ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0045296	cadherin binding	20/240	332/18367	1.56935203341407e-08	7.43872863838269e-06	S100P/NDRG1/EZR/ANXA1/PRDX6/COBLL1/BZW2/EPS8L1/S100A11/KRT18/LDHA/EIF4H/EFHD2/GIPC1/TAGLN2/ALDOA/SNX9/RAB1A/CHMP2B/RDX	20
GO:0051427	hormone receptor binding	6/240	33/18367	3.8541480568092e-06	0.000728913802883341	CSH1/CSH2/CRH/CSHL1/GH2/LEP	6
GO:0005179	hormone activity	10/240	122/18367	4.61337849926165e-06	0.000728913802883341	CSH1/CSH2/CRH/CSHL1/CGA/INHBA/GH2/LEP/INHA/INSL4	10
GO:0008603	cAMP-dependent protein kinase regulator activity	3/240	11/18367	0.000336438692441298	0.0398679850542938	PKIG/PKIB/PRKAG2	3
GO:0098632	cell-cell adhesion mediator activity	5/240	49/18367	0.000436039629975827	0.0413365569217084	GLDN/ANXA1/CD200/S100A11/KRT18	5
GO:0044548	S100 protein binding	3/240	14/18367	0.000720976997701506	0.0499285077716048	EZR/S100A6/S100A11	3
GO:0030291	protein serine/threonine kinase inhibitor activity	4/240	34/18367	0.000969051725348302	0.0499285077716048	HSPB1/PKIG/PKIB/PRKAG2	4
GO:0098631	cell adhesion mediator activity	5/240	59/18367	0.00102989664529187	0.0499285077716048	GLDN/ANXA1/CD200/S100A11/KRT18	5
GO:0048306	calcium-dependent protein binding	6/240	88/18367	0.00103744238503634	0.0499285077716048	S100P/CALM1/ANXA4/ANXA1/S100A6/S100A11	6
GO:0005484	SNAP receptor activity	4/240	36/18367	0.00120598021909508	0.0499285077716048	STX3/BET1/VAMP8/SNAP23	4
GO:0097718	disordered domain specific binding	4/240	36/18367	0.00120598021909508	0.0499285077716048	CALM1/EZR/GAPDH/AP2M1	4
GO:0008083	growth factor activity	8/240	162/18367	0.00133050708409671	0.0499285077716048	CSH1/CSH2/CSHL1/INHBA/GH2/GDF15/INHA/PGF	8
GO:0015631	tubulin binding	13/240	375/18367	0.00136934725955878	0.0499285077716048	CRYAB/TPPP3/CCSAP/NDRG1/EZR/KIF2A/CAPN6/GAPDH/MAP1LC3B/SBDS/ALDOA/BEX4/KATNBL1	13
GO:0098641	cadherin binding involved in cell-cell adhesion	3/240	18/18367	0.00155505105321905	0.0526495856589879	ANXA1/S100A11/KRT18	3
GO:0048018	receptor ligand activity	15/240	487/18367	0.0019368714606675	0.0612051381570929	CSH1/CSH2/CRH/CSHL1/CGA/INHBA/GH2/EBI3/SEMA3B/LEP/GDF15/INHA/PGF/MIF/INSL4	15
GO:0004860	protein kinase inhibitor activity	5/240	70/18367	0.00221717949968413	0.0631308691418184	HSPB1/SH3BP5/PKIG/PKIB/PRKAG2	5
GO:0030546	signaling receptor activator activity	15/240	495/18367	0.00226418728989644	0.0631308691418184	CSH1/CSH2/CRH/CSHL1/CGA/INHBA/GH2/EBI3/SEMA3B/LEP/GDF15/INHA/PGF/MIF/INSL4	15
GO:0004602	glutathione peroxidase activity	3/240	22/18367	0.00282392043270752	0.0670575812797073	PRDX6/GSTP1/GPX4	3
GO:0017022	myosin binding	5/240	74/18367	0.00282943380927035	0.0670575812797073	LIMCH1/MYL12B/GSN/GIPC1/RAB25	5
GO:0019210	kinase inhibitor activity	5/240	74/18367	0.00282943380927035	0.0670575812797073	HSPB1/SH3BP5/PKIG/PKIB/PRKAG2	5
GO:0008017	microtubule binding	10/240	271/18367	0.00308681395403246	0.0696738006767326	CRYAB/CCSAP/NDRG1/EZR/KIF2A/CAPN6/GAPDH/MAP1LC3B/SBDS/KATNBL1	10
GO:0019207	kinase regulator activity	9/240	233/18367	0.00364385076323189	0.0785084209896326	HSPB1/CALM1/SH3BP5/PKIG/RGCC/PKIB/GSTP1/PRKAG2/STK3	9
GO:0097602	cullin family protein binding	3/240	26/18367	0.00458802230583016	0.0945531553462389	SKP1/RBX1/RNF7	3
GO:0003779	actin binding	13/240	440/18367	0.00537986733217359	0.0999991136375837	PDLIM4/LIMCH1/EZR/COBLL1/MARCKS/EPS8L1/PDLIM2/DSTN/GSN/GIPC1/ALDOA/PHACTR2/RDX	13
GO:0016209	antioxidant activity	5/240	86/18367	0.00539357950743346	0.0999991136375837	GLRX/PRDX6/GSTP1/GPX4/TXN	5
GO:0019887	protein kinase regulator activity	8/240	204/18367	0.00548518344847505	0.0999991136375837	HSPB1/CALM1/SH3BP5/PKIG/RGCC/PKIB/PRKAG2/STK3	8
GO:0140678	molecular function inhibitor activity	6/240	128/18367	0.00675479070718237	0.118584103526091	CALM1/ANXA4/ANXA1/DYNLL1/OAZ1/RASA1	6
GO:0047134	protein-disulfide reductase (NAD(P)) activity	2/240	11/18367	0.00865259921607303	0.140231586578501	GLRX/TXN	2
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/240	11/18367	0.00865259921607303	0.140231586578501	GLDN/CD200	2
GO:0044389	ubiquitin-like protein ligase binding	10/240	316/18367	0.00887541687205704	0.140231586578501	PRDX6/SQSTM1/CEBPB/UBC/MAP1LC3B/TPI1/UBE2A/RBX1/SNX9/UBE2B	10
GO:0045505	dynein intermediate chain binding	3/240	34/18367	0.0097817353209672	0.149565888456079	DYNLL1/DYNLRB1/DYNLT3	3
GO:0042805	actinin binding	3/240	36/18367	0.0114509950806764	0.153966171870841	PDLIM4/PDLIM2/CSRP1	3
GO:0004859	phospholipase inhibitor activity	2/240	13/18367	0.0120619538334621	0.153966171870841	ANXA4/ANXA1	2
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/240	13/18367	0.0120619538334621	0.153966171870841	PPP1R14B/PPP1R11	2
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/240	13/18367	0.0120619538334621	0.153966171870841	GLRX/TXN	2
GO:0032036	myosin heavy chain binding	2/240	13/18367	0.0120619538334621	0.153966171870841	LIMCH1/MYL12B	2
GO:0045159	myosin II binding	2/240	13/18367	0.0120619538334621	0.153966171870841	LIMCH1/GSN	2
GO:0015035	protein-disulfide reductase activity	3/240	37/18367	0.0123432796014598	0.153966171870841	GLRX/TXN/GLRX5	3
GO:0004857	enzyme inhibitor activity	4/240	70/18367	0.0133041478024736	0.157020218433348	ANXA4/ANXA1/DYNLL1/OAZ1	4
GO:0003924	GTPase activity	10/240	337/18367	0.0134821344292058	0.157020218433348	GNG11/RHOBTB3/RHOD/RAB2A/ARF1/RAB1A/RASA1/RHEB/RAB25/RHOBTB1	10
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/240	14/18367	0.0139521166394222	0.157020218433348	HSD3B1/MIF	2
GO:0140666	annealing activity	2/240	14/18367	0.0139521166394222	0.157020218433348	ANXA1/EIF4H	2
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/240	39/18367	0.0142444501954303	0.157020218433348	UBE2A/UBE2B/UFC1	3
GO:0030276	clathrin binding	4/240	72/18367	0.0146309154855782	0.157614862276456	CLTB/DAB2/AP2M1/NSG1	4
GO:0048185	activin binding	2/240	15/18367	0.0159612796319304	0.164470577076848	FSTL3/ENG	2
GO:0051371	muscle alpha-actinin binding	2/240	15/18367	0.0159612796319304	0.164470577076848	PDLIM4/PDLIM2	2
GO:0031625	ubiquitin protein ligase binding	9/240	297/18367	0.0164658207990126	0.166059554441106	PRDX6/SQSTM1/UBC/MAP1LC3B/TPI1/UBE2A/RBX1/SNX9/UBE2B	9
GO:0015036	disulfide oxidoreductase activity	3/240	42/18367	0.017390665644459	0.171732823239033	GLRX/TXN/GLRX5	3
GO:0016853	isomerase activity	6/240	158/18367	0.017760886544863	0.171809392291123	HSD3B1/BPGM/FKBP2/MIF/TPI1/GALE	6
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/240	17/18367	0.0203230512143153	0.185252428376643	ATP6V1F/ATP6V1G1	2
