ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0042110 T cell activation 48/376 487/18722 5.32401441278885e-20 2.06305558495568e-16 CCL5/IL7R/CD2/PTPRC/HLA-A/CD7/KLRC1/B2M/RAC2/CD3D/LCP1/ZFP36L2/CD3E/HLA-E/XCL1/CORO1A/CD48/CD3G/RUNX3/RORA/FYN/LCK/EOMES/PTPN22/PRDM1/RASGRP1/SPN/MSN/LAT/ITGAL/APBB1IP/IRF1/PTGER4/CD44/FCER1G/WAS/CASP8/RAB29/RAB27A/LAPTM5/LGALS1/CSK/XBP1/CBLB/PTPN6/PYCARD/STAT3/CD81 48 GO:0007159 leukocyte cell-cell adhesion 37/376 371/18722 8.79985417608798e-16 1.70497174661705e-12 CCL5/IL7R/PTPRC/HLA-A/B2M/ETS1/RAC2/CD3E/HLA-E/XCL1/CORO1A/RUNX3/SKAP1/FYN/LCK/PTPN22/RASGRP1/SPN/MSN/TNF/ITGAL/ITGB2/IRF1/ITGA4/SELPLG/CD44/STK10/SEMA4D/LAPTM5/LGALS1/CSK/XBP1/CBLB/PTPN6/PYCARD/CD81/ROCK1 37 GO:0002443 leukocyte mediated immunity 39/376 440/18722 7.20479660203917e-15 8.27304589709225e-12 KLRD1/PRF1/GZMB/IL7R/TRDC/PTPRC/HLA-A/HLA-B/KLRC1/B2M/RAC2/TRBC1/GZMM/HLA-E/XCL1/TRBC2/CORO1A/CD96/HLA-F/SPON2/SH2D1A/NCR3/RASGRP1/LAT/TNF/ITGB2/CCL3/BST2/TYROBP/TGFB1/FCER1G/WAS/BTN3A2/RAB27A/KMT2E/VAMP2/LYST/PTPN6/CD81 39 GO:0034341 response to interferon-gamma 23/376 141/18722 8.53991834538555e-15 8.27304589709225e-12 CCL4/CCL5/XCL2/IFITM1/IFITM2/XCL1/GBP5/TXK/JAK1/IRF1/VIM/CCL3/BST2/GBP4/WAS/STAT1/CCL3L3/GBP2/SP100/ACTR3/CDC42/ACTR2/ACTG1 23 GO:0002683 negative regulation of immune system process 38/376 434/18722 2.41470437327186e-14 1.87139588928569e-11 KLRD1/CST7/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/TSC22D3/HLA-E/XCL1/CD96/RUNX3/HLA-F/FYN/SH2D1A/PTPN22/TBC1D10C/SPN/TNF/IRF1/IFI16/PTGER4/CCL3/BST2/TYROBP/TGFB1/ATM/TNFAIP3/ID2/DGKZ/LAPTM5/ISG15/DUSP1/PIK3R1/CBLB/SAMHD1/LYAR/PTPN6 38 GO:0001819 positive regulation of cytokine production 39/376 467/18722 5.00877644326476e-14 3.23483478627516e-11 CD2/PTPRC/HLA-A/B2M/PYHIN1/CD3E/HLA-E/XCL1/MBP/LTB/HLA-F/SPON2/GBP5/RORA/PTPN22/TXK/RASGRP1/SPN/CYBA/TNF/IRF1/IFI16/PTGER4/CCL3/TYROBP/GPSM3/TGFB1/FCER1G/CASP8/BTN3A2/STAT1/LAPTM5/ISG15/PIK3R1/XBP1/SORL1/PYCARD/STAT3/CD81 39 GO:0001909 leukocyte mediated cytotoxicity 21/376 124/18722 5.92452049762668e-14 3.27964527547191e-11 KLRD1/PRF1/GZMB/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/GZMM/HLA-E/XCL1/CORO1A/HLA-F/SH2D1A/NCR3/RASGRP1/TYROBP/RAB27A/LYST/PTPN6 21 GO:0071346 cellular response to interferon-gamma 20/376 118/18722 2.33897394980497e-13 1.13294050693678e-10 CCL4/CCL5/XCL2/XCL1/GBP5/TXK/JAK1/IRF1/VIM/CCL3/GBP4/WAS/STAT1/CCL3L3/GBP2/SP100/ACTR3/CDC42/ACTR2/ACTG1 20 GO:0045088 regulation of innate immune response 26/376 218/18722 3.13789419411182e-13 1.35103777802037e-10 CCL5/KLRD1/HLA-A/HLA-B/KLRC1/PYHIN1/HLA-E/CD96/HLA-F/GBP5/FYN/SH2D1A/NCR3/PTPN22/TXK/RASGRP1/IRF1/IFI16/TYROBP/TNFAIP3/CASP8/ISG15/SAMHD1/LYAR/PTPN6/PYCARD 26 GO:1903131 mononuclear cell differentiation 35/376 426/18722 1.71363331167785e-12 6.64032908275167e-10 IL7R/CD2/PTPRC/HLA-B/KLRC1/B2M/CD3D/ZFP36L2/CD3E/CD3G/IKZF3/RUNX3/RORA/LCK/EOMES/PTPN22/PRDM1/RASGRP1/ITM2A/SPN/IRF1/ITGA4/IFI16/PTGER4/KLF6/IKZF1/ATM/FCER1G/JUN/ID2/LGALS1/PIK3R1/XBP1/PTPN6/STAT3 35 GO:1903039 positive regulation of leukocyte cell-cell adhesion 26/376 239/18722 2.69131995619662e-12 9.48078620932901e-10 CCL5/IL7R/PTPRC/HLA-A/B2M/ETS1/CD3E/HLA-E/XCL1/CORO1A/RUNX3/SKAP1/FYN/LCK/PTPN22/RASGRP1/TNF/ITGB2/ITGA4/CD44/LGALS1/CSK/XBP1/PTPN6/PYCARD/CD81 26 GO:0009615 response to virus 32/376 367/18722 3.33127542888066e-12 1.07572435724271e-09 CCL4/CCL5/PRF1/IFITM1/PTPRC/IFITM2/XCL1/APOBEC3G/SPON2/ISG20/PTPN22/TNF/CXCR4/DDIT4/IRF1/APOBEC3C/IFI16/BST2/TRIM22/TNFAIP3/RPS15A/CFL1/STAT1/ISG15/IFI44L/LYST/SAMHD1/IRF2/IVNS1ABP/PYCARD/DDX17/HNRNPUL1 32 GO:0001906 cell killing 23/376 188/18722 4.4327169881597e-12 1.24713554373088e-09 GNLY/KLRD1/PRF1/GZMB/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/GZMM/HLA-E/XCL1/CORO1A/HLA-F/SH2D1A/NCR3/RASGRP1/TYROBP/RAB27A/RPL30/LYST/PTPN6 23 GO:0002831 regulation of response to biotic stimulus 30/376 327/18722 4.50578002896319e-12 1.24713554373088e-09 CCL5/KLRD1/HLA-A/HLA-B/KLRC1/PYHIN1/HLA-E/CD96/APOBEC3G/HLA-F/GBP5/FYN/SH2D1A/NCR3/PTPN22/TXK/RASGRP1/CYBA/IRF1/IFI16/TYROBP/TNFAIP3/CASP8/STAT1/ISG15/CARD16/SAMHD1/LYAR/PTPN6/PYCARD 30 GO:0050852 T cell receptor signaling pathway 19/376 123/18722 5.21137091492741e-12 1.33552239171082e-09 PTPRC/HLA-A/CD247/CD3E/SKAP1/FYN/SH2D1A/LCK/PTPN22/TXK/LCP2/RAB29/BTN3A2/DGKZ/LAPTM5/CSK/CBLB/PTPN6/CD81 19 GO:0030098 lymphocyte differentiation 32/376 374/18722 5.51441503674146e-12 1.33552239171082e-09 IL7R/CD2/PTPRC/KLRC1/B2M/CD3D/ZFP36L2/CD3E/CD3G/IKZF3/RUNX3/RORA/LCK/EOMES/PTPN22/PRDM1/RASGRP1/ITM2A/SPN/IRF1/ITGA4/PTGER4/KLF6/IKZF1/ATM/FCER1G/ID2/LGALS1/PIK3R1/XBP1/PTPN6/STAT3 32 GO:0002429 immune response-activating cell surface receptor signaling pathway 28/376 291/18722 7.64706485036366e-12 1.64624312750884e-09 KLRD1/TRDC/PTPRC/HLA-A/CD247/TRBC1/CD3E/TRBC2/SKAP1/FYN/SH2D1A/NCR3/LCK/PTPN22/TXK/LCP2/TYROBP/FCER1G/RAB29/BTN3A2/DGKZ/LAPTM5/PRKCH/CSK/CMTM3/CBLB/PTPN6/CD81 28 GO:0002757 immune response-activating signal transduction 28/376 291/18722 7.64706485036366e-12 1.64624312750884e-09 KLRD1/TRDC/PTPRC/HLA-A/CD247/TRBC1/CD3E/TRBC2/SKAP1/FYN/SH2D1A/NCR3/LCK/PTPN22/TXK/LCP2/TYROBP/FCER1G/RAB29/BTN3A2/DGKZ/LAPTM5/PRKCH/CSK/CMTM3/CBLB/PTPN6/CD81 28 GO:0002228 natural killer cell mediated immunity 15/376 71/18722 8.70323015312783e-12 1.69312134995903e-09 KLRD1/GZMB/HLA-A/HLA-B/KLRC1/HLA-E/CORO1A/CD96/HLA-F/SH2D1A/NCR3/RASGRP1/RAB27A/LYST/PTPN6 15 GO:1903037 regulation of leukocyte cell-cell adhesion 30/376 336/18722 8.96813092986534e-12 1.69312134995903e-09 CCL5/IL7R/PTPRC/HLA-A/B2M/ETS1/CD3E/HLA-E/XCL1/CORO1A/RUNX3/SKAP1/FYN/LCK/PTPN22/RASGRP1/SPN/TNF/ITGB2/IRF1/ITGA4/CD44/LAPTM5/LGALS1/CSK/XBP1/CBLB/PTPN6/PYCARD/CD81 30 GO:0002768 immune response-regulating cell surface receptor signaling pathway 29/376 315/18722 9.52816760582773e-12 1.69312134995903e-09 KLRD1/TRDC/PTPRC/HLA-A/CD247/KLRC1/TRBC1/CD3E/TRBC2/SKAP1/FYN/SH2D1A/NCR3/LCK/PTPN22/TXK/LCP2/TYROBP/FCER1G/RAB29/BTN3A2/DGKZ/LAPTM5/PRKCH/CSK/CMTM3/CBLB/PTPN6/CD81 29 GO:0001913 T cell mediated cytotoxicity 13/376 49/18722 9.61255992234805e-12 1.69312134995903e-09 KLRD1/PRF1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/GZMM/HLA-E/XCL1/HLA-F/RAB27A 13 GO:0022409 positive regulation of cell-cell adhesion 27/376 284/18722 2.41889498760146e-11 3.87138935260819e-09 CCL5/IL7R/PTPRC/HLA-A/B2M/ETS1/CD3E/HLA-E/XCL1/CORO1A/RUNX3/SKAP1/FYN/LCK/PTPN22/RASGRP1/JAK1/TNF/ITGB2/ITGA4/CD44/LGALS1/CSK/XBP1/PTPN6/PYCARD/CD81 27 GO:0002764 immune response-regulating signaling pathway 35/376 468/18722 2.45118351336526e-11 3.87138935260819e-09 KLRD1/TRDC/PTPRC/HLA-A/CD247/KLRC1/TRBC1/CD3E/TRBC2/SKAP1/FYN/SH2D1A/NCR3/LCK/PTPN22/TXK/CYBA/LCP2/IRF1/TYROBP/TNFAIP3/FCER1G/RAB29/BTN3A2/DGKZ/LAPTM5/CYLD/PRKCH/CSK/CMTM3/CBLB/RPS6KA3/PTPN6/CD81/NFKBIA 35 GO:0002449 lymphocyte mediated immunity 30/376 350/18722 2.4976705500698e-11 3.87138935260819e-09 KLRD1/PRF1/GZMB/IL7R/TRDC/PTPRC/HLA-A/HLA-B/KLRC1/B2M/TRBC1/GZMM/HLA-E/XCL1/TRBC2/CORO1A/CD96/HLA-F/SH2D1A/NCR3/RASGRP1/TNF/TGFB1/FCER1G/WAS/BTN3A2/RAB27A/LYST/PTPN6/CD81 30 GO:0002253 activation of immune response 31/376 375/18722 2.89983903322315e-11 4.32187548220758e-09 KLRD1/TRDC/PTPRC/HLA-A/CD247/TRBC1/PYHIN1/CD3E/TRBC2/SKAP1/FYN/SH2D1A/NCR3/LCK/PTPN22/TXK/LCP2/IFI16/TYROBP/FCER1G/RAB29/BTN3A2/DGKZ/LAPTM5/PRKCH/CSK/CMTM3/CBLB/PTPN6/PYCARD/CD81 31 GO:0019221 cytokine-mediated signaling pathway 35/376 472/18722 3.10523938153665e-11 4.456593556835e-09 CCL4/CCL5/XCL2/IL7R/IL2RG/IFITM1/PTPRC/TMSB4X/IFITM2/XCL1/IL2RB/TXK/JAK1/TNF/CXCR4/IRF1/CCL3/CD44/TNFAIP3/FCER1G/CASP8/PLP2/STAT1/IL10RA/CCL3L3/SP100/LAPTM5/CYLD/ISG15/CARD16/SAMHD1/PTPN6/PYCARD/STAT3/NFKBIA 35 GO:0022407 regulation of cell-cell adhesion 34/376 448/18722 3.22146467958659e-11 4.45827701192787e-09 CCL5/IL7R/PTPRC/HLA-A/B2M/ETS1/CD3E/HLA-E/XCL1/CORO1A/MBP/RUNX3/SKAP1/FYN/LCK/PTPN22/RASGRP1/SPN/JAK1/TNF/ITGB2/IRF1/ITGA4/TGFB1/FXYD5/CD44/LAPTM5/LGALS1/CSK/XBP1/CBLB/PTPN6/PYCARD/CD81 34 GO:0042267 natural killer cell mediated cytotoxicity 14/376 68/18722 6.29713735555732e-11 8.36421981295176e-09 KLRD1/GZMB/HLA-A/HLA-B/KLRC1/HLA-E/CORO1A/HLA-F/SH2D1A/NCR3/RASGRP1/RAB27A/LYST/PTPN6 14 GO:0002366 leukocyte activation involved in immune response 26/376 275/18722 6.47552501647878e-11 8.36421981295176e-09 PTPRC/RAC2/LCP1/CORO1A/HLA-F/RORA/EOMES/RASGRP1/ITM2A/SPN/LAT/ITGAL/APBB1IP/ITGB2/PTGER4/CCL3/TYROBP/TGFB1/FCER1G/RAB27A/LGALS1/VAMP2/XBP1/PYCARD/STAT3/CD81 26 GO:0045785 positive regulation of cell adhesion 33/376 437/18722 7.26602830553793e-11 9.08253538192242e-09 CCL5/IL7R/PTPRC/HLA-A/B2M/ETS1/CD3E/HLA-E/XCL1/CORO1A/RUNX3/SKAP1/FYN/LCK/PTPN22/RASGRP1/JAK1/TNF/APBB1IP/ITGB2/ITGA4/STK4/ATM/CD44/FLNA/LGALS1/CSK/XBP1/PTPN6/PYCARD/CDC42/CD81/ROCK1 33 GO:1903706 regulation of hemopoiesis 30/376 367/18722 8.07661164679843e-11 9.78027191604497e-09 IL7R/CD2/PTPRC/HLA-B/B2M/ETS1/ZFP36L2/IKZF3/RUNX3/PRDM1/RASGRP1/TNF/IRF1/CCL3/TYROBP/TGFB1/CASP8/JUN/ZFP36/STAT1/FOS/ID2/EVI2B/ISG15/PIK3R1/XBP1/KLF13/PTPN6/STAT3/NFKBIA 30 GO:0002263 cell activation involved in immune response 26/376 279/18722 8.92082898374445e-11 1.02173596492094e-08 PTPRC/RAC2/LCP1/CORO1A/HLA-F/RORA/EOMES/RASGRP1/ITM2A/SPN/LAT/ITGAL/APBB1IP/ITGB2/PTGER4/CCL3/TYROBP/TGFB1/FCER1G/RAB27A/LGALS1/VAMP2/XBP1/PYCARD/STAT3/CD81 26 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 10/376 28/18722 9.0133897102804e-11 1.02173596492094e-08 HLA-A/HLA-B/B2M/HLA-C/HLA-E/HLA-F/FCER1G/TAP1/TAPBP/LNPEP 10 GO:0050900 leukocyte migration 30/376 369/18722 9.22858290896329e-11 1.02173596492094e-08 CCL4/CCL5/XCL2/RAC2/XCL1/CORO1A/FYN/LCK/SPN/MSN/TNF/ITGAL/CXCR4/ITGB2/ITGA4/SELPLG/PTGER4/CCL3/GPSM3/FCER1G/CCL3L3/STK10/CD99/DUSP1/CKLF/LYST/PYCARD/CDC42/CD81/ROCK1 30 GO:0050851 antigen receptor-mediated signaling pathway 24/376 240/18722 1.1228168173856e-10 1.19229875845535e-08 TRDC/PTPRC/HLA-A/CD247/TRBC1/CD3E/TRBC2/SKAP1/FYN/SH2D1A/LCK/PTPN22/TXK/LCP2/RAB29/BTN3A2/DGKZ/LAPTM5/PRKCH/CSK/CMTM3/CBLB/PTPN6/CD81 24 GO:0050867 positive regulation of cell activation 32/376 420/18722 1.13845300807349e-10 1.19229875845535e-08 CCL5/IL7R/CD2/TRDC/PTPRC/HLA-A/B2M/TRBC1/CD3E/HLA-E/XCL1/TRBC2/CORO1A/PLEK/RUNX3/HLA-F/FYN/LCK/PTPN22/RASGRP1/ITGB2/CCL3/TYROBP/TGFB1/JUND/LGALS1/CSK/XBP1/SH3KBP1/PTPN6/PYCARD/CD81 32 GO:0050863 regulation of T cell activation 28/376 329/18722 1.39252262554936e-10 1.42000662473783e-08 CCL5/IL7R/CD2/PTPRC/HLA-A/B2M/RAC2/CD3E/HLA-E/XCL1/CORO1A/RUNX3/FYN/LCK/PTPN22/PRDM1/RASGRP1/SPN/LAT/IRF1/LAPTM5/LGALS1/CSK/XBP1/CBLB/PTPN6/PYCARD/CD81 28 GO:0006909 phagocytosis 27/376 308/18722 1.54474855164781e-10 1.53484631734238e-08 IL2RG/TRDC/PTPRC/RAC2/TRBC1/TRBC2/CORO1A/IL2RB/SPON2/FYN/CYBA/TNF/ITGAL/ITGB2/TYROBP/ICAM3/CNN2/FCER1G/RAB27A/BIN2/CDC42SE2/CSK/LYST/CDC42SE1/LYAR/PYCARD/CDC42 27 GO:0002703 regulation of leukocyte mediated immunity 23/376 226/18722 1.94778793394542e-10 1.88691956100962e-08 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/RAC2/HLA-E/XCL1/CD96/HLA-F/SH2D1A/NCR3/RASGRP1/TNF/ITGB2/BST2/TYROBP/TGFB1/WAS/PTPN6/CD81 23 GO:0002696 positive regulation of leukocyte activation 31/376 409/18722 2.56307953192308e-10 2.42242272834194e-08 CCL5/IL7R/CD2/TRDC/PTPRC/HLA-A/B2M/TRBC1/CD3E/HLA-E/XCL1/TRBC2/CORO1A/RUNX3/HLA-F/FYN/LCK/PTPN22/RASGRP1/ITGB2/CCL3/TYROBP/TGFB1/JUND/LGALS1/CSK/XBP1/SH3KBP1/PTPN6/PYCARD/CD81 31 GO:0031343 positive regulation of cell killing 13/376 63/18722 2.97250437699649e-10 2.74248915734795e-08 KLRD1/PRF1/PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/HLA-F/SH2D1A/NCR3/RASGRP1/TYROBP 13 GO:0019882 antigen processing and presentation 16/376 106/18722 3.63445399720966e-10 3.27523470678777e-08 HLA-A/HLA-B/B2M/HLA-C/HLA-E/HLA-F/PSMB8/FCER1G/WAS/TAP1/PSME1/RAB27A/RAB8B/TAPBP/LNPEP/PYCARD 16 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 8/376 17/18722 5.10134518094563e-10 4.49266194912825e-08 HLA-A/HLA-B/B2M/HLA-C/HLA-E/HLA-F/TAP1/TAPBP 8 GO:0002456 T cell mediated immunity 16/376 109/18722 5.56658836777533e-10 4.7934510944732e-08 KLRD1/PRF1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/GZMM/HLA-E/XCL1/HLA-F/WAS/BTN3A2/RAB27A/CD81 16 GO:0032103 positive regulation of response to external stimulus 31/376 427/18722 7.37614359805642e-10 6.21359922662362e-08 CCL4/CCL5/KLRD1/XCL2/TMSB4X/ETS1/RAC2/PYHIN1/HLA-E/XCL1/HLA-F/GBP5/FYN/SH2D1A/NCR3/TXK/RASGRP1/ALOX5AP/CYBA/TNF/CXCR4/IFI16/PTGER4/CCL3/TYROBP/GPSM3/TGFB1/FLNA/PYCARD/CD81/NFKBIA 31 GO:0002819 regulation of adaptive immune response 20/376 183/18722 8.65362981356299e-10 7.03149710634877e-08 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/HLA-E/XCL1/CD48/SKAP1/HLA-F/TNF/IRF1/TGFB1/TNFAIP3/WAS/PTPN6/PYCARD/CD81 20 GO:0001910 regulation of leukocyte mediated cytotoxicity 14/376 82/18722 8.70998351238042e-10 7.03149710634877e-08 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/HLA-E/XCL1/HLA-F/SH2D1A/NCR3/RASGRP1/TYROBP 14 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 12/376 56/18722 9.11298071281818e-10 7.20669393105519e-08 KLRD1/PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/HLA-F/SH2D1A/NCR3/RASGRP1/TYROBP 12 GO:0042113 B cell activation 27/376 334/18722 9.40653486710053e-10 7.29006452200291e-08 IL7R/TRDC/PTPRC/TRBC1/ZFP36L2/TRBC2/IKZF3/RASGRP1/TBC1D10C/ITM2A/ITGA4/KLF6/BST2/TYROBP/TGFB1/ATM/TNFAIP3/CASP8/ID2/LAPTM5/LGALS1/PIK3R1/XBP1/SH3KBP1/PTPN6/CD81/SKAP2 27 GO:0031341 regulation of cell killing 15/376 99/18722 1.23005751257355e-09 9.34602521808336e-08 KLRD1/PRF1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/HLA-E/XCL1/HLA-F/SH2D1A/NCR3/RASGRP1/TYROBP 15 GO:0002706 regulation of lymphocyte mediated immunity 19/376 168/18722 1.28635961354248e-09 9.52900594065651e-08 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/HLA-E/XCL1/CD96/HLA-F/SH2D1A/NCR3/RASGRP1/TNF/TGFB1/WAS/PTPN6/CD81 19 GO:0002697 regulation of immune effector process 27/376 339/18722 1.30332210285108e-09 9.52900594065651e-08 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/RAC2/HLA-E/XCL1/CD96/HLA-F/SPON2/SH2D1A/NCR3/PTPN22/RASGRP1/TNF/ITGB2/BST2/TYROBP/TGFB1/WAS/LAPTM5/XBP1/PTPN6/CD81 27 GO:0071356 cellular response to tumor necrosis factor 22/376 229/18722 1.45884381361311e-09 1.0468555143983e-07 CCL4/CCL5/XCL2/TMSB4X/ZFP36L2/XCL1/KLF2/RORA/CYBA/TNF/CCL3/TNFAIP3/CASP8/ZFP36/STAT1/CCL3L3/GBP2/LAPTM5/CYLD/CARD16/PYCARD/NFKBIA 22 GO:0002483 antigen processing and presentation of endogenous peptide antigen 8/376 19/18722 1.5311841176632e-09 1.0787888101718e-07 HLA-A/HLA-B/B2M/HLA-C/HLA-E/HLA-F/TAP1/TAPBP 8 GO:0001914 regulation of T cell mediated cytotoxicity 10/376 39/18722 3.58621328275873e-09 2.48153151262323e-07 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/HLA-E/XCL1/HLA-F 10 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 27/376 356/18722 3.77018897556649e-09 2.49630513882233e-07 KLRD1/PRF1/IL7R/TRDC/PTPRC/HLA-A/HLA-B/KLRC1/B2M/TRBC1/GZMM/HLA-E/XCL1/TRBC2/HLA-F/RORA/SPN/TNF/TGFB1/TNFAIP3/FCER1G/WAS/BTN3A2/RAB27A/PTPN6/STAT3/CD81 27 GO:0002704 negative regulation of leukocyte mediated immunity 12/376 63/18722 3.83764021962593e-09 2.49630513882233e-07 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/XCL1/CD96/HLA-F/BST2/PTPN6 12 GO:0050854 regulation of antigen receptor-mediated signaling pathway 12/376 63/18722 3.83764021962593e-09 2.49630513882233e-07 PTPRC/SH2D1A/LCK/PTPN22/RAB29/DGKZ/LAPTM5/PRKCH/CMTM3/CBLB/PTPN6/CD81 12 GO:0030099 myeloid cell differentiation 28/376 381/18722 3.86524666656361e-09 2.49630513882233e-07 B2M/ETS1/KLF2/TNF/PIP4K2A/IFI16/IKZF1/CCL3/TYROBP/TGFB1/JUNB/CASP8/JUN/ZFP36/STAT1/FOS/ID2/EVI2B/ISG15/PIK3R1/KMT2E/LYAR/KLF13/PTPN6/STAT3/CDC42/CD81/NFKBIA 28 GO:0051607 defense response to virus 23/376 265/18722 4.42441584941922e-09 2.76525990588702e-07 PRF1/IFITM1/PTPRC/IFITM2/APOBEC3G/SPON2/ISG20/PTPN22/DDIT4/IRF1/APOBEC3C/IFI16/BST2/TRIM22/TNFAIP3/STAT1/ISG15/IFI44L/LYST/SAMHD1/IRF2/PYCARD/DDX17 23 GO:0140546 defense response to symbiont 23/376 265/18722 4.42441584941922e-09 2.76525990588702e-07 PRF1/IFITM1/PTPRC/IFITM2/APOBEC3G/SPON2/ISG20/PTPN22/DDIT4/IRF1/APOBEC3C/IFI16/BST2/TRIM22/TNFAIP3/STAT1/ISG15/IFI44L/LYST/SAMHD1/IRF2/PYCARD/DDX17 23 GO:0051251 positive regulation of lymphocyte activation 27/376 362/18722 5.3967072025622e-09 3.3194032396712e-07 CCL5/IL7R/TRDC/PTPRC/HLA-A/B2M/TRBC1/CD3E/HLA-E/XCL1/TRBC2/CORO1A/RUNX3/HLA-F/FYN/LCK/PTPN22/RASGRP1/TYROBP/TGFB1/LGALS1/CSK/XBP1/SH3KBP1/PTPN6/PYCARD/CD81 27 GO:0050792 regulation of viral process 18/376 164/18722 5.69745819141312e-09 3.44963288933216e-07 CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/CXCR4/APOBEC3C/IFI16/DDX5/BST2/TRIM22/ZFP36/STAT1/LGALS1/ISG15/PABPC1/MPHOSPH8 18 GO:0002707 negative regulation of lymphocyte mediated immunity 11/376 53/18722 6.63551412909196e-09 3.95578726926636e-07 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/XCL1/CD96/HLA-F/PTPN6 11 GO:0002181 cytoplasmic translation 17/376 148/18722 7.59606620757263e-09 4.45981159914302e-07 RPL10/RPL28/RPS15A/RPL41/RPL13/RPS4X/RPS27/RPS27A/RPL39/RPL30/RPL35A/RPS29/RPL19/RPL3/RPL17/EIF4A2/TMA7 17 GO:0034612 response to tumor necrosis factor 22/376 253/18722 9.32485494746714e-09 5.39310640618435e-07 CCL4/CCL5/XCL2/TMSB4X/ZFP36L2/XCL1/KLF2/RORA/CYBA/TNF/CCL3/TNFAIP3/CASP8/ZFP36/STAT1/CCL3L3/GBP2/LAPTM5/CYLD/CARD16/PYCARD/NFKBIA 22 GO:0031349 positive regulation of defense response 23/376 278/18722 1.09995652860826e-08 6.26813462993675e-07 CCL5/KLRD1/ETS1/PYHIN1/HLA-E/HLA-F/GBP5/FYN/SH2D1A/NCR3/TXK/RASGRP1/ALOX5AP/CYBA/TNF/IFI16/PTGER4/CCL3/TYROBP/GPSM3/PYCARD/CD81/NFKBIA 23 GO:0002705 positive regulation of leukocyte mediated immunity 16/376 134/18722 1.20260087930698e-08 6.75373682219498e-07 KLRD1/PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/HLA-F/SH2D1A/NCR3/RASGRP1/TNF/ITGB2/TYROBP/TGFB1/CD81 16 GO:0045071 negative regulation of viral genome replication 11/376 56/18722 1.22818542068854e-08 6.78056607432331e-07 CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/APOBEC3C/IFI16/BST2/ISG15/MPHOSPH8 11 GO:0030217 T cell differentiation 22/376 257/18722 1.24237468716634e-08 6.78056607432331e-07 IL7R/CD2/PTPRC/KLRC1/B2M/CD3D/ZFP36L2/CD3E/CD3G/RUNX3/RORA/LCK/EOMES/PTPN22/PRDM1/RASGRP1/SPN/IRF1/PTGER4/FCER1G/XBP1/STAT3 22 GO:0002699 positive regulation of immune effector process 21/376 235/18722 1.26056014823167e-08 6.78426468666349e-07 KLRD1/PTPRC/HLA-A/HLA-B/B2M/RAC2/HLA-E/XCL1/HLA-F/SPON2/SH2D1A/NCR3/PTPN22/RASGRP1/TNF/ITGB2/TYROBP/TGFB1/LAPTM5/XBP1/CD81 21 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 8/376 24/18722 1.3644964473182e-08 7.24304621007949e-07 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/HLA-F 8 GO:0045069 regulation of viral genome replication 13/376 85/18722 1.40800256900026e-08 7.37298642550809e-07 CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/APOBEC3C/IFI16/DDX5/BST2/ISG15/PABPC1/MPHOSPH8 13 GO:0050870 positive regulation of T cell activation 20/376 216/18722 1.54433516514956e-08 7.97906501993939e-07 CCL5/IL7R/PTPRC/HLA-A/B2M/CD3E/HLA-E/XCL1/CORO1A/RUNX3/FYN/LCK/PTPN22/RASGRP1/LGALS1/CSK/XBP1/PTPN6/PYCARD/CD81 20 GO:0045824 negative regulation of innate immune response 12/376 71/18722 1.59361410451494e-08 8.12533507236237e-07 KLRD1/HLA-A/HLA-B/KLRC1/HLA-E/CD96/HLA-F/IFI16/TNFAIP3/ISG15/SAMHD1/LYAR 12 GO:0046640 regulation of alpha-beta T cell proliferation 9/376 35/18722 2.15064673013578e-08 1.08230598432158e-06 PTPRC/HLA-A/CD3E/HLA-E/XCL1/PTPN22/IRF1/CBLB/CD81 9 GO:0016032 viral process 28/376 415/18722 2.47445959887219e-08 1.2292988391833e-06 CCL4/CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/CXCR4/SELPLG/APOBEC3C/IFI16/DDX5/CCL3/BST2/TRIM22/RAB29/CFL1/JUN/ZFP36/STAT1/LGALS1/ISG15/PABPC1/MGAT4A/CDC42/CD81/MPHOSPH8/DDX6 28 GO:0019883 antigen processing and presentation of endogenous antigen 8/376 26/18722 2.79829455184101e-08 1.37258118840303e-06 HLA-A/HLA-B/B2M/HLA-C/HLA-E/HLA-F/TAP1/TAPBP 8 GO:0070661 leukocyte proliferation 24/376 318/18722 3.11360394556002e-08 1.50276842238567e-06 CCL5/IL7R/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/IKZF3/FYN/PTPN22/RASGRP1/SPN/MSN/IRF1/BST2/TYROBP/ATM/TNFAIP3/CBLB/PTPN6/PYCARD/CD81 24 GO:0002715 regulation of natural killer cell mediated immunity 10/376 48/18722 3.14127076679328e-08 1.50276842238567e-06 KLRD1/HLA-A/HLA-B/KLRC1/HLA-E/CD96/HLA-F/SH2D1A/NCR3/RASGRP1 10 GO:0048525 negative regulation of viral process 13/376 92/18722 3.74864961199358e-08 1.75723212463724e-06 CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/APOBEC3C/IFI16/BST2/ZFP36/STAT1/ISG15/MPHOSPH8 13 GO:0048002 antigen processing and presentation of peptide antigen 11/376 62/18722 3.76387784115847e-08 1.75723212463724e-06 HLA-A/HLA-B/B2M/HLA-C/HLA-E/HLA-F/FCER1G/TAP1/TAPBP/LNPEP/PYCARD 11 GO:0002698 negative regulation of immune effector process 14/376 110/18722 4.37628265248263e-08 2.01882086647264e-06 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/XCL1/CD96/HLA-F/TNF/BST2/TGFB1/PTPN6 14 GO:0046633 alpha-beta T cell proliferation 9/376 38/18722 4.70785708818808e-08 2.14622896667398e-06 PTPRC/HLA-A/CD3E/HLA-E/XCL1/PTPN22/IRF1/CBLB/CD81 9 GO:0002716 negative regulation of natural killer cell mediated immunity 7/376 19/18722 5.10140247518243e-08 2.29859704550371e-06 KLRD1/HLA-A/HLA-B/KLRC1/HLA-E/CD96/HLA-F 7 GO:0031342 negative regulation of cell killing 8/376 28/18722 5.37485151213054e-08 2.39397121948343e-06 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/HLA-F 8 GO:1902105 regulation of leukocyte differentiation 22/376 279/18722 5.45263745559805e-08 2.40101933414119e-06 IL7R/CD2/PTPRC/HLA-B/ZFP36L2/IKZF3/RUNX3/PRDM1/RASGRP1/TNF/IRF1/CCL3/TYROBP/TGFB1/CASP8/JUN/FOS/ID2/EVI2B/PIK3R1/XBP1/PTPN6 22 GO:0019079 viral genome replication 15/376 131/18722 6.09143073676309e-08 2.63559120561756e-06 CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/APOBEC3C/IFI16/DDX5/BST2/RAB29/ISG15/PABPC1/CDC42/MPHOSPH8 15 GO:0002708 positive regulation of lymphocyte mediated immunity 14/376 113/18722 6.18647957827908e-08 2.63559120561756e-06 KLRD1/PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/HLA-F/SH2D1A/NCR3/RASGRP1/TNF/TGFB1/CD81 14 GO:0007249 I-kappaB kinase/NF-kappaB signaling 22/376 281/18722 6.18938837964381e-08 2.63559120561756e-06 RORA/FYN/S100A4/TNF/BST2/TRIM22/MTDH/TNFAIP3/FLNA/CASP8/STAT1/LITAF/LGALS1/EEF1D/TERF2IP/REL/CARD16/AKAP13/PYCARD/NFKBIA/CFLAR/ROCK1 22 GO:0070371 ERK1 and ERK2 cascade 24/376 330/18722 6.28503574589694e-08 2.64722972992942e-06 CCL4/CCL5/XCL2/PTPRC/ZFP36L2/XCL1/PTPN22/RASGRP1/TBC1D10C/TNF/PTGER4/CCL3/TGFB1/CD44/CCL3L3/GLIPR2/YWHAZ/DUSP1/CSK/RAP1B/SLC9A3R1/PTPN6/PYCARD/CFLAR 24 GO:0031334 positive regulation of protein-containing complex assembly 20/376 237/18722 7.30628947307238e-08 3.04428728044682e-06 LCP1/CORO1A/PLEK/SKAP1/GBP5/EVL/MSN/TNF/GMFG/TGFB1/ATM/WAS/PFN1/ISG15/RAP1B/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 20 GO:0002285 lymphocyte activation involved in immune response 18/376 194/18722 7.90607061345992e-08 3.25915144969757e-06 PTPRC/LCP1/CORO1A/HLA-F/RORA/EOMES/ITM2A/SPN/ITGAL/APBB1IP/PTGER4/TGFB1/FCER1G/RAB27A/LGALS1/XBP1/STAT3/CD81 18 GO:0071674 mononuclear cell migration 18/376 196/18722 9.24682499112732e-08 3.77173124638088e-06 CCL4/CCL5/XCL2/XCL1/SPN/MSN/TNF/ITGAL/CXCR4/ITGA4/CCL3/CCL3L3/STK10/CD99/DUSP1/CKLF/PYCARD/CDC42 18 GO:0046651 lymphocyte proliferation 22/376 288/18722 9.55481240022815e-08 3.81462572772023e-06 CCL5/IL7R/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/IKZF3/FYN/PTPN22/RASGRP1/SPN/MSN/IRF1/TYROBP/ATM/CBLB/PTPN6/PYCARD/CD81 22 GO:0050856 regulation of T cell receptor signaling pathway 9/376 41/18722 9.59390440559842e-08 3.81462572772023e-06 SH2D1A/LCK/PTPN22/RAB29/DGKZ/LAPTM5/CBLB/PTPN6/CD81 9 GO:0072676 lymphocyte migration 14/376 117/18722 9.6473115178473e-08 3.81462572772023e-06 CCL4/CCL5/XCL2/XCL1/SPN/MSN/ITGAL/ITGA4/CCL3/CCL3L3/STK10/CD99/CKLF/PYCARD 14 GO:0046631 alpha-beta T cell activation 16/376 156/18722 1.05059915470327e-07 4.11219366108602e-06 PTPRC/HLA-A/CD3E/HLA-E/XCL1/RUNX3/RORA/EOMES/PTPN22/PRDM1/SPN/IRF1/PTGER4/CBLB/STAT3/CD81 16 GO:0046641 positive regulation of alpha-beta T cell proliferation 7/376 21/18722 1.13709495182495e-07 4.39651037582946e-06 PTPRC/HLA-A/CD3E/HLA-E/XCL1/PTPN22/CD81 7 GO:0032943 mononuclear cell proliferation 22/376 291/18722 1.14592915602265e-07 4.39651037582946e-06 CCL5/IL7R/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/IKZF3/FYN/PTPN22/RASGRP1/SPN/MSN/IRF1/TYROBP/ATM/CBLB/PTPN6/PYCARD/CD81 22 GO:0042098 T cell proliferation 18/376 199/18722 1.1651347035008e-07 4.42636958437803e-06 CCL5/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/FYN/PTPN22/RASGRP1/SPN/MSN/IRF1/CBLB/PTPN6/PYCARD/CD81 18 GO:0070663 regulation of leukocyte proliferation 20/376 245/18722 1.26041786544094e-07 4.74006449672264e-06 CCL5/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/IKZF3/PTPN22/SPN/IRF1/BST2/TYROBP/ATM/TNFAIP3/CBLB/PTPN6/PYCARD/CD81 20 GO:0002709 regulation of T cell mediated immunity 12/376 85/18722 1.27217214879782e-07 4.74006449672264e-06 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/HLA-E/XCL1/HLA-F/WAS/CD81 12 GO:0032970 regulation of actin filament-based process 26/376 396/18722 1.35645837633649e-07 5.00597734124182e-06 TMSB4X/RAC2/CORO1A/PLEK/ARHGDIB/GPR65/EVL/GMFG/PTGER4/BST2/CNN2/WAS/FLNA/TMSB10/PFN1/PIK3R1/AKAP13/ABRACL/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2/ACTG1/ROCK1 26 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 20/376 249/18722 1.64102722118453e-07 5.99903819065101e-06 RORA/FYN/S100A4/TNF/BST2/TRIM22/MTDH/TNFAIP3/FLNA/CASP8/STAT1/LITAF/LGALS1/EEF1D/TERF2IP/REL/CARD16/AKAP13/PYCARD/CFLAR 20 GO:0035456 response to interferon-beta 8/376 32/18722 1.69552221133405e-07 6.14032576534529e-06 IFITM1/IFITM2/PYHIN1/IRF1/IFI16/BST2/XAF1/STAT1 8 GO:0042269 regulation of natural killer cell mediated cytotoxicity 9/376 44/18722 1.84082303622327e-07 6.60480487533813e-06 KLRD1/HLA-A/HLA-B/KLRC1/HLA-E/HLA-F/SH2D1A/NCR3/RASGRP1 9 GO:0030101 natural killer cell activation 12/376 88/18722 1.88127638274287e-07 6.6880238377327e-06 CD2/PTPRC/HLA-E/CORO1A/HLA-F/NCR3/PTPN22/PRDM1/RASGRP1/TYROBP/CASP8/RAB27A 12 GO:0034109 homotypic cell-cell adhesion 12/376 90/18722 2.42016504645986e-07 8.52558141366542e-06 CCL5/PLEK/JAK1/MYL12A/FLNA/ACTB/LGALS1/TLN1/CD99/PTPN6/ACTG1/CLIC1 12 GO:0002832 negative regulation of response to biotic stimulus 13/376 108/18722 2.5883029779666e-07 9.03574237803655e-06 KLRD1/HLA-A/HLA-B/KLRC1/HLA-E/CD96/HLA-F/IFI16/TNFAIP3/ISG15/CARD16/SAMHD1/LYAR 13 GO:0045637 regulation of myeloid cell differentiation 18/376 210/18722 2.61989837914631e-07 9.06438055284997e-06 B2M/ETS1/TNF/CCL3/TYROBP/TGFB1/CASP8/JUN/ZFP36/STAT1/FOS/ID2/EVI2B/ISG15/PIK3R1/KLF13/STAT3/NFKBIA 18 GO:0032956 regulation of actin cytoskeleton organization 24/376 357/18722 2.70417969096708e-07 9.27318256858181e-06 TMSB4X/RAC2/CORO1A/PLEK/ARHGDIB/GPR65/EVL/GMFG/PTGER4/BST2/WAS/FLNA/TMSB10/PFN1/PIK3R1/AKAP13/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2/ACTG1/ROCK1 24 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 16/376 168/18722 2.93072691864286e-07 9.96190071029921e-06 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/B2M/HLA-E/XCL1/HLA-F/TNF/TGFB1/TNFAIP3/WAS/PTPN6/CD81 16 GO:1903900 regulation of viral life cycle 15/376 148/18722 3.07848008332082e-07 1.03731394111897e-05 CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/APOBEC3C/IFI16/DDX5/BST2/TRIM22/LGALS1/ISG15/PABPC1/MPHOSPH8 15 GO:0007015 actin filament organization 27/376 441/18722 3.1452287549383e-07 1.05066908839534e-05 TMSB4X/RAC2/LCP1/CORO1A/PLEK/GPR65/EVL/GMFG/WIPF1/PTGER4/TPM3/WAS/FLNA/CFL1/TMSB10/PFN1/MYO1F/PIK3R1/SH3KBP1/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2/ACTG1/ROCK1 27 GO:0022604 regulation of cell morphogenesis 22/376 309/18722 3.24021384488474e-07 1.06405327533291e-05 RAC2/CORO1A/FYN/MSN/CXCR4/ITGB2/MYL12A/CCL3/CD44/FLNA/CFL1/EPB41/FMNL1/SEMA4D/CDC42SE2/CDC42SE1/SLC9A3R1/SH3KBP1/CDC42EP3/CDC42/MACF1/ACTR2 22 GO:0070372 regulation of ERK1 and ERK2 cascade 22/376 309/18722 3.24021384488474e-07 1.06405327533291e-05 CCL4/CCL5/XCL2/PTPRC/XCL1/PTPN22/RASGRP1/TBC1D10C/TNF/CCL3/TGFB1/CD44/CCL3L3/GLIPR2/YWHAZ/DUSP1/CSK/RAP1B/SLC9A3R1/PTPN6/PYCARD/CFLAR 22 GO:2000401 regulation of lymphocyte migration 10/376 61/18722 3.43386249999874e-07 1.11816951155421e-05 CCL4/CCL5/XCL2/XCL1/SPN/MSN/ITGA4/CCL3/STK10/PYCARD 10 GO:2000403 positive regulation of lymphocyte migration 8/376 35/18722 3.59930017363781e-07 1.16227401440388e-05 CCL4/CCL5/XCL2/XCL1/SPN/ITGA4/CCL3/PYCARD 8 GO:0002237 response to molecule of bacterial origin 24/376 363/18722 3.6629695532985e-07 1.17305843132493e-05 CCL5/B2M/CD96/SPON2/PTPN22/TNF/VIM/PTGER4/CCL3/TGFB1/MTDH/TNFAIP3/CASP8/JUN/ZFP36/IL10RA/FOS/LITAF/JUND/XBP1/CARD16/RPS6KA3/PYCARD/NFKBIA 24 GO:0032609 interferon-gamma production 13/376 112/18722 3.97245994424378e-07 1.24489621271614e-05 CD2/HLA-A/CD3E/XCL1/CD96/PTPN22/TXK/RASGRP1/TNF/BTN3A2/LAPTM5/ISG15/PYCARD 13 GO:0032649 regulation of interferon-gamma production 13/376 112/18722 3.97245994424378e-07 1.24489621271614e-05 CD2/HLA-A/CD3E/XCL1/CD96/PTPN22/TXK/RASGRP1/TNF/BTN3A2/LAPTM5/ISG15/PYCARD 13 GO:0045089 positive regulation of innate immune response 14/376 131/18722 3.98366788069164e-07 1.24489621271614e-05 CCL5/KLRD1/PYHIN1/HLA-E/HLA-F/GBP5/FYN/SH2D1A/NCR3/TXK/RASGRP1/IFI16/TYROBP/PYCARD 14 GO:0050777 negative regulation of immune response 17/376 194/18722 4.12643777858666e-07 1.27919571136187e-05 KLRD1/IL7R/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/XCL1/CD96/HLA-F/FYN/IFI16/TNFAIP3/ISG15/SAMHD1/LYAR/PTPN6 17 GO:0002718 regulation of cytokine production involved in immune response 12/376 96/18722 4.95402179965851e-07 1.52355829156165e-05 HLA-A/B2M/HLA-E/XCL1/CD96/HLA-F/SPON2/TNF/BST2/TGFB1/LAPTM5/CD81 12 GO:0032496 response to lipopolysaccharide 23/376 343/18722 5.03404678417181e-07 1.53597884162723e-05 CCL5/CD96/SPON2/PTPN22/TNF/VIM/PTGER4/CCL3/TGFB1/MTDH/TNFAIP3/CASP8/JUN/ZFP36/IL10RA/FOS/LITAF/JUND/XBP1/CARD16/RPS6KA3/PYCARD/NFKBIA 23 GO:0008360 regulation of cell shape 15/376 154/18722 5.16060081771636e-07 1.56229126317585e-05 RAC2/CORO1A/FYN/MSN/ITGB2/MYL12A/CCL3/EPB41/FMNL1/SEMA4D/CDC42SE2/CDC42SE1/SLC9A3R1/SH3KBP1/CDC42EP3 15 GO:0050864 regulation of B cell activation 17/376 198/18722 5.50933430543925e-07 1.65493569252536e-05 TRDC/PTPRC/TRBC1/ZFP36L2/TRBC2/IKZF3/TBC1D10C/TYROBP/TGFB1/ATM/TNFAIP3/ID2/LAPTM5/XBP1/SH3KBP1/PTPN6/CD81 17 GO:0043254 regulation of protein-containing complex assembly 26/376 427/18722 5.8056154089272e-07 1.73051997766099e-05 TMSB4X/LCP1/CORO1A/PLEK/SKAP1/GBP5/EVL/MSN/TNF/GMFG/PTGER4/TGFB1/ATM/WAS/TMSB10/PFN1/ISG15/RAP1B/SORL1/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2/ATF7IP 26 GO:0002367 cytokine production involved in immune response 12/376 98/18722 6.21432778793822e-07 1.83820764719547e-05 HLA-A/B2M/HLA-E/XCL1/CD96/HLA-F/SPON2/TNF/BST2/TGFB1/LAPTM5/CD81 12 GO:0002274 myeloid leukocyte activation 18/376 223/18722 6.37171896608336e-07 1.87048568133129e-05 CCL5/CST7/CD2/PTPRC/RAC2/RORA/RASGRP1/LAT/TNF/ITGB2/LCP2/CCL3/TYROBP/FCER1G/JUND/KMT2E/VAMP2/PYCARD 18 GO:0050670 regulation of lymphocyte proliferation 18/376 225/18722 7.26097984294272e-07 2.11551104446639e-05 CCL5/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/IKZF3/PTPN22/SPN/IRF1/TYROBP/ATM/CBLB/PTPN6/PYCARD/CD81 18 GO:0072678 T cell migration 10/376 66/18722 7.34861376700056e-07 2.12506554829307e-05 CCL5/XCL2/XCL1/SPN/MSN/ITGAL/ITGA4/CCL3/CD99/PYCARD 10 GO:0036037 CD8-positive, alpha-beta T cell activation 7/376 27/18722 7.82621558470502e-07 2.24641373264681e-05 HLA-A/HLA-E/XCL1/RUNX3/EOMES/PTPN22/IRF1 7 GO:0032640 tumor necrosis factor production 16/376 181/18722 8.05003703807956e-07 2.27692653449331e-05 CD2/PTPRC/HLA-E/SPON2/PTPN22/RASGRP1/SPN/CYBA/CCL3/TYROBP/TNFAIP3/ZFP36/PIK3R1/PTPN6/PYCARD/STAT3 16 GO:0032680 regulation of tumor necrosis factor production 16/376 181/18722 8.05003703807956e-07 2.27692653449331e-05 CD2/PTPRC/HLA-E/SPON2/PTPN22/RASGRP1/SPN/CYBA/CCL3/TYROBP/TNFAIP3/ZFP36/PIK3R1/PTPN6/PYCARD/STAT3 16 GO:0032944 regulation of mononuclear cell proliferation 18/376 227/18722 8.26164252228894e-07 2.31984527346881e-05 CCL5/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/IKZF3/PTPN22/SPN/IRF1/TYROBP/ATM/CBLB/PTPN6/PYCARD/CD81 18 GO:0110053 regulation of actin filament organization 20/376 277/18722 8.98648101519816e-07 2.50522402402107e-05 TMSB4X/CORO1A/PLEK/GPR65/EVL/GMFG/PTGER4/WAS/FLNA/TMSB10/PFN1/PIK3R1/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2/ACTG1/ROCK1 20 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 6/376 18/18722 9.54360938166753e-07 2.64153473956869e-05 KLRD1/HLA-A/HLA-B/KLRC1/HLA-E/HLA-F 6 GO:0032760 positive regulation of tumor necrosis factor production 12/376 103/18722 1.06908864676663e-06 2.91740739874698e-05 CD2/PTPRC/HLA-E/SPON2/RASGRP1/SPN/CYBA/CCL3/TYROBP/PIK3R1/PYCARD/STAT3 12 GO:0045639 positive regulation of myeloid cell differentiation 12/376 103/18722 1.06908864676663e-06 2.91740739874698e-05 ETS1/TNF/TYROBP/TGFB1/CASP8/JUN/STAT1/FOS/ID2/EVI2B/ISG15/STAT3 12 GO:1901653 cellular response to peptide 23/376 359/18722 1.10917199664049e-06 3.00562341746987e-05 KLF2/FYN/PTPN22/CYBA/PIP4K2A/ITGA4/VIM/NR4A2/STAT1/RAB8B/UCP2/PIK3R1/CSK/VAMP2/XBP1/RAP1B/SORL1/STAT3/LEPROTL1/SRSF5/CFLAR/ROCK1/APRT 23 GO:0002700 regulation of production of molecular mediator of immune response 15/376 164/18722 1.15581787873814e-06 3.05344704168854e-05 PTPRC/HLA-A/B2M/HLA-E/XCL1/CD96/HLA-F/SPON2/PTPN22/TNF/BST2/TGFB1/LAPTM5/XBP1/CD81 15 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 16/376 186/18722 1.1583399100083e-06 3.05344704168854e-05 FYN/S100A4/TNF/BST2/TRIM22/MTDH/FLNA/CASP8/LITAF/LGALS1/EEF1D/TERF2IP/REL/CARD16/AKAP13/CFLAR 16 GO:0071706 tumor necrosis factor superfamily cytokine production 16/376 186/18722 1.1583399100083e-06 3.05344704168854e-05 CD2/PTPRC/HLA-E/SPON2/PTPN22/RASGRP1/SPN/CYBA/CCL3/TYROBP/TNFAIP3/ZFP36/PIK3R1/PTPN6/PYCARD/STAT3 16 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 16/376 186/18722 1.1583399100083e-06 3.05344704168854e-05 CD2/PTPRC/HLA-E/SPON2/PTPN22/RASGRP1/SPN/CYBA/CCL3/TYROBP/TNFAIP3/ZFP36/PIK3R1/PTPN6/PYCARD/STAT3 16 GO:0002695 negative regulation of leukocyte activation 16/376 187/18722 1.24388156757228e-06 3.25678450969093e-05 CST7/PTPRC/XCL1/RUNX3/HLA-F/PTPN22/TBC1D10C/SPN/IRF1/TYROBP/ATM/TNFAIP3/ID2/LAPTM5/CBLB/PTPN6 16 GO:0002685 regulation of leukocyte migration 17/376 210/18722 1.25472044978791e-06 3.26311526371018e-05 CCL4/CCL5/XCL2/RAC2/XCL1/SPN/MSN/TNF/ITGA4/PTGER4/CCL3/GPSM3/STK10/CD99/DUSP1/PYCARD/CD81 17 GO:0001916 positive regulation of T cell mediated cytotoxicity 7/376 29/18722 1.32869444957363e-06 3.43246066139855e-05 PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/HLA-F 7 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation 6/376 19/18722 1.3712902828198e-06 3.51903963306404e-05 HLA-A/HLA-E/XCL1/RUNX3/PTPN22/IRF1 6 GO:0002833 positive regulation of response to biotic stimulus 15/376 168/18722 1.56804250285803e-06 3.9974767753782e-05 CCL5/KLRD1/PYHIN1/HLA-E/HLA-F/GBP5/FYN/SH2D1A/NCR3/TXK/RASGRP1/CYBA/IFI16/TYROBP/PYCARD 15 GO:0042060 wound healing 25/376 422/18722 1.58054982816558e-06 4.00302652558275e-05 ETS1/PLEK/LCK/TXK/TNF/CXCR4/MYL12A/TGFB1/CNN2/CD44/TNFAIP3/FCER1G/WAS/FLNA/ACTB/RAB27A/DGKZ/TLN1/XBP1/PTPN6/MACF1/ACTG1/CFLAR/FGFR1OP2/CLIC1 25 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 12/376 107/18722 1.61263964250806e-06 4.05777832124593e-05 CD2/PTPRC/HLA-E/SPON2/RASGRP1/SPN/CYBA/CCL3/TYROBP/PIK3R1/PYCARD/STAT3 12 GO:0032729 positive regulation of interferon-gamma production 10/376 72/18722 1.67828018827642e-06 4.19570047069104e-05 CD2/HLA-A/CD3E/PTPN22/TXK/RASGRP1/TNF/BTN3A2/ISG15/PYCARD 10 GO:0019058 viral life cycle 21/376 317/18722 1.92505295779218e-06 4.78178218682352e-05 CCL5/IFITM1/IFITM2/APOBEC3G/ISG20/TNF/CXCR4/SELPLG/APOBEC3C/IFI16/DDX5/BST2/TRIM22/RAB29/LGALS1/ISG15/PABPC1/CDC42/CD81/MPHOSPH8/DDX6 21 GO:0042129 regulation of T cell proliferation 15/376 171/18722 1.959102806797e-06 4.83536520785884e-05 CCL5/PTPRC/HLA-A/RAC2/CD3E/HLA-E/XCL1/CORO1A/PTPN22/SPN/IRF1/CBLB/PTPN6/PYCARD/CD81 15 GO:0002821 positive regulation of adaptive immune response 12/376 112/18722 2.62633317539579e-06 6.44116522446752e-05 PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/SKAP1/HLA-F/TNF/TGFB1/PYCARD/CD81 12 GO:0031663 lipopolysaccharide-mediated signaling pathway 9/376 60/18722 2.89198747718935e-06 7.0480826881187e-05 CCL5/PTPN22/TNF/CCL3/TGFB1/MTDH/TNFAIP3/CARD16/NFKBIA 9 GO:0050764 regulation of phagocytosis 11/376 95/18722 3.19948626134292e-06 7.74875578918989e-05 IL2RG/PTPRC/IL2RB/CYBA/TNF/CNN2/FCER1G/RAB27A/CSK/LYAR/PYCARD 11 GO:0034113 heterotypic cell-cell adhesion 9/376 61/18722 3.33309153574136e-06 8.02219236086818e-05 CD2/PTPRC/MBP/SKAP1/LCK/TNF/ITGB2/ITGA4/CD44 9 GO:0071675 regulation of mononuclear cell migration 12/376 115/18722 3.47408494680136e-06 8.30992541287361e-05 CCL4/CCL5/XCL2/XCL1/SPN/MSN/TNF/ITGA4/CCL3/STK10/DUSP1/PYCARD 12 GO:0051250 negative regulation of lymphocyte activation 14/376 157/18722 3.54700671703003e-06 8.37097969091212e-05 XCL1/RUNX3/HLA-F/PTPN22/TBC1D10C/SPN/IRF1/TYROBP/ATM/TNFAIP3/ID2/LAPTM5/CBLB/PTPN6 14 GO:0001818 negative regulation of cytokine production 22/376 357/18722 3.58306606448831e-06 8.37097969091212e-05 PTPRC/TMSB4X/XCL1/KLF2/CD96/HLA-F/SRGN/PTPN22/TNF/PTGER4/BST2/TYROBP/TGFB1/TNFAIP3/ZFP36/LAPTM5/CYLD/CSK/REL/CARD16/PTPN6/PYCARD 22 GO:0050860 negative regulation of T cell receptor signaling pathway 6/376 22/18722 3.58340852451488e-06 8.37097969091212e-05 SH2D1A/PTPN22/DGKZ/LAPTM5/CBLB/PTPN6 6 GO:0070486 leukocyte aggregation 5/376 13/18722 3.58601968694558e-06 8.37097969091212e-05 RAC2/MSN/CD44/STK10/SEMA4D 5 GO:0032731 positive regulation of interleukin-1 beta production 9/376 62/18722 3.83079284244822e-06 8.88881572723765e-05 PYHIN1/GBP5/TNF/IFI16/CCL3/TYROBP/CASP8/PYCARD/STAT3 9 GO:0019884 antigen processing and presentation of exogenous antigen 8/376 47/18722 3.89681311995284e-06 8.98818502370074e-05 HLA-A/B2M/HLA-E/HLA-F/FCER1G/TAP1/PSME1/LNPEP 8 GO:1901216 positive regulation of neuron death 11/376 97/18722 3.93240267043505e-06 9.01660375617505e-05 FYN/TNF/DDIT4/ITGB2/CCL3/TYROBP/CASP8/JUN/FOS/CDC42/MCL1 11 GO:0002702 positive regulation of production of molecular mediator of immune response 12/376 117/18722 4.16527903636774e-06 9.4943860387794e-05 PTPRC/HLA-A/B2M/HLA-E/XCL1/HLA-F/SPON2/PTPN22/TGFB1/LAPTM5/XBP1/CD81 12 GO:0031348 negative regulation of defense response 18/376 258/18722 5.11812608364191e-06 0.000115980927333991 KLRD1/CST7/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/CD96/HLA-F/RORA/FYN/IFI16/PTGER4/TNFAIP3/ZFP36/ISG15/SAMHD1/LYAR 18 GO:0030218 erythrocyte differentiation 12/376 120/18722 5.42900310188901e-06 0.000122310389650116 B2M/ETS1/KLF2/IKZF1/ZFP36/STAT1/ID2/ISG15/KMT2E/LYAR/KLF13/STAT3 12 GO:0050866 negative regulation of cell activation 16/376 210/18722 5.64128487640171e-06 0.000126358259514778 CST7/PTPRC/XCL1/RUNX3/HLA-F/PTPN22/TBC1D10C/SPN/IRF1/TYROBP/ATM/TNFAIP3/ID2/LAPTM5/CBLB/PTPN6 16 GO:0071677 positive regulation of mononuclear cell migration 9/376 65/18722 5.72482917168761e-06 0.000127492603679825 CCL4/CCL5/XCL2/XCL1/SPN/TNF/ITGA4/CCL3/PYCARD 9 GO:0060337 type I interferon signaling pathway 8/376 50/18722 6.3128169338123e-06 0.000138802625541862 IFITM1/IFITM2/JAK1/STAT1/SP100/ISG15/SAMHD1/PTPN6 8 GO:0032635 interleukin-6 production 14/376 165/18722 6.3401457344283e-06 0.000138802625541862 HLA-B/KLF2/MBP/SPON2/PTPN22/CYBA/TNF/TYROBP/TNFAIP3/CSK/XBP1/PTPN6/PYCARD/STAT3 14 GO:0032675 regulation of interleukin-6 production 14/376 165/18722 6.3401457344283e-06 0.000138802625541862 HLA-B/KLF2/MBP/SPON2/PTPN22/CYBA/TNF/TYROBP/TNFAIP3/CSK/XBP1/PTPN6/PYCARD/STAT3 14 GO:0050766 positive regulation of phagocytosis 9/376 66/18722 6.51271882352776e-06 0.00014177969348972 IL2RG/PTPRC/IL2RB/CYBA/TNF/FCER1G/RAB27A/LYAR/PYCARD 9 GO:0051651 maintenance of location in cell 16/376 213/18722 6.75986665332593e-06 0.000146337895428145 PTPRC/TMSB4X/XCL1/CORO1A/SRGN/LCK/SYNE1/CYBA/CALM1/CCL3/TMSB10/SP100/SUN2/SORL1/PTPN6/VPS13C 16 GO:0071375 cellular response to peptide hormone stimulus 19/376 290/18722 6.96969300378438e-06 0.000150042002164803 FYN/CYBA/PIP4K2A/NR4A2/STAT1/RAB8B/UCP2/PIK3R1/CSK/VAMP2/XBP1/RAP1B/SORL1/STAT3/LEPROTL1/SRSF5/CFLAR/ROCK1/APRT 19 GO:0030168 platelet activation 12/376 123/18722 7.0180114594195e-06 0.000150247482901937 PLEK/LCK/TXK/MYL12A/FCER1G/FLNA/ACTB/DGKZ/TLN1/PTPN6/ACTG1/CLIC1 12 GO:1901214 regulation of neuron death 20/376 319/18722 7.71704041388174e-06 0.000164305118702152 CCL5/CORO1A/HLA-F/FYN/TNF/DDIT4/ITGB2/CCL3/TYROBP/NR4A2/CASP8/RAB29/JUN/FOS/REL/BTG2/SORL1/STAT3/CDC42/MCL1 20 GO:0046634 regulation of alpha-beta T cell activation 11/376 104/18722 7.77991560919631e-06 0.000164738650194731 PTPRC/HLA-A/CD3E/HLA-E/XCL1/RUNX3/PTPN22/PRDM1/IRF1/CBLB/CD81 11 GO:0009612 response to mechanical stimulus 16/376 216/18722 8.07269120865907e-06 0.000170009121921488 ETS1/TXNIP/FYN/CYBA/CXCR4/IRF1/PTGER4/CNN2/CASP8/JUN/STAT1/FOS/JUND/BTG2/FOSB/NFKBIA 16 GO:0032231 regulation of actin filament bundle assembly 11/376 105/18722 8.53630463973749e-06 0.000177345583707873 PLEK/GPR65/EVL/PTGER4/WAS/FLNA/PFN1/PIK3R1/CDC42/ACTG1/ROCK1 11 GO:0071357 cellular response to type I interferon 8/376 52/18722 8.54442981612732e-06 0.000177345583707873 IFITM1/IFITM2/JAK1/STAT1/SP100/ISG15/SAMHD1/PTPN6 8 GO:0070374 positive regulation of ERK1 and ERK2 cascade 16/376 217/18722 8.55835462022508e-06 0.000177345583707873 CCL4/CCL5/XCL2/PTPRC/XCL1/PTPN22/RASGRP1/TNF/CCL3/TGFB1/CD44/CCL3L3/GLIPR2/RAP1B/PYCARD/CFLAR 16 GO:0002478 antigen processing and presentation of exogenous peptide antigen 7/376 38/18722 9.19525549653427e-06 0.000189529867282289 HLA-A/B2M/HLA-E/HLA-F/FCER1G/TAP1/LNPEP 7 GO:0002710 negative regulation of T cell mediated immunity 6/376 26/18722 1.03305665852866e-05 0.000209586102188407 KLRD1/IL7R/PTPRC/KLRC1/XCL1/HLA-F 6 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 6/376 26/18722 1.03305665852866e-05 0.000209586102188407 KLRD1/HLA-E/HLA-F/SH2D1A/NCR3/RASGRP1 6 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 6/376 26/18722 1.03305665852866e-05 0.000209586102188407 PTPRC/LCK/RAB29/PRKCH/CMTM3/CD81 6 GO:0001959 regulation of cytokine-mediated signaling pathway 13/376 150/18722 1.07761264669087e-05 0.000217486927392038 CCL5/PTPRC/TXK/CXCR4/TNFAIP3/CASP8/LAPTM5/CYLD/ISG15/CARD16/SAMHD1/PTPN6/PYCARD 13 GO:0034101 erythrocyte homeostasis 12/376 129/18722 1.145957927247e-05 0.000230082226325499 B2M/ETS1/KLF2/IKZF1/ZFP36/STAT1/ID2/ISG15/KMT2E/LYAR/KLF13/STAT3 12 GO:0043434 response to peptide hormone 23/376 414/18722 1.18536008478239e-05 0.000236766511779988 FYN/CYBA/BTG1/PIP4K2A/NR4A2/STAT1/RAB8B/JUND/UCP2/PIK3R1/CSK/VAMP2/XBP1/RAP1B/BTG2/SORL1/VPS13C/STAT3/LEPROTL1/SRSF5/CFLAR/ROCK1/APRT 23 GO:1903829 positive regulation of cellular protein localization 18/376 276/18722 1.29236507347751e-05 0.000256816136396171 GZMB/CD247/RAC2/PYHIN1/FYN/MSN/TNF/ITGB2/TYROBP/TGFB1/FLNA/EPB41/TOMM7/ABHD17A/PIK3R1/PRKCH/SORL1/CD81 18 GO:0002719 negative regulation of cytokine production involved in immune response 6/376 27/18722 1.30585508786626e-05 0.000258126170839802 XCL1/CD96/HLA-F/TNF/BST2/TGFB1 6 GO:0030866 cortical actin cytoskeleton organization 7/376 40/18722 1.31228014594686e-05 0.000258126170839802 LCP1/PLEK/TNF/EPB41/FMNL1/TLN1/ROCK1 7 GO:0032611 interleukin-1 beta production 11/376 110/18722 1.3358450077519e-05 0.000260120573117518 PYHIN1/GBP5/TNF/IFI16/CCL3/TYROBP/TNFAIP3/CASP8/CARD16/PYCARD/STAT3 11 GO:0032651 regulation of interleukin-1 beta production 11/376 110/18722 1.3358450077519e-05 0.000260120573117518 PYHIN1/GBP5/TNF/IFI16/CCL3/TYROBP/TNFAIP3/CASP8/CARD16/PYCARD/STAT3 11 GO:0002711 positive regulation of T cell mediated immunity 8/376 56/18722 1.5039317681269e-05 0.000289604511005889 PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/HLA-F/CD81 8 GO:0032732 positive regulation of interleukin-1 production 9/376 73/18722 1.5096802896307e-05 0.000289604511005889 PYHIN1/GBP5/TNF/IFI16/CCL3/TYROBP/CASP8/PYCARD/STAT3 9 GO:0043299 leukocyte degranulation 9/376 73/18722 1.5096802896307e-05 0.000289604511005889 RAC2/CORO1A/HLA-F/RASGRP1/LAT/ITGB2/CCL3/RAB27A/VAMP2 9 GO:0033157 regulation of intracellular protein transport 16/376 229/18722 1.67854387048252e-05 0.000320411699414766 GZMB/RAC2/LCP1/FYN/ITGB2/TGFB1/FLNA/RAB29/SP100/TOMM7/PIK3R1/VAMP2/SORL1/CDC42/CD81/GCC2 16 GO:0007265 Ras protein signal transduction 20/376 337/18722 1.72121912969791e-05 0.000326947261155853 RAC2/ARHGDIB/GPR65/RASGRP1/LAT/DOK2/ARHGEF1/WAS/CYTH1/CFL1/JUN/CDC42SE2/ARHGEF3/RAP1B/CDC42SE1/AKAP13/RASA2/CDC42EP3/CDC42/ROCK1 20 GO:0045185 maintenance of protein location 10/376 93/18722 1.74052670527288e-05 0.000329001999167434 TMSB4X/SRGN/SYNE1/FLNA/TMSB10/SP100/SUN2/SORL1/VPS13C/NFKBIA 10 GO:1902107 positive regulation of leukocyte differentiation 13/376 157/18722 1.76131097677004e-05 0.000329714011351879 IL7R/PTPRC/RUNX3/RASGRP1/TNF/TYROBP/TGFB1/CASP8/JUN/FOS/ID2/EVI2B/XBP1 13 GO:1903708 positive regulation of hemopoiesis 13/376 157/18722 1.76131097677004e-05 0.000329714011351879 IL7R/PTPRC/RUNX3/RASGRP1/TNF/TYROBP/TGFB1/CASP8/JUN/FOS/ID2/EVI2B/XBP1 13 GO:0002687 positive regulation of leukocyte migration 12/376 135/18722 1.81889029090522e-05 0.000338855763329698 CCL4/CCL5/XCL2/RAC2/XCL1/SPN/TNF/ITGA4/CCL3/GPSM3/CD99/PYCARD 12 GO:0002286 T cell activation involved in immune response 11/376 114/18722 1.87708189244918e-05 0.000348023556614382 LCP1/RORA/EOMES/SPN/ITGAL/APBB1IP/PTGER4/FCER1G/RAB27A/STAT3/CD81 11 GO:0002763 positive regulation of myeloid leukocyte differentiation 8/376 58/18722 1.95970920719596e-05 0.000359899202743334 TNF/TYROBP/TGFB1/CASP8/JUN/FOS/ID2/EVI2B 8 GO:0034340 response to type I interferon 8/376 58/18722 1.95970920719596e-05 0.000359899202743334 IFITM1/IFITM2/JAK1/STAT1/SP100/ISG15/SAMHD1/PTPN6 8 GO:2000406 positive regulation of T cell migration 6/376 29/18722 2.02563337123363e-05 0.000370251382713695 CCL5/XCL2/XCL1/SPN/ITGA4/PYCARD 6 GO:0007266 Rho protein signal transduction 12/376 137/18722 2.10934226386042e-05 0.000383741843777424 ARHGDIB/GPR65/ARHGEF1/WAS/CFL1/CDC42SE2/ARHGEF3/CDC42SE1/AKAP13/CDC42EP3/CDC42/ROCK1 12 GO:0036230 granulocyte activation 7/376 43/18722 2.15375747612642e-05 0.000388449806781626 CCL5/ITGB2/CCL3/TYROBP/FCER1G/KMT2E/VAMP2 7 GO:0090316 positive regulation of intracellular protein transport 13/376 160/18722 2.1552698956916e-05 0.000388449806781626 GZMB/RAC2/FYN/ITGB2/TGFB1/FLNA/RAB29/TOMM7/PIK3R1/VAMP2/SORL1/CDC42/CD81 13 GO:0071222 cellular response to lipopolysaccharide 15/376 209/18722 2.24464382803102e-05 0.000402684946000935 CCL5/SPON2/PTPN22/TNF/VIM/CCL3/TGFB1/MTDH/TNFAIP3/ZFP36/LITAF/XBP1/CARD16/PYCARD/NFKBIA 15 GO:0060759 regulation of response to cytokine stimulus 13/376 162/18722 2.45895742614084e-05 0.000439099540382294 CCL5/PTPRC/TXK/CXCR4/TNFAIP3/CASP8/LAPTM5/CYLD/ISG15/CARD16/SAMHD1/PTPN6/PYCARD 13 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 6/376 30/18722 2.48945824446373e-05 0.000440486333209907 SH2D1A/PTPN22/DGKZ/LAPTM5/CBLB/PTPN6 6 GO:2000637 positive regulation of gene silencing by miRNA 6/376 30/18722 2.48945824446373e-05 0.000440486333209907 DDX5/TGFB1/ZFP36/STAT3/DDX6/TNRC6B 6 GO:0031295 T cell costimulation 7/376 44/18722 2.51743235562742e-05 0.00044341138082074 CD3E/FYN/LCK/LGALS1/CSK/PTPN6/CD81 7 GO:0030183 B cell differentiation 12/376 141/18722 2.8135148329867e-05 0.000493319908498799 PTPRC/ZFP36L2/IKZF3/ITM2A/ITGA4/KLF6/ATM/ID2/LGALS1/PIK3R1/XBP1/PTPN6 12 GO:0030865 cortical cytoskeleton organization 8/376 61/18722 2.85711461130688e-05 0.000498708068415053 RAC2/LCP1/PLEK/TNF/EPB41/FMNL1/TLN1/ROCK1 8 GO:0140131 positive regulation of lymphocyte chemotaxis 5/376 19/18722 2.9331965645731e-05 0.000509692228148913 CCL4/CCL5/XCL2/XCL1/CCL3 5 GO:0042742 defense response to bacterium 20/376 350/18722 2.957794322863e-05 0.00051031343289164 GNLY/IL7R/TRDC/HLA-A/TRBC1/HLA-E/TRBC2/SPON2/SPN/CYBA/TNF/PLAC8/GBP4/FCER1G/GBP2/ISG15/RPL39/RPL30/LYST/PYCARD 20 GO:0002444 myeloid leukocyte mediated immunity 10/376 99/18722 3.01706722438513e-05 0.00051031343289164 RAC2/HLA-E/SPON2/RASGRP1/LAT/ITGB2/CCL3/TYROBP/KMT2E/VAMP2 10 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 10/376 99/18722 3.01706722438513e-05 0.00051031343289164 CRIP1/TNF/DDIT4/IFI16/ATM/CDKN2D/CD44/PIK3R1/PYCARD/MCL1 10 GO:0030838 positive regulation of actin filament polymerization 10/376 99/18722 3.01706722438513e-05 0.00051031343289164 CORO1A/EVL/GMFG/WAS/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 10 GO:0033209 tumor necrosis factor-mediated signaling pathway 10/376 99/18722 3.01706722438513e-05 0.00051031343289164 TMSB4X/TNF/TNFAIP3/CASP8/STAT1/LAPTM5/CYLD/CARD16/PYCARD/NFKBIA 10 GO:0002717 positive regulation of natural killer cell mediated immunity 6/376 31/18722 3.0350306386851e-05 0.00051031343289164 KLRD1/HLA-E/HLA-F/SH2D1A/NCR3/RASGRP1 6 GO:0060148 positive regulation of posttranscriptional gene silencing 6/376 31/18722 3.0350306386851e-05 0.00051031343289164 DDX5/TGFB1/ZFP36/STAT3/DDX6/TNRC6B 6 GO:0001915 negative regulation of T cell mediated cytotoxicity 4/376 10/18722 3.05529590789317e-05 0.00051031343289164 KLRD1/IL7R/PTPRC/KLRC1 4 GO:0035747 natural killer cell chemotaxis 4/376 10/18722 3.05529590789317e-05 0.00051031343289164 CCL4/CCL5/XCL1/CCL3 4 GO:0070555 response to interleukin-1 12/376 143/18722 3.23654229067216e-05 0.000538266153491614 CCL4/CCL5/XCL2/ETS1/XCL1/KLF2/RORA/CYBA/CCL3/CCL3L3/GBP2/PYCARD 12 GO:0110020 regulation of actomyosin structure organization 10/376 100/18722 3.29333527381264e-05 0.000545370691710427 GPR65/EVL/PTGER4/WAS/PFN1/PIK3R1/AKAP13/CDC42/ACTG1/ROCK1 10 GO:1902903 regulation of supramolecular fiber organization 21/376 382/18722 3.31434712908311e-05 0.000546514686178598 TMSB4X/CORO1A/PLEK/GPR65/EVL/GMFG/PTGER4/WAS/FLNA/TMSB10/PFN1/PIK3R1/AKAP13/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2/ACTG1/ROCK1 21 GO:0031294 lymphocyte costimulation 7/376 46/18722 3.39708298339921e-05 0.000557783752570844 CD3E/FYN/LCK/LGALS1/CSK/PTPN6/CD81 7 GO:0008154 actin polymerization or depolymerization 15/376 217/18722 3.47820276519816e-05 0.000568693490090416 TMSB4X/CORO1A/PLEK/EVL/GMFG/WIPF1/WAS/CFL1/TMSB10/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 15 GO:0060968 regulation of gene silencing 9/376 81/18722 3.52344021431087e-05 0.000573669362624143 TNF/DDX5/TGFB1/ZFP36/STAT3/MPHOSPH8/DDX6/TNRC6B/ATF7IP 9 GO:1990266 neutrophil migration 11/376 122/18722 3.5487082267393e-05 0.000575365873582208 CCL4/CCL5/XCL2/RAC2/XCL1/ITGB2/CCL3/FCER1G/CCL3L3/CD99/CKLF 11 GO:0051235 maintenance of location 19/376 326/18722 3.57298773679893e-05 0.000576888645003994 PTPRC/TMSB4X/XCL1/CORO1A/SRGN/LCK/SYNE1/CYBA/TNF/CALM1/CCL3/FLNA/TMSB10/SP100/SUN2/SORL1/PTPN6/VPS13C/NFKBIA 19 GO:0042102 positive regulation of T cell proliferation 10/376 101/18722 3.59095970187004e-05 0.000577384599367072 CCL5/PTPRC/HLA-A/CD3E/HLA-E/XCL1/CORO1A/PTPN22/PYCARD/CD81 10 GO:0019835 cytolysis 6/376 32/18722 3.67264394264139e-05 0.000588078317261793 GZMA/PRF1/GZMB/GZMH/GZMM/TGFB1 6 GO:0048872 homeostasis of number of cells 17/376 272/18722 3.85131664636083e-05 0.000614150288257128 IL7R/B2M/ETS1/TSC22D3/KLF2/CORO1A/LAT/IKZF1/TNFAIP3/ZFP36/STAT1/ID2/ISG15/KMT2E/LYAR/KLF13/STAT3 17 GO:0045646 regulation of erythrocyte differentiation 7/376 47/18722 3.9233782758949e-05 0.000623077492585767 B2M/ETS1/ZFP36/STAT1/ISG15/KLF13/STAT3 7 GO:0071216 cellular response to biotic stimulus 16/376 246/18722 4.02679049133253e-05 0.000636890332812798 CCL5/TXNIP/SPON2/PTPN22/TNF/VIM/CCL3/TGFB1/MTDH/TNFAIP3/ZFP36/LITAF/XBP1/CARD16/PYCARD/NFKBIA 16 GO:0032507 maintenance of protein location in cell 8/376 64/18722 4.07532765947539e-05 0.000641946938230372 TMSB4X/SRGN/SYNE1/TMSB10/SP100/SUN2/SORL1/VPS13C 8 GO:0030593 neutrophil chemotaxis 10/376 103/18722 4.25568804903931e-05 0.000665040755807259 CCL4/CCL5/XCL2/RAC2/XCL1/ITGB2/CCL3/FCER1G/CCL3L3/CKLF 10 GO:0043410 positive regulation of MAPK cascade 24/376 480/18722 4.25626083716646e-05 0.000665040755807259 CCL4/CCL5/XCL2/PTPRC/XCL1/PTPN22/RASGRP1/TNF/CCL3/TGFB1/CD44/CCL3L3/LAPTM5/GLIPR2/CSK/RAP1B/AKAP13/TAOK3/PYCARD/CDC42/GADD45B/CD81/CFLAR/ROCK1 24 GO:0071219 cellular response to molecule of bacterial origin 15/376 221/18722 4.29411659169811e-05 0.000668261116177918 CCL5/SPON2/PTPN22/TNF/VIM/CCL3/TGFB1/MTDH/TNFAIP3/ZFP36/LITAF/XBP1/CARD16/PYCARD/NFKBIA 15 GO:0032102 negative regulation of response to external stimulus 22/376 420/18722 4.47041764717916e-05 0.00069291473531277 KLRD1/CST7/PTPRC/HLA-A/HLA-B/KLRC1/HLA-E/CD96/HLA-F/RORA/FYN/TNF/IFI16/PTGER4/TNFAIP3/ZFP36/SEMA4D/ISG15/DUSP1/CARD16/SAMHD1/LYAR 22 GO:0097530 granulocyte migration 12/376 148/18722 4.54371129797844e-05 0.000700104191866812 CCL4/CCL5/XCL2/RAC2/XCL1/ITGB2/PTGER4/CCL3/FCER1G/CCL3L3/CD99/CKLF 12 GO:0002720 positive regulation of cytokine production involved in immune response 8/376 65/18722 4.56695499172894e-05 0.000700104191866812 HLA-A/B2M/HLA-E/XCL1/HLA-F/SPON2/LAPTM5/CD81 8 GO:0070997 neuron death 20/376 361/18722 4.5710028527046e-05 0.000700104191866812 CCL5/CORO1A/HLA-F/FYN/TNF/DDIT4/ITGB2/CCL3/TYROBP/NR4A2/CASP8/RAB29/JUN/FOS/REL/BTG2/SORL1/STAT3/CDC42/MCL1 20 GO:0010921 regulation of phosphatase activity 9/376 84/18722 4.71609202980121e-05 0.000719482543916523 PTPRC/PLEK/TNF/CALM1/SEMA4D/PPP1R15A/PPP1R2/PPP1R12A/ROCK1 9 GO:0051098 regulation of binding 20/376 363/18722 4.93691131214638e-05 0.000750216915081067 GZMA/B2M/TMSB4X/PYHIN1/HOPX/CALM1/ITGA4/STK4/IFI16/TGFB1/JUN/EPB41/ACTB/SP100/CBLB/CARD16/SORL1/CDC42/NFKBIA/ROCK1 20 GO:0060964 regulation of gene silencing by miRNA 7/376 49/18722 5.1772940288822e-05 0.000783672436012443 TNF/DDX5/TGFB1/ZFP36/STAT3/DDX6/TNRC6B 7 GO:0050869 negative regulation of B cell activation 6/376 34/18722 5.26909299575774e-05 0.000794464410838959 TBC1D10C/TYROBP/ATM/TNFAIP3/ID2/LAPTM5 6 GO:0032612 interleukin-1 production 11/376 128/18722 5.52923024444975e-05 0.000827249698735242 PYHIN1/GBP5/TNF/IFI16/CCL3/TYROBP/TNFAIP3/CASP8/CARD16/PYCARD/STAT3 11 GO:0032652 regulation of interleukin-1 production 11/376 128/18722 5.52923024444975e-05 0.000827249698735242 PYHIN1/GBP5/TNF/IFI16/CCL3/TYROBP/TNFAIP3/CASP8/CARD16/PYCARD/STAT3 11 GO:0046635 positive regulation of alpha-beta T cell activation 8/376 67/18722 5.6993047580609e-05 0.000846161147030115 PTPRC/HLA-A/CD3E/HLA-E/XCL1/RUNX3/PTPN22/CD81 8 GO:0070527 platelet aggregation 8/376 67/18722 5.6993047580609e-05 0.000846161147030115 PLEK/MYL12A/FLNA/ACTB/TLN1/PTPN6/ACTG1/CLIC1 8 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 10/376 107/18722 5.90454900123629e-05 0.000869966820524358 PTPRC/HLA-A/HLA-B/B2M/HLA-E/XCL1/HLA-F/TNF/TGFB1/CD81 10 GO:0007229 integrin-mediated signaling pathway 10/376 107/18722 5.90454900123629e-05 0.000869966820524358 PLEK/TXK/LAT/ITGAL/ITGB2/ITGA4/FLNA/TLN1/ISG15/CDC42 10 GO:0032388 positive regulation of intracellular transport 14/376 202/18722 6.13868261927193e-05 0.000901037695063588 GZMB/RAC2/FYN/MSN/ITGB2/TGFB1/FLNA/RAB29/TOMM7/PIK3R1/VAMP2/SORL1/CDC42/CD81 14 GO:0032814 regulation of natural killer cell activation 6/376 35/18722 6.25248689073459e-05 0.000914278743456473 HLA-E/HLA-F/PTPN22/PRDM1/RASGRP1/TYROBP 6 GO:0030595 leukocyte chemotaxis 15/376 230/18722 6.7704044918978e-05 0.000986290128049022 CCL4/CCL5/XCL2/RAC2/XCL1/CORO1A/CXCR4/ITGB2/CCL3/GPSM3/FCER1G/CCL3L3/DUSP1/CKLF/LYST 15 GO:0045010 actin nucleation 7/376 52/18722 7.65748104929159e-05 0.00110719175619421 CORO1A/EVL/GMFG/WAS/ACTR3/ARPC5L/ACTR2 7 GO:0060147 regulation of posttranscriptional gene silencing 7/376 52/18722 7.65748104929159e-05 0.00110719175619421 TNF/DDX5/TGFB1/ZFP36/STAT3/DDX6/TNRC6B 7 GO:0045123 cellular extravasation 8/376 70/18722 7.8289301024035e-05 0.00112411258869229 SPN/TNF/ITGAL/ITGA4/SELPLG/PTGER4/CD99/ROCK1 8 GO:0097193 intrinsic apoptotic signaling pathway 17/376 288/18722 7.83252642443661e-05 0.00112411258869229 CRIP1/LCK/TNF/DDIT4/IFI16/DDX5/ATM/CDKN2D/CD44/CYLD/PIK3R1/XBP1/SLC9A3R1/IVNS1ABP/PYCARD/PPP1R15A/MCL1 17 GO:0002262 myeloid cell homeostasis 12/376 157/18722 8.06749835924056e-05 0.0011493219169874 B2M/ETS1/KLF2/IKZF1/ZFP36/STAT1/ID2/ISG15/KMT2E/LYAR/KLF13/STAT3 12 GO:0051017 actin filament bundle assembly 12/376 157/18722 8.06749835924056e-05 0.0011493219169874 LCP1/PLEK/GPR65/EVL/PTGER4/WAS/FLNA/PFN1/PIK3R1/CDC42/ACTG1/ROCK1 12 GO:0002573 myeloid leukocyte differentiation 14/376 208/18722 8.41280459688343e-05 0.00119412519461257 TNF/IFI16/CCL3/TYROBP/TGFB1/JUNB/CASP8/JUN/FOS/ID2/EVI2B/PIK3R1/CDC42/CD81 14 GO:0043368 positive T cell selection 6/376 37/18722 8.65716428627047e-05 0.00122200098468697 PTPRC/CD3D/CD3E/CD3G/SPN/STAT3 6 GO:0060966 regulation of gene silencing by RNA 7/376 53/18722 8.67226505261722e-05 0.00122200098468697 TNF/DDX5/TGFB1/ZFP36/STAT3/DDX6/TNRC6B 7 GO:1902905 positive regulation of supramolecular fiber organization 14/376 209/18722 8.85564690849333e-05 0.00123739791295757 CORO1A/PLEK/GPR65/EVL/GMFG/WAS/FLNA/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2 14 GO:0002275 myeloid cell activation involved in immune response 9/376 91/18722 8.87733212392785e-05 0.00123739791295757 RAC2/RASGRP1/LAT/ITGB2/CCL3/TYROBP/FCER1G/VAMP2/PYCARD 9 GO:0051492 regulation of stress fiber assembly 9/376 91/18722 8.87733212392785e-05 0.00123739791295757 GPR65/EVL/PTGER4/WAS/PFN1/PIK3R1/CDC42/ACTG1/ROCK1 9 GO:0045936 negative regulation of phosphate metabolic process 22/376 441/18722 9.15334881422348e-05 0.00127129844641993 PTPRC/PLEK/PTPN22/TNF/CALM1/DDIT4/PIP4K2A/TGFB1/CDKN2D/TNFAIP3/SEMA4D/DUSP1/CSK/TERF2IP/CBLB/SORL1/PTPN6/PYCARD/PPP1R15A/STAT3/GADD45B/ROCK1 22 GO:0071347 cellular response to interleukin-1 10/376 113/18722 9.3812950178099e-05 0.00129830422121476 CCL4/CCL5/XCL2/XCL1/KLF2/RORA/CCL3/CCL3L3/GBP2/PYCARD 10 GO:0010563 negative regulation of phosphorus metabolic process 22/376 442/18722 9.45838011546489e-05 0.00130431398389418 PTPRC/PLEK/PTPN22/TNF/CALM1/DDIT4/PIP4K2A/TGFB1/CDKN2D/TNFAIP3/SEMA4D/DUSP1/CSK/TERF2IP/CBLB/SORL1/PTPN6/PYCARD/PPP1R15A/STAT3/GADD45B/ROCK1 22 GO:0043433 negative regulation of DNA-binding transcription factor activity 13/376 185/18722 9.72548202079883e-05 0.00133163733348253 TMSB4X/XCL1/EOMES/TNFAIP3/FLNA/ID2/SP100/CYLD/COMMD6/PIM1/PYCARD/PRMT2/NFKBIA 13 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7/376 54/18722 9.79397780754895e-05 0.00133163733348253 KLRD1/IL7R/PTPRC/KLRC1/XCL1/HLA-F/PTPN6 7 GO:0006968 cellular defense response 7/376 54/18722 9.79397780754895e-05 0.00133163733348253 GNLY/PRF1/KLRG1/SH2D1A/SPN/LSP1/TYROBP 7 GO:1902743 regulation of lamellipodium organization 7/376 54/18722 9.79397780754895e-05 0.00133163733348253 RAC2/CD44/WAS/PIK3R1/ACTR3/CDC42/ACTR2 7 GO:0035458 cellular response to interferon-beta 5/376 24/18722 9.87095483230483e-05 0.00133741083829305 IFITM2/PYHIN1/IRF1/IFI16/STAT1 5 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 4/376 13/18722 9.91636788458945e-05 0.0013385946897431 ZFP36/PABPC1/BTG2/TNRC6B 4 GO:0032535 regulation of cellular component size 20/376 382/18722 9.94878117796166e-05 0.0013385946897431 IL7R/TMSB4X/CORO1A/PLEK/EVL/MSN/GMFG/WAS/TMSB10/PFN1/SEMA4D/SLC9A3R1/PYCARD/ACTR3/PPP1R15A/ARPC5L/CDC42EP3/MACF1/ACTR2/HP1BP3 20 GO:0061572 actin filament bundle organization 12/376 161/18722 0.000102688591372662 0.00137687990162306 LCP1/PLEK/GPR65/EVL/PTGER4/WAS/FLNA/PFN1/PIK3R1/CDC42/ACTG1/ROCK1 12 GO:0008064 regulation of actin polymerization or depolymerization 13/376 187/18722 0.000108408238633325 0.00144855836104874 TMSB4X/CORO1A/PLEK/EVL/GMFG/WAS/TMSB10/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 13 GO:0051100 negative regulation of binding 12/376 162/18722 0.000108936512741562 0.00145061507516685 GZMA/B2M/TMSB4X/ITGA4/IFI16/JUN/ACTB/SP100/CARD16/SORL1/NFKBIA/ROCK1 12 GO:0061614 pri-miRNA transcription by RNA polymerase II 7/376 55/18722 0.00011030960848866 0.00146386894826561 ETS1/TNF/DDX5/TGFB1/JUN/FOS/STAT3 7 GO:0030832 regulation of actin filament length 13/376 188/18722 0.000114387663017306 0.00150941917293741 TMSB4X/CORO1A/PLEK/EVL/GMFG/WAS/TMSB10/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 13 GO:0050727 regulation of inflammatory response 20/376 386/18722 0.000114521093378993 0.00150941917293741 CCL5/CST7/PTPRC/TMSB4X/ETS1/HLA-E/XCL1/RORA/FYN/ALOX5AP/TNF/PTGER4/CCL3/GPSM3/TNFAIP3/ZFP36/CYLD/PYCARD/CD81/NFKBIA 20 GO:0002701 negative regulation of production of molecular mediator of immune response 6/376 39/18722 0.000117455146104312 0.00154284302086172 XCL1/CD96/HLA-F/TNF/BST2/TGFB1 6 GO:0033622 integrin activation 5/376 25/18722 0.000121366258201306 0.00158348232501704 PLEK/SKAP1/PTGER4/TLN1/RAP1B 5 GO:1901623 regulation of lymphocyte chemotaxis 5/376 25/18722 0.000121366258201306 0.00158348232501704 CCL4/CCL5/XCL2/XCL1/CCL3 5 GO:0033077 T cell differentiation in thymus 8/376 75/18722 0.000128248630816216 0.00166673754347873 IL7R/PTPRC/B2M/CD3D/ZFP36L2/CD3E/CD3G/RASGRP1 8 GO:0071900 regulation of protein serine/threonine kinase activity 19/376 359/18722 0.000128607619483907 0.00166673754347873 PTPN22/RASGRP1/CCND2/TNF/CALM1/STK4/TGFB1/CDKN2D/TNFAIP3/ACTB/DUSP1/CSK/SORL1/AKAP13/CCNL1/PTPN6/TAOK3/PYCARD/DAZAP2 19 GO:0007596 blood coagulation 14/376 217/18722 0.000131903041890378 0.00170374762441738 PLEK/LCK/TXK/MYL12A/FCER1G/WAS/FLNA/ACTB/RAB27A/DGKZ/TLN1/PTPN6/ACTG1/CLIC1 14 GO:0043922 negative regulation by host of viral transcription 4/376 14/18722 0.000136634575975568 0.0017473893792255 CCL4/CCL5/CCL3/JUN 4 GO:0045059 positive thymic T cell selection 4/376 14/18722 0.000136634575975568 0.0017473893792255 PTPRC/CD3D/CD3E/CD3G 4 GO:0061043 regulation of vascular wound healing 4/376 14/18722 0.000136634575975568 0.0017473893792255 TNF/CXCR4/TNFAIP3/XBP1 4 GO:0061756 