ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0042608	T cell receptor binding	6/388	11/18367	3.61277832934231e-08	1.91858574526956e-05	HLA-A/CD3E/HLA-E/CD3G/FYN/LCK	6
GO:0003779	actin binding	29/388	440/18367	6.87665141673678e-08	1.91858574526956e-05	TMSB4X/LCP1/CORO1A/SYNE1/S100A4/EVL/MSN/GMFG/CXCR4/WIPF1/LSP1/PPP1R18/TPM3/FXYD5/CNN2/RCSD1/WAS/FLNA/CFL1/TMSB10/EPB41/FMNL1/PFN1/MYO1F/TLN1/ACTR3/ARPC5L/MACF1/ACTR2	29
GO:0048020	CCR chemokine receptor binding	9/388	48/18367	6.18305709174144e-07	0.000101531157048288	CCL4/CCL5/XCL2/XCL1/JAK1/CCL3/STAT1/CCL3L3/STAT3	9
GO:0003823	antigen binding	16/388	171/18367	7.27821914324645e-07	0.000101531157048288	KLRD1/IL7R/TRDC/HLA-A/HLA-B/HLA-C/TRBC1/HLA-E/TRBC2/CD48/HLA-F/SPON2/ITGA4/TGFB1/TAP1/TAPBP	16
GO:0003735	structural constituent of ribosome	16/388	182/18367	1.67193362792201e-06	0.000186587792876096	RPL10/RPL28/RPS15A/RPL41/RPL13/RPS4X/RPS27/ISG15/RPS27A/RPL39/RPL30/RPL35A/RPS29/RPL19/RPL3/RPL17	16
GO:0042379	chemokine receptor binding	10/388	72/18367	2.63380584497827e-06	0.000244943943582979	CCL4/CCL5/XCL2/XCL1/JAK1/CCL3/STAT1/CCL3L3/CKLF/STAT3	10
GO:0042605	peptide antigen binding	7/388	36/18367	8.75022741259003e-06	0.000697518128032177	HLA-A/HLA-B/HLA-C/HLA-E/HLA-F/TAP1/TAPBP	7
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/388	45/18367	4.03938263664725e-05	0.00281746938906146	FYN/LCK/MATK/TXK/JAK1/CSK/CLK1	7
GO:0005126	cytokine receptor binding	17/388	271/18367	6.85760749378405e-05	0.00360741019562154	CCL4/CCL5/XCL2/XCL1/LTB/JAK1/TNF/CCL3/TGFB1/CASP8/STAT1/CCL3L3/PIK3R1/CKLF/PYCARD/STAT3/CFLAR	17
GO:0043548	phosphatidylinositol 3-kinase binding	6/388	34/18367	6.96868159570099e-05	0.00360741019562154	HCST/CORO1A/FYN/LCK/CALM1/PIK3R1	6
GO:0008009	chemokine activity	7/388	49/18367	7.11138210606397e-05	0.00360741019562154	CCL4/CCL5/XCL2/XCL1/CCL3/CCL3L3/CKLF	7
GO:0017124	SH3 domain binding	11/388	130/18367	9.97250312144477e-05	0.00463721395147182	CD3E/SKAP1/PTPN22/EVL/CYBA/WIPF1/WAS/SH3BGRL/CBLB/SH3KBP1/PTPN6	11
GO:0051015	actin filament binding	14/388	217/18367	0.000221890753742705	0.00952423389141763	LCP1/CORO1A/SYNE1/TPM3/RCSD1/FLNA/CFL1/FMNL1/MYO1F/TLN1/ACTR3/ARPC5L/MACF1/ACTR2	14
GO:0016004	phospholipase activator activity	4/388	16/18367	0.000291780615655664	0.0115086711226073	CCL5/FYN/LCK/CCL3	4
GO:0035591	signaling adaptor activity	8/388	81/18367	0.000309372879639982	0.0115086711226073	CD3E/CD3G/LAT/DOK2/CDC42SE2/PIK3R1/AKAP13/STAT3	8
GO:0005200	structural constituent of cytoskeleton	9/388	103/18367	0.00033354759550091	0.0116324723930942	MSN/VIM/EPB41/ACTB/TLN1/TUBA1A/ACTR3/ACTR2/ACTG1	9
GO:0060229	lipase activator activity	4/388	18/18367	0.000474436621978222	0.0155726844155205	CCL5/FYN/LCK/CCL3	4
GO:0140375	immune receptor activity	10/388	144/18367	0.000984630114305019	0.0295200515102952	KLRD1/IL7R/IL2RG/KLRC1/KLRF1/IL2RB/CXCR4/CD44/FCER1G/IL10RA	10
GO:0005522	profilin binding	3/388	10/18367	0.00100516304425736	0.0295200515102952	EVL/WIPF1/ACTG1	3
GO:0044389	ubiquitin-like protein ligase binding	16/388	316/18367	0.0011835932301489	0.0330222511211542	PYHIN1/TXNIP/PTPN22/JAK1/CXCR4/PRKACB/CASP8/JUN/STAT1/LAPTM5/YWHAZ/ISG15/RPS27A/UBE2L6/ACTG1/NFKBIA	16
GO:0042287	MHC protein binding	5/388	40/18367	0.00146845352365476	0.0383248552094919	KLRD1/HLA-E/TAP1/TAPBP/CD81	5
GO:0001664	G protein-coupled receptor binding	15/388	295/18367	0.00160053994568701	0.0383248552094919	CCL4/CCL5/XCL2/XCL1/FYN/JAK1/CALM1/CCL3/ARHGEF1/FLNA/STAT1/CCL3L3/CKLF/SLC9A3R1/STAT3	15
GO:0031625	ubiquitin protein ligase binding	15/388	297/18367	0.00170969213425272	0.0383248552094919	PYHIN1/TXNIP/PTPN22/JAK1/CXCR4/PRKACB/CASP8/JUN/LAPTM5/YWHAZ/ISG15/RPS27A/UBE2L6/ACTG1/NFKBIA	15
GO:0030695	GTPase regulator activity	21/388	488/18367	0.00172868475298888	0.0383248552094919	ARHGDIB/ACAP1/RASGRP1/TBC1D10C/DENND2D/ARAP2/ARHGAP30/TAGAP/GPSM3/ARHGEF1/RGS1/WAS/CYTH1/JUN/SMAP2/EEF1D/ARHGEF3/EEF1B2/CDC42SE1/AKAP13/RASA2	21
GO:0060589	nucleoside-triphosphatase regulator activity	21/388	488/18367	0.00172868475298888	0.0383248552094919	ARHGDIB/ACAP1/RASGRP1/TBC1D10C/DENND2D/ARAP2/ARHGAP30/TAGAP/GPSM3/ARHGEF1/RGS1/WAS/CYTH1/JUN/SMAP2/EEF1D/ARHGEF3/EEF1B2/CDC42SE1/AKAP13/RASA2	21
GO:0035256	G protein-coupled glutamate receptor binding	3/388	12/18367	0.00178574594166091	0.0383248552094919	FYN/CALM1/SLC9A3R1	3
GO:0001784	phosphotyrosine residue binding	5/388	44/18367	0.00226232464632743	0.0447188728953241	LCK/PFN1/PIK3R1/CBLB/PTPN6	5
GO:0072542	protein phosphatase activator activity	3/388	13/18367	0.00228530849705886	0.0447188728953241	CALM1/PPP2R5C/PPP1R15A	3
GO:0008047	enzyme activator activity	8/388	110/18367	0.00232409912896846	0.0447188728953241	CCL5/FYN/LCK/ALOX5AP/GMFG/CALM1/CCL3/CFLAR	8
GO:0003785	actin monomer binding	4/388	28/18367	0.00268752701949846	0.0499880025626713	TMSB4X/CORO1A/TMSB10/PFN1	4
GO:0019902	phosphatase binding	11/388	196/18367	0.0030905326639645	0.055629587951361	SKAP1/LCK/JAK1/PPP1R18/STAT1/PIK3R1/CSK/TERF2IP/SLC9A3R1/PPP1R15A/STAT3	11
GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	3/388	15/18367	0.00352351279347707	0.0593901877995594	CASP8/PYCARD/CFLAR	3
GO:0031267	small GTPase binding	13/388	259/18367	0.0035774256322925	0.0593901877995594	ARHGDIB/RASSF5/WAS/FLNA/RAB29/FMNL1/PFN1/CDC42SE2/CDC42SE1/SORL1/AKAP13/GCC2/ROCK1	13
GO:0032813	tumor necrosis factor receptor superfamily binding	5/388	49/18367	0.00364548133358913	0.0593901877995594	LTB/TNF/CASP8/STAT1/CFLAR	5
GO:0051020	GTPase binding	14/388	291/18367	0.00372519099101179	0.0593901877995594	LCP1/ARHGDIB/RASSF5/WAS/FLNA/RAB29/FMNL1/PFN1/CDC42SE2/CDC42SE1/SORL1/AKAP13/GCC2/ROCK1	14
GO:0005164	tumor necrosis factor receptor binding	4/388	31/18367	0.00392972569860606	0.0600480759169008	LTB/TNF/CASP8/STAT1	4
GO:0030159	signaling receptor complex adaptor activity	5/388	50/18367	0.0039816824532712	0.0600480759169008	CD3E/CD3G/LAT/DOK2/PIK3R1	5
GO:0005125	cytokine activity	12/388	235/18367	0.00439397655453327	0.0614169227671787	CCL4/CCL5/IL32/XCL2/XCL1/LTB/TNF/CCL3/TGFB1/CCL3L3/CMTM3/CKLF	12
GO:0071889	14-3-3 protein binding	4/388	32/18367	0.00441740173343745	0.0614169227671787	HLA-F/DDIT4/ZFP36/PPP1R12A	4
GO:0140297	DNA-binding transcription factor binding	17/388	394/18367	0.00448125909538873	0.0614169227671787	EOMES/DDX5/PTMA/MTDH/NR4A2/JUN/ACTB/STAT1/FOS/ID2/JUND/YWHAZ/LYAR/COMMD6/STAT3/PRMT2/NFKBIA	17
GO:0140677	molecular function activator activity	9/388	150/18367	0.00465262313751291	0.0614169227671787	CCL5/FYN/LCK/ALOX5AP/GMFG/CALM1/CCL3/CFLAR/DNAJC1	9
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	14/388	299/18367	0.00472574111556723	0.0614169227671787	EOMES/DDX5/MTDH/NR4A2/JUN/ACTB/STAT1/FOS/ID2/JUND/COMMD6/STAT3/PRMT2/NFKBIA	14
GO:0017022	myosin binding	6/388	74/18367	0.0047328453028471	0.0614169227671787	CORO1A/CXCR4/RAB27A/VAMP2/SLC9A3R1/PYCARD	6
GO:0019956	chemokine binding	4/388	33/18367	0.00494425675923184	0.0627021652648038	CXCR4/ITGA4/PLP2/ZFP36	4
GO:0070064	proline-rich region binding	3/388	17/18367	0.00510374051916377	0.0632863824376308	PFN1/CYLD/CSK	3
GO:0004725	protein tyrosine phosphatase activity	7/388	102/18367	0.00589894804358545	0.0715568045287105	PTPRC/DUSP2/PTPN22/PTPN4/DUSP1/PTPN6/PTP4A2	7
GO:0045309	protein phosphorylated amino acid binding	5/388	56/18367	0.00647801240710713	0.0769091685779953	LCK/PFN1/PIK3R1/CBLB/PTPN6	5
GO:0005525	GTP binding	16/388	377/18367	0.00668787029493687	0.0771335275371352	GIMAP7/RAC2/GIMAP4/GBP5/ARL4C/GIMAP1/GBP4/RAB29/RAB27A/GBP2/RAB8B/IFI44L/TUBA1A/RAP1B/SAMHD1/CDC42	16
GO:0023023	MHC protein complex binding	4/388	36/18367	0.00677337428193481	0.0771335275371352	KLRD1/KLRC1/B2M/CD81	4
GO:0019208	phosphatase regulator activity	7/388	107/18367	0.007620663858256	0.0850466086581369	CALM1/PPP2R5C/ZEB2/PPP1R15A/ANP32E/PPP1R2/PPP1R12A	7
GO:0019211	phosphatase activator activity	3/388	20/18367	0.00816513299561057	0.0876181579144365	CALM1/PPP2R5C/PPP1R15A	3
GO:0042288	MHC class I protein binding	3/388	20/18367	0.00816513299561057	0.0876181579144365	HLA-E/TAP1/TAPBP	3
