ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 55/165 175/18639 0.314285714285714 35.5028571428571 3.24992707797962e-72 1.29347097703589e-69 GO:0019843 rRNA binding 16/165 65/18639 0.246153846153846 27.8064335664336 3.02138140445706e-19 6.01254899486954e-17 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 10/165 68/18639 0.147058823529412 16.6122994652406 4.1998507411879e-10 5.57180198330928e-08 GO:0048027 mRNA 5'-UTR binding 7/165 24/18639 0.291666666666667 32.9477272727273 1.14329019801881e-09 1.13757374702871e-07 GO:0019838 growth factor binding 12/165 136/18639 0.0882352941176471 9.96737967914439 3.04519249384779e-09 2.42397322510284e-07 GO:1990948 ubiquitin ligase inhibitor activity 5/165 11/18639 0.454545454545455 51.3471074380165 2.26419328739294e-08 1.50191488063732e-06 GO:0005201 extracellular matrix structural constituent 12/165 168/18639 0.0714285714285714 8.06883116883117 3.32197054868549e-08 1.88877754053832e-06 GO:0009055 electron transfer activity 10/165 116/18639 0.0862068965517241 9.73824451410658 8.18852825740538e-08 3.83560245565537e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 10/165 118/18639 0.0847457627118644 9.57318952234206 9.63572666018896e-08 3.83560245565537e-06 GO:0015078 proton transmembrane transporter activity 12/165 185/18639 0.0648648648648649 7.32737100737101 9.63719209963662e-08 3.83560245565537e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/165 15/18639 0.333333333333333 37.6545454545455 1.43010239141292e-07 5.17437047074857e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/165 41/18639 0.146341463414634 16.5312638580931 1.52853434030089e-06 5.06963889533129e-05 GO:0048407 platelet-derived growth factor binding 4/165 11/18639 0.363636363636364 41.0776859504132 1.86176273867672e-06 5.69985823071797e-05 GO:0015399 primary active transmembrane transporter activity 10/165 166/18639 0.0602409638554217 6.80503833515882 2.28293633416963e-06 5.83975517384738e-05 GO:0003954 NADH dehydrogenase activity 6/165 44/18639 0.136363636363636 15.404132231405 2.34764027089342e-06 5.83975517384738e-05 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/165 44/18639 0.136363636363636 15.404132231405 2.34764027089342e-06 5.83975517384738e-05 GO:0008135 translation factor activity, RNA binding 7/165 83/18639 0.0843373493975904 9.52705366922234 8.85178003864832e-06 0.000198513055966634 GO:0045296 cadherin binding 13/165 334/18639 0.0389221556886228 4.39678824169842 8.97797740552618e-06 0.000198513055966634 GO:0180051 translation factor activity 7/165 84/18639 0.0833333333333333 9.41363636363636 9.58526032201638e-06 0.000200785979376975 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/165 58/18639 0.103448275862069 11.6858934169279 1.21524686379176e-05 0.00024183412589456 GO:0055106 ubiquitin-protein transferase regulator activity 5/165 36/18639 0.138888888888889 15.6893939393939 1.54477771514715e-05 0.000292772157442174 GO:0003746 translation elongation factor activity 4/165 18/18639 0.222222222222222 25.1030303030303 1.64474738673249e-05 0.000297549754508878 GO:0005520 insulin-like growth factor binding 4/165 19/18639 0.210526315789474 23.7818181818182 2.06899728133177e-05 0.000358026486073933 GO:0008009 chemokine activity 5/165 45/18639 0.111111111111111 12.5515151515152 4.69477270827254e-05 0.000778549807455195 GO:0005178 integrin binding 8/165 161/18639 0.0496894409937888 5.61309994353473 9.48616817488189e-05 0.0015101979734412 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/165 88/18639 0.0681818181818182 7.70206611570248 0.000130769408105681 0.00199874798485932 GO:0001968 fibronectin binding 4/165 30/18639 0.133333333333333 15.0618181818182 0.0001355934562593 0.00199874798485932 GO:0016504 peptidase activator activity 5/165 57/18639 0.087719298245614 9.90909090909091 0.000147708390089503 0.00205866581192884 GO:0008201 heparin binding 8/165 172/18639 0.0465116279069767 5.25412262156448 0.00015000328780386 0.00205866581192884 GO:0031994 insulin-like growth factor I binding 3/165 13/18639 0.230769230769231 26.0685314685315 0.000182527050099939 0.00242152553132586 GO:0004129 cytochrome-c oxidase activity 3/165 15/18639 0.2 22.5927272727273 0.000286625614250944 0.00367990304747987 GO:0005539 glycosaminoglycan binding 9/165 242/18639 0.0371900826446281 4.20112697220135 0.000312564802263281 0.00388752472814956 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/165 16/18639 0.1875 21.1806818181818 0.000350481056278063 0.00422701395147482 GO:0042379 chemokine receptor binding 5/165 72/18639 0.0694444444444444 7.84469696969697 0.000443657327586517 0.00519340048174806 GO:0048020 CCR chemokine receptor binding 4/165 50/18639 0.08 9.03709090909091 0.000993128647142702 0.0112932914732227 GO:1901681 sulfur compound binding 8/165 275/18639 0.0290909090909091 3.28621487603306 0.00317586688365618 0.03511097276931 GO:0005518 collagen binding 4/165 72/18639 0.0555555555555556 6.27575757575758 0.00381721077028945 0.0410608077452757 GO:0004857 enzyme inhibitor activity 10/165 416/18639 0.0240384615384615 2.71547202797203 0.00401105961351708 0.0420105717415736 GO:0097371 MDM2/MDM4 family protein binding 2/165 12/18639 0.166666666666667 18.8272727272727 0.00484990289551569 0.0482681901095115 GO:0005125 cytokine activity 7/165 234/18639 0.0299145299145299 3.37925407925408 0.00489262783967583 0.0482681901095115 GO:0043021 ribonucleoprotein complex binding 6/165 177/18639 0.0338983050847458 3.82927580893683 0.00497235124243711 0.0482681901095115 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/165 40/18639 0.075 8.47227272727273 0.00529338187736281 0.0491993083123434 GO:0046332 SMAD binding 4/165 79/18639 0.0506329113924051 5.71967779056387 0.00531550315937378 0.0491993083123434 GO:0031625 ubiquitin protein ligase binding 8/165 302/18639 0.0264900662251656 2.99241420830825 0.00555639949795728 0.050260159095159 GO:0016209 antioxidant activity 4/165 86/18639 0.0465116279069767 5.25412262156448 0.00716383039870154 0.0619885750377039 GO:0002020 protease binding 5/165 136/18639 0.0367647058823529 4.15307486631016 0.00726641044143531 0.0619885750377039 GO:0031386 protein tag activity 2/165 15/18639 0.133333333333333 