category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 57/128 238/9376 17.5430672268908 CFD/RPL3/RPS4X/RPL10/RPS2/RPL7A/RPL13A/RPS3/RPS18/RPS27/RPL9/RPL6/RPLP0/RPL18A/RPS9/RPL12/RPL5/NFKBIA/RPS29/RPL23A/RPL13/RPS6/RPL18/RPS5/RPS23/RPS14/RPL8/RPL10A/RPL29/RPL37A/RPL11/RPL15/RPL27A/RPS28/RPL37/RPS3A/RPL7/RPS7/RPS8/RPS13/RPL30/RPS16/RPL17/JUN/RPS20/RPS19/RPS17/RPL22/RPL39/RPLP1/RPL36/RPL24/RPS10/RPS21/RPL32/RPL41/RPS11 30.4120467041758 Genetic Information Processing Translation hsa03010 Ribosome 55/128 222/9376 18.1475225225225 RPL3/RPS4X/RPL10/RPS2/RPL7A/RPL13A/RPS3/RPS18/RPS27/RPL9/RPL6/RPLP0/RPL18A/RPS9/RPL12/RPL5/RPS29/RPL23A/RPL13/RACK1/RPS6/RPL18/RPS5/RPS23/RPS14/RPL8/RPL10A/RPL29/RPL37A/RPL11/RPL15/RPL27A/RPS28/RPL37/RPS3A/RPL7/RPS7/RPS8/RPS13/RPL30/RPS16/RPL17/RPS20/RPS19/RPS17/RPL22/RPL39/RPLP1/RPL36/RPL24/RPS10/RPS21/RPL32/RPL41/RPS11 30.4185933895088 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 15/128 205/9376 5.35975609756098 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/COL3A1/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/COL1A1/MT-ND2/MT-ATP8/COL1A2 7.42501764474503 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 12/128 138/9376 6.3695652173913 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/MT-ND2/MT-ATP8 7.47577803750531 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 15/128 227/9376 4.84030837004405 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/NFKBIA/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/MT-ND2/SOD2/JUN/MT-ATP8 6.89062992894267 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 16/128 268/9376 4.37313432835821 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/UBB/MT-ND2/UBC/MT-ATP8/TXN/SNCA 6.59107471861869 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 13/128 235/9376 4.05212765957447 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/RPS6/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/MT-ND2/MT-ATP8 5.57450723938504 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 14/128 308/9376 3.32954545454545 MT-CO3/MT-CYB/TGM2/MT-ND3/MT-CO1/MT-ND1/MT-ND5/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/MT-ND2/SOD2/MT-ATP8 4.89054775355905 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 7/128 89/9376 5.76123595505618 COL1A1/COL6A1/SPP1/FN1/COL6A3/COL6A2/COL1A2 5.30937863153655 Human Diseases Neurodegenerative disease hsa05020 Prion disease 12/128 275/9376 3.19636363636364 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/MT-ND2/MT-ATP8 4.34903344011312 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 7/128 100/9376 5.1275 CCL4L2/CCL4/XCL1/XCL2/CXCL12/IL10RA/CCL3L1 4.88172627672021 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 14/128 368/9376 2.7866847826087 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/MT-ND2/MT-ATP8/HNRNPA1/MAP1LC3B 4.11362190156922 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 16/128 480/9376 2.44166666666667 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/UBB/MT-ND2/UBC/MT-ATP8/SNCA/MAP1LC3B 3.81465091527219 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 10/128 233/9376 3.14377682403433 FBLN1/COL3A1/VCAN/COL1A1/COL6A1/FN1/COL6A3/COL6A2/COL1A2/VIM 3.89834153067365 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 13/128 388/9376 2.45425257731959 MT-CO3/MT-CYB/MT-ND3/MT-CO1/MT-ND1/MT-ND5/MT-CO2/MT-ATP6/MT-ND4L/MT-ND4/MT-ND2/MT-ATP8/SNCA 3.44184164881214 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 6/128 103/9376 4.26699029126214 COL3A1/COL1A1/COL6A1/COL6A3/COL6A2/COL1A2 3.92213952260652 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 6/128 105/9376 4.18571428571429 CCL4L2/NFKBIA/CCL4/TNFAIP3/CXCL12/GADD45B 3.86193441840063 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 6/128 109/9376 4.03211009174312 CCL4L2/NFKBIA/CCL4/JUN/SPP1/CCL3L1 3.74589281081107 NA NA hsa04518 Integrin signaling 7/128 154/9376 3.32954545454545 COL1A1/COL6A1/SPP1/FN1/COL6A3/COL6A2/COL1A2 3.42914384245498 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 8/128 203/9376 2.88669950738916 COL1A1/COL6A1/JUN/SPP1/FN1/COL6A3/COL6A2/COL1A2 3.19714085892758 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 4/128 56/9376 5.23214285714286 EEF1A1/EEF1G/NFKBIA/CLK1 3.73691387565178 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 5/128 101/9376 3.62623762376238 COL3A1/COL1A1/JUN/FN1/COL1A2 3.12179556304034 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 6/128 149/9376 2.9496644295302 MT-ND3/MT-ND1/MT-ND5/MT-ND4L/MT-ND4/MT-ND2 2.82221083391453 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 7/128 193/9376 2.65673575129534 