GO:0042277	peptide binding	14/388	321/18367	0.00863370805140404	0.0908982847676124	HLA-A/HLA-B/HLA-C/HLA-E/CRIP1/HLA-F/ITM2A/ITGB2/TAP1/PIK3R1/SORL1/TAPBP/LNPEP/NFKBIA	14
GO:0043621	protein self-association	5/388	61/18367	0.00926440987610534	0.0957322353864218	CCL5/CD2/TNFAIP3/VAMP2/SLC9A3R1	5
GO:0005096	GTPase activator activity	18/388	462/18367	0.00973219077877667	0.0987157893492137	ARHGDIB/ACAP1/RASGRP1/TBC1D10C/DENND2D/ARAP2/ARHGAP30/TAGAP/ARHGEF1/RGS1/CYTH1/JUN/SMAP2/EEF1D/ARHGEF3/EEF1B2/AKAP13/RASA2	18
GO:1990841	promoter-specific chromatin binding	5/388	62/18367	0.00990696093827234	0.0987157893492137	IKZF3/PRDM1/DDX5/RBL2/STAT1	5
GO:0030674	protein-macromolecule adaptor activity	13/388	296/18367	0.0105690479742624	0.100052323960216	CD3E/CD3G/SYNE1/LAT/DOK2/TRIM22/SUN2/CDC42SE2/PIK3R1/VAMP2/SLC9A3R1/AKAP13/STAT3	13
GO:0051219	phosphoprotein binding	6/388	88/18367	0.0108409902391066	0.100052323960216	LCK/EPB41/PFN1/PIK3R1/CBLB/PTPN6	6
GO:0019001	guanyl nucleotide binding	16/388	398/18367	0.0108994614193753	0.100052323960216	GIMAP7/RAC2/GIMAP4/GBP5/ARL4C/GIMAP1/GBP4/RAB29/RAB27A/GBP2/RAB8B/IFI44L/TUBA1A/RAP1B/SAMHD1/CDC42	16
GO:0032561	guanyl ribonucleotide binding	16/388	398/18367	0.0108994614193753	0.100052323960216	GIMAP7/RAC2/GIMAP4/GBP5/ARL4C/GIMAP1/GBP4/RAB29/RAB27A/GBP2/RAB8B/IFI44L/TUBA1A/RAP1B/SAMHD1/CDC42	16
GO:0019207	kinase regulator activity	11/388	233/18367	0.0109376196443964	0.100052323960216	CCL5/RAC2/CCND2/GMFG/CALM1/STK4/CDKN2D/PIK3R1/CCNL1/TAOK3/DAZAP2	11
GO:0045296	cadherin binding	14/388	332/18367	0.0113716568045556	0.102344911241001	FXYD5/EFHD2/CNN2/FLNA/STAT1/PFN1/YWHAZ/TLN1/EEF1D/TES/MACF1/ARGLU1/DDX6/CLIC1	14
GO:0019887	protein kinase regulator activity	10/388	204/18367	0.0116841453948764	0.103488144926048	CCL5/RAC2/CCND2/GMFG/CALM1/STK4/CDKN2D/CCNL1/TAOK3/DAZAP2	10
GO:0070412	R-SMAD binding	3/388	23/18367	0.0121066354892297	0.105554728171722	DDX5/JUN/FOS	3
GO:0003924	GTPase activity	14/388	337/18367	0.0128209858039534	0.110063231978554	GIMAP7/RAC2/ARHGDIB/GBP5/ARL4C/GBP4/RGS1/RAB29/RAB27A/GBP2/RAB8B/TUBA1A/RAP1B/CDC42	14
GO:0043274	phospholipase binding	3/388	24/18367	0.013623209341733	0.113458967353537	FYN/LCK/WAS	3
GO:0043495	protein-membrane adaptor activity	3/388	24/18367	0.013623209341733	0.113458967353537	SYNE1/SUN2/SLC9A3R1	3
GO:0019903	protein phosphatase binding	8/388	150/18367	0.0145003026643228	0.118987777745473	SKAP1/LCK/JAK1/STAT1/PIK3R1/CSK/PPP1R15A/STAT3	8
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	17/388	450/18367	0.0155490009121989	0.125744094333434	ETS1/IKZF3/MYBL1/IRF1/KLF6/JUNB/NR4A2/JUN/FOS/LITAF/JUND/REL/ELF1/KLF13/IRF2/STAT3/FOSB	17
GO:0004714	transmembrane receptor protein tyrosine kinase activity	7/388	124/18367	0.0162788877889764	0.128090300707577	FYN/LCK/MATK/TXK/JAK1/CSK/CLK1	7
GO:0004896	cytokine receptor activity	6/388	97/18367	0.0169056498039027	0.128090300707577	IL7R/IL2RG/IL2RB/CXCR4/CD44/IL10RA	6
GO:0035254	glutamate receptor binding	4/388	47/18367	0.0171204484574793	0.128090300707577	FYN/CALM1/MYL12A/SLC9A3R1	4
GO:0001216	DNA-binding transcription activator activity	17/388	456/18367	0.0174637841158134	0.128090300707577	ETS1/IKZF3/MYBL1/IRF1/KLF6/JUNB/NR4A2/JUN/FOS/LITAF/JUND/REL/ELF1/KLF13/IRF2/STAT3/FOSB	17
GO:0004690	cyclic nucleotide-dependent protein kinase activity	2/388	10/18367	0.0179050957978333	0.128090300707577	PRKACB/AKAP13	2
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	2/388	10/18367	0.0179050957978333	0.128090300707577	PTPN22/PTPN4	2
GO:0008330	protein tyrosine/threonine phosphatase activity	2/388	10/18367	0.0179050957978333	0.128090300707577	DUSP2/DUSP1	2
GO:0047844	deoxycytidine deaminase activity	2/388	10/18367	0.0179050957978333	0.128090300707577	APOBEC3G/APOBEC3C	2
GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	2/388	10/18367	0.0179050957978333	0.128090300707577	CASP8/CFLAR	2
GO:0019864	IgG binding	2/388	11/18367	0.0215816671513529	0.150532128380686	FCER1G/FCGR3A	2
GO:0099186	structural constituent of postsynapse	2/388	11/18367	0.0215816671513529	0.150532128380686	ACTB/ACTG1	2
GO:0051059	NF-kappaB binding	3/388	29/18367	0.0227652631867057	0.156217586996683	MTDH/COMMD6/NFKBIA	3
GO:0044325	transmembrane transporter binding	7/388	133/18367	0.0229567063328459	0.156217586996683	FYN/CALM1/FLNA/ID2/YWHAZ/VAMP2/PYCARD	7
GO:0003724	RNA helicase activity	5/388	77/18367	0.0234603442782364	0.157721350689831	DDX5/DDX24/EIF4A2/DDX6/DDX17	5
GO:1990782	protein tyrosine kinase binding	6/388	105/18367	0.0239730059071996	0.159249253526397	CD2/CD247/DOK2/PIK3R1/CBLB/DAZAP2	6
GO:0030971	receptor tyrosine kinase binding	5/388	78/18367	0.0246481647740547	0.161807952281441	CD2/DOK2/PIK3R1/CBLB/DAZAP2	5
GO:0004126	cytidine deaminase activity	2/388	12/18367	0.0255408513932913	0.162006953199079	APOBEC3G/APOBEC3C	2
GO:0061578	Lys63-specific deubiquitinase activity	2/388	12/18367	0.0255408513932913	0.162006953199079	TNFAIP3/CYLD	2
GO:0004713	protein tyrosine kinase activity	7/388	136/18367	0.0255494836586361	0.162006953199079	FYN/LCK/MATK/TXK/JAK1/CSK/CLK1	7
GO:0008186	ATP-dependent activity, acting on RNA	5/388	79/18367	0.0258739723974921	0.162221085368546	DDX5/DDX24/EIF4A2/DDX6/DDX17	5
GO:0019955	cytokine binding	7/388	139/18367	0.0283358127605954	0.175682039115692	IL2RG/IL2RB/CXCR4/ITGA4/PLP2/ZFP36/IL10RA	7
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/388	13/18367	0.029769131919879	0.180556256644484	DUSP2/DUSP1	2
GO:0031386	protein tag	2/388	13/18367	0.029769131919879	0.180556256644484	ISG15/RPS27A	2
GO:0004721	phosphoprotein phosphatase activity	8/388	174/18367	0.0318167582540759	0.190900549524455	PTPRC/DUSP2/LCK/PTPN22/PTPN4/DUSP1/PTPN6/PTP4A2	8
GO:0019199	transmembrane receptor protein kinase activity	7/388	143/18367	0.0323614242865735	0.192102922892639	FYN/LCK/MATK/TXK/JAK1/CSK/CLK1	7
GO:0005178	integrin binding	7/388	144/18367	0.0334245237484467	0.195034861844583	LCP1/ITGB2/ITGA4/ICAM3/TLN1/ISG15/CD81	7
GO:0004298	threonine-type endopeptidase activity	2/388	14/18367	0.0342534345175074	0.195034861844583	PSMB9/PSMB8	2
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/388	14/18367	0.0342534345175074	0.195034861844583	DOK2/PIK3R1	2
GO:0035259	glucocorticoid receptor binding	2/388	14/18367	0.0342534345175074	0.195034861844583	NR4A2/STAT3	2
GO:0004674	protein serine/threonine kinase activity	14/388	386/18367	0.0356778004429912	0.201093057042314	STK4/STK17B/CCL3/PRKACB/ATM/STK17A/STK10/PRKCH/AKAP13/RPS6KA3/PIM1/TAOK3/CLK1/ROCK1	14
GO:0050998	nitric-oxide synthase binding	2/388	15/18367	0.0389811147827429	0.215361010383867	CALM1/ACTB	2
GO:1904680	peptide transmembrane transporter activity	2/388	15/18367	0.0389811147827429	0.215361010383867	TAP1/TAPBP	2
GO:0004698	calcium-dependent protein kinase C activity	2/388	16/18367	0.0439399458742483	0.238043590270199	CCL3/PRKCH	2
GO:0005521	lamin binding	2/388	16/18367	0.0439399458742483	0.238043590270199	SYNE1/SUN2	2
GO:0033218	amide binding	14/388	400/18367	0.0457196340012791	0.245303420891478	HLA-A/HLA-B/HLA-C/HLA-E/CRIP1/HLA-F/ITM2A/ITGB2/TAP1/PIK3R1/SORL1/TAPBP/LNPEP/NFKBIA	14
GO:0005085	guanyl-nucleotide exchange factor activity	9/388	223/18367	0.0478795721101208	0.246918049335575	RASGRP1/DENND2D/TAGAP/ARHGEF1/CYTH1/EEF1D/ARHGEF3/EEF1B2/AKAP13	9
GO:0008022	protein C-terminus binding	8/388	189/18367	0.0478941987873989	0.246918049335575	CORO1A/LCK/TNFAIP3/EPB41/PABPC1/CSK/VAMP2/NCL	8
GO:0004386	helicase activity	7/388	156/18367	0.0480208379293487	0.246918049335575	DDX5/DDX24/EIF4A2/ATRX/CHD9/DDX6/DDX17	7
GO:0004697	protein kinase C activity	2/388	17/18367	0.0491181065882595	0.246918049335575	CCL3/PRKCH	2
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/388	17/18367	0.0491181065882595	0.246918049335575	PTPRC/PTPN6	2
GO:0019198	transmembrane receptor protein phosphatase activity	2/388	17/18367	0.0491181065882595	0.246918049335575	PTPRC/PTPN6	2
GO:0043024	ribosomal small subunit binding	2/388	17/18367	0.0491181065882595	0.246918049335575	EIF1/PIM1	2
GO:0060090	molecular adaptor activity	13/388	369/18367	0.0506914656079069	0.25237363651417	CD3E/CD3G/SYNE1/LAT/DOK2/TRIM22/SUN2/CDC42SE2/PIK3R1/VAMP2/SLC9A3R1/AKAP13/STAT3	13