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/240	17/18367	0.0203230512143153	0.185252428376643	ATP6V1F/ATP6V1G1	2
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/240	17/18367	0.0203230512143153	0.185252428376643	ATP6V1F/ATP6V1G1	2
GO:0004864	protein phosphatase inhibitor activity	3/240	46/18367	0.022140571799647	0.198011906283635	PPP1R14B/PPP1R11/PHACTR2	3
GO:0055102	lipase inhibitor activity	2/240	18/18367	0.0226690512344523	0.198983894169082	ANXA4/ANXA1	2
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/240	124/18367	0.0234857752174531	0.20240468096496	HSD3B1/HPGD/HSD17B1/LDHA/RDH13	5
GO:0035615	clathrin adaptor activity	2/240	19/18367	0.0251208319519931	0.212629899022227	DAB2/AP2M1	2
GO:0019212	phosphatase inhibitor activity	3/240	49/18367	0.026120893517902	0.217215851359396	PPP1R14B/PPP1R11/PHACTR2	3
GO:0005525	GTP binding	10/240	377/18367	0.026918381202302	0.218634496645241	RHOBTB3/RHOD/TGM2/RAB2A/DAPK1/ARF1/RAB1A/RHEB/RAB25/RHOBTB1	10
GO:0009678	pyrophosphate hydrolysis-driven proton transmembrane transporter activity	2/240	20/18367	0.0276752527399039	0.218634496645241	ATP6V1F/ATP6V1G1	2
GO:0140312	cargo adaptor activity	2/240	20/18367	0.0276752527399039	0.218634496645241	DAB2/AP2M1	2
GO:0004601	peroxidase activity	3/240	51/18367	0.0289730924887425	0.220424275796172	PRDX6/GSTP1/GPX4	3
GO:0016860	intramolecular oxidoreductase activity	3/240	51/18367	0.0289730924887425	0.220424275796172	HSD3B1/MIF/TPI1	3
GO:0019888	protein phosphatase regulator activity	4/240	89/18367	0.0292968974159469	0.220424275796172	CALM1/PPP1R14B/PPP1R11/PHACTR2	4
GO:0051428	peptide hormone receptor binding	2/240	21/18367	0.0303292363854893	0.22462590698003	CRH/LEP	2
GO:0061134	peptidase regulator activity	7/240	230/18367	0.0318492587737644	0.230237918250749	TFPI2/TIMP2/GPC3/TFPI/GAPDH/BAD/FBLN1	7
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	5/240	136/18367	0.0331776316439033	0.230237918250749	HSD3B1/HPGD/HSD17B1/LDHA/RDH13	5
GO:0005080	protein kinase C binding	3/240	55/18367	0.035150955155452	0.230237918250749	HSPB1/SQSTM1/MARCKS	3
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/240	55/18367	0.035150955155452	0.230237918250749	PRDX6/GSTP1/GPX4	3
GO:0020037	heme binding	5/240	139/18367	0.0359369052217504	0.230237918250749	STEAP4/CYP11A1/CYP19A1/HEBP2/PGRMC2	5
GO:0099106	ion channel regulator activity	5/240	139/18367	0.0359369052217504	0.230237918250749	CALM1/SRI/PRKCZ/VAMP8/RASA1	5
GO:0051287	NAD binding	3/240	56/18367	0.0367932472515028	0.230237918250749	HPGD/GAPDH/LDHA	3
GO:0019001	guanyl nucleotide binding	10/240	398/18367	0.0369252358113081	0.230237918250749	RHOBTB3/RHOD/TGM2/RAB2A/DAPK1/ARF1/RAB1A/RHEB/RAB25/RHOBTB1	10
GO:0032561	guanyl ribonucleotide binding	10/240	398/18367	0.0369252358113081	0.230237918250749	RHOBTB3/RHOD/TGM2/RAB2A/DAPK1/ARF1/RAB1A/RHEB/RAB25/RHOBTB1	10
GO:0019838	growth factor binding	5/240	141/18367	0.0378527965368077	0.230237918250749	HTRA1/HTRA4/ENG/FLT1/SEC61B	5
GO:0008022	protein C-terminus binding	6/240	189/18367	0.0381131758586934	0.230237918250749	SDC1/EZR/DAB2/SASH1/TAX1BP3/FBLN1	6
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/240	57/18367	0.0384743214603523	0.230237918250749	GLRX/TXN/GLRX5	3
GO:0001965	G-protein alpha-subunit binding	2/240	24/18367	0.0388587203798733	0.230237918250749	NUCB2/SASH1	2
GO:0003707	steroid hormone receptor activity	2/240	24/18367	0.0388587203798733	0.230237918250749	PAQR7/PGRMC2	2
GO:0051537	2 iron, 2 sulfur cluster binding	2/240	24/18367	0.0388587203798733	0.230237918250749	FDX1/GLRX5	2
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/240	24/18367	0.0388587203798733	0.230237918250749	INHBA/GDF15	2
GO:0016247	channel regulator activity	5/240	145/18367	0.0418694256376444	0.243841233209921	CALM1/SRI/PRKCZ/VAMP8/RASA1	5
GO:0005496	steroid binding	4/240	100/18367	0.0421835044793534	0.243841233209921	HSD17B1/PAQR7/PGRMC2/INSIG1	4
GO:0030295	protein kinase activator activity	4/240	101/18367	0.0434905113787379	0.24836749871713	CALM1/RGCC/PRKAG2/STK3	4
GO:0046906	tetrapyrrole binding	5/240	149/18367	0.0461343133949512	0.26032933987151	STEAP4/CYP11A1/CYP19A1/HEBP2/PGRMC2	5
GO:0051393	alpha-actinin binding	2/240	27/18367	0.0481793486829608	0.268670720890863	PDLIM4/PDLIM2	2
GO:0001968	fibronectin binding	2/240	28/18367	0.0514492086330142	0.279048857026078	FSTL3/FBLN1	2
GO:0019208	phosphatase regulator activity	4/240	107/18367	0.0518065388571621	0.279048857026078	CALM1/PPP1R14B/PPP1R11/PHACTR2	4
GO:0019209	kinase activator activity	4/240	107/18367	0.0518065388571621	0.279048857026078	CALM1/RGCC/PRKAG2/STK3	4
GO:0005520	insulin-like growth factor binding	2/240	29/18367	0.0547961672069615	0.288593147289997	HTRA1/HTRA4	2
GO:0033612	receptor serine/threonine kinase binding	2/240	29/18367	0.0547961672069615	0.288593147289997	INHBA/GDF15	2
GO:0000149	SNARE binding	4/240	110/18367	0.0562677768338157	0.293087101310205	STX3/DAPK1/VAMP8/SNAP23	4
GO:0097110	scaffold protein binding	3/240	67/18367	0.0573663570504029	0.293565698104845	KRT8/DYNLL1/KRT18	3
GO:0004222	metalloendopeptidase activity	4/240	111/18367	0.0577994576502839	0.293565698104845	PAPPA2/PAPPA/MMP11/ADAM12	4
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/240	30/18367	0.0582176700883025	0.293565698104845	HSD3B1/HSD17B1	2
GO:0019843	rRNA binding	3/240	68/18367	0.0594575723157134	0.296661992396296	RPS13/SBDS/RPS4Y1	3
GO:0071889	14-3-3 protein binding	2/240	32/18367	0.0652743560388973	0.318946866416009	PRKCZ/BAD	2
GO:0005126	cytokine receptor binding	7/240	271/18367	0.0657787694968051	0.318946866416009	CSH1/CSH2/CSHL1/GH2/PGF/ENG/MIF	7
GO:0048029	monosaccharide binding	3/240	71/18367	0.0659426010733522	0.318946866416009	ENG/ALDOA/UGP2	3
GO:0008200	ion channel inhibitor activity	2/240	33/18367	0.0689046921967653	0.32990731415421	CALM1/RASA1	2
GO:0016229	steroid dehydrogenase activity	2/240	34/18367	0.0725998770015027	0.334731860956139	HSD3B1/HSD17B1	2
GO:0016248	channel inhibitor activity	2/240	34/18367	0.0725998770015027	0.334731860956139	CALM1/RASA1	2
GO:0043548	phosphatidylinositol 3-kinase binding	2/240	34/18367	0.0725998770015027	0.334731860956139	CALM1/GSN	2
GO:0019905	syntaxin binding	3/240	74/18367	0.0727370921486968	0.334731860956139	DAPK1/VAMP8/SNAP23	3
GO:0019003	GDP binding	3/240	75/18367	0.0750689249461783	0.342141061773928	RAB2A/ARF1/RHEB	3
GO:0061631	ubiquitin conjugating enzyme activity	2/240	36/18367	0.0801756486541262	0.361935785352913	UBE2A/UBE2B	2
GO:0009055	electron transfer activity	4/240	126/18367	0.0833901646391286	0.368893941014254	STEAP4/CYP19A1/FDX1/NDUFA6	4
