ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 79/1459 175/18639 0.451428571428571 5.76708508763341 4.48834777021003e-41 5.20648341344364e-38 GO:0045296 cadherin binding 77/1459 334/18639 0.230538922155689 2.9451781837285 2.89182430441689e-18 1.6772580965618e-15 GO:0005201 extracellular matrix structural constituent 47/1459 168/18639 0.279761904761905 3.57401106432978 5.22883074284915e-15 2.02181455390167e-12 GO:0019838 growth factor binding 34/1459 136/18639 0.25 3.19379712131597 8.28089256754685e-10 2.40145884458859e-07 GO:0019843 rRNA binding 22/1459 65/18639 0.338461538461538 4.32390994885854 1.7858767029363e-09 4.14323395081221e-07 GO:0008135 translation factor activity, RNA binding 25/1459 83/18639 0.301204819277108 3.8479483389349 2.28207674663812e-09 4.41201504350036e-07 GO:0180051 translation factor activity 25/1459 84/18639 0.297619047619048 3.80213943013806 3.00963195513756e-09 4.9873900970851e-07 GO:0044389 ubiquitin-like protein ligase binding 57/1459 322/18639 0.177018633540373 2.26144640888212 4.46508845092608e-09 6.47437825384282e-07 GO:0031625 ubiquitin protein ligase binding 54/1459 302/18639 0.178807947019868 2.28430522584189 7.91527902059127e-09 1.02019151820954e-06 GO:0005178 integrin binding 35/1459 161/18639 0.217391304347826 2.77721488810084 2.38914341035931e-08 2.65520168653052e-06 GO:0003743 translation initiation factor activity 18/1459 51/18639 0.352941176470588 4.50889005362255 2.5178636682617e-08 2.65520168653052e-06 GO:0005539 glycosaminoglycan binding 45/1459 242/18639 0.18595041322314 2.37555157783832 4.16600349514063e-08 4.02713671196928e-06 GO:0002020 protease binding 30/1459 136/18639 0.220588235294118 2.81805628351409 1.67439211762685e-07 1.4940729664978e-05 GO:0003779 actin binding 65/1459 443/18639 0.146726862302483 1.87446332176558 6.15822357218137e-07 5.10252810266456e-05 GO:0008201 heparin binding 33/1459 172/18639 0.191860465116279 2.45105360473086 1.25069943685456e-06 9.67207564500859e-05 GO:0140297 DNA-binding transcription factor binding 68/1459 488/18639 0.139344262295082 1.78014921515972 2.23699470388157e-06 0.000162182116031414 GO:0030020 extracellular matrix structural constituent conferring tensile strength 14/1459 44/18639 0.318181818181818 4.06483269985669 3.73121416428692e-06 0.000254600495916049 GO:1901681 sulfur compound binding 44/1459 275/18639 0.16 2.04403015764222 4.25830278007134e-06 0.000270023532000508 GO:0048407 platelet-derived growth factor binding 7/1459 11/18639 0.636363636363636 8.12966539971338 4.42279923104281e-06 0.000270023532000508 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 52/1459 349/18639 0.148997134670487 1.90346647917972 5.14003252610553e-06 0.000298121886514121 GO:0051015 actin filament binding 36/1459 209/18639 0.172248803827751 2.20051093526076 5.79778501441726e-06 0.000320258600796382 GO:0051082 unfolded protein binding 25/1459 121/18639 0.206611570247934 2.63950175315369 6.09713393080299e-06 0.000321485243624158 GO:0046332 SMAD binding 19/1459 79/18639 0.240506329113924 3.07251368632929 7.9571440998949e-06 0.000401316832864265 GO:0019207 kinase regulator activity 44/1459 287/18639 0.153310104529617 1.95856548206136 1.29900539631634e-05 0.000627852608219564 GO:0051020 GTPase binding 47/1459 315/18639 0.149206349206349 1.90613923430921 1.38540135523991e-05 0.000642826228831316 GO:0019209 kinase activator activity 27/1459 148/18639 0.182432432432432 2.33060871014949 2.90049334395043e-05 0.00129406626114711 GO:0005522 profilin binding 6/1459 10/18639 0.6 7.66511309115833 3.63070699537866e-05 