GO:0003925	G protein activity	3/388	40/18367	0.0520124878120602	0.25237363651417	RAB27A/RAP1B/CDC42	3
GO:0042169	SH2 domain binding	3/388	40/18367	0.0520124878120602	0.25237363651417	SKAP1/LCK/PTPN6	3
GO:0043014	alpha-tubulin binding	3/388	40/18367	0.0520124878120602	0.25237363651417	FYN/ARL4C/OFD1	3
GO:0140030	modification-dependent protein binding	7/388	160/18367	0.0536638288756841	0.255574174119349	TNFAIP3/LAPTM5/KMT2A/KMT2E/PTPN6/MPHOSPH8/ATRX	7
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/388	18/18367	0.0545041697494668	0.255574174119349	CDC42/DAZAP2	2
GO:0033549	MAP kinase phosphatase activity	2/388	18/18367	0.0545041697494668	0.255574174119349	DUSP2/DUSP1	2
GO:0098918	structural constituent of synapse	2/388	18/18367	0.0545041697494668	0.255574174119349	ACTB/ACTG1	2
GO:0001046	core promoter sequence-specific DNA binding	3/388	42/18367	0.0586267567736466	0.272614418997457	STAT1/FOS/DRAP1	3
GO:0003746	translation elongation factor activity	2/388	19/18367	0.0600870909093499	0.277095840722457	EEF1D/EEF1B2	2
GO:0030246	carbohydrate binding	10/388	271/18367	0.0627792582595639	0.287137918924891	KLRB1/KLRD1/CD69/KLRC1/KLRF1/CLEC2B/KLRG1/CLEC2D/LGALS1/SLC2A3	10
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/388	20/18367	0.0658561973442099	0.298762261122513	STAT1/FOS	2
GO:0002020	protease binding	6/388	135/18367	0.0669260580286676	0.301167261129004	MBP/TNF/TNFAIP3/CARD16/PYCARD/CFLAR	6
GO:0048156	tau protein binding	3/388	45/18367	0.0692472241385413	0.309119608554448	FYN/ACTB/ROCK1	3
GO:0003725	double-stranded RNA binding	4/388	74/18367	0.0713863590070316	0.313008257489797	MSN/VIM/MBNL1/MTDH	4
GO:0005123	death receptor binding	2/388	21/18367	0.0718011773453297	0.313008257489797	CASP8/CFLAR	2
GO:0140416	transcription regulator inhibitor activity	2/388	21/18367	0.0718011773453297	0.313008257489797	ID2/LYAR	2
GO:0019003	GDP binding	4/388	75/18367	0.0742139187252576	0.321018346113905	RAB29/RAB27A/RAB8B/RAP1B	4
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/388	47/18367	0.0767753722106899	0.326879210112673	DUSP2/DUSP1/PTP4A2	3
GO:0045182	translation regulator activity	6/388	140/18367	0.0767875486707481	0.326879210112673	RPL10/EIF1/PABPC1/EEF1D/EEF1B2/EIF4A2	6
GO:0008320	protein transmembrane transporter activity	2/388	22/18367	0.0779120697938809	0.326879210112673	TOMM7/MCL1	2
GO:0050321	tau-protein kinase activity	2/388	22/18367	0.0779120697938809	0.326879210112673	FYN/ROCK1	2
GO:0090079	translation regulator activity, nucleic acid binding	5/388	108/18367	0.0788934842367544	0.328526598538126	EIF1/PABPC1/EEF1D/EEF1B2/EIF4A2	5
GO:0106310	protein serine kinase activity	12/388	360/18367	0.081257090475937	0.335862640633873	STK4/STK17B/PRKACB/ATM/STK17A/STK10/PRKCH/RPS6KA3/PIM1/TAOK3/CLK1/ROCK1	12
GO:0047485	protein N-terminus binding	5/388	110/18367	0.0838121377970847	0.338253274384766	ALOX5AP/CALM1/ATM/EPB41/SLC9A3R1	5
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/388	23/18367	0.0841792540133715	0.338253274384766	CCL3/PRKCH	2
GO:0019865	immunoglobulin binding	2/388	23/18367	0.0841792540133715	0.338253274384766	FCER1G/FCGR3A	2
GO:0043539	protein serine/threonine kinase activator activity	3/388	49/18367	0.0846461023253093	0.338253274384766	CALM1/STK4/DAZAP2	3
GO:0016922	nuclear receptor binding	6/388	144/18367	0.0852373730962456	0.338253274384766	DDX5/NR4A2/STAT1/JUND/STAT3/PRMT2	6
GO:0034987	immunoglobulin receptor binding	4/388	79/18367	0.0860787902556216	0.338253274384766	TRDC/TRBC1/TRBC2/FLNA	4
GO:0046332	SMAD binding	4/388	79/18367	0.0860787902556216	0.338253274384766	DDX5/FLNA/JUN/FOS	4
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/388	50/18367	0.0887055119019482	0.346137591897113	CCND2/CDKN2D/CCNL1	3
GO:0010857	calcium-dependent protein kinase activity	2/388	24/18367	0.0905934398926113	0.346240681233405	CCL3/PRKCH	2
GO:0019957	C-C chemokine binding	2/388	24/18367	0.0905934398926113	0.346240681233405	CXCR4/ZFP36	2
GO:0070003	threonine-type peptidase activity	2/388	24/18367	0.0905934398926113	0.346240681233405	PSMB9/PSMB8	2
GO:0004879	nuclear receptor activity	3/388	52/18367	0.0970632568431875	0.361381848773095	RORA/NR4A2/STAT3	3
GO:0098531	ligand-activated transcription factor activity	3/388	52/18367	0.0970632568431875	0.361381848773095	RORA/NR4A2/STAT3	3
GO:0035035	histone acetyltransferase binding	2/388	25/18367	0.0971456582723373	0.361381848773095	ETS1/STAT1	2
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/388	25/18367	0.0971456582723373	0.361381848773095	ZFP36L2/ZFP36	2
GO:0008135	translation factor activity, RNA binding	4/388	84/18367	0.102114875410048	0.377351658800044	EIF1/EEF1D/EEF1B2/EIF4A2	4
GO:0042974	retinoic acid receptor binding	2/388	26/18367	0.103827251588813	0.381155305174721	NR4A2/PRMT2	2
GO:0022884	macromolecule transmembrane transporter activity	2/388	27/18367	0.110629864767877	0.395714516285097	TOMM7/MCL1	2
GO:0023026	MHC class II protein complex binding	2/388	27/18367	0.110629864767877	0.395714516285097	B2M/CD81	2
GO:0030507	spectrin binding	2/388	27/18367	0.110629864767877	0.395714516285097	PTPRC/EPB41	2
GO:0048027	mRNA 5'-UTR binding	2/388	27/18367	0.110629864767877	0.395714516285097	RPL41/NCL	2
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/388	56/18367	0.114681376801614	0.407593683154781	CST7/CARD16/RPS6KA3	3
GO:0048306	calcium-dependent protein binding	4/388	88/18367	0.115856622847212	0.40916452878952	S100A4/CALM1/DDX5/VAMP2	4
GO:0050681	androgen receptor binding	2/388	28/18367	0.11754543636308	0.412517946481752	DDX5/PRMT2	2
GO:0019888	protein phosphatase regulator activity	4/388	89/18367	0.119412782384768	0.416452078566877	CALM1/PPP2R5C/PPP1R15A/PPP1R2	4
GO:0016887	ATP hydrolysis activity	9/388	272/18367	0.123799671701351	0.429069669623315	RNF213/DDX5/DDX24/KIF2A/EIF4A2/ATRX/CHD9/DDX6/DDX17	9
GO:0036002	pre-mRNA binding	3/388	59/18367	0.128623490144507	0.443036466053302	CELF2/DDX5/SF1	3
GO:0005516	calmodulin binding	7/388	201/18367	0.134524550936655	0.459058794608149	MBP/DDX5/CNN2/RGS1/EPB41/MYO1F/VAMP2	7
GO:0140678	molecular function inhibitor activity	5/388	128/18367	0.13492050594218	0.459058794608149	TXNIP/CALM1/ID2/LYAR/PPP1R12A	5
GO:0140318	protein transporter activity	2/388	31/18367	0.138893512109893	0.469712604589819	TOMM7/MCL1	2
GO:0001222	transcription corepressor binding	2/388	32/18367	0.146185878447035	0.485545953413365	RORA/STAT1	2
GO:0050699	WW domain binding	2/388	32/18367	0.146185878447035	0.485545953413365	LITAF/DAZAP2	2
GO:0140658	ATP-dependent chromatin remodeler activity	2/388	32/18367	0.146185878447035	0.485545953413365	ATRX/CHD9	2
GO:0048018	receptor ligand activity	14/388	487/18367	0.152197562224816	0.498161009573154	CCL4/CCL5/IL32/XCL2/XCL1/LTB/TNF/GMFG/CCL3/TGFB1/CCL3L3/SEMA4D/CMTM3/CKLF	14
GO:0001530	lipopolysaccharide binding	2/388	33/18367	0.153555006535094	0.498161009573154	SPON2/ZRANB2	2
GO:0019239	deaminase activity	2/388	33/18367	0.153555006535094	0.498161009573154	APOBEC3G/APOBEC3C	2
GO:0051427	hormone receptor binding	2/388	33/18367	0.153555006535094	0.498161009573154	FYN/JAK1	2
GO:0030295	protein kinase activator activity	4/388	101/18367	0.165492938858055	0.531196751822951	CCL5/CALM1/STK4/DAZAP2	4
GO:0030546	signaling receptor activator activity	14/388	495/18367	0.165908025499031	0.531196751822951	CCL4/CCL5/IL32/XCL2/XCL1/LTB/TNF/GMFG/CCL3/TGFB1/CCL3L3/SEMA4D/CMTM3/CKLF	14
GO:0097110	scaffold protein binding	3/388	67/18367	0.168418204232437	0.531196751822951	FYN/VIM/CASP8	3
GO:0000175	3'-5'-exoribonuclease activity	2/388	35/18367	0.168497894395452	0.531196751822951	ISG20/CNOT6L	2
GO:0042887	amide transmembrane transporter activity	2/388	35/18367	0.168497894395452	0.531196751822951	TAP1/TAPBP	2
GO:0019843	rRNA binding	3/388	68/18367	0.173624217656989	0.535915004290684	RPS4X/GTF3A/RPL19	3
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/388	36/18367	0.176059415079192	0.535915004290684	APOBEC3G/APOBEC3C	2
GO:0042162	telomeric DNA binding	2/388	36/18367	0.176059415079192	0.535915004290684	TERF2IP/NCL	2