GO:0042056	chemoattractant activity	2/240	37/18367	0.0840517840285643	0.368893941014254	PGF/MIF	2
GO:0071855	neuropeptide receptor binding	2/240	37/18367	0.0840517840285643	0.368893941014254	KISS1/CRH	2
GO:0042826	histone deacetylase binding	4/240	127/18367	0.0852659222741382	0.370789423467353	CEBPB/HES1/BEX4/GCM1	4
GO:0008395	steroid hydroxylase activity	2/240	38/18367	0.0879838633826746	0.37913046584898	CYP11A1/CYP19A1	2
GO:0005504	fatty acid binding	2/240	39/18367	0.0919697776090122	0.392735807087133	STX3/GSTP1	2
GO:0030674	protein-macromolecule adaptor activity	7/240	296/18367	0.0943059387464605	0.399116205051985	DAB2/SKP1/STX3/BET1/AP2M1/VAMP8/SNAP23	7
GO:0031492	nucleosomal DNA binding	2/240	40/18367	0.0960074627525708	0.402721569422288	MBD2/SMARCB1	2
GO:0003714	transcription corepressor activity	5/240	187/18367	0.0990455666612331	0.408239987803691	BASP1/RYBP/SAP18/TCF25/TFAP2A	5
GO:0030414	peptidase inhibitor activity	5/240	187/18367	0.0990455666612331	0.408239987803691	TFPI2/TIMP2/GPC3/TFPI/GAPDH	5
GO:0042562	hormone binding	3/240	86/18367	0.102795472859994	0.41868705555613	INHBA/EBI3/SEC61B	3
GO:0001046	core promoter sequence-specific DNA binding	2/240	42/18367	0.104230110876843	0.41868705555613	CEBPB/SMARCB1	2
GO:0008307	structural constituent of muscle	2/240	42/18367	0.104230110876843	0.41868705555613	KRT19/CSRP1	2
GO:0005246	calcium channel regulator activity	2/240	43/18367	0.108411164471274	0.42577245663595	CALM1/SRI	2
GO:0016504	peptidase activator activity	2/240	43/18367	0.108411164471274	0.42577245663595	BAD/FBLN1	2
GO:0051117	ATPase binding	3/240	89/18367	0.110972684693727	0.42577245663595	EZR/ATP6V1G1/RDX	3
GO:0060090	molecular adaptor activity	8/240	369/18367	0.111881297226485	0.42577245663595	DAB2/SKP1/STX3/BET1/AP2M1/SASH1/VAMP8/SNAP23	8
GO:0043130	ubiquitin binding	3/240	92/18367	0.11939082641799	0.42577245663595	HSPB1/SQSTM1/UBE2A	3
GO:0001094	TFIID-class transcription factor complex binding	1/240	10/18367	0.12327579919109	0.42577245663595	EDF1	1
GO:0004955	prostaglandin receptor activity	1/240	10/18367	0.12327579919109	0.42577245663595	HPGD	1
GO:0005528	FK506 binding	1/240	10/18367	0.12327579919109	0.42577245663595	FKBP2	1
GO:0015232	heme transmembrane transporter activity	1/240	10/18367	0.12327579919109	0.42577245663595	PGRMC2	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/240	10/18367	0.12327579919109	0.42577245663595	MAN1C1	1
GO:0016868	intramolecular transferase activity, phosphotransferases	1/240	10/18367	0.12327579919109	0.42577245663595	BPGM	1
GO:0019869	chloride channel inhibitor activity	1/240	10/18367	0.12327579919109	0.42577245663595	VAMP8	1
GO:0030957	Tat protein binding	1/240	10/18367	0.12327579919109	0.42577245663595	SMARCB1	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/240	10/18367	0.12327579919109	0.42577245663595	ACSL4	1
GO:0034713	type I transforming growth factor beta receptor binding	1/240	10/18367	0.12327579919109	0.42577245663595	ENG	1
GO:0070567	cytidylyltransferase activity	1/240	10/18367	0.12327579919109	0.42577245663595	NANS	1
GO:0019829	ATPase-coupled cation transmembrane transporter activity	2/240	47/18367	0.125556585342708	0.42577245663595	ATP6V1F/ATP6V1G1	2
GO:0035254	glutamate receptor binding	2/240	47/18367	0.125556585342708	0.42577245663595	CALM1/SQSTM1	2
GO:0043539	protein serine/threonine kinase activator activity	2/240	49/18367	0.134357096150848	0.42577245663595	CALM1/STK3	2
GO:0004674	protein serine/threonine kinase activity	8/240	386/18367	0.134389045101178	0.42577245663595	SQSTM1/ENG/PRKAG2/PRKCZ/STK3/CSNK2A2/DAPK1/PIM3	8
GO:0004954	prostanoid receptor activity	1/240	11/18367	0.134738119188592	0.42577245663595	HPGD	1
GO:0005436	sodium:phosphate symporter activity	1/240	11/18367	0.134738119188592	0.42577245663595	MFSD2A	1
GO:0005536	glucose binding	1/240	11/18367	0.134738119188592	0.42577245663595	UGP2	1
GO:0016832	aldehyde-lyase activity	1/240	11/18367	0.134738119188592	0.42577245663595	ALDOA	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/240	11/18367	0.134738119188592	0.42577245663595	GALE	1
GO:0019855	calcium channel inhibitor activity	1/240	11/18367	0.134738119188592	0.42577245663595	CALM1	1
GO:0030283	testosterone dehydrogenase [NAD(P)] activity	1/240	11/18367	0.134738119188592	0.42577245663595	HSD17B1	1
GO:0035197	siRNA binding	1/240	11/18367	0.134738119188592	0.42577245663595	MBD2	1
GO:0042608	T cell receptor binding	1/240	11/18367	0.134738119188592	0.42577245663595	EPS8L1	1
GO:0043560	insulin receptor substrate binding	1/240	11/18367	0.134738119188592	0.42577245663595	PRKCZ	1
GO:0047676	arachidonate-CoA ligase activity	1/240	11/18367	0.134738119188592	0.42577245663595	ACSL4	1
GO:0070697	activin receptor binding	1/240	11/18367	0.134738119188592	0.42577245663595	INHBA	1
GO:0005506	iron ion binding	4/240	151/18367	0.136081555853758	0.427169917050871	CYP11A1/CYP19A1/FDX1/CDO1	4
GO:0051018	protein kinase A binding	2/240	51/18367	0.143291414422965	0.428280703136106	EZR/RDX	2
GO:0003995	acyl-CoA dehydrogenase activity	1/240	12/18367	0.146051196732432	0.428280703136106	TECR	1
GO:0005024	transforming growth factor beta-activated receptor activity	1/240	12/18367	0.146051196732432	0.428280703136106	ENG	1
GO:0005527	macrolide binding	1/240	12/18367	0.146051196732432	0.428280703136106	FKBP2	1
GO:0035256	G protein-coupled glutamate receptor binding	1/240	12/18367	0.146051196732432	0.428280703136106	CALM1	1
GO:0043422	protein kinase B binding	1/240	12/18367	0.146051196732432	0.428280703136106	BAD	1
GO:0017046	peptide hormone binding	2/240	52/18367	0.147804728735974	0.428280703136106	INHBA/EBI3	2
GO:0050661	NADP binding	2/240	53/18367	0.15234673973894	0.428280703136106	GAPDH/HSD17B1	2
GO:0004620	phospholipase activity	3/240	104/18367	0.155222962328553	0.428280703136106	LGALS13/PLCL2/PRDX6	3
GO:0005544	calcium-dependent phospholipid binding	2/240	54/18367	0.15691593618927	0.428280703136106	ANXA4/ANXA1	2
GO:0015459	potassium channel regulator activity	2/240	54/18367	0.15691593618927	0.428280703136106	PRKCZ/RASA1	2
GO:0008179	adenylate cyclase binding	1/240	13/18367	0.157216966974014	0.428280703136106	CALM1	1
GO:0031386	protein tag	1/240	13/18367	0.157216966974014	0.428280703136106	UBC	1
GO:0031432	titin binding	1/240	13/18367	0.157216966974014	0.428280703136106	CALM1	1
GO:0034236	protein kinase A catalytic subunit binding	1/240	13/18367	0.157216966974014	0.428280703136106	EZR	1
GO:0034450	ubiquitin-ubiquitin ligase activity	1/240	13/18367	0.157216966974014	0.428280703136106	RBX1	1
