ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	115/2602	489/18639	0.235173824130879	1.68462909607051	6.34944658540728e-09	4.61642466877602e-06
GO:0060589	nucleoside-triphosphatase regulator activity	115/2602	490/18639	0.23469387755102	1.6811910775071	7.17950959374187e-09	4.61642466877602e-06
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	85/2602	349/18639	0.243553008595989	1.74465200892415	1.19423479126669e-07	5.11928647189653e-05
GO:0051059	NF-kappaB binding	17/2602	32/18639	0.53125	3.8055221944658	1.9216410661283e-07	6.17807602760248e-05
GO:0140297	DNA-binding transcription factor binding	109/2602	488/18639	0.223360655737705	1.60000740288051	2.66443197672433e-07	6.85291904413498e-05
GO:0140097	catalytic activity, acting on DNA	80/2602	336/18639	0.238095238095238	1.70555616558691	7.44341189480492e-07	0.00013609913747141
GO:0008094	ATP-dependent activity, acting on DNA	56/2602	210/18639	0.266666666666667	1.91022290545734	8.22971593505465e-07	0.00013609913747141
GO:0003735	structural constituent of ribosome	49/2602	175/18639	0.28	2.00573405073021	8.46650932948117e-07	0.00013609913747141
GO:0004674	protein serine/threonine kinase activity	96/2602	433/18639	0.221709006928406	1.58817608767816	1.91108242346824e-06	0.000259119623127418
GO:0004386	helicase activity	44/2602	155/18639	0.283870967741935	2.0334630929062	2.01492708497215e-06	0.000259119623127418
GO:0003713	transcription coactivator activity	63/2602	256/18639	0.24609375	1.7628521930246	3.43911779314363e-06	0.000402064134725701
GO:0003712	transcription coregulator activity	105/2602	495/18639	0.212121212121212	1.51949549297743	5.38611833635893e-06	0.000577212348379799
GO:0032451	demethylase activity	17/2602	40/18639	0.425	3.04441775557264	9.89881598950968e-06	0.000979221335577649
GO:1990841	promoter-specific chromatin binding	23/2602	68/18639	0.338235294117647	2.42289302346611	2.71513664406803e-05	0.0024940469459082
GO:0008135	translation factor activity, RNA binding	26/2602	83/18639	0.313253012048193	2.24393654556736	3.84178104177641e-05	0.00329368694648297
GO:0005096	GTPase activator activity	62/2602	271/18639	0.228782287822878	1.63884437460823	4.556234530808e-05	0.00345267355090278
GO:0140658	ATP-dependent chromatin remodeler activity	41/2602	158/18639	0.259493670886076	1.85884032730422	4.60239044590047e-05	0.00345267355090278
GO:0180051	translation factor activity	26/2602	84/18639	0.30952380952381	2.21722301526298	4.83266904480949e-05	0.00345267355090278
GO:0005112	Notch binding	12/2602	26/18639	0.461538461538462	3.30615502867617	7.65579275266734e-05	0.00505764340692085
GO:0015631	tubulin binding	81/2602	385/18639	0.21038961038961	1.5070914481368	8.22366552357629e-05	0.00505764340692085
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	7/2602	10/18639	0.7	5.01433512682552	8.34505572583086e-05	0.00505764340692085
GO:0032452	histone demethylase activity	13/2602	30/18639	0.433333333333333	3.10411222136818	8.65226710359709e-05	0.00505764340692085
GO:0019843	rRNA binding	21/2602	65/18639	0.323076923076923	2.31430852007332	0.000127063475268638	0.00668970143681914
GO:0005085	guanyl-nucleotide exchange factor activity	53/2602	230/18639	0.230434782608696	1.65068174982455	0.000128870144303022	0.00668970143681914
GO:0140457	protein demethylase activity	13/2602	31/18639	0.419354838709677	3.00397956906598	0.000130048628242985	0.00668970143681914
GO:0000510	H3-H4 histone complex chaperone activity	38/2602	151/18639	0.251655629139073	1.80269380150776	0.000171210368691957	0.00759229428061576
GO:0140584	chromatin extrusion motor activity	38/2602	151/18639	0.251655629139073	1.80269380150776	0.000171210368691957	0.00759229428061576
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	38/2602	151/18639	0.251655629139073	1.80269380150776	0.000171210368691957	0.00759229428061576
GO:0140849	ATP-dependent H2AZ histone chaperone activity	38/2602	151/18639	0.251655629139073	1.80269380150776	0.000171210368691957	0.00759229428061576
GO:0140296	general transcription initiation factor binding	18/2602	53/18639	0.339622641509434	2.43283105883718	0.000186711139863512	0.00786046731613636
GO:0015616	DNA translocase activity	38/2602	152/18639	0.25	1.79083397386626	0.000198035778494994	0.00786046731613636
GO:0140674	ATP-dependent histone chaperone activity	38/2602	152/18639	0.25	1.79083397386626	0.000198035778494994	0.00786046731613636
GO:0048407	platelet-derived growth factor binding	7/2602	11/18639	0.636363636363636	4.55848647893229	0.000201707170631804	0.00786046731613636
GO:0061775	cohesin loader activity	38/2602	153/18639	0.248366013071895	1.77912917665144	0.000228574479977187	0.00857555462533721
GO:0003724	RNA helicase activity	23/2602	77/18639	0.298701298701299	2.13969773500903	0.000233393788403423	0.00857555462533721
GO:0140098	catalytic activity, acting on RNA	79/2602	387/18639	0.204134366925065	1.46228303809234	0.000274890472229786	0.00975254436188452
GO:0016887	ATP hydrolysis activity	84/2602	417/18639	0.201438848920863	1.44297413721598	0.000282107398197683	0.00975254436188452
GO:0003689	DNA clamp loader activity	39/2602	160/18639	0.24375	1.7460631245196	0.000288177827178547	0.00975254436188452
GO:0031267	small GTPase binding	61/2602	283/18639	0.215547703180212	1.54404059937585	0.00030123892416601	0.00991068707773928
GO:0140104	molecular carrier activity	55/2602	249/18639	0.220883534136546	1.5822629487975	0.000308263983755499	0.00991068707773928
GO:0140597	protein carrier chaperone	44/2602	188/18639	0.234042553191489	1.67652542234288	0.000322239192212462	0.0101073073459811
GO:0008186	ATP-dependent activity, acting on RNA	23/2602	79/18639	0.291139240506329	2.08552817209741	0.000353093109239763	0.0108113747257699
GO:0106310	protein serine kinase activity	74/2602	361/18639	0.204986149584488	1.46838464339172	0.00037096753935831	0.0110945175724369
GO:0001221	transcription coregulator binding	30/2602	115/18639	0.260869565217391	1.86869632055609	0.000412470371557994	0.012055384041445
GO:0140713	histone chaperone activity	39/2602	164/18639	0.23780487804878	1.70347621904351	0.000489440022959198	0.0139871082116784
GO:0031625	ubiquitin protein ligase binding	63/2602	302/18639	0.208609271523179	1.4943382828288	0.000606659331793034	0.0169600847975183
GO:0051020	GTPase binding	65/2602	315/18639	0.206349206349206	1.47814867684199	0.000679354655305835	0.0185882997175171
GO:0044389	ubiquitin-like protein ligase binding	66/2602	322/18639	0.204968944099379	1.46826139472265	0.000747749767121282	0.019920443357281
GO:0045296	cadherin binding	68/2602	334/18639	0.203592814371257	1.45840371524438	0.000759021558714438	0.019920443357281
GO:0005201	extracellular matrix structural constituent	39/2602	168/18639	0.232142857142857	1.66291726144724	0.000806993009337826	0.0207558602001689
GO:0141052	histone H3 demethylase activity	11/2602	28/18639	0.392857142857143	2.8141676732184	0.000831841549146262	0.0208118781601023
GO:1901981	phosphatidylinositol phosphate binding	42/2602	185/18639	0.227027027027027	1.62627085194341	0.000841537841621554	0.0208118781601023
GO:0002039	p53 binding	20/2602	69/18639	0.289855072463768	2.07632924506233	0.00088847035893394	0.0215579788979066
GO:0046332	SMAD binding	22/2602	79/18639	0.278481012658228	1.99485303418013	0.00091346377220584	0.0217539705751243
GO:0043021	ribonucleoprotein complex binding	40/2602	177/18639	0.225988700564972	1.61883297072656	0.00120942624977169	0.02827858467648
GO:0042393	histone binding	52/2602	247/18639	0.210526315789474	1.50807071483474	0.00140183140083557	0.0321920568120454
GO:0035091	phosphatidylinositol binding	58/2602	284/18639	0.204225352112676	1.46293479555272	0.00164657068193273	0.0367931825913401
GO:0000900	mRNA regulatory element binding translation repressor activity	8/2602	18/18639	0.444444444444444	3.1837048424289	0.00168802315154671	0.0367931825913401
GO:0003746	translation elongation factor activity	8/2602	18/18639	0.444444444444444	3.1837048424289	0.00168802315154671	0.0367931825913401
GO:0019838	growth factor binding	32/2602	136/18639	0.235294117647059	1.68549079893295	0.00179799100352777	0.0385369405089453
GO:0001223	transcription coactivator binding	14/2602	44/18639	0.318181818181818	2.27924323946614	0.00193491469495512	0.0407918081592177
GO:0019207	kinase regulator activity	58/2602	287/18639	0.202090592334495	1.44764279420548	0.00211726815609986	0.0439162394958778
GO:0004860	protein kinase inhibitor activity	22/2602	84/18639	0.261904761904762	1.8761117821456	0.00217711674576078	0.0444408275404503
GO:0071949	FAD binding	13/2602	40/18639	0.325	2.32808416602613	0.00224404528153307	0.0446018343975324
GO:0045309	protein phosphorylated amino acid binding	17/2602	59/18639	0.288135593220339	2.06401203767636	0.00225436954575397	0.0446018343975324
GO:0004519	endonuclease activity	30/2602	127/18639	0.236220472440945	1.69212658947993	0.00230192163325033	0.0448525942478776
GO:0010181	FMN binding	7/2602	15/18639	0.466666666666667	3.34289008455035	0.0023551596833057	0.0452050052646437
GO:0140030	modification-dependent protein binding	38/2602	173/18639	0.219653179190751	1.57344950305012	0.00268978843345412	0.0508686459620882
GO:0097110	scaffold protein binding	19/2602	70/18639	0.271428571428571	1.94433402876908	0.00273645624028798	0.0510011989131933
GO:0019887	protein kinase regulator activity	52/2602	255/18639	0.203921568627451	1.46075869240855	0.00286086233016929	0.0525581279513959
GO:0035591	signaling adaptor activity	30/2602	129/18639	0.232558139534884	1.6658920687128	0.00295981119933601	0.0534439289525473
GO:0050660	flavin adenine dinucleotide binding	22/2602	86/18639	0.255813953488372	1.83248127558408	0.00299219508910063	0.0534439289525473
GO:0004520	DNA endonuclease activity	13/2602	42/18639	0.30952380952381	2.21722301526298	0.00363682597816731	0.0640679206564817
GO:0008017	microtubule binding	55/2602	276/18639	0.199275362318841	1.42747635598035	0.00370223000079946	0.0643387537976771
GO:0001784	phosphotyrosine residue binding	14/2602	47/18639	0.297872340425532	2.13375962843639	0.00383385450614639	0.0657378252653902
GO:0001217	DNA-binding transcription repressor activity	55/2602	278/18639	0.197841726618705	1.41720674190855	0.00433143836989774	0.0732924966274802
GO:0016879	ligase activity, forming carbon-nitrogen bonds	14/2602	48/18639	0.291666666666667	2.08930630284397	0.00472986511621912	0.0789948901228285
GO:0017025	TBP-class protein binding	9/2602	25/18639	0.36	2.57880092236741	0.0049049916477173	0.0808694776790313
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	53/2602	268/18639	0.197761194029851	1.41662985992405	0.00507083735895695	0.0825455296660587
GO:0003684	damaged DNA binding	19/2602	74/18639	0.256756756756757	1.83923489207886	0.00533144109665569	0.0857029156287402
GO:0019210	kinase inhibitor activity	22/2602	90/18639	0.244444444444444	1.7510376633359	0.00540133440216666	0.0857545190269916
GO:0043022	ribosome binding	26/2602	112/18639	0.232142857142857	1.66291726144724	0.00554183738464513	0.0869122302030932
GO:0070063	RNA polymerase binding	16/2602	59/18639	0.271186440677966	1.94259956487187	0.00576915532053495	0.0883501275956997
GO:0001968	fibronectin binding	10/2602	30/18639	0.333333333333333	2.38777863182168	0.00577092590827276	0.0883501275956997
GO:0052742	phosphatidylinositol kinase activity	9/2602	26/18639	0.346153846153846	2.47961627150712	0.00658690731831747	0.0996560330747796
GO:0061791	GTPase motor activity	12/2602	40/18639	0.3	2.14900076863951	0.00675543749937213	0.0998562370596846
GO:1990606	membrane scission GTPase motor activity	12/2602	40/18639	0.3	2.14900076863951	0.00675543749937213	0.0998562370596846
GO:0004715	non-membrane spanning protein tyrosine kinase activity	13/2602	45/18639	0.288888888888889	2.06940814757879	0.00696026670427307	0.101714806610172
GO:0070513	death domain binding	5/2602	10/18639	0.5	3.58166794773251	0.0072189333193628	0.103450806978263
GO:0140034	methylation-dependent protein binding	19/2602	76/18639	0.25	1.79083397386626	0.00723994761123144	0.103450806978263
GO:0016881	acid-amino acid ligase activity	8/2602	22/18639	0.363636363636364	2.60484941653274	0.00736417470250583	0.104069545795852
GO:0061630	ubiquitin protein ligase activity	66/2602	353/18639	0.186968838526912	1.33932059235323	0.0074950471848277	0.104767724779222
GO:0019902	phosphatase binding	39/2602	190/18639	0.205263157894737	1.47036894696387	0.0079610025195662	0.110084400431851
GO:0051219	phosphoprotein binding	22/2602	93/18639	0.236559139784946	1.69455257742183	0.00810961712254016	0.110946464038156
GO:0001727	lipid kinase activity	12/2602	41/18639	0.292682926829268	2.09658611574586	0.00836226199713826	0.112019468003331
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	12/2602	41/18639	0.292682926829268	2.09658611574586	0.00836226199713826	0.112019468003331
GO:0016830	carbon-carbon lyase activity	14/2602	51/18639	0.274509803921569	1.96640593208844	0.00846847172531681	0.112272728234613
GO:0042826	histone deacetylase binding	28/2602	127/18639	0.220472440944882	1.57931815018127	0.00860450549602043	0.112724961976788
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	9/2602	27/18639	0.333333333333333	2.38777863182168	0.00867789365140122	0.112724961976788
GO:0004518	nuclease activity	42/2602	209/18639	0.200956937799043	1.43952204597862	0.00881929636187224	0.113416151213677
GO:0140101	catalytic activity, acting on a tRNA	30/2602	139/18639	0.215827338129496	1.54604371844569	0.00913897316100671	0.116363559257967
GO:0030515	snoRNA binding	10/2602	32/18639	0.3125	2.23854246733282	0.00953524578117561	0.120218883084234
GO:0019208	phosphatase regulator activity	26/2602	117/18639	0.222222222222222	1.59185242121445	0.00997566715603345	0.124550562744262
GO:0030145	manganese ion binding	17/2602	68/18639	0.25	1.79083397386626	0.0107156830453521	0.132503542272335
GO:0016829	lyase activity	40/2602	200/18639	0.2	1.43266717909301	0.0112409471486156	0.137674838410663
GO:0035173	histone kinase activity	66/2602	360/18639	0.183333333333333	1.31327824750192	0.0115522749519745	0.140040034404563
GO:0034511	U3 snoRNA binding	5/2602	11/18639	0.454545454545455	3.25606177066592	0.0117276328767677	0.140040034404563
GO:0035064	methylated histone binding	18/2602	74/18639	0.243243243243243	1.74243305565366	0.0117607493901189	0.140040034404563
GO:0004536	DNA nuclease activity	16/2602	64/18639	0.25	1.79083397386626	0.013059604464569	0.152922361303933
GO:0031072	heat shock protein binding	28/2602	131/18639	0.213740458015267	1.5310946952139	0.0130804508113784	0.152922361303933
GO:0140996	histone H3 kinase activity	65/2602	357/18639	0.182072829131653	1.30424883250764	0.0140121503909727	0.160100081363164
GO:0005543	phospholipid binding	87/2602	497/18639	0.175050301810865	1.25394411047376	0.0141887639713994	0.160100081363164
GO:0140463	chromatin-protein adaptor activity	14/2602	54/18639	0.259259259259259	1.85716115808353	0.0142249671588492	0.160100081363164
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	9/2602	29/18639	0.310344827586207	2.22310424342018	0.0143168813038599	0.160100081363164
GO:0097472	cyclin-dependent protein kinase activity	9/2602	29/18639	0.310344827586207	2.22310424342018	0.0143168813038599	0.160100081363164
GO:0030020	extracellular matrix structural constituent conferring tensile strength	12/2602	44/18639	0.272727272727273	1.95363706239955	0.0150060662374144	0.165573654600567
GO:0043024	ribosomal small subunit binding	7/2602	20/18639	0.35	2.50716756341276	0.0150638550453082	0.165573654600567
GO:0001098	basal transcription machinery binding	15/2602	60/18639	0.25	1.79083397386626	0.0159381696418547	0.17076564256925
GO:0001099	basal RNA polymerase II transcription machinery binding	15/2602	60/18639	0.25	1.79083397386626	0.0159381696418547	0.17076564256925
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	15/2602	60/18639	0.25	1.79083397386626	0.0159381696418547	0.17076564256925
GO:0061659	ubiquitin-like protein ligase activity	67/2602	372/18639	0.18010752688172	1.29017071235526	0.0160673738342762	0.17076564256925
GO:0004842	ubiquitin-protein transferase activity	79/2602	449/18639	0.175946547884187	1.26036422214195	0.0166677080668466	0.173243242776294
GO:0140327	flippase activity	6/2602	16/18639	0.375	2.68625096079939	0.0168357946877936	0.173243242776294
GO:0140328	floppase activity	6/2602	16/18639	0.375	2.68625096079939	0.0168357946877936	0.173243242776294
GO:0141003	histone H2AX kinase activity	64/2602	354/18639	0.180790960451977	1.29506637658125	0.0169402952259932	0.173243242776294
GO:0042974	nuclear retinoic acid receptor binding	8/2602	25/18639	0.32	2.29226748654881	0.0169740657774596	0.173243242776294
GO:0097371	MDM2/MDM4 family protein binding	5/2602	12/18639	0.416666666666667	2.98472328977709	0.0178249716651687	0.180495382373283
GO:0051721	protein phosphatase 2A binding	9/2602	30/18639	0.3	2.14900076863951	0.0179794336162544	0.180637122113306
GO:0140566	histone reader activity	10/2602	35/18639	0.285714285714286	2.04666739870429	0.0183522154438108	0.182953093494114
GO:0050840	extracellular matrix binding	16/2602	67/18639	0.238805970149254	1.7106473780215	0.0200566581476098	0.198406633675586
GO:0003743	translation initiation factor activity	13/2602	51/18639	0.254901960784314	1.82594836551069	0.0204250619418148	0.200508623337205
GO:0019888	protein phosphatase regulator activity	23/2602	107/18639	0.214953271028037	1.53978248220276	0.0215121653312772	0.208763057996779
GO:0070412	R-SMAD binding	8/2602	26/18639	0.307692307692308	2.20410335245078	0.0215905806481894	0.208763057996779
GO:0005164	tumor necrosis factor receptor binding	9/2602	31/18639	0.290322580645161	2.07967816319952	0.0222778990094886	0.212594782084802
GO:0000993	RNA polymerase II complex binding	10/2602	36/18639	0.277777777777778	1.98981552651806	0.0223174926760873	0.212594782084802
GO:0016504	peptidase activator activity	14/2602	57/18639	0.245614035087719	1.75941583397387	0.0226040052054501	0.213740813928006
GO:0005548	phospholipid transporter activity	16/2602	68/18639	0.235294117647059	1.68549079893295	0.0229308043329198	0.213938502807339
GO:0070402	NADPH binding	6/2602	17/18639	0.352941176470588	2.52823619839942	0.0230084366528252	0.213938502807339
GO:0016922	nuclear receptor binding	28/2602	137/18639	0.204379562043796	1.46403945308774	0.0231239905833749	0.213938502807339
GO:0016874	ligase activity	33/2602	167/18639	0.197604790419162	1.41550948832542	0.0233585978617265	0.214565406072716
