ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0043021 ribonucleoprotein complex binding 44/1802 177/18639 0.248587570621469 2.57126733008522 3.13026828910574e-09 3.64050202022998e-06 GO:0043022 ribosome binding 29/1802 112/18639 0.258928571428571 2.6782295465356 5.86863031259632e-07 0.000341260852677476 GO:0000287 magnesium ion binding 46/1802 230/18639 0.2 2.06870144284129 1.4325797875516e-06 0.00055536343097417 GO:0032182 ubiquitin-like protein binding 27/1802 120/18639 0.225 2.32728912319645 2.38136946577235e-05 0.00578474832525919 GO:0003735 structural constituent of ribosome 35/1802 175/18639 0.2 2.06870144284129 2.48699412091968e-05 0.00578474832525919 GO:0035091 phosphatidylinositol binding 49/1802 284/18639 0.172535211267606 1.78461920245111 4.50288962749741e-05 0.00813455401213322 GO:0140098 catalytic activity, acting on RNA 62/1802 387/18639 0.160206718346253 1.65709934697881 4.89612021366574e-05 0.00813455401213322 GO:0042393 histone binding 42/1802 247/18639 0.17004048582996 1.75881499188935 0.000211311051104886 0.0307193440543728 GO:0106310 protein serine kinase activity 56/1802 361/18639 0.155124653739612 1.60453297505695 0.00026149739465521 0.0331198877894228 GO:0008135 translation factor activity, RNA binding 19/1802 83/18639 0.228915662650602 2.36779080807135 0.000290360502075516 0.0331198877894228 GO:0043024 ribosomal small subunit binding 8/1802 20/18639 0.4 4.13740288568258 0.000326340540531209 0.0331198877894228 GO:0180051 translation factor activity 19/1802 84/18639 0.226190476190476 2.33960282226098 0.000341735729555523 0.0331198877894228 GO:0001098 basal transcription machinery binding 15/1802 60/18639 0.25 2.58587680355161 0.000454937292690796 0.0340725100405054 GO:0001099 basal RNA polymerase II transcription machinery binding 15/1802 60/18639 0.25 2.58587680355161 0.000454937292690796 0.0340725100405054 GO:0070273 phosphatidylinositol-4-phosphate binding 10/1802 31/18639 0.32258064516129 3.33661523038917 0.00046026148500533 0.0340725100405054 GO:0032266 phosphatidylinositol-3-phosphate binding 13/1802 48/18639 0.270833333333333 2.80136653718091 0.000468753362552095 0.0340725100405054 GO:0031491 nucleosome binding 17/1802 74/18639 0.22972972972973 2.37621111677715 0.000568689233646444 0.0387838355542968 GO:0140142 nucleocytoplasmic carrier activity 10/1802 32/18639 0.3125 3.23234600443951 0.000611993871996585 0.0387838355542968 GO:0032183 SUMO binding 7/1802 17/18639 0.411764705882353 4.25909120584971 0.000633613822469164 0.0387838355542968 GO:0003712 transcription coregulator activity 70/1802 495/18639 0.141414141414141 1.46271819190798 0.000760640555156887 0.044231248282373 GO:1901981 phosphatidylinositol phosphate binding 32/1802 185/18639 0.172972972972973 1.78914719380868 0.000842105453814519 0.0466366020374422 GO:0046966 nuclear thyroid hormone receptor binding 9/1802 28/18639 0.321428571428571 3.3246987474235 0.000909481654779363 0.0477340267002958 GO:0140104 molecular carrier activity 40/1802 249/18639 0.160642570281124 1.66160758461148 0.000944009126489082 0.0477340267002958 GO:0043130 ubiquitin binding 20/1802 100/18639 0.2 2.06870144284129 0.00127867773630643 0.0616895863496233 GO:0005543 phospholipid binding 69/1802 497/18639 0.138832997987928 1.43602011625804 0.00135103201820133 0.0616895863496233 GO:0016922 nuclear receptor binding 25/1802 137/18639 0.182481751824818 1.88750131646103 0.00137913090721428 0.0616895863496233 GO:0000049 tRNA binding 17/1802 80/18639 0.2125 2.19799528301887 0.00144208758189329 0.0621165873237739 GO:0008173 RNA methyltransferase activity 15/1802 67/18639 0.223880597014925 2.31571057034472 0.00155204258550841 0.0644651973909388 GO:0042974 nuclear retinoic acid receptor binding 8/1802 25/18639 0.32 3.30992230854606 0.00180592835383059 0.0704211138446858 GO:0030145 manganese ion binding 15/1802 68/18639 0.220588235294118 2.28165600313377 0.00181653776039602 0.0704211138446858 GO:0000339 RNA cap binding 7/1802 20/18639 0.35 3.62022752497225 0.00194828241413977 0.073092014440147 GO:0045296 cadherin binding 49/1802 334/18639 0.146706586826347 1.51746063920993 0.0020746965267414 0.0754022518937578 GO:0008168 methyltransferase activity 33/1802 204/18639 0.161764705882353 1.6732144022981 0.00223999250571387 0.0789427661862192 GO:0052742 phosphatidylinositol kinase activity 8/1802 26/18639 0.307692307692308 3.18261760437121 0.00239012631312828 0.0817563794755351 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 28/1802 167/18639 0.167664670658683 1.73424073052563 0.0027486913025822 0.0875970770522055 GO:0016741 transferase activity, transferring one-carbon groups 34/1802 215/18639 0.158139534883721 1.63571741992102 0.0028365722060983 0.0875970770522055 GO:0003743 translation initiation factor activity 12/1802 51/18639 0.235294117647059 2.43376640334269 0.00286215728975392 0.0875970770522055 GO:0005048 signal sequence binding 12/1802 51/18639 0.235294117647059 2.43376640334269 0.00286215728975392 0.0875970770522055 GO:0070063 RNA polymerase binding 13/1802 59/18639 0.220338983050847 2.27907786075735 0.00360959293670155 0.107639912445741 GO:0005049 nuclear export signal receptor activity 5/1802 12/18639 0.416666666666667 4.30979467258602 0.00371989126795762 0.108155838615868 GO:0004177 aminopeptidase activity 10/1802 40/18639 0.25 2.58587680355161 0.00393563818809583 0.111637736896474 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 13/1802 60/18639 0.216666666666667 2.24109322974473 0.00420862564745784 0.116538848285559 GO:0004674 protein serine/threonine kinase activity 59/1802 433/18639 0.136258660508083 1.40939243796346 0.00437625757020174 0.118362501259177 GO:0019887 protein kinase regulator activity 38/1802 255/18639 0.149019607843137 1.5413853887837 0.00474449117593645 0.125405528127593 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 8/1802 29/18639 0.275862068965517 2.85338130047074 0.00505539746678577 0.127813635953736 GO:0097472 cyclin-dependent protein kinase activity 8/1802 29/18639 0.275862068965517 2.85338130047074 0.00505539746678577 0.127813635953736 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 11/1802 48/18639 0.229166666666667 2.37038706992231 0.00523397294103447 0.129512990009002 GO:0004535 poly(A)-specific ribonuclease activity 5/1802 13/18639 0.384615384615385 3.97827200546401 0.00556782473537733 0.130444887336012 GO:0031492 nucleosomal DNA binding 10/1802 42/18639 0.238095238095238 2.46273981290629 0.00572028310759813 0.130444887336012 GO:0035198 miRNA binding 10/1802 42/18639 0.238095238095238 2.46273981290629 0.00572028310759813 0.130444887336012 GO:0043175 RNA polymerase core enzyme binding 10/1802 42/18639 0.238095238095238 2.46273981290629 0.00572028310759813 0.130444887336012 GO:0000993 RNA polymerase II complex binding 9/1802 36/18639 0.25 2.58587680355161 0.00611609700201353 0.134207939874372 GO:0005484 SNAP receptor activity 9/1802 36/18639 0.25 2.58587680355161 0.00611609700201353 0.134207939874372 GO:0031625 ubiquitin protein ligase binding 43/1802 302/18639 0.142384105960265 1.47275102718833 0.00641344180044527 0.138126533591071 GO:0004712 protein serine/threonine/tyrosine kinase activity 10/1802 43/18639 0.232558139534884 2.4054667940015 0.00682158005113054 0.141669599990443 GO:0048156 tau protein binding 10/1802 43/18639 0.232558139534884 2.4054667940015 0.00682158005113054 0.141669599990443 GO:0004386 helicase activity 25/1802 155/18639 0.161290322580645 1.66830761519459 0.00742708722471813 0.151538639339424 GO:0009055 electron transfer activity 20/1802 116/18639 0.172413793103448 1.78336331279421 0.00758132025509978 0.15201854235657 GO:0019211 phosphatase activator activity 7/1802 25/18639 0.28 2.8961820199778 0.00786401237297668 0.155014345589354 GO:0140713 histone chaperone activity 26/1802 164/18639 0.158536585365854 1.63982431444736 0.00803570698078984 0.155758786977643 GO:0019843 rRNA binding 13/1802 65/18639 0.2 2.06870144284129 0.0085112180696214 0.16227125598311 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 9/1802 38/18639 0.236842105263158 2.44977802441731 0.00888651872440581 0.166693891556193 GO:0022884 macromolecule transmembrane transporter activity 8/1802 32/18639 0.25 2.58587680355161 0.00954997390771423 0.173540932104245 GO:0030515 snoRNA binding 8/1802 32/18639 0.25 2.58587680355161 0.00954997390771423 0.173540932104245 GO:0050681 nuclear androgen receptor binding 7/1802 26/18639 0.269230769230769 2.78479040382481 0.00988070723713135 0.176788654104365 GO:0004559 alpha-mannosidase activity 5/1802 15/18639 0.333333333333333 3.44783573806881 0.011030173445414 0.189638781934966 GO:0140296 general transcription initiation factor binding 11/1802 53/18639 0.207547169811321 2.14676564823152 0.0113059258040443 0.189638781934966 GO:0042975 peroxisome proliferator activated receptor binding 4/1802 10/18639 0.4 4.13740288568258 0.0113459000305383 0.189638781934966 GO:1905394 retromer complex binding 4/1802 10/18639 0.4 4.13740288568258 0.0113459000305383 0.189638781934966 GO:0008094 ATP-dependent activity, acting on DNA 31/1802 210/18639 0.147619047619048 1.5268986840019 0.011414200116464 0.189638781934966 GO:0044389 ubiquitin-like protein ligase binding 44/1802 322/18639 0.136645962732919 1.41339850132013 0.0119539544364997 0.194690636823218 GO:0008320 protein transmembrane transporter activity 7/1802 27/18639 0.259259259259259 2.68165001849797 0.0122495788050118 0.194690636823218 GO:0010314 phosphatidylinositol-5-phosphate binding 6/1802 21/18639 0.285714285714286 2.95528777548755 0.0122906267017028 0.194690636823218 GO:0004532 RNA exonuclease activity 9/1802 40/18639 0.225 2.32728912319645 0.0125149167314409 0.194690636823218 GO:0000149 SNARE binding 18/1802 106/18639 0.169811320754717 1.75644462128034 0.0127189635787198 0.194690636823218 GO:0015631 tubulin binding 51/1802 385/18639 0.132467532467532 1.37017887772605 0.0128619309701275 0.194690636823218 GO:0051287 NAD binding 11/1802 54/18639 0.203703703703704 2.10701072881983 0.0129911621184401 0.194690636823218 GO:0051020 GTPase binding 43/1802 315/18639 0.136507936507936 1.41197082606628 0.0130574975685392 0.194690636823218 GO:0003714 transcription corepressor activity 30/1802 204/18639 0.147058823529412 1.52110400208918 0.0133185215157751 0.196068867377803 GO:0008175 tRNA methyltransferase activity 8/1802 34/18639 0.235294117647059 2.43376640334269 0.0138693160042407 0.197404072436063 GO:0005525 GTP binding 50/1802 378/18639 0.132275132275132 1.36818878494794 0.0140187060599602 0.197404072436063 GO:0003713 transcription coactivator activity 36/1802 256/18639 0.140625 1.45455570199778 0.0142111739180877 0.197404072436063 GO:0061650 ubiquitin-like protein conjugating enzyme activity 9/1802 41/18639 0.219512195121951 2.27052597385019 0.0146952258152545 0.197404072436063 GO:0004708 MAP kinase kinase activity 5/1802 16/18639 0.3125 3.23234600443951 0.0147887417652188 0.197404072436063 GO:0008142 oxysterol binding 5/1802 16/18639 0.3125 3.23234600443951 0.0147887417652188 0.197404072436063 GO:0015923 mannosidase activity 5/1802 16/18639 0.3125 3.23234600443951 0.0147887417652188 0.197404072436063 GO:0003724 RNA helicase activity 14/1802 77/18639 0.181818181818182 1.88063767531026 0.0149051736041124 0.197404072436063 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 7/1802 28/18639 0.25 2.58587680355161 0.0150015346738324 0.197404072436063 GO:0031267 small GTPase binding 39/1802 283/18639 0.137809187279152 1.42543032280583 0.015106588518323 0.197404072436063 GO:0140097 catalytic activity, acting on DNA 45/1802 336/18639 0.133928571428571 1.38529114475979 0.0155343251529865 0.198688809826632 GO:0070034 telomerase RNA binding 6/1802 22/18639 0.272727272727273 2.82095651296539 0.0155465878712154 0.198688809826632 GO:0048407 platelet-derived growth factor binding 4/1802 11/18639 0.363636363636364 3.76127535062052 0.0164827598988908 0.203501570792554 GO:0180030 inositol phosphate kinase activity 4/1802 11/18639 0.363636363636364 3.76127535062052 0.0164827598988908 0.203501570792554 GO:0019208 phosphatase regulator activity 19/1802 117/18639 0.162393162393162 1.67971484675147 0.016797002680109 0.203501570792554 GO:0008186 ATP-dependent activity, acting on RNA 14/1802 79/18639 0.177215189873418 1.83302659492266 0.0184350597267527 0.203501570792554 GO:0019207 kinase regulator activity 39/1802 287/18639 0.13588850174216 1.40556369809774 0.018616776272722 0.203501570792554 GO:0017134 fibroblast growth factor binding 6/1802 23/18639 0.260869565217391 2.69830622979298 0.0193536949185762 0.203501570792554 GO:0140102 catalytic activity, acting on a rRNA 6/1802 23/18639 0.260869565217391 2.69830622979298 0.0193536949185762 0.203501570792554 GO:0004676 3-phosphoinositide-dependent protein kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0004711 ribosomal protein S6 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0035175 histone H3S10 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0035979 histone H2AXS139 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0044022 histone H3S28 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0044023 histone H4S1 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0044024 histone H2AS1 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0044025 histone H2BS14 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0072354 histone H3T3 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0072371 histone H2AS121 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0072518 Rho-dependent protein serine/threonine kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0140823 histone H2BS36 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0140855 histone H3S57 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0140995 histone H2A kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0140997 histone H4 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0140998 histone H2B kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:1990244 histone H2AT120 kinase activity 34/1802 245/18639 0.138775510204082 1.4354254909511 0.0201226832683953 0.203501570792554 GO:0004197 cysteine-type endopeptidase activity 15/1802 88/18639 0.170454545454545 1.76309782060337 0.0209942483000145 0.209378408435415 GO:0004677 DNA-dependent protein kinase activity 34/1802 246/18639 0.138211382113821 1.42959042797975 0.0212529044521754 0.209378408435415 GO:0140857 histone H3T45 kinase activity 34/1802 246/18639 0.138211382113821 1.42959042797975 0.0212529044521754 0.209378408435415 GO:0001968 fibronectin binding 7/1802 30/18639 0.233333333333333 2.41348501664817 0.0217715898823492 0.209378408435415 GO:0015215 nucleotide transmembrane transporter activity 7/1802 30/18639 0.233333333333333 2.41348501664817 0.0217715898823492 0.209378408435415 GO:0035402 histone H3T11 kinase activity 34/1802 247/18639 0.137651821862348 1.42380261248186 0.0224327578017644 0.209378408435415 GO:0035403 histone H3T6 kinase activity 34/1802 247/18639 0.137651821862348 1.42380261248186 0.0224327578017644 0.209378408435415 GO:0000340 RNA 7-methylguanosine cap binding 4/1802 12/18639 0.333333333333333 3.44783573806881 0.0228641942143574 0.209378408435415 GO:0005078 MAP-kinase scaffold activity 4/1802 12/18639 0.333333333333333 3.44783573806881 0.0228641942143574 0.209378408435415 GO:0035259 nuclear glucocorticoid receptor binding 4/1802 12/18639 0.333333333333333 3.44783573806881 0.0228641942143574 0.209378408435415 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1802 12/18639 0.333333333333333 3.44783573806881 0.0228641942143574 0.209378408435415 GO:1990459 transferrin receptor binding 4/1802 12/18639 0.333333333333333 3.44783573806881 0.0228641942143574 0.209378408435415 GO:0004679 AMP-activated protein kinase activity 34/1802 248/18639 0.137096774193548 1.4180614729154 0.0236636436589436 0.212462299619075 GO:0016887 ATP hydrolysis activity 53/1802 417/18639 0.127098321342926 1.31464240372408 0.0236956819849748 0.212462299619075 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/1802 24/18639 0.25 2.58587680355161 0.023749010275563 0.212462299619075 GO:0140597 protein carrier chaperone 27/1802 188/18639 0.143617021276596 1.48550369565731 0.0239745766207658 0.212842997022524 GO:0003684 damaged DNA binding 13/1802 74/18639 0.175675675675676 1.81710261871194 0.0241751160699407 