 0.433865009470827 ACSL1/LPGAT1 2 GO:0046463 acylglycerol biosynthetic process 2/380 50/18722 0.269744172358132 0.433865009470827 ACSL1/LPGAT1 2 GO:0046638 positive regulation of alpha-beta T cell differentiation 2/380 50/18722 0.269744172358132 0.433865009470827 NFKBIZ/TGFBR2 2 GO:0060425 lung morphogenesis 2/380 50/18722 0.269744172358132 0.433865009470827 TGFBR2/MAPK1 2 GO:0070231 T cell apoptotic process 2/380 50/18722 0.269744172358132 0.433865009470827 TSC22D3/HIF1A 2 GO:0099054 presynapse assembly 2/380 50/18722 0.269744172358132 0.433865009470827 PTEN/SDCBP 2 GO:0110151 positive regulation of biomineralization 2/380 50/18722 0.269744172358132 0.433865009470827 ALOX5/CEBPB 2 GO:1904036 negative regulation of epithelial cell apoptotic process 2/380 50/18722 0.269744172358132 0.433865009470827 CFLAR/NFE2L2 2 GO:0009199 ribonucleoside triphosphate metabolic process 3/380 89/18722 0.270418140411729 0.434783912165404 LRRK2/TMSB4X/STAT3 3 GO:0007059 chromosome segregation 9/380 346/18722 0.271322963439187 0.435880205318875 DUSP1/ACTR2/PLSCR1/ACTR3/UBE2B/STAG2/DDX3X/CUL3/VPS4B 9 GO:0001678 cellular glucose homeostasis 5/380 172/18722 0.271408760667267 0.435880205318875 CYBA/NADK/HIF1A/STXBP3/PPP3CA 5 GO:0042770 signal transduction in response to DNA damage 5/380 172/18722 0.271408760667267 0.435880205318875 CD44/BID/USP10/DDX5/NBN 5 GO:0048732 gland development 11/380 436/18722 0.273302891578579 0.438755779315876 CEBPB/CFLAR/TSPO/PTEN/MSN/IGF2R/TGFBR2/NCOA1/HIF1A/CUL3/MAPK1 11 GO:0006694 steroid biosynthetic process 5/380 173/18722 0.275292265393288 0.438870565902552 TSPO/EGR1/HSD17B11/LBR/SF1 5 GO:0051099 positive regulation of binding 5/380 173/18722 0.275292265393288 0.438870565902552 LRRK2/B2M/PLAUR/STK4/RALB 5 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 4/380 131/18722 0.27580712825092 0.438870565902552 SORL1/UBE2D1/UBE2D3/HSPA1A 4 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 4/380 131/18722 0.27580712825092 0.438870565902552 LRG1/CFLAR/SDCBP/HSPA1A 4 GO:0046849 bone remodeling 3/380 90/18722 0.275929421135415 0.438870565902552 RAC2/RASSF2/SNX10 3 GO:0061097 regulation of protein tyrosine kinase activity 3/380 90/18722 0.275929421135415 0.438870565902552 PTPRC/NCF1/PAK2 3 GO:0032964 collagen biosynthetic process 2/380 51/18722 0.277295958495889 0.438870565902552 VIM/ARRB2 2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 2/380 51/18722 0.277295958495889 0.438870565902552 PYCARD/USP10 2 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 2/380 51/18722 0.277295958495889 0.438870565902552 BCL6/NFKBIZ 2 GO:0048013 ephrin receptor signaling pathway 2/380 51/18722 0.277295958495889 0.438870565902552 LYN/PAK1 2 GO:0051339 regulation of lyase activity 2/380 51/18722 0.277295958495889 0.438870565902552 P2RY13/CAP1 2 GO:0048639 positive regulation of developmental growth 5/380 174/18722 0.27918731738451 0.438870565902552 BASP1/CXCR4/TGFBR2/PAK1/MAPK1 5 GO:0001574 ganglioside biosynthetic process 1/380 16/18722 0.279799416277897 0.438870565902552 ST8SIA4 1 GO:0001977 renal system process involved in regulation of blood volume 1/380 16/18722 0.279799416277897 0.438870565902552 CYBA 1 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 1/380 16/18722 0.279799416277897 0.438870565902552 MME 1 GO:0002371 dendritic cell cytokine production 1/380 16/18722 0.279799416277897 0.438870565902552 CLEC7A 1 GO:0002399 MHC class II protein complex assembly 1/380 16/18722 0.279799416277897 0.438870565902552 B2M 1 GO:0002503 peptide antigen assembly with MHC class II protein complex 1/380 16/18722 0.279799416277897 0.438870565902552 B2M 1 GO:0002566 somatic diversification of immune receptors via somatic mutation 1/380 16/18722 0.279799416277897 0.438870565902552 ADAR 1 GO:0003084 positive regulation of systemic arterial blood pressure 1/380 16/18722 0.279799416277897 0.438870565902552 CYBA 1 GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 1/380 16/18722 0.279799416277897 0.438870565902552 TGFBR2 1 GO:0005980 glycogen catabolic process 1/380 16/18722 0.279799416277897 0.438870565902552 PYGL 1 GO:0006740 NADPH regeneration 1/380 16/18722 0.279799416277897 0.438870565902552 TALDO1 1 GO:0006750 glutathione biosynthetic process 1/380 16/18722 0.279799416277897 0.438870565902552 NFE2L2 1 GO:0006828 manganese ion transport 1/380 16/18722 0.279799416277897 0.438870565902552 SLC11A1 1 GO:0009048 dosage compensation by inactivation of X chromosome 1/380 16/18722 0.279799416277897 0.438870565902552 SMCHD1 1 GO:0009111 vitamin catabolic process 1/380 16/18722 0.279799416277897 0.438870565902552 CYP4F3 1 GO:0009642 response to light intensity 1/380 16/18722 0.279799416277897 0.438870565902552 CAT 1 GO:0010225 response to UV-C 1/380 16/18722 0.279799416277897 0.438870565902552 CARD16 1 GO:0010919 regulation of inositol phosphate biosynthetic process 1/380 16/18722 0.279799416277897 0.438870565902552 PLEK 1 GO:0030575 nuclear body organization 1/380 16/18722 0.279799416277897 0.438870565902552 SF1 1 GO:0031268 pseudopodium organization 1/380 16/18722 0.279799416277897 0.438870565902552 CDC42EP3 1 GO:0034138 toll-like receptor 3 signaling pathway 1/380 16/18722 0.279799416277897 0.438870565902552 PELI1 1 GO:0035751 regulation of lysosomal lumen pH 1/380 16/18722 0.279799416277897 0.438870565902552 LRRK2 1 GO:0035970 peptidyl-threonine dephosphorylation 1/380 16/18722 0.279799416277897 0.438870565902552 DUSP1 1 GO:0045838 positive regulation of membrane potential 1/380 16/18722 0.279799416277897 0.438870565902552 BID 1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 1/380 16/18722 0.279799416277897 0.438870565902552 APOBEC3A 1 GO:0048311 mitochondrion distribution 1/380 16/18722 0.279799416277897 0.438870565902552 LRRK2 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/380 16/18722 0.279799416277897 0.438870565902552 KLF2 1 GO:0051969 regulation of transmission of nerve impulse 1/380 16/18722 0.279799416277897 0.438870565902552 TYMP 1 GO:0070242 thymocyte apoptotic process 1/380 16/18722 0.279799416277897 0.438870565902552 HIF1A 1 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1/380 16/18722 0.279799416277897 0.438870565902552 HSPA1A 1 GO:0070571 negative regulation of neuron projection regeneration 1/380 16/18722 0.279799416277897 0.438870565902552 PTEN 1 GO:0071391 cellular response to estrogen stimulus 1/380 16/18722 0.279799416277897 0.438870565902552 NCOA4 1 GO:0071732 cellular response to nitric oxide 1/380 16/18722 0.279799416277897 0.438870565902552 CFLAR 1 GO:0090231 regulation of spindle checkpoint 1/380 16/18722 0.279799416277897 0.438870565902552 DUSP1 1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 1/380 16/18722 0.279799416277897 0.438870565902552 DUSP1 1 GO:0090336 positive regulation of brown fat cell differentiation 1/380 16/18722 0.279799416277897 0.438870565902552 PTGS2 1 GO:0098884 postsynaptic neurotransmitter receptor internalization 1/380 16/18722 0.279799416277897 0.438870565902552 NUMB 1 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane 1/380 16/18722 0.279799416277897 0.438870565902552 STX3 1 GO:0140239 postsynaptic endocytosis 1/380 16/18722 0.279799416277897 0.438870565902552 NUMB 1 GO:1901163 regulation of trophoblast cell migration 1/380 16/18722 0.279799416277897 0.438870565902552 ARHGDIB 1 GO:1902101 positive regulation of metaphase/anaphase transition of cell cycle 1/380 16/18722 0.279799416277897 0.438870565902552 CUL3 1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/380 16/18722 0.279799416277897 0.438870565902552 CD44 1 GO:1902570 protein localization to nucleolus 1/380 16/18722 0.279799416277897 0.438870565902552 GLUL 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/380 16/18722 0.279799416277897 0.438870565902552 PLEK 1 GO:1903504 regulation of mitotic spindle checkpoint 1/380 16/18722 0.279799416277897 0.438870565902552 DUSP1 1 GO:1905874 regulation of postsynaptic density organization 1/380 16/18722 0.279799416277897 0.438870565902552 LILRB2 1 GO:2000765 regulation of cytoplasmic translation 1/380 16/18722 0.279799416277897 0.438870565902552 CPEB4 1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining 1/380 16/18722 0.279799416277897 0.438870565902552 SMCHD1 1 GO:2001044 regulation of integrin-mediated signaling pathway 1/380 16/18722 0.279799416277897 0.438870565902552 CD177 1 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/380 16/18722 0.279799416277897 0.438870565902552 PLAUR 1 GO:0006310 DNA recombination 8/380 305/18722 0.280482009192316 0.439714638507408 PTPRC/BCL6/SMCHD1/WAS/NABP1/ACTR2/UBE2B/NBN 8 GO:0000280 nuclear division 11/380 439/18722 0.28054520737828 0.439714638507408 DUSP1/IL1B/ACTR2/PRKAR1A/ACTR3/UBE2B/STAG2/HSPA1A/CUL3/VPS4B/PHIP 11 GO:0019935 cyclic-nucleotide-mediated signaling 3/380 91/18722 0.281451908513544 0.44080947949514 RGS2/CAP1/UBE2B 3 GO:0051983 regulation of chromosome segregation 3/380 91/18722 0.281451908513544 0.44080947949514 DUSP1/PLSCR1/CUL3 3 GO:0048771 tissue remodeling 5/380 175/18722 0.283093415296301 0.443216493079422 RAC2/RASSF2/SNX10/HIF1A/PPP3CA 5 GO:0006650 glycerophospholipid metabolic process 8/380 306/18722 0.283405108037212 0.443540514611083 PLEK/MBOAT7/PTEN/LPGAT1/FAM126B/LPCAT2/OSBPL8/PLSCR1 8 GO:0031103 axon regeneration 2/380 52/18722 0.284842834415461 0.444815611702303 TSPO/PTEN 2 GO:0032206 positive regulation of telomere maintenance 2/380 52/18722 0.284842834415461 0.444815611702303 MAPK1/NBN 2 GO:0043392 negative regulation of DNA binding 2/380 52/18722 0.284842834415461 0.444815611702303 TMSB4X/IFI16 2 GO:0048260 positive regulation of receptor-mediated endocytosis 2/380 52/18722 0.284842834415461 0.444815611702303 B2M/ARRB2 2 GO:0051496 positive regulation of stress fiber assembly 2/380 52/18722 0.284842834415461 0.444815611702303 GPR65/PAK1 2 GO:0010595 positive regulation of endothelial cell migration 4/380 133/18722 0.284850044613139 0.444815611702303 PTGS2/TMSB4X/HIF1A/NFE2L2 4 GO:0003018 vascular process in circulatory system 7/380 263/18722 0.286920217715489 0.447363857906142 SOD2/PTGS2/RGS2/CXCR2/SLC2A3/KLF2/DOCK5 7 GO:0031058 positive regulation of histone modification 3/380 92/18722 0.286984237499265 0.447363857906142 LRRK2/BCL6/IL1B 3 GO:0035249 synaptic transmission, glutamatergic 3/380 92/18722 0.286984237499265 0.447363857906142 PTGS2/LRRK2/GLUL 3 GO:1903351 cellular response to dopamine 3/380 92/18722 0.286984237499265 0.447363857906142 LRRK2/ARRB2/MAPK1 3 GO:0043534 blood vessel endothelial cell migration 5/380 176/18722 0.287010059487836 0.447363857906142 PTGS2/TMSB4X/HIF1A/MYH9/NFE2L2 5 GO:0032147 activation of protein kinase activity 4/380 134/18722 0.289388070763792 0.448690270870239 SLC11A1/IL6R/OSBPL8/TGFBR2 4 GO:0048285 organelle fission 12/380 488/18722 0.289500059981354 0.448690270870239 LRRK2/DUSP1/IL1B/ACTR2/PRKAR1A/ACTR3/UBE2B/STAG2/HSPA1A/CUL3/VPS4B/PHIP 12 GO:0030324 lung development 5/380 177/18722 0.290936752174773 0.448690270870239 KLF2/TGFBR2/YWHAZ/MME/MAPK1 5 GO:0001541 ovarian follicle development 2/380 53/18722 0.29238189532337 0.448690270870239 CEBPB/ARRB2 2 GO:0008347 glial cell migration 2/380 53/18722 0.29238189532337 0.448690270870239 MBOAT7/TSPO 2 GO:0031279 regulation of cyclase activity 2/380 53/18722 0.29238189532337 0.448690270870239 P2RY13/CAP1 2 GO:0033059 cellular pigmentation 2/380 53/18722 0.29238189532337 0.448690270870239 LYST/RAB27A 2 GO:0045806 negative regulation of endocytosis 2/380 53/18722 0.29238189532337 0.448690270870239 SDCBP/PICALM 2 GO:0071320 cellular response to cAMP 2/380 53/18722 0.29238189532337 0.448690270870239 AQP9/ZFP36L1 2 GO:0007589 body fluid secretion 3/380 93/18722 0.292525066085074 0.448690270870239 CYBA/NCOA1/HIF1A 3 GO:0045132 meiotic chromosome segregation 3/380 93/18722 0.292525066085074 0.448690270870239 ACTR2/ACTR3/UBE2B 3 GO:0106027 neuron projection organization 3/380 93/18722 0.292525066085074 0.448690270870239 LRRK2/PTEN/ACTR2 3 GO:1903350 response to dopamine 3/380 93/18722 0.292525066085074 0.448690270870239 LRRK2/ARRB2/MAPK1 3 GO:0006091 generation of precursor metabolites and energy 12/380 490/18722 0.294169752236195 0.448690270870239 NCF1/STEAP4/NCF2/PYGL/CYBA/STAT3/BID/TALDO1/NQO2/HIF1A/IFNAR1/CAT 12 GO:0002031 G protein-coupled receptor internalization 1/380 17/18722 0.29442981410824 0.448690270870239 ARRB2 1 GO:0006901 vesicle coating 1/380 17/18722 0.29442981410824 0.448690270870239 CUL3 1 GO:0007351 tripartite regional subdivision 1/380 17/18722 0.29442981410824 0.448690270870239 BASP1 1 GO:0008340 determination of adult lifespan 1/380 17/18722 0.29442981410824 0.448690270870239 LRRK2 1 GO:0008595 anterior/posterior axis specification, embryo 1/380 17/18722 0.29442981410824 0.448690270870239 BASP1 1 GO:0009084 glutamine family amino acid biosynthetic process 1/380 17/18722 0.29442981410824 0.448690270870239 GLUL 1 GO:0010224 response to UV-B 1/380 17/18722 0.29442981410824 0.448690270870239 MME 1 GO:0010566 regulation of ketone biosynthetic process 1/380 17/18722 0.29442981410824 0.448690270870239 EGR1 1 GO:0010612 regulation of cardiac muscle adaptation 1/380 17/18722 0.29442981410824 0.448690270870239 PPP3CA 1 GO:0016264 gap junction assembly 1/380 17/18722 0.29442981410824 0.448690270870239 IL1B 1 GO:0021692 cerebellar Purkinje cell layer morphogenesis 1/380 17/18722 0.29442981410824 0.448690270870239 AGTPBP1 1 GO:0021756 striatum development 1/380 17/18722 0.29442981410824 0.448690270870239 LRRK2 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/380 17/18722 0.29442981410824 0.448690270870239 TMEM50A 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/380 17/18722 0.29442981410824 0.448690270870239 IL1B 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/380 17/18722 0.29442981410824 0.448690270870239 IL1B 1 GO:0033623 regulation of integrin activation 1/380 17/18722 0.29442981410824 0.448690270870239 PLEK 1 GO:0034349 glial cell apoptotic process 1/380 17/18722 0.29442981410824 0.448690270870239 BID 1 GO:0035855 megakaryocyte development 1/380 17/18722 0.29442981410824 0.448690270870239 PTPN6 1 GO:0036035 osteoclast development 1/380 17/18722 0.29442981410824 0.448690270870239 TYROBP 1 GO:0036166 phenotypic switching 1/380 17/18722 0.29442981410824 0.448690270870239 SOD2 1 GO:0042053 regulation of dopamine metabolic process 1/380 17/18722 0.29442981410824 0.448690270870239 ITGB2 1 GO:0042069 regulation of catecholamine metabolic process 1/380 17/18722 0.29442981410824 0.448690270870239 ITGB2 1 GO:0042448 progesterone metabolic process 1/380 17/18722 0.29442981410824 0.448690270870239 EGR1 1 GO:0043117 positive regulation of vascular permeability 1/380 17/18722 0.29442981410824 0.448690270870239 CXCR2 1 GO:0043649 dicarboxylic acid catabolic process 1/380 17/18722 0.29442981410824 0.448690270870239 GLUL 1 GO:0044539 long-chain fatty acid import into cell 1/380 17/18722 0.29442981410824 0.448690270870239 ACSL1 1 GO:0045198 establishment of epithelial cell apical/basal polarity 1/380 17/18722 0.29442981410824 0.448690270870239 MSN 1 GO:0046827 positive regulation of protein export from nucleus 1/380 17/18722 0.29442981410824 0.448690270870239 IL1B 1 GO:0046855 inositol phosphate dephosphorylation 1/380 17/18722 0.29442981410824 0.448690270870239 PTEN 1 GO:0055119 relaxation of cardiac muscle 1/380 17/18722 0.29442981410824 0.448690270870239 RGS2 1 GO:0060033 anatomical structure regression 1/380 17/18722 0.29442981410824 0.448690270870239 SPI1 1 GO:0061298 retina vasculature development in camera-type eye 1/380 17/18722 0.29442981410824 0.448690270870239 HIF1A 1 GO:0061450 trophoblast cell migration 1/380 17/18722 0.29442981410824 0.448690270870239 ARHGDIB 1 GO:0061952 midbody abscission 1/380 17/18722 0.29442981410824 0.448690270870239 VPS4B 1 GO:0070293 renal absorption 1/380 17/18722 0.29442981410824 0.448690270870239 HBB 1 GO:0072673 lamellipodium morphogenesis 1/380 17/18722 0.29442981410824 0.448690270870239 CD44 1 GO:0090036 regulation of protein kinase C signaling 1/380 17/18722 0.29442981410824 0.448690270870239 MYADM 1 GO:0090399 replicative senescence 1/380 17/18722 0.29442981410824 0.448690270870239 MME 1 GO:0097067 cellular response to thyroid hormone stimulus 1/380 17/18722 0.29442981410824 0.448690270870239 CTSS 1 GO:0140354 lipid import into cell 1/380 17/18722 0.29442981410824 0.448690270870239 ACSL1 1 GO:1901550 regulation of endothelial cell development 1/380 17/18722 0.29442981410824 0.448690270870239 IL1B 1 GO:1901569 fatty acid derivative catabolic process 1/380 17/18722 0.29442981410824 0.448690270870239 CYP4F3 1 GO:1903140 regulation of establishment of endothelial barrier 1/380 17/18722 0.29442981410824 0.448690270870239 IL1B 1 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 1/380 17/18722 0.29442981410824 0.448690270870239 PPP3CA 1 GO:1903358 regulation of Golgi organization 1/380 17/18722 0.29442981410824 0.448690270870239 MAPK1 1 GO:1903540 establishment of protein localization to postsynaptic membrane 1/380 17/18722 0.29442981410824 0.448690270870239 STX3 1 GO:1904355 positive regulation of telomere capping 1/380 17/18722 0.29442981410824 0.448690270870239 MAPK1 1 GO:2000811 negative regulation of anoikis 1/380 17/18722 0.29442981410824 0.448690270870239 MCL1 1 GO:0015931 nucleobase-containing compound transport 6/380 222/18722 0.29667313833146 0.451946309652422 MX2/ZFP36/ZFP36L1/TGFBR2/NUP214/ZC3H11A 6 GO:0010389 regulation of G2/M transition of mitotic cell cycle 3/380 94/18722 0.298073075487513 0.453915668712555 NABP1/VPS4B/NBN 3 GO:0043401 steroid hormone mediated signaling pathway 4/380 136/18722 0.298493446291554 0.454066000375263 TAF7/DDX5/PAK1/NCOA4 4 GO:0043624 cellular protein complex disassembly 4/380 136/18722 0.298493446291554 0.454066000375263 PLEK/CAPZA1/VPS4B/TMOD3 4 GO:0045727 positive regulation of translation 4/380 136/18722 0.298493446291554 0.454066000375263 VIM/DDX3X/PPP1R15A/MAPK1 4 GO:0007626 locomotory behavior 5/380 179/18722 0.298818302068543 0.454396951260423 LRRK2/ARRB2/PTEN/AGTPBP1/EGR1 5 GO:0001706 endoderm formation 2/380 54/18722 0.299910355751936 0.45491416784006 DUSP1/ITGB2 2 GO:0014888 striated muscle adaptation 2/380 54/18722 0.299910355751936 0.45491416784006 CFLAR/PPP3CA 2 GO:0043647 inositol phosphate metabolic process 2/380 54/18722 0.299910355751936 0.45491416784006 PLEK/PTEN 2 GO:0060350 endochondral bone morphogenesis 2/380 54/18722 0.299910355751936 0.45491416784006 ALPL/TGFBR2 2 GO:0072698 protein localization to microtubule cytoskeleton 2/380 54/18722 0.299910355751936 0.45491416784006 SNX10/CEP350 2 GO:2000179 positive regulation of neural precursor cell proliferation 2/380 54/18722 0.299910355751936 0.45491416784006 LYN/HIF1A 2 GO:2000300 regulation of synaptic vesicle exocytosis 2/380 54/18722 0.299910355751936 0.45491416784006 LRRK2/PRKCB 2 GO:0010631 epithelial cell migration 9/380 357/18722 0.301433043353581 0.457060128393274 PTGS2/TMSB4X/PTEN/GLUL/TGFBR2/HIF1A/MYH9/NFE2L2/DOCK5 9 GO:0071897 DNA biosynthetic process 5/380 180/18722 0.302772174308396 0.457992480604767 DUSP1/CDKN2D/ARRB2/USP10/MAPK1 5 GO:0000086 G2/M transition of mitotic cell cycle 4/380 137/18722 0.303059290489898 0.457992480604767 NABP1/BACH1/VPS4B/NBN 4 GO:0006986 response to unfolded protein 4/380 137/18722 0.303059290489898 0.457992480604767 CREBRF/HSPA1A/PPP1R15A/NFE2L2 4 GO:0010977 negative regulation of neuron projection development 4/380 137/18722 0.303059290489898 0.457992480604767 LRRK2/B2M/VIM/PTEN 4 GO:0050684 regulation of mRNA processing 4/380 137/18722 0.303059290489898 0.457992480604767 CELF2/ZFP36L1/DDX5/SF1 4 GO:0050714 positive regulation of protein secretion 4/380 137/18722 0.303059290489898 0.457992480604767 HCAR2/GLUL/NADK/HIF1A 4 GO:0060078 regulation of postsynaptic membrane potential 4/380 137/18722 0.303059290489898 0.457992480604767 LRRK2/ARRB2/PTEN/PPP3CA 4 GO:0007044 cell-substrate junction assembly 3/380 95/18722 0.303626970303853 0.457992480604767 PTEN/IQGAP1/ACTN1 3 GO:0032479 regulation of type I interferon production 3/380 95/18722 0.303626970303853 0.457992480604767 PYCARD/IRF1/DDX3X 3 GO:0032606 type I interferon production 3/380 95/18722 0.303626970303853 0.457992480604767 PYCARD/IRF1/DDX3X 3 GO:0045666 positive regulation of neuron differentiation 3/380 95/18722 0.303626970303853 0.457992480604767 BCL6/PTEN/NCOA1 3 GO:0032984 protein-containing complex disassembly 6/380 224/18722 0.303730510634585 0.457992480604767 PLEK/IRAK3/VMP1/CAPZA1/VPS4B/TMOD3 6 GO:0030323 respiratory tube development 5/380 181/18722 0.306734125387719 0.457992480604767 KLF2/TGFBR2/YWHAZ/MME/MAPK1 5 GO:0008037 cell recognition 6/380 225/18722 0.307270769391693 0.457992480604767 PECAM1/CXCR4/CLEC7A/FCN1/MSN/YWHAZ 6 GO:0048016 inositol phosphate-mediated signaling 2/380 55/18722 0.307425545933983 0.457992480604767 CLEC7A/PPP3CA 2 GO:0051898 negative regulation of protein kinase B signaling 2/380 55/18722 0.307425545933983 0.457992480604767 ARRB2/PTEN 2 GO:0061098 positive regulation of protein tyrosine kinase activity 2/380 55/18722 0.307425545933983 0.457992480604767 NCF1/PAK2 2 GO:0002501 peptide antigen assembly with MHC protein complex 1/380 18/18722 0.308763771373081 0.457992480604767 B2M 1 GO:0003417 growth plate cartilage development 1/380 18/18722 0.308763771373081 0.457992480604767 TGFBR2 1 GO:0006625 protein targeting to peroxisome 1/380 18/18722 0.308763771373081 0.457992480604767 RAB8B 1 GO:0006991 response to sterol depletion 1/380 18/18722 0.308763771373081 0.457992480604767 LYN 1 GO:0007549 dosage compensation 1/380 18/18722 0.308763771373081 0.457992480604767 SMCHD1 1 GO:0009125 nucleoside monophosphate catabolic process 1/380 18/18722 0.308763771373081 0.457992480604767 TYMP 1 GO:0009404 toxin metabolic process 1/380 18/18722 0.308763771373081 0.457992480604767 NFE2L2 1 GO:0015732 prostaglandin transport 1/380 18/18722 0.308763771373081 0.457992480604767 IL1B 1 GO:0019184 nonribosomal peptide biosynthetic process 1/380 18/18722 0.308763771373081 0.457992480604767 NFE2L2 1 GO:0021534 cell proliferation in hindbrain 1/380 18/18722 0.308763771373081 0.457992480604767 C5AR1 1 GO:0032305 positive regulation of icosanoid secretion 1/380 18/18722 0.308763771373081 0.457992480604767 IL1B 1 GO:0033189 response to vitamin A 1/380 18/18722 0.308763771373081 