leukocyte adhesion to vascular endothelial cell 7/376 57/18722 0.000138861559479935 0.00177002810192351 ETS1/SPN/TNF/ITGB2/ITGA4/SELPLG/ROCK1 7 GO:0007162 negative regulation of cell adhesion 17/376 303/18722 0.000144883372090618 0.00184073136672506 PTPRC/XCL1/ARHGDIB/MBP/RUNX3/PTPN22/SPN/IRF1/TGFB1/FXYD5/SEMA4D/LAPTM5/LGALS1/DUSP1/PIK3R1/CBLB/PTPN6 17 GO:0034114 regulation of heterotypic cell-cell adhesion 5/376 26/18722 0.000147803327633691 0.00187169246594952 MBP/SKAP1/LCK/TNF/CD44 5 GO:1990778 protein localization to cell periphery 18/376 333/18722 0.000148346230040575 0.00187244834334602 SKAP1/TNF/MYL12A/TGFB1/FLNA/RAB29/EPB41/ACTB/RAB8B/PIK3R1/PRKCH/CSK/VAMP2/SLC9A3R1/MACF1/CD81/VAMP5/ROCK1 18 GO:0097529 myeloid leukocyte migration 14/376 220/18722 0.000152352542972083 0.00191677306498968 CCL4/CCL5/XCL2/RAC2/XCL1/ITGB2/PTGER4/CCL3/FCER1G/CCL3L3/CD99/DUSP1/CKLF/CD81 14 GO:0002761 regulation of myeloid leukocyte differentiation 10/376 120/18722 0.000154938030490762 0.00194038990326777 TNF/CCL3/TYROBP/TGFB1/CASP8/JUN/FOS/ID2/EVI2B/PIK3R1 10 GO:0043666 regulation of phosphoprotein phosphatase activity 7/376 58/18722 0.000155231192261422 0.00194038990326777 PTPRC/TNF/CALM1/PPP1R15A/PPP1R2/PPP1R12A/ROCK1 7 GO:1901654 response to ketone 13/376 194/18722 0.000156594555534746 0.00195113795079466 TXNIP/KLF2/GNG2/CYBA/MSN/CALM1/DDIT4/PTGER4/TGFB1/FOS/DUSP1/FOSB/CFLAR 13 GO:0007599 hemostasis 14/376 222/18722 0.000167460799640685 0.00207319680066343 PLEK/LCK/TXK/MYL12A/FCER1G/WAS/FLNA/ACTB/RAB27A/DGKZ/TLN1/PTPN6/ACTG1/CLIC1 14 GO:0050817 coagulation 14/376 222/18722 0.000167460799640685 0.00207319680066343 PLEK/LCK/TXK/MYL12A/FCER1G/WAS/FLNA/ACTB/RAB27A/DGKZ/TLN1/PTPN6/ACTG1/CLIC1 14 GO:0032386 regulation of intracellular transport 18/376 337/18722 0.000171985795057237 0.00212243616511717 GZMB/RAC2/LCP1/FYN/MSN/ITGB2/TGFB1/FLNA/RAB29/SP100/TOMM7/PIK3R1/VAMP2/SORL1/CDC42/CD81/GCC2/PPP1R12A 18 GO:0002820 negative regulation of adaptive immune response 7/376 59/18722 0.00017312864709092 0.00212586217223118 KLRD1/IL7R/PTPRC/KLRC1/XCL1/HLA-F/PTPN6 7 GO:0031032 actomyosin structure organization 13/376 196/18722 0.000173360631335497 0.00212586217223118 GPR65/EVL/PTGER4/CNN2/WAS/EPB41/PFN1/PIK3R1/AKAP13/CDC42/ACTG1/CFLAR/ROCK1 13 GO:0032703 negative regulation of interleukin-2 production 5/376 27/18722 0.000178427140532562 0.0021670575459768 PTPRC/XCL1/TNFAIP3/ZFP36/LAPTM5 5 GO:0060333 interferon-gamma-mediated signaling pathway 5/376 27/18722 0.000178427140532562 0.0021670575459768 TXK/JAK1/IRF1/STAT1/SP100 5 GO:0010591 regulation of lamellipodium assembly 6/376 42/18722 0.000179516250905433 0.0021670575459768 RAC2/WAS/PIK3R1/ACTR3/CDC42/ACTR2 6 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 6/376 42/18722 0.000179516250905433 0.0021670575459768 ETS1/TNF/TGFB1/JUN/FOS/STAT3 6 GO:2000404 regulation of T cell migration 6/376 42/18722 0.000179516250905433 0.0021670575459768 CCL5/XCL2/XCL1/SPN/ITGA4/PYCARD 6 GO:0030833 regulation of actin filament polymerization 12/376 171/18722 0.00018146750976937 0.00218380931787673 TMSB4X/CORO1A/EVL/GMFG/WAS/TMSB10/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 12 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 4/376 15/18722 0.000183376510280658 0.00219316042388132 ZFP36/PABPC1/BTG2/TNRC6B 4 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 4/376 15/18722 0.000183376510280658 0.00219316042388132 ZFP36L2/ZFP36/PABPC1/TNRC6B 4 GO:0052548 regulation of endopeptidase activity 21/376 432/18722 0.000188074744015242 0.00224242964018173 CST7/MBP/PSMB9/FYN/LCK/TNF/PSMB8/IFI16/BST2/CDKN2D/CD44/CASP8/PSME1/LAPTM5/CARD16/SORL1/RPS6KA3/PYCARD/STAT3/CFLAR/ROCK1 21 GO:0060326 cell chemotaxis 17/376 310/18722 0.000190126625104698 0.0022599407125175 CCL4/CCL5/XCL2/TMSB4X/RAC2/XCL1/CORO1A/CXCR4/ITGB2/CCL3/GPSM3/FCER1G/CCL3L3/BIN2/DUSP1/CKLF/LYST 17 GO:0051495 positive regulation of cytoskeleton organization 14/376 226/18722 0.000201597398465127 0.00238895999710204 CORO1A/PLEK/GPR65/EVL/GMFG/WAS/FLNA/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/CDC42/ACTR2 14 GO:0043484 regulation of RNA splicing 11/376 148/18722 0.000203296799537356 0.00240175334819285 CELF2/DDX5/MBNL1/PIK3R1/SON/SRSF7/CLK1/NCL/SRSF5/SF1/DDX17 11 GO:0045619 regulation of lymphocyte differentiation 12/376 174/18722 0.000213389813715716 0.00250892648332825 IL7R/CD2/PTPRC/ZFP36L2/IKZF3/RUNX3/PRDM1/RASGRP1/IRF1/ID2/XBP1/PTPN6 12 GO:0002507 tolerance induction 5/376 28/18722 0.000213663416644728 0.00250892648332825 HLA-B/CD3E/HLA-E/TNFAIP3/CBLB 5 GO:0072659 protein localization to plasma membrane 16/376 284/18722 0.000215531193761396 0.00252321261578673 SKAP1/TNF/MYL12A/TGFB1/FLNA/ACTB/RAB8B/PIK3R1/PRKCH/CSK/VAMP2/SLC9A3R1/MACF1/CD81/VAMP5/ROCK1 16 GO:0071621 granulocyte chemotaxis 10/376 125/18722 0.00021673122815355 0.00252961900329821 CCL4/CCL5/XCL2/RAC2/XCL1/ITGB2/CCL3/FCER1G/CCL3L3/CKLF 10 GO:0070665 positive regulation of leukocyte proliferation 11/376 150/18722 0.000228595894482961 0.00266008736072515 CCL5/PTPRC/HLA-A/CD3E/HLA-E/XCL1/CORO1A/PTPN22/BST2/PYCARD/CD81 11 GO:0033631 cell-cell adhesion mediated by integrin 4/376 16/18722 0.000240642063648636 0.00278090994023078 CCL5/CD3E/SKAP1/ITGA4 4 GO:0034116 positive regulation of heterotypic cell-cell adhesion 4/376 16/18722 0.000240642063648636 0.00278090994023078 SKAP1/LCK/TNF/CD44 4 GO:0051090 regulation of DNA-binding transcription factor activity 21/376 440/18722 0.000241131803849688 0.00278090994023078 TMSB4X/XCL1/EOMES/TNF/TRIM22/MTDH/TNFAIP3/FLNA/ID2/SP100/CYLD/PRKCH/TERF2IP/CARD16/COMMD6/PIM1/PYCARD/STAT3/PRMT2/NFKBIA/CFLAR 21 GO:1903311 regulation of mRNA metabolic process 16/376 288/18722 0.000252289703972088 0.00290095727861081 ZFP36L2/CELF2/VIM/DDX5/MBNL1/ZFP36/PABPC1/SON/BTG2/SRSF7/NCL/CNOT6L/TNRC6B/SF1/DDX17/ROCK1 16 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 5/376 29/18722 0.00025395655892231 0.00290289576939219 ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B 5 GO:0010592 positive regulation of lamellipodium assembly 5/376 29/18722 0.00025395655892231 0.00290289576939219 RAC2/PIK3R1/ACTR3/CDC42/ACTR2 5 GO:0050878 regulation of body fluid levels 19/376 379/18722 0.000256922624856863 0.00292816226858925 PLEK/LCK/TXK/CYBA/MYL12A/PRKACB/FCER1G/WAS/FLNA/ACTB/RAB27A/DGKZ/TLN1/XBP1/PTPN6/MLLT6/ACTG1/CLIC1/APRT 19 GO:0035303 regulation of dephosphorylation 10/376 128/18722 0.00026287964618043 0.0029872687065958 PTPRC/PLEK/TNF/CALM1/TGFB1/SEMA4D/PPP1R15A/PPP1R2/PPP1R12A/ROCK1 10 GO:0030038 contractile actin filament bundle assembly 9/376 106/18722 0.000285838497469971 0.00322922500786045 GPR65/EVL/PTGER4/WAS/PFN1/PIK3R1/CDC42/ACTG1/ROCK1 9 GO:0043149 stress fiber assembly 9/376 106/18722 0.000285838497469971 0.00322922500786045 GPR65/EVL/PTGER4/WAS/PFN1/PIK3R1/CDC42/ACTG1/ROCK1 9 GO:0048247 lymphocyte chemotaxis 7/376 64/18722 0.000289338175380308 0.00325925996976365 CCL4/CCL5/XCL2/XCL1/CCL3/CCL3L3/CKLF 7 GO:0045577 regulation of B cell differentiation 5/376 30/18722 0.000299768954217845 0.00336697013795406 ZFP36L2/IKZF3/ID2/XBP1/PTPN6 5 GO:2000116 regulation of cysteine-type endopeptidase activity 14/376 235/18722 0.000300974217019787 0.00337073725708576 CST7/PSMB9/FYN/LCK/TNF/IFI16/CDKN2D/CD44/CASP8/LAPTM5/CARD16/RPS6KA3/PYCARD/CFLAR 14 GO:0033623 regulation of integrin activation 4/376 17/18722 0.000309721118855835 0.00345870125523446 PLEK/SKAP1/PTGER4/RAP1B 4 GO:0042326 negative regulation of phosphorylation 19/376 385/18722 0.000312723605570139 0.00348219532064451 PTPRC/PTPN22/CALM1/DDIT4/PIP4K2A/TGFB1/CDKN2D/TNFAIP3/SEMA4D/DUSP1/CSK/TERF2IP/CBLB/SORL1/PTPN6/PYCARD/STAT3/GADD45B/ROCK1 19 GO:0050853 B cell receptor signaling pathway 10/376 131/18722 0.000316983162012704 0.00351951218567114 TRDC/PTPRC/TRBC1/TRBC2/LCK/PTPN22/PRKCH/CMTM3/PTPN6/CD81 10 GO:0001774 microglial cell activation 6/376 47/18722 0.000337727517991661 0.0037284733111615 CST7/PTPRC/TNF/ITGB2/CCL3/TYROBP 6 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 6/376 47/18722 0.000337727517991661 0.0037284733111615 TNFAIP3/CASP8/LAPTM5/CYLD/CARD16/PYCARD 6 GO:2000377 regulation of reactive oxygen species metabolic process 11/376 157/18722 0.000339137546658675 0.00373340339006353 RAC2/FYN/CYBA/TNF/ITGB2/TYROBP/TGFB1/STK17A/RAB27A/STAT3/CFLAR 11 GO:0060055 angiogenesis involved in wound healing 5/376 31/18722 0.000351580232646883 0.00385941473514638 ETS1/TNF/CXCR4/TNFAIP3/XBP1 5 GO:0072665 protein localization to vacuole 7/376 67/18722 0.000384747640330032 0.00421157374655049 TNFAIP3/LAPTM5/SORL1/GNPTAB/VPS13C/CD81/GCC2 7 GO:0071800 podosome assembly 4/376 18/18722 0.000391934611905556 0.00426614219419672 LCP1/MSN/TNF/BIN2 4 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 4/376 18/18722 0.000391934611905556 0.00426614219419672 ZFP36L2/ZFP36/PABPC1/TNRC6B 4 GO:0072666 establishment of protein localization to vacuole 6/376 49/18722 0.000425257427017713 0.00461588943891775 TNFAIP3/LAPTM5/SORL1/GNPTAB/VPS13C/GCC2 6 GO:0052547 regulation of peptidase activity 21/376 461/18722 0.000447606702261306 0.00484490494766079 CST7/MBP/PSMB9/FYN/LCK/TNF/PSMB8/IFI16/BST2/CDKN2D/CD44/CASP8/PSME1/LAPTM5/CARD16/SORL1/RPS6KA3/PYCARD/STAT3/CFLAR/ROCK1 21 GO:0050671 positive regulation of lymphocyte proliferation 10/376 137/18722 0.000453315316249159 0.00488788221776064 CCL5/PTPRC/HLA-A/CD3E/HLA-E/XCL1/CORO1A/PTPN22/PYCARD/CD81 10 GO:0035304 regulation of protein dephosphorylation 8/376 90/18722 0.000454100025391957 0.00488788221776064 PTPRC/TNF/CALM1/TGFB1/PPP1R15A/PPP1R2/PPP1R12A/ROCK1 8 GO:0045058 T cell selection 6/376 50/18722 0.000475177972681108 0.00507248647150008 PTPRC/CD3D/CD3E/CD3G/SPN/STAT3 6 GO:0050901 leukocyte tethering or rolling 5/376 33/18722 0.000475199482494833 0.00507248647150008 SPN/TNF/ITGA4/SELPLG/ROCK1 5 GO:0071353 cellular response to interleukin-4 5/376 33/18722 0.000475199482494833 0.00507248647150008 IL2RG/XCL1/CORO1A/XBP1/RPL3 5 GO:0030041 actin filament polymerization 12/376 190/18722 0.000476486471129298 0.00507248647150008 TMSB4X/CORO1A/EVL/GMFG/WAS/TMSB10/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 12 GO:0032273 positive regulation of protein polymerization 10/376 138/18722 0.000480185783123217 0.00508393417924171 CORO1A/EVL/GMFG/WAS/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 10 GO:0032946 positive regulation of mononuclear cell proliferation 10/376 138/18722 0.000480185783123217 0.00508393417924171 CCL5/PTPRC/HLA-A/CD3E/HLA-E/XCL1/CORO1A/PTPN22/PYCARD/CD81 10 GO:0007163 establishment or maintenance of cell polarity 13/376 218/18722 0.000485743801620213 0.00512876629776111 CCL4/RAC2/CD3G/SPN/MSN/CYTH1/ACTB/RAP1B/SLC9A3R1/ACTR3/CDC42/ACTR2/ROCK1 13 GO:0002548 monocyte chemotaxis 7/376 70/18722 0.000503801222630181 0.00530497211329335 CCL4/CCL5/XCL2/XCL1/CCL3/CCL3L3/DUSP1 7 GO:0097191 extrinsic apoptotic signaling pathway 13/376 219/18722 0.000507231207833452 0.00532409098222231 PTPRC/FYN/TNF/STK4/TGFB1/TNFAIP3/CASP8/SP100/CYLD/PIK3R1/PYCARD/CFLAR/MCL1 13 GO:0045598 regulation of fat cell differentiation 10/376 139/18722 0.000508364816367033 0.00532409098222231 ZFP36L2/RORA/TNF/STK4/TGFB1/ZFP36/ID2/CCDC85B/XBP1/PIM1 10 GO:0002440 production of molecular mediator of immune response 16/376 308/18722 0.000529086803801218 0.00552617618525531 PTPRC/HLA-A/B2M/HLA-E/XCL1/CD96/HLA-F/SPON2/PTPN22/TNF/BST2/TGFB1/LAPTM5/XBP1/SAMHD1/CD81 16 GO:0006417 regulation of translation 21/376 468/18722 0.000544477538499443 0.00567164102603587 CCL5/GZMB/ZFP36L2/TNF/VIM/RPL10/ZFP36/EIF1/RPS4X/PABPC1/BTG2/RPS6KA3/EIF4A2/PPP1R15A/STAT3/NCL/CNOT6L/DDX6/TNRC6B/ROCK1/DNAJC1 21 GO:0010922 positive regulation of phosphatase activity 5/376 34/18722 0.000548045784656429 0.00569252898786679 PTPRC/PLEK/CALM1/PPP1R15A/PPP1R12A 5 GO:0043550 regulation of lipid kinase activity 7/376 71/18722 0.00054942086231282 0.00569252898786679 PIP4K2A/TGFB1/RBL2/DGKZ/PIK3R1/CDC42/CD81 7 GO:0032755 positive regulation of interleukin-6 production 8/376 93/18722 0.000566378394802573 0.00585257674629325 MBP/SPON2/CYBA/TNF/TYROBP/XBP1/PYCARD/STAT3 8 GO:0050921 positive regulation of chemotaxis 10/376 141/18722 0.000568845243467375 0.00586243435754276 CCL4/CCL5/XCL2/TMSB4X/RAC2/XCL1/CXCR4/CCL3/GPSM3/TGFB1 10 GO:0002218 activation of innate immune response 6/376 52/18722 0.000588629333252102 0.00603422927606321 KLRD1/PYHIN1/FYN/IFI16/TYROBP/PYCARD 6 GO:0043392 negative regulation of DNA binding 6/376 52/18722 0.000588629333252102 0.00603422927606321 GZMA/TMSB4X/IFI16/JUN/SP100/NFKBIA 6 GO:0006470 protein dephosphorylation 15/376 281/18722 0.000592618507926193 0.0060590942433087 PTPRC/LCK/PTPN22/TNF/PTPN4/CALM1/TGFB1/PPP2R5C/DUSP1/PTPN6/PTP4A2/PPP1R15A/PPP1R2/PPP1R12A/ROCK1 15 GO:0032495 response to muramyl dipeptide 4/376 20/18722 0.000601168985848372 0.00610539663363448 PTPN22/VIM/TNFAIP3/NFKBIA 4 GO:0032930 positive regulation of superoxide anion generation 4/376 20/18722 0.000601168985848372 0.00610539663363448 CYBA/ITGB2/TYROBP/TGFB1 4 GO:0016482 cytosolic transport 11/376 168/18722 0.000601873939109257 0.00610539663363448 CORO1A/TBC1D10C/MSN/PIP4K2A/FLNA/RAB29/LAPTM5/SORL1/VPS13C/ACTR2/GCC2 11 GO:0018108 peptidyl-tyrosine phosphorylation 18/376 375/18722 0.000618994469291046 0.00626267250261828 CCL5/PTPRC/CD3E/FYN/LCK/MATK/TXK/JAK1/TNF/ITGB2/TGFB1/CD44/SEMA4D/CSK/CBLB/PTPN6/CLK1/CD81 18 GO:0039694 viral RNA genome replication 5/376 35/18722 0.000628965937281276 0.0063157933123415 APOBEC3G/APOBEC3C/RAB29/CDC42/MPHOSPH8 5 GO:0097305 response to alcohol 14/376 253/18722 0.000629722161062122 0.0063157933123415 KLF2/FYN/GNG2/CYBA/CALM1/PTGER4/CCL3/TGFB1/CASP8/FOS/EEF1B2/STAT3/FOSB/ACTR2 14 GO:0022612 gland morphogenesis 9/376 118/18722 0.00063076439016159 0.0063157933123415 CRIP1/MSN/TNF/TGFB1/TNFAIP3/XBP1/SLC9A3R1/CDC42/CFLAR 9 GO:0051101 regulation of DNA binding 9/376 118/18722 0.00063076439016159 0.0063157933123415 GZMA/TMSB4X/PYHIN1/CALM1/IFI16/TGFB1/JUN/SP100/NFKBIA 9 GO:0050848 regulation of calcium-mediated signaling 7/376 73/18722 0.000650496643290562 0.00649658374420342 CCL4/CD3E/PLEK/TBC1D10C/TNF/CALM1/CCL3 7 GO:0018212 peptidyl-tyrosine modification 18/376 378/18722 0.000678881850101367 0.00676264053764216 CCL5/PTPRC/CD3E/FYN/LCK/MATK/TXK/JAK1/TNF/ITGB2/TGFB1/CD44/SEMA4D/CSK/CBLB/PTPN6/CLK1/CD81 18 GO:0042119 neutrophil activation 5/376 36/18722 0.000718513566634932 0.00712081859516716 CCL5/ITGB2/TYROBP/FCER1G/KMT2E 5 GO:0070670 response to interleukin-4 5/376 36/18722 0.000718513566634932 0.00712081859516716 IL2RG/XCL1/CORO1A/XBP1/RPL3 5 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 6/376 54/18722 0.000722047870381095 0.00713759055542536 ETS1/TNF/TGFB1/JUN/FOS/STAT3 6 GO:0032516 positive regulation of phosphoprotein phosphatase activity 4/376 21/18722 0.00073093581414945 0.00715246535310384 PTPRC/CALM1/PPP1R15A/PPP1R12A 4 GO:0033630 positive regulation of cell adhesion mediated by integrin 4/376 21/18722 0.00073093581414945 0.00715246535310384 CCL5/CD3E/SKAP1/PTPN6 4 GO:0035455 response to interferon-alpha 4/376 21/18722 0.00073093581414945 0.00715246535310384 IFITM1/IFITM2/PYHIN1/BST2 4 GO:0150105 protein localization to cell-cell junction 4/376 21/18722 0.00073093581414945 0.00715246535310384 JAK1/FLNA/ACTB/ACTG1 4 GO:1990868 response to chemokine 8/376 97/18722 0.000749944493869697 0.00730159526066602 CCL4/CCL5/XCL2/XCL1/CXCR4/CCL3/CCL3L3/DUSP1 8 GO:1990869 cellular response to chemokine 8/376 97/18722 0.000749944493869697 0.00730159526066602 CCL4/CCL5/XCL2/XCL1/CXCR4/CCL3/CCL3L3/DUSP1 8 GO:0045444 fat cell differentiation 13/376 229/18722 0.000770151029170265 0.00747953693743051 ZFP36L2/RORA/TNF/PLAC8/PSMB8/STK4/TGFB1/NR4A2/ZFP36/ID2/CCDC85B/XBP1/PIM1 13 GO:0002369 T cell cytokine production 5/376 37/18722 0.000817254492224343 0.00785821627138791 HLA-A/B2M/XCL1/HLA-F/CD81 5 GO:0002724 regulation of T cell cytokine production 5/376 37/18722 0.000817254492224343 0.00785821627138791 HLA-A/B2M/XCL1/HLA-F/CD81 5 GO:0006623 protein targeting to vacuole 5/376 37/18722 0.000817254492224343 0.00785821627138791 LAPTM5/SORL1/GNPTAB/VPS13C/GCC2 5 GO:1902745 positive regulation of lamellipodium organization 5/376 37/18722 0.000817254492224343 0.00785821627138791 RAC2/PIK3R1/ACTR3/CDC42/ACTR2 5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 3/376 10/18722 0.000868248374062495 0.00828685332387233 ITGAL/APBB1IP/CD81 3 GO:0050861 positive regulation of B cell receptor signaling pathway 3/376 10/18722 0.000868248374062495 0.00828685332387233 PRKCH/CMTM3/CD81 3 GO:0071803 positive regulation of podosome assembly 3/376 10/18722 0.000868248374062495 0.00828685332387233 LCP1/MSN/TNF 3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 6/376 56/18722 0.000877718789882448 0.0083106360159237 ZFP36L2/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B 6 GO:0032816 positive regulation of natural killer cell activation 4/376 22/18722 0.000879318907491282 0.0083106360159237 HLA-E/HLA-F/RASGRP1/TYROBP 4 GO:0045061 thymic T cell selection 4/376 22/18722 0.000879318907491282 0.0083106360159237 PTPRC/CD3D/CD3E/CD3G 4 GO:0061042 vascular wound healing 4/376 22/18722 0.000879318907491282 0.0083106360159237 TNF/CXCR4/TNFAIP3/XBP1 4 GO:0044728 DNA methylation or demethylation 8/376 100/18722 0.000916805511674596 0.0086438475857398 APOBEC3G/APOBEC3C/FOS/KMT2A/KMT2E/MPHOSPH8/ATRX/ATF7IP 8 GO:2001233 regulation of apoptotic signaling pathway 17/376 356/18722 0.000920587323997601 0.00865843660313277 PTPRC/FYN/LCK/TNF/STK4/CDKN2D/CD44/TNFAIP3/NR4A2/SP100/CYLD/XBP1/SLC9A3R1/IVNS1ABP/PYCARD/CFLAR/MCL1 17 GO:0072594 establishment of protein localization to organelle 19/376 422/18722 0.000950059040740265 0.00891399221033542 GZMB/RAC2/TXNIP/CALM1/TGFB1/TNFAIP3/FLNA/IL10RA/RAB8B/LAPTM5/TOMM7/PIK3R1/CBLB/SORL1/GNPTAB/VPS13C/STAT3/GCC2/NFKBIA 19 GO:2001236 regulation of extrinsic apoptotic signaling pathway 10/376 151/18722 0.000967568499192587 0.00905634766756346 PTPRC/FYN/TNF/STK4/TNFAIP3/SP100/CYLD/PYCARD/CFLAR/MCL1 10 GO:0048024 regulation of mRNA splicing, via spliceosome 8/376 101/18722 0.000978600932613898 0.00911557359105494 CELF2/DDX5/MBNL1/SON/SRSF7/NCL/SF1/DDX17 8 GO:0050830 defense response to Gram-positive bacterium 8/376 101/18722 0.000978600932613898 0.00911557359105494 IL7R/HLA-A/HLA-E/TNF/GBP4/GBP2/RPL39/PYCARD 8 GO:0016064 immunoglobulin mediated immune response 12/376 207/18722 0.00101390760262229 0.00941971792248862 TRDC/PTPRC/B2M/TRBC1/HLA-E/XCL1/TRBC2/TNF/TGFB1/FCER1G/PTPN6/CD81 12 GO:0010950 positive regulation of endopeptidase activity 11/376 179/18722 0.0010161140881549 0.00941971792248862 MBP/FYN/LCK/TNF/IFI16/CASP8/PSME1/LAPTM5/PYCARD/STAT3/CFLAR 11 GO:0034314 Arp2/3 complex-mediated actin nucleation 5/376 39/18722 0.00104463503908018 0.00962058780268939 GMFG/WAS/ACTR3/ARPC5L/ACTR2 5 GO:0006622 protein targeting to lysosome 4/376 23/18722 0.00104771304586708 0.00962058780268939 LAPTM5/SORL1/GNPTAB/GCC2 4 GO:0072677 eosinophil migration 4/376 23/18722 0.00104771304586708 0.00962058780268939 CCL4/CCL5/PTGER4/CCL3 4 GO:2000737 negative regulation of stem cell differentiation 4/376 23/18722 0.00104771304586708 0.00962058780268939 ZFP36L2/LBH/N4BP2L2/STAT3 4 GO:0043525 positive regulation of neuron apoptotic process 6/376 58/18722 0.00105803685966077 0.00969241804062765 TNF/CCL3/TYROBP/JUN/CDC42/MCL1 6 GO:0043409 negative regulation of MAPK cascade 11/376 180/18722 0.00106326066491374 0.0097172997088225 PTPRC/DUSP2/PTPN22/TBC1D10C/CYLD/DUSP1/CSK/SLC9A3R1/SORL1/PTPN6/TAOK3 11 GO:0051348 negative regulation of transferase activity 14/376 268/18722 0.00110020321602194 0.0100312646166706 PTPRC/PTPN22/PIP4K2A/CDKN2D/TNFAIP3/ZFP36/DUSP1/CSK/CBLB/SORL1/EIF4A2/PTPN6/PYCARD/GADD45B 14 GO:0031589 cell-substrate adhesion 17/376 363/18722 0.00113800539053032 0.010351574855176 RAC2/CD3E/CORO1A/CD96/SKAP1/ITGAL/ITGB2/ITGA4/STK4/CD44/FLNA/LGALS1/PIK3R1/CDC42/MACF1/ACTG1/ROCK1 17 GO:0019724 B cell mediated immunity 12/376 210/18722 0.00114777466661288 0.01041598789959 TRDC/PTPRC/B2M/TRBC1/HLA-E/XCL1/TRBC2/TNF/TGFB1/FCER1G/PTPN6/CD81 12 GO:0035306 positive regulation of dephosphorylation 6/376 59/18722 0.00115821514787623 0.0104861768645336 PTPRC/PLEK/CALM1/TGFB1/PPP1R15A/PPP1R12A 6 GO:0002714 positive regulation of B cell mediated immunity 5/376 40/18722 0.00117445908232938 0.0105253435159462 PTPRC/HLA-E/XCL1/TNF/TGFB1 5 GO:0002891 positive regulation of immunoglobulin mediated immune response 5/376 40/18722 0.00117445908232938 0.0105253435159462 PTPRC/HLA-E/XCL1/TNF/TGFB1 5 GO:0033625 positive regulation of integrin activation 3/376 11/18722 0.00117612225610443 0.0105253435159462 PLEK/SKAP1/RAP1B 3 GO:0033632 regulation of cell-cell adhesion mediated by integrin 3/376 11/18722 0.00117612225610443 0.0105253435159462 CCL5/CD3E/SKAP1 3 GO:1905668 positive regulation of protein localization to endosome 3/376 11/18722 0.00117612225610443 0.0105253435159462 MSN/ABHD17A/SORL1 3 GO:0002726 positive regulation of T cell cytokine production 4/376 24/18722 0.00123751374537588 0.0109985453287421 HLA-A/B2M/XCL1/CD81 4 GO:0032928 regulation of superoxide anion generation 4/376 24/18722 0.00123751374537588 0.0109985453287421 CYBA/ITGB2/TYROBP/TGFB1 4 GO:0050855 regulation of B cell receptor signaling pathway 4/376 24/18722 0.00123751374537588 0.0109985453287421 PTPN22/PRKCH/CMTM3/CD81 4 GO:0002712 regulation of B cell mediated immunity 6/376 60/18722 0.00126549924153073 0.0111959122395698 PTPRC/HLA-E/XCL1/TNF/TGFB1/PTPN6 6 GO:0002889 regulation of immunoglobulin mediated immune response 6/376 60/18722 0.00126549924153073 0.0111959122395698 PTPRC/HLA-E/XCL1/TNF/TGFB1/PTPN6 6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 7/376 82/18722 0.00130156721928568 0.0114887767078178 TNF/STK4/TNFAIP3/CASP8/SP100/PIK3R1/CFLAR 7 GO:0050691 regulation of defense response to virus by host 5/376 41/18722 0.001315843424711 0.0115883937971708 APOBEC3G/PTPN22/TNFAIP3/STAT1/PYCARD 5 GO:0042116 macrophage activation 8/376 106/18722 0.00133946004919683 0.0117696319515595 CST7/PTPRC/RORA/TNF/ITGB2/CCL3/TYROBP/JUND 8 GO:0120032 regulation of plasma membrane bounded cell projection assembly 11/376 186/18722 0.00138557639052296 0.0121473043286798 RAC2/EVL/WAS/PFN1/CYLD/PIK3R1/ACTR3/ODF2L/CDC42EP3/CDC42/ACTR2 11 GO:0060706 cell differentiation involved in embryonic placenta development 4/376 25/18722 0.00145011326674247 0.0125990782704642 EOMES/PRDM1/STK4/CASP8 4 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 4/376 25/18722 0.00145011326674247 0.0125990782704642 PTPN22/TNFAIP3/CYLD/NFKBIA 4 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 4/376 25/18722 0.00145011326674247 0.0125990782704642 TNF/DDX5/TGFB1/STAT3 4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 4/376 25/18722 0.00145011326674247 0.0125990782704642 ETS1/TNF/ITGB2/ITGA4 4 GO:0048545 response to steroid hormone 16/376 339/18722 0.00145506751333866 0.0126138403001953 TXNIP/ZFP36L2/CYBA/TNF/CALM1/DDIT4/DDX5/TGFB1/LBH/ZFP36/FOS/DUSP1/FOSB/PRMT2/CFLAR/DDX17 16 GO:0045445 myoblast differentiation 7/376 84/18722 0.00149869100408326 0.0129112054884916 TNF/BTG1/DDX5/TGFB1/MBNL1/LGALS1/DDX17 7 GO:0061157 mRNA destabilization 7/376 84/18722 0.00149869100408326 0.0129112054884916 ZFP36L2/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 7 GO:0032623 interleukin-2 production 6/376 62/18722 0.00150269772266057 0.0129112054884916 PTPRC/CD3E/XCL1/TNFAIP3/ZFP36/LAPTM5 6 GO:0032663 regulation of interleukin-2 production 6/376 62/18722 0.00150269772266057 0.0129112054884916 PTPRC/CD3E/XCL1/TNFAIP3/ZFP36/LAPTM5 6 GO:0060491 regulation of cell projection assembly 11/376 188/18722 0.00150933297184107 0.0129395249245225 RAC2/EVL/WAS/PFN1/CYLD/PIK3R1/ACTR3/ODF2L/CDC42EP3/CDC42/ACTR2 11 GO:0002664 regulation of T cell tolerance induction 3/376 12/18722 0.00154491128536077 0.0131572114962043 HLA-B/CD3E/CBLB 3 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 3/376 12/18722 0.00154491128536077 0.0131572114962043 HLA-E/TNF/CD81 3 GO:1905666 regulation of protein localization to endosome 3/376 12/18722 0.00154491128536077 0.0131572114962043 MSN/ABHD17A/SORL1 3 GO:0032233 positive regulation of actin filament bundle assembly 6/376 63/18722 0.00163328177745898 0.0138793133501174 PLEK/GPR65/EVL/FLNA/PFN1/CDC42 6 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 4/376 26/18722 0.00168689689203497 0.0142412319316678 PTPN22/TNFAIP3/CYLD/NFKBIA 4 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 4/376 26/18722 0.00168689689203497 0.0142412319316678 TNF/DDX5/TGFB1/STAT3 4 GO:1900017 positive regulation of cytokine production involved in inflammatory response 4/376 26/18722 0.00168689689203497 0.0142412319316678 GBP5/TNF/GPSM3/STAT3 4 GO:2000117 negative regulation of cysteine-type endopeptidase activity 7/376 86/18722 0.00171834215129319 0.0144751648614372 CST7/TNF/IFI16/CDKN2D/CD44/CARD16/RPS6KA3 7 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 8/376 111/18722 0.00179892444138911 0.0151211110854291 CCL5/HCST/FYN/RASGRP1/TNF/SEMA4D/SLC9A3R1/PTPN6 8 GO:0061014 positive regulation of mRNA catabolic process 7/376 87/18722 0.00183714482903259 0.0154089528409119 ZFP36L2/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 7 GO:0000956 nuclear-transcribed mRNA catabolic process 8/376 112/18722 0.00190418444411025 0.0158682037009188 ZFP36L2/DDX5/ATM/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B 8 GO:0046632 alpha-beta T cell differentiation 8/376 112/18722 0.00190418444411025 0.0158682037009188 RUNX3/RORA/EOMES/PRDM1/SPN/IRF1/PTGER4/STAT3 8 GO:1901222 regulation of NIK/NF-kappaB signaling 8/376 112/18722 0.00190418444411025 0.0158682037009188 TMSB4X/PTPN22/TNF/LITAF/LAPTM5/CYLD/TERF2IP/NFKBIA 8 GO:0050920 regulation of chemotaxis 12/376 223/18722 0.00190890225815896 0.0158733825115149 CCL4/CCL5/XCL2/TMSB4X/RAC2/XCL1/CXCR4/CCL3/GPSM3/TGFB1/SEMA4D/DUSP1 12 GO:0050779 RNA destabilization 7/376 88/18722 0.00196222098329439 0.0162470220304824 ZFP36L2/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 7 GO:0070098 chemokine-mediated signaling pathway 7/376 88/18722 0.00196222098329439 0.0162470220304824 CCL4/CCL5/XCL2/XCL1/CXCR4/CCL3/CCL3L3 7 GO:0034112 positive regulation of homotypic cell-cell adhesion 3/376 13/18722 0.00197863556731523 0.0163132187730777 CCL5/JAK1/LGALS1 3 GO:0071801 regulation of podosome assembly 3/376 13/18722 0.00197863556731523 0.0163132187730777 LCP1/MSN/TNF 3 GO:0035307 positive regulation of protein dephosphorylation 5/376 45/18722 0.00200934036684607 0.0165311972856232 PTPRC/CALM1/TGFB1/PPP1R15A/PPP1R12A 5 GO:0031960 response to corticosteroid 10/376 167/18722 0.00206016046138809 0.0169133936183874 ZFP36L2/CYBA/TNF/CALM1/DDIT4/ZFP36/FOS/DUSP1/FOSB/CFLAR 10 GO:0032715 negative regulation of interleukin-6 production 6/376 66/18722 0.00207709307724458 0.0170163544911686 KLF2/PTPN22/TNF/TNFAIP3/CSK/PTPN6 6 GO:0022408 negative regulation of cell-cell adhesion 11/376 196/18722 0.00209827497724368 0.0171175063933037 XCL1/MBP/RUNX3/PTPN22/SPN/IRF1/TGFB1/FXYD5/LAPTM5/CBLB/PTPN6 11 GO:0043393 regulation of protein binding 11/376 196/18722 0.00209827497724368 0.0171175063933037 B2M/HOPX/ITGA4/STK4/EPB41/ACTB/CBLB/CARD16/SORL1/CDC42/ROCK1 11 GO:0010952 positive regulation of peptidase activity 11/376 197/18722 0.00218347411754128 0.0177751306837657 MBP/FYN/LCK/TNF/IFI16/CASP8/PSME1/LAPTM5/PYCARD/STAT3/CFLAR 11 GO:0046777 protein autophosphorylation 12/376 227/18722 0.00221279196934721 0.0179760353903992 PTPRC/FYN/TXK/CALM1/STK4/STK17B/ATM/STK10/CSK/PIM1/TAOK3/CLK1 12 GO:0061462 protein localization to lysosome 5/376 46/18722 0.00221784261466017 0.0179793726606865 LAPTM5/SORL1/GNPTAB/CD81/GCC2 5 GO:0070664 negative regulation of leukocyte proliferation 7/376 90/18722 0.00223207818891374 0.0180193812125849 XCL1/SPN/TYROBP/ATM/TNFAIP3/CBLB/PTPN6 7 GO:0097581 lamellipodium organization 7/376 90/18722 0.00223207818891374 0.0180193812125849 RAC2/CD44/WAS/PIK3R1/ACTR3/CDC42/ACTR2 7 GO:0010818 T cell chemotaxis 4/376 28/18722 0.00223850213099181 0.0180336710137074 CCL5/XCL2/XCL1/CCL3 4 GO:0051209 release of sequestered calcium ion into cytosol 8/376 115/18722 0.00224935188945245 0.0180834825137515 PTPRC/XCL1/CORO1A/LCK/CYBA/CALM1/CCL3/PTPN6 8 GO:0034504 protein localization to nucleus 14/376 290/18722 0.00229903588631688 0.0184446460858756 PYHIN1/TXNIP/FYN/SYNE1/RASSF5/TGFB1/FLNA/GBP2/SP100/SUN2/PIK3R1/CBLB/STAT3/NFKBIA 14 GO:0050729 positive regulation of inflammatory response 9/376 142/18722 0.00231819583492857 0.0185216677532953 ETS1/HLA-E/ALOX5AP/TNF/PTGER4/CCL3/GPSM3/CD81/NFKBIA 9 GO:0097553 calcium ion transmembrane import into cytosol 9/376 142/18722 0.00231819583492857 0.0185216677532953 PTPRC/XCL1/CORO1A/FYN/LCK/CYBA/CALM1/CCL3/PTPN6 9 GO:0051283 negative regulation of sequestering of calcium ion 8/376 116/18722 0.0023747125654248 0.0189341794053932 PTPRC/XCL1/CORO1A/LCK/CYBA/CALM1/CCL3/PTPN6 8 GO:0038061 NIK/NF-kappaB signaling 9/376 143/18722 0.00243123543303749 0.0193450457967562 TMSB4X/PTPN22/TNF/LITAF/LAPTM5/CYLD/TERF2IP/REL/NFKBIA 9 GO:0045216 cell-cell junction organization 11/376 200/18722 0.00245606457414174 0.0194219655796391 TNF/TGFB1/MTDH/FLNA/ACTB/TLN1/PRKCH/CSK/CDC42/ACTG1/ROCK1 11 GO:0045055 regulated exocytosis 12/376 230/18722 0.00246575684075913 0.0194219655796391 RAC2/CORO1A/PLEK/HLA-F/RASGRP1/LAT/CALM1/ITGB2/CCL3/RAB27A/VAMP2/RAP1B 12 GO:0001771 immunological synapse formation 3/376 14/18722 0.00248099947404422 0.0194219655796391 PRF1/MSN/CD81 3 GO:0002475 antigen processing and presentation via MHC class Ib 3/376 14/18722 0.00248099947404422 0.0194219655796391 B2M/HLA-E/HLA-F 3 GO:0002517 T cell tolerance induction 3/376 14/18722 0.00248099947404422 0.0194219655796391 HLA-B/CD3E/CBLB 3 GO:0043374 CD8-positive, alpha-beta T cell differentiation 3/376 14/18722 0.00248099947404422 0.0194219655796391 RUNX3/EOMES/IRF1 3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 3/376 14/18722 0.00248099947404422 0.0194219655796391 PYHIN1/DDX5/ATM 3 GO:0051645 Golgi localization 3/376 14/18722 0.00248099947404422 0.0194219655796391 YWHAZ/SLC9A3R1/CDC42 3 GO:0014065 phosphatidylinositol 3-kinase signaling 9/376 144/18722 0.0025486084264365 0.0199110033315351 CCL5/HCST/FYN/RASGRP1/TNF/SEMA4D/PIK3R1/SLC9A3R1/PTPN6 9 GO:0034067 protein localization to Golgi apparatus 4/376 29/18722 0.00255602942252292 0.0199288008295298 GBP5/SORL1/VPS13C/GCC2 4 GO:0051282 regulation of sequestering of calcium ion 8/376 118/18722 0.00264182857623141 0.0205152018695325 PTPRC/XCL1/CORO1A/LCK/CYBA/CALM1/CCL3/PTPN6 8 GO:1903313 positive regulation of mRNA metabolic process 8/376 118/18722 0.00264182857623141 0.0205152018695325 ZFP36L2/ZFP36/PABPC1/BTG2/NCL/CNOT6L/TNRC6B/ROCK1 8 GO:0032271 regulation of protein polymerization 12/376 232/18722 0.00264713856253087 0.0205153238596143 TMSB4X/CORO1A/EVL/GMFG/WAS/TMSB10/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 12 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 5/376 48/18722 0.00268144970181795 0.0207397556777336 PTPRC/TNF/STK4/CYLD/PYCARD 5 GO:0032088 negative regulation of NF-kappaB transcription factor activity 7/376 93/18722 0.00268951748195772 0.0207607176147135 TMSB4X/TNFAIP3/CYLD/COMMD6/PYCARD/PRMT2/NFKBIA 7 GO:0032869 cellular response to insulin stimulus 11/376 203/18722 0.00275556925485471 0.0212282919732843 PIP4K2A/STAT1/RAB8B/UCP2/PIK3R1/VAMP2/XBP1/SORL1/SRSF5/CFLAR/APRT 11 GO:0030522 intracellular receptor signaling pathway 13/376 265/18722 0.00283545156144762 0.0218003468266062 KLF2/RORA/PTPN22/DDX5/LBH/TNFAIP3/NR4A2/CYLD/PIM1/STAT3/PRMT2/NFKBIA/DDX17 13 GO:0002690 positive regulation of leukocyte chemotaxis 7/376 94/18722 0.00285696104765043 0.0218789013036471 CCL4/CCL5/XCL2/RAC2/XCL1/CCL3/GPSM3 7 GO:0030316 osteoclast differentiation 7/376 94/18722 0.00285696104765043 0.0218789013036471 TNF/CCL3/TYROBP/JUNB/FOS/PIK3R1/CD81 7 GO:1905475 regulation of protein localization to membrane 10/376 175/18722 0.00289577440173227 0.0221323980408532 GZMB/FYN/TNF/ITGB2/TGFB1/ACTB/PIK3R1/PRKCH/CSK/CD81 10 GO:0070168 negative regulation of biomineral tissue development 4/376 30/18722 0.00290314641764678 0.022145063717286 SRGN/CCL3/TGFB1/ROCK1 4 GO:0006304 DNA modification 8/376 120/18722 0.00293187113201452 0.0222781044068766 APOBEC3G/APOBEC3C/FOS/KMT2A/KMT2E/MPHOSPH8/ATRX/ATF7IP 8 GO:0009409 response to cold 5/376 49/18722 0.0029378351875907 0.0222781044068766 PLAC8/CASP8/FOS/UCP2/NFKBIA 5 GO:1904894 positive regulation of receptor signaling pathway via STAT 5/376 49/18722 0.0029378351875907 0.0222781044068766 CCL5/IL7R/TNF/TGFB1/IL10RA 5 GO:0061515 myeloid cell development 6/376 71/18722 0.0030115953296782 0.0227928357470762 KLF2/PIP4K2A/TYROBP/EVI2B/LYAR/PTPN6 6 GO:0032479 regulation of type I interferon production 7/376 95/18722 0.0030322781986416 0.0228125148517675 PTPN22/IRF1/STAT1/CYLD/ISG15/REL/PYCARD 7 GO:0032606 type I interferon production 7/376 95/18722 0.0030322781986416 0.0228125148517675 PTPN22/IRF1/STAT1/CYLD/ISG15/REL/PYCARD 7 GO:0010820 positive regulation of T cell chemotaxis 3/376 15/18722 0.00305540521498512 0.0228125148517675 CCL5/XCL2/XCL1 3 GO:0098760 response to interleukin-7 3/376 15/18722 0.00305540521498512 0.0228125148517675 IL7R/IL2RG/LSP1 3 GO:0098761 cellular response to interleukin-7 3/376 15/18722 0.00305540521498512 0.0228125148517675 IL7R/IL2RG/LSP1 3 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA 3/376 15/18722 0.00305540521498512 0.0228125148517675 TNF/TGFB1/STAT3 3 GO:2000345 regulation of hepatocyte proliferation 3/376 15/18722 0.00305540521498512 0.0228125148517675 TNFAIP3/XBP1/CFLAR 3 GO:0051384 response to glucocorticoid 9/376 148/18722 0.00306377216766849 0.0228309945186834 ZFP36L2/TNF/CALM1/DDIT4/ZFP36/FOS/DUSP1/FOSB/CFLAR 9 GO:0008380 RNA splicing 18/376 434/18722 0.003124411205584 0.0232381831509366 CELF2/DDX5/MBNL1/PIK3R1/PABPC1/SON/SRSF7/PNN/IVNS1ABP/CLK1/NCL/C9orf78/SRSF5/PRPF38B/ZRANB2/SCAF11/SF1/DDX17 18 GO:0043405 regulation of MAP kinase activity 10/376 177/18722 0.00314205520463207 0.0233246435209756 PTPN22/RASGRP1/TNF/TGFB1/DUSP1/CSK/SORL1/AKAP13/PTPN6/TAOK3 10 GO:0033673 negative regulation of kinase activity 12/376 237/18722 0.00314846622183708 0.0233275460986973 PTPRC/PTPN22/PIP4K2A/CDKN2D/TNFAIP3/DUSP1/CSK/CBLB/SORL1/PTPN6/PYCARD/GADD45B 12 GO:0002639 positive regulation of immunoglobulin production 5/376 50/18722 0.00321146376702509 0.0236889170483771 PTPRC/HLA-E/XCL1/TGFB1/XBP1 5 GO:0019083 viral transcription 5/376 50/18722 0.00321146376702509 0.0236889170483771 CCL4/CCL5/CCL3/JUN/ZFP36 5 GO:0030032 lamellipodium assembly 6/376 72/18722 0.00323098893488536 0.0236889170483771 RAC2/WAS/PIK3R1/ACTR3/CDC42/ACTR2 6 GO:0030330 DNA damage response, signal transduction by p53 class mediator 6/376 72/18722 0.00323098893488536 0.0236889170483771 PYHIN1/DDX5/ATM/CD44/SP100/ATRX 6 GO:0033627 cell adhesion mediated by integrin 6/376 72/18722 0.00323098893488536 0.0236889170483771 CCL5/CD3E/SKAP1/ITGB2/ITGA4/PTPN6 6 GO:0002688 regulation of leukocyte chemotaxis 8/376 122/18722 0.00324614579424213 0.0236889170483771 CCL4/CCL5/XCL2/RAC2/XCL1/CCL3/GPSM3/DUSP1 8 GO:0050868 negative regulation of T cell activation 8/376 122/18722 0.00324614579424213 0.0236889170483771 XCL1/RUNX3/PTPN22/SPN/IRF1/LAPTM5/CBLB/PTPN6 8 GO:0051208 sequestering of calcium ion 8/376 122/18722 0.00324614579424213 0.0236889170483771 PTPRC/XCL1/CORO1A/LCK/CYBA/CALM1/CCL3/PTPN6 8 GO:0002230 positive regulation of defense response to virus by host 4/376 31/18722 0.00328115622283196 0.0238098883211121 APOBEC3G/PTPN22/STAT1/PYCARD 4 GO:0090162 establishment of epithelial cell polarity 4/376 31/18722 0.00328115622283196 0.0238098883211121 MSN/CYTH1/SLC9A3R1/CDC42 4 GO:0110150 negative regulation of biomineralization 4/376 31/18722 0.00328115622283196 0.0238098883211121 SRGN/CCL3/TGFB1/ROCK1 4 GO:0072593 reactive oxygen species metabolic process 12/376 239/18722 0.00336937108920597 0.0244043233096694 RAC2/FYN/CYBA/TNF/DDIT4/ITGB2/TYROBP/TGFB1/STK17A/RAB27A/STAT3/CFLAR 12 GO:0051222 positive regulation of protein transport 14/376 303/18722 0.00341388034332681 0.0246805715119243 GZMB/RAC2/FYN/TNF/ITGB2/TGFB1/FLNA/RAB29/TOMM7/PIK3R1/VAMP2/SORL1/CDC42/CD81 14 GO:0002637 regulation of immunoglobulin production 6/376 73/18722 0.00346207779681921 0.0249824049584254 PTPRC/HLA-E/XCL1/TNF/TGFB1/XBP1 6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 5/376 51/18722 0.0035029765548444 0.0252305467472529 RORA/TNFAIP3/CASP8/STAT1/PYCARD 5 GO:0051092 positive regulation of NF-kappaB transcription factor activity 9/376 152/18722 0.00365778185039095 0.0260085924385677 TNF/TRIM22/MTDH/PRKCH/TERF2IP/CARD16/PYCARD/STAT3/CFLAR 9 GO:0010959 regulation of metal ion transport 17/376 406/18722 0.00365834044183211 0.0260085924385677 CCL4/CCL5/B2M/XCL1/CORO1A/FYN/CYBA/CALM1/CXCR4/CCL3/FXYD5/FLNA/EPB41/VAMP2/SLC9A3R1/PTPN6/MLLT6 17 GO:0097696 receptor signaling pathway via STAT 10/376 181/18722 0.00368460127750919 0.0260085924385677 CCL5/IL7R/PTPRC/FYN/JAK1/TNF/TGFB1/STAT1/IL10RA/STAT3 10 GO:0050850 positive regulation of calcium-mediated signaling 4/376 32/18722 0.00369133761314356 0.0260085924385677 CCL4/CD3E/TNF/CCL3 4 GO:0050807 regulation of synapse organization 11/376 211/18722 0.00370039090176195 0.0260085924385677 FYN/SRGN/TNF/CFL1/IL10RA/SEMA4D/YWHAZ/ABHD17A/TUBA1A/CDC42/ACTR2 11 GO:0009299 mRNA transcription 3/376 16/18722 0.00370496594221661 0.0260085924385677 DDX5/FLNA/STAT3 3 GO:0010819 regulation of T cell chemotaxis 3/376 16/18722 0.00370496594221661 0.0260085924385677 CCL5/XCL2/XCL1 3 GO:0045651 positive regulation of macrophage differentiation 3/376 16/18722 0.00370496594221661 0.0260085924385677 TGFB1/CASP8/ID2 3 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 3/376 16/18722 0.00370496594221661 0.0260085924385677 APOBEC3G/APOBEC3C/MPHOSPH8 3 GO:0050862 positive regulation of T cell receptor signaling pathway 3/376 16/18722 0.00370496594221661 0.0260085924385677 LCK/RAB29/CD81 3 GO:0051014 actin filament severing 3/376 16/18722 0.00370496594221661 0.0260085924385677 GMFG/CFL1/FMNL1 3 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 3/376 16/18722 0.00370496594221661 0.0260085924385677 PTPN22/TNFAIP3/NFKBIA 3 GO:0097202 activation of cysteine-type endopeptidase activity 3/376 16/18722 0.00370496594221661 0.0260085924385677 IFI16/CASP8/PYCARD 3 GO:1904683 regulation of metalloendopeptidase activity 3/376 16/18722 0.00370496594221661 0.0260085924385677 MBP/SORL1/STAT3 3 GO:1903426 regulation of reactive oxygen species biosynthetic process 5/376 52/18722 0.00381301349331167 0.0266988944320806 FYN/CYBA/RAB27A/STAT3/CFLAR 5 GO:0042100 B cell proliferation 7/376 99/18722 0.00381708064912842 0.0266988944320806 IL7R/PTPRC/IKZF3/RASGRP1/TYROBP/ATM/CD81 7 GO:2001235 positive regulation of apoptotic signaling pathway 8/376 126/18722 0.00395274678559974 0.0275980068363946 PTPRC/LCK/TNF/STK4/CYLD/SLC9A3R1/PYCARD/MCL1 8 GO:0002292 T cell differentiation involved in immune response 6/376 75/18722 0.00396084124504791 0.0276047838571235 RORA/EOMES/SPN/PTGER4/FCER1G/STAT3 6 GO:0001933 negative regulation of protein phosphorylation 15/376 342/18722 0.00404002455843074 0.0281060954468925 PTPRC/PTPN22/CALM1/DDIT4/TGFB1/CDKN2D/TNFAIP3/SEMA4D/DUSP1/TERF2IP/CBLB/SORL1/PTPN6/PYCARD/GADD45B 15 GO:0002431 Fc receptor mediated stimulatory signaling pathway 4/376 33/18722 0.00413494287254339 0.0286626315004575 PTPRC/FYN/FCER1G/CSK 4 GO:0045648 positive regulation of erythrocyte differentiation 4/376 33/18722 0.00413494287254339 0.0286626315004575 ETS1/STAT1/ISG15/STAT3 4 GO:0043113 receptor clustering 5/376 53/18722 0.00414221255232418 0.0286626315004575 ITGAL/ITGB2/ITGA4/FLNA/CD81 5 GO:0006305 DNA alkylation 6/376 76/18722 0.00422926939053071 0.029160887701613 FOS/KMT2A/KMT2E/MPHOSPH8/ATRX/ATF7IP 6 GO:0006306 DNA methylation 6/376 76/18722 0.00422926939053071 0.029160887701613 FOS/KMT2A/KMT2E/MPHOSPH8/ATRX/ATF7IP 6 GO:0010934 macrophage cytokine production 3/376 17/18722 0.00443251840436535 0.0304000156051606 SPON2/TGFB1/LAPTM5 3 GO:0010935 regulation of macrophage cytokine production 3/376 17/18722 0.00443251840436535 0.0304000156051606 SPON2/TGFB1/LAPTM5 3 GO:0045198 establishment of epithelial cell apical/basal polarity 3/376 17/18722 0.00443251840436535 0.0304000156051606 MSN/SLC9A3R1/CDC42 3 GO:0001706 endoderm formation 5/376 54/18722 0.00449120894844082 0.0307013731812082 DUSP2/EOMES/ITGB2/ITGA4/DUSP1 5 GO:0032677 regulation of interleukin-8 production 7/376 102/18722 0.00450022708823904 0.0307013731812082 CD2/PTPRC/TMSB4X/PTPN22/TNF/PYCARD/STAT3 7 GO:0035710 CD4-positive, alpha-beta T cell activation 7/376 102/18722 0.00450022708823904 0.0307013731812082 XCL1/RUNX3/RORA/SPN/PTGER4/STAT3/CD81 7 GO:0033002 muscle cell proliferation 12/376 248/18722 0.00452364154188172 0.0308068734179115 CCL5/CYBA/TNF/TGFB1/TNFAIP3/JUN/STAT1/ID2/PIM1/STAT3/CFLAR/SF1 12 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 4/376 34/18722 0.00461319581759499 0.0313616382336502 PYHIN1/DDX5/ATM/CD44 4 GO:0050803 regulation of synapse structure or activity 11/376 218/18722 0.00472510895791133 0.0320661947669114 FYN/SRGN/TNF/CFL1/IL10RA/SEMA4D/YWHAZ/ABHD17A/TUBA1A/CDC42/ACTR2 11 GO:0043087 regulation of GTPase activity 15/376 348/18722 0.00473560617316154 0.0320812481136381 CCL4/CCL5/XCL2/XCL1/GPR65/RASGRP1/TBC1D10C/ARAP2/CCL3/RGS1/CCL3L3/SEMA4D/CBLB/RASA2/PYCARD 15 GO:0032637 interleukin-8 production 7/376 103/18722 0.00474727177885131 0.032104150336909 CD2/PTPRC/TMSB4X/PTPN22/TNF/PYCARD/STAT3 7 GO:0016311 dephosphorylation 17/376 417/18722 0.00477025157074537 0.0322033533739343 PTPRC/PLEK/LCK/PTPN22/TNF/PTPN4/CALM1/TGFB1/PPP2R5C/SEMA4D/DUSP1/PTPN6/PTP4A2/PPP1R15A/PPP1R2/PPP1R12A/ROCK1 17 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 6/376 78/18722 0.00480610992187852 0.0323890016474422 LCK/TNF/CASP8/LAPTM5/PYCARD/CFLAR 6 GO:0038066 p38MAPK cascade 5/376 55/18722 0.00486063438365218 0.0326995802719656 PTPN22/ZFP36/CYLD/DUSP1/GADD45B 5 GO:0006892 post-Golgi vesicle-mediated transport 7/376 104/18722 0.00500439868954969 0.0335502507301125 LAPTM5/CSK/VAMP2/SORL1/VPS13C/MACF1/VAMP5 7 GO:0048661 positive regulation of smooth muscle cell proliferation 7/376 104/18722 0.00500439868954969 0.0335502507301125 CCL5/CYBA/TNF/TGFB1/JUN/STAT1/ID2 7 GO:0006959 humoral immune response 14/376 317/18722 0.00507303809050382 0.0339516797939591 GNLY/TRDC/PTPRC/HLA-A/TRBC1/HLA-E/TRBC2/SPON2/SH2D1A/TNF/RPL39/RPL30/PTPN6/CD81 14 GO:0045786 negative regulation of cell cycle 16/376 385/18722 0.00508787530835036 0.0339922703790649 ZFP36L2/RUNX3/TNF/BTG1/TGFB1/PRKACB/ATM/CDKN2D/TNFAIP3/RBL2/DUSP1/BTG2/SLC9A3R1/TAOK3/PRMT2/ATRX 16 GO:0060402 calcium ion transport into cytosol 9/376 160/18722 0.00511444422280899 0.034057924772359 PTPRC/XCL1/CORO1A/FYN/LCK/CYBA/CALM1/CCL3/PTPN6 9 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 6/376 79/18722 0.00511528057226141 0.034057924772359 CCL5/HCST/FYN/TNF/SEMA4D/PTPN6 6 GO:0010810 regulation of cell-substrate adhesion 11/376 221/18722 0.00522793590165644 0.0342452972277775 RAC2/CD3E/SKAP1/STK4/FLNA/LGALS1/PIK3R1/CDC42/MACF1/ACTG1/ROCK1 11 GO:0009896 positive regulation of catabolic process 19/376 492/18722 0.00523653973259233 0.0342452972277775 PYHIN1/ZFP36L2/MSN/TNF/PIP4K2A/TRIM22/MTDH/TNFAIP3/ZFP36/LAPTM5/PABPC1/CBLB/BTG2/SORL1/RNF19A/CD81/CNOT6L/TNRC6B/ROCK1 19 GO:0002223 stimulatory C-type lectin receptor signaling pathway 3/376 18/18722 0.00524063516285731 0.0342452972277775 KLRD1/FYN/TYROBP 3 GO:0002283 neutrophil activation involved in immune response 3/376 18/18722 0.00524063516285731 0.0342452972277775 ITGB2/TYROBP/FCER1G 3 GO:0002544 chronic inflammatory response 3/376 18/18722 0.00524063516285731 0.0342452972277775 CCL5/TNF/TNFAIP3 3 GO:0002643 regulation of tolerance induction 3/376 18/18722 0.00524063516285731 0.0342452972277775 HLA-B/CD3E/CBLB 3 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 3/376 18/18722 0.00524063516285731 0.0342452972277775 PTPRC/TNF/PTPN6 3 GO:0048535 lymph node development 3/376 18/18722 0.00524063516285731 0.0342452972277775 IL7R/LTB/TGFB1 3 GO:0050665 hydrogen peroxide biosynthetic process 3/376 18/18722 0.00524063516285731 0.0342452972277775 FYN/CYBA/STAT3 3 GO:1990840 response to lectin 3/376 18/18722 0.00524063516285731 0.0342452972277775 KLRD1/FYN/TYROBP 3 GO:1990858 cellular response to lectin 3/376 18/18722 0.00524063516285731 0.0342452972277775 KLRD1/FYN/TYROBP 3 GO:0045599 negative regulation of fat cell differentiation 5/376 56/18722 0.00525111630461 0.034256019663912 ZFP36L2/RORA/TNF/TGFB1/CCDC85B 5 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 7/376 105/18722 0.00527185992155185 0.0343335415059049 RAC2/PFN1/PIK3R1/ACTR3/CDC42EP3/CDC42/ACTR2 7 GO:0007346 regulation of mitotic cell cycle 18/376 457/18722 0.00532109208246308 0.0345960265428598 ZFP36L2/CCND2/TNF/BTG1/TGFB1/ATM/RBL2/PSME1/ID2/CYLD/DUSP1/KMT2E/BTG2/SLC9A3R1/PTPN6/TAOK3/CDC42/PRMT2 18 GO:1904951 positive regulation of establishment of protein localization 14/376 319/18722 0.00535575840773609 0.0347630884924244 GZMB/RAC2/FYN/TNF/ITGB2/TGFB1/FLNA/RAB29/TOMM7/PIK3R1/VAMP2/SORL1/CDC42/CD81 14 GO:0046328 regulation of JNK cascade 8/376 133/18722 0.00546853714783078 0.0354357549295054 PTPN22/RASGRP1/TNF/CYLD/TAOK3/PYCARD/CDC42/GADD45B 8 GO:0071496 cellular response to external stimulus 14/376 320/18722 0.00550180524415263 0.0355918118882996 PTPRC/CYBA/IRF1/ITGA4/IFI16/PTGER4/CNN2/NR4A2/CASP8/JUN/FOS/UCP2/XBP1/PIM1 14 GO:1905477 positive regulation of protein localization to membrane 7/376 106/18722 0.00554990839737494 0.0358431583997132 GZMB/FYN/TNF/ITGB2/PIK3R1/PRKCH/CD81 7 GO:0043547 positive regulation of GTPase activity 12/376 255/18722 0.00562428707466519 0.0362630822201791 CCL4/CCL5/XCL2/XCL1/GPR65/RASGRP1/TBC1D10C/ARAP2/CCL3/RGS1/CCL3L3/SEMA4D 12 GO:0051289 protein homotetramerization 5/376 57/18722 0.00566327718294463 0.0363698344068857 B2M/GBP5/EVL/GLS/SAMHD1 5 GO:0010923 negative regulation of phosphatase activity 4/376 36/18722 0.00567838704933312 0.0363698344068857 TNF/SEMA4D/PPP1R15A/ROCK1 4 GO:0051385 response to mineralocorticoid 4/376 36/18722 0.00567838704933312 0.0363698344068857 CYBA/CALM1/FOS/FOSB 4 GO:0090322 regulation of superoxide metabolic process 4/376 36/18722 0.00567838704933312 0.0363698344068857 CYBA/ITGB2/TYROBP/TGFB1 4 GO:0072331 signal transduction by p53 class mediator 9/376 163/18722 0.00576380633058727 0.0368560223284252 PYHIN1/DDIT4/IFI16/DDX5/ATM/CD44/SP100/PYCARD/ATRX 9 GO:0008037 cell recognition 11/376 225/18722 0.00596317240151776 0.0380680280986513 PRF1/TRDC/TRBC1/TRBC2/SPON2/NCR3/MSN/CXCR4/YWHAZ/EMB/CD81 11 GO:2001242 regulation of intrinsic apoptotic signaling pathway 9/376 164/18722 0.00599383256569055 0.038200824329031 LCK/CDKN2D/CD44/CYLD/XBP1/SLC9A3R1/IVNS1ABP/PYCARD/MCL1 9 GO:0031331 positive regulation of cellular catabolic process 17/376 427/18722 0.00600823518190191 0.0382297394579145 PYHIN1/ZFP36L2/MSN/TNF/PIP4K2A/TRIM22/MTDH/TNFAIP3/ZFP36/LAPTM5/PABPC1/BTG2/RNF19A/CD81/CNOT6L/TNRC6B/ROCK1 17 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 3/376 19/18722 0.00613163638384777 0.0386342942884717 HLA-E/ITGB2/TYROBP 3 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 3/376 19/18722 0.00613163638384777 0.0386342942884717 APOBEC3G/APOBEC3C/MPHOSPH8 3 GO:0048245 eosinophil chemotaxis 3/376 19/18722 0.00613163638384777 0.0386342942884717 CCL4/CCL5/CCL3 3 GO:0070233 negative regulation of T cell apoptotic process 3/376 19/18722 0.00613163638384777 0.0386342942884717 CCL5/IL7R/TSC22D3 3 GO:1903978 regulation of microglial cell activation 3/376 19/18722 0.00613163638384777 0.0386342942884717 CST7/PTPRC/CCL3 3 GO:2000269 regulation of fibroblast apoptotic process 3/376 19/18722 0.00613163638384777 0.0386342942884717 BTG1/STK17B/STK17A 3 GO:0032570 response to progesterone 4/376 37/18722 0.00626761523807357 0.0393630616653729 TXNIP/TGFB1/FOS/FOSB 4 GO:0090218 positive regulation of lipid kinase activity 4/376 37/18722 0.00626761523807357 0.0393630616653729 TGFB1/DGKZ/CDC42/CD81 4 GO:0050672 negative regulation of lymphocyte proliferation 6/376 83/18722 0.00649914350225128 0.0407511020569963 XCL1/SPN/TYROBP/ATM/CBLB/PTPN6 6 GO:0050684 regulation of mRNA processing 8/376 137/18722 0.00651382306177718 0.0407771637550672 CELF2/DDX5/MBNL1/SON/SRSF7/NCL/SF1/DDX17 8 GO:0007254 JNK cascade 9/376 167/18722 0.00672654655818453 0.0420409159886533 PTPN22/RASGRP1/TNF/PTGER4/CYLD/TAOK3/PYCARD/CDC42/GADD45B 9 GO:0032945 negative regulation of mononuclear cell proliferation 6/376 84/18722 0.00688379369441805 0.0428928794998035 XCL1/SPN/TYROBP/ATM/CBLB/PTPN6 6 GO:0010742 macrophage derived foam cell differentiation 4/376 38/18722 0.00689606811054905 0.0428928794998035 TGFB1/STAT1/PRKCH/NFKBIA 4 GO:0090077 foam cell differentiation 4/376 38/18722 0.00689606811054905 0.0428928794998035 TGFB1/STAT1/PRKCH/NFKBIA 4 GO:1902806 regulation of cell cycle G1/S phase transition 9/376 168/18722 0.00698545728355033 0.0433792419451243 CCND2/ATM/CDKN2D/RBL2/PSME1/ID2/KMT2E/PTPN6/PRMT2 9 GO:0051851 modulation by host of symbiont process 5/376 60/18722 0.00703596914928315 0.0436230087255556 CCL4/CCL5/CCL3/CFL1/JUN 5 GO:0007097 nuclear migration 3/376 20/18722 0.00710760121878885 0.0438566158006478 SUN2/SLC9A3R1/CDC42 3 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 3/376 20/18722 0.00710760121878885 0.0438566158006478 APOBEC3G/APOBEC3C/MPHOSPH8 3 GO:2000010 positive regulation of protein localization to cell surface 3/376 20/18722 0.00710760121878885 0.0438566158006478 CD247/TNF/TYROBP 3 GO:0032868 response to insulin 12/376 264/18722 0.0073410120655385 0.0451512985996854 PIP4K2A/STAT1/RAB8B/UCP2/PIK3R1/VAMP2/XBP1/SORL1/VPS13C/SRSF5/CFLAR/APRT 12 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 12/376 264/18722 0.0073410120655385 0.0451512985996854 CCL5/PTPRC/CD3E/FYN/TNF/ITGB2/TGFB1/CD44/SEMA4D/CBLB/PTPN6/CD81 12 GO:0071902 positive regulation of protein serine/threonine kinase activity 10/376 200/18722 0.00735237920423263 0.0451512985996854 RASGRP1/CCND2/TNF/CALM1/STK4/TGFB1/CSK/AKAP13/TAOK3/DAZAP2 10 GO:0043030 regulation of macrophage activation 5/376 61/18722 0.00754094710813525 0.046236028550671 CST7/PTPRC/RORA/CCL3/JUND 5 GO:0002347 response to tumor cell 4/376 39/18722 0.00756480331871692 0.0463090250553366 PRF1/HLA-A/TXNIP/LAPTM5 4 GO:0140694 non-membrane-bounded organelle assembly 15/376 367/18722 0.00760439351449147 0.0464779572060795 LCP1/MSN/TNF/RPL10/FLNA/BIN2/RPS27/KIF2A/RPL3/AKAP13/ACTG1/CNOT6L/CFLAR/DDX6/CENPC 15 GO:0007160 cell-matrix adhesion 11/376 233/18722 0.00767633286976691 0.0468437635753493 CD3E/CD96/SKAP1/ITGAL/ITGB2/ITGA4/CD44/PIK3R1/MACF1/ACTG1/ROCK1 11 GO:0035023 regulation of Rho protein signal transduction 6/376 86/18722 0.00770214404954076 0.0468645690824313 ARHGDIB/GPR65/CDC42SE2/ARHGEF3/CDC42SE1/AKAP13 6 GO:1903038 negative regulation of leukocyte cell-cell adhesion 8/376 141/18722 0.00770393045303451 0.0468645690824313 XCL1/RUNX3/PTPN22/SPN/IRF1/LAPTM5/CBLB/PTPN6 8 GO:0019722 calcium-mediated signaling 10/376 202/18722 0.00786153165722758 0.0477483309902145 CCL4/PTPRC/CD3E/PLEK/TBC1D10C/LAT/TNF/CALM1/CXCR4/CCL3 10 GO:2000045 regulation of G1/S transition of mitotic cell cycle 8/376 142/18722 0.00802546684814531 0.0486370842365269 CCND2/ATM/RBL2/PSME1/ID2/KMT2E/PTPN6/PRMT2 8 GO:0032613 interleukin-10 production 5/376 62/18722 0.00807061810686111 0.0486370842365269 XCL1/TYROBP/ISG15/PYCARD/STAT3 5 GO:0032653 regulation of interleukin-10 production 5/376 62/18722 0.00807061810686111 0.0486370842365269 XCL1/TYROBP/ISG15/PYCARD/STAT3 5 GO:0048488 synaptic vesicle endocytosis 5/376 62/18722 0.00807061810686111 0.0486370842365269 CALM1/ACTB/VAMP2/ACTG1/ROCK1 5 GO:0140238 presynaptic endocytosis 5/376 62/18722 0.00807061810686111 0.0486370842365269 CALM1/ACTB/VAMP2/ACTG1/ROCK1 5 GO:0051262 protein tetramerization 6/376 87/18722 0.00813658843624506 0.0489338760380779 B2M/GBP5/EVL/STK4/GLS/SAMHD1 6 GO:0045930 negative regulation of mitotic cell cycle 11/376 235/18722 0.00815926653177241 0.0489338760380779 ZFP36L2/TNF/BTG1/TGFB1/ATM/RBL2/DUSP1/BTG2/SLC9A3R1/TAOK3/PRMT2 11 GO:0070269 pyroptosis 3/376 21/18722 0.00817037878622874 0.0489338760380779 GZMA/GZMB/CASP8 3 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 3/376 21/18722 0.00817037878622874 0.0489338760380779 FYN/STAT3/CFLAR 3 GO:0043001 Golgi to plasma membrane protein transport 4/376 40/18722 0.00827484156720443 0.0492550093285978 CSK/VAMP2/MACF1/VAMP5 4 GO:0070266 necroptotic process 4/376 40/18722 0.00827484156720443 0.0492550093285978 TNF/CASP8/CYLD/CFLAR 4 GO:0150077 regulation of neuroinflammatory response 4/376 40/18722 0.00827484156720443 0.0492550093285978 CST7/PTPRC/TNF/CCL3 4 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 4/376 40/18722 0.00827484156720443 0.0492550093285978 ETS1/TNF/ITGB2/ITGA4 4 GO:0009144 purine nucleoside triphosphate metabolic process 6/376 88/18722 0.00858837142060733 0.0510428516178733 TMSB4X/GIMAP7/TGFB1/SAMHD1/STAT3/GUK1 6 GO:0051259 protein complex oligomerization 11/376 238/18722 0.00892754930730515 0.0529774174055244 PRF1/B2M/GBP5/ALOX5AP/EVL/RNF213/STK4/ISG15/GLS/SAMHD1/PYCARD 11 GO:0032733 positive regulation of interleukin-10 production 4/376 41/18722 0.00902716569071723 0.0534866468677817 XCL1/ISG15/PYCARD/STAT3 4 GO:0046330 positive regulation of JNK cascade 6/376 89/18722 0.00905785916197043 0.0535865713780693 RASGRP1/TNF/TAOK3/PYCARD/CDC42/GADD45B 6 GO:0051403 stress-activated MAPK cascade 11/376 239/18722 0.00919570702835379 0.0539928179707665 PTPN22/RASGRP1/TNF/PTGER4/ZFP36/CYLD/DUSP1/TAOK3/PYCARD/CDC42/GADD45B 11 GO:0030888 regulation of B cell proliferation 5/376 64/18722 0.00920634483183858 0.0539928179707665 PTPRC/IKZF3/TYROBP/ATM/CD81 5 GO:0045670 regulation of osteoclast differentiation 5/376 64/18722 0.00920634483183858 0.0539928179707665 TNF/CCL3/TYROBP/FOS/PIK3R1 5 GO:1903409 reactive oxygen species biosynthetic process 5/376 64/18722 0.00920634483183858 0.0539928179707665 FYN/CYBA/RAB27A/STAT3/CFLAR 5 GO:0002220 innate immune response activating cell surface receptor signaling pathway 3/376 22/18722 0.00932159876708202 0.0539928179707665 KLRD1/FYN/TYROBP 3 GO:0010310 regulation of hydrogen peroxide metabolic process 3/376 22/18722 0.00932159876708202 0.0539928179707665 RAC2/FYN/STAT3 3 GO:0035089 establishment of apical/basal cell polarity 3/376 22/18722 0.00932159876708202 0.0539928179707665 MSN/SLC9A3R1/CDC42 3 GO:0044346 fibroblast apoptotic process 3/376 22/18722 0.00932159876708202 0.0539928179707665 BTG1/STK17B/STK17A 3 GO:0051220 cytoplasmic sequestering of protein 3/376 22/18722 0.00932159876708202 0.0539928179707665 TMSB4X/FLNA/NFKBIA 3 GO:0051412 response to corticosterone 3/376 22/18722 0.00932159876708202 0.0539928179707665 CALM1/FOS/FOSB 3 GO:0060965 negative regulation of gene silencing by miRNA 3/376 22/18722 0.00932159876708202 0.0539928179707665 TNF/TGFB1/STAT3 3 GO:0071404 cellular response to low-density lipoprotein particle stimulus 3/376 22/18722 0.00932159876708202 0.0539928179707665 ITGB2/FCER1G/CD81 3 GO:0072574 hepatocyte proliferation 3/376 22/18722 0.00932159876708202 0.0539928179707665 TNFAIP3/XBP1/CFLAR 3 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 3/376 22/18722 0.00932159876708202 0.0539928179707665 TNFAIP3/XBP1/CFLAR 3 GO:0042542 response to hydrogen peroxide 8/376 146/18722 0.00941319951433605 0.0543608764799586 ETS1/TXNIP/KLF2/FYN/TNFAIP3/JUN/STAT1/DUSP1 8 GO:0045580 regulation of T cell differentiation 8/376 146/18722 0.00941319951433605 0.0543608764799586 IL7R/CD2/PTPRC/RUNX3/PRDM1/RASGRP1/IRF1/XBP1 8 GO:0034249 negative regulation of cellular amide metabolic process 12/376 273/18722 0.00944545092131135 0.0544659558334546 GZMB/ZFP36L2/ZFP36/PABPC1/BTG2/SORL1/STAT3/NCL/CNOT6L/DDX6/TNRC6B/ROCK1 12 GO:0046596 regulation of viral entry into host cell 4/376 42/18722 0.00982271985280314 0.0565572651257239 IFITM1/IFITM2/TRIM22/LGALS1 4 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 10/376 209/18722 0.00986018528127431 0.0566887506898189 LCK/TNF/CDKN2D/CD44/CASP8/LAPTM5/CARD16/RPS6KA3/PYCARD/CFLAR 10 GO:0048015 phosphatidylinositol-mediated signaling 9/376 178/18722 0.0100139953129384 0.0574877508705724 CCL5/HCST/FYN/RASGRP1/TNF/SEMA4D/PIK3R1/SLC9A3R1/PTPN6 9 GO:2001056 positive regulation of cysteine-type endopeptidase activity 8/376 148/18722 0.0101706078290604 0.0583004516828535 FYN/LCK/TNF/IFI16/CASP8/LAPTM5/PYCARD/CFLAR 8 GO:0014015 positive regulation of gliogenesis 5/376 66/18722 0.010447663481843 0.0597119409913595 TNF/CXCR4/TGFB1/ID2/PRKCH 5 GO:0045600 positive regulation of fat cell differentiation 5/376 66/18722 0.010447663481843 0.0597119409913595 STK4/ZFP36/ID2/XBP1/PIM1 5 GO:0002758 innate immune response-activating signal transduction 3/376 23/18722 0.0105626816252643 0.0598576665976351 KLRD1/FYN/TYROBP 3 GO:0051457 maintenance of protein location in nucleus 3/376 23/18722 0.0105626816252643 0.0598576665976351 SYNE1/SP100/SUN2 3 GO:0060396 growth hormone receptor signaling pathway 3/376 23/18722 0.0105626816252643 0.0598576665976351 PIK3R1/STAT3/LEPROTL1 3 GO:0072576 liver morphogenesis 3/376 23/18722 0.0105626816252643 0.0598576665976351 TNFAIP3/XBP1/CFLAR 3 GO:2000810 regulation of bicellular tight junction assembly 3/376 23/18722 0.0105626816252643 0.0598576665976351 TNF/PRKCH/ROCK1 3 GO:0051592 response to calcium ion 8/376 149/18722 0.010565843600718 0.0598576665976351 TXNIP/ALOX5AP/CALM1/JUNB/FOS/JUND/DUSP1/FOSB 8 GO:0002861 regulation of inflammatory response to antigenic stimulus 4/376 43/18722 0.010662408859526 0.0601409524463801 HLA-E/FYN/TNF/CD81 4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 4/376 43/18722 0.010662408859526 0.0601409524463801 DDIT4/IFI16/CD44/PYCARD 4 GO:0098927 vesicle-mediated transport between endosomal compartments 4/376 43/18722 0.010662408859526 0.0601409524463801 CORO1A/MSN/FLNA/SORL1 4 GO:0071901 negative regulation of protein serine/threonine kinase activity 7/376 120/18722 0.0106966000818818 0.060246112379785 PTPN22/CDKN2D/TNFAIP3/DUSP1/SORL1/PTPN6/PYCARD 7 GO:0048660 regulation of smooth muscle cell proliferation 9/376 180/18722 0.0107229187519609 0.0603066910941198 CCL5/CYBA/TNF/TGFB1/TNFAIP3/JUN/STAT1/ID2/SF1 9 GO:0006469 negative regulation of protein kinase activity 10/376 212/18722 0.0108266133384101 0.0607136420931102 PTPRC/PTPN22/CDKN2D/TNFAIP3/DUSP1/CBLB/SORL1/PTPN6/PYCARD/GADD45B 10 GO:0043523 regulation of neuron apoptotic process 10/376 212/18722 0.0108266133384101 0.0607136420931102 CORO1A/FYN/TNF/CCL3/TYROBP/NR4A2/JUN/BTG2/CDC42/MCL1 10 GO:0017148 negative regulation of translation 11/376 245/18722 0.0109376985185068 0.061247950519095 GZMB/ZFP36L2/ZFP36/PABPC1/BTG2/STAT3/NCL/CNOT6L/DDX6/TNRC6B/ROCK1 11 GO:1902117 positive regulation of organelle assembly 5/376 67/18722 0.0111092852719792 0.0620897544892633 LCP1/MSN/TNF/PIP4K2A/CNOT6L 5 GO:0051591 response to cAMP 6/376 93/18722 0.0111200747394964 0.0620897544892633 JUN/STAT1/FOS/DUSP1/RAP1B/FOSB 6 GO:0002455 humoral immune response mediated by circulating immunoglobulin 7/376 121/18722 0.0111639239692399 0.0622448998284961 TRDC/PTPRC/TRBC1/TRBC2/TNF/PTPN6/CD81 7 GO:0048017 inositol lipid-mediated signaling 9/376 182/18722 0.0114688904319319 0.0636704160798513 CCL5/HCST/FYN/RASGRP1/TNF/SEMA4D/PIK3R1/SLC9A3R1/PTPN6 9 GO:0051260 protein homooligomerization 9/376 182/18722 0.0114688904319319 0.0636704160798513 PRF1/B2M/GBP5/ALOX5AP/EVL/RNF213/GLS/SAMHD1/PYCARD 9 GO:0060401 cytosolic calcium ion transport 9/376 182/18722 0.0114688904319319 0.0636704160798513 PTPRC/XCL1/CORO1A/FYN/LCK/CYBA/CALM1/CCL3/PTPN6 9 GO:0021762 substantia nigra development 4/376 44/18722 0.0115470975818628 0.0638302469753472 MBP/CALM1/ACTB/CDC42 4 GO:0042554 superoxide anion generation 4/376 44/18722 0.0115470975818628 0.0638302469753472 CYBA/ITGB2/TYROBP/TGFB1 4 GO:0150076 neuroinflammatory response 4/376 44/18722 0.0115470975818628 0.0638302469753472 CST7/PTPRC/TNF/CCL3 4 GO:0031098 stress-activated protein kinase signaling cascade 11/376 247/18722 0.011571246783949 0.0638726229170971 PTPN22/RASGRP1/TNF/PTGER4/ZFP36/CYLD/DUSP1/TAOK3/PYCARD/CDC42/GADD45B 11 GO:0019080 viral gene expression 6/376 94/18722 0.0116834688548496 0.0643088662109973 CCL4/CCL5/CCL3/JUN/ZFP36/MGAT4A 6 GO:0032091 negative regulation of protein binding 6/376 94/18722 0.0116834688548496 0.0643088662109973 B2M/ITGA4/ACTB/CARD16/SORL1/ROCK1 6 GO:0050871 positive regulation of B cell activation 8/376 152/18722 0.0118198816689752 0.0645553750740018 TRDC/PTPRC/TRBC1/TRBC2/TGFB1/XBP1/SH3KBP1/CD81 8 GO:0001779 natural killer cell differentiation 3/376 24/18722 0.0118948484652483 0.0645553750740018 PTPRC/PRDM1/RASGRP1 3 GO:0030859 polarized epithelial cell differentiation 3/376 24/18722 0.0118948484652483 0.0645553750740018 MSN/SLC9A3R1/CDC42 3 GO:0036010 protein localization to endosome 3/376 24/18722 0.0118948484652483 0.0645553750740018 MSN/ABHD17A/SORL1 3 GO:0045649 regulation of macrophage differentiation 3/376 24/18722 0.0118948484652483 0.0645553750740018 TGFB1/CASP8/ID2 3 GO:0051647 nucleus localization 3/376 24/18722 0.0118948484652483 0.0645553750740018 SUN2/SLC9A3R1/CDC42 3 GO:0060149 negative regulation of posttranscriptional gene silencing 3/376 24/18722 0.0118948484652483 0.0645553750740018 TNF/TGFB1/STAT3 3 GO:0060967 negative regulation of gene silencing by RNA 3/376 24/18722 0.0118948484652483 0.0645553750740018 TNF/TGFB1/STAT3 3 GO:0061162 establishment of monopolar cell polarity 3/376 24/18722 0.0118948484652483 0.0645553750740018 MSN/SLC9A3R1/CDC42 3 GO:0071378 cellular response to growth hormone stimulus 3/376 24/18722 0.0118948484652483 0.0645553750740018 PIK3R1/STAT3/LEPROTL1 3 GO:0006887 exocytosis 14/376 352/18722 0.0121409774615936 0.0657990037254199 CCL5/RAC2/CORO1A/PLEK/HLA-F/RASGRP1/LAT/CALM1/ITGB2/CCL3/RAB27A/RAB8B/VAMP2/RAP1B 14 