ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 51/237 175/18639 0.291428571428571 22.9195660036166 9.49252808618657e-56 5.03103988567888e-53 GO:0019843 rRNA binding 15/237 65/18639 0.230769230769231 18.1489776046738 2.77696302257599e-15 6.17825028206746e-13 GO:0005201 extracellular matrix structural constituent 21/237 168/18639 0.125 9.83069620253165 3.49712280117026e-15 6.17825028206746e-13 GO:0030020 extracellular matrix structural constituent conferring tensile strength 8/237 44/18639 0.181818181818182 14.2991944764097 7.25214002576621e-08 9.60908553414023e-06 GO:0019838 growth factor binding 12/237 136/18639 0.0882352941176471 6.93931496649293 1.70863867964144e-07 1.81115700041993e-05 GO:0004857 enzyme inhibitor activity 19/237 416/18639 0.0456730769230769 3.59198515092502 1.68035629257667e-06 0.00014109667710878 GO:0050840 extracellular matrix binding 8/237 67/18639 0.119402985074627 9.39051577555262 2.07536035907476e-06 0.00014109667710878 GO:0008201 heparin binding 12/237 172/18639 0.0697674418604651 5.48690020606417 2.12976116390612e-06 0.00014109667710878 GO:0005539 glycosaminoglycan binding 14/237 242/18639 0.0578512396694215 4.54974369703944 2.80067703876415e-06 0.000164928758949445 GO:0005520 insulin-like growth factor binding 5/237 19/18639 0.263157894736842 20.6962025316456 3.20345488957187e-06 0.000169783109147309 GO:0048407 platelet-derived growth factor binding 4/237 11/18639 0.363636363636364 28.5983889528193 7.84116053200132e-06 0.000346317923496725 GO:1990948 ubiquitin ligase inhibitor activity 4/237 11/18639 0.363636363636364 28.5983889528193 7.84116053200132e-06 0.000346317923496725 GO:0048027 mRNA 5'-UTR binding 5/237 24/18639 0.208333333333333 16.3844936708861 1.1117070094817e-05 0.00045323439617331 GO:0031994 insulin-like growth factor I binding 4/237 13/18639 0.307692307692308 24.1986368062317 1.66519643045396e-05 0.000630395791528998 GO:0045296 cadherin binding 15/237 334/18639 0.0449101796407186 3.53198665959221 2.60255637327102e-05 0.00091956991855576 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/237 15/18639 0.266666666666667 20.9721518987342 3.11595984466971e-05 0.00103216169854684 GO:0061134 peptidase regulator activity 12/237 226/18639 0.0530973451327434 4.17587095328778 3.3977899770108e-05 0.00105931099283278 GO:1901681 sulfur compound binding 13/237 275/18639 0.0472727272727273 3.71779056386651 5.36337575326406e-05 0.00157921619401664 GO:0003746 translation elongation factor activity 4/237 18/18639 0.222222222222222 17.4767932489451 6.77864692580309e-05 0.00189088572140823 GO:0008135 translation factor activity, RNA binding 7/237 83/18639 0.0843373493975904 6.63275888363581 8.98573012310106e-05 0.00238121848262178 GO:0180051 translation factor activity 7/237 84/18639 0.0833333333333333 6.55379746835443 9.69786102343787e-05 0.00244755540115337 GO:0005178 integrin binding 9/237 161/18639 0.0559006211180124 4.39633618995204 0.000223278564296095 0.00537898359440591 GO:0043236 laminin binding 4/237 29/18639 0.137931034482759 10.8476647752073 0.000471445426959752 0.0108637424473334 GO:0001968 fibronectin binding 4/237 30/18639 0.133333333333333 10.4860759493671 0.000538587131052064 0.0117905453202851 GO:0004864 protein phosphatase inhibitor activity 5/237 53/18639 0.0943396226415094 7.41939336040124 0.000556157798126655 0.0117905453202851 GO:0061135 endopeptidase regulator activity 9/237 184/18639 0.0489130434782609 3.84679416620804 0.000594569920539635 0.0121200791494618 GO:0140313 molecular sequestering activity 5/237 55/18639 0.0909090909090909 7.14959723820483 0.000660463733184141 0.0129646584662072 GO:0019212 phosphatase inhibitor activity 5/237 56/18639 0.0892857142857143 7.02192585895118 0.000717792785998895 0.0135867920206934 GO:0016504 peptidase activator activity 5/237 57/18639 0.087719298245614 6.89873417721519 0.000778760983875575 0.0141133904459778 GO:0016209 antioxidant activity 6/237 86/18639 0.0697674418604651 5.48690020606417 0.000798871157319496 0.0141133904459778 GO:0140328 floppase activity 3/237 16/18639 0.1875 14.7460443037975 0.0010057504147987 0.0171950877368811 GO:0055106 ubiquitin-protein transferase regulator activity 4/237 36/18639 0.111111111111111 8.73839662447257 0.00109062473132215 0.0180634721125232 GO:0008525 phosphatidylcholine transporter activity 3/237 18/18639 0.166666666666667 13.1075949367089 0.00143827115365128 0.0230995064071266 GO:0002020 protease binding 7/237 136/18639 0.0514705882352941 4.04793373045421 0.00179168375456864 0.0279291879388641 GO:0043021 ribonucleoprotein complex binding 8/237 177/18639 0.0451977401129944 3.55460201673461 0.00196300272000266 0.0297254697600403 GO:0005518 collagen binding 5/237 72/18639 0.0694444444444444 5.46149789029536 0.00223110733194899 0.0328468579425824 GO:0019888 protein phosphatase regulator activity 6/237 107/18639 0.0560747663551402 4.41003194132261 0.00246369913712248 0.0352908254777004 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/237 22/18639 0.136363636363636 10.7243958573072 0.00261455940454132 0.0364662232738658 GO:0043022 ribosome binding 6/237 112/18639 0.0535714285714286 4.2131555153707 0.00309526350622689 0.0420638373923141 GO:0120020 cholesterol transfer activity 3/237 25/18639 0.12 9.43746835443038 0.00379688775179316 0.0496459971193086 GO:0019208 phosphatase regulator activity 6/237 117/18639 0.0512820512820513 4.03310613437196 0.00384053939979557 0.0496459971193086 GO:0004866 endopeptidase inhibitor activity 7/237 161/18639 0.0434782608695652 3.41937259218492 0.00458840732817442 0.0571566172427585 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/237 27/18639 0.111111111111111 8.73839662447257 0.00473936370178395 0.0571566172427585 GO:0008083 growth factor activity 7/237 162/18639 0.0432098765432099 3.39826535396156 0.00474507765788939 0.0571566172427585 GO:0030414 peptidase inhibitor activity 7/237 169/18639 0.0414201183431953 3.25750880083889 0.00595733246301282 0.0701641378977065 GO:0004867 serine-type endopeptidase inhibitor activity 5/237 95/18639 0.0526315789473684 4.13924050632911 0.00730738696704414 0.0841938063594216 GO:0120015 sterol transfer activity 3/237 32/18639 0.09375 7.37302215189873 0.00767108336876627 0.0865037060733218 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/237 11/18639 0.181818181818182 14.2991944764097 0.00820995973421141 0.0886174460802312 GO:0097493 structural molecule activity conferring elasticity 2/237 11/18639 0.181818181818182 14.2991944764097 0.00820995973421141 0.0886174460802312 GO:0140311 protein sequestering activity 3/237 33/18639 0.0909090909090909 7.14959723820483 0.00836013642266332 0.0886174460802312 GO:0097371 MDM2/MDM4 family protein binding 2/237 12/18639 0.166666666666667 13.1075949367089 0.00976989987659456 0.101530332050885 GO:0005506 iron ion binding 6/237 154/18639 0.038961038961039 3.06411310208779 0.0140348859652439 0.141878754241604 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/237 40/18639 0.075 5.89841772151899 0.0141878754241604 0.141878754241604 GO:0061578 K63-linked deubiquitinase activity 2/237 15/18639 0.133333333333333 10.4860759493671 0.0151586991987681 0.148779825469391 GO:0008307 structural constituent of muscle 3/237 42/18639 0.0714285714285714 5.61754068716094 0.0161835994450356 0.153166209033373 GO:0042056 chemoattractant activity 3/237 42/18639 0.0714285714285714 5.61754068716094 0.0161835994450356 0.153166209033373 GO:0003724 RNA helicase activity 4/237 77/18639 0.051948051948052 4.08548413611705 0.0167372060116579 0.1556266523891 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/237 43/18639 0.0697674418604651 5.48690020606417 0.0172374886477717 0.157514982471017 GO:0008186 ATP-dependent activity, acting on RNA 4/237 79/18639 0.0506329113924051 3.9820541579875 0.0182241242859098 0.158656328952086 GO:0046332 SMAD binding 4/237 79/18639 0.0506329113924051 3.9820541579875 0.0182241242859098 0.158656328952086 GO:0030547 signaling receptor inhibitor activity 3/237 44/18639 0.0681818181818182 5.36219792865362 0.0183288787214927 0.158656328952086 GO:0048306 calcium-dependent protein binding 4/237 80/18639 0.05 