0.457992480604767 CAT 1 GO:0034162 toll-like receptor 9 signaling pathway 1/380 18/18722 0.308763771373081 0.457992480604767 PIK3AP1 1 GO:0035743 CD4-positive, alpha-beta T cell cytokine production 1/380 18/18722 0.308763771373081 0.457992480604767 IL1B 1 GO:0045116 protein neddylation 1/380 18/18722 0.308763771373081 0.457992480604767 HIF1A 1 GO:0045623 negative regulation of T-helper cell differentiation 1/380 18/18722 0.308763771373081 0.457992480604767 BCL6 1 GO:0046838 phosphorylated carbohydrate dephosphorylation 1/380 18/18722 0.308763771373081 0.457992480604767 PTEN 1 GO:0048268 clathrin coat assembly 1/380 18/18722 0.308763771373081 0.457992480604767 PICALM 1 GO:0048535 lymph node development 1/380 18/18722 0.308763771373081 0.457992480604767 LTB 1 GO:0051782 negative regulation of cell division 1/380 18/18722 0.308763771373081 0.457992480604767 TXNIP 1 GO:0051895 negative regulation of focal adhesion assembly 1/380 18/18722 0.308763771373081 0.457992480604767 PTEN 1 GO:0060192 negative regulation of lipase activity 1/380 18/18722 0.308763771373081 0.457992480604767 RGS2 1 GO:0060546 negative regulation of necroptotic process 1/380 18/18722 0.308763771373081 0.457992480604767 PELI1 1 GO:0060749 mammary gland alveolus development 1/380 18/18722 0.308763771373081 0.457992480604767 HIF1A 1 GO:0061377 mammary gland lobule development 1/380 18/18722 0.308763771373081 0.457992480604767 HIF1A 1 GO:0061484 hematopoietic stem cell homeostasis 1/380 18/18722 0.308763771373081 0.457992480604767 ADAR 1 GO:0071318 cellular response to ATP 1/380 18/18722 0.308763771373081 0.457992480604767 PTGS2 1 GO:0071360 cellular response to exogenous dsRNA 1/380 18/18722 0.308763771373081 0.457992480604767 RALB 1 GO:0071786 endoplasmic reticulum tubular network organization 1/380 18/18722 0.308763771373081 0.457992480604767 RTN3 1 GO:0072662 protein localization to peroxisome 1/380 18/18722 0.308763771373081 0.457992480604767 RAB8B 1 GO:0072663 establishment of protein localization to peroxisome 1/380 18/18722 0.308763771373081 0.457992480604767 RAB8B 1 GO:0080182 histone H3-K4 trimethylation 1/380 18/18722 0.308763771373081 0.457992480604767 TET2 1 GO:0090493 catecholamine uptake 1/380 18/18722 0.308763771373081 0.457992480604767 ACTB 1 GO:0097107 postsynaptic density assembly 1/380 18/18722 0.308763771373081 0.457992480604767 PTEN 1 GO:0098877 neurotransmitter receptor transport to plasma membrane 1/380 18/18722 0.308763771373081 0.457992480604767 STX3 1 GO:0110154 RNA decapping 1/380 18/18722 0.308763771373081 0.457992480604767 ZFP36 1 GO:0150118 negative regulation of cell-substrate junction organization 1/380 18/18722 0.308763771373081 0.457992480604767 PTEN 1 GO:1900006 positive regulation of dendrite development 1/380 18/18722 0.308763771373081 0.457992480604767 IQGAP1 1 GO:1900225 regulation of NLRP3 inflammasome complex assembly 1/380 18/18722 0.308763771373081 0.457992480604767 DDX3X 1 GO:1900242 regulation of synaptic vesicle endocytosis 1/380 18/18722 0.308763771373081 0.457992480604767 LRRK2 1 GO:1900424 regulation of defense response to bacterium 1/380 18/18722 0.308763771373081 0.457992480604767 CYBA 1 GO:1902001 fatty acid transmembrane transport 1/380 18/18722 0.308763771373081 0.457992480604767 ACSL1 1 GO:1902170 cellular response to reactive nitrogen species 1/380 18/18722 0.308763771373081 0.457992480604767 CFLAR 1 GO:1903209 positive regulation of oxidative stress-induced cell death 1/380 18/18722 0.308763771373081 0.457992480604767 MCL1 1 GO:2001135 regulation of endocytic recycling 1/380 18/18722 0.308763771373081 0.457992480604767 SORL1 1 GO:0003073 regulation of systemic arterial blood pressure 3/380 96/18722 0.309185478642037 0.457992480604767 SOD2/CYBA/MME 3 GO:0030510 regulation of BMP signaling pathway 3/380 96/18722 0.309185478642037 0.457992480604767 SORL1/UBE2D1/UBE2D3 3 GO:0034620 cellular response to unfolded protein 3/380 96/18722 0.309185478642037 0.457992480604767 HSPA1A/PPP1R15A/NFE2L2 3 GO:0051304 chromosome separation 3/380 96/18722 0.309185478642037 0.457992480604767 DUSP1/PLSCR1/CUL3 3 GO:0090132 epithelium migration 9/380 360/18722 0.309785646829325 0.458721053958808 PTGS2/TMSB4X/PTEN/GLUL/TGFBR2/HIF1A/MYH9/NFE2L2/DOCK5 9 GO:0060401 cytosolic calcium ion transport 5/380 182/18722 0.310703668957996 0.459919621823528 PTPRC/LYN/CORO1A/CYBA/PTPN6 5 GO:0098657 import into cell 6/380 227/18722 0.314372694287024 0.464868242085819 RGS2/ACSL1/STEAP4/KCNJ15/SLC2A3/ACTB 6 GO:0043470 regulation of carbohydrate catabolic process 2/380 56/18722 0.314924908274903 0.464868242085819 STAT3/HIF1A 2 GO:0046622 positive regulation of organ growth 2/380 56/18722 0.314924908274903 0.464868242085819 BASP1/MAPK1 2 GO:0048008 platelet-derived growth factor receptor signaling pathway 2/380 56/18722 0.314924908274903 0.464868242085819 TXNIP/PTEN 2 GO:0048255 mRNA stabilization 2/380 56/18722 0.314924908274903 0.464868242085819 ZFP36/SLC11A1 2 GO:0051058 negative regulation of small GTPase mediated signal transduction 2/380 56/18722 0.314924908274903 0.464868242085819 BCL6/CUL3 2 GO:0051784 negative regulation of nuclear division 2/380 56/18722 0.314924908274903 0.464868242085819 DUSP1/PRKAR1A 2 GO:1904645 response to amyloid-beta 2/380 56/18722 0.314924908274903 0.464868242085819 NAMPT/FPR2 2 GO:0071695 anatomical structure maturation 6/380 229/18722 0.321500857610623 0.470274794157481 LRRK2/KLF2/SNX10/CLEC7A/PTBP3/HIF1A 6 GO:0002011 morphogenesis of an epithelial sheet 2/380 57/18722 0.322405993919666 0.470274794157481 PTEN/CD44 2 GO:0006754 ATP biosynthetic process 2/380 57/18722 0.322405993919666 0.470274794157481 TMSB4X/STAT3 2 GO:0061005 cell differentiation involved in kidney development 2/380 57/18722 0.322405993919666 0.470274794157481 BASP1/IQGAP1 2 GO:0001696 gastric acid secretion 1/380 19/18722 0.322807279011995 0.470274794157481 SNX10 1 GO:0002281 macrophage activation involved in immune response 1/380 19/18722 0.322807279011995 0.470274794157481 TYROBP 1 GO:0002396 MHC protein complex assembly 1/380 19/18722 0.322807279011995 0.470274794157481 B2M 1 GO:0003085 negative regulation of systemic arterial blood pressure 1/380 19/18722 0.322807279011995 0.470274794157481 SOD2 1 GO:0006309 apoptotic DNA fragmentation 1/380 19/18722 0.322807279011995 0.470274794157481 DICER1 1 GO:0006491 N-glycan processing 1/380 19/18722 0.322807279011995 0.470274794157481 ST8SIA4 1 GO:0007530 sex determination 1/380 19/18722 0.322807279011995 0.470274794157481 SF1 1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1/380 19/18722 0.322807279011995 0.470274794157481 TYMP 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/380 19/18722 0.322807279011995 0.470274794157481 PTEN 1 GO:0015802 basic amino acid transport 1/380 19/18722 0.322807279011995 0.470274794157481 SLC11A1 1 GO:0030011 maintenance of cell polarity 1/380 19/18722 0.322807279011995 0.470274794157481 ARPC5 1 GO:0030050 vesicle transport along actin filament 1/380 19/18722 0.322807279011995 0.470274794157481 MYO1F 1 GO:0032011 ARF protein signal transduction 1/380 19/18722 0.322807279011995 0.470274794157481 CYTH4 1 GO:0032012 regulation of ARF protein signal transduction 1/380 19/18722 0.322807279011995 0.470274794157481 CYTH4 1 GO:0032616 interleukin-13 production 1/380 19/18722 0.322807279011995 0.470274794157481 HLA-E 1 GO:0032656 regulation of interleukin-13 production 1/380 19/18722 0.322807279011995 0.470274794157481 HLA-E 1 GO:0033194 response to hydroperoxide 1/380 19/18722 0.322807279011995 0.470274794157481 AIF1 1 GO:0035313 wound healing, spreading of epidermal cells 1/380 19/18722 0.322807279011995 0.470274794157481 PTEN 1 GO:0043031 negative regulation of macrophage activation 1/380 19/18722 0.322807279011995 0.470274794157481 PTPRC 1 GO:0044546 NLRP3 inflammasome complex assembly 1/380 19/18722 0.322807279011995 0.470274794157481 DDX3X 1 GO:0045019 negative regulation of nitric oxide biosynthetic process 1/380 19/18722 0.322807279011995 0.470274794157481 TSPO 1 GO:0045603 positive regulation of endothelial cell differentiation 1/380 19/18722 0.322807279011995 0.470274794157481 BTG1 1 GO:0045821 positive regulation of glycolytic process 1/380 19/18722 0.322807279011995 0.470274794157481 HIF1A 1 GO:0046716 muscle cell cellular homeostasis 1/380 19/18722 0.322807279011995 0.470274794157481 HIF1A 1 GO:0051546 keratinocyte migration 1/380 19/18722 0.322807279011995 0.470274794157481 PTEN 1 GO:0062099 negative regulation of programmed necrotic cell death 1/380 19/18722 0.322807279011995 0.470274794157481 PELI1 1 GO:0070989 oxidative demethylation 1/380 19/18722 0.322807279011995 0.470274794157481 TET2 1 GO:0071545 inositol phosphate catabolic process 1/380 19/18722 0.322807279011995 0.470274794157481 PTEN 1 GO:0072074 kidney mesenchyme development 1/380 19/18722 0.322807279011995 0.470274794157481 BASP1 1 GO:1901881 positive regulation of protein depolymerization 1/380 19/18722 0.322807279011995 0.470274794157481 PLEK 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/380 19/18722 0.322807279011995 0.470274794157481 HIF1A 1 GO:1904406 negative regulation of nitric oxide metabolic process 1/380 19/18722 0.322807279011995 0.470274794157481 TSPO 1 GO:2000042 negative regulation of double-strand break repair via homologous recombination 1/380 19/18722 0.322807279011995 0.470274794157481 SMCHD1 1 GO:2000319 regulation of T-helper 17 cell differentiation 1/380 19/18722 0.322807279011995 0.470274794157481 NFKBIZ 1 GO:0090130 tissue migration 9/380 365/18722 0.323819555527604 0.471587282551377 PTGS2/TMSB4X/PTEN/GLUL/TGFBR2/HIF1A/MYH9/NFE2L2/DOCK5 9 GO:0051153 regulation of striated muscle cell differentiation 3/380 99/18722 0.32587632055127 0.474419462885743 RGS2/ARRB2/PAK1 3 GO:0031345 negative regulation of cell projection organization 5/380 186/18722 0.326648137964395 0.475379678446465 LRRK2/B2M/VIM/PTEN/PPP3CA 5 GO:0032481 positive regulation of type I interferon production 2/380 58/18722 0.329866459412364 0.47940441167171 IRF1/DDX3X 2 GO:0044380 protein localization to cytoskeleton 2/380 58/18722 0.329866459412364 0.47940441167171 SNX10/CEP350 2 GO:0045604 regulation of epidermal cell differentiation 2/380 58/18722 0.329866459412364 0.47940441167171 ZFP36/ZFP36L1 2 GO:1902808 positive regulation of cell cycle G1/S phase transition 2/380 58/18722 0.329866459412364 0.47940441167171 AIF1/DDX3X 2 GO:0019218 regulation of steroid metabolic process 3/380 100/18722 0.331441037422284 0.481197392349459 TSPO/EGR1/SF1 3 GO:0051588 regulation of neurotransmitter transport 3/380 100/18722 0.331441037422284 0.481197392349459 LRRK2/PRKCB/MCTP2 3 GO:0061640 cytoskeleton-dependent cytokinesis 3/380 100/18722 0.331441037422284 0.481197392349459 ACTR2/ACTR3/VPS4B 3 GO:0046034 ATP metabolic process 7/380 277/18722 0.332167986774805 0.482087533924366 TMSB4X/TSPO/STAT3/BID/NADK/HIF1A/HSPA1A 7 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 6/380 233/18722 0.335824926016613 0.483412084160336 RGS2/FPR1/FPR2/ADGRE2/ADGRE5/GPR65 6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle 1/380 20/18722 0.33656620720402 0.483412084160336 BACH1 1 GO:0001832 blastocyst growth 1/380 20/18722 0.33656620720402 0.483412084160336 NBN 1 GO:0006607 NLS-bearing protein import into nucleus 1/380 20/18722 0.33656620720402 0.483412084160336 KPNA4 1 GO:0006896 Golgi to vacuole transport 1/380 20/18722 0.33656620720402 0.483412084160336 LAPTM5 1 GO:0007194 negative regulation of adenylate cyclase activity 1/380 20/18722 0.33656620720402 0.483412084160336 P2RY13 1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1/380 20/18722 0.33656620720402 0.483412084160336 TYMP 1 GO:0015919 peroxisomal membrane transport 1/380 20/18722 0.33656620720402 0.483412084160336 RAB8B 1 GO:0017121 plasma membrane phospholipid scrambling 1/380 20/18722 0.33656620720402 0.483412084160336 PLSCR1 1 GO:0031645 negative regulation of nervous system process 1/380 20/18722 0.33656620720402 0.483412084160336 PTEN 1 GO:0032495 response to muramyl dipeptide 1/380 20/18722 0.33656620720402 0.483412084160336 VIM 1 GO:0033005 positive regulation of mast cell activation 1/380 20/18722 0.33656620720402 0.483412084160336 FGR 1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 1/380 20/18722 0.33656620720402 0.483412084160336 ITM2B 1 GO:0043984 histone H4-K16 acetylation 1/380 20/18722 0.33656620720402 0.483412084160336 MSL1 1 GO:0046485 ether lipid metabolic process 1/380 20/18722 0.33656620720402 0.483412084160336 LPCAT2 1 GO:0060231 mesenchymal to epithelial transition 1/380 20/18722 0.33656620720402 0.483412084160336 BASP1 1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway 1/380 20/18722 0.33656620720402 0.483412084160336 ADAR 1 GO:0061003 positive regulation of dendritic spine morphogenesis 1/380 20/18722 0.33656620720402 0.483412084160336 ACTR2 1 GO:0071243 cellular response to arsenic-containing substance 1/380 20/18722 0.33656620720402 0.483412084160336 DDX3X 1 GO:0072567 chemokine (C-X-C motif) ligand 2 production 1/380 20/18722 0.33656620720402 0.483412084160336 MBP 1 GO:0090201 negative regulation of release of cytochrome c from mitochondria 1/380 20/18722 0.33656620720402 0.483412084160336 ARRB2 1 GO:0097320 plasma membrane tubulation 1/380 20/18722 0.33656620720402 0.483412084160336 SH3GLB1 1 GO:0097503 sialylation 1/380 20/18722 0.33656620720402 0.483412084160336 ST8SIA4 1 GO:0140632 inflammasome complex assembly 1/380 20/18722 0.33656620720402 0.483412084160336 DDX3X 1 GO:1902004 positive regulation of amyloid-beta formation 1/380 20/18722 0.33656620720402 0.483412084160336 PICALM 1 GO:1904292 regulation of ERAD pathway 1/380 20/18722 0.33656620720402 0.483412084160336 NFE2L2 1 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 1/380 20/18722 0.33656620720402 0.483412084160336 MBP 1 GO:2000479 regulation of cAMP-dependent protein kinase activity 1/380 20/18722 0.33656620720402 0.483412084160336 PRKAR1A 1 GO:2000678 negative regulation of transcription regulatory region DNA binding 1/380 20/18722 0.33656620720402 0.483412084160336 TMSB4X 1 GO:0006476 protein deacetylation 3/380 101/18722 0.337004363842847 0.483412084160336 LRRK2/BCL6/KDM5A 3 GO:0006576 cellular biogenic amine metabolic process 3/380 101/18722 0.337004363842847 0.483412084160336 ITGB2/SAT1/OAZ1 3 GO:0048024 regulation of mRNA splicing, via spliceosome 3/380 101/18722 0.337004363842847 0.483412084160336 CELF2/DDX5/SF1 3 GO:0006406 mRNA export from nucleus 2/380 59/18722 0.337304063445996 0.483412084160336 NUP214/ZC3H11A 2 GO:0006767 water-soluble vitamin metabolic process 2/380 59/18722 0.337304063445996 0.483412084160336 VNN2/SLC2A3 2 GO:0032768 regulation of monooxygenase activity 2/380 59/18722 0.337304063445996 0.483412084160336 IL1B/HIF1A 2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2/380 59/18722 0.337304063445996 0.483412084160336 PTPRC/PTPN6 2 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 2/380 59/18722 0.337304063445996 0.483412084160336 NUP214/ZC3H11A 2 GO:0043542 endothelial cell migration 7/380 279/18722 0.338725583591394 0.485285130754247 PTGS2/TMSB4X/PTEN/GLUL/HIF1A/MYH9/NFE2L2 7 GO:0048588 developmental cell growth 6/380 234/18722 0.339418073933576 0.486112797804766 RGS2/IQGAP1/CXCR4/TGFBR2/NIN/PAK1 6 GO:0060562 epithelial tube morphogenesis 8/380 325/18722 0.340230052946434 0.487110978440889 CXCR2/ITGAX/CXCR4/STK4/VASP/TGFBR2/HIF1A/PAK1 8 GO:0001841 neural tube formation 3/380 102/18722 0.342565170366214 0.489950223436037 STK4/VASP/HIF1A 3 GO:0062014 negative regulation of small molecule metabolic process 3/380 102/18722 0.342565170366214 0.489950223436037 CDA/PLEK/STAT3 3 GO:1902749 regulation of cell cycle G2/M phase transition 3/380 102/18722 0.342565170366214 0.489950223436037 NABP1/VPS4B/NBN 3 GO:0046390 ribose phosphate biosynthetic process 5/380 190/18722 0.342675929590919 0.489950223436037 ACSL1/TMSB4X/PYGL/ELOVL5/STAT3 5 GO:0007043 cell-cell junction assembly 4/380 146/18722 0.344415343315537 0.491209646961729 ACTB/IL1B/PECAM1/PAK2 4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 2/380 60/18722 0.344716663700179 0.491209646961729 CELF2/DDX5 2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 2/380 60/18722 0.344716663700179 0.491209646961729 NABP1/NBN 2 GO:0019731 antibacterial humoral response 2/380 60/18722 0.344716663700179 0.491209646961729 HLA-E/HLA-A 2 GO:0030071 regulation of mitotic metaphase/anaphase transition 2/380 60/18722 0.344716663700179 0.491209646961729 DUSP1/CUL3 2 GO:0031102 neuron projection regeneration 2/380 60/18722 0.344716663700179 0.491209646961729 TSPO/PTEN 2 GO:0031638 zymogen activation 2/380 60/18722 0.344716663700179 0.491209646961729 PYCARD/IFI16 2 GO:0033866 nucleoside bisphosphate biosynthetic process 2/380 60/18722 0.344716663700179 0.491209646961729 ACSL1/ELOVL5 2 GO:0034030 ribonucleoside bisphosphate biosynthetic process 2/380 60/18722 0.344716663700179 0.491209646961729 ACSL1/ELOVL5 2 GO:0034033 purine nucleoside bisphosphate biosynthetic process 2/380 60/18722 0.344716663700179 0.491209646961729 ACSL1/ELOVL5 2 GO:0098813 nuclear chromosome segregation 7/380 281/18722 0.345300361656268 0.491875893580321 DUSP1/ACTR2/ACTR3/UBE2B/STAG2/CUL3/VPS4B 7 GO:0007517 muscle organ development 8/380 327/18722 0.346322044059627 0.492016632430826 BASP1/FOS/CFLAR/BTG2/EGR1/DDX5/PPP3CA/MYL6 8 GO:0034329 cell junction assembly 10/380 420/18722 0.348850643841621 0.492016632430826 ACTB/IL1B/PECAM1/PTEN/SDCBP/IQGAP1/VMP1/CAPZA1/ACTN1/PAK2 10 GO:0001889 liver development 4/380 147/18722 0.349026825617422 0.492016632430826 CEBPB/CFLAR/IGF2R/CUL3 4 GO:0000002 mitochondrial genome maintenance 1/380 21/18722 0.350046307795532 0.492016632430826 TYMP 1 GO:0002689 negative regulation of leukocyte chemotaxis 1/380 21/18722 0.350046307795532 0.492016632430826 DUSP1 1 GO:0003177 pulmonary valve development 1/380 21/18722 0.350046307795532 0.492016632430826 TNFRSF1B 1 GO:0006244 pyrimidine nucleotide catabolic process 1/380 21/18722 0.350046307795532 0.492016632430826 TYMP 1 GO:0007350 blastoderm segmentation 1/380 21/18722 0.350046307795532 0.492016632430826 BASP1 1 GO:0008090 retrograde axonal transport 1/380 21/18722 0.350046307795532 0.492016632430826 AGTPBP1 1 GO:0019985 translesion synthesis 1/380 21/18722 0.350046307795532 0.492016632430826 USP10 1 GO:0021533 cell differentiation in hindbrain 1/380 21/18722 0.350046307795532 0.492016632430826 AGTPBP1 1 GO:0022010 central nervous system myelination 1/380 21/18722 0.350046307795532 0.492016632430826 PTEN 1 GO:0031145 anaphase-promoting complex-dependent catabolic process 1/380 21/18722 0.350046307795532 0.492016632430826 CUL3 1 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane 1/380 21/18722 0.350046307795532 0.492016632430826 STX3 1 GO:0032288 myelin assembly 1/380 21/18722 0.350046307795532 0.492016632430826 DICER1 1 GO:0032291 axon ensheathment in central nervous system 1/380 21/18722 0.350046307795532 0.492016632430826 PTEN 1 GO:0032303 regulation of icosanoid secretion 1/380 21/18722 0.350046307795532 0.492016632430826 IL1B 1 GO:0032482 Rab protein signal transduction 1/380 21/18722 0.350046307795532 0.492016632430826 DENND3 1 GO:0033630 positive regulation of cell adhesion mediated by integrin 1/380 21/18722 0.350046307795532 0.492016632430826 PTPN6 1 GO:0038083 peptidyl-tyrosine autophosphorylation 1/380 21/18722 0.350046307795532 0.492016632430826 IQGAP1 1 GO:0039702 viral budding via host ESCRT complex 1/380 21/18722 0.350046307795532 0.492016632430826 VPS4B 1 GO:0044766 multi-organism transport 1/380 21/18722 0.350046307795532 0.492016632430826 RAB7A 1 GO:0045655 regulation of monocyte differentiation 1/380 21/18722 0.350046307795532 0.492016632430826 ZFP36L1 1 GO:0046599 regulation of centriole replication 1/380 21/18722 0.350046307795532 0.492016632430826 VPS4B 1 GO:0048199 vesicle targeting, to, from or within Golgi 1/380 21/18722 0.350046307795532 0.492016632430826 CUL3 1 GO:0050849 negative regulation of calcium-mediated signaling 1/380 21/18722 0.350046307795532 0.492016632430826 PLEK 1 GO:0051152 positive regulation of smooth muscle cell differentiation 1/380 21/18722 0.350046307795532 0.492016632430826 SOD2 1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1/380 21/18722 0.350046307795532 0.492016632430826 LAPTM5 1 GO:0072170 metanephric tubule development 1/380 21/18722 0.350046307795532 0.492016632430826 CXCR2 1 GO:0098698 postsynaptic specialization assembly 1/380 21/18722 0.350046307795532 0.492016632430826 PTEN 1 GO:0099500 vesicle fusion to plasma membrane 1/380 21/18722 0.350046307795532 0.492016632430826 STX3 1 GO:0099515 actin filament-based transport 1/380 21/18722 0.350046307795532 0.492016632430826 MYO1F 1 GO:1900118 negative regulation of execution phase of apoptosis 1/380 21/18722 0.350046307795532 0.492016632430826 PAK2 1 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/380 21/18722 0.350046307795532 0.492016632430826 HSPA1A 1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/380 21/18722 0.350046307795532 0.492016632430826 CD44 1 GO:1902579 multi-organism localization 1/380 21/18722 0.350046307795532 0.492016632430826 RAB7A 1 GO:1905209 positive regulation of cardiocyte differentiation 1/380 21/18722 0.350046307795532 0.492016632430826 ARRB2 1 GO:2000178 negative regulation of neural precursor cell proliferation 1/380 21/18722 0.350046307795532 0.492016632430826 BTG2 1 GO:2000291 regulation of myoblast proliferation 1/380 21/18722 0.350046307795532 0.492016632430826 MALAT1 1 GO:2001014 regulation of skeletal muscle cell differentiation 1/380 21/18722 0.350046307795532 0.492016632430826 DDX5 1 GO:0060998 regulation of dendritic spine development 2/380 61/18722 0.352102213764617 0.49474216167656 PTEN/ACTR2 2 GO:0035148 tube formation 4/380 148/18722 0.353639088912832 0.496407537801076 STK4/VASP/YWHAZ/HIF1A 4 GO:0044839 cell cycle G2/M phase transition 4/380 148/18722 0.353639088912832 0.496407537801076 NABP1/BACH1/VPS4B/NBN 4 GO:0070507 regulation of microtubule cytoskeleton organization 4/380 148/18722 0.353639088912832 0.496407537801076 NIN/HSPA1A/VPS4B/PAK1 4 GO:1905039 carboxylic acid transmembrane transport 4/380 149/18722 0.358251478936181 0.50271537882529 RGS2/AQP9/ACSL1/SLC16A3 4 GO:0016079 synaptic vesicle exocytosis 3/380 105/18722 