ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0003735 structural constituent of ribosome 73/377 182/18367 6.98279514363386e-76 3.44251800581149e-73 RPL13/RPS4X/RPL10/RPS6/RPS3A/RPS15A/RPL39/RPL30/RPS8/RPL35A/RPL28/RPL32/RPS27/RPL9/RPL11/RPL29/RPL5/RPL18A/RPS9/RPL34/RPL6/RPS27A/RPS18/RPL19/RPL38/RPL21/RPS29/RPL41/RPL12/RPL26/RPS2/RPS25/RPL3/RPL37/RPL36/RPL22/RPS3/RPL13A/RPS15/RPS13/RPS28/RPSA/RPS23/RPLP2/RPS24/RPL10A/RPS12/RPS10/RPS19/RPS21/RPS7/RPL14/RPL27/RPL36A/RPL7/RPS5/RPL24/RPL37A/RPL4/RPL35/RPL23A/RPS20/RPL7A/RPL17/UBA52/RPL18/RPL15/RPS14/RPS11/RPL31/RPLP1/RPS26/RSL24D1 73 GO:0019843 rRNA binding 18/377 68/18367 1.3958206157259e-15 3.44069781776435e-13 RPS4X/RPL9/RPL11/RPL5/RPS9/RPS18/RPL19/RPL12/RPL37/RPS3/RPS13/RPS5/RPL23A/RPS14/RPS11/GTF3A/EEF2/MTERF4 18 GO:0042608 T cell receptor binding 6/377 11/18367 3.04465319315788e-08 5.00338008075611e-06 CD3G/CD3E/HLA-E/HLA-A/LCK/FYN 6 GO:0045296 cadherin binding 23/377 332/18367 4.1330634314636e-07 5.09400067927889e-05 FXYD5/RPL29/RPL34/RPL6/RPS2/EEF1D/CNN2/RPL14/RPL24/RPL23A/EIF3E/RPL7A/RPL15/ZC3HAV1/EIF2S3/STAT1/EEF2/ARGLU1/RPS26/DNAJB1/SPTAN1/TMPO/CORO1B 23 GO:0048027 mRNA 5'-UTR binding 7/377 27/18367 9.04783753865724e-07 8.92116781311604e-05 RPS3A/RPL5/RPL41/RPL26/RPS13/RPS7/RPS14 7 GO:0055106 ubiquitin-protein transferase regulator activity 6/377 22/18367 4.05995817239002e-06 0.00033359322983138 RPL11/RPL5/RPL37/RPS15/RPS7/RPS20 6 GO:0045182 translation regulator activity 13/377 140/18367 6.38650085478393e-06 0.000449792131629783 EEF1B2/RPL10/RPS9/EEF1A1/RPL22/PABPC1/EEF1D/EIF3E/RPS14/EIF2S3/EEF2/EIF4A2/EIF3H 13 GO:0008097 5S rRNA binding 4/377 10/18367 3.32673493122973e-05 0.00205010040137032 RPL11/RPL5/GTF3A/EEF2 4 GO:0003779 actin binding 23/377 440/18367 4.32791641096087e-05 0.00237073643400412 TMSB4X/EVL/CXCR4/CORO1A/GMFG/FXYD5/ABLIM1/BIN1/EPB41/CNN2/TMSB10/MSN/LCP1/LSP1/RCSD1/MARCKSL1/WAS/WIPF1/EEF2/ADD3/TPM3/SPTAN1/CORO1B 23 GO:0043548 phosphatidylinositol 3-kinase binding 6/377 34/18367 5.94300218119447e-05 0.00292990007532887 CORO1A/LCK/HCST/PIK3IP1/FYN/CALM1 6 GO:0030695 GTPase regulator activity 24/377 488/18367 7.71790785935759e-05 0.00317077381221941 ARHGDIB/EEF1B2/RASGRP1/ACAP1/RHOH/TBC1D10C/ARHGAP15/GPSM3/DENND2D/FGD3/RGS10/TAGAP/RGS1/RASGRP2/EEF1D/JUN/SMAP2/ARHGEF1/ARHGAP30/CYTH1/WAS/CDC42SE1/NUCB2/AKAP13 24 GO:0060589 nucleoside-triphosphatase regulator activity 24/377 488/18367 7.71790785935759e-05 0.00317077381221941 ARHGDIB/EEF1B2/RASGRP1/ACAP1/RHOH/TBC1D10C/ARHGAP15/GPSM3/DENND2D/FGD3/RGS10/TAGAP/RGS1/RASGRP2/EEF1D/JUN/SMAP2/ARHGEF1/ARHGAP30/CYTH1/WAS/CDC42SE1/NUCB2/AKAP13 24 GO:0035591 signaling adaptor activity 8/377 81/18367 0.000254996568004689 0.00967025446356242 CD3G/CD3E/TRAT1/LAT/PAG1/CDC42SE2/STAT3/AKAP13 8 GO:0004715 non-membrane spanning protein tyrosine kinase activity 6/377 45/18367 0.000297641331963771 0.010097197854363 LCK/ITK/TXK/JAK1/FYN/CLK1 6 GO:0140678 molecular function inhibitor activity 10/377 128/18367 0.000312170775884995 0.010097197854363 LEF1/TXNIP/RPL11/RPL5/RPL37/RPS15/RPS7/RPS20/CALM1/BCL2 10 GO:0008135 translation factor activity, RNA binding 8/377 84/18367 0.000327698104806912 0.010097197854363 EEF1B2/EEF1A1/EEF1D/EIF3E/EIF2S3/EEF2/EIF4A2/EIF3H 8 GO:0090079 translation regulator activity, nucleic acid binding 9/377 108/18367 0.000384925389707842 0.0111628363015274 EEF1B2/EEF1A1/PABPC1/EEF1D/EIF3E/EIF2S3/EEF2/EIF4A2/EIF3H 9 GO:0003746 translation elongation factor activity 4/377 19/18367 0.000530357105460534 0.0145258918328913 EEF1B2/EEF1A1/EEF1D/EEF2 4 GO:0004857 enzyme inhibitor activity 7/377 70/18367 0.000573019475118948 0.0148683474333495 TXNIP/RPL11/RPL5/RPL37/RPS15/RPS7/RPS20 7 GO:0042605 peptide antigen binding 5/377 36/18367 0.00079229237380633 0.019530007014326 HLA-E/HLA-A/HLA-B/HLA-C/HLA-F 5 GO:0070412 R-SMAD binding 4/377 23/18367 0.00113560192075182 0.0266596069966974 RGCC/DDX5/JUN/FOS 4 GO:0097371 MDM2/MDM4 family protein binding 3/377 11/18367 0.00125230642070573 0.028063048427633 RPL37/RPS15/RPS20 3 GO:0005096 GTPase activator activity 20/377 462/18367 0.00146963554537868 0.031501318429204 ARHGDIB/EEF1B2/RASGRP1/ACAP1/TBC1D10C/ARHGAP15/DENND2D/FGD3/RGS10/TAGAP/RGS1/RASGRP2/EEF1D/JUN/SMAP2/ARHGEF1/ARHGAP30/CYTH1/NUCB2/AKAP13 20 GO:0003823 antigen binding 10/377 171/18367 0.00286134695281276 0.058776835322362 IL7R/TRBC2/TRBC1/CD48/HLA-E/HLA-A/HLA-B/HLA-C/ITGA4/HLA-F 10 GO:0051015 actin filament binding 11/377 217/18367 0.00535538879240297 0.105608266986187 CORO1A/ABLIM1/BIN1/LCP1/RCSD1/MARCKSL1/EEF2/ADD3/TPM3/SPTAN1/CORO1B 11 GO:0046332 SMAD binding 6/377 79/18367 0.00567516939354458 0.107609942731441 RGCC/DDX5/JUN/TOB1/FOS/TGFBR2 6 GO:0044389 ubiquitin-like protein ligase binding 14/377 316/18367 0.00594325603128491 0.108519452719387 CXCR4/TXNIP/RPL11/RPL5/RPS27A/JAK1/JUN/PRKACB/UBA52/TNFRSF14/STAT1/BCL2/UBE2L6/UBXN1 14 GO:0005085 guanyl-nucleotide exchange factor activity 11/377 223/18367 0.00653650756463273 0.115089222477283 EEF1B2/RASGRP1/DENND2D/FGD3/TAGAP/RASGRP2/EEF1D/ARHGEF1/CYTH1/NUCB2/AKAP13 11 GO:0031625 ubiquitin protein ligase binding 13/377 297/18367 0.00866967350307985 0.14231592152247 CXCR4/TXNIP/RPL11/RPL5/RPS27A/JAK1/JUN/PRKACB/UBA52/TNFRSF14/BCL2/UBE2L6/UBXN1 13 GO:0005516 calmodulin binding 10/377 201/18367 0.00878276118934707 0.14231592152247 CAMK4/EPB41/RGS1/DDX5/CNN2/MBP/MARCKSL1/VAMP2/ADD3/SPTAN1 10 GO:0019207 kinase regulator activity 11/377 233/18367 0.00894887133305591 0.14231592152247 RAC2/GMFG/RHOH/RGCC/STK4/CCND2/RPLP1/CALM1/CCNI/CCNL1/TAOK3 11 GO:0019887 protein kinase regulator activity 10/377 204/18367 0.00968883714066517 0.147749178182694 RAC2/GMFG/RGCC/STK4/CCND2/RPLP1/CALM1/CCNI/CCNL1/TAOK3 10 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/377 22/18367 0.00988990442196534 0.147749178182694 CD27/BIRC3/TNFAIP8 3 GO:0001046 core promoter sequence-specific DNA binding 4/377 42/18367 0.0105776347559236 0.153375703960892 FOXP1/FOS/STAT1/UBTF 4 GO:0001965 G-protein alpha-subunit binding 3/377 24/18367 0.0126119342773887 0.172713433298684 RGS10/RGS1/NUCB2 3 GO:0043274 phospholipase binding 3/377 24/18367 0.0126119342773887 0.172713433298684 LCK/FYN/WAS 3 GO:0004674 protein serine/threonine kinase activity 15/377 386/18367 0.0140332947481338 0.186984170562972 CAMK4/PASK/PIM2/STK17B/STK4/ATM/PRKACB/SNRK/STK17A/TGFBR2/CLK1/AAK1/TAOK3/PIM1/AKAP13 15 GO:0003714 transcription corepressor activity 9/377 187/18367 0.0153509347511613 0.199158179797961 TOB1/PBXIP1/N4BP2L2/BTG2/TRIM22/UXT/SF1/PFDN5/DNAJB1 9 GO:0004690 cyclic nucleotide-dependent protein kinase activity 2/377 10/18367 0.0169571359834139 0.208996700995576 PRKACB/AKAP13 2 GO:0005522 profilin binding 2/377 10/18367 0.0169571359834139 0.208996700995576 EVL/WIPF1 2 GO:0017124 SH3 domain binding 7/377 130/18367 0.0178674009673323 0.214844601875484 CD3E/EVL/SKAP1/WAS/WIPF1/SH3BGRL/SH3KBP1 7 GO:0030159 signaling receptor complex adaptor activity 4/377 50/18367 0.0191634342960713 0.215375011465183 CD3G/CD3E/TRAT1/LAT 4 GO:0003785 actin monomer binding 3/377 28/18367 0.0192221105567303 0.215375011465183 