GO:0097718	disordered domain specific binding	2/388	36/18367	0.176059415079192	0.535915004290684	FYN/CALM1	2
GO:0019838	growth factor binding	5/388	141/18367	0.178645088408112	0.535915004290684	IL2RG/FGFBP2/IL2RB/IL10RA/DUSP1	5
GO:0042056	chemoattractant activity	2/388	37/18367	0.183673205289546	0.535915004290684	CCL5/CCL3	2
GO:0004860	protein kinase inhibitor activity	3/388	70/18367	0.184169023056246	0.535915004290684	GMFG/CDKN2D/TAOK3	3
GO:0031491	nucleosome binding	3/388	71/18367	0.18950394149278	0.535915004290684	ACTB/MLLT6/HP1BP3	3
GO:0019209	kinase activator activity	4/388	107/18367	0.190590697800979	0.535915004290684	CCL5/CALM1/STK4/DAZAP2	4
GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	2/388	38/18367	0.191333701905263	0.535915004290684	ISG20/CNOT6L	2
GO:0004955	prostaglandin receptor activity	1/388	10/18367	0.192299980388424	0.535915004290684	PTGER4	1
GO:0008097	5S rRNA binding	1/388	10/18367	0.192299980388424	0.535915004290684	GTF3A	1
GO:0008172	S-methyltransferase activity	1/388	10/18367	0.192299980388424	0.535915004290684	KMT2A	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/388	10/18367	0.192299980388424	0.535915004290684	CYBA	1
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/388	10/18367	0.192299980388424	0.535915004290684	ATM	1
GO:0030957	Tat protein binding	1/388	10/18367	0.192299980388424	0.535915004290684	ACTB	1
GO:0034511	U3 snoRNA binding	1/388	10/18367	0.192299980388424	0.535915004290684	ISG20	1
GO:0034713	type I transforming growth factor beta receptor binding	1/388	10/18367	0.192299980388424	0.535915004290684	TGFB1	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/388	10/18367	0.192299980388424	0.535915004290684	PIK3R1	1
GO:0050786	RAGE receptor binding	1/388	10/18367	0.192299980388424	0.535915004290684	S100A4	1
GO:0098505	G-rich strand telomeric DNA binding	1/388	10/18367	0.192299980388424	0.535915004290684	TERF2IP	1
GO:0035064	methylated histone binding	3/388	73/18367	0.200289238779266	0.535915004290684	KMT2E/MPHOSPH8/ATRX	3
GO:0140034	methylation-dependent protein binding	3/388	73/18367	0.200289238779266	0.535915004290684	KMT2E/MPHOSPH8/ATRX	3
GO:0003714	transcription corepressor activity	6/388	187/18367	0.204561127603962	0.535915004290684	TRIM22/N4BP2L2/BTG2/DRAP1/SF1/ATF7IP	6
GO:0019210	kinase inhibitor activity	3/388	74/18367	0.205735839333022	0.535915004290684	GMFG/CDKN2D/TAOK3	3
GO:0004532	exoribonuclease activity	2/388	40/18367	0.206773608421498	0.535915004290684	ISG20/CNOT6L	2
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/388	40/18367	0.206773608421498	0.535915004290684	RPS6KA3/PYCARD	2
GO:0000774	adenyl-nucleotide exchange factor activity	1/388	11/18367	0.209371811712131	0.535915004290684	PFN1	1
GO:0004143	diacylglycerol kinase activity	1/388	11/18367	0.209371811712131	0.535915004290684	DGKZ	1
GO:0004954	prostanoid receptor activity	1/388	11/18367	0.209371811712131	0.535915004290684	PTGER4	1
GO:0005078	MAP-kinase scaffold activity	1/388	11/18367	0.209371811712131	0.535915004290684	AKAP13	1
GO:0005536	glucose binding	1/388	11/18367	0.209371811712131	0.535915004290684	SLC2A3	1
GO:0016273	arginine N-methyltransferase activity	1/388	11/18367	0.209371811712131	0.535915004290684	PRMT2	1
GO:0016274	protein-arginine N-methyltransferase activity	1/388	11/18367	0.209371811712131	0.535915004290684	PRMT2	1
GO:0019855	calcium channel inhibitor activity	1/388	11/18367	0.209371811712131	0.535915004290684	CALM1	1
GO:0031996	thioesterase binding	1/388	11/18367	0.209371811712131	0.535915004290684	CDC42	1
GO:0043560	insulin receptor substrate binding	1/388	11/18367	0.209371811712131	0.535915004290684	PIK3R1	1
GO:0051400	BH domain binding	1/388	11/18367	0.209371811712131	0.535915004290684	MCL1	1
GO:0070513	death domain binding	1/388	11/18367	0.209371811712131	0.535915004290684	MCL1	1
GO:0140036	ubiquitin-dependent protein binding	1/388	11/18367	0.209371811712131	0.535915004290684	LAPTM5	1
GO:1990459	transferrin receptor binding	1/388	11/18367	0.209371811712131	0.535915004290684	CD81	1
GO:0008234	cysteine-type peptidase activity	6/388	190/18367	0.214522287916825	0.541436541610212	CTSW/TNFAIP3/CASP8/CYLD/PYCARD/CFLAR	6
GO:0061134	peptidase regulator activity	7/388	230/18367	0.214672156979309	0.541436541610212	CST7/BST2/PSME1/CARD16/RPS6KA3/PYCARD/ROCK1	7
GO:0001618	virus receptor activity	3/388	76/18367	0.21672763679153	0.541436541610212	CXCR4/SELPLG/CD81	3
GO:0140272	exogenous protein binding	3/388	77/18367	0.222269170095646	0.541436541610212	CXCR4/SELPLG/CD81	3
GO:0019894	kinesin binding	2/388	42/18367	0.222338727824964	0.541436541610212	RAB29/ACTB	2
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/388	12/18367	0.226083717195662	0.541436541610212	CDKN2D	1
GO:0005095	GTPase inhibitor activity	1/388	12/18367	0.226083717195662	0.541436541610212	CDC42SE1	1
GO:0005165	neurotrophin receptor binding	1/388	12/18367	0.226083717195662	0.541436541610212	PIK3R1	1
GO:0008296	3'-5'-exodeoxyribonuclease activity	1/388	12/18367	0.226083717195662	0.541436541610212	ISG20	1
GO:0017166	vinculin binding	1/388	12/18367	0.226083717195662	0.541436541610212	TLN1	1
GO:0035004	phosphatidylinositol 3-kinase activity	1/388	12/18367	0.226083717195662	0.541436541610212	ATM	1
GO:0042975	peroxisome proliferator activated receptor binding	1/388	12/18367	0.226083717195662	0.541436541610212	PRMT2	1
GO:0043047	single-stranded telomeric DNA binding	1/388	12/18367	0.226083717195662	0.541436541610212	TERF2IP	1
GO:0043422	protein kinase B binding	1/388	12/18367	0.226083717195662	0.541436541610212	SRSF5	1
GO:0089720	caspase binding	1/388	12/18367	0.226083717195662	0.541436541610212	CARD16	1
GO:0016791	phosphatase activity	8/388	275/18367	0.227281926077381	0.541512857406559	PTPRC/DUSP2/LCK/PTPN22/PTPN4/DUSP1/PTPN6/PTP4A2	8
GO:0061135	endopeptidase regulator activity	6/388	194/18367	0.228056490126418	0.541512857406559	CST7/BST2/PSME1/CARD16/RPS6KA3/ROCK1	6
GO:0016504	peptidase activator activity	2/388	43/18367	0.230156460626853	0.543306596026117	PSME1/PYCARD	2
GO:0004535	poly(A)-specific ribonuclease activity	1/388	13/18367	0.242443265968644	0.543306596026117	CNOT6L	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/388	13/18367	0.242443265968644	0.543306596026117	PPP1R2	1
GO:0008179	adenylate cyclase binding	1/388	13/18367	0.242443265968644	0.543306596026117	CALM1	1
GO:0008494	translation activator activity	1/388	13/18367	0.242443265968644	0.543306596026117	PABPC1	1
GO:0031432	titin binding	1/388	13/18367	0.242443265968644	0.543306596026117	CALM1	1
GO:0032036	myosin heavy chain binding	1/388	13/18367	0.242443265968644	0.543306596026117	CORO1A	1
GO:0034236	protein kinase A catalytic subunit binding	1/388	13/18367	0.242443265968644	0.543306596026117	CSK	1
GO:0045159	myosin II binding	1/388	13/18367	0.242443265968644	0.543306596026117	SLC9A3R1	1
GO:0051011	microtubule minus-end binding	1/388	13/18367	0.242443265968644	0.543306596026117	MACF1	1
GO:0060590	ATPase regulator activity	1/388	13/18367	0.242443265968644	0.543306596026117	PFN1	1
GO:0061133	endopeptidase activator activity	1/388	13/18367	0.242443265968644	0.543306596026117	PSME1	1
GO:0070700	BMP receptor binding	1/388	13/18367	0.242443265968644	0.543306596026117	PYCARD	1
GO:0140035	ubiquitination-like modification-dependent protein binding	1/388	13/18367	0.242443265968644	0.543306596026117	LAPTM5	1
GO:0004197	cysteine-type endopeptidase activity	4/388	119/18367	0.243904490472926	0.54439482273557	CTSW/CASP8/PYCARD/CFLAR	4
GO:0042578	phosphoric ester hydrolase activity	10/388	366/18367	0.247493528201158	0.55020473600098	CCL5/PTPRC/DUSP2/LCK/PTPN22/PTPN4/DUSP1/SAMHD1/PTPN6/PTP4A2	10
GO:0003730	mRNA 3'-UTR binding	6/388	201/18367	0.252366600443244	0.558811758124326	ZFP36L2/CELF2/DDX5/ZFP36/RPL41/PABPC1	6
GO:0008474	palmitoyl-(protein) hydrolase activity	1/388	14/18367	0.258457868387962	0.559036372104726	ABHD17A	1
GO:0019992	diacylglycerol binding	1/388	14/18367	0.258457868387962	0.559036372104726	RASGRP1	1