GO:0048659 smooth muscle cell proliferation 9/376 184/18722 0.0122530413492516 0.066294900789386 CCL5/CYBA/TNF/TGFB1/TNFAIP3/JUN/STAT1/ID2/SF1 9 GO:0002532 production of molecular mediator involved in inflammatory response 6/376 95/18722 0.0122666951912232 0.066294900789386 GBP5/ALOX5AP/TNF/GPSM3/PYCARD/STAT3 6 GO:0035305 negative regulation of dephosphorylation 4/376 45/18722 0.0124776104808888 0.0671796553229411 TNF/SEMA4D/PPP1R15A/ROCK1 4 GO:0071364 cellular response to epidermal growth factor stimulus 4/376 45/18722 0.0124776104808888 0.0671796553229411 ZFP36L2/ZFP36/NCL/CFLAR 4 GO:0002287 alpha-beta T cell activation involved in immune response 5/376 69/18722 0.0125170867466228 0.0671796553229411 RORA/EOMES/SPN/PTGER4/STAT3 5 GO:0002293 alpha-beta T cell differentiation involved in immune response 5/376 69/18722 0.0125170867466228 0.0671796553229411 RORA/EOMES/SPN/PTGER4/STAT3 5 GO:0050688 regulation of defense response to virus 5/376 69/18722 0.0125170867466228 0.0671796553229411 APOBEC3G/PTPN22/TNFAIP3/STAT1/PYCARD 5 GO:0050808 synapse organization 16/376 426/18722 0.0127082850513241 0.0681114862709277 FYN/SRGN/TNF/FLNA/RAB29/CFL1/ACTB/IL10RA/PFN1/SEMA4D/YWHAZ/ABHD17A/TUBA1A/CDC42/ACTR2/ACTG1 16 GO:0007204 positive regulation of cytosolic calcium ion concentration 13/376 319/18722 0.0127598904478823 0.0682936125490939 PTPRC/CD52/XCL1/CORO1A/GPR65/FYN/LCK/CYBA/CALM1/CXCR4/PTGER4/CCL3/PTPN6 13 GO:1901655 cellular response to ketone 6/376 96/18722 0.0128700943824816 0.068788435492574 KLF2/GNG2/MSN/DDIT4/PTGER4/CFLAR 6 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 13/376 320/18722 0.0130672360754018 0.0696036163653938 CELF2/DDX5/MBNL1/PABPC1/SON/SRSF7/PNN/NCL/C9orf78/SRSF5/SCAF11/SF1/DDX17 13 GO:0000398 mRNA splicing, via spliceosome 13/376 320/18722 0.0130672360754018 0.0696036163653938 CELF2/DDX5/MBNL1/PABPC1/SON/SRSF7/PNN/NCL/C9orf78/SRSF5/SCAF11/SF1/DDX17 13 GO:0031345 negative regulation of cell projection organization 9/376 186/18722 0.013076498764905 0.0696036163653938 B2M/FYN/EVL/VIM/FLNA/RAB29/SEMA4D/LGALS1/ODF2L 9 GO:1904375 regulation of protein localization to cell periphery 7/376 125/18722 0.0131819375646089 0.0700685981657879 TNF/TGFB1/EPB41/ACTB/PIK3R1/PRKCH/CSK 7 GO:0032753 positive regulation of interleukin-4 production 3/376 25/18722 0.0133191305377718 0.0702199058964161 CD3E/HLA-E/FCER1G 3 GO:0042832 defense response to protozoan 3/376 25/18722 0.0133191305377718 0.0702199058964161 GBP4/GBP2/LYST 3 GO:0061339 establishment or maintenance of monopolar cell polarity 3/376 25/18722 0.0133191305377718 0.0702199058964161 MSN/SLC9A3R1/CDC42 3 GO:1901798 positive regulation of signal transduction by p53 class mediator 3/376 25/18722 0.0133191305377718 0.0702199058964161 PYHIN1/DDX5/ATM 3 GO:1903901 negative regulation of viral life cycle 3/376 25/18722 0.0133191305377718 0.0702199058964161 IFITM1/IFITM2/BST2 3 GO:1905048 regulation of metallopeptidase activity 3/376 25/18722 0.0133191305377718 0.0702199058964161 MBP/SORL1/STAT3 3 GO:0061028 establishment of endothelial barrier 4/376 46/18722 0.0134547312300535 0.0708384286908386 MSN/TNF/RAP1B/ROCK1 4 GO:0035335 peptidyl-tyrosine dephosphorylation 6/376 97/18722 0.0134940024378756 0.0709487916509742 PTPRC/PTPN22/PTPN4/DUSP1/PTPN6/PTP4A2 6 GO:0002064 epithelial cell development 10/376 220/18722 0.0137557216766668 0.0722268583971324 PRDM1/MSN/TNF/CXCR4/VIM/FLNA/RAP1B/SLC9A3R1/ATRX/ROCK1 10 GO:0033674 positive regulation of kinase activity 17/376 467/18722 0.0138070049012534 0.0723980297596169 CCL5/PTPRC/RASGRP1/CCND2/LAT/TNF/CALM1/LCP2/STK4/TGFB1/DGKZ/CSK/AKAP13/TAOK3/CDC42/CD81/DAZAP2 17 GO:0001837 epithelial to mesenchymal transition 8/376 157/18722 0.0141486355972983 0.0740891391074741 EOMES/S100A4/DDX5/TGFB1/FLNA/GLIPR2/DDX17/ROCK1 8 GO:0006911 phagocytosis, engulfment 7/376 127/18722 0.0142835581378881 0.0746947203567022 TRDC/RAC2/TRBC1/TRBC2/ITGB2/BIN2/CDC42 7 GO:0000375 RNA splicing, via transesterification reactions 13/376 324/18722 0.0143540320328294 0.0749453772158576 CELF2/DDX5/MBNL1/PABPC1/SON/SRSF7/PNN/NCL/C9orf78/SRSF5/SCAF11/SF1/DDX17 13 GO:0046578 regulation of Ras protein signal transduction 9/376 189/18722 0.0143878369080218 0.0749453772158576 ARHGDIB/GPR65/RASGRP1/CYTH1/CDC42SE2/ARHGEF3/CDC42SE1/AKAP13/RASA2 9 GO:0051924 regulation of calcium ion transport 11/376 255/18722 0.0143895124254447 0.0749453772158576 CCL4/CCL5/XCL1/CORO1A/FYN/CYBA/CALM1/CXCR4/CCL3/EPB41/PTPN6 11 GO:0045911 positive regulation of DNA recombination 4/376 47/18722 0.014479202429086 0.075009237182765 PTPRC/TGFB1/WAS/ACTR2 4 GO:0046677 response to antibiotic 4/376 47/18722 0.014479202429086 0.075009237182765 CRIP1/JAK1/CASP8/ACTR2 4 GO:0097300 programmed necrotic cell death 4/376 47/18722 0.014479202429086 0.075009237182765 TNF/CASP8/CYLD/CFLAR 4 GO:1900744 regulation of p38MAPK cascade 4/376 47/18722 0.014479202429086 0.075009237182765 PTPN22/CYLD/DUSP1/GADD45B 4 GO:0000302 response to reactive oxygen species 10/376 222/18722 0.0145728655407103 0.0753936635116855 ETS1/TXNIP/KLF2/FYN/TNFAIP3/JUN/STAT1/FOS/UCP2/DUSP1 10 GO:0043488 regulation of mRNA stability 8/376 158/18722 0.0146518101828826 0.075701019278227 ZFP36L2/VIM/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 8 GO:0044403 biological process involved in symbiotic interaction 12/376 290/18722 0.014671666410441 0.0757026728900915 CCL4/CCL5/IFITM1/IFITM2/CXCR4/SELPLG/CCL3/TRIM22/CFL1/JUN/LGALS1/CD81 12 GO:0071559 response to transforming growth factor beta 11/376 256/18722 0.0147752748283847 0.0758035777619062 ZFP36L2/XCL1/RUNX3/FYN/TGFB1/JUN/FOS/ZEB2/STAT3/CFLAR/ROCK1 11 GO:0001562 response to protozoan 3/376 26/18722 0.0148363784046071 0.0758035777619062 GBP4/GBP2/LYST 3 GO:0032515 negative regulation of phosphoprotein phosphatase activity 3/376 26/18722 0.0148363784046071 0.0758035777619062 TNF/PPP1R15A/ROCK1 3 GO:0045672 positive regulation of osteoclast differentiation 3/376 26/18722 0.0148363784046071 0.0758035777619062 TNF/TYROBP/FOS 3 GO:0060544 regulation of necroptotic process 3/376 26/18722 0.0148363784046071 0.0758035777619062 CASP8/CYLD/CFLAR 3 GO:0002534 cytokine production involved in inflammatory response 5/376 72/18722 0.0148477201345256 0.0758035777619062 GBP5/TNF/GPSM3/PYCARD/STAT3 5 GO:0071479 cellular response to ionizing radiation 5/376 72/18722 0.0148477201345256 0.0758035777619062 CCND2/CYBA/IFI16/ATM/EEF1D 5 GO:1900015 regulation of cytokine production involved in inflammatory response 5/376 72/18722 0.0148477201345256 0.0758035777619062 GBP5/TNF/GPSM3/PYCARD/STAT3 5 GO:2001234 negative regulation of apoptotic signaling pathway 10/376 224/18722 0.0154257467034913 0.0786510111526696 FYN/TNF/CDKN2D/CD44/TNFAIP3/NR4A2/XBP1/IVNS1ABP/CFLAR/MCL1 10 GO:0048732 gland development 16/376 436/18722 0.0155097932794072 0.0789756228090707 ETS1/CRIP1/MSN/TNF/TGFB1/LBH/TNFAIP3/ID2/UCP2/XBP1/RPL19/SLC9A3R1/CDC42/SRSF5/CFLAR/APRT 16 GO:0033628 regulation of cell adhesion mediated by integrin 4/376 48/18722 0.0155517254042922 0.0789815674202256 CCL5/CD3E/SKAP1/PTPN6 4 GO:0045912 negative regulation of carbohydrate metabolic process 4/376 48/18722 0.0155517254042922 0.0789815674202256 PLEK/DDIT4/TGFB1/STAT3 4 GO:0032872 regulation of stress-activated MAPK cascade 9/376 192/18722 0.0157938928054008 0.0801064589279164 PTPN22/RASGRP1/TNF/CYLD/DUSP1/TAOK3/PYCARD/CDC42/GADD45B 9 GO:0150115 cell-substrate junction organization 6/376 101/18722 0.0162012690957445 0.0815265405305655 RAB8B/TLN1/PIK3R1/MACF1/ACTG1/ROCK1 6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway 2/376 10/18722 0.0162718207825353 0.0815265405305655 GNG2/SLC9A3R1 2 GO:0010728 regulation of hydrogen peroxide biosynthetic process 2/376 10/18722 0.0162718207825353 0.0815265405305655 FYN/STAT3 2 GO:0030214 hyaluronan catabolic process 2/376 10/18722 0.0162718207825353 0.0815265405305655 TGFB1/CD44 2 GO:0033089 positive regulation of T cell differentiation in thymus 2/376 10/18722 0.0162718207825353 0.0815265405305655 IL7R/RASGRP1 2 GO:0042989 sequestering of actin monomers 2/376 10/18722 0.0162718207825353 0.0815265405305655 TMSB4X/TMSB10 2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 2/376 10/18722 0.0162718207825353 0.0815265405305655 PTPRC/CSK 2 GO:0070383 DNA cytosine deamination 2/376 10/18722 0.0162718207825353 0.0815265405305655 APOBEC3G/APOBEC3C 2 GO:1902946 protein localization to early endosome 2/376 10/18722 0.0162718207825353 0.0815265405305655 MSN/SORL1 2 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 9/376 193/18722 0.0162842689988794 0.0815265405305655 CCL5/PTPRC/CD3E/FYN/TNF/TGFB1/CD44/SEMA4D/CD81 9 GO:0010528 regulation of transposition 3/376 27/18722 0.0164472707729938 0.0818140876063555 APOBEC3G/MYBL1/APOBEC3C 3 GO:0010529 negative regulation of transposition 3/376 27/18722 0.0164472707729938 0.0818140876063555 APOBEC3G/MYBL1/APOBEC3C 3 GO:0060142 regulation of syncytium formation by plasma membrane fusion 3/376 27/18722 0.0164472707729938 0.0818140876063555 CD53/TYROBP/CFLAR 3 GO:0070861 regulation of protein exit from endoplasmic reticulum 3/376 27/18722 0.0164472707729938 0.0818140876063555 SORL1/CD81/GCC2 3 GO:1903421 regulation of synaptic vesicle recycling 3/376 27/18722 0.0164472707729938 0.0818140876063555 CALM1/VAMP2/ROCK1 3 GO:0002437 inflammatory response to antigenic stimulus 5/376 74/18722 0.0165529912546526 0.0821291179408181 HLA-E/FYN/RASGRP1/TNF/CD81 5 GO:0120192 tight junction assembly 5/376 74/18722 0.0165529912546526 0.0821291179408181 TNF/MTDH/PRKCH/ACTG1/ROCK1 5 GO:0030225 macrophage differentiation 4/376 49/18722 0.0166729600902212 0.0823028284708371 TGFB1/CASP8/ID2/CDC42 4 GO:0052372 modulation by symbiont of entry into host 4/376 49/18722 0.0166729600902212 0.0823028284708371 IFITM1/IFITM2/TRIM22/LGALS1 4 GO:0070849 response to epidermal growth factor 4/376 49/18722 0.0166729600902212 0.0823028284708371 ZFP36L2/ZFP36/NCL/CFLAR 4 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 4/376 49/18722 0.0166729600902212 0.0823028284708371 STK4/TNFAIP3/SP100/CFLAR 4 GO:0071214 cellular response to abiotic stimulus 13/376 331/18722 0.0168371021721377 0.0829018690178318 CRIP1/CCND2/CYBA/IRF1/IFI16/PTGER4/ATM/CNN2/RCSD1/CASP8/PIK3R1/EEF1D/CARD16 13 GO:0104004 cellular response to environmental stimulus 13/376 331/18722 0.0168371021721377 0.0829018690178318 CRIP1/CCND2/CYBA/IRF1/IFI16/PTGER4/ATM/CNN2/RCSD1/CASP8/PIK3R1/EEF1D/CARD16 13 GO:0010522 regulation of calcium ion transport into cytosol 6/376 102/18722 0.0169325842212136 0.0832661977883283 XCL1/CORO1A/FYN/CYBA/CALM1/PTPN6 6 GO:0051258 protein polymerization 12/376 296/18722 0.0169633176016347 0.0833116041905379 TMSB4X/CORO1A/EVL/GMFG/WAS/TMSB10/PFN1/PYCARD/ACTR3/ARPC5L/CDC42EP3/ACTR2 12 GO:0070302 regulation of stress-activated protein kinase signaling cascade 9/376 195/18722 0.0172983745749925 0.0848496221241721 PTPN22/RASGRP1/TNF/CYLD/DUSP1/TAOK3/PYCARD/CDC42/GADD45B 9 GO:0036465 synaptic vesicle recycling 5/376 75/18722 0.017452430541053 0.0854970522712774 CALM1/ACTB/VAMP2/ACTG1/ROCK1 5 GO:0002448 mast cell mediated immunity 4/376 50/18722 0.0178435249878904 0.0873026001617112 RAC2/SPON2/RASGRP1/LAT 4 GO:0002313 mature B cell differentiation involved in immune response 3/376 28/18722 0.018152323010034 0.0880353587783251 ITM2A/LGALS1/XBP1 3 GO:0002675 positive regulation of acute inflammatory response 3/376 28/18722 0.018152323010034 0.0880353587783251 HLA-E/ALOX5AP/TNF 3 GO:0032438 melanosome organization 3/376 28/18722 0.018152323010034 0.0880353587783251 RAB29/ZEB2/LYST 3 GO:0038094 Fc-gamma receptor signaling pathway 3/376 28/18722 0.018152323010034 0.0880353587783251 PTPRC/FYN/FCER1G 3 GO:0061082 myeloid leukocyte cytokine production 3/376 28/18722 0.018152323010034 0.0880353587783251 SPON2/TGFB1/LAPTM5 3 GO:1902624 positive regulation of neutrophil migration 3/376 28/18722 0.018152323010034 0.0880353587783251 RAC2/XCL1/CD99 3 GO:1903649 regulation of cytoplasmic transport 3/376 28/18722 0.018152323010034 0.0880353587783251 MSN/RAB29/SORL1 3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 5/376 76/18722 0.0183836390727799 0.0889345835293661 DDIT4/IFI16/DDX5/CD44/PYCARD 5 GO:2000379 positive regulation of reactive oxygen species metabolic process 5/376 76/18722 0.0183836390727799 0.0889345835293661 CYBA/ITGB2/TYROBP/TGFB1/RAB27A 5 GO:1903076 regulation of protein localization to plasma membrane 6/376 104/18722 0.0184627587366209 0.0892059726987607 TNF/TGFB1/ACTB/PIK3R1/PRKCH/CSK 6 GO:0031099 regeneration 9/376 198/18722 0.0189049309776252 0.0912286519779548 LCP1/HOPX/TXK/FLNA/UCP2/RPL19/CD81/SRSF5/CFLAR 9 GO:0032873 negative regulation of stress-activated MAPK cascade 4/376 51/18722 0.0190639971949582 0.0917676883608235 PTPN22/CYLD/DUSP1/TAOK3 4 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 4/376 51/18722 0.0190639971949582 0.0917676883608235 PTPN22/CYLD/DUSP1/TAOK3 4 GO:0061013 regulation of mRNA catabolic process 8/376 166/18722 0.0191557653969766 0.0920950259470028 ZFP36L2/VIM/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 8 GO:0006402 mRNA catabolic process 10/376 232/18722 0.019212304548597 0.0922523917296326 ZFP36L2/VIM/DDX5/ATM/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 10 GO:0040029 regulation of gene expression, epigenetic 6/376 105/18722 0.0192622071496554 0.0923775404763798 KLF2/IFI16/XIST/EPC1/MPHOSPH8/ATF7IP 6 GO:0007492 endoderm development 5/376 77/18722 0.0193470237797438 0.0925211426562257 DUSP2/EOMES/ITGB2/ITGA4/DUSP1 5 GO:0051056 regulation of small GTPase mediated signal transduction 12/376 302/18722 0.019515003225444 0.0925211426562257 ARHGDIB/GPR65/RASGRP1/ARHGAP30/TAGAP/ARHGEF1/CYTH1/CDC42SE2/ARHGEF3/CDC42SE1/AKAP13/RASA2 12 GO:0001787 natural killer cell proliferation 2/376 11/18722 0.0196264204550755 0.0925211426562257 HLA-E/PTPN22 2 GO:0002357 defense response to tumor cell 2/376 11/18722 0.0196264204550755 0.0925211426562257 PRF1/LAPTM5 2 GO:0002645 positive regulation of tolerance induction 2/376 11/18722 0.0196264204550755 0.0925211426562257 CD3E/CBLB 2 GO:0002725 negative regulation of T cell cytokine production 2/376 11/18722 0.0196264204550755 0.0925211426562257 XCL1/HLA-F 2 GO:0042789 mRNA transcription by RNA polymerase II 2/376 11/18722 0.0196264204550755 0.0925211426562257 FLNA/STAT3 2 GO:0045060 negative thymic T cell selection 2/376 11/18722 0.0196264204550755 0.0925211426562257 PTPRC/CD3E 2 GO:0048102 autophagic cell death 2/376 11/18722 0.0196264204550755 0.0925211426562257 CDKN2D/LAPTM5 2 GO:0048103 somatic stem cell division 2/376 11/18722 0.0196264204550755 0.0925211426562257 ZFP36L2/LBH 2 GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly 2/376 11/18722 0.0196264204550755 0.0925211426562257 MPHOSPH8/ATF7IP 2 GO:1902033 regulation of hematopoietic stem cell proliferation 2/376 11/18722 0.0196264204550755 0.0925211426562257 N4BP2L2/PIM1 2 GO:1905050 positive regulation of metallopeptidase activity 2/376 11/18722 0.0196264204550755 0.0925211426562257 MBP/STAT3 2 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 2/376 11/18722 0.0196264204550755 0.0925211426562257 MBP/TNF 2 GO:0048753 pigment granule organization 3/376 29/18722 0.0199518953470546 0.0937134478422259 RAB29/ZEB2/LYST 3 GO:0060969 negative regulation of gene silencing 3/376 29/18722 0.0199518953470546 0.0937134478422259 TNF/TGFB1/STAT3 3 GO:0062098 regulation of programmed necrotic cell death 3/376 29/18722 0.0199518953470546 0.0937134478422259 CASP8/CYLD/CFLAR 3 GO:0099024 plasma membrane invagination 7/376 136/18722 0.0200625129903599 0.0941102323637484 TRDC/RAC2/TRBC1/TRBC2/ITGB2/BIN2/CDC42 7 GO:0035821 modulation of process of other organism 6/376 106/18722 0.0200849450747922 0.0941102323637484 CCL4/CCL5/PRF1/CCL3/CFL1/JUN 6 GO:0035196 production of miRNAs involved in gene silencing by miRNA 4/376 52/18722 0.0203349125034287 0.0949747410082717 TNF/DDX5/TGFB1/STAT3 4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 5/376 78/18722 0.0203429767837072 0.0949747410082717 TNF/CDKN2D/CD44/CARD16/RPS6KA3 5 GO:0070373 negative regulation of ERK1 and ERK2 cascade 5/376 78/18722 0.0203429767837072 0.0949747410082717 PTPRC/TBC1D10C/DUSP1/CSK/SLC9A3R1 5 GO:0099173 postsynapse organization 8/376 168/18722 0.0204209187790369 0.0952238992403948 FYN/SRGN/CFL1/ACTB/ABHD17A/CDC42/ACTR2/ACTG1 8 GO:0000018 regulation of DNA recombination 6/376 107/18722 0.0209312508584347 0.0973692641974001 IL7R/PTPRC/TGFB1/WAS/TERF2IP/ACTR2 6 GO:0031532 actin cytoskeleton reorganization 6/376 107/18722 0.0209312508584347 0.0973692641974001 PLEK/ARHGDIB/GPR65/GMFG/FLNA/CDC42 6 GO:0048762 mesenchymal cell differentiation 10/376 236/18722 0.0213427558486331 0.0989867081835286 EOMES/S100A4/DDX5/TGFB1/FLNA/STAT1/SEMA4D/GLIPR2/DDX17/ROCK1 10 GO:0006446 regulation of translational initiation 5/376 79/18722 0.0213718751763725 0.0989867081835286 CCL5/TNF/EIF1/EIF4A2/PPP1R15A 5 GO:0051279 regulation of release of sequestered calcium ion into cytosol 5/376 79/18722 0.0213718751763725 0.0989867081835286 XCL1/CORO1A/CYBA/CALM1/PTPN6 5 GO:0045765 regulation of angiogenesis 13/376 342/18722 0.0213811289676422 0.0989867081835286 ETS1/KLF2/JAK1/TNF/BTG1/CXCR4/MTDH/TNFAIP3/STAT1/SP100/XBP1/STAT3/ROCK1 13 GO:0033059 cellular pigmentation 4/376 53/18722 0.0216567655606617 0.1000638629275 RAB29/RAB27A/ZEB2/LYST 4 GO:0007259 receptor signaling pathway via JAK-STAT 8/376 170/18722 0.0217443722381338 0.1000638629275 CCL5/PTPRC/FYN/JAK1/TNF/STAT1/IL10RA/STAT3 8 GO:0043487 regulation of RNA stability 8/376 170/18722 0.0217443722381338 0.1000638629275 ZFP36L2/VIM/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 8 GO:0017145 stem cell division 3/376 30/18722 0.0218462007836554 0.1000638629275 ZFP36L2/LBH/EVI2B 3 GO:0032480 negative regulation of type I interferon production 3/376 30/18722 0.0218462007836554 0.1000638629275 CYLD/REL/PYCARD 3 GO:0045948 positive regulation of translational initiation 3/376 30/18722 0.0218462007836554 0.1000638629275 CCL5/TNF/PPP1R15A 3 GO:0051125 regulation of actin nucleation 3/376 30/18722 0.0218462007836554 0.1000638629275 CORO1A/GMFG/WAS 3 GO:0070229 negative regulation of lymphocyte apoptotic process 3/376 30/18722 0.0218462007836554 0.1000638629275 CCL5/IL7R/TSC22D3 3 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 3/376 30/18722 0.0218462007836554 0.1000638629275 PIK3R1/XBP1/PPP1R15A 3 GO:0071229 cellular response to acid chemical 5/376 80/18722 0.0224340808178333 0.102514225435264 KLF2/FYN/CYBA/TNF/XBP1 5 GO:0120193 tight junction organization 5/376 80/18722 0.0224340808178333 0.102514225435264 TNF/MTDH/PRKCH/ACTG1/ROCK1 5 GO:0031050 dsRNA processing 4/376 54/18722 0.0230300100896394 0.103881832606628 TNF/DDX5/TGFB1/STAT3 4 GO:0070228 regulation of lymphocyte apoptotic process 4/376 54/18722 0.0230300100896394 0.103881832606628 CCL5/IL7R/TSC22D3/CD3G 4 GO:0070918 production of small RNA involved in gene silencing by RNA 4/376 54/18722 0.0230300100896394 0.103881832606628 TNF/DDX5/TGFB1/STAT3 4 GO:0006216 cytidine catabolic process 2/376 12/18722 0.0232427222890184 0.103881832606628 APOBEC3G/APOBEC3C 2 GO:0009972 cytidine deamination 2/376 12/18722 0.0232427222890184 0.103881832606628 APOBEC3G/APOBEC3C 2 GO:0016554 cytidine to uridine editing 2/376 12/18722 0.0232427222890184 0.103881832606628 APOBEC3G/APOBEC3C 2 GO:0031453 positive regulation of heterochromatin assembly 2/376 12/18722 0.0232427222890184 0.103881832606628 MPHOSPH8/ATF7IP 2 GO:0032823 regulation of natural killer cell differentiation 2/376 12/18722 0.0232427222890184 0.103881832606628 PRDM1/RASGRP1 2 GO:0035739 CD4-positive, alpha-beta T cell proliferation 2/376 12/18722 0.0232427222890184 0.103881832606628 XCL1/CD81 2 GO:0043383 negative T cell selection 2/376 12/18722 0.0232427222890184 0.103881832606628 PTPRC/CD3E 2 GO:0046087 cytidine metabolic process 2/376 12/18722 0.0232427222890184 0.103881832606628 APOBEC3G/APOBEC3C 2 GO:0060009 Sertoli cell development 2/376 12/18722 0.0232427222890184 0.103881832606628 FLNA/ATRX 2 GO:0060907 positive regulation of macrophage cytokine production 2/376 12/18722 0.0232427222890184 0.103881832606628 SPON2/LAPTM5 2 GO:0072683 T cell extravasation 2/376 12/18722 0.0232427222890184 0.103881832606628 ITGAL/CD99 2 GO:0098974 postsynaptic actin cytoskeleton organization 2/376 12/18722 0.0232427222890184 0.103881832606628 ACTB/ACTG1 2 GO:0120263 positive regulation of heterochromatin organization 2/376 12/18722 0.0232427222890184 0.103881832606628 MPHOSPH8/ATF7IP 2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 2/376 12/18722 0.0232427222890184 0.103881832606628 DDX5/TGFB1 2 GO:2000035 regulation of stem cell division 2/376 12/18722 0.0232427222890184 0.103881832606628 LBH/EVI2B 2 GO:2000561 regulation of CD4-positive, alpha-beta T cell proliferation 2/376 12/18722 0.0232427222890184 0.103881832606628 XCL1/CD81 2 GO:0001960 negative regulation of cytokine-mediated signaling pathway 5/376 81/18722 0.0235299401549911 0.104802894368495 CCL5/PTPRC/ISG15/CARD16/SAMHD1 5 GO:0051817 modulation of process of other organism involved in symbiotic interaction 5/376 81/18722 0.0235299401549911 0.104802894368495 CCL4/CCL5/CCL3/CFL1/JUN 5 GO:0071260 cellular response to mechanical stimulus 5/376 81/18722 0.0235299401549911 0.104802894368495 CYBA/IRF1/PTGER4/CNN2/CASP8 5 GO:0017038 protein import 9/376 206/18722 0.0237150527753758 0.105506118834192 TXNIP/TGFB1/FLNA/RAB8B/TOMM7/PIK3R1/CBLB/STAT3/NFKBIA 9 GO:0002323 natural killer cell activation involved in immune response 3/376 31/18722 0.0238353127008865 0.105798209296604 CORO1A/HLA-F/RAB27A 3 GO:0030212 hyaluronan metabolic process 3/376 31/18722 0.0238353127008865 0.105798209296604 TGFB1/CD44/PIM1 3 GO:0032355 response to estradiol 7/376 141/18722 0.0238948999857007 0.105941347190606 ETS1/TXNIP/TGFB1/CASP8/DUSP1/STAT3/CFLAR 7 GO:1901342 regulation of vasculature development 13/376 348/18722 0.0242168614311328 0.107246100623588 ETS1/KLF2/JAK1/TNF/BTG1/CXCR4/MTDH/TNFAIP3/STAT1/SP100/XBP1/STAT3/ROCK1 13 GO:0000768 syncytium formation by plasma membrane fusion 4/376 55/18722 0.0244550591646188 0.10793092740649 CD53/TYROBP/CD81/CFLAR 4 GO:0140253 cell-cell fusion 4/376 55/18722 0.0244550591646188 0.10793092740649 CD53/TYROBP/CD81/CFLAR 4 GO:1905517 macrophage migration 4/376 55/18722 0.0244550591646188 0.10793092740649 CCL5/CCL3/CKLF/CD81 4 GO:0001892 embryonic placenta development 5/376 82/18722 0.0246597840595248 0.108587117307566 EOMES/PRDM1/STK4/JUNB/CASP8 5 GO:0002312 B cell activation involved in immune response 5/376 82/18722 0.0246597840595248 0.108587117307566 PTPRC/ITM2A/TGFB1/LGALS1/XBP1 5 GO:0045860 positive regulation of protein kinase activity 14/376 386/18722 0.0247454194837029 0.108840522700736 CCL5/PTPRC/RASGRP1/CCND2/LAT/TNF/CALM1/LCP2/STK4/TGFB1/CSK/AKAP13/TAOK3/DAZAP2 14 GO:0009410 response to xenobiotic stimulus 16/376 462/18722 0.0250435555194281 0.110026958772998 B2M/TXNIP/RORA/FYN/LCK/CYBA/CXCR4/JUN/STAT1/FOS/LGALS1/RAP1B/STAT3/FOSB/GUK1/PPP1R12A 16 GO:0006401 RNA catabolic process 11/376 278/18722 0.0253817527221833 0.111386513928041 ZFP36L2/ISG20/VIM/DDX5/ATM/ZFP36/PABPC1/BTG2/CNOT6L/TNRC6B/ROCK1 11 GO:0006605 protein targeting 12/376 314/18722 0.0254635813401431 0.111619205535129 RAC2/FYN/ITGB2/RAB27A/RAB8B/LAPTM5/YWHAZ/TOMM7/SORL1/GNPTAB/VPS13C/GCC2 12 GO:0009141 nucleoside triphosphate metabolic process 6/376 112/18722 0.0255255579909503 0.111638303854325 TMSB4X/GIMAP7/TGFB1/SAMHD1/STAT3/GUK1 6 GO:0043406 positive regulation of MAP kinase activity 6/376 112/18722 0.0255255579909503 0.111638303854325 RASGRP1/TNF/TGFB1/CSK/AKAP13/TAOK3 6 GO:0043367 CD4-positive, alpha-beta T cell differentiation 5/376 83/18722 0.025823927684991 0.112402244364155 RUNX3/RORA/SPN/PTGER4/STAT3 5 GO:0007435 salivary gland morphogenesis 3/376 32/18722 0.0259191721927219 0.112402244364155 TNF/TGFB1/CDC42 3 GO:0032196 transposition 3/376 32/18722 0.0259191721927219 0.112402244364155 APOBEC3G/MYBL1/APOBEC3C 3 GO:0051497 negative regulation of stress fiber assembly 3/376 32/18722 0.0259191721927219 0.112402244364155 WAS/PFN1/PIK3R1 3 GO:0002886 regulation of myeloid leukocyte mediated immunity 4/376 56/18722 0.0259322855384656 0.112402244364155 RAC2/HLA-E/ITGB2/TYROBP 4 GO:0032608 interferon-beta production 4/376 56/18722 0.0259322855384656 0.112402244364155 IRF1/ISG15/REL/PYCARD 4 GO:0032648 regulation of interferon-beta production 4/376 56/18722 0.0259322855384656 0.112402244364155 IRF1/ISG15/REL/PYCARD 4 GO:0071385 cellular response to glucocorticoid stimulus 4/376 56/18722 0.0259322855384656 0.112402244364155 ZFP36L2/DDIT4/ZFP36/CFLAR 4 GO:0010324 membrane invagination 7/376 144/18722 0.0264213804193814 0.114266572684267 TRDC/RAC2/TRBC1/TRBC2/ITGB2/BIN2/CDC42 7 GO:0046718 viral entry into host cell 7/376 144/18722 0.0264213804193814 0.114266572684267 IFITM1/IFITM2/CXCR4/SELPLG/TRIM22/LGALS1/CD81 7 GO:0051656 establishment of organelle localization 14/376 390/18722 0.0267038899375633 0.115055934600746 RAC2/RASGRP1/LAT/ITGA4/CFL1/RAB27A/SUN2/YWHAZ/MYO1F/SLC9A3R1/ACTR3/CDC42/ACTR2/CENPC 14 GO:0031346 positive regulation of cell projection organization 13/376 353/18722 0.0267853201896021 0.115055934600746 RAC2/FYN/FLNA/PFN1/SEMA4D/RAB8B/PIK3R1/ACTR3/CDC42EP3/CDC42/MACF1/ACTR2/CFLAR 13 GO:0051480 regulation of cytosolic calcium ion concentration 13/376 353/18722 0.0267853201896021 0.115055934600746 PTPRC/CD52/XCL1/CORO1A/GPR65/FYN/LCK/CYBA/CALM1/CXCR4/PTGER4/CCL3/PTPN6 13 GO:0014842 regulation of skeletal muscle satellite cell proliferation 2/376 13/18722 0.0271089198747827 0.115055934600746 STAT3/CFLAR 2 GO:0031272 regulation of pseudopodium assembly 2/376 13/18722 0.0271089198747827 0.115055934600746 CDC42EP3/CDC42 2 GO:0031274 positive regulation of pseudopodium assembly 2/376 13/18722 0.0271089198747827 0.115055934600746 CDC42EP3/CDC42 2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway 2/376 13/18722 0.0271089198747827 0.115055934600746 TNFAIP3/CARD16 2 GO:0034135 regulation of toll-like receptor 2 signaling pathway 2/376 13/18722 0.0271089198747827 0.115055934600746 CYBA/TNFAIP3 2 GO:0035745 T-helper 2 cell cytokine production 2/376 13/18722 0.0271089198747827 0.115055934600746 XCL1/CD81 2 GO:0042492 gamma-delta T cell differentiation 2/376 13/18722 0.0271089198747827 0.115055934600746 PTPRC/KLRC1 2 GO:0046642 negative regulation of alpha-beta T cell proliferation 2/376 13/18722 0.0271089198747827 0.115055934600746 XCL1/CBLB 2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway 2/376 13/18722 0.0271089198747827 0.115055934600746 PTPN22/TNFAIP3 2 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response 2/376 13/18722 0.0271089198747827 0.115055934600746 PIK3R1/XBP1 2 GO:1903651 positive regulation of cytoplasmic transport 2/376 13/18722 0.0271089198747827 0.115055934600746 MSN/SORL1 2 GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 2/376 13/18722 0.0271089198747827 0.115055934600746 TOMM7/VPS13C 2 GO:1905269 positive regulation of chromatin organization 2/376 13/18722 0.0271089198747827 0.115055934600746 MPHOSPH8/ATF7IP 2 GO:2000551 regulation of T-helper 2 cell cytokine production 2/376 13/18722 0.0271089198747827 0.115055934600746 XCL1/CD81 2 GO:0010506 regulation of autophagy 12/376 317/18722 0.0271383546387308 0.115055934600746 PTPN22/PIP4K2A/IFI16/TRIM22/ATM/MTDH/IL10RA/VPS13C/PYCARD/STAT3/MCL1/ROCK1 12 GO:0040013 negative regulation of locomotion 14/376 391/18722 0.0272109439164378 0.115237604017701 IFITM1/ARHGDIB/EVL/TNF/PTGER4/BST2/TGFB1/CNN2/WAS/SEMA4D/SP100/DUSP1/SLC9A3R1/STAT3 14 GO:0051402 neuron apoptotic process 10/376 246/18722 0.0274143650260134 0.115972341130788 CORO1A/FYN/TNF/CCL3/TYROBP/NR4A2/JUN/BTG2/CDC42/MCL1 10 GO:0006949 syncytium formation 4/376 57/18722 0.0274620220181276 0.11604725771019 CD53/TYROBP/CD81/CFLAR 4 GO:1904892 regulation of receptor signaling pathway via STAT 6/376 114/18722 0.0275372150586322 0.116238244392374 CCL5/IL7R/PTPRC/TNF/TGFB1/IL10RA 6 GO:0002335 mature B cell differentiation 3/376 33/18722 0.0280975951247398 0.117579029274694 ITM2A/LGALS1/XBP1 3 GO:0032633 interleukin-4 production 3/376 33/18722 0.0280975951247398 0.117579029274694 CD3E/HLA-E/FCER1G 3 GO:0032673 regulation of interleukin-4 production 3/376 33/18722 0.0280975951247398 0.117579029274694 CD3E/HLA-E/FCER1G 3 GO:0034110 regulation of homotypic cell-cell adhesion 3/376 33/18722 0.0280975951247398 0.117579029274694 CCL5/JAK1/LGALS1 3 GO:0035025 positive regulation of Rho protein signal transduction 3/376 33/18722 0.0280975951247398 0.117579029274694 GPR65/ARHGEF3/AKAP13 3 GO:0036336 dendritic cell migration 3/376 33/18722 0.0280975951247398 0.117579029274694 CCL5/CXCR4/CDC42 3 GO:1901099 negative regulation of signal transduction in absence of ligand 3/376 33/18722 0.0280975951247398 0.117579029274694 FYN/TNF/MCL1 3 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 3/376 33/18722 0.0280975951247398 0.117579029274694 FYN/TNF/MCL1 3 GO:0007043 cell-cell junction assembly 7/376 146/18722 0.0282034042398752 0.11789448913648 TNF/MTDH/ACTB/TLN1/PRKCH/ACTG1/ROCK1 7 GO:0071277 cellular response to calcium ion 5/376 85/18722 0.0282562953953798 0.117988302432216 ALOX5AP/JUNB/FOS/JUND/FOSB 5 GO:0009895 negative regulation of catabolic process 12/376 320/18722 0.0288920049488833 0.120512937757721 FYN/PTPN22/TNF/DDIT4/FLNA/ZFP36/IL10RA/PABPC1/SORL1/STAT3/MCL1/ROCK1 12 GO:0032481 positive regulation of type I interferon production 4/376 58/18722 0.0290445618848617 0.120759310411844 PTPN22/IRF1/STAT1/ISG15 4 GO:0042743 hydrogen peroxide metabolic process 4/376 58/18722 0.0290445618848617 0.120759310411844 RAC2/FYN/CYBA/STAT3 4 GO:2000736 regulation of stem cell differentiation 4/376 58/18722 0.0290445618848617 0.120759310411844 ZFP36L2/LBH/N4BP2L2/STAT3 4 GO:0000082 G1/S transition of mitotic cell cycle 9/376 214/18722 0.0293408163787012 0.121860303823652 CCND2/ATM/CDKN2D/RBL2/PSME1/ID2/KMT2E/PTPN6/PRMT2 9 GO:0022406 membrane docking 5/376 86/18722 0.0295250701698143 0.122363258725166 PLEK/MSN/CALM1/RAB8B/ROCK1 5 GO:0060761 negative regulation of response to cytokine stimulus 5/376 86/18722 0.0295250701698143 0.122363258725166 CCL5/PTPRC/ISG15/CARD16/SAMHD1 5 GO:2000146 negative regulation of cell motility 13/376 359/18722 0.0301253255382965 0.124717560321473 IFITM1/ARHGDIB/EVL/TNF/PTGER4/BST2/TGFB1/CNN2/WAS/SP100/DUSP1/SLC9A3R1/STAT3 13 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 3/376 34/18722 0.0303702789286571 0.124798336000579 B2M/FCER1G/PYCARD 3 GO:0006356 regulation of transcription by RNA polymerase I 3/376 34/18722 0.0303702789286571 0.124798336000579 FLNA/LYAR/NCL 3 GO:0007431 salivary gland development 3/376 34/18722 0.0303702789286571 0.124798336000579 TNF/TGFB1/CDC42 3 GO:0035308 negative regulation of protein dephosphorylation 3/376 34/18722 0.0303702789286571 0.124798336000579 TNF/PPP1R15A/ROCK1 3 GO:0055094 response to lipoprotein particle 3/376 34/18722 0.0303702789286571 0.124798336000579 ITGB2/FCER1G/CD81 3 GO:0070232 regulation of T cell apoptotic process 3/376 34/18722 0.0303702789286571 0.124798336000579 CCL5/IL7R/TSC22D3 3 GO:0098751 bone cell development 3/376 34/18722 0.0303702789286571 0.124798336000579 PIP4K2A/TYROBP/PTPN6 3 GO:0043407 negative regulation of MAP kinase activity 4/376 59/18722 0.0306801593559811 0.125804886248071 PTPN22/DUSP1/SORL1/PTPN6 4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 4/376 59/18722 0.0306801593559811 0.125804886248071 PTPRC/SEMA4D/CBLB/PTPN6 4 GO:1900182 positive regulation of protein localization to nucleus 5/376 87/18722 0.0308292458852759 0.125992287958604 PYHIN1/FYN/TGFB1/FLNA/PIK3R1 5 GO:0032688 negative regulation of interferon-beta production 2/376 14/18722 0.0312135732749057 0.125992287958604 REL/PYCARD 2 GO:0034616 response to laminar fluid shear stress 2/376 14/18722 0.0312135732749057 0.125992287958604 ETS1/KLF2 2 GO:0045006 DNA deamination 2/376 14/18722 0.0312135732749057 0.125992287958604 APOBEC3G/APOBEC3C 2 GO:0045820 negative regulation of glycolytic process 2/376 14/18722 0.0312135732749057 0.125992287958604 DDIT4/STAT3 2 GO:0046131 pyrimidine ribonucleoside metabolic process 2/376 14/18722 0.0312135732749057 0.125992287958604 APOBEC3G/APOBEC3C 2 GO:0046133 pyrimidine ribonucleoside catabolic process 2/376 14/18722 0.0312135732749057 0.125992287958604 APOBEC3G/APOBEC3C 2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 2/376 14/18722 0.0312135732749057 0.125992287958604 FYN/CXCR4 2 GO:0051764 actin crosslink formation 2/376 14/18722 0.0312135732749057 0.125992287958604 LCP1/FLNA 2 GO:0071236 cellular response to antibiotic 2/376 14/18722 0.0312135732749057 0.125992287958604 CRIP1/ACTR2 2 GO:0071481 cellular response to X-ray 2/376 14/18722 0.0312135732749057 0.125992287958604 CCND2/ATM 2 GO:0090308 regulation of DNA methylation-dependent heterochromatin assembly 2/376 14/18722 0.0312135732749057 0.125992287958604 MPHOSPH8/ATF7IP 2 GO:0099188 postsynaptic cytoskeleton organization 2/376 14/18722 0.0312135732749057 0.125992287958604 ACTB/ACTG1 2 GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 2/376 14/18722 0.0312135732749057 0.125992287958604 TOMM7/VPS13C 2 GO:2001171 positive regulation of ATP biosynthetic process 2/376 14/18722 0.0312135732749057 0.125992287958604 TMSB4X/STAT3 2 GO:0010951 negative regulation of endopeptidase activity 10/376 252/18722 0.031600145481787 0.127419941458819 CST7/TNF/IFI16/BST2/CDKN2D/CD44/CARD16/SORL1/RPS6KA3/ROCK1 10 GO:0045446 endothelial cell differentiation 6/376 118/18722 0.0318686437150064 0.128369017043295 MSN/TNF/BTG1/CXCR4/RAP1B/ROCK1 6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 4/376 60/18722 0.0323690300850309 0.129710435966386 CELF2/DDX5/MBNL1/DDX17 4 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 4/376 60/18722 0.0323690300850309 0.129710435966386 PTPN22/TNFAIP3/CYLD/NFKBIA 4 GO:0006893 Golgi to plasma membrane transport 4/376 60/18722 0.0323690300850309 0.129710435966386 CSK/VAMP2/MACF1/VAMP5 4 GO:0019731 antibacterial humoral response 4/376 60/18722 0.0323690300850309 0.129710435966386 HLA-A/HLA-E/SPON2/RPL39 4 GO:0061951 establishment of protein localization to plasma membrane 4/376 60/18722 0.0323690300850309 0.129710435966386 CSK/VAMP2/MACF1/VAMP5 4 GO:0009119 ribonucleoside metabolic process 3/376 35/18722 0.0327368091411217 0.130643805789749 APOBEC3G/APOBEC3C/APRT 3 GO:0032232 negative regulation of actin filament bundle assembly 3/376 35/18722 0.0327368091411217 0.130643805789749 WAS/PFN1/PIK3R1 3 GO:0035633 maintenance of blood-brain barrier 3/376 35/18722 0.0327368091411217 0.130643805789749 MBP/ACTB/ACTG1 3 GO:0097421 liver regeneration 3/376 35/18722 0.0327368091411217 0.130643805789749 UCP2/RPL19/SRSF5 3 GO:0044409 entry into host 7/376 151/18722 0.0330103738809093 0.131599998753625 IFITM1/IFITM2/CXCR4/SELPLG/TRIM22/LGALS1/CD81 7 GO:2001020 regulation of response to DNA damage stimulus 9/376 219/18722 0.0332975958913361 0.132608616730655 PYHIN1/DDX5/ATM/CDKN2D/CD44/WAS/TERF2IP/ACTR2/MCL1 9 GO:0071384 cellular response to corticosteroid stimulus 4/376 61/18722 0.0341113516974447 0.135709946434906 ZFP36L2/DDIT4/ZFP36/CFLAR 4 GO:0071478 cellular response to radiation 8/376 186/18722 0.0345752112223611 0.137414301011948 CRIP1/CCND2/CYBA/IFI16/ATM/PIK3R1/EEF1D/CARD16 8 GO:0030901 midbrain development 5/376 90/18722 0.0349564482459403 0.138431353396812 MBP/CALM1/NR4A2/ACTB/CDC42 5 GO:0045638 negative regulation of myeloid cell differentiation 5/376 90/18722 0.0349564482459403 0.138431353396812 CCL3/ZFP36/PIK3R1/KLF13/NFKBIA 5 GO:0099175 regulation of postsynapse organization 5/376 90/18722 0.0349564482459403 0.138431353396812 FYN/SRGN/CFL1/ABHD17A/ACTR2 5 GO:0051271 negative regulation of cellular component movement 13/376 367/18722 0.0350370573843503 0.138431353396812 IFITM1/ARHGDIB/EVL/TNF/PTGER4/BST2/TGFB1/CNN2/WAS/SP100/DUSP1/SLC9A3R1/STAT3 13 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 3/376 36/18722 0.0351966656949207 0.138431353396812 B2M/FCER1G/PYCARD 3 GO:0002691 regulation of cellular extravasation 3/376 36/18722 0.0351966656949207 0.138431353396812 ITGA4/PTGER4/CD99 3 GO:0036314 response to sterol 3/376 36/18722 0.0351966656949207 0.138431353396812 RORA/CCL3/TGFB1 3 GO:0060338 regulation of type I interferon-mediated signaling pathway 3/376 36/18722 0.0351966656949207 0.138431353396812 ISG15/SAMHD1/PTPN6 3 GO:0071402 cellular response to lipoprotein particle stimulus 3/376 36/18722 0.0351966656949207 0.138431353396812 ITGB2/FCER1G/CD81 3 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 3/376 36/18722 0.0351966656949207 0.138431353396812 GZMB/RAC2/TOMM7 3 GO:0002224 toll-like receptor signaling pathway 6/376 121/18722 0.0353930695117063 0.138431353396812 PTPN22/CYBA/IRF1/TNFAIP3/RPS6KA3/NFKBIA 6 GO:1904019 epithelial cell apoptotic process 6/376 121/18722 0.0353930695117063 0.138431353396812 TNF/ITGA4/STK4/TNFAIP3/ZFP36/CFLAR 6 GO:0014841 skeletal muscle satellite cell proliferation 2/376 15/18722 0.0355455991302782 0.138431353396812 STAT3/CFLAR 2 GO:0014857 regulation of skeletal muscle cell proliferation 2/376 15/18722 0.0355455991302782 0.138431353396812 STAT3/CFLAR 2 GO:0031269 pseudopodium assembly 2/376 15/18722 0.0355455991302782 0.138431353396812 CDC42EP3/CDC42 2 GO:0032488 Cdc42 protein signal transduction 2/376 15/18722 0.0355455991302782 0.138431353396812 WAS/CDC42 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/376 15/18722 0.0355455991302782 0.138431353396812 TMSB4X/NFKBIA 2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum 2/376 15/18722 0.0355455991302782 0.138431353396812 SORL1/CD81 2 GO:0071380 cellular response to prostaglandin E stimulus 2/376 15/18722 0.0355455991302782 0.138431353396812 GNG2/PTGER4 2 GO:1905168 positive regulation of double-strand break repair via homologous recombination 2/376 15/18722 0.0355455991302782 0.138431353396812 WAS/ACTR2 2 GO:0002260 lymphocyte homeostasis 4/376 62/18722 0.0359072643588642 0.139001647742856 TSC22D3/CORO1A/LAT/TNFAIP3 4 GO:0032615 interleukin-12 production 4/376 62/18722 0.0359072643588642 0.139001647742856 HLA-B/LTB/IRF1/LAPTM5 4 GO:0032655 regulation of interleukin-12 production 4/376 62/18722 0.0359072643588642 0.139001647742856 HLA-B/LTB/IRF1/LAPTM5 4 GO:0032757 positive regulation of interleukin-8 production 4/376 62/18722 0.0359072643588642 0.139001647742856 CD2/TNF/PYCARD/STAT3 4 GO:0045576 mast cell activation 4/376 62/18722 0.0359072643588642 0.139001647742856 RAC2/RASGRP1/LAT/LCP2 4 GO:0070265 necrotic cell death 4/376 62/18722 0.0359072643588642 0.139001647742856 TNF/CASP8/CYLD/CFLAR 4 GO:0034655 nucleobase-containing compound catabolic process 14/376 407/18722 0.03632173974363 0.140465809886793 ZFP36L2/APOBEC3G/ISG20/VIM/APOBEC3C/DDX5/ATM/ZFP36/PABPC1/BTG2/SAMHD1/CNOT6L/TNRC6B/ROCK1 14 GO:0045582 positive regulation of T cell differentiation 5/376 91/18722 0.0364044162301741 0.140645177359845 IL7R/PTPRC/RUNX3/RASGRP1/XBP1 5 GO:0019730 antimicrobial humoral response 6/376 122/18722 0.0366213726407131 0.141342449186019 GNLY/HLA-A/HLA-E/SPON2/RPL39/RPL30 6 GO:0006606 protein import into nucleus 7/376 155/18722 0.0372281479897677 0.143398681372117 TXNIP/TGFB1/FLNA/PIK3R1/CBLB/STAT3/NFKBIA 7 GO:0007519 skeletal muscle tissue development 7/376 155/18722 0.0372281479897677 0.143398681372117 DDX5/TGFB1/FOS/BTG2/CFLAR/VAMP5/DDX17 7 GO:0003161 cardiac conduction system development 3/376 37/18722 0.0377492289705249 0.144401048628612 HOPX/ID2/CDC42 3 GO:0033120 positive regulation of RNA splicing 3/376 37/18722 0.0377492289705249 0.144401048628612 PIK3R1/NCL/SRSF5 3 GO:0043403 skeletal muscle tissue regeneration 3/376 37/18722 0.0377492289705249 0.144401048628612 HOPX/CD81/CFLAR 3 GO:0045616 regulation of keratinocyte differentiation 3/376 37/18722 0.0377492289705249 0.144401048628612 ZFP36/PRKCH/ROCK1 3 GO:0045730 respiratory burst 3/376 37/18722 0.0377492289705249 0.144401048628612 CD52/RAC2/CYBA 3 GO:0060416 response to growth hormone 3/376 37/18722 0.0377492289705249 0.144401048628612 PIK3R1/STAT3/LEPROTL1 3 GO:0071985 multivesicular body sorting pathway 3/376 37/18722 0.0377492289705249 0.144401048628612 RAB27A/LYST/LEPROTL1 3 GO:0010811 positive regulation of cell-substrate adhesion 6/376 123/18722 0.0378766891819773 0.144745730355189 CD3E/SKAP1/STK4/FLNA/CDC42/ROCK1 6 GO:0045862 positive regulation of proteolysis 13/376 372/18722 0.0383844227286136 0.146541515343229 PYHIN1/MBP/FYN/LCK/TNF/IFI16/CASP8/PSME1/LAPTM5/RNF19A/PYCARD/STAT3/CFLAR 13 GO:0010720 positive regulation of cell development 11/376 298/18722 0.0390577740240594 0.148818952156569 TNF/CXCR4/TYROBP/TGFB1/FLNA/ID2/SEMA4D/PRKCH/CDC42/MACF1/ACTR2 11 GO:0031647 regulation of protein stability 11/376 298/18722 0.0390577740240594 0.148818952156569 PYHIN1/STK4/TYROBP/FLNA/PFN1/TOMM7/PIK3R1/PIM1/PYCARD/CD81/ATF7IP 11 GO:0071241 cellular response to inorganic substance 9/376 226/18722 0.0394359283732447 0.149925196682906 B2M/ALOX5AP/JUNB/JUN/FOS/JUND/FOSB/CFLAR/ATRX 9 GO:0050821 protein stabilization 8/376 191/18722 0.039457098183418 0.149925196682906 PYHIN1/STK4/TYROBP/FLNA/PFN1/PIK3R1/PIM1/ATF7IP 8 GO:0007034 vacuolar transport 7/376 157/18722 0.0394641808042747 0.149925196682906 LAPTM5/LYST/SORL1/GNPTAB/VPS13C/LEPROTL1/GCC2 7 GO:0010466 negative regulation of peptidase activity 10/376 262/18722 0.0395441329689912 0.150081473888664 CST7/TNF/IFI16/BST2/CDKN2D/CD44/CARD16/SORL1/RPS6KA3/ROCK1 10 GO:0001885 endothelial cell development 4/376 64/18722 0.0396602398095462 0.150081473888664 MSN/TNF/RAP1B/ROCK1 4 GO:0046579 positive regulation of Ras protein signal transduction 4/376 64/18722 0.0396602398095462 0.150081473888664 GPR65/RASGRP1/ARHGEF3/AKAP13 4 GO:0048857 neural nucleus development 4/376 64/18722 0.0396602398095462 0.150081473888664 MBP/CALM1/ACTB/CDC42 4 GO:1901990 regulation of mitotic cell cycle phase transition 11/376 299/18722 0.0398542102093515 0.150111363700833 ZFP36L2/CCND2/ATM/RBL2/PSME1/ID2/DUSP1/KMT2E/PTPN6/TAOK3/PRMT2 11 GO:0002830 positive regulation of type 2 immune response 2/376 16/18722 0.040094261014287 0.150111363700833 XCL1/CD81 2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 2/376 16/18722 0.040094261014287 0.150111363700833 PYHIN1/SP100 2 GO:0030033 microvillus assembly 2/376 16/18722 0.040094261014287 0.150111363700833 FXYD5/SLC9A3R1 2 GO:0030575 nuclear body organization 2/376 16/18722 0.040094261014287 0.150111363700833 ETS1/SF1 2 GO:0031268 pseudopodium organization 2/376 16/18722 0.040094261014287 0.150111363700833 CDC42EP3/CDC42 2 GO:0034138 toll-like receptor 3 signaling pathway 2/376 16/18722 0.040094261014287 0.150111363700833 PTPN22/TNFAIP3 2 GO:0045779 negative regulation of bone resorption 2/376 16/18722 0.040094261014287 0.150111363700833 TNFAIP3/CSK 2 GO:0046135 pyrimidine nucleoside catabolic process 2/376 16/18722 0.040094261014287 0.150111363700833 APOBEC3G/APOBEC3C 2 GO:0097284 hepatocyte apoptotic process 2/376 16/18722 0.040094261014287 0.150111363700833 STK4/CFLAR 2 GO:0099010 modification of postsynaptic structure 2/376 16/18722 0.040094261014287 0.150111363700833 PFN1/CDC42 2 GO:0046329 negative regulation of JNK cascade 3/376 38/18722 0.0403937856156657 0.150795683295476 PTPN22/CYLD/TAOK3 3 GO:0048246 macrophage chemotaxis 3/376 38/18722 0.0403937856156657 0.150795683295476 CCL5/CCL3/CKLF 3 GO:0097242 amyloid-beta clearance 3/376 38/18722 0.0403937856156657 0.150795683295476 TNF/ITGB2/ROCK1 3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 5/376 94/18722 0.0409674046876445 0.152349993440137 CCND2/CDKN2D/TNFAIP3/ACTB/CCNL1 5 GO:0001738 morphogenesis of a polarized epithelium 5/376 94/18722 0.0409674046876445 0.152349993440137 MSN/ACTB/SLC9A3R1/CDC42/ACTG1 5 GO:0051702 biological process involved in interaction with symbiont 5/376 94/18722 0.0409674046876445 0.152349993440137 CCL4/CCL5/CCL3/CFL1/JUN 5 GO:1902414 protein localization to cell junction 5/376 94/18722 0.0409674046876445 0.152349993440137 JAK1/FLNA/ACTB/VAMP2/ACTG1 5 GO:0007565 female pregnancy 8/376 193/18722 0.0415324916517876 0.154303360643027 ETS1/ARHGDIB/PRDM1/JUNB/FOS/UCP2/LNPEP/FOSB 8 GO:0051170 import into nucleus 7/376 159/18722 0.041786303715169 0.155022797781609 TXNIP/TGFB1/FLNA/PIK3R1/CBLB/STAT3/NFKBIA 7 GO:0032874 positive regulation of stress-activated MAPK cascade 6/376 126/18722 0.0418061480469114 0.155022797781609 RASGRP1/TNF/TAOK3/PYCARD/CDC42/GADD45B 6 GO:0009314 response to radiation 15/376 456/18722 0.0430347572661186 0.159426084518365 PTPRC/CRIP1/CCND2/CYBA/IFI16/ATM/CDKN2D/JUN/FOS/ID2/JUND/DUSP1/PIK3R1/EEF1D/CARD16 15 GO:2000249 regulation of actin cytoskeleton reorganization 3/376 39/18722 0.0431295341404114 0.159624589106107 ARHGDIB/GMFG/CDC42 3 GO:0051346 negative regulation of hydrolase activity 13/376 379/18722 0.0434440439438601 0.160635181567231 GZMA/CST7/TNF/IFI16/BST2/CDKN2D/CD44/SEMA4D/CARD16/SORL1/RPS6KA3/PPP1R15A/ROCK1 13 GO:0042093 T-helper cell differentiation 4/376 66/18722 0.0436283519678131 0.161162882626573 RORA/SPN/PTGER4/STAT3 4 GO:1904035 regulation of epithelial cell apoptotic process 5/376 96/18722 0.044193305810429 0.16257296081586 TNF/ITGA4/TNFAIP3/ZFP36/CFLAR 5 GO:0045732 positive regulation of protein catabolic process 9/376 231/18722 0.0442639953713877 0.16257296081586 PYHIN1/MSN/TNF/TNFAIP3/LAPTM5/CBLB/SORL1/RNF19A/CD81 9 GO:0001952 regulation of cell-matrix adhesion 6/376 128/18722 0.044563325119991 0.16257296081586 CD3E/SKAP1/PIK3R1/MACF1/ACTG1/ROCK1 6 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 6/376 128/18722 0.044563325119991 0.16257296081586 RASGRP1/TNF/TAOK3/PYCARD/CDC42/GADD45B 6 GO:0001829 trophectodermal cell differentiation 2/376 17/18722 0.0448491600289431 0.16257296081586 HOPX/JUNB 2 GO:0009151 purine deoxyribonucleotide metabolic process 2/376 17/18722 0.0448491600289431 0.16257296081586 SAMHD1/GUK1 2 GO:0009200 deoxyribonucleoside triphosphate metabolic process 2/376 17/18722 0.0448491600289431 0.16257296081586 SAMHD1/GUK1 2 GO:0010715 regulation of extracellular matrix disassembly 2/376 17/18722 0.0448491600289431 0.16257296081586 ETS1/TGFB1 2 GO:0014856 skeletal muscle cell proliferation 2/376 17/18722 0.0448491600289431 0.16257296081586 STAT3/CFLAR 2 GO:0016045 detection of bacterium 2/376 17/18722 0.0448491600289431 0.16257296081586 HLA-A/HLA-B 2 GO:0031445 regulation of heterochromatin assembly 2/376 17/18722 0.0448491600289431 0.16257296081586 MPHOSPH8/ATF7IP 2 GO:0035855 megakaryocyte development 2/376 17/18722 0.0448491600289431 0.16257296081586 PIP4K2A/PTPN6 2 GO:0042053 regulation of dopamine metabolic process 2/376 17/18722 0.0448491600289431 0.16257296081586 ITGB2/NR4A2 2 GO:0042069 regulation of catecholamine metabolic process 2/376 17/18722 0.0448491600289431 0.16257296081586 ITGB2/NR4A2 2 GO:0042772 DNA damage response, signal transduction resulting in transcription 2/376 17/18722 0.0448491600289431 0.16257296081586 PYHIN1/SP100 2 GO:0060644 mammary gland epithelial cell differentiation 2/376 17/18722 0.0448491600289431 0.16257296081586 LBH/ID2 2 GO:0061158 3'-UTR-mediated mRNA destabilization 2/376 17/18722 0.0448491600289431 0.16257296081586 ZFP36L2/ZFP36 2 GO:0120261 regulation of heterochromatin organization 2/376 17/18722 0.0448491600289431 0.16257296081586 MPHOSPH8/ATF7IP 2 GO:1901550 regulation of endothelial cell development 2/376 17/18722 0.0448491600289431 0.16257296081586 TNF/ROCK1 2 GO:1903140 regulation of establishment of endothelial barrier 2/376 17/18722 0.0448491600289431 0.16257296081586 TNF/ROCK1 2 GO:0050678 regulation of epithelial cell proliferation 13/376 381/18722 0.0449717011031964 0.16286480539709 B2M/RUNX3/CYBA/TNF/ITGA4/TGFB1/TNFAIP3/ZFP36/STAT1/XBP1/STAT3/CDC42/CFLAR 13 GO:0051494 negative regulation of cytoskeleton organization 7/376 162/18722 0.0454328435186634 0.164381203207116 TMSB4X/CORO1A/GMFG/WAS/TMSB10/PFN1/PIK3R1 7 GO:0035914 skeletal muscle cell differentiation 4/376 67/18722 0.0456930546151676 0.164987145775519 DDX5/FOS/BTG2/DDX17 4 GO:0042130 negative regulation of T cell proliferation 4/376 67/18722 0.0456930546151676 0.164987145775519 XCL1/SPN/CBLB/PTPN6 4 GO:0070167 regulation of biomineral tissue development 5/376 97/18722 0.0458617462111113 0.164987145775519 SRGN/CCL3/TGFB1/ISG15/ROCK1 5 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 5/376 97/18722 0.0458617462111113 0.164987145775519 FYN/TNF/TNFAIP3/CFLAR/MCL1 5 GO:0010543 regulation of platelet activation 3/376 40/18722 0.0459555902949957 0.164987145775519 PLEK/TXK/FCER1G 3 GO:0045740 positive regulation of DNA replication 3/376 40/18722 0.0459555902949957 0.164987145775519 JUN/CDC42/ATRX 3 GO:1901223 negative regulation of NIK/NF-kappaB signaling 3/376 40/18722 0.0459555902949957 0.164987145775519 TMSB4X/LITAF/CYLD 3 GO:0030336 negative regulation of cell migration 12/376 344/18722 0.0459709234531759 0.164987145775519 IFITM1/ARHGDIB/EVL/TNF/PTGER4/BST2/TGFB1/CNN2/SP100/DUSP1/SLC9A3R1/STAT3 12 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 6/376 129/18722 0.045983514177435 0.164987145775519 LCK/TNF/CASP8/LAPTM5/PYCARD/CFLAR 6 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 9/376 233/18722 0.0463014293417119 0.165974133856738 GPR65/GNG2/ADGRE5/PTGER4/PRKACB/RGS1/FLNA/SLC9A3R1/AKAP13 9 GO:0001666 response to hypoxia 11/376 307/18722 0.0466352506156378 0.167016262602215 ETS1/MALAT1/RORA/CYBA/CXCR4/DDIT4/NR4A2/UCP2/CARD16/CFLAR/HP1BP3 11 GO:1904029 regulation of cyclin-dependent protein kinase activity 5/376 98/18722 0.0475672836141181 0.170039874543088 CCND2/CDKN2D/TNFAIP3/ACTB/CCNL1 5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 5/376 98/18722 0.0475672836141181 0.170039874543088 CDKN2D/CD44/XBP1/IVNS1ABP/MCL1 5 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 4/376 68/18722 0.0478114379403536 0.170597902411483 RORA/SPN/PTGER4/STAT3 4 GO:0034394 protein localization to cell surface 4/376 68/18722 0.0478114379403536 0.170597902411483 CD247/TNF/TYROBP/FLNA 4 GO:0010639 negative regulation of organelle organization 12/376 347/18722 0.048510889862986 0.172934404985346 TMSB4X/CORO1A/GMFG/ATM/WAS/TMSB10/PFN1/DUSP1/PIK3R1/TERF2IP/ODF2L/ATRX 12 GO:0032735 positive regulation of interleukin-12 production 3/376 41/18722 0.0488709922374387 0.173391440441022 LTB/IRF1/LAPTM5 3 GO:0042307 positive regulation of protein import into nucleus 3/376 41/18722 0.0488709922374387 0.173391440441022 TGFB1/FLNA/PIK3R1 3 GO:1902622 regulation of neutrophil migration 3/376 41/18722 0.0488709922374387 0.173391440441022 RAC2/XCL1/CD99 3 GO:1905521 regulation of macrophage migration 3/376 41/18722 0.0488709922374387 0.173391440441022 CCL5/CCL3/CD81 3 GO:2000008 regulation of protein localization to cell surface 3/376 41/18722 0.0488709922374387 0.173391440441022 CD247/TNF/TYROBP 3 GO:0046683 response to organophosphorus 6/376 131/18722 0.0489075727489129 0.173391440441022 JUN/STAT1/FOS/DUSP1/RAP1B/FOSB 6 GO:0110149 regulation of biomineralization 5/376 99/18722 0.0493099761095451 0.174480899045357 SRGN/CCL3/TGFB1/ISG15/ROCK1 5 GO:0002295 T-helper cell lineage commitment 2/376 18/18722 0.0498002256372039 0.174480899045357 SPN/STAT3 2 GO:0030889 negative regulation of B cell proliferation 2/376 18/18722 0.0498002256372039 0.174480899045357 TYROBP/ATM 2 GO:0034134 toll-like receptor 2 signaling pathway 2/376 18/18722 0.0498002256372039 0.174480899045357 CYBA/TNFAIP3 2 GO:0035743 CD4-positive, alpha-beta T cell cytokine production 2/376 18/18722 0.0498002256372039 0.174480899045357 XCL1/CD81 2 GO:0046851 negative regulation of bone remodeling 2/376 18/18722 0.0498002256372039 0.174480899045357 TNFAIP3/CSK 2 GO:0051447 negative regulation of meiotic cell cycle 2/376 18/18722 0.0498002256372039 0.174480899045357 PRKACB/DUSP1 2 GO:0060008 Sertoli cell differentiation 2/376 18/18722 0.0498002256372039 0.174480899045357 FLNA/ATRX 2 GO:0080182 histone H3-K4 trimethylation 2/376 18/18722 0.0498002256372039 0.174480899045357 KMT2A/KMT2E 2 GO:0097709 connective tissue replacement 2/376 18/18722 0.0498002256372039 0.174480899045357 TGFB1/ROCK1 2 GO:0150078 positive regulation of neuroinflammatory response 2/376 18/18722 0.0498002256372039 0.174480899045357 TNF/CCL3 2 GO:0150079 negative regulation of neuroinflammatory response 2/376 18/18722 0.0498002256372039 0.174480899045357 CST7/PTPRC 2 GO:1900242 regulation of synaptic vesicle endocytosis 2/376 18/18722 0.0498002256372039 0.174480899045357 CALM1/ROCK1 2 GO:0031060 regulation of histone methylation 4/376 69/18722 0.0499833980138139 0.174806558938203 KMT2A/KMT2E/MLLT6/ATRX 4 GO:1904377 positive regulation of protein localization to cell periphery 4/376 69/18722 0.0499833980138139 0.174806558938203 TNF/EPB41/PIK3R1/PRKCH 4 GO:0045667 regulation of osteoblast differentiation 6/376 132/18722 0.050411608195867 0.176145159385919 IFITM1/TNF/DDX5/SEMA4D/JUND/CLIC1 6 GO:0043112 receptor metabolic process 7/376 166/18722 0.0506038859025245 0.176339980100973 ITGB2/TGFB1/FCER1G/RAB29/LAPTM5/SORL1/CD81 7 GO:0060538 skeletal muscle organ development 7/376 166/18722 0.0506038859025245 0.176339980100973 DDX5/TGFB1/FOS/BTG2/CFLAR/VAMP5/DDX17 7 GO:1902904 negative regulation of supramolecular fiber organization 7/376 166/18722 0.0506038859025245 0.176339980100973 TMSB4X/CORO1A/GMFG/WAS/TMSB10/PFN1/PIK3R1 7 GO:0019932 second-messenger-mediated signaling 11/376 312/18722 0.0512519092338658 0.178437689381159 CCL4/PTPRC/CD3E/PLEK/TBC1D10C/LAT/TNF/CALM1/CXCR4/CCL3/SLC9A3R1 11 GO:0017157 regulation of exocytosis 8/376 202/18722 0.0517637457329587 0.179157293942921 RAC2/HLA-F/CALM1/ITGB2/RAB27A/RAB8B/VAMP2/RAP1B 8 GO:0007212 dopamine receptor signaling pathway 3/376 42/18722 0.0518747054977953 0.179157293942921 GNG2/FLNA/SLC9A3R1 3 GO:0007520 myoblast fusion 3/376 42/18722 0.0518747054977953 0.179157293942921 CD53/CD81/CFLAR 3 GO:0010677 negative regulation of cellular carbohydrate metabolic process 3/376 42/18722 0.0518747054977953 0.179157293942921 PLEK/DDIT4/STAT3 3 GO:0010939 regulation of necrotic cell death 3/376 42/18722 0.0518747054977953 0.179157293942921 CASP8/CYLD/CFLAR 3 GO:0032689 negative regulation of interferon-gamma production 3/376 42/18722 0.0518747054977953 0.179157293942921 XCL1/CD96/LAPTM5 3 GO:0033574 response to testosterone 3/376 42/18722 0.0518747054977953 0.179157293942921 MSN/DUSP1/CFLAR 3 GO:0045687 positive regulation of glial cell differentiation 3/376 42/18722 0.0518747054977953 0.179157293942921 CXCR4/TGFB1/ID2 3 GO:0072595 maintenance of protein localization in organelle 3/376 42/18722 0.0518747054977953 0.179157293942921 SYNE1/SP100/SUN2 3 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 4/376 70/18722 0.0522087988715053 0.179990298600608 PTPRC/B2M/XCL1/TGFB1 4 GO:0070830 bicellular tight junction assembly 4/376 70/18722 0.0522087988715053 0.179990298600608 TNF/MTDH/PRKCH/ROCK1 4 GO:0042176 regulation of protein catabolic process 13/376 391/18722 0.0531740373474383 0.183155017530065 PYHIN1/FYN/MSN/TNF/TNFAIP3/FLNA/PSME1/LAPTM5/CBLB/SORL1/RNF19A/CD81/ROCK1 13 GO:0018105 peptidyl-serine phosphorylation 11/376 315/18722 0.0541650323836993 0.186344538507834 TNF/DDIT4/STK4/TGFB1/ATM/CD44/PRKCH/TERF2IP/RPS6KA3/CLK1/ROCK1 11 GO:0071383 cellular response to steroid hormone stimulus 8/376 204/18722 0.0542393384956659 0.186344538507834 ZFP36L2/DDIT4/DDX5/LBH/ZFP36/PRMT2/CFLAR/DDX17 8 GO:0071230 cellular response to amino acid stimulus 4/376 71/18722 0.0544874732703948 0.186344538507834 FYN/CYBA/TNF/XBP1 4 GO:0150116 regulation of cell-substrate junction organization 4/376 71/18722 0.0544874732703948 0.186344538507834 PIK3R1/MACF1/ACTG1/ROCK1 4 GO:1902106 negative regulation of leukocyte differentiation 5/376 102/18722 0.0547613308814162 0.186344538507834 RUNX3/IRF1/CCL3/ID2/PIK3R1 5 GO:0002396 MHC protein complex assembly 2/376 19/18722 0.054937706725834 0.186344538507834 B2M/TAPBP 2 GO:0006491 N-glycan processing 2/376 19/18722 0.054937706725834 0.186344538507834 MGAT4A/GNPTAB 2 GO:0008356 asymmetric cell division 2/376 19/18722 0.054937706725834 0.186344538507834 ACTR3/ACTR2 2 GO:0043031 negative regulation of macrophage activation 2/376 19/18722 0.054937706725834 0.186344538507834 CST7/PTPRC 2 GO:0051571 positive regulation of histone H3-K4 methylation 2/376 19/18722 0.054937706725834 0.186344538507834 KMT2A/KMT2E 2 GO:0070262 peptidyl-serine dephosphorylation 2/376 19/18722 0.054937706725834 0.186344538507834 DUSP1/PPP1R15A 2 GO:0098780 response to mitochondrial depolarisation 2/376 19/18722 0.054937706725834 0.186344538507834 TOMM7/VPS13C 2 GO:1900221 regulation of amyloid-beta clearance 2/376 19/18722 0.054937706725834 0.186344538507834 TNF/ROCK1 2 GO:1901739 regulation of myoblast fusion 2/376 19/18722 0.054937706725834 0.186344538507834 CD53/CFLAR 2 GO:0034142 toll-like receptor 4 signaling pathway 3/376 43/18722 0.0549656277456656 0.186344538507834 PTPN22/TNFAIP3/NFKBIA 3 GO:0046636 negative regulation of alpha-beta T cell activation 3/376 43/18722 0.0549656277456656 0.186344538507834 XCL1/RUNX3/CBLB 3 GO:1904591 positive regulation of protein import 3/376 43/18722 0.0549656277456656 0.186344538507834 TGFB1/FLNA/PIK3R1 3 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 3/376 43/18722 0.0549656277456656 0.186344538507834 FYN/TNF/MCL1 3 GO:0044843 cell cycle G1/S phase transition 9/376 241/18722 0.0550722243706311 0.186542718038632 CCND2/ATM/CDKN2D/RBL2/PSME1/ID2/KMT2E/PTPN6/PRMT2 9 GO:0060348 bone development 8/376 205/18722 0.0555050797894149 0.18784470234409 PTPRC/PIP4K2A/PTGER4/TYROBP/SEMA4D/RPL13/AKAP13/PTPN6 8 GO:0014013 regulation of gliogenesis 5/376 103/18722 0.0566529133300726 0.19029774493308 TNF/CXCR4/TGFB1/ID2/PRKCH 5 GO:0003158 endothelium development 6/376 136/18722 0.0567093249880409 0.19029774493308 MSN/TNF/BTG1/CXCR4/RAP1B/ROCK1 6 GO:0045727 positive regulation of translation 6/376 136/18722 0.0567093249880409 0.19029774493308 CCL5/TNF/VIM/RPS4X/PABPC1/PPP1R15A 6 GO:0098876 vesicle-mediated transport to the plasma membrane 6/376 136/18722 0.0567093249880409 0.19029774493308 ARL4C/CSK/VAMP2/SORL1/MACF1/VAMP5 6 GO:1900180 regulation of protein localization to nucleus 6/376 136/18722 0.0567093249880409 0.19029774493308 PYHIN1/FYN/RASSF5/TGFB1/FLNA/PIK3R1 6 GO:1903305 regulation of regulated secretory pathway 6/376 136/18722 0.0567093249880409 0.19029774493308 RAC2/HLA-F/CALM1/ITGB2/RAB27A/RAP1B 6 GO:0042246 tissue regeneration 4/376 72/18722 0.0568192234548577 0.19029774493308 HOPX/TXK/CD81/CFLAR 4 GO:0042273 ribosomal large subunit biogenesis 4/376 72/18722 0.0568192234548577 0.19029774493308 RPL10/GTF3A/RPL35A/RPL3 4 GO:0043903 regulation of biological process involved in symbiotic interaction 4/376 72/18722 0.0568192234548577 0.19029774493308 IFITM1/IFITM2/TRIM22/LGALS1 4 GO:0051057 positive regulation of small GTPase mediated signal transduction 4/376 72/18722 0.0568192234548577 0.19029774493308 GPR65/RASGRP1/ARHGEF3/AKAP13 4 GO:0070227 lymphocyte apoptotic process 4/376 72/18722 0.0568192234548577 0.19029774493308 CCL5/IL7R/TSC22D3/CD3G 4 GO:1903036 positive regulation of response to wounding 4/376 72/18722 0.0568192234548577 0.19029774493308 CXCR4/FLNA/XBP1/ACTG1 4 GO:0030521 androgen receptor signaling pathway 3/376 44/18722 0.0581425933674073 0.19422633560233 DDX5/PRMT2/DDX17 3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 3/376 44/18722 0.0581425933674073 0.19422633560233 MSN/SLC9A3R1/CDC42 3 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 3/376 44/18722 0.0581425933674073 0.19422633560233 CCL5/TNF/IL10RA 3 GO:0010977 negative regulation of neuron projection development 6/376 137/18722 0.0583543906592794 0.19476594642955 B2M/VIM/FLNA/RAB29/SEMA4D/LGALS1 6 GO:0045621 positive regulation of lymphocyte differentiation 5/376 104/18722 0.0585817090166105 0.195356387641451 IL7R/PTPRC/RUNX3/RASGRP1/XBP1 5 GO:0050673 epithelial cell proliferation 14/376 437/18722 0.0589721820244463 0.196353068054171 B2M/RUNX3/CYBA/TNF/ITGA4/TGFB1/TNFAIP3/ZFP36/STAT1/ID2/XBP1/STAT3/CDC42/CFLAR 14 GO:0002221 pattern recognition receptor signaling pathway 7/376 172/18722 0.0590325998149959 0.196353068054171 PTPN22/CYBA/IRF1/TNFAIP3/CYLD/RPS6KA3/NFKBIA 7 GO:0042770 signal transduction in response to DNA damage 7/376 172/18722 0.0590325998149959 0.196353068054171 PYHIN1/DDX5/ATM/CD44/SP100/TAOK3/ATRX 7 GO:1901215 negative regulation of neuron death 8/376 208/18722 0.0594147308449639 0.197454615801231 CORO1A/HLA-F/FYN/NR4A2/REL/BTG2/SORL1/STAT3 8 GO:0051052 regulation of DNA metabolic process 12/376 359/18722 0.0596296417860752 0.197861975602944 GZMA/IL7R/PTPRC/TGFB1/ATM/WAS/KMT2A/DUSP1/TERF2IP/ACTR2/MPHOSPH8/ATRX 12 GO:0002577 regulation of antigen processing and presentation 2/376 20/18722 0.0602521628932835 0.197861975602944 WAS/PYCARD 2 GO:0006346 DNA methylation-dependent heterochromatin assembly 2/376 20/18722 0.0602521628932835 0.197861975602944 MPHOSPH8/ATF7IP 2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 2/376 20/18722 0.0602521628932835 0.197861975602944 CALM1/DDIT4 2 GO:0016553 base conversion or substitution editing 2/376 20/18722 0.0602521628932835 0.197861975602944 APOBEC3G/APOBEC3C 2 GO:0034104 negative regulation of tissue remodeling 2/376 20/18722 0.0602521628932835 0.197861975602944 TNFAIP3/CSK 2 GO:0043555 regulation of translation in response to stress 2/376 20/18722 0.0602521628932835 0.197861975602944 RPS6KA3/PPP1R15A 2 GO:0046629 gamma-delta T cell activation 2/376 20/18722 0.0602521628932835 0.197861975602944 PTPRC/KLRC1 2 GO:0060252 positive regulation of glial cell proliferation 2/376 20/18722 0.0602521628932835 0.197861975602944 TNF/PRKCH 2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway 2/376 20/18722 0.0602521628932835 0.197861975602944 ISG15/SAMHD1 2 GO:0071379 cellular response to prostaglandin stimulus 2/376 20/18722 0.0602521628932835 0.197861975602944 GNG2/PTGER4 2 GO:0072567 chemokine (C-X-C motif) ligand 2 production 