GO:0052650	NADP-retinol dehydrogenase activity	1/240	13/18367	0.157216966974014	0.428280703136106	RDH13	1
GO:0070679	inositol 1,4,5 trisphosphate binding	1/240	13/18367	0.157216966974014	0.428280703136106	PLCL2	1
GO:0070700	BMP receptor binding	1/240	13/18367	0.157216966974014	0.428280703136106	GDF15	1
GO:0072542	protein phosphatase activator activity	1/240	13/18367	0.157216966974014	0.428280703136106	CALM1	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/240	13/18367	0.157216966974014	0.428280703136106	HSD17B1	1
GO:0140299	small molecule sensor activity	1/240	13/18367	0.157216966974014	0.428280703136106	EFHD1	1
GO:0140333	glycerophospholipid flippase activity	1/240	13/18367	0.157216966974014	0.428280703136106	MFSD2A	1
GO:0000287	magnesium ion binding	5/240	221/18367	0.163955312125212	0.443293702098478	ALPP/S100P/STK3/ARF1/RHEB	5
GO:0005172	vascular endothelial growth factor receptor binding	1/240	14/18367	0.168237340076674	0.443293702098478	PGF	1
GO:0035259	glucocorticoid receptor binding	1/240	14/18367	0.168237340076674	0.443293702098478	CEBPB	1
GO:0036041	long-chain fatty acid binding	1/240	14/18367	0.168237340076674	0.443293702098478	STX3	1
GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	1/240	14/18367	0.168237340076674	0.443293702098478	HSD17B1	1
GO:0047485	protein N-terminus binding	3/240	110/18367	0.174258902007913	0.443293702098478	CALM1/GLRX/CSNK2A2	3
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	2/240	58/18367	0.175435538553826	0.443293702098478	GSTP1/NANS	2
GO:0032182	ubiquitin-like protein binding	3/240	111/18367	0.177493886573403	0.443293702098478	HSPB1/SQSTM1/UBE2A	3
GO:0004467	long-chain fatty acid-CoA ligase activity	1/240	15/18367	0.179114201537013	0.443293702098478	ACSL4	1
GO:0004559	alpha-mannosidase activity	1/240	15/18367	0.179114201537013	0.443293702098478	MAN1C1	1
GO:0004953	icosanoid receptor activity	1/240	15/18367	0.179114201537013	0.443293702098478	HPGD	1
GO:0005545	1-phosphatidylinositol binding	1/240	15/18367	0.179114201537013	0.443293702098478	SNX9	1
GO:0010851	cyclase regulator activity	1/240	15/18367	0.179114201537013	0.443293702098478	CALM1	1
GO:0050998	nitric-oxide synthase binding	1/240	15/18367	0.179114201537013	0.443293702098478	CALM1	1
GO:0070742	C2H2 zinc finger domain binding	1/240	15/18367	0.179114201537013	0.443293702098478	MBD2	1
GO:0071933	Arp2/3 complex binding	1/240	15/18367	0.179114201537013	0.443293702098478	SNX9	1
GO:0005507	copper ion binding	2/240	61/18367	0.189541603288183	0.443293702098478	RNF7/COX17	2
GO:0004698	calcium-dependent protein kinase C activity	1/240	16/18367	0.189849412502091	0.443293702098478	PRKCZ	1
GO:0005159	insulin-like growth factor receptor binding	1/240	16/18367	0.189849412502091	0.443293702098478	INSL4	1
GO:0005521	lamin binding	1/240	16/18367	0.189849412502091	0.443293702098478	BNIP3L	1
GO:0005523	tropomyosin binding	1/240	16/18367	0.189849412502091	0.443293702098478	S100A6	1
GO:0008191	metalloendopeptidase inhibitor activity	1/240	16/18367	0.189849412502091	0.443293702098478	TIMP2	1
GO:0015923	mannosidase activity	1/240	16/18367	0.189849412502091	0.443293702098478	MAN1C1	1
GO:0016004	phospholipase activator activity	1/240	16/18367	0.189849412502091	0.443293702098478	ARF1	1
GO:0016208	AMP binding	1/240	16/18367	0.189849412502091	0.443293702098478	PRKAG2	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/240	16/18367	0.189849412502091	0.443293702098478	MAOA	1
GO:0036122	BMP binding	1/240	16/18367	0.189849412502091	0.443293702098478	ENG	1
GO:0070403	NAD+ binding	1/240	16/18367	0.189849412502091	0.443293702098478	HPGD	1
GO:0140327	flippase activity	1/240	16/18367	0.189849412502091	0.443293702098478	MFSD2A	1
GO:0005125	cytokine activity	5/240	235/18367	0.194649936164602	0.443975887752998	INHBA/EBI3/GDF15/INHA/MIF	5
GO:0000400	four-way junction DNA binding	1/240	17/18367	0.200444810082577	0.443975887752998	HMGB3	1
GO:0004697	protein kinase C activity	1/240	17/18367	0.200444810082577	0.443975887752998	PRKCZ	1
GO:0005324	long-chain fatty acid transporter activity	1/240	17/18367	0.200444810082577	0.443975887752998	MFSD2A	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/240	17/18367	0.200444810082577	0.443975887752998	BAD	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/240	17/18367	0.200444810082577	0.443975887752998	STEAP4	1
GO:0016854	racemase and epimerase activity	1/240	17/18367	0.200444810082577	0.443975887752998	GALE	1
GO:0017081	chloride channel regulator activity	1/240	17/18367	0.200444810082577	0.443975887752998	VAMP8	1
GO:0031489	myosin V binding	1/240	17/18367	0.200444810082577	0.443975887752998	RAB25	1
GO:0043024	ribosomal small subunit binding	1/240	17/18367	0.200444810082577	0.443975887752998	EIF4H	1
GO:0052745	inositol phosphate phosphatase activity	1/240	17/18367	0.200444810082577	0.443975887752998	IMPA2	1
GO:0004866	endopeptidase inhibitor activity	4/240	180/18367	0.209751778050459	0.452342291546292	TFPI2/TIMP2/TFPI/GAPDH	4
GO:0004303	estradiol 17-beta-dehydrogenase activity	1/240	18/18367	0.210902207661879	0.452342291546292	HSD17B1	1
GO:0008301	DNA binding, bending	1/240	18/18367	0.210902207661879	0.452342291546292	HMGB3	1
GO:0016755	aminoacyltransferase activity	1/240	18/18367	0.210902207661879	0.452342291546292	TGM2	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/240	18/18367	0.210902207661879	0.452342291546292	SASH1	1
GO:0050811	GABA receptor binding	1/240	18/18367	0.210902207661879	0.452342291546292	PLCL2	1
GO:0060229	lipase activator activity	1/240	18/18367	0.210902207661879	0.452342291546292	ARF1	1
GO:0043022	ribosome binding	2/240	66/18367	0.213361625963415	0.455555904084048	SBDS/SEC61B	2
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/240	19/18367	0.221223395201317	0.468753872404356	ENG	1
GO:0051536	iron-sulfur cluster binding	2/240	68/18367	0.222970689727138	0.468753872404356	FDX1/GLRX5	2
GO:0051540	metal cluster binding	2/240	68/18367	0.222970689727138	0.468753872404356	FDX1/GLRX5	2
GO:0003777	microtubule motor activity	2/240	69/18367	0.227788195313965	0.468753872404356	KIF2A/DYNLRB1	2
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/240	20/18367	0.231410139541391	0.468753872404356	CEBPB	1
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/240	20/18367	0.231410139541391	0.468753872404356	EDF1	1
GO:0016408	C-acyltransferase activity	1/240	20/18367	0.231410139541391	0.468753872404356	SPTLC3	1
GO:0016505	peptidase activator activity involved in apoptotic process	1/240	20/18367	0.231410139541391	0.468753872404356	BAD	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/240	20/18367	0.231410139541391	0.468753872404356	MAOA	1