CCL4L2/NFKBIA/CCL4/XCL1/XCL2/CXCL12/CCL3L1 2.73593842526863 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 9/128 298/9376 2.21224832214765 CCL4L2/CCL4/CSH1/XCL1/XCL2/IL32/CXCL12/IL10RA/CCL3L1 2.50190806455833 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 4/128 78/9376 3.75641025641026 EEF1A1/NFKBIA/HLA-DRB5/JUN 2.87582927340358 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 4/128 87/9376 3.36781609195402 MT-CO3/MT-CYB/MT-CO1/MT-CO2 2.61029640414094 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 5/128 130/9376 2.81730769230769 NFKBIA/COL3A1/COL1A1/JUN/COL1A2 2.45465188002574 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 4/128 95/9376 3.08421052631579 HLA-DRB5/JUN/CXCL12/CCL3L1 2.4019983999366 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 4/128 103/9376 2.84466019417476 COL3A1/COL1A1/FN1/COL1A2 2.2145810083068 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 4/128 105/9376 2.79047619047619 UBB/UBC/JUN/MAP1LC3B 2.17053414247928 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 9/128 362/9376 1.82113259668508 RPS6/CSH1/COL1A1/COL6A1/SPP1/FN1/COL6A3/COL6A2/COL1A2 1.8744571358523 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 6/128 205/9376 2.14390243902439 NFKBIA/TNFAIP3/HLA-DRB5/JUN/GADD45B/VIM 1.94815847574009 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 5/128 157/9376 2.3328025477707 MT-CO3/MT-CYB/MT-CO1/MT-CO2/JUN 1.98125531882277 Human Diseases Immune disease hsa05310 Asthma 2/128 32/9376 4.578125 HLA-DRB5/PRG2 2.38523292246696 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 6/128 227/9376 1.93612334801762 CCL4L2/NFKBIA/CCL4/CXCL12/IL10RA/CCL3L1 1.6796774991687 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 3/128 83/9376 2.64759036144578 CCL4L2/NFKBIA/CCL4 1.77368720336603 Cellular Processes Cell growth and death hsa04216 Ferroptosis 2/128 42/9376 3.48809523809524 FTL/MAP1LC3B 1.90118535164052 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 5/128 187/9376 1.95855614973262 NFKBIA/TNFAIP3/JUN/TXN/MAP1LC3B 1.55765383181857 Human Diseases Infectious disease: viral hsa05162 Measles 4/128 136/9376 2.15441176470588 NFKBIA/RACK1/TNFAIP3/JUN 1.59536817781575 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 5/128 196/9376 1.86862244897959 NFKBIA/UBB/UBC/JUN/MAP1LC3B 1.44578747067352 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 3/128 93/9376 2.36290322580645 NFKBIA/HLA-DRB5/JUN 1.55392134033257 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 3/128 93/9376 2.36290322580645 NFKBIA/FN1/GADD45B 1.55392134033257 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 3/128 94/9376 2.33776595744681 NFKBIA/TNFAIP3/JUN 1.53352195266224 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 5/128 204/9376 1.7953431372549 DDX5/RPS6/COL1A1/FN1/COL1A2 1.35115231981022 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 2/128 50/9376 2.93 HLA-DRB5/CXCL12 1.60976069108326 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 3/128 103/9376 2.13349514563107 NFKBIA/JUN/CCL3L1 1.36080175115694 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 2/128 54/9376 2.71296296296296 HLA-DRB5/CGA 1.48510450674799 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 7/128 333/9376 1.53978978978979 COL1A1/COL6A1/SPP1/FN1/COL6A3/COL6A2/COL1A2 1.17993267901012 Organismal Systems Immune system hsa04659 Th17 cell differentiation 3/128 109/9376 2.01605504587156 NFKBIA/HLA-DRB5/JUN 1.25524244719312 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 3/128 112/9376 1.96205357142857 NFKBIA/HLA-DRB5/IL10RA 1.20496853594525 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 3/128 119/9376 1.84663865546218 NFKBIA/TNFAIP3/JUN 1.09346063965733 Organismal Systems Endocrine system hsa04929 GnRH secretion 2/128 65/9376 2.25384615384615 CGA/SPP1 1.1933545122443 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 2/128 66/9376 2.21969696969697 HLA-DRB5/JUN 1.16981122565586 Organismal Systems Immune system hsa04611 Platelet activation 3/128 126/9376 1.74404761904762 COL3A1/COL1A1/COL1A2 0.989194857537925 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 2/128 71/9376 2.06338028169014 NFKBIA/JUN 1.05809899289159 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 2/128 72/9376 2.03472222222222 NFKBIA/DDX3X 1.03686421524828 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 5/128 253/9376 1.44762845849802 NFKBIA/UBB/UBC/JUN/MAP1LC3B 0.849133207019893 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 2/128 76/9376 1.92763157894737 UBC/PLIN2 0.955229132488432 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 2/128 77/9376 1.9025974025974 NFKBIA/GADD45B 