2/376 20/18722 0.0602521628932835 0.197861975602944 MBP/TNF 2 GO:0098543 detection of other organism 2/376 20/18722 0.0602521628932835 0.197861975602944 HLA-A/HLA-B 2 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 2/376 20/18722 0.0602521628932835 0.197861975602944 MBP/TNF 2 GO:2001022 positive regulation of response to DNA damage stimulus 5/376 105/18722 0.0605476841099583 0.198664077837501 PYHIN1/DDX5/ATM/WAS/ACTR2 5 GO:0031668 cellular response to extracellular stimulus 9/376 246/18722 0.0610681725704073 0.200202342394525 PTPRC/ITGA4/IFI16/NR4A2/JUN/FOS/UCP2/XBP1/PIM1 9 GO:0036293 response to decreased oxygen levels 11/376 322/18722 0.0613876966629812 0.200456583154838 ETS1/MALAT1/RORA/CYBA/CXCR4/DDIT4/NR4A2/UCP2/CARD16/CFLAR/HP1BP3 11 GO:0002920 regulation of humoral immune response 3/376 45/18722 0.0614043778593014 0.200456583154838 PTPRC/TNF/PTPN6 3 GO:0035272 exocrine system development 3/376 45/18722 0.0614043778593014 0.200456583154838 TNF/TGFB1/CDC42 3 GO:0035987 endodermal cell differentiation 3/376 45/18722 0.0614043778593014 0.200456583154838 EOMES/ITGB2/ITGA4 3 GO:0071354 cellular response to interleukin-6 3/376 45/18722 0.0614043778593014 0.200456583154838 JAK1/SELPLG/STAT3 3 GO:0006801 superoxide metabolic process 4/376 74/18722 0.0616410122567857 0.200721783609281 CYBA/ITGB2/TYROBP/TGFB1 4 GO:0007040 lysosome organization 4/376 74/18722 0.0616410122567857 0.200721783609281 CORO1A/LAPTM5/LYST/GNPTAB 4 GO:0080171 lytic vacuole organization 4/376 74/18722 0.0616410122567857 0.200721783609281 CORO1A/LAPTM5/LYST/GNPTAB 4 GO:0031396 regulation of protein ubiquitination 8/376 210/18722 0.0621153229622714 0.20209645380252 FYN/PTPN22/RASSF5/TNFAIP3/LAPTM5/ISG15/CBLB/IVNS1ABP 8 GO:0001824 blastocyst development 5/376 106/18722 0.0625507900027883 0.202832059632472 HOPX/JUNB/N4BP2L2/RPL13/CMTM3 5 GO:0006906 vesicle fusion 5/376 106/18722 0.0625507900027883 0.202832059632472 CORO1A/PIP4K2A/SAMD9/RAB8B/VAMP2 5 GO:0046822 regulation of nucleocytoplasmic transport 5/376 106/18722 0.0625507900027883 0.202832059632472 TGFB1/FLNA/SP100/PIK3R1/PPP1R12A 5 GO:1903707 negative regulation of hemopoiesis 5/376 106/18722 0.0625507900027883 0.202832059632472 RUNX3/IRF1/CCL3/ID2/PIK3R1 5 GO:0031333 negative regulation of protein-containing complex assembly 6/376 140/18722 0.0634595839017905 0.205606929447691 TMSB4X/PTGER4/TMSB10/PFN1/SORL1/CDC42 6 GO:0052126 movement in host environment 7/376 175/18722 0.0635527044099057 0.205736616197481 IFITM1/IFITM2/CXCR4/SELPLG/TRIM22/LGALS1/CD81 7 GO:0034121 regulation of toll-like receptor signaling pathway 4/376 75/18722 0.0641305098182356 0.207433827667498 PTPN22/CYBA/IRF1/TNFAIP3 4 GO:0006383 transcription by RNA polymerase III 3/376 46/18722 0.0647497020427373 0.208739680046262 POLR3GL/GTF3A/IVNS1ABP 3 GO:0043300 regulation of leukocyte degranulation 3/376 46/18722 0.0647497020427373 0.208739680046262 RAC2/HLA-F/ITGB2 3 GO:0070828 heterochromatin organization 3/376 46/18722 0.0647497020427373 0.208739680046262 MPHOSPH8/ATF7IP/HP1BP3 3 GO:2000107 negative regulation of leukocyte apoptotic process 3/376 46/18722 0.0647497020427373 0.208739680046262 CCL5/IL7R/TSC22D3 3 GO:0050728 negative regulation of inflammatory response 7/376 176/18722 0.0651049516963247 0.209646927435463 CST7/PTPRC/RORA/FYN/PTGER4/TNFAIP3/ZFP36 7 GO:0030502 negative regulation of bone mineralization 2/376 21/18722 0.0657344559571839 0.209646927435463 SRGN/CCL3 2 GO:0033962 P-body assembly 2/376 21/18722 0.0657344559571839 0.209646927435463 CNOT6L/DDX6 2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 2/376 21/18722 0.0657344559571839 0.209646927435463 GMFG/WAS 2 GO:0042454 ribonucleoside catabolic process 2/376 21/18722 0.0657344559571839 0.209646927435463 APOBEC3G/APOBEC3C 2 GO:0043373 CD4-positive, alpha-beta T cell lineage commitment 2/376 21/18722 0.0657344559571839 0.209646927435463 SPN/STAT3 2 GO:0043576 regulation of respiratory gaseous exchange 2/376 21/18722 0.0657344559571839 0.209646927435463 NR4A2/GLS 2 GO:0046597 negative regulation of viral entry into host cell 2/376 21/18722 0.0657344559571839 0.209646927435463 IFITM1/IFITM2 2 GO:0050849 negative regulation of calcium-mediated signaling 2/376 21/18722 0.0657344559571839 0.209646927435463 PLEK/TBC1D10C 2 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 2/376 21/18722 0.0657344559571839 0.209646927435463 SPON2/LAPTM5 2 GO:0072111 cell proliferation involved in kidney development 2/376 21/18722 0.0657344559571839 0.209646927435463 STAT1/CFLAR 2 GO:0099515 actin filament-based transport 2/376 21/18722 0.0657344559571839 0.209646927435463 SUN2/MYO1F 2 GO:2001014 regulation of skeletal muscle cell differentiation 2/376 21/18722 0.0657344559571839 0.209646927435463 DDX5/DDX17 2 GO:0071560 cellular response to transforming growth factor beta stimulus 9/376 250/18722 0.0661545534498228 0.210813235705644 ZFP36L2/XCL1/FYN/TGFB1/JUN/FOS/ZEB2/STAT3/CFLAR 9 GO:0046700 heterocycle catabolic process 14/376 445/18722 0.0663470680856256 0.211252990001478 ZFP36L2/APOBEC3G/ISG20/VIM/APOBEC3C/DDX5/ATM/ZFP36/PABPC1/BTG2/SAMHD1/CNOT6L/TNRC6B/ROCK1 14 GO:0033138 positive regulation of peptidyl-serine phosphorylation 5/376 108/18722 0.0666681269565472 0.211791015056398 TNF/STK4/TGFB1/CD44/TERF2IP 5 GO:0031100 animal organ regeneration 4/376 76/18722 0.0666720026374275 0.211791015056398 LCP1/UCP2/RPL19/SRSF5 4 GO:0051302 regulation of cell division 7/376 177/18722 0.0666800099016273 0.211791015056398 TXNIP/CALM1/TGFB1/LBH/RBL2/EVI2B/CDC42 7 GO:0010799 regulation of peptidyl-threonine phosphorylation 3/376 47/18722 0.0681772361073044 0.216192135773981 CALM1/DDIT4/TGFB1 3 GO:0045601 regulation of endothelial cell differentiation 3/376 47/18722 0.0681772361073044 0.216192135773981 TNF/BTG1/ROCK1 3 GO:0009266 response to temperature stimulus 7/376 178/18722 0.0682778938713313 0.216334291701888 PLAC8/CXCR4/ATM/CASP8/FOS/UCP2/NFKBIA 7 GO:0030010 establishment of cell polarity 6/376 143/18722 0.0688198967418329 0.217873447609969 MSN/CYTH1/RAP1B/SLC9A3R1/CDC42/ROCK1 6 GO:0006874 cellular calcium ion homeostasis 14/376 448/18722 0.069264488747453 0.218925338201484 CCL5/PTPRC/CD52/XCL1/CORO1A/GPR65/FYN/LCK/CYBA/CALM1/CXCR4/PTGER4/CCL3/PTPN6 14 GO:0000380 alternative mRNA splicing, via spliceosome 4/376 77/18722 0.0692651521638759 0.218925338201484 CELF2/DDX5/MBNL1/DDX17 4 GO:0001503 ossification 13/376 408/18722 0.069359698404391 0.219045502295856 IFITM1/RUNX3/SRGN/TNF/DDX5/PTGER4/CCL3/TGFB1/JUNB/SEMA4D/JUND/ISG15/CLIC1 13 GO:0060485 mesenchyme development 10/376 291/18722 0.070032318681019 0.220989604958427 EOMES/S100A4/DDX5/TGFB1/FLNA/STAT1/SEMA4D/GLIPR2/DDX17/ROCK1 10 GO:0033135 regulation of peptidyl-serine phosphorylation 6/376 144/18722 0.070663310494983 0.222646282171391 TNF/DDIT4/STK4/TGFB1/CD44/TERF2IP 6 GO:0002377 immunoglobulin production 8/376 216/18722 0.0706722392440801 0.222646282171391 PTPRC/B2M/HLA-E/XCL1/TNF/TGFB1/XBP1/SAMHD1 8 GO:0090174 organelle membrane fusion 5/376 110/18722 0.0709330424781295 0.223286384730099 CORO1A/PIP4K2A/SAMD9/RAB8B/VAMP2 5 GO:0006907 pinocytosis 2/376 22/18722 0.0713757416761941 0.223836997191042 PYCARD/CDC42 2 GO:0099563 modification of synaptic structure 2/376 22/18722 0.0713757416761941 0.223836997191042 PFN1/CDC42 2 GO:1900543 negative regulation of purine nucleotide metabolic process 2/376 22/18722 0.0713757416761941 0.223836997191042 DDIT4/STAT3 2 GO:2000114 regulation of establishment of cell polarity 2/376 22/18722 0.0713757416761941 0.223836997191042 RAP1B/ROCK1 2 GO:0002673 regulation of acute inflammatory response 3/376 48/18722 0.0716856034875052 0.223836997191042 HLA-E/ALOX5AP/TNF 3 GO:0010569 regulation of double-strand break repair via homologous recombination 3/376 48/18722 0.0716856034875052 0.223836997191042 WAS/TERF2IP/ACTR2 3 GO:0032527 protein exit from endoplasmic reticulum 3/376 48/18722 0.0716856034875052 0.223836997191042 SORL1/CD81/GCC2 3 GO:0043303 mast cell degranulation 3/376 48/18722 0.0716856034875052 0.223836997191042 RAC2/RASGRP1/LAT 3 GO:1902003 regulation of amyloid-beta formation 3/376 48/18722 0.0716856034875052 0.223836997191042 TNF/SORL1/ROCK1 3 GO:1903053 regulation of extracellular matrix organization 3/376 48/18722 0.0716856034875052 0.223836997191042 ETS1/TGFB1/CFLAR 3 GO:0030500 regulation of bone mineralization 4/376 78/18722 0.0719095940763175 0.224175122321585 SRGN/CCL3/TGFB1/ISG15 4 GO:0043297 apical junction assembly 4/376 78/18722 0.0719095940763175 0.224175122321585 TNF/MTDH/PRKCH/ROCK1 4 GO:0044270 cellular nitrogen compound catabolic process 14/376 451/18722 0.0722656989348741 0.225104166698261 ZFP36L2/APOBEC3G/ISG20/VIM/APOBEC3C/DDX5/ATM/ZFP36/PABPC1/BTG2/SAMHD1/CNOT6L/TNRC6B/ROCK1 14 GO:0006479 protein methylation 7/376 181/18722 0.0732085692661812 0.227310261142991 BTG1/KMT2A/KMT2E/BTG2/MLLT6/PRMT2/ATRX 7 GO:0008213 protein alkylation 7/376 181/18722 0.0732085692661812 0.227310261142991 BTG1/KMT2A/KMT2E/BTG2/MLLT6/PRMT2/ATRX 7 GO:0045766 positive regulation of angiogenesis 7/376 181/18722 0.0732085692661812 0.227310261142991 ETS1/JAK1/BTG1/CXCR4/MTDH/XBP1/STAT3 7 GO:1904018 positive regulation of vasculature development 7/376 181/18722 0.0732085692661812 0.227310261142991 ETS1/JAK1/BTG1/CXCR4/MTDH/XBP1/STAT3 7 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 6/376 146/18722 0.0744349255152659 0.230933015509732 GPR65/GNG2/ADGRE5/PTGER4/SLC9A3R1/AKAP13 6 GO:0000245 spliceosomal complex assembly 4/376 79/18722 0.0746049390843146 0.23109345735718 CELF2/SRSF5/SCAF11/SF1 4 GO:0010038 response to metal ion 12/376 373/18722 0.0746059135880859 0.23109345735718 B2M/TXNIP/CRIP1/ALOX5AP/CALM1/JUNB/CASP8/JUN/FOS/JUND/DUSP1/FOSB 12 GO:0002279 mast cell activation involved in immune response 3/376 49/18722 0.0752733845786325 0.231679400510088 RAC2/RASGRP1/LAT 3 GO:0006376 mRNA splice site selection 3/376 49/18722 0.0752733845786325 0.231679400510088 CELF2/SRSF5/SF1 3 GO:0008038 neuron recognition 3/376 49/18722 0.0752733845786325 0.231679400510088 CXCR4/YWHAZ/EMB 3 GO:0034332 adherens junction organization 3/376 49/18722 0.0752733845786325 0.231679400510088 ACTB/CSK/CDC42 3 GO:0035088 establishment or maintenance of apical/basal cell polarity 3/376 49/18722 0.0752733845786325 0.231679400510088 MSN/SLC9A3R1/CDC42 3 GO:0061245 establishment or maintenance of bipolar cell polarity 3/376 49/18722 0.0752733845786325 0.231679400510088 MSN/SLC9A3R1/CDC42 3 GO:0070741 response to interleukin-6 3/376 49/18722 0.0752733845786325 0.231679400510088 JAK1/SELPLG/STAT3 3 GO:0072091 regulation of stem cell proliferation 3/376 49/18722 0.0752733845786325 0.231679400510088 PTPRC/N4BP2L2/PIM1 3 GO:0001889 liver development 6/376 147/18722 0.0763630392936022 0.233795085233814 TNFAIP3/UCP2/XBP1/RPL19/SRSF5/CFLAR 6 GO:0048193 Golgi vesicle transport 10/376 296/18722 0.0764730284503368 0.233795085233814 RAB8B/LAPTM5/CSK/VAMP2/SORL1/TAPBP/VPS13C/MACF1/GCC2/VAMP5 10 GO:0022618 ribonucleoprotein complex assembly 8/376 220/18722 0.0767579451183378 0.233795085233814 CELF2/ATM/RPL10/RPS27/RPL3/SRSF5/SCAF11/SF1 8 GO:0044706 multi-multicellular organism process 8/376 220/18722 0.0767579451183378 0.233795085233814 ETS1/ARHGDIB/PRDM1/JUNB/FOS/UCP2/LNPEP/FOSB 8 GO:0002363 alpha-beta T cell lineage commitment 2/376 23/18722 0.0771674616810446 0.233795085233814 SPN/STAT3 2 GO:0006929 substrate-dependent cell migration 2/376 23/18722 0.0771674616810446 0.233795085233814 PTPRC/STK4 2 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 2/376 23/18722 0.0771674616810446 0.233795085233814 CBLB/SLC9A3R1 2 GO:0010888 negative regulation of lipid storage 2/376 23/18722 0.0771674616810446 0.233795085233814 TNF/NFKBIA 2 GO:0033081 regulation of T cell differentiation in thymus 2/376 23/18722 0.0771674616810446 0.233795085233814 IL7R/RASGRP1 2 GO:0034695 response to prostaglandin E 2/376 23/18722 0.0771674616810446 0.233795085233814 GNG2/PTGER4 2 GO:0035162 embryonic hemopoiesis 2/376 23/18722 0.0771674616810446 0.233795085233814 STK4/KMT2A 2 GO:0035994 response to muscle stretch 2/376 23/18722 0.0771674616810446 0.233795085233814 FOS/NFKBIA 2 GO:0043369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 2/376 23/18722 0.0771674616810446 0.233795085233814 SPN/STAT3 2 GO:0045662 negative regulation of myoblast differentiation 2/376 23/18722 0.0771674616810446 0.233795085233814 TNF/TGFB1 2 GO:0045943 positive regulation of transcription by RNA polymerase I 2/376 23/18722 0.0771674616810446 0.233795085233814 LYAR/NCL 2 GO:0045980 negative regulation of nucleotide metabolic process 2/376 23/18722 0.0771674616810446 0.233795085233814 DDIT4/STAT3 2 GO:0050765 negative regulation of phagocytosis 2/376 23/18722 0.0771674616810446 0.233795085233814 CNN2/CSK 2 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 2/376 23/18722 0.0771674616810446 0.233795085233814 CD53/TYROBP 2 GO:1903306 negative regulation of regulated secretory pathway 2/376 23/18722 0.0771674616810446 0.233795085233814 HLA-F/RAP1B 2 GO:2001169 regulation of ATP biosynthetic process 2/376 23/18722 0.0771674616810446 0.233795085233814 TMSB4X/STAT3 2 GO:0010212 response to ionizing radiation 6/376 148/18722 0.0783192854847903 0.236914310112071 PTPRC/CCND2/CYBA/IFI16/ATM/EEF1D 6 GO:0014074 response to purine-containing compound 6/376 148/18722 0.0783192854847903 0.236914310112071 JUN/STAT1/FOS/DUSP1/RAP1B/FOSB 6 GO:0001961 positive regulation of cytokine-mediated signaling pathway 3/376 50/18722 0.0789391202971905 0.237676061500865 TXK/CXCR4/LAPTM5 3 GO:0018023 peptidyl-lysine trimethylation 3/376 50/18722 0.0789391202971905 0.237676061500865 KMT2A/KMT2E/ATRX 3 GO:0038093 Fc receptor signaling pathway 3/376 50/18722 0.0789391202971905 0.237676061500865 PTPRC/FYN/FCER1G 3 GO:0045814 negative regulation of gene expression, epigenetic 3/376 50/18722 0.0789391202971905 0.237676061500865 EPC1/MPHOSPH8/ATF7IP 3 GO:0070231 T cell apoptotic process 3/376 50/18722 0.0789391202971905 0.237676061500865 CCL5/IL7R/TSC22D3 3 GO:1903747 regulation of establishment of protein localization to mitochondrion 3/376 50/18722 0.0789391202971905 0.237676061500865 GZMB/RAC2/TOMM7 3 GO:0002244 hematopoietic progenitor cell differentiation 5/376 114/18722 0.0799017853385227 0.239944722932511 PTPRC/PLEK/TGFB1/N4BP2L2/PTPN6 5 GO:0007041 lysosomal transport 5/376 114/18722 0.0799017853385227 0.239944722932511 LAPTM5/LYST/SORL1/GNPTAB/GCC2 5 GO:0051091 positive regulation of DNA-binding transcription factor activity 9/376 260/18722 0.0800102566719355 0.239944722932511 TNF/TRIM22/MTDH/PRKCH/TERF2IP/CARD16/PYCARD/STAT3/CFLAR 9 GO:0090150 establishment of protein localization to membrane 9/376 260/18722 0.0800102566719355 0.239944722932511 GZMB/FYN/CALM1/ITGB2/RAB8B/CSK/VAMP2/MACF1/VAMP5 9 GO:0048708 astrocyte differentiation 4/376 81/18722 0.0801466611883567 0.239944722932511 TNF/VIM/ID2/STAT3 4 GO:1903533 regulation of protein targeting 4/376 81/18722 0.0801466611883567 0.239944722932511 RAC2/FYN/ITGB2/TOMM7 4 GO:2000106 regulation of leukocyte apoptotic process 4/376 81/18722 0.0801466611883567 0.239944722932511 CCL5/IL7R/TSC22D3/CD3G 4 GO:0018209 peptidyl-serine modification 11/376 338/18722 0.0801879783735746 0.239944722932511 TNF/DDIT4/STK4/TGFB1/ATM/CD44/PRKCH/TERF2IP/RPS6KA3/CLK1/ROCK1 11 GO:0051321 meiotic cell cycle 9/376 261/18722 0.0814858576115226 0.243640199262847 MYBL1/PRKACB/ATM/SUN2/DUSP1/ACTR3/ACTR2/ATRX/CENPC 9 GO:0055074 calcium ion homeostasis 14/376 460/18722 0.0817771025168572 0.244082637662316 CCL5/PTPRC/CD52/XCL1/CORO1A/GPR65/FYN/LCK/CYBA/CALM1/CXCR4/PTGER4/CCL3/PTPN6 14 GO:1902115 regulation of organelle assembly 7/376 186/18722 0.08188272910122 0.244082637662316 LCP1/MSN/TNF/PIP4K2A/CYLD/ODF2L/CNOT6L 7 GO:0016050 vesicle organization 10/376 300/18722 0.0818831521840721 0.244082637662316 CORO1A/SRGN/PIP4K2A/SAMD9/RAB29/RAB27A/RAB8B/ZEB2/VAMP2/LYST 10 GO:0030278 regulation of ossification 5/376 115/18722 0.0822345373029622 0.244082637662316 SRGN/PTGER4/CCL3/TGFB1/ISG15 5 GO:0061008 hepaticobiliary system development 6/376 150/18722 0.0823159120243637 0.244082637662316 TNFAIP3/UCP2/XBP1/RPL19/SRSF5/CFLAR 6 GO:0045661 regulation of myoblast differentiation 3/376 51/18722 0.0826813154910801 0.244082637662316 TNF/BTG1/TGFB1 3 GO:0071622 regulation of granulocyte chemotaxis 3/376 51/18722 0.0826813154910801 0.244082637662316 CCL5/RAC2/XCL1 3 GO:1903307 positive regulation of regulated secretory pathway 3/376 51/18722 0.0826813154910801 0.244082637662316 HLA-F/ITGB2/RAB27A 3 GO:0009205 purine ribonucleoside triphosphate metabolic process 4/376 82/18722 0.0829921420667584 0.244082637662316 TMSB4X/GIMAP7/TGFB1/STAT3 4 GO:0060395 SMAD protein signal transduction 4/376 82/18722 0.0829921420667584 0.244082637662316 VIM/TGFB1/JUN/FOS 4 GO:2001252 positive regulation of chromosome organization 4/376 82/18722 0.0829921420667584 0.244082637662316 ATM/MPHOSPH8/ATRX/ATF7IP 4 GO:0002922 positive regulation of humoral immune response 2/376 24/18722 0.0831013356097533 0.244082637662316 PTPRC/TNF 2 GO:0006213 pyrimidine nucleoside metabolic process 2/376 24/18722 0.0831013356097533 0.244082637662316 APOBEC3G/APOBEC3C 2 GO:0010155 regulation of proton transport 2/376 24/18722 0.0831013356097533 0.244082637662316 TMSB4X/SLC9A3R1 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/376 24/18722 0.0831013356097533 0.244082637662316 TMSB4X/STAT3 2 GO:0032528 microvillus organization 2/376 24/18722 0.0831013356097533 0.244082637662316 FXYD5/SLC9A3R1 2 GO:0043302 positive regulation of leukocyte degranulation 2/376 24/18722 0.0831013356097533 0.244082637662316 HLA-F/ITGB2 2 GO:0051000 positive regulation of nitric-oxide synthase activity 2/376 24/18722 0.0831013356097533 0.244082637662316 TNF/CALM1 2 GO:0051043 regulation of membrane protein ectodomain proteolysis 2/376 24/18722 0.0831013356097533 0.244082637662316 TNF/ROCK1 2 GO:0090023 positive regulation of neutrophil chemotaxis 2/376 24/18722 0.0831013356097533 0.244082637662316 RAC2/XCL1 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/376 24/18722 0.0831013356097533 0.244082637662316 TMSB4X/STAT3 2 GO:1903077 negative regulation of protein localization to plasma membrane 2/376 24/18722 0.0831013356097533 0.244082637662316 TGFB1/CSK 2 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 2/376 24/18722 0.0831013356097533 0.244082637662316 CYBA/RAB27A 2 GO:0006913 nucleocytoplasmic transport 10/376 301/18722 0.0832715476102148 0.244082637662316 TXNIP/TGFB1/FLNA/SP100/PIK3R1/CBLB/AKAP13/STAT3/NFKBIA/PPP1R12A 10 GO:0042063 gliogenesis 10/376 301/18722 0.0832715476102148 0.244082637662316 TNF/CXCR4/VIM/CCL3/TGFB1/ID2/SUN2/PRKCH/CSK/STAT3 10 GO:0051169 nuclear transport 10/376 301/18722 0.0832715476102148 0.244082637662316 TXNIP/TGFB1/FLNA/SP100/PIK3R1/CBLB/AKAP13/STAT3/NFKBIA/PPP1R12A 10 GO:0018107 peptidyl-threonine phosphorylation 5/376 116/18722 0.0846031641709405 0.247798383342702 CALM1/DDIT4/TGFB1/CLK1/ROCK1 5 GO:0050769 positive regulation of neurogenesis 8/376 225/18722 0.0847946302329867 0.248171595281589 TNF/CXCR4/TGFB1/ID2/SEMA4D/PRKCH/MACF1/ACTR2 8 GO:0006816 calcium ion transport 13/376 422/18722 0.0848940414934418 0.248275027009122 CCL4/CCL5/PTPRC/XCL1/CORO1A/FYN/LCK/CYBA/CALM1/CXCR4/CCL3/EPB41/PTPN6 13 GO:0031397 negative regulation of protein ubiquitination 4/376 83/18722 0.0858867352000124 0.25098876236806 FYN/TNFAIP3/ISG15/IVNS1ABP 4 GO:0051496 positive regulation of stress fiber assembly 3/376 52/18722 0.0864984422046097 0.252395680378662 GPR65/EVL/CDC42 3 GO:2000378 negative regulation of reactive oxygen species metabolic process 3/376 52/18722 0.0864984422046097 0.252395680378662 FYN/STAT3/CFLAR 3 GO:0044772 mitotic cell cycle phase transition 13/376 424/18722 0.0872791463446421 0.254482085843106 ZFP36L2/CCND2/CALM1/ATM/CDKN2D/RBL2/PSME1/ID2/DUSP1/KMT2E/PTPN6/TAOK3/PRMT2 13 GO:0014706 striated muscle tissue development 12/376 384/18722 0.0879314323932195 0.255998723158321 HOPX/DDX5/TGFB1/FOS/ID2/BTG2/AKAP13/PIM1/CDC42/CFLAR/VAMP5/DDX17 12 GO:0042692 muscle cell differentiation 12/376 384/18722 0.0879314323932195 0.255998723158321 HOPX/RORA/SYNE1/CD53/TGFB1/ID2/XBP1/AKAP13/EPC1/CD81/ACTG1/CFLAR 12 GO:0071826 ribonucleoprotein complex subunit organization 8/376 227/18722 0.0881427371610151 0.256421251125325 CELF2/ATM/RPL10/RPS27/RPL3/SRSF5/SCAF11/SF1 8 GO:0097061 dendritic spine organization 4/376 84/18722 0.0888299384428819 0.256900553597127 FYN/CFL1/CDC42/ACTR2 4 GO:0030318 melanocyte differentiation 2/376 25/18722 0.0891693534420995 0.256900553597127 RAB27A/ZEB2 2 GO:0031579 membrane raft organization 2/376 25/18722 0.0891693534420995 0.256900553597127 CD2/PTPRC 2 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 2/376 25/18722 0.0891693534420995 0.256900553597127 TNFAIP3/CARD16 2 GO:0032878 regulation of establishment or maintenance of cell polarity 2/376 25/18722 0.0891693534420995 0.256900553597127 RAP1B/ROCK1 2 GO:0035902 response to immobilization stress 2/376 25/18722 0.0891693534420995 0.256900553597127 FOS/ACTR2 2 GO:0050995 negative regulation of lipid catabolic process 2/376 25/18722 0.0891693534420995 0.256900553597127 TNF/SORL1 2 GO:0060074 synapse maturation 2/376 25/18722 0.0891693534420995 0.256900553597127 PFN1/YWHAZ 2 GO:0062149 detection of stimulus involved in sensory perception of pain 2/376 25/18722 0.0891693534420995 0.256900553597127 FYN/CXCR4 2 GO:0098581 detection of external biotic stimulus 2/376 25/18722 0.0891693534420995 0.256900553597127 HLA-A/HLA-B 2 GO:1903055 positive regulation of extracellular matrix organization 2/376 25/18722 0.0891693534420995 0.256900553597127 TGFB1/CFLAR 2 GO:1904385 cellular response to angiotensin 2/376 25/18722 0.0891693534420995 0.256900553597127 CYBA/ROCK1 2 GO:1905564 positive regulation of vascular endothelial cell proliferation 2/376 25/18722 0.0891693534420995 0.256900553597127 ITGA4/STAT3 2 GO:0006413 translational initiation 5/376 118/18722 0.0894472391062728 0.257509696535518 CCL5/TNF/EIF1/EIF4A2/PPP1R15A 5 GO:0019439 aromatic compound catabolic process 14/376 467/18722 0.0897065051127543 0.258064370684427 ZFP36L2/APOBEC3G/ISG20/VIM/APOBEC3C/DDX5/ATM/ZFP36/PABPC1/BTG2/SAMHD1/CNOT6L/TNRC6B/ROCK1 14 GO:0043620 regulation of DNA-templated transcription in response to stress 3/376 53/18722 0.0903889428032465 0.259834683503398 KLF2/JUN/RPS6KA3 3 GO:0030856 regulation of epithelial cell differentiation 6/376 154/18722 0.0906434229015527 0.260373064302088 TNF/BTG1/ZFP36/STAT1/PRKCH/ROCK1 6 GO:0001649 osteoblast differentiation 8/376 229/18722 0.0915668557593029 0.26283078967948 IFITM1/TNF/DDX5/CCL3/JUNB/SEMA4D/JUND/CLIC1 8 GO:0010507 negative regulation of autophagy 4/376 85/18722 0.0918212294575733 0.263365850590745 PTPN22/IL10RA/STAT3/MCL1 4 GO:0070482 response to oxygen levels 11/376 347/18722 0.0921902218038185 0.264228631279435 ETS1/MALAT1/RORA/CYBA/CXCR4/DDIT4/NR4A2/UCP2/CARD16/CFLAR/HP1BP3 11 GO:1903364 positive regulation of cellular protein catabolic process 6/376 155/18722 0.0927943735691414 0.265763634575331 PYHIN1/MSN/TNFAIP3/LAPTM5/RNF19A/CD81 6 GO:0016197 endosomal transport 8/376 230/18722 0.093307348173924 0.267035431443099 TBC1D10C/ARL4C/WAS/RAB29/LYST/SORL1/LEPROTL1/GCC2 8 GO:0030520 intracellular estrogen receptor signaling pathway 3/376 54/18722 0.0943512329628705 0.269823636701936 DDX5/LBH/DDX17 3 GO:0071774 response to fibroblast growth factor 5/376 120/18722 0.0944322825902348 0.269856264776666 CCL5/ZFP36L2/CD44/ZFP36/IER2 5 GO:0034103 regulation of tissue remodeling 4/376 86/18722 0.0948600664960006 0.270127632390833 TGFB1/TNFAIP3/CSK/ROCK1 4 GO:1903510 mucopolysaccharide metabolic process 4/376 86/18722 0.0948600664960006 0.270127632390833 TGFB1/CD44/PIM1/CHST12 4 GO:2001251 negative regulation of chromosome organization 4/376 86/18722 0.0948600664960006 0.270127632390833 ATM/DUSP1/TERF2IP/ATRX 4 GO:0001764 neuron migration 6/376 156/18722 0.0949727300227804 0.270127632390833 FYN/CXCR4/DDIT4/NR4A2/FLNA/STAT3 6 GO:0002407 dendritic cell chemotaxis 2/376 26/18722 0.0953637680285573 0.270127632390833 CCL5/CXCR4 2 GO:0002418 immune response to tumor cell 2/376 26/18722 0.0953637680285573 0.270127632390833 PRF1/HLA-A 2 GO:0006027 glycosaminoglycan catabolic process 2/376 26/18722 0.0953637680285573 0.270127632390833 TGFB1/CD44 2 GO:0009164 nucleoside catabolic process 2/376 26/18722 0.0953637680285573 0.270127632390833 APOBEC3G/APOBEC3C 2 GO:0070102 interleukin-6-mediated signaling pathway 2/376 26/18722 0.0953637680285573 0.270127632390833 JAK1/STAT3 2 GO:0071425 hematopoietic stem cell proliferation 2/376 26/18722 0.0953637680285573 0.270127632390833 N4BP2L2/PIM1 2 GO:1904376 negative regulation of protein localization to cell periphery 2/376 26/18722 0.0953637680285573 0.270127632390833 TGFB1/CSK 2 GO:1905523 positive regulation of macrophage migration 2/376 26/18722 0.0953637680285573 0.270127632390833 CCL5/CCL3 2 GO:1901987 regulation of cell cycle phase transition 12/376 390/18722 0.0957850039868442 0.271122637289278 ZFP36L2/CCND2/ATM/CDKN2D/RBL2/PSME1/ID2/DUSP1/KMT2E/PTPN6/TAOK3/PRMT2 12 GO:0001704 formation of primary germ layer 5/376 121/18722 0.0969770762574127 0.274296474815675 DUSP2/EOMES/ITGB2/ITGA4/DUSP1 5 GO:0045861 negative regulation of proteolysis 11/376 351/18722 0.0978564302380309 0.276581814130102 CST7/TNF/IFI16/BST2/CDKN2D/CD44/CARD16/SORL1/RPS6KA3/ROCK1/DNAJC1 11 GO:0001776 leukocyte homeostasis 4/376 87/18722 0.0979458891760355 0.276632886703453 TSC22D3/CORO1A/LAT/TNFAIP3 4 GO:0003229 ventricular cardiac muscle tissue development 3/376 55/18722 0.0983837045281543 0.277061667911772 HOPX/TGFB1/ID2 3 GO:0006360 transcription by RNA polymerase I 3/376 55/18722 0.0983837045281543 0.277061667911772 FLNA/LYAR/NCL 3 GO:0045620 negative regulation of lymphocyte differentiation 3/376 55/18722 0.0983837045281543 0.277061667911772 RUNX3/IRF1/ID2 3 GO:1902991 regulation of amyloid precursor protein catabolic process 3/376 55/18722 0.0983837045281543 0.277061667911772 TNF/SORL1/ROCK1 3 GO:0001667 ameboidal-type cell migration 14/376 475/18722 0.0993425062687562 0.279558614227618 TMSB4X/ETS1/ARHGDIB/EVL/TNF/ITGA4/TGFB1/PFN1/SEMA4D/SP100/GLIPR2/ZEB2/MACF1/ROCK1 14 GO:0051928 positive regulation of calcium ion transport 5/376 122/18722 0.0995563798307757 0.279957163892784 CCL4/CCL5/XCL1/CALM1/CCL3 5 GO:1903169 regulation of calcium ion transmembrane transport 6/376 159/18722 0.101670953117124 0.284270357330364 XCL1/CORO1A/FYN/CYBA/CALM1/PTPN6 6 GO:0000027 ribosomal large subunit assembly 2/376 27/18722 0.101677087809002 0.284270357330364 RPL10/RPL3 2 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 2/376 27/18722 0.101677087809002 0.284270357330364 PTPRC/FYN 2 GO:0032967 positive regulation of collagen biosynthetic process 2/376 27/18722 0.101677087809002 0.284270357330364 VIM/TGFB1 2 GO:0034143 regulation of toll-like receptor 4 signaling pathway 2/376 27/18722 0.101677087809002 0.284270357330364 PTPN22/TNFAIP3 2 GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 2/376 27/18722 0.101677087809002 0.284270357330364 PTPRC/FYN 2 GO:0045830 positive regulation of isotype switching 2/376 27/18722 0.101677087809002 0.284270357330364 PTPRC/TGFB1 2 GO:0071624 positive regulation of granulocyte chemotaxis 2/376 27/18722 0.101677087809002 0.284270357330364 RAC2/XCL1 2 GO:0010332 response to gamma radiation 3/376 56/18722 0.102484728244552 0.285498434182342 PTPRC/CYBA/ATM 3 GO:0031529 ruffle organization 3/376 56/18722 0.102484728244552 0.285498434182342 PLEK/EVL/PFN1 3 GO:0043388 positive regulation of DNA binding 3/376 56/18722 0.102484728244552 0.285498434182342 PYHIN1/CALM1/TGFB1 3 GO:0048008 platelet-derived growth factor receptor signaling pathway 3/376 56/18722 0.102484728244552 0.285498434182342 TXNIP/CBLB/SLC9A3R1 3 GO:0051653 spindle localization 3/376 56/18722 0.102484728244552 0.285498434182342 CFL1/ACTR3/ACTR2 3 GO:0071248 cellular response to metal ion 7/376 197/18722 0.102955961756704 0.28660513779255 B2M/ALOX5AP/JUNB/JUN/FOS/JUND/FOSB 7 GO:0043270 positive regulation of ion transport 9/376 275/18722 0.103861741355941 0.288919057971479 CCL4/CCL5/TMSB4X/XCL1/CALM1/CCL3/FLNA/SLC9A3R1/MLLT6 9 GO:0009199 ribonucleoside triphosphate metabolic process 4/376 89/18722 0.104256161372372 0.289808196067391 TMSB4X/GIMAP7/TGFB1/STAT3 4 GO:0043414 macromolecule methylation 10/376 316/18722 0.105818032526864 0.293938979241289 BTG1/FOS/KMT2A/KMT2E/BTG2/MLLT6/PRMT2/MPHOSPH8/ATRX/ATF7IP 10 GO:0006754 ATP biosynthetic process 3/376 57/18722 0.106652656368242 0.295223781628852 TMSB4X/TGFB1/STAT3 3 GO:0033619 membrane protein proteolysis 3/376 57/18722 0.106652656368242 0.295223781628852 TNF/TGFB1/ROCK1 3 GO:0034205 amyloid-beta formation 3/376 57/18722 0.106652656368242 0.295223781628852 TNF/SORL1/ROCK1 3 GO:0060760 positive regulation of response to cytokine stimulus 3/376 57/18722 0.106652656368242 0.295223781628852 TXK/CXCR4/LAPTM5 3 GO:0010631 epithelial cell migration 11/376 357/18722 0.106737682080522 0.295223781628852 TMSB4X/ETS1/EVL/TNF/TGFB1/PFN1/SP100/GLIPR2/ZEB2/MACF1/ROCK1 11 GO:1904062 regulation of cation transmembrane transport 11/376 357/18722 0.106737682080522 0.295223781628852 TMSB4X/XCL1/CORO1A/FYN/CYBA/CALM1/FXYD5/FLNA/VAMP2/SLC9A3R1/PTPN6 11 GO:0035278 miRNA mediated inhibition of translation 4/376 90/18722 0.107479403843369 0.295830169598788 ZFP36/STAT3/DDX6/TNRC6B 4 GO:0040033 negative regulation of translation, ncRNA-mediated 4/376 90/18722 0.107479403843369 0.295830169598788 ZFP36/STAT3/DDX6/TNRC6B 4 GO:0046849 bone remodeling 4/376 90/18722 0.107479403843369 0.295830169598788 RAC2/TGFB1/TNFAIP3/CSK 4 GO:0018210 peptidyl-threonine modification 5/376 125/18722 0.107498624230738 0.295830169598788 CALM1/DDIT4/TGFB1/CLK1/ROCK1 5 GO:0051053 negative regulation of DNA metabolic process 5/376 125/18722 0.107498624230738 0.295830169598788 GZMA/ATM/KMT2A/DUSP1/TERF2IP 5 GO:0070585 protein localization to mitochondrion 5/376 125/18722 0.107498624230738 0.295830169598788 GZMB/RAC2/CALM1/ISG15/TOMM7 5 GO:0000423 mitophagy 2/376 28/18722 0.108102069716615 0.295830169598788 TOMM7/VPS13C 2 GO:0010575 positive regulation of vascular endothelial growth factor production 2/376 28/18722 0.108102069716615 0.295830169598788 RORA/TGFB1 2 GO:0010714 positive regulation of collagen metabolic process 2/376 28/18722 0.108102069716615 0.295830169598788 VIM/TGFB1 2 GO:0032801 receptor catabolic process 2/376 28/18722 0.108102069716615 0.295830169598788 TGFB1/LAPTM5 2 GO:0034123 positive regulation of toll-like receptor signaling pathway 2/376 28/18722 0.108102069716615 0.295830169598788 PTPN22/CYBA 2 GO:0045671 negative regulation of osteoclast differentiation 2/376 28/18722 0.108102069716615 0.295830169598788 CCL3/PIK3R1 2 GO:0060765 regulation of androgen receptor signaling pathway 2/376 28/18722 0.108102069716615 0.295830169598788 DDX5/PRMT2 2 GO:0080111 DNA demethylation 2/376 28/18722 0.108102069716615 0.295830169598788 APOBEC3G/APOBEC3C 2 GO:1990776 response to angiotensin 2/376 28/18722 0.108102069716615 0.295830169598788 CYBA/ROCK1 2 GO:0016049 cell growth 14/376 482/18722 0.108276986875586 0.296099734751514 CYBA/BTG1/CXCR4/ITGA4/BST2/TGFB1/CDKN2D/SEMA4D/CCDC85B/AKAP13/RPS6KA3/CDC42/MACF1/PRMT2 14 GO:0034250 positive regulation of cellular amide metabolic process 6/376 162/18722 0.108610920711403 0.296803468093572 CCL5/TNF/VIM/RPS4X/PABPC1/PPP1R15A 6 GO:0045974 regulation of translation, ncRNA-mediated 4/376 91/18722 0.110747219365815 0.301955426906674 ZFP36/STAT3/DDX6/TNRC6B 4 GO:0001954 positive regulation of cell-matrix adhesion 3/376 58/18722 0.110885825158245 0.301955426906674 CD3E/SKAP1/ROCK1 3 GO:0043506 regulation of JUN kinase activity 3/376 58/18722 0.110885825158245 0.301955426906674 PTPN22/TNF/TAOK3 3 GO:0045604 regulation of epidermal cell differentiation 3/376 58/18722 0.110885825158245 0.301955426906674 ZFP36/PRKCH/ROCK1 3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 3/376 58/18722 0.110885825158245 0.301955426906674 LCK/SLC9A3R1/MCL1 3 GO:0090132 epithelium migration 11/376 360/18722 0.111349377116884 0.303004800792082 TMSB4X/ETS1/EVL/TNF/TGFB1/PFN1/SP100/GLIPR2/ZEB2/MACF1/ROCK1 11 GO:0030048 actin filament-based movement 5/376 127/18722 0.112960823984883 0.307174170485207 WIPF1/WAS/FLNA/SUN2/MYO1F 5 GO:0072503 cellular divalent inorganic cation homeostasis 14/376 486/18722 0.113592727041365 0.308675888699361 CCL5/PTPRC/CD52/XCL1/CORO1A/GPR65/FYN/LCK/CYBA/CALM1/CXCR4/PTGER4/CCL3/PTPN6 14 GO:0060537 muscle tissue development 12/376 403/18722 0.114217883723181 0.309114742531121 HOPX/DDX5/TGFB1/FOS/ID2/BTG2/AKAP13/PIM1/CDC42/CFLAR/VAMP5/DDX17 12 GO:0001773 myeloid dendritic cell activation 2/376 29/18722 0.114631712262509 0.309114742531121 CD2/PYCARD 2 GO:0002360 T cell lineage commitment 2/376 29/18722 0.114631712262509 0.309114742531121 SPN/STAT3 2 GO:0010955 negative regulation of protein processing 2/376 29/18722 0.114631712262509 0.309114742531121 CST7/CARD16 2 GO:0070198 protein localization to chromosome, telomeric region 2/376 29/18722 0.114631712262509 0.309114742531121 TERF2IP/ATRX 2 GO:0071549 cellular response to dexamethasone stimulus 2/376 29/18722 0.114631712262509 0.309114742531121 DDIT4/CFLAR 2 GO:0072539 T-helper 17 cell differentiation 2/376 29/18722 0.114631712262509 0.309114742531121 RORA/STAT3 2 GO:0090025 regulation of monocyte chemotaxis 2/376 29/18722 0.114631712262509 0.309114742531121 CCL5/DUSP1 2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/376 29/18722 0.114631712262509 0.309114742531121 CDKN2D/CD44 2 GO:1902430 negative regulation of amyloid-beta formation 2/376 29/18722 0.114631712262509 0.309114742531121 SORL1/ROCK1 2 GO:1903318 negative regulation of protein maturation 2/376 29/18722 0.114631712262509 0.309114742531121 CST7/CARD16 2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 3/376 59/18722 0.115182557254794 0.309737966247278 TGFB1/PIK3R1/CDC42 3 GO:0051353 positive regulation of oxidoreductase activity 3/376 59/18722 0.115182557254794 0.309737966247278 CYBA/TNF/CALM1 3 GO:0090303 positive regulation of wound healing 3/376 59/18722 0.115182557254794 0.309737966247278 CXCR4/XBP1/ACTG1 3 GO:2000351 regulation of endothelial cell apoptotic process 3/376 59/18722 0.115182557254794 0.309737966247278 TNF/ITGA4/TNFAIP3 3 GO:0051701 biological process involved in interaction with host 7/376 203/18722 0.115580037572346 0.310577102038094 IFITM1/IFITM2/CXCR4/SELPLG/TRIM22/LGALS1/CD81 7 GO:1903320 regulation of protein modification by small protein conjugation or removal 8/376 242/18722 0.115654905352508 0.310577102038094 FYN/PTPN22/RASSF5/TNFAIP3/LAPTM5/ISG15/CBLB/IVNS1ABP 8 GO:0006979 response to oxidative stress 13/376 446/18722 0.116271126386646 0.312015661183001 ETS1/TXNIP/KLF2/FYN/BTG1/TNFAIP3/NR4A2/JUN/STAT1/FOS/UCP2/DUSP1/MCL1 13 GO:0106027 neuron projection organization 4/376 93/18722 0.117413986776888 0.314429301147507 FYN/CFL1/CDC42/ACTR2 4 GO:1901796 regulation of signal transduction by p53 class mediator 4/376 93/18722 0.117413986776888 0.314429301147507 PYHIN1/DDX5/ATM/CD44 4 GO:1902807 negative regulation of cell cycle G1/S phase transition 4/376 93/18722 0.117413986776888 0.314429301147507 ATM/CDKN2D/RBL2/PRMT2 4 GO:0032259 methylation 11/376 364/18722 0.117674480100017 0.314909261317381 PRDM1/BTG1/FOS/KMT2A/KMT2E/BTG2/MLLT6/PRMT2/MPHOSPH8/ATRX/ATF7IP 11 GO:1901888 regulation of cell junction assembly 7/376 204/18722 0.117759656321264 0.314919715834988 TNF/SEMA4D/PRKCH/RAP1B/MACF1/ACTG1/ROCK1 7 GO:0030307 positive regulation of cell growth 6/376 166/18722 0.118232750318754 0.315966832748394 CYBA/CXCR4/SEMA4D/RPS6KA3/CDC42/MACF1 6 GO:0090130 tissue migration 11/376 365/18722 0.11928704536615 0.318564645619455 TMSB4X/ETS1/EVL/TNF/TGFB1/PFN1/SP100/GLIPR2/ZEB2/MACF1/ROCK1 11 GO:0031638 zymogen activation 3/376 60/18722 0.11954116394794 0.318803861182565 IFI16/CASP8/PYCARD 3 GO:0042306 regulation of protein import into nucleus 3/376 60/18722 0.11954116394794 0.318803861182565 TGFB1/FLNA/PIK3R1 3 GO:1903034 regulation of response to wounding 6/376 167/18722 0.120702826184337 0.3205181371673 TNF/CXCR4/TNFAIP3/FLNA/XBP1/ACTG1 6 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 2/376 30/18722 0.121259248796713 0.3205181371673 CALM1/TGFB1 2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 2/376 30/18722 0.121259248796713 0.3205181371673 B2M/FCER1G 2 GO:0034694 response to prostaglandin 2/376 30/18722 0.121259248796713 0.3205181371673 GNG2/PTGER4 2 GO:0043032 positive regulation of macrophage activation 2/376 30/18722 0.121259248796713 0.3205181371673 CCL3/JUND 2 GO:0044030 regulation of DNA methylation 2/376 30/18722 0.121259248796713 0.3205181371673 KMT2A/MPHOSPH8 2 GO:0045070 positive regulation of viral genome replication 2/376 30/18722 0.121259248796713 0.3205181371673 CCL5/PABPC1 2 GO:0051491 positive regulation of filopodium assembly 2/376 30/18722 0.121259248796713 0.3205181371673 PIK3R1/CDC42 2 GO:0090151 establishment of protein localization to mitochondrial membrane 2/376 30/18722 0.121259248796713 0.3205181371673 GZMB/CALM1 2 GO:0090314 positive regulation of protein targeting to membrane 2/376 30/18722 0.121259248796713 0.3205181371673 FYN/ITGB2 2 GO:0140058 neuron projection arborization 2/376 30/18722 0.121259248796713 0.3205181371673 MACF1/ROCK1 2 GO:1903579 negative regulation of ATP metabolic process 2/376 30/18722 0.121259248796713 0.3205181371673 DDIT4/STAT3 2 GO:2000648 positive regulation of stem cell proliferation 2/376 30/18722 0.121259248796713 0.3205181371673 PTPRC/N4BP2L2 2 GO:0001701 in utero embryonic development 11/376 367/18722 0.122549517898226 0.323707826759117 KLF2/HOPX/EOMES/PRDM1/STK4/MBNL1/JUNB/CASP8/N4BP2L2/RPL13/CMTM3 11 GO:0042255 ribosome assembly 3/376 61/18722 0.123959947340207 0.326987607857932 RPL10/RPS27/RPL3 3 GO:0060997 dendritic spine morphogenesis 3/376 61/18722 0.123959947340207 0.326987607857932 CFL1/CDC42/ACTR2 3 GO:0007044 cell-substrate junction assembly 4/376 95/18722 0.124251160959564 0.327087804835809 TLN1/MACF1/ACTG1/ROCK1 4 GO:0042982 amyloid precursor protein metabolic process 4/376 95/18722 0.124251160959564 0.327087804835809 ITM2A/TNF/SORL1/ROCK1 4 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 4/376 95/18722 0.124251160959564 0.327087804835809 FYN/TNFAIP3/ISG15/IVNS1ABP 4 GO:0050679 positive regulation of epithelial cell proliferation 7/376 207/18722 0.124425821071029 0.32732522515291 CYBA/ITGA4/TNFAIP3/XBP1/STAT3/CDC42/CFLAR 7 GO:1901361 organic cyclic compound catabolic process 14/376 495/18722 0.126108819735807 0.331527595981175 ZFP36L2/APOBEC3G/ISG20/VIM/APOBEC3C/DDX5/ATM/ZFP36/PABPC1/BTG2/SAMHD1/CNOT6L/TNRC6B/ROCK1 14 GO:0002828 regulation of type 2 immune response 2/376 31/18722 0.127978140941252 0.333500535405079 XCL1/CD81 2 GO:0032509 endosome transport via multivesicular body sorting pathway 2/376 31/18722 0.127978140941252 0.333500535405079 LYST/LEPROTL1 2 GO:0033238 regulation of cellular amine metabolic process 2/376 31/18722 0.127978140941252 0.333500535405079 ITGB2/NR4A2 2 GO:0034656 nucleobase-containing small molecule catabolic process 2/376 31/18722 0.127978140941252 0.333500535405079 APOBEC3G/APOBEC3C 2 GO:0035510 DNA dealkylation 2/376 31/18722 0.127978140941252 0.333500535405079 APOBEC3G/APOBEC3C 2 GO:0048566 embryonic digestive tract development 2/376 31/18722 0.127978140941252 0.333500535405079 TNF/ID2 2 GO:0051569 regulation of histone H3-K4 methylation 2/376 31/18722 0.127978140941252 0.333500535405079 KMT2A/KMT2E 2 GO:0061099 negative regulation of protein tyrosine kinase activity 2/376 31/18722 0.127978140941252 0.333500535405079 PTPRC/CBLB 2 GO:0070633 transepithelial transport 2/376 31/18722 0.127978140941252 0.333500535405079 ACTB/ACTG1 2 GO:0070723 response to cholesterol 2/376 31/18722 0.127978140941252 0.333500535405079 CCL3/TGFB1 2 GO:0071480 cellular response to gamma radiation 2/376 31/18722 0.127978140941252 0.333500535405079 CYBA/ATM 2 GO:1900027 regulation of ruffle assembly 2/376 31/18722 0.127978140941252 0.333500535405079 EVL/PFN1 2 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2/376 31/18722 0.127978140941252 0.333500535405079 TNFAIP3/CFLAR 2 GO:0009116 nucleoside metabolic process 3/376 62/18722 0.128437202407055 0.33379889961592 APOBEC3G/APOBEC3C/APRT 3 GO:0010573 vascular endothelial growth factor production 3/376 62/18722 0.128437202407055 0.33379889961592 RORA/TNF/TGFB1 3 GO:0046824 positive regulation of nucleocytoplasmic transport 3/376 62/18722 0.128437202407055 0.33379889961592 TGFB1/FLNA/PIK3R1 3 GO:1903078 positive regulation of protein localization to plasma membrane 3/376 62/18722 0.128437202407055 0.33379889961592 TNF/PIK3R1/PRKCH 3 GO:0045926 negative regulation of growth 8/376 249/18722 0.129909732187972 0.337399606051202 PLAC8/BTG1/STK4/BST2/TGFB1/CDKN2D/SEMA4D/CCDC85B 8 GO:0019216 regulation of lipid metabolic process 10/376 331/18722 0.131547920544783 0.341425446825877 RORA/TNF/PIP4K2A/TGFB1/ID2/DGKZ/SORL1/CDC42/CD81/SF1 10 GO:0022617 extracellular matrix disassembly 3/376 63/18722 0.132971218958736 0.344197377064195 ETS1/LCP1/TGFB1 3 GO:0030239 myofibril assembly 3/376 63/18722 0.132971218958736 0.344197377064195 AKAP13/ACTG1/CFLAR 3 GO:1904589 regulation of protein import 3/376 63/18722 0.132971218958736 0.344197377064195 TGFB1/FLNA/PIK3R1 3 GO:2000242 negative regulation of reproductive process 3/376 63/18722 0.132971218958736 0.344197377064195 ARHGDIB/PRKACB/DUSP1 3 GO:0061041 regulation of wound healing 5/376 134/18722 0.133092358583176 0.344280967630045 TNF/CXCR4/TNFAIP3/XBP1/ACTG1 5 GO:0003015 heart process 8/376 251/18722 0.134142466228187 0.345963952395723 HOPX/FYN/CELF2/CALM1/CXCR4/FLNA/AKAP13/CDC42 8 GO:0003180 aortic valve morphogenesis 2/376 32/18722 0.134782072191154 0.345963952395723 TGFB1/ROCK1 2 GO:0006026 aminoglycan catabolic process 2/376 32/18722 0.134782072191154 0.345963952395723 TGFB1/CD44 2 GO:0010743 regulation of macrophage derived foam cell differentiation 2/376 32/18722 0.134782072191154 0.345963952395723 PRKCH/NFKBIA 2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 2/376 32/18722 0.134782072191154 0.345963952395723 CDKN2D/TNFAIP3 2 GO:0045879 negative regulation of smoothened signaling pathway 2/376 32/18722 0.134782072191154 0.345963952395723 CD3E/PRKACB 2 GO:0090022 regulation of neutrophil chemotaxis 2/376 32/18722 0.134782072191154 0.345963952395723 RAC2/XCL1 2 GO:1901889 negative regulation of cell junction assembly 2/376 32/18722 0.134782072191154 0.345963952395723 TNF/ROCK1 2 GO:1903955 positive regulation of protein targeting to mitochondrion 2/376 32/18722 0.134782072191154 0.345963952395723 RAC2/TOMM7 2 GO:1905476 negative regulation of protein localization to membrane 2/376 32/18722 0.134782072191154 0.345963952395723 TGFB1/CSK 2 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 2/376 32/18722 0.134782072191154 0.345963952395723 XCL1/RUNX3 2 GO:0043473 pigmentation 4/376 98/18722 0.134814340159366 0.345963952395723 RAB29/RAB27A/ZEB2/LYST 4 GO:0010632 regulation of epithelial cell migration 9/376 292/18722 0.135262395562824 0.346884038918558 TMSB4X/ETS1/EVL/TNF/TGFB1/PFN1/SP100/GLIPR2/MACF1 9 GO:0000910 cytokinesis 6/376 173/18722 0.136050654426069 0.348320911759898 CALM1/SON/ACTR3/CDC42/ACTR2/ROCK1 6 GO:0051099 positive regulation of binding 6/376 173/18722 0.136050654426069 0.348320911759898 B2M/PYHIN1/CALM1/STK4/TGFB1/EPB41 6 GO:0001101 response to acid chemical 5/376 135/18722 0.136092351072125 0.348320911759898 KLF2/FYN/CYBA/TNF/XBP1 5 GO:0030837 negative regulation of actin filament polymerization 3/376 64/18722 0.137560283507056 0.351381739347293 TMSB4X/TMSB10/PFN1 3 GO:0046854 phosphatidylinositol phosphate biosynthetic process 3/376 64/18722 0.137560283507056 0.351381739347293 PIP4K2A/ATM/PIK3R1 3 GO:0055002 striated muscle cell development 3/376 64/18722 0.137560283507056 0.351381739347293 AKAP13/ACTG1/CFLAR 3 GO:0007631 feeding behavior 4/376 99/18722 0.138414523908832 0.353330882837104 FYN/FOS/GLS/STAT3 4 GO:0001659 temperature homeostasis 6/376 174/18722 0.138694490374155 0.353812475444272 TNF/PLAC8/CXCR4/UCP2/LNPEP/STAT3 6 GO:0034329 cell junction assembly 12/376 420/18722 0.14120314419528 0.356657209729256 TNF/MTDH/RAB29/ACTB/SEMA4D/TLN1/PRKCH/RAP1B/CDC42/MACF1/ACTG1/ROCK1 12 GO:0048771 tissue remodeling 6/376 175/18722 0.141362246088862 0.356657209729256 RAC2/TGFB1/TNFAIP3/FLNA/CSK/ROCK1 6 GO:0001881 receptor recycling 2/376 33/18722 0.14166494167931 0.356657209729256 RAB29/SORL1 2 GO:0001975 response to amphetamine 2/376 33/18722 0.14166494167931 0.356657209729256 CALM1/NR4A2 2 GO:0010165 response to X-ray 2/376 33/18722 0.14166494167931 0.356657209729256 CCND2/ATM 2 GO:0010737 protein kinase A signaling 2/376 33/18722 0.14166494167931 0.356657209729256 LCP1/PRKACB 2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 2/376 33/18722 0.14166494167931 0.356657209729256 TGFB1/CDC42 2 GO:0045920 negative regulation of exocytosis 2/376 33/18722 0.14166494167931 0.356657209729256 HLA-F/RAP1B 2 GO:0050974 detection of mechanical stimulus involved in sensory perception 2/376 33/18722 0.14166494167931 0.356657209729256 FYN/CXCR4 2 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 2/376 33/18722 0.14166494167931 0.356657209729256 EVL/ODF2L 2 GO:0150117 positive regulation of cell-substrate junction organization 2/376 33/18722 0.14166494167931 0.356657209729256 PIK3R1/ROCK1 2 GO:1902275 regulation of chromatin organization 2/376 33/18722 0.14166494167931 0.356657209729256 MPHOSPH8/ATF7IP 2 GO:1902992 negative regulation of amyloid precursor protein catabolic process 2/376 33/18722 0.14166494167931 0.356657209729256 SORL1/ROCK1 2 GO:1904030 negative regulation of cyclin-dependent protein kinase activity 2/376 33/18722 0.14166494167931 0.356657209729256 CDKN2D/TNFAIP3 2 GO:0006910 phagocytosis, recognition 4/376 100/18722 0.142053051316439 0.356657209729256 TRDC/TRBC1/TRBC2/SPON2 4 GO:0061640 cytoskeleton-dependent cytokinesis 4/376 100/18722 0.142053051316439 0.356657209729256 SON/ACTR3/ACTR2/ROCK1 4 GO:0022613 ribonucleoprotein complex biogenesis 13/376 463/18722 0.142096056501802 0.356657209729256 ISG20/CELF2/ATM/RPL10/RPS27/GTF3A/RPL35A/RPL3/LYAR/SRSF5/SCAF11/SF1/DDX17 13 GO:0045471 response to ethanol 5/376 137/18722 0.14218162570421 0.356657209729256 FYN/CASP8/EEF1B2/STAT3/ACTR2 5 GO:0003170 heart valve development 3/376 65/18722 0.142202681040439 0.356657209729256 PRDM1/TGFB1/ROCK1 3 GO:0038034 signal transduction in absence of ligand 3/376 65/18722 0.142202681040439 0.356657209729256 FYN/TNF/MCL1 3 GO:0045453 bone resorption 3/376 65/18722 0.142202681040439 0.356657209729256 RAC2/TNFAIP3/CSK 3 GO:0045682 regulation of epidermis development 3/376 65/18722 0.142202681040439 0.356657209729256 ZFP36/PRKCH/ROCK1 3 GO:0048524 positive regulation of viral process 3/376 65/18722 0.142202681040439 0.356657209729256 CCL5/LGALS1/PABPC1 3 GO:0070613 regulation of protein processing 3/376 65/18722 0.142202681040439 0.356657209729256 CST7/PRKACB/CARD16 3 GO:0072577 endothelial cell apoptotic process 3/376 65/18722 0.142202681040439 0.356657209729256 TNF/ITGA4/TNFAIP3 3 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 3/376 65/18722 0.142202681040439 0.356657209729256 FYN/TNF/MCL1 3 GO:0062197 cellular response to chemical stress 10/376 337/18722 0.142703945084121 0.357682915395193 ETS1/KLF2/FYN/ATM/RCSD1/TNFAIP3/NR4A2/JUN/FOS/MCL1 10 GO:0030900 forebrain development 11/376 379/18722 0.14315465070155 0.358580653825795 B2M/ETS1/FYN/CXCR4/TYROBP/NR4A2/FLNA/ID2/SUN2/BTG2/ATRX 11 GO:0046626 regulation of insulin receptor signaling pathway 3/376 66/18722 0.146896696710564 0.367004964380036 PIP4K2A/PIK3R1/SORL1 3 GO:0050918 positive chemotaxis 3/376 66/18722 0.146896696710564 0.367004964380036 CCL5/CORO1A/CCL3 3 GO:0051893 regulation of focal adhesion assembly 3/376 66/18722 0.146896696710564 0.367004964380036 MACF1/ACTG1/ROCK1 3 GO:0090109 regulation of cell-substrate junction assembly 3/376 66/18722 0.146896696710564 0.367004964380036 MACF1/ACTG1/ROCK1 3 GO:0030216 keratinocyte differentiation 5/376 139/18722 0.148387303177353 0.368226230909367 TXNIP/STK4/ZFP36/PRKCH/ROCK1 5 GO:0002446 neutrophil mediated immunity 2/376 34/18722 0.148620858101226 0.368226230909367 ITGB2/KMT2E 2 GO:0007095 mitotic G2 DNA damage checkpoint signaling 2/376 34/18722 0.148620858101226 0.368226230909367 ATM/TAOK3 2 GO:0009303 rRNA transcription 2/376 34/18722 0.148620858101226 0.368226230909367 GTF3A/NCL 2 GO:0014072 response to isoquinoline alkaloid 2/376 34/18722 0.148620858101226 0.368226230909367 CXCR4/FOSB 2 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 2/376 34/18722 0.148620858101226 0.368226230909367 CALM1/CCL3 2 GO:0032743 positive regulation of interleukin-2 production 2/376 34/18722 0.148620858101226 0.368226230909367 PTPRC/CD3E 2 GO:0032770 positive regulation of monooxygenase activity 2/376 34/18722 0.148620858101226 0.368226230909367 TNF/CALM1 2 GO:0043278 response to morphine 2/376 34/18722 0.148620858101226 0.368226230909367 CXCR4/FOSB 2 GO:0044319 wound healing, spreading of cells 2/376 34/18722 0.148620858101226 0.368226230909367 CD44/FLNA 2 GO:0050931 pigment cell differentiation 2/376 34/18722 0.148620858101226 0.368226230909367 RAB27A/ZEB2 2 GO:0070884 regulation of calcineurin-NFAT signaling cascade 2/376 34/18722 0.148620858101226 0.368226230909367 TBC1D10C/TNF 2 GO:0090505 epiboly involved in wound healing 2/376 34/18722 0.148620858101226 0.368226230909367 CD44/FLNA 2 GO:0001841 neural tube formation 4/376 102/18722 0.149442151295345 0.370024496018826 STK4/TGFB1/PRKACB/PFN1 4 GO:0016445 somatic diversification of immunoglobulins 3/376 67/18722 0.151640617433786 0.374510766447367 PTPRC/TGFB1/SAMHD1 3 GO:0050435 amyloid-beta metabolic process 3/376 67/18722 0.151640617433786 0.374510766447367 TNF/SORL1/ROCK1 3 GO:1903317 regulation of protein maturation 3/376 67/18722 0.151640617433786 0.374510766447367 CST7/PRKACB/CARD16 3 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 3/376 67/18722 0.151640617433786 0.374510766447367 XCL1/RUNX3/CD81 3 GO:0045927 positive regulation of growth 8/376 259/18722 0.151761105603347 0.374569607778962 HOPX/CYBA/CXCR4/SEMA4D/RPS6KA3/PIM1/CDC42/MACF1 8 GO:1901991 negative regulation of mitotic cell cycle phase transition 6/376 179/18722 0.152267561969585 0.375580396328545 ZFP36L2/ATM/RBL2/DUSP1/TAOK3/PRMT2 6 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 4/376 103/18722 0.153191211415154 0.377618285135955 CCL5/PTPRC/TNF/IL10RA 4 GO:0016571 histone methylation 5/376 141/18722 0.154706111025 0.38003844893424 KMT2A/KMT2E/MLLT6/PRMT2/ATRX 5 GO:0048284 organelle fusion 5/376 141/18722 0.154706111025 0.38003844893424 CORO1A/PIP4K2A/SAMD9/RAB8B/VAMP2 5 GO:0001893 maternal placenta development 2/376 35/18722 0.155644133795778 0.38003844893424 PRDM1/JUNB 2 GO:0003351 epithelial cilium movement involved in extracellular fluid movement 2/376 35/18722 0.155644133795778 0.38003844893424 OFD1/SLC9A3R1 2 GO:0008608 attachment of spindle microtubules to kinetochore 2/376 35/18722 0.155644133795778 0.38003844893424 CDC42/CENPC 2 GO:0032205 negative regulation of telomere maintenance 2/376 35/18722 0.155644133795778 0.38003844893424 ATM/TERF2IP 2 GO:0033280 response to vitamin D 2/376 35/18722 0.155644133795778 0.38003844893424 CDKN2D/PIM1 2 GO:0034405 response to fluid shear stress 2/376 35/18722 0.155644133795778 0.38003844893424 ETS1/KLF2 2 GO:0043243 positive regulation of protein-containing complex disassembly 2/376 35/18722 0.155644133795778 0.38003844893424 PLEK/TNF 2 GO:0048821 erythrocyte development 2/376 35/18722 0.155644133795778 0.38003844893424 KLF2/LYAR 2 GO:0070536 protein K63-linked deubiquitination 2/376 35/18722 0.155644133795778 0.38003844893424 TNFAIP3/CYLD 2 GO:0090504 epiboly 2/376 35/18722 0.155644133795778 0.38003844893424 CD44/FLNA 2 GO:0106056 regulation of calcineurin-mediated signaling 2/376 35/18722 0.155644133795778 0.38003844893424 TBC1D10C/TNF 2 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 2/376 35/18722 0.155644133795778 0.38003844893424 CALM1/CCL3 2 GO:1905898 positive regulation of response to endoplasmic reticulum stress 2/376 35/18722 0.155644133795778 0.38003844893424 PIK3R1/XBP1 2 GO:0007585 respiratory gaseous exchange by respiratory system 3/376 68/18722 0.156432733410406 0.380048176780766 NR4A2/YWHAZ/GLS 3 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 3/376 68/18722 0.156432733410406 0.380048176780766 TMSB4X/TGFB1/STAT3 3 GO:0009988 cell-cell recognition 3/376 68/18722 0.156432733410406 0.380048176780766 PRF1/MSN/CD81 3 GO:0031640 killing of cells of other organism 3/376 68/18722 0.156432733410406 0.380048176780766 GNLY/PRF1/RPL30 3 GO:0032922 circadian regulation of gene expression 3/376 68/18722 0.156432733410406 0.380048176780766 RORA/ID2/KMT2A 3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 3/376 68/18722 0.156432733410406 0.380048176780766 CCL5/FYN/TNF 3 GO:0042987 amyloid precursor protein catabolic process 3/376 68/18722 0.156432733410406 0.380048176780766 TNF/SORL1/ROCK1 3 GO:0046686 response to cadmium ion 3/376 68/18722 0.156432733410406 0.380048176780766 B2M/JUN/FOS 3 GO:0008361 regulation of cell size 6/376 181/18722 0.157857229028297 0.383028655281559 IL7R/PLEK/MSN/SEMA4D/SLC9A3R1/MACF1 6 GO:0099504 synaptic vesicle cycle 6/376 181/18722 0.157857229028297 0.383028655281559 CALM1/ACTB/VAMP2/RAP1B/ACTG1/ROCK1 6 GO:0031330 negative regulation of cellular catabolic process 8/376 262/18722 0.15864347870815 0.384695544426835 PTPN22/ZFP36/IL10RA/PABPC1/SORL1/STAT3/MCL1/ROCK1 8 GO:0062207 regulation of pattern recognition receptor signaling pathway 4/376 105/18722 0.160794518536883 0.389667766935849 PTPN22/CYBA/IRF1/TNFAIP3 4 GO:0009145 purine nucleoside triphosphate biosynthetic process 3/376 69/18722 0.161271339564796 0.390091411244435 TMSB4X/TGFB1/STAT3 3 GO:0045669 positive regulation of osteoblast differentiation 3/376 69/18722 0.161271339564796 0.390091411244435 IFITM1/JUND/CLIC1 3 GO:1901224 positive regulation of NIK/NF-kappaB signaling 3/376 69/18722 0.161271339564796 0.390091411244435 TNF/LAPTM5/TERF2IP 3 GO:0030224 monocyte differentiation 2/376 36/18722 0.162729278978181 0.391662084497175 IFI16/JUN 2 GO:0038179 neurotrophin signaling pathway 2/376 36/18722 0.162729278978181 0.391662084497175 CORO1A/DDIT4 2 GO:0042092 type 2 immune response 2/376 36/18722 0.162729278978181 0.391662084497175 XCL1/CD81 2 GO:0045191 regulation of isotype switching 2/376 36/18722 0.162729278978181 0.391662084497175 PTPRC/TGFB1 2 GO:0060251 regulation of glial cell proliferation 2/376 36/18722 0.162729278978181 0.391662084497175 TNF/PRKCH 2 GO:0090313 regulation of protein targeting to membrane 2/376 36/18722 0.162729278978181 0.391662084497175 FYN/ITGB2 2 GO:1901658 glycosyl compound catabolic process 2/376 36/18722 0.162729278978181 0.391662084497175 APOBEC3G/APOBEC3C 2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/376 36/18722 0.162729278978181 0.391662084497175 CDKN2D/CD44 2 GO:0001890 placenta development 5/376 144/18722 0.164389044499895 0.395165972355517 EOMES/PRDM1/STK4/JUNB/CASP8 5 GO:0007612 learning 5/376 144/18722 0.164389044499895 0.395165972355517 FYN/JUN/FOS/BTG2/ACTR2 5 GO:0071887 leukocyte apoptotic process 4/376 106/18722 0.164647213773515 0.395541198618952 CCL5/IL7R/TSC22D3/CD3G 4 GO:0010001 glial cell differentiation 7/376 225/18722 0.168233620640947 0.403656520113728 TNF/CXCR4/VIM/TGFB1/ID2/CSK/STAT3 7 GO:0016485 protein processing 7/376 225/18722 0.168233620640947 0.403656520113728 CST7/SRGN/IFI16/PRKACB/CASP8/CARD16/PYCARD 7 GO:0051341 regulation of oxidoreductase activity 4/376 107/18722 0.168532893396165 0.404124357617661 GZMA/CYBA/TNF/CALM1 4 GO:0007369 gastrulation 6/376 185/18722 0.16929990057952 0.405326422395762 DUSP2/MBP/EOMES/ITGB2/ITGA4/DUSP1 6 GO:0003016 respiratory system process 2/376 37/18722 0.169870996121476 0.405326422395762 YWHAZ/GLS 2 GO:0003176 aortic valve development 2/376 37/18722 0.169870996121476 0.405326422395762 TGFB1/ROCK1 2 GO:0006904 vesicle docking involved in exocytosis 2/376 37/18722 0.169870996121476 0.405326422395762 PLEK/RAB8B 2 GO:0033363 secretory granule organization 2/376 37/18722 0.169870996121476 0.405326422395762 SRGN/LYST 2 GO:0043029 T cell homeostasis 2/376 37/18722 0.169870996121476 0.405326422395762 TSC22D3/CORO1A 2 GO:0060428 lung epithelium development 2/376 37/18722 0.169870996121476 0.405326422395762 KLF2/CDC42 2 GO:0072529 pyrimidine-containing compound catabolic process 2/376 37/18722 0.169870996121476 0.405326422395762 APOBEC3G/APOBEC3C 2 GO:0048813 dendrite morphogenesis 5/376 146/18722 0.170975738308724 0.407711375966957 FYN/CFL1/SEMA4D/CDC42/ACTR2 5 GO:0032722 positive regulation of chemokine production 3/376 71/18722 0.171081233834516 0.407712042502307 MBP/TNF/PYCARD 3 GO:0034446 substrate adhesion-dependent cell spreading 4/376 108/18722 0.172450769028459 0.410723251373864 ITGA4/FLNA/PIK3R1/CDC42 4 GO:0001894 tissue homeostasis 8/376 268/18722 0.172839191288856 0.411395495236067 B2M/RAC2/CORO1A/MBP/TNFAIP3/ACTB/CSK/ACTG1 8 GO:0033044 regulation of chromosome organization 6/376 187/18722 0.175148434949951 0.416636086820785 ATM/DUSP1/TERF2IP/MPHOSPH8/ATRX/ATF7IP 6 GO:0001825 blastocyst formation 2/376 38/18722 0.177064174482909 0.418368095195899 HOPX/JUNB 2 GO:0002385 mucosal immune response 2/376 38/18722 0.177064174482909 0.418368095195899 XCL1/RPL39 2 GO:0006858 extracellular transport 2/376 38/18722 0.177064174482909 0.418368095195899 OFD1/SLC9A3R1 2 GO:0007094 mitotic spindle assembly checkpoint signaling 2/376 38/18722 0.177064174482909 0.418368095195899 ATM/DUSP1 2 GO:0009595 detection of biotic stimulus 2/376 38/18722 0.177064174482909 0.418368095195899 HLA-A/HLA-B 2 GO:0030279 negative regulation of ossification 2/376 38/18722 0.177064174482909 0.418368095195899 SRGN/CCL3 2 GO:0032717 negative regulation of interleukin-8 production 2/376 38/18722 0.177064174482909 0.418368095195899 TMSB4X/PTPN22 2 GO:0071173 spindle assembly checkpoint signaling 2/376 38/18722 0.177064174482909 0.418368095195899 ATM/DUSP1 2 GO:0071174 mitotic spindle checkpoint signaling 2/376 38/18722 0.177064174482909 0.418368095195899 ATM/DUSP1 2 GO:0072538 T-helper 17 type immune response 2/376 38/18722 0.177064174482909 0.418368095195899 RORA/STAT3 2 GO:1903580 positive regulation of ATP metabolic process 2/376 38/18722 0.177064174482909 0.418368095195899 TMSB4X/STAT3 2 GO:0035148 tube formation 5/376 148/18722 0.177663391158925 0.419514836466413 STK4/TGFB1/PRKACB/PFN1/YWHAZ 5 GO:0070588 calcium ion transmembrane transport 9/376 312/18722 0.177766028768477 0.419514836466413 PTPRC/XCL1/CORO1A/FYN/LCK/CYBA/CALM1/CCL3/PTPN6 9 GO:0030308 negative regulation of cell growth 6/376 188/18722 0.178103494139467 0.419857468248272 BTG1/BST2/TGFB1/CDKN2D/SEMA4D/CCDC85B 6 GO:0003014 renal system process 4/376 110/18722 0.180379935295609 0.419857468248272 CYBA/PRKACB/SLC9A3R1/MLLT6 4 GO:0045834 positive regulation of lipid metabolic process 5/376 149/18722 0.18104393945296 0.419857468248272 TNF/TGFB1/DGKZ/CDC42/CD81 5 GO:0072089 stem cell proliferation 3/376 73/18722 0.18105680413201 0.419857468248272 PTPRC/N4BP2L2/PIM1 3 GO:0051962 positive regulation of nervous system development 8/376 272/18722 0.182609987316209 0.419857468248272 TNF/CXCR4/TGFB1/ID2/SEMA4D/PRKCH/MACF1/ACTR2 8 GO:0022411 cellular component disassembly 12/376 443/18722 0.182646330364555 0.419857468248272 ETS1/LCP1/PLEK/TNF/CALM1/DDIT4/TGFB1/CFL1/TOMM7/PIK3R1/KIF2A/VPS13C 12 GO:0001865 NK T cell differentiation 1/376 10/18722 0.183661871642727 0.419857468248272 PRDM1 1 GO:0002084 protein depalmitoylation 1/376 10/18722 0.183661871642727 0.419857468248272 ABHD17A 1 GO:0002524 hypersensitivity 1/376 10/18722 0.183661871642727 0.419857468248272 HLA-E 1 GO:0002765 immune response-inhibiting signal transduction 1/376 10/18722 0.183661871642727 0.419857468248272 KLRC1 1 GO:0009113 purine nucleobase biosynthetic process 1/376 10/18722 0.183661871642727 0.419857468248272 APRT 1 GO:0009133 nucleoside diphosphate biosynthetic process 1/376 10/18722 0.183661871642727 0.419857468248272 GUK1 1 GO:0009170 purine deoxyribonucleoside monophosphate metabolic process 1/376 10/18722 0.183661871642727 0.419857468248272 GUK1 1 GO:0009750 response to fructose 1/376 10/18722 0.183661871642727 0.419857468248272 XBP1 1 GO:0019062 virion attachment to host cell 1/376 10/18722 0.183661871642727 0.419857468248272 CD81 1 GO:0021932 hindbrain radial glia guided cell migration 1/376 10/18722 0.183661871642727 0.419857468248272 FLNA 1 GO:0031848 protection from non-homologous end joining at telomere 1/376 10/18722 0.183661871642727 0.419857468248272 TERF2IP 1 GO:0032025 response to cobalt ion 1/376 10/18722 0.183661871642727 0.419857468248272 CASP8 1 GO:0032070 regulation of deoxyribonuclease activity 1/376 10/18722 0.183661871642727 0.419857468248272 GZMA 1 GO:0034756 regulation of iron ion transport 1/376 10/18722 0.183661871642727 0.419857468248272 B2M 1 GO:0035871 protein K11-linked deubiquitination 1/376 10/18722 0.183661871642727 0.419857468248272 TNFAIP3 1 GO:0040015 negative regulation of multicellular organism growth 1/376 10/18722 0.183661871642727 0.419857468248272 PLAC8 1 GO:0042368 vitamin D biosynthetic process 1/376 10/18722 0.183661871642727 0.419857468248272 TNF 1 GO:0042996 regulation of Golgi to plasma membrane protein transport 1/376 10/18722 0.183661871642727 0.419857468248272 CSK 1 GO:0043101 purine-containing compound salvage 1/376 10/18722 0.183661871642727 0.419857468248272 APRT 1 GO:0044351 macropinocytosis 1/376 10/18722 0.183661871642727 0.419857468248272 PYCARD 1 GO:0045348 positive regulation of MHC class II biosynthetic process 1/376 10/18722 0.183661871642727 0.419857468248272 XBP1 1 GO:0045843 negative regulation of striated