GO:0016755	aminoacyltransferase activity	85/2602	496/18639	0.171370967741935	1.22758780466639	0.0248082600027596	0.22626540683368
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/2602	13/18639	0.384615384615385	2.75512919056347	0.0256958317696998	0.231082794796041
GO:0140333	glycerophospholipid flippase activity	5/2602	13/18639	0.384615384615385	2.75512919056347	0.0256958317696998	0.231082794796041
GO:0017124	SH3 domain binding	24/2602	115/18639	0.208695652173913	1.49495705644488	0.0267429932788288	0.23882978719843
GO:0003725	double-stranded RNA binding	17/2602	75/18639	0.226666666666667	1.62368946963874	0.0274792372429444	0.243712407547769
GO:0019787	ubiquitin-like protein transferase activity	82/2602	479/18639	0.171189979123173	1.22629132239694	0.0276988093679979	0.243977183885241
GO:0140693	molecular condensate scaffold activity	12/2602	48/18639	0.25	1.79083397386626	0.0292715037266504	0.256075876139268
GO:0004879	nuclear receptor activity	14/2602	59/18639	0.23728813559322	1.69977461926289	0.0299478527264883	0.260222558150432
GO:0004706	JUN kinase kinase kinase activity	6/2602	18/18639	0.333333333333333	2.38777863182168	0.0305339750940827	0.261777946473269
GO:0008525	phosphatidylcholine transporter activity	6/2602	18/18639	0.333333333333333	2.38777863182168	0.0305339750940827	0.261777946473269
GO:0004712	protein serine/threonine/tyrosine kinase activity	11/2602	43/18639	0.255813953488372	1.83248127558408	0.0307541076028503	0.261919088591162
GO:0071889	14-3-3 protein binding	9/2602	33/18639	0.272727272727273	1.95363706239955	0.0329860082137184	0.274877328954048
GO:0140311	protein sequestering activity	9/2602	33/18639	0.272727272727273	1.95363706239955	0.0329860082137184	0.274877328954048
GO:0046966	nuclear thyroid hormone receptor binding	8/2602	28/18639	0.285714285714286	2.04666739870429	0.0333443727191536	0.274877328954048
GO:0051019	mitogen-activated protein kinase binding	8/2602	28/18639	0.285714285714286	2.04666739870429	0.0333443727191536	0.274877328954048
GO:0097718	disordered domain specific binding	8/2602	28/18639	0.285714285714286	2.04666739870429	0.0333443727191536	0.274877328954048
GO:0001222	transcription corepressor binding	12/2602	49/18639	0.244897959183673	1.75428634174654	0.034001871965974	0.278457004697838
GO:0098531	ligand-modulated transcription factor activity	14/2602	60/18639	0.233333333333333	1.67144504227517	0.0342116693174638	0.278457004697838
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	82/2602	484/18639	0.169421487603306	1.21362302361184	0.0344903414163555	0.278959616738573
GO:0001216	DNA-binding transcription activator activity	83/2602	491/18639	0.169042769857434	1.21091014118859	0.0351958229610879	0.281653976876284
GO:0005545	1-phosphatidylinositol binding	5/2602	14/18639	0.357142857142857	2.55833424838037	0.0354796835897476	0.281653976876284
GO:0002020	protease binding	27/2602	136/18639	0.198529411764706	1.42213286159967	0.0354805165271836	0.281653976876284
GO:0001046	core promoter sequence-specific DNA binding	11/2602	44/18639	0.25	1.79083397386626	0.0360034547246623	0.284051796171262
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	14/2602	61/18639	0.229508196721311	1.64404430387722	0.0388966218621205	0.292296230798049
GO:0032813	tumor necrosis factor receptor superfamily binding	12/2602	50/18639	0.24	1.71920061491161	0.039251735644281	0.292296230798049
GO:0030332	cyclin binding	9/2602	34/18639	0.264705882352941	1.89617714879957	0.0394862626958749	0.292296230798049
GO:0004382	GDP phosphatase activity	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0030957	Tat protein binding	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0043422	protein kinase B binding	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0051864	histone H3K36 demethylase activity	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0070739	protein-glutamic acid ligase activity	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0070740	tubulin-glutamic acid ligase activity	4/2602	10/18639	0.4	2.86533435818601	0.0395486346491917	0.292296230798049
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	8/2602	29/18639	0.275862068965517	1.97609266081794	0.0405929408773608	0.298300125533063
GO:0046915	transition metal ion transmembrane transporter activity	11/2602	45/18639	0.244444444444444	1.7510376633359	0.0418501628195789	0.30565624209853
GO:0032182	ubiquitin-like protein binding	24/2602	120/18639	0.2	1.43266717909301	0.042069327256174	0.30565624209853
GO:0030544	Hsp70 protein binding	12/2602	51/18639	0.235294117647059	1.68549079893295	0.045044558321963	0.324400599308405
GO:0140767	enzyme-substrate adaptor activity	27/2602	139/18639	0.194244604316547	1.39143934660112	0.0451537381619009	0.324400599308405
GO:0010485	histone H4 acetyltransferase activity	9/2602	35/18639	0.257142857142857	1.84200065883386	0.0468018944369742	0.330356368894261
GO:0003678	DNA helicase activity	16/2602	74/18639	0.216216216216216	1.54882938280325	0.0470464573437491	0.330356368894261
GO:0042809	nuclear vitamin D receptor binding	5/2602	15/18639	0.333333333333333	2.38777863182168	0.0472671632010451	0.330356368894261
GO:0050700	CARD domain binding	5/2602	15/18639	0.333333333333333	2.38777863182168	0.0472671632010451	0.330356368894261
GO:0120283	protein serine/threonine kinase binding	5/2602	15/18639	0.333333333333333	2.38777863182168	0.0472671632010451	0.330356368894261
GO:0030291	protein serine/threonine kinase inhibitor activity	11/2602	46/18639	0.239130434782609	1.71297162717642	0.0483198675383557	0.330407475120707
GO:0140857	histone H3T45 kinase activity	44/2602	246/18639	0.178861788617886	1.28124707073358	0.0483841319716171	0.330407475120707
GO:0035925	mRNA 3'-UTR AU-rich region binding	8/2602	30/18639	0.266666666666667	1.91022290545734	0.0488160344268541	0.330407475120707
GO:0043995	histone H4K5 acetyltransferase activity	8/2602	30/18639	0.266666666666667	1.91022290545734	0.0488160344268541	0.330407475120707
GO:0043996	histone H4K8 acetyltransferase activity	8/2602	30/18639	0.266666666666667	1.91022290545734	0.0488160344268541	0.330407475120707
GO:0043997	histone H4K12 acetyltransferase activity	8/2602	30/18639	0.266666666666667	1.91022290545734	0.0488160344268541	0.330407475120707
GO:0061608	nuclear import signal receptor activity	6/2602	20/18639	0.3	2.14900076863951	0.0499744571833155	0.335488214366984
GO:0003707	nuclear steroid receptor activity	7/2602	25/18639	0.28	2.00573405073021	0.0500884425804518	0.335488214366984
GO:0035402	histone H3T11 kinase activity	44/2602	247/18639	0.178137651821862	1.2760598356294	0.0511896186775218	0.341087303726907
GO:0042169	SH2 domain binding	10/2602	41/18639	0.24390243902439	1.74715509645488	0.0516605930580234	0.342451147797
GO:1902936	phosphatidylinositol bisphosphate binding	22/2602	111/18639	0.198198198198198	1.41976026756965	0.0544102515405948	0.346135951615377
GO:0005539	glycosaminoglycan binding	43/2602	242/18639	0.177685950413223	1.27282414671486	0.0552347943071156	0.346135951615377
GO:0061733	protein-lysine-acetyltransferase activity	11/2602	47/18639	0.234042553191489	1.67652542234288	0.0554346985169405	0.346135951615377
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0005114	type II transforming growth factor beta receptor binding	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0016176	superoxide-generating NADPH oxidase activator activity	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0019107	myristoyltransferase activity	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0047676	arachidonate-CoA ligase activity	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0140031	phosphorylation-dependent protein binding	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0180030	inositol phosphate kinase activity	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:1990948	ubiquitin ligase inhibitor activity	4/2602	11/18639	0.363636363636364	2.60484941653274	0.0554463499477198	0.346135951615377
GO:0019209	kinase activator activity	28/2602	148/18639	0.189189189189189	1.35522570995284	0.0559624809142906	0.347670292056897
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	43/2602	243/18639	0.176954732510288	1.26758618726336	0.0583692925211066	0.348420585565676
GO:0008013	beta-catenin binding	21/2602	106/18639	0.19811320754717	1.41915145098835	0.0593705963890414	0.348420585565676
GO:0004402	histone acetyltransferase activity	10/2602	42/18639	0.238095238095238	1.70555616558691	0.0596566014080121	0.348420585565676
GO:0035198	miRNA binding	10/2602	42/18639	0.238095238095238	1.70555616558691	0.0596566014080121	0.348420585565676
GO:0043175	RNA polymerase core enzyme binding	10/2602	42/18639	0.238095238095238	1.70555616558691	0.0596566014080121	0.348420585565676
GO:0034237	protein kinase A regulatory subunit binding	7/2602	26/18639	0.269230769230769	1.92859043339443	0.0605876548712854	0.348420585565676
GO:0050681	nuclear androgen receptor binding	7/2602	26/18639	0.269230769230769	1.92859043339443	0.0605876548712854	0.348420585565676
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/2602	16/18639	0.3125	2.23854246733282	0.0610996034343411	0.348420585565676
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/2602	16/18639	0.3125	2.23854246733282	0.0610996034343411	0.348420585565676
GO:0005521	lamin binding	5/2602	16/18639	0.3125	2.23854246733282	0.0610996034343411	0.348420585565676
GO:0015562	efflux transmembrane transporter activity	5/2602	16/18639	0.3125	2.23854246733282	0.0610996034343411	0.348420585565676
GO:0001846	opsonin binding	6/2602	21/18639	0.285714285714286	2.04666739870429	0.0619916993135542	0.348420585565676
GO:0005123	death receptor binding	6/2602	21/18639	0.285714285714286	2.04666739870429	0.0619916993135542	0.348420585565676
GO:0035613	RNA stem-loop binding	6/2602	21/18639	0.285714285714286	2.04666739870429	0.0619916993135542	0.348420585565676
GO:0038024	cargo receptor activity	14/2602	65/18639	0.215384615384615	1.54287234671554	0.0621901448823947	0.348420585565676
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	11/2602	48/18639	0.229166666666667	1.6415978093774	0.0632129456167563	0.348420585565676
GO:0004676	3-phosphoinositide-dependent protein kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0004711	ribosomal protein S6 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0035175	histone H3S10 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0035979	histone H2AXS139 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0044022	histone H3S28 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0044023	histone H4S1 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0044024	histone H2AS1 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0044025	histone H2BS14 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0072354	histone H3T3 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0072371	histone H2AS121 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0072518	Rho-dependent protein serine/threonine kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0140823	histone H2BS36 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0140855	histone H3S57 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0140995	histone H2A kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0140997	histone H4 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0140998	histone H2B kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:1990244	histone H2AT120 kinase activity	43/2602	245/18639	0.175510204081633	1.25723854491835	0.0650240595145895	0.348420585565676
GO:0019903	protein phosphatase binding	27/2602	144/18639	0.1875	1.34312548039969	0.0653674179638809	0.348807051873655
GO:0043425	bHLH transcription factor binding	8/2602	32/18639	0.25	1.79083397386626	0.0683075354254088	0.361285747436627
GO:0008375	acetylglucosaminyltransferase activity	10/2602	43/18639	0.232558139534884	1.6658920687128	0.0684149328641218	0.361285747436627
GO:0004677	DNA-dependent protein kinase activity	43/2602	246/18639	0.17479674796748	1.252127819126	0.0685487732305886	0.361285747436627
GO:0008194	UDP-glycosyltransferase activity	27/2602	145/18639	0.186206896551724	1.33386254605211	0.0700694337485883	0.36676544570875
GO:0005518	collagen binding	15/2602	72/18639	0.208333333333333	1.49236164488855	0.0701588644201808	0.36676544570875
GO:0030295	protein kinase activator activity	26/2602	139/18639	0.18705035971223	1.33990455598626	0.0711447308601519	0.368704835013313
GO:0035403	histone H3T6 kinase activity	43/2602	247/18639	0.174089068825911	1.24705847572873	0.0722078107099112	0.368704835013313
GO:0004364	glutathione transferase activity	7/2602	27/18639	0.259259259259259	1.85716115808353	0.0723337085551053	0.368704835013313
GO:0042162	telomeric DNA binding	9/2602	38/18639	0.236842105263158	1.69657955418909	0.0739098905574091	0.368704835013313
GO:0140313	molecular sequestering activity	12/2602	55/18639	0.218181818181818	1.56290964991964	0.0740207476727973	0.368704835013313
GO:0003697	single-stranded DNA binding	23/2602	121/18639	0.190082644628099	1.36162583136939	0.0741314645444551	0.368704835013313
GO:0000340	RNA 7-methylguanosine cap binding	4/2602	12/18639	0.333333333333333	2.38777863182168	0.0742570390889954	0.368704835013313
GO:0003995	acyl-CoA dehydrogenase activity	4/2602	12/18639	0.333333333333333	2.38777863182168	0.0742570390889954	0.368704835013313
GO:0004875	complement receptor activity	4/2602	12/18639	0.333333333333333	2.38777863182168	0.0742570390889954	0.368704835013313
GO:0005095	GTPase inhibitor activity	4/2602	12/18639	0.333333333333333	2.38777863182168	0.0742570390889954	0.368704835013313
GO:0015132	prostaglandin transmembrane transporter activity	4/2602	12/18639	0.333333333333333	2.38777863182168	0.0742570390889954	0.368704835013313
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/2602	12/18639	0.333333333333333	2.38777863182168	0.0742570390889954	0.368704835013313
GO:1990817	poly(A) RNA polymerase activity	4/2602	12/18639	0.333333333333333	2.38777863182168	0.0742570390889954	0.368704835013313
GO:0008093	cytoskeletal anchor activity	6/2602	22/18639	0.272727272727273	1.95363706239955	0.0755650736073303	0.369996504508956
GO:0046972	histone H4K16 acetyltransferase activity	6/2602	22/18639	0.272727272727273	1.95363706239955	0.0755650736073303	0.369996504508956
GO:0050321	tau-protein kinase activity	6/2602	22/18639	0.272727272727273	1.95363706239955	0.0755650736073303	0.369996504508956
GO:0016836	hydro-lyase activity	13/2602	61/18639	0.213114754098361	1.52661256788599	0.0756680254166838	0.369996504508956
GO:0004679	AMP-activated protein kinase activity	43/2602	248/18639	0.173387096774194	1.24203001413305	0.0760030940465952	0.370227192969399
GO:0017110	nucleoside diphosphate phosphatase activity	5/2602	17/18639	0.294117647058824	2.10686349866618	0.0769709229266394	0.370728864732802
GO:0032183	SUMO binding	5/2602	17/18639	0.294117647058824	2.10686349866618	0.0769709229266394	0.370728864732802
GO:0070403	NAD+ binding	5/2602	17/18639	0.294117647058824	2.10686349866618	0.0769709229266394	0.370728864732802
GO:0016835	carbon-oxygen lyase activity	16/2602	79/18639	0.20253164556962	1.45080220667646	0.0777006279859297	0.372847043245917
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	23/2602	122/18639	0.188524590163934	1.35046496389914	0.0798000429136155	0.380976339204291
GO:0003714	transcription corepressor activity	36/2602	204/18639	0.176470588235294	1.26411809919971	0.0799872562870595	0.380976339204291
GO:0000049	tRNA binding	16/2602	80/18639	0.2	1.43266717909301	0.0851087391923956	0.401958160550221
GO:0036408	histone H3K14 acetyltransferase activity	7/2602	28/18639	0.25	1.79083397386626	0.0853301538337561	0.401958160550221
GO:0051959	dynein light intermediate chain binding	7/2602	28/18639	0.25	1.79083397386626	0.0853301538337561	0.401958160550221
GO:1990782	protein tyrosine kinase binding	22/2602	117/18639	0.188034188034188	1.34695204871992	0.0870649303342794	0.408633213174756
GO:0005178	integrin binding	29/2602	161/18639	0.180124223602484	1.29029031657445	0.087592666811296	0.40961516188846
GO:0005048	signal sequence binding	11/2602	51/18639	0.215686274509804	1.5450332323552	0.0906481132918137	0.416485955677301
GO:0004857	enzyme inhibitor activity	68/2602	416/18639	0.163461538461538	1.17092990598948	0.0906668965231472	0.416485955677301
GO:0016849	phosphorus-oxygen lyase activity	6/2602	23/18639	0.260869565217391	1.86869632055609	0.0906812345176083	0.416485955677301
GO:0017134	fibroblast growth factor binding	6/2602	23/18639	0.260869565217391	1.86869632055609	0.0906812345176083	0.416485955677301
GO:0043274	phospholipase binding	6/2602	23/18639	0.260869565217391	1.86869632055609	0.0906812345176083	0.416485955677301
GO:0008376	acetylgalactosaminyltransferase activity	8/2602	34/18639	0.235294117647059	1.68549079893295	0.0919563199600036	0.420839243660373
GO:0030971	receptor tyrosine kinase binding	16/2602	81/18639	0.197530864197531	1.4149799299684	0.0929559630763668	0.423905562114212
GO:0016854	racemase and epimerase activity	5/2602	18/18639	0.277777777777778	1.98981552651806	0.0948312874776229	0.426470519364278
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/2602	18/18639	0.277777777777778	1.98981552651806	0.0948312874776229	0.426470519364278
GO:0098641	cadherin binding involved in cell-cell adhesion	5/2602	18/18639	0.277777777777778	1.98981552651806	0.0948312874776229	0.426470519364278
GO:0005542	folic acid binding	4/2602	13/18639	0.307692307692308	2.20410335245078	0.095839797897571	0.426470519364278
GO:0031994	insulin-like growth factor I binding	4/2602	13/18639	0.307692307692308	2.20410335245078	0.095839797897571	0.426470519364278
GO:0071714	icosanoid transmembrane transporter activity	4/2602	13/18639	0.307692307692308	2.20410335245078	0.095839797897571	0.426470519364278
GO:0140666	annealing activity	4/2602	13/18639	0.307692307692308	2.20410335245078	0.095839797897571	0.426470519364278
GO:0004177	aminopeptidase activity	9/2602	40/18639	0.225	1.61175057647963	0.096421933866569	0.427581403284164
GO:0010484	histone H3 acetyltransferase activity	7/2602	29/18639	0.241379310344828	1.7290810782157	0.099564721592609	0.438493945096216
GO:0043236	laminin binding	7/2602	29/18639	0.241379310344828	1.7290810782157	0.099564721592609	0.438493945096216
GO:0005080	protein kinase C binding	11/2602	52/18639	0.211538461538462	1.51532105480991	0.101177750505148	0.442566622957893