15.0618181818182 0.00758259955482188 0.0619885750377039 GO:0141047 molecular tag activity 2/165 15/18639 0.133333333333333 15.0618181818182 0.00758259955482188 0.0619885750377039 GO:0022804 active transmembrane transporter activity 10/165 457/18639 0.0218818380743982 2.4718519992043 0.00763175923831028 0.0619885750377039 GO:0044389 ubiquitin-like protein ligase binding 8/165 322/18639 0.0248447204968944 2.80654997176736 0.00805766312314888 0.0641389984602651 GO:0003743 translation initiation factor activity 3/165 51/18639 0.0588235294117647 6.64491978609626 0.0103956792304968 0.0795669294949559 GO:0030544 Hsp70 protein binding 3/165 51/18639 0.0588235294117647 6.64491978609626 0.0103956792304968 0.0795669294949559 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/165 18/18639 0.111111111111111 12.5515151515152 0.0108586571825041 0.0815423690308795 GO:0043024 ribosomal small subunit binding 2/165 20/18639 0.1 11.2963636363636 0.0133296234156263 0.0982442614707275 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/165 21/18639 0.0952380952380952 10.7584415584416 0.0146479239789898 0.105997704429781 GO:0061134 peptidase regulator activity 6/165 226/18639 0.0265486725663717 2.99903459372486 0.0154647017899667 0.109909844864406 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/165 22/18639 0.0909090909090909 10.2694214876033 0.0160200208068831 0.11185909265157 GO:0001664 G protein-coupled receptor binding 7/165 297/18639 0.0235690235690236 2.66244260789715 0.0167531895841451 0.114961542318789 GO:0017134 fibroblast growth factor binding 2/165 23/18639 0.0869565217391304 9.82292490118577 0.0174448702071055 0.116586237802289 GO:0043022 ribosome binding 4/165 112/18639 0.0357142857142857 4.03441558441558 0.0175758147440637 0.116586237802289 GO:0004252 serine-type endopeptidase activity 5/165 176/18639 0.0284090909090909 3.20919421487603 0.0202943890847485 0.132412571405408 GO:0008198 ferrous iron binding 2/165 26/18639 0.0769230769230769 8.68951048951049 0.0220257069229864 0.139146529449978 GO:0070412 R-SMAD binding 2/165 26/18639 0.0769230769230769 8.68951048951049 0.0220257069229864 0.139146529449978 GO:0015252 proton channel activity 2/165 27/18639 0.0740740740740741 8.36767676767677 0.0236514085498547 0.147082196919409 GO:0008236 serine-type peptidase activity 5/165 194/18639 0.0257731958762887 2.91143392689784 0.029306528157175 0.179446126254702 GO:0005179 hormone activity 4/165 132/18639 0.0303030303030303 3.42314049586777 0.0298983159215948 0.18029590510295 GO:0003724 RNA helicase activity 3/165 77/18639 0.038961038961039 4.40118063754427 0.0309379663263514 0.182291217578636 GO:0051087 protein-folding chaperone binding 4/165 134/18639 0.0298507462686567 3.37204884667571 0.0313517619931018 0.182291217578636 GO:0017171 serine hydrolase activity 5/165 198/18639 0.0252525252525253 2.85261707988981 0.0316032512887586 0.182291217578636 GO:0031369 translation initiation factor binding 2/165 32/18639 0.0625 7.06022727272727 0.0324770051686768 0.184654972244762 GO:0008186 ATP-dependent activity, acting on RNA 3/165 79/18639 0.0379746835443038 4.2897583429229 0.0330244933074323 0.185123216005043 GO:0005126 cytokine receptor binding 6/165 275/18639 0.0218181818181818 2.46466115702479 0.035895466765604 0.195316579577037 GO:0015035 protein-disulfide reductase activity 2/165 34/18639 0.0588235294117647 6.64491978609626 0.036315142936434 0.195316579577037 GO:0019825 oxygen binding 2/165 34/18639 0.0588235294117647 6.64491978609626 0.036315142936434 0.195316579577037 GO:0015036 disulfide oxidoreductase activity 2/165 40/18639 0.05 5.64818181818182 0.0487927790360342 0.258927014084555 GO:0035198 miRNA binding 2/165 42/18639 0.0476190476190476 5.37922077922078 0.0532505711924955 0.278864833350174 GO:0008083 growth factor activity 4/165 162/18639 0.0246913580246914 2.78922558922559 0.05602836013983 0.289601134229251 GO:0019888 protein phosphatase regulator activity 3/165 107/18639 0.0280373831775701 3.16720475785896 0.0695047090318623 0.352171097212424 GO:0035254 glutamate receptor binding 2/165 49/18639 0.0408163265306122 4.61076066790352 0.069903308240657 0.352171097212424 GO:0004864 protein phosphatase inhibitor activity 2/165 53/18639 0.0377358490566038 4.26277873070326 0.0800819652571982 0.366278906861987 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/165 54/18639 0.037037037037037 4.18383838383838 0.0826948796399981 0.366278906861987 GO:0003730 mRNA 3'-UTR binding 5/165 262/18639 0.0190839694656489 2.1557945870923 0.0837241118749742 0.366278906861987 GO:0005131 growth hormone receptor binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0008190 eukaryotic initiation factor 4E binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0030957 Tat protein binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0031720 haptoglobin binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0032356 oxidized DNA binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0035256 G protein-coupled glutamate receptor binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0035374 chondroitin sulfate binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0051880 G-quadruplex DNA binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0070513 death domain binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0098505 G-rich strand telomeric DNA binding 1/165 10/18639 0.1 11.2963636363636 0.0850993385667547 0.366278906861987 GO:0019208 phosphatase regulator activity 3/165 117/18639 0.0256410256410256 2.8965034965035 0.0855877847692583 0.366278906861987 GO:0019212 phosphatase inhibitor activity 2/165 56/18639 0.0357142857142857 4.03441558441558 0.0879979047772318 0.368049603712582 GO:0004601 peroxidase activity 2/165 57/18639 0.0350877192982456 3.96363636363636 0.0906867100686539 0.368049603712582 GO:0051082 unfolded protein binding 3/165 121/18639 0.0247933884297521 2.8007513148009 0.0924262980714877 0.368049603712582 GO:0008199 ferric iron binding 1/165 11/18639 0.0909090909090909 10.2694214876033 0.0932027584570595 0.368049603712582 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/165 11/18639 0.0909090909090909 10.2694214876033 0.0932027584570595 0.368049603712582 