category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	56/160	238/9376	13.7882352941176	CFD/RPL10/RPS4X/RPLP0/RPS2/RPL18A/RPL7A/RPL3/RPL12/RPL13A/JUN/RPL10A/RPL5/RPL6/RPS9/RPS18/RPS27/RPS5/RPL23A/RPL9/RPL37A/RPL15/RPS6/RPS3/RPS29/RPS7/RPL7/RPS23/RPL29/NFKBIA/RPS20/RPL13/RPL37/C1R/RPS13/RPL27A/STAT3/RPS17/RPS8/RPS14/RPL18/RPL31/RPL30/RPL8/RPL24/RPL17/RPL36/RPL4/RPS11/RPSA/RPL14/RPS16/RPS25/C1S/RPL35A/PRKCB	26.3298216007727
Genetic Information Processing	Translation	hsa03010	Ribosome	51/160	222/9376	13.4621621621622	RPL10/RPS4X/RPLP0/RPS2/RPL18A/RPL7A/RPL3/RPL12/RPL13A/RPL10A/RPL5/RPL6/RPS9/RPS18/RPS27/RPS5/RPL23A/RPL9/RACK1/RPL37A/RPL15/RPS6/RPS3/RPS29/RPS7/RPL7/RPS23/RPL29/RPS20/RPL13/RPL37/RPS13/RPL27A/RPS17/RPS8/RPS14/RPL18/RPL31/RPL30/RPL8/RPL24/RPL17/RPL36/RPL4/RPS11/RPSA/RPL14/RPS16/RPS25/MRPL18/RPL35A	24.759326553247
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	8/160	89/9376	5.26741573033708	COL6A1/COL6A3/SPP1/COL6A2/COL1A1/COL1A2/TNXB/LAMB1	5.3296247333198
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	13/160	233/9376	3.26952789699571	FBLN1/VCAN/COL6A1/COL3A1/VIM/COL6A3/ACTG1/COL6A2/COL1A1/COL1A2/FBLN2/TPM2/SPTBN1	4.62214454324024
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	12/160	203/9376	3.464039408867	JUN/COL6A1/COL6A3/SPP1/ACTG1/COL6A2/COL1A1/COL1A2/TNXB/PAK3/LAMB1/PRKCB	4.67642924903582
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	8/160	103/9376	4.55145631067961	COL6A1/COL3A1/COL6A3/COL6A2/COL1A1/COL1A2/COL15A1/COL23A1	4.77517569495242
NA	NA	hsa04518	Integrin signaling	9/160	154/9376	3.42467532467532	COL6A1/COL6A3/SPP1/ACTG1/COL6A2/COL1A1/COL1A2/TNXB/LAMB1	3.99738327214544
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	7/160	101/9376	4.06138613861386	JUN/COL3A1/COL1A1/COL1A2/STAT3/STAT5A/PRKCB	4.07564393930168
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	7/160	103/9376	3.98252427184466	COL3A1/COL1A1/COL1A2/ARG2/LAMB1/SERPINB9/PRKCB	4.01020769133238
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	7/160	105/9376	3.90666666666667	CCL4L2/NFKBIA/CXCL12/TNFAIP3/CCL4/CARD10/PRKCB	3.94639893904618
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	9/160	193/9376	2.73264248704663	CCL4L2/NFKBIA/CXCL12/CCL3L1/STAT3/PIK3R6/CCL4/GNG4/PRKCB	3.20456967478322
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	9/160	205/9376	2.57268292682927	COL3A1/MT-CO3/MT-ATP8/COL1A1/COL1A2/SLC25A6/MT-ND4L/MT-CYB/PRKCB	2.99974371699966
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	13/160	362/9376	2.10441988950276	COL6A1/RPS6/CSH1/COL6A3/SPP1/COL6A2/COL1A1/COL1A2/PIK3R6/TNXB/LAMB1/FGF10/GNG4	2.82360618244082
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/160	78/9376	3.75641025641026	EEF1A1/JUN/NFKBIA/HLA-DRB5/PRKCB	3.22085211078377
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	6/160	109/9376	3.2256880733945	JUN/CCL4L2/SPP1/NFKBIA/CCL3L1/CCL4	3.07951527443627
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	4/160	54/9376	4.34074074074074	CGA/HLA-DRB5/TG/HLA-B	3.24384056519547
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/160	56/9376	4.18571428571429	EEF1A1/EEF1G/NFKBIA/CLK1	3.15041144732739
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	9/160	227/9376	2.32334801762115	CCL4L2/NFKBIA/CXCL12/CCL3L1/STAT3/CCL4/HLA-B/GNG4/PRKCB	2.65934438704228
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	9/160	227/9376	2.32334801762115	JUN/MT-CO3/MT-ATP8/NFKBIA/SOD2/SLC25A6/MT-ND4L/MT-CYB/CYP1B1	2.65934438704228
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	8/160	196/9376	2.39183673469388	JUN/NFKBIA/MAP1LC3B/STAT3/PIK3R6/UBC/HLA-B/GNG4	2.59459386108089
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/160	130/9376	2.70461538461538	JUN/COL3A1/NFKBIA/COL1A1/COL1A2/GNG4	2.57866859926653
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	5/160	99/9376	2.95959595959596	CFD/C1R/KRT19/HLA-DRB5/C1S	2.5825857526289
Human Diseases	Infectious disease: viral	hsa05162	Measles	6/160	136/9376	2.58529411764706	JUN/RACK1/NFKBIA/STAT3/TNFAIP3/STAT5A	2.45367881482218
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/160	109/9376	2.68807339449541	JUN/NFKBIA/HLA-DRB5/STAT3/STAT5A	2.33565874071011
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	5/160	110/9376	2.66363636363636	RPS6/LDHA/TIMP1/STAT3/PRKCB	2.31250667878912