GO:0030159	signaling receptor complex adaptor activity	11/2602	52/18639	0.211538461538462	1.51532105480991	0.101177750505148	0.442566622957893
GO:0043015	gamma-tubulin binding	8/2602	35/18639	0.228571428571429	1.63733391896343	0.105335409003864	0.459190969420235
GO:0015295	solute:proton symporter activity	6/2602	24/18639	0.25	1.79083397386626	0.107302840331606	0.459971508888153
GO:0035035	histone acetyltransferase binding	6/2602	24/18639	0.25	1.79083397386626	0.107302840331606	0.459971508888153
GO:0043998	histone H2A acetyltransferase activity	6/2602	24/18639	0.25	1.79083397386626	0.107302840331606	0.459971508888153
GO:0048027	mRNA 5'-UTR binding	6/2602	24/18639	0.25	1.79083397386626	0.107302840331606	0.459971508888153
GO:0050431	transforming growth factor beta binding	6/2602	24/18639	0.25	1.79083397386626	0.107302840331606	0.459971508888153
GO:0003727	single-stranded RNA binding	17/2602	89/18639	0.191011235955056	1.36827764295399	0.108626026747034	0.464096579390984
GO:0016758	hexosyltransferase activity	34/2602	197/18639	0.17258883248731	1.23631177891275	0.109551875236542	0.466502356139712
GO:0140299	molecular sensor activity	14/2602	71/18639	0.197183098591549	1.41248876811986	0.112050375750577	0.473910600308275
GO:0004864	protein phosphatase inhibitor activity	11/2602	53/18639	0.207547169811321	1.48673009151161	0.112397148595664	0.473910600308275
GO:0034212	protein N-acetyltransferase activity	11/2602	53/18639	0.207547169811321	1.48673009151161	0.112397148595664	0.473910600308275
GO:0005520	insulin-like growth factor binding	5/2602	19/18639	0.263157894736842	1.88508839354343	0.114592005668948	0.475371997710538
GO:0008381	mechanosensitive monoatomic ion channel activity	5/2602	19/18639	0.263157894736842	1.88508839354343	0.114592005668948	0.475371997710538
GO:0015245	fatty acid transmembrane transporter activity	5/2602	19/18639	0.263157894736842	1.88508839354343	0.114592005668948	0.475371997710538
GO:0043395	heparan sulfate proteoglycan binding	5/2602	19/18639	0.263157894736842	1.88508839354343	0.114592005668948	0.475371997710538
GO:0140036	ubiquitin-modified protein reader activity	5/2602	19/18639	0.263157894736842	1.88508839354343	0.114592005668948	0.475371997710538
GO:0070566	adenylyltransferase activity	7/2602	30/18639	0.233333333333333	1.67144504227517	0.115009974208274	0.475571790456077
GO:0035401	histone H3Y41 kinase activity	21/2602	115/18639	0.182608695652174	1.30808742438927	0.117194289322241	0.481507527375084
GO:0140801	histone H2AXY142 kinase activity	21/2602	115/18639	0.182608695652174	1.30808742438927	0.117194289322241	0.481507527375084
GO:0031490	chromatin DNA binding	23/2602	128/18639	0.1796875	1.28716191871637	0.119853343404428	0.48218507155069
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	23/2602	128/18639	0.1796875	1.28716191871637	0.119853343404428	0.48218507155069
GO:0008174	mRNA methyltransferase activity	4/2602	14/18639	0.285714285714286	2.04666739870429	0.119983843620701	0.48218507155069
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/2602	14/18639	0.285714285714286	2.04666739870429	0.119983843620701	0.48218507155069
GO:0030983	mismatched DNA binding	4/2602	14/18639	0.285714285714286	2.04666739870429	0.119983843620701	0.48218507155069
GO:0032454	histone H3K9 demethylase activity	4/2602	14/18639	0.285714285714286	2.04666739870429	0.119983843620701	0.48218507155069
GO:0046030	inositol trisphosphate phosphatase activity	4/2602	14/18639	0.285714285714286	2.04666739870429	0.119983843620701	0.48218507155069
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	12/2602	60/18639	0.2	1.43266717909301	0.124045730516	0.496081602220304
GO:0051287	NAD binding	11/2602	54/18639	0.203703703703704	1.45919805277991	0.124297924674012	0.496081602220304
GO:0004709	MAP kinase kinase kinase activity	6/2602	25/18639	0.24	1.71920061491161	0.125370544884602	0.496081602220304
GO:0008139	nuclear localization sequence binding	6/2602	25/18639	0.24	1.71920061491161	0.125370544884602	0.496081602220304
GO:0019211	phosphatase activator activity	6/2602	25/18639	0.24	1.71920061491161	0.125370544884602	0.496081602220304
GO:0072341	modified amino acid binding	17/2602	91/18639	0.186813186813187	1.33820560684511	0.126550064832484	0.499212832437347
GO:0016411	acylglycerol O-acyltransferase activity	7/2602	31/18639	0.225806451612903	1.6175274602663	0.131624265370295	0.516063430689634
GO:0072349	modified amino acid transmembrane transporter activity	7/2602	31/18639	0.225806451612903	1.6175274602663	0.131624265370295	0.516063430689634
GO:0043394	proteoglycan binding	8/2602	37/18639	0.216216216216216	1.54882938280325	0.135102144802162	0.52351079144248
GO:0000339	RNA cap binding	5/2602	20/18639	0.25	1.79083397386626	0.136131188497492	0.52351079144248
GO:0001614	purinergic nucleotide receptor activity	5/2602	20/18639	0.25	1.79083397386626	0.136131188497492	0.52351079144248
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/2602	20/18639	0.25	1.79083397386626	0.136131188497492	0.52351079144248
GO:0016502	nucleotide receptor activity	5/2602	20/18639	0.25	1.79083397386626	0.136131188497492	0.52351079144248
GO:0140664	ATP-dependent DNA damage sensor activity	5/2602	20/18639	0.25	1.79083397386626	0.136131188497492	0.52351079144248
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/2602	43/18639	0.209302325581395	1.49930286184152	0.136780424513743	0.52351079144248
GO:0048156	tau protein binding	9/2602	43/18639	0.209302325581395	1.49930286184152	0.136780424513743	0.52351079144248
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	16/2602	86/18639	0.186046511627907	1.33271365497024	0.138797925006254	0.52780875770596
GO:1901681	sulfur compound binding	45/2602	275/18639	0.163636363636364	1.17218223743973	0.142555025433652	0.52780875770596
GO:0031491	nucleosome binding	14/2602	74/18639	0.189189189189189	1.35522570995284	0.143901496673362	0.52780875770596
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	38/2602	229/18639	0.165938864628821	1.18867582544834	0.144702303388079	0.52780875770596
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/2602	26/18639	0.230769230769231	1.65307751433808	0.144805411888598	0.52780875770596
GO:0051139	metal cation:proton antiporter activity	6/2602	26/18639	0.230769230769231	1.65307751433808	0.144805411888598	0.52780875770596
GO:0070006	metalloaminopeptidase activity	6/2602	26/18639	0.230769230769231	1.65307751433808	0.144805411888598	0.52780875770596
GO:0120014	phospholipid transfer activity	6/2602	26/18639	0.230769230769231	1.65307751433808	0.144805411888598	0.52780875770596
GO:0004467	long-chain fatty acid-CoA ligase activity	4/2602	15/18639	0.266666666666667	1.91022290545734	0.146426272864212	0.52780875770596
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/2602	15/18639	0.266666666666667	1.91022290545734	0.146426272864212	0.52780875770596
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/2602	15/18639	0.266666666666667	1.91022290545734	0.146426272864212	0.52780875770596
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/2602	15/18639	0.266666666666667	1.91022290545734	0.146426272864212	0.52780875770596
GO:0140142	nucleocytoplasmic carrier activity	7/2602	32/18639	0.21875	1.56697972713297	0.149352949754864	0.52780875770596
GO:0019212	phosphatase inhibitor activity	11/2602	56/18639	0.196428571428571	1.4070838366092	0.150087838527775	0.52780875770596
GO:0170055	lipid transmembrane transporter activity	11/2602	56/18639	0.196428571428571	1.4070838366092	0.150087838527775	0.52780875770596
GO:0000287	magnesium ion binding	38/2602	230/18639	0.165217391304348	1.18350766968553	0.151113124076509	0.52780875770596
GO:0043531	ADP binding	8/2602	38/18639	0.210526315789474	1.50807071483474	0.151420079267429	0.52780875770596
GO:0043014	alpha-tubulin binding	9/2602	44/18639	0.204545454545455	1.46522779679966	0.151908834103854	0.52780875770596
GO:0043130	ubiquitin binding	18/2602	100/18639	0.18	1.2894004611837	0.15281226636062	0.52780875770596
GO:0001094	TFIID-class transcription factor complex binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0005131	growth hormone receptor binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0005381	iron ion transmembrane transporter activity	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0005522	profilin binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0015203	polyamine transmembrane transporter activity	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0015643	toxic substance binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0031434	mitogen-activated protein kinase kinase binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0031996	thioesterase binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0033204	ribonuclease P RNA binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0035256	G protein-coupled glutamate receptor binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0043295	glutathione binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0045322	unmethylated CpG binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0050815	phosphoserine residue binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0099122	RNA polymerase II C-terminal domain binding	3/2602	10/18639	0.3	2.14900076863951	0.153499592054455	0.52780875770596
GO:0005319	lipid transporter activity	30/2602	178/18639	0.168539325842697	1.20730380260647	0.155951856432106	0.534810899657836
GO:0016410	N-acyltransferase activity	17/2602	94/18639	0.180851063829787	1.29549691726495	0.156460055391574	0.535126678812671
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/2602	21/18639	0.238095238095238	1.70555616558691	0.159299778867472	0.536281454511961
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/2602	21/18639	0.238095238095238	1.70555616558691	0.159299778867472	0.536281454511961
GO:0010314	phosphatidylinositol-5-phosphate binding	5/2602	21/18639	0.238095238095238	1.70555616558691	0.159299778867472	0.536281454511961
GO:0019200	carbohydrate kinase activity	5/2602	21/18639	0.238095238095238	1.70555616558691	0.159299778867472	0.536281454511961
GO:0036122	BMP binding	5/2602	21/18639	0.238095238095238	1.70555616558691	0.159299778867472	0.536281454511961
GO:0072542	protein phosphatase activator activity	5/2602	21/18639	0.238095238095238	1.70555616558691	0.159299778867472	0.536281454511961
GO:0003774	cytoskeletal motor activity	26/2602	153/18639	0.169934640522876	1.21729891034046	0.165366178255619	0.549250008619631
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/2602	27/18639	0.222222222222222	1.59185242121445	0.165511612841024	0.549250008619631
GO:0005385	zinc ion transmembrane transporter activity	6/2602	27/18639	0.222222222222222	1.59185242121445	0.165511612841024	0.549250008619631
GO:0008266	poly(U) RNA binding	6/2602	27/18639	0.222222222222222	1.59185242121445	0.165511612841024	0.549250008619631
GO:0008320	protein transmembrane transporter activity	6/2602	27/18639	0.222222222222222	1.59185242121445	0.165511612841024	0.549250008619631
GO:0004713	protein tyrosine kinase activity	24/2602	140/18639	0.171428571428571	1.22800043922258	0.165714621574197	0.549250008619631
GO:0051539	4 iron, 4 sulfur cluster binding	9/2602	45/18639	0.2	1.43266717909301	0.167820715510867	0.553378051658909
GO:0140303	intramembrane lipid transporter activity	9/2602	45/18639	0.2	1.43266717909301	0.167820715510867	0.553378051658909
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2602	39/18639	0.205128205128205	1.46940223496718	0.168633244576701	0.554635172699839
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/2602	16/18639	0.25	1.79083397386626	0.174868496007502	0.557372782205015
GO:0005024	transforming growth factor beta receptor activity	4/2602	16/18639	0.25	1.79083397386626	0.174868496007502	0.557372782205015
GO:0008142	oxysterol binding	4/2602	16/18639	0.25	1.79083397386626	0.174868496007502	0.557372782205015
GO:0015385	sodium:proton antiporter activity	4/2602	16/18639	0.25	1.79083397386626	0.174868496007502	0.557372782205015
GO:0016722	oxidoreductase activity, acting on metal ions	4/2602	16/18639	0.25	1.79083397386626	0.174868496007502	0.557372782205015
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2602	16/18639	0.25	1.79083397386626	0.174868496007502	0.557372782205015
GO:0017116	single-stranded DNA helicase activity	11/2602	58/18639	0.189655172413793	1.35856370431233	0.178393817453852	0.557372782205015
GO:0061980	regulatory RNA binding	11/2602	58/18639	0.189655172413793	1.35856370431233	0.178393817453852	0.557372782205015
GO:0015297	antiporter activity	23/2602	135/18639	0.17037037037037	1.22042018959775	0.179682055425488	0.557372782205015
GO:0032931	histone H3K56 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0034062	5'-3' RNA polymerase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0043992	histone H3K9 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0043993	histone H3K18 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0043994	histone H3K23 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0043999	histone H2AK5 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0044012	histone H2AK9 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0044014	histone H2BK5 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0044015	histone H2BK12 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0044016	histone H3K4 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0044017	histone H3K27 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0044018	histone H3K36 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0097747	RNA polymerase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0140035	ubiquitin-like protein reader activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0140908	histone H3K122 acetyltransferase activity	5/2602	22/18639	0.227272727272727	1.62803088533296	0.183927633355749	0.557372782205015
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/2602	46/18639	0.195652173913043	1.40152224041707	0.184474257699298	0.557372782205015
GO:0004722	protein serine/threonine phosphatase activity	18/2602	103/18639	0.174757281553398	1.25184510794534	0.184632932348407	0.557372782205015
GO:0016741	transferase activity, transferring one-carbon groups	35/2602	215/18639	0.162790697674419	1.16612444809896	0.185858680664089	0.557372782205015
GO:0015036	disulfide oxidoreductase activity	8/2602	40/18639	0.2	1.43266717909301	0.186686072254233	0.557372782205015
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	8/2602	40/18639	0.2	1.43266717909301	0.186686072254233	0.557372782205015
GO:0030331	nuclear estrogen receptor binding	8/2602	40/18639	0.2	1.43266717909301	0.186686072254233	0.557372782205015
GO:0046875	ephrin receptor binding	6/2602	28/18639	0.214285714285714	1.53500054902822	0.18737928347937	0.557372782205015
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/2602	28/18639	0.214285714285714	1.53500054902822	0.18737928347937	0.557372782205015
GO:0008175	tRNA methyltransferase activity	7/2602	34/18639	0.205882352941176	1.47480444906633	0.187878459328414	0.557372782205015
GO:0015035	protein-disulfide reductase activity	7/2602	34/18639	0.205882352941176	1.47480444906633	0.187878459328414	0.557372782205015
GO:0016831	carboxy-lyase activity	7/2602	34/18639	0.205882352941176	1.47480444906633	0.187878459328414	0.557372782205015
GO:0090482	vitamin transmembrane transporter activity	7/2602	34/18639	0.205882352941176	1.47480444906633	0.187878459328414	0.557372782205015
GO:0120013	lipid transfer activity	12/2602	65/18639	0.184615384615385	1.32246201147047	0.189013925912031	0.557372782205015
GO:0000099	sulfur amino acid transmembrane transporter activity	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0001851	complement component C3b binding	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0004143	ATP-dependent diacylglycerol kinase activity	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0008432	JUN kinase binding	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0008526	phosphatidylinositol transfer activity	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0032404	mismatch repair complex binding	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0035252	UDP-xylosyltransferase activity	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0042285	xylosyltransferase activity	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0097493	structural molecule activity conferring elasticity	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0140537	transcription regulator activator activity	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:1900750	oligopeptide binding	3/2602	11/18639	0.272727272727273	1.95363706239955	0.19026955784448	0.557372782205015
GO:0005544	calcium-dependent phospholipid binding	10/2602	53/18639	0.188679245283019	1.3515728104651	0.197731957311782	0.575301577155999
GO:0016860	intramolecular oxidoreductase activity	10/2602	53/18639	0.188679245283019	1.3515728104651	0.197731957311782	0.575301577155999
GO:0051018	protein kinase A binding	10/2602	53/18639	0.188679245283019	1.3515728104651	0.197731957311782	0.575301577155999
GO:1990518	single-stranded 3'-5' DNA helicase activity	9/2602	47/18639	0.191489361702128	1.37170261828054	0.201822335853619	0.584721376403053
GO:0019955	cytokine binding	24/2602	144/18639	0.166666666666667	1.19388931591084	0.203302235484741	0.584721376403053
GO:0004549	tRNA-specific ribonuclease activity	4/2602	17/18639	0.235294117647059	1.68549079893295	0.204990826186229	0.584721376403053
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/2602	17/18639	0.235294117647059	1.68549079893295	0.204990826186229	0.584721376403053
GO:0015278	intracellularly gated calcium channel activity	4/2602	17/18639	0.235294117647059	1.68549079893295	0.204990826186229	0.584721376403053
GO:0032977	membrane insertase activity	4/2602	17/18639	0.235294117647059	1.68549079893295	0.204990826186229	0.584721376403053
GO:0046965	nuclear retinoid X receptor binding	4/2602	17/18639	0.235294117647059	1.68549079893295	0.204990826186229	0.584721376403053
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/2602	41/18639	0.195121951219512	1.39772407716391	0.205516378020358	0.584721376403053
GO:0140318	protein transporter activity	8/2602	41/18639	0.195121951219512	1.39772407716391	0.205516378020358	0.584721376403053