muscle tissue development 1/376 10/18722 0.183661871642727 0.419857468248272 TGFB1 1 GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly 1/376 10/18722 0.183661871642727 0.419857468248272 ATF7IP 1 GO:0048672 positive regulation of collateral sprouting 1/376 10/18722 0.183661871642727 0.419857468248272 SEMA4D 1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1/376 10/18722 0.183661871642727 0.419857468248272 CALM1 1 GO:0051351 positive regulation of ligase activity 1/376 10/18722 0.183661871642727 0.419857468248272 TMSB4X 1 GO:0051409 response to nitrosative stress 1/376 10/18722 0.183661871642727 0.419857468248272 ATM 1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1/376 10/18722 0.183661871642727 0.419857468248272 UCP2 1 GO:0070099 regulation of chemokine-mediated signaling pathway 1/376 10/18722 0.183661871642727 0.419857468248272 CCL5 1 GO:0070561 vitamin D receptor signaling pathway 1/376 10/18722 0.183661871642727 0.419857468248272 PIM1 1 GO:0072124 regulation of glomerular mesangial cell proliferation 1/376 10/18722 0.183661871642727 0.419857468248272 CFLAR 1 GO:0072203 cell proliferation involved in metanephros development 1/376 10/18722 0.183661871642727 0.419857468248272 STAT1 1 GO:0090209 negative regulation of triglyceride metabolic process 1/376 10/18722 0.183661871642727 0.419857468248272 SORL1 1 GO:0090647 modulation of age-related behavioral decline 1/376 10/18722 0.183661871642727 0.419857468248272 B2M 1 GO:0097278 complement-dependent cytotoxicity 1/376 10/18722 0.183661871642727 0.419857468248272 RAB27A 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/376 10/18722 0.183661871642727 0.419857468248272 PFN1 1 GO:0098903 regulation of membrane repolarization during action potential 1/376 10/18722 0.183661871642727 0.419857468248272 FLNA 1 GO:1901203 positive regulation of extracellular matrix assembly 1/376 10/18722 0.183661871642727 0.419857468248272 TGFB1 1 GO:1901524 regulation of mitophagy 1/376 10/18722 0.183661871642727 0.419857468248272 VPS13C 1 GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 1/376 10/18722 0.183661871642727 0.419857468248272 NCL 1 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 1/376 10/18722 0.183661871642727 0.419857468248272 SORL1 1 GO:1903980 positive regulation of microglial cell activation 1/376 10/18722 0.183661871642727 0.419857468248272 CCL3 1 GO:1904350 regulation of protein catabolic process in the vacuole 1/376 10/18722 0.183661871642727 0.419857468248272 CD81 1 GO:2000288 positive regulation of myoblast proliferation 1/376 10/18722 0.183661871642727 0.419857468248272 MALAT1 1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation 1/376 10/18722 0.183661871642727 0.419857468248272 WAS 1 GO:2001223 negative regulation of neuron migration 1/376 10/18722 0.183661871642727 0.419857468248272 STAT3 1 GO:0016233 telomere capping 2/376 39/18722 0.184303884771693 0.419857468248272 ATM/TERF2IP 2 GO:0031507 heterochromatin assembly 2/376 39/18722 0.184303884771693 0.419857468248272 MPHOSPH8/ATF7IP 2 GO:0031577 spindle checkpoint signaling 2/376 39/18722 0.184303884771693 0.419857468248272 ATM/DUSP1 2 GO:0032728 positive regulation of interferon-beta production 2/376 39/18722 0.184303884771693 0.419857468248272 IRF1/ISG15 2 GO:0042417 dopamine metabolic process 2/376 39/18722 0.184303884771693 0.419857468248272 ITGB2/NR4A2 2 GO:0071548 response to dexamethasone 2/376 39/18722 0.184303884771693 0.419857468248272 DDIT4/CFLAR 2 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 2/376 39/18722 0.184303884771693 0.419857468248272 XCL1/CD81 2 GO:0009201 ribonucleoside triphosphate biosynthetic process 3/376 74/18722 0.186102541816879 0.422960322311088 TMSB4X/TGFB1/STAT3 3 GO:0030968 endoplasmic reticulum unfolded protein response 3/376 74/18722 0.186102541816879 0.422960322311088 PIK3R1/XBP1/PPP1R15A 3 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 3/376 74/18722 0.186102541816879 0.422960322311088 DDX5/LBH/PRMT2 3 GO:0046323 glucose import 3/376 74/18722 0.186102541816879 0.422960322311088 TNF/SLC2A3/PIK3R1 3 GO:0071456 cellular response to hypoxia 5/376 151/18722 0.187876169705677 0.426741006805099 MALAT1/RORA/CARD16/CFLAR/HP1BP3 5 GO:0002526 acute inflammatory response 4/376 112/18722 0.188428334796349 0.427494026543239 HLA-E/ALOX5AP/TNF/STAT3 4 GO:0010633 negative regulation of epithelial cell migration 4/376 112/18722 0.188428334796349 0.427494026543239 EVL/TNF/TGFB1/SP100 4 GO:0009394 2'-deoxyribonucleotide metabolic process 2/376 40/18722 0.191585373954677 0.428790647096672 SAMHD1/GUK1 2 GO:0030501 positive regulation of bone mineralization 2/376 40/18722 0.191585373954677 0.428790647096672 TGFB1/ISG15 2 GO:0031297 replication fork processing 2/376 40/18722 0.191585373954677 0.428790647096672 SAMHD1/ATRX 2 GO:0045022 early endosome to late endosome transport 2/376 40/18722 0.191585373954677 0.428790647096672 MSN/FLNA 2 GO:0045429 positive regulation of nitric oxide biosynthetic process 2/376 40/18722 0.191585373954677 0.428790647096672 KLF2/TNF 2 GO:0045777 positive regulation of blood pressure 2/376 40/18722 0.191585373954677 0.428790647096672 CYBA/ID2 2 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 2/376 40/18722 0.191585373954677 0.428790647096672 ATM/DUSP1 2 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 2/376 40/18722 0.191585373954677 0.428790647096672 XCL1/CALM1 2 GO:0055081 anion homeostasis 2/376 40/18722 0.191585373954677 0.428790647096672 GLS/SLC9A3R1 2 GO:0071276 cellular response to cadmium ion 2/376 40/18722 0.191585373954677 0.428790647096672 JUN/FOS 2 GO:0071526 semaphorin-plexin signaling pathway 2/376 40/18722 0.191585373954677 0.428790647096672 FLNA/SEMA4D 2 GO:2000142 regulation of DNA-templated transcription, initiation 2/376 40/18722 0.191585373954677 0.428790647096672 JUN/ATF7IP 2 GO:2000781 positive regulation of double-strand break repair 2/376 40/18722 0.191585373954677 0.428790647096672 WAS/ACTR2 2 GO:0044344 cellular response to fibroblast growth factor stimulus 4/376 113/18722 0.192495242727973 0.428790647096672 CCL5/ZFP36L2/CD44/ZFP36 4 GO:0006809 nitric oxide biosynthetic process 3/376 76/18722 0.196301670385838 0.428790647096672 KLF2/RORA/TNF 3 GO:0014855 striated muscle cell proliferation 3/376 76/18722 0.196301670385838 0.428790647096672 PIM1/STAT3/CFLAR 3 GO:0032720 negative regulation of tumor necrosis factor production 3/376 76/18722 0.196301670385838 0.428790647096672 PTPN22/TNFAIP3/PTPN6 3 GO:0043536 positive regulation of blood vessel endothelial cell migration 3/376 76/18722 0.196301670385838 0.428790647096672 TMSB4X/ETS1/TGFB1 3 GO:0045685 regulation of glial cell differentiation 3/376 76/18722 0.196301670385838 0.428790647096672 CXCR4/TGFB1/ID2 3 GO:0050767 regulation of neurogenesis 10/376 364/18722 0.19855828653624 0.428790647096672 B2M/TNF/CXCR4/TGFB1/ID2/SEMA4D/PRKCH/SORL1/MACF1/ACTR2 10 GO:0002251 organ or tissue specific immune response 2/376 41/18722 0.198904060196587 0.428790647096672 XCL1/RPL39 2 GO:0009167 purine ribonucleoside monophosphate metabolic process 2/376 41/18722 0.198904060196587 0.428790647096672 GUK1/APRT 2 GO:0031062 positive regulation of histone methylation 2/376 41/18722 0.198904060196587 0.428790647096672 KMT2A/KMT2E 2 GO:0060612 adipose tissue development 2/376 41/18722 0.198904060196587 0.428790647096672 XBP1/SORL1 2 GO:0070296 sarcoplasmic reticulum calcium ion transport 2/376 41/18722 0.198904060196587 0.428790647096672 CALM1/CCL3 2 GO:0071634 regulation of transforming growth factor beta production 2/376 41/18722 0.198904060196587 0.428790647096672 XCL1/TYROBP 2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 2/376 41/18722 0.198904060196587 0.428790647096672 FLNA/CDC42 2 GO:1900371 regulation of purine nucleotide biosynthetic process 2/376 41/18722 0.198904060196587 0.428790647096672 TMSB4X/STAT3 2 GO:1904407 positive regulation of nitric oxide metabolic process 2/376 41/18722 0.198904060196587 0.428790647096672 KLF2/TNF 2 GO:1905314 semi-lunar valve development 2/376 41/18722 0.198904060196587 0.428790647096672 TGFB1/ROCK1 2 GO:0001660 fever generation 1/376 11/18722 0.200065416761492 0.428790647096672 TNF 1 GO:0001967 suckling behavior 1/376 11/18722 0.200065416761492 0.428790647096672 GLS 1 GO:0002327 immature B cell differentiation 1/376 11/18722 0.200065416761492 0.428790647096672 ATM 1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1/376 11/18722 0.200065416761492 0.428790647096672 PTPN6 1 GO:0003093 regulation of glomerular filtration 1/376 11/18722 0.200065416761492 0.428790647096672 CYBA 1 GO:0003157 endocardium development 1/376 11/18722 0.200065416761492 0.428790647096672 STK4 1 GO:0003263 cardioblast proliferation 1/376 11/18722 0.200065416761492 0.428790647096672 PIM1 1 GO:0003264 regulation of cardioblast proliferation 1/376 11/18722 0.200065416761492 0.428790647096672 PIM1 1 GO:0006188 IMP biosynthetic process 1/376 11/18722 0.200065416761492 0.428790647096672 APRT 1 GO:0009155 purine deoxyribonucleotide catabolic process 1/376 11/18722 0.200065416761492 0.428790647096672 SAMHD1 1 GO:0019372 lipoxygenase pathway 1/376 11/18722 0.200065416761492 0.428790647096672 ALOX5AP 1 GO:0021702 cerebellar Purkinje cell differentiation 1/376 11/18722 0.200065416761492 0.428790647096672 RORA 1 GO:0030656 regulation of vitamin metabolic process 1/376 11/18722 0.200065416761492 0.428790647096672 TNF 1 GO:0031652 positive regulation of heat generation 1/376 11/18722 0.200065416761492 0.428790647096672 TNF 1 GO:0033210 leptin-mediated signaling pathway 1/376 11/18722 0.200065416761492 0.428790647096672 STAT3 1 GO:0033327 Leydig cell differentiation 1/376 11/18722 0.200065416761492 0.428790647096672 SF1 1 GO:0033860 regulation of NAD(P)H oxidase activity 1/376 11/18722 0.200065416761492 0.428790647096672 CYBA 1 GO:0034115 negative regulation of heterotypic cell-cell adhesion 1/376 11/18722 0.200065416761492 0.428790647096672 MBP 1 GO:0034163 regulation of toll-like receptor 9 signaling pathway 1/376 11/18722 0.200065416761492 0.428790647096672 PTPN22 1 GO:0034350 regulation of glial cell apoptotic process 1/376 11/18722 0.200065416761492 0.428790647096672 PRKCH 1 GO:0034969 histone arginine methylation 1/376 11/18722 0.200065416761492 0.428790647096672 PRMT2 1 GO:0035090 maintenance of apical/basal cell polarity 1/376 11/18722 0.200065416761492 0.428790647096672 SLC9A3R1 1 GO:0035246 peptidyl-arginine N-methylation 1/376 11/18722 0.200065416761492 0.428790647096672 PRMT2 1 GO:0035457 cellular response to interferon-alpha 1/376 11/18722 0.200065416761492 0.428790647096672 PYHIN1 1 GO:0036490 regulation of translation in response to endoplasmic reticulum stress 1/376 11/18722 0.200065416761492 0.428790647096672 PPP1R15A 1 GO:0042416 dopamine biosynthetic process 1/376 11/18722 0.200065416761492 0.428790647096672 NR4A2 1 GO:0042451 purine nucleoside biosynthetic process 1/376 11/18722 0.200065416761492 0.428790647096672 APRT 1 GO:0042455 ribonucleoside biosynthetic process 1/376 11/18722 0.200065416761492 0.428790647096672 APRT 1 GO:0043312 neutrophil degranulation 1/376 11/18722 0.200065416761492 0.428790647096672 ITGB2 1 GO:0045199 maintenance of epithelial cell apical/basal polarity 1/376 11/18722 0.200065416761492 0.428790647096672 SLC9A3R1 1 GO:0045657 positive regulation of monocyte differentiation 1/376 11/18722 0.200065416761492 0.428790647096672 JUN 1 GO:0046129 purine ribonucleoside biosynthetic process 1/376 11/18722 0.200065416761492 0.428790647096672 APRT 1 GO:0046598 positive regulation of viral entry into host cell 1/376 11/18722 0.200065416761492 0.428790647096672 LGALS1 1 GO:0046643 regulation of gamma-delta T cell activation 1/376 11/18722 0.200065416761492 0.428790647096672 PTPRC 1 GO:0046710 GDP metabolic process 1/376 11/18722 0.200065416761492 0.428790647096672 GUK1 1 GO:0046929 negative regulation of neurotransmitter secretion 1/376 11/18722 0.200065416761492 0.428790647096672 RAP1B 1 GO:0048635 negative regulation of muscle organ development 1/376 11/18722 0.200065416761492 0.428790647096672 TGFB1 1 GO:0048680 positive regulation of axon regeneration 1/376 11/18722 0.200065416761492 0.428790647096672 FLNA 1 GO:0051798 positive regulation of hair follicle development 1/376 11/18722 0.200065416761492 0.428790647096672 TNF 1 GO:0060312 regulation of blood vessel remodeling 1/376 11/18722 0.200065416761492 0.428790647096672 TGFB1 1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 1/376 11/18722 0.200065416761492 0.428790647096672 CALM1 1 GO:0061635 regulation of protein complex stability 1/376 11/18722 0.200065416761492 0.428790647096672 TAPBP 1 GO:0070417 cellular response to cold 1/376 11/18722 0.200065416761492 0.428790647096672 NFKBIA 1 GO:0070587 regulation of cell-cell adhesion involved in gastrulation 1/376 11/18722 0.200065416761492 0.428790647096672 MBP 1 GO:0071044 histone mRNA catabolic process 1/376 11/18722 0.200065416761492 0.428790647096672 ATM 1 GO:0072110 glomerular mesangial cell proliferation 1/376 11/18722 0.200065416761492 0.428790647096672 CFLAR 1 GO:0072697 protein localization to cell cortex 1/376 11/18722 0.200065416761492 0.428790647096672 EPB41 1 GO:0075294 positive regulation by symbiont of entry into host 1/376 11/18722 0.200065416761492 0.428790647096672 LGALS1 1 GO:0075733 intracellular transport of virus 1/376 11/18722 0.200065416761492 0.428790647096672 BST2 1 GO:0090084 negative regulation of inclusion body assembly 1/376 11/18722 0.200065416761492 0.428790647096672 SORL1 1 GO:0090160 Golgi to lysosome transport 1/376 11/18722 0.200065416761492 0.428790647096672 LAPTM5 1 GO:0090219 negative regulation of lipid kinase activity 1/376 11/18722 0.200065416761492 0.428790647096672 PIP4K2A 1 GO:0090660 cerebrospinal fluid circulation 1/376 11/18722 0.200065416761492 0.428790647096672 SLC9A3R1 1 GO:0099624 atrial cardiac muscle cell membrane repolarization 1/376 11/18722 0.200065416761492 0.428790647096672 FLNA 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/376 11/18722 0.200065416761492 0.428790647096672 ATRX 1 GO:1900222 negative regulation of amyloid-beta clearance 1/376 11/18722 0.200065416761492 0.428790647096672 TNF 1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly 1/376 11/18722 0.200065416761492 0.428790647096672 GBP5 1 GO:1900426 positive regulation of defense response to bacterium 1/376 11/18722 0.200065416761492 0.428790647096672 CYBA 1 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/376 11/18722 0.200065416761492 0.428790647096672 GZMB 1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation 1/376 11/18722 0.200065416761492 0.428790647096672 N4BP2L2 1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 1/376 11/18722 0.200065416761492 0.428790647096672 CALM1 1 GO:1901862 negative regulation of muscle tissue development 1/376 11/18722 0.200065416761492 0.428790647096672 TGFB1 1 GO:1902065 response to L-glutamate 1/376 11/18722 0.200065416761492 0.428790647096672 FYN 1 GO:1903238 positive regulation of leukocyte tethering or rolling 1/376 11/18722 0.200065416761492 0.428790647096672 ITGA4 1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 1/376 11/18722 0.200065416761492 0.428790647096672 LAPTM5 1 GO:1903897 regulation of PERK-mediated unfolded protein response 1/376 11/18722 0.200065416761492 0.428790647096672 PPP1R15A 1 GO:2000392 regulation of lamellipodium morphogenesis 1/376 11/18722 0.200065416761492 0.428790647096672 CD44 1 GO:2000615 regulation of histone H3-K9 acetylation 1/376 11/18722 0.200065416761492 0.428790647096672 KMT2A 1 GO:2000644 regulation of receptor catabolic process 1/376 11/18722 0.200065416761492 0.428790647096672 LAPTM5 1 GO:2000786 positive regulation of autophagosome assembly 1/376 11/18722 0.200065416761492 0.428790647096672 PIP4K2A 1 GO:0034968 histone lysine methylation 4/376 115/18722 0.200710451637568 0.429935323435919 KMT2A/KMT2E/MLLT6/ATRX 4 GO:0002200 somatic diversification of immune receptors 3/376 77/18722 0.201451799502945 0.43080889794366 PTPRC/TGFB1/SAMHD1 3 GO:0032418 lysosome localization 3/376 77/18722 0.201451799502945 0.43080889794366 RAC2/RASGRP1/LAT 3 GO:0140056 organelle localization by membrane tethering 3/376 77/18722 0.201451799502945 0.43080889794366 PLEK/CALM1/RAB8B 3 GO:0034614 cellular response to reactive oxygen species 5/376 155/18722 0.201812013123628 0.431320225945495 ETS1/KLF2/TNFAIP3/JUN/FOS 5 GO:0006325 chromatin organization 11/376 409/18722 0.201913519965194 0.431320225945495 IKZF1/RBL2/ACTB/KMT2E/ANP32E/ARID4B/MPHOSPH8/ATRX/CHD9/ATF7IP/HP1BP3 11 GO:0030518 intracellular steroid hormone receptor signaling pathway 4/376 116/18722 0.204857140475662 0.436982050702387 DDX5/LBH/PRMT2/DDX17 4 GO:0043200 response to amino acid 4/376 116/18722 0.204857140475662 0.436982050702387 FYN/CYBA/TNF/XBP1 4 GO:0019692 deoxyribose phosphate metabolic process 2/376 42/18722 0.206255527931527 0.436982050702387 SAMHD1/GUK1 2 GO:0030808 regulation of nucleotide biosynthetic process 2/376 42/18722 0.206255527931527 0.436982050702387 TMSB4X/STAT3 2 GO:0030890 positive regulation of B cell proliferation 2/376 42/18722 0.206255527931527 0.436982050702387 PTPRC/CD81 2 GO:0032691 negative regulation of interleukin-1 beta production 2/376 42/18722 0.206255527931527 0.436982050702387 TNFAIP3/CARD16 2 GO:0032965 regulation of collagen biosynthetic process 2/376 42/18722 0.206255527931527 0.436982050702387 VIM/TGFB1 2 GO:0035019 somatic stem cell population maintenance 2/376 42/18722 0.206255527931527 0.436982050702387 ZFP36L2/LBH 2 GO:0043507 positive regulation of JUN kinase activity 2/376 42/18722 0.206255527931527 0.436982050702387 TNF/TAOK3 2 GO:0045214 sarcomere organization 2/376 42/18722 0.206255527931527 0.436982050702387 AKAP13/ACTG1 2 GO:0055090 acylglycerol homeostasis 2/376 42/18722 0.206255527931527 0.436982050702387 RORA/XBP1 2 GO:0070328 triglyceride homeostasis 2/376 42/18722 0.206255527931527 0.436982050702387 RORA/XBP1 2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic 2/376 42/18722 0.206255527931527 0.436982050702387 ISG20/CNOT6L 2 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 2/376 42/18722 0.206255527931527 0.436982050702387 ATM/DUSP1 2 GO:2001222 regulation of neuron migration 2/376 42/18722 0.206255527931527 0.436982050702387 FLNA/STAT3 2 GO:0008306 associative learning 3/376 78/18722 0.20663348772001 0.437065919713449 FOS/BTG2/ACTR2 3 GO:0090559 regulation of membrane permeability 3/376 78/18722 0.20663348772001 0.437065919713449 GZMB/LAPTM5/STAT3 3 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 3/376 78/18722 0.20663348772001 0.437065919713449 PTPN22/TNFAIP3/PTPN6 3 GO:0007030 Golgi organization 5/376 157/18722 0.208908006479273 0.438963995165783 SYNE1/RAB29/YWHAZ/CDC42/GCC2 5 GO:1990845 adaptive thermogenesis 5/376 157/18722 0.208908006479273 0.438963995165783 PLAC8/CXCR4/UCP2/SORL1/LNPEP 5 GO:0014902 myotube differentiation 4/376 117/18722 0.209028810293734 0.438963995165783 CD53/XBP1/CD81/CFLAR 4 GO:1903828 negative regulation of cellular protein localization 4/376 117/18722 0.209028810293734 0.438963995165783 TGFB1/SP100/ABHD17A/CSK 4 GO:0051146 striated muscle cell differentiation 8/376 283/18722 0.210656919324378 0.438963995165783 HOPX/CD53/TGFB1/XBP1/AKAP13/CD81/ACTG1/CFLAR 8 GO:0001895 retina homeostasis 3/376 79/18722 0.21184514095563 0.438963995165783 B2M/ACTB/ACTG1 3 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 3/376 79/18722 0.21184514095563 0.438963995165783 FLNA/CDC42/ACTR2 3 GO:0032272 negative regulation of protein polymerization 3/376 79/18722 0.21184514095563 0.438963995165783 TMSB4X/TMSB10/PFN1 3 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 3/376 79/18722 0.21184514095563 0.438963995165783 GNLY/RPL39/RPL30 3 GO:0001558 regulation of cell growth 11/376 414/18722 0.212620075283435 0.438963995165783 CYBA/BTG1/CXCR4/BST2/TGFB1/CDKN2D/SEMA4D/CCDC85B/RPS6KA3/CDC42/MACF1 11 GO:0030203 glycosaminoglycan metabolic process 4/376 118/18722 0.213224654896803 0.438963995165783 TGFB1/CD44/PIM1/CHST12 4 GO:0001709 cell fate determination 2/376 43/18722 0.213635523062544 0.438963995165783 CDC42/MCL1 2 GO:0006509 membrane protein ectodomain proteolysis 2/376 43/18722 0.213635523062544 0.438963995165783 TNF/ROCK1 2 GO:0014002 astrocyte development 2/376 43/18722 0.213635523062544 0.438963995165783 TNF/VIM 2 GO:0031952 regulation of protein autophosphorylation 2/376 43/18722 0.213635523062544 0.438963995165783 PTPRC/CALM1 2 GO:0033046 negative regulation of sister chromatid segregation 2/376 43/18722 0.213635523062544 0.438963995165783 ATM/DUSP1 2 GO:0033048 negative regulation of mitotic sister chromatid segregation 2/376 43/18722 0.213635523062544 0.438963995165783 ATM/DUSP1 2 GO:0033173 calcineurin-NFAT signaling cascade 2/376 43/18722 0.213635523062544 0.438963995165783 TBC1D10C/TNF 2 GO:0042088 T-helper 1 type immune response 2/376 43/18722 0.213635523062544 0.438963995165783 XCL1/SPN 2 GO:0045981 positive regulation of nucleotide metabolic process 2/376 43/18722 0.213635523062544 0.438963995165783 TMSB4X/STAT3 2 GO:0071604 transforming growth factor beta production 2/376 43/18722 0.213635523062544 0.438963995165783 XCL1/TYROBP 2 GO:1900544 positive regulation of purine nucleotide metabolic process 2/376 43/18722 0.213635523062544 0.438963995165783 TMSB4X/STAT3 2 GO:2000816 negative regulation of mitotic sister chromatid separation 2/376 43/18722 0.213635523062544 0.438963995165783 ATM/DUSP1 2 GO:0099003 vesicle-mediated transport in synapse 6/376 200/18722 0.215047094997191 0.438963995165783 CALM1/ACTB/VAMP2/RAP1B/ACTG1/ROCK1 6 GO:0002024 diet induced thermogenesis 1/376 12/18722 0.216140207168081 0.438963995165783 SORL1 1 GO:0002424 T cell mediated immune response to tumor cell 1/376 12/18722 0.216140207168081 0.438963995165783 HLA-A 1 GO:0008228 opsonization 1/376 12/18722 0.216140207168081 0.438963995165783 SPON2 1 GO:0009265 2'-deoxyribonucleotide biosynthetic process 1/376 12/18722 0.216140207168081 0.438963995165783 GUK1 1 GO:0009886 post-embryonic animal morphogenesis 1/376 12/18722 0.216140207168081 0.438963995165783 ATRX 1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 1/376 12/18722 0.216140207168081 0.438963995165783 SLC9A3R1 1 GO:0014889 muscle atrophy 1/376 12/18722 0.216140207168081 0.438963995165783 CFLAR 1 GO:0030238 male sex determination 1/376 12/18722 0.216140207168081 0.438963995165783 SF1 1 GO:0031953 negative regulation of protein autophosphorylation 1/376 12/18722 0.216140207168081 0.438963995165783 PTPRC 1 GO:0032621 interleukin-18 production 1/376 12/18722 0.216140207168081 0.438963995165783 GBP5 1 GO:0032661 regulation of interleukin-18 production 1/376 12/18722 0.216140207168081 0.438963995165783 GBP5 1 GO:0032736 positive regulation of interleukin-13 production 1/376 12/18722 0.216140207168081 0.438963995165783 HLA-E 1 GO:0032782 bile acid secretion 1/376 12/18722 0.216140207168081 0.438963995165783 SLC9A3R1 1 GO:0032908 regulation of transforming growth factor beta1 production 1/376 12/18722 0.216140207168081 0.438963995165783 TYROBP 1 GO:0034086 maintenance of sister chromatid cohesion 1/376 12/18722 0.216140207168081 0.438963995165783 ATRX 1 GO:0034088 maintenance of mitotic sister chromatid cohesion 1/376 12/18722 0.216140207168081 0.438963995165783 ATRX 1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 1/376 12/18722 0.216140207168081 0.438963995165783 PTPN22 1 GO:0034154 toll-like receptor 7 signaling pathway 1/376 12/18722 0.216140207168081 0.438963995165783 PTPN22 1 GO:0034333 adherens junction assembly 1/376 12/18722 0.216140207168081 0.438963995165783 ACTB 1 GO:0038180 nerve growth factor signaling pathway 1/376 12/18722 0.216140207168081 0.438963995165783 CORO1A 1 GO:0043301 negative regulation of leukocyte degranulation 1/376 12/18722 0.216140207168081 0.438963995165783 HLA-F 1 GO:0044650 adhesion of symbiont to host cell 1/376 12/18722 0.216140207168081 0.438963995165783 CD81 1 GO:0046385 deoxyribose phosphate biosynthetic process 1/376 12/18722 0.216140207168081 0.438963995165783 GUK1 1 GO:0048548 regulation of pinocytosis 1/376 12/18722 0.216140207168081 0.438963995165783 CDC42 1 GO:0048934 peripheral nervous system neuron differentiation 1/376 12/18722 0.216140207168081 0.438963995165783 RUNX3 1 GO:0048935 peripheral nervous system neuron development 1/376 12/18722 0.216140207168081 0.438963995165783 RUNX3 1 GO:0051340 regulation of ligase activity 1/376 12/18722 0.216140207168081 0.438963995165783 TMSB4X 1 GO:0051639 actin filament network formation 1/376 12/18722 0.216140207168081 0.438963995165783 LCP1 1 GO:0060019 radial glial cell differentiation 1/376 12/18722 0.216140207168081 0.438963995165783 STAT3 1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry 1/376 12/18722 0.216140207168081 0.438963995165783 OFD1 1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1/376 12/18722 0.216140207168081 0.438963995165783 PRKACB 1 GO:0061430 bone trabecula morphogenesis 1/376 12/18722 0.216140207168081 0.438963995165783 SEMA4D 1 GO:0070213 protein auto-ADP-ribosylation 1/376 12/18722 0.216140207168081 0.438963995165783 PARP8 1 GO:0070493 thrombin-activated receptor signaling pathway 1/376 12/18722 0.216140207168081 0.438963995165783 PLEK 1 GO:0070572 positive regulation of neuron projection regeneration 1/376 12/18722 0.216140207168081 0.438963995165783 FLNA 1 GO:0070586 cell-cell adhesion involved in gastrulation 1/376 12/18722 0.216140207168081 0.438963995165783 MBP 1 GO:0071635 negative regulation of transforming growth factor beta production 1/376 12/18722 0.216140207168081 0.438963995165783 TYROBP 1 GO:0072182 regulation of nephron tubule epithelial cell differentiation 1/376 12/18722 0.216140207168081 0.438963995165783 STAT1 1 GO:0072520 seminiferous tubule development 1/376 12/18722 0.216140207168081 0.438963995165783 ATRX 1 GO:0072711 cellular response to hydroxyurea 1/376 12/18722 0.216140207168081 0.438963995165783 ATRX 1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 1/376 12/18722 0.216140207168081 0.438963995165783 JUN 1 GO:0140289 protein mono-ADP-ribosylation 1/376 12/18722 0.216140207168081 0.438963995165783 PARP8 1 GO:1902563 regulation of neutrophil activation 1/376 12/18722 0.216140207168081 0.438963995165783 ITGB2 1 GO:1902950 regulation of dendritic spine maintenance 1/376 12/18722 0.216140207168081 0.438963995165783 FYN 1 GO:1903441 protein localization to ciliary membrane 1/376 12/18722 0.216140207168081 0.438963995165783 RAB29 1 GO:1903909 regulation of receptor clustering 1/376 12/18722 0.216140207168081 0.438963995165783 CD81 1 GO:1905205 positive regulation of connective tissue replacement 1/376 12/18722 0.216140207168081 0.438963995165783 ROCK1 1 GO:1905245 regulation of aspartic-type peptidase activity 1/376 12/18722 0.216140207168081 0.438963995165783 SORL1 1 GO:1990034 calcium ion export across plasma membrane 1/376 12/18722 0.216140207168081 0.438963995165783 CALM1 1 GO:2000105 positive regulation of DNA-dependent DNA replication 1/376 12/18722 0.216140207168081 0.438963995165783 ATRX 1 GO:2000727 positive regulation of cardiac muscle cell differentiation 1/376 12/18722 0.216140207168081 0.438963995165783 TGFB1 1 GO:2001204 regulation of osteoclast development 1/376 12/18722 0.216140207168081 0.438963995165783 TYROBP 1 GO:0009791 post-embryonic development 3/376 80/18722 0.217085181237151 0.440191039923579 PRDM1/NR4A2/ATRX 3 GO:0032204 regulation of telomere maintenance 3/376 80/18722 0.217085181237151 0.440191039923579 ATM/TERF2IP/ATRX 3 GO:0051303 establishment of chromosome localization 3/376 80/18722 0.217085181237151 0.440191039923579 ACTR3/ACTR2/CENPC 3 GO:0030282 bone mineralization 4/376 119/18722 0.217443868800672 0.44045739236937 SRGN/CCL3/TGFB1/ISG15 4 GO:0031398 positive regulation of protein ubiquitination 4/376 119/18722 0.217443868800672 0.44045739236937 PTPN22/RASSF5/LAPTM5/CBLB 4 GO:0051054 positive regulation of DNA metabolic process 6/376 201/18722 0.218239769571755 0.441838613944907 PTPRC/TGFB1/ATM/WAS/ACTR2/ATRX 6 GO:0009126 purine nucleoside monophosphate metabolic process 2/376 44/18722 0.221039948286122 0.444950545251285 GUK1/APRT 2 GO:0009262 deoxyribonucleotide metabolic process 2/376 44/18722 0.221039948286122 0.444950545251285 SAMHD1/GUK1 2 GO:0032007 negative regulation of TOR signaling 2/376 44/18722 0.221039948286122 0.444950545251285 DDIT4/ATM 2 GO:0045124 regulation of bone resorption 2/376 44/18722 0.221039948286122 0.444950545251285 TNFAIP3/CSK 2 GO:0048066 developmental pigmentation 2/376 44/18722 0.221039948286122 0.444950545251285 RAB27A/ZEB2 2 GO:0050999 regulation of nitric-oxide synthase activity 2/376 44/18722 0.221039948286122 0.444950545251285 TNF/CALM1 2 GO:0060711 labyrinthine layer development 2/376 44/18722 0.221039948286122 0.444950545251285 JUNB/CASP8 2 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 2/376 44/18722 0.221039948286122 0.444950545251285 PTPN22/CYBA 2 GO:0097178 ruffle assembly 2/376 44/18722 0.221039948286122 0.444950545251285 EVL/PFN1 2 GO:1903214 regulation of protein targeting to mitochondrion 2/376 44/18722 0.221039948286122 0.444950545251285 RAC2/TOMM7 2 GO:1903573 negative regulation of response to endoplasmic reticulum stress 2/376 44/18722 0.221039948286122 0.444950545251285 XBP1/PPP1R15A 2 GO:0009913 epidermal cell differentiation 6/376 202/18722 0.221448481766292 0.4453102578331 TXNIP/STK4/ZFP36/PRKCH/SLC9A3R1/ROCK1 6 GO:1903046 meiotic cell cycle process 6/376 202/18722 0.221448481766292 0.4453102578331 MYBL1/ATM/ACTR3/ACTR2/ATRX/CENPC 6 GO:0051897 positive regulation of protein kinase B signaling 4/376 120/18722 0.221685647635515 0.445324979050088 TNF/CCL3/TGFB1/MTDH 4 GO:0072655 establishment of protein localization to mitochondrion 4/376 120/18722 0.221685647635515 0.445324979050088 GZMB/RAC2/CALM1/TOMM7 4 GO:0008589 regulation of smoothened signaling pathway 3/376 81/18722 0.222352047392874 0.446201027264312 CD3E/RORA/PRKACB 3 GO:0046209 nitric oxide metabolic process 3/376 81/18722 0.222352047392874 0.446201027264312 KLF2/RORA/TNF 3 GO:0036294 cellular response to decreased oxygen levels 5/376 161/18722 0.22333680911471 0.447945204616719 MALAT1/RORA/CARD16/CFLAR/HP1BP3 5 GO:0034599 cellular response to oxidative stress 8/376 288/18722 0.223931894858617 0.448906411059048 ETS1/KLF2/FYN/TNFAIP3/NR4A2/JUN/FOS/MCL1 8 GO:0001838 embryonic epithelial tube formation 4/376 121/18722 0.225949188537331 0.450418373917181 STK4/TGFB1/PRKACB/PFN1 4 GO:0050000 chromosome localization 3/376 82/18722 0.227644195696397 0.450418373917181 ACTR3/ACTR2/CENPC 3 GO:1905897 regulation of response to endoplasmic reticulum stress 3/376 82/18722 0.227644195696397 0.450418373917181 PIK3R1/XBP1/PPP1R15A 3 GO:2001057 reactive nitrogen species metabolic process 3/376 82/18722 0.227644195696397 0.450418373917181 KLF2/RORA/TNF 3 GO:0006110 regulation of glycolytic process 2/376 45/18722 0.228464858538532 0.450418373917181 DDIT4/STAT3 2 GO:0031670 cellular response to nutrient 2/376 45/18722 0.228464858538532 0.450418373917181 XBP1/PIM1 2 GO:0046189 phenol-containing compound biosynthetic process 2/376 45/18722 0.228464858538532 0.450418373917181 NR4A2/ZEB2 2 GO:0051985 negative regulation of chromosome segregation 2/376 45/18722 0.228464858538532 0.450418373917181 ATM/DUSP1 2 GO:1904646 cellular response to amyloid-beta 2/376 45/18722 0.228464858538532 0.450418373917181 FYN/ITGA4 2 GO:1905819 negative regulation of chromosome separation 2/376 45/18722 0.228464858538532 0.450418373917181 ATM/DUSP1 2 GO:0061025 membrane fusion 5/376 163/18722 0.230661805624915 0.450418373917181 CORO1A/PIP4K2A/SAMD9/RAB8B/VAMP2 5 GO:0002087 regulation of respiratory gaseous exchange by nervous system process 1/376 13/18722 0.231892814442523 0.450418373917181 GLS 1 GO:0002551 mast cell chemotaxis 1/376 13/18722 0.231892814442523 0.450418373917181 RAC2 1 GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 1/376 13/18722 0.231892814442523 0.450418373917181 STAT1 1 GO:0005513 detection of calcium ion 1/376 13/18722 0.231892814442523 0.450418373917181 CALM1 1 GO:0007183 SMAD protein complex assembly 1/376 13/18722 0.231892814442523 0.450418373917181 TGFB1 1 GO:0008298 intracellular mRNA localization 1/376 13/18722 0.231892814442523 0.450418373917181 ZFP36 1 GO:0009143 nucleoside triphosphate catabolic process 1/376 13/18722 0.231892814442523 0.450418373917181 SAMHD1 1 GO:0010745 negative regulation of macrophage derived foam cell differentiation 1/376 13/18722 0.231892814442523 0.450418373917181 NFKBIA 1 GO:0021694 cerebellar Purkinje cell layer formation 1/376 13/18722 0.231892814442523 0.450418373917181 RORA 1 GO:0030836 positive regulation of actin filament depolymerization 1/376 13/18722 0.231892814442523 0.450418373917181 PLEK 1 GO:0031053 primary miRNA processing 1/376 13/18722 0.231892814442523 0.450418373917181 STAT3 1 GO:0032252 secretory granule localization 1/376 13/18722 0.231892814442523 0.450418373917181 RASGRP1 1 GO:0032905 transforming growth factor beta1 production 1/376 13/18722 0.231892814442523 0.450418373917181 TYROBP 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/376 13/18722 0.231892814442523 0.450418373917181 ATRX 1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway 1/376 13/18722 0.231892814442523 0.450418373917181 TNFAIP3 1 GO:0036462 TRAIL-activated apoptotic signaling pathway 1/376 13/18722 0.231892814442523 0.450418373917181 CASP8 1 GO:0042362 fat-soluble vitamin biosynthetic process 1/376 13/18722 0.231892814442523 0.450418373917181 TNF 1 GO:0043247 telomere maintenance in response to DNA damage 1/376 13/18722 0.231892814442523 0.450418373917181 TERF2IP 1 GO:0043970 histone H3-K9 acetylation 1/376 13/18722 0.231892814442523 0.450418373917181 KMT2A 1 GO:0044090 positive regulation of vacuole organization 1/376 13/18722 0.231892814442523 0.450418373917181 PIP4K2A 1 GO:0044794 positive regulation by host of viral process 1/376 13/18722 0.231892814442523 0.450418373917181 CFL1 1 GO:0048070 regulation of developmental pigmentation 1/376 13/18722 0.231892814442523 0.450418373917181 ZEB2 1 GO:0048302 regulation of isotype switching to IgG isotypes 1/376 13/18722 0.231892814442523 0.450418373917181 PTPRC 1 GO:0048711 positive regulation of astrocyte differentiation 1/376 13/18722 0.231892814442523 0.450418373917181 ID2 1 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1/376 13/18722 0.231892814442523 0.450418373917181 CALM1 1 GO:0051451 myoblast migration 1/376 13/18722 0.231892814442523 0.450418373917181 ROCK1 1 GO:0051709 regulation of killing of cells of other organism 1/376 13/18722 0.231892814442523 0.450418373917181 PRF1 1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1/376 13/18722 0.231892814442523 0.450418373917181 CDC42 1 GO:0055062 phosphate ion homeostasis 1/376 13/18722 0.231892814442523 0.450418373917181 SLC9A3R1 1 GO:0060707 trophoblast giant cell differentiation 1/376 13/18722 0.231892814442523 0.450418373917181 PRDM1 1 GO:0070234 positive regulation of T cell apoptotic process 1/376 13/18722 0.231892814442523 0.450418373917181 CCL5 1 GO:0070254 mucus secretion 1/376 13/18722 0.231892814442523 0.450418373917181 CYBA 1 GO:0072506 trivalent inorganic anion homeostasis 1/376 13/18722 0.231892814442523 0.450418373917181 SLC9A3R1 1 GO:0072672 neutrophil extravasation 1/376 13/18722 0.231892814442523 0.450418373917181 CD99 1 GO:0072710 response to hydroxyurea 1/376 13/18722 0.231892814442523 0.450418373917181 ATRX 1 GO:0090042 tubulin deacetylation 1/376 13/18722 0.231892814442523 0.450418373917181 FLNA 1 GO:0090161 Golgi ribbon formation 1/376 13/18722 0.231892814442523 0.450418373917181 GCC2 1 GO:0120305 regulation of pigmentation 1/376 13/18722 0.231892814442523 0.450418373917181 ZEB2 1 GO:1900044 regulation of protein K63-linked ubiquitination 1/376 13/18722 0.231892814442523 0.450418373917181 PTPN22 1 GO:1900121 negative regulation of receptor binding 1/376 13/18722 0.231892814442523 0.450418373917181 B2M 1 GO:1900272 negative regulation of long-term synaptic potentiation 1/376 13/18722 0.231892814442523 0.450418373917181 TYROBP 1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/376 13/18722 0.231892814442523 0.450418373917181 STK4 1 GO:1902947 regulation of tau-protein kinase activity 1/376 13/18722 0.231892814442523 0.450418373917181 SORL1 1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 1/376 13/18722 0.231892814442523 0.450418373917181 TMSB4X 1 GO:1903054 negative regulation of extracellular matrix organization 1/376 13/18722 0.231892814442523 0.450418373917181 TGFB1 1 GO:1903977 positive regulation of glial cell migration 1/376 13/18722 0.231892814442523 0.450418373917181 CCL3 1 GO:1904478 regulation of intestinal absorption 1/376 13/18722 0.231892814442523 0.450418373917181 EPB41 1 GO:1905203 regulation of connective tissue replacement 1/376 13/18722 0.231892814442523 0.450418373917181 ROCK1 1 GO:1905244 regulation of modification of synaptic structure 1/376 13/18722 0.231892814442523 0.450418373917181 CDC42 1 GO:1990403 embryonic brain development 1/376 13/18722 0.231892814442523 0.450418373917181 RPL10 1 GO:2001198 regulation of dendritic cell differentiation 1/376 13/18722 0.231892814442523 0.450418373917181 HLA-B 1 GO:0048678 response to axon injury 3/376 83/18722 0.232960100465012 0.452264724099158 TYROBP/FLNA/LGALS1 3 GO:0050680 negative regulation of epithelial cell proliferation 5/376 164/18722 0.234350234505111 0.454676519712326 B2M/RUNX3/TNF/TGFB1/STAT1 5 GO:0048863 stem cell differentiation 6/376 206/18722 0.234437080357478 0.454676519712326 PTPRC/ZFP36L2/LBH/SEMA4D/N4BP2L2/STAT3 6 GO:1901988 negative regulation of cell cycle phase transition 7/376 249/18722 0.235421561508211 0.456156446693683 ZFP36L2/ATM/CDKN2D/RBL2/DUSP1/TAOK3/PRMT2 7 GO:0001974 blood vessel remodeling 2/376 46/18722 0.235906456561069 0.456156446693683 TGFB1/FLNA 2 GO:0033047 regulation of mitotic sister chromatid segregation 2/376 46/18722 0.235906456561069 0.456156446693683 ATM/DUSP1 2 GO:0035094 response to nicotine 2/376 46/18722 0.235906456561069 0.456156446693683 B2M/TNF 2 GO:0044818 mitotic G2/M transition checkpoint 2/376 46/18722 0.235906456561069 0.456156446693683 ATM/TAOK3 2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 2/376 46/18722 0.235906456561069 0.456156446693683 CCND2/KMT2E 2 GO:0006970 response to osmotic stress 3/376 84/18722 0.238298254613979 0.460092544409153 TSC22D3/TNF/RCSD1 3 GO:1900542 regulation of purine nucleotide metabolic process 3/376 84/18722 0.238298254613979 0.460092544409153 TMSB4X/DDIT4/STAT3 3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 3/376 84/18722 0.238298254613979 0.460092544409153 ATM/RBL2/PRMT2 3 GO:0010508 positive regulation of autophagy 4/376 124/18722 0.238862385477043 0.460952063607342 PIP4K2A/TRIM22/MTDH/ROCK1 4 GO:0010948 negative regulation of cell cycle process 8/376 294/18722 0.240253306745091 0.463145140386574 ZFP36L2/ATM/CDKN2D/RBL2/DUSP1/TAOK3/PRMT2/ATRX 8 GO:0051604 protein maturation 8/376 294/18722 0.240253306745091 0.463145140386574 CST7/SRGN/IFI16/PRKACB/CASP8/CARD16/SORL1/PYCARD 8 GO:0048568 embryonic organ development 11/376 427/18722 0.241519996650169 0.463145140386574 EOMES/PRDM1/TNF/STK4/TGFB1/RPL10/JUNB/CASP8/ID2/KMT2A/SLC9A3R1 11 GO:0007568 aging 9/376 339/18722 0.24331373791333 0.463145140386574 B2M/ATM/JUN/FOS/ID2/LITAF/JUND/UCP2/STAT3 9 GO:0001754 eye photoreceptor cell differentiation 2/376 47/18722 0.243361088581236 0.463145140386574 PRDM1/STAT3 2 GO:0007595 lactation 2/376 47/18722 0.243361088581236 0.463145140386574 XBP1/APRT 2 GO:0010712 regulation of collagen metabolic process 2/376 47/18722 0.243361088581236 0.463145140386574 VIM/TGFB1 2 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 2/376 47/18722 0.243361088581236 0.463145140386574 KLF2/JUN 2 GO:0045581 negative regulation of T cell differentiation 2/376 47/18722 0.243361088581236 0.463145140386574 RUNX3/IRF1 2 GO:0050798 activated T cell proliferation 2/376 47/18722 0.243361088581236 0.463145140386574 FYN/PYCARD 2 GO:0051489 regulation of filopodium assembly 2/376 47/18722 0.243361088581236 0.463145140386574 PIK3R1/CDC42 2 GO:0061001 regulation of dendritic spine morphogenesis 2/376 47/18722 0.243361088581236 0.463145140386574 CFL1/ACTR2 2 GO:0090279 regulation of calcium ion import 2/376 47/18722 0.243361088581236 0.463145140386574 FYN/CCL3 2 GO:0101023 vascular endothelial cell proliferation 2/376 47/18722 0.243361088581236 0.463145140386574 ITGA4/STAT3 2 GO:1905562 regulation of vascular endothelial cell proliferation 2/376 47/18722 0.243361088581236 0.463145140386574 ITGA4/STAT3 2 GO:0009142 nucleoside triphosphate biosynthetic process 3/376 85/18722 0.243657170168482 0.463145140386574 TMSB4X/TGFB1/STAT3 3 GO:0032092 positive regulation of protein binding 3/376 85/18722 0.243657170168482 0.463145140386574 B2M/STK4/EPB41 3 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 3/376 85/18722 0.243657170168482 0.463145140386574 CCL5/FYN/TNF 3 GO:0072384 organelle transport along microtubule 3/376 85/18722 0.243657170168482 0.463145140386574 RASGRP1/SUN2/CDC42 3 GO:2000779 regulation of double-strand break repair 3/376 85/18722 0.243657170168482 0.463145140386574 WAS/TERF2IP/ACTR2 3 GO:0061448 connective tissue development 7/376 252/18722 0.244394323517857 0.463145140386574 CRIP1/RUNX3/TGFB1/CD44/XBP1/SORL1/CFLAR 7 GO:0034767 positive regulation of ion transmembrane transport 5/376 167/18722 0.245513332420534 0.463145140386574 TMSB4X/XCL1/CALM1/FLNA/SLC9A3R1 5 GO:0050890 cognition 8/376 296/18722 0.245782262026523 0.463145140386574 B2M/FYN/CCND2/TNF/JUN/FOS/BTG2/ACTR2 8 GO:0000212 meiotic spindle organization 1/376 14/18722 0.247329679147724 0.463145140386574 ATRX 1 GO:0001711 endodermal cell fate commitment 1/376 14/18722 0.247329679147724 0.463145140386574 EOMES 1 GO:0001921 positive regulation of receptor recycling 1/376 14/18722 0.247329679147724 0.463145140386574 RAB29 1 GO:0002467 germinal center formation 1/376 14/18722 0.247329679147724 0.463145140386574 TNFAIP3 1 GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1/376 14/18722 0.247329679147724 0.463145140386574 HLA-E 1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 1/376 14/18722 0.247329679147724 0.463145140386574 CBLB 1 GO:0010896 regulation of triglyceride catabolic process 1/376 14/18722 0.247329679147724 0.463145140386574 SORL1 1 GO:0010989 negative regulation of low-density lipoprotein particle clearance 1/376 14/18722 0.247329679147724 0.463145140386574 CSK 1 GO:0015812 gamma-aminobutyric acid transport 1/376 14/18722 0.247329679147724 0.463145140386574 SLC9A3R1 1 GO:0030213 hyaluronan biosynthetic process 1/376 14/18722 0.247329679147724 0.463145140386574 TGFB1 1 GO:0031650 regulation of heat generation 1/376 14/18722 0.247329679147724 0.463145140386574 TNF 1 GO:0038166 angiotensin-activated signaling pathway 1/376 14/18722 0.247329679147724 0.463145140386574 ROCK1 1 GO:0043173 nucleotide salvage 1/376 14/18722 0.247329679147724 0.463145140386574 APRT 1 GO:0043249 erythrocyte maturation 1/376 14/18722 0.247329679147724 0.463145140386574 KLF2 1 GO:0043455 regulation of secondary metabolic process 1/376 14/18722 0.247329679147724 0.463145140386574 ZEB2 1 GO:0043558 regulation of translational initiation in response to stress 1/376 14/18722 0.247329679147724 0.463145140386574 PPP1R15A 1 GO:0043650 dicarboxylic acid biosynthetic process 1/376 14/18722 0.247329679147724 0.463145140386574 GLS 1 GO:0044154 histone H3-K14 acetylation 1/376 14/18722 0.247329679147724 0.463145140386574 KMT2A 1 GO:0045579 positive regulation of B cell differentiation 1/376 14/18722 0.247329679147724 0.463145140386574 XBP1 1 GO:0046325 negative regulation of glucose import 1/376 14/18722 0.247329679147724 0.463145140386574 TNF 1 GO:0048021 regulation of melanin biosynthetic process 1/376 14/18722 0.247329679147724 0.463145140386574 ZEB2 1 GO:0048291 isotype switching to IgG isotypes 1/376 14/18722 0.247329679147724 0.463145140386574 PTPRC 1 GO:0051589 negative regulation of neurotransmitter transport 1/376 14/18722 0.247329679147724 0.463145140386574 RAP1B 1 GO:0060088 auditory receptor cell stereocilium organization 1/376 14/18722 0.247329679147724 0.463145140386574 SLC9A3R1 1 GO:0060576 intestinal epithelial cell development 1/376 14/18722 0.247329679147724 0.463145140386574 PRDM1 1 GO:0070307 lens fiber cell development 1/376 14/18722 0.247329679147724 0.463145140386574 VIM 1 GO:0072160 nephron tubule epithelial cell differentiation 1/376 14/18722 0.247329679147724 0.463145140386574 STAT1 1 GO:0072540 T-helper 17 cell lineage commitment 1/376 14/18722 0.247329679147724 0.463145140386574 STAT3 1 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 1/376 14/18722 0.247329679147724 0.463145140386574 AKAP13 1 GO:0090128 regulation of synapse maturation 1/376 14/18722 0.247329679147724 0.463145140386574 YWHAZ 1 GO:0097531 mast cell migration 1/376 14/18722 0.247329679147724 0.463145140386574 RAC2 1 GO:0098734 macromolecule depalmitoylation 1/376 14/18722 0.247329679147724 0.463145140386574 ABHD17A 1 GO:1900376 regulation of secondary metabolite biosynthetic process 1/376 14/18722 0.247329679147724 0.463145140386574 ZEB2 1 GO:1901722 regulation of cell proliferation involved in kidney development 1/376 14/18722 0.247329679147724 0.463145140386574 CFLAR 1 GO:1902036 regulation of hematopoietic stem cell differentiation 1/376 14/18722 0.247329679147724 0.463145140386574 N4BP2L2 1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/376 14/18722 0.247329679147724 0.463145140386574 CD44 1 GO:1902916 positive regulation of protein polyubiquitination 1/376 14/18722 0.247329679147724 0.463145140386574 PTPN22 1 GO:1905049 negative regulation of metallopeptidase activity 1/376 14/18722 0.247329679147724 0.463145140386574 SORL1 1 GO:0009743 response to carbohydrate 7/376 253/18722 0.247409145961344 0.463145140386574 TXNIP/CYBA/LGALS1/UCP2/VAMP2/XBP1/RAP1B 7 GO:0006140 regulation of nucleotide metabolic process 3/376 86/18722 0.249035378734957 0.465739426929517 TMSB4X/DDIT4/STAT3 3 GO:0045921 positive regulation of exocytosis 3/376 86/18722 0.249035378734957 0.465739426929517 HLA-F/ITGB2/RAB27A 3 GO:0002686 negative regulation of leukocyte migration 2/376 48/18722 0.25082524010705 0.46750736191189 PTGER4/DUSP1 2 GO:0042149 cellular response to glucose starvation 2/376 48/18722 0.25082524010705 0.46750736191189 IFI16/XBP1 2 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 2/376 48/18722 0.25082524010705 0.46750736191189 SAMHD1/ATRX 2 GO:0045839 negative regulation of mitotic nuclear division 2/376 48/18722 0.25082524010705 0.46750736191189 ATM/DUSP1 2 GO:0061647 histone H3-K9 modification 2/376 48/18722 0.25082524010705 0.46750736191189 KMT2A/ATRX 2 GO:0097720 calcineurin-mediated signaling 2/376 48/18722 0.25082524010705 0.46750736191189 TBC1D10C/TNF 2 GO:1905710 positive regulation of membrane permeability 2/376 48/18722 0.25082524010705 0.46750736191189 GZMB/LAPTM5 2 GO:0043491 protein kinase B signaling 6/376 211/18722 0.250993645176821 0.46759633416355 CCL5/TNF/CCL3/TGFB1/MTDH/SLC9A3R1 6 GO:0009152 purine ribonucleotide biosynthetic process 5/376 169/18722 0.253031976729948 0.470407638556615 TMSB4X/TGFB1/STAT3/GUK1/APRT 5 GO:0031214 biomineral tissue development 5/376 169/18722 0.253031976729948 0.470407638556615 SRGN/CCL3/TGFB1/ISG15/ROCK1 5 GO:0007611 learning or memory 7/376 255/18722 0.253473151986393 0.470407638556615 B2M/FYN/CCND2/JUN/FOS/BTG2/ACTR2 7 GO:1903362 regulation of cellular protein catabolic process 7/376 255/18722 0.253473151986393 0.470407638556615 PYHIN1/MSN/TNFAIP3/PSME1/LAPTM5/RNF19A/CD81 7 GO:0042254 ribosome biogenesis 8/376 299/18722 0.254153445503714 0.470407638556615 ISG20/RPL10/RPS27/GTF3A/RPL35A/RPL3/LYAR/DDX17 8 GO:0009749 response to glucose 6/376 212/18722 0.254344355519958 0.470407638556615 TXNIP/CYBA/LGALS1/UCP2/VAMP2/XBP1 6 GO:0048041 focal adhesion assembly 3/376 87/18722 0.25443143193349 0.470407638556615 MACF1/ACTG1/ROCK1 3 GO:1903578 regulation of ATP metabolic process 3/376 87/18722 0.25443143193349 0.470407638556615 TMSB4X/DDIT4/STAT3 3 GO:2000177 regulation of neural precursor cell proliferation 3/376 87/18722 0.25443143193349 0.470407638556615 FLNA/ID2/BTG2 3 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 2/376 49/18722 0.258295531831664 0.470407638556615 PTPRC/TGFB1 2 GO:0002208 somatic diversification of immunoglobulins involved in immune response 2/376 49/18722 0.258295531831664 0.470407638556615 PTPRC/TGFB1 2 GO:0002762 negative regulation of myeloid leukocyte differentiation 2/376 49/18722 0.258295531831664 0.470407638556615 CCL3/PIK3R1 2 GO:0006953 acute-phase response 2/376 49/18722 0.258295531831664 0.470407638556615 TNF/STAT3 2 GO:0014075 response to amine 2/376 49/18722 0.258295531831664 0.470407638556615 CALM1/NR4A2 2 GO:0032692 negative regulation of interleukin-1 production 2/376 49/18722 0.258295531831664 0.470407638556615 TNFAIP3/CARD16 2 GO:0045190 isotype switching 2/376 49/18722 0.258295531831664 0.470407638556615 PTPRC/TGFB1 2 GO:0045778 positive regulation of ossification 2/376 49/18722 0.258295531831664 0.470407638556615 TGFB1/ISG15 2 GO:0050832 defense response to fungus 2/376 49/18722 0.258295531831664 0.470407638556615 GNLY/SPON2 2 GO:0051445 regulation of meiotic cell cycle 2/376 49/18722 0.258295531831664 0.470407638556615 PRKACB/DUSP1 2 GO:0070169 positive regulation of biomineral tissue development 2/376 49/18722 0.258295531831664 0.470407638556615 TGFB1/ISG15 2 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 2/376 49/18722 0.258295531831664 0.470407638556615 TNF/JUN 2 GO:0001843 neural tube closure 3/376 88/18722 0.259843901792869 0.470407638556615 TGFB1/PRKACB/PFN1 3 GO:0007260 tyrosine phosphorylation of STAT protein 3/376 88/18722 0.259843901792869 0.470407638556615 CCL5/FYN/TNF 3 GO:1901657 glycosyl compound metabolic process 3/376 88/18722 0.259843901792869 0.470407638556615 APOBEC3G/APOBEC3C/APRT 3 GO:0110148 biomineralization 5/376 171/18722 0.260607285397392 0.470407638556615 SRGN/CCL3/TGFB1/ISG15/ROCK1 5 GO:0006022 aminoglycan metabolic process 4/376 129/18722 0.260745393026568 0.470407638556615 TGFB1/CD44/PIM1/CHST12 4 GO:0002730 regulation of dendritic cell cytokine production 1/376 15/18722 0.262457113434684 0.470407638556615 BST2 1 GO:0009163 nucleoside biosynthetic process 1/376 15/18722 0.262457113434684 0.470407638556615 APRT 1 GO:0009263 deoxyribonucleotide biosynthetic process 1/376 15/18722 0.262457113434684 0.470407638556615 GUK1 1 GO:0010763 positive regulation of fibroblast migration 1/376 15/18722 0.262457113434684 0.470407638556615 TGFB1 1 GO:0010832 negative regulation of myotube differentiation 1/376 15/18722 0.262457113434684 0.470407638556615 XBP1 1 GO:0016446 somatic hypermutation of immunoglobulin genes 1/376 15/18722 0.262457113434684 0.470407638556615 SAMHD1 1 GO:0018216 peptidyl-arginine methylation 1/376 15/18722 0.262457113434684 0.470407638556615 PRMT2 1 GO:0021542 dentate gyrus development 1/376 15/18722 0.262457113434684 0.470407638556615 BTG2 1 GO:0023035 CD40 signaling pathway 1/376 15/18722 0.262457113434684 0.470407638556615 TNFAIP3 1 GO:0030852 regulation of granulocyte differentiation 1/376 15/18722 0.262457113434684 0.470407638556615 EVI2B 1 GO:0032486 Rap protein signal transduction 1/376 15/18722 0.262457113434684 0.470407638556615 RAP1B 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/376 15/18722 0.262457113434684 0.470407638556615 RASGRP1 1 GO:0032897 negative regulation of viral transcription 1/376 15/18722 0.262457113434684 0.470407638556615 ZFP36 1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 1/376 15/18722 0.262457113434684 0.470407638556615 LBH 1 GO:0034380 high-density lipoprotein particle assembly 1/376 15/18722 0.262457113434684 0.470407638556615 PRKACB 1 GO:0034404 nucleobase-containing small molecule biosynthetic process 1/376 15/18722 0.262457113434684 0.470407638556615 APRT 1 GO:0035493 SNARE complex assembly 1/376 15/18722 0.262457113434684 0.470407638556615 VAMP2 1 GO:0036124 histone H3-K9 trimethylation 1/376 15/18722 0.262457113434684 0.470407638556615 ATRX 1 GO:0042159 lipoprotein catabolic process 1/376 15/18722 0.262457113434684 0.470407638556615 ABHD17A 1 GO:0042976 activation of Janus kinase activity 1/376 15/18722 0.262457113434684 0.470407638556615 CCL5 1 GO:0043508 negative regulation of JUN kinase activity 1/376 15/18722 0.262457113434684 0.470407638556615 PTPN22 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/376 15/18722 0.262457113434684 0.470407638556615 CD44 1 GO:0044406 adhesion of symbiont to host 1/376 15/18722 0.262457113434684 0.470407638556615 CD81 1 GO:0045176 apical protein localization 1/376 15/18722 0.262457113434684 0.470407638556615 ACTB 1 GO:0045346 regulation of MHC class II biosynthetic process 1/376 15/18722 0.262457113434684 0.470407638556615 XBP1 1 GO:0045475 locomotor rhythm 1/376 15/18722 0.262457113434684 0.470407638556615 ID2 1 GO:0046834 lipid phosphorylation 1/376 15/18722 0.262457113434684 0.470407638556615 DGKZ 1 GO:0048308 organelle inheritance 1/376 15/18722 0.262457113434684 0.470407638556615 YWHAZ 1 GO:0048313 Golgi inheritance 1/376 15/18722 0.262457113434684 0.470407638556615 YWHAZ 1 GO:0051127 positive regulation of actin nucleation 1/376 15/18722 0.262457113434684 0.470407638556615 WAS 1 GO:0051284 positive regulation of sequestering of calcium ion 1/376 15/18722 0.262457113434684 0.470407638556615 CALM1 1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore 1/376 15/18722 0.262457113434684 0.470407638556615 CENPC 1 GO:0051775 response to redox state 1/376 15/18722 0.262457113434684 0.470407638556615 ARHGDIB 1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1/376 15/18722 0.262457113434684 0.470407638556615 SORL1 1 GO:0070207 protein homotrimerization 1/376 15/18722 0.262457113434684 0.470407638556615 ALOX5AP 1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 1/376 15/18722 0.262457113434684 0.470407638556615 TBC1D10C 1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 1/376 15/18722 0.262457113434684 0.470407638556615 TNF 1 GO:0071474 cellular hyperosmotic response 1/376 15/18722 0.262457113434684 0.470407638556615 RCSD1 1 GO:0072075 metanephric mesenchyme development 1/376 15/18722 0.262457113434684 0.470407638556615 STAT1 1 GO:0090594 inflammatory response to wounding 1/376 15/18722 0.262457113434684 0.470407638556615 TGFB1 1 GO:0099170 postsynaptic modulation of chemical synaptic transmission 1/376 15/18722 0.262457113434684 0.470407638556615 RNF19A 1 GO:0106057 negative regulation of calcineurin-mediated signaling 1/376 15/18722 0.262457113434684 0.470407638556615 TBC1D10C 1 GO:0106058 positive regulation of calcineurin-mediated signaling 1/376 15/18722 0.262457113434684 0.470407638556615 TNF 1 GO:0110156 methylguanosine-cap decapping 1/376 15/18722 0.262457113434684 0.470407638556615 ZFP36 1 GO:0150011 regulation of neuron projection arborization 1/376 15/18722 0.262457113434684 0.470407638556615 MACF1 1 GO:1900029 positive regulation of ruffle assembly 1/376 15/18722 0.262457113434684 0.470407638556615 PFN1 1 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 1/376 15/18722 0.262457113434684 0.470407638556615 PPP1R15A 1 GO:1901660 calcium ion export 1/376 15/18722 0.262457113434684 0.470407638556615 CALM1 1 GO:1901741 positive regulation of myoblast fusion 1/376 15/18722 0.262457113434684 0.470407638556615 CD53 1 GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I 1/376 15/18722 0.262457113434684 0.470407638556615 NCL 1 GO:1901841 regulation of high voltage-gated calcium channel activity 1/376 15/18722 0.262457113434684 0.470407638556615 CALM1 1 GO:1902018 negative regulation of cilium assembly 1/376 15/18722 0.262457113434684 0.470407638556615 ODF2L 1 GO:1905288 vascular associated smooth muscle cell apoptotic process 1/376 15/18722 0.262457113434684 0.470407638556615 STK4 1 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 1/376 15/18722 0.262457113434684 0.470407638556615 STK4 1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity 1/376 15/18722 0.262457113434684 0.470407638556615 SLC9A3R1 1 GO:2001028 positive regulation of endothelial cell chemotaxis 1/376 15/18722 0.262457113434684 0.470407638556615 TMSB4X 1 GO:0045165 cell fate commitment 7/376 258/18722 0.262651306507023 0.470538054884288 EOMES/PRDM1/SPN/ID2/STAT3/CDC42/MCL1 7 GO:0001678 cellular glucose homeostasis 5/376 172/18722 0.264414959369369 0.473260031203836 CYBA/LGALS1/UCP2/PIK3R1/XBP1 5 GO:1901136 carbohydrate derivative catabolic process 5/376 172/18722 0.264414959369369 0.473260031203836 APOBEC3G/APOBEC3C/TGFB1/CD44/SAMHD1 5 GO:0051781 positive regulation of cell division 3/376 89/18722 0.265271381109863 0.474149987627393 TGFB1/LBH/CDC42 3 GO:0060606 tube closure 3/376 89/18722 0.265271381109863 0.474149987627393 TGFB1/PRKACB/PFN1 3 GO:0050873 brown fat cell differentiation 2/376 50/18722 0.2657687156456 0.474149987627393 PLAC8/PIM1 2 GO:0060425 lung morphogenesis 2/376 50/18722 0.2657687156456 0.474149987627393 TNF/CDC42 2 GO:0110151 positive regulation of biomineralization 2/376 50/18722 0.2657687156456 0.474149987627393 TGFB1/ISG15 2 GO:1904036 negative regulation of epithelial cell apoptotic process 2/376 50/18722 0.2657687156456 0.474149987627393 TNFAIP3/CFLAR 2 GO:2000677 regulation of transcription regulatory region DNA binding 2/376 50/18722 0.2657687156456 0.474149987627393 TMSB4X/TGFB1 2 GO:0000723 telomere maintenance 4/376 131/18722 0.269606682168285 0.478603586385154 ATM/SP100/TERF2IP/ATRX 4 GO:0018022 peptidyl-lysine methylation 4/376 131/18722 0.269606682168285 0.478603586385154 KMT2A/KMT2E/MLLT6/ATRX 4 GO:0019827 stem cell population maintenance 4/376 131/18722 0.269606682168285 0.478603586385154 ZFP36L2/LBH/STAT3/DDX6 4 GO:0002028 regulation of sodium ion transport 3/376 90/18722 0.270712483774225 0.478603586385154 FXYD5/SLC9A3R1/MLLT6 3 GO:0034644 cellular response to UV 3/376 90/18722 0.270712483774225 0.478603586385154 CRIP1/PIK3R1/CARD16 3 GO:0061097 regulation of protein tyrosine kinase activity 3/376 90/18722 0.270712483774225 0.478603586385154 CCL5/PTPRC/CBLB 3 GO:0006310 DNA recombination 8/376 305/18722 0.271156611515855 0.478603586385154 IL7R/PTPRC/TGFB1/ATM/WAS/TERF2IP/SAMHD1/ACTR2 8 GO:0007584 response to nutrient 5/376 174/18722 0.272067894677084 0.478603586385154 CD3E/CDKN2D/STAT1/XBP1/PIM1 5 GO:0048639 positive regulation of developmental growth 5/376 174/18722 0.272067894677084 0.478603586385154 HOPX/CXCR4/SEMA4D/PIM1/MACF1 5 GO:0014009 glial cell proliferation 2/376 51/18722 0.273241670753947 0.478603586385154 TNF/PRKCH 2 GO:0032964 collagen biosynthetic process 2/376 51/18722 0.273241670753947 0.478603586385154 VIM/TGFB1 2 GO:0045104 intermediate filament cytoskeleton organization 2/376 51/18722 0.273241670753947 0.478603586385154 VIM/MACF1 2 GO:0045668 negative regulation of osteoblast differentiation 2/376 51/18722 0.273241670753947 0.478603586385154 TNF/SEMA4D 2 GO:0046850 regulation of bone remodeling 2/376 51/18722 0.273241670753947 0.478603586385154 TNFAIP3/CSK 2 GO:0050982 detection of mechanical stimulus 2/376 51/18722 0.273241670753947 0.478603586385154 FYN/CXCR4 2 GO:0035264 multicellular organism growth 4/376 132/18722 0.274057403835236 0.478603586385154 KLF2/PLAC8/STAT3/ATRX 4 GO:0072175 epithelial tube formation 4/376 132/18722 0.274057403835236 0.478603586385154 STK4/TGFB1/PRKACB/PFN1 4 GO:0009636 response to toxic substance 7/376 262/18722 0.275031592939721 0.478603586385154 CCL4/CCL5/MBP/ALOX5AP/CCL3/FOS/PIM1 7 GO:0050954 sensory perception of mechanical stimulus 5/376 175/18722 0.27591217845909 0.478603586385154 MBP/FYN/CXCR4/CDKN2D/SLC9A3R1 5 GO:0042147 retrograde transport, endosome to Golgi 3/376 91/18722 0.276165845060875 0.478603586385154 TBC1D10C/RAB29/GCC2 3 GO:0001845 phagolysosome assembly 1/376 16/18722 0.277281303596044 0.478603586385154 CORO1A 1 GO:0001977 renal system process involved in regulation of blood volume 1/376 16/18722 0.277281303596044 0.478603586385154 CYBA 1 GO:0002093 auditory receptor cell morphogenesis 1/376 16/18722 0.277281303596044 0.478603586385154 SLC9A3R1 1 GO:0002371 dendritic cell cytokine production 1/376 16/18722 0.277281303596044 0.478603586385154 BST2 1 GO:0002399 MHC class II protein complex assembly 1/376 16/18722 0.277281303596044 0.478603586385154 B2M 1 GO:0002503 peptide antigen assembly with MHC class II protein complex 1/376 16/18722 0.277281303596044 0.478603586385154 B2M 1 GO:0002566 somatic diversification of immune receptors via somatic mutation 1/376 16/18722 0.277281303596044 0.478603586385154 SAMHD1 1 GO:0002693 positive regulation of cellular extravasation 1/376 16/18722 0.277281303596044 0.478603586385154 CD99 1 GO:0002713 negative regulation of B cell mediated immunity 1/376 16/18722 0.277281303596044 0.478603586385154 PTPN6 1 GO:0002827 positive regulation of T-helper 1 type immune response 1/376 16/18722 0.277281303596044 0.478603586385154 XCL1 1 GO:0002890 negative regulation of immunoglobulin mediated immune response 1/376 16/18722 0.277281303596044 0.478603586385154 PTPN6 1 GO:0002921 negative regulation of humoral immune response 1/376 16/18722 0.277281303596044 0.478603586385154 PTPN6 1 GO:0003084 positive regulation of systemic arterial blood pressure 1/376 16/18722 0.277281303596044 0.478603586385154 CYBA 1 GO:0006857 oligopeptide transport 1/376 16/18722 0.277281303596044 0.478603586385154 SLC9A3R1 1 GO:0009048 dosage compensation by inactivation of X chromosome 1/376 16/18722 0.277281303596044 0.478603586385154 XIST 1 GO:0010225 response to UV-C 1/376 16/18722 0.277281303596044 0.478603586385154 CARD16 1 GO:0010649 regulation of cell communication by electrical coupling 1/376 16/18722 