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	5/160	112/9376	2.61607142857143	NFKBIA/HLA-DRB5/STAT3/PIK3R6/LAMB1	2.26696433074693
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	6/160	154/9376	2.28311688311688	JUN/ACTG1/EEF2/PIK3R6/MYL6/PRKCB	2.11538011402234
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	3/160	52/9376	3.38076923076923	ABCA1/MYLIP/APOE	2.26825688048084
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	4/160	86/9376	2.72558139534884	JUN/PAK3/STAT5A/PRKCB	2.11812318877469
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/160	204/9376	2.01078431372549	DDX5/RPS6/ACTG1/COL1A1/COL1A2/STAT3/PRKCB	1.92316236119319
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	6/160	163/9376	2.15705521472393	JUN/DDX3X/NFKBIA/STAT3/STAT5A/PRKCB	1.96345859370478
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	7/160	205/9376	2.0009756097561	JUN/VIM/NFKBIA/HLA-DRB5/STAT3/TNFAIP3/HLA-B	1.90926616230872
Organismal Systems	Immune system	hsa04611	Platelet activation	5/160	126/9376	2.32539682539683	COL3A1/ACTG1/COL1A1/COL1A2/PIK3R6	1.97348908486889
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	6/160	168/9376	2.09285714285714	SQSTM1/STAT3/SLC25A6/TNFAIP3/FTL/STAT5A	1.88325781009616
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	4/160	91/9376	2.57582417582418	JUN/NFKBIA/IFITM1/PRKCB	1.99026954553622
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	4/160	93/9376	2.52043010752688	JUN/NFKBIA/HLA-DRB5/STAT5A	1.9415034045488
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	7/160	216/9376	1.89907407407407	JUN/ABCA1/NFKBIA/CCL3L1/SOD2/STAT3/ABCG1	1.76136356997502
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	7/160	217/9376	1.89032258064516	JUN/RPS6KA2/STAT3/CYP1B1/FGF10/STAT5A/PRKCB	1.74834695761471
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	4/160	95/9376	2.46736842105263	JUN/CXCL12/CCL3L1/HLA-DRB5	1.89399130662236
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	2/160	29/9376	4.04137931034483	RASSF4/RASSF2	2.16126420806365
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	5/160	140/9376	2.09285714285714	RPS6/SPP1/MAP1LC3B/PIK3R6/GNG4	1.7165633958127
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	4/160	100/9376	2.344	CCL4L2/CXCL12/CCL3L1/CCL4	1.78030042379512
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	3/160	65/9376	2.70461538461538	CGA/SPP1/PRKCB	1.81701835828933
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/160	66/9376	2.66363636363636	JUN/HLA-DRB5/STAT3	1.78702212019073
Human Diseases	Immune disease	hsa05310	Asthma	2/160	32/9376	3.6625	HLA-DRB5/PRG2	1.98779954661869
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	4/160	105/9376	2.23238095238095	JUN/MAP1LC3B/SQSTM1/UBC	1.67321108359297
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	7/160	235/9376	1.74553191489362	MT-CO3/RPS6KA2/RPS6/MT-ATP8/ACTG1/MT-ND4L/MT-CYB	1.5250276318966
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/160	109/9376	2.15045871559633	RPS6KA2/NFKBIA/STAT3/PRKCB	1.59180220698396
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	9/160	333/9376	1.58378378378378	COL6A1/COL6A3/SPP1/COL6A2/COL1A1/COL1A2/TNXB/HLA-B/LAMB1	1.42919758903759
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/160	70/9376	2.51142857142857	ACTG1/HLA-DRB5/HLA-B	1.67235903216273
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	3/160	71/9376	2.47605633802817	CGA/STAT3/STAT5A	1.64493338901339
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	3/160	73/9376	2.40821917808219	STAT3/STAT5A/PRKCB	1.59145576072009
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/160	75/9376	2.344	CGA/TG/PRKCB	1.53971192973809
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	2/160	38/9376	3.08421052631579	NAPRT/AOX1	1.69621478722169
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	6/160	205/9376	1.71512195121951	JUN/DDX3X/NFKBIA/STAT3/HLA-B/STAT5A	1.36402738496325
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/160	76/9376	2.31315789473684	PLIN2/UBC/SCD5	1.51445602514211
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/160	39/9376	3.00512820512821	HLA-DRB5/HLA-B	1.65327525894361
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/160	78/9376	2.25384615384615	JUN/C1R/C1S	1.46511319271932
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/160	122/9376	1.92131147540984	CSH1/STAT3/STAT5A/PRKCB	1.34957195516916