GO:0019211	phosphatase activator activity	1/240	20/18367	0.231410139541391	0.468753872404356	CALM1	1
GO:0031681	G-protein beta-subunit binding	1/240	20/18367	0.231410139541391	0.468753872404356	GNG11	1
GO:0097001	ceramide binding	1/240	20/18367	0.231410139541391	0.468753872404356	MAP1LC3B	1
GO:0008237	metallopeptidase activity	4/240	190/18367	0.237410755592351	0.476262095027815	PAPPA2/PAPPA/MMP11/ADAM12	4
GO:0031491	nucleosome binding	2/240	71/18367	0.237443989365993	0.476262095027815	MBD2/SMARCB1	2
GO:0016298	lipase activity	3/240	129/18367	0.238131047513908	0.476262095027815	LGALS13/PLCL2/PRDX6	3
GO:0001848	complement binding	1/240	21/18367	0.241464184699186	0.478887127813448	CD59	1
GO:0008373	sialyltransferase activity	1/240	21/18367	0.241464184699186	0.478887127813448	ST3GAL4	1
GO:0033293	monocarboxylic acid binding	2/240	73/18367	0.247120901496397	0.485489464776108	STX3/GSTP1	2
GO:0061135	endopeptidase regulator activity	4/240	194/18367	0.248710510956391	0.485489464776108	TFPI2/TIMP2/TFPI/GAPDH	4
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/240	22/18367	0.251387252161968	0.485489464776108	RDH13	1
GO:0015645	fatty acid ligase activity	1/240	22/18367	0.251387252161968	0.485489464776108	ACSL4	1
GO:0017075	syntaxin-1 binding	1/240	22/18367	0.251387252161968	0.485489464776108	DAPK1	1
GO:0005254	chloride channel activity	2/240	74/18367	0.2519648962005	0.485489464776108	CLIC3/CLIC4	2
GO:0044325	transmembrane transporter binding	3/240	133/18367	0.252080704503056	0.485489464776108	CALM1/SRI/AP2M1	3
GO:0019902	phosphatase binding	4/240	196/18367	0.254404072493575	0.485489464776108	PDLIM4/CARHSP1/BAD/PPP1R11	4
GO:0002020	protease binding	3/240	135/18367	0.259100594004728	0.485489464776108	TIMP2/SRI/UBC	3
GO:0005212	structural constituent of eye lens	1/240	23/18367	0.26118104117702	0.485489464776108	CRYAB	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/240	23/18367	0.26118104117702	0.485489464776108	PRKCZ	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/240	23/18367	0.26118104117702	0.485489464776108	CDO1	1
GO:0030215	semaphorin receptor binding	1/240	23/18367	0.26118104117702	0.485489464776108	SEMA3B	1
GO:0050750	low-density lipoprotein particle receptor binding	1/240	23/18367	0.26118104117702	0.485489464776108	AP2M1	1
GO:0070412	R-SMAD binding	1/240	23/18367	0.26118104117702	0.485489464776108	RGCC	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/240	23/18367	0.26118104117702	0.485489464776108	SQSTM1	1
GO:0033218	amide binding	7/240	400/18367	0.269554340203393	0.490006055587408	INHBA/EBI3/CRYAB/CLTB/FKBP2/MAP1LC3B/AP2M1	7
GO:0004622	lysophospholipase activity	1/240	24/18367	0.270847229037765	0.490006055587408	LGALS13	1
GO:0010857	calcium-dependent protein kinase activity	1/240	24/18367	0.270847229037765	0.490006055587408	PRKCZ	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/240	24/18367	0.270847229037765	0.490006055587408	CDO1	1
GO:0016769	transferase activity, transferring nitrogenous groups	1/240	24/18367	0.270847229037765	0.490006055587408	GAPDH	1
GO:0043274	phospholipase binding	1/240	24/18367	0.270847229037765	0.490006055587408	PRKCZ	1
GO:0050431	transforming growth factor beta binding	1/240	24/18367	0.270847229037765	0.490006055587408	ENG	1
GO:0046332	SMAD binding	2/240	79/18367	0.276204505418465	0.495303455517853	DAB2/RGCC	2
GO:0005160	transforming growth factor beta receptor binding	1/240	25/18367	0.280387471366225	0.495303455517853	ENG	1
GO:0008327	methyl-CpG binding	1/240	25/18367	0.280387471366225	0.495303455517853	MBD2	1
GO:0034237	protein kinase A regulatory subunit binding	1/240	25/18367	0.280387471366225	0.495303455517853	EZR	1
GO:0035035	histone acetyltransferase binding	1/240	25/18367	0.280387471366225	0.495303455517853	CEBPB	1
GO:0070330	aromatase activity	1/240	25/18367	0.280387471366225	0.495303455517853	CYP19A1	1
GO:0030246	carbohydrate binding	5/240	271/18367	0.281089935726376	0.495303455517853	LGALS14/LGALS13/ENG/ALDOA/UGP2	5
GO:0004364	glutathione transferase activity	1/240	26/18367	0.289803402391855	0.504525996788288	GSTP1	1
GO:0004435	phosphatidylinositol phospholipase C activity	1/240	26/18367	0.289803402391855	0.504525996788288	PLCL2	1
GO:0008198	ferrous iron binding	1/240	26/18367	0.289803402391855	0.504525996788288	CDO1	1
GO:0005178	integrin binding	3/240	144/18367	0.290967477508245	0.504525996788288	TIMP2/FBLN1/EMP2	3
GO:0004683	calmodulin-dependent protein kinase activity	1/240	27/18367	0.299096635226812	0.504525996788288	DAPK1	1
GO:0016405	CoA-ligase activity	1/240	27/18367	0.299096635226812	0.504525996788288	ACSL4	1
GO:0016866	intramolecular transferase activity	1/240	27/18367	0.299096635226812	0.504525996788288	BPGM	1
GO:0035255	ionotropic glutamate receptor binding	1/240	27/18367	0.299096635226812	0.504525996788288	SQSTM1	1
GO:0045499	chemorepellent activity	1/240	27/18367	0.299096635226812	0.504525996788288	SEMA3B	1
GO:0048027	mRNA 5'-UTR binding	1/240	27/18367	0.299096635226812	0.504525996788288	RPS13	1
GO:0051959	dynein light intermediate chain binding	1/240	27/18367	0.299096635226812	0.504525996788288	DYNLL1	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/240	27/18367	0.299096635226812	0.504525996788288	MFSD2A	1
GO:0008013	beta-catenin binding	2/240	85/18367	0.305227420082391	0.508142980343707	SKP1/TAX1BP3	2
GO:0050660	flavin adenine dinucleotide binding	2/240	85/18367	0.305227420082391	0.508142980343707	STEAP4/MAOA	2
GO:0003785	actin monomer binding	1/240	28/18367	0.308268762137694	0.508142980343707	COBLL1	1
GO:0004629	phospholipase C activity	1/240	28/18367	0.308268762137694	0.508142980343707	PLCL2	1
GO:0070325	lipoprotein particle receptor binding	1/240	28/18367	0.308268762137694	0.508142980343707	AP2M1	1
GO:1990756	ubiquitin ligase-substrate adaptor activity	1/240	28/18367	0.308268762137694	0.508142980343707	SKP1	1
GO:0043021	ribonucleoprotein complex binding	3/240	149/18367	0.308799780992611	0.508142980343707	SBDS/EIF4H/SEC61B	3
GO:0019903	protein phosphatase binding	3/240	150/18367	0.31237206600192	0.508142980343707	PDLIM4/BAD/PPP1R11	3
GO:0003727	single-stranded RNA binding	2/240	87/18367	0.314860253025547	0.508142980343707	ANXA1/EIF4H	2
GO:0005253	anion channel activity	2/240	87/18367	0.314860253025547	0.508142980343707	CLIC3/CLIC4	2
GO:0051015	actin filament binding	4/240	217/18367	0.315489070997356	0.508142980343707	EZR/MARCKS/DSTN/GSN	4