0.277281303596044 0.478603586385154 CALM1 1 GO:0010919 regulation of inositol phosphate biosynthetic process 1/376 16/18722 0.277281303596044 0.478603586385154 PLEK 1 GO:0021535 cell migration in hindbrain 1/376 16/18722 0.277281303596044 0.478603586385154 FLNA 1 GO:0034393 positive regulation of smooth muscle cell apoptotic process 1/376 16/18722 0.277281303596044 0.478603586385154 STK4 1 GO:0035970 peptidyl-threonine dephosphorylation 1/376 16/18722 0.277281303596044 0.478603586385154 DUSP1 1 GO:0043923 positive regulation by host of viral transcription 1/376 16/18722 0.277281303596044 0.478603586385154 JUN 1 GO:0044065 regulation of respiratory system process 1/376 16/18722 0.277281303596044 0.478603586385154 GLS 1 GO:0044849 estrous cycle 1/376 16/18722 0.277281303596044 0.478603586385154 ETS1 1 GO:0045342 MHC class II biosynthetic process 1/376 16/18722 0.277281303596044 0.478603586385154 XBP1 1 GO:0046037 GMP metabolic process 1/376 16/18722 0.277281303596044 0.478603586385154 GUK1 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/376 16/18722 0.277281303596044 0.478603586385154 KLF2 1 GO:0048557 embryonic digestive tract morphogenesis 1/376 16/18722 0.277281303596044 0.478603586385154 ID2 1 GO:0050965 detection of temperature stimulus involved in sensory perception of pain 1/376 16/18722 0.277281303596044 0.478603586385154 CXCR4 1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1/376 16/18722 0.277281303596044 0.478603586385154 TNF 1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 1/376 16/18722 0.277281303596044 0.478603586385154 STAT1 1 GO:0055089 fatty acid homeostasis 1/376 16/18722 0.277281303596044 0.478603586385154 XBP1 1 GO:0060330 regulation of response to interferon-gamma 1/376 16/18722 0.277281303596044 0.478603586385154 TXK 1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway 1/376 16/18722 0.277281303596044 0.478603586385154 TXK 1 GO:0070230 positive regulation of lymphocyte apoptotic process 1/376 16/18722 0.277281303596044 0.478603586385154 CCL5 1 GO:0071732 cellular response to nitric oxide 1/376 16/18722 0.277281303596044 0.478603586385154 CFLAR 1 GO:0072109 glomerular mesangium development 1/376 16/18722 0.277281303596044 0.478603586385154 CFLAR 1 GO:0072283 metanephric renal vesicle morphogenesis 1/376 16/18722 0.277281303596044 0.478603586385154 STAT1 1 GO:0090231 regulation of spindle checkpoint 1/376 16/18722 0.277281303596044 0.478603586385154 DUSP1 1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 1/376 16/18722 0.277281303596044 0.478603586385154 DUSP1 1 GO:0090336 positive regulation of brown fat cell differentiation 1/376 16/18722 0.277281303596044 0.478603586385154 PIM1 1 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane 1/376 16/18722 0.277281303596044 0.478603586385154 VAMP2 1 GO:1901163 regulation of trophoblast cell migration 1/376 16/18722 0.277281303596044 0.478603586385154 ARHGDIB 1 GO:1901201 regulation of extracellular matrix assembly 1/376 16/18722 0.277281303596044 0.478603586385154 TGFB1 1 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1/376 16/18722 0.277281303596044 0.478603586385154 CD44 1 GO:1902306 negative regulation of sodium ion transmembrane transport 1/376 16/18722 0.277281303596044 0.478603586385154 SLC9A3R1 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/376 16/18722 0.277281303596044 0.478603586385154 PLEK 1 GO:1903236 regulation of leukocyte tethering or rolling 1/376 16/18722 0.277281303596044 0.478603586385154 ITGA4 1 GO:1903504 regulation of mitotic spindle checkpoint 1/376 16/18722 0.277281303596044 0.478603586385154 DUSP1 1 GO:1904862 inhibitory synapse assembly 1/376 16/18722 0.277281303596044 0.478603586385154 SEMA4D 1 GO:1904948 midbrain dopaminergic neuron differentiation 1/376 16/18722 0.277281303596044 0.478603586385154 NR4A2 1 GO:2001044 regulation of integrin-mediated signaling pathway 1/376 16/18722 0.277281303596044 0.478603586385154 FLNA 1 GO:2001224 positive regulation of neuron migration 1/376 16/18722 0.277281303596044 0.478603586385154 FLNA 1 GO:0009746 response to hexose 6/376 219/18722 0.278125710762736 0.479463101657631 TXNIP/CYBA/LGALS1/UCP2/VAMP2/XBP1 6 GO:0034764 positive regulation of transmembrane transport 6/376 219/18722 0.278125710762736 0.479463101657631 TMSB4X/XCL1/CALM1/FLNA/PIK3R1/SLC9A3R1 6 GO:0043588 skin development 7/376 263/18722 0.278150465168091 0.479463101657631 TXNIP/LTB/TNF/STK4/ZFP36/PRKCH/ROCK1 7 GO:0006997 nucleus organization 4/376 133/18722 0.27852049712427 0.479887472813049 ETS1/SYNE1/SUN2/SF1 4 GO:0051960 regulation of nervous system development 11/376 443/18722 0.278936706692433 0.48039099485919 CST7/B2M/TNF/CXCR4/TGFB1/ID2/SEMA4D/PRKCH/SORL1/MACF1/ACTR2 11 GO:0010634 positive regulation of epithelial cell migration 5/376 176/18722 0.279767690109689 0.481608084928941 TMSB4X/ETS1/TGFB1/PFN1/GLIPR2 5 GO:0010718 positive regulation of epithelial to mesenchymal transition 2/376 52/18722 0.280711399895921 0.482375465453079 TGFB1/GLIPR2 2 GO:0032206 positive regulation of telomere maintenance 2/376 52/18722 0.280711399895921 0.482375465453079 ATM/ATRX 2 GO:0043277 apoptotic cell clearance 2/376 52/18722 0.280711399895921 0.482375465453079 RAC2/TYROBP 2 GO:0045103 intermediate filament-based process 2/376 52/18722 0.280711399895921 0.482375465453079 VIM/MACF1 2 GO:0015833 peptide transport 7/376 264/18722 0.28127834892999 0.483135461925404 CCL5/TNF/TAP1/RAB8B/UCP2/SLC9A3R1/TAPBP 7 GO:1903312 negative regulation of mRNA metabolic process 3/376 92/18722 0.281630121890674 0.483311214493516 ZFP36/PABPC1/SRSF7 3 GO:1903351 cellular response to dopamine 3/376 92/18722 0.281630121890674 0.483311214493516 GNG2/FLNA/SLC9A3R1 3 GO:0008277 regulation of G protein-coupled receptor signaling pathway 4/376 134/18722 0.282995209079381 0.485224086363982 CCL5/PLEK/RGS1/ROCK1 4 GO:0098727 maintenance of cell number 4/376 134/18722 0.282995209079381 0.485224086363982 ZFP36L2/LBH/STAT3/DDX6 4 GO:0030324 lung development 5/376 177/18722 0.283633944309786 0.485637504402486 KLF2/HOPX/TNF/YWHAZ/CDC42 5 GO:0071453 cellular response to oxygen levels 5/376 177/18722 0.283633944309786 0.485637504402486 MALAT1/RORA/CARD16/CFLAR/HP1BP3 5 GO:0071466 cellular response to xenobiotic stimulus 5/376 177/18722 0.283633944309786 0.485637504402486 RORA/CXCR4/RAP1B/GUK1/PPP1R12A 5 GO:0010975 regulation of neuron projection development 11/376 445/18722 0.28373762837864 0.485637504402486 B2M/FYN/VIM/FLNA/RAB29/CFL1/SEMA4D/LGALS1/MACF1/ACTR2/CFLAR 11 GO:0034765 regulation of ion transmembrane transport 12/376 491/18722 0.284458202809032 0.486655865732891 TMSB4X/XCL1/CORO1A/FYN/CYBA/CALM1/FXYD5/FLNA/VAMP2/SLC9A3R1/PTPN6/CLIC1 12 GO:0032409 regulation of transporter activity 8/376 310/18722 0.285566433528116 0.488336244449007 TMSB4X/CALM1/FXYD5/ACTB/KMT2A/VAMP2/SLC9A3R1/PIM1 8 GO:0007589 body fluid secretion 3/376 93/18722 0.287103993061133 0.489505286235857 CYBA/XBP1/APRT 3 GO:0045132 meiotic chromosome segregation 3/376 93/18722 0.287103993061133 0.489505286235857 ACTR3/ACTR2/CENPC 3 GO:0090398 cellular senescence 3/376 93/18722 0.287103993061133 0.489505286235857 B2M/ATM/ID2 3 GO:0097306 cellular response to alcohol 3/376 93/18722 0.287103993061133 0.489505286235857 KLF2/GNG2/PTGER4 3 GO:1903350 response to dopamine 3/376 93/18722 0.287103993061133 0.489505286235857 GNG2/FLNA/SLC9A3R1 3 GO:0006109 regulation of carbohydrate metabolic process 5/376 178/18722 0.287510457393368 0.489505286235857 PLEK/RORA/DDIT4/TGFB1/STAT3 5 GO:0008347 glial cell migration 2/376 53/18722 0.288175025664261 0.489505286235857 CCL3/SUN2 2 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 2/376 53/18722 0.288175025664261 0.489505286235857 CCL5/PLEK 2 GO:0001936 regulation of endothelial cell proliferation 5/376 179/18722 0.291396747491753 0.489505286235857 CYBA/TNF/ITGA4/STAT1/STAT3 5 GO:0006895 Golgi to endosome transport 1/376 17/18722 0.291808312568988 0.489505286235857 VPS13C 1 GO:0007625 grooming behavior 1/376 17/18722 0.291808312568988 0.489505286235857 APRT 1 GO:0008334 histone mRNA metabolic process 1/376 17/18722 0.291808312568988 0.489505286235857 ATM 1 GO:0009084 glutamine family amino acid biosynthetic process 1/376 17/18722 0.291808312568988 0.489505286235857 GLS 1 GO:0010224 response to UV-B 1/376 17/18722 0.291808312568988 0.489505286235857 CRIP1 1 GO:0021692 cerebellar Purkinje cell layer morphogenesis 1/376 17/18722 0.291808312568988 0.489505286235857 RORA 1 GO:0021924 cell proliferation in external granule layer 1/376 17/18722 0.291808312568988 0.489505286235857 RORA 1 GO:0021930 cerebellar granule cell precursor proliferation 1/376 17/18722 0.291808312568988 0.489505286235857 RORA 1 GO:0030002 cellular anion homeostasis 1/376 17/18722 0.291808312568988 0.489505286235857 SLC9A3R1 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/376 17/18722 0.291808312568988 0.489505286235857 LEPROTL1 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/376 17/18722 0.291808312568988 0.489505286235857 RASGRP1 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/376 17/18722 0.291808312568988 0.489505286235857 RASGRP1 1 GO:0034349 glial cell apoptotic process 1/376 17/18722 0.291808312568988 0.489505286235857 PRKCH 1 GO:0036035 osteoclast development 1/376 17/18722 0.291808312568988 0.489505286235857 TYROBP 1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process 1/376 17/18722 0.291808312568988 0.489505286235857 ATM 1 GO:0042753 positive regulation of circadian rhythm 1/376 17/18722 0.291808312568988 0.489505286235857 RORA 1 GO:0043117 positive regulation of vascular permeability 1/376 17/18722 0.291808312568988 0.489505286235857 TGFB1 1 GO:0043968 histone H2A acetylation 1/376 17/18722 0.291808312568988 0.489505286235857 EPC1 1 GO:0046068 cGMP metabolic process 1/376 17/18722 0.291808312568988 0.489505286235857 RORA 1 GO:0051797 regulation of hair follicle development 1/376 17/18722 0.291808312568988 0.489505286235857 TNF 1 GO:0060263 regulation of respiratory burst 1/376 17/18722 0.291808312568988 0.489505286235857 RAC2 1 GO:0061450 trophoblast cell migration 1/376 17/18722 0.291808312568988 0.489505286235857 ARHGDIB 1 GO:0070206 protein trimerization 1/376 17/18722 0.291808312568988 0.489505286235857 ALOX5AP 1 GO:0070293 renal absorption 1/376 17/18722 0.291808312568988 0.489505286235857 SLC9A3R1 1 GO:0070593 dendrite self-avoidance 1/376 17/18722 0.291808312568988 0.489505286235857 EMB 1 GO:0072673 lamellipodium morphogenesis 1/376 17/18722 0.291808312568988 0.489505286235857 CD44 1 GO:0090083 regulation of inclusion body assembly 1/376 17/18722 0.291808312568988 0.489505286235857 SORL1 1 GO:0090399 replicative senescence 1/376 17/18722 0.291808312568988 0.489505286235857 ATM 1 GO:0090713 immunological memory process 1/376 17/18722 0.291808312568988 0.489505286235857 CD81 1 GO:1900034 regulation of cellular response to heat 1/376 17/18722 0.291808312568988 0.489505286235857 ATM 1 GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II 1/376 17/18722 0.291808312568988 0.489505286235857 TGFB1 1 GO:1903540 establishment of protein localization to postsynaptic membrane 1/376 17/18722 0.291808312568988 0.489505286235857 VAMP2 1 GO:1904262 negative regulation of TORC1 signaling 1/376 17/18722 0.291808312568988 0.489505286235857 ATM 1 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 1/376 17/18722 0.291808312568988 0.489505286235857 STAT1 1 GO:2000811 negative regulation of anoikis 1/376 17/18722 0.291808312568988 0.489505286235857 MCL1 1 GO:0043401 steroid hormone mediated signaling pathway 4/376 136/18722 0.291976506316836 0.489575491985174 DDX5/LBH/PRMT2/DDX17 4 GO:0014020 primary neural tube formation 3/376 94/18722 0.292586159448395 0.490173526961751 TGFB1/PRKACB/PFN1 3 GO:1990830 cellular response to leukemia inhibitory factor 3/376 94/18722 0.292586159448395 0.490173526961751 SRSF7/EIF4A2/NCL 3 GO:0007033 vacuole organization 5/376 180/18722 0.295292334674145 0.493991127349192 CORO1A/PIP4K2A/LAPTM5/LYST/GNPTAB 5 GO:0032984 protein-containing complex disassembly 6/376 224/18722 0.295417694236246 0.493991127349192 PLEK/TNF/CALM1/DDIT4/CFL1/KIF2A 6 GO:0006584 catecholamine metabolic process 2/376 54/18722 0.295629786922007 0.493991127349192 ITGB2/NR4A2 2 GO:0009712 catechol-containing compound metabolic process 2/376 54/18722 0.295629786922007 0.493991127349192 ITGB2/NR4A2 2 GO:0010524 positive regulation of calcium ion transport into cytosol 2/376 54/18722 0.295629786922007 0.493991127349192 XCL1/CALM1 2 GO:2000300 regulation of synaptic vesicle exocytosis 2/376 54/18722 0.295629786922007 0.493991127349192 CALM1/RAP1B 2 GO:0030879 mammary gland development 4/376 137/18722 0.296481615508193 0.495200974178555 LBH/ID2/XBP1/APRT 4 GO:0060249 anatomical structure homeostasis 8/376 314/18722 0.29723390593518 0.49624359564792 B2M/RAC2/CORO1A/MBP/TNFAIP3/ACTB/CSK/ACTG1 8 GO:1990823 response to leukemia inhibitory factor 3/376 95/18722 0.298075344181727 0.497434090742545 SRSF7/EIF4A2/NCL 3 GO:0034284 response to monosaccharide 6/376 225/18722 0.29890218940324 0.498599218225379 TXNIP/CYBA/LGALS1/UCP2/VAMP2/XBP1 6 GO:0030323 respiratory tube development 5/376 181/18722 0.299196741084539 0.498875805379771 KLF2/HOPX/TNF/YWHAZ/CDC42 5 GO:0000724 double-strand break repair via homologous recombination 4/376 138/18722 0.300995391606394 0.499966618573126 WAS/TERF2IP/SAMHD1/ACTR2 4 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 4/376 138/18722 0.300995391606394 0.499966618573126 PTPN22/RASSF5/LAPTM5/CBLB 4 GO:0003179 heart valve morphogenesis 2/376 55/18722 0.303073035314228 0.499966618573126 TGFB1/ROCK1 2 GO:0006414 translational elongation 2/376 55/18722 0.303073035314228 0.499966618573126 EEF1D/EEF1B2 2 GO:0048016 inositol phosphate-mediated signaling 2/376 55/18722 0.303073035314228 0.499966618573126 TBC1D10C/TNF 2 GO:0098900 regulation of action potential 2/376 55/18722 0.303073035314228 0.499966618573126 CALM1/FLNA 2 GO:0009260 ribonucleotide biosynthetic process 5/376 182/18722 0.303109491074958 0.499966618573126 TMSB4X/TGFB1/STAT3/GUK1/APRT 5 GO:0010769 regulation of cell morphogenesis involved in differentiation 3/376 96/18722 0.303570292791769 0.499966618573126 FLNA/CDC42/ACTR2 3 GO:0034620 cellular response to unfolded protein 3/376 96/18722 0.303570292791769 0.499966618573126 PIK3R1/XBP1/PPP1R15A 3 GO:0002076 osteoblast development 1/376 18/18722 0.306044082388505 0.499966618573126 JUND 1 GO:0002501 peptide antigen assembly with MHC protein complex 1/376 18/18722 0.306044082388505 0.499966618573126 B2M 1 GO:0006625 protein targeting to peroxisome 1/376 18/18722 0.306044082388505 0.499966618573126 RAB8B 1 GO:0007549 dosage compensation 1/376 18/18722 0.306044082388505 0.499966618573126 XIST 1 GO:0010985 negative regulation of lipoprotein particle clearance 1/376 18/18722 0.306044082388505 0.499966618573126 CSK 1 GO:0021534 cell proliferation in hindbrain 1/376 18/18722 0.306044082388505 0.499966618573126 RORA 1 GO:0030206 chondroitin sulfate biosynthetic process 1/376 18/18722 0.306044082388505 0.499966618573126 CHST12 1 GO:0030730 sequestering of triglyceride 1/376 18/18722 0.306044082388505 0.499966618573126 TNF 1 GO:0031643 positive regulation of myelination 1/376 18/18722 0.306044082388505 0.499966618573126 CST7 1 GO:0031649 heat generation 1/376 18/18722 0.306044082388505 0.499966618573126 TNF 1 GO:0034162 toll-like receptor 9 signaling pathway 1/376 18/18722 0.306044082388505 0.499966618573126 PTPN22 1 GO:0034587 piRNA metabolic process 1/376 18/18722 0.306044082388505 0.499966618573126 MYBL1 1 GO:0035372 protein localization to microtubule 1/376 18/18722 0.306044082388505 0.499966618573126 ABHD17A 1 GO:0036499 PERK-mediated unfolded protein response 1/376 18/18722 0.306044082388505 0.499966618573126 PPP1R15A 1 GO:0042790 nucleolar large rRNA transcription by RNA polymerase I 1/376 18/18722 0.306044082388505 0.499966618573126 NCL 1 GO:0043217 myelin maintenance 1/376 18/18722 0.306044082388505 0.499966618573126 CXCR4 1 GO:0046040 IMP metabolic process 1/376 18/18722 0.306044082388505 0.499966618573126 APRT 1 GO:0046112 nucleobase biosynthetic process 1/376 18/18722 0.306044082388505 0.499966618573126 APRT 1 GO:0051382 kinetochore assembly 1/376 18/18722 0.306044082388505 0.499966618573126 CENPC 1 GO:0051782 negative regulation of cell division 1/376 18/18722 0.306044082388505 0.499966618573126 TXNIP 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/376 18/18722 0.306044082388505 0.499966618573126 TGFB1 1 GO:0060546 negative regulation of necroptotic process 1/376 18/18722 0.306044082388505 0.499966618573126 CASP8 1 GO:0060716 labyrinthine layer blood vessel development 1/376 18/18722 0.306044082388505 0.499966618573126 JUNB 1 GO:0060749 mammary gland alveolus development 1/376 18/18722 0.306044082388505 0.499966618573126 ID2 1 GO:0061377 mammary gland lobule development 1/376 18/18722 0.306044082388505 0.499966618573126 ID2 1 GO:0072234 metanephric nephron tubule development 1/376 18/18722 0.306044082388505 0.499966618573126 STAT1 1 GO:0072662 protein localization to peroxisome 1/376 18/18722 0.306044082388505 0.499966618573126 RAB8B 1 GO:0072663 establishment of protein localization to peroxisome 1/376 18/18722 0.306044082388505 0.499966618573126 RAB8B 1 GO:0090493 catecholamine uptake 1/376 18/18722 0.306044082388505 0.499966618573126 ACTB 1 GO:0098877 neurotransmitter receptor transport to plasma membrane 1/376 18/18722 0.306044082388505 0.499966618573126 VAMP2 1 GO:0110154 RNA decapping 1/376 18/18722 0.306044082388505 0.499966618573126 ZFP36 1 GO:1900225 regulation of NLRP3 inflammasome complex assembly 1/376 18/18722 0.306044082388505 0.499966618573126 GBP5 1 GO:1900424 regulation of defense response to bacterium 1/376 18/18722 0.306044082388505 0.499966618573126 CYBA 1 GO:1902170 cellular response to reactive nitrogen species 1/376 18/18722 0.306044082388505 0.499966618573126 CFLAR 1 GO:1902683 regulation of receptor localization to synapse 1/376 18/18722 0.306044082388505 0.499966618573126 TYROBP 1 GO:1903209 positive regulation of oxidative stress-induced cell death 1/376 18/18722 0.306044082388505 0.499966618573126 MCL1 1 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 1/376 18/18722 0.306044082388505 0.499966618573126 PIM1 1 GO:2000641 regulation of early endosome to late endosome transport 1/376 18/18722 0.306044082388505 0.499966618573126 MSN 1 GO:2001135 regulation of endocytic recycling 1/376 18/18722 0.306044082388505 0.499966618573126 SORL1 1 GO:0010596 negative regulation of endothelial cell migration 3/376 97/18722 0.309069773333722 0.504484149818102 TNF/TGFB1/SP100 3 GO:0120162 positive regulation of cold-induced thermogenesis 3/376 97/18722 0.309069773333722 0.504484149818102 PLAC8/CXCR4/UCP2 3 GO:0000725 recombinational repair 4/376 140/18722 0.310046063876897 0.50469637101737 WAS/TERF2IP/SAMHD1/ACTR2 4 GO:0030177 positive regulation of Wnt signaling pathway 4/376 140/18722 0.310046063876897 0.50469637101737 TGFB1/TNFAIP3/ZEB2/MACF1 4 GO:0050768 negative regulation of neurogenesis 4/376 140/18722 0.310046063876897 0.50469637101737 B2M/TNF/SEMA4D/SORL1 4 GO:0010518 positive regulation of phospholipase activity 2/376 56/18722 0.310502231872364 0.50469637101737 CCL5/TXK 2 GO:0022029 telencephalon cell migration 2/376 56/18722 0.310502231872364 0.50469637101737 CXCR4/SUN2 2 GO:0043470 regulation of carbohydrate catabolic process 2/376 56/18722 0.310502231872364 0.50469637101737 DDIT4/STAT3 2 GO:0048255 mRNA stabilization 2/376 56/18722 0.310502231872364 0.50469637101737 ZFP36/PABPC1 2 GO:0051784 negative regulation of nuclear division 2/376 56/18722 0.310502231872364 0.50469637101737 ATM/DUSP1 2 GO:0098781 ncRNA transcription 2/376 56/18722 0.310502231872364 0.50469637101737 GTF3A/NCL 2 GO:1904645 response to amyloid-beta 2/376 56/18722 0.310502231872364 0.50469637101737 FYN/ITGA4 2 GO:0032642 regulation of chemokine production 3/376 98/18722 0.314572576486597 0.507695609113754 MBP/TNF/PYCARD 3 GO:0070301 cellular response to hydrogen peroxide 3/376 98/18722 0.314572576486597 0.507695609113754 ETS1/KLF2/TNFAIP3 3 GO:0051896 regulation of protein kinase B signaling 5/376 185/18722 0.314893081863729 0.507695609113754 TNF/CCL3/TGFB1/MTDH/SLC9A3R1 5 GO:0140013 meiotic nuclear division 5/376 185/18722 0.314893081863729 0.507695609113754 MYBL1/ATM/ACTR3/ACTR2/CENPC 5 GO:0009416 response to light stimulus 8/376 320/18722 0.314937880235231 0.507695609113754 CRIP1/CDKN2D/FOS/ID2/JUND/DUSP1/PIK3R1/CARD16 8 GO:0002011 morphogenesis of an epithelial sheet 2/376 57/18722 0.317914943708878 0.507695609113754 CD44/FLNA 2 GO:0006611 protein export from nucleus 2/376 57/18722 0.317914943708878 0.507695609113754 TGFB1/SP100 2 GO:0010883 regulation of lipid storage 2/376 57/18722 0.317914943708878 0.507695609113754 TNF/NFKBIA 2 GO:0016447 somatic recombination of immunoglobulin gene segments 2/376 57/18722 0.317914943708878 0.507695609113754 PTPRC/TGFB1 2 GO:0030219 megakaryocyte differentiation 2/376 57/18722 0.317914943708878 0.507695609113754 PIP4K2A/PTPN6 2 GO:0051155 positive regulation of striated muscle cell differentiation 2/376 57/18722 0.317914943708878 0.507695609113754 HOPX/TGFB1 2 GO:0097120 receptor localization to synapse 2/376 57/18722 0.317914943708878 0.507695609113754 TYROBP/VAMP2 2 GO:1900024 regulation of substrate adhesion-dependent cell spreading 2/376 57/18722 0.317914943708878 0.507695609113754 FLNA/CDC42 2 GO:1902017 regulation of cilium assembly 2/376 57/18722 0.317914943708878 0.507695609113754 CYLD/ODF2L 2 GO:0007009 plasma membrane organization 4/376 142/18722 0.319122831091915 0.507695609113754 PTPRC/CXCR4/BIN2/SLC9A3R1 4 GO:0000028 ribosomal small subunit assembly 1/376 19/18722 0.319994436591986 0.507695609113754 RPS27 1 GO:0002281 macrophage activation involved in immune response 1/376 19/18722 0.319994436591986 0.507695609113754 TYROBP 1 GO:0006144 purine nucleobase metabolic process 1/376 19/18722 0.319994436591986 0.507695609113754 APRT 1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1/376 19/18722 0.319994436591986 0.507695609113754 ATM 1 GO:0007039 protein catabolic process in the vacuole 1/376 19/18722 0.319994436591986 0.507695609113754 CD81 1 GO:0007530 sex determination 1/376 19/18722 0.319994436591986 0.507695609113754 SF1 1 GO:0009168 purine ribonucleoside monophosphate biosynthetic process 1/376 19/18722 0.319994436591986 0.507695609113754 APRT 1 GO:0010744 positive regulation of macrophage derived foam cell differentiation 1/376 19/18722 0.319994436591986 0.507695609113754 PRKCH 1 GO:0010759 positive regulation of macrophage chemotaxis 1/376 19/18722 0.319994436591986 0.507695609113754 CCL5 1 GO:0010829 negative regulation of glucose transmembrane transport 1/376 19/18722 0.319994436591986 0.507695609113754 TNF 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/376 19/18722 0.319994436591986 0.507695609113754 SLC9A3R1 1 GO:0030011 maintenance of cell polarity 1/376 19/18722 0.319994436591986 0.507695609113754 SLC9A3R1 1 GO:0030050 vesicle transport along actin filament 1/376 19/18722 0.319994436591986 0.507695609113754 MYO1F 1 GO:0030220 platelet formation 1/376 19/18722 0.319994436591986 0.507695609113754 PTPN6 1 GO:0032011 ARF protein signal transduction 1/376 19/18722 0.319994436591986 0.507695609113754 CYTH1 1 GO:0032012 regulation of ARF protein signal transduction 1/376 19/18722 0.319994436591986 0.507695609113754 CYTH1 1 GO:0032616 interleukin-13 production 1/376 19/18722 0.319994436591986 0.507695609113754 HLA-E 1 GO:0032656 regulation of interleukin-13 production 1/376 19/18722 0.319994436591986 0.507695609113754 HLA-E 1 GO:0036344 platelet morphogenesis 1/376 19/18722 0.319994436591986 0.507695609113754 PTPN6 1 GO:0036498 IRE1-mediated unfolded protein response 1/376 19/18722 0.319994436591986 0.507695609113754 XBP1 1 GO:0043652 engulfment of apoptotic cell 1/376 19/18722 0.319994436591986 0.507695609113754 RAC2 1 GO:0044320 cellular response to leptin stimulus 1/376 19/18722 0.319994436591986 0.507695609113754 STAT3 1 GO:0044546 NLRP3 inflammasome complex assembly 1/376 19/18722 0.319994436591986 0.507695609113754 GBP5 1 GO:0045603 positive regulation of endothelial cell differentiation 1/376 19/18722 0.319994436591986 0.507695609113754 BTG1 1 GO:0045618 positive regulation of keratinocyte differentiation 1/376 19/18722 0.319994436591986 0.507695609113754 PRKCH 1 GO:0046033 AMP metabolic process 1/376 19/18722 0.319994436591986 0.507695609113754 APRT 1 GO:0046782 regulation of viral transcription 1/376 19/18722 0.319994436591986 0.507695609113754 ZFP36 1 GO:0046794 transport of virus 1/376 19/18722 0.319994436591986 0.507695609113754 BST2 1 GO:0050961 detection of temperature stimulus involved in sensory perception 1/376 19/18722 0.319994436591986 0.507695609113754 CXCR4 1 GO:0060216 definitive hemopoiesis 1/376 19/18722 0.319994436591986 0.507695609113754 ZFP36L2 1 GO:0061323 cell proliferation involved in heart morphogenesis 1/376 19/18722 0.319994436591986 0.507695609113754 PIM1 1 GO:0062099 negative regulation of programmed necrotic cell death 1/376 19/18722 0.319994436591986 0.507695609113754 CASP8 1 GO:0072074 kidney mesenchyme development 1/376 19/18722 0.319994436591986 0.507695609113754 STAT1 1 GO:0072077 renal vesicle morphogenesis 1/376 19/18722 0.319994436591986 0.507695609113754 STAT1 1 GO:0086014 atrial cardiac muscle cell action potential 1/376 19/18722 0.319994436591986 0.507695609113754 FLNA 1 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 1/376 19/18722 0.319994436591986 0.507695609113754 FLNA 1 GO:0086066 atrial cardiac muscle cell to AV node cell communication 1/376 19/18722 0.319994436591986 0.507695609113754 FLNA 1 GO:1901659 glycosyl compound biosynthetic process 1/376 19/18722 0.319994436591986 0.507695609113754 APRT 1 GO:1901881 positive regulation of protein depolymerization 1/376 19/18722 0.319994436591986 0.507695609113754 PLEK 1 GO:1903975 regulation of glial cell migration 1/376 19/18722 0.319994436591986 0.507695609113754 CCL3 1 GO:2000251 positive regulation of actin cytoskeleton reorganization 1/376 19/18722 0.319994436591986 0.507695609113754 CDC42 1 GO:0032602 chemokine production 3/376 99/18722 0.320077515629652 0.507695609113754 MBP/TNF/PYCARD 3 GO:0051153 regulation of striated muscle cell differentiation 3/376 99/18722 0.320077515629652 0.507695609113754 HOPX/TGFB1/XBP1 3 GO:0060996 dendritic spine development 3/376 99/18722 0.320077515629652 0.507695609113754 CFL1/CDC42/ACTR2 3 GO:0009161 ribonucleoside monophosphate metabolic process 2/376 58/18722 0.325308840799972 0.514939443668256 GUK1/APRT 2 GO:0010574 regulation of vascular endothelial growth factor production 2/376 58/18722 0.325308840799972 0.514939443668256 RORA/TGFB1 2 GO:0086065 cell communication involved in cardiac conduction 2/376 58/18722 0.325308840799972 0.514939443668256 CALM1/FLNA 2 GO:1902808 positive regulation of cell cycle G1/S phase transition 2/376 58/18722 0.325308840799972 0.514939443668256 CCND2/KMT2E 2 GO:2000649 regulation of sodium ion transmembrane transporter activity 2/376 58/18722 0.325308840799972 0.514939443668256 FXYD5/SLC9A3R1 2 GO:0019218 regulation of steroid metabolic process 3/376 100/18722 0.325583426897071 0.515163650153593 RORA/TNF/SF1 3 GO:0022898 regulation of transmembrane transporter activity 7/376 278/18722 0.325872205762204 0.515410121358588 TMSB4X/CALM1/FXYD5/ACTB/VAMP2/SLC9A3R1/PIM1 7 GO:0008544 epidermis development 8/376 324/18722 0.326857045359029 0.516756854657787 TXNIP/TNF/STK4/WAS/ZFP36/PRKCH/SLC9A3R1/ROCK1 8 GO:0106106 cold-induced thermogenesis 4/376 144/18722 0.328220115835094 0.518217312618236 PLAC8/CXCR4/UCP2/LNPEP 4 GO:0120161 regulation of cold-induced thermogenesis 4/376 144/18722 0.328220115835094 0.518217312618236 PLAC8/CXCR4/UCP2/LNPEP 4 GO:0048588 developmental cell growth 6/376 234/18722 0.330578151041509 0.518217312618236 CXCR4/ITGA4/SEMA4D/AKAP13/MACF1/PRMT2 6 GO:0046939 nucleotide phosphorylation 3/376 101/18722 0.331089169211906 0.518217312618236 DDIT4/STAT3/GUK1 3 GO:0001836 release of cytochrome c from mitochondria 2/376 59/18722 0.332681692854189 0.518217312618236 JUN/PYCARD 2 GO:0021885 forebrain cell migration 2/376 59/18722 0.332681692854189 0.518217312618236 CXCR4/SUN2 2 GO:0030042 actin filament depolymerization 2/376 59/18722 0.332681692854189 0.518217312618236 PLEK/CFL1 2 GO:0032768 regulation of monooxygenase activity 2/376 59/18722 0.332681692854189 0.518217312618236 TNF/CALM1 2 GO:0046324 regulation of glucose import 2/376 59/18722 0.332681692854189 0.518217312618236 TNF/PIK3R1 2 GO:0048278 vesicle docking 2/376 59/18722 0.332681692854189 0.518217312618236 PLEK/RAB8B 2 GO:0051568 histone H3-K4 methylation 2/376 59/18722 0.332681692854189 0.518217312618236 KMT2A/KMT2E 2 GO:0071806 protein transmembrane transport 2/376 59/18722 0.332681692854189 0.518217312618236 TOMM7/MCL1 2 GO:0043524 negative regulation of neuron apoptotic process 4/376 145/18722 0.33277474192716 0.518217312618236 CORO1A/FYN/NR4A2/BTG2 4 GO:0051961 negative regulation of nervous system development 4/376 145/18722 0.33277474192716 0.518217312618236 B2M/TNF/SEMA4D/SORL1 4 GO:0061351 neural precursor cell proliferation 4/376 145/18722 0.33277474192716 0.518217312618236 RORA/FLNA/ID2/BTG2 4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle 1/376 20/18722 0.333665082576129 0.518217312618236 ID2 1 GO:0003159 morphogenesis of an endothelium 1/376 20/18722 0.333665082576129 0.518217312618236 CXCR4 1 GO:0006607 NLS-bearing protein import into nucleus 1/376 20/18722 0.333665082576129 0.518217312618236 CBLB 1 GO:0006896 Golgi to vacuole transport 1/376 20/18722 0.333665082576129 0.518217312618236 LAPTM5 1 GO:0009110 vitamin biosynthetic process 1/376 20/18722 0.333665082576129 0.518217312618236 TNF 1 GO:0009713 catechol-containing compound biosynthetic process 1/376 20/18722 0.333665082576129 0.518217312618236 NR4A2 1 GO:0010523 negative regulation of calcium ion transport into cytosol 1/376 20/18722 0.333665082576129 0.518217312618236 CALM1 1 GO:0010893 positive regulation of steroid biosynthetic process 1/376 20/18722 0.333665082576129 0.518217312618236 TNF 1 GO:0015919 peroxisomal membrane transport 1/376 20/18722 0.333665082576129 0.518217312618236 RAB8B 1 GO:0030150 protein import into mitochondrial matrix 1/376 20/18722 0.333665082576129 0.518217312618236 TOMM7 1 GO:0042359 vitamin D metabolic process 1/376 20/18722 0.333665082576129 0.518217312618236 TNF 1 GO:0042423 catecholamine biosynthetic process 1/376 20/18722 0.333665082576129 0.518217312618236 NR4A2 1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 1/376 20/18722 0.333665082576129 0.518217312618236 ITM2A 1 GO:0043984 histone H4-K16 acetylation 1/376 20/18722 0.333665082576129 0.518217312618236 KMT2A 1 GO:0045063 T-helper 1 cell differentiation 1/376 20/18722 0.333665082576129 0.518217312618236 SPN 1 GO:0048025 negative regulation of mRNA splicing, via spliceosome 1/376 20/18722 0.333665082576129 0.518217312618236 SRSF7 1 GO:0048670 regulation of collateral sprouting 1/376 20/18722 0.333665082576129 0.518217312618236 SEMA4D 1 GO:0060231 mesenchymal to epithelial transition 1/376 20/18722 0.333665082576129 0.518217312618236 STAT1 1 GO:0061003 positive regulation of dendritic spine morphogenesis 1/376 20/18722 0.333665082576129 0.518217312618236 ACTR2 1 GO:0061154 endothelial tube morphogenesis 1/376 20/18722 0.333665082576129 0.518217312618236 CXCR4 1 GO:0071731 response to nitric oxide 1/376 20/18722 0.333665082576129 0.518217312618236 CFLAR 1 GO:0072087 renal vesicle development 1/376 20/18722 0.333665082576129 0.518217312618236 STAT1 1 GO:0097320 plasma membrane tubulation 1/376 20/18722 0.333665082576129 0.518217312618236 BIN2 1 GO:0140632 inflammasome complex assembly 1/376 20/18722 0.333665082576129 0.518217312618236 GBP5 1 GO:1901386 negative regulation of voltage-gated calcium channel activity 1/376 20/18722 0.333665082576129 0.518217312618236 CALM1 1 GO:1902004 positive regulation of amyloid-beta formation 1/376 20/18722 0.333665082576129 0.518217312618236 TNF 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/376 20/18722 0.333665082576129 0.518217312618236 XBP1 1 GO:1990182 exosomal secretion 1/376 20/18722 0.333665082576129 0.518217312618236 RAB27A 1 GO:2000678 negative regulation of transcription regulatory region DNA binding 1/376 20/18722 0.333665082576129 0.518217312618236 TMSB4X 1 GO:0046390 ribose phosphate biosynthetic process 5/376 190/18722 0.33465561010509 0.519339402946426 TMSB4X/TGFB1/STAT3/GUK1/APRT 5 GO:0099111 microtubule-based transport 5/376 190/18722 0.33465561010509 0.519339402946426 RASGRP1/SUN2/OFD1/SLC9A3R1/CDC42 5 GO:0098813 nuclear chromosome segregation 7/376 281/18722 0.335584290113139 0.520572107361254 ATM/DUSP1/ACTR3/CDC42/ACTR2/ATRX/CENPC 7 GO:0007517 muscle organ development 8/376 327/18722 0.335848507857674 0.520773496578025 DDX5/TGFB1/FOS/XBP1/BTG2/CFLAR/VAMP5/DDX17 8 GO:0045833 negative regulation of lipid metabolic process 3/376 102/18722 0.336593624300287 0.521511513060221 TNF/PIP4K2A/SORL1 3 GO:0062014 negative regulation of small molecule metabolic process 3/376 102/18722 0.336593624300287 0.521511513060221 PLEK/DDIT4/STAT3 3 GO:0010675 regulation of cellular carbohydrate metabolic process 4/376 146/18722 0.337332460338947 0.522447355640855 PLEK/RORA/DDIT4/STAT3 4 GO:0000209 protein polyubiquitination 6/376 236/18722 0.337679706194858 0.522567436703305 PTPN22/TRIM22/TNFAIP3/UBE2L6/RNF19A/LNPEP 6 GO:0048738 cardiac muscle tissue development 6/376 236/18722 0.337679706194858 0.522567436703305 HOPX/TGFB1/ID2/AKAP13/PIM1/CDC42 6 GO:0006164 purine nucleotide biosynthetic process 5/376 191/18722 0.338622473799362 0.523817199989032 TMSB4X/TGFB1/STAT3/GUK1/APRT 5 GO:0030111 regulation of Wnt signaling pathway 8/376 328/18722 0.338854523137389 0.523966990086744 RNF213/STK4/TGFB1/TNFAIP3/CYLD/ZEB2/SLC9A3R1/MACF1 8 GO:0009620 response to fungus 2/376 60/18722 0.340031366264749 0.524948822420678 GNLY/SPON2 2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 2/376 60/18722 0.340031366264749 0.524948822420678 ATM/TAOK3 2 GO:0030071 regulation of mitotic metaphase/anaphase transition 2/376 60/18722 0.340031366264749 0.524948822420678 ATM/DUSP1 2 GO:1903670 regulation of sprouting angiogenesis 2/376 60/18722 0.340031366264749 0.524948822420678 KLF2/JAK1 2 GO:0016331 morphogenesis of embryonic epithelium 4/376 147/18722 0.341892608282061 0.527185736368967 STK4/TGFB1/PRKACB/PFN1 4 GO:0009135 purine nucleoside diphosphate metabolic process 3/376 103/18722 0.342095696686841 0.527185736368967 DDIT4/STAT3/GUK1 3 GO:0009179 purine ribonucleoside diphosphate metabolic process 3/376 103/18722 0.342095696686841 0.527185736368967 DDIT4/STAT3/GUK1 3 GO:0019233 sensory perception of pain 3/376 103/18722 0.342095696686841 0.527185736368967 FYN/CXCR4/CCL3 3 GO:0048638 regulation of developmental growth 8/376 330/18722 0.344878657237319 0.527185736368967 HOPX/PLAC8/CXCR4/STK4/SEMA4D/PIM1/STAT3/MACF1 8 GO:0051051 negative regulation of transport 11/376 470/18722 0.345532423826215 0.527185736368967 CORO1A/HLA-F/TNF/CALM1/BST2/CNN2/SP100/UCP2/CSK/RAP1B/SLC9A3R1 11 GO:0001935 endothelial cell proliferation 5/376 193/18722 0.346566963458126 0.527185736368967 CYBA/TNF/ITGA4/STAT1/STAT3 5 GO:0002689 negative regulation of leukocyte chemotaxis 1/376 21/18722 0.347061613907076 0.527185736368967 DUSP1 1 GO:0003091 renal water homeostasis 1/376 21/18722 0.347061613907076 0.527185736368967 PRKACB 1 GO:0007063 regulation of sister chromatid cohesion 1/376 21/18722 0.347061613907076 0.527185736368967 ATRX 1 GO:0007252 I-kappaB phosphorylation 1/376 21/18722 0.347061613907076 0.527185736368967 TNF 1 GO:0009127 purine nucleoside monophosphate biosynthetic process 1/376 21/18722 0.347061613907076 0.527185736368967 APRT 1 GO:0010766 negative regulation of sodium ion transport 1/376 21/18722 0.347061613907076 0.527185736368967 SLC9A3R1 1 GO:0010988 regulation of low-density lipoprotein particle clearance 1/376 21/18722 0.347061613907076 0.527185736368967 CSK 1 GO:0019370 leukotriene biosynthetic process 1/376 21/18722 0.347061613907076 0.527185736368967 ALOX5AP 1 GO:0021533 cell differentiation in hindbrain 1/376 21/18722 0.347061613907076 0.527185736368967 RORA 1 GO:0038083 peptidyl-tyrosine autophosphorylation 1/376 21/18722 0.347061613907076 0.527185736368967 TXK 1 GO:0044766 multi-organism transport 1/376 21/18722 0.347061613907076 0.527185736368967 BST2 1 GO:0045655 regulation of monocyte differentiation 1/376 21/18722 0.347061613907076 0.527185736368967 JUN 1 GO:0046128 purine ribonucleoside metabolic process 1/376 21/18722 0.347061613907076 0.527185736368967 APRT 1 GO:0046823 negative regulation of nucleocytoplasmic transport 1/376 21/18722 0.347061613907076 0.527185736368967 SP100 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/376 21/18722 0.347061613907076 0.527185736368967 CXCR4 1 GO:0051767 nitric-oxide synthase biosynthetic process 1/376 21/18722 0.347061613907076 0.527185736368967 STAT1 1 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1/376 21/18722 0.347061613907076 0.527185736368967 STAT1 1 GO:0060117 auditory receptor cell development 1/376 21/18722 0.347061613907076 0.527185736368967 SLC9A3R1 1 GO:0060445 branching involved in salivary gland morphogenesis 1/376 21/18722 0.347061613907076 0.527185736368967 TNF 1 GO:0071498 cellular response to fluid shear stress 1/376 21/18722 0.347061613907076 0.527185736368967 KLF2 1 GO:0072170 metanephric tubule development 1/376 21/18722 0.347061613907076 0.527185736368967 STAT1 1 GO:0072243 metanephric nephron epithelium development 1/376 21/18722 0.347061613907076 0.527185736368967 STAT1 1 GO:0090026 positive regulation of monocyte chemotaxis 1/376 21/18722 0.347061613907076 0.527185736368967 CCL5 1 GO:0097062 dendritic spine maintenance 1/376 21/18722 0.347061613907076 0.527185736368967 FYN 1 GO:0097734 extracellular exosome biogenesis 1/376 21/18722 0.347061613907076 0.527185736368967 RAB27A 1 GO:0150146 cell junction disassembly 1/376 21/18722 0.347061613907076 0.527185736368967 PIK3R1 1 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/376 21/18722 0.347061613907076 0.527185736368967 GZMB 1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/376 21/18722 0.347061613907076 0.527185736368967 CD44 1 GO:1902259 regulation of delayed rectifier potassium channel activity 1/376 21/18722 0.347061613907076 0.527185736368967 VAMP2 1 GO:1902579 multi-organism localization 1/376 21/18722 0.347061613907076 0.527185736368967 BST2 1 GO:1905209 positive regulation of cardiocyte differentiation 1/376 21/18722 0.347061613907076 0.527185736368967 TGFB1 1 GO:2000178 negative regulation of neural precursor cell proliferation 1/376 21/18722 0.347061613907076 0.527185736368967 BTG2 1 GO:2000291 regulation of myoblast proliferation 1/376 21/18722 0.347061613907076 0.527185736368967 MALAT1 1 GO:2000774 positive regulation of cellular senescence 1/376 21/18722 0.347061613907076 0.527185736368967 B2M 1 GO:0040014 regulation of multicellular organism growth 2/376 61/18722 0.347355821143547 0.527185736368967 PLAC8/STAT3 2 GO:0050994 regulation of lipid catabolic process 2/376 61/18722 0.347355821143547 0.527185736368967 TNF/SORL1 2 GO:0014896 muscle hypertrophy 3/376 104/18722 0.347594313672259 0.527185736368967 CYBA/AKAP13/ROCK1 3 GO:0048608 reproductive structure development 10/376 424/18722 0.347602466173603 0.527185736368967 CRIP1/EOMES/PRDM1/STK4/JUNB/FLNA/CASP8/PTPN6/ATRX/SF1 10 GO:0009411 response to UV 4/376 149/18722 0.351017581780669 0.531948818693818 CRIP1/CDKN2D/PIK3R1/CARD16 4 GO:0016525 negative regulation of angiogenesis 4/376 149/18722 0.351017581780669 0.531948818693818 KLF2/TNF/STAT1/ROCK1 4 GO:0016079 synaptic vesicle exocytosis 3/376 105/18722 0.353088425293887 0.534877892108606 CALM1/VAMP2/RAP1B 3 GO:0030705 cytoskeleton-dependent intracellular transport 5/376 195/18722 0.354522863293064 0.535364548182589 RASGRP1/SUN2/MYO1F/TUBA1A/CDC42 5 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 2/376 62/18722 0.354653108434763 0.535364548182589 ATM/DUSP1 2 GO:0007588 excretion 2/376 62/18722 0.354653108434763 0.535364548182589 SLC9A3R1/MLLT6 2 GO:0045428 regulation of nitric oxide biosynthetic process 2/376 62/18722 0.354653108434763 0.535364548182589 KLF2/TNF 2 GO:0046148 pigment biosynthetic process 2/376 62/18722 0.354653108434763 0.535364548182589 ZEB2/APRT 2 GO:0046847 filopodium assembly 2/376 62/18722 0.354653108434763 0.535364548182589 PIK3R1/CDC42 2 GO:0048663 neuron fate commitment 2/376 62/18722 0.354653108434763 0.535364548182589 ID2/CDC42 2 GO:0060135 maternal process involved in female pregnancy 2/376 62/18722 0.354653108434763 0.535364548182589 PRDM1/JUNB 2 GO:1902750 negative regulation of cell cycle G2/M phase transition 2/376 62/18722 0.354653108434763 0.535364548182589 ATM/TAOK3 2 GO:0140014 mitotic nuclear division 7/376 287/18722 0.35512186101396 0.535863400089212 ATM/FLNA/DUSP1/KIF2A/CDC42/ATRX/CENPC 7 GO:0060047 heart contraction 6/376 241/18722 0.355502357969787 0.536045476443435 HOPX/CELF2/CALM1/CXCR4/FLNA/CDC42 6 GO:0061458 reproductive system development 10/376 427/18722 0.355608754675331 0.536045476443435 CRIP1/EOMES/PRDM1/STK4/JUNB/FLNA/CASP8/PTPN6/ATRX/SF1 10 GO:0031667 response to nutrient levels 11/376 474/18722 0.355657527725438 0.536045476443435 CD3E/CYBA/IFI16/CDKN2D/JUN/ZFP36/STAT1/UCP2/XBP1/SORL1/PIM1 11 GO:0009185 ribonucleoside diphosphate metabolic process 3/376 106/18722 0.358577004270209 0.537027457201176 DDIT4/STAT3/GUK1 3 GO:0043535 regulation of blood vessel endothelial cell migration 4/376 151/18722 0.360144522332129 0.537027457201176 TMSB4X/ETS1/TNF/TGFB1 4 GO:0071333 cellular response to glucose stimulus 4/376 151/18722 0.360144522332129 0.537027457201176 CYBA/LGALS1/UCP2/XBP1 4 GO:1904064 positive regulation of cation transmembrane transport 4/376 151/18722 0.360144522332129 0.537027457201176 TMSB4X/XCL1/CALM1/FLNA 4 GO:2000181 negative regulation of blood vessel morphogenesis 4/376 151/18722 0.360144522332129 0.537027457201176 KLF2/TNF/STAT1/ROCK1 4 GO:0002053 positive regulation of mesenchymal cell proliferation 1/376 22/18722 0.360189512584737 0.537027457201176 STAT1 1 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 1/376 22/18722 0.360189512584737 0.537027457201176 CALM1 1 GO:0021854 hypothalamus development 1/376 22/18722 0.360189512584737 0.537027457201176 ETS1 1 GO:0021904 dorsal/ventral neural tube patterning 1/376 22/18722 0.360189512584737 0.537027457201176 PRKACB 1 GO:0031061 negative regulation of histone methylation 1/376 22/18722 0.360189512584737 0.537027457201176 MLLT6 1 GO:0032069 regulation of nuclease activity 1/376 22/18722 0.360189512584737 0.537027457201176 GZMA 1 GO:0032402 melanosome transport 1/376 22/18722 0.360189512584737 0.537027457201176 RAB27A 1 GO:0032693 negative regulation of interleukin-10 production 1/376 22/18722 0.360189512584737 0.537027457201176 TYROBP 1 GO:0032727 positive regulation of interferon-alpha production 1/376 22/18722 0.360189512584737 0.537027457201176 STAT1 1 GO:0035584 calcium-mediated signaling using intracellular calcium source 1/376 22/18722 0.360189512584737 0.537027457201176 PTPRC 1 GO:0035809 regulation of urine volume 1/376 22/18722 0.360189512584737 0.537027457201176 MLLT6 1 GO:0036120 cellular response to platelet-derived growth factor stimulus 1/376 22/18722 0.360189512584737 0.537027457201176 FYN 1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 1/376 22/18722 0.360189512584737 0.537027457201176 RUNX3 1 GO:0043486 histone exchange 1/376 22/18722 0.360189512584737 0.537027457201176 ANP32E 1 GO:0043574 peroxisomal transport 1/376 22/18722 0.360189512584737 0.537027457201176 RAB8B 1 GO:0045663 positive regulation of myoblast differentiation 1/376 22/18722 0.360189512584737 0.537027457201176 BTG1 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/376 22/18722 0.360189512584737 0.537027457201176 SORL1 1 GO:0048026 positive regulation of mRNA splicing, via spliceosome 1/376 22/18722 0.360189512584737 0.537027457201176 NCL 1 GO:0090280 positive regulation of calcium ion import 1/376 22/18722 0.360189512584737 0.537027457201176 CCL3 1 GO:0140467 integrated stress response signaling 1/376 22/18722 0.360189512584737 0.537027457201176 PPP1R15A 1 GO:1900120 regulation of receptor binding 1/376 22/18722 0.360189512584737 0.537027457201176 B2M 1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 1/376 22/18722 0.360189512584737 0.537027457201176 XBP1 1 GO:2000725 regulation of cardiac muscle cell differentiation 1/376 22/18722 0.360189512584737 0.537027457201176 TGFB1 1 GO:0046902 regulation of mitochondrial membrane permeability 2/376 63/18722 0.361921367106108 0.53878036785869 GZMB/STAT3 2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2/376 63/18722 0.361921367106108 0.53878036785869 XBP1/PPP1R15A 2 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 2/376 63/18722 0.361921367106108 0.53878036785869 ATM/DUSP1 2 GO:1902373 negative regulation of mRNA catabolic process 2/376 63/18722 0.361921367106108 0.53878036785869 ZFP36/PABPC1 2 GO:0042594 response to starvation 5/376 197/18722 0.362486696762338 0.539414727324908 IFI16/JUN/ZFP36/UCP2/XBP1 5 GO:0016358 dendrite development 6/376 243/18722 0.362652191783958 0.539453836146963 CD3E/FYN/CFL1/SEMA4D/CDC42/ACTR2 6 GO:0006275 regulation of DNA replication 3/376 107/18722 0.364059045930037 0.540095253820404 JUN/CDC42/ATRX 3 GO:0008637 apoptotic mitochondrial changes 3/376 107/18722 0.364059045930037 0.540095253820404 GZMB/JUN/PYCARD 3 GO:0010927 cellular component assembly involved in morphogenesis 3/376 107/18722 0.364059045930037 0.540095253820404 AKAP13/ACTG1/CFLAR 3 GO:0032526 response to retinoic acid 3/376 107/18722 0.364059045930037 0.540095253820404 ATM/CDKN2D/DUSP1 3 GO:0071868 cellular response to monoamine stimulus 3/376 107/18722 0.364059045930037 0.540095253820404 GNG2/FLNA/SLC9A3R1 3 GO:0071870 cellular response to catecholamine stimulus 3/376 107/18722 0.364059045930037 0.540095253820404 GNG2/FLNA/SLC9A3R1 3 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 3/376 107/18722 0.364059045930037 0.540095253820404 PYHIN1/LAPTM5/RNF19A 3 GO:0021915 neural tube development 4/376 152/18722 0.36470716031528 0.540436040620157 STK4/TGFB1/PRKACB/PFN1 4 GO:0031056 regulation of histone modification 4/376 152/18722 0.36470716031528 0.540436040620157 KMT2A/KMT2E/MLLT6/ATRX 4 GO:1901343 negative regulation of vasculature development 4/376 152/18722 0.36470716031528 0.540436040620157 KLF2/TNF/STAT1/ROCK1 4 GO:0006898 receptor-mediated endocytosis 6/376 244/18722 0.366230296119365 0.542485625941337 B2M/ITGB2/ITGA4/FCER1G/SORL1/CD81 6 GO:0007179 transforming growth factor beta receptor signaling pathway 5/376 198/18722 0.366470518672001 0.542634031277801 TGFB1/JUN/FOS/ZEB2/STAT3 5 GO:0017156 calcium-ion regulated exocytosis 2/376 64/18722 0.369158821415755 0.545297938944149 VAMP2/RAP1B 2 GO:0030858 positive regulation of epithelial cell differentiation 2/376 64/18722 0.369158821415755 0.545297938944149 BTG1/PRKCH 2 GO:0046530 photoreceptor cell differentiation 2/376 64/18722 0.369158821415755 0.545297938944149 PRDM1/STAT3 2 GO:0080164 regulation of nitric oxide metabolic process 2/376 64/18722 0.369158821415755 0.545297938944149 KLF2/TNF 2 GO:1900076 regulation of cellular response to insulin stimulus 2/376 64/18722 0.369158821415755 0.545297938944149 PIP4K2A/SORL1 2 GO:0071331 cellular response to hexose stimulus 4/376 153/18722 0.36926842304135 0.545297938944149 CYBA/LGALS1/UCP2/XBP1 4 GO:0006958 complement activation, classical pathway 3/376 108/18722 0.369533568127225 0.545297938944149 TRDC/TRBC1/TRBC2 3 GO:0001919 regulation of receptor recycling 1/376 23/18722 0.373054151262178 0.545297938944149 RAB29 1 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1/376 23/18722 0.373054151262178 0.545297938944149 CYBA 1 GO:0006541 glutamine metabolic process 1/376 23/18722 0.373054151262178 0.545297938944149 GLS 1 GO:0009162 deoxyribonucleoside monophosphate metabolic process 1/376 23/18722 0.373054151262178 0.545297938944149 GUK1 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/376 23/18722 0.373054151262178 0.545297938944149 CARD16 1 GO:0031338 regulation of vesicle fusion 1/376 23/18722 0.373054151262178 0.545297938944149 CORO1A 1 GO:0032401 establishment of melanosome localization 1/376 23/18722 0.373054151262178 0.545297938944149 RAB27A 1 GO:0032740 positive regulation of interleukin-17 production 1/376 23/18722 0.373054151262178 0.545297938944149 TGFB1 1 GO:0034105 positive regulation of tissue remodeling 1/376 23/18722 0.373054151262178 0.545297938944149 ROCK1 1 GO:0035812 renal sodium excretion 1/376 23/18722 0.373054151262178 0.545297938944149 MLLT6 1 GO:0036119 response to platelet-derived growth factor 1/376 23/18722 0.373054151262178 0.545297938944149 FYN 1 GO:0040019 positive regulation of embryonic development 1/376 23/18722 0.373054151262178 0.545297938944149 CFL1 1 GO:0042026 protein refolding 1/376 23/18722 0.373054151262178 0.545297938944149 B2M 1 GO:0042438 melanin biosynthetic process 1/376 23/18722 0.373054151262178 0.545297938944149 ZEB2 1 GO:0043931 ossification involved in bone maturation 1/376 23/18722 0.373054151262178 0.545297938944149 SEMA4D 1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 1/376 23/18722 0.373054151262178 0.545297938944149 CHST12 1 GO:0051131 chaperone-mediated protein complex assembly 1/376 23/18722 0.373054151262178 0.545297938944149 HOPX 1 GO:0051383 kinetochore organization 1/376 23/18722 0.373054151262178 0.545297938944149 CENPC 1 GO:0051904 pigment granule transport 1/376 23/18722 0.373054151262178 0.545297938944149 RAB27A 1 GO:0060384 innervation 1/376 23/18722 0.373054151262178 0.545297938944149 ITGA4 1 GO:0060487 lung epithelial cell differentiation 1/376 23/18722 0.373054151262178 0.545297938944149 KLF2 1 GO:0060547 negative regulation of necrotic cell death 1/376 23/18722 0.373054151262178 0.545297938944149 CASP8 1 GO:0060575 intestinal epithelial cell differentiation 1/376 23/18722 0.373054151262178 0.545297938944149 PRDM1 1 GO:0071305 cellular response to vitamin D 1/376 23/18722 0.373054151262178 0.545297938944149 PIM1 1 GO:0071636 positive regulation of transforming growth factor beta production 1/376 23/18722 0.373054151262178 0.545297938944149 XCL1 1 GO:0090335 regulation of brown fat cell differentiation 1/376 23/18722 0.373054151262178 0.545297938944149 PIM1 1 GO:0140112 extracellular vesicle biogenesis 1/376 23/18722 0.373054151262178 0.545297938944149 RAB27A 1 GO:0071326 cellular response to monosaccharide stimulus 4/376 154/18722 0.373827705920492 0.546222609518065 CYBA/LGALS1/UCP2/XBP1 4 GO:0072522 purine-containing compound biosynthetic process 5/376 200/18722 0.374439867153713 0.546910850064318 TMSB4X/TGFB1/STAT3/GUK1/APRT 5 GO:0010965 regulation of mitotic sister chromatid separation 2/376 65/18722 0.376363778253067 0.548893353681081 ATM/DUSP1 2 GO:0043489 RNA stabilization 2/376 65/18722 0.376363778253067 0.548893353681081 ZFP36/PABPC1 2 GO:0044784 metaphase/anaphase transition of cell cycle 2/376 65/18722 0.376363778253067 0.548893353681081 ATM/DUSP1 2 GO:0090307 mitotic spindle assembly 2/376 65/18722 0.376363778253067 0.548893353681081 FLNA/KIF2A 2 GO:0051147 regulation of muscle cell differentiation 4/376 155/18722 0.378384413014449 0.551632656294579 HOPX/TGFB1/ID2/XBP1 4 GO:0007088 regulation of mitotic nuclear division 3/376 110/18722 0.380456237567245 0.553819654610471 ATM/DUSP1/CDC42 3 GO:0014812 muscle cell migration 3/376 110/18722 0.380456237567245 0.553819654610471 CCL5/SORL1/ROCK1 3 GO:0018958 phenol-containing compound metabolic process 3/376 110/18722 0.380456237567245 0.553819654610471 ITGB2/NR4A2/ZEB2 3 GO:1904659 glucose transmembrane transport 3/376 110/18722 0.380456237567245 0.553819654610471 TNF/SLC2A3/PIK3R1 3 GO:0009267 cellular response to starvation 4/376 156/18722 0.382937957100892 0.554252154272548 IFI16/JUN/UCP2/XBP1 4 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 2/376 66/18722 0.38353462455127 0.554252154272548 PTPRC/TGFB1 2 GO:0016444 somatic cell DNA recombination 2/376 66/18722 0.38353462455127 0.554252154272548 PTPRC/TGFB1 2 GO:0050922 negative regulation of chemotaxis 2/376 66/18722 0.38353462455127 0.554252154272548 SEMA4D/DUSP1 2 GO:1905953 negative regulation of lipid localization 2/376 66/18722 0.38353462455127 0.554252154272548 TNF/NFKBIA 2 GO:2000272 negative regulation of signaling receptor activity 2/376 66/18722 0.38353462455127 0.554252154272548 TNF/CBLB 2 GO:0002021 response to dietary excess 1/376 24/18722 0.385660795420979 0.554252154272548 SORL1 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/376 24/18722 0.385660795420979 0.554252154272548 HLA-E 1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1/376 24/18722 0.385660795420979 0.554252154272548 IRF1 1 GO:0006582 melanin metabolic process 1/376 24/18722 0.385660795420979 0.554252154272548 ZEB2 1 GO:0016048 detection of temperature stimulus 1/376 24/18722 0.385660795420979 0.554252154272548 CXCR4 1 GO:0021697 cerebellar cortex formation 1/376 24/18722 0.385660795420979 0.554252154272548 RORA 1 GO:0021801 cerebral cortex radial glia-guided migration 1/376 24/18722 0.385660795420979 0.554252154272548 SUN2 1 GO:0022030 telencephalon glial cell migration 1/376 24/18722 0.385660795420979 0.554252154272548 SUN2 1 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 1/376 24/18722 0.385660795420979 0.554252154272548 KLF2 1 GO:0038095 Fc-epsilon receptor signaling pathway 1/376 24/18722 0.385660795420979 0.554252154272548 FCER1G 1 GO:0044062 regulation of excretion 1/376 24/18722 0.385660795420979 0.554252154272548 SLC9A3R1 1 GO:0044321 response to leptin 1/376 24/18722 0.385660795420979 0.554252154272548 STAT3 1 GO:0048011 neurotrophin TRK receptor signaling pathway 1/376 24/18722 0.385660795420979 0.554252154272548 DDIT4 1 GO:0048641 regulation of skeletal muscle tissue development 1/376 24/18722 0.385660795420979 0.554252154272548 TGFB1 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/376 24/18722 0.385660795420979 0.554252154272548 ATF7IP 1 GO:0051570 regulation of histone H3-K9 methylation 1/376 24/18722 0.385660795420979 0.554252154272548 ATRX 1 GO:0051905 establishment of pigment granule localization 1/376 24/18722 0.385660795420979 0.554252154272548 RAB27A 1 GO:0060479 lung cell differentiation 1/376 24/18722 0.385660795420979 0.554252154272548 KLF2 1 GO:0070841 inclusion body assembly 1/376 24/18722 0.385660795420979 0.554252154272548 SORL1 1 GO:0070935 3'-UTR-mediated mRNA stabilization 1/376 24/18722 0.385660795420979 0.554252154272548 ZFP36 1 GO:0071676 negative regulation of mononuclear cell migration 1/376 24/18722 0.385660795420979 0.554252154272548 DUSP1 1 GO:0090343 positive regulation of cell aging 1/376 24/18722 0.385660795420979 0.554252154272548 B2M 1 GO:1903861 positive regulation of dendrite extension 1/376 24/18722 0.385660795420979 0.554252154272548 CXCR4 1 GO:2000209 regulation of anoikis 1/376 24/18722 0.385660795420979 0.554252154272548 MCL1 1 GO:2000353 positive regulation of endothelial cell apoptotic process 1/376 24/18722 0.385660795420979 0.554252154272548 ITGA4 1 GO:2000679 positive regulation of transcription regulatory region DNA binding 1/376 24/18722 0.385660795420979 0.554252154272548 TGFB1 1 GO:2001026 regulation of endothelial cell chemotaxis 1/376 24/18722 0.385660795420979 0.554252154272548 TMSB4X 1 GO:0001938 positive regulation of endothelial cell proliferation 3/376 111/18722 0.385902532187699 0.554252154272548 CYBA/ITGA4/STAT3 3 GO:0071867 response to monoamine 3/376 111/18722 0.385902532187699 0.554252154272548 GNG2/FLNA/SLC9A3R1 3 GO:0071869 response to catecholamine 3/376 111/18722 0.385902532187699 0.554252154272548 GNG2/FLNA/SLC9A3R1 3 GO:0060541 respiratory system development 5/376 203/18722 0.386391955977728 0.554749473661985 KLF2/HOPX/TNF/YWHAZ/CDC42 5 GO:0000280 nuclear division 10/376 439/18722 0.387861060453821 0.556446356630343 MYBL1/ATM/FLNA/DUSP1/KIF2A/ACTR3/CDC42/ACTR2/ATRX/CENPC 10 GO:0050804 modulation of chemical synaptic transmission 10/376 439/18722 0.387861060453821 0.556446356630343 FYN/SRGN/TNF/CALM1/TYROBP/DGKZ/VAMP2/RAP1B/RNF19A/STAT3 10 GO:0099177 regulation of trans-synaptic signaling 10/376 440/18722 0.390560541096758 0.559233679713629 FYN/SRGN/TNF/CALM1/TYROBP/DGKZ/VAMP2/RAP1B/RNF19A/STAT3 10 GO:0010517 regulation of phospholipase activity 2/376 67/18722 0.390669824770269 0.559233679713629 CCL5/TXK 2 GO:0043967 histone H4 acetylation 2/376 67/18722 0.390669824770269 0.559233679713629 KMT2A/EPC1 2 GO:0048814 regulation of dendrite morphogenesis 2/376 67/18722 0.390669824770269 0.559233679713629 SEMA4D/ACTR2 2 GO:0051306 mitotic sister chromatid separation 2/376 67/18722 0.390669824770269 0.559233679713629 ATM/DUSP1 2 GO:0061180 mammary gland epithelium development 2/376 67/18722 0.390669824770269 0.559233679713629 LBH/ID2 2 GO:0048511 rhythmic process 7/376 298/18722 0.391180903575238 0.559569449126422 ETS1/RORA/DDX5/JUN/ID2/JUND/KMT2A 7 GO:0035601 protein deacylation 3/376 112/18722 0.391337601840672 0.559569449126422 HOPX/FLNA/ABHD17A 3 GO:0048640 negative regulation of developmental growth 3/376 112/18722 0.391337601840672 0.559569449126422 PLAC8/STK4/SEMA4D 3 GO:0032200 telomere organization 4/376 159/18722 0.396573871008417 0.562065086124562 ATM/SP100/TERF2IP/ATRX 4 GO:0046488 phosphatidylinositol metabolic process 4/376 159/18722 0.396573871008417 0.562065086124562 PLEK/PIP4K2A/ATM/PIK3R1 4 GO:0031623 receptor internalization 3/376 113/18722 0.396760575271018 0.562065086124562 ITGB2/FCER1G/CD81 3 GO:0010812 negative regulation of cell-substrate adhesion 2/376 68/18722 0.397767918447841 0.562065086124562 LGALS1/PIK3R1 2 GO:0046637 regulation of alpha-beta T cell differentiation 2/376 68/18722 0.397767918447841 0.562065086124562 RUNX3/PRDM1 2 GO:0051148 negative regulation of muscle cell differentiation 2/376 68/18722 0.397767918447841 0.562065086124562 ID2/XBP1 2 GO:0061912 selective autophagy 2/376 68/18722 0.397767918447841 0.562065086124562 TOMM7/VPS13C 2 GO:1902305 regulation of sodium ion transmembrane transport 2/376 68/18722 0.397767918447841 0.562065086124562 FXYD5/SLC9A3R1 2 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 1/376 25/18722 0.398014605503432 0.562065086124562 CYBA 1 GO:0003094 glomerular filtration 1/376 25/18722 0.398014605503432 0.562065086124562 CYBA 1 GO:0010447 response to acidic pH 1/376 25/18722 0.398014605503432 0.562065086124562 GPR65 1 GO:0015874 norepinephrine transport 1/376 25/18722 0.398014605503432 0.562065086124562 ACTB 1 GO:0032400 melanosome localization 1/376 25/18722 0.398014605503432 0.562065086124562 RAB27A 1 GO:0033119 negative regulation of RNA splicing 1/376 25/18722 0.398014605503432 0.562065086124562 SRSF7 1 GO:0036315 cellular response to sterol 1/376 25/18722 0.398014605503432 0.562065086124562 RORA 1 GO:0044550 secondary metabolite biosynthetic process 1/376 25/18722 0.398014605503432 0.562065086124562 ZEB2 1 GO:0045109 intermediate filament organization 1/376 25/18722 0.398014605503432 0.562065086124562 VIM 1 GO:0045324 late endosome to vacuole transport 1/376 25/18722 0.398014605503432 0.562065086124562 LEPROTL1 1 GO:0046039 GTP metabolic process 1/376 25/18722 0.398014605503432 0.562065086124562 GIMAP7 1 GO:0046339 diacylglycerol metabolic process 1/376 25/18722 0.398014605503432 0.562065086124562 DGKZ 1 GO:0046835 carbohydrate phosphorylation 1/376 25/18722 0.398014605503432 0.562065086124562 GNPTAB 1 GO:0048143 astrocyte activation 1/376 25/18722 0.398014605503432 0.562065086124562 TNF 1 GO:0050951 sensory perception of temperature stimulus 1/376 25/18722 0.398014605503432 0.562065086124562 CXCR4 1 GO:0051204 protein insertion into mitochondrial membrane 1/376 25/18722 0.398014605503432 0.562065086124562 GZMB 1 GO:0051450 myoblast proliferation 1/376 25/18722 0.398014605503432 0.562065086124562 MALAT1 1 GO:0072012 glomerulus vasculature development 1/376 25/18722 0.398014605503432 0.562065086124562 CFLAR 1 GO:0072202 cell differentiation involved in metanephros development 1/376 25/18722 0.398014605503432 0.562065086124562 STAT1 1 GO:0072207 metanephric epithelium development 1/376 25/18722 0.398014605503432 0.562065086124562 STAT1 1 GO:0086013 membrane repolarization during cardiac muscle cell action potential 1/376 25/18722 0.398014605503432 0.562065086124562 FLNA 1 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 1/376 25/18722 0.398014605503432 0.562065086124562 CALM1 1 GO:0090382 phagosome maturation 1/376 25/18722 0.398014605503432 0.562065086124562 CORO1A 1 GO:0098703 calcium ion import across plasma membrane 1/376 25/18722 0.398014605503432 0.562065086124562 FYN 1 GO:1900078 positive regulation of cellular response to insulin stimulus 1/376 25/18722 0.398014605503432 0.562065086124562 SORL1 1 GO:1902993 positive regulation of amyloid precursor protein catabolic process 1/376 25/18722 0.398014605503432 0.562065086124562 TNF 1 GO:0006163 purine nucleotide metabolic process 9/376 396/18722 0.400713378225948 0.565670069444645 TMSB4X/GIMAP7/RORA/DDIT4/TGFB1/SAMHD1/STAT3/GUK1/APRT 9 GO:0042886 amide transport 7/376 301/18722 0.40103576806669 0.565919009926593 CCL5/TNF/TAP1/RAB8B/UCP2/SLC9A3R1/TAPBP 7 GO:0016055 Wnt signaling pathway 10/376 444/18722 0.401369145586567 0.566183268710574 RNF213/STK4/TGFB1/TNFAIP3/NR4A2/CYLD/ZEB2/SLC9A3R1/CDC42/MACF1 10 GO:0008645 hexose transmembrane transport 3/376 114/18722 0.402170602973765 0.566901086403542 TNF/SLC2A3/PIK3R1 3 GO:0051261 protein depolymerization 3/376 114/18722 0.402170602973765 0.566901086403542 PLEK/CFL1/KIF2A 3 GO:0007004 telomere maintenance via