0.212997424161675 GO:0031593 polyubiquitin modification-dependent protein binding 11/1802 59/18639 0.186440677966102 1.92845049756391 0.0244001288801692 0.21336353298975 GO:0008327 methyl-CpG binding 7/1802 31/18639 0.225806451612903 2.33563066127242 0.0258435966003751 0.222865312318815 GO:0008017 microtubule binding 37/1802 276/18639 0.134057971014493 1.38662959031028 0.0258700061591058 0.222865312318815 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 45/1802 349/18639 0.128939828080229 1.33369004194639 0.0281416154580108 0.240652196894607 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/1802 68/18639 0.176470588235294 1.82532480250702 0.0286581928144793 0.240716742519291 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 6/1802 25/18639 0.24 2.48244173140954 0.0287653254026956 0.240716742519291 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 33/1802 243/18639 0.135802469135802 1.40467381921322 0.0287701007826151 0.240716742519291 GO:0030291 protein serine/threonine kinase inhibitor activity 9/1802 46/18639 0.195652173913043 2.02372967234474 0.0299384736880507 0.245736176078801 GO:0004527 exonuclease activity 14/1802 84/18639 0.166666666666667 1.72391786903441 0.0300039011205415 0.245736176078801 GO:0004860 protein kinase inhibitor activity 14/1802 84/18639 0.166666666666667 1.72391786903441 0.0300039011205415 0.245736176078801 GO:0140852 histone ubiquitin ligase activity 4/1802 13/18639 0.307692307692308 3.18261760437121 0.0305514695383486 0.247122263519079 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/1802 39/18639 0.205128205128205 2.12174506958081 0.030598113453781 0.247122263519079 GO:0017069 snRNA binding 10/1802 54/18639 0.185185185185185 1.91546429892712 0.0323740300143154 0.25966204763206 GO:0005112 Notch binding 6/1802 26/18639 0.230769230769231 2.38696320327841 0.0344307108523648 0.272400794022451 GO:0070006 metalloaminopeptidase activity 6/1802 26/18639 0.230769230769231 2.38696320327841 0.0344307108523648 0.272400794022451 GO:0019001 guanyl nucleotide binding 50/1802 400/18639 0.125 1.2929384017758 0.035505261534188 0.27713167224336 GO:0032561 guanyl ribonucleotide binding 50/1802 400/18639 0.125 1.2929384017758 0.035505261534188 0.27713167224336 GO:0031418 L-ascorbic acid binding 5/1802 20/18639 0.25 2.58587680355161 0.0379925044573211 0.290102005514922 GO:0052745 inositol phosphate phosphatase activity 5/1802 20/18639 0.25 2.58587680355161 0.0379925044573211 0.290102005514922 GO:0061608 nuclear import signal receptor activity 5/1802 20/18639 0.25 2.58587680355161 0.0379925044573211 0.290102005514922 GO:0061775 cohesin loader activity 22/1802 153/18639 0.143790849673203 1.48730169093164 0.038164752230252 0.290102005514922 GO:0001727 lipid kinase activity 8/1802 41/18639 0.195121951219512 2.01824531008906 0.0400701094389992 0.300655079210039 GO:0140318 protein transporter activity 8/1802 41/18639 0.195121951219512 2.01824531008906 0.0400701094389992 0.300655079210039 GO:0008266 poly(U) RNA binding 6/1802 27/18639 0.222222222222222 2.29855715871254 0.0407681771516085 0.302700634740822 GO:0016755 aminoacyltransferase activity 60/1802 496/18639 0.120967741935484 1.25123071139594 0.0408632843115296 0.302700634740822 GO:0016853 isomerase activity 25/1802 180/18639 0.138888888888889 1.43659822419534 0.0411493963038148 0.302890809502131 GO:0035591 signaling adaptor activity 19/1802 129/18639 0.147286821705426 1.52346230286762 0.0416890804144386 0.304933336616303 GO:0005518 collagen binding 12/1802 72/18639 0.166666666666667 1.72391786903441 0.042443841514434 0.308108005884165 GO:0140297 DNA-binding transcription factor binding 59/1802 488/18639 0.120901639344262 1.25054697876676 0.0426529569624683 0.308108005884165 GO:0019787 ubiquitin-like protein transferase activity 58/1802 479/18639 0.121085594989562 1.25244972531101 0.0430553930985782 0.309095198602756 GO:0016504 peptidase activator activity 10/1802 57/18639 0.175438596491228 1.81465038845727 0.0449975464057037 0.312026682867629 GO:0140030 modification-dependent protein binding 24/1802 173/18639 0.138728323699422 1.43493741699974 0.0452028470231085 0.312026682867629 GO:0016859 cis-trans isomerase activity 8/1802 42/18639 0.19047619047619 1.97019185032504 0.0454647381392819 0.312026682867629 GO:0048487 beta-tubulin binding 8/1802 42/18639 0.19047619047619 1.97019185032504 0.0454647381392819 0.312026682867629 GO:0019200 carbohydrate kinase activity 5/1802 21/18639 0.238095238095238 2.46273981290629 0.0460243412559519 0.312026682867629 GO:0051010 microtubule plus-end binding 5/1802 21/18639 0.238095238095238 2.46273981290629 0.0460243412559519 0.312026682867629 GO:0072542 protein phosphatase activator activity 5/1802 21/18639 0.238095238095238 2.46273981290629 0.0460243412559519 0.312026682867629 GO:0140312 cargo adaptor activity 5/1802 21/18639 0.238095238095238 2.46273981290629 0.0460243412559519 0.312026682867629 GO:0140101 catalytic activity, acting on a tRNA 20/1802 139/18639 0.143884892086331 1.48827441931028 0.0461376484967057 0.312026682867629 GO:0003727 single-stranded RNA binding 14/1802 89/18639 0.157303370786517 1.62706855054933 0.0461466805272848 0.312026682867629 GO:0000175 3'-5'-RNA exonuclease activity 7/1802 35/18639 0.2 2.06870144284129 0.0472284627726271 0.315670702325088 GO:0061631 ubiquitin conjugating enzyme activity 7/1802 35/18639 0.2 2.06870144284129 0.0472284627726271 0.315670702325088 GO:0019789 SUMO transferase activity 6/1802 28/18639 0.214285714285714 2.21646583161567 0.0477954432819112 0.31583011668672 GO:0097718 disordered domain specific binding 6/1802 28/18639 0.214285714285714 2.21646583161567 0.0477954432819112 0.31583011668672 GO:0008408 3'-5' exonuclease activity 10/1802 58/18639 0.172413793103448 1.78336331279421 0.0498547028700816 0.322978894672729 GO:0061980 regulatory RNA binding 10/1802 58/18639 0.172413793103448 1.78336331279421 0.0498547028700816 0.322978894672729 GO:0042809 nuclear vitamin D receptor binding 4/1802 15/18639 0.266666666666667 2.75826859045505 0.0499620846734695 0.322978894672729 GO:0019210 kinase inhibitor activity 14/1802 90/18639 0.155555555555556 1.60899001109878 0.0499881350310328 0.322978894672729 GO:0008200 ion channel inhibitor activity 8/1802 43/18639 0.186046511627907 1.9243734352012 0.0513138070891676 0.329021263188677 GO:0140658 ATP-dependent chromatin remodeler activity 22/1802 158/18639 0.139240506329114 1.44023518172495 0.0515944146417419 0.329021263188677 GO:0019888 protein phosphatase regulator activity 16/1802 107/18639 0.149532710280374 1.54669266754489 0.0517720474320962 0.329021263188677 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 7/1802 36/18639 0.194444444444444 2.01123751387347 0.0539311748699181 0.336121550399432 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 7/1802 36/18639 0.194444444444444 2.01123751387347 0.0539311748699181 0.336121550399432 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 7/1802 36/18639 0.194444444444444 2.01123751387347 0.0539311748699181 0.336121550399432 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 14/1802 91/18639 0.153846153846154 1.59130880218561 0.0540453395741133 0.336121550399432 GO:0008649 rRNA methyltransferase activity 5/1802 22/18639 0.227272727272727 2.35079709413783 0.0549883863691096 0.336586807090918 GO:0050321 tau-protein kinase activity 5/1802 22/18639 0.227272727272727 2.35079709413783 0.0549883863691096 0.336586807090918 GO:0140035 ubiquitin-like protein reader activity 5/1802 22/18639 0.227272727272727 2.35079709413783 0.0549883863691096 0.336586807090918 GO:0000510 H3-H4 histone complex chaperone activity 21/1802 151/18639 0.139072847682119 1.43850100330023 0.0567751528567676 0.340358261713509 GO:0140584 chromatin extrusion motor activity 21/1802 151/18639 0.139072847682119 1.43850100330023 0.0567751528567676 0.340358261713509 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 21/1802 151/18639 0.139072847682119 1.43850100330023 0.0567751528567676 0.340358261713509 GO:0140849 ATP-dependent H2AZ histone chaperone activity 21/1802 151/18639 0.139072847682119 1.43850100330023 0.0567751528567676 0.340358261713509 GO:0016248 channel inhibitor activity 8/1802 44/18639 0.181818181818182 1.88063767531026 0.0576262016742143 0.343046861316533 GO:0003689 DNA clamp loader activity 22/1802 160/18639 0.1375 1.42223224195339 0.0578135725004647 0.343046861316533 GO:0015616 DNA translocase activity 21/1802 152/18639 0.138157894736842 1.4290371809101 0.0601339508605798 0.344582093109029 GO:0140674 ATP-dependent histone chaperone activity 21/1802 152/18639 0.138157894736842 1.4290371809101 0.0601339508605798 0.344582093109029 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 10/1802 60/18639 0.166666666666667 1.72391786903441 0.0605881777799134 0.344582093109029 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 4/1802 16/18639 0.25 2.58587680355161 0.0616865323095531 0.344582093109029 GO:0043023 ribosomal large subunit binding 4/1802 16/18639 0.25 2.58587680355161 0.0616865323095531 0.344582093109029 GO:0008106 alcohol dehydrogenase (NADP+) activity 6/1802 30/18639 0.2 2.06870144284129 0.0639631116060368 0.344582093109029 GO:0008187 poly-pyrimidine tract binding 6/1802 30/18639 0.2 2.06870144284129 0.0639631116060368 0.344582093109029 GO:0016769 transferase activity, transferring nitrogenous groups 6/1802 30/18639 0.2 2.06870144284129 0.0639631116060368 0.344582093109029 GO:0051539 4 iron, 4 sulfur cluster binding 8/1802 45/18639 0.177777777777778 1.83884572697003 0.0644086116836302 0.344582093109029 GO:0141110 transporter inhibitor activity 8/1802 45/18639 0.177777777777778 1.83884572697003 0.0644086116836302 0.344582093109029 GO:0001094 TFIID-class transcription factor complex binding 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0005522 profilin binding 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0008239 dipeptidyl-peptidase activity 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0008641 ubiquitin-like modifier activating enzyme activity 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0016427 tRNA (cytidine) methyltransferase activity 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0051880 G-quadruplex DNA binding 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0070513 death domain binding 3/1802 10/18639 0.3 3.10305216426193 0.0645390976333945 0.344582093109029 GO:0000295 adenine nucleotide transmembrane transporter activity 5/1802 23/18639 0.217391304347826 2.24858852482749 0.0648869117720356 0.344582093109029 GO:0005158 insulin receptor binding 5/1802 23/18639 0.217391304347826 2.24858852482749 0.0648869117720356 0.344582093109029 GO:0008171 O-methyltransferase activity 5/1802 23/18639 0.217391304347826 2.24858852482749 0.0648869117720356 0.344582093109029 GO:0016836 hydro-lyase activity 10/1802 61/18639 0.163934426229508 1.69565692036171 0.066475758048991 0.351415030049894 GO:0031490 chromatin DNA binding 18/1802 128/18639 0.140625 1.45455570199778 0.0674732268359054 0.355074039864968 GO:0042162 telomeric DNA binding 7/1802 38/18639 0.184210526315789 1.90538290788013 0.0690350775604049 0.361656735147526 GO:0008276 protein methyltransferase activity 14/1802 95/18639 0.147368421052632 1.52430632630411 0.0725084216863605 0.377537147720923 GO:0140463 chromatin-protein adaptor activity 9/1802 54/18639 0.166666666666667 1.72391786903441 0.0727156673168416 0.377537147720923 GO:0060229 lipase activator activity 5/1802 24/18639 0.208333333333333 2.15489733629301 0.0757126753237388 0.391350406228925 GO:0030295 protein kinase activator activity 19/1802 139/18639 0.136690647482014 1.41386069834477 0.0772494675771603 0.39752712739928 GO:0019206 nucleoside kinase activity 3/1802 11/18639 0.272727272727273 2.82095651296539 0.0825602242838334 0.415660349965793 GO:0035252 UDP-xylosyltransferase activity 3/1802 11/18639 0.272727272727273 2.82095651296539 0.0825602242838334 0.415660349965793 GO:0042285 xylosyltransferase activity 3/1802 11/18639 0.272727272727273 2.82095651296539 0.0825602242838334 0.415660349965793 GO:0050786 RAGE receptor binding 3/1802 11/18639 0.272727272727273 2.82095651296539 0.0825602242838334 0.415660349965793 GO:0070990 snRNP binding 3/1802 11/18639 0.272727272727273 2.82095651296539 0.0825602242838334 0.415660349965793 GO:0030331 nuclear estrogen receptor binding 7/1802 40/18639 0.175 1.81011376248613 0.0864210348457148 0.429612611354382 GO:0008139 nuclear localization sequence binding 5/1802 25/18639 0.2 2.06870144284129 0.0874495128039998 0.429612611354382 GO:0008483 transaminase activity 5/1802 25/18639 0.2 2.06870144284129 0.0874495128039998 0.429612611354382 GO:0017025 TBP-class protein binding 5/1802 25/18639 0.2 2.06870144284129 0.0874495128039998 0.429612611354382 GO:0140693 molecular condensate scaffold activity 8/1802 48/18639 0.166666666666667 1.72391786903441 0.0876090443190039 0.429612611354382 GO:0003746 translation elongation factor activity 4/1802 18/18639 0.222222222222222 2.29855715871254 0.0890254852419657 0.429612611354382 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/1802 18/18639 0.222222222222222 2.29855715871254 0.0890254852419657 0.429612611354382 GO:0008409 5'-3' exonuclease activity 4/1802 18/18639 0.222222222222222 2.29855715871254 0.0890254852419657 0.429612611354382 GO:0035615 clathrin adaptor activity 4/1802 18/18639 0.222222222222222 2.29855715871254 0.0890254852419657 0.429612611354382 GO:0070628 proteasome binding 4/1802 18/18639 0.222222222222222 2.29855715871254 0.0890254852419657 0.429612611354382 GO:0043539 protein serine/threonine kinase activator activity 11/1802 73/18639 0.150684931506849 1.5586106761133 0.0913114332412079 0.438823127518697 GO:0015932 nucleobase-containing compound transmembrane transporter activity 9/1802 57/18639 0.157894736842105 1.63318534961154 0.0953353497638027 0.455534627083473 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 7/1802 41/18639 0.170731707317073 1.76596464632793 0.0959638724294504 0.455534627083473 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/1802 41/18639 0.170731707317073 1.76596464632793 0.0959638724294504 0.455534627083473 GO:0008198 ferrous iron binding 5/1802 26/18639 0.192307692307692 1.98913600273201 0.100073037078199 0.467409406112229 GO:0015216 purine nucleotide transmembrane transporter activity 5/1802 26/18639 0.192307692307692 1.98913600273201 0.100073037078199 0.467409406112229 GO:0034237 protein kinase A regulatory subunit binding 5/1802 26/18639 0.192307692307692 1.98913600273201 0.100073037078199 0.467409406112229 GO:0050750 low-density lipoprotein particle receptor binding 5/1802 26/18639 0.192307692307692 1.98913600273201 0.100073037078199 0.467409406112229 GO:0004300 enoyl-CoA hydratase activity 3/1802 12/18639 0.25 2.58587680355161 0.102458900973659 0.47473984793771 GO:0031543 peptidyl-proline dioxygenase activity 3/1802 12/18639 0.25 2.58587680355161 0.102458900973659 0.47473984793771 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/1802 19/18639 0.210526315789474 2.17758046614872 0.104530777807134 0.476871989191259 GO:0031420 alkali metal ion binding 4/1802 19/18639 0.210526315789474 2.17758046614872 0.104530777807134 0.476871989191259 GO:0016831 carboxy-lyase activity 6/1802 34/18639 0.176470588235294 1.82532480250702 0.104756627263273 0.476871989191259 GO:0030332 cyclin binding 6/1802 34/18639 0.176470588235294 1.82532480250702 0.104756627263273 0.476871989191259 GO:0015605 organophosphate ester transmembrane transporter activity 8/1802 50/18639 0.16 1.65496115427303 0.10544718065881 0.476871989191259 GO:0019003 GDP binding 11/1802 75/18639 0.146666666666667 1.51704772475028 0.105764279850302 0.476871989191259 GO:0042056 chemoattractant activity 7/1802 42/18639 0.166666666666667 1.72391786903441 0.106063699287484 0.476871989191259 GO:0008194 UDP-glycosyltransferase activity 19/1802 145/18639 0.131034482758621 1.3553561177236 0.106199350989283 0.476871989191259 GO:0050840 extracellular matrix binding 10/1802 67/18639 0.149253731343284 1.54380704689648 0.109261522539128 0.488735195050024 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 17/1802 128/18639 0.1328125 1.37374705188679 0.110833693282217 0.493868142862906 GO:0051536 iron-sulfur cluster binding 11/1802 76/18639 0.144736842105263 1.49708657047725 0.113462731440355 