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/160	80/9376	2.1975	RPS6/STAT3/PRKCB	1.4172512690631
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	8/160	308/9376	1.52207792207792	TGM2/MT-CO3/MT-ATP8/SOD2/SLC25A6/MT-ND4L/MT-CYB/TAF4B	1.22752212014973
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	6/160	214/9376	1.64299065420561	JUN/NFKBIA/HLA-B/PAK3/GNG4/PRKCB	1.25369184244325
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/160	42/9376	2.79047619047619	CYP1B1/AOX1	1.53226433693793
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/160	42/9376	2.79047619047619	MAP1LC3B/FTL	1.53226433693793
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	3/160	83/9376	2.11807228915663	CCL4L2/NFKBIA/CCL4	1.34804800474352
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/160	44/9376	2.66363636363636	HLA-DRB5/HLA-B	1.45737654005931
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/160	173/9376	1.69364161849711	ACTG1/NFKBIA/HLA-DRB5/SLC25A6/PRKCB	1.21329911260049
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	7/160	268/9376	1.53059701492537	MT-CO3/MT-ATP8/SLC25A6/MT-ND4L/MT-CYB/UBC/TXN	1.16116806967077
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/160	45/9376	2.60444444444444	ABCA1/ABCG1	1.4214816000185
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/160	45/9376	2.60444444444444	HLA-DRB5/HLA-B	1.4214816000185
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	6/160	224/9376	1.56964285714286	JUN/NFKBIA/HLA-DRB5/SLC25A6/HLA-B/STAT5A	1.13695442423817
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	3/160	87/9376	2.02068965517241	MT-CO3/TPM2/MT-CYB	1.26021096633286
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	5/160	178/9376	1.64606741573034	SFRP2/JUN/SERPINF1/NOTUM/PRKCB	1.14660949301991
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/160	88/9376	1.99772727272727	CFD/C1R/C1S	1.23898621079286
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/160	90/9376	1.95333333333333	JUN/NFKBIA/STAT3	1.19736370627614
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	4/160	138/9376	1.69855072463768	MT-CO3/MT-ATP8/MT-ND4L/MT-CYB	1.08923831142509
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/160	138/9376	1.69855072463768	JUN/RPS6KA2/ACTG1/NFKBIA	1.08923831142509
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/160	50/9376	2.344	CXCL12/HLA-DRB5	1.25548336232942
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/160	93/9376	1.89032258064516	JUN/CGA/PRKCB	1.13689166829308
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	5/160	187/9376	1.5668449197861	JUN/NFKBIA/MAP1LC3B/TNFAIP3/TXN	1.03163325362311
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/160	94/9376	1.87021276595745	JUN/NFKBIA/TNFAIP3	1.11723103518867
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/160	52/9376	2.25384615384615	CGA/CYP1B1	1.19459086112561
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/160	142/9376	1.65070422535211	JUN/ACTG1/SQSTM1/TXN	1.02945474664153
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/160	15/9376	3.90666666666667	B4GALNT1	1.4844108962516
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/160	248/9376	1.41774193548387	JUN/RPS3/ACTG1/NFKBIA/TXN/PAK3	0.878456975545618
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/160	200/9376	1.465	JUN/RPS3/ACTG1/NFKBIA/PAK3	0.875821585808958
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/160	103/9376	1.70679611650485	JUN/NFKBIA/CCL3L1	0.950335676852205
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	6/160	253/9376	1.3897233201581	JUN/ACTG1/NFKBIA/MAP1LC3B/SQSTM1/UBC	0.827984512601373
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/160	155/9376	1.51225806451613	ACTG1/C1R/HLA-DRB5/HLA-B	0.847305525998469
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	4/160	160/9376	1.465	VCAN/HLA-DRB5/HLA-B/VSIR	0.781656795133007
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/160	21/9376	2.79047619047619	CHST11	1.08225773422821
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/160	115/9376	1.52869565217391	PIK3R6/GNG4/PRKCB	0.751623090421056
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/160	67/9376	1.74925373134328	LDHA/GAPDHS	0.810940885833454
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/160	67/9376	1.74925373134328	RPS6KA2/PRKCB	0.810940885833454