0.935595298247531 Cellular Processes Cell growth and death hsa04210 Apoptosis 3/128 137/9376 1.60401459854015 NFKBIA/JUN/GADD45B 0.837841653854241 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 2/128 78/9376 1.87820512820513 FN1/DNM3 0.91625258245649 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 3/128 138/9376 1.59239130434783 NFKBIA/JUN/FN1 0.824756888753116 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 3/128 140/9376 1.56964285714286 RPS6/SPP1/MAP1LC3B 0.798898166159338 Cellular Processes Transport and catabolism hsa04146 Peroxisome 2/128 83/9376 1.76506024096386 SOD2/PRDX5 0.823613436297939 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 2/128 87/9376 1.68390804597701 JUN/GADD45B 0.753944835176629 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 4/128 216/9376 1.35648148148148 NFKBIA/SOD2/JUN/CCL3L1 0.623566571507867 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 2/128 90/9376 1.62777777777778 NFKBIA/JUN 0.704011196113927 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 2/128 91/9376 1.60989010989011 NFKBIA/JUN 0.687777628642337 Metabolism Carbohydrate metabolism hsa00640 Propanoate metabolism 1/128 32/9376 2.2890625 LDHA 0.85930880394552 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 2/128 93/9376 1.5752688172043 CGA/JUN 0.655895792566409 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 3/128 163/9376 1.34815950920245 NFKBIA/JUN/DDX3X 0.527519162818731 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 2/128 99/9376 1.47979797979798 CFD/HLA-DRB5 0.564597494442 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 1/128 37/9376 1.97972972972973 HBB 0.702463355128287 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/128 37/9376 1.97972972972973 GADD45B 0.702463355128287 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 3/128 169/9376 1.30029585798817 UBB/UBC/MAP1LC3B 0.463447277424519 Human Diseases Immune disease hsa05330 Allograft rejection 1/128 39/9376 1.87820512820513 HLA-DRB5 0.646533905996306 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 2/128 105/9376 1.3952380952381 NFKBIA/JUN 0.479133866557925 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 4/128 248/9376 1.18145161290323 RPS3/NFKBIA/JUN/TXN 0.340694851092658 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 2/128 110/9376 1.33181818181818 RPS6/LDHA 0.411829152772017 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 3/128 180/9376 1.22083333333333 NFKBIA/HLA-DRB5/SRSF5 0.351939580169355 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/128 44/9376 1.66477272727273 HLA-DRB5 0.51997070895344 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/128 45/9376 1.62777777777778 HLA-DRB5 0.496609259650887 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 2/128 115/9376 1.27391304347826 NACA/NR4A2 0.347695767458427 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/128 46/9376 1.59239130434783 FTL 0.473820101450387 Metabolism Carbohydrate metabolism hsa00620 Pyruvate metabolism 1/128 47/9376 1.55851063829787 LDHA 0.451574640360699 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 2/128 120/9376 1.22083333333333 NFKBIA/JUN 0.286424583621381 Metabolism Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis 1/128 49/9376 1.49489795918367 COLGALT2 0.408610410233555 Human Diseases Substance dependence hsa05030 Cocaine addiction 1/128 49/9376 1.49489795918367 JUN 0.408610410233555 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/128 50/9376 1.465 HBB 0.387843897074464 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 2/128 122/9376 1.20081967213115 NFKBIA/JUN 0.262656488574133 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 1/128 52/9376 1.40865384615385 CGA 0.347634477899892 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/128 52/9376 1.40865384615385 MYLIP 0.347634477899892 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 3/128 200/9376 1.09875 RPS3/NFKBIA/JUN 0.166070354286646 Organismal Systems Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption 1/128 53/9376 1.38207547169811 DNM3 0.328152685791938 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 1/128 54/9376 1.35648148148148 LDHA 0.309062289242149 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 3/128 205/9376 1.0719512195122 NFKBIA/JUN/DDX3X 0.122538752738449 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 2/128 133/9376 1.1015037593985 SOD2/GADD45B 0.13869735658149 Metabolism Nucleotide metabolism hsa00240 Pyrimidine metabolism 1/128 59/9376 1.24152542372881 NME2 0.218936173458215 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 1/128 59/9376 1.24152542372881 