TMSB4X/CORO1A/TMSB10 3 GO:0050681 androgen receptor binding 3/377 28/18367 0.0192221105567303 0.215375011465183 DDX5/FOXP1/PRMT2 3 GO:0004143 diacylglycerol kinase activity 2/377 11/18367 0.0204470981084601 0.219356936064116 DGKA/DGKZ 2 GO:0003743 translation initiation factor activity 4/377 51/18367 0.0204673814583151 0.219356936064116 EIF3E/EIF2S3/EIF4A2/EIF3H 4 GO:0003924 GTPase activity 13/377 337/18367 0.0224726403132368 0.235723652647356 GIMAP7/ARHGDIB/ARL4C/RAC2/RHOH/EEF1A1/RGS10/RGS1/TUBA1A/EIF2S3/EEF2/GBP2/RAP1B 13 GO:0005095 GTPase inhibitor activity 2/377 12/18367 0.024207629262715 0.235803584254888 RHOH/CDC42SE1 2 GO:0035256 G protein-coupled glutamate receptor binding 2/377 12/18367 0.024207629262715 0.235803584254888 FYN/CALM1 2 GO:0061578 Lys63-specific deubiquitinase activity 2/377 12/18367 0.024207629262715 0.235803584254888 CYLD/TNFAIP3 2 GO:0005525 GTP binding 14/377 377/18367 0.0243934742332643 0.235803584254888 GIMAP7/GIMAP4/ARL4C/RAC2/GIMAP1/RHOH/EEF1A1/GIMAP2/TUBA1A/EIF2S3/SAMHD1/EEF2/GBP2/RAP1B 14 GO:0047485 protein N-terminus binding 6/377 110/18367 0.0259140417060379 0.245685049251474 EPB41/ATM/RPS21/EIF3E/ALOX5AP/CALM1 6 GO:0031386 protein tag 2/377 13/18367 0.0282262132593572 0.253772559334628 RPS27A/UBA52 2 GO:0072542 protein phosphatase activator activity 2/377 13/18367 0.0282262132593572 0.253772559334628 PPP2R5C/CALM1 2 GO:0019199 transmembrane receptor protein kinase activity 7/377 143/18367 0.0283113402908814 0.253772559334628 LCK/ITK/TXK/JAK1/FYN/TGFBR2/CLK1 7 GO:0016922 nuclear receptor binding 7/377 144/18367 0.0292553518093946 0.256936070701821 LEF1/DDX5/FOXP1/PRMT2/STAT1/STAT3/JUND 7 GO:0019956 chemokine binding 3/377 33/18367 0.0297066045233342 0.256936070701821 CCR7/CXCR4/ITGA4 3 GO:0004298 threonine-type endopeptidase activity 2/377 14/18367 0.0324907313561534 0.27149034845057 PSMB8/PSMB9 2 GO:0019992 diacylglycerol binding 2/377 14/18367 0.0324907313561534 0.27149034845057 RASGRP1/RASGRP2 2 GO:0140297 DNA-binding transcription factor binding 14/377 394/18367 0.0336443967350313 0.27644479317284 LEF1/RPS3/DDX5/JUN/FOXP1/PTMA/FOS/MTDH/COMMD6/PRMT2/STAT1/STAT3/BCL2/JUND 14 GO:0106310 protein serine kinase activity 13/377 360/18367 0.0356156164469018 0.28055076127564 CAMK4/PASK/PIM2/STK17B/STK4/ATM/PRKACB/SNRK/STK17A/CLK1/AAK1/TAOK3/PIM1 13 GO:0019001 guanyl nucleotide binding 14/377 398/18367 0.0361479937296272 0.28055076127564 GIMAP7/GIMAP4/ARL4C/RAC2/GIMAP1/RHOH/EEF1A1/GIMAP2/TUBA1A/EIF2S3/SAMHD1/EEF2/GBP2/RAP1B 14 GO:0032561 guanyl ribonucleotide binding 14/377 398/18367 0.0361479937296272 0.28055076127564 GIMAP7/GIMAP4/ARL4C/RAC2/GIMAP1/RHOH/EEF1A1/GIMAP2/TUBA1A/EIF2S3/SAMHD1/EEF2/GBP2/RAP1B 14 GO:0043621 protein self-association 4/377 61/18367 0.0365021115342723 0.28055076127564 CD2/FOXP1/TNFAIP3/VAMP2 4 GO:0071933 Arp2/3 complex binding 2/377 15/18367 0.0369894512838065 0.28055076127564 GMFG/CORO1B 2 GO:0051020 GTPase binding 11/377 291/18367 0.038563327263292 0.288056368800045 ARHGDIB/RHOH/FGD3/LCP1/CDC42SE2/WAS/SORL1/GCC2/CYFIP2/CDC42SE1/AKAP13 11 GO:0005521 lamin binding 2/377 16/18367 0.0417110165553663 0.296958477753023 SUN2/TMPO 2 GO:0016004 phospholipase activator activity 2/377 16/18367 0.0417110165553663 0.296958477753023 LCK/FYN 2 GO:0031267 small GTPase binding 10/377 259/18367 0.0418782406677392 0.296958477753023 ARHGDIB/RHOH/FGD3/CDC42SE2/WAS/SORL1/GCC2/CYFIP2/CDC42SE1/AKAP13 10 GO:0030674 protein-macromolecule adaptor activity 11/377 296/18367 0.0427165733550821 0.296958477753023 CD3G/CD3E/TRAT1/LAT/PAG1/CDC42SE2/TRIM22/VAMP2/STAT3/SUN2/AKAP13 11 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/377 124/18367 0.0427668395952629 0.296958477753023 LCK/ITK/TXK/JAK1/FYN/CLK1 6 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 11/377 299/18367 0.0453515483370804 0.310140123663519 LEF1/DDX5/JUN/FOXP1/FOS/MTDH/COMMD6/PRMT2/STAT1/STAT3/JUND 11 GO:0003712 transcription coregulator activity 16/377 489/18367 0.0459233854511904 0.310140123663519 ETS1/BTG1/TOB1/PBXIP1/MTDH/N4BP2L2/BTG2/PRMT2/TRIM22/UXT/SF1/PFDN5/MAML2/PSIP1/DNAJB1/KAT6A 16 GO:0003951 NAD+ kinase activity 2/377 17/18367 0.0466444360498351 0.310752796926604 DGKA/DGKZ 2 GO:0042169 SH2 domain binding 3/377 40/18367 0.0484816521141312 0.314151685140022 LCK/SKAP1/PAG1 3 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/377 40/18367 0.0484816521141312 0.314151685140022 CD27/BIRC3/TNFAIP8 3 GO:0004896 cytokine receptor activity 5/377 97/18367 0.049513852779436 0.314151685140022 IL7R/CCR7/IL2RG/CXCR4/CD44 5 GO:0019902 phosphatase binding 8/377 196/18367 0.0497035120505512 0.314151685140022 RCAN3/LCK/SKAP1/JAK1/STAT1/STAT3/BCL2/TERF2IP 8 GO:0060229 lipase activator activity 2/377 18/18367 0.0517790738632625 0.323127638159347 LCK/FYN 2 GO:0005200 structural constituent of cytoskeleton 5/377 103/18367 0.0610434899164519 0.367467984246388 EPB41/MSN/TUBA1A/ADD3/SPTAN1 5 GO:0004713 protein tyrosine kinase activity 6/377 136/18367 0.0616836815094617 0.367467984246388 LCK/ITK/TXK/JAK1/FYN/CLK1 6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/377 20/18367 0.062611177843198 0.367467984246388 FOS/STAT1 2 GO:0019211 phosphatase activator activity 2/377 20/18367 0.062611177843198 0.367467984246388 PPP2R5C/CALM1 2 GO:0042288 MHC class I protein binding 2/377 20/18367 0.062611177843198 0.367467984246388 HLA-E/CD8B 2 GO:0019955 cytokine binding 6/377 139/18367 0.0670770285317348 0.389046765484062 CCR7/IL2RG/CXCR4/ITGA4/TNFRSF14/TGFBR2 6 GO:0001618 virus receptor activity 4/377 76/18367 0.0710019102923077 0.406703923560718 CXCR4/RPSA/SELPLG/TNFRSF14 4 GO:0035254 glutamate receptor binding 3/377 47/18367 0.071771280628362 0.406703923560718 FYN/MYL12A/CALM1 3 GO:0140272 exogenous protein binding 4/377 77/18367 0.0737401652352315 0.413112516601922 CXCR4/RPSA/SELPLG/TNFRSF14 4 GO:0015026 coreceptor activity 3/377 48/18367 0.0754418163369805 0.413123646031215 CXCR4/CD8B/ITGA4 3 GO:0048020 CCR chemokine receptor binding 3/377 48/18367 0.0754418163369805 0.413123646031215 JAK1/STAT1/STAT3 3 GO:0008047 enzyme activator activity 5/377 110/18367 0.0762560888211777 0.413123646031215 GMFG/LCK/FYN/ALOX5AP/CALM1 5 GO:0016493 C-C chemokine receptor activity 2/377 23/18367 0.0801219215452724 0.424732336793756 CCR7/CXCR4 2 GO:0017134 fibroblast growth factor binding 2/377 23/18367 0.0801219215452724 0.424732336793756 RPS2/RPS19 2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/377 50/18367 0.0830254668383708 0.435442076077838 CCND2/CCNI/CCNL1 3 GO:0019957 C-C chemokine binding 2/377 24/18367 0.08625919311508 0.4429768979764 CCR7/CXCR4 2 GO:0070003 threonine-type peptidase activity 2/377 24/18367 0.08625919311508 0.4429768979764 PSMB8/PSMB9 2 GO:0019903 protein phosphatase binding 6/377 150/18367 0.0891224758328991 0.448340618220605 LCK/SKAP1/JAK1/STAT1/STAT3/BCL2 6 GO:0140677 molecular function activator activity 6/377 150/18367 0.0891224758328991 0.448340618220605 GMFG/LCK/FYN/ALOX5AP/CALM1/DNAJB1 6 GO:0035035 histone acetyltransferase binding 2/377 25/18367 0.0925323784638122 0.460792551339994 ETS1/STAT1 2 GO:0001637 