GO:0019215 intermediate filament binding 1/165 11/18639 0.0909090909090909 10.2694214876033 0.0932027584570595 0.368049603712582 GO:0050998 nitric-oxide synthase binding 1/165 11/18639 0.0909090909090909 10.2694214876033 0.0932027584570595 0.368049603712582 GO:0061980 regulatory RNA binding 2/165 58/18639 0.0344827586206897 3.89529780564263 0.0933995225501777 0.368049603712582 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/165 59/18639 0.0338983050847458 3.82927580893683 0.0961357128450301 0.371475861284679 GO:0036002 pre-mRNA binding 2/165 59/18639 0.0338983050847458 3.82927580893683 0.0961357128450301 0.371475861284679 GO:0035259 nuclear glucocorticoid receptor binding 1/165 12/18639 0.0833333333333333 9.41363636363636 0.101234836235381 0.380108158695111 GO:0035497 cAMP response element binding 1/165 12/18639 0.0833333333333333 9.41363636363636 0.101234836235381 0.380108158695111 GO:0043047 single-stranded telomeric DNA binding 1/165 12/18639 0.0833333333333333 9.41363636363636 0.101234836235381 0.380108158695111 GO:0030246 carbohydrate binding 5/165 280/18639 0.0178571428571429 2.01720779220779 0.103568224303785 0.385235077316883 GO:0005507 copper ion binding 2/165 63/18639 0.0317460317460317 3.58614718614719 0.107301982164757 0.391532307087838 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/165 13/18639 0.0769230769230769 8.68951048951049 0.109196196197864 0.391532307087838 GO:0004535 poly(A)-specific ribonuclease activity 1/165 13/18639 0.0769230769230769 8.68951048951049 0.109196196197864 0.391532307087838 GO:0140666 annealing activity 1/165 13/18639 0.0769230769230769 8.68951048951049 0.109196196197864 0.391532307087838 GO:0031072 heat shock protein binding 3/165 131/18639 0.0229007633587786 2.58695350451076 0.110461799274884 0.392533893851821 GO:0019207 kinase regulator activity 5/165 287/18639 0.0174216027874564 1.96800760215394 0.111865582660257 0.394004441582145 GO:0005344 oxygen carrier activity 1/165 14/18639 0.0714285714285714 8.06883116883117 0.117087457210822 0.405224417129628 GO:0098847 sequence-specific single stranded DNA binding 1/165 14/18639 0.0714285714285714 8.06883116883117 0.117087457210822 0.405224417129628 GO:0061578 K63-linked deubiquitinase activity 1/165 15/18639 0.0666666666666667 7.53090909090909 0.124909232757679 0.424904911432104 GO:0120283 protein serine/threonine kinase binding 1/165 15/18639 0.0666666666666667 7.53090909090909 0.124909232757679 0.424904911432104 GO:0004550 nucleoside diphosphate kinase activity 1/165 17/18639 0.0588235294117647 6.64491978609626 0.140346754751136 0.448629029820863 GO:0005092 GDP-dissociation inhibitor activity 1/165 17/18639 0.0588235294117647 6.64491978609626 0.140346754751136 0.448629029820863 GO:0008429 phosphatidylethanolamine binding 1/165 17/18639 0.0588235294117647 6.64491978609626 0.140346754751136 0.448629029820863 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/165 17/18639 0.0588235294117647 6.64491978609626 0.140346754751136 0.448629029820863 GO:0045236 CXCR chemokine receptor binding 1/165 17/18639 0.0588235294117647 6.64491978609626 0.140346754751136 0.448629029820863 GO:0046965 nuclear retinoid X receptor binding 1/165 17/18639 0.0588235294117647 6.64491978609626 0.140346754751136 0.448629029820863 GO:0048038 quinone binding 1/165 17/18639 0.0588235294117647 6.64491978609626 0.140346754751136 0.448629029820863 GO:0003725 double-stranded RNA binding 2/165 75/18639 0.0266666666666667 3.01236363636364 0.142614734955073 0.448629029820863 GO:0019209 kinase activator activity 3/165 148/18639 0.0202702702702703 2.28980343980344 0.143870991781119 0.448629029820863 GO:0019001 guanyl nucleotide binding 6/165 400/18639 0.015 1.69445454545455 0.144818996382597 0.448629029820863 GO:0032561 guanyl ribonucleotide binding 6/165 400/18639 0.015 1.69445454545455 0.144818996382597 0.448629029820863 GO:0032393 MHC class I receptor activity 1/165 18/18639 0.0555555555555556 6.27575757575758 0.147963701666938 0.448629029820863 GO:0000510 H3-H4 histone complex chaperone activity 3/165 151/18639 0.0198675496688742 2.24431065623119 0.150083300655049 0.448629029820863 GO:0140584 chromatin extrusion motor activity 3/165 151/18639 0.0198675496688742 2.24431065623119 0.150083300655049 0.448629029820863 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/165 151/18639 0.0198675496688742 2.24431065623119 0.150083300655049 0.448629029820863 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/165 151/18639 0.0198675496688742 2.24431065623119 0.150083300655049 0.448629029820863 GO:0015616 DNA translocase activity 3/165 152/18639 0.0197368421052632 2.22954545454545 0.152173163381448 0.448629029820863 GO:0140674 ATP-dependent histone chaperone activity 3/165 152/18639 0.0197368421052632 2.22954545454545 0.152173163381448 0.448629029820863 GO:0061775 cohesin loader activity 3/165 153/18639 0.0196078431372549 2.21497326203209 0.154272333478675 0.451473446503769 GO:0097001 ceramide binding 1/165 19/18639 0.0526315789473684 5.94545454545455 0.155513564146126 0.451783930877066 GO:0004386 helicase activity 3/165 155/18639 0.0193548387096774 2.18639296187683 0.15849802280244 0.457117486053414 GO:0000339 RNA cap binding 1/165 20/18639 0.05 5.64818181818182 0.162996929447731 0.463376985144263 GO:0016505 peptidase activator activity involved in apoptotic process 1/165 20/18639 0.05 5.64818181818182 0.162996929447731 0.463376985144263 GO:0140658 ATP-dependent chromatin remodeler activity 3/165 158/18639 0.0189873417721519 2.14487917146145 0.164902786027588 0.464716810739113 GO:0003689 DNA clamp loader activity 3/165 160/18639 0.01875 2.11806818181818 0.169215119200541 0.464716810739113 GO:0035613 RNA stem-loop binding 1/165 21/18639 0.0476190476190476 5.37922077922078 0.170414379721168 0.464716810739113 GO:0036122 BMP binding 1/165 21/18639 0.0476190476190476 5.37922077922078 0.170414379721168 0.464716810739113 GO:0072542 protein phosphatase activator activity 1/165 21/18639 0.0476190476190476 5.37922077922078 0.170414379721168 0.464716810739113 GO:0004860 protein kinase inhibitor activity 2/165 84/18639 0.0238095238095238 2.68961038961039 0.170474005949524 0.464716810739113 GO:0061133 endopeptidase