0.359221532356466 0.503741842891735 LRRK2/PRKCB/STX3 3 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 2/380 62/18722 0.359458760146121 0.503741842891735 DUSP1/CUL3 2 GO:1902750 negative regulation of cell cycle G2/M phase transition 2/380 62/18722 0.359458760146121 0.503741842891735 NABP1/NBN 2 GO:1903078 positive regulation of protein localization to plasma membrane 2/380 62/18722 0.359458760146121 0.503741842891735 STX3/RHOG 2 GO:0030705 cytoskeleton-dependent intracellular transport 5/380 195/18722 0.362782779167346 0.503890393919872 MYO1F/TUBA1A/AGTPBP1/HIF1A/FLOT2 5 GO:0061008 hepaticobiliary system development 4/380 150/18722 0.362863350170302 0.503890393919872 CEBPB/CFLAR/IGF2R/CUL3 4 GO:1903825 organic acid transmembrane transport 4/380 150/18722 0.362863350170302 0.503890393919872 RGS2/AQP9/ACSL1/SLC16A3 4 GO:0002029 desensitization of G protein-coupled receptor signaling pathway 1/380 22/18722 0.363253216679426 0.503890393919872 ARRB2 1 GO:0002053 positive regulation of mesenchymal cell proliferation 1/380 22/18722 0.363253216679426 0.503890393919872 TGFBR2 1 GO:0006662 glycerol ether metabolic process 1/380 22/18722 0.363253216679426 0.503890393919872 LPCAT2 1 GO:0006907 pinocytosis 1/380 22/18722 0.363253216679426 0.503890393919872 PYCARD 1 GO:0021854 hypothalamus development 1/380 22/18722 0.363253216679426 0.503890393919872 NCOA1 1 GO:0022401 negative adaptation of signaling pathway 1/380 22/18722 0.363253216679426 0.503890393919872 ARRB2 1 GO:0022616 DNA strand elongation 1/380 22/18722 0.363253216679426 0.503890393919872 NBN 1 GO:0032069 regulation of nuclease activity 1/380 22/18722 0.363253216679426 0.503890393919872 HSPA1A 1 GO:0032402 melanosome transport 1/380 22/18722 0.363253216679426 0.503890393919872 RAB27A 1 GO:0032693 negative regulation of interleukin-10 production 1/380 22/18722 0.363253216679426 0.503890393919872 TYROBP 1 GO:0032727 positive regulation of interferon-alpha production 1/380 22/18722 0.363253216679426 0.503890393919872 DDX3X 1 GO:0032891 negative regulation of organic acid transport 1/380 22/18722 0.363253216679426 0.503890393919872 RGS2 1 GO:0035089 establishment of apical/basal cell polarity 1/380 22/18722 0.363253216679426 0.503890393919872 MSN 1 GO:0035561 regulation of chromatin binding 1/380 22/18722 0.363253216679426 0.503890393919872 PPP3CA 1 GO:0035584 calcium-mediated signaling using intracellular calcium source 1/380 22/18722 0.363253216679426 0.503890393919872 PTPRC 1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 1/380 22/18722 0.363253216679426 0.503890393919872 BCL6 1 GO:0043574 peroxisomal transport 1/380 22/18722 0.363253216679426 0.503890393919872 RAB8B 1 GO:0045061 thymic T cell selection 1/380 22/18722 0.363253216679426 0.503890393919872 PTPRC 1 GO:0045624 positive regulation of T-helper cell differentiation 1/380 22/18722 0.363253216679426 0.503890393919872 NFKBIZ 1 GO:0045663 positive regulation of myoblast differentiation 1/380 22/18722 0.363253216679426 0.503890393919872 BTG1 1 GO:0051220 cytoplasmic sequestering of protein 1/380 22/18722 0.363253216679426 0.503890393919872 TMSB4X 1 GO:0051412 response to corticosterone 1/380 22/18722 0.363253216679426 0.503890393919872 FOS 1 GO:0055093 response to hyperoxia 1/380 22/18722 0.363253216679426 0.503890393919872 CAT 1 GO:0060563 neuroepithelial cell differentiation 1/380 22/18722 0.363253216679426 0.503890393919872 CEBPB 1 GO:0071359 cellular response to dsRNA 1/380 22/18722 0.363253216679426 0.503890393919872 RALB 1 GO:1900120 regulation of receptor binding 1/380 22/18722 0.363253216679426 0.503890393919872 B2M 1 GO:1900543 negative regulation of purine nucleotide metabolic process 1/380 22/18722 0.363253216679426 0.503890393919872 STAT3 1 GO:2000725 regulation of cardiac muscle cell differentiation 1/380 22/18722 0.363253216679426 0.503890393919872 ARRB2 1 GO:0001824 blastocyst development 3/380 106/18722 0.364761439470728 0.505155230921691 JUNB/CUL3/NBN 3 GO:0006766 vitamin metabolic process 3/380 106/18722 0.364761439470728 0.505155230921691 VNN2/CYP4F3/SLC2A3 3 GO:0035821 modulation of process of other organism 3/380 106/18722 0.364761439470728 0.505155230921691 S100A9/CLEC7A/IGF2R 3 GO:0090263 positive regulation of canonical Wnt signaling pathway 3/380 106/18722 0.364761439470728 0.505155230921691 LRRK2/UBE2B/DDX3X 3 GO:2000278 regulation of DNA biosynthetic process 3/380 106/18722 0.364761439470728 0.505155230921691 DUSP1/ARRB2/MAPK1 3 GO:0140014 mitotic nuclear division 7/380 287/18722 0.36510739736141 0.505469051266941 DUSP1/IL1B/STAG2/HSPA1A/CUL3/VPS4B/PHIP 7 GO:0001947 heart looping 2/380 63/18722 0.366784439357103 0.506996494402341 TGFBR2/HIF1A 2 GO:0022617 extracellular matrix disassembly 2/380 63/18722 0.366784439357103 0.506996494402341 LCP1/CTSS 2 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 2/380 63/18722 0.366784439357103 0.506996494402341 DUSP1/CUL3 2 GO:1902373 negative regulation of mRNA catabolic process 2/380 63/18722 0.366784439357103 0.506996494402341 ZFP36/SLC11A1 2 GO:0045664 regulation of neuron differentiation 5/380 196/18722 0.366809270094161 0.506996494402341 LRRK2/BCL6/B2M/PTEN/NCOA1 5 GO:0043535 regulation of blood vessel endothelial cell migration 4/380 151/18722 0.367474065938173 0.507253151645425 PTGS2/TMSB4X/HIF1A/NFE2L2 4 GO:0055067 monovalent inorganic cation homeostasis 4/380 151/18722 0.367474065938173 0.507253151645425 LRRK2/SLC11A1/MAPK1/RAB7A 4 GO:0071333 cellular response to glucose stimulus 4/380 151/18722 0.367474065938173 0.507253151645425 CYBA/NADK/HIF1A/PPP3CA 4 GO:1904064 positive regulation of cation transmembrane transport 4/380 151/18722 0.367474065938173 0.507253151645425 CTSS/TMSB4X/VMP1/IFNGR2 4 GO:0006275 regulation of DNA replication 3/380 107/18722 0.370293534887432 0.510645757163228 BCL6/S100A11/NBN 3 GO:0071868 cellular response to monoamine stimulus 3/380 107/18722 0.370293534887432 0.510645757163228 LRRK2/ARRB2/MAPK1 3 GO:0071870 cellular response to catecholamine stimulus 3/380 107/18722 0.370293534887432 0.510645757163228 LRRK2/ARRB2/MAPK1 3 GO:0021915 neural tube development 4/380 152/18722 0.372082998487344 0.511616908059112 STK4/ZFP36L1/VASP/HIF1A 4 GO:0050871 positive regulation of B cell activation 4/380 152/18722 0.372082998487344 0.511616908059112 PTPRC/BCL6/PELI1/TNFSF13B 4 GO:0017156 calcium-ion regulated exocytosis 2/380 64/18722 0.374077475083464 0.511616908059112 STXBP3/MYH9 2 GO:0046530 photoreceptor cell differentiation 2/380 64/18722 0.374077475083464 0.511616908059112 AGTPBP1/STAT3 2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 2/380 64/18722 0.374077475083464 0.511616908059112 NADK/HIF1A 2 GO:0098930 axonal transport 2/380 64/18722 0.374077475083464 0.511616908059112 AGTPBP1/HIF1A 2 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 2/380 64/18722 0.374077475083464 0.511616908059112 SDCBP/N4BP1 2 GO:0002052 positive regulation of neuroblast proliferation 1/380 23/18722 0.376192456126582 0.511616908059112 HIF1A 1 GO:0006541 glutamine metabolic process 1/380 23/18722 0.376192456126582 0.511616908059112 GLUL 1 GO:0006833 water transport 1/380 23/18722 0.376192456126582 0.511616908059112 AQP9 1 GO:0009162 deoxyribonucleoside monophosphate metabolic process 1/380 23/18722 0.376192456126582 0.511616908059112 TYMP 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/380 23/18722 0.376192456126582 0.511616908059112 CARD16 1 GO:0010888 negative regulation of lipid storage 1/380 23/18722 0.376192456126582 0.511616908059112 OSBPL8 1 GO:0016578 histone deubiquitination 1/380 23/18722 0.376192456126582 0.511616908059112 USP15 1 GO:0016973 poly(A)+ mRNA export from nucleus 1/380 23/18722 0.376192456126582 0.511616908059112 ZC3H11A 1 GO:0021544 subpallium development 1/380 23/18722 0.376192456126582 0.511616908059112 LRRK2 1 GO:0023058 adaptation of signaling pathway 1/380 23/18722 0.376192456126582 0.511616908059112 ARRB2 1 GO:0030194 positive regulation of blood coagulation 1/380 23/18722 0.376192456126582 0.511616908059112 NFE2L2 1 GO:0030325 adrenal gland development 1/380 23/18722 0.376192456126582 0.511616908059112 TSPO 1 GO:0031280 negative regulation of cyclase activity 1/380 23/18722 0.376192456126582 0.511616908059112 P2RY13 1 GO:0031338 regulation of vesicle fusion 1/380 23/18722 0.376192456126582 0.511616908059112 CORO1A 1 GO:0032401 establishment of melanosome localization 1/380 23/18722 0.376192456126582 0.511616908059112 RAB27A 1 GO:0032740 positive regulation of interleukin-17 production 1/380 23/18722 0.376192456126582 0.511616908059112 OSM 1 GO:0033081 regulation of T cell differentiation in thymus 1/380 23/18722 0.376192456126582 0.511616908059112 SOS2 1 GO:0034105 positive regulation of tissue remodeling 1/380 23/18722 0.376192456126582 0.511616908059112 PPP3CA 1 GO:0035640 exploration behavior 1/380 23/18722 0.376192456126582 0.511616908059112 LRRK2 1 GO:0035994 response to muscle stretch 1/380 23/18722 0.376192456126582 0.511616908059112 FOS 1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 1/380 23/18722 0.376192456126582 0.511616908059112 VPS4B 1 GO:0043931 ossification involved in bone maturation 1/380 23/18722 0.376192456126582 0.511616908059112 SNX10 1 GO:0051131 chaperone-mediated protein complex assembly 1/380 23/18722 0.376192456126582 0.511616908059112 HSPA1A 1 GO:0051446 positive regulation of meiotic cell cycle 1/380 23/18722 0.376192456126582 0.511616908059112 UBE2B 1 GO:0051904 pigment granule transport 1/380 23/18722 0.376192456126582 0.511616908059112 RAB27A 1 GO:0060487 lung epithelial cell differentiation 1/380 23/18722 0.376192456126582 0.511616908059112 KLF2 1 GO:0060547 negative regulation of necrotic cell death 1/380 23/18722 0.376192456126582 0.511616908059112 PELI1 1 GO:0060575 intestinal epithelial cell differentiation 1/380 23/18722 0.376192456126582 0.511616908059112 HIF1A 1 GO:0071218 cellular response to misfolded protein 1/380 23/18722 0.376192456126582 0.511616908059112 CUL3 1 GO:0071636 positive regulation of transforming growth factor beta production 1/380 23/18722 0.376192456126582 0.511616908059112 PTGS2 1 GO:0090335 regulation of brown fat cell differentiation 1/380 23/18722 0.376192456126582 0.511616908059112 PTGS2 1 GO:0099590 neurotransmitter receptor internalization 1/380 23/18722 0.376192456126582 0.511616908059112 NUMB 1 GO:1900048 positive regulation of hemostasis 1/380 23/18722 0.376192456126582 0.511616908059112 NFE2L2 1 GO:1900273 positive regulation of long-term synaptic potentiation 1/380 23/18722 0.376192456126582 0.511616908059112 MME 1 GO:1902410 mitotic cytokinetic process 1/380 23/18722 0.376192456126582 0.511616908059112 VPS4B 1 GO:1904666 regulation of ubiquitin protein ligase activity 1/380 23/18722 0.376192456126582 0.511616908059112 PTEN 1 GO:0071331 cellular response to hexose stimulus 4/380 153/18722 0.37668952906728 0.512128460866752 CYBA/NADK/HIF1A/PPP3CA 4 GO:0051168 nuclear export 4/380 154/18722 0.381293047999781 0.516621466073415 IL1B/XPO6/NUP214/ZC3H11A 4 GO:0071326 cellular response to monosaccharide stimulus 4/380 154/18722 0.381293047999781 0.516621466073415 CYBA/NADK/HIF1A/PPP3CA 4 GO:0072009 nephron epithelium development 3/380 109/18722 0.381330362686431 0.516621466073415 BASP1/PECAM1/IQGAP1 3 GO:0003170 heart valve development 2/380 65/18722 0.381336175429869 0.516621466073415 TNFRSF1B/TGFBR2 2 GO:0010965 regulation of mitotic sister chromatid separation 2/380 65/18722 0.381336175429869 0.516621466073415 DUSP1/CUL3 2 GO:0043489 RNA stabilization 2/380 65/18722 0.381336175429869 0.516621466073415 ZFP36/SLC11A1 2 GO:0044784 metaphase/anaphase transition of cell cycle 2/380 65/18722 0.381336175429869 0.516621466073415 DUSP1/CUL3 2 GO:0045453 bone resorption 2/380 65/18722 0.381336175429869 0.516621466073415 RAC2/SNX10 2 GO:0045682 regulation of epidermis development 2/380 65/18722 0.381336175429869 0.516621466073415 ZFP36/ZFP36L1 2 GO:0048645 animal organ formation 2/380 65/18722 0.381336175429869 0.516621466073415 TGFBR2/MAPK1 2 GO:0051310 metaphase plate congression 2/380 65/18722 0.381336175429869 0.516621466073415 CUL3/VPS4B 2 GO:0051147 regulation of muscle cell differentiation 4/380 155/18722 0.385892954742666 0.520171214780141 SOD2/RGS2/ARRB2/PAK1 4 GO:0009408 response to heat 3/380 110/18722 0.386833189144862 0.520171214780141 PTGS2/LYN/HSPA1A 3 GO:0019229 regulation of vasoconstriction 2/380 66/18722 0.388558930240461 0.520171214780141 PTGS2/DOCK5 2 GO:0050922 negative regulation of chemotaxis 2/380 66/18722 0.388558930240461 0.520171214780141 AIF1/DUSP1 2 GO:0051893 regulation of focal adhesion assembly 2/380 66/18722 0.388558930240461 0.520171214780141 PTEN/IQGAP1 2 GO:0090109 regulation of cell-substrate junction assembly 2/380 66/18722 0.388558930240461 0.520171214780141 PTEN/IQGAP1 2 GO:2000573 positive regulation of DNA biosynthetic process 2/380 66/18722 0.388558930240461 0.520171214780141 ARRB2/MAPK1 2 GO:0002021 response to dietary excess 1/380 24/18722 0.388869437070584 0.520171214780141 SORL1 1 GO:0003148 outflow tract septum morphogenesis 1/380 24/18722 0.388869437070584 0.520171214780141 TGFBR2 1 GO:0003181 atrioventricular valve morphogenesis 1/380 24/18722 0.388869437070584 0.520171214780141 TGFBR2 1 GO:0006817 phosphate ion transport 1/380 24/18722 0.388869437070584 0.520171214780141 CEBPB 1 GO:0007035 vacuolar acidification 1/380 24/18722 0.388869437070584 0.520171214780141 SLC11A1 1 GO:0009219 pyrimidine deoxyribonucleotide metabolic process 1/380 24/18722 0.388869437070584 0.520171214780141 TYMP 1 GO:0010155 regulation of proton transport 1/380 24/18722 0.388869437070584 0.520171214780141 TMSB4X 1 GO:0016486 peptide hormone processing 1/380 24/18722 0.388869437070584 0.520171214780141 MME 1 GO:0018230 peptidyl-L-cysteine S-palmitoylation 1/380 24/18722 0.388869437070584 0.520171214780141 ZDHHC18 1 GO:0018231 peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine 1/380 24/18722 0.388869437070584 0.520171214780141 ZDHHC18 1 GO:0021697 cerebellar cortex formation 1/380 24/18722 0.388869437070584 0.520171214780141 AGTPBP1 1 GO:0021801 cerebral cortex radial glia-guided migration 1/380 24/18722 0.388869437070584 0.520171214780141 MBOAT7 1 GO:0022030 telencephalon glial cell migration 1/380 24/18722 0.388869437070584 0.520171214780141 MBOAT7 1 GO:0030859 polarized epithelial cell differentiation 1/380 24/18722 0.388869437070584 0.520171214780141 MSN 1 GO:0030878 thyroid gland development 1/380 24/18722 0.388869437070584 0.520171214780141 MAPK1 1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1/380 24/18722 0.388869437070584 0.520171214780141 PHIP 1 GO:0050820 positive regulation of coagulation 1/380 24/18722 0.388869437070584 0.520171214780141 NFE2L2 1 GO:0051000 positive regulation of nitric-oxide synthase activity 1/380 24/18722 0.388869437070584 0.520171214780141 HIF1A 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/380 24/18722 0.388869437070584 0.520171214780141 TAF7 1 GO:0051156 glucose 6-phosphate metabolic process 1/380 24/18722 0.388869437070584 0.520171214780141 TALDO1 1 GO:0051905 establishment of pigment granule localization 1/380 24/18722 0.388869437070584 0.520171214780141 RAB27A 1 GO:0060479 lung cell differentiation 1/380 24/18722 0.388869437070584 0.520171214780141 KLF2 1 GO:0060571 morphogenesis of an epithelial fold 1/380 24/18722 0.388869437070584 0.520171214780141 HIF1A 1 GO:0061162 establishment of monopolar cell polarity 1/380 24/18722 0.388869437070584 0.520171214780141 MSN 1 GO:0070935 3'-UTR-mediated mRNA stabilization 1/380 24/18722 0.388869437070584 0.520171214780141 ZFP36 1 GO:0071294 cellular response to zinc ion 1/380 24/18722 0.388869437070584 0.520171214780141 TSPO 1 GO:0071676 negative regulation of mononuclear cell migration 1/380 24/18722 0.388869437070584 0.520171214780141 DUSP1 1 GO:0072530 purine-containing compound transmembrane transport 1/380 24/18722 0.388869437070584 0.520171214780141 AQP9 1 GO:0120255 olefinic compound biosynthetic process 1/380 24/18722 0.388869437070584 0.520171214780141 EGR1 1 GO:1903861 positive regulation of dendrite extension 1/380 24/18722 0.388869437070584 0.520171214780141 CXCR4 1 GO:2000209 regulation of anoikis 1/380 24/18722 0.388869437070584 0.520171214780141 MCL1 1 GO:2000310 regulation of NMDA receptor activity 1/380 24/18722 0.388869437070584 0.520171214780141 IFNGR2 1 GO:2001026 regulation of endothelial cell chemotaxis 1/380 24/18722 0.388869437070584 0.520171214780141 TMSB4X 1 GO:0009913 epidermal cell differentiation 5/380 202/18722 0.390967664445722 0.522647745873621 ZFP36/TXNIP/STK4/ZFP36L1/FOSL2 5 GO:1903046 meiotic cell cycle process 5/380 202/18722 0.390967664445722 0.522647745873621 ACTR2/PRKAR1A/ACTR3/UBE2B/MYH9 5 GO:0015718 monocarboxylic acid transport 3/380 111/18722 0.392324391779784 0.523965247299711 AQP9/IL1B/SLC16A3 3 GO:0071867 response to monoamine 3/380 111/18722 0.392324391779784 0.523965247299711 LRRK2/ARRB2/MAPK1 3 GO:0071869 response to catecholamine 3/380 111/18722 0.392324391779784 0.523965247299711 LRRK2/ARRB2/MAPK1 3 GO:0007030 Golgi organization 4/380 157/18722 0.395079575507404 0.527478563138038 LRRK2/VMP1/YWHAZ/MAPK1 4 GO:0010517 regulation of phospholipase activity 2/380 67/18722 0.395744208493072 0.527700479523979 RGS2/C5AR1 2 GO:0048814 regulation of dendrite morphogenesis 2/380 67/18722 0.395744208493072 0.527700479523979 ACTR2/PPP3CA 2 GO:0051306 mitotic sister chromatid separation 2/380 67/18722 0.395744208493072 0.527700479523979 DUSP1/CUL3 2 GO:0061371 determination of heart left/right asymmetry 2/380 67/18722 0.395744208493072 0.527700479523979 TGFBR2/HIF1A 2 GO:0009141 nucleoside triphosphate metabolic process 3/380 112/18722 0.397803075029559 0.529427061932369 LRRK2/TMSB4X/STAT3 3 GO:0035601 protein deacylation 3/380 112/18722 0.397803075029559 0.529427061932369 LRRK2/BCL6/KDM5A 3 GO:0001964 startle response 1/380 25/18722 0.401289461346613 0.529427061932369 PTEN 1 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 1/380 25/18722 0.401289461346613 0.529427061932369 CYBA 1 GO:0003094 glomerular filtration 1/380 25/18722 0.401289461346613 0.529427061932369 CYBA 1 GO:0007288 sperm axoneme assembly 1/380 25/18722 0.401289461346613 0.529427061932369 UBE2B 1 GO:0010954 positive regulation of protein processing 1/380 25/18722 0.401289461346613 0.529427061932369 MYH9 1 GO:0015874 norepinephrine transport 1/380 25/18722 0.401289461346613 0.529427061932369 ACTB 1 GO:0021846 cell proliferation in forebrain 1/380 25/18722 0.401289461346613 0.529427061932369 NUMB 1 GO:0030318 melanocyte differentiation 1/380 25/18722 0.401289461346613 0.529427061932369 RAB27A 1 GO:0032400 melanosome localization 1/380 25/18722 0.401289461346613 0.529427061932369 RAB27A 1 GO:0032469 endoplasmic reticulum calcium ion homeostasis 1/380 25/18722 0.401289461346613 0.529427061932369 GRINA 1 GO:0033119 negative regulation of RNA splicing 1/380 25/18722 0.401289461346613 0.529427061932369 PTBP3 1 GO:0033233 regulation of protein sumoylation 1/380 25/18722 0.401289461346613 0.529427061932369 EGR1 1 GO:0033622 integrin activation 1/380 25/18722 0.401289461346613 0.529427061932369 PLEK 1 GO:0045109 intermediate filament organization 1/380 25/18722 0.401289461346613 0.529427061932369 VIM 1 GO:0045324 late endosome to vacuole transport 1/380 25/18722 0.401289461346613 0.529427061932369 TMEM50A 1 GO:0046039 GTP metabolic process 1/380 25/18722 0.401289461346613 0.529427061932369 LRRK2 1 GO:0050927 positive regulation of positive chemotaxis 1/380 25/18722 0.401289461346613 0.529427061932369 CXCL8 1 GO:0051450 myoblast proliferation 1/380 25/18722 0.401289461346613 0.529427061932369 MALAT1 1 GO:0051788 response to misfolded protein 1/380 25/18722 0.401289461346613 0.529427061932369 CUL3 1 GO:0060706 cell differentiation involved in embryonic placenta development 1/380 25/18722 0.401289461346613 0.529427061932369 STK4 1 GO:0061339 establishment or maintenance of monopolar cell polarity 1/380 25/18722 0.401289461346613 0.529427061932369 MSN 1 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 1/380 25/18722 0.401289461346613 0.529427061932369 HSPA1A 1 GO:0072207 metanephric epithelium development 1/380 25/18722 0.401289461346613 0.529427061932369 CXCR2 1 GO:0090330 regulation of platelet aggregation 1/380 25/18722 0.401289461346613 0.529427061932369 LYN 1 GO:0120316 sperm flagellum assembly 1/380 25/18722 0.401289461346613 0.529427061932369 UBE2B 1 GO:0140448 signaling receptor ligand precursor processing 1/380 25/18722 0.401289461346613 0.529427061932369 MME 1 GO:1901798 positive regulation of signal transduction by p53 class mediator 1/380 25/18722 0.401289461346613 0.529427061932369 DDX5 1 GO:1903055 positive regulation of extracellular matrix organization 1/380 25/18722 0.401289461346613 0.529427061932369 CFLAR 1 GO:1903792 negative regulation of anion transport 1/380 25/18722 0.401289461346613 0.529427061932369 RGS2 1 GO:1903959 regulation of anion transmembrane transport 1/380 25/18722 0.401289461346613 0.529427061932369 RGS2 1 GO:1904753 negative regulation of vascular associated smooth muscle cell migration 1/380 25/18722 0.401289461346613 0.529427061932369 NFE2L2 1 GO:1905564 positive regulation of vascular endothelial cell proliferation 1/380 25/18722 0.401289461346613 0.529427061932369 STAT3 1 GO:0007585 respiratory gaseous exchange by respiratory system 2/380 68/18722 0.4028905557651 0.530712753861648 CSF2RB/YWHAZ 2 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 2/380 68/18722 0.4028905557651 0.530712753861648 TMSB4X/STAT3 2 GO:0010812 negative regulation of cell-substrate adhesion 2/380 68/18722 0.4028905557651 0.530712753861648 BCL6/PTEN 2 GO:0051148 negative regulation of muscle cell differentiation 2/380 68/18722 0.4028905557651 0.530712753861648 RGS2/PAK1 2 GO:0051926 negative regulation of calcium ion transport 2/380 68/18722 0.4028905557651 0.530712753861648 PTGS2/LILRB2 2 GO:0044106 cellular amine metabolic process 3/380 113/18722 0.403268366001976 0.531045251871384 ITGB2/SAT1/OAZ1 3 GO:0009117 nucleotide metabolic process 11/380 489/18722 0.407337645526763 0.536237155363955 NAMPT/LRRK2/ACSL1/CDA/TMSB4X/ELOVL5/TYMP/STAT3/NADK/HIF1A/MAPK1 11 GO:0006936 muscle contraction 8/380 347/18722 0.407789506400311 0.536665183221044 