G protein-coupled chemoattractant receptor activity 2/377 26/18367 0.0989333480713994 0.482912283160395 CCR7/CXCR4 2 GO:0004950 chemokine receptor activity 2/377 26/18367 0.0989333480713994 0.482912283160395 CCR7/CXCR4 2 GO:0030507 spectrin binding 2/377 27/18367 0.105454247300924 0.509695528621133 PTPRC/EPB41 2 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/377 56/18367 0.10759783332743 0.510055113754068 CD27/BIRC3/TNFAIP8 3 GO:0042054 histone methyltransferase activity 3/377 56/18367 0.10759783332743 0.510055113754068 KMT2A/PRMT2/FBL 3 GO:0019888 protein phosphatase regulator activity 4/377 89/18367 0.110577715779243 0.514290696973271 RCAN3/PPP2R5C/PPP1R2/CALM1 4 GO:0051117 ATPase binding 4/377 89/18367 0.110577715779243 0.514290696973271 LCK/DNAJB1/UBXN1/FBL 4 GO:0051059 NF-kappaB binding 2/377 29/18367 0.118825743839218 0.541712294325355 MTDH/COMMD6 2 GO:0036002 pre-mRNA binding 3/377 59/18367 0.120822761702403 0.541712294325355 DDX5/CELF2/SF1 3 GO:0043130 ubiquitin binding 4/377 92/18367 0.120863816669356 0.541712294325355 CXCR4/TNFAIP3/UBE2L6/UBXN1 4 GO:0003730 mRNA 3'-UTR binding 7/377 201/18367 0.120868868916408 0.541712294325355 ZFP36L2/RPL5/RPL41/PABPC1/DDX5/CELF2/RPS7 7 GO:0032934 sterol binding 3/377 60/18367 0.125358223833273 0.555687193233485 GPR183/RORA/OSBPL8 3 GO:0042277 peptide binding 10/377 321/18367 0.126241309618966 0.555687193233485 ITM2A/HLA-E/HLA-A/HLA-B/HLA-C/CRIP1/HLA-F/SORL1/PFDN5/LNPEP 10 GO:0005164 tumor necrosis factor receptor binding 2/377 31/18367 0.132589236924175 0.578464546934676 LTB/STAT1 2 GO:1990841 promoter-specific chromatin binding 3/377 62/18367 0.134608950744412 0.579131829048191 RBL2/DDX5/STAT1 3 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/377 450/18367 0.137154540637006 0.579131829048191 ETS1/LEF1/JUNB/BCL11B/JUN/PBXIP1/FOS/KLF6/IRF1/STAT3/KLF13/JUND/ELF1 13 GO:0001222 transcription corepressor binding 2/377 32/18367 0.139601050194575 0.579131829048191 RORA/STAT1 2 GO:0051721 protein phosphatase 2A binding 2/377 32/18367 0.139601050194575 0.579131829048191 STAT1/BCL2 2 GO:0071889 14-3-3 protein binding 2/377 32/18367 0.139601050194575 0.579131829048191 HLA-F/DDIT4 2 GO:0060090 molecular adaptor activity 11/377 369/18367 0.139790441494391 0.579131829048191 CD3G/CD3E/TRAT1/LAT/PAG1/CDC42SE2/TRIM22/VAMP2/STAT3/SUN2/AKAP13 11 GO:0002020 protease binding 5/377 135/18367 0.145151780655744 0.582340044260225 SELL/BIN1/MBP/TNFAIP3/BCL2 5 GO:0051427 hormone receptor binding 2/377 33/18367 0.14669101443143 0.582340044260225 JAK1/FYN 2 GO:0001216 DNA-binding transcription activator activity 13/377 456/18367 0.146994484549292 0.582340044260225 ETS1/LEF1/JUNB/BCL11B/JUN/PBXIP1/FOS/KLF6/IRF1/STAT3/KLF13/JUND/ELF1 13 GO:0016248 channel inhibitor activity 2/377 34/18367 0.153852991555692 0.582340044260225 CALM1/BCL2 2 GO:0030295 protein kinase activator activity 4/377 101/18367 0.154004480084128 0.582340044260225 RGCC/STK4/RPLP1/CALM1 4 GO:0000175 3'-5'-exoribonuclease activity 2/377 35/18367 0.161081061316819 0.582340044260225 ISG20/CNOT6L 2 GO:0061631 ubiquitin conjugating enzyme activity 2/377 36/18367 0.168369514976315 0.582340044260225 UBE2L6/UBE2D2 2 GO:0097718 disordered domain specific binding 2/377 36/18367 0.168369514976315 0.582340044260225 FYN/CALM1 2 GO:1990782 protein tyrosine kinase binding 4/377 105/18367 0.169723498697365 0.582340044260225 CD2/TRAT1/CD247/TOB1 4 GO:0140375 immune receptor activity 5/377 144/18367 0.174850011635782 0.582340044260225 IL7R/CCR7/IL2RG/CXCR4/CD44 5 GO:0019208 phosphatase regulator activity 4/377 107/18367 0.177786723852152 0.582340044260225 RCAN3/PPP2R5C/PPP1R2/CALM1 4 GO:0019209 kinase activator activity 4/377 107/18367 0.177786723852152 0.582340044260225 RGCC/STK4/RPLP1/CALM1 4 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters 2/377 38/18367 0.1831057598587 0.582340044260225 ISG20/CNOT6L 2 GO:0000049 tRNA binding 3/377 72/18367 0.183983498825788 0.582340044260225 RPL35A/EEF1A1/EIF2S3 3 GO:0042379 chemokine receptor binding 3/377 72/18367 0.183983498825788 0.582340044260225 JAK1/STAT1/STAT3 3 GO:0001094 TFIID-class transcription factor complex binding 1/377 10/18367 0.187343398561802 0.582340044260225 FBL 1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/377 10/18367 0.187343398561802 0.582340044260225 PTPN4 1 GO:0004955 prostaglandin receptor activity 1/377 10/18367 0.187343398561802 0.582340044260225 PTGER4 1 GO:0005031 tumor necrosis factor-activated receptor activity 1/377 10/18367 0.187343398561802 0.582340044260225 TNFRSF14 1 GO:0005528 FK506 binding 1/377 10/18367 0.187343398561802 0.582340044260225 FKBP5 1 GO:0008172 S-methyltransferase activity 1/377 10/18367 0.187343398561802 0.582340044260225 KMT2A 1 GO:0008330 protein tyrosine/threonine phosphatase activity 1/377 10/18367 0.187343398561802 0.582340044260225 DUSP2 1 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/377 10/18367 0.187343398561802 0.582340044260225 ATM 1 GO:0017002 activin-activated receptor activity 1/377 10/18367 0.187343398561802 0.582340044260225 TGFBR2 1 GO:0032356 oxidized DNA binding 1/377 10/18367 0.187343398561802 0.582340044260225 RPS3 1 GO:0034511 U3 snoRNA binding 1/377 10/18367 0.187343398561802 0.582340044260225 ISG20 1 GO:0034713 type I transforming growth factor beta receptor binding 1/377 10/18367 0.187343398561802 0.582340044260225 TGFBR2 1 GO:0035612 AP-2 adaptor complex binding 1/377 10/18367 0.187343398561802 0.582340044260225 AAK1 1 GO:0043208 glycosphingolipid binding 1/377 10/18367 0.187343398561802 0.582340044260225 SELL 1 GO:0070016 armadillo repeat domain binding 1/377 10/18367 0.187343398561802 0.582340044260225 LEF1 1 GO:0098505 G-rich strand telomeric DNA binding 1/377 10/18367 0.187343398561802 0.582340044260225 TERF2IP 1 GO:0004402 histone acetyltransferase activity 2/377 39/18367 0.190543136621835 0.582340044260225 EPC1/KAT6A 2 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/377 39/18367 0.190543136621835 0.582340044260225 UBE2L6/UBE2D2 2 GO:0043021 ribonucleoprotein complex binding 5/377 149/18367 0.192274827854649 0.582340044260225 RPSA/DDX5/RPLP1/EEF2/PIM1 5 GO:0008022 protein C-terminus binding 6/377 189/18367 0.193644573503189 0.582340044260225 CORO1A/LCK/EPB41/PABPC1/TNFAIP3/VAMP2 6 GO:0032182 ubiquitin-like protein binding 4/377 111/18367 0.194286647852101 0.582340044260225 CXCR4/TNFAIP3/UBE2L6/UBXN1 4 GO:0003725 double-stranded RNA binding 3/377 74/18367 0.194381226022661 0.582340044260225 MSN/MBNL1/MTDH 3 GO:0017022 myosin binding 3/377 74/18367 0.194381226022661 0.582340044260225 CXCR4/CORO1A/VAMP2 3 GO:0019210 kinase inhibitor activity 3/377 74/18367 0.194381226022661 0.582340044260225 GMFG/RHOH/TAOK3 3 GO:0005539 glycosaminoglycan binding 7/377 230/18367 0.195298004435377 0.582340044260225 PTPRC/SELL/SPOCK2/RPL29/RPL22/CD44/TGFBR2 7 GO:0004532 exoribonuclease activity 2/377 40/18367 0.198020056859083 0.582340044260225 ISG20/CNOT6L 2 GO:0042287 MHC protein binding 2/377 40/18367 0.198020056859083 0.582340044260225 HLA-E/CD8B 2 GO:0043014 alpha-tubulin binding 2/377 40/18367 