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/160	116/9376	1.51551724137931	ACTG1/CXCL12/PRKCB	0.736107245518861
NA	NA	hsa04081	Hormone signaling	5/160	219/9376	1.337899543379	CGA/CSH1/STAT3/STAT5A/GNG4	0.666664687615338
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/160	168/9376	1.3952380952381	CSH1/STAT3/AOX1/STAT5A	0.681091059860486
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/160	68/9376	1.72352941176471	STAT3/STAT5A	0.788963397879592
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/160	23/9376	2.54782608695652	ARG2	0.979230674379288
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/160	69/9376	1.69855072463768	JUN/PRKCB	0.767347411421645
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/160	119/9376	1.47731092436975	JUN/NFKBIA/TNFAIP3	0.690421202108454
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/160	70/9376	1.67428571428571	NFKBIA/STAT3	0.746080778053696
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/160	70/9376	1.67428571428571	JUN/PAK3	0.746080778053696
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/160	120/9376	1.465	JUN/RPS6KA2/NFKBIA	0.675470364242552
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/160	71/9376	1.65070422535211	JUN/NFKBIA	0.725151932942925
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/160	122/9376	1.44098360655738	JUN/NFKBIA/PAK3	0.645969494556057
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/160	72/9376	1.62777777777778	DDX3X/NFKBIA	0.704549858836597
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/160	232/9376	1.26293103448276	TMSB4X/ACTG1/CXCL12/PAK3/FGF10	0.534308558052956
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/160	27/9376	2.17037037037037	SCD5	0.802411265091301
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/160	76/9376	1.54210526315789	ACTG1/PRKCB	0.625206294948445
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/160	77/9376	1.52207792207792	NFKBIA/STAT5A	0.606089783090122
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/160	184/9376	1.27391304347826	CXCL12/SEMA5A/EPHA4/PAK3	0.494414288819138
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/160	82/9376	1.42926829268293	HLA-DRB5/HLA-B	0.514409285917683
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/160	137/9376	1.28321167883212	JUN/ACTG1/NFKBIA	0.439980425063365
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/160	83/9376	1.41204819277108	SOD2/PRDX5	0.496802174161945
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/160	32/9376	1.83125	LDHA	0.620604083803487
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	9/160	480/9376	1.09875	MT-CO3/MT-ATP8/MAP1LC3B/SQSTM1/SLC25A6/MT-ND4L/MT-CYB/UBC/PRKCB	0.292640703628221
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/160	142/9376	1.23802816901408	JUN/NFKBIA/SQSTM1	0.376575437624282
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/160	368/9376	1.11467391304348	MT-CO3/MT-ATP8/ACTG1/MAP1LC3B/SQSTM1/MT-ND4L/MT-CYB	0.295698246640177
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	3/160	143/9376	1.22937062937063	C1R/HLA-DRB5/C1S	0.364173888754218
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/160	89/9376	1.31685393258427	GNG4/PRKCB	0.395722531541912
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/160	91/9376	1.28791208791209	GNG4/PRKCB	0.363633626869239
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/160	149/9376	1.17986577181208	MT-ND4L/GNG4/PRKCB	0.291598842691708
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/160	37/9376	1.58378378378378	AOX1	0.468788660381233
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/160	37/9376	1.58378378378378	PRKCB	0.468788660381233
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/160	93/9376	1.26021505376344	ACTG1/RADIL	0.332279932037348
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/160	93/9376	1.26021505376344	CST3/PRKCB	0.332279932037348
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/160	93/9376	1.26021505376344	NFKBIA/LAMB1	0.332279932037348
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/160	38/9376	1.54210526315789	PRKCB	0.441187179504632
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	7/160	388/9376	1.05721649484536	MT-CO3/MT-ATP8/SLC25A6/MT-ND4L/MT-CYB/APOE/BACE2	0.151663116598268
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/160	97/9376	1.20824742268041	GNG4/PRKCB	0.27163724145108