telomerase 2/376 69/18722 0.404827517817484 0.569610251104848 ATM/TERF2IP 2 GO:0045665 negative regulation of neuron differentiation 2/376 69/18722 0.404827517817484 0.569610251104848 B2M/DDX6 2 GO:0050810 regulation of steroid biosynthetic process 2/376 69/18722 0.404827517817484 0.569610251104848 TNF/SF1 2 GO:0051966 regulation of synaptic transmission, glutamatergic 2/376 69/18722 0.404827517817484 0.569610251104848 TNF/DGKZ 2 GO:0060193 positive regulation of lipase activity 2/376 69/18722 0.404827517817484 0.569610251104848 CCL5/TXK 2 GO:0051650 establishment of vesicle localization 4/376 161/18722 0.405638296568804 0.570543883558662 RASGRP1/ITGA4/RAB27A/MYO1F 4 GO:0198738 cell-cell signaling by wnt 10/376 446/18722 0.406778041964269 0.571100960905793 RNF213/STK4/TGFB1/TNFAIP3/NR4A2/CYLD/ZEB2/SLC9A3R1/CDC42/MACF1 10 GO:0090630 activation of GTPase activity 3/376 115/18722 0.407566857027413 0.571100960905793 GPR65/RASGRP1/TBC1D10C 3 GO:0010875 positive regulation of cholesterol efflux 1/376 26/18722 0.410120639002427 0.571100960905793 NFKBIA 1 GO:0018027 peptidyl-lysine dimethylation 1/376 26/18722 0.410120639002427 0.571100960905793 KMT2A 1 GO:0021680 cerebellar Purkinje cell layer development 1/376 26/18722 0.410120639002427 0.571100960905793 RORA 1 GO:0021952 central nervous system projection neuron axonogenesis 1/376 26/18722 0.410120639002427 0.571100960905793 NR4A2 1 GO:0033598 mammary gland epithelial cell proliferation 1/376 26/18722 0.410120639002427 0.571100960905793 ID2 1 GO:0034063 stress granule assembly 1/376 26/18722 0.410120639002427 0.571100960905793 DDX6 1 GO:0042278 purine nucleoside metabolic process 1/376 26/18722 0.410120639002427 0.571100960905793 APRT 1 GO:0042634 regulation of hair cycle 1/376 26/18722 0.410120639002427 0.571100960905793 TNF 1 GO:0043094 cellular metabolic compound salvage 1/376 26/18722 0.410120639002427 0.571100960905793 APRT 1 GO:0043501 skeletal muscle adaptation 1/376 26/18722 0.410120639002427 0.571100960905793 CFLAR 1 GO:0046639 negative regulation of alpha-beta T cell differentiation 1/376 26/18722 0.410120639002427 0.571100960905793 RUNX3 1 GO:0046697 decidualization 1/376 26/18722 0.410120639002427 0.571100960905793 JUNB 1 GO:0048668 collateral sprouting 1/376 26/18722 0.410120639002427 0.571100960905793 SEMA4D 1 GO:0048843 negative regulation of axon extension involved in axon guidance 1/376 26/18722 0.410120639002427 0.571100960905793 SEMA4D 1 GO:0051875 pigment granule localization 1/376 26/18722 0.410120639002427 0.571100960905793 RAB27A 1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 1/376 26/18722 0.410120639002427 0.571100960905793 CALM1 1 GO:0070977 bone maturation 1/376 26/18722 0.410120639002427 0.571100960905793 SEMA4D 1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 1/376 26/18722 0.410120639002427 0.571100960905793 AKAP13 1 GO:0072273 metanephric nephron morphogenesis 1/376 26/18722 0.410120639002427 0.571100960905793 STAT1 1 GO:0097205 renal filtration 1/376 26/18722 0.410120639002427 0.571100960905793 CYBA 1 GO:0099637 neurotransmitter receptor transport 1/376 26/18722 0.410120639002427 0.571100960905793 VAMP2 1 GO:1902656 calcium ion import into cytosol 1/376 26/18722 0.410120639002427 0.571100960905793 FYN 1 GO:1904353 regulation of telomere capping 1/376 26/18722 0.410120639002427 0.571100960905793 ATM 1 GO:2000050 regulation of non-canonical Wnt signaling pathway 1/376 26/18722 0.410120639002427 0.571100960905793 RNF213 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/376 26/18722 0.410120639002427 0.571100960905793 CCL5 1 GO:0021953 central nervous system neuron differentiation 4/376 162/18722 0.410161025600212 0.571100960905793 B2M/RORA/NR4A2/BTG2 4 GO:0007006 mitochondrial membrane organization 3/376 116/18722 0.412948530918167 0.573951060727366 GZMB/CALM1/STAT3 3 GO:0008286 insulin receptor signaling pathway 3/376 116/18722 0.412948530918167 0.573951060727366 PIP4K2A/PIK3R1/SORL1 3 GO:0015749 monosaccharide transmembrane transport 3/376 116/18722 0.412948530918167 0.573951060727366 TNF/SLC2A3/PIK3R1 3 GO:0035967 cellular response to topologically incorrect protein 3/376 116/18722 0.412948530918167 0.573951060727366 PIK3R1/XBP1/PPP1R15A 3 GO:0098732 macromolecule deacylation 3/376 116/18722 0.412948530918167 0.573951060727366 HOPX/FLNA/ABHD17A 3 GO:0007623 circadian rhythm 5/376 210/18722 0.414215242081965 0.57550522160904 RORA/JUN/ID2/JUND/KMT2A 5 GO:0010976 positive regulation of neuron projection development 4/376 163/18722 0.414676729247389 0.575733545622943 FYN/FLNA/ACTR2/CFLAR 4 GO:0071322 cellular response to carbohydrate stimulus 4/376 163/18722 0.414676729247389 0.575733545622943 CYBA/LGALS1/UCP2/XBP1 4 GO:0042593 glucose homeostasis 6/376 258/18722 0.41636577118311 0.577871548472261 CYBA/LGALS1/UCP2/PIK3R1/XBP1/STAT3 6 GO:0000281 mitotic cytokinesis 2/376 71/18722 0.418826032205943 0.579442745739097 SON/ROCK1 2 GO:0008344 adult locomotory behavior 2/376 71/18722 0.418826032205943 0.579442745739097 CCND2/NR4A2 2 GO:0050795 regulation of behavior 2/376 71/18722 0.418826032205943 0.579442745739097 CCL3/STAT3 2 GO:0033500 carbohydrate homeostasis 6/376 259/18722 0.41993812330922 0.579442745739097 CYBA/LGALS1/UCP2/PIK3R1/XBP1/STAT3 6 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 8/376 355/18722 0.420931944527264 0.579442745739097 VIM/DDX5/TGFB1/JUN/FOS/ZEB2/SORL1/STAT3 8 GO:0001835 blastocyst hatching 1/376 27/18722 0.421983852509867 0.579442745739097 CMTM3 1 GO:0002227 innate immune response in mucosa 1/376 27/18722 0.421983852509867 0.579442745739097 RPL39 1 GO:0002825 regulation of T-helper 1 type immune response 1/376 27/18722 0.421983852509867 0.579442745739097 XCL1 1 GO:0009651 response to salt stress 1/376 27/18722 0.421983852509867 0.579442745739097 TNF 1 GO:0010561 negative regulation of glycoprotein biosynthetic process 1/376 27/18722 0.421983852509867 0.579442745739097 ITM2A 1 GO:0010586 miRNA metabolic process 1/376 27/18722 0.421983852509867 0.579442745739097 DDX17 1 GO:0010758 regulation of macrophage chemotaxis 1/376 27/18722 0.421983852509867 0.579442745739097 CCL5 1 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 1/376 27/18722 0.421983852509867 0.579442745739097 CALM1 1 GO:0018195 peptidyl-arginine modification 1/376 27/18722 0.421983852509867 0.579442745739097 PRMT2 1 GO:0031954 positive regulation of protein autophosphorylation 1/376 27/18722 0.421983852509867 0.579442745739097 CALM1 1 GO:0032781 positive regulation of ATPase activity 1/376 27/18722 0.421983852509867 0.579442745739097 PFN1 1 GO:0034377 plasma lipoprotein particle assembly 1/376 27/18722 0.421983852509867 0.579442745739097 PRKACB 1 GO:0034453 microtubule anchoring 1/376 27/18722 0.421983852509867 0.579442745739097 GCC2 1 GO:0035188 hatching 1/376 27/18722 0.421983852509867 0.579442745739097 CMTM3 1 GO:0042104 positive regulation of activated T cell proliferation 1/376 27/18722 0.421983852509867 0.579442745739097 PYCARD 1 GO:0045606 positive regulation of epidermal cell differentiation 1/376 27/18722 0.421983852509867 0.579442745739097 PRKCH 1 GO:0048873 homeostasis of number of cells within a tissue 1/376 27/18722 0.421983852509867 0.579442745739097 CORO1A 1 GO:0060512 prostate gland morphogenesis 1/376 27/18722 0.421983852509867 0.579442745739097 CRIP1 1 GO:0061437 renal system vasculature development 1/376 27/18722 0.421983852509867 0.579442745739097 CFLAR 1 GO:0061440 kidney vasculature development 1/376 27/18722 0.421983852509867 0.579442745739097 CFLAR 1 GO:0071684 organism emergence from protective structure 1/376 27/18722 0.421983852509867 0.579442745739097 CMTM3 1 GO:0098901 regulation of cardiac muscle cell action potential 1/376 27/18722 0.421983852509867 0.579442745739097 CALM1 1 GO:1902914 regulation of protein polyubiquitination 1/376 27/18722 0.421983852509867 0.579442745739097 PTPN22 1 GO:1903203 regulation of oxidative stress-induced neuron death 1/376 27/18722 0.421983852509867 0.579442745739097 MCL1 1 GO:1903859 regulation of dendrite extension 1/376 27/18722 0.421983852509867 0.579442745739097 CXCR4 1 GO:0034219 carbohydrate transmembrane transport 3/376 118/18722 0.423665018080665 0.581545145257732 TNF/SLC2A3/PIK3R1 3 GO:0033045 regulation of sister chromatid segregation 2/376 72/18722 0.425762514630991 0.583803872680499 ATM/DUSP1 2 GO:0035567 non-canonical Wnt signaling pathway 2/376 72/18722 0.425762514630991 0.583803872680499 RNF213/CDC42 2 GO:1905818 regulation of chromosome separation 2/376 72/18722 0.425762514630991 0.583803872680499 ATM/DUSP1 2 GO:0051047 positive regulation of secretion 7/376 310/18722 0.430558723782626 0.588729949871118 HLA-F/CYBA/ITGB2/TGFB1/RAB27A/RAB8B/XBP1 7 GO:0032456 endocytic recycling 2/376 73/18722 0.432655633236596 0.588729949871118 ARL4C/SORL1 2 GO:0045739 positive regulation of DNA repair 2/376 73/18722 0.432655633236596 0.588729949871118 WAS/ACTR2 2 GO:0070988 demethylation 2/376 73/18722 0.432655633236596 0.588729949871118 APOBEC3G/APOBEC3C 2 GO:0099518 vesicle cytoskeletal trafficking 2/376 73/18722 0.432655633236596 0.588729949871118 RASGRP1/MYO1F 2 GO:1904427 positive regulation of calcium ion transmembrane transport 2/376 73/18722 0.432655633236596 0.588729949871118 XCL1/CALM1 2 GO:0009306 protein secretion 8/376 359/18722 0.433117264646595 0.588729949871118 CCL5/PLEK/TNF/TGFB1/RAB8B/UCP2/GNPTAB/DNAJC1 8 GO:0000303 response to superoxide 1/376 28/18722 0.433609103724431 0.588729949871118 UCP2 1 GO:0006972 hyperosmotic response 1/376 28/18722 0.433609103724431 0.588729949871118 RCSD1 1 GO:0007064 mitotic sister chromatid cohesion 1/376 28/18722 0.433609103724431 0.588729949871118 ATRX 1 GO:0007141 male meiosis I 1/376 28/18722 0.433609103724431 0.588729949871118 MYBL1 1 GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1/376 28/18722 0.433609103724431 0.588729949871118 DGKZ 1 GO:0009065 glutamine family amino acid catabolic process 1/376 28/18722 0.433609103724431 0.588729949871118 GLS 1 GO:0010464 regulation of mesenchymal cell proliferation 1/376 28/18722 0.433609103724431 0.588729949871118 STAT1 1 GO:0032607 interferon-alpha production 1/376 28/18722 0.433609103724431 0.588729949871118 STAT1 1 GO:0032647 regulation of interferon-alpha production 1/376 28/18722 0.433609103724431 0.588729949871118 STAT1 1 GO:0032958 inositol phosphate biosynthetic process 1/376 28/18722 0.433609103724431 0.588729949871118 PLEK 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/376 28/18722 0.433609103724431 0.588729949871118 CBLB 1 GO:0042983 amyloid precursor protein biosynthetic process 1/376 28/18722 0.433609103724431 0.588729949871118 ITM2A 1 GO:0042984 regulation of amyloid precursor protein biosynthetic process 1/376 28/18722 0.433609103724431 0.588729949871118 ITM2A 1 GO:0045589 regulation of regulatory T cell differentiation 1/376 28/18722 0.433609103724431 0.588729949871118 IRF1 1 GO:0051894 positive regulation of focal adhesion assembly 1/376 28/18722 0.433609103724431 0.588729949871118 ROCK1 1 GO:0060259 regulation of feeding behavior 1/376 28/18722 0.433609103724431 0.588729949871118 STAT3 1 GO:0086011 membrane repolarization during action potential 1/376 28/18722 0.433609103724431 0.588729949871118 FLNA 1 GO:0090200 positive regulation of release of cytochrome c from mitochondria 1/376 28/18722 0.433609103724431 0.588729949871118 PYCARD 1 GO:0099623 regulation of cardiac muscle cell membrane repolarization 1/376 28/18722 0.433609103724431 0.588729949871118 FLNA 1 GO:1903671 negative regulation of sprouting angiogenesis 1/376 28/18722 0.433609103724431 0.588729949871118 KLF2 1 GO:1903672 positive regulation of sprouting angiogenesis 1/376 28/18722 0.433609103724431 0.588729949871118 JAK1 1 GO:0031669 cellular response to nutrient levels 5/376 215/18722 0.433976307426709 0.589022133547634 IFI16/JUN/UCP2/XBP1/PIM1 5 GO:0007052 mitotic spindle organization 3/376 120/18722 0.434314033307288 0.589067861066062 FLNA/SUN2/KIF2A 3 GO:0032411 positive regulation of transporter activity 3/376 120/18722 0.434314033307288 0.589067861066062 TMSB4X/CALM1/KMT2A 3 GO:0035592 establishment of protein localization to extracellular region 8/376 360/18722 0.436159820759216 0.591364347600406 CCL5/PLEK/TNF/TGFB1/RAB8B/UCP2/GNPTAB/DNAJC1 8 GO:0000070 mitotic sister chromatid segregation 4/376 168/18722 0.437132126734099 0.592268178704418 ATM/DUSP1/ATRX/CENPC 4 GO:2000241 regulation of reproductive process 4/376 168/18722 0.437132126734099 0.592268178704418 ARHGDIB/STK4/PRKACB/DUSP1 4 GO:0010822 positive regulation of mitochondrion organization 2/376 74/18722 0.439504330220477 0.594587905020286 GZMB/PYCARD 2 GO:0051881 regulation of mitochondrial membrane potential 2/376 74/18722 0.439504330220477 0.594587905020286 UCP2/CLIC1 2 GO:1903201 regulation of oxidative stress-induced cell death 2/376 74/18722 0.439504330220477 0.594587905020286 FYN/MCL1 2 GO:0042177 negative regulation of protein catabolic process 3/376 121/18722 0.439611444614998 0.594587905020286 FYN/FLNA/ROCK1 3 GO:0043500 muscle adaptation 3/376 121/18722 0.439611444614998 0.594587905020286 CYBA/CFLAR/ROCK1 3 GO:0000305 response to oxygen radical 1/376 29/18722 0.4450011534195 0.598742871354362 UCP2 1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1/376 29/18722 0.4450011534195 0.598742871354362 FYN 1 GO:0019082 viral protein processing 1/376 29/18722 0.4450011534195 0.598742871354362 MGAT4A 1 GO:0019433 triglyceride catabolic process 1/376 29/18722 0.4450011534195 0.598742871354362 SORL1 1 GO:0021772 olfactory bulb development 1/376 29/18722 0.4450011534195 0.598742871354362 ID2 1 GO:0032366 intracellular sterol transport 1/376 29/18722 0.4450011534195 0.598742871354362 PIP4K2A 1 GO:0032367 intracellular cholesterol transport 1/376 29/18722 0.4450011534195 0.598742871354362 PIP4K2A 1 GO:0043153 entrainment of circadian clock by photoperiod 1/376 29/18722 0.4450011534195 0.598742871354362 ID2 1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 1/376 29/18722 0.4450011534195 0.598742871354362 CCND2 1 GO:0048679 regulation of axon regeneration 1/376 29/18722 0.4450011534195 0.598742871354362 FLNA 1 GO:0050686 negative regulation of mRNA processing 1/376 29/18722 0.4450011534195 0.598742871354362 SRSF7 1 GO:0060441 epithelial tube branching involved in lung morphogenesis 1/376 29/18722 0.4450011534195 0.598742871354362 TNF 1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1/376 29/18722 0.4450011534195 0.598742871354362 MCL1 1 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1/376 29/18722 0.4450011534195 0.598742871354362 CD44 1 GO:1903902 positive regulation of viral life cycle 1/376 29/18722 0.4450011534195 0.598742871354362 LGALS1 1 GO:0030178 negative regulation of Wnt signaling pathway 4/376 170/18722 0.446047747820257 0.599252244986404 RNF213/STK4/CYLD/SLC9A3R1 4 GO:0006024 glycosaminoglycan biosynthetic process 2/376 75/18722 0.44630760749181 0.599252244986404 TGFB1/CHST12 2 GO:0006278 RNA-dependent DNA biosynthetic process 2/376 75/18722 0.44630760749181 0.599252244986404 ATM/TERF2IP 2 GO:0048662 negative regulation of smooth muscle cell proliferation 2/376 75/18722 0.44630760749181 0.599252244986404 TNFAIP3/SF1 2 GO:1902369 negative regulation of RNA catabolic process 2/376 75/18722 0.44630760749181 0.599252244986404 ZFP36/PABPC1 2 GO:2001259 positive regulation of cation channel activity 2/376 75/18722 0.44630760749181 0.599252244986404 TMSB4X/CALM1 2 GO:0071482 cellular response to light stimulus 3/376 123/18722 0.450148663403081 0.60420023231276 CRIP1/PIK3R1/CARD16 3 GO:0001937 negative regulation of endothelial cell proliferation 2/376 76/18722 0.45306452471089 0.606601951292567 TNF/STAT1 2 GO:0009123 nucleoside monophosphate metabolic process 2/376 76/18722 0.45306452471089 0.606601951292567 GUK1/APRT 2 GO:0014823 response to activity 2/376 76/18722 0.45306452471089 0.606601951292567 CYBA/CXCR4 2 GO:0021536 diencephalon development 2/376 76/18722 0.45306452471089 0.606601951292567 ETS1/NR4A2 2 GO:0086001 cardiac muscle cell action potential 2/376 76/18722 0.45306452471089 0.606601951292567 CALM1/FLNA 2 GO:0140029 exocytic process 2/376 76/18722 0.45306452471089 0.606601951292567 PLEK/RAB8B 2 GO:1990138 neuron projection extension 4/376 172/18722 0.45491978021376 0.606601951292567 CXCR4/ITGA4/SEMA4D/MACF1 4 GO:0009132 nucleoside diphosphate metabolic process 3/376 124/18722 0.455387166161577 0.606601951292567 DDIT4/STAT3/GUK1 3 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/376 30/18722 0.45616466737201 0.606601951292567 CBLB 1 GO:0007202 activation of phospholipase C activity 1/376 30/18722 0.45616466737201 0.606601951292567 TXK 1 GO:0009264 deoxyribonucleotide catabolic process 1/376 30/18722 0.45616466737201 0.606601951292567 SAMHD1 1 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1/376 30/18722 0.45616466737201 0.606601951292567 CALM1 1 GO:0030204 chondroitin sulfate metabolic process 1/376 30/18722 0.45616466737201 0.606601951292567 CHST12 1 GO:0031571 mitotic G1 DNA damage checkpoint signaling 1/376 30/18722 0.45616466737201 0.606601951292567 ATM 1 GO:0033137 negative regulation of peptidyl-serine phosphorylation 1/376 30/18722 0.45616466737201 0.606601951292567 DDIT4 1 GO:0034390 smooth muscle cell apoptotic process 1/376 30/18722 0.45616466737201 0.606601951292567 STK4 1 GO:0034391 regulation of smooth muscle cell apoptotic process 1/376 30/18722 0.45616466737201 0.606601951292567 STK4 1 GO:0034508 centromere complex assembly 1/376 30/18722 0.45616466737201 0.606601951292567 CENPC 1 GO:0043304 regulation of mast cell degranulation 1/376 30/18722 0.45616466737201 0.606601951292567 RAC2 1 GO:0044788 modulation by host of viral process 1/376 30/18722 0.45616466737201 0.606601951292567 CFL1 1 GO:0045940 positive regulation of steroid metabolic process 1/376 30/18722 0.45616466737201 0.606601951292567 TNF 1 GO:0046825 regulation of protein export from nucleus 1/376 30/18722 0.45616466737201 0.606601951292567 SP100 1 GO:0048799 animal organ maturation 1/376 30/18722 0.45616466737201 0.606601951292567 SEMA4D 1 GO:0060218 hematopoietic stem cell differentiation 1/376 30/18722 0.45616466737201 0.606601951292567 N4BP2L2 1 GO:0060674 placenta blood vessel development 1/376 30/18722 0.45616466737201 0.606601951292567 JUNB 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/376 30/18722 0.45616466737201 0.606601951292567 TGFB1 1 GO:1903019 negative regulation of glycoprotein metabolic process 1/376 30/18722 0.45616466737201 0.606601951292567 ITM2A 1 GO:0072521 purine-containing compound metabolic process 9/376 416/18722 0.457852112864028 0.60863702824978 TMSB4X/GIMAP7/RORA/DDIT4/TGFB1/SAMHD1/STAT3/GUK1/APRT 9 GO:0010827 regulation of glucose transmembrane transport 2/376 77/18722 0.459774197383102 0.610773059602167 TNF/PIK3R1 2 GO:1901983 regulation of protein acetylation 2/376 77/18722 0.459774197383102 0.610773059602167 KMT2A/TERF2IP 2 GO:0009150 purine ribonucleotide metabolic process 8/376 368/18722 0.46041953986665 0.611211276801394 TMSB4X/GIMAP7/RORA/DDIT4/TGFB1/STAT3/GUK1/APRT 8 GO:0071692 protein localization to extracellular region 8/376 368/18722 0.46041953986665 0.611211276801394 CCL5/PLEK/TNF/TGFB1/RAB8B/UCP2/GNPTAB/DNAJC1 8 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 2/376 78/18722 0.466435795005815 0.615237541036884 RGS1/FLNA 2 GO:0043537 negative regulation of blood vessel endothelial cell migration 2/376 78/18722 0.466435795005815 0.615237541036884 TNF/TGFB1 2 GO:0001782 B cell homeostasis 1/376 31/18722 0.467104218253035 0.615237541036884 TNFAIP3 1 GO:0007190 activation of adenylate cyclase activity 1/376 31/18722 0.467104218253035 0.615237541036884 CALM1 1 GO:0008045 motor neuron axon guidance 1/376 31/18722 0.467104218253035 0.615237541036884 RAC2 1 GO:0021988 olfactory lobe development 1/376 31/18722 0.467104218253035 0.615237541036884 ID2 1 GO:0033006 regulation of mast cell activation involved in immune response 1/376 31/18722 0.467104218253035 0.615237541036884 RAC2 1 GO:0036257 multivesicular body organization 1/376 31/18722 0.467104218253035 0.615237541036884 RAB27A 1 GO:0036475 neuron death in response to oxidative stress 1/376 31/18722 0.467104218253035 0.615237541036884 MCL1 1 GO:0043171 peptide catabolic process 1/376 31/18722 0.467104218253035 0.615237541036884 LNPEP 1 GO:0044819 mitotic G1/S transition checkpoint signaling 1/376 31/18722 0.467104218253035 0.615237541036884 ATM 1 GO:0045066 regulatory T cell differentiation 1/376 31/18722 0.467104218253035 0.615237541036884 IRF1 1 GO:0046386 deoxyribose phosphate catabolic process 1/376 31/18722 0.467104218253035 0.615237541036884 SAMHD1 1 GO:0048384 retinoic acid receptor signaling pathway 1/376 31/18722 0.467104218253035 0.615237541036884 KLF2 1 GO:0048710 regulation of astrocyte differentiation 1/376 31/18722 0.467104218253035 0.615237541036884 ID2 1 GO:0060045 positive regulation of cardiac muscle cell proliferation 1/376 31/18722 0.467104218253035 0.615237541036884 PIM1 1 GO:0060390 regulation of SMAD protein signal transduction 1/376 31/18722 0.467104218253035 0.615237541036884 TGFB1 1 GO:0060795 cell fate commitment involved in formation of primary germ layer 1/376 31/18722 0.467104218253035 0.615237541036884 EOMES 1 GO:0065005 protein-lipid complex assembly 1/376 31/18722 0.467104218253035 0.615237541036884 PRKACB 1 GO:0070528 protein kinase C signaling 1/376 31/18722 0.467104218253035 0.615237541036884 PLEK 1 GO:0090183 regulation of kidney development 1/376 31/18722 0.467104218253035 0.615237541036884 STAT1 1 GO:1901797 negative regulation of signal transduction by p53 class mediator 1/376 31/18722 0.467104218253035 0.615237541036884 CD44 1 GO:2000144 positive regulation of DNA-templated transcription, initiation 1/376 31/18722 0.467104218253035 0.615237541036884 JUN 1 GO:0048565 digestive tract development 3/376 127/18722 0.470974829118953 0.619914219713296 PRDM1/TNF/ID2 3 GO:0051224 negative regulation of protein transport 3/376 127/18722 0.470974829118953 0.619914219713296 SP100/UCP2/CSK 3 GO:0043534 blood vessel endothelial cell migration 4/376 176/18722 0.472519169666089 0.621735749560643 TMSB4X/ETS1/TNF/TGFB1 4 GO:0006364 rRNA processing 5/376 225/18722 0.473023420421672 0.62179887708924 ISG20/RPS27/RPL35A/LYAR/DDX17 5 GO:0006023 aminoglycan biosynthetic process 2/376 79/18722 0.473048539266859 0.62179887708924 TGFB1/CHST12 2 GO:0050772 positive regulation of axonogenesis 2/376 79/18722 0.473048539266859 0.62179887708924 SEMA4D/MACF1 2 GO:0051648 vesicle localization 4/376 177/18722 0.476886458113633 0.623004412512869 RASGRP1/ITGA4/RAB27A/MYO1F 4 GO:0003338 metanephros morphogenesis 1/376 32/18722 0.477824287480838 0.623004412512869 STAT1 1 GO:0006308 DNA catabolic process 1/376 32/18722 0.477824287480838 0.623004412512869 ISG20 1 GO:0010039 response to iron ion 1/376 32/18722 0.477824287480838 0.623004412512869 B2M 1 GO:0010644 cell communication by electrical coupling 1/376 32/18722 0.477824287480838 0.623004412512869 CALM1 1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process 1/376 32/18722 0.477824287480838 0.623004412512869 CFLAR 1 GO:0021799 cerebral cortex radially oriented cell migration 1/376 32/18722 0.477824287480838 0.623004412512869 SUN2 1 GO:0030431 sleep 1/376 32/18722 0.477824287480838 0.623004412512869 FOS 1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1/376 32/18722 0.477824287480838 0.623004412512869 ZEB2 1 GO:0033687 osteoblast proliferation 1/376 32/18722 0.477824287480838 0.623004412512869 JUNB 1 GO:0035767 endothelial cell chemotaxis 1/376 32/18722 0.477824287480838 0.623004412512869 TMSB4X 1 GO:0045684 positive regulation of epidermis development 1/376 32/18722 0.477824287480838 0.623004412512869 PRKCH 1 GO:0048841 regulation of axon extension involved in axon guidance 1/376 32/18722 0.477824287480838 0.623004412512869 SEMA4D 1 GO:0050685 positive regulation of mRNA processing 1/376 32/18722 0.477824287480838 0.623004412512869 NCL 1 GO:0051642 centrosome localization 1/376 32/18722 0.477824287480838 0.623004412512869 SUN2 1 GO:0060914 heart formation 1/376 32/18722 0.477824287480838 0.623004412512869 PIM1 1 GO:0071875 adrenergic receptor signaling pathway 1/376 32/18722 0.477824287480838 0.623004412512869 AKAP13 1 GO:0072337 modified amino acid transport 1/376 32/18722 0.477824287480838 0.623004412512869 SLC9A3R1 1 GO:0097345 mitochondrial outer membrane permeabilization 1/376 32/18722 0.477824287480838 0.623004412512869 GZMB 1 GO:1900745 positive regulation of p38MAPK cascade 1/376 32/18722 0.477824287480838 0.623004412512869 GADD45B 1 GO:1901185 negative regulation of ERBB signaling pathway 1/376 32/18722 0.477824287480838 0.623004412512869 CBLB 1 GO:1901532 regulation of hematopoietic progenitor cell differentiation 1/376 32/18722 0.477824287480838 0.623004412512869 N4BP2L2 1 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/376 32/18722 0.477824287480838 0.623004412512869 XBP1 1 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 1/376 32/18722 0.477824287480838 0.623004412512869 ZEB2 1 GO:0001570 vasculogenesis 2/376 80/18722 0.479611702293262 0.625124569924786 TGFB1/JUNB 2 GO:0098657 import into cell 5/376 227/18722 0.480734910068137 0.62637786701884 FYN/ITGA4/ACTB/IL10RA/SLC2A3 5 GO:0007093 mitotic cell cycle checkpoint signaling 3/376 129/18722 0.481254265739491 0.626422667027385 ATM/DUSP1/TAOK3 3 GO:0007127 meiosis I 3/376 129/18722 0.481254265739491 0.626422667027385 MYBL1/ATM/CENPC 3 GO:0007498 mesoderm development 3/376 129/18722 0.481254265739491 0.626422667027385 IKZF3/EOMES/IKZF1 3 GO:0006941 striated muscle contraction 4/376 179/18722 0.485579202123766 0.629918744929727 CALM1/CXCR4/RCSD1/FLNA 4 GO:0000422 autophagy of mitochondrion 2/376 81/18722 0.486124604948968 0.629918744929727 TOMM7/VPS13C 2 GO:0006096 glycolytic process 2/376 81/18722 0.486124604948968 0.629918744929727 DDIT4/STAT3 2 GO:0010833 telomere maintenance via telomere lengthening 2/376 81/18722 0.486124604948968 0.629918744929727 ATM/TERF2IP 2 GO:0021954 central nervous system neuron development 2/376 81/18722 0.486124604948968 0.629918744929727 NR4A2/BTG2 2 GO:0044773 mitotic DNA damage checkpoint signaling 2/376 81/18722 0.486124604948968 0.629918744929727 ATM/TAOK3 2 GO:0051149 positive regulation of muscle cell differentiation 2/376 81/18722 0.486124604948968 0.629918744929727 HOPX/TGFB1 2 GO:0061726 mitochondrion disassembly 2/376 81/18722 0.486124604948968 0.629918744929727 TOMM7/VPS13C 2 GO:2001021 negative regulation of response to DNA damage stimulus 2/376 81/18722 0.486124604948968 0.629918744929727 CDKN2D/CD44 2 GO:0006282 regulation of DNA repair 3/376 130/18722 0.486358639954699 0.629918744929727 WAS/TERF2IP/ACTR2 3 GO:0006956 complement activation 3/376 130/18722 0.486358639954699 0.629918744929727 TRDC/TRBC1/TRBC2 3 GO:0006336 DNA replication-independent nucleosome assembly 1/376 33/18722 0.488329267037136 0.629918744929727 ATRX 1 GO:0006536 glutamate metabolic process 1/376 33/18722 0.488329267037136 0.629918744929727 GLS 1 GO:0006654 phosphatidic acid biosynthetic process 1/376 33/18722 0.488329267037136 0.629918744929727 DGKZ 1 GO:0009156 ribonucleoside monophosphate biosynthetic process 1/376 33/18722 0.488329267037136 0.629918744929727 APRT 1 GO:0009648 photoperiodism 1/376 33/18722 0.488329267037136 0.629918744929727 ID2 1 GO:0010984 regulation of lipoprotein particle clearance 1/376 33/18722 0.488329267037136 0.629918744929727 CSK 1 GO:0021696 cerebellar cortex morphogenesis 1/376 33/18722 0.488329267037136 0.629918744929727 RORA 1 GO:0060122 inner ear receptor cell stereocilium organization 1/376 33/18722 0.488329267037136 0.629918744929727 SLC9A3R1 1 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1/376 33/18722 0.488329267037136 0.629918744929727 ATF7IP 1 GO:0061842 microtubule organizing center localization 1/376 33/18722 0.488329267037136 0.629918744929727 SUN2 1 GO:0070570 regulation of neuron projection regeneration 1/376 33/18722 0.488329267037136 0.629918744929727 FLNA 1 GO:0071295 cellular response to vitamin 1/376 33/18722 0.488329267037136 0.629918744929727 PIM1 1 GO:1901976 regulation of cell cycle checkpoint 1/376 33/18722 0.488329267037136 0.629918744929727 DUSP1 1 GO:1903146 regulation of autophagy of mitochondrion 1/376 33/18722 0.488329267037136 0.629918744929727 VPS13C 1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 1/376 33/18722 0.488329267037136 0.629918744929727 CCND2 1 GO:2000036 regulation of stem cell population maintenance 1/376 33/18722 0.488329267037136 0.629918744929727 LBH 1 GO:0010721 negative regulation of cell development 4/376 180/18722 0.489903903656712 0.63152948325674 B2M/TNF/SEMA4D/SORL1 4 GO:0071897 DNA biosynthetic process 4/376 180/18722 0.489903903656712 0.63152948325674 ATM/CDKN2D/DUSP1/TERF2IP 4 GO:0006612 protein targeting to membrane 3/376 131/18722 0.491438763965318 0.632666182845717 FYN/ITGB2/RAB8B 3 GO:0006661 phosphatidylinositol biosynthetic process 3/376 131/18722 0.491438763965318 0.632666182845717 PIP4K2A/ATM/PIK3R1 3 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 3/376 131/18722 0.491438763965318 0.632666182845717 TGFB1/ZEB2/CFLAR 3 GO:1904950 negative regulation of establishment of protein localization 3/376 131/18722 0.491438763965318 0.632666182845717 SP100/UCP2/CSK 3 GO:0006757 ATP generation from ADP 2/376 82/18722 0.492586615180282 0.633722819994553 DDIT4/STAT3 2 GO:0072527 pyrimidine-containing compound metabolic process 2/376 82/18722 0.492586615180282 0.633722819994553 APOBEC3G/APOBEC3C 2 GO:0007569 cell aging 3/376 132/18722 0.49649414443346 0.638310509525386 B2M/ATM/ID2 3 GO:0002183 cytoplasmic translational initiation 1/376 34/18722 0.498623461247315 0.638310509525386 EIF4A2 1 GO:0007616 long-term memory 1/376 34/18722 0.498623461247315 0.638310509525386 CCND2 1 GO:0009112 nucleobase metabolic process 1/376 34/18722 0.498623461247315 0.638310509525386 APRT 1 GO:0009649 entrainment of circadian clock 1/376 34/18722 0.498623461247315 0.638310509525386 ID2 1 GO:0010661 positive regulation of muscle cell apoptotic process 1/376 34/18722 0.498623461247315 0.638310509525386 STK4 1 GO:0030851 granulocyte differentiation 1/376 34/18722 0.498623461247315 0.638310509525386 EVI2B 1 GO:0032212 positive regulation of telomere maintenance via telomerase 1/376 34/18722 0.498623461247315 0.638310509525386 ATM 1 GO:0034383 low-density lipoprotein particle clearance 1/376 34/18722 0.498623461247315 0.638310509525386 CSK 1 GO:0034724 DNA replication-independent nucleosome organization 1/376 34/18722 0.498623461247315 0.638310509525386 ATRX 1 GO:0043276 anoikis 1/376 34/18722 0.498623461247315 0.638310509525386 MCL1 1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 1/376 34/18722 0.498623461247315 0.638310509525386 GPR65 1 GO:0086019 cell-cell signaling involved in cardiac conduction 1/376 34/18722 0.498623461247315 0.638310509525386 FLNA 1 GO:1990000 amyloid fibril formation 1/376 34/18722 0.498623461247315 0.638310509525386 B2M 1 GO:2000352 negative regulation of endothelial cell apoptotic process 1/376 34/18722 0.498623461247315 0.638310509525386 TNFAIP3 1 GO:0050886 endocrine process 2/376 83/18722 0.49899714640782 0.638577920188342 CYBA/RAB8B 2 GO:0010594 regulation of endothelial cell migration 5/376 232/18722 0.49984150878873 0.639447291699019 TMSB4X/ETS1/TNF/TGFB1/SP100 5 GO:0010595 positive regulation of endothelial cell migration 3/376 133/18722 0.50152430552521 0.641176735041303 TMSB4X/ETS1/TGFB1 3 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 3/376 133/18722 0.50152430552521 0.641176735041303 PYHIN1/LAPTM5/RNF19A 3 GO:0007018 microtubule-based movement 8/376 382/18722 0.502339604210297 0.642007244826814 RASGRP1/SUN2/KIF2A/OFD1/SLC9A3R1/ACTR3/CDC42/ACTR2 8 GO:0044262 cellular carbohydrate metabolic process 6/376 283/18722 0.50428204579742 0.644277259302671 PLEK/RORA/DDIT4/GNPTAB/STAT3/PPP1R2 6 GO:0010660 regulation of muscle cell apoptotic process 2/376 84/18722 0.505355655963767 0.644833322877181 STK4/CFLAR 2 GO:0032508 DNA duplex unwinding 2/376 84/18722 0.505355655963767 0.644833322877181 ATRX/CHD9 2 GO:0042440 pigment metabolic process 2/376 84/18722 0.505355655963767 0.644833322877181 ZEB2/APRT 2 GO:0042552 myelination 3/376 134/18722 0.506528788649924 0.644833322877181 CST7/MBP/CXCR4 3 GO:0007051 spindle organization 4/376 184/18722 0.507049848153248 0.644833322877181 FLNA/SUN2/KIF2A/ATRX 4 GO:0000731 DNA synthesis involved in DNA repair 1/376 35/18722 0.508711088525301 0.644833322877181 CDKN2D 1 GO:0001569 branching involved in blood vessel morphogenesis 1/376 35/18722 0.508711088525301 0.644833322877181 STK4 1 GO:0003298 physiological muscle hypertrophy 1/376 35/18722 0.508711088525301 0.644833322877181 AKAP13 1 GO:0003301 physiological cardiac muscle hypertrophy 1/376 35/18722 0.508711088525301 0.644833322877181 AKAP13 1 GO:0006471 protein ADP-ribosylation 1/376 35/18722 0.508711088525301 0.644833322877181 PARP8 1 GO:0006691 leukotriene metabolic process 1/376 35/18722 0.508711088525301 0.644833322877181 ALOX5AP 1 GO:0010664 negative regulation of striated muscle cell apoptotic process 1/376 35/18722 0.508711088525301 0.644833322877181 CFLAR 1 GO:0010765 positive regulation of sodium ion transport 1/376 35/18722 0.508711088525301 0.644833322877181 MLLT6 1 GO:0010837 regulation of keratinocyte proliferation 1/376 35/18722 0.508711088525301 0.644833322877181 ZFP36 1 GO:0019068 virion assembly 1/376 35/18722 0.508711088525301 0.644833322877181 DDX6 1 GO:0021955 central nervous system neuron axonogenesis 1/376 35/18722 0.508711088525301 0.644833322877181 NR4A2 1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1/376 35/18722 0.508711088525301 0.644833322877181 LBH 1 GO:0042462 eye photoreceptor cell development 1/376 35/18722 0.508711088525301 0.644833322877181 PRDM1 1 GO:0046627 negative regulation of insulin receptor signaling pathway 1/376 35/18722 0.508711088525301 0.644833322877181 PIP4K2A 1 GO:0050654 chondroitin sulfate proteoglycan metabolic process 1/376 35/18722 0.508711088525301 0.644833322877181 CHST12 1 GO:0061049 cell growth involved in cardiac muscle cell development 1/376 35/18722 0.508711088525301 0.644833322877181 AKAP13 1 GO:0071108 protein K48-linked deubiquitination 1/376 35/18722 0.508711088525301 0.644833322877181 TNFAIP3 1 GO:0098801 regulation of renal system process 1/376 35/18722 0.508711088525301 0.644833322877181 CYBA 1 GO:1905207 regulation of cardiocyte differentiation 1/376 35/18722 0.508711088525301 0.644833322877181 TGFB1 1 GO:0009259 ribonucleotide metabolic process 8/376 385/18722 0.511201899184296 0.647302928124879 TMSB4X/GIMAP7/RORA/DDIT4/TGFB1/STAT3/GUK1/APRT 8 GO:0002040 sprouting angiogenesis 4/376 185/18722 0.511296406524287 0.647302928124879 KLF2/JAK1/RNF213/CDC42 4 GO:0061982 meiosis I cell cycle process 3/376 135/18722 0.511507152198104 0.647302928124879 MYBL1/ATM/CENPC 3 GO:0044774 mitotic DNA integrity checkpoint signaling 2/376 85/18722 0.511661643573292 0.647302928124879 ATM/TAOK3 2 GO:0097006 regulation of plasma lipoprotein particle levels 2/376 85/18722 0.511661643573292 0.647302928124879 PRKACB/CSK 2 GO:0097194 execution phase of apoptosis 2/376 85/18722 0.511661643573292 0.647302928124879 CASP8/CFLAR 2 GO:0016072 rRNA metabolic process 5/376 236/18722 0.51493194878147 0.651227578827741 ISG20/RPS27/RPL35A/LYAR/DDX17 5 GO:0007272 ensheathment of neurons 3/376 136/18722 0.516458971278133 0.651819849805283 CST7/MBP/CXCR4 3 GO:0008366 axon ensheathment 3/376 136/18722 0.516458971278133 0.651819849805283 CST7/MBP/CXCR4 3 GO:0043624 cellular protein complex disassembly 3/376 136/18722 0.516458971278133 0.651819849805283 PLEK/CFL1/KIF2A 3 GO:0032413 negative regulation of ion transmembrane transporter activity 2/376 86/18722 0.517914649878966 0.651819849805283 CALM1/SLC9A3R1 2 GO:0046928 regulation of neurotransmitter secretion 2/376 86/18722 0.517914649878966 0.651819849805283 CALM1/RAP1B 2 GO:0048864 stem cell development 2/376 86/18722 0.517914649878966 0.651819849805283 PTPRC/SEMA4D 2 GO:0007031 peroxisome organization 1/376 36/18722 0.51859628308379 0.651819849805283 RAB8B 1 GO:0009225 nucleotide-sugar metabolic process 1/376 36/18722 0.51859628308379 0.651819849805283 GUK1 1 GO:0010762 regulation of fibroblast migration 1/376 36/18722 0.51859628308379 0.651819849805283 TGFB1 1 GO:0017004 cytochrome complex assembly 1/376 36/18722 0.51859628308379 0.651819849805283 CYBA 1 GO:0042755 eating behavior 1/376 36/18722 0.51859628308379 0.651819849805283 STAT3 1 GO:0044060 regulation of endocrine process 1/376 36/18722 0.51859628308379 0.651819849805283 RAB8B 1 GO:0044743 protein transmembrane import into intracellular organelle 1/376 36/18722 0.51859628308379 0.651819849805283 TOMM7 1 GO:0045746 negative regulation of Notch signaling pathway 1/376 36/18722 0.51859628308379 0.651819849805283 NFKBIA 1 GO:0051354 negative regulation of oxidoreductase activity 1/376 36/18722 0.51859628308379 0.651819849805283 GZMA 1 GO:0070306 lens fiber cell differentiation 1/376 36/18722 0.51859628308379 0.651819849805283 VIM 1 GO:0070897 transcription preinitiation complex assembly 1/376 36/18722 0.51859628308379 0.651819849805283 ATF7IP 1 GO:0097009 energy homeostasis 1/376 36/18722 0.51859628308379 0.651819849805283 STAT3 1 GO:1903539 protein localization to postsynaptic membrane 1/376 36/18722 0.51859628308379 0.651819849805283 VAMP2 1 GO:0048285 organelle fission 10/376 488/18722 0.519259835616519 0.652442238331391 MYBL1/ATM/FLNA/DUSP1/KIF2A/ACTR3/CDC42/ACTR2/ATRX/CENPC 10 GO:0000086 G2/M transition of mitotic cell cycle 3/376 137/18722 0.521383837452087 0.654050621601436 CALM1/ATM/TAOK3 3 GO:0006986 response to unfolded protein 3/376 137/18722 0.521383837452087 0.654050621601436 PIK3R1/XBP1/PPP1R15A 3 GO:0055123 digestive system development 3/376 137/18722 0.521383837452087 0.654050621601436 PRDM1/TNF/ID2 3 GO:0060048 cardiac muscle contraction 3/376 137/18722 0.521383837452087 0.654050621601436 CALM1/CXCR4/FLNA 3 GO:0090090 negative regulation of canonical Wnt signaling pathway 3/376 137/18722 0.521383837452087 0.654050621601436 STK4/CYLD/SLC9A3R1 3 GO:0019915 lipid storage 2/376 87/18722 0.524114255007095 0.657050384390972 TNF/NFKBIA 2 GO:0150104 transport across blood-brain barrier 2/376 87/18722 0.524114255007095 0.657050384390972 SLC2A3/SLC9A3R1 2 GO:0007224 smoothened signaling pathway 3/376 138/18722 0.52628135847088 0.65759620924053 CD3E/RORA/PRKACB 3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 1/376 37/18722 0.528283096610521 0.65759620924053 PABPC1 1 GO:0001990 regulation of systemic arterial blood pressure by hormone 1/376 37/18722 0.528283096610521 0.65759620924053 CYBA 1 GO:0016202 regulation of striated muscle tissue development 1/376 37/18722 0.528283096610521 0.65759620924053 TGFB1 1 GO:0021532 neural tube patterning 1/376 37/18722 0.528283096610521 0.65759620924053 PRKACB 1 GO:0031646 positive regulation of nervous system process 1/376 37/18722 0.528283096610521 0.65759620924053 CST7 1 GO:0032885 regulation of polysaccharide biosynthetic process 1/376 37/18722 0.528283096610521 0.65759620924053 TGFB1 1 GO:0033260 nuclear DNA replication 1/376 37/18722 0.528283096610521 0.65759620924053 ATRX 1 GO:0042401 cellular biogenic amine biosynthetic process 1/376 37/18722 0.528283096610521 0.65759620924053 NR4A2 1 GO:0046473 phosphatidic acid metabolic process 1/376 37/18722 0.528283096610521 0.65759620924053 DGKZ 1 GO:0048009 insulin-like growth factor receptor signaling pathway 1/376 37/18722 0.528283096610521 0.65759620924053 PIK3R1 1 GO:0048846 axon extension involved in axon guidance 1/376 37/18722 0.528283096610521 0.65759620924053 SEMA4D 1 GO:0050775 positive regulation of dendrite morphogenesis 1/376 37/18722 0.528283096610521 0.65759620924053 ACTR2 1 GO:0051567 histone H3-K9 methylation 1/376 37/18722 0.528283096610521 0.65759620924053 ATRX 1 GO:0060306 regulation of membrane repolarization 1/376 37/18722 0.528283096610521 0.65759620924053 FLNA 1 GO:0062237 protein localization to postsynapse 1/376 37/18722 0.528283096610521 0.65759620924053 VAMP2 1 GO:0071542 dopaminergic neuron differentiation 1/376 37/18722 0.528283096610521 0.65759620924053 NR4A2 1 GO:0097484 dendrite extension 1/376 37/18722 0.528283096610521 0.65759620924053 CXCR4 1 GO:1900016 negative regulation of cytokine production involved in inflammatory response 1/376 37/18722 0.528283096610521 0.65759620924053 PYCARD 1 GO:1900077 negative regulation of cellular response to insulin stimulus 1/376 37/18722 0.528283096610521 0.65759620924053 PIP4K2A 1 GO:1902284 neuron projection extension involved in neuron projection guidance 1/376 37/18722 0.528283096610521 0.65759620924053 SEMA4D 1 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1/376 37/18722 0.528283096610521 0.65759620924053 ATM 1 GO:0010232 vascular transport 2/376 88/18722 0.530260077174868 0.659633322328287 SLC2A3/SLC9A3R1 2 GO:0050829 defense response to Gram-negative bacterium 2/376 88/18722 0.530260077174868 0.659633322328287 RPL30/PYCARD 2 GO:0051783 regulation of nuclear division 3/376 139/18722 0.53115115800895 0.660529761644635 ATM/DUSP1/CDC42 3 GO:0009755 hormone-mediated signaling pathway 4/376 190/18722 0.532273669197124 0.661713335944451 DDX5/LBH/PRMT2/DDX17 4 GO:0071824 protein-DNA complex subunit organization 5/376 241/18722 0.533525201796401 0.663056496780325 ANP32E/ATRX/ATF7IP/HP1BP3/CENPC 5 GO:0010657 muscle cell apoptotic process 2/376 89/18722 0.536351771337282 0.663867493519007 STK4/CFLAR 2 GO:0014910 regulation of smooth muscle cell migration 2/376 89/18722 0.536351771337282 0.663867493519007 CCL5/SORL1 2 GO:1900407 regulation of cellular response to oxidative stress 2/376 89/18722 0.536351771337282 0.663867493519007 FYN/MCL1 2 GO:0006882 cellular zinc ion homeostasis 1/376 38/18722 0.537775499911268 0.663867493519007 LCK 1 GO:0009309 amine biosynthetic process 1/376 38/18722 0.537775499911268 0.663867493519007 NR4A2 1 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/376 38/18722 0.537775499911268 0.663867493519007 ROCK1 1 GO:0032373 positive regulation of sterol transport 1/376 38/18722 0.537775499911268 0.663867493519007 NFKBIA 1 GO:0032376 positive regulation of cholesterol transport 1/376 38/18722 0.537775499911268 0.663867493519007 NFKBIA 1 GO:0032941 secretion by tissue 1/376 38/18722 0.537775499911268 0.663867493519007 CYBA 1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 1/376 38/18722 0.537775499911268 0.663867493519007 LBH 1 GO:0035136 forelimb morphogenesis 1/376 38/18722 0.537775499911268 0.663867493519007 ATRX 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/376 38/18722 0.537775499911268 0.663867493519007 EPC1 1 GO:0042491 inner ear auditory receptor cell differentiation 1/376 38/18722 0.537775499911268 0.663867493519007 SLC9A3R1 1 GO:0046676 negative regulation of insulin secretion 1/376 38/18722 0.537775499911268 0.663867493519007 UCP2 1 GO:0048713 regulation of oligodendrocyte differentiation 1/376 38/18722 0.537775499911268 0.663867493519007 CXCR4 1 GO:0051930 regulation of sensory perception of pain 1/376 38/18722 0.537775499911268 0.663867493519007 CCL3 1 GO:0071392 cellular response to estradiol stimulus 1/376 38/18722 0.537775499911268 0.663867493519007 CFLAR 1 GO:0098926 postsynaptic signal transduction 1/376 38/18722 0.537775499911268 0.663867493519007 STAT3 1 GO:0099622 cardiac muscle cell membrane repolarization 1/376 38/18722 0.537775499911268 0.663867493519007 FLNA 1 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 1/376 38/18722 0.537775499911268 0.663867493519007 GZMB 1 GO:2000279 negative regulation of DNA biosynthetic process 1/376 38/18722 0.537775499911268 0.663867493519007 DUSP1 1 GO:0008584 male gonad development 3/376 141/18722 0.540806165364917 0.667396143563393 FLNA/ATRX/SF1 3 GO:0032392 DNA geometric change 2/376 90/18722 0.542389027872806 0.668710621383113 ATRX/CHD9 2 GO:0046031 ADP metabolic process 2/376 90/18722 0.542389027872806 0.668710621383113 DDIT4/STAT3 2 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 2/376 90/18722 0.542389027872806 0.668710621383113 TNF/JUN 2 GO:0019693 ribose phosphate metabolic process 8/376 396/18722 0.543234077049411 0.669539455650912 TMSB4X/GIMAP7/RORA/DDIT4/TGFB1/STAT3/GUK1/APRT 8 GO:0007059 chromosome segregation 7/376 346/18722 0.545397754306062 0.670650068021446 ATM/DUSP1/ACTR3/CDC42/ACTR2/ATRX/CENPC 7 GO:0046546 development of primary male sexual characteristics 3/376 142/18722 0.545590697759298 0.670650068021446 FLNA/ATRX/SF1 3 GO:0010463 mesenchymal cell proliferation 1/376 39/18722 0.547077384520204 0.670650068021446 STAT1 1 GO:0014742 positive regulation of muscle hypertrophy 1/376 39/18722 0.547077384520204 0.670650068021446 ROCK1 1 GO:0016572 histone phosphorylation 1/376 39/18722 0.547077384520204 0.670650068021446 ATM 1 GO:0017158 regulation of calcium ion-dependent exocytosis 1/376 39/18722 0.547077384520204 0.670650068021446 RAP1B 1 GO:0021587 cerebellum morphogenesis 1/376 39/18722 0.547077384520204 0.670650068021446 RORA 1 GO:0046326 positive regulation of glucose import 1/376 39/18722 0.547077384520204 0.670650068021446 PIK3R1 1 GO:0046461 neutral lipid catabolic process 1/376 39/18722 0.547077384520204 0.670650068021446 SORL1 1 GO:0046464 acylglycerol catabolic process 1/376 39/18722 0.547077384520204 0.670650068021446 SORL1 1 GO:0046621 negative regulation of organ growth 1/376 39/18722 0.547077384520204 0.670650068021446 STK4 1 GO:0051154 negative regulation of striated muscle cell differentiation 1/376 39/18722 0.547077384520204 0.670650068021446 XBP1 1 GO:0051931 regulation of sensory perception 1/376 39/18722 0.547077384520204 0.670650068021446 CCL3 1 GO:0090207 regulation of triglyceride metabolic process 1/376 39/18722 0.547077384520204 0.670650068021446 SORL1 1 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 1/376 39/18722 0.547077384520204 0.670650068021446 CALM1 1 GO:1901861 regulation of muscle tissue development 1/376 39/18722 0.547077384520204 0.670650068021446 TGFB1 1 GO:2000785 regulation of autophagosome assembly 1/376 39/18722 0.547077384520204 0.670650068021446 PIP4K2A 1 GO:0051983 regulation of chromosome segregation 2/376 91/18722 0.548371571306782 0.671599190522686 ATM/DUSP1 2 GO:0060191 regulation of lipase activity 2/376 91/18722 0.548371571306782 0.671599190522686 CCL5/TXK 2 GO:1990874 vascular associated smooth muscle cell proliferation 2/376 91/18722 0.548371571306782 0.671599190522686 TNF/JUN 2 GO:0034763 negative regulation of transmembrane transport 3/376 143/18722 0.550346157295373 0.67359171178761 TNF/CALM1/SLC9A3R1 3 GO:0062013 positive regulation of small molecule metabolic process 3/376 143/18722 0.550346157295373 0.67359171178761 TMSB4X/TNF/STAT3 3 GO:0031058 positive regulation of histone modification 2/376 92/18722 0.554299159071584 0.677324382959896 KMT2A/KMT2E 2 GO:0032465 regulation of cytokinesis 2/376 92/18722 0.554299159071584 0.677324382959896 CALM1/CDC42 2 GO:0034502 protein localization to chromosome 2/376 92/18722 0.554299159071584 0.677324382959896 TERF2IP/ATRX 2 GO:0035249 synaptic transmission, glutamatergic 2/376 92/18722 0.554299159071584 0.677324382959896 TNF/DGKZ 2 GO:0070509 calcium ion import 2/376 92/18722 0.554299159071584 0.677324382959896 FYN/CCL3 2 GO:0010821 regulation of mitochondrion organization 3/376 144/18722 0.55507224328389 0.677324382959896 GZMB/VPS13C/PYCARD 3 GO:0009187 cyclic nucleotide metabolic process 1/376 40/18722 0.556192564278294 0.677324382959896 RORA 1 GO:0010863 positive regulation of phospholipase C activity 1/376 40/18722 0.556192564278294 0.677324382959896 TXK 1 GO:0034122 negative regulation of toll-like receptor signaling pathway 1/376 40/18722 0.556192564278294 0.677324382959896 TNFAIP3 1 GO:0035329 hippo signaling 1/376 40/18722 0.556192564278294 0.677324382959896 STK4 1 GO:0055069 zinc ion homeostasis 1/376 40/18722 0.556192564278294 0.677324382959896 LCK 1 GO:0072210 metanephric nephron development 1/376 40/18722 0.556192564278294 0.677324382959896 STAT1 1 GO:0097352 autophagosome maturation 1/376 40/18722 0.556192564278294 0.677324382959896 CALM1 1 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 1/376 40/18722 0.556192564278294 0.677324382959896 CALM1 1 GO:1901998 toxin transport 1/376 40/18722 0.556192564278294 0.677324382959896 RAB29 1 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 1/376 40/18722 0.556192564278294 0.677324382959896 GZMB 1 GO:0045664 regulation of neuron differentiation 4/376 196/18722 0.556846421520352 0.677694686994776 B2M/ID2/DDX6/ROCK1 4 GO:0090276 regulation of peptide hormone secretion 4/376 196/18722 0.556846421520352 0.677694686994776 CCL5/TNF/RAB8B/UCP2 4 GO:0003012 muscle system process 9/376 452/18722 0.557672209920575 0.678486597627073 CYBA/CALM1/CXCR4/TPM3/RCSD1/FLNA/AKAP13/CFLAR/ROCK1 9 GO:0021537 telencephalon development 5/376 248/18722 0.559001847613198 0.679890822191194 CXCR4/FLNA/ID2/SUN2/BTG2 5 GO:0007269 neurotransmitter secretion 3/376 145/18722 0.559768669368891 0.680396359411686 CALM1/VAMP2/RAP1B 3 GO:0099643 signal release from synapse 3/376 145/18722 0.559768669368891 0.680396359411686 CALM1/VAMP2/RAP1B 3 GO:0033273 response to vitamin 2/376 93/18722 0.560171580302583 0.680459208047809 CDKN2D/PIM1 2 GO:1901992 positive regulation of mitotic cell cycle phase transition 2/376 93/18722 0.560171580302583 0.680459208047809 CCND2/KMT2E 2 GO:0001953 negative regulation of cell-matrix adhesion 1/376 41/18722 0.565124776880337 0.684544704723759 PIK3R1 1 GO:0044786 cell cycle DNA replication 1/376 41/18722 0.565124776880337 0.684544704723759 ATRX 1 GO:0048286 lung alveolus development 1/376 41/18722 0.565124776880337 0.684544704723759 HOPX 1 GO:0048634 regulation of muscle organ development 1/376 41/18722 0.565124776880337 0.684544704723759 TGFB1 1 GO:0050892 intestinal absorption 1/376 41/18722 0.565124776880337 0.684544704723759 EPB41 1 GO:0055023 positive regulation of cardiac muscle tissue growth 1/376 41/18722 0.565124776880337 0.684544704723759 PIM1 1 GO:0071470 cellular response to osmotic stress 1/376 41/18722 0.565124776880337 0.684544704723759 RCSD1 1 GO:1901385 regulation of voltage-gated calcium channel activity 1/376 41/18722 0.565124776880337 0.684544704723759 CALM1 1 GO:1902116 negative regulation of organelle assembly 1/376 41/18722 0.565124776880337 0.684544704723759 ODF2L 1 GO:0010389 regulation of G2/M transition of mitotic cell cycle 2/376 94/18722 0.565988654668979 0.685376886513216 ATM/TAOK3 2 GO:1902850 microtubule cytoskeleton organization involved in mitosis 3/376 147/18722 0.569071466493428 0.688679554235488 FLNA/SUN2/KIF2A 3 GO:1903531 negative regulation of secretion by cell 3/376 147/18722 0.569071466493428 0.688679554235488 HLA-F/UCP2/RAP1B 3 GO:0006302 double-strand break repair 5/376 251/18722 0.569707446253402 0.689115596805461 ATM/WAS/TERF2IP/SAMHD1/ACTR2 5 GO:0060070 canonical Wnt signaling pathway 6/376 303/18722 0.571049216318568 0.689115596805461 STK4/TGFB1/NR4A2/CYLD/ZEB2/SLC9A3R1 6 GO:0008593 regulation of Notch signaling pathway 2/376 95/18722 0.571750231238597 0.689115596805461 STAT3/NFKBIA 2 GO:0030516 regulation of axon extension 2/376 95/18722 0.571750231238597 0.689115596805461 SEMA4D/MACF1 2 GO:0036473 cell death in response to oxidative stress 2/376 95/18722 0.571750231238597 0.689115596805461 FYN/MCL1 2 GO:0048709 oligodendrocyte differentiation 2/376 95/18722 0.571750231238597 0.689115596805461 CXCR4/CSK 2 GO:1901379 regulation of potassium ion transmembrane transport 2/376 95/18722 0.571750231238597 0.689115596805461 FLNA/VAMP2 2 GO:0002791 regulation of peptide secretion 4/376 200/18722 0.572839184646925 0.689115596805461 CCL5/TNF/RAB8B/UCP2 4 GO:0044839 cell cycle G2/M phase transition 3/376 148/18722 0.573677334124742 0.689115596805461 CALM1/ATM/TAOK3 3 GO:0000413 protein peptidyl-prolyl isomerization 1/376 42/18722 0.573877685391283 0.689115596805461 FKBP11 1 GO:0009124 nucleoside monophosphate biosynthetic process 1/376 42/18722 0.573877685391283 0.689115596805461 APRT 1 GO:0016601 Rac protein signal transduction 1/376 42/18722 0.573877685391283 0.689115596805461 RAC2 1 GO:0021575 hindbrain morphogenesis 1/376 42/18722 0.573877685391283 0.689115596805461 RORA 1 GO:0021795 cerebral cortex cell migration 1/376 42/18722 0.573877685391283 0.689115596805461 SUN2 1 GO:0021879 forebrain neuron differentiation 1/376 42/18722 0.573877685391283 0.689115596805461 B2M 1 GO:0032467 positive regulation of cytokinesis 1/376 42/18722 0.573877685391283 0.689115596805461 CDC42 1 GO:0033003 regulation of mast cell activation 1/376 42/18722 0.573877685391283 0.689115596805461 RAC2 1 GO:0045773 positive regulation of axon extension 1/376 42/18722 0.573877685391283 0.689115596805461 MACF1 1 GO:0048489 synaptic vesicle transport 1/376 42/18722 0.573877685391283 0.689115596805461 RAB27A 1 GO:0051602 response to electrical stimulus 1/376 42/18722 0.573877685391283 0.689115596805461 BTG2 1 GO:0060999 positive regulation of dendritic spine development 1/376 42/18722 0.573877685391283 0.689115596805461 ACTR2 1 GO:0090317 negative regulation of intracellular protein transport 1/376 42/18722 0.573877685391283 0.689115596805461 SP100 1 GO:1900274 regulation of phospholipase C activity 1/376 42/18722 0.573877685391283 0.689115596805461 TXK 1 GO:1903432 regulation of TORC1 signaling 1/376 42/18722 0.573877685391283 0.689115596805461 ATM 1 GO:1904037 positive regulation of epithelial cell apoptotic process 1/376 42/18722 0.573877685391283 0.689115596805461 ITGA4 1 GO:0060828 regulation of canonical Wnt signaling pathway 5/376 253/18722 0.576769883539878 0.692179752979903 STK4/TGFB1/CYLD/ZEB2/SLC9A3R1 5 GO:0065004 protein-DNA complex assembly 4/376 201/18722 0.576786689644414 0.692179752979903 ATRX/ATF7IP/HP1BP3/CENPC 4 GO:0042632 cholesterol homeostasis 2/376 96/18722 0.577456187375763 0.692339952376573 RORA/XBP1 2 GO:0051304 chromosome separation 2/376 96/18722 0.577456187375763 0.692339952376573 ATM/DUSP1 2 GO:0055017 cardiac muscle tissue growth 2/376 96/18722 0.577456187375763 0.692339952376573 AKAP13/PIM1 2 GO:0006839 mitochondrial transport 5/376 254/18722 0.580278212094092 0.695293157657578 GZMB/RAC2/UCP2/TOMM7/STAT3 5 GO:0009165 nucleotide biosynthetic process 5/376 254/18722 0.580278212094092 0.695293157657578 TMSB4X/TGFB1/STAT3/GUK1/APRT 5 GO:0000819 sister chromatid segregation 4/376 202/18722 0.580713517151733 0.6953212134822 ATM/DUSP1/ATRX/CENPC 4 GO:0090087 regulation of peptide transport 4/376 202/18722 0.580713517151733 0.6953212134822 CCL5/TNF/RAB8B/UCP2 4 GO:0009268 response to pH 1/376 43/18722 0.582454879732444 0.6953212134822 GPR65 1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 1/376 43/18722 0.582454879732444 0.6953212134822 FXYD5 1 GO:0021983 pituitary gland development 1/376 43/18722 0.582454879732444 0.6953212134822 ETS1 1 GO:0030517 negative regulation of axon extension 1/376 43/18722 0.582454879732444 0.6953212134822 SEMA4D 1 GO:0032365 intracellular lipid transport 1/376 43/18722 0.582454879732444 0.6953212134822 PIP4K2A 1 GO:0035794 positive regulation of mitochondrial membrane permeability 1/376 43/18722 0.582454879732444 0.6953212134822 GZMB 1 GO:0046717 acid secretion 1/376 43/18722 0.582454879732444 0.6953212134822 SLC9A3R1 1 GO:0061383 trabecula morphogenesis 1/376 43/18722 0.582454879732444 0.6953212134822 SEMA4D 1 GO:0090278 negative regulation of peptide hormone secretion 1/376 43/18722 0.582454879732444 0.6953212134822 UCP2 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/376 43/18722 0.582454879732444 0.6953212134822 FLNA 1 GO:0014909 smooth muscle cell migration 2/376 97/18722 0.583106427671386 0.695456265689941 CCL5/SORL1 2 GO:0043255 regulation of carbohydrate biosynthetic process 2/376 97/18722 0.583106427671386 0.695456265689941 PLEK/TGFB1 2 GO:0055092 sterol homeostasis 2/376 97/18722 0.583106427671386 0.695456265689941 RORA/XBP1 2 GO:1901293 nucleoside phosphate biosynthetic process 5/376 256/18722 0.587248297865454 0.700038919893547 TMSB4X/TGFB1/STAT3/GUK1/APRT 5 GO:0030902 hindbrain development 3/376 151/18722 0.587310071890044 0.700038919893547 CD3E/RORA/FLNA 3 GO:0061337 cardiac conduction 2/376 98/18722 0.588700882904402 0.701265269368139 CALM1/FLNA 2 GO:1902882 regulation of response to oxidative stress 2/376 98/18722 0.588700882904402 0.701265269368139 FYN/MCL1 2 GO:0002066 columnar/cuboidal epithelial cell development 1/376 44/18722 0.590859878138172 0.701895164863709 PRDM1 1 GO:0002792 negative regulation of peptide secretion 1/376 44/18722 0.590859878138172 0.701895164863709 UCP2 1 GO:0006378 mRNA polyadenylation 1/376 44/18722 0.590859878138172 0.701895164863709 PABPC1 1 GO:0006775 fat-soluble vitamin metabolic process 1/376 44/18722 0.590859878138172 0.701895164863709 TNF 1 GO:0032620 interleukin-17 production 1/376 44/18722 0.590859878138172 0.701895164863709 TGFB1 1 GO:0032660 regulation of interleukin-17 production 1/376 44/18722 0.590859878138172 0.701895164863709 TGFB1 1 GO:0032881 regulation of polysaccharide metabolic process 1/376 44/18722 0.590859878138172 0.701895164863709 TGFB1 1 GO:0044058 regulation of digestive system process 1/376 44/18722 0.590859878138172 0.701895164863709 EPB41 1 GO:0046006 regulation of activated T cell proliferation 1/376 44/18722 0.590859878138172 0.701895164863709 PYCARD 1 GO:0008643 carbohydrate transport 3/376 152/18722 0.591792009706986 0.702356519943207 TNF/SLC2A3/PIK3R1 3 GO:0030509 BMP signaling pathway 3/376 152/18722 0.591792009706986 0.702356519943207 DDX5/TGFB1/SORL1 3 GO:0090501 RNA phosphodiester bond hydrolysis 3/376 152/18722 0.591792009706986 0.702356519943207 ISG20/SAMHD1/CNOT6L 3 GO:0003300 cardiac muscle hypertrophy 2/376 99/18722 0.594239509033778 0.704182904436052 AKAP13/ROCK1 2 GO:0006165 nucleoside diphosphate phosphorylation 2/376 99/18722 0.594239509033778 0.704182904436052 DDIT4/STAT3 2 GO:0010717 regulation of epithelial to mesenchymal transition 2/376 99/18722 0.594239509033778 0.704182904436052 TGFB1/GLIPR2 2 GO:0021549 cerebellum development 2/376 99/18722 0.594239509033778 0.704182904436052 CD3E/RORA 2 GO:0060291 long-term synaptic potentiation 2/376 99/18722 0.594239509033778 0.704182904436052 TYROBP/VAMP2 2 GO:0008016 regulation of heart contraction 4/376 206/18722 0.596210377950456 0.70630241961419 HOPX/CELF2/CALM1/FLNA 4 GO:0061564 axon development 9/376 467/18722 0.597059557006789 0.706481283707098 RAC2/FYN/ITGA4/NR4A2/FLNA/ACTB/SEMA4D/EMB/MACF1 9 GO:0003009 skeletal muscle contraction 1/376 45/18722 0.599096128583619 0.706481283707098 RCSD1 1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 1/376 45/18722 0.599096128583619 0.706481283707098 MCL1 1 GO:0030850 prostate gland development 1/376 45/18722 0.599096128583619 0.706481283707098 CRIP1 1 GO:0042551 neuron maturation 1/376 45/18722 0.599096128583619 0.706481283707098 NR4A2 1 GO:0043631 RNA polyadenylation 1/376 45/18722 0.599096128583619 0.706481283707098 PABPC1 1 GO:0044088 regulation of vacuole organization 1/376 45/18722 0.599096128583619 0.706481283707098 PIP4K2A 1 GO:0045910 negative regulation of DNA recombination 1/376 45/18722 0.599096128583619 0.706481283707098 TERF2IP 1 GO:0048546 digestive tract morphogenesis 1/376 45/18722 0.599096128583619 0.706481283707098 ID2 1 GO:0051180 vitamin transport 1/376 45/18722 0.599096128583619 0.706481283707098 SLC2A3 1 GO:0060119 inner ear receptor cell development 1/376 45/18722 0.599096128583619 0.706481283707098 SLC9A3R1 1 GO:0060421 positive regulation of heart growth 1/376 45/18722 0.599096128583619 0.706481283707098 PIM1 1 GO:0085029 extracellular matrix assembly 1/376 45/18722 0.599096128583619 0.706481283707098 TGFB1 1 GO:1901985 positive regulation of protein acetylation 1/376 45/18722 0.599096128583619 0.706481283707098 TERF2IP 1 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 1/376 45/18722 0.599096128583619 0.706481283707098 GZMB 1 GO:0006626 protein targeting to mitochondrion 2/376 100/18722 0.599722286220242 0.706574599909832 RAC2/TOMM7 2 GO:0045807 positive regulation of endocytosis 2/376 100/18722 0.599722286220242 0.706574599909832 B2M/CDC42 2 GO:0051588 regulation of neurotransmitter transport 2/376 100/18722 0.599722286220242 0.706574599909832 CALM1/RAP1B 2 GO:0007605 sensory perception of sound 3/376 154/18722 0.60066131804003 0.707250868248288 MBP/CDKN2D/SLC9A3R1 3 GO:0051168 nuclear export 3/376 154/18722 0.60066131804003 0.707250868248288 TGFB1/SP100/AKAP13 3 GO:0007409 axonogenesis 8/376 418/18722 0.604603094669905 0.710378068980515 RAC2/FYN/ITGA4/NR4A2/ACTB/SEMA4D/EMB/MACF1 8 GO:0010970 transport along microtubule 3/376 155/18722 0.605048362218166 0.710378068980515 RASGRP1/SUN2/CDC42 3 GO:0006476 protein deacetylation 2/376 101/18722 0.605149217876976 0.710378068980515 HOPX/FLNA 2 GO:0006576 cellular biogenic amine metabolic process 2/376 101/18722 0.605149217876976 0.710378068980515 ITGB2/NR4A2 2 GO:0006195 purine nucleotide catabolic process 1/376 46/18722 0.60716701018412 0.710378068980515 SAMHD1 1 GO:0006984 ER-nucleus signaling pathway 1/376 46/18722 0.60716701018412 0.710378068980515 PPP1R15A 1 GO:0007019 microtubule depolymerization 1/376 46/18722 0.60716701018412 0.710378068980515 KIF2A 1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 1/376 46/18722 0.60716701018412 0.710378068980515 ITGAL 1 GO:0010828 positive regulation of glucose transmembrane transport 1/376 46/18722 0.60716701018412 0.710378068980515 PIK3R1 1 GO:0010830 regulation of myotube differentiation 1/376 46/18722 0.60716701018412 0.710378068980515 XBP1 1 GO:0031057 negative regulation of histone modification 1/376 46/18722 0.60716701018412 0.710378068980515 MLLT6 1 GO:0031648 protein destabilization 1/376 46/18722 0.60716701018412 0.710378068980515 