CGA 0.218936173458215 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/128 59/9376 1.24152542372881 GADD45B 0.218936173458215 Organismal Systems Digestive system hsa04978 Mineral absorption 1/128 61/9376 1.20081967213115 FTL 0.185117064176699 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 1/128 62/9376 1.18145161290323 SOD2 0.16863793415729 Metabolism Amino acid metabolism hsa00310 Lysine degradation 1/128 63/9376 1.16269841269841 COLGALT2 0.152431773191805 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 1/128 63/9376 1.16269841269841 PTGDS 0.152431773191805 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/128 63/9376 1.16269841269841 GADD45B 0.152431773191805 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 2/128 142/9376 1.03169014084507 UBB/UBC 0.0447651577190668 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 2/128 142/9376 1.03169014084507 NFKBIA/JUN 0.0447651577190668 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 2/128 142/9376 1.03169014084507 JUN/TXN 0.0447651577190668 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 3/128 224/9376 0.981026785714286 NFKBIA/HLA-DRB5/JUN -0.0338122154520187 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 3/128 226/9376 0.972345132743363 NFKBIA/CGA/JUN -0.0495087502105464 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 1/128 67/9376 1.09328358208955 LDHA 0.090148356467833 Human Diseases Cancer: specific types hsa05224 Breast cancer 2/128 148/9376 0.989864864864865 JUN/GADD45B -0.0146208735442365 Human Diseases Substance dependence hsa05031 Amphetamine addiction 1/128 69/9376 1.06159420289855 JUN 0.0604124209973452 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/128 70/9376 1.04642857142857 NFKBIA 0.0458690271723278 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/128 70/9376 1.04642857142857 JUN 0.0458690271723278 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/128 70/9376 1.04642857142857 HLA-DRB5 0.0458690271723278 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/128 71/9376 1.03169014084507 CGA 0.0315327514437891 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/128 71/9376 1.03169014084507 LDHA 0.0315327514437891 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 2/128 154/9376 0.951298701298701 JUN/EEF2 -0.0716894183091635 Human Diseases Cancer: specific types hsa05218 Melanoma 1/128 73/9376 1.00342465753425 GADD45B 0.00345568207777855 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/128 73/9376 1.00342465753425 GADD45B 0.00345568207777855 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/128 75/9376 0.976666666666667 GADD45B -0.0238676305809092 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/128 75/9376 0.976666666666667 CGA -0.0238676305809092 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 2/128 160/9376 0.915625 VCAN/HLA-DRB5 -0.12663952024959 Genetic Information Processing Transcription hsa03040 Spliceosome 3/128 243/9376 0.904320987654321 DDX5/SRSF5/HNRNPA1 -0.177778731919142 Human Diseases Cancer: specific types hsa05214 Glioma 1/128 76/9376 0.963815789473684 GADD45B -0.0372607108417472 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/128 77/9376 0.951298701298701 GADD45B -0.0504817606968093 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/128 78/9376 0.939102564102564 BTG1 -0.063535763017056 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/128 78/9376 0.939102564102564 JUN -0.063535763017056 Organismal Systems Nervous system hsa04721 Synaptic vesicle cycle 1/128 79/9376 0.927215189873418 DNM3 -0.076427489850593 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/128 80/9376 0.915625 RPS6 -0.0891615139843511 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/128 168/9376 0.872023809523809 FTL/TNFAIP3 -0.19691004717555 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 2/128 168/9376 0.872023809523809 CSH1/IL10RA -0.19691004717555 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/128 82/9376 0.893292682926829 NME2 -0.114173813014217 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/128 82/9376 0.893292682926829 HLA-DRB5 -0.114173813014217 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/128 173/9376 0.846820809248555 NFKBIA/HLA-DRB5 -0.23923505880067 Metabolism Global and overview maps hsa01232 Nucleotide metabolism 1/128 85/9376 0.861764705882353 NME2 -0.150613494901285 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 1/128 86/9376 0.851744186046512 JUN -0.162487446825125 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 2/128 178/9376 0.823033707865168 SFRP2/JUN -0.28042747560549 