activator activity 1/165 22/18639 0.0454545454545455 5.13471074380165 0.177766492050419 0.478505353119238 GO:0140713 histone chaperone activity 3/165 164/18639 0.0182926829268293 2.06640798226164 0.177936663973988 0.478505353119238 GO:0140104 molecular carrier activity 4/165 249/18639 0.0160642570281124 1.81467688937568 0.179709832226542 0.480030290108481 GO:0005212 structural constituent of eye lens 1/165 23/18639 0.0434782608695652 4.91146245059288 0.185053838497843 0.487428283355059 GO:0099186 structural constituent of postsynapse 1/165 23/18639 0.0434782608695652 4.91146245059288 0.185053838497843 0.487428283355059 GO:0003727 single-stranded RNA binding 2/165 89/18639 0.0224719101123595 2.53850868232891 0.18631936040386 0.487428283355059 GO:0019210 kinase inhibitor activity 2/165 90/18639 0.0222222222222222 2.51030303030303 0.189513695994606 0.487428283355059 GO:0019887 protein kinase regulator activity 4/165 255/18639 0.0156862745098039 1.77197860962567 0.190329429611771 0.487428283355059 GO:0005540 hyaluronic acid binding 1/165 24/18639 0.0416666666666667 4.70681818181818 0.192276986147599 0.487428283355059 GO:0050431 transforming growth factor beta binding 1/165 24/18639 0.0416666666666667 4.70681818181818 0.192276986147599 0.487428283355059 GO:0070840 dynein complex binding 1/165 24/18639 0.0416666666666667 4.70681818181818 0.192276986147599 0.487428283355059 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 5/165 349/18639 0.0143266475644699 1.61839020578276 0.197772203054991 0.489973616451763 GO:0008139 nuclear localization sequence binding 1/165 25/18639 0.04 4.51854545454546 0.199436497148708 0.489973616451763 GO:0019211 phosphatase activator activity 1/165 25/18639 0.04 4.51854545454546 0.199436497148708 0.489973616451763 GO:0042974 nuclear retinoic acid receptor binding 1/165 25/18639 0.04 4.51854545454546 0.199436497148708 0.489973616451763 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/165 25/18639 0.04 4.51854545454546 0.199436497148708 0.489973616451763 GO:0005112 Notch binding 1/165 26/18639 0.0384615384615385 4.34475524475525 0.206532928757737 0.495181359310718 GO:0008143 poly(A) binding 1/165 26/18639 0.0384615384615385 4.34475524475525 0.206532928757737 0.495181359310718 GO:0050681 nuclear androgen receptor binding 1/165 26/18639 0.0384615384615385 4.34475524475525 0.206532928757737 0.495181359310718 GO:0050750 low-density lipoprotein particle receptor binding 1/165 26/18639 0.0384615384615385 4.34475524475525 0.206532928757737 0.495181359310718 GO:0001671 ATPase activator activity 1/165 27/18639 0.037037037037037 4.18383838383838 0.213566833381117 0.502956211157896 GO:0023026 MHC class II protein complex binding 1/165 27/18639 0.037037037037037 4.18383838383838 0.213566833381117 0.502956211157896 GO:0035255 ionotropic glutamate receptor binding 1/165 27/18639 0.037037037037037 4.18383838383838 0.213566833381117 0.502956211157896 GO:0046625 sphingolipid binding 1/165 28/18639 0.0357142857142857 4.03441558441558 0.2205387586171 0.510316429823289 GO:0046875 ephrin receptor binding 1/165 28/18639 0.0357142857142857 4.03441558441558 0.2205387586171 0.510316429823289 GO:0051019 mitogen-activated protein kinase binding 1/165 28/18639 0.0357142857142857 4.03441558441558 0.2205387586171 0.510316429823289 GO:0035250 UDP-galactosyltransferase activity 1/165 29/18639 0.0344827586206897 3.89529780564263 0.227449247297352 0.523264742337261 GO:0140597 protein carrier chaperone 3/165 188/18639 0.0159574468085106 1.80261121856867 0.232513698068848 0.531841677191962 GO:0098918 structural constituent of synapse 1/165 30/18639 0.0333333333333333 3.76545454545455 0.234298837528192 0.532862499064118 GO:0017147 Wnt-protein binding 1/165 31/18639 0.032258064516129 3.64398826979472 0.241088062731473 0.542107621283199 GO:0070325 lipoprotein particle receptor binding 1/165 31/18639 0.032258064516129 3.64398826979472 0.241088062731473 0.542107621283199 GO:0005525 GTP binding 5/165 378/18639 0.0132275132275132 1.49422799422799 0.244068205421461 0.54492456226892 GO:0008378 galactosyltransferase activity 1/165 32/18639 0.03125 3.53011363636364 0.247817451685112 0.54492456226892 GO:0051059 NF-kappaB binding 1/165 32/18639 0.03125 3.53011363636364 0.247817451685112 0.54492456226892 GO:0070717 poly-purine tract binding 1/165 32/18639 0.03125 3.53011363636364 0.247817451685112 0.54492456226892 GO:0140311 protein sequestering activity 1/165 33/18639 0.0303030303030303 3.42314049586777 0.254487528563274 0.553009738676176 GO:0140416 transcription regulator inhibitor activity 1/165 33/18639 0.0303030303030303 3.42314049586777 0.254487528563274 0.553009738676176 GO:0015631 tubulin binding 5/165 385/18639 0.012987012987013 1.46706021251476 0.25566279375984 0.553009738676176 GO:0030332 cyclin binding 1/165 34/18639 0.0294117647058824 3.32245989304813 0.261098812976208 0.558695309486725 GO:0051427 hormone receptor binding 1/165 34/18639 0.0294117647058824 3.32245989304813 0.261098812976208 0.558695309486725 GO:0140297 DNA-binding transcription factor binding 6/165 488/18639 0.0122950819672131 1.38889716840537 0.264607009360407 0.563174276606642 GO:0000175 3'-5'-RNA exonuclease activity 1/165 35/18639 0.0285714285714286 3.22753246753247 0.267651820009743 0.563626583935862 GO:0043015 gamma-tubulin binding 1/165 35/18639 0.0285714285714286 3.22753246753247 0.267651820009743 0.563626583935862 GO:0035401 histone H3Y41 kinase activity 2/165 115/18639 0.0173913043478261 1.96458498023715 0.270908952304381 0.564511848257297 GO:0140801 histone H2AXY142 kinase activity 2/165 115/18639 0.0173913043478261 1.96458498023715 0.270908952304381 0.564511848257297 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/165 36/18639 0.0277777777777778 3.13787878787879 0.274147060264441 0.56828401033983 GO:1990782 protein tyrosine kinase binding 2/165 117/18639 0.0170940170940171 1.93100233100233 0.277469607558245 0.571062858685155 GO:0023023 MHC protein complex binding 1/165 37/18639 0.027027027027027 3.05307125307125 0.280585039894413 0.571062858685155 GO:0043394 proteoglycan binding 1/165 37/18639 0.027027027027027 3.05307125307125 0.280585039894413 0.571062858685155 GO:0008094 ATP-dependent