0.198020056859083 0.582340044260225 ARL4C/FYN 2 GO:0033218 amide binding 11/377 400/18367 0.201485727870872 0.582340044260225 ITM2A/HLA-E/HLA-A/HLA-B/HLA-C/CRIP1/HLA-F/FKBP5/SORL1/PFDN5/LNPEP 11 GO:0004954 prostanoid receptor activity 1/377 11/18367 0.204033028607137 0.582340044260225 PTGER4 1 GO:0005078 MAP-kinase scaffold activity 1/377 11/18367 0.204033028607137 0.582340044260225 AKAP13 1 GO:0005536 glucose binding 1/377 11/18367 0.204033028607137 0.582340044260225 SLC2A3 1 GO:0016273 arginine N-methyltransferase activity 1/377 11/18367 0.204033028607137 0.582340044260225 PRMT2 1 GO:0016274 protein-arginine N-methyltransferase activity 1/377 11/18367 0.204033028607137 0.582340044260225 PRMT2 1 GO:0019855 calcium channel inhibitor activity 1/377 11/18367 0.204033028607137 0.582340044260225 CALM1 1 GO:0022889 serine transmembrane transporter activity 1/377 11/18367 0.204033028607137 0.582340044260225 SERINC5 1 GO:0051400 BH domain binding 1/377 11/18367 0.204033028607137 0.582340044260225 BCL2 1 GO:0070513 death domain binding 1/377 11/18367 0.204033028607137 0.582340044260225 BCL2 1 GO:0030331 estrogen receptor binding 2/377 41/18367 0.205531780327138 0.582340044260225 LEF1/PRMT2 2 GO:0061733 peptide-lysine-N-acetyltransferase activity 2/377 41/18367 0.205531780327138 0.582340044260225 EPC1/KAT6A 2 GO:0003724 RNA helicase activity 3/377 77/18367 0.210238256128137 0.582539628599708 DDX5/EIF4A2/DDX24 3 GO:0030971 receptor tyrosine kinase binding 3/377 78/18367 0.215586533430351 0.582539628599708 CD2/TRAT1/TOB1 3 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/377 12/18367 0.220380792183902 0.582539628599708 RPS3 1 GO:0005024 transforming growth factor beta-activated receptor activity 1/377 12/18367 0.220380792183902 0.582539628599708 TGFBR2 1 GO:0005527 macrolide binding 1/377 12/18367 0.220380792183902 0.582539628599708 FKBP5 1 GO:0008296 3'-5'-exodeoxyribonuclease activity 1/377 12/18367 0.220380792183902 0.582539628599708 ISG20 1 GO:0035004 phosphatidylinositol 3-kinase activity 1/377 12/18367 0.220380792183902 0.582539628599708 ATM 1 GO:0042975 peroxisome proliferator activated receptor binding 1/377 12/18367 0.220380792183902 0.582539628599708 PRMT2 1 GO:0043047 single-stranded telomeric DNA binding 1/377 12/18367 0.220380792183902 0.582539628599708 TERF2IP 1 GO:0043422 protein kinase B binding 1/377 12/18367 0.220380792183902 0.582539628599708 SRSF5 1 GO:0045295 gamma-catenin binding 1/377 12/18367 0.220380792183902 0.582539628599708 LEF1 1 GO:0030544 Hsp70 protein binding 2/377 43/18367 0.220641555580344 0.582539628599708 RPS3/DNAJB1 2 GO:0008186 ATP-dependent activity, acting on RNA 3/377 79/18367 0.220963307399889 0.582539628599708 DDX5/EIF4A2/DDX24 3 GO:0008375 acetylglucosaminyltransferase activity 2/377 44/18367 0.228230990910911 0.585935359588906 MGAT4A/OGT 2 GO:0140030 modification-dependent protein binding 5/377 160/18367 0.232571933057812 0.585935359588906 TNFAIP3/KMT2A/KMT2E/MPHOSPH8/UBXN1 5 GO:0048156 tau protein binding 2/377 45/18367 0.235837986507718 0.585935359588906 BIN1/FYN 2 GO:0004535 poly(A)-specific ribonuclease activity 1/377 13/18367 0.236393673760947 0.585935359588906 CNOT6L 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/377 13/18367 0.236393673760947 0.585935359588906 PPP1R2 1 GO:0005035 death receptor activity 1/377 13/18367 0.236393673760947 0.585935359588906 TNFRSF14 1 GO:0008179 adenylate cyclase binding 1/377 13/18367 0.236393673760947 0.585935359588906 CALM1 1 GO:0008494 translation activator activity 1/377 13/18367 0.236393673760947 0.585935359588906 PABPC1 1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/377 13/18367 0.236393673760947 0.585935359588906 DUSP2 1 GO:0031432 titin binding 1/377 13/18367 0.236393673760947 0.585935359588906 CALM1 1 GO:0032036 myosin heavy chain binding 1/377 13/18367 0.236393673760947 0.585935359588906 CORO1A 1 GO:0042393 histone binding 7/377 244/18367 0.236513461578483 0.585935359588906 LEF1/KMT2A/STAT1/KMT2E/ANP32B/MPHOSPH8/KAT6A 7 GO:0001540 amyloid-beta binding 3/377 84/18367 0.248217422141329 0.596601429387256 ITM2A/SORL1/PFDN5 3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/377 14/18367 0.252078515484393 0.596601429387256 TRAT1 1 GO:0005344 oxygen carrier activity 1/377 14/18367 0.252078515484393 0.596601429387256 IPCEF1 1 GO:0035259 glucocorticoid receptor binding 1/377 14/18367 0.252078515484393 0.596601429387256 STAT3 1 GO:0036041 long-chain fatty acid binding 1/377 14/18367 0.252078515484393 0.596601429387256 ALOX5AP 1 GO:0071837 HMG box domain binding 1/377 14/18367 0.252078515484393 0.596601429387256 JUN 1 GO:0008013 beta-catenin binding 3/377 85/18367 0.253731139922621 0.596601429387256 TCF7/LEF1/RORA 3 GO:0019783 ubiquitin-like protein-specific protease activity 4/377 125/18367 0.255236678854932 0.596601429387256 CYLD/TNFAIP3/SENP7/EIF3H 4 GO:0032813 tumor necrosis factor receptor superfamily binding 2/377 49/18367 0.266365698823408 0.596601429387256 LTB/STAT1 2 GO:0034212 peptide N-acetyltransferase activity 2/377 49/18367 0.266365698823408 0.596601429387256 EPC1/KAT6A 2 GO:0043539 protein serine/threonine kinase activator activity 2/377 49/18367 0.266365698823408 0.596601429387256 STK4/CALM1 2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/377 15/18367 0.267442020070149 0.596601429387256 PDE7A 1 GO:0004953 icosanoid receptor activity 1/377 15/18367 0.267442020070149 0.596601429387256 PTGER4 1 GO:0005041 low-density lipoprotein particle receptor activity 1/377 15/18367 0.267442020070149 0.596601429387256 SORL1 1 GO:0005545 1-phosphatidylinositol binding 1/377 15/18367 0.267442020070149 0.596601429387256 EPB41 1 GO:0010851 cyclase regulator activity 1/377 15/18367 0.267442020070149 0.596601429387256 CALM1 1 GO:0016846 carbon-sulfur lyase activity 1/377 15/18367 0.267442020070149 0.596601429387256 ALOX5AP 1 GO:0045125 bioactive lipid receptor activity 1/377 15/18367 0.267442020070149 0.596601429387256 S1PR4 1 GO:0048185 activin binding 1/377 15/18367 0.267442020070149 0.596601429387256 TGFBR2 1 GO:0050998 nitric-oxide synthase binding 1/377 15/18367 0.267442020070149 0.596601429387256 CALM1 1 GO:0070742 C2H2 zinc finger domain binding 1/377 15/18367 0.267442020070149 0.596601429387256 LEF1 1 GO:0098847 sequence-specific single stranded DNA binding 1/377 15/18367 0.267442020070149 0.596601429387256 TERF2IP 1 GO:0008276 protein methyltransferase activity 3/377 88/18367 0.270370374640988 0.597724639901377 KMT2A/PRMT2/FBL 3 GO:0048306 calcium-dependent protein binding 3/377 88/18367 0.270370374640988 0.597724639901377 DDX5/CALM1/VAMP2 3 GO:0004601 peroxidase activity 2/377 51/18367 0.281640366094138 0.602891521833057 IPCEF1/ALOX5AP 2 GO:0051018 protein kinase A binding 2/377 51/18367 0.281640366094138 0.602891521833057 RPS3/AKAP13 2 GO:0005092 GDP-dissociation inhibitor activity 1/377 16/18367 0.282490753637802 0.602891521833057 ARHGDIB 1 GO:0008191 metalloendopeptidase inhibitor activity 1/377 16/18367 0.282490753637802 0.602891521833057 SPOCK2 1 GO:0016208 AMP binding 1/377 16/18367 0.282490753637802 