3.93227848101266 0.0189973729121591 0.158656328952086 GO:0070492 oligosaccharide binding 2/237 17/18639 0.117647058823529 9.2524199553239 0.0193099746231113 0.158656328952086 GO:0008009 chemokine activity 3/237 45/18639 0.0666666666666667 5.24303797468354 0.019457851663935 0.158656328952086 GO:0140303 intramembrane lipid transporter activity 3/237 45/18639 0.0666666666666667 5.24303797468354 0.019457851663935 0.158656328952086 GO:0043395 heparan sulfate proteoglycan binding 2/237 19/18639 0.105263157894737 8.27848101265823 0.0238794586950923 0.188897210573118 GO:0046624 sphingolipid transporter activity 2/237 19/18639 0.105263157894737 8.27848101265823 0.0238794586950923 0.188897210573118 GO:0004252 serine-type endopeptidase activity 6/237 176/18639 0.0340909090909091 2.68109896432681 0.0252396471051646 0.196720778907901 GO:0043024 ribosomal small subunit binding 2/237 20/18639 0.1 7.86455696202532 0.0263136172057282 0.200210295401911 GO:0003727 single-stranded RNA binding 4/237 89/18639 0.0449438202247191 3.53463234248329 0.0268723934018168 0.200210295401911 GO:0003743 translation initiation factor activity 3/237 51/18639 0.0588235294117647 4.62620997766195 0.0270227025854685 0.200210295401911 GO:0030246 carbohydrate binding 8/237 280/18639 0.0285714285714286 2.24701627486438 0.0271983797527125 0.200210295401911 GO:0005080 protein kinase C binding 3/237 52/18639 0.0576923076923077 4.53724440116845 0.0284152028321017 0.203827750256183 GO:0035613 RNA stem-loop binding 2/237 21/18639 0.0952380952380952 7.49005424954792 0.0288435495645542 0.203827750256183 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/237 21/18639 0.0952380952380952 7.49005424954792 0.0288435495645542 0.203827750256183 GO:0015485 cholesterol binding 3/237 54/18639 0.0555555555555556 4.36919831223629 0.03131250696511 0.216587243476551 GO:0061133 endopeptidase activator activity 2/237 22/18639 0.0909090909090909 7.14959723820483 0.0314664485805555 0.216587243476551 GO:0008236 serine-type peptidase activity 6/237 194/18639 0.0309278350515464 2.4323372047501 0.0379493573466202 0.25786101786806 GO:0031625 ubiquitin protein ligase binding 8/237 302/18639 0.0264900662251656 2.08332634755638 0.0397817475589995 0.264110253303242 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/237 25/18639 0.08 6.29164556962025 0.03986569861181 0.264110253303242 GO:0017171 serine hydrolase activity 6/237 198/18639 0.0303030303030303 2.38319907940161 0.041241193949509 0.267079381660288 GO:0008143 poly(A) binding 2/237 26/18639 0.0769230769230769 6.04965920155794 0.0428334857379707 0.267079381660288 GO:0050681 nuclear androgen receptor binding 2/237 26/18639 0.0769230769230769 6.04965920155794 0.0428334857379707 0.267079381660288 GO:0050750 low-density lipoprotein particle receptor binding 2/237 26/18639 0.0769230769230769 6.04965920155794 0.0428334857379707 0.267079381660288 GO:0070412 R-SMAD binding 2/237 26/18639 0.0769230769230769 6.04965920155794 0.0428334857379707 0.267079381660288 GO:0120013 lipid transfer activity 3/237 65/18639 0.0461538461538462 3.62979552093476 0.0498750277607876 0.307369357130435 GO:0003785 actin monomer binding 2/237 29/18639 0.0689655172413793 5.42383238760367 0.0522053975712258 0.318032881755743 GO:0044389 ubiquitin-like protein ligase binding 8/237 322/18639 0.0248447204968944 1.95392719553424 0.0541650772482609 0.320799674751626 GO:0005200 structural constituent of cytoskeleton 4/237 112/18639 0.0357142857142857 2.80877034358047 0.0547630785973415 0.320799674751626 GO:0005548 phospholipid transporter activity 3/237 68/18639 0.0441176470588235 3.46965748324646 0.0556859812776408 0.320799674751626 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/237 68/18639 0.0441176470588235 3.46965748324646 0.0556859812776408 0.320799674751626 GO:0032934 sterol binding 3/237 68/18639 0.0441176470588235 3.46965748324646 0.0556859812776408 0.320799674751626 GO:0070325 lipoprotein particle receptor binding 2/237 31/18639 0.0645161290322581 5.07390771743569 0.0588195282113024 0.330267997113792 GO:0015399 primary active transmembrane transporter activity 5/237 166/18639 0.0301204819277108 2.36884245844136 0.0611403887808527 0.330267997113792 GO:0031369 translation initiation factor binding 2/237 32/18639 0.0625 4.91534810126582 0.0622294245341382 0.330267997113792 GO:0051059 NF-kappaB binding 2/237 32/18639 0.0625 4.91534810126582 0.0622294245341382 0.330267997113792 GO:0070717 poly-purine tract binding 2/237 32/18639 0.0625 4.91534810126582 0.0622294245341382 0.330267997113792 GO:0071813 lipoprotein particle binding 2/237 32/18639 0.0625 4.91534810126582 0.0622294245341382 0.330267997113792 GO:0071814 protein-lipid complex binding 2/237 32/18639 0.0625 4.91534810126582 0.0622294245341382 0.330267997113792 GO:1990782 protein tyrosine kinase binding 4/237 117/18639 0.0341880341880342 2.68873742291464 0.0623147164365646 0.330267997113792 GO:0042379 chemokine receptor binding 3/237 72/18639 0.0416666666666667 3.27689873417722 0.063910468307224 0.335371764384443 GO:0015035 protein-disulfide reductase activity 2/237 34/18639 0.0588235294117647 4.62620997766195 0.0692436401639203 0.356302226086192 GO:0019825 oxygen binding 2/237 34/18639 0.0588235294117647 4.62620997766195 0.0692436401639203 0.356302226086192 GO:0005319 lipid transporter activity 5/237 178/18639 0.0280898876404494 2.20914521405206 0.0773060864926653 0.393963710010698 GO:0043394 proteoglycan binding 2/237 37/18639 0.0540540540540541 4.25111187136504 0.0802186629046052 0.404913250851817 GO:0035591 signaling adaptor activity 4/237 129/18639 0.0310077519379845 2.4386223138063 0.0825392792649252 0.412696396324626 GO:0030971 receptor tyrosine kinase binding 3/237 81/18639 0.037037037037037 2.91279887482419 0.0843040829901904 0.417580971820569 GO:0015078 proton transmembrane transporter activity 5/237 185/18639 0.027027027027027 2.12555593568252 0.0877011844481036 0.428104738403465 GO:0005179 hormone activity 4/237 132/18639 0.0303030303030303 2.38319907940161 0.0880441820490144 0.428104738403465 GO:0001540 amyloid-beta binding 3/237 83/18639 0.036144578313253 2.84261095012963 0.0891712640640008 0.429643363217458 GO:0015036 disulfide oxidoreductase activity 2/237 40/18639 0.05 3.93227848101266 0.0916887056037509 0.43779291864854 GO:0042169 SH2 domain binding 2/237 41/18639 0.0487804878048781 3.83636924976845 0.0956128902384858 0.452453855592835 GO:0042277 peptide binding 6/237 249/18639 0.0240963855421687 1.89507396675309 0.0988814087120139 0.463780058560773 GO:0019903 protein phosphatase binding 4/237 144/18639 0.0277777777777778 2.18459915611814 0.111757037163932 0.483402224543351 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/237 45/18639 0.0444444444444444 3.49535864978903 0.111764377645711 0.483402224543351 GO:0042605 peptide antigen binding 2/237 45/18639 0.0444444444444444 3.49535864978903 0.111764377645711 0.483402224543351 GO:0043178 alcohol binding 3/237 92/18639 0.0326086956521739 2.56452944413869 0.112453059682172 0.483402224543351 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/237 46/18639 0.0434782608695652 3.41937259218492 0.1159071008861 0.483402224543351 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/237 46/18639 0.0434782608695652 3.41937259218492 0.1159071008861 0.483402224543351 GO:0140359 ABC-type transporter activity 2/237 47/18639 0.0425531914893617 3.34661998384056 0.120088360511126 0.483402224543351 GO:0005131 growth hormone receptor binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0005522 profilin binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0008190 eukaryotic initiation factor 4E binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0030957 Tat protein binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0032356 oxidized DNA binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0035374 chondroitin sulfate binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0051880 G-quadruplex DNA binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0070513 death domain binding 1/237 10/18639 0.1 7.86455696202532 0.120145880274709 0.483402224543351 GO:0140693 molecular condensate