GO:0140828	metal cation:monoatomic cation antiporter activity	8/2602	41/18639	0.195121951219512	1.39772407716391	0.205516378020358	0.584721376403053
GO:0008171	O-methyltransferase activity	5/2602	23/18639	0.217391304347826	1.55724693379674	0.209829410810789	0.591749748479788
GO:0042171	lysophosphatidic acid acyltransferase activity	5/2602	23/18639	0.217391304347826	1.55724693379674	0.209829410810789	0.591749748479788
GO:0044013	histone H2B acetyltransferase activity	5/2602	23/18639	0.217391304347826	1.55724693379674	0.209829410810789	0.591749748479788
GO:0071617	lysophospholipid acyltransferase activity	5/2602	23/18639	0.217391304347826	1.55724693379674	0.209829410810789	0.591749748479788
GO:0099604	ligand-gated calcium channel activity	6/2602	29/18639	0.206896551724138	1.48206949561345	0.210287430058525	0.591749748479788
GO:0043539	protein serine/threonine kinase activator activity	13/2602	73/18639	0.178082191780822	1.27566255672665	0.212521902192811	0.596731803973701
GO:0015485	cholesterol binding	10/2602	54/18639	0.185185185185185	1.32654368434538	0.214421510184002	0.599447961079622
GO:0050661	NADP binding	10/2602	54/18639	0.185185185185185	1.32654368434538	0.214421510184002	0.599447961079622
GO:0008201	heparin binding	28/2602	172/18639	0.162790697674419	1.16612444809896	0.217134510978484	0.605715794182928
GO:0032266	phosphatidylinositol-3-phosphate binding	9/2602	48/18639	0.1875	1.34312548039969	0.219813172017473	0.610539393551772
GO:0043138	3'-5' DNA helicase activity	9/2602	48/18639	0.1875	1.34312548039969	0.219813172017473	0.610539393551772
GO:0051213	dioxygenase activity	16/2602	93/18639	0.172043010752688	1.23240187448861	0.220433616958368	0.610943171138926
GO:0016757	glycosyltransferase activity	42/2602	267/18639	0.157303370786517	1.1268168824327	0.223356016497009	0.617711477882051
GO:0004526	ribonuclease P activity	3/2602	12/18639	0.25	1.79083397386626	0.228940397429642	0.622204317970969
GO:0004859	phospholipase inhibitor activity	3/2602	12/18639	0.25	1.79083397386626	0.228940397429642	0.622204317970969
GO:0005078	MAP-kinase scaffold activity	3/2602	12/18639	0.25	1.79083397386626	0.228940397429642	0.622204317970969
GO:0034452	dynactin binding	3/2602	12/18639	0.25	1.79083397386626	0.228940397429642	0.622204317970969
GO:0035251	UDP-glucosyltransferase activity	3/2602	12/18639	0.25	1.79083397386626	0.228940397429642	0.622204317970969
GO:0097677	STAT family protein binding	3/2602	12/18639	0.25	1.79083397386626	0.228940397429642	0.622204317970969
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/2602	12/18639	0.25	1.79083397386626	0.228940397429642	0.622204317970969
GO:0016853	isomerase activity	29/2602	180/18639	0.161111111111111	1.15409300538048	0.229416378438176	0.622204317970969
GO:0044390	ubiquitin-like protein conjugating enzyme binding	7/2602	36/18639	0.194444444444444	1.39287086856264	0.229945518313459	0.622204317970969
GO:0055106	ubiquitin-protein transferase regulator activity	7/2602	36/18639	0.194444444444444	1.39287086856264	0.229945518313459	0.622204317970969
GO:0005516	calmodulin binding	33/2602	207/18639	0.159420289855072	1.14198108478428	0.230302686900608	0.622204317970969
GO:0008374	O-acyltransferase activity	10/2602	55/18639	0.181818181818182	1.30242470826637	0.231655797130599	0.62277663028005
GO:0008187	poly-pyrimidine tract binding	6/2602	30/18639	0.2	1.43266717909301	0.234106794021088	0.62277663028005
GO:0016769	transferase activity, transferring nitrogenous groups	6/2602	30/18639	0.2	1.43266717909301	0.234106794021088	0.62277663028005
GO:0032934	sterol binding	12/2602	68/18639	0.176470588235294	1.26411809919971	0.234229980595042	0.62277663028005
GO:0005525	GTP binding	58/2602	378/18639	0.153439153439153	1.09913619560045	0.236381021711937	0.62277663028005
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/2602	18/18639	0.222222222222222	1.59185242121445	0.236464980102973	0.62277663028005
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/2602	18/18639	0.222222222222222	1.59185242121445	0.236464980102973	0.62277663028005
GO:0008409	5'-3' exonuclease activity	4/2602	18/18639	0.222222222222222	1.59185242121445	0.236464980102973	0.62277663028005
GO:0030228	lipoprotein particle receptor activity	4/2602	18/18639	0.222222222222222	1.59185242121445	0.236464980102973	0.62277663028005
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/2602	24/18639	0.208333333333333	1.49236164488855	0.236810087252678	0.62277663028005
GO:0004622	lysophospholipase activity	5/2602	24/18639	0.208333333333333	1.49236164488855	0.236810087252678	0.62277663028005
GO:0005540	hyaluronic acid binding	5/2602	24/18639	0.208333333333333	1.49236164488855	0.236810087252678	0.62277663028005
GO:0140612	DNA damage sensor activity	5/2602	24/18639	0.208333333333333	1.49236164488855	0.236810087252678	0.62277663028005
GO:0051087	protein-folding chaperone binding	22/2602	134/18639	0.164179104477612	1.17607007238978	0.237587564372378	0.623546138332404
GO:0016763	pentosyltransferase activity	9/2602	49/18639	0.183673469387755	1.3157147563099	0.238391025620786	0.624380568122874
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	29/2602	181/18639	0.160220994475138	1.14771680093086	0.238928320215439	0.624515893896453
GO:0015179	L-amino acid transmembrane transporter activity	11/2602	62/18639	0.17741935483871	1.27091443306638	0.241637674458706	0.630316530129607
GO:0003924	GTPase activity	51/2602	331/18639	0.154078549848943	1.10371640685413	0.243000398170474	0.632588081067265
GO:0019001	guanyl nucleotide binding	61/2602	400/18639	0.1525	1.09240872405842	0.24552068442572	0.636571774539267
GO:0032561	guanyl ribonucleotide binding	61/2602	400/18639	0.1525	1.09240872405842	0.24552068442572	0.636571774539267
GO:0005507	copper ion binding	11/2602	63/18639	0.174603174603175	1.25074118809707	0.258622460679724	0.66009211789758
GO:0070273	phosphatidylinositol-4-phosphate binding	6/2602	31/18639	0.193548387096774	1.38645210879968	0.258702600897278	0.66009211789758
GO:0070325	lipoprotein particle receptor binding	6/2602	31/18639	0.193548387096774	1.38645210879968	0.258702600897278	0.66009211789758
GO:0001848	complement binding	5/2602	25/18639	0.2	1.43266717909301	0.264669972844697	0.66009211789758
GO:0008483	transaminase activity	5/2602	25/18639	0.2	1.43266717909301	0.264669972844697	0.66009211789758
GO:0015645	fatty acid ligase activity	5/2602	25/18639	0.2	1.43266717909301	0.264669972844697	0.66009211789758
GO:0017056	structural constituent of nuclear pore	5/2602	25/18639	0.2	1.43266717909301	0.264669972844697	0.66009211789758
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	5/2602	25/18639	0.2	1.43266717909301	0.264669972844697	0.66009211789758
GO:0120515	fatty acid-CoA ligase activity	5/2602	25/18639	0.2	1.43266717909301	0.264669972844697	0.66009211789758
GO:0008168	methyltransferase activity	32/2602	204/18639	0.156862745098039	1.12366053262196	0.264807653038726	0.66009211789758
GO:0019205	nucleobase-containing compound kinase activity	8/2602	44/18639	0.181818181818182	1.30242470826637	0.265972610034232	0.66009211789758
GO:0004535	poly(A)-specific ribonuclease activity	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0005172	vascular endothelial growth factor receptor binding	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0009982	pseudouridine synthase activity	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0017154	semaphorin receptor activity	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0031432	titin binding	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0035325	Toll-like receptor binding	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0035673	oligopeptide transmembrane transporter activity	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0046974	histone H3K9 methyltransferase activity	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0070123	transforming growth factor beta receptor activity, type III	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0097157	pre-mRNA intronic binding	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0140852	histone ubiquitin ligase activity	3/2602	13/18639	0.230769230769231	1.65307751433808	0.268870577289264	0.66009211789758
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/2602	19/18639	0.210526315789474	1.50807071483474	0.268964439952046	0.66009211789758
GO:0042577	lipid phosphatase activity	4/2602	19/18639	0.210526315789474	1.50807071483474	0.268964439952046	0.66009211789758
GO:0046527	glucosyltransferase activity	4/2602	19/18639	0.210526315789474	1.50807071483474	0.268964439952046	0.66009211789758
GO:0097001	ceramide binding	4/2602	19/18639	0.210526315789474	1.50807071483474	0.268964439952046	0.66009211789758
GO:1990380	K48-linked deubiquitinase activity	4/2602	19/18639	0.210526315789474	1.50807071483474	0.268964439952046	0.66009211789758
GO:0022884	macromolecule transmembrane transporter activity	6/2602	32/18639	0.1875	1.34312548039969	0.283937135776297	0.6941885106622
GO:0031369	translation initiation factor binding	6/2602	32/18639	0.1875	1.34312548039969	0.283937135776297	0.6941885106622
GO:0141110	transporter inhibitor activity	8/2602	45/18639	0.177777777777778	1.27348193697156	0.287194641282527	0.700820320093606
GO:0050750	low-density lipoprotein particle receptor binding	5/2602	26/18639	0.192307692307692	1.37756459528174	0.293209154024721	0.714141992567786
GO:0016004	phospholipase activator activity	4/2602	20/18639	0.2	1.43266717909301	0.302172752815685	0.730440150603329
GO:0016505	peptidase activator activity involved in apoptotic process	4/2602	20/18639	0.2	1.43266717909301	0.302172752815685	0.730440150603329
GO:0030742	GTP-dependent protein binding	4/2602	20/18639	0.2	1.43266717909301	0.302172752815685	0.730440150603329
GO:0052745	inositol phosphate phosphatase activity	4/2602	20/18639	0.2	1.43266717909301	0.302172752815685	0.730440150603329
GO:0030276	clathrin binding	8/2602	46/18639	0.173913043478261	1.2457975470374	0.308819985194786	0.732653129130161
GO:0005161	platelet-derived growth factor receptor binding	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0008195	phosphatidate phosphatase activity	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0015386	potassium:proton antiporter activity	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0016530	metallochaperone activity	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0034236	protein kinase A catalytic subunit binding	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0042043	neurexin family protein binding	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0070742	C2H2 zinc finger domain binding	3/2602	14/18639	0.214285714285714	1.53500054902822	0.309476050107962	0.732653129130161
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/2602	33/18639	0.181818181818182	1.30242470826637	0.309672102931897	0.732653129130161
GO:0046943	carboxylic acid transmembrane transporter activity	29/2602	188/18639	0.154255319148936	1.10498266472599	0.309924807345884	0.732653129130161
GO:0004521	RNA endonuclease activity	12/2602	73/18639	0.164383561643836	1.17753466774768	0.317351852413479	0.748833912300429
GO:0005342	organic acid transmembrane transporter activity	29/2602	189/18639	0.153439153439153	1.09913619560045	0.320604131532682	0.750705580984732
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/2602	40/18639	0.175	1.25358378170638	0.321647481481262	0.750705580984732
GO:0001671	ATPase activator activity	5/2602	27/18639	0.185185185185185	1.32654368434538	0.322231322475561	0.750705580984732
GO:0005044	scavenger receptor activity	5/2602	27/18639	0.185185185185185	1.32654368434538	0.322231322475561	0.750705580984732
GO:0016405	CoA-ligase activity	5/2602	27/18639	0.185185185185185	1.32654368434538	0.322231322475561	0.750705580984732
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/2602	27/18639	0.185185185185185	1.32654368434538	0.322231322475561	0.750705580984732
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	5/2602	27/18639	0.185185185185185	1.32654368434538	0.322231322475561	0.750705580984732
GO:0008173	RNA methyltransferase activity	11/2602	67/18639	0.164179104477612	1.17607007238978	0.330007583016476	0.765050237681297
GO:0043495	protein-membrane adaptor activity	8/2602	47/18639	0.170212765957447	1.21929121624937	0.330768220957077	0.765050237681297
GO:0061749	forked DNA-dependent helicase activity	8/2602	47/18639	0.170212765957447	1.21929121624937	0.330768220957077	0.765050237681297
GO:0140359	ABC-type transporter activity	8/2602	47/18639	0.170212765957447	1.21929121624937	0.330768220957077	0.765050237681297
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/2602	34/18639	0.176470588235294	1.26411809919971	0.335770740846929	0.771117573534256
GO:0052866	phosphatidylinositol phosphate phosphatase activity	6/2602	34/18639	0.176470588235294	1.26411809919971	0.335770740846929	0.771117573534256
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/2602	21/18639	0.19047619047619	1.36444493246953	0.335789923156441	0.771117573534256
GO:0009975	cyclase activity	4/2602	21/18639	0.19047619047619	1.36444493246953	0.335789923156441	0.771117573534256
GO:0001618	virus receptor activity	13/2602	81/18639	0.160493827160494	1.14967119309933	0.33889156718422	0.77685303992675
GO:0003777	microtubule motor activity	11/2602	68/18639	0.161764705882353	1.1587749242664	0.348490979974999	0.792969548983638
GO:0000774	adenyl-nucleotide exchange factor activity	3/2602	15/18639	0.2	1.43266717909301	0.350238494418901	0.792969548983638
GO:0005041	low-density lipoprotein particle receptor activity	3/2602	15/18639	0.2	1.43266717909301	0.350238494418901	0.792969548983638
GO:0016846	carbon-sulfur lyase activity	3/2602	15/18639	0.2	1.43266717909301	0.350238494418901	0.792969548983638
GO:0061578	K63-linked deubiquitinase activity	3/2602	15/18639	0.2	1.43266717909301	0.350238494418901	0.792969548983638
GO:0141050	histone H3K deacetylase activity	3/2602	15/18639	0.2	1.43266717909301	0.350238494418901	0.792969548983638
GO:0141051	histone H4K deacetylase activity	3/2602	15/18639	0.2	1.43266717909301	0.350238494418901	0.792969548983638
GO:0009378	four-way junction helicase activity	8/2602	48/18639	0.166666666666667	1.19388931591084	0.352959230744997	0.796325562698363
GO:0036121	double-stranded DNA helicase activity	8/2602	48/18639	0.166666666666667	1.19388931591084	0.352959230744997	0.796325562698363
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	13/2602	82/18639	0.158536585365854	1.13565081269568	0.355805207640574	0.799939680114996
GO:0140272	exogenous protein binding	13/2602	82/18639	0.158536585365854	1.13565081269568	0.355805207640574	0.799939680114996
GO:0004896	cytokine receptor activity	15/2602	96/18639	0.15625	1.11927123366641	0.361106728107906	0.810441976172368
GO:0004222	metalloendopeptidase activity	17/2602	110/18639	0.154545454545455	1.10706100202641	0.365062536553411	0.816714039228982
GO:0008080	N-acetyltransferase activity	11/2602	69/18639	0.159420289855072	1.14198108478428	0.367137774913909	0.816714039228982
GO:0004407	histone deacetylase activity	4/2602	22/18639	0.181818181818182	1.30242470826637	0.369537098667707	0.816714039228982
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2602	22/18639	0.181818181818182	1.30242470826637	0.369537098667707	0.816714039228982
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/2602	22/18639	0.181818181818182	1.30242470826637	0.369537098667707	0.816714039228982
GO:0033558	protein lysine deacetylase activity	4/2602	22/18639	0.181818181818182	1.30242470826637	0.369537098667707	0.816714039228982
GO:0140517	protein-RNA adaptor activity	4/2602	22/18639	0.181818181818182	1.30242470826637	0.369537098667707	0.816714039228982
GO:0051879	Hsp90 protein binding	7/2602	42/18639	0.166666666666667	1.19388931591084	0.369656915503859	0.816714039228982
GO:0051536	iron-sulfur cluster binding	12/2602	76/18639	0.157894736842105	1.13105303612606	0.370252165529158	0.816714039228982
GO:0098631	cell adhesion mediator activity	12/2602	76/18639	0.157894736842105	1.13105303612606	0.370252165529158	0.816714039228982
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	13/2602	83/18639	0.156626506024096	1.12196827278368	0.372854080138575	0.821045114825697
GO:0060590	ATPase regulator activity	8/2602	49/18639	0.163265306122449	1.16952422783102	0.375314002476551	0.825049243051017
GO:0030170	pyridoxal phosphate binding	9/2602	56/18639	0.160714285714286	1.15125041177117	0.379682148122327	0.833227376254799
GO:0035250	UDP-galactosyltransferase activity	5/2602	29/18639	0.172413793103448	1.23505791301121	0.380976056682821	0.834642604589622
GO:1901682	sulfur compound transmembrane transporter activity	10/2602	63/18639	0.158730158730159	1.13703744372461	0.383131937501062	0.837418538918764
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	25/2602	167/18639	0.149700598802395	1.07235567297381	0.385660739258573	0.837418538918764
GO:0008028	monocarboxylic acid transmembrane transporter activity	11/2602	70/18639	0.157142857142857	1.12566706928736	0.385902360044555	0.837418538918764
GO:0051540	metal cluster binding	12/2602	77/18639	0.155844155844156	1.11636403565689	0.388155078388804	0.837418538918764
GO:0051117	ATPase binding	13/2602	84/18639	0.154761904761905	1.10861150763149	0.390003694868235	0.837418538918764
GO:0004707	MAP kinase activity	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0022841	potassium ion leak channel activity	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0055102	lipase inhibitor activity	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0070411	I-SMAD binding	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/2602	16/18639	0.1875	1.34312548039969	0.390708494052301	0.837418538918764
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	14/2602	91/18639	0.153846153846154	1.10205167622539	0.391530562834933	0.837784199343967
GO:0008200	ion channel inhibitor activity	7/2602	43/18639	0.162790697674419	1.16612444809896	0.393850310413422	0.841348005301762
GO:0015605	organophosphate ester transmembrane transporter activity	8/2602	50/18639	0.16	1.1461337432744	0.39775535535736	0.848280907113707
GO:0070279	vitamin B6 binding	9/2602	57/18639	0.157894736842105	1.13105303612606	0.400703417919201	0.84889535577848
GO:0140103	catalytic activity, acting on a glycoprotein	4/2602	23/18639	0.173913043478261	1.2457975470374	0.403159769795479	0.84889535577848
GO:0001965	G-protein alpha-subunit binding	5/2602	30/18639	0.166666666666667	1.19388931591084	0.410349909215167	0.84889535577848