GO:0004033	aldo-keto reductase (NADP) activity	1/240	29/18367	0.317321354813792	0.508142980343707	RDH13	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/240	29/18367	0.317321354813792	0.508142980343707	TECR	1
GO:0046625	sphingolipid binding	1/240	29/18367	0.317321354813792	0.508142980343707	MAP1LC3B	1
GO:0051059	NF-kappaB binding	1/240	29/18367	0.317321354813792	0.508142980343707	ANXA4	1
GO:0005184	neuropeptide hormone activity	1/240	30/18367	0.326255964631912	0.520691337493354	CRH	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/240	222/18367	0.330261277636035	0.524175360604084	SAT1/SPTLC3/PRDX6/TGM2	4
GO:0005085	guanyl-nucleotide exchange factor activity	4/240	223/18367	0.333221024235145	0.524175360604084	SH3BP5/RHOD/EPS8L1/NUCB2	4
GO:0008157	protein phosphatase 1 binding	1/240	31/18367	0.335074122917801	0.524175360604084	PPP1R11	1
GO:0016878	acid-thiol ligase activity	1/240	31/18367	0.335074122917801	0.524175360604084	ACSL4	1
GO:0031210	phosphatidylcholine binding	1/240	31/18367	0.335074122917801	0.524175360604084	CHMP2A	1
GO:0043015	gamma-tubulin binding	1/240	31/18367	0.335074122917801	0.524175360604084	NDRG1	1
GO:0001223	transcription coactivator binding	1/240	32/18367	0.343777341204217	0.534263802396062	EPAS1	1
GO:0015605	organophosphate ester transmembrane transporter activity	1/240	32/18367	0.343777341204217	0.534263802396062	MFSD2A	1
GO:0016410	N-acyltransferase activity	2/240	94/18367	0.348309612702334	0.539538419676164	SAT1/TGM2	2
GO:0004623	phospholipase A2 activity	1/240	33/18367	0.3523671114857	0.542796622261926	PRDX6	1
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	5/240	299/18367	0.352703290414923	0.542796622261926	HSPB1/ANXA4/CEBPB/HES1/SMARCB1	5
GO:0004867	serine-type endopeptidase inhibitor activity	2/240	98/18367	0.36718400164828	0.563253128742022	TFPI2/TFPI	2
GO:0000217	DNA secondary structure binding	1/240	36/18367	0.377470366431635	0.577164366737403	HMGB3	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	5/240	310/18367	0.38119689826056	0.578766268116864	HES2/CEBPB/HES1/TFAP2A/ATF3	5
GO:0016409	palmitoyltransferase activity	1/240	37/18367	0.385620882609498	0.578766268116864	SPTLC3	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/240	37/18367	0.385620882609498	0.578766268116864	GAPDH	1
GO:0043531	ADP binding	1/240	37/18367	0.385620882609498	0.578766268116864	PRKAG2	1
GO:0071949	FAD binding	1/240	37/18367	0.385620882609498	0.578766268116864	STEAP4	1
GO:0004497	monooxygenase activity	2/240	102/18367	0.385844178744576	0.578766268116864	CYP11A1/CYP19A1	2
GO:0001217	DNA-binding transcription repressor activity	5/240	313/18367	0.388968102032595	0.5805738708991	HES2/CEBPB/HES1/TFAP2A/ATF3	5
GO:0031490	chromatin DNA binding	2/240	103/18367	0.390472441136821	0.5805738708991	MBD2/SMARCB1	2
GO:0005201	extracellular matrix structural constituent	3/240	172/18367	0.390723765436314	0.5805738708991	TFPI2/MFAP5/FBLN1	3
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/240	38/18367	0.393665126372385	0.58129990623212	FKBP2	1
GO:0140303	intramembrane lipid transporter activity	1/240	38/18367	0.393665126372385	0.58129990623212	MFSD2A	1
GO:0004252	serine-type endopeptidase activity	3/240	174/18367	0.397768199060829	0.584281065354211	MMP11/HTRA1/HTRA4	3
GO:0005096	GTPase activator activity	7/240	462/18367	0.399704016941184	0.584281065354211	SYDE1/DEPDC1B/SH3BP5/RHOD/EPS8L1/NUCB2/RASA1	7
GO:0019825	oxygen binding	1/240	39/18367	0.401604477655632	0.584281065354211	CYP19A1	1
GO:0050997	quaternary ammonium group binding	1/240	39/18367	0.401604477655632	0.584281065354211	CHMP2A	1
GO:0003925	G protein activity	1/240	40/18367	0.409440298550582	0.584281065354211	RAB1A	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/240	40/18367	0.409440298550582	0.584281065354211	CYP19A1	1
GO:0042169	SH2 domain binding	1/240	40/18367	0.409440298550582	0.584281065354211	SQSTM1	1
GO:0043014	alpha-tubulin binding	1/240	40/18367	0.409440298550582	0.584281065354211	BEX4	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/240	40/18367	0.409440298550582	0.584281065354211	BAD	1
GO:0044183	protein folding chaperone	1/240	40/18367	0.409440298550582	0.584281065354211	HSPB1	1
GO:0042277	peptide binding	5/240	321/18367	0.409656114889175	0.584281065354211	INHBA/EBI3/CRYAB/CLTB/AP2M1	5
GO:0140297	DNA-binding transcription factor binding	6/240	394/18367	0.410475938318465	0.584281065354211	HSPB1/ANXA4/SRI/CEBPB/HES1/SMARCB1	6
GO:0016746	acyltransferase activity	4/240	250/18367	0.413073796045115	0.586218500974204	SAT1/SPTLC3/PRDX6/TGM2	4
GO:0016859	cis-trans isomerase activity	1/240	41/18367	0.417173933534369	0.587792228808657	FKBP2	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/240	41/18367	0.417173933534369	0.587792228808657	ACSL4	1
GO:0042626	ATPase-coupled transmembrane transporter activity	2/240	109/18367	0.417902913731049	0.587792228808657	ATP6V1F/ATP6V1G1	2
GO:0015399	primary active transmembrane transporter activity	3/240	181/18367	0.422240159497046	0.59049378415325	ATP6V1F/ATP6V1G1/NDUFA6	3
GO:0008047	enzyme activator activity	2/240	110/18367	0.42241483987407	0.59049378415325	CALM1/ARF1	2
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/240	42/18367	0.424806709696747	0.59049378415325	NDUFA6	1
GO:0019205	nucleobase-containing compound kinase activity	1/240	42/18367	0.424806709696747	0.59049378415325	UCK2	1
GO:0050136	NADH dehydrogenase (quinone) activity	1/240	43/18367	0.43233993696402	0.599207982809783	NDUFA6	1
GO:0001784	phosphotyrosine residue binding	1/240	44/18367	0.439774908320091	0.604906359488615	RASA1	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/240	44/18367	0.439774908320091	0.604906359488615	GAPDH	1
GO:0003774	cytoskeletal motor activity	2/240	114/18367	0.44027994519741	0.604906359488615	KIF2A/DYNLRB1	2
GO:0003954	NADH dehydrogenase activity	1/240	45/18367	0.44711290002468	0.610753644414116	NDUFA6	1
GO:0003955	NAD(P)H dehydrogenase (quinone) activity	1/240	45/18367	0.44711290002468	0.610753644414116	NDUFA6	1
GO:0061980	regulatory RNA binding	1/240	46/18367	0.454355171828744	0.613990677609518	MBD2	1
GO:0140296	general transcription initiation factor binding	1/240	46/18367	0.454355171828744	0.613990677609518	EDF1	1
GO:0030695	GTPase regulator activity	7/240	488/18367	0.455137576913256	0.613990677609518	SYDE1/DEPDC1B/SH3BP5/RHOD/EPS8L1/NUCB2/RASA1	7
GO:0060589	nucleoside-triphosphatase regulator activity	7/240	488/18367	0.455137576913256	0.613990677609518	SYDE1/DEPDC1B/SH3BP5/RHOD/EPS8L1/NUCB2/RASA1	7
GO:0008236	serine-type peptidase activity	3/240	191/18367	0.456592501163688	0.613990677609518	MMP11/HTRA1/HTRA4	3