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/128 88/9376 0.832386363636364 CFD -0.185847315977356 Organismal Systems Aging hsa04211 Longevity regulating pathway 1/128 90/9376 0.813888888888889 SOD2 -0.208711283803686 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/128 181/9376 0.80939226519337 HLA-DRB5/IL10RA -0.304628585105502 Organismal Systems Development and regeneration hsa04360 Axon guidance 2/128 184/9376 0.796195652173913 CXCL12/EPHA4 -0.328461189159832 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 1/128 98/9376 0.747448979591837 NR4A2 -0.29566620965129 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/128 99/9376 0.73989898989899 JUN -0.306071273302768 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/128 99/9376 0.73989898989899 JUN -0.306071273302768 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/128 100/9376 0.7325 HLA-DRB5 -0.316380806546979 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 2/128 201/9376 0.728855721393035 DDX5/GADD45B -0.457153605772507 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/128 106/9376 0.691037735849057 NFKBIA -0.376344191146524 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 1/128 107/9376 0.684579439252336 LDHA -0.386039869138603 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/128 108/9376 0.678240740740741 EEF1A1 -0.395654975141118 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/128 109/9376 0.672018348623853 NFKBIA -0.405191128552181 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 3/128 300/9376 0.7325 DUSP2/JUN/GADD45B -0.553992496613899 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 2/128 214/9376 0.684579439252336 NFKBIA/JUN -0.549121508538959 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/128 116/9376 0.631465517241379 CXCL12 -0.469859858536332 NA NA hsa04081 Hormone signaling 2/128 219/9376 0.668949771689498 CSH1/CGA -0.583184609910375 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/128 122/9376 0.600409836065574 EEF2 -0.522632808897509 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/128 122/9376 0.600409836065574 CSH1 -0.522632808897509 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 1/128 128/9376 0.572265625 NME2 -0.57322079964548 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/128 232/9376 0.631465517241379 FN1/CXCL12 -0.668683683395796 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/128 138/9376 0.530797101449275 RPS6 -0.653247810969594 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/128 139/9376 0.526978417266187 JUN -0.660981946518604 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/128 143/9376 0.512237762237762 HLA-DRB5 -0.691467046996972 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/128 144/9376 0.508680555555556 NFKBIA -0.698978814352964 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 1/128 149/9376 0.491610738255034 DNM3 -0.7359121193426 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/128 150/9376 0.488333333333333 GADD45B -0.743177823812033 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/128 154/9376 0.475649350649351 NME2 -0.771856070461993 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/128 155/9376 0.47258064516129 HLA-DRB5 -0.778932121740802 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/128 156/9376 0.469551282051282 NFKBIA -0.78597178376125 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 3/128 370/9376 0.593918918918919 GZMA/CSH1/CGA -0.937593007637655 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/128 157/9376 0.46656050955414 DUSP2 -0.792975545765388 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/128 157/9376 0.46656050955414 GADD45B -0.792975545765388 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/128 158/9376 0.463607594936709 GADD45B -0.799943887043282 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/128 158/9376 0.463607594936709 RPS6 -0.799943887043282 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/128 170/9376 0.430882352941176 JUN -0.8809631451624 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/128 170/9376 0.430882352941176 GADD45B -0.8809631451624 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 1/128 174/9376 0.420977011494253 DNAJA1 -0.906976487827992 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/128 217/9376 0.337557603686636 JUN -1.16150389207739 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/128 250/9376 0.293 DNM3 -1.33295625942685 NA NA hsa04519 Cadherin signaling 2/128 404/9376 0.362623762376238 NFKBIA/VIM -1.54066646952624 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/128 323/9376 0.226780185758514 VIM -1.66369874127681