GO:0036041	long-chain fatty acid binding	1/388	14/18367	0.258457868387962	0.559036372104726	ALOX5AP	1
GO:0071837	HMG box domain binding	1/388	14/18367	0.258457868387962	0.559036372104726	JUN	1
GO:0098599	palmitoyl hydrolase activity	1/388	14/18367	0.258457868387962	0.559036372104726	ABHD17A	1
GO:0042393	histone binding	7/388	244/18367	0.25847918280111	0.559036372104726	STAT1/KMT2A/KMT2E/MLLT6/ANP32E/MPHOSPH8/ATRX	7
GO:0001540	amyloid-beta binding	3/388	84/18367	0.261746407765212	0.562379437068926	ITM2A/ITGB2/SORL1	3
GO:0008013	beta-catenin binding	3/388	85/18367	0.267463604400149	0.562379437068926	RORA/NR4A2/SLC9A3R1	3
GO:0015026	coreceptor activity	2/388	48/18367	0.269426288291738	0.562379437068926	CXCR4/ITGA4	2
GO:0001846	opsonin binding	1/388	15/18367	0.274134779359763	0.562379437068926	ITGB2	1
GO:0004953	icosanoid receptor activity	1/388	15/18367	0.274134779359763	0.562379437068926	PTGER4	1
GO:0005041	low-density lipoprotein particle receptor activity	1/388	15/18367	0.274134779359763	0.562379437068926	SORL1	1
GO:0005545	1-phosphatidylinositol binding	1/388	15/18367	0.274134779359763	0.562379437068926	EPB41	1
GO:0010851	cyclase regulator activity	1/388	15/18367	0.274134779359763	0.562379437068926	CALM1	1
GO:0016846	carbon-sulfur lyase activity	1/388	15/18367	0.274134779359763	0.562379437068926	ALOX5AP	1
GO:0019215	intermediate filament binding	1/388	15/18367	0.274134779359763	0.562379437068926	VIM	1
GO:0032794	GTPase activating protein binding	1/388	15/18367	0.274134779359763	0.562379437068926	FMNL1	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/388	15/18367	0.274134779359763	0.562379437068926	CYBA	1
GO:0071933	Arp2/3 complex binding	1/388	15/18367	0.274134779359763	0.562379437068926	GMFG	1
GO:0098847	sequence-specific single stranded DNA binding	1/388	15/18367	0.274134779359763	0.562379437068926	TERF2IP	1
GO:0016763	pentosyltransferase activity	2/388	49/18367	0.277289274928607	0.564698596387455	PARP8/APRT	2
GO:0019212	phosphatase inhibitor activity	2/388	49/18367	0.277289274928607	0.564698596387455	ANP32E/PPP1R2	2
GO:0140359	ABC-type transporter activity	2/388	50/18367	0.285146931721384	0.564791799609822	TAP1/TAPBP	2
GO:0005092	GDP-dissociation inhibitor activity	1/388	16/18367	0.289481101592131	0.564791799609822	ARHGDIB	1
GO:0005159	insulin-like growth factor receptor binding	1/388	16/18367	0.289481101592131	0.564791799609822	PIK3R1	1
GO:0005523	tropomyosin binding	1/388	16/18367	0.289481101592131	0.564791799609822	PYCARD	1
GO:0008191	metalloendopeptidase inhibitor activity	1/388	16/18367	0.289481101592131	0.564791799609822	BST2	1
GO:0016208	AMP binding	1/388	16/18367	0.289481101592131	0.564791799609822	APRT	1
GO:0016307	phosphatidylinositol phosphate kinase activity	1/388	16/18367	0.289481101592131	0.564791799609822	PIP4K2A	1
GO:0035497	cAMP response element binding	1/388	16/18367	0.289481101592131	0.564791799609822	JUN	1
GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	1/388	16/18367	0.289481101592131	0.564791799609822	PIK3R1	1
GO:0050700	CARD domain binding	1/388	16/18367	0.289481101592131	0.564791799609822	CARD16	1
GO:0070492	oligosaccharide binding	1/388	16/18367	0.289481101592131	0.564791799609822	LGALS1	1
GO:1990404	protein ADP-ribosylase activity	1/388	16/18367	0.289481101592131	0.564791799609822	PARP8	1
GO:0003743	translation initiation factor activity	2/388	51/18367	0.292995982617078	0.567679716320589	EIF1/EIF4A2	2
GO:0051018	protein kinase A binding	2/388	51/18367	0.292995982617078	0.567679716320589	CSK/AKAP13	2
GO:0004175	endopeptidase activity	11/388	430/18367	0.301445156745416	0.568271284746385	GZMA/GZMK/GZMB/CTSW/GZMH/GZMM/PSMB9/PSMB8/CASP8/PYCARD/CFLAR	11
GO:0003951	NAD+ kinase activity	1/388	17/18367	0.304503788779873	0.568271284746385	DGKZ	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/388	17/18367	0.304503788779873	0.568271284746385	PYCARD	1
GO:0017081	chloride channel regulator activity	1/388	17/18367	0.304503788779873	0.568271284746385	SLC9A3R1	1
GO:0030169	low-density lipoprotein particle binding	1/388	17/18367	0.304503788779873	0.568271284746385	SORL1	1
GO:0031489	myosin V binding	1/388	17/18367	0.304503788779873	0.568271284746385	RAB27A	1
GO:0032393	MHC class I receptor activity	1/388	17/18367	0.304503788779873	0.568271284746385	KLRF1	1
GO:0042800	histone methyltransferase activity (H3-K4 specific)	1/388	17/18367	0.304503788779873	0.568271284746385	KMT2A	1
GO:0043395	heparan sulfate proteoglycan binding	1/388	17/18367	0.304503788779873	0.568271284746385	PTPRC	1
GO:0046965	retinoid X receptor binding	1/388	17/18367	0.304503788779873	0.568271284746385	NR4A2	1
GO:0050780	dopamine receptor binding	1/388	17/18367	0.304503788779873	0.568271284746385	SLC9A3R1	1
GO:0004252	serine-type endopeptidase activity	5/388	174/18367	0.307097724214113	0.570610431736175	GZMA/GZMK/GZMB/GZMH/GZMM	5
GO:0043130	ubiquitin binding	3/388	92/18367	0.307802401348725	0.570610431736175	CXCR4/TNFAIP3/UBE2L6	3
GO:0008408	3'-5' exonuclease activity	2/388	54/18367	0.316460814213391	0.584718987851233	ISG20/CNOT6L	2
GO:0030228	lipoprotein particle receptor activity	1/388	18/18367	0.319209648722838	0.587851432301464	SORL1	1
GO:0005080	protein kinase C binding	2/388	55/18367	0.324245416981907	0.595160995644422	PLEK/FLNA	2
GO:0004866	endopeptidase inhibitor activity	5/388	180/18367	0.332003450232268	0.605424617122975	CST7/BST2/CARD16/RPS6KA3/ROCK1	5
GO:0042054	histone methyltransferase activity	2/388	56/18367	0.332007048099696	0.605424617122975	KMT2A/PRMT2	2
GO:0052742	phosphatidylinositol kinase activity	1/388	19/18367	0.333605346379143	0.606357600259159	ATM	1
GO:0099106	ion channel regulator activity	4/388	139/18367	0.338276135928952	0.61011054410347	CALM1/FXYD5/FLNA/SLC9A3R1	4
GO:0004722	protein serine/threonine phosphatase activity	3/388	98/18367	0.342555568424313	0.61011054410347	DUSP2/LCK/DUSP1	3
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/388	20/18367	0.347697406854666	0.61011054410347	DRAP1	1
GO:0016505	peptidase activator activity involved in apoptotic process	1/388	20/18367	0.347697406854666	0.61011054410347	PYCARD	1
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/388	20/18367	0.347697406854666	0.61011054410347	GNPTAB	1
GO:0030296	protein tyrosine kinase activator activity	1/388	20/18367	0.347697406854666	0.61011054410347	CCL5	1
GO:0030506	ankyrin binding	1/388	20/18367	0.347697406854666	0.61011054410347	PTPRC	1
GO:0031681	G-protein beta-subunit binding	1/388	20/18367	0.347697406854666	0.61011054410347	GNG2	1
GO:0031690	adrenergic receptor binding	1/388	20/18367	0.347697406854666	0.61011054410347	SLC9A3R1	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/388	20/18367	0.347697406854666	0.61011054410347	PIK3R1	1
GO:0050145	nucleoside monophosphate kinase activity	1/388	20/18367	0.347697406854666	0.61011054410347	GUK1	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/388	59/18367	0.355129688632321	0.621198640303558	ISG20/CNOT6L	2
GO:0030414	peptidase inhibitor activity	5/388	187/18367	0.361278337839498	0.622569931568562	CST7/BST2/CARD16/RPS6KA3/ROCK1	5
GO:0001848	complement binding	1/388	21/18367	0.361492218330133	0.622569931568562	ITGB2	1
GO:0051428	peptide hormone receptor binding	1/388	21/18367	0.361492218330133	0.622569931568562	FYN	1
GO:0070577	lysine-acetylated histone binding	1/388	21/18367	0.361492218330133	0.622569931568562	KMT2A	1
GO:0140033	acetylation-dependent protein binding	1/388	21/18367	0.361492218330133	0.622569931568562	KMT2A	1
GO:0032934	sterol binding	2/388	60/18367	0.362775571889119	0.622857751120396	RORA/CD81	2
GO:0016247	channel regulator activity	4/388	145/18367	0.367082486884585	0.62608080511231	CALM1/FXYD5/FLNA/SLC9A3R1	4
GO:0004602	glutathione peroxidase activity	1/388	22/18367	0.374996034927097	0.62608080511231	ALOX5AP	1
GO:0005355	glucose transmembrane transporter activity	1/388	22/18367	0.374996034927097	0.62608080511231	SLC2A3	1
GO:0005540	hyaluronic acid binding	1/388	22/18367	0.374996034927097	0.62608080511231	CD44	1
GO:0015149	hexose transmembrane transporter activity	1/388	22/18367	0.374996034927097	0.62608080511231	SLC2A3	1