PTGS2/RGS2/PROK2/CXCR4/TPM3/MYL6/TMOD3/DOCK5 8 GO:0008654 phospholipid biosynthetic process 6/380 253/18722 0.408111044226542 0.536754742950125 MBOAT7/PTEN/LPGAT1/FAM126B/LPCAT2/PLSCR1 6 GO:0060828 regulation of canonical Wnt signaling pathway 6/380 253/18722 0.408111044226542 0.536754742950125 LRRK2/STK4/EGR1/UBE2B/TLE3/DDX3X 6 GO:1903008 organelle disassembly 3/380 114/18722 0.408719414296456 0.537279368105186 TSPO/BNIP3L/HIF1A 3 GO:0043271 negative regulation of ion transport 4/380 160/18722 0.40881793282736 0.537279368105186 PTGS2/RGS2/LILRB2/PTEN 4 GO:0003143 embryonic heart tube morphogenesis 2/380 69/18722 0.409996591769194 0.537279368105186 TGFBR2/HIF1A 2 GO:0009145 purine nucleoside triphosphate biosynthetic process 2/380 69/18722 0.409996591769194 0.537279368105186 TMSB4X/STAT3 2 GO:1904377 positive regulation of protein localization to cell periphery 2/380 69/18722 0.409996591769194 0.537279368105186 STX3/RHOG 2 GO:0034765 regulation of ion transmembrane transport 11/380 491/18722 0.412535784240757 0.537279368105186 RGS2/LYN/CTSS/KCNJ15/TMSB4X/CORO1A/CYBA/PTEN/VMP1/IFNGR2/PTPN6 11 GO:0001573 ganglioside metabolic process 1/380 26/18722 0.413457723885431 0.537279368105186 ST8SIA4 1 GO:0002092 positive regulation of receptor internalization 1/380 26/18722 0.413457723885431 0.537279368105186 ARRB2 1 GO:0002418 immune response to tumor cell 1/380 26/18722 0.413457723885431 0.537279368105186 HLA-A 1 GO:0002710 negative regulation of T cell mediated immunity 1/380 26/18722 0.413457723885431 0.537279368105186 PTPRC 1 GO:0003416 endochondral bone growth 1/380 26/18722 0.413457723885431 0.537279368105186 TGFBR2 1 GO:0006706 steroid catabolic process 1/380 26/18722 0.413457723885431 0.537279368105186 HSD17B11 1 GO:0009435 NAD biosynthetic process 1/380 26/18722 0.413457723885431 0.537279368105186 NAMPT 1 GO:0014829 vascular associated smooth muscle contraction 1/380 26/18722 0.413457723885431 0.537279368105186 DOCK5 1 GO:0021680 cerebellar Purkinje cell layer development 1/380 26/18722 0.413457723885431 0.537279368105186 AGTPBP1 1 GO:0021952 central nervous system projection neuron axonogenesis 1/380 26/18722 0.413457723885431 0.537279368105186 NIN 1 GO:0033522 histone H2A ubiquitination 1/380 26/18722 0.413457723885431 0.537279368105186 UBE2B 1 GO:0034063 stress granule assembly 1/380 26/18722 0.413457723885431 0.537279368105186 DDX3X 1 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 1/380 26/18722 0.413457723885431 0.537279368105186 HSPA1A 1 GO:0043094 cellular metabolic compound salvage 1/380 26/18722 0.413457723885431 0.537279368105186 CDA 1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 1/380 26/18722 0.413457723885431 0.537279368105186 HLA-E 1 GO:0046639 negative regulation of alpha-beta T cell differentiation 1/380 26/18722 0.413457723885431 0.537279368105186 BCL6 1 GO:0046755 viral budding 1/380 26/18722 0.413457723885431 0.537279368105186 VPS4B 1 GO:0048499 synaptic vesicle membrane organization 1/380 26/18722 0.413457723885431 0.537279368105186 STX3 1 GO:0048668 collateral sprouting 1/380 26/18722 0.413457723885431 0.537279368105186 NIN 1 GO:0050926 regulation of positive chemotaxis 1/380 26/18722 0.413457723885431 0.537279368105186 CXCL8 1 GO:0051016 barbed-end actin filament capping 1/380 26/18722 0.413457723885431 0.537279368105186 CAPZA1 1 GO:0051350 negative regulation of lyase activity 1/380 26/18722 0.413457723885431 0.537279368105186 P2RY13 1 GO:0051875 pigment granule localization 1/380 26/18722 0.413457723885431 0.537279368105186 RAB27A 1 GO:0070193 synaptonemal complex organization 1/380 26/18722 0.413457723885431 0.537279368105186 UBE2B 1 GO:0070977 bone maturation 1/380 26/18722 0.413457723885431 0.537279368105186 SNX10 1 GO:0097066 response to thyroid hormone 1/380 26/18722 0.413457723885431 0.537279368105186 CTSS 1 GO:0097186 amelogenesis 1/380 26/18722 0.413457723885431 0.537279368105186 CSF3R 1 GO:0097205 renal filtration 1/380 26/18722 0.413457723885431 0.537279368105186 CYBA 1 GO:0099637 neurotransmitter receptor transport 1/380 26/18722 0.413457723885431 0.537279368105186 STX3 1 GO:1901071 glucosamine-containing compound metabolic process 1/380 26/18722 0.413457723885431 0.537279368105186 CTBS 1 GO:1904861 excitatory synapse assembly 1/380 26/18722 0.413457723885431 0.537279368105186 PTEN 1 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 1/380 26/18722 0.413457723885431 0.537279368105186 SOD2 1 GO:2000050 regulation of non-canonical Wnt signaling pathway 1/380 26/18722 0.413457723885431 0.537279368105186 RNF213 1 GO:0016055 Wnt signaling pathway 10/380 444/18722 0.41414587672905 0.538008523910285 LRRK2/FRAT2/PTEN/STK4/EGR1/UBE2B/TLE3/DDX3X/CUL3/RNF213 10 GO:0006836 neurotransmitter transport 5/380 208/18722 0.41506056186658 0.539031425791158 LRRK2/PRKCB/STX3/MCTP2/STXBP3 5 GO:0006338 chromatin remodeling 6/380 255/18722 0.415340256723041 0.539229303256308 ACTB/KDM6B/KDM5A/BAZ2B/PAK1/UBN1 6 GO:0070830 bicellular tight junction assembly 2/380 70/18722 0.417061007956987 0.541297385442183 PECAM1/PAK2 2 GO:0060070 canonical Wnt signaling pathway 7/380 303/18722 0.418184315758594 0.542589024888985 LRRK2/PTEN/STK4/EGR1/UBE2B/TLE3/DDX3X 7 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 6/380 256/18722 0.418951443300067 0.54341787515338 SORL1/LRG1/SDCBP/UBE2D1/UBE2D3/HSPA1A 6 GO:0098732 macromolecule deacylation 3/380 116/18722 0.419575492574467 0.543944827753545 LRRK2/BCL6/KDM5A 3 GO:0198738 cell-cell signaling by wnt 10/380 446/18722 0.419614581409878 0.543944827753545 LRRK2/FRAT2/PTEN/STK4/EGR1/UBE2B/TLE3/DDX3X/CUL3/RNF213 10 GO:0007623 circadian rhythm 5/380 210/18722 0.423062165828354 0.545738078899234 NAMPT/PTEN/EGR1/NFIL3/KDM5A 5 GO:0003208 cardiac ventricle morphogenesis 2/380 71/18722 0.424082565189146 0.545738078899234 TGFBR2/HIF1A 2 GO:0008344 adult locomotory behavior 2/380 71/18722 0.424082565189146 0.545738078899234 ARRB2/AGTPBP1 2 GO:0150116 regulation of cell-substrate junction organization 2/380 71/18722 0.424082565189146 0.545738078899234 PTEN/IQGAP1 2 GO:0051225 spindle assembly 3/380 117/18722 0.424978932484775 0.545738078899234 STAG2/HSPA1A/VPS4B 3 GO:0000737 DNA catabolic process, endonucleolytic 1/380 27/18722 0.42537931486337 0.545738078899234 DICER1 1 GO:0001958 endochondral ossification 1/380 27/18722 0.42537931486337 0.545738078899234 ALPL 1 GO:0003171 atrioventricular valve development 1/380 27/18722 0.42537931486337 0.545738078899234 TGFBR2 1 GO:0003272 endocardial cushion formation 1/380 27/18722 0.42537931486337 0.545738078899234 TGFBR2 1 GO:0006783 heme biosynthetic process 1/380 27/18722 0.42537931486337 0.545738078899234 TSPO 1 GO:0007263 nitric oxide mediated signal transduction 1/380 27/18722 0.42537931486337 0.545738078899234 FPR1 1 GO:0009651 response to salt stress 1/380 27/18722 0.42537931486337 0.545738078899234 ZFP36L1 1 GO:0010528 regulation of transposition 1/380 27/18722 0.42537931486337 0.545738078899234 APOBEC3A 1 GO:0010529 negative regulation of transposition 1/380 27/18722 0.42537931486337 0.545738078899234 APOBEC3A 1 GO:0010561 negative regulation of glycoprotein biosynthetic process 1/380 27/18722 0.42537931486337 0.545738078899234 ITM2B 1 GO:0010586 miRNA metabolic process 1/380 27/18722 0.42537931486337 0.545738078899234 DICER1 1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 1/380 27/18722 0.42537931486337 0.545738078899234 VPS4B 1 GO:0014850 response to muscle activity 1/380 27/18722 0.42537931486337 0.545738078899234 HIF1A 1 GO:0018126 protein hydroxylation 1/380 27/18722 0.42537931486337 0.545738078899234 EGLN1 1 GO:0034505 tooth mineralization 1/380 27/18722 0.42537931486337 0.545738078899234 ALPL 1 GO:0035235 ionotropic glutamate receptor signaling pathway 1/380 27/18722 0.42537931486337 0.545738078899234 CPEB4 1 GO:0035459 vesicle cargo loading 1/380 27/18722 0.42537931486337 0.545738078899234 PICALM 1 GO:0036075 replacement ossification 1/380 27/18722 0.42537931486337 0.545738078899234 ALPL 1 GO:0042104 positive regulation of activated T cell proliferation 1/380 27/18722 0.42537931486337 0.545738078899234 PYCARD 1 GO:0042402 cellular biogenic amine catabolic process 1/380 27/18722 0.42537931486337 0.545738078899234 SAT1 1 GO:0045830 positive regulation of isotype switching 1/380 27/18722 0.42537931486337 0.545738078899234 PTPRC 1 GO:0046174 polyol catabolic process 1/380 27/18722 0.42537931486337 0.545738078899234 PTEN 1 GO:0048873 homeostasis of number of cells within a tissue 1/380 27/18722 0.42537931486337 0.545738078899234 CORO1A 1 GO:0051953 negative regulation of amine transport 1/380 27/18722 0.42537931486337 0.545738078899234 RGS2 1 GO:0070861 regulation of protein exit from endoplasmic reticulum 1/380 27/18722 0.42537931486337 0.545738078899234 SORL1 1 GO:1903319 positive regulation of protein maturation 1/380 27/18722 0.42537931486337 0.545738078899234 MYH9 1 GO:1903421 regulation of synaptic vesicle recycling 1/380 27/18722 0.42537931486337 0.545738078899234 LRRK2 1 GO:1903859 regulation of dendrite extension 1/380 27/18722 0.42537931486337 0.545738078899234 CXCR4 1 GO:2000463 positive regulation of excitatory postsynaptic potential 1/380 27/18722 0.42537931486337 0.545738078899234 PTEN 1 GO:0046474 glycerophospholipid biosynthetic process 5/380 211/18722 0.42705575772596 0.547722935787232 MBOAT7/PTEN/FAM126B/LPCAT2/PLSCR1 5 GO:0006753 nucleoside phosphate metabolic process 11/380 497/18722 0.42813465406759 0.54894043596011 NAMPT/LRRK2/ACSL1/CDA/TMSB4X/ELOVL5/TYMP/STAT3/NADK/HIF1A/MAPK1 11 GO:0006413 translational initiation 3/380 118/18722 0.43036494915358 0.551299322342834 EIF1/DDX3X/PPP1R15A 3 GO:0009308 amine metabolic process 3/380 118/18722 0.43036494915358 0.551299322342834 ITGB2/SAT1/OAZ1 3 GO:0051101 regulation of DNA binding 3/380 118/18722 0.43036494915358 0.551299322342834 TMSB4X/PLAUR/IFI16 3 GO:0001707 mesoderm formation 2/380 72/18722 0.431060091470027 0.551522503738842 KDM6B/PRKAR1A 2 GO:0033045 regulation of sister chromatid segregation 2/380 72/18722 0.431060091470027 0.551522503738842 DUSP1/CUL3 2 GO:0051057 positive regulation of small GTPase mediated signal transduction 2/380 72/18722 0.431060091470027 0.551522503738842 GPR65/SOS2 2 GO:1901880 negative regulation of protein depolymerization 2/380 72/18722 0.431060091470027 0.551522503738842 CAPZA1/TMOD3 2 GO:0002313 mature B cell differentiation involved in immune response 1/380 28/18722 0.43705922180918 0.555839580889452 SPI1 1 GO:0006515 protein quality control for misfolded or incompletely synthesized proteins 1/380 28/18722 0.43705922180918 0.555839580889452 CUL3 1 GO:0009065 glutamine family amino acid catabolic process 1/380 28/18722 0.43705922180918 0.555839580889452 GLUL 1 GO:0010464 regulation of mesenchymal cell proliferation 1/380 28/18722 0.43705922180918 0.555839580889452 TGFBR2 1 GO:0030262 apoptotic nuclear changes 1/380 28/18722 0.43705922180918 0.555839580889452 DICER1 1 GO:0031440 regulation of mRNA 3'-end processing 1/380 28/18722 0.43705922180918 0.555839580889452 ZFP36L1 1 GO:0032438 melanosome organization 1/380 28/18722 0.43705922180918 0.555839580889452 LYST 1 GO:0032607 interferon-alpha production 1/380 28/18722 0.43705922180918 0.555839580889452 DDX3X 1 GO:0032647 regulation of interferon-alpha production 1/380 28/18722 0.43705922180918 0.555839580889452 DDX3X 1 GO:0032958 inositol phosphate biosynthetic process 1/380 28/18722 0.43705922180918 0.555839580889452 PLEK 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/380 28/18722 0.43705922180918 0.555839580889452 RAB7A 1 GO:0042983 amyloid precursor protein biosynthetic process 1/380 28/18722 0.43705922180918 0.555839580889452 ITM2B 1 GO:0042984 regulation of amyloid precursor protein biosynthetic process 1/380 28/18722 0.43705922180918 0.555839580889452 ITM2B 1 GO:0045671 negative regulation of osteoclast differentiation 1/380 28/18722 0.43705922180918 0.555839580889452 LILRB3 1 GO:0050996 positive regulation of lipid catabolic process 1/380 28/18722 0.43705922180918 0.555839580889452 IL1B 1 GO:0051894 positive regulation of focal adhesion assembly 1/380 28/18722 0.43705922180918 0.555839580889452 IQGAP1 1 GO:0060259 regulation of feeding behavior 1/380 28/18722 0.43705922180918 0.555839580889452 STAT3 1 GO:0060765 regulation of androgen receptor signaling pathway 1/380 28/18722 0.43705922180918 0.555839580889452 DDX5 1 GO:0071280 cellular response to copper ion 1/380 28/18722 0.43705922180918 0.555839580889452 NFE2L2 1 GO:1903672 positive regulation of sprouting angiogenesis 1/380 28/18722 0.43705922180918 0.555839580889452 JAK1 1 GO:0006073 cellular glucan metabolic process 2/380 73/18722 0.437992479745303 0.556358173881631 MGAM/PYGL 2 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 2/380 73/18722 0.437992479745303 0.556358173881631 NADK/HIF1A 2 GO:0044042 glucan metabolic process 2/380 73/18722 0.437992479745303 0.556358173881631 MGAM/PYGL 2 GO:0072089 stem cell proliferation 2/380 73/18722 0.437992479745303 0.556358173881631 PTPRC/ZFP36L1 2 GO:0072330 monocarboxylic acid biosynthetic process 5/380 214/18722 0.439003323222471 0.557474984661818 PTGS2/ELOVL5/ALOX5/IL1B/LPGAT1 5 GO:0034767 positive regulation of ion transmembrane transport 4/380 167/18722 0.440604158641502 0.559340111464856 CTSS/TMSB4X/VMP1/IFNGR2 4 GO:0007052 mitotic spindle organization 3/380 120/18722 0.441081770319697 0.55977863269521 STAG2/HSPA1A/VPS4B 3 GO:0043588 skin development 6/380 263/18722 0.44413970820041 0.563078671308301 LTB/ZFP36/TXNIP/STK4/ZFP36L1/FOSL2 6 GO:0003151 outflow tract morphogenesis 2/380 74/18722 0.444878685760939 0.563078671308301 TGFBR2/HIF1A 2 GO:0009201 ribonucleoside triphosphate biosynthetic process 2/380 74/18722 0.444878685760939 0.563078671308301 TMSB4X/STAT3 2 GO:0030968 endoplasmic reticulum unfolded protein response 2/380 74/18722 0.444878685760939 0.563078671308301 PPP1R15A/NFE2L2 2 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 2/380 74/18722 0.444878685760939 0.563078671308301 DDX5/PAK1 2 GO:0046470 phosphatidylcholine metabolic process 2/380 74/18722 0.444878685760939 0.563078671308301 MBOAT7/LPCAT2 2 GO:0048332 mesoderm morphogenesis 2/380 74/18722 0.444878685760939 0.563078671308301 KDM6B/PRKAR1A 2 GO:0070972 protein localization to endoplasmic reticulum 2/380 74/18722 0.444878685760939 0.563078671308301 LRRK2/PPP1R15A 2 GO:0120192 tight junction assembly 2/380 74/18722 0.444878685760939 0.563078671308301 PECAM1/PAK2 2 GO:0001838 embryonic epithelial tube formation 3/380 121/18722 0.446411156472452 0.563455168975567 STK4/VASP/HIF1A 3 GO:0002455 humoral immune response mediated by circulating immunoglobulin 3/380 121/18722 0.446411156472452 0.563455168975567 PTPRC/CD55/PTPN6 3 GO:0042177 negative regulation of protein catabolic process 3/380 121/18722 0.446411156472452 0.563455168975567 IRAK3/SDCBP/N4BP1 3 GO:0002377 immunoglobulin production 5/380 216/18722 0.446937149821484 0.563455168975567 PTPRC/BCL6/B2M/HLA-E/NBN 5 GO:0006688 glycosphingolipid biosynthetic process 1/380 29/18722 0.448502331668627 0.563455168975567 ST8SIA4 1 GO:0007143 female meiotic nuclear division 1/380 29/18722 0.448502331668627 0.563455168975567 PRKAR1A 1 GO:0009310 amine catabolic process 1/380 29/18722 0.448502331668627 0.563455168975567 SAT1 1 GO:0019433 triglyceride catabolic process 1/380 29/18722 0.448502331668627 0.563455168975567 SORL1 1 GO:0022011 myelination in peripheral nervous system 1/380 29/18722 0.448502331668627 0.563455168975567 DICER1 1 GO:0032292 peripheral nervous system axon ensheathment 1/380 29/18722 0.448502331668627 0.563455168975567 DICER1 1 GO:0034067 protein localization to Golgi apparatus 1/380 29/18722 0.448502331668627 0.563455168975567 SORL1 1 GO:0035066 positive regulation of histone acetylation 1/380 29/18722 0.448502331668627 0.563455168975567 IL1B 1 GO:0042759 long-chain fatty acid biosynthetic process 1/380 29/18722 0.448502331668627 0.563455168975567 ALOX5 1 GO:0048265 response to pain 1/380 29/18722 0.448502331668627 0.563455168975567 TSPO 1 GO:0048679 regulation of axon regeneration 1/380 29/18722 0.448502331668627 0.563455168975567 PTEN 1 GO:0048753 pigment granule organization 1/380 29/18722 0.448502331668627 0.563455168975567 LYST 1 GO:0051873 killing by host of symbiont cells 1/380 29/18722 0.448502331668627 0.563455168975567 TREM1 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/380 29/18722 0.448502331668627 0.563455168975567 TREM1 1 GO:0071549 cellular response to dexamethasone stimulus 1/380 29/18722 0.448502331668627 0.563455168975567 CFLAR 1 GO:0090114 COPII-coated vesicle budding 1/380 29/18722 0.448502331668627 0.563455168975567 CUL3 1 GO:0098868 bone growth 1/380 29/18722 0.448502331668627 0.563455168975567 TGFBR2 1 GO:1900117 regulation of execution phase of apoptosis 1/380 29/18722 0.448502331668627 0.563455168975567 PAK2 1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 1/380 29/18722 0.448502331668627 0.563455168975567 PTEN 1 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/380 29/18722 0.448502331668627 0.563455168975567 CD44 1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining 1/380 29/18722 0.448502331668627 0.563455168975567 SMCHD1 1 GO:0006937 regulation of muscle contraction 4/380 169/18722 0.449598185941386 0.564496981162695 PTGS2/RGS2/PROK2/DOCK5 4 GO:0009152 purine ribonucleotide biosynthetic process 4/380 169/18722 0.449598185941386 0.564496981162695 ACSL1/TMSB4X/ELOVL5/STAT3 4 GO:1902369 negative regulation of RNA catabolic process 2/380 75/18722 0.451717725981947 0.566489604742628 ZFP36/SLC11A1 2 GO:1903363 negative regulation of cellular protein catabolic process 2/380 75/18722 0.451717725981947 0.566489604742628 SDCBP/N4BP1 2 GO:0031109 microtubule polymerization or depolymerization 3/380 122/18722 0.451720282223343 0.566489604742628 NIN/HSPA1A/PAK1 3 GO:0051928 positive regulation of calcium ion transport 3/380 122/18722 0.451720282223343 0.566489604742628 ARRB2/TSPO/VMP1 3 GO:0030178 negative regulation of Wnt signaling pathway 4/380 170/18722 0.45407818063962 0.569278003258967 STK4/EGR1/TLE3/RNF213 4 GO:0046394 carboxylic acid biosynthetic process 7/380 314/18722 0.454508940853277 0.569649412404152 PTGS2/ALOX5AP/ELOVL5/ALOX5/IL1B/LPGAT1/GLUL 7 GO:0042445 hormone metabolic process 5/380 218/18722 0.454842790957962 0.569899177428097 TSPO/EGR1/HSD17B11/HIF1A/MME 5 GO:0006305 DNA alkylation 2/380 76/18722 0.458508675569388 0.570934424640812 SPI1/FOS 2 GO:0006306 DNA methylation 2/380 76/18722 0.458508675569388 0.570934424640812 SPI1/FOS 2 GO:0071426 ribonucleoprotein complex export from nucleus 2/380 76/18722 0.458508675569388 0.570934424640812 NUP214/ZC3H11A 2 GO:0003299 muscle hypertrophy in response to stress 1/380 30/18722 0.459713432827667 0.570934424640812 PPP3CA 1 GO:0006921 cellular component disassembly involved in execution phase of apoptosis 1/380 30/18722 0.459713432827667 0.570934424640812 DICER1 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/380 30/18722 0.459713432827667 0.570934424640812 NCF1 1 GO:0007202 activation of phospholipase C activity 1/380 30/18722 0.459713432827667 0.570934424640812 C5AR1 1 GO:0008209 androgen metabolic process 1/380 30/18722 0.459713432827667 0.570934424640812 HSD17B11 1 GO:0009264 deoxyribonucleotide catabolic process 1/380 30/18722 0.459713432827667 0.570934424640812 TYMP 1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 1/380 30/18722 0.459713432827667 0.570934424640812 MAPK1 1 GO:0014887 cardiac muscle adaptation 1/380 30/18722 0.459713432827667 0.570934424640812 PPP3CA 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/380 30/18722 0.459713432827667 0.570934424640812 PPP3CA 1 GO:0015721 bile acid and bile salt transport 1/380 30/18722 0.459713432827667 0.570934424640812 AQP9 1 GO:0019674 NAD metabolic process 1/380 30/18722 0.459713432827667 0.570934424640812 NADK 1 GO:0032480 negative regulation of type I interferon production 1/380 30/18722 0.459713432827667 0.570934424640812 PYCARD 1 GO:0036258 multivesicular body assembly 1/380 30/18722 0.459713432827667 0.570934424640812 VPS4B 1 GO:0036296 response to increased oxygen levels 1/380 30/18722 0.459713432827667 0.570934424640812 CAT 1 GO:0043032 positive regulation of macrophage activation 1/380 30/18722 0.459713432827667 0.570934424640812 LRRK2 1 GO:0044030 regulation of DNA methylation 1/380 30/18722 0.459713432827667 0.570934424640812 SPI1 1 GO:0044788 modulation by host of viral process 1/380 30/18722 0.459713432827667 0.570934424640812 IGF2R 1 GO:0046825 regulation of protein export from nucleus 1/380 30/18722 0.459713432827667 0.570934424640812 IL1B 1 GO:0048147 negative regulation of fibroblast proliferation 1/380 30/18722 0.459713432827667 0.570934424640812 FTH1 1 GO:0048799 animal organ maturation 1/380 30/18722 0.459713432827667 0.570934424640812 SNX10 1 GO:0060351 cartilage development involved in endochondral bone morphogenesis 1/380 30/18722 0.459713432827667 0.570934424640812 TGFBR2 1 GO:0099068 postsynapse assembly 1/380 30/18722 0.459713432827667 0.570934424640812 PTEN 1 GO:0140058 neuron projection arborization 1/380 30/18722 0.459713432827667 0.570934424640812 LRRK2 1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 1/380 30/18722 0.459713432827667 0.570934424640812 PPP1R15A 1 GO:1902751 positive regulation of cell cycle G2/M phase transition 1/380 30/18722 0.459713432827667 0.570934424640812 VPS4B 1 GO:1903019 negative regulation of glycoprotein metabolic process 1/380 30/18722 0.459713432827667 0.570934424640812 ITM2B 1 GO:2000648 positive regulation of stem cell proliferation 1/380 30/18722 0.459713432827667 0.570934424640812 PTPRC 1 GO:0016053 organic acid biosynthetic process 7/380 316/18722 0.461071251863688 0.572452873539349 PTGS2/ALOX5AP/ELOVL5/ALOX5/IL1B/LPGAT1/GLUL 7 GO:0000380 alternative mRNA splicing, via spliceosome 2/380 77/18722 0.465250666414121 0.577303419942515 CELF2/DDX5 2 GO:0071166 ribonucleoprotein complex localization 2/380 77/18722 0.465250666414121 0.577303419942515 NUP214/ZC3H11A 2 GO:0010469 regulation of signaling receptor activity 4/380 173/18722 0.4674447105666 0.579477533255068 NCF1/PTEN/IFNGR2/HIF1A 4 GO:0002063 chondrocyte development 1/380 31/18722 0.470697217095026 0.579477533255068 TGFBR2 1 GO:0002230 positive regulation of defense response to