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/160	157/9376	1.11974522292994	ABCA1/ARG2/SLC16A1	0.199361141680949
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/160	157/9376	1.11974522292994	SQSTM1/SLC25A6/HLA-B	0.199361141680949
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/160	157/9376	1.11974522292994	JUN/MT-CO3/MT-CYB	0.199361141680949
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/160	99/9376	1.18383838383838	JUN/PRKCB	0.242283818030134
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/160	99/9376	1.18383838383838	ACTG1/TPM2	0.242283818030134
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/160	275/9376	1.06545454545455	MT-CO3/MT-ATP8/SLC25A6/MT-ND4L/MT-CYB	0.145156336059756
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/160	158/9376	1.1126582278481	RPS6KA2/RPS6/PRKCB	0.188168751522215
NA	NA	hsa04382	Cornified envelope formation	4/160	217/9376	1.08018433179724	S100A4/S100A6/KRT19/S100A16	0.157459819164058
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/160	100/9376	1.172	CD9/HLA-DRB5	0.227836066140446
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/160	43/9376	1.36279069767442	ABCA1	0.314162348011273
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/160	44/9376	1.33181818181818	TAF4B	0.29067892738888
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/160	105/9376	1.11619047619048	JUN/NFKBIA	0.157752513290837
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/160	105/9376	1.11619047619048	ACTG1/TPM2	0.157752513290837
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/160	46/9376	1.27391304347826	FTL	0.245372113608547
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/160	108/9376	1.08518518518519	EEF1A1/EIF4A3	0.117316023407214
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	3/160	169/9376	1.04023668639053	MAP1LC3B/SQSTM1/UBC	0.0695473978533505
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/160	47/9376	1.2468085106383	LDHA	0.223494021516135
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/160	170/9376	1.03411764705882	JUN/ACTG1/MYL6	0.0591483241247077
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/160	48/9376	1.22083333333333	AOX1	0.20209956296122
NA	NA	hsa03272	Virion - Hepatitis viruses	1/160	48/9376	1.22083333333333	CD9	0.20209956296122
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/160	48/9376	1.22083333333333	PRKCB	0.20209956296122
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/160	110/9376	1.06545454545455	THSD4/FMOD	0.0909838693294082
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/160	49/9376	1.19591836734694	COLGALT2	0.181165960609441
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/160	49/9376	1.19591836734694	JUN	0.181165960609441
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/160	50/9376	1.172	ARG2	0.160671977917158
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	5/160	298/9376	0.983221476510067	CCL4L2/CSH1/CXCL12/CCL3L1/CCL4	-0.038782980295823
NA	NA	hsa04517	IgSF CAM signaling	5/160	299/9376	0.979933110367893	ACTG1/PAK3/SPTBN1/MYL6/PRKCB	-0.0464642450340138
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/160	238/9376	0.984873949579832	PAK3/FGF10/GNG4/PRKCB	-0.0311431718237552
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/160	51/9376	1.14901960784314	ACTG1	0.140597785546078
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/160	115/9376	1.01913043478261	GNG4/PRKCB	0.0271968881402355
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/160	115/9376	1.01913043478261	NACA/PRKCB	0.0271968881402355
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/160	116/9376	1.01034482758621	GNG4/PRKCB	0.0147713828532214
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/160	180/9376	0.976666666666667	NFKBIA/HLA-DRB5/HLA-B	-0.0416474056540038
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/160	53/9376	1.10566037735849	PRKCB	0.101635785169619
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/160	54/9376	1.08518518518519	LDHA	0.0827143381369132
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/160	55/9376	1.06545454545455	B4GALNT1	0.0641452199320593
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/160	122/9376	0.960655737704918	EEF2/SCD5	-0.0576329660570459
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/160	122/9376	0.960655737704918	ACTG1/PRKCB	-0.0576329660570459