scaffold activity 2/237 48/18639 0.0416666666666667 3.27689873417722 0.124306517687214 0.483402224543351 GO:0000510 H3-H4 histone complex chaperone activity 4/237 151/18639 0.0264900662251656 2.08332634755638 0.126767220550686 0.483402224543351 GO:0140584 chromatin extrusion motor activity 4/237 151/18639 0.0264900662251656 2.08332634755638 0.126767220550686 0.483402224543351 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/237 151/18639 0.0264900662251656 2.08332634755638 0.126767220550686 0.483402224543351 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/237 151/18639 0.0264900662251656 2.08332634755638 0.126767220550686 0.483402224543351 GO:0015616 DNA translocase activity 4/237 152/18639 0.0263157894736842 2.06962025316456 0.12897798631486 0.483402224543351 GO:0140674 ATP-dependent histone chaperone activity 4/237 152/18639 0.0263157894736842 2.06962025316456 0.12897798631486 0.483402224543351 GO:0061775 cohesin loader activity 4/237 153/18639 0.0261437908496732 2.05609332340531 0.131204839857657 0.483402224543351 GO:0008199 ferric iron binding 1/237 11/18639 0.0909090909090909 7.14959723820483 0.13133947232876 0.483402224543351 GO:0015217 ADP transmembrane transporter activity 1/237 11/18639 0.0909090909090909 7.14959723820483 0.13133947232876 0.483402224543351 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/237 11/18639 0.0909090909090909 7.14959723820483 0.13133947232876 0.483402224543351 GO:0019215 intermediate filament binding 1/237 11/18639 0.0909090909090909 7.14959723820483 0.13133947232876 0.483402224543351 GO:0050786 RAGE receptor binding 1/237 11/18639 0.0909090909090909 7.14959723820483 0.13133947232876 0.483402224543351 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/237 11/18639 0.0909090909090909 7.14959723820483 0.13133947232876 0.483402224543351 GO:0140537 transcription regulator activator activity 1/237 11/18639 0.0909090909090909 7.14959723820483 0.13133947232876 0.483402224543351 GO:0048020 CCR chemokine receptor binding 2/237 50/18639 0.04 3.14582278481013 0.132847144357385 0.485579217306303 GO:0004386 helicase activity 4/237 155/18639 0.0258064516129032 2.02956308697428 0.135706090203059 0.492631697312474 GO:0030544 Hsp70 protein binding 2/237 51/18639 0.0392156862745098 3.08413998510797 0.137166509327667 0.494545917984105 GO:0005126 cytokine receptor binding 6/237 275/18639 0.0218181818181818 1.71590333716916 0.139184404474325 0.497133314756089 GO:0004859 phospholipase inhibitor activity 1/237 12/18639 0.0833333333333333 6.55379746835443 0.142391251642592 0.497133314756089 GO:0035497 cAMP response element binding 1/237 12/18639 0.0833333333333333 6.55379746835443 0.142391251642592 0.497133314756089 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/237 12/18639 0.0833333333333333 6.55379746835443 0.142391251642592 0.497133314756089 GO:0140658 ATP-dependent chromatin remodeler activity 4/237 158/18639 0.0253164556962025 1.99102707899375 0.142574082722501 0.497133314756089 GO:0005246 calcium channel regulator activity 2/237 53/18639 0.0377358490566038 2.9677573441605 0.145895831804559 0.50466207384954 GO:0003689 DNA clamp loader activity 4/237 160/18639 0.025 1.96613924050633 0.147227990111434 0.50466207384954 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/237 54/18639 0.037037037037037 2.91279887482419 0.150302882759922 0.50466207384954 GO:0051287 NAD binding 2/237 54/18639 0.037037037037037 2.91279887482419 0.150302882759922 0.50466207384954 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/237 13/18639 0.0769230769230769 6.04965920155794 0.1533030073392 0.50466207384954 GO:0004535 poly(A)-specific ribonuclease activity 1/237 13/18639 0.0769230769230769 6.04965920155794 0.1533030073392 0.50466207384954 GO:0008035 high-density lipoprotein particle binding 1/237 13/18639 0.0769230769230769 6.04965920155794 0.1533030073392 0.50466207384954 GO:0140333 glycerophospholipid flippase activity 1/237 13/18639 0.0769230769230769 6.04965920155794 0.1533030073392 0.50466207384954 GO:0140666 annealing activity 1/237 13/18639 0.0769230769230769 6.04965920155794 0.1533030073392 0.50466207384954 GO:0140713 histone chaperone activity 4/237 164/18639 0.024390243902439 1.91818462488422 0.156709584348653 0.51153263655456 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 7/237 349/18639 0.0200573065902579 1.57741830183889 0.15790676034749 0.51153263655456 GO:0005496 steroid binding 3/237 108/18639 0.0277777777777778 2.18459915611814 0.158664265363241 0.51153263655456 GO:0019207 kinase regulator activity 6/237 287/18639 0.0209059233449477 1.64415824990076 0.160021513824799 0.51153263655456 GO:0016887 ATP hydrolysis activity 8/237 417/18639 0.0191846522781775 1.50878790638375 0.163250271377545 0.51153263655456 GO:0004601 peroxidase activity 2/237 57/18639 0.0350877192982456 2.75949367088608 0.163676817592237 0.51153263655456 GO:0005347 ATP transmembrane transporter activity 1/237 14/18639 0.0714285714285714 5.61754068716094 0.16407650606467 0.51153263655456 GO:0008191 metalloendopeptidase inhibitor activity 1/237 14/18639 0.0714285714285714 5.61754068716094 0.16407650606467 0.51153263655456 GO:0044548 S100 protein binding 1/237 14/18639 0.0714285714285714 5.61754068716094 0.16407650606467 0.51153263655456 GO:0140297 DNA-binding transcription factor binding 9/237 488/18639 0.0184426229508197 1.45043058725877 0.170713881834981 0.511591993937956 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/237 59/18639 0.0338983050847458 2.66595151255095 0.172706722422708 0.511591993937956 GO:0031593 polyubiquitin modification-dependent protein binding 2/237 59/18639 0.0338983050847458 2.66595151255095 0.172706722422708 0.511591993937956 GO:0004129 cytochrome-c oxidase activity 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0005523 tropomyosin binding 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0031386 protein tag activity 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0141047 molecular tag activity 1/237 15/18639 0.0666666666666667 5.24303797468354 0.174713492269377 0.511591993937956 GO:0005125 cytokine activity 5/237 234/18639 0.0213675213675214 1.68046088932165 0.178418332437208 0.5166542889337 GO:0035401 histone H3Y41 kinase activity 3/237 115/18639 0.0260869565217391 2.05162355531095 0.180455842499876 0.5166542889337 GO:0140801 histone H2AXY142 kinase activity 3/237 115/18639 0.0260869565217391 2.05162355531095 0.180455842499876 0.5166542889337 GO:0009055 electron transfer activity 3/237 116/18639 0.0258620689655172 2.03393714535137 0.183633542030704 0.5166542889337 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/237 16/18639 0.0625 4.91534810126582 0.185215688485666 0.5166542889337 GO:0004708 MAP kinase kinase activity 1/237 16/18639 0.0625 4.91534810126582 0.185215688485666 0.5166542889337 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/237 16/18639 0.0625 4.91534810126582 0.185215688485666 0.5166542889337 GO:0055102 lipase inhibitor activity 1/237 16/18639 0.0625 4.91534810126582 0.185215688485666 0.5166542889337 GO:0140327 flippase activity 1/237 16/18639 0.0625 4.91534810126582 0.185215688485666 0.5166542889337 GO:0022853 active monoatomic ion transmembrane transporter activity 3/237 118/18639 0.0254237288135593 1.99946363441322 0.190033231285498 0.527317343357664 GO:0004550 nucleoside diphosphate kinase activity 1/237 17/18639 0.0588235294117647 4.62620997766195 0.195584795602076 0.528877253413776 GO:0005092 GDP-dissociation inhibitor activity 1/237 17/18639 0.0588235294117647 4.62620997766195 0.195584795602076 0.528877253413776 GO:0008429 phosphatidylethanolamine binding 1/237 17/18639 0.0588235294117647 4.62620997766195 0.195584795602076 0.528877253413776 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/237 17/18639 0.0588235294117647 4.62620997766195 0.195584795602076 0.528877253413776 GO:0045236 CXCR chemokine receptor binding 1/237 17/18639 0.0588235294117647 4.62620997766195 0.195584795602076 0.528877253413776 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/237 181/18639 0.0220994475138122 1.73802363801664 0.199323909127645 0.536252141307877 GO:0032393 MHC class I receptor