0.499351289786688 GO:0005385 zinc ion transmembrane transporter activity 5/1802 27/18639 0.185185185185185 1.91546429892712 0.113551414334242 0.499351289786688 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 5/1802 27/18639 0.185185185185185 1.91546429892712 0.113551414334242 0.499351289786688 GO:0008238 exopeptidase activity 14/1802 102/18639 0.137254901960784 1.41969706861657 0.113781678240303 0.499351289786688 GO:0043015 gamma-tubulin binding 6/1802 35/18639 0.171428571428571 1.77317266529253 0.116659006123407 0.510054226020761 GO:1990841 promoter-specific chromatin binding 10/1802 68/18639 0.147058823529412 1.52110400208918 0.117632378061514 0.51238372915933 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/1802 20/18639 0.2 2.06870144284129 0.121165346144588 0.515172159500517 GO:0016004 phospholipase activator activity 4/1802 20/18639 0.2 2.06870144284129 0.121165346144588 0.515172159500517 GO:0051540 metal cluster binding 11/1802 77/18639 0.142857142857143 1.47764388774378 0.121472311172271 0.515172159500517 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 9/1802 60/18639 0.15 1.55152608213097 0.121595067807349 0.515172159500517 GO:0098531 ligand-modulated transcription factor activity 9/1802 60/18639 0.15 1.55152608213097 0.121595067807349 0.515172159500517 GO:0019209 kinase activator activity 19/1802 148/18639 0.128378378378378 1.32788268290488 0.122906417067031 0.515172159500517 GO:0016798 hydrolase activity, acting on glycosyl bonds 17/1802 130/18639 0.130769230769231 1.35261248185776 0.122914745655011 0.515172159500517 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/1802 13/18639 0.230769230769231 2.38696320327841 0.124031130404252 0.515172159500517 GO:0005172 vascular endothelial growth factor receptor binding 3/1802 13/18639 0.230769230769231 2.38696320327841 0.124031130404252 0.515172159500517 GO:0031994 insulin-like growth factor I binding 3/1802 13/18639 0.230769230769231 2.38696320327841 0.124031130404252 0.515172159500517 GO:0046975 histone H3K36 methyltransferase activity 3/1802 13/18639 0.230769230769231 2.38696320327841 0.124031130404252 0.515172159500517 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/1802 13/18639 0.230769230769231 2.38696320327841 0.124031130404252 0.515172159500517 GO:0140666 annealing activity 3/1802 13/18639 0.230769230769231 2.38696320327841 0.124031130404252 0.515172159500517 GO:0002039 p53 binding 10/1802 69/18639 0.144927536231884 1.49905901655166 0.126349187089521 0.521870481062491 GO:0051019 mitogen-activated protein kinase binding 5/1802 28/18639 0.178571428571429 1.84705485967972 0.127846190649966 0.521870481062491 GO:0051537 2 iron, 2 sulfur cluster binding 5/1802 28/18639 0.178571428571429 1.84705485967972 0.127846190649966 0.521870481062491 GO:0003954 NADH dehydrogenase activity 7/1802 44/18639 0.159090909090909 1.64555796589648 0.127887435170086 0.521870481062491 GO:0043014 alpha-tubulin binding 7/1802 44/18639 0.159090909090909 1.64555796589648 0.127887435170086 0.521870481062491 GO:0141003 histone H2AX kinase activity 41/1802 354/18639 0.115819209039548 1.19797682424425 0.128407682786194 0.522161311469733 GO:0004033 aldo-keto reductase (NADPH) activity 6/1802 36/18639 0.166666666666667 1.72391786903441 0.129204572374105 0.523571141711094 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 9/1802 61/18639 0.147540983606557 1.52609122832554 0.131134948342449 0.527716072395393 GO:0019905 syntaxin binding 9/1802 61/18639 0.147540983606557 1.52609122832554 0.131134948342449 0.527716072395393 GO:0016247 channel regulator activity 21/1802 168/18639 0.125 1.2929384017758 0.133313464861086 0.534632964253251 GO:0016407 acetyltransferase activity 13/1802 96/18639 0.135416666666667 1.40068326859046 0.13391498627544 0.535199756145487 GO:0051018 protein kinase A binding 8/1802 53/18639 0.150943396226415 1.56128410780475 0.135649221161511 0.540274124009716 GO:0008234 cysteine-type peptidase activity 23/1802 187/18639 0.122994652406417 1.27219607447459 0.136757026617924 0.542271278215403 GO:0005096 GTPase activator activity 32/1802 271/18639 0.118081180811808 1.22137354558895 0.137083195008881 0.542271278215403 GO:0140996 histone H3 kinase activity 41/1802 357/18639 0.11484593837535 1.18790979210774 0.140177574615115 0.552632268736878 GO:0141108 transporter regulator activity 21/1802 170/18639 0.123529411764706 1.27772736175491 0.145096709964616 0.566339374480095 GO:0008174 mRNA methyltransferase activity 3/1802 14/18639 0.214285714285714 2.21646583161567 0.147063190965597 0.566339374480095 GO:0008191 metalloendopeptidase inhibitor activity 3/1802 14/18639 0.214285714285714 2.21646583161567 0.147063190965597 0.566339374480095 GO:0016530 metallochaperone activity 3/1802 14/18639 0.214285714285714 2.21646583161567 0.147063190965597 0.566339374480095 GO:0030983 mismatched DNA binding 3/1802 14/18639 0.214285714285714 2.21646583161567 0.147063190965597 0.566339374480095 GO:0042043 neurexin family protein binding 3/1802 14/18639 0.214285714285714 2.21646583161567 0.147063190965597 0.566339374480095 GO:0046030 inositol trisphosphate phosphatase activity 3/1802 14/18639 0.214285714285714 2.21646583161567 0.147063190965597 0.566339374480095 GO:0008170 N-methyltransferase activity 13/1802 98/18639 0.13265306122449 1.37209789576208 0.14988093287515 0.57528556083762 GO:0030276 clathrin binding 7/1802 46/18639 0.152173913043478 1.57401196737924 0.151770849800506 0.580623349730227 GO:0035173 histone kinase activity 41/1802 360/18639 0.113888888888889 1.17801054384018 0.152583625663337 0.581818874250693 GO:0019903 protein phosphatase binding 18/1802 144/18639 0.125 1.2929384017758 0.15526190817992 0.586682041466676 GO:0043531 ADP binding 6/1802 38/18639 0.157894736842105 1.63318534961154 0.15611681798063 0.586682041466676 GO:0004407 histone deacetylase activity 4/1802 22/18639 0.181818181818182 1.88063767531026 0.157480515082276 0.586682041466676 GO:0033558 protein lysine deacetylase activity 4/1802 22/18639 0.181818181818182 1.88063767531026 0.157480515082276 0.586682041466676 GO:0034062 5'-3' RNA polymerase activity 4/1802 22/18639 0.181818181818182 1.88063767531026 0.157480515082276 0.586682041466676 GO:0046972 histone H4K16 acetyltransferase activity 4/1802 22/18639 0.181818181818182 1.88063767531026 0.157480515082276 0.586682041466676 GO:0097747 RNA polymerase activity 4/1802 22/18639 0.181818181818182 1.88063767531026 0.157480515082276 0.586682041466676 GO:0016829 lyase activity 24/1802 200/18639 0.12 1.24122086570477 0.15789465088484 0.586682041466676 GO:0070566 adenylyltransferase activity 5/1802 30/18639 0.166666666666667 1.72391786903441 0.158703152305918 0.587808172394213 GO:0004842 ubiquitin-protein transferase activity 50/1802 449/18639 0.111358574610245 1.15183821984481 0.162097613555469 0.598474681158764 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 27/1802 229/18639 0.117903930131004 1.21954015189334 0.162707824521295 0.59882658201983 GO:0019838 growth factor binding 17/1802 136/18639 0.125 1.2929384017758 0.163574376985058 0.600116720610798 GO:0140938 histone H3 methyltransferase activity 7/1802 47/18639 0.148936170212766 1.54052235105202 0.164435924935434 0.6002007161067 GO:0019783 ubiquitin-like protein peptidase activity 16/1802 127/18639 0.125984251968504 1.30311901911262 0.164765321879104 0.6002007161067 GO:0030695 GTPase regulator activity 54/1802 489/18639 0.110429447852761 1.14222779052586 0.16677131660136 0.6002007161067 GO:0019212 phosphatase inhibitor activity 8/1802 56/18639 0.142857142857143 1.47764388774378 0.169716742175274 0.6002007161067 GO:0060589 nucleoside-triphosphatase regulator activity 54/1802 490/18639 0.110204081632653 1.13989671340234 0.170642842872362 0.6002007161067 GO:0008252 nucleotidase activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0015929 hexosaminidase activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0016846 carbon-sulfur lyase activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0017081 chloride channel regulator activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0031005 filamin binding 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0050780 dopamine receptor binding 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0061578 K63-linked deubiquitinase activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0141050 histone H3K deacetylase activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0141051 histone H4K deacetylase activity 3/1802 15/18639 0.2 2.06870144284129 0.171338467538628 0.6002007161067 GO:0160215 deacylase activity 9/1802 65/18639 0.138461538461538 1.43217792196705 0.172991327512135 0.604170912602443 GO:0003678 DNA helicase activity 10/1802 74/18639 0.135135135135135 1.39777124516303 0.174881940532241 0.608103290580282 GO:0070325 lipoprotein particle receptor binding 5/1802 31/18639 0.161290322580645 1.66830761519459 0.175163028671019 0.608103290580282 GO:0052689 carboxylic ester hydrolase activity 12/1802 92/18639 0.130434782608696 1.34915311489649 0.175968747748234 0.609082302473799 GO:0009378 four-way junction helicase activity 7/1802 48/18639 0.145833333333333 1.50842813540511 0.177552709430922 0.609126256838236 GO:0036121 double-stranded DNA helicase activity 7/1802 48/18639 0.145833333333333 1.50842813540511 0.177552709430922 0.609126256838236 GO:0043138 3'-5' DNA helicase activity 7/1802 48/18639 0.145833333333333 1.50842813540511 0.177552709430922 0.609126256838236 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 6/1802 40/18639 0.15 1.55152608213097 0.185244663030513 0.627040274979311 GO:0050997 quaternary ammonium group binding 6/1802 40/18639 0.15 1.55152608213097 0.185244663030513 0.627040274979311 GO:0061791 GTPase motor activity 6/1802 40/18639 0.15 1.55152608213097 0.185244663030513 0.627040274979311 GO:1990606 membrane scission GTPase motor activity 6/1802 40/18639 0.15 1.55152608213097 0.185244663030513 0.627040274979311 GO:0051213 dioxygenase activity 12/1802 93/18639 0.129032258064516 1.33464609215567 0.185470210312023 0.627040274979311 GO:0016763 pentosyltransferase activity 7/1802 49/18639 0.142857142857143 1.47764388774378 0.191095945398324 0.640709536007205 GO:0031369 translation initiation factor binding 5/1802 32/18639 0.15625 1.61617300221976 0.192236363176259 0.640709536007205 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 8/1802 58/18639 0.137931034482759 1.42669065023537 0.194368115778486 0.640709536007205 GO:0016410 N-acyltransferase activity 12/1802 94/18639 0.127659574468085 1.32044772947316 0.195206189883487 0.640709536007205 GO:0042054 histone methyltransferase activity 9/1802 67/18639 0.134328358208955 1.38942634220683 0.195967338914897 0.640709536007205 GO:0000062 fatty-acyl-CoA binding 3/1802 16/18639 0.1875 1.93940760266371 0.196642760283799 0.640709536007205 GO:0004707 MAP kinase activity 3/1802 16/18639 0.1875 1.93940760266371 0.196642760283799 0.640709536007205 GO:0005521 lamin binding 3/1802 16/18639 0.1875 1.93940760266371 0.196642760283799 0.640709536007205 GO:0016722 oxidoreductase activity, acting on metal ions 3/1802 16/18639 0.1875 1.93940760266371 0.196642760283799 0.640709536007205 GO:0055102 lipase inhibitor activity 3/1802 16/18639 0.1875 1.93940760266371 0.196642760283799 0.640709536007205 GO:0003924 GTPase activity 37/1802 331/18639 0.11178247734139 1.15622286080253 0.197184717715719 0.640709536007205 GO:0005540 hyaluronic acid binding 4/1802 24/18639 0.166666666666667 1.72391786903441 0.197226151238675 0.640709536007205 GO:0043998 histone H2A acetyltransferase activity 4/1802 24/18639 0.166666666666667 1.72391786903441 0.197226151238675 0.640709536007205 GO:0048027 mRNA 5'-UTR binding 4/1802 24/18639 0.166666666666667 1.72391786903441 0.197226151238675 0.640709536007205 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 15/1802 122/18639 0.122950819672131 1.27174269027128 0.199032224101461 0.644775700919218 GO:0016877 ligase activity, forming carbon-sulfur bonds 6/1802 41/18639 0.146341463414634 1.5136839825668 0.200549941419267 0.647887727418355 GO:0099106 ion channel regulator activity 19/1802 160/18639 0.11875 1.22829148168701 0.204098496526579 0.657525073297539 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 16/1802 132/18639 0.121212121212121 1.25375845020684 0.205052185132636 0.658772627926121 GO:0001786 phosphatidylserine binding 8/1802 59/18639 0.135593220338983 1.40250945277375 0.207218952088329 0.662075937578921 GO:0004879 nuclear receptor activity 8/1802 59/18639 0.135593220338983 1.40250945277375 0.207218952088329 0.662075937578921 GO:0140223 general transcription initiation factor activity 9/1802 68/18639 0.132352941176471 1.36899360188026 0.20791673972304 0.662485392596975 GO:0019902 phosphatase binding 22/1802 190/18639 0.115789473684211 1.1976692563818 0.215912086030475 0.681788335711567 GO:0000030 mannosyltransferase activity 4/1802 25/18639 0.16 1.65496115427303 0.218135987130994 0.681788335711567 GO:0015296 monoatomic anion:monoatomic cation symporter activity 4/1802 25/18639 0.16 1.65496115427303 0.218135987130994 0.681788335711567 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 4/1802 25/18639 0.16 1.65496115427303 0.218135987130994 0.681788335711567 GO:0017056 structural constituent of nuclear pore 4/1802 25/18639 0.16 1.65496115427303 0.218135987130994 0.681788335711567 GO:0016830 carbon-carbon lyase activity 7/1802 51/18639 0.137254901960784 1.41969706861657 0.219352936469539 0.681788335711567 GO:0101005 deubiquitinase activity 14/1802 115/18639 0.121739130434783 1.25920957390339 0.219855571456582 0.681788335711567 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:0004659 prenyltransferase activity 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:0008484 sulfuric ester hydrolase activity 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:0046965 nuclear retinoid X receptor binding 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:0048038 quinone binding 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:0070403 NAD+ binding 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:0070492 oligosaccharide binding 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:1901567 fatty acid derivative binding 3/1802 17/18639 0.176470588235294 1.82532480250702 0.222768329811174 0.681788335711567 GO:0008376 acetylgalactosaminyltransferase activity 5/1802 34/18639 0.147058823529412 1.52110400208918 0.227986320470167 0.69354439769721 GO:0052866 phosphatidylinositol phosphate phosphatase activity 5/1802 34/18639 0.147058823529412 1.52110400208918 0.227986320470167 0.69354439769721 GO:0016651 oxidoreductase activity, acting on NAD(P)H 11/1802 88/18639 0.125 1.2929384017758 0.228398541975951 0.69354439769721 GO:0016835 carbon-oxygen lyase activity 10/1802 79/18639 0.126582278481013 1.30930471065904 0.23075592215273 0.695163165345571 GO:0046332 SMAD binding 10/1802 79/18639 0.126582278481013 1.30930471065904 0.23075592215273 0.695163165345571 GO:0015297 antiporter activity 16/1802 135/18639 0.118518518518519 1.22589715131336 0.231209116152649 0.695163165345571 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/1802 52/18639 0.134615384615385 1.39239520191241 0.234009070365865 0.695163165345571 GO:0004529 DNA exonuclease activity 4/1802 26/18639 0.153846153846154 1.59130880218561 0.239601978049685 0.695163165345571 GO:0070412 R-SMAD binding 4/1802 26/18639 0.153846153846154 1.59130880218561 0.239601978049685 0.695163165345571 GO:0016779 nucleotidyltransferase activity 16/1802 136/18639 0.117647058823529 1.21688320167135 0.240227081374994 0.695163165345571 GO:0008237 metallopeptidase activity 21/1802 184/18639 0.114130434782609 1.18050897553443 0.242723533649045 0.695163165345571 GO:0010485 histone H4 acetyltransferase activity 5/1802 35/18639 0.142857142857143 1.47764388774378 0.246540872861294 0.695163165345571 GO:0140566 histone reader activity 5/1802 35/18639 0.142857142857143 1.47764388774378 0.246540872861294 0.695163165345571 GO:0001046 core promoter sequence-specific DNA binding 6/1802 44/18639 0.136363636363636 1.4104782564827 0.24895649300496 0.695163165345571 GO:0004864 protein phosphatase inhibitor activity 7/1802 53/18639 0.132075471698113 1.36612359432915 0.248976873505658 0.695163165345571 GO:0005246 calcium channel regulator activity 7/1802 