0.602891521833057 APRT 1 GO:0016307 phosphatidylinositol phosphate kinase activity 1/377 16/18367 0.282490753637802 0.602891521833057 PIP4K2A 1 GO:0035497 cAMP response element binding 1/377 16/18367 0.282490753637802 0.602891521833057 JUN 1 GO:0070492 oligosaccharide binding 1/377 16/18367 0.282490753637802 0.602891521833057 SELL 1 GO:0004879 nuclear receptor activity 2/377 52/18367 0.289269111987204 0.60551634795089 RORA/STAT3 2 GO:0031593 polyubiquitin modification-dependent protein binding 2/377 52/18367 0.289269111987204 0.60551634795089 TNFAIP3/UBXN1 2 GO:0098531 ligand-activated transcription factor activity 2/377 52/18367 0.289269111987204 0.60551634795089 RORA/STAT3 2 GO:0044325 transmembrane transporter binding 4/377 133/18367 0.291653129721368 0.60551634795089 FYN/CALM1/VAMP2/CRBN 4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/377 17/18367 0.297231148487049 0.60551634795089 PTPRC 1 GO:0019198 transmembrane receptor protein phosphatase activity 1/377 17/18367 0.297231148487049 0.60551634795089 PTPRC 1 GO:0030169 low-density lipoprotein particle binding 1/377 17/18367 0.297231148487049 0.60551634795089 SORL1 1 GO:0042800 histone methyltransferase activity (H3-K4 specific) 1/377 17/18367 0.297231148487049 0.60551634795089 KMT2A 1 GO:0043024 ribosomal small subunit binding 1/377 17/18367 0.297231148487049 0.60551634795089 PIM1 1 GO:0043395 heparan sulfate proteoglycan binding 1/377 17/18367 0.297231148487049 0.60551634795089 PTPRC 1 GO:0070064 proline-rich region binding 1/377 17/18367 0.297231148487049 0.60551634795089 CYLD 1 GO:0008408 3'-5' exonuclease activity 2/377 54/18367 0.304494758654618 0.615433902018205 ISG20/CNOT6L 2 GO:0004866 endopeptidase inhibitor activity 5/377 180/18367 0.310815146969665 0.615433902018205 CD27/SPOCK2/BIN1/BIRC3/TNFAIP8 5 GO:0008301 DNA binding, bending 1/377 18/18367 0.311669505817861 0.615433902018205 LEF1 1 GO:0030228 lipoprotein particle receptor activity 1/377 18/18367 0.311669505817861 0.615433902018205 SORL1 1 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/377 18/18367 0.311669505817861 0.615433902018205 TGFBR2 1 GO:0033549 MAP kinase phosphatase activity 1/377 18/18367 0.311669505817861 0.615433902018205 DUSP2 1 GO:0070122 isopeptidase activity 1/377 18/18367 0.311669505817861 0.615433902018205 EIF3H 1 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/377 55/18367 0.312086157210043 0.615433902018205 IPCEF1/ALOX5AP 2 GO:0050840 extracellular matrix binding 2/377 56/18367 0.319659798835325 0.62766515944564 SPOCK2/RPSA 2 GO:0008170 N-methyltransferase activity 3/377 97/18367 0.320834929371808 0.62766515944564 KMT2A/PRMT2/FBL 3 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/377 19/18367 0.325811998395476 0.629958050642564 TGFBR2 1 GO:0052742 phosphatidylinositol kinase activity 1/377 19/18367 0.325811998395476 0.629958050642564 ATM 1 GO:0016887 ATP hydrolysis activity 7/377 272/18367 0.325840371022016 0.629958050642564 DDX5/CHD3/RNF213/KIF2A/EIF4A2/DDX24/SMCHD1 7 GO:0004536 deoxyribonuclease activity 2/377 57/18367 0.327213218614493 0.630141081159942 ISG20/RPS3 2 GO:0019838 growth factor binding 4/377 141/18367 0.328703773840367 0.630548484448641 IL2RG/RPS2/RPS19/TGFBR2 4 GO:0061134 peptidase regulator activity 6/377 230/18367 0.334360627395263 0.636709824595297 MAL/CD27/SPOCK2/BIN1/BIRC3/TNFAIP8 6 GO:0005496 steroid binding 3/377 100/18367 0.337718245947195 0.636709824595297 GPR183/RORA/OSBPL8 3 GO:0030414 peptidase inhibitor activity 5/377 187/18367 0.339096498452431 0.636709824595297 CD27/SPOCK2/BIN1/BIRC3/TNFAIP8 5 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/377 20/18367 0.339664673161385 0.636709824595297 FBL 1 GO:0016505 peptidase activator activity involved in apoptotic process 1/377 20/18367 0.339664673161385 0.636709824595297 MAL 1 GO:0030506 ankyrin binding 1/377 20/18367 0.339664673161385 0.636709824595297 PTPRC 1 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/377 59/18367 0.342250070214313 0.636714281568515 ISG20/CNOT6L 2 GO:0098631 cell adhesion mediator activity 2/377 59/18367 0.342250070214313 0.636714281568515 RPSA/EMB 2 GO:0004725 protein tyrosine phosphatase activity 3/377 102/18367 0.348962164929843 0.644978121182003 PTPRC/DUSP2/PTPN4 3 GO:0051428 peptide hormone receptor binding 1/377 21/18367 0.353233453791361 0.644978121182003 FYN 1 GO:0070577 lysine-acetylated histone binding 1/377 21/18367 0.353233453791361 0.644978121182003 KMT2A 1 GO:0140033 acetylation-dependent protein binding 1/377 21/18367 0.353233453791361 0.644978121182003 KMT2A 1 GO:0140416 transcription regulator inhibitor activity 1/377 21/18367 0.353233453791361 0.644978121182003 LEF1 1 GO:0004602 glutathione peroxidase activity 1/377 22/18367 0.366524143201622 0.647180645011071 ALOX5AP 1 GO:0005355 glucose transmembrane transporter activity 1/377 22/18367 0.366524143201622 0.647180645011071 SLC2A3 1 GO:0005540 hyaluronic acid binding 1/377 22/18367 0.366524143201622 0.647180645011071 CD44 1 GO:0008320 protein transmembrane transporter activity 1/377 22/18367 0.366524143201622 0.647180645011071 TOMM7 1 GO:0008649 rRNA methyltransferase activity 1/377 22/18367 0.366524143201622 0.647180645011071 FBL 1 GO:0015149 hexose transmembrane transporter activity 1/377 22/18367 0.366524143201622 0.647180645011071 SLC2A3 1 GO:0017075 syntaxin-1 binding 1/377 22/18367 0.366524143201622 0.647180645011071 VAMP2 1 GO:0050321 tau-protein kinase activity 1/377 22/18367 0.366524143201622 0.647180645011071 FYN 1 GO:0140102 catalytic activity, acting on a rRNA 1/377 22/18367 0.366524143201622 0.647180645011071 FBL 1 GO:0061135 endopeptidase regulator activity 5/377 194/18367 0.367567100614807 0.647180645011071 CD27/SPOCK2/BIN1/BIRC3/TNFAIP8 5 GO:0051087 chaperone binding 3/377 107/18367 0.376966175343921 0.64745472671302 HLA-B/BIN1/DNAJB1 3 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/377 23/18367 0.379542426004184 0.64745472671302 PDE7A 1 GO:0004529 exodeoxyribonuclease activity 1/377 23/18367 0.379542426004184 0.64745472671302 ISG20 1 GO:0008143 poly(A) binding 1/377 23/18367 0.379542426004184 0.64745472671302 PABPC1 1 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/377 23/18367 0.379542426004184 0.64745472671302 CAMK4 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/377 23/18367 0.379542426004184 0.64745472671302 ALOX5AP 1 GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/377 23/18367 0.379542426004184 0.64745472671302 ISG20 1 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/377 23/18367 0.379542426004184 0.64745472671302 TNFAIP3 1 GO:0140103 catalytic activity, acting on a glycoprotein 1/377 23/18367 0.379542426004184 0.64745472671302 MGAT4A 1 GO:0010857 calcium-dependent protein kinase activity 1/377 24/18367 0.392293870912406 0.656103438863678 CAMK4 1 GO:0015145 monosaccharide transmembrane transporter activity 1/377 24/18367 0.392293870912406 0.656103438863678 SLC2A3 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/377 24/18367 0.392293870912406 0.656103438863678 ALOX5AP 1 GO:0043495 protein-membrane adaptor