activity 1/237 18/18639 0.0555555555555556 4.36919831223629 0.205822493134151 0.54271602667214 GO:0034185 apolipoprotein binding 1/237 18/18639 0.0555555555555556 4.36919831223629 0.205822493134151 0.54271602667214 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/237 18/18639 0.0555555555555556 4.36919831223629 0.205822493134151 0.54271602667214 GO:0070064 proline-rich region binding 1/237 18/18639 0.0555555555555556 4.36919831223629 0.205822493134151 0.54271602667214 GO:0030145 manganese ion binding 2/237 68/18639 0.0294117647058824 2.31310498883098 0.214185416863678 0.552865376476785 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/237 19/18639 0.0526315789473684 4.13924050632911 0.215930439491876 0.552865376476785 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/237 19/18639 0.0526315789473684 4.13924050632911 0.215930439491876 0.552865376476785 GO:0030506 ankyrin binding 1/237 19/18639 0.0526315789473684 4.13924050632911 0.215930439491876 0.552865376476785 GO:0097001 ceramide binding 1/237 19/18639 0.0526315789473684 4.13924050632911 0.215930439491876 0.552865376476785 GO:0140036 ubiquitin-modified protein reader activity 1/237 19/18639 0.0526315789473684 4.13924050632911 0.215930439491876 0.552865376476785 GO:0140597 protein carrier chaperone 4/237 188/18639 0.0212765957446809 1.67330999192028 0.21780486574466 0.554983552137835 GO:0031490 chromatin DNA binding 3/237 128/18639 0.0234375 1.84325553797468 0.222811586744289 0.562124151592502 GO:0019902 phosphatase binding 4/237 190/18639 0.0210526315789474 1.65569620253165 0.22316944081339 0.562124151592502 GO:0000339 RNA cap binding 1/237 20/18639 0.05 3.93227848101266 0.225910272243779 0.562124151592502 GO:0016505 peptidase activator activity involved in apoptotic process 1/237 20/18639 0.05 3.93227848101266 0.225910272243779 0.562124151592502 GO:0030742 GTP-dependent protein binding 1/237 20/18639 0.05 3.93227848101266 0.225910272243779 0.562124151592502 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/237 21/18639 0.0476190476190476 3.74502712477396 0.23576360837774 0.5758281679272 GO:0010314 phosphatidylinositol-5-phosphate binding 1/237 21/18639 0.0476190476190476 3.74502712477396 0.23576360837774 0.5758281679272 GO:0036122 BMP binding 1/237 21/18639 0.0476190476190476 3.74502712477396 0.23576360837774 0.5758281679272 GO:0072542 protein phosphatase activator activity 1/237 21/18639 0.0476190476190476 3.74502712477396 0.23576360837774 0.5758281679272 GO:0051087 protein-folding chaperone binding 3/237 134/18639 0.0223880597014925 1.76072170791612 0.24298855186528 0.58629383359619 GO:0070034 telomerase RNA binding 1/237 22/18639 0.0454545454545455 3.57479861910242 0.245492044558558 0.58629383359619 GO:0140035 ubiquitin-like protein reader activity 1/237 22/18639 0.0454545454545455 3.57479861910242 0.245492044558558 0.58629383359619 GO:0140517 protein-RNA adaptor activity 1/237 22/18639 0.0454545454545455 3.57479861910242 0.245492044558558 0.58629383359619 GO:0003725 double-stranded RNA binding 2/237 75/18639 0.0266666666666667 2.09721518987342 0.247035345051814 0.58629383359619 GO:0019001 guanyl nucleotide binding 7/237 400/18639 0.0175 1.37629746835443 0.248124954368676 0.58629383359619 GO:0032561 guanyl ribonucleotide binding 7/237 400/18639 0.0175 1.37629746835443 0.248124954368676 0.58629383359619 GO:0051536 iron-sulfur cluster binding 2/237 76/18639 0.0263157894736842 2.06962025316456 0.251748170465504 0.58629383359619 GO:0000295 adenine nucleotide transmembrane transporter activity 1/237 23/18639 0.0434782608695652 3.41937259218492 0.255097157382302 0.58629383359619 GO:0005212 structural constituent of eye lens 1/237 23/18639 0.0434782608695652 3.41937259218492 0.255097157382302 0.58629383359619 GO:0017134 fibroblast growth factor binding 1/237 23/18639 0.0434782608695652 3.41937259218492 0.255097157382302 0.58629383359619 GO:0031681 G-protein beta-subunit binding 1/237 23/18639 0.0434782608695652 3.41937259218492 0.255097157382302 0.58629383359619 GO:0099186 structural constituent of postsynapse 1/237 23/18639 0.0434782608695652 3.41937259218492 0.255097157382302 0.58629383359619 GO:0051540 metal cluster binding 2/237 77/18639 0.025974025974026 2.04274206805852 0.256463375606801 0.58629383359619 GO:0140097 catalytic activity, acting on DNA 6/237 336/18639 0.0178571428571429 1.40438517179024 0.256844416945028 0.58629383359619 GO:0004175 endopeptidase activity 7/237 405/18639 0.0172839506172839 1.35930614158462 0.25774804382625 0.58629383359619 GO:0004713 protein tyrosine kinase activity 3/237 140/18639 0.0214285714285714 1.68526220614828 0.263447878659539 0.589191877825919 GO:0005540 hyaluronic acid binding 1/237 24/18639 0.0416666666666667 3.27689873417722 0.264580503627488 0.589191877825919 GO:0015295 solute:proton symporter activity 1/237 24/18639 0.0416666666666667 3.27689873417722 0.264580503627488 0.589191877825919 GO:0030215 semaphorin receptor binding 1/237 24/18639 0.0416666666666667 3.27689873417722 0.264580503627488 0.589191877825919 GO:0050431 transforming growth factor beta binding 1/237 24/18639 0.0416666666666667 3.27689873417722 0.264580503627488 0.589191877825919 GO:0016835 carbon-oxygen lyase activity 2/237 79/18639 0.0253164556962025 1.99102707899375 0.265897670085603 0.589647552909496 GO:0005516 calmodulin binding 4/237 207/18639 0.0193236714975845 1.51972115208219 0.270000272093842 0.592669613942403 GO:0020037 heme binding 3/237 142/18639 0.0211267605633803 1.66152611873774 0.27031692700948 0.592669613942403 GO:0000049 tRNA binding 2/237 80/18639 0.025 1.96613924050633 0.270615182215211 0.592669613942403 GO:0008139 nuclear localization sequence binding 1/237 25/18639 0.04 3.14582278481013 0.273943620503141 0.59504147076502 GO:0019211 phosphatase activator activity 1/237 25/18639 0.04 3.14582278481013 0.273943620503141 0.59504147076502 GO:0008094 ATP-dependent activity, acting on DNA 4/237 210/18639 0.019047619047619 1.49801084990958 0.278449996703672 0.595873330225456 GO:0005112 Notch binding 1/237 26/18639 0.0384615384615385 3.02482960077897 0.283188025893748 0.595873330225456 GO:0008157 protein phosphatase 1 binding 1/237 26/18639 0.0384615384615385 3.02482960077897 0.283188025893748 0.595873330225456 GO:0008198 ferrous iron binding 1/237 26/18639 0.0384615384615385 3.02482960077897 0.283188025893748 0.595873330225456 GO:0015216 purine nucleotide transmembrane transporter activity 1/237 26/18639 0.0384615384615385 3.02482960077897 0.283188025893748 0.595873330225456 GO:0019865 immunoglobulin binding 1/237 26/18639 0.0384615384615385 3.02482960077897 0.283188025893748 0.595873330225456 GO:0052742 phosphatidylinositol kinase activity 1/237 26/18639 0.0384615384615385 3.02482960077897 0.283188025893748 0.595873330225456 GO:0004860 protein kinase inhibitor activity 2/237 84/18639 0.0238095238095238 1.87251356238698 0.28947016990686 0.595873330225456 GO:0001671 ATPase activator activity 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0005104 fibroblast growth factor receptor binding 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0008266 poly(U) RNA binding 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0008320 protein transmembrane transporter activity 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0008395 steroid hydroxylase activity 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0015252 proton channel activity 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0023026 MHC class II protein complex binding 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0035255 ionotropic glutamate receptor binding 1/237 27/18639 0.037037037037037 2.91279887482419 0.292315218601167 0.595873330225456 GO:0045499 chemorepellent activity 1/237 28/18639 0.0357142857142857 2.80877034358047 0.301326678583518 0.59813909980998 GO:0046625 sphingolipid binding 1/237 28/18639 0.0357142857142857 2.80877034358047 0.301326678583518 0.59813909980998 GO:0046875 ephrin receptor binding 1/237 28/18639 0.0357142857142857 2.80877034358047 0.301326678583518 0.59813909980998 GO:0050698 proteoglycan sulfotransferase activity 1/237 28/18639 0.0357142857142857 