53/18639 0.132075471698113 1.36612359432915 0.248976873505658 0.695163165345571 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/1802 53/18639 0.132075471698113 1.36612359432915 0.248976873505658 0.695163165345571 GO:1901505 carbohydrate derivative transmembrane transporter activity 7/1802 53/18639 0.132075471698113 1.36612359432915 0.248976873505658 0.695163165345571 GO:0000400 four-way junction DNA binding 3/1802 18/18639 0.166666666666667 1.72391786903441 0.249516898725016 0.695163165345571 GO:0015078 proton transmembrane transporter activity 21/1802 185/18639 0.113513513513514 1.17412784593695 0.250599700444378 0.695163165345571 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0004090 carbonyl reductase (NADPH) activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0005031 tumor necrosis factor receptor activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0005131 growth hormone receptor binding 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0005381 iron ion transmembrane transporter activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0005528 FK506 binding 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0008140 cAMP response element binding protein binding 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0030957 Tat protein binding 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0097177 mitochondrial ribosome binding 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0099122 RNA polymerase II C-terminal domain binding 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0140940 histone H2A methyltransferase activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0140999 histone H3K4 trimethyltransferase activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0141109 transporter activator activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:1990259 histone H2AQ104 methyltransferase activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:1990757 ubiquitin ligase activator activity 2/1802 10/18639 0.2 2.06870144284129 0.251047746728409 0.695163165345571 GO:0030971 receptor tyrosine kinase binding 10/1802 81/18639 0.123456790123457 1.27697619928475 0.254807471460836 0.703898074368057 GO:0004683 calcium/calmodulin-dependent protein kinase activity 4/1802 27/18639 0.148148148148148 1.53237143914169 0.261523815217588 0.720739803549892 GO:0046915 transition metal ion transmembrane transporter activity 6/1802 45/18639 0.133333333333333 1.37913429522752 0.265783506905041 0.730747561537973 GO:1902936 phosphatidylinositol bisphosphate binding 13/1802 111/18639 0.117117117117117 1.21140174580796 0.274725420941027 0.742285826502543 GO:0004536 DNA nuclease activity 8/1802 64/18639 0.125 1.2929384017758 0.275848504424744 0.742285826502543 GO:0003756 protein disulfide isomerase activity 3/1802 19/18639 0.157894736842105 1.63318534961154 0.276701796397118 0.742285826502543 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/1802 19/18639 0.157894736842105 1.63318534961154 0.276701796397118 0.742285826502543 GO:0005520 insulin-like growth factor binding 3/1802 19/18639 0.157894736842105 1.63318534961154 0.276701796397118 0.742285826502543 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/1802 19/18639 0.157894736842105 1.63318534961154 0.276701796397118 0.742285826502543 GO:0070003 threonine-type peptidase activity 3/1802 19/18639 0.157894736842105 1.63318534961154 0.276701796397118 0.742285826502543 GO:0120227 acyl-CoA binding 3/1802 19/18639 0.157894736842105 1.63318534961154 0.276701796397118 0.742285826502543 GO:0140036 ubiquitin-modified protein reader activity 3/1802 19/18639 0.157894736842105 1.63318534961154 0.276701796397118 0.742285826502543 GO:0003697 single-stranded DNA binding 14/1802 121/18639 0.115702479338843 1.19676942974289 0.279515470832098 0.742285826502543 GO:0004540 RNA nuclease activity 14/1802 121/18639 0.115702479338843 1.19676942974289 0.279515470832098 0.742285826502543 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/1802 46/18639 0.130434782608696 1.34915311489649 0.282885405470721 0.742285826502543 GO:0050698 proteoglycan sulfotransferase activity 4/1802 28/18639 0.142857142857143 1.47764388774378 0.283803419312191 0.742285826502543 GO:0019213 deacetylase activity 5/1802 37/18639 0.135135135135135 1.39777124516303 0.284700303417927 0.742285826502543 GO:0035064 methylated histone binding 9/1802 74/18639 0.121621621621622 1.25799412064673 0.284982705949907 0.742285826502543 GO:0004518 nuclease activity 23/1802 209/18639 0.110047846889952 1.13828069821411 0.287127291731647 0.742285826502543 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0000099 sulfur amino acid transmembrane transporter activity 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0002162 dystroglycan binding 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0019215 intermediate filament binding 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0032050 clathrin heavy chain binding 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0032404 mismatch repair complex binding 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0043522 leucine zipper domain binding 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0048185 activin binding 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0097493 structural molecule activity conferring elasticity 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1802 11/18639 0.181818181818182 1.88063767531026 0.288489418382759 0.742285826502543 GO:0044183 protein folding chaperone 9/1802 75/18639 0.12 1.24122086570477 0.298546425835212 0.765691338480726 GO:0043495 protein-membrane adaptor activity 6/1802 47/18639 0.127659574468085 1.32044772947316 0.300219475792959 0.765691338480726 GO:0061749 forked DNA-dependent helicase activity 6/1802 47/18639 0.127659574468085 1.32044772947316 0.300219475792959 0.765691338480726 GO:1990518 single-stranded 3'-5' DNA helicase activity 6/1802 47/18639 0.127659574468085 1.32044772947316 0.300219475792959 0.765691338480726 GO:0030246 carbohydrate binding 30/1802 280/18639 0.107142857142857 1.10823291580783 0.30326434256447 0.767845342256131 GO:0016408 C-acyltransferase activity 3/1802 20/18639 0.15 1.55152608213097 0.304149405265212 0.767845342256131 GO:0030742 GTP-dependent protein binding 3/1802 20/18639 0.15 1.55152608213097 0.304149405265212 0.767845342256131 GO:0008235 metalloexopeptidase activity 8/1802 66/18639 0.121212121212121 1.25375845020684 0.304900366392236 0.767845342256131 GO:0016417 S-acyltransferase activity 4/1802 29/18639 0.137931034482759 1.42669065023537 0.306345863118525 0.767845342256131 GO:0035250 UDP-galactosyltransferase activity 4/1802 29/18639 0.137931034482759 1.42669065023537 0.306345863118525 0.767845342256131 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/1802 29/18639 0.137931034482759 1.42669065023537 0.306345863118525 0.767845342256131 GO:0106222 lncRNA binding 4/1802 29/18639 0.137931034482759 1.42669065023537 0.306345863118525 0.767845342256131 GO:0140034 methylation-dependent protein binding 9/1802 76/18639 0.118421052631579 1.22488901220866 0.312263221595209 0.776196499853495 GO:0051087 protein-folding chaperone binding 15/1802 134/18639 0.111940298507463 1.15785528517236 0.314212749044163 0.776196499853495 GO:0001221 transcription coregulator binding 13/1802 115/18639 0.11304347826087 1.16926603291029 0.318760804086308 0.776196499853495 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 8/1802 67/18639 0.119402985074627 1.23504563751719 0.319670946389164 0.776196499853495 GO:0061659 ubiquitin-like protein ligase activity 39/1802 372/18639 0.104838709677419 1.08439994987648 0.320084401256859 0.776196499853495 GO:0003995 acyl-CoA dehydrogenase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0004859 phospholipase inhibitor activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0005095 GTPase inhibitor activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0005165 neurotrophin receptor binding 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0005527 macrolide binding 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0015368 calcium:monoatomic cation antiporter activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0016423 tRNA (guanine) methyltransferase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0016801 hydrolase activity, acting on ether bonds 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0016803 ether hydrolase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0016840 carbon-nitrogen lyase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0034452 dynactin binding 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0035497 cAMP response element binding 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0036009 protein-glutamine N-methyltransferase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0070008 serine-type exopeptidase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:1990817 poly(A) RNA polymerase activity 2/1802 12/18639 0.166666666666667 1.72391786903441 0.325695521864579 0.776196499853495 GO:0031210 phosphatidylcholine binding 4/1802 30/18639 0.133333333333333 1.37913429522752 0.329060126320465 0.776261515031846 GO:0043995 histone H4K5 acetyltransferase activity 4/1802 30/18639 0.133333333333333 1.37913429522752 0.329060126320465 0.776261515031846 GO:0043996 histone H4K8 acetyltransferase activity 4/1802 30/18639 0.133333333333333 1.37913429522752 0.329060126320465 0.776261515031846 GO:0043997 histone H4K12 acetyltransferase activity 4/1802 30/18639 0.133333333333333 1.37913429522752 0.329060126320465 0.776261515031846 GO:0051721 protein phosphatase 2A binding 4/1802 30/18639 0.133333333333333 1.37913429522752 0.329060126320465 0.776261515031846 GO:0005123 death receptor binding 3/1802 21/18639 0.142857142857143 1.47764388774378 0.331700042377919 0.780905160497003 GO:1990782 protein tyrosine kinase binding 13/1802 117/18639 0.111111111111111 1.14927857935627 0.341402348094581 0.796647909563549 GO:0042826 histone deacetylase binding 14/1802 127/18639 0.110236220472441 1.14022914172354 0.343681192449431 0.796647909563549 GO:0008080 N-acetyltransferase activity 8/1802 69/18639 0.115942028985507 1.19924721324133 0.34957736100387 0.796647909563549 GO:0016279 protein-lysine N-methyltransferase activity 8/1802 69/18639 0.115942028985507 1.19924721324133 0.34957736100387 0.796647909563549 GO:0072349 modified amino acid transmembrane transporter activity 4/1802 31/18639 0.129032258064516 1.33464609215567 0.351859696342605 0.796647909563549 GO:0016758 hexosyltransferase activity 21/1802 197/18639 0.106598984771574 1.10260736801185 0.351889685577621 0.796647909563549 GO:0032813 tumor necrosis factor receptor superfamily binding 6/1802 50/18639 0.12 1.24122086570477 0.353193603735802 0.796647909563549 GO:0016757 glycosyltransferase activity 28/1802 267/18639 0.104868913857678 1.08471236703288 0.353628378590487 0.796647909563549 GO:0015377 chloride:monoatomic cation symporter activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0032931 histone H3K56 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0043992 histone H3K9 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0043993 histone H3K18 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0043994 histone H3K23 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0043999 histone H2AK5 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0044012 histone H2AK9 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0044014 histone H2BK5 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0044015 histone H2BK12 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0044016 histone H3K4 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0044017 histone H3K27 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0044018 histone H3K36 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0061133 endopeptidase activator activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0140517 protein-RNA adaptor activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0140908 histone H3K122 acetyltransferase activity 3/1802 22/18639 0.136363636363636 1.4104782564827 0.35920838879302 0.796647909563549 GO:0005035 death receptor activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0008253 5'-nucleotidase activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0009982 pseudouridine synthase activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0019104 DNA N-glycosylase activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0019855 calcium channel inhibitor activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0030955 potassium ion binding 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0035673 oligopeptide transmembrane transporter activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0043560 insulin receptor substrate binding 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0051011 microtubule minus-end binding 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0097157 pre-mRNA intronic binding 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1802 13/18639 0.153846153846154 1.59130880218561 0.362361774857367 0.796647909563549 GO:0017080 sodium channel regulator activity 5/1802 41/18639 0.121951219512195 1.26140331880566 0.3635303839315 0.797188567414165 GO:0016278 lysine N-methyltransferase activity 8/1802 70/18639 0.114285714285714 1.18211511019502 0.364664073830039 0.797188567414165 GO:0097110 scaffold protein binding 8/1802 70/18639 0.114285714285714 1.18211511019502 0.364664073830039 0.797188567414165 GO:0048306 calcium-dependent protein binding 9/1802 80/18639 0.1125 1.16364456159822 0.368259232186169 0.803537499122916 GO:0030544 Hsp70 protein binding 6/1802 51/18639 0.117647058823529 1.21688320167135 0.37103902603797 0.808086867569586 GO:0008378 galactosyltransferase activity 4/1802 32/18639 0.125 1.2929384017758 0.374663029652083 0.812934894562262 GO:0051059 NF-kappaB binding 4/1802 32/18639 0.125 1.2929384017758 0.374663029652083 0.812934894562262 GO:0005085 guanyl-nucleotide exchange factor activity 24/1802 230/18639 0.104347826086957 1.07932249191719 0.378020136847488 0.818691655779569 GO:0004402 histone acetyltransferase activity 5/1802 42/18639 0.119047619047619 1.23136990645315 0.383426699538294 0.82731957618374 GO:0019894 kinesin binding 5/1802 42/18639 0.119047619047619 1.23136990645315 0.383426699538294 0.82731957618374 GO:0072341 modified amino acid binding 10/1802 91/18639 0.10989010989011 1.13664914441829 0.384366041846869 0.827810567903534 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/1802 23/18639 0.130434782608696 1.34915311489649 0.386543561324045 0.827900850496988 GO:0044013 histone H2B acetyltransferase activity 3/1802 23/18639 0.130434782608696 1.34915311489649 0.386543561324045 0.827900850496988 GO:0140103 catalytic activity, acting on a glycoprotein 3/1802 23/18639 0.130434782608696 1.34915311489649 0.386543561324045 0.827900850496988 GO:0031072 heat shock protein binding 14/1802 131/18639 0.106870229007634 1.10541298472435 0.387988450470212 0.82946795569275 GO:0030159 signaling receptor complex adaptor activity 6/1802 52/18639 0.115384615384615 1.1934816016392 0.38891249851694 0.829917863807709 GO:0004065 arylsulfatase activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0004705 JUN kinase activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0005347 ATP transmembrane transporter activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0008195 phosphatidate phosphatase activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0008494 translation activator activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0015926 glucosidase activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0032454 histone H3K9 demethylase activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0034236 protein kinase A catalytic subunit binding 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0044548 S100 protein binding 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0061665 SUMO ligase activity 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0071933 Arp2/3 complex binding 2/1802 14/18639 0.142857142857143 1.47764388774378 0.398244872172661 0.83152385338744 GO:0004175 endopeptidase activity 41/1802 405/18639 0.101234567901235 1.04712048341349 0.401564512542126 0.83695255929479 GO:0008375 