GO:0031624	ubiquitin conjugating enzyme binding	5/2602	30/18639	0.166666666666667	1.19388931591084	0.410349909215167	0.84889535577848
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0004955	prostaglandin receptor activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0005337	nucleoside transmembrane transporter activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0008190	eukaryotic initiation factor 4E binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0016427	tRNA (cytidine) methyltransferase activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0031419	cobalamin binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0032356	oxidized DNA binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0032395	MHC class II receptor activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0035374	chondroitin sulfate binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0042975	peroxisome proliferator activated receptor binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0043121	neurotrophin binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0047429	nucleoside triphosphate diphosphatase activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0097177	mitochondrial ribosome binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0140999	histone H3K4 trimethyltransferase activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0141109	transporter activator activity	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:1905394	retromer complex binding	2/2602	10/18639	0.2	1.43266717909301	0.416956396939989	0.84889535577848
GO:0033218	amide binding	36/2602	247/18639	0.145748987854251	1.04404895642405	0.417186520102643	0.84889535577848
GO:0016248	channel inhibitor activity	7/2602	44/18639	0.159090909090909	1.13962161973307	0.418043388863539	0.849295099650096
GO:0008237	metallopeptidase activity	27/2602	184/18639	0.146739130434783	1.0511416803128	0.421406788875677	0.854777808350348
GO:0140375	immune receptor activity	23/2602	156/18639	0.147435897435897	1.05613285638266	0.423013496985807	0.856685601769682
GO:0004540	RNA nuclease activity	18/2602	121/18639	0.148760330578512	1.0656202158543	0.424456580205266	0.857011774606913
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0004659	prenyltransferase activity	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0005092	GDP-dissociation inhibitor activity	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0008429	phosphatidylethanolamine binding	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0016018	cyclosporin A binding	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0045125	bioactive lipid receptor activity	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0045236	CXCR chemokine receptor binding	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:1990226	histone methyltransferase binding	3/2602	17/18639	0.176470588235294	1.26411809919971	0.430505137166458	0.857011774606913
GO:0060229	lipase activator activity	4/2602	24/18639	0.166666666666667	1.19388931591084	0.436429706304039	0.864665809158731
GO:0070300	phosphatidic acid binding	4/2602	24/18639	0.166666666666667	1.19388931591084	0.436429706304039	0.864665809158731
GO:0140033	acetylation-dependent protein binding	4/2602	24/18639	0.166666666666667	1.19388931591084	0.436429706304039	0.864665809158731
GO:0008327	methyl-CpG binding	5/2602	31/18639	0.161290322580645	1.15537675733307	0.439512853122454	0.864665809158731
GO:0016878	acid-thiol ligase activity	5/2602	31/18639	0.161290322580645	1.15537675733307	0.439512853122454	0.864665809158731
GO:0042887	amide transmembrane transporter activity	6/2602	38/18639	0.157894736842105	1.13105303612606	0.441216779532105	0.864665809158731
GO:0001786	phosphatidylserine binding	9/2602	59/18639	0.152542372881356	1.09271225524043	0.442745893355536	0.864665809158731
GO:0031593	polyubiquitin modification-dependent protein binding	9/2602	59/18639	0.152542372881356	1.09271225524043	0.442745893355536	0.864665809158731
GO:0008276	protein methyltransferase activity	14/2602	95/18639	0.147368421052632	1.05564950038432	0.457808622395791	0.864665809158731
GO:0033192	calmodulin-dependent protein phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:0140791	histone H2AXS140 phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:1990439	MAP kinase serine/threonine phosphatase activity	12/2602	81/18639	0.148148148148148	1.0612349474763	0.460082045790017	0.864665809158731
GO:0016791	phosphatase activity	39/2602	273/18639	0.142857142857143	1.02333369935215	0.464571558792536	0.864665809158731
GO:0000217	DNA secondary structure binding	6/2602	39/18639	0.153846153846154	1.10205167622539	0.467250878562209	0.864665809158731
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0003953	NAD+ nucleosidase activity	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0004016	adenylate cyclase activity	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0004954	prostanoid receptor activity	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0005225	volume-sensitive anion channel activity	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0032050	clathrin heavy chain binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0032794	GTPase activating protein binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0034056	estrogen response element binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0042608	T cell receptor binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0045294	alpha-catenin binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0050786	RAGE receptor binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0050998	nitric-oxide synthase binding	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/2602	11/18639	0.181818181818182	1.30242470826637	0.467331250072324	0.864665809158731
GO:0008378	galactosyltransferase activity	5/2602	32/18639	0.15625	1.11927123366641	0.468323171149519	0.864665809158731
GO:0042910	xenobiotic transmembrane transporter activity	5/2602	32/18639	0.15625	1.11927123366641	0.468323171149519	0.864665809158731
GO:0070717	poly-purine tract binding	5/2602	32/18639	0.15625	1.11927123366641	0.468323171149519	0.864665809158731
GO:0000030	mannosyltransferase activity	4/2602	25/18639	0.16	1.1461337432744	0.46914584601058	0.864665809158731
GO:0015662	P-type ion transporter activity	4/2602	25/18639	0.16	1.1461337432744	0.46914584601058	0.864665809158731
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	4/2602	25/18639	0.16	1.1461337432744	0.46914584601058	0.864665809158731
GO:0047617	fatty acyl-CoA hydrolase activity	4/2602	25/18639	0.16	1.1461337432744	0.46914584601058	0.864665809158731
GO:0140358	P-type transmembrane transporter activity	4/2602	25/18639	0.16	1.1461337432744	0.46914584601058	0.864665809158731
GO:0000400	four-way junction DNA binding	3/2602	18/18639	0.166666666666667	1.19388931591084	0.469313168579156	0.864665809158731
GO:0015172	acidic amino acid transmembrane transporter activity	3/2602	18/18639	0.166666666666667	1.19388931591084	0.469313168579156	0.864665809158731
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2602	18/18639	0.166666666666667	1.19388931591084	0.469313168579156	0.864665809158731
GO:0031690	adrenergic receptor binding	3/2602	18/18639	0.166666666666667	1.19388931591084	0.469313168579156	0.864665809158731
GO:0034185	apolipoprotein binding	3/2602	18/18639	0.166666666666667	1.19388931591084	0.469313168579156	0.864665809158731
GO:0035615	clathrin adaptor activity	3/2602	18/18639	0.166666666666667	1.19388931591084	0.469313168579156	0.864665809158731
GO:1901611	phosphatidylglycerol binding	3/2602	18/18639	0.166666666666667	1.19388931591084	0.469313168579156	0.864665809158731
GO:0016407	acetyltransferase activity	14/2602	96/18639	0.145833333333333	1.04465315142198	0.474318701908356	0.872637840706933
GO:0033549	MAP kinase phosphatase activity	12/2602	82/18639	0.146341463414634	1.04829305787293	0.477958075187064	0.878077263843664
GO:0019003	GDP binding	11/2602	75/18639	0.146666666666667	1.05062259800154	0.479951555837133	0.880481741521473
GO:0140223	general transcription initiation factor activity	10/2602	68/18639	0.147058823529412	1.05343174933309	0.48209037380621	0.883145613553826
GO:0003925	G protein activity	8/2602	54/18639	0.148148148148148	1.0612349474763	0.486940797255672	0.886615950324909
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	8/2602	54/18639	0.148148148148148	1.0612349474763	0.486940797255672	0.886615950324909
GO:0005504	fatty acid binding	7/2602	47/18639	0.148936170212766	1.0668798142182	0.489756758135121	0.886615950324909
GO:0140938	histone H3 methyltransferase activity	7/2602	47/18639	0.148936170212766	1.0668798142182	0.489756758135121	0.886615950324909
GO:0001540	amyloid-beta binding	12/2602	83/18639	0.144578313253012	1.03566302103109	0.495722130688218	0.886615950324909
GO:0030296	protein tyrosine kinase activator activity	5/2602	33/18639	0.151515151515152	1.08535392355531	0.496653719045523	0.886615950324909
GO:0140416	transcription regulator inhibitor activity	5/2602	33/18639	0.151515151515152	1.08535392355531	0.496653719045523	0.886615950324909
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/2602	26/18639	0.153846153846154	1.10205167622539	0.501134335462554	0.886615950324909
GO:0004529	DNA exonuclease activity	4/2602	26/18639	0.153846153846154	1.10205167622539	0.501134335462554	0.886615950324909
GO:0005160	transforming growth factor beta receptor binding	4/2602	26/18639	0.153846153846154	1.10205167622539	0.501134335462554	0.886615950324909
GO:0008157	protein phosphatase 1 binding	4/2602	26/18639	0.153846153846154	1.10205167622539	0.501134335462554	0.886615950324909
GO:0015216	purine nucleotide transmembrane transporter activity	4/2602	26/18639	0.153846153846154	1.10205167622539	0.501134335462554	0.886615950324909
GO:0016289	acyl-CoA hydrolase activity	4/2602	26/18639	0.153846153846154	1.10205167622539	0.501134335462554	0.886615950324909
GO:0042578	phosphoric ester hydrolase activity	51/2602	363/18639	0.140495867768595	1.00641909275128	0.50359586384301	0.886615950324909
GO:0008301	DNA binding, bending	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0008574	plus-end-directed microtubule motor activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0022821	solute:potassium antiporter activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0022840	leak channel activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0022842	narrow pore channel activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0042800	histone H3K4 methyltransferase activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0046624	sphingolipid transporter activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0050145	nucleoside monophosphate kinase activity	3/2602	19/18639	0.157894736842105	1.13105303612606	0.506878555196739	0.886615950324909
GO:0042626	ATPase-coupled transmembrane transporter activity	14/2602	98/18639	0.142857142857143	1.02333369935215	0.507074945245247	0.886615950324909
GO:0042277	peptide binding	35/2602	249/18639	0.140562248995984	1.00689460378022	0.510502090322901	0.886615950324909
GO:0017018	myosin phosphatase activity	12/2602	84/18639	0.142857142857143	1.02333369935215	0.513341869991548	0.886615950324909
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0004300	enoyl-CoA hydratase activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0005025	transforming growth factor beta receptor activity, type I	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0005026	transforming growth factor beta receptor activity, type II	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0008504	monoamine transmembrane transporter activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0015368	calcium:monoatomic cation antiporter activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0016208	AMP binding	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0016361	activin receptor activity, type I	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0016362	activin receptor activity, type II	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0016423	tRNA (guanine) methyltransferase activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0017002	activin receptor activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0035197	siRNA binding	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0035259	nuclear glucocorticoid receptor binding	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0070008	serine-type exopeptidase activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/2602	12/18639	0.166666666666667	1.19388931591084	0.515009420600861	0.886615950324909
GO:0004812	aminoacyl-tRNA ligase activity	6/2602	41/18639	0.146341463414634	1.04829305787293	0.518212241874031	0.889747587516695
GO:0016875	ligase activity, forming carbon-oxygen bonds	6/2602	41/18639	0.146341463414634	1.04829305787293	0.518212241874031	0.889747587516695
GO:0016278	lysine N-methyltransferase activity	10/2602	70/18639	0.142857142857143	1.02333369935215	0.52085244932711	0.893088333112884
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/2602	34/18639	0.147058823529412	1.05343174933309	0.524392163562522	0.897960482478566
GO:0043178	alcohol binding	13/2602	92/18639	0.141304347826087	1.01221050696788	0.526866111706667	0.900997100604752
GO:0019842	vitamin binding	21/2602	150/18639	0.14	1.0028670253651	0.530327170576871	0.905173429445982
GO:0015291	secondary active transmembrane transporter activity	40/2602	287/18639	0.139372822299652	0.998374340831363	0.530715992070195	0.905173429445982
GO:0023026	MHC class II protein complex binding	4/2602	27/18639	0.148148148148148	1.0612349474763	0.532247902938553	0.906583845270171
GO:0008234	cysteine-type peptidase activity	26/2602	187/18639	0.13903743315508	0.995971835733105	0.541221704356872	0.917611034961521
GO:0019894	kinesin binding	6/2602	42/18639	0.142857142857143	1.02333369935215	0.542971462935726	0.917611034961521
GO:0048487	beta-tubulin binding	6/2602	42/18639	0.142857142857143	1.02333369935215	0.542971462935726	0.917611034961521
GO:0015095	magnesium ion transmembrane transporter activity	3/2602	20/18639	0.15	1.07450038431975	0.5430031085581	0.917611034961521
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/2602	20/18639	0.15	1.07450038431975	0.5430031085581	0.917611034961521
GO:0042288	MHC class I protein binding	3/2602	20/18639	0.15	1.07450038431975	0.5430031085581	0.917611034961521
GO:0005496	steroid binding	15/2602	108/18639	0.138888888888889	0.994907763259032	0.550844703808119	0.927646716121978
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2602	57/18639	0.140350877192982	1.0053804765565	0.551429722881884	0.927646716121978
GO:0016798	hydrolase activity, acting on glycosyl bonds	18/2602	130/18639	0.138461538461538	0.99184650860285	0.553617656818158	0.927646716121978
GO:0005126	cytokine receptor binding	38/2602	275/18639	0.138181818181818	0.98984277828244	0.554040588389641	0.927646716121978
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0008417	fucosyltransferase activity	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0019855	calcium channel inhibitor activity	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0045159	myosin II binding	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0051011	microtubule minus-end binding	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0061459	L-arginine transmembrane transporter activity	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0071837	HMG box domain binding	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/2602	13/18639	0.153846153846154	1.10205167622539	0.559761937566606	0.927646716121978
GO:0016866	intramolecular transferase activity	4/2602	28/18639	0.142857142857143	1.02333369935215	0.56236472290716	0.929564310615177
GO:0046625	sphingolipid binding	4/2602	28/18639	0.142857142857143	1.02333369935215	0.56236472290716	0.929564310615177
GO:0160215	deacylase activity	9/2602	65/18639	0.138461538461538	0.99184650860285	0.564952836818144	0.931586391877622
GO:0008081	phosphoric diester hydrolase activity	12/2602	87/18639	0.137931034482759	0.988046330408969	0.565036847328573	0.931586391877622
GO:0008514	organic anion transmembrane transporter activity	37/2602	269/18639	0.137546468401487	0.985291554394818	0.56604735580752	0.932057489844393
GO:0048306	calcium-dependent protein binding	11/2602	80/18639	0.1375	0.984958685626441	0.570731133794211	0.936452429639631
GO:0008238	exopeptidase activity	14/2602	102/18639	0.137254901960784	0.983202966044219	0.570839788375726	0.936452429639631
GO:0004721	phosphoprotein phosphatase activity	24/2602	175/18639	0.137142857142857	0.982400351378061	0.570901014648111	0.936452429639631
GO:0015174	basic amino acid transmembrane transporter activity	3/2602	21/18639	0.142857142857143	1.02333369935215	0.577538639458377	0.942531332923189
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	3/2602	21/18639	0.142857142857143	1.02333369935215	0.577538639458377	0.942531332923189
GO:0051010	microtubule plus-end binding	3/2602	21/18639	0.142857142857143	1.02333369935215	0.577538639458377	0.942531332923189
GO:0140312	cargo adaptor activity	3/2602	21/18639	0.142857142857143	1.02333369935215	0.577538639458377	0.942531332923189
GO:0004197	cysteine-type endopeptidase activity	12/2602	88/18639	0.136363636363636	0.976818531199776	0.581789941490813	0.948265988285406
GO:0008235	metalloexopeptidase activity	9/2602	66/18639	0.136363636363636	0.976818531199776	0.584259569421877	0.95108583072979
GO:0003785	actin monomer binding	4/2602	29/18639	0.137931034482759	0.988046330408969	0.591386909503055	0.955254226711044
GO:0004065	arylsulfatase activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0004705	JUN kinase activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0005313	L-glutamate transmembrane transporter activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0008494	translation activator activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0008559	ABC-type xenobiotic transporter activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0015926	glucosidase activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0019992	diacylglycerol binding	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0031404	chloride ion binding	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0044548	S100 protein binding	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0098599	palmitoyl hydrolase activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0098821	BMP receptor activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:1901474	azole transmembrane transporter activity	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:1901612	cardiolipin binding	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:1990825	sequence-specific mRNA binding	2/2602	14/18639	0.142857142857143	1.02333369935215	0.601476252143046	0.955254226711044