activity 1/377 24/18367 0.392293870912406 0.656103438863678 SUN2 1 GO:0050431 transforming growth factor beta binding 1/377 24/18367 0.392293870912406 0.656103438863678 TGFBR2 1 GO:0002039 p53 binding 2/377 66/18367 0.393928231041884 0.656103438863678 EEF2/MDM4 2 GO:0043022 ribosome binding 2/377 66/18367 0.393928231041884 0.656103438863678 RPSA/EEF2 2 GO:0004386 helicase activity 4/377 156/18367 0.398570547505906 0.658608841640916 DDX5/CHD3/EIF4A2/DDX24 4 GO:0097110 scaffold protein binding 2/377 67/18367 0.401166047601873 0.658608841640916 FYN/UBTF 2 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/377 25/18367 0.404783933097764 0.658608841640916 PDE7A 1 GO:0005112 Notch binding 1/377 25/18367 0.404783933097764 0.658608841640916 AAK1 1 GO:0005160 transforming growth factor beta receptor binding 1/377 25/18367 0.404783933097764 0.658608841640916 TGFBR2 1 GO:0008266 poly(U) RNA binding 1/377 25/18367 0.404783933097764 0.658608841640916 PABPC1 1 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/377 25/18367 0.404783933097764 0.658608841640916 ZFP36L2 1 GO:0008080 N-acetyltransferase activity 2/377 68/18367 0.408362964925216 0.662246518776748 EPC1/KAT6A 2 GO:0101005 deubiquitinase activity 3/377 114/18367 0.41571960226506 0.667499521278952 CYLD/TNFAIP3/EIF3H 3 GO:0004364 glutathione transferase activity 1/377 26/18367 0.417017956498818 0.667499521278952 ALOX5AP 1 GO:0042923 neuropeptide binding 1/377 26/18367 0.417017956498818 0.667499521278952 SORL1 1 GO:0042974 retinoic acid receptor binding 1/377 26/18367 0.417017956498818 0.667499521278952 PRMT2 1 GO:0004860 protein kinase inhibitor activity 2/377 70/18367 0.422628690080168 0.66929613863637 GMFG/TAOK3 2 GO:0004540 ribonuclease activity 3/377 116/18367 0.426656655065106 0.66929613863637 ISG20/SAMHD1/CNOT6L 3 GO:0001671 ATPase activator activity 1/377 27/18367 0.429001176083353 0.66929613863637 DNAJB1 1 GO:0004683 calmodulin-dependent protein kinase activity 1/377 27/18367 0.429001176083353 0.66929613863637 CAMK4 1 GO:0022884 macromolecule transmembrane transporter activity 1/377 27/18367 0.429001176083353 0.66929613863637 TOMM7 1 GO:0023026 MHC class II protein complex binding 1/377 27/18367 0.429001176083353 0.66929613863637 B2M 1 GO:0051119 sugar transmembrane transporter activity 1/377 27/18367 0.429001176083353 0.66929613863637 SLC2A3 1 GO:0070006 metalloaminopeptidase activity 1/377 27/18367 0.429001176083353 0.66929613863637 LNPEP 1 GO:0001968 fibronectin binding 1/377 28/18367 0.440738720064627 0.674343560462845 ITGA4 1 GO:0008187 poly-pyrimidine tract binding 1/377 28/18367 0.440738720064627 0.674343560462845 PABPC1 1 GO:0043236 laminin binding 1/377 28/18367 0.440738720064627 0.674343560462845 RPSA 1 GO:0046875 ephrin receptor binding 1/377 28/18367 0.440738720064627 0.674343560462845 FYN 1 GO:0051861 glycolipid binding 1/377 28/18367 0.440738720064627 0.674343560462845 SELL 1 GO:0035064 methylated histone binding 2/377 73/18367 0.443688580839819 0.674343560462845 KMT2E/MPHOSPH8 2 GO:0070063 RNA polymerase binding 2/377 73/18367 0.443688580839819 0.674343560462845 BIN1/ANP32B 2 GO:0140034 methylation-dependent protein binding 2/377 73/18367 0.443688580839819 0.674343560462845 KMT2E/MPHOSPH8 2 GO:0008201 heparin binding 4/377 166/18367 0.444546971907555 0.674343560462845 PTPRC/SELL/RPL29/RPL22 4 GO:0003713 transcription coactivator activity 6/377 262/18367 0.451151340076411 0.677666129944772 ETS1/MTDH/PRMT2/TRIM22/MAML2/KAT6A 6 GO:0046625 sphingolipid binding 1/377 29/18367 0.452235612072678 0.677666129944772 SELL 1 GO:0070273 phosphatidylinositol-4-phosphate binding 1/377 29/18367 0.452235612072678 0.677666129944772 OSBPL8 1 GO:0070717 poly-purine tract binding 1/377 29/18367 0.452235612072678 0.677666129944772 PABPC1 1 GO:0051082 unfolded protein binding 3/377 122/18367 0.459010912832888 0.685734484929133 NACA/PFDN5/DNAJB1 3 GO:0046966 thyroid hormone receptor binding 1/377 30/18367 0.463496773281566 0.689500886724634 PRMT2 1 GO:0003697 single-stranded DNA binding 3/377 123/18367 0.464329197550869 0.689500886724634 SAMHD1/SMC4/TERF2IP 3 GO:0031210 phosphatidylcholine binding 1/377 31/18367 0.474527024493479 0.694189385980075 RASGRP1 1 GO:0071813 lipoprotein particle binding 1/377 31/18367 0.474527024493479 0.694189385980075 SORL1 1 GO:0071814 protein-lipid complex binding 1/377 31/18367 0.474527024493479 0.694189385980075 SORL1 1 GO:0090482 vitamin transmembrane transporter activity 1/377 31/18367 0.474527024493479 0.694189385980075 SLC2A3 1 GO:0140318 protein transporter activity 1/377 31/18367 0.474527024493479 0.694189385980075 TOMM7 1 GO:0001221 transcription coregulator binding 2/377 78/18367 0.477815384440689 0.6969319068913 RORA/STAT1 2 GO:0004721 phosphoprotein phosphatase activity 4/377 174/18367 0.480547430661644 0.69757500429448 PTPRC/LCK/DUSP2/PTPN4 4 GO:0034987 immunoglobulin receptor binding 2/377 79/18367 0.484486866961229 0.69757500429448 TRBC2/TRBC1 2 GO:0001223 transcription coactivator binding 1/377 32/18367 0.485331088180541 0.69757500429448 RORA 1 GO:0030515 snoRNA binding 1/377 32/18367 0.485331088180541 0.69757500429448 ISG20 1 GO:0140658 ATP-dependent chromatin remodeler activity 1/377 32/18367 0.485331088180541 0.69757500429448 CHD3 1 GO:0004527 exonuclease activity 2/377 80/18367 0.491105327044936 0.702544253187367 ISG20/CNOT6L 2 GO:0031072 heat shock protein binding 3/377 129/18367 0.495736924730632 0.702544253187367 RPS3/FKBP5/DNAJB1 3 GO:0001530 lipopolysaccharide binding 1/377 33/18367 0.495913590485201 0.702544253187367 ZRANB2 1 GO:0008200 ion channel inhibitor activity 1/377 33/18367 0.495913590485201 0.702544253187367 CALM1 1 GO:0031369 translation initiation factor binding 1/377 33/18367 0.495913590485201 0.702544253187367 RPS24 1 GO:0000217 DNA secondary structure binding 1/377 36/18367 0.526376586462389 0.733061178321914 KMT2A 1 GO:0005484 SNAP receptor activity 1/377 36/18367 0.526376586462389 0.733061178321914 VAMP2 1 GO:0015248 sterol transporter activity 1/377 36/18367 0.526376586462389 0.733061178321914 OSBPL8 1 GO:0023023 MHC protein complex binding 1/377 36/18367 0.526376586462389 0.733061178321914 B2M 1 GO:0042162 telomeric DNA binding 1/377 36/18367 0.526376586462389 0.733061178321914 TERF2IP 1 GO:0043394 proteoglycan binding 1/377 36/18367 0.526376586462389 0.733061178321914 PTPRC 1 GO:0016209 antioxidant activity 2/377 86/18367 0.529670168951361 0.735570121952172 IPCEF1/ALOX5AP 2 GO:0051219 phosphoprotein binding 2/377 88/18367 0.542077352439485 0.74724844923466 LCK/EPB41 2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/377 38/18367 0.545658096804214 0.74724844923466 FKBP5 1 GO:0004520 endodeoxyribonuclease activity 1/377 38/18367 0.545658096804214 0.74724844923466 RPS3 1 GO:0015175 neutral amino acid transmembrane transporter activity 1/377 38/18367 0.545658096804214 0.74724844923466 SERINC5 1 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/377 38/18367 0.545658096804214 0.74724844923466 RPS3 1 GO:0008234 cysteine-type peptidase activity 4/377 190/18367 0.54953323410825 0.750470593948386 