acetylglucosaminyltransferase activity 5/1802 43/18639 0.116279069767442 1.20273339700075 0.403292439473927 0.839050281052195 GO:0016860 intramolecular oxidoreductase activity 6/1802 53/18639 0.113207547169811 1.17096308085356 0.406776620858806 0.84354476780345 GO:0004857 enzyme inhibitor activity 42/1802 416/18639 0.100961538461538 1.0442964014343 0.40690336606856 0.84354476780345 GO:0030165 PDZ domain binding 9/1802 83/18639 0.108433734939759 1.12158511961275 0.410886090309675 0.850285628167531 GO:0035035 histone acetyltransferase binding 3/1802 24/18639 0.125 1.2929384017758 0.413588905621955 0.85284378942967 GO:0070300 phosphatidic acid binding 3/1802 24/18639 0.125 1.2929384017758 0.413588905621955 0.85284378942967 GO:0015035 protein-disulfide reductase activity 4/1802 34/18639 0.117647058823529 1.21688320167135 0.419981563649761 0.864493023937473 GO:0019205 nucleobase-containing compound kinase activity 5/1802 44/18639 0.113636363636364 1.17539854706891 0.423079099277641 0.867797164832269 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1802 44/18639 0.113636363636364 1.17539854706891 0.423079099277641 0.867797164832269 GO:0003925 G protein activity 6/1802 54/18639 0.111111111111111 1.14927857935627 0.424595528625804 0.869374295408117 GO:0048029 monosaccharide binding 8/1802 74/18639 0.108108108108108 1.11821699613043 0.425345281017184 0.86937884327414 GO:0000774 adenyl-nucleotide exchange factor activity 2/1802 15/18639 0.133333333333333 1.37913429522752 0.433153549808666 0.877626443253448 GO:0004129 cytochrome-c oxidase activity 2/1802 15/18639 0.133333333333333 1.37913429522752 0.433153549808666 0.877626443253448 GO:0008242 omega peptidase activity 2/1802 15/18639 0.133333333333333 1.37913429522752 0.433153549808666 0.877626443253448 GO:0047372 monoacylglycerol lipase activity 2/1802 15/18639 0.133333333333333 1.37913429522752 0.433153549808666 0.877626443253448 GO:0140776 protein-containing complex destabilizing activity 2/1802 15/18639 0.133333333333333 1.37913429522752 0.433153549808666 0.877626443253448 GO:0003707 nuclear steroid receptor activity 3/1802 25/18639 0.12 1.24122086570477 0.440241576325268 0.883249258640069 GO:0004709 MAP kinase kinase kinase activity 3/1802 25/18639 0.12 1.24122086570477 0.440241576325268 0.883249258640069 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/1802 25/18639 0.12 1.24122086570477 0.440241576325268 0.883249258640069 GO:0019707 protein-cysteine S-acyltransferase activity 3/1802 25/18639 0.12 1.24122086570477 0.440241576325268 0.883249258640069 GO:0047617 fatty acyl-CoA hydrolase activity 3/1802 25/18639 0.12 1.24122086570477 0.440241576325268 0.883249258640069 GO:0003725 double-stranded RNA binding 8/1802 75/18639 0.106666666666667 1.10330743618202 0.440485442829957 0.883249258640069 GO:0016874 ligase activity 17/1802 167/18639 0.101796407185629 1.05293187210485 0.449149557060952 0.899072177042835 GO:0004190 aspartic-type endopeptidase activity 4/1802 36/18639 0.111111111111111 1.14927857935627 0.464472873248115 0.908113974488717 GO:0016409 palmitoyltransferase activity 4/1802 36/18639 0.111111111111111 1.14927857935627 0.464472873248115 0.908113974488717 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1802 36/18639 0.111111111111111 1.14927857935627 0.464472873248115 0.908113974488717 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1802 26/18639 0.115384615384615 1.1934816016392 0.46641195870904 0.908113974488717 GO:0016289 acyl-CoA hydrolase activity 3/1802 26/18639 0.115384615384615 1.1934816016392 0.46641195870904 0.908113974488717 GO:0051139 metal cation:proton antiporter activity 3/1802 26/18639 0.115384615384615 1.1934816016392 0.46641195870904 0.908113974488717 GO:0097602 cullin family protein binding 3/1802 26/18639 0.115384615384615 1.1934816016392 0.46641195870904 0.908113974488717 GO:0008296 3'-5'-DNA exonuclease activity 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0017070 U6 snRNA binding 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0030275 LRR domain binding 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0097027 ubiquitin-protein transferase activator activity 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0140327 flippase activity 2/1802 16/18639 0.125 1.2929384017758 0.466940805455076 0.908113974488717 GO:0140767 enzyme-substrate adaptor activity 14/1802 139/18639 0.100719424460432 1.0417920935172 0.477584382305093 0.927263166311893 GO:0005504 fatty acid binding 5/1802 47/18639 0.106382978723404 1.1003731078943 0.481523277383147 0.931799619961065 GO:0061733 protein-lysine-acetyltransferase activity 5/1802 47/18639 0.106382978723404 1.1003731078943 0.481523277383147 0.931799619961065 GO:0043394 proteoglycan binding 4/1802 37/18639 0.108108108108108 1.11821699613043 0.486263487772985 0.937851469784381 GO:0070001 aspartic-type peptidase activity 4/1802 37/18639 0.108108108108108 1.11821699613043 0.486263487772985 0.937851469784381 GO:0032934 sterol binding 7/1802 68/18639 0.102941176470588 1.06477280146243 0.489821484739543 0.942706296274601 GO:0001671 ATPase activator activity 3/1802 27/18639 0.111111111111111 1.14927857935627 0.492022976645471 0.942706296274601 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1802 27/18639 0.111111111111111 1.14927857935627 0.492022976645471 0.942706296274601 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1802 27/18639 0.111111111111111 1.14927857935627 0.492022976645471 0.942706296274601 GO:0017116 single-stranded DNA helicase activity 6/1802 58/18639 0.103448275862069 1.07001798767653 0.494761642900644 0.943044104925488 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:0008429 phosphatidylethanolamine binding 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:0016018 cyclosporin A binding 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:0030169 low-density lipoprotein particle binding 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:0051787 misfolded protein binding 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:1990226 histone methyltransferase binding 2/1802 17/18639 0.117647058823529 1.21688320167135 0.499497135540929 0.943044104925488 GO:0042887 amide transmembrane transporter activity 4/1802 38/18639 0.105263157894737 1.08879023307436 0.50768476284083 0.956948750703217 GO:0015291 secondary active transmembrane transporter activity 28/1802 287/18639 0.0975609756097561 1.00912265504453 0.509317411284062 0.958472733532951 GO:0015459 potassium channel regulator activity 6/1802 59/18639 0.101694915254237 1.05188208958032 0.511877523492471 0.961734345430926 GO:0016866 intramolecular transferase activity 3/1802 28/18639 0.107142857142857 1.10823291580783 0.517009323525465 0.965139395281085 GO:0036408 histone H3K14 acetyltransferase activity 3/1802 28/18639 0.107142857142857 1.10823291580783 0.517009323525465 0.965139395281085 GO:0051119 sugar transmembrane transporter activity 3/1802 28/18639 0.107142857142857 1.10823291580783 0.517009323525465 0.965139395281085 GO:0141052 histone H3 demethylase activity 3/1802 28/18639 0.107142857142857 1.10823291580783 0.517009323525465 0.965139395281085 GO:0001222 transcription corepressor binding 5/1802 49/18639 0.102040816326531 1.05545991981698 0.519334783289228 0.965592218702071 GO:0060590 ATPase regulator activity 5/1802 49/18639 0.102040816326531 1.05545991981698 0.519334783289228 0.965592218702071 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 12/1802 122/18639 0.0983606557377049 1.01739415221703 0.519742673179275 0.965592218702071 GO:0000217 DNA secondary structure binding 4/1802 39/18639 0.102564102564103 1.0608725347904 0.528694054244011 0.969004781100808 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/1802 39/18639 0.102564102564103 1.0608725347904 0.528694054244011 0.969004781100808 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0004706 JUN kinase kinase kinase activity 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0008308 voltage-gated monoatomic anion channel activity 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0008525 phosphatidylcholine transporter activity 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0015172 acidic amino acid transmembrane transporter activity 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0070064 proline-rich region binding 2/1802 18/18639 0.111111111111111 1.14927857935627 0.530744665142919 0.969004781100808 GO:0061630 ubiquitin protein ligase activity 34/1802 353/18639 0.0963172804532578 0.996258485221017 0.536150100508463 0.977339446538154 GO:0010484 histone H3 acetyltransferase activity 3/1802 29/18639 0.103448275862069 1.07001798767653 0.541316645880112 0.985213238119828 GO:0004722 protein serine/threonine phosphatase activity 10/1802 103/18639 0.0970873786407767 1.00422400137927 0.543271159630397 0.987225560390863 GO:0015036 disulfide oxidoreductase activity 4/1802 40/18639 0.1 1.03435072142064 0.549253980247734 0.991898104080924 GO:0032451 demethylase activity 4/1802 40/18639 0.1 1.03435072142064 0.549253980247734 0.991898104080924 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/1802 40/18639 0.1 1.03435072142064 0.549253980247734 0.991898104080924 GO:0140662 ATP-dependent protein folding chaperone 4/1802 40/18639 0.1 1.03435072142064 0.549253980247734 0.991898104080924 GO:0002020 protease binding 13/1802 136/18639 0.0955882352941176 0.988717601357968 0.559944965365168 0.996964965573248 GO:0008301 DNA binding, bending 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0030506 ankyrin binding 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0042577 lipid phosphatase activity 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0042800 histone H3K4 methyltransferase activity 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0043395 heparan sulfate proteoglycan binding 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0046527 glucosyltransferase activity 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0046624 sphingolipid transporter activity 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0097001 ceramide binding 2/1802 19/18639 0.105263157894737 1.08879023307436 0.560632061465954 0.996964965573248 GO:0005201 extracellular matrix structural constituent 16/1802 168/18639 0.0952380952380952 0.985095925162518 0.563833660012045 0.998449115953225 GO:0031624 ubiquitin conjugating enzyme binding 3/1802 30/18639 0.1 1.03435072142064 0.564900703608961 0.998449115953225 GO:0032452 histone demethylase activity 3/1802 30/18639 0.1 1.03435072142064 0.564900703608961 0.998449115953225 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/1802 30/18639 0.1 1.03435072142064 0.564900703608961 0.998449115953225 GO:0001530 lipopolysaccharide binding 4/1802 41/18639 0.0975609756097561 1.00912265504453 0.569332206876517 0.999782097928543 GO:0042169 SH2 domain binding 4/1802 41/18639 0.0975609756097561 1.00912265504453 0.569332206876517 0.999782097928543 GO:0140828 metal cation:monoatomic cation antiporter activity 4/1802 41/18639 0.0975609756097561 1.00912265504453 0.569332206876517 0.999782097928543 GO:0051117 ATPase binding 8/1802 84/18639 0.0952380952380952 0.985095925162518 0.572025693769915 0.999782097928543 GO:0005507 copper ion binding 6/1802 63/18639 0.0952380952380952 0.985095925162518 0.577893325298616 0.999782097928543 GO:1901682 sulfur compound transmembrane transporter activity 6/1802 63/18639 0.0952380952380952 0.985095925162518 0.577893325298616 0.999782097928543 GO:0005164 tumor necrosis factor receptor binding 3/1802 31/18639 0.0967741935483871 1.00098456911675 0.587726525816071 0.999782097928543 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/1802 31/18639 0.0967741935483871 1.00098456911675 0.587726525816071 0.999782097928543 GO:0016878 acid-thiol ligase activity 3/1802 31/18639 0.0967741935483871 1.00098456911675 0.587726525816071 0.999782097928543 GO:0017147 Wnt-protein binding 3/1802 31/18639 0.0967741935483871 1.00098456911675 0.587726525816071 0.999782097928543 GO:0047499 calcium-independent phospholipase A2 activity 3/1802 31/18639 0.0967741935483871 1.00098456911675 0.587726525816071 0.999782097928543 GO:0140457 protein demethylase activity 3/1802 31/18639 0.0967741935483871 1.00098456911675 0.587726525816071 0.999782097928543 GO:0004520 DNA endonuclease activity 4/1802 42/18639 0.0952380952380952 0.985095925162518 0.588901207648961 0.999782097928543 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/1802 20/18639 0.1 1.03435072142064 0.589130134377147 0.999782097928543 GO:0016505 peptidase activator activity involved in apoptotic process 2/1802 20/18639 0.1 1.03435072142064 0.589130134377147 0.999782097928543 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1802 20/18639 0.1 1.03435072142064 0.589130134377147 0.999782097928543 GO:0042288 MHC class I protein binding 2/1802 20/18639 0.1 1.03435072142064 0.589130134377147 0.999782097928543 GO:0140664 ATP-dependent DNA damage sensor activity 2/1802 20/18639 0.1 1.03435072142064 0.589130134377147 0.999782097928543 GO:0140939 histone H4 methyltransferase activity 2/1802 20/18639 0.1 1.03435072142064 0.589130134377147 0.999782097928543 GO:0008146 sulfotransferase activity 5/1802 53/18639 0.0943396226415094 0.975802567377966 0.591073905086642 0.999782097928543 GO:0034212 protein N-acetyltransferase activity 5/1802 53/18639 0.0943396226415094 0.975802567377966 0.591073905086642 0.999782097928543 GO:0019842 vitamin binding 14/1802 150/18639 0.0933333333333333 0.965394006659268 0.596091527891964 0.999782097928543 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/1802 86/18639 0.0930232558139535 0.962186717600599 0.599386141392731 0.999782097928543 GO:0050660 flavin adenine dinucleotide binding 8/1802 86/18639 0.0930232558139535 0.962186717600599 0.599386141392731 0.999782097928543 GO:0004843 cysteine-type deubiquitinase activity 10/1802 108/18639 0.0925925925925926 0.957732149463559 0.605196717953821 0.999782097928543 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 5/1802 54/18639 0.0925925925925926 0.957732149463559 0.608061494521421 0.999782097928543 GO:0050661 NADP binding 5/1802 54/18639 0.0925925925925926 0.957732149463559 0.608061494521421 0.999782097928543 GO:0043425 bHLH transcription factor binding 3/1802 32/18639 0.09375 0.969703801331854 0.60976757714338 0.999782097928543 GO:0071813 lipoprotein particle binding 3/1802 32/18639 0.09375 0.969703801331854 0.60976757714338 0.999782097928543 GO:0071814 protein-lipid complex binding 3/1802 32/18639 0.09375 0.969703801331854 0.60976757714338 0.999782097928543 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 12/1802 130/18639 0.0923076923076923 0.954785281311364 0.61089105381468 0.999782097928543 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/1802 21/18639 0.0952380952380952 0.985095925162518 0.616228038798119 0.999782097928543 GO:0001846 opsonin binding 2/1802 21/18639 0.0952380952380952 0.985095925162518 0.616228038798119 0.999782097928543 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1802 21/18639 0.0952380952380952 0.985095925162518 0.616228038798119 0.999782097928543 GO:0036122 BMP binding 2/1802 21/18639 0.0952380952380952 0.985095925162518 0.616228038798119 0.999782097928543 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1802 21/18639 0.0952380952380952 0.985095925162518 0.616228038798119 0.999782097928543 GO:0061891 calcium ion sensor activity 2/1802 21/18639 0.0952380952380952 0.985095925162518 0.616228038798119 0.999782097928543 GO:0070182 DNA polymerase binding 2/1802 21/18639 0.0952380952380952 0.985095925162518 0.616228038798119 0.999782097928543 GO:0140313 molecular sequestering activity 5/1802 55/18639 0.0909090909090909 0.940318837655131 0.624634142546471 0.999782097928543 GO:0001223 transcription coactivator binding 4/1802 44/18639 0.0909090909090909 0.940318837655131 0.626423894895584 0.999782097928543 GO:0016790 thiolester hydrolase activity 4/1802 44/18639 0.0909090909090909 0.940318837655131 0.626423894895584 0.999782097928543 GO:0030296 protein tyrosine kinase activator activity 3/1802 33/18639 0.0909090909090909 0.940318837655131 0.631004946059561 0.999782097928543 GO:0071889 14-3-3 protein binding 3/1802 33/18639 0.0909090909090909 0.940318837655131 0.631004946059561 0.999782097928543 GO:0140416 transcription regulator inhibitor activity 3/1802 33/18639 