GO:0015078	proton transmembrane transporter activity	25/2602	185/18639	0.135135135135135	0.968018364252031	0.60225497221975	0.955254226711044
GO:0019213	deacetylase activity	5/2602	37/18639	0.135135135135135	0.968018364252031	0.603150479448465	0.955254226711044
GO:0030551	cyclic nucleotide binding	5/2602	37/18639	0.135135135135135	0.968018364252031	0.603150479448465	0.955254226711044
GO:0070001	aspartic-type peptidase activity	5/2602	37/18639	0.135135135135135	0.968018364252031	0.603150479448465	0.955254226711044
GO:0042054	histone methyltransferase activity	9/2602	67/18639	0.134328358208955	0.962239150137093	0.60316207782999	0.955254226711044
GO:0008649	rRNA methyltransferase activity	3/2602	22/18639	0.136363636363636	0.976818531199776	0.610380988004272	0.961948468840067
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2602	22/18639	0.136363636363636	0.976818531199776	0.610380988004272	0.961948468840067
GO:0061133	endopeptidase activator activity	3/2602	22/18639	0.136363636363636	0.976818531199776	0.610380988004272	0.961948468840067
GO:0070034	telomerase RNA binding	3/2602	22/18639	0.136363636363636	0.976818531199776	0.610380988004272	0.961948468840067
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	8/2602	60/18639	0.133333333333333	0.95511145272867	0.612302913730601	0.963796263228339
GO:0022804	active transmembrane transporter activity	62/2602	457/18639	0.135667396061269	0.97183112804996	0.617795747052924	0.971147609550893
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/2602	30/18639	0.133333333333333	0.95511145272867	0.619238755701191	0.971147609550893
GO:0015215	nucleotide transmembrane transporter activity	4/2602	30/18639	0.133333333333333	0.95511145272867	0.619238755701191	0.971147609550893
GO:0030165	PDZ domain binding	11/2602	83/18639	0.132530120481928	0.949357769278498	0.621909657709675	0.973424813665122
GO:0016251	RNA polymerase II general transcription initiation factor activity	7/2602	53/18639	0.132075471698113	0.946100967325569	0.622961603146497	0.973424813665122
GO:1901505	carbohydrate derivative transmembrane transporter activity	7/2602	53/18639	0.132075471698113	0.946100967325569	0.622961603146497	0.973424813665122
GO:0015026	coreceptor activity	8/2602	61/18639	0.131147540983607	0.93945388792984	0.631608139362244	0.97393497469418
GO:0019905	syntaxin binding	8/2602	61/18639	0.131147540983607	0.93945388792984	0.631608139362244	0.97393497469418
GO:0016779	nucleotidyltransferase activity	18/2602	136/18639	0.132352941176471	0.948088574399783	0.634148651444965	0.97393497469418
GO:0004180	carboxypeptidase activity	6/2602	46/18639	0.130434782608696	0.934348160278047	0.635671728831939	0.97393497469418
GO:0004527	exonuclease activity	11/2602	84/18639	0.130952380952381	0.938055891072801	0.638269187365831	0.97393497469418
GO:0016279	protein-lysine N-methyltransferase activity	9/2602	69/18639	0.130434782608696	0.934348160278047	0.639639159506569	0.97393497469418
GO:0004089	carbonate dehydratase activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0004129	cytochrome-c oxidase activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0004953	icosanoid receptor activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0008242	omega peptidase activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0015929	hexosaminidase activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0034483	heparan sulfate sulfotransferase activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0045504	dynein heavy chain binding	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0047372	monoacylglycerol lipase activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0048531	beta-1,3-galactosyltransferase activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0140776	protein-containing complex destabilizing activity	2/2602	15/18639	0.133333333333333	0.95511145272867	0.640128214869837	0.97393497469418
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2602	23/18639	0.130434782608696	0.934348160278047	0.641464170735591	0.97393497469418
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/2602	23/18639	0.130434782608696	0.934348160278047	0.641464170735591	0.97393497469418
GO:0004602	glutathione peroxidase activity	3/2602	23/18639	0.130434782608696	0.934348160278047	0.641464170735591	0.97393497469418
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/2602	23/18639	0.130434782608696	0.934348160278047	0.641464170735591	0.97393497469418
GO:0070577	lysine-acetylated histone binding	3/2602	23/18639	0.130434782608696	0.934348160278047	0.641464170735591	0.97393497469418
GO:0099186	structural constituent of postsynapse	3/2602	23/18639	0.130434782608696	0.934348160278047	0.641464170735591	0.97393497469418
GO:0140102	catalytic activity, acting on a rRNA	3/2602	23/18639	0.130434782608696	0.934348160278047	0.641464170735591	0.97393497469418
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	7/2602	54/18639	0.12962962962963	0.928580579041763	0.64322002104513	0.975449230028346
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2602	31/18639	0.129032258064516	0.924301405866455	0.645864815342486	0.976007229765495
GO:0017147	Wnt-protein binding	4/2602	31/18639	0.129032258064516	0.924301405866455	0.645864815342486	0.976007229765495
GO:0047499	calcium-independent phospholipase A2 activity	4/2602	31/18639	0.129032258064516	0.924301405866455	0.645864815342486	0.976007229765495
GO:0061134	peptidase regulator activity	30/2602	226/18639	0.132743362831858	0.950885295858189	0.646665508334296	0.976070239105522
GO:0098632	cell-cell adhesion mediator activity	7/2602	55/18639	0.127272727272727	0.911697295786458	0.662828501807791	0.996590424513372
GO:0016209	antioxidant activity	11/2602	86/18639	0.127906976744186	0.916240637792038	0.669825122481903	0.996590424513372
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0004806	triacylglycerol lipase activity	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0030215	semaphorin receptor binding	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0030552	cAMP binding	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0070840	dynein complex binding	3/2602	24/18639	0.125	0.895416986933128	0.670754808511527	0.996590424513372
GO:0047498	calcium-dependent phospholipase A2 activity	4/2602	32/18639	0.125	0.895416986933128	0.671227907370052	0.996590424513372
GO:0120015	sterol transfer activity	4/2602	32/18639	0.125	0.895416986933128	0.671227907370052	0.996590424513372
GO:0003779	actin binding	59/2602	443/18639	0.133182844243792	0.954033448831685	0.674065505184366	0.996590424513372
GO:0004708	MAP kinase kinase activity	2/2602	16/18639	0.125	0.895416986933128	0.675759603558057	0.996590424513372
GO:0015923	mannosidase activity	2/2602	16/18639	0.125	0.895416986933128	0.675759603558057	0.996590424513372
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/2602	16/18639	0.125	0.895416986933128	0.675759603558057	0.996590424513372
GO:0030275	LRR domain binding	2/2602	16/18639	0.125	0.895416986933128	0.675759603558057	0.996590424513372
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2602	16/18639	0.125	0.895416986933128	0.675759603558057	0.996590424513372
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/2602	16/18639	0.125	0.895416986933128	0.675759603558057	0.996590424513372
GO:0033293	monocarboxylic acid binding	10/2602	79/18639	0.126582278481013	0.906751379172788	0.679666804448958	0.999999999986392
GO:0015171	amino acid transmembrane transporter activity	13/2602	102/18639	0.127450980392157	0.912974182755347	0.681439382337374	0.999999999986392
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/2602	41/18639	0.121951219512195	0.873577548227442	0.695521442222667	0.999999999986392
GO:0035254	glutamate receptor binding	6/2602	49/18639	0.122448979591837	0.877143170873269	0.697329016903012	0.999999999986392
GO:0120020	cholesterol transfer activity	3/2602	25/18639	0.12	0.859600307455803	0.698246939761656	0.999999999986392
GO:0004601	peroxidase activity	7/2602	57/18639	0.12280701754386	0.879707916986933	0.700011590395926	0.999999999986392
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0004550	nucleoside diphosphate kinase activity	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0008484	sulfuric ester hydrolase activity	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0008569	minus-end-directed microtubule motor activity	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0030169	low-density lipoprotein particle binding	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0031489	myosin V binding	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0036041	long-chain fatty acid binding	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0051787	misfolded protein binding	2/2602	17/18639	0.117647058823529	0.842745399466474	0.708460199076936	0.999999999986392
GO:0015101	organic cation transmembrane transporter activity	10/2602	81/18639	0.123456790123457	0.88436245623025	0.710314986140751	0.999999999986392
GO:0005200	structural constituent of cytoskeleton	14/2602	112/18639	0.125	0.895416986933128	0.712868586977372	0.999999999986392
GO:0042056	chemoattractant activity	5/2602	42/18639	0.119047619047619	0.852778082793455	0.71613630428847	0.999999999986392
GO:0015399	primary active transmembrane transporter activity	21/2602	166/18639	0.126506024096386	0.906205143402202	0.720412683737828	0.999999999986392
GO:0004435	phosphatidylinositol phospholipase C activity	3/2602	26/18639	0.115384615384615	0.826538757169042	0.723957279452844	0.999999999986392
GO:0008143	poly(A) binding	3/2602	26/18639	0.115384615384615	0.826538757169042	0.723957279452844	0.999999999986392
GO:0008198	ferrous iron binding	3/2602	26/18639	0.115384615384615	0.826538757169042	0.723957279452844	0.999999999986392
GO:0030247	polysaccharide binding	3/2602	26/18639	0.115384615384615	0.826538757169042	0.723957279452844	0.999999999986392
GO:0097602	cullin family protein binding	3/2602	26/18639	0.115384615384615	0.826538757169042	0.723957279452844	0.999999999986392
GO:0044325	transmembrane transporter binding	17/2602	136/18639	0.125	0.895416986933128	0.725255962558259	0.999999999986392
GO:0140789	histone phosphatase activity	17/2602	136/18639	0.125	0.895416986933128	0.725255962558259	0.999999999986392
GO:0000149	SNARE binding	13/2602	106/18639	0.122641509433962	0.878522326802315	0.734226554393521	0.999999999986392
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/2602	59/18639	0.11864406779661	0.849887309631444	0.73439414501863	0.999999999986392
GO:0017075	syntaxin-1 binding	2/2602	18/18639	0.111111111111111	0.795926210607225	0.738353577889159	0.999999999986392
GO:0022851	GABA-gated chloride ion channel activity	2/2602	18/18639	0.111111111111111	0.795926210607225	0.738353577889159	0.999999999986392
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2602	18/18639	0.111111111111111	0.795926210607225	0.738353577889159	0.999999999986392
GO:0070064	proline-rich region binding	2/2602	18/18639	0.111111111111111	0.795926210607225	0.738353577889159	0.999999999986392
GO:0070628	proteasome binding	2/2602	18/18639	0.111111111111111	0.795926210607225	0.738353577889159	0.999999999986392
GO:1990381	ubiquitin-specific protease binding	2/2602	18/18639	0.111111111111111	0.795926210607225	0.738353577889159	0.999999999986392
GO:0000175	3'-5'-RNA exonuclease activity	4/2602	35/18639	0.114285714285714	0.818666959481717	0.739599616744579	0.999999999986392
GO:0004623	phospholipase A2 activity	4/2602	35/18639	0.114285714285714	0.818666959481717	0.739599616744579	0.999999999986392
GO:0061631	ubiquitin conjugating enzyme activity	4/2602	35/18639	0.114285714285714	0.818666959481717	0.739599616744579	0.999999999986392
GO:0005104	fibroblast growth factor receptor binding	3/2602	27/18639	0.111111111111111	0.795926210607225	0.74792095151713	0.999999999986392
GO:0016790	thiolester hydrolase activity	5/2602	44/18639	0.113636363636364	0.81401544266648	0.754334514129848	0.999999999986392
GO:0004843	cysteine-type deubiquitinase activity	13/2602	108/18639	0.12037037037037	0.862253394824494	0.758376371309319	0.999999999986392
GO:0004190	aspartic-type endopeptidase activity	4/2602	36/18639	0.111111111111111	0.795926210607225	0.759834970941096	0.999999999986392
GO:0005484	SNAP receptor activity	4/2602	36/18639	0.111111111111111	0.795926210607225	0.759834970941096	0.999999999986392
GO:0016409	palmitoyltransferase activity	4/2602	36/18639	0.111111111111111	0.795926210607225	0.759834970941096	0.999999999986392
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/2602	132/18639	0.121212121212121	0.868283138844246	0.765446084273199	0.999999999986392
GO:0003756	protein disulfide isomerase activity	2/2602	19/18639	0.105263157894737	0.754035357417371	0.765585933500032	0.999999999986392
GO:0004890	GABA-A receptor activity	2/2602	19/18639	0.105263157894737	0.754035357417371	0.765585933500032	0.999999999986392
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/2602	19/18639	0.105263157894737	0.754035357417371	0.765585933500032	0.999999999986392
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/2602	19/18639	0.105263157894737	0.754035357417371	0.765585933500032	0.999999999986392
GO:0034987	immunoglobulin receptor binding	2/2602	19/18639	0.105263157894737	0.754035357417371	0.765585933500032	0.999999999986392
GO:0042834	peptidoglycan binding	2/2602	19/18639	0.105263157894737	0.754035357417371	0.765585933500032	0.999999999986392
GO:0120227	acyl-CoA binding	2/2602	19/18639	0.105263157894737	0.754035357417371	0.765585933500032	0.999999999986392
GO:0008146	sulfotransferase activity	6/2602	53/18639	0.113207547169811	0.81094368627906	0.768001262262059	0.999999999986392
GO:0019789	SUMO transferase activity	3/2602	28/18639	0.107142857142857	0.76750027451411	0.770187698950326	0.999999999986392
GO:0050698	proteoglycan sulfotransferase activity	3/2602	28/18639	0.107142857142857	0.76750027451411	0.770187698950326	0.999999999986392
GO:0051537	2 iron, 2 sulfur cluster binding	3/2602	28/18639	0.107142857142857	0.76750027451411	0.770187698950326	0.999999999986392
GO:0042605	peptide antigen binding	5/2602	45/18639	0.111111111111111	0.795926210607225	0.771932483724671	0.999999999986392
GO:0000182	rDNA binding	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0003796	lysozyme activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0005528	FK506 binding	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0008140	cAMP response element binding protein binding	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0008239	dipeptidyl-peptidase activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0015187	glycine transmembrane transporter activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0015279	store-operated calcium channel activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0016868	intramolecular phosphotransferase activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0019531	oxalate transmembrane transporter activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0032052	bile acid binding	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0051880	G-quadruplex DNA binding	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0071723	lipopeptide binding	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0098505	G-rich strand telomeric DNA binding	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2602	10/18639	0.1	0.716333589546503	0.777753451535249	0.999999999986392
GO:0022829	wide pore channel activity	4/2602	37/18639	0.108108108108108	0.774414691401625	0.778827030515961	0.999999999986392
GO:0023023	MHC protein complex binding	4/2602	37/18639	0.108108108108108	0.774414691401625	0.778827030515961	0.999999999986392
GO:0042805	actinin binding	4/2602	37/18639	0.108108108108108	0.774414691401625	0.778827030515961	0.999999999986392
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/2602	46/18639	0.108695652173913	0.778623466898372	0.788549648955492	0.999999999986392
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/2602	20/18639	0.1	0.716333589546503	0.79031735849358	0.999999999986392
GO:0005326	neurotransmitter transmembrane transporter activity	2/2602	20/18639	0.1	0.716333589546503	0.79031735849358	0.999999999986392
GO:0004867	serine-type endopeptidase inhibitor activity	11/2602	95/18639	0.115789473684211	0.829438893159108	0.790529245104663	0.999999999986392
GO:0004629	phospholipase C activity	3/2602	29/18639	0.103448275862069	0.741034747806727	0.790818559271166	0.999999999986392
GO:0016417	S-acyltransferase activity	3/2602	29/18639	0.103448275862069	0.741034747806727	0.790818559271166	0.999999999986392
GO:0106222	lncRNA binding	3/2602	29/18639	0.103448275862069	0.741034747806727	0.790818559271166	0.999999999986392
GO:0019783	ubiquitin-like protein peptidase activity	15/2602	127/18639	0.118110236220472	0.846063294739964	0.793977412496725	0.999999999986392
GO:0005109	frizzled binding	4/2602	38/18639	0.105263157894737	0.754035357417371	0.796608341338226	0.999999999986392
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	4/2602	38/18639	0.105263157894737	0.754035357417371	0.796608341338226	0.999999999986392
GO:0016651	oxidoreductase activity, acting on NAD(P)H	10/2602	88/18639	0.113636363636364	0.81401544266648	0.802152820776003	0.999999999986392