CYLD/TNFAIP3/SENP7/EIF3H 4 GO:0005504 fatty acid binding 1/377 39/18367 0.555003227335329 0.751693931528345 ALOX5AP 1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/377 39/18367 0.555003227335329 0.751693931528345 OGT 1 GO:0050997 quaternary ammonium group binding 1/377 39/18367 0.555003227335329 0.751693931528345 RASGRP1 1 GO:0016407 acetyltransferase activity 2/377 91/18367 0.560258843816246 0.751700606723574 EPC1/KAT6A 2 GO:0003925 G protein activity 1/377 40/18367 0.564156641962925 0.751700606723574 RAP1B 1 GO:0004177 aminopeptidase activity 1/377 40/18367 0.564156641962925 0.751700606723574 LNPEP 1 GO:0015144 carbohydrate transmembrane transporter activity 1/377 40/18367 0.564156641962925 0.751700606723574 SLC2A3 1 GO:0017080 sodium channel regulator activity 1/377 40/18367 0.564156641962925 0.751700606723574 FXYD5 1 GO:0044183 protein folding chaperone 1/377 40/18367 0.564156641962925 0.751700606723574 DNAJB1 1 GO:0001664 G protein-coupled receptor binding 6/377 295/18367 0.566229171451774 0.75242852163268 JAK1/ARHGEF1/FYN/STAT1/CALM1/STAT3 6 GO:0005178 integrin binding 3/377 144/18367 0.569920059407176 0.755297283031553 ITGA4/LCP1/ICAM3 3 GO:0016859 cis-trans isomerase activity 1/377 41/18367 0.57312226350382 0.755436835619159 FKBP5 1 GO:0048487 beta-tubulin binding 1/377 41/18367 0.57312226350382 0.755436835619159 UXT 1 GO:0016247 channel regulator activity 3/377 145/18367 0.574622339466906 0.755436835619159 FXYD5/CALM1/BCL2 3 GO:0016410 N-acyltransferase activity 2/377 94/18367 0.577919952516677 0.757751427102983 EPC1/KAT6A 2 GO:0005246 calcium channel regulator activity 1/377 43/18367 0.590505419934893 0.768124464453568 CALM1 1 GO:0016504 peptidase activator activity 1/377 43/18367 0.590505419934893 0.768124464453568 MAL 1 GO:0018024 histone-lysine N-methyltransferase activity 1/377 43/18367 0.590505419934893 0.768124464453568 KMT2A 1 GO:0001784 phosphotyrosine residue binding 1/377 44/18367 0.598930406656381 0.772965158328785 LCK 1 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/377 44/18367 0.598930406656381 0.772965158328785 CLK1 1 GO:0051879 Hsp90 protein binding 1/377 44/18367 0.598930406656381 0.772965158328785 RPS3 1 GO:0004722 protein serine/threonine phosphatase activity 2/377 98/18367 0.600652850150666 0.773164112596027 LCK/DUSP2 2 GO:0140223 general transcription initiation factor activity 1/377 45/18367 0.607182507114305 0.779533791685814 UBTF 1 GO:0004864 protein phosphatase inhibitor activity 1/377 46/18367 0.615265259806037 0.78581806498543 PPP1R2 1 GO:0140296 general transcription initiation factor binding 1/377 46/18367 0.615265259806037 0.78581806498543 FBL 1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/377 47/18367 0.623182130995007 0.791062219531196 DUSP2 1 GO:0001217 DNA-binding transcription repressor activity 6/377 313/18367 0.623897241442609 0.791062219531196 TCF7/LEF1/SATB1/JUN/FOXP1/IFI16 6 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/377 156/18367 0.624184996749767 0.791062219531196 KMT2A/PRMT2/FBL 3 GO:0004518 nuclease activity 4/377 210/18367 0.628501494126586 0.79449035026771 ISG20/RPS3/SAMHD1/CNOT6L 4 GO:0120013 lipid transfer activity 1/377 48/18367 0.630936516181409 0.795528650837429 OSBPL8 1 GO:0016763 pentosyltransferase activity 1/377 49/18367 0.638531741543034 0.798974996397756 APRT 1 GO:0019212 phosphatase inhibitor activity 1/377 49/18367 0.638531741543034 0.798974996397756 PPP1R2 1 GO:0098632 cell-cell adhesion mediator activity 1/377 49/18367 0.638531741543034 0.798974996397756 EMB 1 GO:0015485 cholesterol binding 1/377 50/18367 0.645971065346849 0.806237304344295 OSBPL8 1 GO:0015631 tubulin binding 7/377 375/18367 0.65286994893419 0.81103700764499 ARL4C/RPS3/FYN/KIF2A/UXT/SUN2/CCDC66 7 GO:0005126 cytokine receptor binding 5/377 271/18367 0.656397091380023 0.81103700764499 LTB/JAK1/STAT1/STAT3/TGFBR2 5 GO:0008017 microtubule binding 5/377 271/18367 0.656397091380023 0.81103700764499 RPS3/KIF2A/UXT/SUN2/CCDC66 5 GO:0030246 carbohydrate binding 5/377 271/18367 0.656397091380023 0.81103700764499 CD69/SELL/CLEC2D/SLC2A3/CLEC2B 5 GO:0017069 snRNA binding 1/377 53/18367 0.66738522026376 0.82106477470794 ISG20 1 GO:0004842 ubiquitin-protein transferase activity 8/377 433/18367 0.667843761983537 0.82106477470794 NOSIP/BIRC3/TNFAIP3/RNF213/TRIM22/UBE2L6/UBE2D2/TTC3 8 GO:0004843 thiol-dependent deubiquitinase 2/377 113/18367 0.677641611570295 0.831038095781481 CYLD/TNFAIP3 2 GO:0140098 catalytic activity, acting on RNA 7/377 386/18367 0.682155128613377 0.834497465028275 ISG20/DDX5/SAMHD1/EIF4A2/DDX24/CNOT6L/FBL 7 GO:0030374 nuclear receptor coactivator activity 1/377 56/18367 0.68750732430434 0.836891631807505 ETS1 1 GO:0045309 protein phosphorylated amino acid binding 1/377 56/18367 0.68750732430434 0.836891631807505 LCK 1 GO:0005548 phospholipid transporter activity 1/377 57/18367 0.69394114762023 0.842642822110279 OSBPL8 1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/377 58/18367 0.700242850916089 0.848205713763223 ALOX5AP 1 GO:0016279 protein-lysine N-methyltransferase activity 1/377 59/18367 0.706415140238533 0.853584961121561 KMT2A 1 GO:0001786 phosphatidylserine binding 1/377 60/18367 0.712460666354443 0.856690508567659 OSBPL8 1 GO:0016278 lysine N-methyltransferase activity 1/377 60/18367 0.712460666354443 0.856690508567659 KMT2A 1 GO:0015179 L-amino acid transmembrane transporter activity 1/377 61/18367 0.718382025877269 0.861708853424558 SERINC5 1 GO:0019787 ubiquitin-like protein transferase activity 8/377 458/18367 0.726795033821229 0.869684348722975 NOSIP/BIRC3/TNFAIP3/RNF213/TRIM22/UBE2L6/UBE2D2/TTC3 8 GO:0008242 omega peptidase activity 2/377 126/18367 0.734205855946345 0.876424907945637 CYLD/TNFAIP3 2 GO:0008173 RNA methyltransferase activity 1/377 65/18367 0.740875896104108 0.880124859709217 FBL 1 GO:0030145 manganese ion binding 1/377 65/18367 0.740875896104108 0.880124859709217 PIM1 1 GO:0005543 phospholipid binding 8/377 466/18367 0.744095084758034 0.881824223042574 RASGRP1/PASK/BIN1/EPB41/VAMP2/OGT/BIN2/OSBPL8 8 GO:0003684 damaged DNA binding 1/377 68/18367 0.756562120809813 0.886394407167753 RPS3 1 GO:0051536 iron-sulfur cluster binding 1/377 68/18367 0.756562120809813 0.886394407167753 RPS3 1 GO:0051540 metal cluster binding 1/377 68/18367 0.756562120809813 0.886394407167753 RPS3 1 GO:0003777 microtubule motor activity 1/377 69/18367 0.761577481236869 0.886394407167753 KIF2A 1 GO:0005518 collagen binding 1/377 69/18367 0.761577481236869 0.886394407167753 CD44 1 GO:0042578 phosphoric ester hydrolase activity 6/377 366/18367 0.765506932310242 0.886394407167753 PTPRC/LCK/DUSP2/PTPN4/SAMHD1/PDE7A 6 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/377 310/18367 0.765848532938105 0.886394407167753 LEF1/SATB1/JUN/FOXP1/IFI16 5 GO:0001098 basal transcription machinery binding 1/377 70/18367 0.766489782557981 0.886394407167753 FBL 1 GO:0001099 basal RNA polymerase II transcription machinery binding 1/377 70/18367 0.766489782557981 0.886394407167753 FBL 1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/377 