virus by host 1/380 31/18722 0.470697217095026 0.579477533255068 PYCARD 1 GO:0002717 positive regulation of natural killer cell mediated immunity 1/380 31/18722 0.470697217095026 0.579477533255068 HLA-E 1 GO:0002828 regulation of type 2 immune response 1/380 31/18722 0.470697217095026 0.579477533255068 BCL6 1 GO:0006779 porphyrin-containing compound biosynthetic process 1/380 31/18722 0.470697217095026 0.579477533255068 TSPO 1 GO:0007190 activation of adenylate cyclase activity 1/380 31/18722 0.470697217095026 0.579477533255068 CAP1 1 GO:0018200 peptidyl-glutamic acid modification 1/380 31/18722 0.470697217095026 0.579477533255068 AGTPBP1 1 GO:0032148 activation of protein kinase B activity 1/380 31/18722 0.470697217095026 0.579477533255068 OSBPL8 1 GO:0033014 tetrapyrrole biosynthetic process 1/380 31/18722 0.470697217095026 0.579477533255068 TSPO 1 GO:0033238 regulation of cellular amine metabolic process 1/380 31/18722 0.470697217095026 0.579477533255068 ITGB2 1 GO:0042133 neurotransmitter metabolic process 1/380 31/18722 0.470697217095026 0.579477533255068 AGTPBP1 1 GO:0043171 peptide catabolic process 1/380 31/18722 0.470697217095026 0.579477533255068 NPEPPS 1 GO:0046386 deoxyribose phosphate catabolic process 1/380 31/18722 0.470697217095026 0.579477533255068 TYMP 1 GO:0048384 retinoic acid receptor signaling pathway 1/380 31/18722 0.470697217095026 0.579477533255068 KLF2 1 GO:0048566 embryonic digestive tract development 1/380 31/18722 0.470697217095026 0.579477533255068 CXCL8 1 GO:0051443 positive regulation of ubiquitin-protein transferase activity 1/380 31/18722 0.470697217095026 0.579477533255068 PTEN 1 GO:0060045 positive regulation of cardiac muscle cell proliferation 1/380 31/18722 0.470697217095026 0.579477533255068 MAPK1 1 GO:0061099 negative regulation of protein tyrosine kinase activity 1/380 31/18722 0.470697217095026 0.579477533255068 PTPRC 1 GO:0070633 transepithelial transport 1/380 31/18722 0.470697217095026 0.579477533255068 ACTB 1 GO:0070723 response to cholesterol 1/380 31/18722 0.470697217095026 0.579477533255068 TGFBR2 1 GO:0071168 protein localization to chromatin 1/380 31/18722 0.470697217095026 0.579477533255068 SPI1 1 GO:0071711 basement membrane organization 1/380 31/18722 0.470697217095026 0.579477533255068 CTSS 1 GO:0090162 establishment of epithelial cell polarity 1/380 31/18722 0.470697217095026 0.579477533255068 MSN 1 GO:0090183 regulation of kidney development 1/380 31/18722 0.470697217095026 0.579477533255068 BASP1 1 GO:1900027 regulation of ruffle assembly 1/380 31/18722 0.470697217095026 0.579477533255068 RHOG 1 GO:1901797 negative regulation of signal transduction by p53 class mediator 1/380 31/18722 0.470697217095026 0.579477533255068 CD44 1 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 2/380 78/18722 0.471942885225837 0.580167813913329 RGS2/FPR2 2 GO:0035050 embryonic heart tube development 2/380 78/18722 0.471942885225837 0.580167813913329 TGFBR2/HIF1A 2 GO:0043297 apical junction assembly 2/380 78/18722 0.471942885225837 0.580167813913329 PECAM1/PAK2 2 GO:0061045 negative regulation of wound healing 2/380 78/18722 0.471942885225837 0.580167813913329 ALOX5/PTEN 2 GO:1901616 organic hydroxy compound catabolic process 2/380 78/18722 0.471942885225837 0.580167813913329 CYP4F3/PTEN 2 GO:0035270 endocrine system development 3/380 127/18722 0.477939701720369 0.587198908263928 IL6R/TSPO/MAPK1 3 GO:0048565 digestive tract development 3/380 127/18722 0.477939701720369 0.587198908263928 CXCL8/TGFBR2/HIF1A 3 GO:0000245 spliceosomal complex assembly 2/380 79/18722 0.478584571675956 0.587820667357214 CELF2/SF1 2 GO:0003338 metanephros morphogenesis 1/380 32/18722 0.481458281645017 0.588109553725598 BASP1 1 GO:0006308 DNA catabolic process 1/380 32/18722 0.481458281645017 0.588109553725598 DICER1 1 GO:0014044 Schwann cell development 1/380 32/18722 0.481458281645017 0.588109553725598 DICER1 1 GO:0019835 cytolysis 1/380 32/18722 0.481458281645017 0.588109553725598 LYZ 1 GO:0021799 cerebral cortex radially oriented cell migration 1/380 32/18722 0.481458281645017 0.588109553725598 MBOAT7 1 GO:0030431 sleep 1/380 32/18722 0.481458281645017 0.588109553725598 FOS 1 GO:0032196 transposition 1/380 32/18722 0.481458281645017 0.588109553725598 APOBEC3A 1 GO:0033687 osteoblast proliferation 1/380 32/18722 0.481458281645017 0.588109553725598 JUNB 1 GO:0035767 endothelial cell chemotaxis 1/380 32/18722 0.481458281645017 0.588109553725598 TMSB4X 1 GO:0042044 fluid transport 1/380 32/18722 0.481458281645017 0.588109553725598 AQP9 1 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 1/380 32/18722 0.481458281645017 0.588109553725598 NFKBIZ 1 GO:0046856 phosphatidylinositol dephosphorylation 1/380 32/18722 0.481458281645017 0.588109553725598 PTEN 1 GO:0050850 positive regulation of calcium-mediated signaling 1/380 32/18722 0.481458281645017 0.588109553725598 CLEC7A 1 GO:0051642 centrosome localization 1/380 32/18722 0.481458281645017 0.588109553725598 NIN 1 GO:0060317 cardiac epithelial to mesenchymal transition 1/380 32/18722 0.481458281645017 0.588109553725598 TGFBR2 1 GO:0071875 adrenergic receptor signaling pathway 1/380 32/18722 0.481458281645017 0.588109553725598 RGS2 1 GO:0090140 regulation of mitochondrial fission 1/380 32/18722 0.481458281645017 0.588109553725598 LRRK2 1 GO:1901185 negative regulation of ERBB signaling pathway 1/380 32/18722 0.481458281645017 0.588109553725598 RAB7A 1 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 1/380 32/18722 0.481458281645017 0.588109553725598 BCL6 1 GO:0001952 regulation of cell-matrix adhesion 3/380 128/18722 0.483114161317964 0.58979200725903 BCL6/PTEN/IQGAP1 3 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 3/380 128/18722 0.483114161317964 0.58979200725903 LRG1/SDCBP/HSPA1A 3 GO:0098739 import across plasma membrane 4/380 177/18722 0.485079494204203 0.591796139191062 RGS2/ACSL1/KCNJ15/SLC2A3 4 GO:0032204 regulation of telomere maintenance 2/380 80/18722 0.485175016593003 0.591796139191062 MAPK1/NBN 2 GO:0120193 tight junction organization 2/380 80/18722 0.485175016593003 0.591796139191062 PECAM1/PAK2 2 GO:0008544 epidermis development 7/380 324/18722 0.487134101599356 0.594014661754469 ZFP36/TXNIP/WAS/STK4/ZFP36L1/FOSL2/FLOT2 7 GO:0007093 mitotic cell cycle checkpoint signaling 3/380 129/18722 0.488264175874051 0.595221296726139 DUSP1/NABP1/NBN 3 GO:0006109 regulation of carbohydrate metabolic process 4/380 178/18722 0.489452057345035 0.596173044192266 PLEK/MIDN/STAT3/HIF1A 4 GO:0006096 glycolytic process 2/380 81/18722 0.491713560209089 0.596173044192266 STAT3/HIF1A 2 GO:0014032 neural crest cell development 2/380 81/18722 0.491713560209089 0.596173044192266 HIF1A/MAPK1 2 GO:0051149 positive regulation of muscle cell differentiation 2/380 81/18722 0.491713560209089 0.596173044192266 SOD2/ARRB2 2 GO:0001881 receptor recycling 1/380 33/18722 0.492001130921363 0.596173044192266 SORL1 1 GO:0002335 mature B cell differentiation 1/380 33/18722 0.492001130921363 0.596173044192266 SPI1 1 GO:0006336 DNA replication-independent nucleosome assembly 1/380 33/18722 0.492001130921363 0.596173044192266 UBN1 1 GO:0006536 glutamate metabolic process 1/380 33/18722 0.492001130921363 0.596173044192266 GLUL 1 GO:0010259 multicellular organism aging 1/380 33/18722 0.492001130921363 0.596173044192266 LRRK2 1 GO:0021696 cerebellar cortex morphogenesis 1/380 33/18722 0.492001130921363 0.596173044192266 AGTPBP1 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/380 33/18722 0.492001130921363 0.596173044192266 PTEN 1 GO:0035025 positive regulation of Rho protein signal transduction 1/380 33/18722 0.492001130921363 0.596173044192266 GPR65 1 GO:0048333 mesodermal cell differentiation 1/380 33/18722 0.492001130921363 0.596173044192266 KDM6B 1 GO:0050901 leukocyte tethering or rolling 1/380 33/18722 0.492001130921363 0.596173044192266 SELL 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/380 33/18722 0.492001130921363 0.596173044192266 CXCR4 1 GO:0070570 regulation of neuron projection regeneration 1/380 33/18722 0.492001130921363 0.596173044192266 PTEN 1 GO:0071763 nuclear membrane organization 1/380 33/18722 0.492001130921363 0.596173044192266 PRKCB 1 GO:0150117 positive regulation of cell-substrate junction organization 1/380 33/18722 0.492001130921363 0.596173044192266 IQGAP1 1 GO:1901380 negative regulation of potassium ion transmembrane transport 1/380 33/18722 0.492001130921363 0.596173044192266 PTEN 1 GO:1901976 regulation of cell cycle checkpoint 1/380 33/18722 0.492001130921363 0.596173044192266 DUSP1 1 GO:1903715 regulation of aerobic respiration 1/380 33/18722 0.492001130921363 0.596173044192266 HIF1A 1 GO:0006282 regulation of DNA repair 3/380 130/18722 0.493389224546092 0.596660013121845 SMCHD1/WAS/ACTR2 3 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 3/380 130/18722 0.493389224546092 0.596660013121845 SORL1/LRRK2/CUL3 3 GO:0006956 complement activation 3/380 130/18722 0.493389224546092 0.596660013121845 IL1B/FCN1/CD55 3 GO:0015918 sterol transport 3/380 130/18722 0.493389224546092 0.596660013121845 TSPO/OSBPL8/VPS4B 3 GO:0030534 adult behavior 3/380 130/18722 0.493389224546092 0.596660013121845 ARRB2/PTEN/AGTPBP1 3 GO:0042476 odontogenesis 3/380 130/18722 0.493389224546092 0.596660013121845 ALPL/CSF3R/SNX10 3 GO:0043467 regulation of generation of precursor metabolites and energy 3/380 130/18722 0.493389224546092 0.596660013121845 STAT3/HIF1A/IFNAR1 3 GO:0018205 peptidyl-lysine modification 8/380 376/18722 0.49640489255298 0.600135518116435 SPI1/IL1B/MSL1/EGR1/NCOA1/TAF7/TET2/PHF20L1 8 GO:0022898 regulation of transmembrane transporter activity 6/380 278/18722 0.49725236545616 0.600988518181175 CTSS/TMSB4X/ACTB/PTEN/VMP1/IFNGR2 6 GO:0006757 ATP generation from ADP 2/380 82/18722 0.498199590456197 0.601446768980044 STAT3/HIF1A 2 GO:0060395 SMAD protein signal transduction 2/380 82/18722 0.498199590456197 0.601446768980044 FOS/VIM 2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 2/380 82/18722 0.498199590456197 0.601446768980044 RNASET2/DICER1 2 GO:2001252 positive regulation of chromosome organization 2/380 82/18722 0.498199590456197 0.601446768980044 MAPK1/NBN 2 GO:0006661 phosphatidylinositol biosynthetic process 3/380 131/18722 0.498488804928011 0.601453016772115 MBOAT7/PTEN/FAM126B 3 GO:0019827 stem cell population maintenance 3/380 131/18722 0.498488804928011 0.601453016772115 SPI1/ZFP36L2/STAT3 3 GO:0030111 regulation of Wnt signaling pathway 7/380 328/18722 0.500032489426102 0.60180711050512 LRRK2/STK4/EGR1/UBE2B/TLE3/DDX3X/RNF213 7 GO:0048568 embryonic organ development 9/380 427/18722 0.501663091149839 0.60180711050512 CXCL8/JUNB/CEBPB/STK4/ZFP36L1/TGFBR2/NCOA1/HIF1A/MAPK1 9 GO:0006270 DNA replication initiation 1/380 34/18722 0.502330178502822 0.60180711050512 NBN 1 GO:0007095 mitotic G2 DNA damage checkpoint signaling 1/380 34/18722 0.502330178502822 0.60180711050512 NBN 1 GO:0007616 long-term memory 1/380 34/18722 0.502330178502822 0.60180711050512 PJA2 1 GO:0016242 negative regulation of macroautophagy 1/380 34/18722 0.502330178502822 0.60180711050512 LRRK2 1 GO:0032212 positive regulation of telomere maintenance via telomerase 1/380 34/18722 0.502330178502822 0.60180711050512 MAPK1 1 GO:0034724 DNA replication-independent nucleosome organization 1/380 34/18722 0.502330178502822 0.60180711050512 UBN1 1 GO:0035590 purinergic nucleotide receptor signaling pathway 1/380 34/18722 0.502330178502822 0.60180711050512 P2RY13 1 GO:0043276 anoikis 1/380 34/18722 0.502330178502822 0.60180711050512 MCL1 1 GO:0048741 skeletal muscle fiber development 1/380 34/18722 0.502330178502822 0.60180711050512 PPP3CA 1 GO:0048854 brain morphogenesis 1/380 34/18722 0.502330178502822 0.60180711050512 PTEN 1 GO:0050931 pigment cell differentiation 1/380 34/18722 0.502330178502822 0.60180711050512 RAB27A 1 GO:0051085 chaperone cofactor-dependent protein refolding 1/380 34/18722 0.502330178502822 0.60180711050512 HSPA1A 1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 1/380 34/18722 0.502330178502822 0.60180711050512 GPR65 1 GO:0051973 positive regulation of telomerase activity 1/380 34/18722 0.502330178502822 0.60180711050512 MAPK1 1 GO:0070884 regulation of calcineurin-NFAT signaling cascade 1/380 34/18722 0.502330178502822 0.60180711050512 CLEC7A 1 GO:0090075 relaxation of muscle 1/380 34/18722 0.502330178502822 0.60180711050512 RGS2 1 GO:1990000 amyloid fibril formation 1/380 34/18722 0.502330178502822 0.60180711050512 B2M 1 GO:2000352 negative regulation of endothelial cell apoptotic process 1/380 34/18722 0.502330178502822 0.60180711050512 NFE2L2 1 GO:2000758 positive regulation of peptidyl-lysine acetylation 1/380 34/18722 0.502330178502822 0.60180711050512 IL1B 1 GO:2000780 negative regulation of double-strand break repair 1/380 34/18722 0.502330178502822 0.60180711050512 SMCHD1 1 GO:0006479 protein methylation 4/380 181/18722 0.502476964048667 0.60180711050512 BTG2/BTG1/TET2/PCMTD1 4 GO:0008213 protein alkylation 4/380 181/18722 0.502476964048667 0.60180711050512 BTG2/BTG1/TET2/PCMTD1 4 GO:0008361 regulation of cell size 4/380 181/18722 0.502476964048667 0.60180711050512 PLEK/PTEN/MSN/PAK1 4 GO:1905952 regulation of lipid localization 4/380 181/18722 0.502476964048667 0.60180711050512 ACSL1/IL1B/TSPO/OSBPL8 4 GO:0035264 multicellular organism growth 3/380 132/18722 0.50356243277619 0.602766224648718 KLF2/ZFP36L1/STAT3 3 GO:0072175 epithelial tube formation 3/380 132/18722 0.50356243277619 0.602766224648718 STK4/VASP/HIF1A 3 GO:0051899 membrane depolarization 2/380 83/18722 0.504632541310962 0.603876465795967 LRRK2/TSPO 2 GO:0009260 ribonucleotide biosynthetic process 4/380 182/18722 0.506786476297895 0.606282691277284 ACSL1/TMSB4X/ELOVL5/STAT3 4 GO:0006997 nucleus organization 3/380 133/18722 0.508609641733798 0.608291960672871 PRKCB/VPS4B/SF1 3 GO:0010594 regulation of endothelial cell migration 5/380 232/18722 0.509179847890993 0.608801992043579 PTGS2/TMSB4X/GLUL/HIF1A/NFE2L2 5 GO:0002088 lens development in camera-type eye 2/380 84/18722 0.511011891186707 0.60927138874913 VIM/TGFBR2 2 GO:0006405 RNA export from nucleus 2/380 84/18722 0.511011891186707 0.60927138874913 NUP214/ZC3H11A 2 GO:0032370 positive regulation of lipid transport 2/380 84/18722 0.511011891186707 0.60927138874913 ACSL1/IL1B 2 GO:0032508 DNA duplex unwinding 2/380 84/18722 0.511011891186707 0.60927138874913 DDX3X/NBN 2 GO:0042310 vasoconstriction 2/380 84/18722 0.511011891186707 0.60927138874913 PTGS2/DOCK5 2 GO:0015695 organic cation transport 1/380 35/18722 0.512449748931382 0.60927138874913 SEC14L1 1 GO:0019068 virion assembly 1/380 35/18722 0.512449748931382 0.60927138874913 VPS4B 1 GO:0032205 negative regulation of telomere maintenance 1/380 35/18722 0.512449748931382 0.60927138874913 NBN 1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1/380 35/18722 0.512449748931382 0.60927138874913 PAK1 1 GO:0034331 cell junction maintenance 1/380 35/18722 0.512449748931382 0.60927138874913 CD177 1 GO:0043243 positive regulation of protein-containing complex disassembly 1/380 35/18722 0.512449748931382 0.60927138874913 PLEK 1 GO:0045907 positive regulation of vasoconstriction 1/380 35/18722 0.512449748931382 0.60927138874913 PTGS2 1 GO:0046471 phosphatidylglycerol metabolic process 1/380 35/18722 0.512449748931382 0.60927138874913 LPGAT1 1 GO:0071108 protein K48-linked deubiquitination 1/380 35/18722 0.512449748931382 0.60927138874913 USP15 1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 1/380 35/18722 0.512449748931382 0.60927138874913 PTGS2 1 GO:0097421 liver regeneration 1/380 35/18722 0.512449748931382 0.60927138874913 CEBPB 1 GO:0098801 regulation of renal system process 1/380 35/18722 0.512449748931382 0.60927138874913 CYBA 1 GO:0106056 regulation of calcineurin-mediated signaling 1/380 35/18722 0.512449748931382 0.60927138874913 CLEC7A 1 GO:1905207 regulation of cardiocyte differentiation 1/380 35/18722 0.512449748931382 0.60927138874913 ARRB2 1 GO:1905898 positive regulation of response to endoplasmic reticulum stress 1/380 35/18722 0.512449748931382 0.60927138874913 NFE2L2 1 GO:0098727 maintenance of cell number 3/380 134/18722 0.513629983053722 0.610503221507862 SPI1/ZFP36L2/STAT3 3 GO:0044262 cellular carbohydrate metabolic process 6/380 283/18722 0.514587171132106 0.611469323721793 MGAM/PLEK/PYGL/MIDN/PTEN/STAT3 6 GO:0007051 spindle organization 4/380 184/18722 0.515355256813253 0.612210241964692 STAG2/HSPA1A/MYH9/VPS4B 4 GO:0060560 developmental growth involved in morphogenesis 5/380 234/18722 0.516771085171781 0.613532029797873 IQGAP1/CXCR4/TGFBR2/NIN/PAK1 5 GO:0006644 phospholipid metabolic process 8/380 383/18722 0.517300247162495 0.613532029797873 PLEK/MBOAT7/PTEN/LPGAT1/FAM126B/LPCAT2/OSBPL8/PLSCR1 8 GO:0009142 nucleoside triphosphate biosynthetic process 2/380 85/18722 0.517337161371477 0.613532029797873 TMSB4X/STAT3 2 GO:0055013 cardiac muscle cell development 2/380 85/18722 0.517337161371477 0.613532029797873 RGS2/PAK1 2 GO:0060021 roof of mouth development 2/380 85/18722 0.517337161371477 0.613532029797873 MMP25/TGFBR2 2 GO:0072384 organelle transport along microtubule 2/380 85/18722 0.517337161371477 0.613532029797873 AGTPBP1/HIF1A 2 GO:0015850 organic hydroxy compound transport 6/380 284/18722 0.518027391990951 0.614178612844815 AQP9/ACTB/TSPO/OSBPL8/SLC16A3/VPS4B 6 GO:0140013 meiotic nuclear division 4/380 185/18722 0.519613869511006 0.615887136126255 ACTR2/PRKAR1A/ACTR3/UBE2B 4 GO:0003203 endocardial cushion morphogenesis 1/380 36/18722 0.522364079503762 0.616215007436889 TGFBR2 1 GO:0007031 peroxisome organization 1/380 36/18722 0.522364079503762 0.616215007436889 RAB8B 1 GO:0010762 regulation of fibroblast migration 1/380 36/18722 0.522364079503762 0.616215007436889 PAK1 1 GO:0017004 cytochrome complex assembly 1/380 36/18722 0.522364079503762 0.616215007436889 CYBA 1 GO:0036314 response to sterol 1/380 36/18722 0.522364079503762 0.616215007436889 TGFBR2 1 GO:0038179 neurotrophin signaling pathway 1/380 36/18722 0.522364079503762 0.616215007436889 CORO1A 1 GO:0042092 type 2 immune response 1/380 36/18722 0.522364079503762 0.616215007436889 BCL6 1 GO:0042755 eating behavior 1/380 36/18722 0.522364079503762 0.616215007436889 STAT3 1 GO:0044060 regulation of endocrine process 1/380 36/18722 0.522364079503762 0.616215007436889 RAB8B 1 GO:0045738 negative regulation of DNA repair 1/380 36/18722 0.522364079503762 0.616215007436889 SMCHD1 1 GO:0045746 negative regulation of Notch signaling pathway 1/380 36/18722 0.522364079503762 0.616215007436889 BCL6 1 GO:0051354 negative regulation of oxidoreductase activity 1/380 36/18722 0.522364079503762 0.616215007436889 LRRK2 1 GO:0051955 regulation of amino acid transport 1/380 36/18722 0.522364079503762 0.616215007436889 RGS2 1 GO:0070306 lens fiber cell differentiation 1/380 36/18722 0.522364079503762 0.616215007436889 VIM 1 GO:0070897 transcription preinitiation complex assembly 1/380 36/18722 0.522364079503762 0.616215007436889 TAF7 1 GO:0097009 energy homeostasis 1/380 36/18722 0.522364079503762 0.616215007436889 STAT3 1 GO:1903539 protein localization to postsynaptic membrane 1/380 36/18722 0.522364079503762 0.616215007436889 STX3 1 GO:0014031 mesenchymal cell development 2/380 86/18722 0.523607914510916 0.61699485752747 HIF1A/MAPK1 2 GO:0015908 fatty acid transport 2/380 86/18722 0.523607914510916 0.61699485752747 ACSL1/IL1B 2 GO:1903510 mucopolysaccharide metabolic process 2/380 86/18722 0.523607914510916 0.61699485752747 IL1B/CD44 2 GO:2001251 negative regulation of chromosome organization 2/380 86/18722 0.523607914510916 0.61699485752747 DUSP1/NBN 2 GO:0033044 regulation of chromosome organization 4/380 187/18722 0.52807796590807 0.622089064150397 DUSP1/CUL3/MAPK1/NBN 4 GO:0034754 cellular hormone metabolic process 3/380 137/18722 0.528525572014248 0.62209721997786 TSPO/EGR1/HSD17B11 3 GO:0055123 digestive system development 3/380 137/18722 0.528525572014248 0.62209721997786 CXCL8/TGFBR2/HIF1A 3 GO:0090090 negative regulation of canonical Wnt signaling pathway 3/380 137/18722 0.528525572014248 0.62209721997786 STK4/EGR1/TLE3 3 GO:0007029 endoplasmic reticulum organization 2/380 87/18722 0.529823753134774 0.623451957356423 LRRK2/RTN3 2 GO:0003016 respiratory system process 1/380 37/18722 0.532077322026965 0.623505107577254 YWHAZ 1 GO:0003176 aortic valve development 1/380 37/18722 0.532077322026965 0.623505107577254 TNFRSF1B 1 GO:0014904 myotube cell development 1/380 37/18722 0.532077322026965 0.623505107577254 PPP3CA 1 GO:0033120 positive regulation of RNA splicing 1/380 37/18722 0.532077322026965 0.623505107577254 HSPA1A 1 GO:0033260 nuclear DNA replication 1/380 37/18722 0.532077322026965 0.623505107577254 BCL6 1 GO:0042178 xenobiotic catabolic process 1/380 37/18722 0.532077322026965 0.623505107577254 ACSL1 1 GO:0043687 post-translational protein modification 1/380 37/18722 0.532077322026965 0.623505107577254 AGTPBP1 1 GO:0050775 positive regulation of dendrite morphogenesis 1/380 37/18722 0.532077322026965 0.623505107577254 ACTR2 1 GO:0060428 lung epithelium development 1/380 37/18722 0.532077322026965 0.623505107577254 KLF2 1 GO:0062237 protein localization to postsynapse 1/380 37/18722 0.532077322026965 0.623505107577254 STX3 1 GO:0071542 dopaminergic neuron differentiation 1/380 37/18722 0.532077322026965 0.623505107577254 HIF1A 1 GO:0097484 dendrite extension 1/380 37/18722 0.532077322026965 0.623505107577254 CXCR4 1 GO:1900016 negative regulation of cytokine production involved in inflammatory response 1/380 37/18722 0.532077322026965 0.623505107577254 PYCARD 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/380 37/18722 0.532077322026965 0.623505107577254 MAPK1 1 GO:1905332 positive regulation of morphogenesis of an epithelium 1/380 37/18722 0.532077322026965 0.623505107577254 ITGAX 1 GO:0006575 cellular modified amino acid metabolic process 4/380 188/18722 0.532282845781935 0.623573403011478 VNN2/OSBPL8/PLSCR1/NFE2L2 4 GO:0006631 fatty acid metabolic process 8/380 390/18722 0.537898482777563 0.629977896726488 PTGS2/ACSL1/CYP4F3/ALOX5AP/ELOVL5/ALOX5/IL1B/LPGAT1 8 GO:0000578 embryonic axis specification 1/380 38/18722 0.541593544538592 0.631685117356358 BASP1 1 GO:0002385 mucosal immune response 1/380 38/18722 0.541593544538592 