0.0909090909090909 0.940318837655131 0.631004946059561 0.999782097928543 GO:0000182 rDNA binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0005337 nucleoside transmembrane transporter activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0005345 purine nucleobase transmembrane transporter activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0008190 eukaryotic initiation factor 4E binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0015279 store-operated calcium channel activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0016868 intramolecular phosphotransferase activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0031996 thioesterase binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0032356 oxidized DNA binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0035256 G protein-coupled glutamate receptor binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0035374 chondroitin sulfate binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0043121 neurotrophin binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0043295 glutathione binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0050308 sugar-phosphatase activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0050815 phosphoserine residue binding 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0051864 histone H3K36 demethylase activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1802 10/18639 0.1 1.03435072142064 0.638333088898808 0.999782097928543 GO:0030170 pyridoxal phosphate binding 5/1802 56/18639 0.0892857142857143 0.923527429839861 0.640778408889655 0.999782097928543 GO:0008970 phospholipase A1 activity 2/1802 22/18639 0.0909090909090909 0.940318837655131 0.641930003798628 0.999782097928543 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1802 22/18639 0.0909090909090909 0.940318837655131 0.641930003798628 0.999782097928543 GO:0140784 metal ion sensor activity 2/1802 22/18639 0.0909090909090909 0.940318837655131 0.641930003798628 0.999782097928543 GO:0016791 phosphatase activity 25/1802 273/18639 0.0915750915750916 0.947207620348575 0.643332510265152 0.999782097928543 GO:0051427 hormone receptor binding 3/1802 34/18639 0.0882352941176471 0.912662401253509 0.651426563712122 0.999782097928543 GO:0070279 vitamin B6 binding 5/1802 57/18639 0.087719298245614 0.907325194228635 0.656483280454294 0.999782097928543 GO:0022804 active transmembrane transporter activity 42/1802 457/18639 0.0919037199124726 0.950606789927069 0.660176128502922 0.999782097928543 GO:0003887 DNA-directed DNA polymerase activity 2/1802 23/18639 0.0869565217391304 0.899435409930994 0.666252522129541 0.999782097928543 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1802 23/18639 0.0869565217391304 0.899435409930994 0.666252522129541 0.999782097928543 GO:0004602 glutathione peroxidase activity 2/1802 23/18639 0.0869565217391304 0.899435409930994 0.666252522129541 0.999782097928543 GO:0099186 structural constituent of postsynapse 2/1802 23/18639 0.0869565217391304 0.899435409930994 0.666252522129541 0.999782097928543 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1802 23/18639 0.0869565217391304 0.899435409930994 0.666252522129541 0.999782097928543 GO:0004623 phospholipase A2 activity 3/1802 35/18639 0.0857142857142857 0.886586332646266 0.671026459595527 0.999782097928543 GO:0005154 epidermal growth factor receptor binding 3/1802 35/18639 0.0857142857142857 0.886586332646266 0.671026459595527 0.999782097928543 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0004016 adenylate cyclase activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0005536 D-glucose binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0008199 ferric iron binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0008432 JUN kinase binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0008526 phosphatidylinositol transfer activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0015205 nucleobase transmembrane transporter activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0015217 ADP transmembrane transporter activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0019107 myristoyltransferase activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0019203 carbohydrate phosphatase activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0019864 IgG binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0032794 GTPase activating protein binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0034056 estrogen response element binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0034511 U3 snoRNA binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0050998 nitric-oxide synthase binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0140031 phosphorylation-dependent protein binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0140537 transcription regulator activator activity 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:1900750 oligopeptide binding 1/1802 11/18639 0.0909090909090909 0.940318837655131 0.673317455950413 0.999782097928543 GO:0033192 calmodulin-dependent protein phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:0140791 histone H2AXS140 phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/1802 81/18639 0.0864197530864197 0.893883339499322 0.677959607025491 0.999782097928543 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1802 70/18639 0.0857142857142857 0.886586332646266 0.681350165104317 0.999782097928543 GO:0017124 SH3 domain binding 10/1802 115/18639 0.0869565217391304 0.899435409930994 0.684368791790671 0.999782097928543 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 24/1802 268/18639 0.0895522388059701 0.92628422813789 0.684742229486696 0.999782097928543 GO:0036002 pre-mRNA binding 5/1802 59/18639 0.0847457627118644 0.876568407983596 0.686542123456813 0.999782097928543 GO:0004622 lysophospholipase activity 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0015149 hexose transmembrane transporter activity 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0015295 solute:proton symporter activity 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0030552 cAMP binding 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0050431 transforming growth factor beta binding 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0055056 D-glucose transmembrane transporter activity 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0070840 dynein complex binding 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0140033 acetylation-dependent protein binding 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0140612 DNA damage sensor activity 2/1802 24/18639 0.0833333333333333 0.861958934517203 0.689221941812049 0.999782097928543 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 7/1802 82/18639 0.0853658536585366 0.882982323163964 0.690476408063802 0.999782097928543 GO:0033549 MAP kinase phosphatase activity 7/1802 82/18639 0.0853658536585366 0.882982323163964 0.690476408063802 0.999782097928543 GO:0140299 molecular sensor activity 6/1802 71/18639 0.0845070422535211 0.874099201200544 0.694693324898032 0.999782097928543 GO:0008236 serine-type peptidase activity 17/1802 194/18639 0.0876288659793814 0.906389807430461 0.701224063242788 0.999782097928543 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/1802 83/18639 0.0843373493975904 0.872343981921025 0.702675055444945 0.999782097928543 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0004000 adenosine deaminase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0004032 aldose reductase (NADPH) activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0004126 cytidine deaminase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0005025 transforming growth factor beta receptor activity, type I 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0005026 transforming growth factor beta receptor activity, type II 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0005247 voltage-gated chloride channel activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0015166 polyol transmembrane transporter activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0016273 arginine N-methyltransferase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0016274 protein-arginine N-methyltransferase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0016361 activin receptor activity, type I 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0016362 activin receptor activity, type II 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0017002 activin receptor activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0035251 UDP-glucosyltransferase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0042301 phosphate ion binding 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0043047 single-stranded telomeric DNA binding 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0070410 co-SMAD binding 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0097371 MDM2/MDM4 family protein binding 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0097677 STAT family protein binding 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1802 12/18639 0.0833333333333333 0.861958934517203 0.704919449958216 0.999782097928543 GO:0008013 beta-catenin binding 9/1802 106/18639 0.0849056603773585 0.878222310640169 0.707355847046938 0.999999999981986 GO:0046982 protein heterodimerization activity 33/1802 369/18639 0.0894308943089431 0.925029100457486 0.708476937044776 0.999999999981986 GO:0017018 myosin phosphatase activity 7/1802 84/18639 0.0833333333333333 0.861958934517203 0.714552270142675 0.999999999981986 GO:0022853 active monoatomic ion transmembrane transporter activity 10/1802 118/18639 0.0847457627118644 0.876568407983596 0.715176807851041 0.999999999981986 GO:0000146 microfilament motor activity 3/1802 38/18639 0.0789473684210526 0.816592674805771 0.724913128260822 0.999999999981986 GO:0003774 cytoskeletal motor activity 13/1802 153/18639 0.0849673202614379 0.878860090095972 0.728089232266143 0.999999999981986 GO:0015179 L-amino acid transmembrane transporter activity 5/1802 62/18639 0.0806451612903226 0.834153807597293 0.728184201861245 0.999999999981986 GO:0004435 phosphatidylinositol phospholipase C activity 2/1802 26/18639 0.0769230769230769 0.795654401092803 0.73124411251504 0.999999999981986 GO:0015145 monosaccharide transmembrane transporter activity 2/1802 26/18639 0.0769230769230769 0.795654401092803 0.73124411251504 0.999999999981986 GO:0019865 immunoglobulin binding 2/1802 26/18639 0.0769230769230769 0.795654401092803 0.73124411251504 0.999999999981986 GO:0030507 spectrin binding 2/1802 26/18639 0.0769230769230769 0.795654401092803 0.73124411251504 0.999999999981986 GO:0120014 phospholipid transfer activity 2/1802 26/18639 0.0769230769230769 0.795654401092803 0.73124411251504 0.999999999981986 GO:0017171 serine hydrolase activity 17/1802 198/18639 0.0858585858585859 0.888078902229846 0.732246607729007 0.999999999981986 GO:0002161 aminoacyl-tRNA editing activity 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0005542 folic acid binding 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0017154 semaphorin receptor activity 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0032396 inhibitory MHC class I receptor activity 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0046974 histone H3K9 methyltransferase activity 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0061459 L-arginine transmembrane transporter activity 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0070123 transforming growth factor beta receptor activity, type III 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0089720 caspase binding 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0140333 glycerophospholipid flippase activity 1/1802 13/18639 0.0769230769230769 0.795654401092803 0.733465922883287 0.999999999981986 GO:0004620 phospholipase activity 9/1802 109/18639 0.0825688073394495 0.854051054384018 0.738076755309178 0.999999999981986 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1802 39/18639 0.0769230769230769 0.795654401092803 0.741264717762222 0.999999999981986 GO:0015399 primary active transmembrane transporter activity 14/1802 166/18639 0.0843373493975904 0.872343981921025 0.74308634432105 0.999999999981986 GO:0004222 metalloendopeptidase activity 9/1802 110/18639 0.0818181818181818 0.846286953889618 0.747814790374151 0.999999999981986 GO:0004364 glutathione transferase activity 2/1802 27/18639 0.0740740740740741 0.766185719570847 0.750381803384605 0.999999999981986 GO:0005104 fibroblast growth factor receptor binding 2/1802 27/18639 0.0740740740740741 0.766185719570847 0.750381803384605 0.999999999981986 GO:0015252 proton channel activity 2/1802 27/18639 0.0740740740740741 0.766185719570847 0.750381803384605 0.999999999981986 GO:0001217 DNA-binding transcription repressor activity 24/1802 278/18639 0.0863309352517986 0.892964651586167 0.750595842051215 0.999999999981986 GO:0005080 protein kinase C binding 4/1802 52/18639 0.0769230769230769 0.795654401092803 0.753422379539447 0.999999999981986 GO:0015144 carbohydrate transmembrane transporter activity 3/1802 40/18639 0.075 0.775763041065483 0.756833155939073 0.999999999981986 GO:0071949 FAD binding 3/1802 40/18639 0.075 0.775763041065483 0.756833155939073 0.999999999981986 GO:0005161 platelet-derived growth factor receptor binding 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0005313 L-glutamate transmembrane transporter activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0005545 1-phosphatidylinositol binding 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0008331 high voltage-gated calcium channel activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0015386 potassium:proton antiporter activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0019763 immunoglobulin receptor activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0031404 chloride ion binding 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0042813 Wnt receptor activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0043176 amine binding 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0070742 C2H2 zinc finger domain binding 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0098599 palmitoyl hydrolase activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0098821 BMP receptor activity 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0098847 sequence-specific single stranded DNA binding 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:1990825 sequence-specific mRNA binding 1/1802 14/18639 0.0714285714285714 0.738821943871888 0.759252157553335 0.999999999981986 GO:0120013 lipid transfer activity 5/1802 65/18639 0.0769230769230769 0.795654401092803 0.76567622572816 0.999999999981986 GO:0005544 calcium-dependent phospholipid binding 4/1802 53/18639 0.0754716981132075 0.780642053902373 0.766675316229472 0.999999999981986 GO:0046625 sphingolipid binding 2/1802 28/18639 0.0714285714285714 0.738821943871888 0.768333532604539 0.999999999981986 GO:0051959 dynein light intermediate chain binding 2/1802 28/18639 0.0714285714285714 0.738821943871888 0.768333532604539 0.999999999981986 GO:0004812 aminoacyl-tRNA ligase activity 3/1802 41/18639 0.0731707317073171 0.756841991283398 0.771635862444012 0.999999999981986 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/1802 41/18639 0.0731707317073171 0.756841991283398 0.771635862444012 0.999999999981986 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/1802 41/18639 0.0731707317073171 0.756841991283398 0.771635862444012 0.999999999981986 GO:0061134 peptidase regulator activity 19/1802 226/18639 0.084070796460177 0.869586889689922 0.772141891684844 0.999999999981986 GO:0044325 transmembrane transporter binding 11/1802 136/18639 0.0808823529411765 0.83660720114905 0.775055488807862 0.999999999981986 GO:0042277 peptide binding 21/1802 249/18639 0.0843373493975904 0.872343981921025 0.776370171723572 0.999999999981986 GO:0015485 cholesterol binding 4/1802 54/18639 0.0740740740740741 0.766185719570847 0.779364421966116 0.999999999981986 GO:0004089 carbonate dehydratase activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0005041 low-density lipoprotein particle receptor activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0005523 tropomyosin