2.80877034358047 0.301326678583518 0.59813909980998 GO:0051537 2 iron, 2 sulfur cluster binding 1/237 28/18639 0.0357142857142857 2.80877034358047 0.301326678583518 0.59813909980998 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/237 28/18639 0.0357142857142857 2.80877034358047 0.301326678583518 0.59813909980998 GO:0141052 histone H3 demethylase activity 1/237 28/18639 0.0357142857142857 2.80877034358047 0.301326678583518 0.59813909980998 GO:0140996 histone H3 kinase activity 6/237 357/18639 0.0168067226890756 1.32177427933199 0.302497616583617 0.598222898467601 GO:0046906 tetrapyrrole binding 3/237 152/18639 0.0197368421052632 1.55221518987342 0.304908932663887 0.600749941679777 GO:0035173 histone kinase activity 6/237 360/18639 0.0166666666666667 1.31075949367089 0.309148649958457 0.602266115792245 GO:0004629 phospholipase C activity 1/237 29/18639 0.0344827586206897 2.71191619380183 0.3102238671911 0.602266115792245 GO:0035250 UDP-galactosyltransferase activity 1/237 29/18639 0.0344827586206897 2.71191619380183 0.3102238671911 0.602266115792245 GO:0106222 lncRNA binding 1/237 29/18639 0.0344827586206897 2.71191619380183 0.3102238671911 0.602266115792245 GO:0019210 kinase inhibitor activity 2/237 90/18639 0.0222222222222222 1.74767932489451 0.317631592646893 0.603837001863073 GO:0008187 poly-pyrimidine tract binding 1/237 30/18639 0.0333333333333333 2.62151898734177 0.319008227399359 0.603837001863073 GO:0015215 nucleotide transmembrane transporter activity 1/237 30/18639 0.0333333333333333 2.62151898734177 0.319008227399359 0.603837001863073 GO:0031210 phosphatidylcholine binding 1/237 30/18639 0.0333333333333333 2.62151898734177 0.319008227399359 0.603837001863073 GO:0032452 histone demethylase activity 1/237 30/18639 0.0333333333333333 2.62151898734177 0.319008227399359 0.603837001863073 GO:0048019 receptor antagonist activity 1/237 30/18639 0.0333333333333333 2.62151898734177 0.319008227399359 0.603837001863073 GO:0098918 structural constituent of synapse 1/237 30/18639 0.0333333333333333 2.62151898734177 0.319008227399359 0.603837001863073 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/237 31/18639 0.032258064516129 2.53695385871784 0.327681184038961 0.611517702607921 GO:0017147 Wnt-protein binding 1/237 31/18639 0.032258064516129 2.53695385871784 0.327681184038961 0.611517702607921 GO:0070273 phosphatidylinositol-4-phosphate binding 1/237 31/18639 0.032258064516129 2.53695385871784 0.327681184038961 0.611517702607921 GO:0140457 protein demethylase activity 1/237 31/18639 0.032258064516129 2.53695385871784 0.327681184038961 0.611517702607921 GO:0099106 ion channel regulator activity 3/237 160/18639 0.01875 1.47460443037975 0.33272576490957 0.618753176849375 GO:0008378 galactosyltransferase activity 1/237 32/18639 0.03125 2.45767405063291 0.336244144022988 0.620938663178341 GO:0022884 macromolecule transmembrane transporter activity 1/237 32/18639 0.03125 2.45767405063291 0.336244144022988 0.620938663178341 GO:0140416 transcription regulator inhibitor activity 1/237 33/18639 0.0303030303030303 2.38319907940161 0.344698496571306 0.634340983273584 GO:0005525 GTP binding 6/237 378/18639 0.0158730158730159 1.24834237492465 0.34950788493061 0.638614932146867 GO:0008376 acetylgalactosaminyltransferase activity 1/237 34/18639 0.0294117647058824 2.31310498883098 0.353045613432136 0.638614932146867 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/237 34/18639 0.0294117647058824 2.31310498883098 0.353045613432136 0.638614932146867 GO:0030332 cyclin binding 1/237 34/18639 0.0294117647058824 2.31310498883098 0.353045613432136 0.638614932146867 GO:0051427 hormone receptor binding 1/237 34/18639 0.0294117647058824 2.31310498883098 0.353045613432136 0.638614932146867 GO:0042626 ATPase-coupled transmembrane transporter activity 2/237 98/18639 0.0204081632653061 1.60501162490313 0.354749588578678 0.639514564444555 GO:0016247 channel regulator activity 3/237 168/18639 0.0178571428571429 1.40438517179024 0.360507057556322 0.644720639809612 GO:0000175 3'-5'-RNA exonuclease activity 1/237 35/18639 0.0285714285714286 2.24701627486438 0.361286849100858 0.644720639809612 GO:0043015 gamma-tubulin binding 1/237 35/18639 0.0285714285714286 2.24701627486438 0.361286849100858 0.644720639809612 GO:0022804 active transmembrane transporter activity 7/237 457/18639 0.0153172866520788 1.20463673378944 0.362739731307883 0.644853464459175 GO:0043130 ubiquitin binding 2/237 100/18639 0.02 1.57291139240506 0.363923913082848 0.644853464459175 GO:0141108 transporter regulator activity 3/237 170/18639 0.0176470588235294 1.38786299329859 0.367430718286703 0.644853464459175 GO:0004190 aspartic-type endopeptidase activity 1/237 36/18639 0.0277777777777778 2.18459915611814 0.369423541036092 0.644853464459175 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/237 36/18639 0.0277777777777778 2.18459915611814 0.369423541036092 0.644853464459175 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/237 36/18639 0.0277777777777778 2.18459915611814 0.369423541036092 0.644853464459175 GO:0140098 catalytic activity, acting on RNA 6/237 387/18639 0.0155038759689922 1.21931115690315 0.369878213576583 0.644853464459175 GO:0051020 GTPase binding 5/237 315/18639 0.0158730158730159 1.24834237492465 0.372187649912648 0.646752309684274 GO:0023023 MHC protein complex binding 1/237 37/18639 0.027027027027027 2.12555593568252 0.377457009873078 0.650496613395641 GO:0070001 aspartic-type peptidase activity 1/237 37/18639 0.027027027027027 2.12555593568252 0.377457009873078 0.650496613395641 GO:0003823 antigen binding 3/237 174/18639 0.0172413793103448 1.35595809690092 0.381238110625759 0.650496613395641 GO:0033218 amide binding 4/237 247/18639 0.0161943319838057 1.27361246348588 0.384639003784572 0.650496613395641 GO:0000146 microfilament motor activity 1/237 38/18639 0.0263157894736842 2.06962025316456 0.385388559634399 0.650496613395641 GO:0005501 retinoid binding 1/237 38/18639 0.0263157894736842 2.06962025316456 0.385388559634399 0.650496613395641 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/237 38/18639 0.0263157894736842 2.06962025316456 0.385388559634399 0.650496613395641 GO:0019840 isoprenoid binding 1/237 38/18639 0.0263157894736842 2.06962025316456 0.385388559634399 0.650496613395641 GO:0043531 ADP binding 1/237 38/18639 0.0263157894736842 2.06962025316456 0.385388559634399 0.650496613395641 GO:0140104 molecular carrier activity 4/237 249/18639 0.0160642570281124 1.26338264450206 0.390390919496296 0.656020184438225 GO:0004497 monooxygenase activity 2/237 106/18639 0.0188679245283019 1.48387867208025 0.39113656279713 0.656020184438225 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/237 39/18639 0.0256410256410256 2.01655306718598 0.393219477938073 0.657433196552614 GO:0004532 RNA exonuclease activity 1/237 40/18639 0.025 1.96613924050633 0.400951036203056 0.659950463315588 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/237 40/18639 0.025 1.96613924050633 0.400951036203056 0.659950463315588 GO:0032451 demethylase activity 1/237 40/18639 0.025 1.96613924050633 0.400951036203056 0.659950463315588 GO:0050997 quaternary ammonium group binding 1/237 40/18639 0.025 1.96613924050633 0.400951036203056 0.659950463315588 GO:0071949 FAD binding 1/237 40/18639 0.025 1.96613924050633 0.400951036203056 0.659950463315588 GO:0019887 protein kinase regulator activity 4/237 255/18639 0.0156862745098039 1.23365599404319 0.407598785604793 0.662231741962232 GO:0001530 lipopolysaccharide binding 1/237 41/18639 0.024390243902439 1.91818462488422 0.40858448985217 0.662231741962232 GO:0001727 lipid kinase activity 1/237 41/18639 0.024390243902439 1.91818462488422 0.40858448985217 0.662231741962232 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/237 41/18639 0.024390243902439 1.91818462488422 0.40858448985217 0.662231741962232 GO:0140318 protein transporter activity 1/237 41/18639 0.024390243902439 1.91818462488422 0.40858448985217 0.662231741962232 GO:0003924 GTPase activity 5/237 331/18639 0.0151057401812689 1.18799954109144 0.412473088124641 0.664289673529009 GO:0004520 DNA endonuclease