GO:0017075	syntaxin-1 binding	1/388	22/18367	0.374996034927097	0.62608080511231	VAMP2	1
GO:0030742	GTP-dependent protein binding	1/388	22/18367	0.374996034927097	0.62608080511231	CDC42	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/388	22/18367	0.374996034927097	0.62608080511231	RPS6KA3	1
GO:0008236	serine-type peptidase activity	5/388	191/18367	0.378048483761473	0.62608080511231	GZMA/GZMK/GZMB/GZMH/GZMM	5
GO:0003950	NAD+ ADP-ribosyltransferase activity	1/388	23/18367	0.388214979514085	0.62608080511231	PARP8	1
GO:0004529	exodeoxyribonuclease activity	1/388	23/18367	0.388214979514085	0.62608080511231	ISG20	1
GO:0005158	insulin receptor binding	1/388	23/18367	0.388214979514085	0.62608080511231	PIK3R1	1
GO:0005212	structural constituent of eye lens	1/388	23/18367	0.388214979514085	0.62608080511231	VIM	1
GO:0008143	poly(A) binding	1/388	23/18367	0.388214979514085	0.62608080511231	PABPC1	1
GO:0016493	C-C chemokine receptor activity	1/388	23/18367	0.388214979514085	0.62608080511231	CXCR4	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/388	23/18367	0.388214979514085	0.62608080511231	ALOX5AP	1
GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/388	23/18367	0.388214979514085	0.62608080511231	ISG20	1
GO:0017025	TBP-class protein binding	1/388	23/18367	0.388214979514085	0.62608080511231	DRAP1	1
GO:0030215	semaphorin receptor binding	1/388	23/18367	0.388214979514085	0.62608080511231	SEMA4D	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/388	23/18367	0.388214979514085	0.62608080511231	TNFAIP3	1
GO:0140103	catalytic activity, acting on a glycoprotein	1/388	23/18367	0.388214979514085	0.62608080511231	MGAT4A	1
GO:0017171	serine hydrolase activity	5/388	195/18367	0.394809870580777	0.634881578628453	GZMA/GZMK/GZMB/GZMH/GZMM	5
GO:0001965	G-protein alpha-subunit binding	1/388	24/18367	0.401155046454149	0.635921920231292	RGS1	1
GO:0015145	monosaccharide transmembrane transporter activity	1/388	24/18367	0.401155046454149	0.635921920231292	SLC2A3	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/388	24/18367	0.401155046454149	0.635921920231292	ALOX5AP	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/388	24/18367	0.401155046454149	0.635921920231292	PYCARD	1
GO:0070840	dynein complex binding	1/388	24/18367	0.401155046454149	0.635921920231292	RAB29	1
GO:0005160	transforming growth factor beta receptor binding	1/388	25/18367	0.413822104295058	0.650458406187724	TGFB1	1
GO:0008266	poly(U) RNA binding	1/388	25/18367	0.413822104295058	0.650458406187724	PABPC1	1
GO:0051019	mitogen-activated protein kinase binding	1/388	25/18367	0.413822104295058	0.650458406187724	DUSP1	1
GO:0032182	ubiquitin-like protein binding	3/388	111/18367	0.417048206148367	0.653687918625812	CXCR4/TNFAIP3/UBE2L6	3
GO:0001637	G protein-coupled chemoattractant receptor activity	1/388	26/18367	0.426221898403307	0.658813903903173	CXCR4	1
GO:0004364	glutathione transferase activity	1/388	26/18367	0.426221898403307	0.658813903903173	ALOX5AP	1
GO:0004435	phosphatidylinositol phospholipase C activity	1/388	26/18367	0.426221898403307	0.658813903903173	CCL5	1
GO:0004950	chemokine receptor activity	1/388	26/18367	0.426221898403307	0.658813903903173	CXCR4	1
GO:0042923	neuropeptide binding	1/388	26/18367	0.426221898403307	0.658813903903173	SORL1	1
GO:0004857	enzyme inhibitor activity	2/388	70/18367	0.437052449567267	0.666498392035606	TXNIP/PPP1R12A	2
GO:0001671	ATPase activator activity	1/388	27/18367	0.438360053543131	0.666498392035606	DNAJC1	1
GO:0008139	nuclear localization sequence binding	1/388	27/18367	0.438360053543131	0.666498392035606	NFKBIA	1
GO:0045499	chemorepellent activity	1/388	27/18367	0.438360053543131	0.666498392035606	SEMA4D	1
GO:0051119	sugar transmembrane transporter activity	1/388	27/18367	0.438360053543131	0.666498392035606	SLC2A3	1
GO:0070006	metalloaminopeptidase activity	1/388	27/18367	0.438360053543131	0.666498392035606	LNPEP	1
GO:0004540	ribonuclease activity	3/388	116/18367	0.445022574058884	0.673407601526459	ISG20/SAMHD1/CNOT6L	3
GO:0001968	fibronectin binding	1/388	28/18367	0.450242076401652	0.673407601526459	ITGA4	1
GO:0004629	phospholipase C activity	1/388	28/18367	0.450242076401652	0.673407601526459	CCL5	1
GO:0008187	poly-pyrimidine tract binding	1/388	28/18367	0.450242076401652	0.673407601526459	PABPC1	1
GO:0043236	laminin binding	1/388	28/18367	0.450242076401652	0.673407601526459	LGALS1	1
GO:0046875	ephrin receptor binding	1/388	28/18367	0.450242076401652	0.673407601526459	FYN	1
GO:0003678	DNA helicase activity	2/388	72/18367	0.451352048334938	0.673407601526459	ATRX/CHD9	2
GO:0106306	protein serine phosphatase activity	2/388	73/18367	0.458424240153408	0.678224562626846	DUSP2/DUSP1	2
GO:0106307	protein threonine phosphatase activity	2/388	73/18367	0.458424240153408	0.678224562626846	DUSP2/DUSP1	2
GO:0003712	transcription coregulator activity	11/388	489/18367	0.459135972065076	0.678224562626846	ETS1/BTG1/TRIM22/MTDH/N4BP2L2/BTG2/DRAP1/PRMT2/SF1/ATF7IP/DDX17	11
GO:0033612	receptor serine/threonine kinase binding	1/388	29/18367	0.461873358061293	0.678224562626846	PYCARD	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/388	29/18367	0.461873358061293	0.678224562626846	PLEK	1
GO:0070717	poly-purine tract binding	1/388	29/18367	0.461873358061293	0.678224562626846	PABPC1	1
GO:0022829	wide pore channel activity	1/388	30/18367	0.473259176420559	0.691305289116942	PRF1	1
GO:0046966	thyroid hormone receptor binding	1/388	30/18367	0.473259176420559	0.691305289116942	PRMT2	1
GO:0003713	transcription coactivator activity	6/388	262/18367	0.478631962081306	0.69307133794577	ETS1/TRIM22/MTDH/DRAP1/PRMT2/DDX17	6
GO:0000146	microfilament motor activity	1/388	31/18367	0.484404698564248	0.69307133794577	MYO1F	1
GO:0008157	protein phosphatase 1 binding	1/388	31/18367	0.484404698564248	0.69307133794577	PPP1R15A	1
GO:0031210	phosphatidylcholine binding	1/388	31/18367	0.484404698564248	0.69307133794577	RASGRP1	1
GO:0043015	gamma-tubulin binding	1/388	31/18367	0.484404698564248	0.69307133794577	OFD1	1
GO:0071813	lipoprotein particle binding	1/388	31/18367	0.484404698564248	0.69307133794577	SORL1	1
GO:0071814	protein-lipid complex binding	1/388	31/18367	0.484404698564248	0.69307133794577	SORL1	1
GO:0090482	vitamin transmembrane transporter activity	1/388	31/18367	0.484404698564248	0.69307133794577	SLC2A3	1
GO:0038024	cargo receptor activity	2/388	77/18367	0.486173447932796	0.693822976845269	ITGB2/SORL1	2
GO:0001221	transcription coregulator binding	2/388	78/18367	0.492971730270565	0.69443658432402	RORA/STAT1	2
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3/388	125/18367	0.493948066363003	0.69443658432402	APOBEC3G/APOBEC3C/GLS	3
GO:0001223	transcription coactivator binding	1/388	32/18367	0.495314983084158	0.69443658432402	RORA	1
GO:0030515	snoRNA binding	1/388	32/18367	0.495314983084158	0.69443658432402	ISG20	1
GO:0031624	ubiquitin conjugating enzyme binding	1/388	32/18367	0.495314983084158	0.69443658432402	RNF19A	1
GO:0048019	receptor antagonist activity	1/388	32/18367	0.495314983084158	0.69443658432402	CCL5	1
GO:0051721	protein phosphatase 2A binding	1/388	32/18367	0.495314983084158	0.69443658432402	STAT1	1
GO:0008200	ion channel inhibitor activity	1/388	33/18367	0.505994982351316	0.706423117512121	CALM1	1
GO:0004527	exonuclease activity	2/388	80/18367	0.506396500008689	0.706423117512121	ISG20/CNOT6L	2
GO:0031072	heat shock protein binding	3/388	129/18367	0.515000140012802	0.71508398502564	SPN/ITGB2/ZFP36	3
GO:0016248	channel inhibitor activity	1/388	34/18367	0.51644954474074	0.71508398502564	CALM1	1
GO:0030291	protein serine/threonine kinase inhibitor activity	1/388	34/18367	0.51644954474074	0.71508398502564	CDKN2D	1
GO:0000217	DNA secondary structure binding	1/388	36/18367	0.536701245430591	0.735821363514176	KMT2A	1
GO:0005484	SNAP receptor activity	1/388	36/18367	0.536701245430591	0.735821363514176	VAMP2	1
GO:0043394	proteoglycan binding	1/388	36/18367	0.536701245430591	0.735821363514176	PTPRC	1
GO:0061631	ubiquitin conjugating enzyme activity	1/388	36/18367	0.536701245430591	0.735821363514176	UBE2L6	1