GO:0003712	transcription coregulator activity	7/240	489/18367	0.457254660751392	0.613990677609518	BASP1/RYBP/SMARCB1/SAP18/TCF25/EDF1/TFAP2A	7
GO:0015026	coreceptor activity	1/240	48/18367	0.468557513468528	0.625623271504457	ENG	1
GO:0070888	E-box binding	1/240	48/18367	0.468557513468528	0.625623271504457	HES1	1
GO:0017171	serine hydrolase activity	3/240	195/18367	0.470096482036613	0.625914978891445	MMP11/HTRA1/HTRA4	3
GO:0051082	unfolded protein binding	2/240	122/18367	0.475078000144894	0.62959913548909	CRYAB/NACA	2
GO:0016763	pentosyltransferase activity	1/240	49/18367	0.475520022162646	0.62959913548909	UPP1	1
GO:0005048	signal sequence binding	1/240	50/18367	0.482391689084852	0.636918274724846	AP2M1	1
GO:0003743	translation initiation factor activity	1/240	51/18367	0.48917369457809	0.643465771375669	EIF4H	1
GO:0005516	calmodulin binding	3/240	201/18367	0.490065703516069	0.643465771375669	MARCKS/DAPK1/EDF1	3
GO:0004175	endopeptidase activity	6/240	430/18367	0.493233927357136	0.64571718285606	PAPPA2/PAPPA/MMP11/ADAM12/HTRA1/HTRA4	6
GO:0016830	carbon-carbon lyase activity	1/240	52/18367	0.495867203712249	0.64571718285606	ALDOA	1
GO:0031593	polyubiquitin modification-dependent protein binding	1/240	52/18367	0.495867203712249	0.64571718285606	SQSTM1	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/240	53/18367	0.502473366480966	0.652527056745145	MFSD2A	1
GO:0106310	protein serine kinase activity	5/240	360/18367	0.508276016673149	0.653828814986608	PRKCZ/STK3/CSNK2A2/DAPK1/PIM3	5
GO:0015078	proton transmembrane transporter activity	2/240	130/18367	0.508540402336698	0.653828814986608	ATP6V1F/ATP6V1G1	2
GO:0017124	SH3 domain binding	2/240	130/18367	0.508540402336698	0.653828814986608	ADAM12/SH3BP5	2
GO:0008374	O-acyltransferase activity	1/240	54/18367	0.508993317995904	0.653828814986608	PRDX6	1
GO:0030170	pyridoxal phosphate binding	1/240	55/18367	0.515428178678533	0.660133941995567	SPTLC3	1
GO:0016779	nucleotidyltransferase activity	2/240	132/18367	0.516687114937459	0.660133941995567	UGP2/NANS	2
GO:0045309	protein phosphorylated amino acid binding	1/240	56/18367	0.521779054449456	0.663065071874108	RASA1	1
GO:0070279	vitamin B6 binding	1/240	56/18367	0.521779054449456	0.663065071874108	SPTLC3	1
GO:0005548	phospholipid transporter activity	1/240	57/18367	0.528047036915303	0.667451454660943	MFSD2A	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/240	57/18367	0.528047036915303	0.667451454660943	NDUFA6	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/240	58/18367	0.534233203553224	0.673474836394224	MFSD2A	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	6/240	450/18367	0.537598598117681	0.675919722832309	MAFF/CEBPB/EPAS1/TFAP2A/ATF3/GCM1	6
GO:0001664	G protein-coupled receptor binding	4/240	295/18367	0.540173616199949	0.677360566345968	KISS1/CRH/CALM1/NPB	4
GO:0019955	cytokine binding	2/240	139/18367	0.544489261848318	0.679728851118988	EBI3/ENG	2
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/240	60/18367	0.546364329696908	0.679728851118988	TECR	1
GO:0032934	sterol binding	1/240	60/18367	0.546364329696908	0.679728851118988	INSIG1	1
GO:0001216	DNA-binding transcription activator activity	6/240	456/18367	0.550591177441443	0.683194288238859	MAFF/CEBPB/EPAS1/TFAP2A/ATF3/GCM1	6
GO:0019787	ubiquitin-like protein transferase activity	6/240	458/18367	0.554885931268073	0.686725669506702	UBE2A/RBX1/RNF7/UBE2B/PPP1R11/UFC1	6
GO:0019199	transmembrane receptor protein kinase activity	2/240	143/18367	0.559871042071931	0.69109081755754	ENG/FLT1	2
GO:0005543	phospholipid binding	6/240	466/18367	0.57187516579031	0.704074879440538	ANXA4/ANXA1/GSN/BAD/CHMP2A/SNX9	6
GO:0052689	carboxylic ester hydrolase activity	2/240	147/18367	0.574880433015749	0.705941257122966	LGALS13/PRDX6	2
GO:0002039	p53 binding	1/240	66/18367	0.58090194348862	0.711492302877535	SMARCB1	1
GO:0140677	molecular function activator activity	2/240	150/18367	0.585891617163264	0.715754192101514	CALM1/ARF1	2
GO:0008080	N-acetyltransferase activity	1/240	68/18367	0.591822299490172	0.720862835260466	SAT1	1
GO:0015103	inorganic anion transmembrane transporter activity	2/240	152/18367	0.593114991037092	0.720862835260466	CLIC3/CLIC4	2
GO:0001098	basal transcription machinery binding	1/240	70/18367	0.602459260718283	0.728483901990985	EDF1	1
GO:0001099	basal RNA polymerase II transcription machinery binding	1/240	70/18367	0.602459260718283	0.728483901990985	EDF1	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/240	71/18367	0.607673764594744	0.732919502335646	TGM2	1
GO:0003678	DNA helicase activity	1/240	72/18367	0.612820151591752	0.735384181910103	ANXA1	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/240	72/18367	0.612820151591752	0.735384181910103	NDUFA6	1
GO:0015370	solute:sodium symporter activity	1/240	73/18367	0.617899307843077	0.737743757978888	MFSD2A	1
GO:0140104	molecular carrier activity	1/240	73/18367	0.617899307843077	0.737743757978888	COX17	1
GO:0003725	double-stranded RNA binding	1/240	74/18367	0.622912108002564	0.741206013330417	EIF4H	1
GO:0046982	protein heterodimerization activity	4/240	328/18367	0.623926580841427	0.741206013330417	SRI/CEBPB/EPAS1/ATF3	4
GO:0038024	cargo receptor activity	1/240	77/18367	0.637560949366517	0.755509724999323	DAB2	1
GO:0001221	transcription coregulator binding	1/240	78/18367	0.642316847242517	0.757358670629236	EPAS1	1
GO:0030971	receptor tyrosine kinase binding	1/240	78/18367	0.642316847242517	0.757358670629236	SQSTM1	1
GO:0016835	carbon-oxygen lyase activity	1/240	79/18367	0.64701059521462	0.761000054917444	TPI1	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/240	170/18367	0.653905790507037	0.767206298763207	CYP11A1/CYP19A1	2
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/240	82/18367	0.660726975618681	0.77329527516853	GSN	1
GO:0001540	amyloid-beta binding	1/240	84/18367	0.669575031120525	0.777476424702042	CRYAB	1
GO:0008135	translation factor activity, RNA binding	1/240	84/18367	0.669575031120525	0.777476424702042	EIF4H	1
GO:0030165	PDZ domain binding	1/240	84/18367	0.669575031120525	0.777476424702042	GIPC1	1
GO:0004842	ubiquitin-protein transferase activity	5/240	433/18367	0.67112867344106	0.777476424702042	UBE2A/RBX1/RNF7/UBE2B/PPP1R11	5
GO:0031406	carboxylic acid binding	2/240	176/18367	0.672500704911049	0.777476424702042	STX3/GSTP1	2
GO:0022853	active ion transmembrane transporter activity	3/240	267/18367	0.680926348347629	0.785301919992156	MFSD2A/ATP6V1F/ATP6V1G1	3
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/240	88/18367	0.686587638923196	0.787002581039013	NDUFA6	1