activity 1/237 42/18639 0.0238095238095238 1.87251356238698 0.416121078512511 0.664289673529009 GO:0031492 nucleosomal DNA binding 1/237 42/18639 0.0238095238095238 1.87251356238698 0.416121078512511 0.664289673529009 GO:0035198 miRNA binding 1/237 42/18639 0.0238095238095238 1.87251356238698 0.416121078512511 0.664289673529009 GO:0051879 Hsp90 protein binding 1/237 42/18639 0.0238095238095238 1.87251356238698 0.416121078512511 0.664289673529009 GO:0008200 ion channel inhibitor activity 1/237 43/18639 0.0232558139534884 1.82896673535472 0.423562026213352 0.672119382913403 GO:0048156 tau protein binding 1/237 43/18639 0.0232558139534884 1.82896673535472 0.423562026213352 0.672119382913403 GO:0003730 mRNA 3'-UTR binding 4/237 262/18639 0.0152671755725191 1.20069571939318 0.427553002370453 0.673740531239089 GO:0003954 NADH dehydrogenase activity 1/237 44/18639 0.0227272727272727 1.78739930955121 0.430908541581573 0.673740531239089 GO:0016248 channel inhibitor activity 1/237 44/18639 0.0227272727272727 1.78739930955121 0.430908541581573 0.673740531239089 GO:0019205 nucleobase-containing compound kinase activity 1/237 44/18639 0.0227272727272727 1.78739930955121 0.430908541581573 0.673740531239089 GO:0101005 deubiquitinase activity 2/237 115/18639 0.0173913043478261 1.36774903687397 0.430939698283115 0.673740531239089 GO:0141110 transporter inhibitor activity 1/237 45/18639 0.0222222222222222 1.74767932489451 0.438161818034661 0.680120810405108 GO:0030291 protein serine/threonine kinase inhibitor activity 1/237 46/18639 0.0217391304347826 1.70968629609246 0.445323033971295 0.680120810405108 GO:0005543 phospholipid binding 7/237 497/18639 0.0140845070422535 1.1076840791585 0.445858272742138 0.680120810405108 GO:0005504 fatty acid binding 1/237 47/18639 0.0212765957446809 1.67330999192028 0.45239335295956 0.680120810405108 GO:0032182 ubiquitin-like protein binding 2/237 120/18639 0.0166666666666667 1.31075949367089 0.45245281222998 0.680120810405108 GO:0005096 GTPase activator activity 4/237 271/18639 0.014760147601476 1.16082021579709 0.452948875460562 0.680120810405108 GO:0051082 unfolded protein binding 2/237 121/18639 0.0165289256198347 1.2999267705827 0.456700131380513 0.680120810405108 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/237 48/18639 0.0208333333333333 1.63844936708861 0.459373923922802 0.680120810405108 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/237 48/18639 0.0208333333333333 1.63844936708861 0.459373923922802 0.680120810405108 GO:0032266 phosphatidylinositol-3-phosphate binding 1/237 48/18639 0.0208333333333333 1.63844936708861 0.459373923922802 0.680120810405108 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/237 122/18639 0.0163934426229508 1.2892716331189 0.460928495701504 0.680120810405108 GO:0005004 GPI-linked ephrin receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0005008 hepatocyte growth factor receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0005009 insulin receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0005011 macrophage colony-stimulating factor receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0005020 stem cell factor receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0008288 boss receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0035254 glutamate receptor binding 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0036332 placental growth factor receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0038062 protein tyrosine kinase collagen receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0060175 brain-derived neurotrophic factor receptor activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0060590 ATPase regulator activity 1/237 49/18639 0.0204081632653061 1.60501162490313 0.466265881323173 0.680120810405108 GO:0141003 histone H2AX kinase activity 5/237 354/18639 0.0141242937853107 1.11081313022956 0.469627308899047 0.680120810405108 GO:0005006 epidermal growth factor receptor activity 1/237 50/18639 0.02 1.57291139240506 0.473070345342883 0.680120810405108 GO:0005007 fibroblast growth factor receptor activity 1/237 50/18639 0.02 1.57291139240506 0.473070345342883 0.680120810405108 GO:0005017 platelet-derived growth factor receptor activity 1/237 50/18639 0.02 1.57291139240506 0.473070345342883 0.680120810405108 GO:0005019 platelet-derived growth factor beta-receptor activity 1/237 50/18639 0.02 1.57291139240506 0.473070345342883 0.680120810405108 GO:0015605 organophosphate ester transmembrane transporter activity 1/237 50/18639 0.02 1.57291139240506 0.473070345342883 0.680120810405108 GO:0005010 insulin-like growth factor receptor activity 1/237 51/18639 0.0196078431372549 1.54206999255398 0.479788422063187 0.680120810405108 GO:0005021 vascular endothelial growth factor receptor activity 1/237 51/18639 0.0196078431372549 1.54206999255398 0.479788422063187 0.680120810405108 GO:0005030 neurotrophin receptor activity 1/237 51/18639 0.0196078431372549 1.54206999255398 0.479788422063187 0.680120810405108 GO:0005048 signal sequence binding 1/237 51/18639 0.0196078431372549 1.54206999255398 0.479788422063187 0.680120810405108 GO:0019783 ubiquitin-like protein peptidase activity 2/237 127/18639 0.015748031496063 1.23851290740556 0.481779075150257 0.680120810405108 GO:0030159 signaling receptor complex adaptor activity 1/237 52/18639 0.0192307692307692 1.51241480038948 0.486421203641142 0.680120810405108 GO:0005003 ephrin receptor activity 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0005005 transmembrane-ephrin receptor activity 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0005544 calcium-dependent phospholipid binding 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0008146 sulfotransferase activity 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0016860 intramolecular oxidoreductase activity 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0038064 collagen receptor activity 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0051018 protein kinase A binding 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0140296 general transcription initiation factor binding 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/237 53/18639 0.0188679245283019 1.48387867208025 0.492969768484153 0.680120810405108 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/237 130/18639 0.0153846153846154 1.20993184031159 0.494050022652767 0.680120810405108 GO:0031072 heat shock protein binding 2/237 131/18639 0.0152671755725191 1.20069571939318 0.4980994837146 0.682218160190318 GO:0050661 NADP binding 1/237 54/18639 0.0185185185185185 1.4563994374121 0.499435181422346 0.682218160190318 GO:0140463 chromatin-protein adaptor activity 1/237 54/18639 0.0185185185185185 1.4563994374121 0.499435181422346 0.682218160190318 GO:0170055 lipid transmembrane transporter activity 1/237 56/18639 0.0178571428571429 1.40438517179024 0.512120744037562 0.697748057429069 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/237 57/18639 0.0175438596491228 1.37974683544304 0.5183429570098 0.703740903414456 GO:0016922 nuclear receptor binding 2/237 137/18639 0.0145985401459854 1.14811050540516 0.52195798058987 0.703740903414456 GO:0001664 G protein-coupled receptor binding 4/237 297/18639 0.0134680134680135 1.05919959084516 0.523974152229395 0.703740903414456 GO:0008408 3'-5' exonuclease activity 1/237 58/18639 0.0172413793103448 1.35595809690092 0.524486144997566 0.703740903414456 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/237 58/18639 0.0172413793103448 1.35595809690092 0.524486144997566 0.703740903414456 GO:0061980 regulatory RNA binding 1/237 58/18639 0.0172413793103448 1.35595809690092 0.524486144997566 0.703740903414456 GO:0140767 enzyme-substrate adaptor activity 2/237 139/18639 0.0143884892086331 1.13159092978782 0.529741135529065 0.704742338224435 GO:0001786 phosphatidylserine binding 1/237 59/18639 0.0169491525423729 1.33297575627548 0.530551307455754 0.704742338224435 GO:0004879 nuclear receptor activity 1/237 59/18639 0.0169491525423729 1.33297575627548 0.530551307455754 0.704742338224435 GO:0036002 pre-mRNA binding 1/237 59/18639 0.0169491525423729 