activity, acting on DNA 3/165 210/18639 0.0142857142857143 1.61376623376623 0.284821613571845 0.571062858685155 GO:0005501 retinoid binding 1/165 38/18639 0.0263157894736842 2.97272727272727 0.286966260645806 0.571062858685155 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/165 38/18639 0.0263157894736842 2.97272727272727 0.286966260645806 0.571062858685155 GO:0019840 isoprenoid binding 1/165 38/18639 0.0263157894736842 2.97272727272727 0.286966260645806 0.571062858685155 GO:0042162 telomeric DNA binding 1/165 38/18639 0.0263157894736842 2.97272727272727 0.286966260645806 0.571062858685155 GO:0004175 endopeptidase activity 5/165 405/18639 0.0123456790123457 1.39461279461279 0.289479391804313 0.573197999692122 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/165 39/18639 0.0256410256410256 2.8965034965035 0.293291219894957 0.577870819396994 GO:0004532 RNA exonuclease activity 1/165 40/18639 0.025 2.82409090909091 0.299560410686211 0.581585577820059 GO:0061791 GTPase motor activity 1/165 40/18639 0.025 2.82409090909091 0.299560410686211 0.581585577820059 GO:1990606 membrane scission GTPase motor activity 1/165 40/18639 0.025 2.82409090909091 0.299560410686211 0.581585577820059 GO:0001530 lipopolysaccharide binding 1/165 41/18639 0.024390243902439 2.75521064301552 0.305774321769429 0.585777280418458 GO:0042169 SH2 domain binding 1/165 41/18639 0.024390243902439 2.75521064301552 0.305774321769429 0.585777280418458 GO:0004520 DNA endonuclease activity 1/165 42/18639 0.0238095238095238 2.68961038961039 0.311933437637159 0.585777280418458 GO:0019894 kinesin binding 1/165 42/18639 0.0238095238095238 2.68961038961039 0.311933437637159 0.585777280418458 GO:0051879 Hsp90 protein binding 1/165 42/18639 0.0238095238095238 2.68961038961039 0.311933437637159 0.585777280418458 GO:0035591 signaling adaptor activity 2/165 129/18639 0.0155038759689922 1.75137420718816 0.316698714257076 0.585777280418458 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/165 43/18639 0.0232558139534884 2.62706131078224 0.318038238561495 0.585777280418458 GO:0008200 ion channel inhibitor activity 1/165 43/18639 0.0232558139534884 2.62706131078224 0.318038238561495 0.585777280418458 GO:0048156 tau protein binding 1/165 43/18639 0.0232558139534884 2.62706131078224 0.318038238561495 0.585777280418458 GO:0016248 channel inhibitor activity 1/165 44/18639 0.0227272727272727 2.56735537190083 0.324089200630615 0.585777280418458 GO:0019205 nucleobase-containing compound kinase activity 1/165 44/18639 0.0227272727272727 2.56735537190083 0.324089200630615 0.585777280418458 GO:0030547 signaling receptor inhibitor activity 1/165 44/18639 0.0227272727272727 2.56735537190083 0.324089200630615 0.585777280418458 GO:0043014 alpha-tubulin binding 1/165 44/18639 0.0227272727272727 2.56735537190083 0.324089200630615 0.585777280418458 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/165 45/18639 0.0222222222222222 2.51030303030303 0.330086795785008 0.585777280418458 GO:0042605 peptide antigen binding 1/165 45/18639 0.0222222222222222 2.51030303030303 0.330086795785008 0.585777280418458 GO:0141110 transporter inhibitor activity 1/165 45/18639 0.0222222222222222 2.51030303030303 0.330086795785008 0.585777280418458 GO:0003924 GTPase activity 4/165 331/18639 0.0120845921450151 1.36511947267234 0.336885806638417 0.585777280418458 GO:0005504 fatty acid binding 1/165 47/18639 0.0212765957446809 2.40348162475822 0.341923752588299 0.585777280418458 GO:0016922 nuclear receptor binding 2/165 137/18639 0.0145985401459854 1.64910418049104 0.34259839897793 0.585777280418458 GO:0140097 catalytic activity, acting on DNA 4/165 336/18639 0.0119047619047619 1.34480519480519 0.346930760172487 0.585777280418458 GO:0030295 protein kinase activator activity 2/165 139/18639 0.0143884892086331 1.62537606278613 0.349027770935849 0.585777280418458 GO:0004713 protein tyrosine kinase activity 2/165 140/18639 0.0142857142857143 1.61376623376623 0.352234692469087 0.585777280418458 GO:0005004 GPI-linked ephrin receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0005008 hepatocyte growth factor receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0005009 insulin receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0005011 macrophage colony-stimulating factor receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0005020 stem cell factor receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0008288 boss receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0036332 placental growth factor receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0038062 protein tyrosine kinase collagen receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0060175 brain-derived neurotrophic factor receptor activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0060590 ATPase regulator activity 1/165 49/18639 0.0204081632653061 2.30538033395176 0.353552802898508 0.585777280418458 GO:0020037 heme binding 2/165 142/18639 0.0140845070422535 1.5910371318822 0.358632212935766 0.585777280418458 GO:0005006 epidermal growth factor receptor activity 1/165 50/18639 0.02 2.25927272727273 0.359290499914202 0.585777280418458 GO:0005007 fibroblast growth factor receptor activity 1/165 50/18639 0.02 2.25927272727273 0.359290499914202 0.585777280418458 GO:0005017 platelet-derived growth factor receptor activity 1/165 50/18639 0.02 2.25927272727273 0.359290499914202 0.585777280418458 GO:0005019 platelet-derived growth factor beta-receptor activity 1/165 50/18639 0.02 2.25927272727273 0.359290499914202 0.585777280418458 GO:0005010 insulin-like growth factor receptor activity 1/165 51/18639 0.0196078431372549 2.21497326203209 0.364977576546304 0.585777280418458 GO:0005021 vascular endothelial growth factor receptor activity 1/165 51/18639 0.0196078431372549 2.21497326203209 0.364977576546304 0.585777280418458 GO:0005030 neurotrophin receptor activity 1/165 51/18639 0.0196078431372549 2.21497326203209 0.364977576546304 0.585777280418458 GO:0005048 signal sequence binding 1/165 51/18639 0.0196078431372549 2.21497326203209 0.364977576546304 0.585777280418458 GO:0019955 cytokine binding 2/165 144/18639 0.0138888888888889 1.56893939393939 0.365006948602456 