GO:0051219	phosphoprotein binding	1/240	88/18367	0.686587638923196	0.787002581039013	RASA1	1
GO:0003735	structural constituent of ribosome	2/240	182/18367	0.690280605914359	0.787002581039013	RPS13/RPS4Y1	2
GO:0008081	phosphoric diester hydrolase activity	1/240	89/18367	0.690702687156602	0.787002581039013	PLCL2	1
GO:0043178	alcohol binding	1/240	89/18367	0.690702687156602	0.787002581039013	PLCL2	1
GO:0016407	acetyltransferase activity	1/240	91/18367	0.698772061298321	0.794287666799531	SAT1	1
GO:0051213	dioxygenase activity	1/240	92/18367	0.702727779469059	0.796873127914675	CDO1	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/240	94/18367	0.710484691222198	0.803746404867116	MAN1C1	1
GO:0004896	cytokine receptor activity	1/240	97/18367	0.72174372346845	0.81453934505725	EBI3	1
GO:0016829	lyase activity	2/240	196/18367	0.728691929984815	0.820427493617107	TPI1/ALDOA	2
GO:0051020	GTPase binding	3/240	291/18367	0.735726047106281	0.826384233005633	NDRG1/RHOBTB3/RASA1	3
GO:0005244	voltage-gated ion channel activity	2/240	201/18367	0.741402546664851	0.828630412429762	CLIC3/CLIC4	2
GO:0022832	voltage-gated channel activity	2/240	201/18367	0.741402546664851	0.828630412429762	CLIC3/CLIC4	2
GO:0005200	structural constituent of cytoskeleton	1/240	103/18367	0.742970306503479	0.828630412429762	KRT19	1
GO:0015294	solute:cation symporter activity	1/240	104/18367	0.746347832042198	0.83044336241315	MFSD2A	1
GO:1990782	protein tyrosine kinase binding	1/240	105/18367	0.749681157361689	0.832198755478784	SQSTM1	1
GO:0051087	chaperone binding	1/240	107/18367	0.756217504028983	0.835541018437618	HES1	1
GO:1902936	phosphatidylinositol bisphosphate binding	1/240	107/18367	0.756217504028983	0.835541018437618	GSN	1
GO:0090079	translation regulator activity, nucleic acid binding	1/240	108/18367	0.759421655126083	0.837129917511078	EIF4H	1
GO:0061630	ubiquitin protein ligase activity	3/240	304/18367	0.762174886443129	0.83821553636669	RBX1/RNF7/PPP1R11	3
GO:0008094	ATP-dependent activity, acting on DNA	1/240	111/18367	0.768784644991795	0.84352759658822	ANXA1	1
GO:0022804	active transmembrane transporter activity	4/240	406/18367	0.780270319780757	0.853019626801778	MFSD2A/ATP6V1F/ATP6V1G1/NDUFA6	4
GO:0008509	anion transmembrane transporter activity	3/240	314/18367	0.781034848168716	0.853019626801778	MFSD2A/CLIC3/CLIC4	3
GO:0061659	ubiquitin-like protein ligase activity	3/240	316/18367	0.784656086801458	0.855004563549175	RBX1/RNF7/PPP1R11	3
GO:0003697	single-stranded DNA binding	1/240	123/18367	0.802744691058747	0.871686043540545	ANXA1	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/240	124/18367	0.805339586594041	0.871686043540545	FLT1	1
GO:0005539	glycosaminoglycan binding	2/240	230/18367	0.805482040233668	0.871686043540545	PGF/ENG	2
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/240	125/18367	0.807900486622404	0.872311687150386	TGM2	1
GO:0043177	organic acid binding	1/240	135/18367	0.831734516944748	0.896004911435933	STX3	1
GO:0004713	protein tyrosine kinase activity	1/240	136/18367	0.833949507945914	0.896353892894247	FLT1	1
GO:0045182	translation regulator activity	1/240	140/18367	0.842522863232319	0.902037181399074	EIF4H	1
GO:0070851	growth factor receptor binding	1/240	141/18367	0.844596408677221	0.902037181399074	PGF	1
GO:0015293	symporter activity	1/240	144/18367	0.850655316635836	0.902037181399074	MFSD2A	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	1/240	144/18367	0.850655316635836	0.902037181399074	MAN1C1	1
GO:0016922	nuclear receptor binding	1/240	144/18367	0.850655316635836	0.902037181399074	CEBPB	1
GO:0140375	immune receptor activity	1/240	144/18367	0.850655316635836	0.902037181399074	EBI3	1
GO:0031267	small GTPase binding	2/240	259/18367	0.855088077905645	0.903859275836739	NDRG1/RHOBTB3	2
GO:0019842	vitamin binding	1/240	148/18367	0.858369452422438	0.903859275836739	SPTLC3	1
GO:0003713	transcription coactivator activity	2/240	262/18367	0.859503317108304	0.903859275836739	SMARCB1/EDF1	2
GO:0042578	phosphoric ester hydrolase activity	3/240	366/18367	0.860196046643993	0.903859275836739	ALPP/PLCL2/IMPA2	3
GO:1901681	sulfur compound binding	2/240	265/18367	0.863795677082439	0.903859275836739	PGF/GSTP1	2
GO:0015081	sodium ion transmembrane transporter activity	1/240	152/18367	0.865686702638511	0.903859275836739	MFSD2A	1
GO:0005319	lipid transporter activity	1/240	154/18367	0.869202892582115	0.903859275836739	MFSD2A	1
GO:0016757	glycosyltransferase activity	2/240	270/18367	0.870684267937396	0.903859275836739	UPP1/ST3GAL4	2
GO:0035091	phosphatidylinositol binding	2/240	271/18367	0.872023120611346	0.903859275836739	GSN/SNX9	2
GO:0004386	helicase activity	1/240	156/18367	0.872627405660202	0.903859275836739	ANXA1	1
GO:0016887	ATP hydrolysis activity	2/240	272/18367	0.873349258086976	0.903859275836739	RHOBTB3/KIF2A	2
GO:0016791	phosphatase activity	2/240	275/18367	0.877252395966099	0.90592077491924	ALPP/IMPA2	2
GO:0140030	modification-dependent protein binding	1/240	160/18367	0.879210861779581	0.905969453225047	SQSTM1	1
GO:0046943	carboxylic acid transmembrane transporter activity	1/240	163/18367	0.88392506381235	0.907603773941025	MFSD2A	1
GO:0005342	organic acid transmembrane transporter activity	1/240	164/18367	0.885455385976986	0.907603773941025	MFSD2A	1
GO:0016874	ligase activity	1/240	165/18367	0.886965615464737	0.907603773941025	ACSL4	1
GO:0008201	heparin binding	1/240	166/18367	0.888456014997121	0.907603773941025	PGF	1
GO:1901981	phosphatidylinositol phosphate binding	1/240	173/18367	0.898354934237623	0.915742449093835	GSN	1
GO:0008514	organic anion transmembrane transporter activity	1/240	185/18367	0.913331436506372	0.929010946145966	MFSD2A	1
GO:0003730	mRNA 3'-UTR binding	1/240	201/18367	0.929936727584155	0.943875822001905	CARHSP1	1
GO:0022836	gated channel activity	2/240	340/18367	0.938798927450238	0.950834811135498	CLIC3/CLIC4	2
GO:0140097	catalytic activity, acting on DNA	1/240	229/18367	0.951733744367264	0.961880159552416	ANXA1	1
GO:0015291	secondary active transmembrane transporter activity	1/240	240/18367	0.958313818897687	0.966469681186178	MFSD2A	1
GO:0005216	ion channel activity	2/240	432/18367	0.978175957246119	0.984406377355967	CLIC3/CLIC4	2
GO:0015267	channel activity	2/240	480/18367	0.98746492853128	0.989698138761994	CLIC3/CLIC4	2
GO:0022803	passive transmembrane transporter activity	2/240	481/18367	0.987610168005112	0.989698138761994	CLIC3/CLIC4	2
GO:0046873	metal ion transmembrane transporter activity	1/240	430/18367	0.996731276876991	0.996731276876991	MFSD2A	1