PYHIN1 1 GO:0034198 cellular response to amino acid starvation 1/376 46/18722 0.60716701018412 0.710378068980515 UCP2 1 GO:0043462 regulation of ATPase activity 1/376 46/18722 0.60716701018412 0.710378068980515 PFN1 1 GO:0043616 keratinocyte proliferation 1/376 46/18722 0.60716701018412 0.710378068980515 ZFP36 1 GO:0050919 negative chemotaxis 1/376 46/18722 0.60716701018412 0.710378068980515 SEMA4D 1 GO:0055010 ventricular cardiac muscle tissue morphogenesis 1/376 46/18722 0.60716701018412 0.710378068980515 TGFB1 1 GO:0060976 coronary vasculature development 1/376 46/18722 0.60716701018412 0.710378068980515 PRDM1 1 GO:0071827 plasma lipoprotein particle organization 1/376 46/18722 0.60716701018412 0.710378068980515 PRKACB 1 GO:0090329 regulation of DNA-dependent DNA replication 1/376 46/18722 0.60716701018412 0.710378068980515 ATRX 1 GO:1900271 regulation of long-term synaptic potentiation 1/376 46/18722 0.60716701018412 0.710378068980515 TYROBP 1 GO:0014897 striated muscle hypertrophy 2/376 102/18722 0.61052032974851 0.71335173794743 AKAP13/ROCK1 2 GO:1902749 regulation of cell cycle G2/M phase transition 2/376 102/18722 0.61052032974851 0.71335173794743 ATM/TAOK3 2 GO:1904063 negative regulation of cation transmembrane transport 2/376 102/18722 0.61052032974851 0.71335173794743 CALM1/SLC9A3R1 2 GO:1990542 mitochondrial transmembrane transport 2/376 102/18722 0.61052032974851 0.71335173794743 UCP2/TOMM7 2 GO:0044782 cilium organization 7/376 368/18722 0.610629087683 0.71335173794743 FLNA/CYLD/OFD1/SLC9A3R1/ACTR3/ODF2L/ACTR2 7 GO:0003018 vascular process in circulatory system 5/376 263/18722 0.611139362577487 0.713732679321206 KLF2/TGFB1/SLC2A3/SLC9A3R1/ROCK1 5 GO:1902600 proton transmembrane transport 3/376 157/18722 0.613726501482728 0.714262929041415 TMSB4X/UCP2/SLC9A3R1 3 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 1/376 47/18722 0.615075834566791 0.714262929041415 CYBA 1 GO:0006998 nuclear envelope organization 1/376 47/18722 0.615075834566791 0.714262929041415 SUN2 1 GO:0010761 fibroblast migration 1/376 47/18722 0.615075834566791 0.714262929041415 TGFB1 1 GO:0014911 positive regulation of smooth muscle cell migration 1/376 47/18722 0.615075834566791 0.714262929041415 CCL5 1 GO:0031641 regulation of myelination 1/376 47/18722 0.615075834566791 0.714262929041415 CST7 1 GO:0035315 hair cell differentiation 1/376 47/18722 0.615075834566791 0.714262929041415 SLC9A3R1 1 GO:0035850 epithelial cell differentiation involved in kidney development 1/376 47/18722 0.615075834566791 0.714262929041415 STAT1 1 GO:0042311 vasodilation 1/376 47/18722 0.615075834566791 0.714262929041415 KLF2 1 GO:0043114 regulation of vascular permeability 1/376 47/18722 0.615075834566791 0.714262929041415 TGFB1 1 GO:0045747 positive regulation of Notch signaling pathway 1/376 47/18722 0.615075834566791 0.714262929041415 STAT3 1 GO:0047496 vesicle transport along microtubule 1/376 47/18722 0.615075834566791 0.714262929041415 RASGRP1 1 GO:0048512 circadian behavior 1/376 47/18722 0.615075834566791 0.714262929041415 ID2 1 GO:0072583 clathrin-dependent endocytosis 1/376 47/18722 0.615075834566791 0.714262929041415 ITGA4 1 GO:0097028 dendritic cell differentiation 1/376 47/18722 0.615075834566791 0.714262929041415 HLA-B 1 GO:0120163 negative regulation of cold-induced thermogenesis 1/376 47/18722 0.615075834566791 0.714262929041415 LNPEP 1 GO:1903170 negative regulation of calcium ion transmembrane transport 1/376 47/18722 0.615075834566791 0.714262929041415 CALM1 1 GO:0030100 regulation of endocytosis 4/376 211/18722 0.615095585602891 0.714262929041415 B2M/CALM1/CDC42/ROCK1 4 GO:0046474 glycerophospholipid biosynthetic process 4/376 211/18722 0.615095585602891 0.714262929041415 PIP4K2A/ATM/DGKZ/PIK3R1 4 GO:0050773 regulation of dendrite development 2/376 103/18722 0.615835669017057 0.714908093900868 SEMA4D/ACTR2 2 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 2/376 104/18722 0.621095303435583 0.719935477359522 GPR65/SLC9A3R1 2 GO:0032006 regulation of TOR signaling 2/376 104/18722 0.621095303435583 0.719935477359522 DDIT4/ATM 2 GO:0032963 collagen metabolic process 2/376 104/18722 0.621095303435583 0.719935477359522 VIM/TGFB1 2 GO:0060419 heart growth 2/376 104/18722 0.621095303435583 0.719935477359522 AKAP13/PIM1 2 GO:1901890 positive regulation of cell junction assembly 2/376 104/18722 0.621095303435583 0.719935477359522 SEMA4D/ROCK1 2 GO:0035966 response to topologically incorrect protein 3/376 159/18722 0.622275866805942 0.721088212880689 PIK3R1/XBP1/PPP1R15A 3 GO:0090199 regulation of release of cytochrome c from mitochondria 1/376 48/18722 0.622825847214871 0.721509763216031 PYCARD 1 GO:0032412 regulation of ion transmembrane transporter activity 5/376 267/18722 0.624426822614126 0.723148218060292 TMSB4X/CALM1/FXYD5/VAMP2/SLC9A3R1 5 GO:0050708 regulation of protein secretion 5/376 268/18722 0.627706101553837 0.726728755160178 CCL5/TNF/TGFB1/UCP2/DNAJC1 5 GO:0007622 rhythmic behavior 1/376 49/18722 0.630420228785354 0.72758261312842 ID2 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/376 49/18722 0.630420228785354 0.72758261312842 TGFB1 1 GO:0021695 cerebellar cortex development 1/376 49/18722 0.630420228785354 0.72758261312842 RORA 1 GO:0030857 negative regulation of epithelial cell differentiation 1/376 49/18722 0.630420228785354 0.72758261312842 STAT1 1 GO:0042461 photoreceptor cell development 1/376 49/18722 0.630420228785354 0.72758261312842 PRDM1 1 GO:0043330 response to exogenous dsRNA 1/376 49/18722 0.630420228785354 0.72758261312842 NFKBIA 1 GO:0046580 negative regulation of Ras protein signal transduction 1/376 49/18722 0.630420228785354 0.72758261312842 RASA2 1 GO:0060986 endocrine hormone secretion 1/376 49/18722 0.630420228785354 0.72758261312842 RAB8B 1 GO:0086009 membrane repolarization 1/376 49/18722 0.630420228785354 0.72758261312842 FLNA 1 GO:1990928 response to amino acid starvation 1/376 49/18722 0.630420228785354 0.72758261312842 UCP2 1 GO:0002062 chondrocyte differentiation 2/376 106/18722 0.631447826567968 0.72758261312842 RUNX3/TGFB1 2 GO:0006090 pyruvate metabolic process 2/376 106/18722 0.631447826567968 0.72758261312842 DDIT4/STAT3 2 GO:0006766 vitamin metabolic process 2/376 106/18722 0.631447826567968 0.72758261312842 TNF/SLC2A3 2 GO:0046620 regulation of organ growth 2/376 106/18722 0.631447826567968 0.72758261312842 STK4/PIM1 2 GO:0090263 positive regulation of canonical Wnt signaling pathway 2/376 106/18722 0.631447826567968 0.72758261312842 TGFB1/ZEB2 2 GO:2000278 regulation of DNA biosynthetic process 2/376 106/18722 0.631447826567968 0.72758261312842 ATM/DUSP1 2 GO:0005976 polysaccharide metabolic process 2/376 107/18722 0.636540946199166 0.732577244680423 TGFB1/PPP1R2 2 GO:0021761 limbic system development 2/376 107/18722 0.636540946199166 0.732577244680423 ETS1/BTG2 2 GO:0007080 mitotic metaphase plate congression 1/376 50/18722 0.637862096400451 0.732577244680423 CENPC 1 GO:0007140 male meiotic nuclear division 1/376 50/18722 0.637862096400451 0.732577244680423 MYBL1 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/376 50/18722 0.637862096400451 0.732577244680423 CFLAR 1 GO:0038202 TORC1 signaling 1/376 50/18722 0.637862096400451 0.732577244680423 ATM 1 GO:0043268 positive regulation of potassium ion transport 1/376 50/18722 0.637862096400451 0.732577244680423 FLNA 1 GO:0046638 positive regulation of alpha-beta T cell differentiation 1/376 50/18722 0.637862096400451 0.732577244680423 RUNX3 1 GO:0060688 regulation of morphogenesis of a branching structure 1/376 50/18722 0.637862096400451 0.732577244680423 TNF 1 GO:0071825 protein-lipid complex subunit organization 1/376 50/18722 0.637862096400451 0.732577244680423 PRKACB 1 GO:1902930 regulation of alcohol biosynthetic process 1/376 50/18722 0.637862096400451 0.732577244680423 PLEK 1 GO:0060562 epithelial tube morphogenesis 6/376 325/18722 0.639049089013983 0.733723028127166 TNF/CXCR4/STK4/TGFB1/PRKACB/PFN1 6 GO:0007173 epidermal growth factor receptor signaling pathway 2/376 108/18722 0.641578821257128 0.736191274021726 TGFB1/CBLB 2 GO:0022037 metencephalon development 2/376 108/18722 0.641578821257128 0.736191274021726 CD3E/RORA 2 GO:0050806 positive regulation of synaptic transmission 3/376 164/18722 0.643080655305863 0.737477815717733 TNF/TYROBP/VAMP2 3 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 3/376 164/18722 0.643080655305863 0.737477815717733 PYHIN1/LAPTM5/RNF19A 3 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 5/376 273/18722 0.643842044914346 0.73789070440949 MBP/ITGAL/ITGB2/FXYD5/EMB 5 GO:0010656 negative regulation of muscle cell apoptotic process 1/376 51/18722 0.645154504913381 0.73789070440949 CFLAR 1 GO:0010874 regulation of cholesterol efflux 1/376 51/18722 0.645154504913381 0.73789070440949 NFKBIA 1 GO:0021872 forebrain generation of neurons 1/376 51/18722 0.645154504913381 0.73789070440949 B2M 1 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 1/376 51/18722 0.645154504913381 0.73789070440949 RUNX3 1 GO:0048013 ephrin receptor signaling pathway 1/376 51/18722 0.645154504913381 0.73789070440949 FYN 1 GO:0051293 establishment of spindle localization 1/376 51/18722 0.645154504913381 0.73789070440949 CFL1 1 GO:0060043 regulation of cardiac muscle cell proliferation 1/376 51/18722 0.645154504913381 0.73789070440949 PIM1 1 GO:0065002 intracellular protein transmembrane transport 1/376 51/18722 0.645154504913381 0.73789070440949 TOMM7 1 GO:0032410 negative regulation of transporter activity 2/376 109/18722 0.646561610231248 0.738422028445307 CALM1/SLC9A3R1 2 GO:0032414 positive regulation of ion transmembrane transporter activity 2/376 109/18722 0.646561610231248 0.738422028445307 TMSB4X/CALM1 2 GO:0034766 negative regulation of ion transmembrane transport 2/376 109/18722 0.646561610231248 0.738422028445307 CALM1/SLC9A3R1 2 GO:0043266 regulation of potassium ion transport 2/376 109/18722 0.646561610231248 0.738422028445307 FLNA/VAMP2 2 GO:0046661 male sex differentiation 3/376 165/18722 0.647143537703293 0.738422028445307 FLNA/ATRX/SF1 3 GO:0050796 regulation of insulin secretion 3/376 165/18722 0.647143537703293 0.738422028445307 CCL5/TNF/UCP2 3 GO:0071772 response to BMP 3/376 165/18722 0.647143537703293 0.738422028445307 DDX5/TGFB1/SORL1 3 GO:0071773 cellular response to BMP stimulus 3/376 165/18722 0.647143537703293 0.738422028445307 DDX5/TGFB1/SORL1 3 GO:0051236 establishment of RNA localization 3/376 166/18722 0.651173604517811 0.741685515427654 ATM/ZFP36/SRSF7 3 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 4/376 221/18722 0.651183659766582 0.741685515427654 PYHIN1/PSME1/LAPTM5/RNF19A 4 GO:0061387 regulation of extent of cell growth 2/376 110/18722 0.651489487502804 0.741685515427654 SEMA4D/MACF1 2 GO:0009117 nucleotide metabolic process 9/376 489/18722 0.651602350072134 0.741685515427654 TMSB4X/GIMAP7/RORA/DDIT4/TGFB1/SAMHD1/STAT3/GUK1/APRT 9 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 1/376 52/18722 0.652300448149018 0.741685515427654 TAPBP 1 GO:0010662 regulation of striated muscle cell apoptotic process 1/376 52/18722 0.652300448149018 0.741685515427654 CFLAR 1 GO:0030514 negative regulation of BMP signaling pathway 1/376 52/18722 0.652300448149018 0.741685515427654 SORL1 1 GO:0031103 axon regeneration 1/376 52/18722 0.652300448149018 0.741685515427654 FLNA 1 GO:0043090 amino acid import 1/376 52/18722 0.652300448149018 0.741685515427654 SLC9A3R1 1 GO:0048260 positive regulation of receptor-mediated endocytosis 1/376 52/18722 0.652300448149018 0.741685515427654 B2M 1 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 1/376 52/18722 0.652300448149018 0.741685515427654 CDC42 1 GO:0072523 purine-containing compound catabolic process 1/376 52/18722 0.652300448149018 0.741685515427654 SAMHD1 1 GO:0034728 nucleosome organization 3/376 167/18722 0.655170820923875 0.744730692601941 ANP32E/ATRX/HP1BP3 3 GO:0006805 xenobiotic metabolic process 2/376 111/18722 0.6563626426462 0.745291068035241 RORA/GUK1 2 GO:0015718 monocarboxylic acid transport 2/376 111/18722 0.6563626426462 0.745291068035241 EMB/SLC9A3R1 2 GO:0090288 negative regulation of cellular response to growth factor stimulus 2/376 111/18722 0.6563626426462 0.745291068035241 SORL1/CFLAR 2 GO:0046034 ATP metabolic process 5/376 277/18722 0.656433139407555 0.745291068035241 TMSB4X/DDIT4/TGFB1/STAT3/GUK1 5 GO:0007566 embryo implantation 1/376 53/18722 0.659302860119878 0.746580532719032 ARHGDIB 1 GO:0031279 regulation of cyclase activity 1/376 53/18722 0.659302860119878 0.746580532719032 CALM1 1 GO:0032210 regulation of telomere maintenance via telomerase 1/376 53/18722 0.659302860119878 0.746580532719032 ATM 1 GO:0034381 plasma lipoprotein particle clearance 1/376 53/18722 0.659302860119878 0.746580532719032 CSK 1 GO:0071320 cellular response to cAMP 1/376 53/18722 0.659302860119878 0.746580532719032 RAP1B 1 GO:0097479 synaptic vesicle localization 1/376 53/18722 0.659302860119878 0.746580532719032 RAB27A 1 GO:1903202 negative regulation of oxidative stress-induced cell death 1/376 53/18722 0.659302860119878 0.746580532719032 FYN 1 GO:1990090 cellular response to nerve growth factor stimulus 1/376 53/18722 0.659302860119878 0.746580532719032 CORO1A 1 GO:2000772 regulation of cellular senescence 1/376 53/18722 0.659302860119878 0.746580532719032 B2M 1 GO:0043542 endothelial cell migration 5/376 279/18722 0.6626211666509 0.75011890761678 TMSB4X/ETS1/TNF/TGFB1/SP100 5 GO:0000075 cell cycle checkpoint signaling 3/376 169/18722 0.663066606603981 0.750184846887716 ATM/DUSP1/TAOK3 3 GO:0021543 pallium development 3/376 169/18722 0.663066606603981 0.750184846887716 FLNA/SUN2/BTG2 3 GO:0062012 regulation of small molecule metabolic process 6/376 334/18722 0.664949560300003 0.750621659739623 TMSB4X/PLEK/RORA/TNF/DDIT4/STAT3 6 GO:0021700 developmental maturation 5/376 280/18722 0.665688078004888 0.750621659739623 KLF2/NR4A2/PFN1/SEMA4D/YWHAZ 5 GO:0044106 cellular amine metabolic process 2/376 113/18722 0.665945616769426 0.750621659739623 ITGB2/NR4A2 2 GO:0007215 glutamate receptor signaling pathway 1/376 54/18722 0.666164616217952 0.750621659739623 FYN 1 GO:0010659 cardiac muscle cell apoptotic process 1/376 54/18722 0.666164616217952 0.750621659739623 CFLAR 1 GO:0014888 striated muscle adaptation 1/376 54/18722 0.666164616217952 0.750621659739623 CFLAR 1 GO:0030834 regulation of actin filament depolymerization 1/376 54/18722 0.666164616217952 0.750621659739623 PLEK 1 GO:0035065 regulation of histone acetylation 1/376 54/18722 0.666164616217952 0.750621659739623 KMT2A 1 GO:0043647 inositol phosphate metabolic process 1/376 54/18722 0.666164616217952 0.750621659739623 PLEK 1 GO:0070839 metal ion export 1/376 54/18722 0.666164616217952 0.750621659739623 CALM1 1 GO:0072348 sulfur compound transport 1/376 54/18722 0.666164616217952 0.750621659739623 SLC9A3R1 1 GO:0072698 protein localization to microtubule cytoskeleton 1/376 54/18722 0.666164616217952 0.750621659739623 ABHD17A 1 GO:0086002 cardiac muscle cell action potential involved in contraction 1/376 54/18722 0.666164616217952 0.750621659739623 FLNA 1 GO:2000179 positive regulation of neural precursor cell proliferation 1/376 54/18722 0.666164616217952 0.750621659739623 FLNA 1 GO:0006753 nucleoside phosphate metabolic process 9/376 497/18722 0.670370051867926 0.754782026286095 TMSB4X/GIMAP7/RORA/DDIT4/TGFB1/SAMHD1/STAT3/GUK1/APRT 9 GO:0021987 cerebral cortex development 2/376 114/18722 0.67065588487292 0.754782026286095 FLNA/SUN2 2 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/376 114/18722 0.67065588487292 0.754782026286095 TGFB1/ZEB2 2 GO:1903008 organelle disassembly 2/376 114/18722 0.67065588487292 0.754782026286095 TOMM7/VPS13C 2 GO:0051048 negative regulation of secretion 3/376 171/18722 0.670830786717241 0.754782026286095 HLA-F/UCP2/RAP1B 3 GO:0007411 axon guidance 4/376 227/18722 0.671728112024999 0.755397197609215 RAC2/FYN/SEMA4D/EMB 4 GO:1903532 positive regulation of secretion by cell 5/376 282/18722 0.671767417538414 0.755397197609215 HLA-F/ITGB2/TGFB1/RAB27A/RAB8B 5 GO:0001755 neural crest cell migration 1/376 55/18722 0.672888534382835 0.755561596851199 SEMA4D 1 GO:0008333 endosome to lysosome transport 1/376 55/18722 0.672888534382835 0.755561596851199 LYST 1 GO:0043331 response to dsRNA 1/376 55/18722 0.672888534382835 0.755561596851199 NFKBIA 1 GO:0051898 negative regulation of protein kinase B signaling 1/376 55/18722 0.672888534382835 0.755561596851199 SLC9A3R1 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/376 55/18722 0.672888534382835 0.755561596851199 CCL5 1 GO:0060271 cilium assembly 6/376 337/18722 0.673319773272667 0.755826802268709 FLNA/CYLD/OFD1/ACTR3/ODF2L/ACTR2 6 GO:0097485 neuron projection guidance 4/376 228/18722 0.675070105806198 0.757186131479773 RAC2/FYN/SEMA4D/EMB 4 GO:0000077 DNA damage checkpoint signaling 2/376 115/18722 0.675312327843637 0.757186131479773 ATM/TAOK3 2 GO:0043279 response to alkaloid 2/376 115/18722 0.675312327843637 0.757186131479773 CXCR4/FOSB 2 GO:1901989 positive regulation of cell cycle phase transition 2/376 115/18722 0.675312327843637 0.757186131479773 CCND2/KMT2E 2 GO:0010658 striated muscle cell apoptotic process 1/376 56/18722 0.679477376246662 0.759658059133241 CFLAR 1 GO:0015800 acidic amino acid transport 1/376 56/18722 0.679477376246662 0.759658059133241 SLC9A3R1 1 GO:0030166 proteoglycan biosynthetic process 1/376 56/18722 0.679477376246662 0.759658059133241 CHST12 1 GO:0046456 icosanoid biosynthetic process 1/376 56/18722 0.679477376246662 0.759658059133241 ALOX5AP 1 GO:0046622 positive regulation of organ growth 1/376 56/18722 0.679477376246662 0.759658059133241 PIM1 1 GO:0051058 negative regulation of small GTPase mediated signal transduction 1/376 56/18722 0.679477376246662 0.759658059133241 RASA2 1 GO:0055078 sodium ion homeostasis 1/376 56/18722 0.679477376246662 0.759658059133241 MLLT6 1 GO:0070534 protein K63-linked ubiquitination 1/376 56/18722 0.679477376246662 0.759658059133241 PTPN22 1 GO:0090175 regulation of establishment of planar polarity 1/376 56/18722 0.679477376246662 0.759658059133241 CDC42 1 GO:1990089 response to nerve growth factor 1/376 56/18722 0.679477376246662 0.759658059133241 CORO1A 1 GO:0021782 glial cell development 2/376 116/18722 0.679915201473909 0.759709171197058 TNF/VIM 2 GO:1990748 cellular detoxification 2/376 116/18722 0.679915201473909 0.759709171197058 ALOX5AP/PIM1 2 GO:0030301 cholesterol transport 2/376 117/18722 0.684464772989009 0.76435187185372 PIP4K2A/NFKBIA 2 GO:0051225 spindle assembly 2/376 117/18722 0.684464772989009 0.76435187185372 FLNA/KIF2A 2 GO:0050879 multicellular organismal movement 1/376 57/18722 0.685933848256265 0.764890262444037 RCSD1 1 GO:0050881 musculoskeletal movement 1/376 57/18722 0.685933848256265 0.764890262444037 RCSD1 1 GO:0050891 multicellular organismal water homeostasis 1/376 57/18722 0.685933848256265 0.764890262444037 PRKACB 1 GO:0051205 protein insertion into membrane 1/376 57/18722 0.685933848256265 0.764890262444037 GZMB 1 GO:0061005 cell differentiation involved in kidney development 1/376 57/18722 0.685933848256265 0.764890262444037 STAT1 1 GO:0009308 amine metabolic process 2/376 118/18722 0.688961320487429 0.768045200485842 ITGB2/NR4A2 2 GO:0006826 iron ion transport 1/376 58/18722 0.692260602773042 0.769730225465004 B2M 1 GO:0007131 reciprocal meiotic recombination 1/376 58/18722 0.692260602773042 0.769730225465004 ATM 1 GO:0010043 response to zinc ion 1/376 58/18722 0.692260602773042 0.769730225465004 CRIP1 1 GO:0010559 regulation of glycoprotein biosynthetic process 1/376 58/18722 0.692260602773042 0.769730225465004 ITM2A 1 GO:0018208 peptidyl-proline modification 1/376 58/18722 0.692260602773042 0.769730225465004 FKBP11 1 GO:0032387 negative regulation of intracellular transport 1/376 58/18722 0.692260602773042 0.769730225465004 SP100 1 GO:0035904 aorta development 1/376 58/18722 0.692260602773042 0.769730225465004 PRDM1 1 GO:0044380 protein localization to cytoskeleton 1/376 58/18722 0.692260602773042 0.769730225465004 ABHD17A 1 GO:0140527 reciprocal homologous recombination 1/376 58/18722 0.692260602773042 0.769730225465004 ATM 1 GO:0098739 import across plasma membrane 3/376 177/18722 0.693334514158583 0.770703167631816 FYN/SLC2A3/SLC9A3R1 3 GO:0060560 developmental growth involved in morphogenesis 4/376 234/18722 0.69462645377259 0.771917840082818 CXCR4/ITGA4/SEMA4D/MACF1 4 GO:0035265 organ growth 3/376 178/18722 0.696970421325966 0.774300568416892 STK4/AKAP13/PIM1 3 GO:0048675 axon extension 2/376 120/18722 0.69779650695979 0.774996120512808 SEMA4D/MACF1 2 GO:0006767 water-soluble vitamin metabolic process 1/376 59/18722 0.698460239150954 0.775066846136869 SLC2A3 1 GO:0048010 vascular endothelial growth factor receptor signaling pathway 1/376 59/18722 0.698460239150954 0.775066846136869 FYN 1 GO:2001258 negative regulation of cation channel activity 1/376 59/18722 0.698460239150954 0.775066846136869 CALM1 1 GO:0006936 muscle contraction 6/376 347/18722 0.700246063143736 0.776826079210414 CALM1/CXCR4/TPM3/RCSD1/FLNA/ROCK1 6 GO:0007626 locomotory behavior 3/376 179/18722 0.700573680744186 0.776946394965532 CCND2/NR4A2/ID2 3 GO:0030072 peptide hormone secretion 4/376 236/18722 0.700956024980516 0.776946394965532 CCL5/TNF/RAB8B/UCP2 4 GO:0090068 positive regulation of cell cycle process 4/376 236/18722 0.700956024980516 0.776946394965532 CCND2/KMT2E/CDC42/ATRX 4 GO:0038127 ERBB signaling pathway 2/376 121/18722 0.70213575170508 0.77736458224491 TGFB1/CBLB 2 GO:0042752 regulation of circadian rhythm 2/376 121/18722 0.70213575170508 0.77736458224491 RORA/ID2 2 GO:0043244 regulation of protein-containing complex disassembly 2/376 121/18722 0.70213575170508 0.77736458224491 PLEK/TNF 2 GO:0045931 positive regulation of mitotic cell cycle 2/376 121/18722 0.70213575170508 0.77736458224491 CCND2/KMT2E 2 GO:1901617 organic hydroxy compound biosynthetic process 4/376 237/18722 0.704085306544497 0.778686339439029 PLEK/TNF/NR4A2/ZEB2 4 GO:0031102 neuron projection regeneration 1/376 60/18722 0.704535304793093 0.778686339439029 FLNA 1 GO:0035825 homologous recombination 1/376 60/18722 0.704535304793093 0.778686339439029 ATM 1 GO:0051965 positive regulation of synapse assembly 1/376 60/18722 0.704535304793093 0.778686339439029 SEMA4D 1 GO:0055008 cardiac muscle tissue morphogenesis 1/376 60/18722 0.704535304793093 0.778686339439029 TGFB1 1 GO:0060038 cardiac muscle cell proliferation 1/376 60/18722 0.704535304793093 0.778686339439029 PIM1 1 GO:0019748 secondary metabolic process 1/376 61/18722 0.710488296187252 0.783666508570289 ZEB2 1 GO:0043954 cellular component maintenance 1/376 61/18722 0.710488296187252 0.783666508570289 FYN 1 GO:0043966 histone H3 acetylation 1/376 61/18722 0.710488296187252 0.783666508570289 KMT2A 1 GO:0060998 regulation of dendritic spine development 1/376 61/18722 0.710488296187252 0.783666508570289 ACTR2 1 GO:0090342 regulation of cell aging 1/376 61/18722 0.710488296187252 0.783666508570289 B2M 1 GO:1904356 regulation of telomere maintenance via telomere lengthening 1/376 61/18722 0.710488296187252 0.783666508570289 ATM 1 GO:0003231 cardiac ventricle development 2/376 123/18722 0.710659125449289 0.783666508570289 PRDM1/TGFB1 2 GO:0031570 DNA integrity checkpoint signaling 2/376 123/18722 0.710659125449289 0.783666508570289 ATM/TAOK3 2 GO:0097237 cellular response to toxic substance 2/376 124/18722 0.71484391166712 0.787669248636063 ALOX5AP/PIM1 2 GO:0016570 histone modification 8/376 463/18722 0.71558100147997 0.787669248636063 HOPX/ATM/KMT2A/KMT2E/EPC1/MLLT6/PRMT2/ATRX 8 GO:0007062 sister chromatid cohesion 1/376 62/18722 0.716321659920899 0.787669248636063 ATRX 1 GO:0019933 cAMP-mediated signaling 1/376 62/18722 0.716321659920899 0.787669248636063 SLC9A3R1 1 GO:0031124 mRNA 3'-end processing 1/376 62/18722 0.716321659920899 0.787669248636063 PABPC1 1 GO:0032835 glomerulus development 1/376 62/18722 0.716321659920899 0.787669248636063 CFLAR 1 GO:0046173 polyol biosynthetic process 1/376 62/18722 0.716321659920899 0.787669248636063 PLEK 1 GO:0060113 inner ear receptor cell differentiation 1/376 62/18722 0.716321659920899 0.787669248636063 SLC9A3R1 1 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1/376 62/18722 0.716321659920899 0.787669248636063 TGFB1 1 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 1/376 62/18722 0.716321659920899 0.787669248636063 VAMP2 1 GO:0055001 muscle cell development 3/376 184/18722 0.718102660706392 0.789179753328777 AKAP13/ACTG1/CFLAR 3 GO:2001257 regulation of cation channel activity 3/376 184/18722 0.718102660706392 0.789179753328777 TMSB4X/CALM1/VAMP2 3 GO:0055007 cardiac muscle cell differentiation 2/376 125/18722 0.718977881601901 0.789693676646079 TGFB1/AKAP13 2 GO:2000027 regulation of animal organ morphogenesis 2/376 125/18722 0.718977881601901 0.789693676646079 TNF/CDC42 2 GO:0002790 peptide secretion 4/376 242/18722 0.719377011858904 0.789908166889559 CCL5/TNF/RAB8B/UCP2 4 GO:0016239 positive regulation of macroautophagy 1/376 63/18722 0.722037793675977 0.792156412937262 PIP4K2A 1 GO:0045143 homologous chromosome segregation 1/376 63/18722 0.722037793675977 0.792156412937262 CENPC 1 GO:2000756 regulation of peptidyl-lysine acetylation 1/376 63/18722 0.722037793675977 0.792156412937262 KMT2A 1 GO:0031929 TOR signaling 2/376 126/18722 0.723061382220795 0.793054870111967 DDIT4/ATM 2 GO:0008217 regulation of blood pressure 3/376 186/18722 0.724888361832872 0.794833730079904 CYBA/ID2/LNPEP 3 GO:0030198 extracellular matrix organization 5/376 301/18722 0.725844655078149 0.795657153727815 ETS1/LCP1/TNF/TGFB1/CFLAR 5 GO:0006749 glutathione metabolic process 1/376 64/18722 0.727639047203917 0.79582311823742 CLIC1 1 GO:0030104 water homeostasis 1/376 64/18722 0.727639047203917 0.79582311823742 PRKACB 1 GO:0045995 regulation of embryonic development 1/376 64/18722 0.727639047203917 0.79582311823742 CFL1 1 GO:0046888 negative regulation of hormone secretion 1/376 64/18722 0.727639047203917 0.79582311823742 UCP2 1 GO:0050771 negative regulation of axonogenesis 1/376 64/18722 0.727639047203917 0.79582311823742 SEMA4D 1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 1/376 64/18722 0.727639047203917 0.79582311823742 UCP2 1 GO:0070542 response to fatty acid 1/376 64/18722 0.727639047203917 0.79582311823742 UCP2 1 GO:1903018 regulation of glycoprotein metabolic process 1/376 64/18722 0.727639047203917 0.79582311823742 ITM2A 1 GO:0043062 extracellular structure organization 5/376 302/18722 0.728505125944347 0.796545531330233 ETS1/LCP1/TNF/TGFB1/CFLAR 5 GO:0006639 acylglycerol metabolic process 2/376 128/18722 0.73107839587439 0.798908286523762 DGKZ/SORL1 2 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 2/376 128/18722 0.73107839587439 0.798908286523762 TGFB1/ZEB2 2 GO:0006487 protein N-linked glycosylation 1/376 65/18722 0.733127723281274 0.799119529596325 MGAT4A 1 GO:0035418 protein localization to synapse 1/376 65/18722 0.733127723281274 0.799119529596325 VAMP2 1 GO:0046503 glycerolipid catabolic process 1/376 65/18722 0.733127723281274 0.799119529596325 SORL1 1 GO:0048645 animal organ formation 1/376 65/18722 0.733127723281274 0.799119529596325 PIM1 1 GO:0051310 metaphase plate congression 1/376 65/18722 0.733127723281274 0.799119529596325 CENPC 1 GO:0060389 pathway-restricted SMAD protein phosphorylation 1/376 65/18722 0.733127723281274 0.799119529596325 TGFB1 1 GO:0061512 protein localization to cilium 1/376 65/18722 0.733127723281274 0.799119529596325 RAB29 1 GO:0070936 protein K48-linked ubiquitination 1/376 65/18722 0.733127723281274 0.799119529596325 TNFAIP3 1 GO:1905330 regulation of morphogenesis of an epithelium 1/376 65/18722 0.733127723281274 0.799119529596325 TNF 1 GO:0045229 external encapsulating structure organization 5/376 304/18722 0.733770298915957 0.799595024831084 ETS1/LCP1/TNF/TGFB1/CFLAR 5 GO:0006334 nucleosome assembly 2/376 129/18722 0.735012634144231 0.800498582717508 ATRX/HP1BP3 2 GO:0006638 neutral lipid metabolic process 2/376 129/18722 0.735012634144231 0.800498582717508 DGKZ/SORL1 2 GO:0051216 cartilage development 3/376 190/18722 0.738076823452193 0.802543340749116 RUNX3/TGFB1/CD44 3 GO:0006303 double-strand break repair via nonhomologous end joining 1/376 66/18722 0.73850607864635 0.802543340749116 ATM 1 GO:0071300 cellular response to retinoic acid 1/376 66/18722 0.73850607864635 0.802543340749116 ATM 1 GO:2000573 positive regulation of DNA biosynthetic process 1/376 66/18722 0.73850607864635 0.802543340749116 ATM 1 GO:0006352 DNA-templated transcription, initiation 2/376 130/18722 0.738897852803442 0.802543340749116 JUN/ATF7IP 2 GO:0015918 sterol transport 2/376 130/18722 0.738897852803442 0.802543340749116 PIP4K2A/NFKBIA 2 GO:0030534 adult behavior 2/376 130/18722 0.738897852803442 0.802543340749116 CCND2/NR4A2 2 GO:0043467 regulation of generation of precursor metabolites and energy 2/376 130/18722 0.738897852803442 0.802543340749116 DDIT4/STAT3 2 GO:0051028 mRNA transport 2/376 130/18722 0.738897852803442 0.802543340749116 ZFP36/SRSF7 2 GO:0006650 glycerophospholipid metabolic process 5/376 306/18722 0.738961197365896 0.802543340749116 PLEK/PIP4K2A/ATM/DGKZ/PIK3R1 5 GO:0046883 regulation of hormone secretion 4/376 249/18722 0.739796347585527 0.803225230286892 CCL5/TNF/RAB8B/UCP2 4 GO:0042490 mechanoreceptor differentiation 1/376 67/18722 0.7437763249172 0.807094163834822 SLC9A3R1 1 GO:0061077 chaperone-mediated protein folding 1/376 67/18722 0.7437763249172 0.807094163834822 FKBP11 1 GO:0045017 glycerolipid biosynthetic process 4/376 252/18722 0.748197002168789 0.811561783914725 PIP4K2A/ATM/DGKZ/PIK3R1 4 GO:0042698 ovulation cycle 1/376 68/18722 0.74894062949137 0.811561783914725 ETS1 1 GO:0051926 negative regulation of calcium ion transport 1/376 68/18722 0.74894062949137 0.811561783914725 CALM1 1 GO:1901016 regulation of potassium ion transmembrane transporter activity 1/376 68/18722 0.74894062949137 0.811561783914725 VAMP2 1 GO:1901607 alpha-amino acid biosynthetic process 1/376 68/18722 0.74894062949137 0.811561783914725 GLS 1 GO:0008654 phospholipid biosynthetic process 4/376 253/18722 0.750950851464032 0.813512594191536 PIP4K2A/ATM/DGKZ/PIK3R1 4 GO:0030073 insulin secretion 3/376 195/18722 0.753854040980163 0.815221631182347 CCL5/TNF/UCP2 3 GO:0001508 action potential 2/376 134/18722 0.753956119220989 0.815221631182347 CALM1/FLNA 2 GO:0010611 regulation of cardiac muscle hypertrophy 1/376 69/18722 0.75400111642775 0.815221631182347 ROCK1 1 GO:0033344 cholesterol efflux 1/376 69/18722 0.75400111642775 0.815221631182347 NFKBIA 1 GO:0034605 cellular response to heat 1/376 69/18722 0.75400111642775 0.815221631182347 ATM 1 GO:0050805 negative regulation of synaptic transmission 1/376 69/18722 0.75400111642775 0.815221631182347 RAP1B 1 GO:0070192 chromosome organization involved in meiotic cell cycle 1/376 69/18722 0.75400111642775 0.815221631182347 ATRX 1 GO:0006338 chromatin remodeling 4/376 255/18722 0.756389351471756 0.817517666443419 ACTB/ANP32E/ATRX/HP1BP3 4 GO:0045787 positive regulation of cell cycle 5/376 313/18722 0.756546671449316 0.817517666443419 CCND2/RPS15A/KMT2E/CDC42/ATRX 5 GO:0001763 morphogenesis of a branching structure 3/376 196/18722 0.756916335583165 0.817689099633333 PRDM1/TNF/STK4 3 GO:0009581 detection of external stimulus 2/376 135/18722 0.757601968349152 0.817973705030082 FYN/CXCR4 2 GO:0042157 lipoprotein metabolic process 2/376 135/18722 0.757601968349152 0.817973705030082 ABHD17A/APOL6 2 GO:0060415 muscle tissue morphogenesis 1/376 70/18722 0.758959867310888 0.81887868990511 TGFB1 1 GO:0034976 response to endoplasmic reticulum stress 4/376 256/18722 0.759074130100427 0.81887868990511 JUN/PIK3R1/XBP1/PPP1R15A 4 GO:1903522 regulation of blood circulation 4/376 256/18722 0.759074130100427 0.81887868990511 HOPX/CELF2/CALM1/FLNA 4 GO:0003208 cardiac ventricle morphogenesis 1/376 71/18722 0.763818922098102 0.823309686545242 TGFB1 1 GO:0003281 ventricular septum development 1/376 71/18722 0.763818922098102 0.823309686545242 PRDM1 1 GO:0033555 multicellular organismal response to stress 1/376 71/18722 0.763818922098102 0.823309686545242 NR4A2 1 GO:0009582 detection of abiotic stimulus 2/376 138/18722 0.768260916266324 0.825685773441997 FYN/CXCR4 2 GO:0035107 appendage morphogenesis 2/376 138/18722 0.768260916266324 0.825685773441997 MBNL1/ATRX 2 GO:0035108 limb morphogenesis 2/376 138/18722 0.768260916266324 0.825685773441997 MBNL1/ATRX 2 GO:0055076 transition metal ion homeostasis 2/376 138/18722 0.768260916266324 0.825685773441997 B2M/LCK 2 GO:0000271 polysaccharide biosynthetic process 1/376 72/18722 0.768580279949751 0.825685773441997 TGFB1 1 GO:0001707 mesoderm formation 1/376 72/18722 0.768580279949751 0.825685773441997 EOMES 1 GO:0001736 establishment of planar polarity 1/376 72/18722 0.768580279949751 0.825685773441997 CDC42 1 GO:0005977 glycogen metabolic process 1/376 72/18722 0.768580279949751 0.825685773441997 PPP1R2 1 GO:0007164 establishment of tissue polarity 1/376 72/18722 0.768580279949751 0.825685773441997 CDC42 1 GO:0014743 regulation of muscle hypertrophy 1/376 72/18722 0.768580279949751 0.825685773441997 ROCK1 1 GO:0050709 negative regulation of protein secretion 1/376 72/18722 0.768580279949751 0.825685773441997 UCP2 1 GO:0055021 regulation of cardiac muscle tissue growth 1/376 72/18722 0.768580279949751 0.825685773441997 PIM1 1 GO:0006260 DNA replication 4/376 260/18722 0.769585049462541 0.826536049519774 JUN/SAMHD1/CDC42/ATRX 4 GO:0016579 protein deubiquitination 2/376 139/18722 0.771722372591249 0.82702949562975 TNFAIP3/CYLD 2 GO:0006403 RNA localization 3/376 201/18722 0.771769993298711 0.82702949562975 ATM/ZFP36/SRSF7 3 GO:0006473 protein acetylation 3/376 201/18722 0.771769993298711 0.82702949562975 KMT2A/TERF2IP/EPC1 3 GO:0090305 nucleic acid phosphodiester bond hydrolysis 4/376 261/18722 0.772156101220964 0.82702949562975 ISG20/ZFP36/SAMHD1/CNOT6L 4 GO:0006073 cellular glucan metabolic process 1/376 73/18722 0.773245900042989 0.82702949562975 PPP1R2 1 GO:0009166 nucleotide catabolic process 1/376 73/18722 0.773245900042989 0.82702949562975 SAMHD1 1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 1/376 73/18722 0.773245900042989 0.82702949562975 UCP2 1 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1/376 73/18722 0.773245900042989 0.82702949562975 CBLB 1 GO:0042274 ribosomal small subunit biogenesis 1/376 73/18722 0.773245900042989 0.82702949562975 RPS27 1 GO:0044042 glucan metabolic process 1/376 73/18722 0.773245900042989 0.82702949562975 PPP1R2 1 GO:0051145 smooth muscle cell differentiation 1/376 73/18722 0.773245900042989 0.82702949562975 EPC1 1 GO:0051865 protein autoubiquitination 1/376 73/18722 0.773245900042989 0.82702949562975 RNF213 1 GO:0051937 catecholamine transport 1/376 73/18722 0.773245900042989 0.82702949562975 ACTB 1 GO:0072088 nephron epithelium morphogenesis 1/376 73/18722 0.773245900042989 0.82702949562975 STAT1 1 GO:0086003 cardiac muscle cell contraction 1/376 73/18722 0.773245900042989 0.82702949562975 FLNA 1 GO:0016051 carbohydrate biosynthetic process 3/376 202/18722 0.774650241682836 0.82830289363162 PLEK/TGFB1/CHST12 3 GO:0048332 mesoderm morphogenesis 1/376 74/18722 0.777817702369325 0.831001818770646 EOMES 1 GO:0048844 artery morphogenesis 1/376 74/18722 0.777817702369325 0.831001818770646 PRDM1 1 GO:0070972 protein localization to endoplasmic reticulum 1/376 74/18722 0.777817702369325 0.831001818770646 PPP1R15A 1 GO:0016241 regulation of macroautophagy 2/376 141/18722 0.77851043386759 0.831054526511546 PIP4K2A/VPS13C 2 GO:0035296 regulation of tube diameter 2/376 141/18722 0.77851043386759 0.831054526511546 KLF2/ROCK1 2 GO:0097746 blood vessel diameter maintenance 2/376 141/18722 0.77851043386759 0.831054526511546 KLF2/ROCK1 2 GO:0035150 regulation of tube size 2/376 142/18722 0.781837858669137 0.834146944477672 KLF2/ROCK1 2 GO:0072006 nephron development 2/376 142/18722 0.781837858669137 0.834146944477672 STAT1/CFLAR 2 GO:0031023 microtubule organizing center organization 2/376 143/18722 0.785121428901389 0.837419635836191 GCC2/PPP1R12A 2 GO:0008652 cellular amino acid biosynthetic process 1/376 76/18722 0.786687342433724 0.838397539034841 GLS 1 GO:0072028 nephron morphogenesis 1/376 76/18722 0.786687342433724 0.838397539034841 STAT1 1 GO:0140115 export across plasma membrane 1/376 76/18722 0.786687342433724 0.838397539034841 CALM1 1 GO:0031644 regulation of nervous system process 2/376 144/18722 0.788361558276283 0.839950794149188 CST7/CCL3 2 GO:0006367 transcription initiation from RNA polymerase II promoter 1/376 77/18722 0.79098883118439 0.841824147442876 ATF7IP 1 GO:0021675 nerve development 1/376 77/18722 0.79098883118439 0.841824147442876 ITGA4 1 GO:0048644 muscle organ morphogenesis 1/376 77/18722 0.79098883118439 0.841824147442876 TGFB1 1 GO:0055117 regulation of cardiac muscle contraction 1/376 77/18722 0.79098883118439 0.841824147442876 CALM1 1 GO:0006836 neurotransmitter transport 3/376 208/18722 0.791312103626762 0.841936958142148 CALM1/VAMP2/RAP1B 3 GO:0009064 glutamine family amino acid metabolic process 1/376 78/18722 0.795203805680216 0.845149409492824 GLS 1 GO:0032371 regulation of sterol transport 1/376 78/18722 0.795203805680216 0.845149409492824 NFKBIA 1 GO:0032374 regulation of cholesterol transport 1/376 78/18722 0.795203805680216 0.845149409492824 NFKBIA 1 GO:0061045 negative regulation of wound healing 1/376 78/18722 0.795203805680216 0.845149409492824 TNF 1 GO:0006029 proteoglycan metabolic process 1/376 79/18722 0.799334001403464 0.848840574250048 CHST12 1 GO:0060420 regulation of heart growth 1/376 79/18722 0.799334001403464 0.848840574250048 PIM1 1 GO:1901184 regulation of ERBB signaling pathway 1/376 79/18722 0.799334001403464 0.848840574250048 CBLB 1 GO:0070507 regulation of microtubule cytoskeleton organization 2/376 148/18722 0.800895975984613 0.850266275874076 CYLD/ROCK1 2 GO:0006457 protein folding 3/376 212/18722 0.801842633500666 0.851038127859512 B2M/FKBP11/DNAJC1 3 GO:0046486 glycerolipid metabolic process 6/376 392/18722 0.802514707416468 0.851518206801428 PLEK/PIP4K2A/ATM/DGKZ/PIK3R1/SORL1 6 GO:0007422 peripheral nervous system development 1/376 80/18722 0.80338111911372 0.851737848581577 RUNX3 1 GO:0021766 hippocampus development 1/376 80/18722 0.80338111911372 0.851737848581577 BTG2 1 GO:1901264 carbohydrate derivative transport 1/376 80/18722 0.80338111911372 0.851737848581577 GUK1 1 GO:0001505 regulation of neurotransmitter levels 3/376 213/18722 0.804404745499451 0.852589821884675 CALM1/VAMP2/RAP1B 3 GO:0001942 hair follicle development 1/376 81/18722 0.807346825540779 0.855240281293198 TNF 1 GO:0014032 neural crest cell development 1/376 81/18722 0.807346825540779 0.855240281293198 SEMA4D 1 GO:0034470 ncRNA processing 6/376 395/18722 0.808249686185142 0.855962704008588 ISG20/RPS27/RPL35A/LYAR/STAT3/DDX17 6 GO:0006261 DNA-dependent DNA replication 2/376 151/18722 0.809861053704006 0.856732618919745 SAMHD1/ATRX 2 GO:0031497 chromatin assembly 2/376 151/18722 0.809861053704006 0.856732618919745 ATRX/HP1BP3 2 GO:0048592 eye morphogenesis 2/376 151/18722 0.809861053704006 0.856732618919745 PRDM1/STAT3 2 GO:0048754 branching morphogenesis of an epithelial tube 2/376 151/18722 0.809861053704006 0.856732618919745 TNF/STK4 2 GO:0007032 endosome organization 1/376 82/18722 0.811232754063748 0.857247592581681 RAB27A 1 GO:0016575 histone deacetylation 1/376 82/18722 0.811232754063748 0.857247592581681 HOPX 1 GO:0043242 negative regulation of protein-containing complex disassembly 1/376 82/18722 0.811232754063748 0.857247592581681 TNF 1 GO:0046889 positive regulation of lipid biosynthetic process 1/376 82/18722 0.811232754063748 0.857247592581681 TNF 1 GO:0016573 histone acetylation 2/376 152/18722 0.8127686409573 0.858402421289053 KMT2A/EPC1 2 GO:0098754 detoxification 2/376 152/18722 0.8127686409573 0.858402421289053 ALOX5AP/PIM1 2 GO:0051899 membrane depolarization 1/376 83/18722 0.815040505376626 0.860332867974509 JUN 1 GO:1901292 nucleoside phosphate catabolic process 1/376 83/18722 0.815040505376626 0.860332867974509 SAMHD1 1 GO:0016052 carbohydrate catabolic process 2/376 154/18722 0.818465158413393 0.861923427477578 DDIT4/STAT3 2 GO:0050770 regulation of axonogenesis 2/376 154/18722 0.818465158413393 0.861923427477578 SEMA4D/MACF1 2 GO:0002088 lens development in camera-type eye 1/376 84/18722 0.818771648140636 0.861923427477578 VIM 1 GO:0006112 energy reserve metabolic process 1/376 84/18722 0.818771648140636 0.861923427477578 PPP1R2 1 GO:0009953 dorsal/ventral pattern formation 1/376 84/18722 0.818771648140636 0.861923427477578 PRKACB 1 GO:0015844 monoamine transport 1/376 84/18722 0.818771648140636 0.861923427477578 ACTB 1 GO:0022404 molting cycle process 1/376 84/18722 0.818771648140636 0.861923427477578 TNF 1 GO:0022405 hair cycle process 1/376 84/18722 0.818771648140636 0.861923427477578 TNF 1 GO:0032370 positive regulation of lipid transport 1/376 84/18722 0.818771648140636 0.861923427477578 NFKBIA 1 GO:0098586 cellular response to virus 1/376 84/18722 0.818771648140636 0.861923427477578 CCL5 1 GO:0031503 protein-containing complex localization 3/376 220/18722 0.82157076566947 0.864597779039982 TYROBP/ATM/VAMP2 3 GO:0001656 metanephros development 1/376 85/18722 0.82242771962358 0.864597779039982 STAT1 1 GO:0055013 cardiac muscle cell development 1/376 85/18722 0.82242771962358 0.864597779039982 AKAP13 1 GO:0055072 iron ion homeostasis 1/376 85/18722 0.82242771962358 0.864597779039982 B2M 1 GO:0098773 skin epidermis development 1/376 85/18722 0.82242771962358 0.864597779039982 TNF 1 GO:0008406 gonad development 3/376 221/18722 0.823915542356207 0.865787465378391 FLNA/ATRX/SF1 3 GO:0035051 cardiocyte differentiation 2/376 156/18722 0.824006238016905 0.865787465378391 TGFB1/AKAP13 2 GO:0023061 signal release 7/376 463/18722 0.82519522541111 0.866638036958244 CCL5/TNF/CALM1/RAB8B/UCP2/VAMP2/RAP1B 7 GO:0015850 organic hydroxy compound transport 4/376 284/18722 0.825263059709915 0.866638036958244 PIP4K2A/ACTB/EMB/NFKBIA 4 GO:0014031 mesenchymal cell development 1/376 86/18722 0.826010226326458 0.867187652943654 SEMA4D 1 GO:0070646 protein modification by small protein removal 2/376 157/18722 0.826719524939927 0.8676972262032 TNFAIP3/CYLD 2 GO:0018393 internal peptidyl-lysine acetylation 2/376 158/18722 0.82939519399578 0.869930310640258 KMT2A/EPC1 2 GO:1901606 alpha-amino acid catabolic process 1/376 87/18722 0.829520644597614 0.869930310640258 GLS 1 GO:1901879 regulation of protein depolymerization 1/376 87/18722 0.829520644597614 0.869930310640258 PLEK 1 GO:0006475 internal protein amino acid acetylation 2/376 160/18722 0.834635323506379 0.874584066681239 KMT2A/EPC1 2 GO:0035637 multicellular organismal signaling 2/376 160/18722 0.834635323506379 0.874584066681239 CALM1/FLNA 2 GO:0043271 negative regulation of ion transport 2/376 160/18722 0.834635323506379 0.874584066681239 CALM1/SLC9A3R1 2 GO:0003205 cardiac chamber development 2/376 161/18722 0.837200603068514 0.877034965366448 PRDM1/TGFB1 2 GO:0045137 development of primary sexual characteristics 3/376 227/18722 0.837439036913173 0.877047640010418 FLNA/ATRX/SF1 3 GO:0016236 macroautophagy 4/376 291/18722 0.83924582818785 0.878702400493898 CALM1/PIP4K2A/TOMM7/VPS13C 4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1/376 90/18722 0.839633692571047 0.87887103152696 RNF19A 1 GO:0071695 anatomical structure maturation 3/376 229/18722 0.841743983637574 0.88035606769707 KLF2/NR4A2/SEMA4D 3 GO:0050657 nucleic acid transport 2/376 163/18722 0.842223628243509 0.88035606769707 ZFP36/SRSF7 2 GO:0050658 RNA transport 2/376 163/18722 0.842223628243509 0.88035606769707 ZFP36/SRSF7 2 GO:0002065 columnar/cuboidal epithelial cell differentiation 1/376 91/18722 0.842869938362872 0.88035606769707 PRDM1 1 GO:0014033 neural crest cell differentiation 1/376 91/18722 0.842869938362872 0.88035606769707 SEMA4D 1 GO:0019935 cyclic-nucleotide-mediated signaling 1/376 91/18722 0.842869938362872 0.88035606769707 SLC9A3R1 1 GO:0055006 cardiac cell development 1/376 91/18722 0.842869938362872 0.88035606769707 AKAP13 1 GO:0072080 nephron tubule development 1/376 91/18722 0.842869938362872 0.88035606769707 STAT1 1 GO:0001708 cell fate specification 1/376 92/18722 0.846041045827611 0.883430086925894 EOMES 1 GO:0046879 hormone secretion 4/376 295/18722 0.846807831575329 0.883992550472629 CCL5/TNF/RAB8B/UCP2 4 GO:0060993 kidney morphogenesis 1/376 93/18722 0.849148322626796 0.885958468007226 STAT1 1 GO:1901019 regulation of calcium ion transmembrane transporter activity 1/376 93/18722 0.849148322626796 0.885958468007226 CALM1 1 GO:0009451 RNA modification 2/376 167/18722 0.851850838944842 0.888178609380602 APOBEC3G/APOBEC3C 2 GO:0055088 lipid homeostasis 2/376 167/18722 0.851850838944842 0.888178609380602 RORA/XBP1 2 GO:0061326 renal tubule development 1/376 94/18722 0.852193050239246 0.888178609380602 STAT1 1 GO:1903035 negative regulation of response to wounding 1/376 94/18722 0.852193050239246 0.888178609380602 TNF 1 GO:0006942 regulation of striated muscle contraction 1/376 95/18722 0.855176484483934 0.891048367135048 CALM1 1 GO:0018394 peptidyl-lysine acetylation 2/376 169/18722 0.856461410488885 0.892147302592589 KMT2A/EPC1 2 GO:0003073 regulation of systemic arterial blood pressure 1/376 96/18722 0.858099856032441 0.892654212651197 CYBA 1 GO:0030510 regulation of BMP signaling pathway 1/376 96/18722 0.858099856032441 0.892654212651197 SORL1 1 GO:0042472 inner ear morphogenesis 1/376 96/18722 0.858099856032441 0.892654212651197 SLC9A3R1 1 GO:0043648 dicarboxylic acid metabolic process 1/376 96/18722 0.858099856032441 0.892654212651197 GLS 1 GO:0044264 cellular polysaccharide metabolic process 1/376 96/18722 0.858099856032441 0.892654212651197 PPP1R2 1 GO:0034660 ncRNA metabolic process 7/376 485/18722 0.858652747643539 0.892989639591711 MYBL1/ISG20/RPS27/RPL35A/LYAR/STAT3/DDX17 7 GO:0046890 regulation of lipid biosynthetic process 2/376 171/18722 0.86094082761428 0.894673354057631 TNF/SF1 2 GO:0048469 cell maturation 2/376 171/18722 0.86094082761428 0.894673354057631 KLF2/NR4A2 2 GO:0070252 actin-mediated cell contraction 1/376 97/18722 0.860964370911202 0.894673354057631 FLNA 1 GO:0090287 regulation of cellular response to growth factor stimulus 4/376 304/18722 0.862732247735187 0.895965111288376 TGFB1/ZEB2/SORL1/CFLAR 4 GO:0007219 Notch signaling pathway 2/376 172/18722 0.863132325274711 0.895965111288376 STAT3/NFKBIA 2 GO:0048736 appendage development 2/376 172/18722 0.863132325274711 0.895965111288376 MBNL1/ATRX 2 GO:0060173 limb development 2/376 172/18722 0.863132325274711 0.895965111288376 MBNL1/ATRX 2 GO:0032886 regulation of microtubule-based process 3/376 240/18722 0.863699407725285 0.89614817740315 CYLD/MACF1/ROCK1 3 GO:0043502 regulation of muscle adaptation 1/376 98/18722 0.863771210993746 0.89614817740315 ROCK1 1 GO:0006694 steroid biosynthetic process 2/376 173/18722 0.86529219594947 0.897245720980519 TNF/SF1 2 GO:0010469 regulation of signaling receptor activity 2/376 173/18722 0.86529219594947 0.897245720980519 TNF/CBLB 2 GO:0009914 hormone transport 4/376 306/18722 0.86607300575235 0.897815114309886 CCL5/TNF/RAB8B/UCP2 4 GO:0000045 autophagosome assembly 1/376 99/18722 0.866521534483134 0.898039835817637 PIP4K2A 1 GO:0043543 protein acylation 3/376 243/18722 0.869204278614126 0.900110594866654 KMT2A/TERF2IP/EPC1 3 GO:0006641 triglyceride metabolic process 1/376 100/18722 0.869216476384779 0.900110594866654 SORL1 1 GO:0060840 artery development 1/376 100/18722 0.869216476384779 0.900110594866654 PRDM1 1 GO:0003341 cilium movement 2/376 175/18722 0.869518582255989 0.900182876367073 OFD1/SLC9A3R1 2 GO:0051963 regulation of synapse assembly 1/376 101/18722 0.871857148969857 0.902121883113003 SEMA4D 1 GO:0098869 cellular oxidant detoxification 1/376 101/18722 0.871857148969857 0.902121883113003 ALOX5AP 1 GO:0006814 sodium ion transport 3/376 245/18722 0.872764597733541 0.902819758733975 FXYD5/SLC9A3R1/MLLT6 3 GO:0006333 chromatin assembly or disassembly 2/376 177/18722 0.873623012605435 0.903466552934631 ATRX/HP1BP3 2 GO:0003007 heart morphogenesis 3/376 246/18722 0.874512482539418 0.904145109349051 TGFB1/FLNA/PIM1 3 GO:0035725 sodium ion transmembrane transport 2/376 178/18722 0.875630428415429 0.905059458551557 FXYD5/SLC9A3R1 2 GO:0018205 peptidyl-lysine modification 5/376 376/18722 0.876720855090027 0.905247094895896 KMT2A/KMT2E/EPC1/MLLT6/ATRX 5 GO:0002027 regulation of heart rate 1/376 103/18722 0.876980024319792 0.905247094895896 CALM1 1 GO:0003279 cardiac septum development 1/376 103/18722 0.876980024319792 0.905247094895896 PRDM1 1 GO:0090277 positive regulation of peptide hormone secretion 1/376 103/18722 0.876980024319792 0.905247094895896 RAB8B 1 GO:1905037 autophagosome organization 1/376 103/18722 0.876980024319792 0.905247094895896 PIP4K2A 1 GO:0007416 synapse assembly 2/376 179/18722 0.877608470761997 0.905654547057986 RAB29/SEMA4D 2 GO:0022600 digestive system process 1/376 104/18722 0.879464341998279 0.907328095112709 EPB41 1 GO:1905952 regulation of lipid localization 2/376 181/18722 0.881477896757117 0.909163388324149 TNF/NFKBIA 2 GO:0000041 transition metal ion transport 1/376 105/18722 0.881898621051274 0.909355283814179 B2M 1 GO:0061138 morphogenesis of a branching epithelium 2/376 182/18722 0.883370004185714 0.910630158611237 TNF/STK4 2 GO:0002793 positive regulation of peptide secretion 1/376 106/18722 0.88428386671302 0.911087472351223 RAB8B 1 GO:0007218 neuropeptide signaling pathway 1/376 106/18722 0.88428386671302 0.911087472351223 SORL1 1 GO:0006644 phospholipid metabolic process 5/376 383/18722 0.886303716985429 0.912767434456931 PLEK/PIP4K2A/ATM/DGKZ/PIK3R1 5 GO:0042303 molting cycle 1/376 107/18722 0.886621064076358 0.912767434456931 TNF 1 GO:0042633 hair cycle 1/376 107/18722 0.886621064076358 0.912767434456931 TNF 1 GO:0098659 inorganic cation import across plasma membrane 1/376 108/18722 0.888911178495229 0.914639090990179 FYN 1 GO:0099587 inorganic ion import across plasma membrane 1/376 108/18722 0.888911178495229 0.914639090990179 FYN 1 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3/376 256/18722 0.890855397612411 0.915975127166903 TGFB1/ZEB2/SORL1 3 GO:0090596 sensory organ morphogenesis 3/376 256/18722 0.890855397612411 0.915975127166903 PRDM1/SLC9A3R1/STAT3 3 GO:0006821 chloride transport 1/376 109/18722 0.891155155979155 0.915975127166903 CLIC1 1 GO:0072009 nephron epithelium development 1/376 109/18722 0.891155155979155 0.915975127166903 STAT1 1 GO:0005996 monosaccharide metabolic process 3/376 257/18722 0.892380429660944 0.916533347596489 RORA/TNF/SLC2A3 3 GO:0061136 regulation of proteasomal protein catabolic process 2/376 187/18722 0.892418701096259 0.916533347596489 PSME1/RNF19A 2 GO:0006939 smooth muscle contraction 1/376 110/18722 0.893353923579855 0.916533347596489 ROCK1 1 GO:0009063 cellular amino acid catabolic process 1/376 110/18722 0.893353923579855 0.916533347596489 GLS 1 GO:0009408 response to heat 1/376 110/18722 0.893353923579855 0.916533347596489 ATM 1 GO:0048259 regulation of receptor-mediated endocytosis 1/376 110/18722 0.893353923579855 0.916533347596489 B2M 1 GO:1905954 positive regulation of lipid localization 1/376 110/18722 0.893353923579855 0.916533347596489 NFKBIA 1 GO:0001578 microtubule bundle formation 1/376 113/18722 0.899687961137211 0.922787413818606 CCSER2 1 GO:0019751 polyol metabolic process 1/376 114/18722 0.901714793670523 0.924376937955893 PLEK 1 GO:1901800 positive regulation of proteasomal protein catabolic process 1/376 114/18722 0.901714793670523 0.924376937955893 RNF19A 1 GO:0042471 ear morphogenesis 1/376 115/18722 0.903700780212864 0.925922930545968 SLC9A3R1 1 GO:0046916 cellular transition metal ion homeostasis 1/376 115/18722 0.903700780212864 0.925922930545968 LCK 1 GO:0030326 embryonic limb morphogenesis 1/376 116/18722 0.905646741767116 0.927181274596453 MBNL1 1 GO:0031123 RNA 3'-end processing 1/376 116/18722 0.905646741767116 0.927181274596453 PABPC1 1 GO:0035113 embryonic appendage morphogenesis 1/376 116/18722 0.905646741767116 0.927181274596453 MBNL1 1 GO:0006006 glucose metabolic process 2/376 196/18722 0.907084584245533 0.928408020061131 RORA/TNF 2 GO:0007613 memory 1/376 118/18722 0.909421791957527 0.930554381789126 CCND2 1 GO:0048167 regulation of synaptic plasticity 2/376 198/18722 0.910079849474967 0.930981894592264 TYROBP/VAMP2 2 GO:0001655 urogenital system development 4/376 338/18722 0.910735502394861 0.931406722560065 CRIP1/PRDM1/STAT1/CFLAR 4 GO:0010906 regulation of glucose metabolic process 1/376 119/18722 0.911252441614804 0.93168950165102 RORA 1 GO:0006323 DNA packaging 2/376 199/18722 0.91154340646877 0.931741150109861 ATRX/HP1BP3 2 GO:0003206 cardiac chamber morphogenesis 1/376 121/18722 0.91480377594201 0.934827170826817 TGFB1 1 GO:0031109 microtubule polymerization or depolymerization 1/376 122/18722 0.916525929602878 0.936340094176418 KIF2A 1 GO:0007548 sex differentiation 3/376 276/18722 0.917943846449131 0.937541487873058 FLNA/ATRX/SF1 3 GO:0006690 icosanoid metabolic process 1/376 123/18722 0.918213362423809 0.937569638838541 ALOX5AP 1 GO:0007368 determination of left/right symmetry 1/376 124/18722 0.919866772592563 0.939010469914695 OFD1 1 GO:0035270 endocrine system development 1/376 127/18722 0.924629640696404 0.943623876138679 ETS1 1 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 1/376 130/18722 0.929110126898674 0.947697220777141 SORL1 1 GO:0007098 centrosome cycle 1/376 130/18722 0.929110126898674 0.947697220777141 PPP1R12A 1 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1/376 131/18722 0.930543786122324 0.948909781901054 SORL1 1 GO:0071103 DNA conformation change 3/376 290/18722 0.933101519825511 0.950995032368934 ATRX/CHD9/HP1BP3 3 GO:0009855 determination of bilateral symmetry 1/376 133/18722 0.933324931122337 0.950995032368934 OFD1 1 GO:0046887 positive regulation of hormone secretion 1/376 133/18722 0.933324931122337 0.950995032368934 RAB8B 1 GO:0009799 specification of symmetry 1/376 134/18722 0.934673568805806 0.951618517898712 OFD1 1 GO:0032147 activation of protein kinase activity 1/376 134/18722 0.934673568805806 0.951618517898712 CCL5 1 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1/376 134/18722 0.934673568805806 0.951618517898712 RNF19A 1 GO:0001822 kidney development 3/376 293/18722 0.935995193550543 0.952713783821474 PRDM1/STAT1/CFLAR 3 GO:0071805 potassium ion transmembrane transport 2/376 219/18722 0.93651372507936 0.952991251229653 FLNA/VAMP2 2 GO:0072073 kidney epithelium development 1/376 136/18722 0.937289768149596 0.953530546489809 STAT1 1 GO:0007586 digestion 1/376 137/18722 0.938558413752509 0.954178630472745 EPB41 1 GO:0050714 positive regulation of protein secretion 1/376 137/18722 0.938558413752509 0.954178630472745 TGFB1 1 GO:0042391 regulation of membrane potential 5/376 434/18722 0.938665532738607 0.954178630472745 CALM1/FLNA/JUN/UCP2/CLIC1 5 GO:0015931 nucleobase-containing compound transport 2/376 222/18722 0.939627736840078 0.954906236626095 ZFP36/SRSF7 2 GO:0046165 alcohol biosynthetic process 1/376 140/18722 0.942212811801516 0.95728228781617 PLEK 1 GO:0072001 renal system development 3/376 302/18722 0.943998263334894 0.958844893950908 PRDM1/STAT1/CFLAR 3 GO:0006865 amino acid transport 1/376 143/18722 0.945650398651154 0.960271303661746 SLC9A3R1 1 GO:0044272 sulfur compound biosynthetic process 1/376 148/18722 0.950932412514306 0.965129150993436 CHST12 1 GO:0050905 neuromuscular process 1/376 148/18722 0.950932412514306 0.965129150993436 RCSD1 1 GO:0032368 regulation of lipid transport 1/376 149/18722 0.951925704906609 0.965631441495578 NFKBIA 1 GO:1905039 carboxylic acid transmembrane transport 1/376 149/18722 0.951925704906609 0.965631441495578 EMB 1 GO:1903825 organic acid transmembrane transport 1/376 150/18722 0.952898942130273 0.966196914734859 EMB 1 GO:0019318 hexose metabolic process 2/376 237/18722 0.953141999401493 0.966196914734859 RORA/TNF 2 GO:0046394 carboxylic acid biosynthetic process 3/376 314/18722 0.953231175491966 0.966196914734859 ALOX5AP/GLS/XBP1 3 GO:0009100 glycoprotein metabolic process 4/376 387/18722 0.95378981093231 0.966321188550541 ITM2A/MGAT4A/GNPTAB/CHST12 4 GO:0055067 monovalent inorganic cation homeostasis 1/376 151/18722 0.953852528053114 0.966321188550541 MLLT6 1 GO:0016053 organic acid biosynthetic process 3/376 316/18722 0.954624683581837 0.966850666199586 ALOX5AP/GLS/XBP1 3 GO:0009101 glycoprotein biosynthetic process 3/376 317/18722 0.955306821727061 0.967288720719195 ITM2A/MGAT4A/CHST12 3 GO:0006813 potassium ion transport 2/376 241/18722 0.956226593532444 0.96796709768501 FLNA/VAMP2 2 GO:0008202 steroid metabolic process 3/376 319/18722 0.956642475282611 0.968135176735471 RORA/TNF/SF1 3 GO:0046434 organophosphate catabolic process 1/376 155/18722 0.957478155572239 0.968727898914472 SAMHD1 1 GO:0090257 regulation of muscle system process 2/376 252/18722 0.963740343134251 0.974715361459098 CALM1/ROCK1 2 GO:0006633 fatty acid biosynthetic process 1/376 163/18722 0.963899165190004 0.974715361459098 XBP1 1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 1/376 167/18722 0.966737245615981 0.977330244393928 EMB 1 GO:0006937 regulation of muscle contraction 1/376 169/18722 0.968071700642017 0.978424058421444 CALM1 1 GO:0048515 spermatid differentiation 1/376 172/18722 0.969973927986142 0.98009099633541 DDX6 1 GO:0010498 proteasomal protein catabolic process 5/376 490/18722 0.970350454399727 0.980215852658744 PSMB9/PSMB8/PPP2R5C/PSME1/RNF19A 5 GO:0022900 electron transport chain 1/376 175/18722 0.971763107663933 0.98138703210783 CYBA 1 GO:0015698 inorganic anion transport 1/376 180/18722 0.974511878194318 0.983676540152036 CLIC1 1 GO:0015711 organic anion transport 3/376 354/18722 0.974740891902796 0.983676540152036 SLC2A3/EMB/SLC9A3R1 3 GO:0046942 carboxylic acid transport 2/376 273/18722 0.974791719789372 0.983676540152036 EMB/SLC9A3R1 2 GO:0006575 cellular modified amino acid metabolic process 1/376 188/18722 0.978365536945679 0.986768988980871 CLIC1 1 GO:0048839 inner ear development 1/376 188/18722 0.978365536945679 0.986768988980871 SLC9A3R1 1 GO:0048562 embryonic organ morphogenesis 2/376 285/18722 0.979564627997012 0.987721294168208 ID2/SLC9A3R1 2 GO:0010876 lipid localization 4/376 448/18722 0.980672803895501 0.98833668210688 TNF/PIP4K2A/APOL6/NFKBIA 4 GO:0001654 eye development 3/376 371/18722 0.980685043277666 0.98833668210688 PRDM1/VIM/STAT3 3 GO:1901605 alpha-amino acid metabolic process 1/376 195/18722 0.981257483557623 0.988656460942743 GLS 1 GO:0150063 visual system development 3/376 375/18722 0.981876058828038 0.9890225443095 PRDM1/VIM/STAT3 3 GO:0044282 small molecule catabolic process 3/376 376/18722 0.982162685873816 0.989054160021059 APOBEC3G/APOBEC3C/GLS 3 GO:0009952 anterior/posterior pattern specification 1/376 201/18722 0.983427297020617 0.989918713592575 BTG2 1 GO:0048880 sensory system development 3/376 381/18722 0.983532141246816 0.989918713592575 PRDM1/VIM/STAT3 3 GO:0022412 cellular process involved in reproduction in multicellular organism 3/376 384/18722 0.984304999105278 0.990439333038938 MYBL1/PRDM1/DDX6 3 GO:0015849 organic acid transport 2/376 303/18722 0.985124577232808 0.991006681406316 EMB/SLC9A3R1 2 GO:0030258 lipid modification 1/376 212/18722 0.9867753386184 0.992083921433234 DGKZ 1 GO:0043583 ear development 1/376 213/18722 0.987043975716158 0.992083921433234 SLC9A3R1 1 GO:0044242 cellular lipid catabolic process 1/376 214/18722 0.987307170115138 0.992083921433234 SORL1 1 GO:0072330 monocarboxylic acid biosynthetic process 1/376 214/18722 0.987307170115138 0.992083921433234 XBP1 1 GO:0006869 lipid transport 3/376 398/18722 0.987475531604641 0.992083921433234 PIP4K2A/APOL6/NFKBIA 3 GO:0016042 lipid catabolic process 2/376 320/18722 0.989009291717134 0.993367290151347 TNF/SORL1 2 GO:0006091 generation of precursor metabolites and energy 4/376 490/18722 0.989686321771383 0.993668903581838 CYBA/DDIT4/STAT3/PPP1R2 4 GO:0006486 protein glycosylation 1/376 226/18722 0.990078873994704 0.993668903581838 MGAT4A 1 GO:0043413 macromolecule glycosylation 1/376 226/18722 0.990078873994704 0.993668903581838 MGAT4A 1 GO:0003002 regionalization 2/376 331/18722 0.99097595609216 0.994311711511424 PRKACB/BTG2 2 GO:0046395 carboxylic acid catabolic process 1/376 236/18722 0.991921275493238 0.994869483444356 GLS 1 GO:0006790 sulfur compound metabolic process 2/376 339/18722 0.992186213292622 0.994869483444356 CHST12/CLIC1 2 GO:0016054 organic acid catabolic process 1/376 240/18722 0.992558818837647 0.994869483444356 GLS 1 GO:0070085 glycosylation 1/376 240/18722 0.992558818837647 0.994869483444356 MGAT4A 1 GO:0007389 pattern specification process 3/376 436/18722 0.993281865464691 0.995083207730662 PRKACB/OFD1/BTG2 3 GO:0098656 anion transmembrane transport 1/376 245/18722 0.993285638065084 0.995083207730662 EMB 1 GO:0007281 germ cell development 1/376 278/18722 0.996595187001239 0.99802126028701 PRDM1 1 GO:0006631 fatty acid metabolic process 2/376 390/18722 0.996914116868342 0.99802126028701 ALOX5AP/XBP1 2 GO:0006520 cellular amino acid metabolic process 1/376 284/18722 0.99699104479252 0.99802126028701 GLS 1 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 2/376 412/18722 0.997943959898419 0.998717160280572 PPP2R5C/RNF19A 2 GO:0015980 energy derivation by oxidation of organic compounds 1/376 318/18722 0.998507517539161 0.99888358388327 PPP1R2 1 GO:0043010 camera-type eye development 1/376 322/18722 0.998625807474526 0.99888358388327 VIM 1 GO:0006066 alcohol metabolic process 1/376 353/18722 0.999275810214767 0.999275810214767 PLEK 1