0.585777280418458 GO:0005080 protein kinase C binding 1/165 52/18639 0.0192307692307692 2.17237762237762 0.370614476689938 0.587169619089381 GO:0005003 ephrin receptor activity 1/165 53/18639 0.0188679245283019 2.13138936535163 0.376201640371337 0.587169619089381 GO:0005005 transmembrane-ephrin receptor activity 1/165 53/18639 0.0188679245283019 2.13138936535163 0.376201640371337 0.587169619089381 GO:0016860 intramolecular oxidoreductase activity 1/165 53/18639 0.0188679245283019 2.13138936535163 0.376201640371337 0.587169619089381 GO:0038064 collagen receptor activity 1/165 53/18639 0.0188679245283019 2.13138936535163 0.376201640371337 0.587169619089381 GO:0051018 protein kinase A binding 1/165 53/18639 0.0188679245283019 2.13138936535163 0.376201640371337 0.587169619089381 GO:0140296 general transcription initiation factor binding 1/165 53/18639 0.0188679245283019 2.13138936535163 0.376201640371337 0.587169619089381 GO:0042277 peptide binding 3/165 249/18639 0.0120481927710843 1.36100766703176 0.379019114356003 0.588884970949543 GO:0015485 cholesterol binding 1/165 54/18639 0.0185185185185185 2.09191919191919 0.381739503781362 0.588884970949543 GO:0140463 chromatin-protein adaptor activity 1/165 54/18639 0.0185185185185185 2.09191919191919 0.381739503781362 0.588884970949543 GO:0045182 translation regulator activity 4/165 356/18639 0.0112359550561798 1.26925434116445 0.387111126941849 0.592757472018743 GO:0140313 molecular sequestering activity 1/165 55/18639 0.0181818181818182 2.05388429752066 0.387228499308727 0.592757472018743 GO:0046906 tetrapyrrole binding 2/165 152/18639 0.0131578947368421 1.48636363636364 0.390255111770559 0.59510166469227 GO:0003713 transcription coactivator activity 3/165 256/18639 0.01171875 1.32379261363636 0.395771390287758 0.600025304101546 GO:0005506 iron ion binding 2/165 154/18639 0.012987012987013 1.46706021251476 0.396499133112328 0.600025304101546 GO:0140375 immune receptor activity 2/165 156/18639 0.0128205128205128 1.44825174825175 0.402713973058534 0.605870963635952 GO:0008408 3'-5' exonuclease activity 1/165 58/18639 0.0172413793103448 1.94764890282132 0.403406546139516 0.605870963635952 GO:0004879 nuclear receptor activity 1/165 59/18639 0.0169491525423729 1.91463790446841 0.408704319127352 0.609229659223543 GO:0031593 polyubiquitin modification-dependent protein binding 1/165 59/18639 0.0169491525423729 1.91463790446841 0.408704319127352 0.609229659223543 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/165 60/18639 0.0166666666666667 1.88272727272727 0.413955330286877 0.610200820200656 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/165 60/18639 0.0166666666666667 1.88272727272727 0.413955330286877 0.610200820200656 GO:0098531 ligand-modulated transcription factor activity 1/165 60/18639 0.0166666666666667 1.88272727272727 0.413955330286877 0.610200820200656 GO:0004536 DNA nuclease activity 1/165 64/18639 0.015625 1.76505681818182 0.434499908320203 0.638121636573582 GO:0016874 ligase activity 2/165 167/18639 0.0119760479041916 1.35285792052259 0.436335225321139 0.638461101756667 GO:0008017 microtubule binding 3/165 276/18639 0.0108695652173913 1.22786561264822 0.442906705714311 0.645702816389362 GO:0140098 catalytic activity, acting on RNA 4/165 387/18639 0.0103359173126615 1.16758280479211 0.448660128703199 0.645761597869996 GO:0016500 protein-hormone receptor activity 1/165 67/18639 0.0149253731343284 1.68602442333786 0.449437091984897 0.645761597869996 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/165 67/18639 0.0149253731343284 1.68602442333786 0.449437091984897 0.645761597869996 GO:0050840 extracellular matrix binding 1/165 67/18639 0.0149253731343284 1.68602442333786 0.449437091984897 0.645761597869996 GO:0030145 manganese ion binding 1/165 68/18639 0.0147058823529412 1.66122994652406 0.454328481163364 0.645795483939353 GO:0032934 sterol binding 1/165 68/18639 0.0147058823529412 1.66122994652406 0.454328481163364 0.645795483939353 GO:1990841 promoter-specific chromatin binding 1/165 68/18639 0.0147058823529412 1.66122994652406 0.454328481163364 0.645795483939353 GO:0003823 antigen binding 2/165 174/18639 0.0114942528735632 1.29843260188088 0.457196813859579 0.64755990005734 GO:0002039 p53 binding 1/165 69/18639 0.0144927536231884 1.63715415019763 0.459176674615954 0.64805785991897 GO:0097110 scaffold protein binding 1/165 70/18639 0.0142857142857143 1.61376623376623 0.463982051497395 0.652525994685383 GO:0140299 molecular sensor activity 1/165 71/18639 0.0140845070422535 1.5910371318822 0.468744987654589 0.656903186924389 GO:0043539 protein serine/threonine kinase activator activity 1/165 73/18639 0.0136986301369863 1.54744707347447 0.478145024816536 0.667725332901689 GO:0003678 DNA helicase activity 1/165 74/18639 0.0135135135135135 1.52653562653563 0.482782861232849 0.668692659951372 GO:0003684 damaged DNA binding 1/165 74/18639 0.0135135135135135 1.52653562653563 0.482782861232849 0.668692659951372 GO:0061135 endopeptidase regulator activity 2/165 184/18639 0.0108695652173913 1.22786561264822 0.486216358256761 0.668692659951372 GO:0019003 GDP binding 1/165 75/18639 0.0133333333333333 1.50618181818182 0.48737972780417 0.668692659951372 GO:0044183 protein folding chaperone 1/165 75/18639 0.0133333333333333 1.50618181818182 0.48737972780417 0.668692659951372 GO:0051536 iron-sulfur cluster binding 1/165 76/18639 0.0131578947368421 1.48636363636364 0.491935984263571 0.668692659951372 GO:0051540 metal cluster binding 1/165 77/18639 0.012987012987013 1.46706021251476 0.496451987204718 0.668692659951372 GO:0019199 transmembrane receptor protein kinase activity 1/165 78/18639 0.0128205128205128 1.44825174825175 0.500928090109104 0.668692659951372 GO:0016835 carbon-oxygen lyase activity 1/165 79/18639 0.0126582278481013 1.42991944764097 0.505364643373045 0.668692659951372 GO:0033293 monocarboxylic acid binding 1/165 79/18639 0.0126582278481013 1.42991944764097 0.505364643373045 0.668692659951372 GO:0000049 tRNA binding 1/165 80/18639 0.0125 1.41204545454545 0.509761994334437 0.668692659951372 GO:0048306 calcium-dependent protein binding 1/165 80/18639 0.0125 1.41204545454545 0.509761994334437 