GO:0046982	protein heterodimerization activity	7/388	328/18367	0.542388630263343	0.741796214918983	CD3E/CYBA/NR4A2/PIK3R1/XBP1/DRAP1/MCL1	7
GO:0043531	ADP binding	1/388	37/18367	0.546507579878953	0.745602028294513	TAP1	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/388	38/18367	0.556106873878242	0.75310488324985	FKBP11	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/388	38/18367	0.556106873878242	0.75310488324985	DRAP1	1
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/388	38/18367	0.556106873878242	0.75310488324985	RNF19A	1
GO:0008276	protein methyltransferase activity	2/388	88/18367	0.557729147417139	0.75310488324985	KMT2A/PRMT2	2
GO:0004402	histone acetyltransferase activity	1/388	39/18367	0.56550348760159	0.75310488324985	EPC1	1
GO:0005504	fatty acid binding	1/388	39/18367	0.56550348760159	0.75310488324985	ALOX5AP	1
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/388	39/18367	0.56550348760159	0.75310488324985	ARAP2	1
GO:0016776	phosphotransferase activity, phosphate group as acceptor	1/388	39/18367	0.56550348760159	0.75310488324985	GUK1	1
GO:0050997	quaternary ammonium group binding	1/388	39/18367	0.56550348760159	0.75310488324985	RASGRP1	1
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/388	39/18367	0.56550348760159	0.75310488324985	UBE2L6	1
GO:0140098	catalytic activity, acting on RNA	8/388	386/18367	0.571699853385098	0.755202859794427	ISG20/DDX5/DDX24/SAMHD1/EIF4A2/CNOT6L/DDX6/DDX17	8
GO:0004177	aminopeptidase activity	1/388	40/18367	0.574701689631849	0.755202859794427	LNPEP	1
GO:0015144	carbohydrate transmembrane transporter activity	1/388	40/18367	0.574701689631849	0.755202859794427	SLC2A3	1
GO:0017080	sodium channel regulator activity	1/388	40/18367	0.574701689631849	0.755202859794427	FXYD5	1
GO:0031492	nucleosomal DNA binding	1/388	40/18367	0.574701689631849	0.755202859794427	ACTB	1
GO:0070851	growth factor receptor binding	3/388	141/18367	0.575199310775325	0.755202859794427	FYN/SLC9A3R1/PYCARD	3
GO:0016859	cis-trans isomerase activity	1/388	41/18367	0.583705658880654	0.76099943377431	FKBP11	1
GO:0030331	estrogen receptor binding	1/388	41/18367	0.583705658880654	0.76099943377431	PRMT2	1
GO:0061733	peptide-lysine-N-acetyltransferase activity	1/388	41/18367	0.583705658880654	0.76099943377431	EPC1	1
GO:0019205	nucleobase-containing compound kinase activity	1/388	42/18367	0.592519486467378	0.770689681698827	GUK1	1
GO:0005246	calcium channel regulator activity	1/388	43/18367	0.601147177558819	0.772903514004196	CALM1	1
GO:0016790	thiolester hydrolase activity	1/388	43/18367	0.601147177558819	0.772903514004196	ABHD17A	1
GO:0018024	histone-lysine N-methyltransferase activity	1/388	43/18367	0.601147177558819	0.772903514004196	KMT2A	1
GO:0030544	Hsp70 protein binding	1/388	43/18367	0.601147177558819	0.772903514004196	SPN	1
GO:0030547	signaling receptor inhibitor activity	1/388	43/18367	0.601147177558819	0.772903514004196	CCL5	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/388	44/18367	0.609592653170431	0.779931327578976	CLK1	1
GO:0008375	acetylglucosaminyltransferase activity	1/388	44/18367	0.609592653170431	0.779931327578976	MGAT4A	1
GO:0008170	N-methyltransferase activity	2/388	97/18367	0.61080643396418	0.779931327578976	KMT2A/PRMT2	2
GO:0043021	ribonucleoprotein complex binding	3/388	149/18367	0.612647956003552	0.780496711073018	DDX5/EIF1/PIM1	3
GO:0140223	general transcription initiation factor activity	1/388	45/18367	0.617859751929906	0.785343374890405	DRAP1	1
GO:0004864	protein phosphatase inhibitor activity	1/388	46/18367	0.625952231803894	0.79202119126207	PPP1R2	1
GO:0140296	general transcription initiation factor binding	1/388	46/18367	0.625952231803894	0.79202119126207	DRAP1	1
GO:0005496	steroid binding	2/388	100/18367	0.62738717160385	0.792040818450109	RORA/CD81	2
GO:0031490	chromatin DNA binding	2/388	103/18367	0.643415002605363	0.810441470550322	ACTB/STAT3	2
GO:0034212	peptide N-acetyltransferase activity	1/388	49/18367	0.649218363120073	0.814076059822474	EPC1	1
GO:0098632	cell-cell adhesion mediator activity	1/388	49/18367	0.649218363120073	0.814076059822474	EMB	1
GO:0005048	signal sequence binding	1/388	50/18367	0.656648392332291	0.819708731367826	NFKBIA	1
GO:0015485	cholesterol binding	1/388	50/18367	0.656648392332291	0.819708731367826	CD81	1
GO:0004601	peroxidase activity	1/388	51/18367	0.663921440526595	0.825111176338556	ALOX5AP	1
GO:0051087	chaperone binding	2/388	107/18367	0.663933545118301	0.825111176338556	HLA-B/DNAJC1	2
GO:0008146	sulfotransferase activity	1/388	52/18367	0.671040815994802	0.828408794967035	CHST12	1
GO:0017046	peptide hormone binding	1/388	52/18367	0.671040815994802	0.828408794967035	PIK3R1	1
GO:0031593	polyubiquitin modification-dependent protein binding	1/388	52/18367	0.671040815994802	0.828408794967035	TNFAIP3	1
GO:0042626	ATPase-coupled transmembrane transporter activity	2/388	109/18367	0.673831898776272	0.830018100479382	TAP1/TAPBP	2
GO:0017069	snRNA binding	1/388	53/18367	0.678009757485057	0.833324768010268	ISG20	1
GO:0015631	tubulin binding	7/388	375/18367	0.682004351901717	0.836183678552028	FYN/ARL4C/SUN2/KIF2A/OFD1/MACF1/CCSER2	7
GO:0008094	ATP-dependent activity, acting on DNA	2/388	111/18367	0.683492606095194	0.836183678552028	ATRX/CHD9	2
GO:0015459	potassium channel regulator activity	1/388	54/18367	0.684831435659994	0.836183678552028	FLNA	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	1/388	55/18367	0.691508954524403	0.841272801026465	ALOX5AP	1
GO:0004843	thiol-dependent deubiquitinase	2/388	113/18367	0.69291818226102	0.841272801026465	TNFAIP3/CYLD	2
GO:0003774	cytoskeletal motor activity	2/388	114/18367	0.69754363882047	0.841272801026465	MYO1F/KIF2A	2
GO:0101005	deubiquitinase activity	2/388	114/18367	0.69754363882047	0.841272801026465	TNFAIP3/CYLD	2
GO:0030374	nuclear receptor coactivator activity	1/388	56/18367	0.698045352823034	0.841272801026465	ETS1	1
GO:0050840	extracellular matrix binding	1/388	56/18367	0.698045352823034	0.841272801026465	LGALS1	1
GO:0004536	deoxyribonuclease activity	1/388	57/18367	0.704443605409166	0.847154163401541	ISG20	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/388	58/18367	0.710706624584548	0.851017803687077	SLC9A3R1	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/388	58/18367	0.710706624584548	0.851017803687077	ALOX5AP	1
GO:0016279	protein-lysine N-methyltransferase activity	1/388	59/18367	0.716837261411311	0.854690580913486	KMT2A	1
GO:0098631	cell adhesion mediator activity	1/388	59/18367	0.716837261411311	0.854690580913486	EMB	1
GO:0001786	phosphatidylserine binding	1/388	60/18367	0.722838306996432	0.858178245327679	TLN1	1
GO:0016278	lysine N-methyltransferase activity	1/388	60/18367	0.722838306996432	0.858178245327679	KMT2A	1
GO:0003697	single-stranded DNA binding	2/388	123/18367	0.736620318921887	0.872683944710006	TERF2IP/SAMHD1	2
GO:0019783	ubiquitin-like protein-specific protease activity	2/388	125/18367	0.744697986198768	0.880384483684137	TNFAIP3/CYLD	2
GO:0008242	omega peptidase activity	2/388	126/18367	0.748656761383106	0.883193388692967	TNFAIP3/CYLD	2
GO:0030145	manganese ion binding	1/388	65/18367	0.750993314447434	0.884063205423079	PIM1	1
GO:0042826	histone deacetylase binding	2/388	127/18367	0.752562764473051	0.884063205423079	IKZF3/PRDM1	2
GO:0008080	N-acetyltransferase activity	1/388	68/18367	0.766497506747772	0.896657460723809	EPC1	1
GO:0016782	transferase activity, transferring sulphur-containing groups	1/388	68/18367	0.766497506747772	0.896657460723809	CHST12	1
GO:0003777	microtubule motor activity	1/388	69/18367	0.771448540540977	0.897115196166862	KIF2A	1
GO:0005518	collagen binding	1/388	69/18367	0.771448540540977	0.897115196166862	CD44	1
GO:0005543	phospholipid binding	8/388	466/18367	0.771711996702677	0.897115196166862	RASGRP1/ARAP2/EPB41/PFN1/BIN2/TLN1/VAMP2/RASA2	8
GO:0001098	basal transcription machinery binding	1/388	70/18367	0.776294860700017	0.898698199731555	DRAP1	1