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/160	57/9376	1.0280701754386	SCD5	0.0280073678479148
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/160	59/9376	0.993220338983051	NME2	-0.00688288216117219
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/160	59/9376	0.993220338983051	CGA	-0.00688288216117219
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/160	60/9376	0.976666666666667	PRKCB	-0.0238897754164416
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/160	60/9376	0.976666666666667	PRKCB	-0.0238897754164416
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/160	194/9376	0.906185567010309	ACTG1/TPM2/MYL6	-0.173970765842079
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	5/160	323/9376	0.907120743034056	VIM/STAT3/TNXB/CYP1B1/PRKCB	-0.223819607526098
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/160	195/9376	0.901538461538462	ACTG1/SLC25A6/PRKCB	-0.183068374687518
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/160	61/9376	0.960655737704918	FTL	-0.0406190059655217
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/160	62/9376	0.945161290322581	SOD2	-0.0570807080972204
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/160	63/9376	0.93015873015873	COLGALT2	-0.073284477665873
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/160	63/9376	0.93015873015873	PTGDS	-0.073284477665873
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/160	133/9376	0.881203007518797	SOD2/STAT3	-0.181802221808974
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/160	133/9376	0.881203007518797	HLA-B/PRKCB	-0.181802221808974
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/160	133/9376	0.881203007518797	GNG4/PRKCB	-0.181802221808974
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/160	134/9376	0.874626865671642	MYL6/PRKCB	-0.192596458485492
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/160	66/9376	0.887878787878788	CYP1B1	-0.120436827772417
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/160	139/9376	0.843165467625899	JUN/KRT19	-0.24544716383669
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/160	68/9376	0.861764705882353	AOX1	-0.150736909350979
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/160	70/9376	0.837142857142857	CYP1B1	-0.180197476055342
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/160	212/9376	0.829245283018868	ACTG1/FGF10/PRKCB	-0.331338953546817
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/160	71/9376	0.825352112676056	LDHA	-0.194629523127538
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/160	144/9376	0.813888888888889	NFKBIA/SCD5	-0.296537789989177
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/160	144/9376	0.813888888888889	SLC25A6/PRKCB	-0.296537789989177
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/160	73/9376	0.802739726027397	AOX1	-0.222927655198145
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/160	73/9376	0.802739726027397	FGF10	-0.222927655198145
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/160	148/9376	0.791891891891892	JUN/FGF10	-0.336233098174677
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/160	75/9376	0.781333333333333	ARG2	-0.250508686981197
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/160	76/9376	0.771052631578947	PRKCB	-0.264043435245217
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/160	77/9376	0.761038961038961	STAT3	-0.277414229076076
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/160	78/9376	0.751282051282051	ACTG1	-0.29062572534514
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/160	154/9376	0.761038961038961	NME2/NAPRT	-0.393957430141811
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/160	154/9376	0.761038961038961	PIK3R6/TPM2	-0.393957430141811
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/160	79/9376	0.741772151898734	CYP1B1	-0.303682385876664
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/160	226/9376	0.77787610619469	JUN/CGA/NFKBIA	-0.445362193226158
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/160	156/9376	0.751282051282051	NFKBIA/STAT3	-0.412741713086572
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/160	82/9376	0.714634146341463	NME2	-0.341965263933914
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/160	300/9376	0.781333333333333	JUN/RPS6KA2/FGF10/PRKCB	-0.507189629438131
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/160	85/9376	0.689411764705882	NME2	-0.378998621600181