1.33297575627548 0.530551307455754 0.704742338224435 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/237 60/18639 0.0166666666666667 1.31075949367089 0.536539431251932 0.705622577080704 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/237 60/18639 0.0166666666666667 1.31075949367089 0.536539431251932 0.705622577080704 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/237 60/18639 0.0166666666666667 1.31075949367089 0.536539431251932 0.705622577080704 GO:0098531 ligand-modulated transcription factor activity 1/237 60/18639 0.0166666666666667 1.31075949367089 0.536539431251932 0.705622577080704 GO:0016836 hydro-lyase activity 1/237 61/18639 0.0163934426229508 1.2892716331189 0.542451490824206 0.709874790461307 GO:0019905 syntaxin binding 1/237 61/18639 0.0163934426229508 1.2892716331189 0.542451490824206 0.709874790461307 GO:0019955 cytokine binding 2/237 144/18639 0.0138888888888889 1.09229957805907 0.548820869415408 0.716441036428981 GO:0008194 UDP-glycosyltransferase activity 2/237 145/18639 0.0137931034482759 1.08476647752073 0.552571410952776 0.719564736621552 GO:0004536 DNA nuclease activity 1/237 64/18639 0.015625 1.22883702531646 0.559740845396731 0.727114333481048 GO:0019209 kinase activator activity 2/237 148/18639 0.0135135135135135 1.06277796784126 0.56369118037158 0.730455563806693 GO:0038024 cargo receptor activity 1/237 65/18639 0.0153846153846154 1.20993184031159 0.565358149280499 0.730828827118693 GO:0016500 protein-hormone receptor activity 1/237 67/18639 0.0149253731343284 1.17381447194408 0.576379540854902 0.741459118090044 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/237 67/18639 0.0149253731343284 1.17381447194408 0.576379540854902 0.741459118090044 GO:0140223 general transcription initiation factor activity 1/237 68/18639 0.0147058823529412 1.15655249441549 0.581785423302532 0.744797764131261 GO:1990841 promoter-specific chromatin binding 1/237 68/18639 0.0147058823529412 1.15655249441549 0.581785423302532 0.744797764131261 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/237 70/18639 0.0142857142857143 1.12350813743219 0.592391963928627 0.752920241923675 GO:0016782 transferase activity, transferring sulphur-containing groups 1/237 70/18639 0.0142857142857143 1.12350813743219 0.592391963928627 0.752920241923675 GO:0097110 scaffold protein binding 1/237 70/18639 0.0142857142857143 1.12350813743219 0.592391963928627 0.752920241923675 GO:0140299 molecular sensor activity 1/237 71/18639 0.0140845070422535 1.1076840791585 0.597594349870192 0.75771532399809 GO:0043539 protein serine/threonine kinase activator activity 1/237 73/18639 0.0136986301369863 1.07733657014045 0.607801591076034 0.767821035668965 GO:0035403 histone H3T6 kinase activity 3/237 247/18639 0.0121457489878543 0.955209347614411 0.61074988800183 0.767821035668965 GO:0003678 DNA helicase activity 1/237 74/18639 0.0135135135135135 1.06277796784126 0.612808109599948 0.767821035668965 GO:0003684 damaged DNA binding 1/237 74/18639 0.0135135135135135 1.06277796784126 0.612808109599948 0.767821035668965 GO:0031491 nucleosome binding 1/237 74/18639 0.0135135135135135 1.06277796784126 0.612808109599948 0.767821035668965 GO:0019003 GDP binding 1/237 75/18639 0.0133333333333333 1.04860759493671 0.617750984796544 0.77218873099568 GO:0098631 cell adhesion mediator activity 1/237 76/18639 0.0131578947368421 1.03481012658228 0.622631022320958 0.776457510188489 GO:0016874 ligase activity 2/237 167/18639 0.0119760479041916 0.941863109224589 0.62948126455433 0.78315744181642 GO:0019199 transmembrane receptor protein kinase activity 1/237 78/18639 0.0128205128205128 1.00827653359299 0.632205756321939 0.784705037120908 GO:0003713 transcription coactivator activity 3/237 256/18639 0.01171875 0.921627768987342 0.634886680508282 0.786191450162125 GO:0033293 monocarboxylic acid binding 1/237 79/18639 0.0126582278481013 0.995513539496875 0.63690201383779 0.786848641804262 GO:0001618 virus receptor activity 1/237 81/18639 0.0123456790123457 0.97093295827473 0.64611613897405 0.796375706177317 GO:0140030 modification-dependent protein binding 2/237 173/18639 0.0115606936416185 0.909197336650326 0.648594847614455 0.79757603070919 GO:0140272 exogenous protein binding 1/237 82/18639 0.0121951219512195 0.959092312442112 0.650635509329861 0.798233379501913 GO:0004527 exonuclease activity 1/237 84/18639 0.0119047619047619 0.93625678119349 0.659502551665675 0.805383300421216 GO:0051117 ATPase binding 1/237 84/18639 0.0119047619047619 0.93625678119349 0.659502551665675 0.805383300421216 GO:0045182 translation regulator activity 4/237 356/18639 0.0112359550561798 0.883658085620822 0.666267015006464 0.810336610788802 GO:0003779 actin binding 5/237 443/18639 0.0112866817155756 0.887647512643941 0.667318355947927 0.810336610788802 GO:0050660 flavin adenine dinucleotide binding 1/237 86/18639 0.0116279069767442 0.914483367677362 0.668145469650389 0.810336610788802 GO:0008081 phosphoric diester hydrolase activity 1/237 87/18639 0.0114942528735632 0.903972064600611 0.672384650574922 0.813616129691116 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/237 88/18639 0.0113636363636364 0.893699654775604 0.676569904877086 0.815354544787681 GO:0106310 protein serine kinase activity 4/237 361/18639 0.0110803324099723 0.871419053964024 0.676898112653924 0.815354544787681 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/237 89/18639 0.0112359550561798 0.883658085620822 0.680701915687508 0.816226278991808 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/237 89/18639 0.0112359550561798 0.883658085620822 0.680701915687508 0.816226278991808 GO:0140793 histone H2AXY142 phosphatase activity 1/237 90/18639 0.0111111111111111 0.873839662447257 0.684781357519425 0.819264378070643 GO:0072341 modified amino acid binding 1/237 91/18639 0.010989010989011 0.864237028793991 0.688808896376932 0.822226835765256 GO:0052689 carboxylic ester hydrolase activity 1/237 92/18639 0.0108695652173913 0.85484314804623 0.692785189861872 0.825114945228746 GO:0051213 dioxygenase activity 1/237 93/18639 0.010752688172043 0.845651286239281 0.696710887279391 0.827929978157124 GO:0016410 N-acyltransferase activity 1/237 94/18639 0.0106382978723404 0.83665499596014 0.700586629742175 0.829241789589906 GO:0031267 small GTPase binding 3/237 283/18639 0.0106007067137809 0.833698617882542 0.700944003275996 0.829241789589906 GO:0004725 protein tyrosine phosphatase activity 1/237 98/18639 0.0102040816326531 0.802505812451563 0.71560259129163 0.844697936268517 GO:0016758 hexosyltransferase activity 2/237 197/18639 0.0101522842639594 0.798432178885819 0.717304893360652 0.844825763291435 GO:0016829 lyase activity 2/237 200/18639 0.01 0.786455696202532 0.725052737191107 0.852057540379793 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/237 484/18639 0.0103305785123967 0.812454231614186 0.740391492105911 0.867748517269115 GO:0000149 SNARE binding 1/237 106/18639 0.00943396226415094 0.741939336040124 0.74342167460096 0.867748517269115 GO:0004518 nuclease activity 2/237 209/18639 0.00956937799043062 0.75258918296893 0.747229151796422 0.867748517269115 GO:0051015 actin filament binding 2/237 209/18639 0.00956937799043062 0.75258918296893 0.747229151796422 0.867748517269115 GO:0030695 GTPase regulator activity 5/237 489/18639 0.0102249488752556 0.804146928632445 0.748447016707416 0.867748517269115 GO:0004843 cysteine-type deubiquitinase activity 1/237 108/18639 0.00925925925925926 0.728199718706048 0.749942137520749 0.867748517269115 GO:0060589 nucleoside-triphosphatase regulator activity 5/237 490/18639 0.0102040816326531 0.802505812451563 0.750035875736335 0.867748517269115 GO:0001216 DNA-binding transcription activator activity 5/237 491/18639 0.010183299389002 0.800871381061641 0.751617334128011 0.867748517269115 GO:0004620 phospholipase activity 1/237 109/18639 0.00917431192660551 0.721518987341772 0.753140222535458 0.867748517269115 GO:1902936 phosphatidylinositol bisphosphate binding 1/237 111/18639 0.00900900900900901 0.708518645227506 0.759414715724325 0.873079825019289 GO:0017124 SH3 domain binding 1/237 115/18639 