binding 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0010181 FMN binding 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0031386 protein tag activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0033130 acetylcholine receptor binding 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0034483 heparan sulfate sulfotransferase activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0050700 CARD domain binding 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0051371 muscle alpha-actinin binding 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0120283 protein serine/threonine kinase binding 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0140161 monocarboxylate:sodium symporter activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0141047 molecular tag activity 1/1802 15/18639 0.0666666666666667 0.689567147613762 0.782544915249383 0.999999999981986 GO:0004629 phospholipase C activity 2/1802 29/18639 0.0689655172413793 0.713345325117685 0.78514959828783 0.999999999981986 GO:0043236 laminin binding 2/1802 29/18639 0.0689655172413793 0.713345325117685 0.78514959828783 0.999999999981986 GO:0008307 structural constituent of muscle 3/1802 42/18639 0.0714285714285714 0.738821943871888 0.785692374351323 0.999999999981986 GO:0033293 monocarboxylic acid binding 6/1802 79/18639 0.0759493670886076 0.785582826395426 0.787770880511223 0.999999999981986 GO:0005178 integrin binding 13/1802 161/18639 0.0807453416149068 0.835190023507352 0.790968623524602 0.999999999981986 GO:0008374 O-acyltransferase activity 4/1802 55/18639 0.0727272727272727 0.752255070124105 0.791500130155892 0.999999999981986 GO:0042578 phosphoric ester hydrolase activity 31/1802 363/18639 0.0853994490358127 0.883329817191183 0.792981057013366 0.999999999981986 GO:0005516 calmodulin binding 17/1802 207/18639 0.0821256038647343 0.849466776045939 0.794298382244708 0.999999999981986 GO:0098918 structural constituent of synapse 2/1802 30/18639 0.0666666666666667 0.689567147613762 0.800881662193464 0.999999999981986 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0005024 transforming growth factor beta receptor activity 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0005149 interleukin-1 receptor binding 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0005159 insulin-like growth factor receptor binding 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0015378 sodium:chloride symporter activity 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0015385 sodium:proton antiporter activity 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0070411 I-SMAD binding 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0140328 floppase activity 1/1802 16/18639 0.0625 0.646469200887902 0.80358518923567 0.999999999981986 GO:0051015 actin filament binding 17/1802 209/18639 0.0813397129186603 0.841337907375643 0.806607084067323 0.999999999981986 GO:0051219 phosphoprotein binding 7/1802 93/18639 0.0752688172043011 0.778543553757474 0.806877997690378 0.999999999981986 GO:0004721 phosphoprotein phosphatase activity 14/1802 175/18639 0.08 0.827480577136515 0.808280637022929 0.999999999981986 GO:0030547 signaling receptor inhibitor activity 3/1802 44/18639 0.0681818181818182 0.705239128241348 0.811653224577092 0.999999999981986 GO:0004252 serine-type endopeptidase activity 14/1802 176/18639 0.0795454545454545 0.822778982948239 0.814714066207946 0.999999999981986 GO:0016298 lipase activity 10/1802 130/18639 0.0769230769230769 0.795654401092803 0.818188908806597 0.999999999981986 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1802 70/18639 0.0714285714285714 0.738821943871888 0.819229482972706 0.999999999981986 GO:0005506 iron ion binding 12/1802 154/18639 0.0779220779220779 0.805987575132969 0.822244427770913 0.999999999981986 GO:0004550 nucleoside diphosphate kinase activity 1/1802 17/18639 0.0588235294117647 0.608441600835673 0.822590692591591 0.999999999981986 GO:0016805 dipeptidase activity 1/1802 17/18639 0.0588235294117647 0.608441600835673 0.822590692591591 0.999999999981986 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1802 17/18639 0.0588235294117647 0.608441600835673 0.822590692591591 0.999999999981986 GO:0032977 membrane insertase activity 1/1802 17/18639 0.0588235294117647 0.608441600835673 0.822590692591591 0.999999999981986 GO:0038191 neuropilin binding 1/1802 17/18639 0.0588235294117647 0.608441600835673 0.822590692591591 0.999999999981986 GO:0045236 CXCR chemokine receptor binding 1/1802 17/18639 0.0588235294117647 0.608441600835673 0.822590692591591 0.999999999981986 GO:0070402 NADPH binding 1/1802 17/18639 0.0588235294117647 0.608441600835673 0.822590692591591 0.999999999981986 GO:0008009 chemokine activity 3/1802 45/18639 0.0666666666666667 0.689567147613762 0.82360387114618 0.999999999981986 GO:0140303 intramembrane lipid transporter activity 3/1802 45/18639 0.0666666666666667 0.689567147613762 0.82360387114618 0.999999999981986 GO:0015106 bicarbonate transmembrane transporter activity 2/1802 32/18639 0.0625 0.646469200887902 0.829302979045254 0.999999999981986 GO:0042910 xenobiotic transmembrane transporter activity 2/1802 32/18639 0.0625 0.646469200887902 0.829302979045254 0.999999999981986 GO:0047498 calcium-dependent phospholipase A2 activity 2/1802 32/18639 0.0625 0.646469200887902 0.829302979045254 0.999999999981986 GO:0070717 poly-purine tract binding 2/1802 32/18639 0.0625 0.646469200887902 0.829302979045254 0.999999999981986 GO:0120015 sterol transfer activity 2/1802 32/18639 0.0625 0.646469200887902 0.829302979045254 0.999999999981986 GO:0005496 steroid binding 8/1802 108/18639 0.0740740740740741 0.766185719570847 0.831277458801696 0.999999999981986 GO:0045309 protein phosphorylated amino acid binding 4/1802 59/18639 0.0677966101694915 0.701254726386877 0.834757108854809 0.999999999981986 GO:0004180 carboxypeptidase activity 3/1802 46/18639 0.0652173913043478 0.674576557448246 0.834900338262044 0.999999999981986 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0015373 monoatomic anion:sodium symporter activity 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0016854 racemase and epimerase activity 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0030228 lipoprotein particle receptor activity 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0031690 adrenergic receptor binding 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0032393 MHC class I receptor activity 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0050811 GABA receptor binding 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0098641 cadherin binding involved in cell-cell adhesion 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:1901611 phosphatidylglycerol binding 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:1990381 ubiquitin-specific protease binding 1/1802 18/18639 0.0555555555555556 0.574639289678135 0.839758105970925 0.999999999981986 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1802 33/18639 0.0606060606060606 0.626879225103421 0.842096400528202 0.999999999981986 GO:0019239 deaminase activity 2/1802 33/18639 0.0606060606060606 0.626879225103421 0.842096400528202 0.999999999981986 GO:0001784 phosphotyrosine residue binding 3/1802 47/18639 0.0638297872340425 0.660223864736581 0.845567588353985 0.999999999981986 GO:0003779 actin binding 37/1802 443/18639 0.0835214446952596 0.863904665746362 0.848922617441705 0.999999999981986 GO:0016209 antioxidant activity 6/1802 86/18639 0.0697674418604651 0.721640038200449 0.849960156648388 0.999999999981986 GO:0015026 coreceptor activity 4/1802 61/18639 0.0655737704918033 0.678262768144684 0.8534108701084 0.999999999981986 GO:0015020 glucuronosyltransferase activity 2/1802 34/18639 0.0588235294117647 0.608441600835673 0.854013265329207 0.999999999981986 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1802 34/18639 0.0588235294117647 0.608441600835673 0.854013265329207 0.999999999981986 GO:0090482 vitamin transmembrane transporter activity 2/1802 34/18639 0.0588235294117647 0.608441600835673 0.854013265329207 0.999999999981986 GO:0008574 plus-end-directed microtubule motor activity 1/1802 19/18639 0.0526315789473684 0.544395116537181 0.855265108443424 0.999999999981986 GO:0015245 fatty acid transmembrane transporter activity 1/1802 19/18639 0.0526315789473684 0.544395116537181 0.855265108443424 0.999999999981986 GO:0022821 solute:potassium antiporter activity 1/1802 19/18639 0.0526315789473684 0.544395116537181 0.855265108443424 0.999999999981986 GO:1990380 K48-linked deubiquitinase activity 1/1802 19/18639 0.0526315789473684 0.544395116537181 0.855265108443424 0.999999999981986 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/1802 48/18639 0.0625 0.646469200887902 0.855630878595088 0.999999999981986 GO:0140789 histone phosphatase activity 10/1802 136/18639 0.0735294117647059 0.760552001044591 0.857812115774542 0.999999999981986 GO:0034061 DNA polymerase activity 2/1802 35/18639 0.0571428571428571 0.591057555097511 0.865103374767612 0.999999999981986 GO:0001614 purinergic nucleotide receptor activity 1/1802 20/18639 0.05 0.517175360710322 0.869272212341649 0.999999999981986 GO:0001972 retinoic acid binding 1/1802 20/18639 0.05 0.517175360710322 0.869272212341649 0.999999999981986 GO:0015095 magnesium ion transmembrane transporter activity 1/1802 20/18639 0.05 0.517175360710322 0.869272212341649 0.999999999981986 GO:0016502 nucleotide receptor activity 1/1802 20/18639 0.05 0.517175360710322 0.869272212341649 0.999999999981986 GO:0070851 growth factor receptor binding 10/1802 139/18639 0.0719424460431655 0.744137209655139 0.874882507129175 0.999999999981986 GO:0031406 carboxylic acid binding 14/1802 187/18639 0.0748663101604278 0.774380219245402 0.875268968954321 0.999999999981986 GO:0045505 dynein intermediate chain binding 2/1802 36/18639 0.0555555555555556 0.574639289678135 0.875415099262508 0.999999999981986 GO:0055106 ubiquitin-protein transferase regulator activity 2/1802 36/18639 0.0555555555555556 0.574639289678135 0.875415099262508 0.999999999981986 GO:0008514 organic anion transmembrane transporter activity 21/1802 269/18639 0.0780669144981413 0.807485693302361 0.875950876217554 0.999999999981986 GO:0046943 carboxylic acid transmembrane transporter activity 14/1802 188/18639 0.074468085106383 0.770261175526011 0.879891828674305 0.999999999981986 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1802 21/18639 0.0476190476190476 0.492547962581259 0.881924421018825 0.999999999981986 GO:0008373 sialyltransferase activity 1/1802 21/18639 0.0476190476190476 0.492547962581259 0.881924421018825 0.999999999981986 GO:0009975 cyclase activity 1/1802 21/18639 0.0476190476190476 0.492547962581259 0.881924421018825 0.999999999981986 GO:0015125 bile acid transmembrane transporter activity 1/1802 21/18639 0.0476190476190476 0.492547962581259 0.881924421018825 0.999999999981986 GO:0015174 basic amino acid transmembrane transporter activity 1/1802 21/18639 0.0476190476190476 0.492547962581259 0.881924421018825 0.999999999981986 GO:0051428 peptide hormone receptor binding 1/1802 21/18639 0.0476190476190476 0.492547962581259 0.881924421018825 0.999999999981986 GO:1904047 S-adenosyl-L-methionine binding 1/1802 21/18639 0.0476190476190476 0.492547962581259 0.881924421018825 0.999999999981986 GO:0015294 solute:monoatomic cation symporter activity 8/1802 116/18639 0.0689655172413793 0.713345325117685 0.883408813724385 0.999999999981986 GO:0005342 organic acid transmembrane transporter activity 14/1802 189/18639 0.0740740740740741 0.766185719570847 0.884376842654081 0.999999999981986 GO:0043177 organic acid binding 14/1802 189/18639 0.0740740740740741 0.766185719570847 0.884376842654081 0.999999999981986 GO:0022829 wide pore channel activity 2/1802 37/18639 0.0540540540540541 0.559108498065213 0.884995189479537 0.999999999981986 GO:0023023 MHC protein complex binding 2/1802 37/18639 0.0540540540540541 0.559108498065213 0.884995189479537 0.999999999981986 GO:0030551 cyclic nucleotide binding 2/1802 37/18639 0.0540540540540541 0.559108498065213 0.884995189479537 0.999999999981986 GO:0008093 cytoskeletal anchor activity 1/1802 22/18639 0.0454545454545455 0.470159418827565 0.893352726600739 0.999999999981986 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/1802 22/18639 0.0454545454545455 0.470159418827565 0.893352726600739 0.999999999981986 GO:0005501 retinoid binding 2/1802 38/18639 0.0526315789473684 0.544395116537181 0.893888637325021 0.999999999981986 GO:0019840 isoprenoid binding 2/1802 38/18639 0.0526315789473684 0.544395116537181 0.893888637325021 0.999999999981986 GO:0005126 cytokine receptor binding 21/1802 275/18639 0.0763636363636364 0.78986782363031 0.897888555501945 0.999999999981986 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 13/1802 181/18639 0.0718232044198895 0.742903833064551 0.901217370267125 0.999999999981986 GO:0042562 hormone binding 6/1802 94/18639 0.0638297872340425 0.660223864736581 0.901909435685571 0.999999999981986 GO:0005212 structural constituent of eye lens 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0005283 amino acid:sodium symporter activity 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0016849 phosphorus-oxygen lyase activity 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0031681 G-protein beta-subunit binding 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0043274 phospholipase binding 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0070577 lysine-acetylated histone binding 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0071617 lysophospholipid acyltransferase activity 1/1802 23/18639 0.0434782608695652 0.449717704965497 0.903675463167612 0.999999999981986 GO:0005548 phospholipid transporter activity 4/1802 68/18639 0.0588235294117647 0.608441600835673 0.90520127052343 0.999999999981986 GO:0015293 symporter activity 10/1802 146/18639 0.0684931506849315 0.708459398233318 0.908296315212165 0.999999999981986 GO:0051082 unfolded protein binding 8/1802 121/18639 0.0661157024793388 0.683868245567368 0.908641028405357 0.999999999981986 GO:0015085 calcium ion transmembrane transporter activity 10/1802 147/18639 0.0680272108843537 0.703639946544656 0.912396044284591 0.999999999981986 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0004806 triacylglycerol lipase activity 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0005315 phosphate transmembrane transporter activity 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0030215 semaphorin receptor binding 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0050699 WW domain binding 1/1802 24/18639 0.0416666666666667 0.430979467258602 0.912999529313506 0.999999999981986 GO:0042287 MHC protein binding 2/1802 41/18639 0.0487804878048781 0.504561327522265 0.916870867139668 0.999999999981986 GO:0001848 complement binding 1/1802 25/18639 0.04 0.413740288568258 0.921421492685897 0.999999999981986 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1802 25/18639 0.04 0.413740288568258 0.921421492685897 0.999999999981986 GO:0120020 cholesterol transfer activity 1/1802 25/18639 0.04 0.413740288568258 0.921421492685897 0.999999999981986 GO:0005200 structural constituent of cytoskeleton 7/1802 112/18639 0.0625 0.646469200887902 0.92515695621351 0.999999999981986 GO:0042379 chemokine receptor binding 4/1802 72/18639 0.0555555555555556 0.574639289678135 0.926873944072142 0.999999999981986 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1802 26/18639 0.0384615384615385 0.397827200546401 0.929028587892731 0.999999999981986 GO:0008143 poly(A) binding 1/1802 26/18639 0.0384615384615385 0.397827200546401 0.929028587892731 0.999999999981986 GO:0008157 protein phosphatase 1 binding 1/1802 26/18639 0.0384615384615385 0.397827200546401 0.929028587892731 0.999999999981986 GO:0005245 voltage-gated calcium channel activity 2/1802 43/18639 0.0465116279069767 0.481093358800299 0.929498369324464 0.999999999981986 GO:0008081 phosphoric diester hydrolase activity 5/1802 87/18639 0.0574712643678161 0.594454437598071 0.932039638049776 0.999999999981986 GO:0005044 scavenger receptor activity 1/1802 27/18639 0.037037037037037 0.383092859785424 0.935899618066121 0.999999999981986 GO:0023026 MHC class II protein complex binding 1/1802 27/18639 0.037037037037037 