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0002162	dystroglycan binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0005536	D-glucose binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0008172	S-methyltransferase activity	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0008503	benzodiazepine receptor activity	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0010854	adenylate cyclase regulator activity	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0015217	ADP transmembrane transporter activity	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0019206	nucleoside kinase activity	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0019215	intermediate filament binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0034713	type I transforming growth factor beta receptor binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0043522	leucine zipper domain binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0048185	activin binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0070990	snRNP binding	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/2602	11/18639	0.0909090909090909	0.651212354133184	0.808795671681541	0.999999999986392
GO:0031210	phosphatidylcholine binding	3/2602	30/18639	0.1	0.716333589546503	0.809882981890052	0.999999999986392
GO:0098918	structural constituent of synapse	3/2602	30/18639	0.1	0.716333589546503	0.809882981890052	0.999999999986392
GO:0008373	sialyltransferase activity	2/2602	21/18639	0.0952380952380952	0.682222466234764	0.812715118392022	0.999999999986392
GO:0015125	bile acid transmembrane transporter activity	2/2602	21/18639	0.0952380952380952	0.682222466234764	0.812715118392022	0.999999999986392
GO:0061891	calcium ion sensor activity	2/2602	21/18639	0.0952380952380952	0.682222466234764	0.812715118392022	0.999999999986392
GO:1904047	S-adenosyl-L-methionine binding	2/2602	21/18639	0.0952380952380952	0.682222466234764	0.812715118392022	0.999999999986392
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/2602	39/18639	0.102564102564103	0.734701117483592	0.813217377794594	0.999999999986392
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	14/2602	122/18639	0.114754098360656	0.82202215193861	0.821685481198498	0.999999999986392
GO:0016298	lipase activity	15/2602	130/18639	0.115384615384615	0.826538757169042	0.821968100769537	0.999999999986392
GO:0008170	N-methyltransferase activity	11/2602	98/18639	0.112244897959184	0.80404790663383	0.822725010540039	0.999999999986392
GO:0008083	growth factor activity	19/2602	162/18639	0.117283950617284	0.840144333418738	0.82494235203621	0.999999999986392
GO:0048029	monosaccharide binding	8/2602	74/18639	0.108108108108108	0.774414691401625	0.828680551309288	0.999999999986392
GO:0004532	RNA exonuclease activity	4/2602	40/18639	0.1	0.716333589546503	0.828697267659613	0.999999999986392
GO:0050997	quaternary ammonium group binding	4/2602	40/18639	0.1	0.716333589546503	0.828697267659613	0.999999999986392
GO:0101005	deubiquitinase activity	13/2602	115/18639	0.11304347826087	0.809768405574307	0.830905539041444	0.999999999986392
GO:0008970	phospholipase A1 activity	2/2602	22/18639	0.0909090909090909	0.651212354133184	0.832948531430797	0.999999999986392
GO:0140784	metal ion sensor activity	2/2602	22/18639	0.0909090909090909	0.651212354133184	0.832948531430797	0.999999999986392
GO:0004126	cytidine deaminase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0005049	nuclear export signal receptor activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0005436	sodium:phosphate symporter activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0005527	macrolide binding	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0010853	cyclase activator activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0015166	polyol transmembrane transporter activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0016801	hydrolase activity, acting on ether bonds	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0016803	ether hydrolase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0017166	vinculin binding	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0031543	peptidyl-proline dioxygenase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0035497	cAMP response element binding	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0042301	phosphate ion binding	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0043047	single-stranded telomeric DNA binding	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0070410	co-SMAD binding	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:1990459	transferrin receptor binding	1/2602	12/18639	0.0833333333333333	0.596944657955419	0.835503512688876	0.999999999986392
GO:0008408	3'-5' exonuclease activity	6/2602	58/18639	0.103448275862069	0.741034747806727	0.838068543319282	0.999999999986392
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	6/2602	58/18639	0.103448275862069	0.741034747806727	0.838068543319282	0.999999999986392
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4/2602	41/18639	0.0975609756097561	0.698862038581954	0.843094654193338	0.999999999986392
GO:0015106	bicarbonate transmembrane transporter activity	3/2602	32/18639	0.09375	0.671562740199846	0.843617920619419	0.999999999986392
GO:0071813	lipoprotein particle binding	3/2602	32/18639	0.09375	0.671562740199846	0.843617920619419	0.999999999986392
GO:0071814	protein-lipid complex binding	3/2602	32/18639	0.09375	0.671562740199846	0.843617920619419	0.999999999986392
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	7/2602	67/18639	0.104477611940299	0.748408227884406	0.843943552933644	0.999999999986392
GO:0004620	phospholipase activity	12/2602	109/18639	0.110091743119266	0.788624135280553	0.849430516042837	0.999999999986392
GO:0015459	potassium channel regulator activity	6/2602	59/18639	0.101694915254237	0.728474836826952	0.849805267655205	0.999999999986392
GO:0036002	pre-mRNA binding	6/2602	59/18639	0.101694915254237	0.728474836826952	0.849805267655205	0.999999999986392
GO:0070888	E-box binding	6/2602	59/18639	0.101694915254237	0.728474836826952	0.849805267655205	0.999999999986392
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/2602	23/18639	0.0869565217391304	0.622898773518698	0.851185137211293	0.999999999986392
GO:0005212	structural constituent of eye lens	2/2602	23/18639	0.0869565217391304	0.622898773518698	0.851185137211293	0.999999999986392
GO:0016917	GABA receptor activity	2/2602	23/18639	0.0869565217391304	0.622898773518698	0.851185137211293	0.999999999986392
GO:0031681	G-protein beta-subunit binding	2/2602	23/18639	0.0869565217391304	0.622898773518698	0.851185137211293	0.999999999986392
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/2602	23/18639	0.0869565217391304	0.622898773518698	0.851185137211293	0.999999999986392
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	7/2602	68/18639	0.102941176470588	0.737402224533165	0.854659989866024	0.999999999986392
GO:0022853	active monoatomic ion transmembrane transporter activity	13/2602	118/18639	0.110169491525424	0.789181073229198	0.856438423790933	0.999999999986392
GO:0008307	structural constituent of muscle	4/2602	42/18639	0.0952380952380952	0.682222466234764	0.856458691025429	0.999999999986392
GO:0031492	nucleosomal DNA binding	4/2602	42/18639	0.0952380952380952	0.682222466234764	0.856458691025429	0.999999999986392
GO:0019956	chemokine binding	3/2602	33/18639	0.0909090909090909	0.651212354133184	0.858449002105397	0.999999999986392
GO:0002161	aminoacyl-tRNA editing activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0004465	lipoprotein lipase activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0005035	death receptor activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0008253	5'-nucleotidase activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0019104	DNA N-glycosylase activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0032396	inhibitory MHC class I receptor activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0070700	BMP receptor binding	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0089720	caspase binding	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2602	13/18639	0.0769230769230769	0.551025838112694	0.858481977282399	0.999999999986392
GO:0050699	WW domain binding	2/2602	24/18639	0.0833333333333333	0.596944657955419	0.867587894365818	0.999999999986392
GO:0005245	voltage-gated calcium channel activity	4/2602	43/18639	0.0930232558139535	0.666356827485119	0.868840163446013	0.999999999986392
GO:0015020	glucuronosyltransferase activity	3/2602	34/18639	0.0882352941176471	0.632059049599855	0.872031573465345	0.999999999986392
GO:0051427	hormone receptor binding	3/2602	34/18639	0.0882352941176471	0.632059049599855	0.872031573465345	0.999999999986392
GO:0051015	actin filament binding	24/2602	209/18639	0.114832535885167	0.822584026273496	0.874517208122417	0.999999999986392
GO:0005347	ATP transmembrane transporter activity	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0008191	metalloendopeptidase inhibitor activity	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0008331	high voltage-gated calcium channel activity	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0042813	Wnt receptor activity	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0043176	amine binding	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0061665	SUMO ligase activity	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0061783	peptidoglycan muralytic activity	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0071933	Arp2/3 complex binding	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0098847	sequence-specific single stranded DNA binding	1/2602	14/18639	0.0714285714285714	0.511666849676073	0.878251648446964	0.999999999986392
GO:0051082	unfolded protein binding	13/2602	121/18639	0.107438016528926	0.769614600339218	0.878861606067468	0.999999999986392
GO:0004175	endopeptidase activity	49/2602	405/18639	0.120987654320988	0.866675207105645	0.879409647048538	0.999999999986392
GO:0005246	calcium channel regulator activity	5/2602	53/18639	0.0943396226415094	0.67578640523255	0.87962930179122	0.999999999986392
GO:0005506	iron ion binding	17/2602	154/18639	0.11038961038961	0.790757858590295	0.880909371118004	0.999999999986392
GO:0005251	delayed rectifier potassium channel activity	2/2602	25/18639	0.08	0.573066871637202	0.882313194766179	0.999999999986392
GO:0005537	D-mannose binding	2/2602	25/18639	0.08	0.573066871637202	0.882313194766179	0.999999999986392
GO:0015271	outward rectifier potassium channel activity	2/2602	25/18639	0.08	0.573066871637202	0.882313194766179	0.999999999986392
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2602	25/18639	0.08	0.573066871637202	0.882313194766179	0.999999999986392
GO:0019707	protein-cysteine S-acyltransferase activity	2/2602	25/18639	0.08	0.573066871637202	0.882313194766179	0.999999999986392
GO:0016229	steroid dehydrogenase activity	3/2602	35/18639	0.0857142857142857	0.614000219611288	0.884447069407918	0.999999999986392
GO:0070851	growth factor receptor binding	15/2602	139/18639	0.107913669064748	0.773021859222845	0.888995675038916	0.999999999986392
GO:0017069	snRNA binding	5/2602	54/18639	0.0925925925925926	0.663271842172688	0.889428320605204	0.999999999986392
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	9/2602	89/18639	0.101123595505618	0.724382281563879	0.889665158377371	0.999999999986392
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	9/2602	89/18639	0.101123595505618	0.724382281563879	0.889665158377371	0.999999999986392
GO:0008009	chemokine activity	4/2602	45/18639	0.0888888888888889	0.63674096848578	0.890862264441332	0.999999999986392
GO:0004725	protein tyrosine phosphatase activity	10/2602	98/18639	0.102040816326531	0.730952642394391	0.893252839659757	0.999999999986392
GO:0004559	alpha-mannosidase activity	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0008252	nucleotidase activity	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0015116	sulfate transmembrane transporter activity	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0030553	cGMP binding	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0031386	protein tag activity	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0050780	dopamine receptor binding	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0141047	molecular tag activity	1/2602	15/18639	0.0666666666666667	0.477555726364335	0.895260465131045	0.999999999986392
GO:0005227	calcium-activated cation channel activity	2/2602	26/18639	0.0769230769230769	0.551025838112694	0.895509521042291	0.999999999986392
GO:0043548	phosphatidylinositol 3-kinase binding	2/2602	26/18639	0.0769230769230769	0.551025838112694	0.895509521042291	0.999999999986392
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/2602	36/18639	0.0833333333333333	0.596944657955419	0.89577544199581	0.999999999986392
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/2602	36/18639	0.0833333333333333	0.596944657955419	0.89577544199581	0.999999999986392
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/2602	36/18639	0.0833333333333333	0.596944657955419	0.89577544199581	0.999999999986392
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/2602	36/18639	0.0833333333333333	0.596944657955419	0.89577544199581	0.999999999986392
GO:0140793	histone H2AXY142 phosphatase activity	9/2602	90/18639	0.1	0.716333589546503	0.896963558625996	0.999999999986392
GO:0015252	proton channel activity	2/2602	27/18639	0.0740740740740741	0.53061747373815	0.907316606604304	0.999999999986392
GO:0035255	ionotropic glutamate receptor binding	2/2602	27/18639	0.0740740740740741	0.53061747373815	0.907316606604304	0.999999999986392
GO:0030246	carbohydrate binding	32/2602	280/18639	0.114285714285714	0.818666959481717	0.909163565189372	0.999999999986392
GO:0099095	ligand-gated monoatomic anion channel activity	4/2602	47/18639	0.0851063829787234	0.609645608124683	0.909573671372343	0.999999999986392
GO:0000062	fatty-acyl-CoA binding	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0003688	DNA replication origin binding	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0005159	insulin-like growth factor receptor binding	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0008296	3'-5'-DNA exonuclease activity	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0017070	U6 snRNA binding	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0019841	retinol binding	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0022858	alanine transmembrane transporter activity	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0043023	ribosomal large subunit binding	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0097027	ubiquitin-protein transferase activator activity	1/2602	16/18639	0.0625	0.447708493466564	0.909893855902577	0.999999999986392
GO:0052689	carboxylic ester hydrolase activity	9/2602	92/18639	0.0978260869565217	0.700761120208535	0.910352849389348	0.999999999986392
GO:0000146	microfilament motor activity	3/2602	38/18639	0.0789473684210526	0.565526518063028	0.915478940462849	0.999999999986392
GO:0005501	retinoid binding	3/2602	38/18639	0.0789473684210526	0.565526518063028	0.915478940462849	0.999999999986392
GO:0019840	isoprenoid binding	3/2602	38/18639	0.0789473684210526	0.565526518063028	0.915478940462849	0.999999999986392
GO:0046982	protein heterodimerization activity	43/2602	369/18639	0.116531165311653	0.834751879417334	0.916901887631658	0.999999999986392
GO:0038187	pattern recognition receptor activity	4/2602	48/18639	0.0833333333333333	0.596944657955419	0.917813917836348	0.999999999986392
GO:0005242	inward rectifier potassium channel activity	2/2602	28/18639	0.0714285714285714	0.511666849676073	0.917864984116148	0.999999999986392
GO:0045499	chemorepellent activity	2/2602	28/18639	0.0714285714285714	0.511666849676073	0.917864984116148	0.999999999986392
GO:0051119	sugar transmembrane transporter activity	2/2602	28/18639	0.0714285714285714	0.511666849676073	0.917864984116148	0.999999999986392
GO:0051393	alpha-actinin binding	2/2602	28/18639	0.0714285714285714	0.511666849676073	0.917864984116148	0.999999999986392
GO:0141108	transporter regulator activity	18/2602	170/18639	0.105882352941176	0.758470859519826	0.921383482964	0.999999999986392
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/2602	17/18639	0.0588235294117647	0.421372699733237	0.92248345945418	0.999999999986392
GO:0009881	photoreceptor activity	1/2602	17/18639	0.0588235294117647	0.421372699733237	0.92248345945418	0.999999999986392
GO:0016805	dipeptidase activity	1/2602	17/18639	0.0588235294117647	0.421372699733237	0.92248345945418	0.999999999986392
GO:0019198	transmembrane receptor protein phosphatase activity	1/2602	17/18639	0.0588235294117647	0.421372699733237	0.92248345945418	0.999999999986392
GO:0038191	neuropilin binding	1/2602	17/18639	0.0588235294117647	0.421372699733237	0.92248345945418	0.999999999986392
GO:0070492	oligosaccharide binding	1/2602	17/18639	0.0588235294117647	0.421372699733237	0.92248345945418	0.999999999986392
GO:1901567	fatty acid derivative binding	1/2602	17/18639	0.0588235294117647	0.421372699733237	0.92248345945418	0.999999999986392
GO:0031406	carboxylic acid binding	20/2602	187/18639	0.106951871657754	0.766132181333158	0.923547003646378	0.999999999986392
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/2602	39/18639	0.0769230769230769	0.551025838112694	0.92400073735187	0.999999999986392
GO:0004181	metallocarboxypeptidase activity	2/2602	29/18639	0.0689655172413793	0.494023165204485	0.927275830400961	0.999999999986392
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	13/2602	130/18639	0.1	0.716333589546503	0.92971124856307	0.999999999986392
GO:0015085	calcium ion transmembrane transporter activity	15/2602	147/18639	0.102040816326531	0.730952642394391	0.929958855853609	0.999999999986392
GO:0043177	organic acid binding	20/2602	189/18639	0.105820105820106	0.758024962483072	0.931235398155069	0.999999999986392
GO:0015144	carbohydrate transmembrane transporter activity	3/2602	40/18639	0.075	0.537250192159877	0.931728045705297	0.999999999986392
GO:0140662	ATP-dependent protein folding chaperone	3/2602	40/18639	0.075	0.537250192159877	0.931728045705297	0.999999999986392
GO:0019199	transmembrane receptor protein kinase activity	7/2602	78/18639	0.0897435897435897	0.642863477798143	0.932121230912895	0.999999999986392
GO:0004970	glutamate-gated receptor activity	1/2602	18/18639	0.0555555555555556	0.397963105303613	0.933314628958004	0.999999999986392
GO:0015280	ligand-gated sodium channel activity	1/2602	18/18639	0.0555555555555556	0.397963105303613	0.933314628958004	0.999999999986392
GO:0032393	MHC class I receptor activity	1/2602	18/18639	0.0555555555555556	0.397963105303613	0.933314628958004	0.999999999986392
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2602	18/18639	0.0555555555555556	0.397963105303613	0.933314628958004	0.999999999986392