0.00869565217391304 0.683874518436984 0.771491232509971 0.884831749398106 GO:0015294 solute:monoatomic cation symporter activity 1/237 116/18639 0.00862068965517241 0.677979048450458 0.774414822333721 0.884831749398106 GO:0004540 RNA nuclease activity 1/237 121/18639 0.00826446280991736 0.649963385291348 0.788483396194522 0.884831749398106 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/237 122/18639 0.00819672131147541 0.644635816559452 0.791190461487852 0.884831749398106 GO:0000287 magnesium ion binding 2/237 230/18639 0.00869565217391304 0.683874518436984 0.793084172260434 0.884831749398106 GO:0005085 guanyl-nucleotide exchange factor activity 2/237 230/18639 0.00869565217391304 0.683874518436984 0.793084172260434 0.884831749398106 GO:0004674 protein serine/threonine kinase activity 4/237 433/18639 0.0092378752886836 0.726517964159383 0.804066630092103 0.884831749398106 GO:0004519 endonuclease activity 1/237 127/18639 0.0078740157480315 0.619256453702781 0.804216938035061 0.884831749398106 GO:0016298 lipase activity 1/237 130/18639 0.00769230769230769 0.604965920155794 0.811641017540371 0.884831749398106 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/237 132/18639 0.00757575757575758 0.595799769850403 0.816433979259258 0.884831749398106 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/237 243/18639 0.00823045267489712 0.64728863884982 0.817661278067416 0.884831749398106 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0004711 ribosomal protein S6 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0035175 histone H3S10 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0035979 histone H2AXS139 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0044022 histone H3S28 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0044023 histone H4S1 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0044024 histone H2AS1 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0044025 histone H2BS14 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0072354 histone H3T3 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0072371 histone H2AS121 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0140823 histone H2BS36 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0140855 histone H3S57 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0140995 histone H2A kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0140997 histone H4 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0140998 histone H2B kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:1990244 histone H2AT120 kinase activity 2/237 245/18639 0.00816326530612245 0.64200464996125 0.821202618783658 0.884831749398106 GO:0004677 DNA-dependent protein kinase activity 2/237 246/18639 0.00813008130081301 0.639394874961408 0.822950151708452 0.884831749398106 GO:0140857 histone H3T45 kinase activity 2/237 246/18639 0.00813008130081301 0.639394874961408 0.822950151708452 0.884831749398106 GO:0015297 antiporter activity 1/237 135/18639 0.00740740740740741 0.582559774964838 0.823396645949708 0.884831749398106 GO:0035402 histone H3T11 kinase activity 2/237 247/18639 0.00809716599190283 0.636806231742941 0.824682398759119 0.884831749398106 GO:0140789 histone phosphatase activity 1/237 136/18639 0.00735294117647059 0.578276247207744 0.825658589038225 0.884831749398106 GO:0004679 AMP-activated protein kinase activity 2/237 248/18639 0.00806451612903226 0.634238464679461 0.826399464060496 0.884831749398106 GO:0030295 protein kinase activator activity 1/237 139/18639 0.00719424460431655 0.565795464893908 0.832272777145758 0.887534349873746 GO:0070851 growth factor receptor binding 1/237 139/18639 0.00719424460431655 0.565795464893908 0.832272777145758 0.887534349873746 GO:0042578 phosphoric ester hydrolase activity 3/237 363/18639 0.00826446280991736 0.649963385291348 0.843466519722405 0.897665171592118 GO:0015293 symporter activity 1/237 146/18639 0.00684931506849315 0.538668285070227 0.846750208541585 0.899353928911904 GO:0046982 protein heterodimerization activity 3/237 369/18639 0.00813008130081301 0.639394874961408 0.851313606935111 0.902392423351218 GO:0016757 glycosyltransferase activity 2/237 267/18639 0.00749063670411985 0.589105390413881 0.85627614674012 0.904347025410891 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/237 268/18639 0.00746268656716418 0.586907235972039 0.857711106090694 0.904347025410891 GO:0008514 organic anion transmembrane transporter activity 2/237 269/18639 0.00743494423791822 0.584725424685897 0.859133015215416 0.904347025410891 GO:0003774 cytoskeletal motor activity 1/237 153/18639 0.0065359477124183 0.514023330851328 0.859982831711489 0.904347025410891 GO:0016791 phosphatase activity 2/237 273/18639 0.00732600732600733 0.576158019195994 0.864692105322435 0.906341524756425 GO:0140375 immune receptor activity 1/237 156/18639 0.00641025641025641 0.504138266796495 0.865299644390096 0.906341524756425 GO:0008017 microtubule binding 2/237 276/18639 0.0072463768115942 0.56989543203082 0.868729163339735 0.90730897193701 GO:0015631 tubulin binding 3/237 385/18639 0.00779220779220779 0.612822620417557 0.87059101603852 0.90730897193701 GO:0001217 DNA-binding transcription repressor activity 2/237 278/18639 0.00719424460431655 0.565795464893908 0.871358993803657 0.90730897193701 GO:0003712 transcription coregulator activity 4/237 495/18639 0.00808080808080808 0.635519754507096 0.878146599952971 0.911799042159945 GO:0016755 aminoacyltransferase activity 4/237 496/18639 0.00806451612903226 0.634238464679461 0.879111906686286 0.911799042159945 GO:0015291 secondary active transmembrane transporter activity 2/237 287/18639 0.00696864111498258 0.548052749966921 0.882605701985023 0.913634808695434 GO:0004721 phosphoprotein phosphatase activity 1/237 175/18639 0.00571428571428571 0.449403254972875 0.894603679292152 0.924249415253101 GO:0016853 isomerase activity 1/237 180/18639 0.00555555555555556 0.436919831223629 0.901197165970396 0.927802423609456 GO:0008237 metallopeptidase activity 1/237 184/18639 0.00543478260869565 0.427421574023115 0.906174895747249 0.927802423609456 GO:1901981 phosphatidylinositol phosphate binding 1/237 185/18639 0.00540540540540541 0.425111187136504 0.907379802260817 0.927802423609456 GO:0008234 cysteine-type peptidase activity 1/237 187/18639 0.0053475935828877 0.420564543423814 0.909743584481777 0.927802423609456 GO:0031406 carboxylic acid binding 1/237 187/18639 0.0053475935828877 0.420564543423814 0.909743584481777 0.927802423609456 GO:0046943 carboxylic acid transmembrane transporter activity 1/237 188/18639 0.00531914893617021 0.41832749798007 0.910902850169931 0.927802423609456 GO:0005342 organic acid transmembrane transporter activity 1/237 189/18639 0.00529100529100529 0.416114124974884 0.912047288114201 0.927802423609456 GO:0043177 organic acid binding 1/237 189/18639 0.00529100529100529 0.416114124974884 0.912047288114201 0.927802423609456 GO:0004842 ubiquitin-protein transferase activity 3/237 449/18639 0.0066815144766147 0.525471511939331 0.927396601550298 0.941609576286701 GO:0061630 ubiquitin protein ligase activity 2/237 353/18639 0.0056657223796034 0.445583963854126 0.941091146728322 0.953687012936923 GO:0019787 ubiquitin-like protein transferase activity 3/237 479/18639 0.00626304801670146 0.492560978832483 0.945230608141319 0.956053859379578 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/237 229/18639 0.00436681222707424 0.34343043502294 0.94758994003157 0.956614606127109 GO:0061659 ubiquitin-like protein ligase activity 2/237 372/18639 0.00537634408602151 0.422825643119641 0.951952045578591 0.959191224632421 GO:0042393 histone binding 1/237 247/18639 0.00404858299595142 0.31840311587147 0.958497081059659 0.963953421179543 GO:0035091 phosphatidylinositol binding 1/237 284/18639 0.00352112676056338 0.276921019789624 0.974327805979988 0.9780184416087 GO:0005261 monoatomic cation channel activity 1/237 341/18639 0.00293255131964809 0.230632168974349 0.987774901057528 0.989642150397901 GO:0005216 monoatomic ion channel activity 1/237 448/18639 0.00223214285714286 0.175548146473779 0.996982388350283 0.996982388350283