0.00155985930171824 GO:0048027 mRNA 5'-UTR binding 9/1459 24/18639 0.375 4.79069568197396 4.77226846554059e-05 0.00197708265000967 GO:0097493 structural molecule activity conferring elasticity 6/1459 11/18639 0.545454545454545 6.96828462832575 7.4568194821079e-05 0.00288330353308172 GO:1990948 ubiquitin ligase inhibitor activity 6/1459 11/18639 0.545454545454545 6.96828462832575 7.4568194821079e-05 0.00288330353308172 GO:0005518 collagen binding 16/1459 72/18639 0.222222222222222 2.83893077450308 0.000112735970848684 0.00421850729627335 GO:0003712 transcription coregulator activity 62/1459 495/18639 0.125252525252525 1.60012461835628 0.000154413465666546 0.0055974881304123 GO:0140996 histone H3 kinase activity 48/1459 357/18639 0.134453781512605 1.71767240138002 0.000161209947417753 0.0056667739092301 GO:0051019 mitogen-activated protein kinase binding 9/1459 28/18639 0.321428571428571 4.1063105845491 0.00018927717676773 0.0061715218401074 GO:0031267 small GTPase binding 40/1459 283/18639 0.141342756183746 1.80568035127405 0.000193668875618896 0.0061715218401074 GO:0019887 protein kinase regulator activity 37/1459 255/18639 0.145098039215686 1.8536547998226 0.000195151988829588 0.0061715218401074 GO:0035173 histone kinase activity 48/1459 360/18639 0.133333333333333 1.70335846470185 0.000196850265589632 0.0061715218401074 GO:0141003 histone H2AX kinase activity 47/1459 354/18639 0.132768361581921 1.69614084408871 0.000251892363070435 0.00768934582004486 GO:0098641 cadherin binding involved in cell-cell adhesion 7/1459 18/18639 0.388888888888889 4.9681288553804 0.000261242819947648 0.00777029925998131 GO:0035198 miRNA binding 11/1459 42/18639 0.261904761904762 3.34588269852149 0.000288113296204735 0.00835528558993731 GO:0001968 fibronectin binding 9/1459 30/18639 0.3 3.83255654557916 0.000339865483046689 0.00961570634961365 GO:0016504 peptidase activator activity 13/1459 57/18639 0.228070175438596 2.91363947909527 0.000369729384605401 0.0102115734795777 GO:0005161 platelet-derived growth factor receptor binding 6/1459 14/18639 0.428571428571429 5.47508077939881 0.000394615038984813 0.0106454289586601 GO:0004674 protein serine/threonine kinase activity 54/1459 433/18639 0.124711316397229 1.59321057321998 0.000444318506386898 0.0116458839883927 GO:0043539 protein serine/threonine kinase activator activity 15/1459 73/18639 0.205479452054795 2.62503872984874 0.000451779982308339 0.0116458839883927 GO:0030295 protein kinase activator activity 23/1459 139/18639 0.165467625899281 2.11388010907244 0.000483660964779343 0.0121966678074791 GO:0031072 heat shock protein binding 22/1459 131/18639 0.16793893129771 2.14545150134203 0.00051559378061916 0.0127252933088984 GO:0043024 ribosomal small subunit binding 7/1459 20/18639 0.35 4.47131596984236 0.000553645599574601 0.0133797686563862 GO:0050840 extracellular matrix binding 14/1459 67/18639 0.208955223880597 2.66944237005514 0.000579414028624507 0.0137167402694781 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/1459 15/18639 0.4 5.11007539410555 0.000614265185121812 0.0141527162204295 GO:0043021 ribonucleoprotein complex binding 27/1459 177/18639 0.152542372881356 1.94875756554873 0.000622231489001642 0.0141527162204295 GO:0001846 opsonin binding 7/1459 21/18639 0.333333333333333 4.25839616175463 0.000774727833682817 0.0172763831227372 GO:0003925 G protein activity 12/1459 54/18639 0.222222222222222 2.83893077450308 0.000789351987504374 0.0172763831227372 GO:0097110 scaffold protein binding 14/1459 70/18639 0.2 2.55503769705278 0.000917798788191156 