0.631685117356358 FFAR2 1 GO:0007094 mitotic spindle assembly checkpoint signaling 1/380 38/18722 0.541593544538592 0.631685117356358 DUSP1 1 GO:0008210 estrogen metabolic process 1/380 38/18722 0.541593544538592 0.631685117356358 HSD17B11 1 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/380 38/18722 0.541593544538592 0.631685117356358 PPP3CA 1 GO:0010719 negative regulation of epithelial to mesenchymal transition 1/380 38/18722 0.541593544538592 0.631685117356358 PTEN 1 GO:0032717 negative regulation of interleukin-8 production 1/380 38/18722 0.541593544538592 0.631685117356358 TMSB4X 1 GO:0032941 secretion by tissue 1/380 38/18722 0.541593544538592 0.631685117356358 CYBA 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/380 38/18722 0.541593544538592 0.631685117356358 SOD2 1 GO:0071173 spindle assembly checkpoint signaling 1/380 38/18722 0.541593544538592 0.631685117356358 DUSP1 1 GO:0071174 mitotic spindle checkpoint signaling 1/380 38/18722 0.541593544538592 0.631685117356358 DUSP1 1 GO:0071392 cellular response to estradiol stimulus 1/380 38/18722 0.541593544538592 0.631685117356358 CFLAR 1 GO:0071398 cellular response to fatty acid 1/380 38/18722 0.541593544538592 0.631685117356358 FFAR2 1 GO:0098926 postsynaptic signal transduction 1/380 38/18722 0.541593544538592 0.631685117356358 STAT3 1 GO:2000279 negative regulation of DNA biosynthetic process 1/380 38/18722 0.541593544538592 0.631685117356358 DUSP1 1 GO:0007292 female gamete generation 3/380 140/18722 0.54316482931229 0.633169020681956 PTGS2/RGS2/PRKAR1A 3 GO:0030177 positive regulation of Wnt signaling pathway 3/380 140/18722 0.54316482931229 0.633169020681956 LRRK2/UBE2B/DDX3X 3 GO:0006164 purine nucleotide biosynthetic process 4/380 191/18722 0.544785366490407 0.63488333161444 ACSL1/TMSB4X/ELOVL5/STAT3 4 GO:0032392 DNA geometric change 2/380 90/18722 0.548138375710306 0.638088515979424 DDX3X/NBN 2 GO:0035278 miRNA mediated inhibition of translation 2/380 90/18722 0.548138375710306 0.638088515979424 ZFP36/STAT3 2 GO:0040033 negative regulation of translation, ncRNA-mediated 2/380 90/18722 0.548138375710306 0.638088515979424 ZFP36/STAT3 2 GO:0046031 ADP metabolic process 2/380 90/18722 0.548138375710306 0.638088515979424 STAT3/HIF1A 2 GO:0010463 mesenchymal cell proliferation 1/380 39/18722 0.550916732992635 0.638864283741459 TGFBR2 1 GO:0014742 positive regulation of muscle hypertrophy 1/380 39/18722 0.550916732992635 0.638864283741459 PPP3CA 1 GO:0017158 regulation of calcium ion-dependent exocytosis 1/380 39/18722 0.550916732992635 0.638864283741459 STXBP3 1 GO:0021587 cerebellum morphogenesis 1/380 39/18722 0.550916732992635 0.638864283741459 AGTPBP1 1 GO:0031507 heterochromatin assembly 1/380 39/18722 0.550916732992635 0.638864283741459 SMCHD1 1 GO:0031577 spindle checkpoint signaling 1/380 39/18722 0.550916732992635 0.638864283741459 DUSP1 1 GO:0042417 dopamine metabolic process 1/380 39/18722 0.550916732992635 0.638864283741459 ITGB2 1 GO:0043267 negative regulation of potassium ion transport 1/380 39/18722 0.550916732992635 0.638864283741459 PTEN 1 GO:0045823 positive regulation of heart contraction 1/380 39/18722 0.550916732992635 0.638864283741459 RGS2 1 GO:0046461 neutral lipid catabolic process 1/380 39/18722 0.550916732992635 0.638864283741459 SORL1 1 GO:0046464 acylglycerol catabolic process 1/380 39/18722 0.550916732992635 0.638864283741459 SORL1 1 GO:0051084 'de novo' posttranslational protein folding 1/380 39/18722 0.550916732992635 0.638864283741459 HSPA1A 1 GO:0071548 response to dexamethasone 1/380 39/18722 0.550916732992635 0.638864283741459 CFLAR 1 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 1/380 39/18722 0.550916732992635 0.638864283741459 VMP1 1 GO:0001657 ureteric bud development 2/380 91/18722 0.554131330029334 0.641362717320096 BASP1/CAT 2 GO:0002065 columnar/cuboidal epithelial cell differentiation 2/380 91/18722 0.554131330029334 0.641362717320096 CEBPB/HIF1A 2 GO:0014033 neural crest cell differentiation 2/380 91/18722 0.554131330029334 0.641362717320096 HIF1A/MAPK1 2 GO:0042147 retrograde transport, endosome to Golgi 2/380 91/18722 0.554131330029334 0.641362717320096 LRRK2/RAB7A 2 GO:0045974 regulation of translation, ncRNA-mediated 2/380 91/18722 0.554131330029334 0.641362717320096 ZFP36/STAT3 2 GO:0055006 cardiac cell development 2/380 91/18722 0.554131330029334 0.641362717320096 RGS2/PAK1 2 GO:0060191 regulation of lipase activity 2/380 91/18722 0.554131330029334 0.641362717320096 RGS2/C5AR1 2 GO:0010876 lipid localization 9/380 448/18722 0.559718507783866 0.645236042541441 AQP9/ACSL1/FFAR2/IL1B/TSPO/OSBPL8/LRP10/PLSCR1/VPS4B 9 GO:0009394 2'-deoxyribonucleotide metabolic process 1/380 40/18722 0.560050792911427 0.645236042541441 TYMP 1 GO:0010863 positive regulation of phospholipase C activity 1/380 40/18722 0.560050792911427 0.645236042541441 C5AR1 1 GO:0014037 Schwann cell differentiation 1/380 40/18722 0.560050792911427 0.645236042541441 DICER1 1 GO:0030501 positive regulation of bone mineralization 1/380 40/18722 0.560050792911427 0.645236042541441 ALOX5 1 GO:0031297 replication fork processing 1/380 40/18722 0.560050792911427 0.645236042541441 BOD1L1 1 GO:0045777 positive regulation of blood pressure 1/380 40/18722 0.560050792911427 0.645236042541441 CYBA 1 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 1/380 40/18722 0.560050792911427 0.645236042541441 DUSP1 1 GO:0060412 ventricular septum morphogenesis 1/380 40/18722 0.560050792911427 0.645236042541441 TGFBR2 1 GO:0071526 semaphorin-plexin signaling pathway 1/380 40/18722 0.560050792911427 0.645236042541441 PLXNC1 1 GO:0072210 metanephric nephron development 1/380 40/18722 0.560050792911427 0.645236042541441 EGR1 1 GO:0097352 autophagosome maturation 1/380 40/18722 0.560050792911427 0.645236042541441 VMP1 1 GO:0006497 protein lipidation 2/380 92/18722 0.560067932085558 0.645236042541441 ZDHHC18/GLUL 2 GO:0032465 regulation of cytokinesis 2/380 92/18722 0.560067932085558 0.645236042541441 CUL3/SH3GLB1 2 GO:0072163 mesonephric epithelium development 2/380 92/18722 0.560067932085558 0.645236042541441 BASP1/CAT 2 GO:0072164 mesonephric tubule development 2/380 92/18722 0.560067932085558 0.645236042541441 BASP1/CAT 2 GO:1903312 negative regulation of mRNA metabolic process 2/380 92/18722 0.560067932085558 0.645236042541441 ZFP36/SLC11A1 2 GO:0006869 lipid transport 8/380 398/18722 0.561018822675089 0.646155755787055 AQP9/ACSL1/IL1B/TSPO/OSBPL8/LRP10/PLSCR1/VPS4B 8 GO:0001763 morphogenesis of a branching structure 4/380 196/18722 0.565233306210024 0.650832803643135 LRRK2/STK4/TGFBR2/PAK1 4 GO:0060349 bone morphogenesis 2/380 93/18722 0.565947995074579 0.650947789011636 ALPL/TGFBR2 2 GO:0060993 kidney morphogenesis 2/380 93/18722 0.565947995074579 0.650947789011636 LRRK2/BASP1 2 GO:1901796 regulation of signal transduction by p53 class mediator 2/380 93/18722 0.565947995074579 0.650947789011636 CD44/DDX5 2 GO:1902807 negative regulation of cell cycle G1/S phase transition 2/380 93/18722 0.565947995074579 0.650947789011636 CDKN2D/PTEN 2 GO:0007099 centriole replication 1/380 41/18722 0.56899955100444 0.653215803335268 VPS4B 1 GO:0044786 cell cycle DNA replication 1/380 41/18722 0.56899955100444 0.653215803335268 BCL6 1 GO:0050691 regulation of defense response to virus by host 1/380 41/18722 0.56899955100444 0.653215803335268 PYCARD 1 GO:0055023 positive regulation of cardiac muscle tissue growth 1/380 41/18722 0.56899955100444 0.653215803335268 MAPK1 1 GO:1902116 negative regulation of organelle assembly 1/380 41/18722 0.56899955100444 0.653215803335268 LRRK2 1 GO:1903524 positive regulation of blood circulation 1/380 41/18722 0.56899955100444 0.653215803335268 RGS2 1 GO:1905314 semi-lunar valve development 1/380 41/18722 0.56899955100444 0.653215803335268 TNFRSF1B 1 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 3/380 146/18722 0.571637877108145 0.655154686646727 ADGRE2/ADGRE5/GPR65 3 GO:0010675 regulation of cellular carbohydrate metabolic process 3/380 146/18722 0.571637877108145 0.655154686646727 PLEK/MIDN/STAT3 3 GO:0001738 morphogenesis of a polarized epithelium 2/380 94/18722 0.57177136289169 0.655154686646727 ACTB/MSN 2 GO:0014020 primary neural tube formation 2/380 94/18722 0.57177136289169 0.655154686646727 VASP/HIF1A 2 GO:0019080 viral gene expression 2/380 94/18722 0.57177136289169 0.655154686646727 ZFP36/IFITM3 2 GO:0051702 biological process involved in interaction with symbiont 2/380 94/18722 0.57177136289169 0.655154686646727 TREM1/IGF2R 2 GO:1903035 negative regulation of response to wounding 2/380 94/18722 0.57177136289169 0.655154686646727 ALOX5/PTEN 2 GO:0016331 morphogenesis of embryonic epithelium 3/380 147/18722 0.576275607347535 0.657753283563342 STK4/VASP/HIF1A 3 GO:1902850 microtubule cytoskeleton organization involved in mitosis 3/380 147/18722 0.576275607347535 0.657753283563342 STAG2/HSPA1A/VPS4B 3 GO:0008585 female gonad development 2/380 95/18722 0.577537908968847 0.657753283563342 CEBPB/ARRB2 2 GO:0008593 regulation of Notch signaling pathway 2/380 95/18722 0.577537908968847 0.657753283563342 BCL6/STAT3 2 GO:0000266 mitochondrial fission 1/380 42/18722 0.577766756754577 0.657753283563342 LRRK2 1 GO:0006040 amino sugar metabolic process 1/380 42/18722 0.577766756754577 0.657753283563342 CTBS 1 GO:0019692 deoxyribose phosphate metabolic process 1/380 42/18722 0.577766756754577 0.657753283563342 TYMP 1 GO:0021575 hindbrain morphogenesis 1/380 42/18722 0.577766756754577 0.657753283563342 AGTPBP1 1 GO:0021795 cerebral cortex cell migration 1/380 42/18722 0.577766756754577 0.657753283563342 MBOAT7 1 GO:0021879 forebrain neuron differentiation 1/380 42/18722 0.577766756754577 0.657753283563342 B2M 1 GO:0032467 positive regulation of cytokinesis 1/380 42/18722 0.577766756754577 0.657753283563342 CUL3 1 GO:0042168 heme metabolic process 1/380 42/18722 0.577766756754577 0.657753283563342 TSPO 1 GO:0043507 positive regulation of JUN kinase activity 1/380 42/18722 0.577766756754577 0.657753283563342 PAK1 1 GO:0045214 sarcomere organization 1/380 42/18722 0.577766756754577 0.657753283563342 PRKAR1A 1 GO:0045773 positive regulation of axon extension 1/380 42/18722 0.577766756754577 0.657753283563342 PAK1 1 GO:0046688 response to copper ion 1/380 42/18722 0.577766756754577 0.657753283563342 NFE2L2 1 GO:0060999 positive regulation of dendritic spine development 1/380 42/18722 0.577766756754577 0.657753283563342 ACTR2 1 GO:0071312 cellular response to alkaloid 1/380 42/18722 0.577766756754577 0.657753283563342 AIF1 1 GO:0072595 maintenance of protein localization in organelle 1/380 42/18722 0.577766756754577 0.657753283563342 TSPO 1 GO:0090317 negative regulation of intracellular protein transport 1/380 42/18722 0.577766756754577 0.657753283563342 LRRK2 1 GO:1900274 regulation of phospholipase C activity 1/380 42/18722 0.577766756754577 0.657753283563342 C5AR1 1 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 1/380 42/18722 0.577766756754577 0.657753283563342 DUSP1 1 GO:1904037 positive regulation of epithelial cell apoptotic process 1/380 42/18722 0.577766756754577 0.657753283563342 ARRB2 1 GO:2001222 regulation of neuron migration 1/380 42/18722 0.577766756754577 0.657753283563342 STAT3 1 GO:0006302 double-strand break repair 5/380 251/18722 0.579129857004111 0.659127907662566 SMCHD1/WAS/NABP1/ACTR2/NBN 5 GO:0044272 sulfur compound biosynthetic process 3/380 148/18722 0.580881880142736 0.660766790868785 ACSL1/ELOVL5/NFE2L2 3 GO:0050905 neuromuscular process 3/380 148/18722 0.580881880142736 0.660766790868785 PTEN/AGTPBP1/NBN 3 GO:0072522 purine-containing compound biosynthetic process 4/380 200/18722 0.581223860795866 0.660978262747179 ACSL1/TMSB4X/ELOVL5/STAT3 4 GO:0015849 organic acid transport 6/380 303/18722 0.581404726595796 0.661006447552535 RGS2/AQP9/ACSL1/SLC11A1/IL1B/SLC16A3 6 GO:0001823 mesonephros development 2/380 96/18722 0.583247535146013 0.662035194677933 BASP1/CAT 2 GO:0006637 acyl-CoA metabolic process 2/380 96/18722 0.583247535146013 0.662035194677933 ACSL1/ELOVL5 2 GO:0015914 phospholipid transport 2/380 96/18722 0.583247535146013 0.662035194677933 OSBPL8/PLSCR1 2 GO:0035383 thioester metabolic process 2/380 96/18722 0.583247535146013 0.662035194677933 ACSL1/ELOVL5 2 GO:0042158 lipoprotein biosynthetic process 2/380 96/18722 0.583247535146013 0.662035194677933 ZDHHC18/GLUL 2 GO:0044264 cellular polysaccharide metabolic process 2/380 96/18722 0.583247535146013 0.662035194677933 MGAM/PYGL 2 GO:0032368 regulation of lipid transport 3/380 149/18722 0.585456477427802 0.663252675113273 ACSL1/IL1B/TSPO 3 GO:0006458 'de novo' protein folding 1/380 43/18722 0.586356083972631 0.663252675113273 HSPA1A 1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 1/380 43/18722 0.586356083972631 0.663252675113273 SELL 1 GO:0033046 negative regulation of sister chromatid segregation 1/380 43/18722 0.586356083972631 0.663252675113273 DUSP1 1 GO:0033048 negative regulation of mitotic sister chromatid segregation 1/380 43/18722 0.586356083972631 0.663252675113273 DUSP1 1 GO:0034661 ncRNA catabolic process 1/380 43/18722 0.586356083972631 0.663252675113273 DICER1 1 GO:0042181 ketone biosynthetic process 1/380 43/18722 0.586356083972631 0.663252675113273 EGR1 1 GO:0045776 negative regulation of blood pressure 1/380 43/18722 0.586356083972631 0.663252675113273 SOD2 1 GO:0046636 negative regulation of alpha-beta T cell activation 1/380 43/18722 0.586356083972631 0.663252675113273 BCL6 1 GO:0046717 acid secretion 1/380 43/18722 0.586356083972631 0.663252675113273 SNX10 1 GO:0060443 mammary gland morphogenesis 1/380 43/18722 0.586356083972631 0.663252675113273 TGFBR2 1 GO:0140353 lipid export from cell 1/380 43/18722 0.586356083972631 0.663252675113273 IL1B 1 GO:2000816 negative regulation of mitotic sister chromatid separation 1/380 43/18722 0.586356083972631 0.663252675113273 DUSP1 1 GO:0000819 sister chromatid segregation 4/380 202/18722 0.589091892980061 0.666169336921377 DUSP1/STAG2/CUL3/VPS4B 4 GO:0043473 pigmentation 2/380 98/18722 0.594495770661438 0.669018790272894 LYST/RAB27A 2 GO:0006261 DNA-dependent DNA replication 3/380 151/18722 0.594509838804644 0.669018790272894 BCL6/BOD1L1/NBN 3 GO:0048592 eye morphogenesis 3/380 151/18722 0.594509838804644 0.669018790272894 AGTPBP1/STAT3/HIF1A 3 GO:0048754 branching morphogenesis of an epithelial tube 3/380 151/18722 0.594509838804644 0.669018790272894 STK4/TGFBR2/PAK1 3 GO:0002066 columnar/cuboidal epithelial cell development 1/380 44/18722 0.59477113232053 0.669018790272894 HIF1A 1 GO:0006775 fat-soluble vitamin metabolic process 1/380 44/18722 0.59477113232053 0.669018790272894 CYP4F3 1 GO:0007528 neuromuscular junction development 1/380 44/18722 0.59477113232053 0.669018790272894 LRRK2 1 GO:0008542 visual learning 1/380 44/18722 0.59477113232053 0.669018790272894 HIF1A 1 GO:0009262 deoxyribonucleotide metabolic process 1/380 44/18722 0.59477113232053 0.669018790272894 TYMP 1 GO:0030521 androgen receptor signaling pathway 1/380 44/18722 0.59477113232053 0.669018790272894 DDX5 1 GO:0032007 negative regulation of TOR signaling 1/380 44/18722 0.59477113232053 0.669018790272894 HIF1A 1 GO:0032620 interleukin-17 production 1/380 44/18722 0.59477113232053 0.669018790272894 OSM 1 GO:0032660 regulation of interleukin-17 production 1/380 44/18722 0.59477113232053 0.669018790272894 OSM 1 GO:0044058 regulation of digestive system process 1/380 44/18722 0.59477113232053 0.669018790272894 TYMP 1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 1/380 44/18722 0.59477113232053 0.669018790272894 MSN 1 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 1/380 44/18722 0.59477113232053 0.669018790272894 IL6R 1 GO:0048066 developmental pigmentation 1/380 44/18722 0.59477113232053 0.669018790272894 RAB27A 1 GO:0051150 regulation of smooth muscle cell differentiation 1/380 44/18722 0.59477113232053 0.669018790272894 SOD2 1 GO:0060324 face development 1/380 44/18722 0.59477113232053 0.669018790272894 MAPK1 1 GO:0089718 amino acid import across plasma membrane 1/380 44/18722 0.59477113232053 0.669018790272894 RGS2 1 GO:0090501 RNA phosphodiester bond hydrolysis 3/380 152/18722 0.59898823156271 0.673583420251747 RNASET2/DICER1/N4BP1 3 GO:0006165 nucleoside diphosphate phosphorylation 2/380 99/18722 0.600034316024535 0.674222692587929 STAT3/HIF1A 2 GO:0007631 feeding behavior 2/380 99/18722 0.600034316024535 0.674222692587929 FOS/STAT3 2 GO:0015837 amine transport 2/380 99/18722 0.600034316024535 0.674222692587929 RGS2/AQP9 2 GO:0003197 endocardial cushion development 1/380 45/18722 0.603015428803997 0.67488645374866 TGFBR2 1 GO:0006903 vesicle targeting 1/380 45/18722 0.603015428803997 0.67488645374866 CUL3 1 GO:0010824 regulation of centrosome duplication 1/380 45/18722 0.603015428803997 0.67488645374866 VPS4B 1 GO:0022602 ovulation cycle process 1/380 45/18722 0.603015428803997 0.67488645374866 ARRB2 1 GO:0030850 prostate gland development 1/380 45/18722 0.603015428803997 0.67488645374866 PTEN 1 GO:0031670 cellular response to nutrient 1/380 45/18722 0.603015428803997 0.67488645374866 NCOA1 1 GO:0032309 icosanoid secretion 1/380 45/18722 0.603015428803997 0.67488645374866 IL1B 1 GO:0035987 endodermal cell differentiation 1/380 45/18722 0.603015428803997 0.67488645374866 ITGB2 1 GO:0042551 neuron maturation 1/380 45/18722 0.603015428803997 0.67488645374866 LRRK2 1 GO:0048538 thymus development 1/380 45/18722 0.603015428803997 0.67488645374866 MAPK1 1 GO:0048546 digestive tract morphogenesis 1/380 45/18722 0.603015428803997 0.67488645374866 HIF1A 1 GO:0051180 vitamin transport 1/380 45/18722 0.603015428803997 0.67488645374866 SLC2A3 1 GO:0051985 negative regulation of chromosome segregation 1/380 45/18722 0.603015428803997 0.67488645374866 DUSP1 1 GO:0098534 centriole assembly 1/380 45/18722 0.603015428803997 0.67488645374866 VPS4B 1 GO:1905819 negative regulation of chromosome separation 1/380 45/18722 0.603015428803997 0.67488645374866 DUSP1 1 GO:0045165 cell fate commitment 5/380 258/18722 0.603536405162734 0.675264557300826 IL6R/MCL1/IFRD1/KDM6B/STAT3 5 GO:0032409 regulation of transporter activity 6/380 310/18722 0.603672163858543 0.675264557300826 CTSS/TMSB4X/ACTB/PTEN/VMP1/IFNGR2 6 GO:0006910 phagocytosis, recognition 2/380 100/18722 0.605515811506214 0.676969234880891 CLEC7A/FCN1 2 GO:0046545 development of primary female sexual characteristics 2/380 100/18722 0.605515811506214 0.676969234880891 CEBPB/ARRB2 2 GO:0070588 calcium ion transmembrane transport 6/380 312/18722 0.609915814681601 0.681225700924264 PTPRC/LYN/CORO1A/CYBA/VMP1/PTPN6 6 GO:0046939 nucleotide phosphorylation 2/380 101/18722 0.610940285196382 0.681225700924264 STAT3/HIF1A 2 GO:0006383 transcription by RNA polymerase III 1/380 46/18722 0.611092429235249 0.681225700924264 IVNS1ABP 1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 1/380 46/18722 0.611092429235249 0.681225700924264 JAML 1 GO:0031018 endocrine pancreas development 1/380 46/18722 0.611092429235249 0.681225700924264 IL6R 1 GO:0031648 protein destabilization 1/380 46/18722 0.611092429235249 0.681225700924264 CUL3 1 GO:0032924 activin receptor signaling pathway 1/380 46/18722 0.611092429235249 0.681225700924264 TGFBR2 1 GO:0033047 regulation of mitotic sister chromatid segregation 1/380 46/18722 0.611092429235249 0.681225700924264 DUSP1 1 GO:0046839 phospholipid dephosphorylation 1/380 46/18722 0.611092429235249 0.681225700924264 PTEN 1 GO:0048701 embryonic cranial skeleton morphogenesis 1/380 46/18722 0.611092429235249 0.681225700924264 TGFBR2 1 GO:0070828 heterochromatin organization 1/380 46/18722 0.611092429235249 0.681225700924264 SMCHD1 1 GO:0010970 transport along microtubule 3/380 155/18722 0.612228290003263 0.682312317937847 AGTPBP1/HIF1A/FLOT2 3 GO:0090305 nucleic acid phosphodiester bond hydrolysis 5/380 261/18722 0.613747472100966 0.683825452340855 ZFP36/RNASET2/PLSCR1/DICER1/N4BP1 5 GO:1904063 negative regulation of cation transmembrane transport 2/380 102/18722 0.616307787492986 0.686497496063333 RGS2/PTEN 2 GO:0006998 nuclear envelope organization 1/380 47/18722 0.619005519666315 0.687152916326827 PRKCB 1 GO:0010761 fibroblast migration 1/380 47/18722 0.619005519666315 0.687152916326827 PAK1 1 GO:0010799 regulation of peptidyl-threonine phosphorylation 1/380 47/18722 0.619005519666315 0.687152916326827 MAPK1 1 GO:0016574 histone ubiquitination 1/380 47/18722 0.619005519666315 0.687152916326827 UBE2B 1 GO:0032008 positive regulation of TOR signaling 1/380 47/18722 0.619005519666315 0.687152916326827 RICTOR 1 GO:0043114 regulation of vascular permeability 1/380 47/18722 0.619005519666315 0.687152916326827 CXCR2 1 GO:0045332 phospholipid translocation 1/380 47/18722 0.619005519666315 0.687152916326827 PLSCR1 1 GO:0045747 positive regulation of Notch signaling pathway 1/380 47/18722 0.619005519666315 0.687152916326827 STAT3 1 GO:0050885 neuromuscular process controlling balance 1/380 47/18722 0.619005519666315 0.687152916326827 NBN 1 GO:0051972 regulation of telomerase activity 1/380 47/18722 0.619005519666315 0.687152916326827 MAPK1 1 GO:0072583 clathrin-dependent endocytosis 1/380 47/18722 0.619005519666315 0.687152916326827 PICALM 1 GO:0101023 vascular endothelial cell proliferation 1/380 47/18722 0.619005519666315 0.687152916326827 STAT3 1 GO:1905562 regulation of vascular endothelial cell proliferation 1/380 47/18722 0.619005519666315 0.687152916326827 STAT3 1 GO:0009135 purine nucleoside diphosphate metabolic process 2/380 103/18722 0.621618390189571 0.689330684067252 STAT3/HIF1A 2 GO:0009179 purine ribonucleoside diphosphate metabolic process 2/380 103/18722 0.621618390189571 0.689330684067252 STAT3/HIF1A 2 GO:0030148 sphingolipid biosynthetic process 2/380 103/18722 0.621618390189571 0.689330684067252 ELOVL5/ST8SIA4 2 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 2/380 103/18722 0.621618390189571 0.689330684067252 PTPRC/IL6R 2 GO:0043414 macromolecule methylation 6/380 316/18722 0.622239343287736 0.689838643671089 SPI1/FOS/BTG2/BTG1/TET2/PCMTD1 6 GO:0002686 negative regulation of leukocyte migration 1/380 48/18722 0.626758017793587 0.693341265598314 DUSP1 1 GO:0015804 neutral amino acid transport 1/380 48/18722 0.626758017793587 0.693341265598314 RGS2 1 GO:0032527 protein exit