GO:0099602	neurotransmitter receptor regulator activity	1/2602	18/18639	0.0555555555555556	0.397963105303613	0.933314628958004	0.999999999986392
GO:0005262	calcium channel activity	13/2602	131/18639	0.099236641221374	0.710865394206453	0.934039207455344	0.999999999986392
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/2602	30/18639	0.0666666666666667	0.477555726364335	0.935661033866027	0.999999999986392
GO:0022839	monoatomic ion-gated channel activity	2/2602	30/18639	0.0666666666666667	0.477555726364335	0.935661033866027	0.999999999986392
GO:0033612	receptor serine/threonine kinase binding	2/2602	30/18639	0.0666666666666667	0.477555726364335	0.935661033866027	0.999999999986392
GO:0016782	transferase activity, transferring sulphur-containing groups	6/2602	70/18639	0.0857142857142857	0.614000219611288	0.938413520014405	0.999999999986392
GO:0001530	lipopolysaccharide binding	3/2602	41/18639	0.0731707317073171	0.524146528936465	0.938725418719399	0.999999999986392
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/2602	41/18639	0.0731707317073171	0.524146528936465	0.938725418719399	0.999999999986392
GO:0017080	sodium channel regulator activity	3/2602	41/18639	0.0731707317073171	0.524146528936465	0.938725418719399	0.999999999986392
GO:0042287	MHC protein binding	3/2602	41/18639	0.0731707317073171	0.524146528936465	0.938725418719399	0.999999999986392
GO:0061135	endopeptidase regulator activity	19/2602	184/18639	0.103260869565217	0.739692293553454	0.942624683517855	0.999999999986392
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/2602	19/18639	0.0526315789473684	0.377017678708686	0.942632889816781	0.999999999986392
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2602	19/18639	0.0526315789473684	0.377017678708686	0.942632889816781	0.999999999986392
GO:0016918	retinal binding	1/2602	19/18639	0.0526315789473684	0.377017678708686	0.942632889816781	0.999999999986392
GO:0030506	ankyrin binding	1/2602	19/18639	0.0526315789473684	0.377017678708686	0.942632889816781	0.999999999986392
GO:0031420	alkali metal ion binding	1/2602	19/18639	0.0526315789473684	0.377017678708686	0.942632889816781	0.999999999986392
GO:0141147	intracellularly calcium-gated channel activity	1/2602	19/18639	0.0526315789473684	0.377017678708686	0.942632889816781	0.999999999986392
GO:0005452	solute:inorganic anion antiporter activity	2/2602	31/18639	0.0645161290322581	0.462150702933228	0.943123425382491	0.999999999986392
GO:0009055	electron transfer activity	11/2602	116/18639	0.0948275862068965	0.679281852156166	0.943392852316832	0.999999999986392
GO:0016859	cis-trans isomerase activity	3/2602	42/18639	0.0714285714285714	0.511666849676073	0.945053628542012	0.999999999986392
GO:0016247	channel regulator activity	17/2602	168/18639	0.101190476190476	0.724861370374437	0.94519746660691	0.999999999986392
GO:0099106	ion channel regulator activity	16/2602	160/18639	0.1	0.716333589546503	0.946718111735354	0.999999999986392
GO:0046906	tetrapyrrole binding	15/2602	152/18639	0.0986842105263158	0.706908147578786	0.948415448735367	0.999999999986392
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/2602	32/18639	0.0625	0.447708493466564	0.949757125700029	0.999999999986392
GO:0004866	endopeptidase inhibitor activity	16/2602	161/18639	0.0993788819875776	0.711884312592798	0.949868260467073	0.999999999986392
GO:0001972	retinoic acid binding	1/2602	20/18639	0.05	0.358166794773251	0.950649496728528	0.999999999986392
GO:0010851	cyclase regulator activity	1/2602	20/18639	0.05	0.358166794773251	0.950649496728528	0.999999999986392
GO:0016408	C-acyltransferase activity	1/2602	20/18639	0.05	0.358166794773251	0.950649496728528	0.999999999986392
GO:0031418	L-ascorbic acid binding	1/2602	20/18639	0.05	0.358166794773251	0.950649496728528	0.999999999986392
GO:0140939	histone H4 methyltransferase activity	1/2602	20/18639	0.05	0.358166794773251	0.950649496728528	0.999999999986392
GO:0003730	mRNA 3'-UTR binding	28/2602	262/18639	0.106870229007634	0.765547347606949	0.952498821989271	0.999999999986392
GO:0005254	chloride channel activity	7/2602	83/18639	0.0843373493975904	0.604136762268135	0.95500693275127	0.999999999986392
GO:0019239	deaminase activity	2/2602	33/18639	0.0606060606060606	0.434141569422123	0.955647972383554	0.999999999986392
GO:0003954	NADH dehydrogenase activity	3/2602	44/18639	0.0681818181818182	0.488409265599888	0.955926631842254	0.999999999986392
GO:0030547	signaling receptor inhibitor activity	3/2602	44/18639	0.0681818181818182	0.488409265599888	0.955926631842254	0.999999999986392
GO:0015293	symporter activity	14/2602	146/18639	0.0958904109589041	0.686895222852811	0.956367785273176	0.999999999986392
GO:0070182	DNA polymerase binding	1/2602	21/18639	0.0476190476190476	0.341111233117382	0.957546215645353	0.999999999986392
GO:0017171	serine hydrolase activity	20/2602	198/18639	0.101010101010101	0.723569282370205	0.958268285767333	0.999999999986392
GO:0044183	protein folding chaperone	6/2602	75/18639	0.08	0.573066871637202	0.960300935856309	0.999999999986392
GO:0005253	monoatomic anion channel activity	9/2602	103/18639	0.087378640776699	0.625922553972672	0.960402173328621	0.999999999986392
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/2602	34/18639	0.0588235294117647	0.421372699733237	0.960873997315942	0.999999999986392
GO:0019825	oxygen binding	2/2602	34/18639	0.0588235294117647	0.421372699733237	0.960873997315942	0.999999999986392
GO:0005243	gap junction channel activity	1/2602	22/18639	0.0454545454545455	0.325606177066592	0.963479438703189	0.999999999986392
GO:0015377	chloride:monoatomic cation symporter activity	1/2602	22/18639	0.0454545454545455	0.325606177066592	0.963479438703189	0.999999999986392
GO:0033691	sialic acid binding	1/2602	22/18639	0.0454545454545455	0.325606177066592	0.963479438703189	0.999999999986392
GO:0017022	myosin binding	6/2602	76/18639	0.0789473684210526	0.565526518063028	0.963719672001342	0.999999999986392
GO:0005154	epidermal growth factor receptor binding	2/2602	35/18639	0.0571428571428571	0.409333479740859	0.965505932340671	0.999999999986392
GO:0004252	serine-type endopeptidase activity	17/2602	176/18639	0.0965909090909091	0.691913126266508	0.966348559670103	0.999999999986392
GO:0008236	serine-type peptidase activity	19/2602	194/18639	0.0979381443298969	0.701563824813585	0.967998952205666	0.999999999986392
GO:0020037	heme binding	13/2602	142/18639	0.0915492957746479	0.65579835662708	0.96841967353622	0.999999999986392
GO:0003887	DNA-directed DNA polymerase activity	1/2602	23/18639	0.0434782608695652	0.311449386759349	0.968583725134639	0.999999999986392
GO:0005158	insulin receptor binding	1/2602	23/18639	0.0434782608695652	0.311449386759349	0.968583725134639	0.999999999986392
GO:0016493	C-C chemokine receptor activity	1/2602	23/18639	0.0434782608695652	0.311449386759349	0.968583725134639	0.999999999986392
GO:0004497	monooxygenase activity	9/2602	106/18639	0.0849056603773585	0.608207764709295	0.968749764756149	0.999999999986392
GO:0004033	aldo-keto reductase (NADPH) activity	2/2602	36/18639	0.0555555555555556	0.397963105303613	0.969607725890368	0.999999999986392
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/2602	36/18639	0.0555555555555556	0.397963105303613	0.969607725890368	0.999999999986392
GO:0045505	dynein intermediate chain binding	2/2602	36/18639	0.0555555555555556	0.397963105303613	0.969607725890368	0.999999999986392
GO:0030414	peptidase inhibitor activity	16/2602	169/18639	0.0946745562130177	0.678185646907931	0.969753395992005	0.999999999986392
GO:0015294	solute:monoatomic cation symporter activity	10/2602	116/18639	0.0862068965517241	0.617528956505606	0.970671624548238	0.999999999986392
GO:0005315	phosphate transmembrane transporter activity	1/2602	24/18639	0.0416666666666667	0.298472328977709	0.972974848211544	0.999999999986392
GO:0015149	hexose transmembrane transporter activity	1/2602	24/18639	0.0416666666666667	0.298472328977709	0.972974848211544	0.999999999986392
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2602	24/18639	0.0416666666666667	0.298472328977709	0.972974848211544	0.999999999986392
GO:0019957	C-C chemokine binding	1/2602	24/18639	0.0416666666666667	0.298472328977709	0.972974848211544	0.999999999986392
GO:0055056	D-glucose transmembrane transporter activity	1/2602	24/18639	0.0416666666666667	0.298472328977709	0.972974848211544	0.999999999986392
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/2602	24/18639	0.0416666666666667	0.298472328977709	0.972974848211544	0.999999999986392
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/2602	25/18639	0.04	0.286533435818601	0.976752417105101	0.999999999986392
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2602	25/18639	0.04	0.286533435818601	0.976752417105101	0.999999999986392
GO:0042379	chemokine receptor binding	5/2602	72/18639	0.0694444444444444	0.497453881629516	0.979348904938554	0.999999999986392
GO:0001637	G protein-coupled chemoattractant receptor activity	1/2602	26/18639	0.0384615384615385	0.275512919056347	0.980002132947614	0.999999999986392
GO:0004950	chemokine receptor activity	1/2602	26/18639	0.0384615384615385	0.275512919056347	0.980002132947614	0.999999999986392
GO:0008066	glutamate receptor activity	1/2602	26/18639	0.0384615384615385	0.275512919056347	0.980002132947614	0.999999999986392
GO:0015145	monosaccharide transmembrane transporter activity	1/2602	26/18639	0.0384615384615385	0.275512919056347	0.980002132947614	0.999999999986392
GO:0019865	immunoglobulin binding	1/2602	26/18639	0.0384615384615385	0.275512919056347	0.980002132947614	0.999999999986392
GO:0030507	spectrin binding	1/2602	26/18639	0.0384615384615385	0.275512919056347	0.980002132947614	0.999999999986392
GO:0005021	vascular endothelial growth factor receptor activity	3/2602	51/18639	0.0588235294117647	0.421372699733237	0.980094512648505	0.999999999986392
GO:0016597	amino acid binding	3/2602	51/18639	0.0588235294117647	0.421372699733237	0.980094512648505	0.999999999986392
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	5/2602	73/18639	0.0684931506849315	0.490639444894865	0.981317931344894	0.999999999986392
GO:0001664	G protein-coupled receptor binding	30/2602	297/18639	0.101010101010101	0.723569282370205	0.981683808419971	0.999999999986392
GO:0071855	neuropeptide receptor binding	2/2602	40/18639	0.05	0.358166794773251	0.981783484431945	0.999999999986392
GO:0008395	steroid hydroxylase activity	1/2602	27/18639	0.037037037037037	0.265308736869075	0.982797730114664	0.999999999986392
GO:0042562	hormone binding	7/2602	94/18639	0.074468085106383	0.533439907109098	0.982860096910037	0.999999999986392
GO:0022834	ligand-gated channel activity	17/2602	188/18639	0.0904255319148936	0.647748458632476	0.984667561142672	0.999999999986392
GO:0051861	glycolipid binding	1/2602	29/18639	0.0344827586206897	0.247011582602242	0.987271461498562	0.999999999986392
GO:0099094	ligand-gated monoatomic cation channel activity	11/2602	136/18639	0.0808823529411765	0.579387462133201	0.987427191037992	0.999999999986392
GO:0016500	protein-hormone receptor activity	4/2602	67/18639	0.0597014925373134	0.427661844505375	0.988524992651174	0.999999999986392
GO:0048019	receptor antagonist activity	1/2602	30/18639	0.0333333333333333	0.238777863182168	0.989051131416926	0.999999999986392
GO:0008509	monoatomic anion transmembrane transporter activity	12/2602	149/18639	0.0805369127516778	0.576912958024029	0.990578685246822	0.999999999986392
GO:0015276	ligand-gated monoatomic ion channel activity	16/2602	186/18639	0.0860215053763441	0.616200937244303	0.990616654322171	0.999999999986392
GO:0015108	chloride transmembrane transporter activity	9/2602	121/18639	0.0743801652892562	0.532810107927151	0.991143155504309	0.999999999986392
GO:0022843	voltage-gated monoatomic cation channel activity	11/2602	143/18639	0.0769230769230769	0.551025838112694	0.992924532359302	0.999999999986392
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/2602	60/18639	0.05	0.358166794773251	0.993138413297445	0.999999999986392
GO:0005004	GPI-linked ephrin receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0005008	hepatocyte growth factor receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0005009	insulin receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0005011	macrophage colony-stimulating factor receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0005020	stem cell factor receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0008288	boss receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0036332	placental growth factor receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0038062	protein tyrosine kinase collagen receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0060175	brain-derived neurotrophic factor receptor activity	2/2602	49/18639	0.0408163265306122	0.292381056957756	0.994391295147426	0.999999999986392
GO:0015103	inorganic anion transmembrane transporter activity	13/2602	165/18639	0.0787878787878788	0.56438404024876	0.994431861438954	0.999999999986392
GO:0034061	DNA polymerase activity	1/2602	35/18639	0.0285714285714286	0.204666739870429	0.994844558714594	0.999999999986392
GO:0005006	epidermal growth factor receptor activity	2/2602	50/18639	0.04	0.286533435818601	0.995088586638842	0.999999999986392
GO:0005007	fibroblast growth factor receptor activity	2/2602	50/18639	0.04	0.286533435818601	0.995088586638842	0.999999999986392
GO:0005017	platelet-derived growth factor receptor activity	2/2602	50/18639	0.04	0.286533435818601	0.995088586638842	0.999999999986392
GO:0005019	platelet-derived growth factor beta-receptor activity	2/2602	50/18639	0.04	0.286533435818601	0.995088586638842	0.999999999986392
GO:0022824	transmitter-gated monoatomic ion channel activity	3/2602	63/18639	0.0476190476190476	0.341111233117382	0.995231054095589	0.999999999986392
GO:0022835	transmitter-gated channel activity	3/2602	63/18639	0.0476190476190476	0.341111233117382	0.995231054095589	0.999999999986392
GO:0005010	insulin-like growth factor receptor activity	2/2602	51/18639	0.0392156862745098	0.280915133155491	0.995700589658856	0.999999999986392
GO:0005030	neurotrophin receptor activity	2/2602	51/18639	0.0392156862745098	0.280915133155491	0.995700589658856	0.999999999986392
GO:0005272	sodium channel activity	2/2602	51/18639	0.0392156862745098	0.280915133155491	0.995700589658856	0.999999999986392
GO:0005249	voltage-gated potassium channel activity	6/2602	98/18639	0.0612244897959184	0.438571585436634	0.995716867053243	0.999999999986392
GO:0030280	structural constituent of skin epidermis	1/2602	37/18639	0.027027027027027	0.193603672850406	0.996185848675326	0.999999999986392
GO:0015079	potassium ion transmembrane transporter activity	12/2602	160/18639	0.075	0.537250192159877	0.996186110238373	0.999999999986392
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/2602	52/18639	0.0384615384615385	0.275512919056347	0.996237516620856	0.999999999986392
GO:0005003	ephrin receptor activity	2/2602	53/18639	0.0377358490566038	0.27031456209302	0.996708392079624	0.999999999986392
GO:0005005	transmembrane-ephrin receptor activity	2/2602	53/18639	0.0377358490566038	0.27031456209302	0.996708392079624	0.999999999986392
GO:0017046	peptide hormone binding	2/2602	53/18639	0.0377358490566038	0.27031456209302	0.996708392079624	0.999999999986392
GO:0038064	collagen receptor activity	2/2602	53/18639	0.0377358490566038	0.27031456209302	0.996708392079624	0.999999999986392
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/2602	53/18639	0.0377358490566038	0.27031456209302	0.996708392079624	0.999999999986392
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/2602	56/18639	0.0357142857142857	0.255833424838037	0.99779982362198	0.999999999986392
GO:0001653	peptide receptor activity	8/2602	128/18639	0.0625	0.447708493466564	0.998219440092328	0.999999999986392
GO:0046873	metal ion transmembrane transporter activity	43/2602	450/18639	0.0955555555555556	0.684496541122214	0.998282003792156	0.999999999986392
GO:0005179	hormone activity	8/2602	132/18639	0.0606060606060606	0.434141569422123	0.99880389876844	0.999999999986392
GO:0015081	sodium ion transmembrane transporter activity	11/2602	164/18639	0.0670731707317073	0.480467651525093	0.998885797245919	0.999999999986392
GO:0008528	G protein-coupled peptide receptor activity	7/2602	122/18639	0.0573770491803279	0.411011075969305	0.998901185607457	0.999999999986392
GO:0005125	cytokine activity	18/2602	234/18639	0.0769230769230769	0.551025838112694	0.998999008625962	0.999999999986392
GO:0022836	gated channel activity	27/2602	318/18639	0.0849056603773585	0.608207764709295	0.999026766687804	0.999999999986392
GO:0005267	potassium channel activity	7/2602	124/18639	0.0564516129032258	0.404381865066574	0.999108367151552	0.999999999986392
GO:0008188	neuropeptide receptor activity	1/2602	48/18639	0.0208333333333333	0.149236164488855	0.999273303979356	0.999999999986392
GO:0005244	voltage-gated monoatomic ion channel activity	11/2602	173/18639	0.0635838150289017	0.45547222456714	0.999519779503767	0.999999999986392
GO:0022832	voltage-gated channel activity	11/2602	175/18639	0.0628571428571429	0.450266827714945	0.999603121604593	0.999999999986392
GO:0098960	postsynaptic neurotransmitter receptor activity	2/2602	69/18639	0.0289855072463768	0.207632924506233	0.999625606772486	0.999999999986392
GO:0015370	solute:sodium symporter activity	2/2602	79/18639	0.0253164556962025	0.181350275834558	0.999906230969154	0.999999999986392
GO:0005216	monoatomic ion channel activity	37/2602	448/18639	0.0825892857142857	0.59161479493796	0.999935767686656	0.999999999986392
GO:0030594	neurotransmitter receptor activity	3/2602	97/18639	0.0309278350515464	0.221546470993764	0.999937342936099	0.999999999986392
GO:0003823	antigen binding	9/2602	174/18639	0.0517241379310345	0.370517373903363	0.999951648588614	0.999999999986392
GO:0005261	monoatomic cation channel activity	25/2602	341/18639	0.0733137829912024	0.525171253333213	0.999958931399381	0.999999999986392
GO:0030527	structural constituent of chromatin	1/2602	98/18639	0.0102040816326531	0.073095264239439	0.999999617514977	0.999999999986392
GO:0045182	translation regulator activity	17/2602	356/18639	0.047752808988764	0.342069410738498	0.99999999682607	0.999999999986392
GO:0030371	translation repressor activity	11/2602	329/18639	0.033434650455927	0.239503631763268	0.999999999986392	0.999999999986392