0.668692659951372 GO:0030971 receptor tyrosine kinase binding 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0033192 calmodulin-dependent protein phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0140791 histone H2AXS140 phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/165 81/18639 0.0123456790123457 1.39461279461279 0.514120487299296 0.668692659951372 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/165 82/18639 0.0121951219512195 1.37760532150776 0.518440463568055 0.668950032352839 GO:0033549 MAP kinase phosphatase activity 1/165 82/18639 0.0121951219512195 1.37760532150776 0.518440463568055 0.668950032352839 GO:0001540 amyloid-beta binding 1/165 83/18639 0.0120481927710843 1.36100766703176 0.52272226146164 0.668950032352839 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/165 83/18639 0.0120481927710843 1.36100766703176 0.52272226146164 0.668950032352839 GO:0005254 chloride channel activity 1/165 83/18639 0.0120481927710843 1.36100766703176 0.52272226146164 0.668950032352839 GO:0004527 exonuclease activity 1/165 84/18639 0.0119047619047619 1.34480519480519 0.526966216347328 0.670072057847402 GO:0017018 myosin phosphatase activity 1/165 84/18639 0.0119047619047619 1.34480519480519 0.526966216347328 0.670072057847402 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/165 89/18639 0.0112359550561798 1.26925434116445 0.5476298799669 0.691699224612492 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/165 89/18639 0.0112359550561798 1.26925434116445 0.5476298799669 0.691699224612492 GO:0005516 calmodulin binding 2/165 207/18639 0.00966183574879227 1.09143610013175 0.549188329089315 0.691699224612492 GO:0140793 histone H2AXY142 phosphatase activity 1/165 90/18639 0.0111111111111111 1.25515151515152 0.551653657314904 0.692612478269185 GO:0004518 nuclease activity 2/165 209/18639 0.00956937799043062 1.08099173553719 0.554404446939584 0.693877263779731 GO:0043178 alcohol binding 1/165 92/18639 0.0108695652173913 1.22786561264822 0.559594796611036 0.698177834016276 GO:0051219 phosphoprotein binding 1/165 93/18639 0.010752688172043 1.21466275659824 0.563512781113067 0.700869021509377 GO:0016410 N-acyltransferase activity 1/165 94/18639 0.0106382978723404 1.20174081237911 0.567396119359392 0.703500484439371 GO:0004867 serine-type endopeptidase inhibitor activity 1/165 95/18639 0.0105263157894737 1.18909090909091 0.571245115870888 0.706073155641657 GO:0004896 cytokine receptor activity 1/165 96/18639 0.0104166666666667 1.17670454545455 0.575060072508146 0.708587953121493 GO:0004725 protein tyrosine phosphatase activity 1/165 98/18639 0.0102040816326531 1.15269016697588 0.582589060439252 0.715649524860563 GO:0043130 ubiquitin binding 1/165 100/18639 0.01 1.12963636363636 0.589985445704422 0.7225052535088 GO:0004722 protein serine/threonine phosphatase activity 1/165 103/18639 0.00970873786407767 1.09673433362754 0.600836460699064 0.731293306905895 GO:0005253 monoatomic anion channel activity 1/165 103/18639 0.00970873786407767 1.09673433362754 0.600836460699064 0.731293306905895 GO:0000149 SNARE binding 1/165 106/18639 0.00943396226415094 1.06569468267581 0.611401998670855 0.73962916556535 GO:0008013 beta-catenin binding 1/165 106/18639 0.00943396226415094 1.06569468267581 0.611401998670855 0.73962916556535 GO:0004843 cysteine-type deubiquitinase activity 1/165 108/18639 0.00925925925925926 1.0459595959596 0.618290787241419 0.74344330308787 GO:0005496 steroid binding 1/165 108/18639 0.00925925925925926 1.0459595959596 0.618290787241419 0.74344330308787 GO:0005200 structural constituent of cytoskeleton 1/165 112/18639 0.00892857142857143 1.0086038961039 0.631706313289244 0.757286484003371 GO:0101005 deubiquitinase activity 1/165 115/18639 0.00869565217391304 0.982292490118577 0.641459444604485 0.764693707439675 GO:0003712 transcription coregulator activity 4/165 495/18639 0.00808080808080808 0.912837465564738 0.641727885137817 0.764693707439675 GO:0033218 amide binding 2/165 247/18639 0.00809716599190283 0.914685314685315 0.645369113241122 0.766737036029751 GO:0032182 ubiquitin-like protein binding 1/165 120/18639 0.00833333333333333 0.941363636363636 0.657147415970376 0.775104592690927 GO:0003697 single-stranded DNA binding 1/165 121/18639 0.00826446280991736 0.9335837716003 0.660202153070915 0.775104592690927 GO:0004540 RNA nuclease activity 1/165 121/18639 0.00826446280991736 0.9335837716003 0.660202153070915 0.775104592690927 GO:0015108 chloride transmembrane transporter activity 1/165 121/18639 0.00826446280991736 0.9335837716003 0.660202153070915 0.775104592690927 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/165 122/18639 0.00819672131147541 0.925931445603577 0.663229836662194 0.776369044092803 GO:0004519 endonuclease activity 1/165 127/18639 0.0078740157480315 0.889477451682176 0.677970714492129 0.787717210162431 GO:0019783 ubiquitin-like protein peptidase activity 1/165 127/18639 0.0078740157480315 0.889477451682176 0.677970714492129 0.787717210162431 GO:0031490 chromatin DNA binding 1/165 128/18639 0.0078125 0.882528409090909 0.680841005768533 0.787717210162431 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/165 128/18639 0.0078125 0.882528409090909 0.680841005768533 0.787717210162431 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/165 130/18639 0.00769230769230769 0.868951048951049 0.686505523383988 0.791968690744427 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/165 268/18639 0.00746268656716418 0.843012211668928 0.689051252747977 0.792608088421083 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/165 132/18639 0.00757575757575758 0.855785123966942 0.692070104197155 0.793786459569071 GO:0005096 GTPase activator activity 2/165 271/18639 0.00738007380073801 0.833679973163368 0.694919601946194 0.794764372340762 GO:0016791 phosphatase activity 2/165 273/18639 0.00732600732600733 0.827572427572428 0.698781166446603 0.796890843111026 GO:0140789 histone phosphatase activity 1/165 136/18639 0.00735294117647059 0.830614973262032 0.702906435197436 0.799305032024513 GO:0001217 DNA-binding transcription repressor activity 2/165 278/18639 0.00719424460431655 0.812688031393067 0.708259247007435 0.803097379797604 