0.383092859785424 0.935899618066121 0.999999999981986 GO:0035401 histone H3Y41 kinase activity 7/1802 115/18639 0.0608695652173913 0.629604786951696 0.936404702649819 0.999999999981986 GO:0140801 histone H2AXY142 kinase activity 7/1802 115/18639 0.0608695652173913 0.629604786951696 0.936404702649819 0.999999999981986 GO:0015171 amino acid transmembrane transporter activity 6/1802 102/18639 0.0588235294117647 0.608441600835673 0.937582142978785 0.999999999981986 GO:0020037 heme binding 9/1802 142/18639 0.0633802816901408 0.655574400900408 0.939413342725195 0.999999999981986 GO:0005539 glycosaminoglycan binding 17/1802 242/18639 0.0702479338842975 0.726610010915328 0.939950197535364 0.999999999981986 GO:0042605 peptide antigen binding 2/1802 45/18639 0.0444444444444444 0.459711431742508 0.940296376453057 0.999999999981986 GO:0045499 chemorepellent activity 1/1802 28/18639 0.0357142857142857 0.369410971935944 0.942105769379513 0.999999999981986 GO:0051393 alpha-actinin binding 1/1802 28/18639 0.0357142857142857 0.369410971935944 0.942105769379513 0.999999999981986 GO:0017022 myosin binding 4/1802 76/18639 0.0526315789473684 0.544395116537181 0.943975024021667 0.999999999981986 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1802 46/18639 0.0434782608695652 0.449717704965497 0.94508710546174 0.999999999981986 GO:0005262 calcium channel activity 8/1802 131/18639 0.0610687022900763 0.63166456269963 0.945404186718091 0.999999999981986 GO:0003785 actin monomer binding 1/1802 29/18639 0.0344827586206897 0.356672662558843 0.947711346918501 0.999999999981986 GO:0005416 amino acid:monoatomic cation symporter activity 1/1802 29/18639 0.0344827586206897 0.356672662558843 0.947711346918501 0.999999999981986 GO:0051861 glycolipid binding 1/1802 29/18639 0.0344827586206897 0.356672662558843 0.947711346918501 0.999999999981986 GO:0061135 endopeptidase regulator activity 12/1802 184/18639 0.0652173913043478 0.674576557448246 0.949305407781344 0.999999999981986 GO:0043178 alcohol binding 5/1802 92/18639 0.0543478260869565 0.562147131206872 0.950230116547665 0.999999999981986 GO:0033218 amide binding 17/1802 247/18639 0.0688259109311741 0.711901306240929 0.950851300309394 0.999999999981986 GO:0033612 receptor serine/threonine kinase binding 1/1802 30/18639 0.0333333333333333 0.344783573806881 0.952774439495227 0.999999999981986 GO:0048019 receptor antagonist activity 1/1802 30/18639 0.0333333333333333 0.344783573806881 0.952774439495227 0.999999999981986 GO:0015108 chloride transmembrane transporter activity 7/1802 121/18639 0.0578512396694215 0.598384714871447 0.954516066717669 0.999999999981986 GO:0005184 neuropeptide hormone activity 1/1802 31/18639 0.032258064516129 0.333661523038917 0.957347520264188 0.999999999981986 GO:0016411 acylglycerol O-acyltransferase activity 1/1802 31/18639 0.032258064516129 0.333661523038917 0.957347520264188 0.999999999981986 GO:0035254 glutamate receptor binding 2/1802 49/18639 0.0408163265306122 0.422183967926793 0.957356855047288 0.999999999981986 GO:0038024 cargo receptor activity 3/1802 65/18639 0.0461538461538462 0.477392640655682 0.957404422242692 0.999999999981986 GO:0008509 monoatomic anion transmembrane transporter activity 9/1802 149/18639 0.0604026845637584 0.624775603542671 0.957719914930114 0.999999999981986 GO:0004867 serine-type endopeptidase inhibitor activity 5/1802 95/18639 0.0526315789473684 0.544395116537181 0.958897942683071 0.999999999981986 GO:0001618 virus receptor activity 4/1802 81/18639 0.0493827160493827 0.510790479713898 0.96019151697168 0.999999999981986 GO:0015101 organic cation transmembrane transporter activity 4/1802 81/18639 0.0493827160493827 0.510790479713898 0.96019151697168 0.999999999981986 GO:0048020 CCR chemokine receptor binding 2/1802 50/18639 0.04 0.413740288568258 0.960828101286789 0.999999999981986 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1802 32/18639 0.03125 0.323234600443951 0.961477989335767 0.999999999981986 GO:0160041 neuropeptide activity 1/1802 32/18639 0.03125 0.323234600443951 0.961477989335767 0.999999999981986 GO:0140272 exogenous protein binding 4/1802 82/18639 0.0487804878048781 0.504561327522265 0.962861640506326 0.999999999981986 GO:0005319 lipid transporter activity 11/1802 178/18639 0.0617977528089888 0.639205502001521 0.96342973807923 0.999999999981986 GO:0046906 tetrapyrrole binding 9/1802 152/18639 0.0592105263157895 0.612444506104329 0.96392379871862 0.999999999981986 GO:0005030 neurotrophin receptor activity 2/1802 51/18639 0.0392156862745098 0.405627733890448 0.964027203735735 0.999999999981986 GO:0016597 amino acid binding 2/1802 51/18639 0.0392156862745098 0.405627733890448 0.964027203735735 0.999999999981986 GO:0019956 chemokine binding 1/1802 33/18639 0.0303030303030303 0.31343961255171 0.965208663986003 0.999999999981986 GO:0140311 protein sequestering activity 1/1802 33/18639 0.0303030303030303 0.31343961255171 0.965208663986003 0.999999999981986 GO:0001540 amyloid-beta binding 4/1802 83/18639 0.0481927710843374 0.498482275383443 0.96536462667075 0.999999999981986 GO:0005254 chloride channel activity 4/1802 83/18639 0.0481927710843374 0.498482275383443 0.96536462667075 0.999999999981986 GO:0003777 microtubule motor activity 3/1802 68/18639 0.0441176470588235 0.456331200626755 0.966071975847137 0.999999999981986 GO:0004713 protein tyrosine kinase activity 8/1802 140/18639 0.0571428571428571 0.591057555097511 0.966600845515361 0.999999999981986 GO:0004519 endonuclease activity 7/1802 127/18639 0.0551181102362205 0.570114570861772 0.967851959390668 0.999999999981986 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1802 34/18639 0.0294117647058824 0.304220800417836 0.968578221521057 0.999999999981986 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1802 34/18639 0.0294117647058824 0.304220800417836 0.968578221521057 0.999999999981986 GO:0019825 oxygen binding 1/1802 34/18639 0.0294117647058824 0.304220800417836 0.968578221521057 0.999999999981986 GO:0017046 peptide hormone binding 2/1802 53/18639 0.0377358490566038 0.390321026951186 0.969688187845479 0.999999999981986 GO:0005343 organic acid:sodium symporter activity 1/1802 35/18639 0.0285714285714286 0.295528777548755 0.971621599366747 0.999999999981986 GO:0016229 steroid dehydrogenase activity 1/1802 35/18639 0.0285714285714286 0.295528777548755 0.971621599366747 0.999999999981986 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1802 36/18639 0.0277777777777778 0.287319644839068 0.974370356512583 0.999999999981986 GO:1901681 sulfur compound binding 18/1802 275/18639 0.0654545454545455 0.677029563111694 0.974382364491046 0.999999999981986 GO:0098632 cell-cell adhesion mediator activity 2/1802 55/18639 0.0363636363636364 0.376127535062052 0.974485182000733 0.999999999981986 GO:0008201 heparin binding 10/1802 172/18639 0.0581395348837209 0.601366698500374 0.97470542865619 0.999999999981986 GO:0005253 monoatomic anion channel activity 5/1802 103/18639 0.0485436893203883 0.502112000689633 0.975689440386833 0.999999999981986 GO:0170055 lipid transmembrane transporter activity 2/1802 56/18639 0.0357142857142857 0.369410971935944 0.976599777297028 0.999999999981986 GO:0042805 actinin binding 1/1802 37/18639 0.027027027027027 0.279554249032606 0.976853000041278 0.999999999981986 GO:0004521 RNA endonuclease activity 3/1802 73/18639 0.0410958904109589 0.425075638939991 0.976928640492193 0.999999999981986 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/1802 89/18639 0.0449438202247191 0.464876728728379 0.977368480315896 0.999999999981986 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/1802 89/18639 0.0449438202247191 0.464876728728379 0.977368480315896 0.999999999981986 GO:0004866 endopeptidase inhibitor activity 9/1802 161/18639 0.0559006211180124 0.578208477812782 0.977925700101699 0.999999999981986 GO:0004601 peroxidase activity 2/1802 57/18639 0.0350877192982456 0.362930077691454 0.9785442702207 0.999999999981986 GO:0140793 histone H2AXY142 phosphatase activity 4/1802 90/18639 0.0444444444444444 0.459711431742508 0.978940918318654 0.999999999981986 GO:0005109 frizzled binding 1/1802 38/18639 0.0263157894736842 0.27219755826859 0.979095280114691 0.999999999981986 GO:0008083 growth factor activity 9/1802 162/18639 0.0555555555555556 0.574639289678135 0.979126292524552 0.999999999981986 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/1802 59/18639 0.0338983050847458 0.350627363193439 0.981974418618233 0.999999999981986 GO:0070888 E-box binding 2/1802 59/18639 0.0338983050847458 0.350627363193439 0.981974418618233 0.999999999981986 GO:0071855 neuropeptide receptor binding 1/1802 40/18639 0.025 0.258587680355161 0.982949539120752 0.999999999981986 GO:0030414 peptidase inhibitor activity 9/1802 169/18639 0.0532544378698225 0.550837662295017 0.9859879646167 0.999999999981986 GO:0051879 Hsp90 protein binding 1/1802 42/18639 0.0238095238095238 0.246273981290629 0.986093498948113 0.999999999981986 GO:0004896 cytokine receptor activity 4/1802 96/18639 0.0416666666666667 0.430979467258602 0.986411403548301 0.999999999981986 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1802 43/18639 0.0232558139534884 0.24054667940015 0.987441002034391 0.999999999981986 GO:0004725 protein tyrosine phosphatase activity 4/1802 98/18639 0.0408163265306122 0.422183967926793 0.988283235314942 0.999999999981986 GO:0019955 cytokine binding 7/1802 144/18639 0.0486111111111111 0.502809378468368 0.988637972713538 0.999999999981986 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/1802 45/18639 0.0222222222222222 0.229855715871254 0.989757128916933 0.999999999981986 GO:0140359 ABC-type transporter activity 1/1802 47/18639 0.0212765957446809 0.22007462157886 0.99164630916991 0.999999999981986 GO:0015103 inorganic anion transmembrane transporter activity 8/1802 165/18639 0.0484848484848485 0.501503380082736 0.992422452592726 0.999999999981986 GO:0038187 pattern recognition receptor activity 1/1802 48/18639 0.0208333333333333 0.215489733629301 0.992455977353851 0.999999999981986 GO:0005004 GPI-linked ephrin receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0005008 hepatocyte growth factor receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0005009 insulin receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0005011 macrophage colony-stimulating factor receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0005020 stem cell factor receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0008288 boss receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0036332 placental growth factor receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0038062 protein tyrosine kinase collagen receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0060175 brain-derived neurotrophic factor receptor activity 1/1802 49/18639 0.0204081632653061 0.211091983963397 0.993187209068571 0.999999999981986 GO:0005006 epidermal growth factor receptor activity 1/1802 50/18639 0.02 0.206870144284129 0.993847599023301 0.999999999981986 GO:0005007 fibroblast growth factor receptor activity 1/1802 50/18639 0.02 0.206870144284129 0.993847599023301 0.999999999981986 GO:0005017 platelet-derived growth factor receptor activity 1/1802 50/18639 0.02 0.206870144284129 0.993847599023301 0.999999999981986 GO:0005019 platelet-derived growth factor beta-receptor activity 1/1802 50/18639 0.02 0.206870144284129 0.993847599023301 0.999999999981986 GO:0005010 insulin-like growth factor receptor activity 1/1802 51/18639 0.0196078431372549 0.202813866945224 0.994444006929053 0.999999999981986 GO:0005021 vascular endothelial growth factor receptor activity 1/1802 51/18639 0.0196078431372549 0.202813866945224 0.994444006929053 0.999999999981986 GO:0005003 ephrin receptor activity 1/1802 53/18639 0.0188679245283019 0.195160513475593 0.995469060147174 0.999999999981986 GO:0005005 transmembrane-ephrin receptor activity 1/1802 53/18639 0.0188679245283019 0.195160513475593 0.995469060147174 0.999999999981986 GO:0038064 collagen receptor activity 1/1802 53/18639 0.0188679245283019 0.195160513475593 0.995469060147174 0.999999999981986 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/1802 54/18639 0.0185185185185185 0.191546429892712 0.99590835604811 0.999999999981986 GO:0098631 cell adhesion mediator activity 2/1802 76/18639 0.0263157894736842 0.27219755826859 0.996025705871034 0.999999999981986 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 31/1802 484/18639 0.0640495867768595 0.662497362893387 0.996204460500109 0.999999999981986 GO:0003730 mRNA 3'-UTR binding 14/1802 262/18639 0.0534351145038168 0.552706492362176 0.996291149638275 0.999999999981986 GO:0019199 transmembrane receptor protein kinase activity 2/1802 78/18639 0.0256410256410256 0.265218133697601 0.996683558769235 0.999999999981986 GO:0005179 hormone activity 5/1802 132/18639 0.0378787878787879 0.391799515689638 0.996875254091902 0.999999999981986 GO:0015370 solute:sodium symporter activity 2/1802 79/18639 0.0253164556962025 0.261860942131809 0.996971074189368 0.999999999981986 GO:0001216 DNA-binding transcription activator activity 31/1802 491/18639 0.0631364562118126 0.653052390306313 0.997172456009041 0.999999999981986 GO:0001664 G protein-coupled receptor binding 16/1802 297/18639 0.0538720538720539 0.557225977869707 0.99752662828243 0.999999999981986 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/1802 60/18639 0.0166666666666667 0.172391786903441 0.997781280672494 0.999999999981986 GO:0140375 immune receptor activity 6/1802 156/18639 0.0384615384615385 0.397827200546401 0.998227423327634 0.999999999981986 GO:0004497 monooxygenase activity 3/1802 106/18639 0.0283018867924528 0.29274077021339 0.998446217439194 0.999999999981986 GO:0016500 protein-hormone receptor activity 1/1802 67/18639 0.0149253731343284 0.154380704689648 0.998913840971379 0.999999999981986 GO:0042626 ATPase-coupled transmembrane transporter activity 2/1802 98/18639 0.0204081632653061 0.211091983963397 0.999471327238986 0.999999999981986 GO:0005125 cytokine activity 8/1802 234/18639 0.0341880341880342 0.353624178263468 0.999933810849091 0.999999999981986 GO:0015081 sodium ion transmembrane transporter activity 4/1802 164/18639 0.024390243902439 0.252280663761133 0.999942503975811 0.999999999981986 GO:0001653 peptide receptor activity 2/1802 128/18639 0.015625 0.161617300221976 0.999968538041397 0.999999999981986 GO:0005244 voltage-gated monoatomic ion channel activity 4/1802 173/18639 0.023121387283237 0.239156236166623 0.999973392512497 0.999999999981986 GO:0003823 antigen binding 4/1802 174/18639 0.0229885057471264 0.237781775039228 0.999975587659829 0.999999999981986 GO:0046873 metal ion transmembrane transporter activity 21/1802 450/18639 0.0466666666666667 0.482697003329634 0.999976611531352 0.999999999981986 GO:0022832 voltage-gated channel activity 4/1802 175/18639 0.0228571428571429 0.236423022039004 0.999977603819557 0.999999999981986 GO:0015079 potassium ion transmembrane transporter activity 3/1802 160/18639 0.01875 0.193940760266371 0.999986672951436 0.999999999981986 GO:0022843 voltage-gated monoatomic cation channel activity 2/1802 143/18639 0.013986013986014 0.144664436562328 0.999992488396366 0.999999999981986 GO:0008528 G protein-coupled peptide receptor activity 1/1802 122/18639 0.00819672131147541 0.0847828460180856 0.999996071329481 0.999999999981986 GO:0005261 monoatomic cation channel activity 11/1802 341/18639 0.032258064516129 0.333661523038917 0.999998971542835 0.999999999981986 GO:0005216 monoatomic ion channel activity 17/1802 448/18639 0.0379464285714286 0.392499157681941 0.999999443800535 0.999999999981986 GO:0022834 ligand-gated channel activity 2/1802 188/18639 0.0106382978723404 0.11003731078943 0.999999903727286 0.999999999981986 GO:0015276 ligand-gated monoatomic ion channel activity 1/1802 186/18639 0.00537634408602151 0.0556102538398196 0.999999994461092 0.999999999981986 GO:0022836 gated channel activity 6/1802 318/18639 0.0188679245283019 0.195160513475593 0.999999996821854 0.999999999981986 GO:0045182 translation regulator activity 7/1802 356/18639 0.0196629213483146 0.203383568818666 0.999999999286798 0.999999999981986 GO:0030371 translation repressor activity 4/1802 329/18639 0.0121580547112462 0.125756926616492 0.999999999981986 0.999999999981986