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/160	86/9376	0.681395348837209	PRKCB	-0.391082044288589
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/160	86/9376	0.681395348837209	ACTG1	-0.391082044288589
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/160	87/9376	0.673563218390805	JUN	-0.403040444187537
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/160	166/9376	0.706024096385542	SLC25A6/PIK3R6	-0.503512619100729
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/160	89/9376	0.658426966292135	PRKCB	-0.426594502087735
Genetic Information Processing	Transcription	hsa03040	Spliceosome	3/160	243/9376	0.723456790123457	DDX5/HNRNPC/EIF4A3	-0.575484729253462
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/160	90/9376	0.651111111111111	SOD2	-0.438196041690801
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/160	170/9376	0.689411764705882	ACTG1/PRKCB	-0.538453709273202
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/160	254/9376	0.692125984251968	SLC25A6/FGF10/PRKCB	-0.655419347491688
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/160	98/9376	0.597959183673469	PRKCB	-0.527145369977707
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/160	98/9376	0.597959183673469	PRKCB	-0.527145369977707
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/160	98/9376	0.597959183673469	PRKCB	-0.527145369977707
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/160	99/9376	0.591919191919192	JUN	-0.537816826836122
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/160	99/9376	0.591919191919192	PRKCB	-0.537816826836122
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/160	101/9376	0.58019801980198	PRKCB	-0.558885197368666
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/160	102/9376	0.574509803921569	PRKCB	-0.56928598775358
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/160	103/9376	0.568932038834951	EIF4A3	-0.579600330387883
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/160	106/9376	0.552830188679245	NFKBIA	-0.610042284071867
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/160	107/9376	0.547663551401869	LDHA	-0.620028179680741
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/160	110/9376	0.532727272727273	RPS6KA2	-0.64952373382383
NA	NA	hsa04082	Neuroactive ligand signaling	2/160	199/9376	0.58894472361809	GNG4/PRKCB	-0.77223733797524
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/160	117/9376	0.500854700854701	ACTG1	-0.715833914999334
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/160	125/9376	0.4688	PRKCB	-0.787758556081793
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/160	128/9376	0.4578125	NME2	-0.813776176418661
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/160	138/9376	0.42463768115942	RPS6KA2	-0.897152717086638
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/160	138/9376	0.42463768115942	RPS6	-0.897152717086638
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/160	142/9376	0.412676056338028	UBC	-0.92918318041021
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/160	144/9376	0.406944444444444	STAT3	-0.94493758451775
NA	NA	hsa04519	Cadherin signaling	4/160	404/9376	0.58019801980198	VIM/ACTG1/NFKBIA/KRT19	-1.13648819616216
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/160	149/9376	0.393288590604027	PIK3R6	-0.983602066392925
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/160	150/9376	0.390666666666667	FGF10	-0.99121584900701
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/160	157/9376	0.373248407643312	ACTG1	-1.04346469901092
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/160	174/9376	0.336781609195402	DNAJA1	-1.16349485375454
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/160	181/9376	0.323756906077348	HLA-DRB5	-1.21043273450323
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/160	183/9376	0.320218579234973	RMRP	-1.22360319387702
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/160	191/9376	0.306806282722513	GNG4	-1.275281670465
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/160	201/9376	0.291542288557214	DDX5	-1.33777575440497
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/160	250/9376	0.2344	HLA-B	-1.61661309870787
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/160	370/9376	0.316756756756757	CGA/CSH1	-1.76678878059229