0.0196215128357854 GO:0004857 enzyme inhibitor activity 51/1459 416/18639 0.122596153846154 1.56618897295302 0.000930330349972585 0.0196215128357854 GO:0016922 nuclear receptor binding 22/1459 137/18639 0.160583941605839 2.05149012172121 0.000959399017233933 0.019855887959962 GO:0030695 GTPase regulator activity 58/1459 489/18639 0.118609406952965 1.5152575299495 0.000975677253205029 0.019855887959962 GO:0060589 nucleoside-triphosphatase regulator activity 58/1459 490/18639 0.118367346938776 1.51216516764348 0.00102463786724094 0.0204258324798882 GO:0097718 disordered domain specific binding 8/1459 28/18639 0.285714285714286 3.65005385293254 0.00103890010027018 0.0204258324798882 GO:0003785 actin monomer binding 8/1459 29/18639 0.275862068965517 3.52418992696935 0.00133733148093961 0.0258550752981657 GO:0005543 phospholipid binding 58/1459 497/18639 0.116700201207243 1.49086706669075 0.00143280194881397 0.0272467255840034 GO:0055106 ubiquitin-protein transferase regulator activity 9/1459 36/18639 0.25 3.19379712131597 0.00145909233293254 0.0272991468742217 GO:0061134 peptidase regulator activity 31/1459 226/18639 0.13716814159292 1.75234886302292 0.00157875199907511 0.0290690844274147 GO:0043394 proteoglycan binding 9/1459 37/18639 0.243243243243243 3.10747828019932 0.00179608007222186 0.0324314044495359 GO:0003746 translation elongation factor activity 6/1459 18/18639 0.333333333333333 4.25839616175463 0.00185749292410242 0.0324314044495359 GO:0008525 phosphatidylcholine transporter activity 6/1459 18/18639 0.333333333333333 4.25839616175463 0.00185749292410242 0.0324314044495359 GO:0050431 transforming growth factor beta binding 7/1459 24/18639 0.291666666666667 3.7260966415353 0.00187319318803354 0.0324314044495359 GO:0004715 non-membrane spanning protein tyrosine kinase activity 10/1459 45/18639 0.222222222222222 2.83893077450308 0.00211921866431821 0.0361513772148401 GO:0031994 insulin-like growth factor I binding 5/1459 13/18639 0.384615384615385 4.9135340327938 0.00220336212810912 0.0370420299798055 GO:0005096 GTPase activator activity 35/1459 271/18639 0.129151291512915 1.64993209219275 0.00234580066064466 0.0388732680906829 GO:0005520 insulin-like growth factor binding 6/1459 19/18639 0.315789473684211 4.03427004797807 0.00253673650239811 0.0414452724335466 GO:0004713 protein tyrosine kinase activity 21/1459 140/18639 0.15 1.91627827278958 0.00292461963773647 0.0471188719413098 GO:0001784 phosphotyrosine residue binding 10/1459 47/18639 0.212765957446809 2.71812520963061 0.00298207059075641 0.0473863271955813 GO:0008143 poly(A) binding 7/1459 26/18639 0.269230769230769 3.43947382295566 0.00310104405024292 0.0486109607875917 GO:0140313 molecular sequestering activity 11/1459 55/18639 0.2 2.55503769705278 0.0031498628997206 0.0486142946855138 GO:0140662 ATP-dependent protein folding chaperone 9/1459 40/18639 0.225 2.87441740918437 0.00319260831165733 0.0486142946855138 GO:0140311 protein sequestering activity 8/1459 33/18639 0.242424242424242 3.097015390367 0.00326889222885352 0.0486142946855138 GO:0140416 transcription regulator inhibitor activity 8/1459 33/18639 0.242424242424242 3.097015390367 0.00326889222885352 0.0486142946855138 GO:0019001 guanyl nucleotide binding 47/1459 400/18639 0.1175 1.50108464701851 0.00337540516645605 0.0489433749136127 GO:0032561 guanyl ribonucleotide binding 47/1459 400/18639 0.1175 1.50108464701851 0.00337540516645605 0.0489433749136127 GO:0035401 histone H3Y41 kinase activity 18/1459 115/18639 0.156521739130435 1.99959471943261 0.0035474197858782 