GO:0001099	basal RNA polymerase II transcription machinery binding	1/388	70/18367	0.776294860700017	0.898698199731555	DRAP1	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/388	71/18367	0.781038676300847	0.900453680528663	GLS	1
GO:0048029	monosaccharide binding	1/388	71/18367	0.781038676300847	0.900453680528663	SLC2A3	1
GO:0000049	tRNA binding	1/388	72/18367	0.78568214993417	0.902079505479973	RPL35A	1
GO:0008235	metalloexopeptidase activity	1/388	72/18367	0.78568214993417	0.902079505479973	LNPEP	1
GO:0033293	monocarboxylic acid binding	1/388	73/18367	0.790227398681125	0.903579689475548	ALOX5AP	1
GO:0070063	RNA polymerase binding	1/388	73/18367	0.790227398681125	0.903579689475548	ZFP36	1
GO:0005254	chloride channel activity	1/388	74/18367	0.794676495068559	0.90495813111889	CLIC1	1
GO:0019905	syntaxin binding	1/388	74/18367	0.794676495068559	0.90495813111889	VAMP2	1
GO:0004842	ubiquitin-protein transferase activity	7/388	433/18367	0.812428171082506	0.923289041678285	RNF213/TRIM22/TNFAIP3/UBE2L6/CBLB/RNF19A/CDC42	7
GO:0004518	nuclease activity	3/388	210/18367	0.823757756641028	0.932830938465703	ISG20/SAMHD1/CNOT6L	3
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/388	82/18367	0.827042504487331	0.932830938465703	PFN1	1
GO:0008017	microtubule binding	4/388	271/18367	0.827511316380865	0.932830938465703	SUN2/KIF2A/MACF1/CCSER2	4
GO:0035091	phosphatidylinositol binding	4/388	271/18367	0.827511316380865	0.932830938465703	ARAP2/EPB41/PFN1/TLN1	4
GO:0008168	methyltransferase activity	3/388	214/18367	0.833347169824571	0.934823667676685	PRDM1/KMT2A/PRMT2	3
GO:0015171	amino acid transmembrane transporter activity	1/388	84/18367	0.834304993732956	0.934823667676685	SLC9A3R1	1
GO:0030165	PDZ domain binding	1/388	84/18367	0.834304993732956	0.934823667676685	SLC9A3R1	1
GO:0016209	antioxidant activity	1/388	86/18367	0.841263283838257	0.934933397883443	ALOX5AP	1
GO:0042562	hormone binding	1/388	86/18367	0.841263283838257	0.934933397883443	PIK3R1	1
GO:0003727	single-stranded RNA binding	1/388	87/18367	0.844632347120941	0.934933397883443	PABPC1	1
GO:0005253	anion channel activity	1/388	87/18367	0.844632347120941	0.934933397883443	CLIC1	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/388	156/18367	0.845011329490968	0.934933397883443	KMT2A/PRMT2	2
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/388	88/18367	0.847930085048571	0.934933397883443	CYBA	1
GO:0000287	magnesium ion binding	3/388	221/18367	0.849052231713594	0.934933397883443	STK4/PRKACB/RPS6KA3	3
GO:0008081	phosphoric diester hydrolase activity	1/388	89/18367	0.851158003807866	0.934933397883443	CCL5	1
GO:0043178	alcohol binding	1/388	89/18367	0.851158003807866	0.934933397883443	CD81	1
GO:0051117	ATPase binding	1/388	89/18367	0.851158003807866	0.934933397883443	LCK	1
GO:0019787	ubiquitin-like protein transferase activity	7/388	458/18367	0.854097000874557	0.935914403029432	RNF213/TRIM22/TNFAIP3/UBE2L6/CBLB/RNF19A/CDC42	7
GO:0016407	acetyltransferase activity	1/388	91/18367	0.857410250606513	0.935914403029432	EPC1	1
GO:0016741	transferase activity, transferring one-carbon groups	3/388	225/18367	0.857437350748662	0.935914403029432	PRDM1/KMT2A/PRMT2	3
GO:0008083	growth factor activity	2/388	162/18367	0.859717349359457	0.935914403029432	GMFG/TGFB1	2
GO:0051213	dioxygenase activity	1/388	92/18367	0.860437435043188	0.935914403029432	ALOX5AP	1
GO:0072341	modified amino acid binding	1/388	93/18367	0.863400514397674	0.936813702049718	TLN1	1
GO:0140097	catalytic activity, acting on DNA	3/388	229/18367	0.865412879220081	0.936813702049718	ISG20/ATRX/CHD9	3
GO:0016410	N-acyltransferase activity	1/388	94/18367	0.866300842755653	0.936813702049718	EPC1	1
GO:1901981	phosphatidylinositol phosphate binding	2/388	173/18367	0.883410594969815	0.953468301727576	ARAP2/PFN1	2
GO:0061630	ubiquitin protein ligase activity	4/388	304/18367	0.887291819178085	0.95580856197176	TRIM22/CBLB/RNF19A/CDC42	4
GO:0008238	exopeptidase activity	1/388	103/18367	0.889789768530559	0.956652583506844	LNPEP	1
GO:0004620	phospholipase activity	1/388	104/18367	0.892131072177632	0.95732526591369	CCL5	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	4/388	310/18367	0.895974843749936	0.958418425558739	PRDM1/IFI16/JUN/ZEB2	4
GO:0015399	primary active transmembrane transporter activity	2/388	181/18367	0.898259289412053	0.958418425558739	TAP1/TAPBP	2
GO:1902936	phosphatidylinositol bisphosphate binding	1/388	107/18367	0.898861476904804	0.958418425558739	PFN1	1
GO:0001217	DNA-binding transcription repressor activity	4/388	313/18367	0.900092364602321	0.958418425558739	PRDM1/IFI16/JUN/ZEB2	4
GO:0061659	ubiquitin-like protein ligase activity	4/388	316/18367	0.904065867883471	0.958418425558739	TRIM22/CBLB/RNF19A/CDC42	4
GO:0008514	organic anion transmembrane transporter activity	2/388	185/18367	0.905005987673431	0.958418425558739	SLC2A3/SLC9A3R1	2
GO:0000149	SNARE binding	1/388	110/18367	0.905172957472143	0.958418425558739	VAMP2	1
GO:0051082	unfolded protein binding	1/388	122/18367	0.926726303635654	0.977829190900271	TAPBP	1
GO:0016757	glycosyltransferase activity	3/388	270/18367	0.927010111086457	0.977829190900271	PARP8/MGAT4A/APRT	3
GO:0009055	electron transfer activity	1/388	126/18367	0.932763744235024	0.98204182883612	CYBA	1
GO:0016298	lipase activity	1/388	129/18367	0.93696385395657	0.984606083818768	CCL5	1
GO:0043177	organic acid binding	1/388	135/18367	0.944595129796362	0.990759553433026	ALOX5AP	1
GO:0020037	heme binding	1/388	139/18367	0.949163406268862	0.993683265849953	CYBA	1
GO:0008194	UDP-glycosyltransferase activity	1/388	143/18367	0.953355906816121	0.995655367206637	MGAT4A	1
GO:0005539	glycosaminoglycan binding	2/388	230/18367	0.956959953293284	0.995655367206637	PTPRC/CD44	2
GO:0008528	G protein-coupled peptide receptor activity	1/388	147/18367	0.95720346862708	0.995655367206637	CXCR4	1
GO:0046906	tetrapyrrole binding	1/388	149/18367	0.959006838060347	0.995655367206637	CYBA	1
GO:0015103	inorganic anion transmembrane transporter activity	1/388	152/18367	0.961570759786737	0.995655367206637	CLIC1	1
GO:0001653	peptide receptor activity	1/388	153/18367	0.962389345853317	0.995655367206637	CXCR4	1
GO:0008509	anion transmembrane transporter activity	3/388	314/18367	0.963537452135455	0.995655367206637	SLC2A3/SLC9A3R1/CLIC1	3
GO:0016853	isomerase activity	1/388	158/18367	0.966228640340959	0.99657867954848	FKBP11	1
GO:0046943	carboxylic acid transmembrane transporter activity	1/388	163/18367	0.969676926135982	0.99657867954848	SLC9A3R1	1
GO:0005342	organic acid transmembrane transporter activity	1/388	164/18367	0.970323232039038	0.99657867954848	SLC9A3R1	1
GO:0008201	heparin binding	1/388	166/18367	0.971574913394934	0.99657867954848	PTPRC	1
GO:0031406	carboxylic acid binding	1/388	176/18367	0.977086228255019	0.998701135089935	ALOX5AP	1
GO:1901681	sulfur compound binding	2/388	265/18367	0.97722369132456	0.998701135089935	PTPRC/CHST12	2
GO:0008237	metallopeptidase activity	1/388	190/18367	0.983058109831889	0.999172909340746	LNPEP	1
GO:0016829	lyase activity	1/388	196/18367	0.985115645300339	0.999172909340746	ALOX5AP	1
GO:0016758	hexosyltransferase activity	1/388	197/18367	0.985433466533263	0.999172909340746	MGAT4A	1
GO:0005244	voltage-gated ion channel activity	1/388	201/18367	0.986638482162637	0.999172909340746	CLIC1	1
GO:0022832	voltage-gated channel activity	1/388	201/18367	0.986638482162637	0.999172909340746	CLIC1	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	1/388	222/18367	0.991511292399664	0.999911707214231	EPC1	1
GO:0016746	acyltransferase activity	1/388	250/18367	0.995367695452876	0.999911707214231	EPC1	1
GO:0022804	active transmembrane transporter activity	2/388	406/18367	0.998447187281789	0.999911707214231	TAP1/TAPBP	2
GO:0022836	gated channel activity	1/388	340/18367	0.999343091339221	0.999911707214231	CLIC1	1
GO:0015267	channel activity	2/388	480/18367	0.999640722369191	0.999911707214231	PRF1/CLIC1	2
GO:0022803	passive transmembrane transporter activity	2/388	481/18367	0.99964782796169	0.999911707214231	PRF1/CLIC1	2
GO:0005216	ion channel activity	1/388	432/18367	0.999911707214231	0.999911707214231	CLIC1	1