from endoplasmic reticulum 1/380 48/18722 0.626758017793587 0.693341265598314 SORL1 1 GO:0044458 motile cilium assembly 1/380 48/18722 0.626758017793587 0.693341265598314 UBE2B 1 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 1/380 48/18722 0.626758017793587 0.693341265598314 BOD1L1 1 GO:0045839 negative regulation of mitotic nuclear division 1/380 48/18722 0.626758017793587 0.693341265598314 DUSP1 1 GO:0006892 post-Golgi vesicle-mediated transport 2/380 104/18722 0.626872185590541 0.693341265598314 SORL1/LAPTM5 2 GO:0022600 digestive system process 2/380 104/18722 0.626872185590541 0.693341265598314 SNX10/TYMP 2 GO:0032006 regulation of TOR signaling 2/380 104/18722 0.626872185590541 0.693341265598314 RICTOR/HIF1A 2 GO:0008202 steroid metabolic process 6/380 319/18722 0.63133554329609 0.698095568109384 TSPO/EGR1/HSD17B11/LBR/SF1/CAT 6 GO:0032412 regulation of ion transmembrane transporter activity 5/380 267/18722 0.633703509770304 0.699059509056757 CTSS/TMSB4X/PTEN/VMP1/IFNGR2 5 GO:0016042 lipid catabolic process 6/380 320/18722 0.634339221459706 0.699059509056757 SORL1/CYP4F3/HCAR2/IL1B/HSD17B11/RAB7A 6 GO:0006778 porphyrin-containing compound metabolic process 1/380 49/18722 0.634353174334148 0.699059509056757 TSPO 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/380 49/18722 0.634353174334148 0.699059509056757 SDCBP 1 GO:0021695 cerebellar cortex development 1/380 49/18722 0.634353174334148 0.699059509056757 AGTPBP1 1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1/380 49/18722 0.634353174334148 0.699059509056757 FBXL5 1 GO:0035088 establishment or maintenance of apical/basal cell polarity 1/380 49/18722 0.634353174334148 0.699059509056757 MSN 1 GO:0045778 positive regulation of ossification 1/380 49/18722 0.634353174334148 0.699059509056757 ALOX5 1 GO:0046605 regulation of centrosome cycle 1/380 49/18722 0.634353174334148 0.699059509056757 VPS4B 1 GO:0051932 synaptic transmission, GABAergic 1/380 49/18722 0.634353174334148 0.699059509056757 PTEN 1 GO:0061245 establishment or maintenance of bipolar cell polarity 1/380 49/18722 0.634353174334148 0.699059509056757 MSN 1 GO:1904894 positive regulation of receptor signaling pathway via STAT 1/380 49/18722 0.634353174334148 0.699059509056757 IL6R 1 GO:1990573 potassium ion import across plasma membrane 1/380 49/18722 0.634353174334148 0.699059509056757 KCNJ15 1 GO:0006090 pyruvate metabolic process 2/380 106/18722 0.637209821156851 0.701659800467827 STAT3/HIF1A 2 GO:0007218 neuropeptide signaling pathway 2/380 106/18722 0.637209821156851 0.701659800467827 PROK2/SORL1 2 GO:0009185 ribonucleoside diphosphate metabolic process 2/380 106/18722 0.637209821156851 0.701659800467827 STAT3/HIF1A 2 GO:0006220 pyrimidine nucleotide metabolic process 1/380 50/18722 0.641794174374475 0.705423910842435 TYMP 1 GO:0007632 visual behavior 1/380 50/18722 0.641794174374475 0.705423910842435 HIF1A 1 GO:0008089 anterograde axonal transport 1/380 50/18722 0.641794174374475 0.705423910842435 AGTPBP1 1 GO:0018023 peptidyl-lysine trimethylation 1/380 50/18722 0.641794174374475 0.705423910842435 TET2 1 GO:0060688 regulation of morphogenesis of a branching structure 1/380 50/18722 0.641794174374475 0.705423910842435 LRRK2 1 GO:1902930 regulation of alcohol biosynthetic process 1/380 50/18722 0.641794174374475 0.705423910842435 PLEK 1 GO:2000677 regulation of transcription regulatory region DNA binding 1/380 50/18722 0.641794174374475 0.705423910842435 TMSB4X 1 GO:0005976 polysaccharide metabolic process 2/380 107/18722 0.642293940895316 0.705790046624718 MGAM/PYGL 2 GO:0009948 anterior/posterior axis specification 1/380 51/18722 0.649084138692047 0.711958385744838 BASP1 1 GO:0021872 forebrain generation of neurons 1/380 51/18722 0.649084138692047 0.711958385744838 B2M 1 GO:0032873 negative regulation of stress-activated MAPK cascade 1/380 51/18722 0.649084138692047 0.711958385744838 DUSP1 1 GO:0045104 intermediate filament cytoskeleton organization 1/380 51/18722 0.649084138692047 0.711958385744838 VIM 1 GO:0050982 detection of mechanical stimulus 1/380 51/18722 0.649084138692047 0.711958385744838 CXCR4 1 GO:0051293 establishment of spindle localization 1/380 51/18722 0.649084138692047 0.711958385744838 MYH9 1 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 1/380 51/18722 0.649084138692047 0.711958385744838 DUSP1 1 GO:0050680 negative regulation of epithelial cell proliferation 3/380 164/18722 0.650164142871036 0.712958349316116 B2M/ALOX5/PTEN 3 GO:0034766 negative regulation of ion transmembrane transport 2/380 109/18722 0.652293613667347 0.715108323551958 RGS2/PTEN 2 GO:0046942 carboxylic acid transport 5/380 273/18722 0.653019604096923 0.71571895014246 RGS2/AQP9/SLC11A1/IL1B/SLC16A3 5 GO:0022618 ribonucleoprotein complex assembly 4/380 220/18722 0.655857795971612 0.71793274078752 CELF2/DICER1/ADAR/SF1 4 GO:0007129 homologous chromosome pairing at meiosis 1/380 52/18722 0.656226125050411 0.71793274078752 UBE2B 1 GO:0034204 lipid translocation 1/380 52/18722 0.656226125050411 0.71793274078752 PLSCR1 1 GO:0035176 social behavior 1/380 52/18722 0.656226125050411 0.71793274078752 PTEN 1 GO:0043090 amino acid import 1/380 52/18722 0.656226125050411 0.71793274078752 RGS2 1 GO:0045103 intermediate filament-based process 1/380 52/18722 0.656226125050411 0.71793274078752 VIM 1 GO:0072132 mesenchyme morphogenesis 1/380 52/18722 0.656226125050411 0.71793274078752 TGFBR2 1 GO:0003014 renal system process 2/380 110/18722 0.6572095474548 0.718637344041074 CYBA/HBB 2 GO:1905954 positive regulation of lipid localization 2/380 110/18722 0.6572095474548 0.718637344041074 ACSL1/IL1B 2 GO:0042391 regulation of membrane potential 8/380 434/18722 0.658101774376991 0.719427210760598 SOD2/LRRK2/ARRB2/TSPO/PTEN/BNIP3L/BID/PPP3CA 8 GO:0006805 xenobiotic metabolic process 2/380 111/18722 0.662069825540581 0.723578248042415 S100A12/ACSL1 2 GO:0016925 protein sumoylation 1/380 53/18722 0.663223129468239 0.723904627138658 EGR1 1 GO:0032210 regulation of telomere maintenance via telomerase 1/380 53/18722 0.663223129468239 0.723904627138658 MAPK1 1 GO:0043113 receptor clustering 1/380 53/18722 0.663223129468239 0.723904627138658 ITGB2 1 GO:0051438 regulation of ubiquitin-protein transferase activity 1/380 53/18722 0.663223129468239 0.723904627138658 PTEN 1 GO:0071715 icosanoid transport 1/380 53/18722 0.663223129468239 0.723904627138658 IL1B 1 GO:0000070 mitotic sister chromatid segregation 3/380 168/18722 0.666154912380727 0.726917303254929 DUSP1/CUL3/VPS4B 3 GO:0000075 cell cycle checkpoint signaling 3/380 169/18722 0.670068588159751 0.730069642502013 DUSP1/NABP1/NBN 3 GO:0006584 catecholamine metabolic process 1/380 54/18722 0.670078087462886 0.730069642502013 ITGB2 1 GO:0007215 glutamate receptor signaling pathway 1/380 54/18722 0.670078087462886 0.730069642502013 CPEB4 1 GO:0009712 catechol-containing compound metabolic process 1/380 54/18722 0.670078087462886 0.730069642502013 ITGB2 1 GO:0051703 biological process involved in intraspecies interaction between organisms 1/380 54/18722 0.670078087462886 0.730069642502013 PTEN 1 GO:0070839 metal ion export 1/380 54/18722 0.670078087462886 0.730069642502013 SLC11A1 1 GO:0019751 polyol metabolic process 2/380 114/18722 0.676319069579407 0.735872159631353 PLEK/PTEN 2 GO:0046660 female sex differentiation 2/380 114/18722 0.676319069579407 0.735872159631353 CEBPB/ARRB2 2 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/380 114/18722 0.676319069579407 0.735872159631353 LRG1/SDCBP 2 GO:1904892 regulation of receptor signaling pathway via STAT 2/380 114/18722 0.676319069579407 0.735872159631353 PTPRC/IL6R 2 GO:0001755 neural crest cell migration 1/380 55/18722 0.676793875268977 0.735872159631353 HIF1A 1 GO:0003179 heart valve morphogenesis 1/380 55/18722 0.676793875268977 0.735872159631353 TGFBR2 1 GO:0006414 translational elongation 1/380 55/18722 0.676793875268977 0.735872159631353 ABTB1 1 GO:0046164 alcohol catabolic process 1/380 55/18722 0.676793875268977 0.735872159631353 PTEN 1 GO:0007411 axon guidance 4/380 227/18722 0.679769859588484 0.738728600296954 PLXNC1/RAC2/VASP/RHOG 4 GO:0071826 ribonucleoprotein complex subunit organization 4/380 227/18722 0.679769859588484 0.738728600296954 CELF2/DICER1/ADAR/SF1 4 GO:0043279 response to alkaloid 2/380 115/18722 0.680959134672552 0.739641429940563 AIF1/CXCR4 2 GO:0090630 activation of GTPase activity 2/380 115/18722 0.680959134672552 0.739641429940563 GPR65/RHOG 2 GO:0007219 Notch signaling pathway 3/380 172/18722 0.681608025212778 0.739966671821614 BCL6/STAT3/TGFBR2 3 GO:1990138 neuron projection extension 3/380 172/18722 0.681608025212778 0.739966671821614 IQGAP1/CXCR4/PAK1 3 GO:0097485 neuron projection guidance 4/380 228/18722 0.683089715532523 0.740933428628434 PLXNC1/RAC2/VASP/RHOG 4 GO:0006687 glycosphingolipid metabolic process 1/380 56/18722 0.683373311032506 0.740933428628434 ST8SIA4 1 GO:0010518 positive regulation of phospholipase activity 1/380 56/18722 0.683373311032506 0.740933428628434 C5AR1 1 GO:0043388 positive regulation of DNA binding 1/380 56/18722 0.683373311032506 0.740933428628434 PLAUR 1 GO:0045599 negative regulation of fat cell differentiation 1/380 56/18722 0.683373311032506 0.740933428628434 ZFP36L2 1 GO:0045333 cellular respiration 4/380 230/18722 0.689657015914526 0.746775083225798 BID/HIF1A/IFNAR1/CAT 4 GO:0006695 cholesterol biosynthetic process 1/380 57/18722 0.689819155980949 0.746775083225798 LBR 1 GO:0010883 regulation of lipid storage 1/380 57/18722 0.689819155980949 0.746775083225798 OSBPL8 1 GO:0030219 megakaryocyte differentiation 1/380 57/18722 0.689819155980949 0.746775083225798 PTPN6 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/380 57/18722 0.689819155980949 0.746775083225798 ARRB2 1 GO:1902653 secondary alcohol biosynthetic process 1/380 57/18722 0.689819155980949 0.746775083225798 LBR 1 GO:0030301 cholesterol transport 2/380 117/18722 0.690076393127911 0.746862643725199 TSPO/VPS4B 2 GO:0050954 sensory perception of mechanical stimulus 3/380 175/18722 0.692845599232522 0.749668143267687 CDKN2D/MBP/CXCR4 3 GO:0001954 positive regulation of cell-matrix adhesion 1/380 58/18722 0.696134115569872 0.751689948862419 IQGAP1 1 GO:0007131 reciprocal meiotic recombination 1/380 58/18722 0.696134115569872 0.751689948862419 UBE2B 1 GO:0010559 regulation of glycoprotein biosynthetic process 1/380 58/18722 0.696134115569872 0.751689948862419 ITM2B 1 GO:0018208 peptidyl-proline modification 1/380 58/18722 0.696134115569872 0.751689948862419 EGLN1 1 GO:0032387 negative regulation of intracellular transport 1/380 58/18722 0.696134115569872 0.751689948862419 LRRK2 1 GO:0043506 regulation of JUN kinase activity 1/380 58/18722 0.696134115569872 0.751689948862419 PAK1 1 GO:0097035 regulation of membrane lipid distribution 1/380 58/18722 0.696134115569872 0.751689948862419 PLSCR1 1 GO:0140527 reciprocal homologous recombination 1/380 58/18722 0.696134115569872 0.751689948862419 UBE2B 1 GO:0019693 ribose phosphate metabolic process 7/380 396/18722 0.696357270175391 0.751739240171496 LRRK2/ACSL1/TMSB4X/PYGL/ELOVL5/STAT3/HIF1A 7 GO:0033013 tetrapyrrole metabolic process 1/380 59/18722 0.70232084060649 0.757404828105039 TSPO 1 GO:0051568 histone H3-K4 methylation 1/380 59/18722 0.70232084060649 0.757404828105039 TET2 1 GO:0071806 protein transmembrane transport 1/380 59/18722 0.70232084060649 0.757404828105039 MCL1 1 GO:2000351 regulation of endothelial cell apoptotic process 1/380 59/18722 0.70232084060649 0.757404828105039 NFE2L2 1 GO:0003206 cardiac chamber morphogenesis 2/380 121/18722 0.707667897457423 0.762969854162021 TGFBR2/HIF1A 2 GO:0006081 cellular aldehyde metabolic process 1/380 60/18722 0.708381928350665 0.762969854162021 TALDO1 1 GO:0035825 homologous recombination 1/380 60/18722 0.708381928350665 0.762969854162021 UBE2B 1 GO:0051851 modulation by host of symbiont process 1/380 60/18722 0.708381928350665 0.762969854162021 IGF2R 1 GO:0061951 establishment of protein localization to plasma membrane 1/380 60/18722 0.708381928350665 0.762969854162021 RAB7A 1 GO:0015698 inorganic anion transport 3/380 180/18722 0.710907502570356 0.765495365722211 SLC11A1/CEBPB/TSPO 3 GO:0019748 secondary metabolic process 1/380 61/18722 0.714319923593766 0.767803268126802 NFE2L2 1 GO:0040014 regulation of multicellular organism growth 1/380 61/18722 0.714319923593766 0.767803268126802 STAT3 1 GO:0042255 ribosome assembly 1/380 61/18722 0.714319923593766 0.767803268126802 DDX3X 1 GO:0043954 cellular component maintenance 1/380 61/18722 0.714319923593766 0.767803268126802 CD177 1 GO:0043966 histone H3 acetylation 1/380 61/18722 0.714319923593766 0.767803268126802 SPI1 1 GO:1904356 regulation of telomere maintenance via telomere lengthening 1/380 61/18722 0.714319923593766 0.767803268126802 MAPK1 1 GO:1905515 non-motile cilium assembly 1/380 61/18722 0.714319923593766 0.767803268126802 CEP350 1 GO:0003231 cardiac ventricle development 2/380 123/18722 0.716147330727891 0.769572176004217 TGFBR2/HIF1A 2 GO:0061138 morphogenesis of a branching epithelium 3/380 182/18722 0.717900274589134 0.771260188453826 STK4/TGFBR2/PAK1 3 GO:0007062 sister chromatid cohesion 1/380 62/18722 0.720137319715858 0.772280844146698 STAG2 1 GO:0007588 excretion 1/380 62/18722 0.720137319715858 0.772280844146698 AQP9 1 GO:0031124 mRNA 3'-end processing 1/380 62/18722 0.720137319715858 0.772280844146698 ZFP36L1 1 GO:0046148 pigment biosynthetic process 1/380 62/18722 0.720137319715858 0.772280844146698 TSPO 1 GO:0046173 polyol biosynthetic process 1/380 62/18722 0.720137319715858 0.772280844146698 PLEK 1 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1/380 62/18722 0.720137319715858 0.772280844146698 SDCBP 1 GO:0007368 determination of left/right symmetry 2/380 124/18722 0.720309169865279 0.772280844146698 TGFBR2/HIF1A 2 GO:0009132 nucleoside diphosphate metabolic process 2/380 124/18722 0.720309169865279 0.772280844146698 STAT3/HIF1A 2 GO:0048193 Golgi vesicle transport 5/380 296/18722 0.720877181844406 0.772677056617215 SORL1/LRRK2/LAPTM5/RAB8B/CUL3 5 GO:0032886 regulation of microtubule-based process 4/380 240/18722 0.721043619303715 0.772677056617215 NIN/HSPA1A/VPS4B/PAK1 4 GO:2001257 regulation of cation channel activity 3/380 184/18722 0.724761522571699 0.776464722512306 CTSS/TMSB4X/IFNGR2 3 GO:0045143 homologous chromosome segregation 1/380 63/18722 0.725836559721645 0.777223218816983 UBE2B 1 GO:0099601 regulation of neurotransmitter receptor activity 1/380 63/18722 0.725836559721645 0.777223218816983 IFNGR2 1 GO:0015711 organic anion transport 6/380 354/18722 0.727533245971274 0.778683610836031 RGS2/AQP9/SLC2A3/SLC11A1/IL1B/SLC16A3 6 GO:0006325 chromatin organization 7/380 409/18722 0.727568134138884 0.778683610836031 ACTB/SMCHD1/KDM6B/KDM5A/BAZ2B/PAK1/UBN1 7 GO:0031929 TOR signaling 2/380 126/18722 0.728478895303677 0.779461374838573 RICTOR/HIF1A 2 GO:0006749 glutathione metabolic process 1/380 64/18722 0.731420037255584 0.780636052867288 NFE2L2 1 GO:0016126 sterol biosynthetic process 1/380 64/18722 0.731420037255584 0.780636052867288 LBR 1 GO:0030104 water homeostasis 1/380 64/18722 0.731420037255584 0.780636052867288 AQP9 1 GO:0030858 positive regulation of epithelial cell differentiation 1/380 64/18722 0.731420037255584 0.780636052867288 BTG1 1 GO:0045995 regulation of embryonic development 1/380 64/18722 0.731420037255584 0.780636052867288 NFE2L2 1 GO:0046579 positive regulation of Ras protein signal transduction 1/380 64/18722 0.731420037255584 0.780636052867288 GPR65 1 GO:0046854 phosphatidylinositol phosphate biosynthetic process 1/380 64/18722 0.731420037255584 0.780636052867288 FAM126B 1 GO:0048247 lymphocyte chemotaxis 1/380 64/18722 0.731420037255584 0.780636052867288 CKLF 1 GO:0050771 negative regulation of axonogenesis 1/380 64/18722 0.731420037255584 0.780636052867288 PTEN 1 GO:1903018 regulation of glycoprotein metabolic process 1/380 64/18722 0.731420037255584 0.780636052867288 ITM2B 1 GO:0030198 extracellular matrix organization 5/380 301/18722 0.734304290577384 0.783516923808319 LCP1/MMP25/CTSS/CFLAR/TNFRSF1B 5 GO:0033865 nucleoside bisphosphate metabolic process 2/380 128/18722 0.736445829719789 0.7839513386258 ACSL1/ELOVL5 2 GO:0033875 ribonucleoside bisphosphate metabolic process 2/380 128/18722 0.736445829719789 0.7839513386258 ACSL1/ELOVL5 2 GO:0034032 purine nucleoside bisphosphate metabolic process 2/380 128/18722 0.736445829719789 0.7839513386258 ACSL1/ELOVL5 2 GO:0015909 long-chain fatty acid transport 1/380 65/18722 0.736890097596611 0.7839513386258 ACSL1 1 GO:0035418 protein localization to synapse 1/380 65/18722 0.736890097596611 0.7839513386258 STX3 1 GO:0046503 glycerolipid catabolic process 1/380 65/18722 0.736890097596611 0.7839513386258 SORL1 1 GO:0046513 ceramide biosynthetic process 1/380 65/18722 0.736890097596611 0.7839513386258 ST8SIA4 1 GO:0061512 protein localization to cilium 1/380 65/18722 0.736890097596611 0.7839513386258 SNX10 1 GO:0072577 endothelial cell apoptotic process 1/380 65/18722 0.736890097596611 0.7839513386258 NFE2L2 1 GO:1902475 L-alpha-amino acid transmembrane transport 1/380 65/18722 0.736890097596611 0.7839513386258 RGS2 1 GO:1905330 regulation of morphogenesis of an epithelium 1/380 65/18722 0.736890097596611 0.7839513386258 ITGAX 1 GO:0043062 extracellular structure organization 5/380 302/18722 0.736932769555917 0.7839513386258 LCP1/MMP25/CTSS/CFLAR/TNFRSF1B 5 GO:0009060 aerobic respiration 3/380 189/18722 0.741344792970022 0.788220832148987 BID/HIF1A/CAT 3 GO:0045229 external encapsulating structure organization 5/380 304/18722 0.742132902249732 0.788220832148987 LCP1/MMP25/CTSS/CFLAR/TNFRSF1B 5 GO:0006303 double-strand break repair via nonhomologous end joining 1/380 66/18722 0.74224903863286 0.788220832148987 SMCHD1 1 GO:0030193 regulation of blood coagulation 1/380 66/18722 0.74224903863286 0.788220832148987 NFE2L2 1 GO:0071300 cellular response to retinoic acid 1/380 66/18722 0.74224903863286 0.788220832148987 LYN 1 GO:1905953 negative regulation of lipid localization 1/380 66/18722 0.74224903863286 0.788220832148987 OSBPL8 1 GO:2000272 negative regulation of signaling receptor activity 1/380 66/18722 0.74224903863286 0.788220832148987 PTEN 1 GO:0007098 centrosome cycle 2/380 130/18722 0.744213029997471 0.790085576008729 NIN/VPS4B 2 GO:0051216 cartilage development 3/380 190/18722 0.74456470693054 0.790085576008729 CD44/TGFBR2/HIF1A 3 GO:0099111 microtubule-based transport 3/380 190/18722 0.74456470693054 0.790085576008729 AGTPBP1/HIF1A/FLOT2 3 GO:0009880 embryonic pattern specification 1/380 67/18722 0.747499111816796 0.792802088290541 BASP1 1 GO:0061077 chaperone-mediated protein folding 1/380 67/18722 0.747499111816796 0.792802088290541 HSPA1A 1 GO:0000723 telomere maintenance 2/380 131/18722 0.748022707905525 0.793158780165222 MAPK1/NBN 2 GO:0032259 methylation 6/380 364/18722 0.751524364318956 0.796263074027821 SPI1/FOS/BTG2/BTG1/TET2/PCMTD1 6 GO:0009247 glycolipid biosynthetic process 1/380 68/18722 0.752642523101149 0.796263074027821 ST8SIA4 1 GO:0009988 cell-cell recognition 1/380 68/18722 0.752642523101149 0.796263074027821 MSN 1 GO:0060411 cardiac septum morphogenesis 1/380 68/18722 0.752642523101149 0.796263074027821 TGFBR2 1 GO:0061912 selective autophagy 1/380 68/18722 0.752642523101149 0.796263074027821 RAB7A 1 GO:1900046 regulation of hemostasis 1/380 68/18722 0.752642523101149 0.796263074027821 NFE2L2 1 GO:1901016 regulation of potassium ion transmembrane transporter activity 1/380 68/18722 0.752642523101149 0.796263074027821 PTEN 1 GO:1901607 alpha-amino acid biosynthetic process 1/380 68/18722 0.752642523101149 0.796263074027821 GLUL 1 GO:1904888 cranial skeletal system development 1/380 68/18722 0.752642523101149 0.796263074027821 TGFBR2 1 GO:0009855 determination of bilateral symmetry 2/380 133/18722 0.755496215268358 0.799082535379995 TGFBR2/HIF1A 2 GO:0007004 telomere maintenance via telomerase 1/380 69/18722 0.757681433856031 0.800194731266906 MAPK1 1 GO:0015807 L-amino acid transport 1/380 69/18722 0.757681433856031 0.800194731266906 SLC11A1 1 GO:0019226 transmission of nerve impulse 1/380 69/18722 0.757681433856031 0.800194731266906 TYMP 1 GO:0045665 negative regulation of neuron differentiation 1/380 69/18722 0.757681433856031 0.800194731266906 B2M 1 GO:0060193 positive regulation of lipase activity 1/380 69/18722 0.757681433856031 0.800194731266906 C5AR1 1 GO:0070192 chromosome organization involved in meiotic cell cycle 1/380 69/18722 0.757681433856031 0.800194731266906 UBE2B 1 GO:0009799 specification of symmetry 2/380 134/18722 0.759160855150398 0.801557272890037 TGFBR2/HIF1A 2 GO:0009150 purine ribonucleotide metabolic process 6/380 368/18722 0.76068161113195 0.802962767483501 LRRK2/ACSL1/TMSB4X/ELOVL5/STAT3/HIF1A 6 GO:0009581 detection of external stimulus 2/380 135/18722 0.762777965373406 0.804774460228295 ARRB2/CXCR4 2 GO:0042157 lipoprotein metabolic process 2/380 135/18722 0.762777965373406 0.804774460228295 ZDHHC18/GLUL 2 GO:0043547 positive regulation of GTPase activity 4/380 255/18722 0.76362945367958 0.805472163470241 PREX1/GPR65/PICALM/RHOG 4 GO:0090596 sensory organ morphogenesis 4/380 256/18722 0.766280001846913 0.807865523480627 AGTPBP1/STAT3/HIF1A/MAPK1 4 GO:1903522 regulation of blood circulation 4/380 256/18722 0.766280001846913 0.807865523480627 PTGS2/RGS2/CELF2/DOCK5 4 GO:0000281 mitotic cytokinesis 1/380 71/18722 0.767454181718732 0.808298547520227 VPS4B 1 GO:0003281 ventricular septum development 1/380 71/18722 0.767454181718732 0.808298547520227 TGFBR2 1 GO:0050795 regulation of behavior 1/380 71/18722 0.767454181718732 0.808298547520227 STAT3 1 GO:0050818 regulation of coagulation 1/380 71/18722 0.767454181718732 0.808298547520227 NFE2L2 1 GO:0007586 digestion 2/380 137/18722 0.769871254200925 0.810239751873985 SNX10/TYMP 2 GO:0008203 cholesterol metabolic process 2/380 137/18722 0.769871254200925 0.810239751873985 LBR/CAT 2 GO:0060048 cardiac muscle contraction 2/380 137/18722 0.769871254200925 0.810239751873985 RGS2/CXCR4 2 GO:0005977 glycogen metabolic process 1/380 72/18722 0.772192126651813 0.812278603171989 PYGL 1 GO:0035567 non-canonical Wnt signaling pathway 1/380 72/18722 0.772192126651813 0.812278603171989 RNF213 1 GO:0009582 