GO:0016887 ATP hydrolysis activity 3/165 417/18639 0.00719424460431655 0.812688031393067 0.717636244944691 0.811418254227236 GO:0019903 protein phosphatase binding 1/165 144/18639 0.00694444444444444 0.784469696969697 0.723454951767162 0.815680087261559 GO:0008194 UDP-glycosyltransferase activity 1/165 145/18639 0.00689655172413793 0.779059561128527 0.725922101426985 0.816149707254068 GO:0008509 monoatomic anion transmembrane transporter activity 1/165 149/18639 0.00671140939597315 0.758145210494204 0.735573839557764 0.824671515898564 GO:0003774 cytoskeletal motor activity 1/165 153/18639 0.0065359477124183 0.738324420677362 0.744887676355777 0.832767683116852 GO:0099106 ion channel regulator activity 1/165 160/18639 0.00625 0.706022727272727 0.760408957989763 0.845387786171272 GO:0005216 monoatomic ion channel activity 3/165 448/18639 0.00669642857142857 0.756452922077922 0.761705293192937 0.845387786171272 GO:0004866 endopeptidase inhibitor activity 1/165 161/18639 0.0062111801242236 0.701637492941841 0.762548279486147 0.845387786171272 GO:0015103 inorganic anion transmembrane transporter activity 1/165 165/18639 0.00606060606060606 0.684628099173554 0.770917359409771 0.852291969569691 GO:0016247 channel regulator activity 1/165 168/18639 0.00595238095238095 0.672402597402597 0.777001161486777 0.856267436300065 GO:0030414 peptidase inhibitor activity 1/165 169/18639 0.00591715976331361 0.668423883808499 0.778993192689997 0.856267436300065 GO:0141108 transporter regulator activity 1/165 170/18639 0.00588235294117647 0.664491978609626 0.780967536122924 0.856267436300065 GO:0140030 modification-dependent protein binding 1/165 173/18639 0.00578034682080925 0.652968996321597 0.786785994016953 0.860276993458097 GO:0004721 phosphoprotein phosphatase activity 1/165 175/18639 0.00571428571428571 0.645506493506493 0.790579352737378 0.862056390108154 GO:0005319 lipid transporter activity 1/165 178/18639 0.00561797752808989 0.634627170582227 0.79614397190194 0.864466068245761 GO:0016853 isomerase activity 1/165 180/18639 0.00555555555555556 0.627575757575758 0.799771817760611 0.864466068245761 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/165 484/18639 0.00619834710743802 0.700187828700225 0.80576248710309 0.864466068245761 GO:0005261 monoatomic cation channel activity 2/165 341/18639 0.00586510263929619 0.662543321780858 0.807677191033443 0.864466068245761 GO:0030695 GTPase regulator activity 3/165 489/18639 0.00613496932515337 0.693028443948689 0.811310267256481 0.864466068245761 GO:0008234 cysteine-type peptidase activity 1/165 187/18639 0.0053475935828877 0.604083616917842 0.81197124002659 0.864466068245761 GO:0031406 carboxylic acid binding 1/165 187/18639 0.0053475935828877 0.604083616917842 0.81197124002659 0.864466068245761 GO:0060589 nucleoside-triphosphatase regulator activity 3/165 490/18639 0.00612244897959184 0.691614100185529 0.812403752716391 0.864466068245761 GO:0001216 DNA-binding transcription activator activity 3/165 491/18639 0.00610997963340122 0.69020551749676 0.813491919098455 0.864466068245761 GO:0043177 organic acid binding 1/165 189/18639 0.00529100529100529 0.597691197691198 0.81531904678049 0.864466068245761 GO:0019902 phosphatase binding 1/165 190/18639 0.00526315789473684 0.594545454545454 0.816970665061315 0.864466068245761 GO:0016755 aminoacyltransferase activity 3/165 496/18639 0.00604838709677419 0.68324780058651 0.818853537006663 0.864466068245761 GO:0141003 histone H2AX kinase activity 2/165 354/18639 0.00564971751412429 0.638212634822804 0.824023701390991 0.867289896900159 GO:0140996 histone H3 kinase activity 2/165 357/18639 0.00560224089635854 0.632849503437739 0.827615520099284 0.867289896900159 GO:0016758 hexosyltransferase activity 1/165 197/18639 0.0050761421319797 0.573419473927088 0.828128086637747 0.867289896900159 GO:0035173 histone kinase activity 2/165 360/18639 0.00555555555555556 0.627575757575758 0.831141669480382 0.867289896900159 GO:0016829 lyase activity 1/165 200/18639 0.005 0.564818181818182 0.832700379282393 0.867289896900159 GO:0042578 phosphoric ester hydrolase activity 2/165 363/18639 0.00550964187327824 0.622389181066867 0.834603091740606 0.867289896900159 GO:0051015 actin filament binding 1/165 209/18639 0.00478468899521531 0.540495867768595 0.84570437769518 0.87653734979865 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/165 229/18639 0.00436681222707424 0.493290988487495 0.871115718095082 0.89706407428058 GO:0000287 magnesium ion binding 1/165 230/18639 0.00434782608695652 0.491146245059288 0.872270846096946 0.89706407428058 GO:0005085 guanyl-nucleotide exchange factor activity 1/165 230/18639 0.00434782608695652 0.491146245059288 0.872270846096946 0.89706407428058 GO:0042393 histone binding 1/165 247/18639 0.00404858299595142 0.457342657342657 0.890405509997104 0.913354105615586 GO:0003779 actin binding 2/165 443/18639 0.00451467268623025 0.509993843628155 0.906204981944682 0.926500944229777 GO:0016757 glycosyltransferase activity 1/165 267/18639 0.00374531835205993 0.423084780388151 0.908489109127234 0.926500944229777 GO:0004842 ubiquitin-protein transferase activity 2/165 449/18639 0.0044543429844098 0.503178781129783 0.910205701492067 0.926500944229777 GO:0019787 ubiquitin-like protein transferase activity 2/165 479/18639 0.00417536534446764 0.471664452457772 0.927930217837025 0.942133231375347 GO:0005543 phospholipid binding 2/165 497/18639 0.00402414486921529 0.454582037680629 0.936930697936142 0.94885093582337 GO:0061630 ubiquitin protein ligase activity 1/165 353/18639 0.0028328611898017 0.320010301313417 0.95795295244588 0.967037837047742 GO:0106310 protein serine kinase activity 1/165 361/18639 0.00277008310249307 0.312918660287081 0.960894575133069 0.967037837047742 GO:0046982 protein heterodimerization activity 1/165 369/18639 0.002710027100271 0.306134515890613 0.963631561096338 0.967037837047742 GO:0061659 ubiquitin-like protein ligase activity 1/165 372/18639 0.00268817204301075 0.30366568914956 0.964608093738577 0.967037837047742 GO:0004674 protein serine/threonine kinase activity 1/165 433/18639 0.0023094688221709 0.260885996220869 0.979670544963103 0.979670544963103