71/18367 0.771301136986338 0.886394407167753 GLS 1 GO:0048029 monosaccharide binding 1/377 71/18367 0.771301136986338 0.886394407167753 SLC2A3 1 GO:0003678 DNA helicase activity 1/377 72/18367 0.776013613558055 0.886394407167753 CHD3 1 GO:0008235 metalloexopeptidase activity 1/377 72/18367 0.776013613558055 0.886394407167753 LNPEP 1 GO:0030276 clathrin binding 1/377 72/18367 0.776013613558055 0.886394407167753 BIN1 1 GO:0033293 monocarboxylic acid binding 1/377 73/18367 0.780629239012475 0.886394407167753 ALOX5AP 1 GO:0106306 protein serine phosphatase activity 1/377 73/18367 0.780629239012475 0.886394407167753 DUSP2 1 GO:0106307 protein threonine phosphatase activity 1/377 73/18367 0.780629239012475 0.886394407167753 DUSP2 1 GO:0140104 molecular carrier activity 1/377 73/18367 0.780629239012475 0.886394407167753 IPCEF1 1 GO:0099106 ion channel regulator activity 2/377 139/18367 0.782112712206841 0.886394407167753 FXYD5/CALM1 2 GO:0019905 syntaxin binding 1/377 74/18367 0.78514999865456 0.887795755359399 VAMP2 1 GO:0019003 GDP binding 1/377 75/18367 0.789577837199754 0.89075943647478 RAP1B 1 GO:0008194 UDP-glycosyltransferase activity 2/377 143/18367 0.79525210075978 0.894280789171578 MGAT4A/OGT 2 GO:1901681 sulfur compound binding 4/377 265/18367 0.796327112467186 0.894280789171578 PTPRC/SELL/RPL29/RPL22 4 GO:0038024 cargo receptor activity 1/377 77/18367 0.798162331862892 0.894304612746377 SORL1 1 GO:0016835 carbon-oxygen lyase activity 1/377 79/18367 0.80639749996875 0.900881890090696 RPS3 1 GO:0008528 G protein-coupled peptide receptor activity 2/377 147/18367 0.807687211805451 0.900881890090696 CCR7/CXCR4 2 GO:0035091 phosphatidylinositol binding 4/377 271/18367 0.810288643817655 0.901743344022808 PASK/EPB41/OGT/OSBPL8 4 GO:0008168 methyltransferase activity 3/377 214/18367 0.818581522116728 0.907514951208189 KMT2A/PRMT2/FBL 3 GO:0016791 phosphatase activity 4/377 275/18367 0.81915649754086 0.907514951208189 PTPRC/LCK/DUSP2/PTPN4 4 GO:0001653 peptide receptor activity 2/377 153/18367 0.82508171415628 0.910504558485383 CCR7/CXCR4 2 GO:0015171 amino acid transmembrane transporter activity 1/377 84/18367 0.825548757896483 0.910504558485383 SERINC5 1 GO:0000287 magnesium ion binding 3/377 221/18367 0.835021851818382 0.918056046868434 STK4/PRKACB/SNRK 3 GO:0003727 single-stranded RNA binding 1/377 87/18367 0.836120010231089 0.918056046868434 PABPC1 1 GO:0008081 phosphoric diester hydrolase activity 1/377 89/18367 0.842810088880614 0.920371726026776 PDE7A 1 GO:0043178 alcohol binding 1/377 89/18367 0.842810088880614 0.920371726026776 OSBPL8 1 GO:0016741 transferase activity, transferring one-carbon groups 3/377 225/18367 0.84382965550528 0.920371726026776 KMT2A/PRMT2/FBL 3 GO:0140097 catalytic activity, acting on DNA 3/377 229/18367 0.852227998567757 0.92555635941485 ISG20/RPS3/CHD3 3 GO:0051213 dioxygenase activity 1/377 92/18367 0.85233790501895 0.92555635941485 ALOX5AP 1 GO:0072341 modified amino acid binding 1/377 93/18367 0.85538406697834 0.926822736308399 OSBPL8 1 GO:0005125 cytokine activity 3/377 235/18367 0.864088118123155 0.934200531216481 LTB/IL32/IL16 3 GO:1901981 phosphatidylinositol phosphate binding 2/377 173/18367 0.87329840643969 0.940196104005239 OGT/OSBPL8 2 GO:0061630 ubiquitin protein ligase activity 4/377 304/18367 0.873701988700791 0.940196104005239 NOSIP/BIRC3/TRIM22/UBE2D2 4 GO:0004252 serine-type endopeptidase activity 2/377 174/18367 0.875354993384188 0.940196104005239 GZMM/GZMA 2 GO:0008238 exopeptidase activity 1/377 103/18367 0.882602247400872 0.943867479324576 LNPEP 1 GO:0031490 chromatin DNA binding 1/377 103/18367 0.882602247400872 0.943867479324576 STAT3 1 GO:0061659 ubiquitin-like protein ligase activity 4/377 316/18367 0.89175533748637 0.951591734590434 NOSIP/BIRC3/TRIM22/UBE2D2 4 GO:0008514 organic anion transmembrane transporter activity 2/377 185/18367 0.896032646552649 0.954090917387594 SLC2A3/SERINC5 2 GO:0000149 SNARE binding 1/377 110/18367 0.898552694741486 0.954712238162829 VAMP2 1 GO:0008094 ATP-dependent activity, acting on DNA 1/377 111/18367 0.900647542420867 0.95488008260965 CHD3 1 GO:0008237 metallopeptidase activity 2/377 190/18367 0.904337329964012 0.955110326566749 EIF3H/LNPEP 2 GO:0008236 serine-type peptidase activity 2/377 191/18367 0.905922277898314 0.955110326566749 GZMM/GZMA 2 GO:0003774 cytoskeletal motor activity 1/377 114/18367 0.906676740026853 0.955110326566749 KIF2A 1 GO:0017171 serine hydrolase activity 2/377 195/18367 0.912020107362318 0.956676210315071 GZMM/GZMA 2 GO:0016829 lyase activity 2/377 196/18367 0.91348572744403 0.956676210315071 RPS3/ALOX5AP 2 GO:0016758 hexosyltransferase activity 2/377 197/18367 0.914928462005562 0.956676210315071 MGAT4A/OGT 2 GO:0004197 cysteine-type endopeptidase activity 1/377 119/18367 0.915925296691102 0.956676210315071 SENP7 1 GO:0016757 glycosyltransferase activity 3/377 270/18367 0.917928006205017 0.956741029723199 MGAT4A/OGT/APRT 3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/377 125/18367 0.925824700906776 0.96293581760979 GLS 1 GO:0042826 histone deacetylase binding 1/377 127/18367 0.928859003857773 0.964057871372383 LEF1 1 GO:0004519 endonuclease activity 1/377 129/18367 0.931769497780534 0.965046979844124 RPS3 1 GO:0043177 organic acid binding 1/377 135/18367 0.939807499964514 0.971331441263114 ALOX5AP 1 GO:0004175 endopeptidase activity 5/377 430/18367 0.942786164759408 0.972035847182939 GZMM/GZMA/PSMB8/PSMB9/SENP7 5 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/377 222/18367 0.944432395133119 0.972035847182939 EPC1/KAT6A 2 GO:0070851 growth factor receptor binding 1/377 141/18367 0.946900786313873 0.972546015943207 FYN 1 GO:0005319 lipid transporter activity 1/377 154/18367 0.959538533276206 0.981107500635576 OSBPL8 1 GO:0016853 isomerase activity 1/377 158/18367 0.962786330036847 0.981107500635576 FKBP5 1 GO:0008083 growth factor activity 1/377 162/18367 0.965774065562754 0.981107500635576 GMFG 1 GO:0016746 acyltransferase activity 2/377 250/18367 0.965890616054842 0.981107500635576 EPC1/KAT6A 2 GO:0046943 carboxylic acid transmembrane transporter activity 1/377 163/18367 0.966482836630199 0.981107500635576 SERINC5 1 GO:0005342 organic acid transmembrane transporter activity 1/377 164/18367 0.967176968172191 0.981107500635576 SERINC5 1 GO:0031406 carboxylic acid binding 1/377 176/18367 0.974468485659514 0.986474257556756 ALOX5AP 1 GO:0008509 anion transmembrane transporter activity 2/377 314/18367 0.989199234356134 0.995960715635416 SLC2A3/SERINC5 2 GO:0048018 receptor ligand activity 4/377 487/18367 0.990841816558592 0.995960715635416 LTB/IL32/GMFG/IL16 4 GO:0046982 protein heterodimerization activity 2/377 328/18367 0.991645460426765 0.995960715635416 CD3E/BCL2 2 GO:0030546 signaling receptor activator activity 4/377 495/18367 0.991920307052716 0.995960715635416 LTB/IL32/GMFG/IL16 4 GO:0015267 channel activity 1/377 480/18367 0.999958444977026 0.999959320822258 BCL2 1 GO:0022803 passive transmembrane transporter activity 1/377 481/18367 0.999959320822258 0.999959320822258 BCL2 1