detection of abiotic stimulus 2/380 138/18722 0.773348268266326 0.813292752944597 ARRB2/CXCR4 2 GO:0015980 energy derivation by oxidation of organic compounds 5/380 318/18722 0.776429632516056 0.815136544582507 PYGL/BID/HIF1A/IFNAR1/CAT 5 GO:0006260 DNA replication 4/380 260/18722 0.776651199578655 0.815136544582507 BCL6/S100A11/BOD1L1/NBN 4 GO:0016579 protein deubiquitination 2/380 139/18722 0.776779423036581 0.815136544582507 USP15/USP10 2 GO:0009166 nucleotide catabolic process 1/380 73/18722 0.776833788414403 0.815136544582507 TYMP 1 GO:0051145 smooth muscle cell differentiation 1/380 73/18722 0.776833788414403 0.815136544582507 SOD2 1 GO:0051298 centrosome duplication 1/380 73/18722 0.776833788414403 0.815136544582507 VPS4B 1 GO:0051937 catecholamine transport 1/380 73/18722 0.776833788414403 0.815136544582507 ACTB 1 GO:0099518 vesicle cytoskeletal trafficking 1/380 73/18722 0.776833788414403 0.815136544582507 MYO1F 1 GO:1904427 positive regulation of calcium ion transmembrane transport 1/380 73/18722 0.776833788414403 0.815136544582507 VMP1 1 GO:0044282 small molecule catabolic process 6/380 376/18722 0.778249034828819 0.816419287218243 CDA/CYP4F3/APOBEC3A/PTEN/GLUL/NQO2 6 GO:0015748 organophosphate ester transport 2/380 140/18722 0.780165141786209 0.818024108805297 OSBPL8/PLSCR1 2 GO:0046165 alcohol biosynthetic process 2/380 140/18722 0.780165141786209 0.818024108805297 PLEK/LBR 2 GO:0006024 glycosaminoglycan biosynthetic process 1/380 75/18722 0.785836029298627 0.823358630400714 IL1B 1 GO:0006278 RNA-dependent DNA biosynthetic process 1/380 75/18722 0.785836029298627 0.823358630400714 MAPK1 1 GO:0045913 positive regulation of carbohydrate metabolic process 1/380 75/18722 0.785836029298627 0.823358630400714 HIF1A 1 GO:1901888 regulation of cell junction assembly 3/380 204/18722 0.786356904577536 0.8237005913643 IL1B/PTEN/IQGAP1 3 GO:0046467 membrane lipid biosynthetic process 2/380 142/18722 0.786801972829749 0.823962995779918 ELOVL5/ST8SIA4 2 GO:0006865 amino acid transport 2/380 143/18722 0.790053939456086 0.82629596756879 RGS2/SLC11A1 2 GO:0031023 microtubule organizing center organization 2/380 143/18722 0.790053939456086 0.82629596756879 NIN/VPS4B 2 GO:0001937 negative regulation of endothelial cell proliferation 1/380 76/18722 0.790200394015017 0.82629596756879 ALOX5 1 GO:0008652 cellular amino acid biosynthetic process 1/380 76/18722 0.790200394015017 0.82629596756879 GLUL 1 GO:0009123 nucleoside monophosphate metabolic process 1/380 76/18722 0.790200394015017 0.82629596756879 TYMP 1 GO:0021536 diencephalon development 1/380 76/18722 0.790200394015017 0.82629596756879 NCOA1 1 GO:0007018 microtubule-based movement 6/380 382/18722 0.790777751372332 0.826695575675592 AGTPBP1/ACTR2/ACTR3/UBE2B/HIF1A/FLOT2 6 GO:0006367 transcription initiation from RNA polymerase II promoter 1/380 77/18722 0.794476048325555 0.829742556019415 TAF7 1 GO:0021675 nerve development 1/380 77/18722 0.794476048325555 0.829742556019415 DICER1 1 GO:0031016 pancreas development 1/380 77/18722 0.794476048325555 0.829742556019415 IL6R 1 GO:0055117 regulation of cardiac muscle contraction 1/380 77/18722 0.794476048325555 0.829742556019415 RGS2 1 GO:0009259 ribonucleotide metabolic process 6/380 385/18722 0.796836807245278 0.832002928669564 LRRK2/ACSL1/TMSB4X/ELOVL5/STAT3/HIF1A 6 GO:0009064 glutamine family amino acid metabolic process 1/380 78/18722 0.798664790703474 0.833089997199313 GLUL 1 GO:0032371 regulation of sterol transport 1/380 78/18722 0.798664790703474 0.833089997199313 TSPO 1 GO:0032374 regulation of cholesterol transport 1/380 78/18722 0.798664790703474 0.833089997199313 TSPO 1 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 1/380 78/18722 0.798664790703474 0.833089997199313 PTGS2 1 GO:0060041 retina development in camera-type eye 2/380 147/18722 0.802628827376248 0.836752178952839 AGTPBP1/HIF1A 2 GO:1902652 secondary alcohol metabolic process 2/380 147/18722 0.802628827376248 0.836752178952839 LBR/CAT 2 GO:0006023 aminoglycan biosynthetic process 1/380 79/18722 0.802768383255108 0.836752178952839 IL1B 1 GO:0007422 peripheral nervous system development 1/380 80/18722 0.806788552453363 0.840528787119309 DICER1 1 GO:0009791 post-embryonic development 1/380 80/18722 0.806788552453363 0.840528787119309 IGF2R 1 GO:0030258 lipid modification 3/380 212/18722 0.807595383755044 0.841162432415793 MBOAT7/ALOX5/PTEN 3 GO:0016525 negative regulation of angiogenesis 2/380 149/18722 0.808662510931394 0.842066814308939 KLF2/ALOX5 2 GO:0010833 telomere maintenance via telomere lengthening 1/380 81/18722 0.810726989856417 0.843179961208724 MAPK1 1 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 1/380 81/18722 0.810726989856417 0.843179961208724 HSPA1A 1 GO:0044773 mitotic DNA damage checkpoint signaling 1/380 81/18722 0.810726989856417 0.843179961208724 NBN 1 GO:0051817 modulation of process of other organism involved in symbiotic interaction 1/380 81/18722 0.810726989856417 0.843179961208724 IGF2R 1 GO:2000243 positive regulation of reproductive process 1/380 81/18722 0.810726989856417 0.843179961208724 UBE2B 1 GO:2000181 negative regulation of blood vessel morphogenesis 2/380 151/18722 0.814531616344463 0.846776870191142 KLF2/ALOX5 2 GO:0035082 axoneme assembly 1/380 82/18722 0.814585352811975 0.846776870191142 UBE2B 1 GO:0060271 cilium assembly 5/380 337/18722 0.817248583241805 0.84908325035062 SNX10/ACTR2/ACTR3/UBE2B/CEP350 5 GO:0016125 sterol metabolic process 2/380 152/18722 0.817405528141553 0.84908325035062 LBR/CAT 2 GO:1901343 negative regulation of vasculature development 2/380 152/18722 0.817405528141553 0.84908325035062 KLF2/ALOX5 2 GO:0006163 purine nucleotide metabolic process 6/380 396/18722 0.817904156919421 0.849392865265755 LRRK2/ACSL1/TMSB4X/ELOVL5/STAT3/HIF1A 6 GO:1901292 nucleoside phosphate catabolic process 1/380 83/18722 0.818365265147353 0.84966337286076 TYMP 1 GO:0006112 energy reserve metabolic process 1/380 84/18722 0.822068317845674 0.85267188980564 PYGL 1 GO:0015844 monoamine transport 1/380 84/18722 0.822068317845674 0.85267188980564 ACTB 1 GO:0042440 pigment metabolic process 1/380 84/18722 0.822068317845674 0.85267188980564 TSPO 1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 1/380 84/18722 0.822068317845674 0.85267188980564 PTEN 1 GO:0007605 sensory perception of sound 2/380 154/18722 0.823034216700152 0.853464717856304 CDKN2D/MBP 2 GO:0030433 ubiquitin-dependent ERAD pathway 1/380 85/18722 0.825696069708462 0.855484347749942 NFE2L2 1 GO:0044774 mitotic DNA integrity checkpoint signaling 1/380 85/18722 0.825696069708462 0.855484347749942 NBN 1 GO:0006665 sphingolipid metabolic process 2/380 155/18722 0.82578984972887 0.855484347749942 ELOVL5/ST8SIA4 2 GO:0046434 organophosphate catabolic process 2/380 155/18722 0.82578984972887 0.855484347749942 PTEN/TYMP 2 GO:0048705 skeletal system morphogenesis 3/380 220/18722 0.827030134658272 0.856559701706477 ALPL/FGR/TGFBR2 3 GO:0001764 neuron migration 2/380 156/18722 0.82850691107696 0.857809954396866 CXCR4/STAT3 2 GO:0006493 protein O-linked glycosylation 1/380 86/18722 0.829250048004904 0.857809954396866 TET2 1 GO:0009798 axis specification 1/380 86/18722 0.829250048004904 0.857809954396866 BASP1 1 GO:0032413 negative regulation of ion transmembrane transporter activity 1/380 86/18722 0.829250048004904 0.857809954396866 PTEN 1 GO:0034103 regulation of tissue remodeling 1/380 86/18722 0.829250048004904 0.857809954396866 PPP3CA 1 GO:0070646 protein modification by small protein removal 2/380 157/18722 0.831185826138711 0.859602435579351 USP15/USP10 2 GO:0150104 transport across blood-brain barrier 1/380 87/18722 0.832731749108045 0.860780804850517 SLC2A3 1 GO:1901606 alpha-amino acid catabolic process 1/380 87/18722 0.832731749108045 0.860780804850517 GLUL 1 GO:0022613 ribonucleoprotein complex biogenesis 7/380 463/18722 0.83317424497006 0.861028044765301 CELF2/PTEN/GLUL/DDX3X/DICER1/ADAR/SF1 7 GO:0001843 neural tube closure 1/380 88/18722 0.836142639118184 0.863674165040368 VASP 1 GO:0010232 vascular transport 1/380 88/18722 0.836142639118184 0.863674165040368 SLC2A3 1 GO:0032200 telomere organization 2/380 159/18722 0.836430912211034 0.863761256574916 MAPK1/NBN 2 GO:0060606 tube closure 1/380 89/18722 0.839484154473722 0.866702923987375 VASP 1 GO:0003205 cardiac chamber development 2/380 161/18722 0.841528482365303 0.868601784747029 TGFBR2/HIF1A 2 GO:0042475 odontogenesis of dentin-containing tooth 1/380 90/18722 0.842757702549715 0.869658594127204 CSF3R 1 GO:0051952 regulation of amine transport 1/380 91/18722 0.845964662244386 0.872755260561504 RGS2 1 GO:0034502 protein localization to chromosome 1/380 92/18722 0.849106384553824 0.875783131657439 SPI1 1 GO:0072521 purine-containing compound metabolic process 6/380 416/18722 0.851764764112407 0.878311121503785 LRRK2/ACSL1/TMSB4X/ELOVL5/STAT3/HIF1A 6 GO:1901019 regulation of calcium ion transmembrane transporter activity 1/380 93/18722 0.85218419313512 0.87852971225103 VMP1 1 GO:0002042 cell migration involved in sprouting angiogenesis 1/380 94/18722 0.855199384858167 0.880994744557125 PTGS2 1 GO:0048704 embryonic skeletal system morphogenesis 1/380 94/18722 0.855199384858167 0.880994744557125 TGFBR2 1 GO:1990830 cellular response to leukemia inhibitory factor 1/380 94/18722 0.855199384858167 0.880994744557125 SNX10 1 GO:0009451 RNA modification 2/380 167/18722 0.855969420239548 0.88157356388971 APOBEC3A/ADAR 2 GO:0006942 regulation of striated muscle contraction 1/380 95/18722 0.858153230346352 0.882534951558232 RGS2 1 GO:0030516 regulation of axon extension 1/380 95/18722 0.858153230346352 0.882534951558232 PAK1 1 GO:0042773 ATP synthesis coupled electron transport 1/380 95/18722 0.858153230346352 0.882534951558232 BID 1 GO:0042775 mitochondrial ATP synthesis coupled electron transport 1/380 95/18722 0.858153230346352 0.882534951558232 BID 1 GO:1901379 regulation of potassium ion transmembrane transport 1/380 95/18722 0.858153230346352 0.882534951558232 PTEN 1 GO:1990823 response to leukemia inhibitory factor 1/380 95/18722 0.858153230346352 0.882534951558232 SNX10 1 GO:0035282 segmentation 1/380 96/18722 0.861046974506355 0.885081052678256 BASP1 1 GO:0043648 dicarboxylic acid metabolic process 1/380 96/18722 0.861046974506355 0.885081052678256 GLUL 1 GO:0043255 regulation of carbohydrate biosynthetic process 1/380 97/18722 0.863881837047297 0.887564187262325 PLEK 1 GO:0070252 actin-mediated cell contraction 1/380 97/18722 0.863881837047297 0.887564187262325 MYL6 1 GO:0003333 amino acid transmembrane transport 1/380 98/18722 0.866659012989419 0.890201532866891 RGS2 1 GO:0006813 potassium ion transport 3/380 241/18722 0.870226892695041 0.893432943166909 KCNJ15/PTEN/VPS4B 3 GO:0060047 heart contraction 3/380 241/18722 0.870226892695041 0.893432943166909 RGS2/CELF2/CXCR4 3 GO:0044782 cilium organization 5/380 368/18722 0.870818854915442 0.893824006438898 SNX10/ACTR2/ACTR3/UBE2B/CEP350 5 GO:0006664 glycolipid metabolic process 1/380 100/18722 0.872044964694413 0.894865622844884 ST8SIA4 1 GO:1903509 liposaccharide metabolic process 1/380 101/18722 0.874656011489393 0.897327569926739 ST8SIA4 1 GO:0001654 eye development 5/380 371/18722 0.875221726674782 0.897690484976436 VIM/AGTPBP1/STAT3/TGFBR2/HIF1A 5 GO:0006672 ceramide metabolic process 1/380 102/18722 0.877213914697278 0.899298215624055 ST8SIA4 1 GO:1990542 mitochondrial transmembrane transport 1/380 102/18722 0.877213914697278 0.899298215624055 SLC25A37 1 GO:0008380 RNA splicing 6/380 434/18722 0.877679884445898 0.89955815842894 IVNS1ABP/CELF2/PTBP3/DDX5/HSPA1A/SF1 6 GO:0003279 cardiac septum development 1/380 103/18722 0.879719753172844 0.901430717320831 TGFBR2 1 GO:0150063 visual system development 5/380 375/18722 0.880894119263594 0.902404752919018 VIM/AGTPBP1/STAT3/TGFBR2/HIF1A 5 GO:0006941 striated muscle contraction 2/380 179/18722 0.881309576876755 0.902404752919018 RGS2/CXCR4 2 GO:0007416 synapse assembly 2/380 179/18722 0.881309576876755 0.902404752919018 PTEN/SDCBP 2 GO:1901890 positive regulation of cell junction assembly 1/380 104/18722 0.88217458392607 0.903072120601138 IQGAP1 1 GO:0002062 chondrocyte differentiation 1/380 106/18722 0.88693534371956 0.907726239886983 TGFBR2 1 GO:0003015 heart process 3/380 251/18722 0.887236146079417 0.907814708539824 RGS2/CELF2/CXCR4 3 GO:0048880 sensory system development 5/380 381/18722 0.888990588379615 0.908989934124184 VIM/AGTPBP1/STAT3/TGFBR2/HIF1A 5 GO:0036503 ERAD pathway 1/380 107/18722 0.889243281482053 0.908989934124184 NFE2L2 1 GO:0042303 molting cycle 1/380 107/18722 0.889243281482053 0.908989934124184 PTGS2 1 GO:0042633 hair cycle 1/380 107/18722 0.889243281482053 0.908989934124184 PTGS2 1 GO:0006958 complement activation, classical pathway 1/380 108/18722 0.891504229805277 0.910422091445707 CD55 1 GO:0034440 lipid oxidation 1/380 108/18722 0.891504229805277 0.910422091445707 ALOX5 1 GO:0098659 inorganic cation import across plasma membrane 1/380 108/18722 0.891504229805277 0.910422091445707 KCNJ15 1 GO:0099587 inorganic ion import across plasma membrane 1/380 108/18722 0.891504229805277 0.910422091445707 KCNJ15 1 GO:0006821 chloride transport 1/380 109/18722 0.893719142917665 0.912024233796702 TSPO 1 GO:0032410 negative regulation of transporter activity 1/380 109/18722 0.893719142917665 0.912024233796702 PTEN 1 GO:0043266 regulation of potassium ion transport 1/380 109/18722 0.893719142917665 0.912024233796702 PTEN 1 GO:0043010 camera-type eye development 4/380 322/18722 0.895050438728145 0.912918606225824 VIM/AGTPBP1/TGFBR2/HIF1A 4 GO:0009063 cellular amino acid catabolic process 1/380 110/18722 0.895888955720077 0.912918606225824 GLUL 1 GO:0018958 phenol-containing compound metabolic process 1/380 110/18722 0.895888955720077 0.912918606225824 ITGB2 1 GO:0030317 flagellated sperm motility 1/380 110/18722 0.895888955720077 0.912918606225824 UBE2B 1 GO:0061387 regulation of extent of cell growth 1/380 110/18722 0.895888955720077 0.912918606225824 PAK1 1 GO:0097722 sperm motility 1/380 110/18722 0.895888955720077 0.912918606225824 UBE2B 1 GO:0010633 negative regulation of epithelial cell migration 1/380 112/18722 0.900096925695411 0.916985922617288 PTEN 1 GO:0001578 microtubule bundle formation 1/380 113/18722 0.902136859507111 0.918843097646132 UBE2B 1 GO:0022904 respiratory electron transport chain 1/380 114/18722 0.904135247028595 0.920657074096201 BID 1 GO:0000077 DNA damage checkpoint signaling 1/380 115/18722 0.906092932224701 0.921985480050843 NBN 1 GO:0034968 histone lysine methylation 1/380 115/18722 0.906092932224701 0.921985480050843 TET2 1 GO:0042471 ear morphogenesis 1/380 115/18722 0.906092932224701 0.921985480050843 MAPK1 1 GO:0031123 RNA 3'-end processing 1/380 116/18722 0.908010741960532 0.923714987317524 ZFP36L1 1 GO:0010906 regulation of glucose metabolic process 1/380 119/18722 0.913532937769574 0.929109508034136 MIDN 1 GO:0048593 camera-type eye morphogenesis 1/380 120/18722 0.915299184270007 0.930458964326327 HIF1A 1 GO:0048675 axon extension 1/380 120/18722 0.915299184270007 0.930458964326327 PAK1 1 GO:0048706 embryonic skeletal system development 1/380 121/18722 0.917029444993445 0.93189994740109 TGFBR2 1 GO:0009952 anterior/posterior pattern specification 2/380 201/18722 0.917376831337696 0.93189994740109 BASP1/BTG2 2 GO:0065004 protein-DNA complex assembly 2/380 201/18722 0.917376831337696 0.93189994740109 TAF7/UBN1 2 GO:0072329 monocarboxylic acid catabolic process 1/380 122/18722 0.918724451224427 0.933045096147589 CYP4F3 1 GO:0006643 membrane lipid metabolic process 2/380 203/18722 0.920088061760072 0.934205931803861 ELOVL5/ST8SIA4 2 GO:0031570 DNA integrity checkpoint signaling 1/380 123/18722 0.920384919425218 0.934283349416539 NBN 1 GO:0060294 cilium movement involved in cell motility 1/380 125/18722 0.923605035265783 0.937327420165491 UBE2B 1 GO:0008016 regulation of heart contraction 2/380 206/18722 0.923998648815257 0.937502222743798 RGS2/CELF2 2 GO:0006334 nucleosome assembly 1/380 129/18722 0.929660758533758 0.942795333426836 UBN1 1 GO:0007127 meiosis I 1/380 129/18722 0.929660758533758 0.942795333426836 UBE2B 1 GO:0006066 alcohol metabolic process 4/380 353/18722 0.930278094502199 0.9431955303368 PLEK/PTEN/LBR/CAT 4 GO:0006352 DNA-templated transcription, initiation 1/380 130/18722 0.931098337824737 0.943539386451335 TAF7 1 GO:0048562 embryonic organ morphogenesis 3/380 285/18722 0.931143422116316 0.943539386451335 TGFBR2/HIF1A/MAPK1 3 GO:0006457 protein folding 2/380 212/18722 0.931285628185734 0.943539386451335 B2M/HSPA1A 2 GO:0043583 ear development 2/380 213/18722 0.932434105126348 0.94432460578692 LRP10/MAPK1 2 GO:0018022 peptidyl-lysine methylation 1/380 131/18722 0.932506611901039 0.94432460578692 TET2 1 GO:0071103 DNA conformation change 3/380 290/18722 0.936080156813188 0.94771682144486 DDX3X/NBN/UBN1 3 GO:0061982 meiosis I cell cycle process 1/380 135/18722 0.93785839318523 0.949290223503693 UBE2B 1 GO:0071805 potassium ion transmembrane transport 2/380 219/18722 0.938952884971971 0.950170960061241 KCNJ15/PTEN 2 GO:0001539 cilium or flagellum-dependent cell motility 1/380 138/18722 0.941592543333406 0.952159603872248 UBE2B 1 GO:0007224 smoothened signaling pathway 1/380 138/18722 0.941592543333406 0.952159603872248 TGFBR2 1 GO:0060285 cilium-dependent cell motility 1/380 138/18722 0.941592543333406 0.952159603872248 UBE2B 1 GO:0042254 ribosome biogenesis 3/380 299/18722 0.94415294387943 0.954520820560847 PTEN/GLUL/DDX3X 3 GO:0006119 oxidative phosphorylation 1/380 141/18722 0.945102859676966 0.955025199411108 BID 1 GO:0016571 histone methylation 1/380 141/18722 0.945102859676966 0.955025199411108 TET2 1 GO:0006486 protein glycosylation 2/380 226/18722 0.945804785750986 0.955278623337807 ST8SIA4/TET2 2 GO:0043413 macromolecule glycosylation 2/380 226/18722 0.945804785750986 0.955278623337807 ST8SIA4/TET2 2 GO:0002181 cytoplasmic translation 1/380 148/18722 0.952496825166943 0.961808310582262 CPEB4 1 GO:0046395 carboxylic acid catabolic process 2/380 236/18722 0.954336512750862 0.96343626495826 CYP4F3/GLUL 2 GO:1901617 organic hydroxy compound biosynthetic process 2/380 237/18722 0.955115435792639 0.963992819490426 PLEK/LBR 2 GO:0031497 chromatin assembly 1/380 151/18722 0.955353294401875 0.964003145530603 UBN1 1 GO:0009100 glycoprotein metabolic process 4/380 387/18722 0.956355730601327 0.964784783014917 ITM2B/ST8SIA4/HIF1A/TET2 4 GO:0007338 single fertilization 1/380 153/18722 0.957161772020299 0.965059686820771 MYH9 1 GO:0016054 organic acid catabolic process 2/380 240/18722 0.957376801846867 0.965059686820771 CYP4F3/GLUL 2 GO:0070085 glycosylation 2/380 240/18722 0.957376801846867 0.965059686820771 ST8SIA4/TET2 2 GO:0009101 glycoprotein biosynthetic process 3/380 317/18722 0.957539741209181 0.965059686820771 ITM2B/ST8SIA4/TET2 3 GO:0071824 protein-DNA complex subunit organization 2/380 241/18722 0.95810608978956 0.965400735250723 TAF7/UBN1 2 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 3/380 320/18722 0.959455601032443 0.966300706390581 CELF2/DDX5/SF1 3 GO:0000398 mRNA splicing, via spliceosome 3/380 320/18722 0.959455601032443 0.966300706390581 CELF2/DDX5/SF1 3 GO:1902600 proton transmembrane transport 1/380 157/18722 0.960562462222318 0.967183726155075 TMSB4X 1 GO:0098656 anion transmembrane transport 2/380 245/18722 0.960905655615845 0.967183726155075 RGS2/SLC16A3 2 GO:0034470 ncRNA processing 4/380 395/18722 0.961017501690804 0.967183726155075 STAT3/DDX3X/DICER1/ADAR 4 GO:0003007 heart morphogenesis 2/380 246/18722 0.961577044876906 0.967516936339676 TGFBR2/HIF1A 2 GO:0000375 RNA splicing, via transesterification reactions 3/380 324/18722 0.961884362235903 0.967596264624477 CELF2/DDX5/SF1 3 GO:0035637 multicellular organismal signaling 1/380 160/18722 0.962935053169839 0.968423165560263 TYMP 1 GO:0007286 spermatid development 1/380 165/18722 0.966577193378133 0.971855273968754 UBE2B 1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 1/380 167/18722 0.967932042019134 0.972524839371538 PECAM1 1 GO:0034728 nucleosome organization 1/380 167/18722 0.967932042019134 0.972524839371538 UBN1 1 GO:0055088 lipid homeostasis 1/380 167/18722 0.967932042019134 0.972524839371538 DDX3X 1 GO:0005996 monosaccharide metabolic process 2/380 257/18722 0.968269278291297 0.972632920674488 SLC2A3/MIDN 2 GO:0006790 sulfur compound metabolic process 3/380 339/18722 0.969828656679058 0.973968309470194 ACSL1/ELOVL5/NFE2L2 3 GO:0048515 spermatid differentiation 1/380 172/18722 0.971084299643783 0.974998105498204 UBE2B 1 GO:0003341 cilium movement 1/380 175/18722 0.972825266938127 0.97651457821355 UBE2B 1 GO:0006333 chromatin assembly or disassembly 1/380 177/18722 0.973927427407096 0.977389254755699 UBN1 1 GO:0006399 tRNA metabolic process 1/380 179/18722 0.974984999006653 0.978218780097886 DICER1 1 GO:0007389 pattern specification process 4/380 436/18722 0.978469417286296 0.981482231692909 BASP1/BTG2/TGFBR2/HIF1A 4 GO:0048839 inner ear development 1/380 188/18722 0.979238862702709 0.982021450046406 LRP10 1 GO:0009566 fertilization 1/380 190/18722 0.980081483264064 0.982633778793397 MYH9 1 GO:1901605 alpha-amino acid metabolic process 1/380 195/18722 0.982041790039405 0.98436614930577 GLUL 1 GO:0006006 glucose metabolic process 1/380 196/18722 0.982410123810929 0.98450233656869 MIDN 1 GO:0006323 DNA packaging 1/380 199/18722 0.983470525372808 0.985331836989316 UBN1 1 GO:0016051 carbohydrate biosynthetic process 1/380 202/18722 0.98446715893993 0.986097071454731 PLEK 1 GO:0022412 cellular process involved in reproduction in multicellular organism 3/380 384/18722 0.985301677079476 0.986699598588693 ARRB2/PRKAR1A/UBE2B 3 GO:0044242 cellular lipid catabolic process 1/380 214/18722 0.987889165543503 0.989056883233271 SORL1 1 GO:0034660 ncRNA metabolic process 4/380 485/18722 0.98970959622565 0.990645270625296 STAT3/DDX3X/DICER1/ADAR 4 GO:0003002 regionalization 2/380 331/18722 0.991530227656364 0.992233108252528 BASP1/BTG2 2 GO:0019318 hexose metabolic process 1/380 237/18722 0.99248673409816 0.992955662392087 MIDN 1 GO:0007281 germ cell development 1/380 278/18722 0.996796934280188 0.99703236104785 UBE2B 1 GO:0006520 cellular amino acid metabolic process 1/380 284/18722 0.997173094542937 0.997173094542937 GLUL 1