0.0501830116051062 GO:0140801 histone H2AXY142 kinase activity 18/1459 115/18639 0.156521739130435 1.99959471943261 0.0035474197858782 0.0501830116051062 GO:0106310 protein serine kinase activity 43/1459 361/18639 0.119113573407202 1.52169835143032 0.00383327332266763 0.0535734584854754 GO:0003924 GTPase activity 40/1459 331/18639 0.120845921450151 1.54382942420107 0.00402520273615228 0.0555861330230553 GO:0019955 cytokine binding 21/1459 144/18639 0.145833333333333 1.86304832076765 0.00410665309164522 0.0560437363095112 GO:0038024 cargo receptor activity 12/1459 65/18639 0.184615384615385 2.35849633574102 0.00417657949043824 0.0563352582431204 GO:0019208 phosphatase regulator activity 18/1459 117/18639 0.153846153846154 1.96541361311752 0.00427983218002537 0.0570644290670049 GO:0061980 regulatory RNA binding 11/1459 58/18639 0.189655172413793 2.42288057479143 0.00483325449281823 0.063396505947845 GO:0046875 ephrin receptor binding 7/1459 28/18639 0.25 3.19379712131597 0.00486404226668811 0.063396505947845 GO:0019003 GDP binding 13/1459 75/18639 0.173333333333333 2.21436600411241 0.00514524873093163 0.0663165391986743 GO:0005525 GTP binding 44/1459 378/18639 0.116402116402116 1.48705897712066 0.00528210783528055 0.0667138274890422 GO:0030957 Tat protein binding 4/1459 10/18639 0.4 5.11007539410555 0.00534860858317321 0.0667138274890422 GO:0042975 peroxisome proliferator activated receptor binding 4/1459 10/18639 0.4 5.11007539410555 0.00534860858317321 0.0667138274890422 GO:0045309 protein phosphorylated amino acid binding 11/1459 59/18639 0.186440677966102 2.38181480233733 0.00553026961045068 0.0681030591949083 GO:0051219 phosphoprotein binding 15/1459 93/18639 0.161290322580645 2.06051427181675 0.00557740570992783 0.0681030591949083 GO:0005548 phospholipid transporter activity 12/1459 68/18639 0.176470588235294 2.25444502681127 0.00608242848582914 0.071174457217859 GO:1990841 promoter-specific chromatin binding 12/1459 68/18639 0.176470588235294 2.25444502681127 0.00608242848582914 0.071174457217859 GO:0005516 calmodulin binding 27/1459 207/18639 0.130434782608696 1.66632893286051 0.00608726184530449 0.071174457217859 GO:0035403 histone H3T6 kinase activity 31/1459 247/18639 0.125506072874494 1.60336373701692 0.00612734760443609 0.071174457217859 GO:0140328 floppase activity 5/1459 16/18639 0.3125 3.99224640164496 0.00613572907050509 0.071174457217859 GO:0005080 protein kinase C binding 10/1459 52/18639 0.192307692307692 2.4567670163969 0.00638343386143444 0.0733146859333064 GO:0017134 fibroblast growth factor binding 6/1459 23/18639 0.260869565217391 3.33265786572101 0.00720400569659576 0.0819279079220694 GO:0015215 nucleotide transmembrane transporter activity 7/1459 30/18639 0.233333333333333 2.98087731322824 0.00729065220765738 0.0821083161250734 GO:0140031 phosphorylation-dependent protein binding 4/1459 11/18639 0.363636363636364 4.6455230855505 0.00788887486550968 0.0860527552631158 GO:0001221 transcription coregulator binding 17/1459 115/18639 0.147826086956522 1.88850612390857 0.00806956264283698 0.0860527552631158 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 5/1459 17/18639 0.294117647058824 3.75740837801879 0.00814002886819435 0.0860527552631158 GO:0019198 transmembrane receptor protein phosphatase activity 5/1459 17/18639 0.294117647058824 3.75740837801879 0.00814002886819435 0.0860527552631158 GO:0004180 carboxypeptidase activity 9/1459 46/18639 0.195652173913043 2.49949339929076 0.00843051489609537 0.0860527552631158 GO:0019903 protein phosphatase binding 20/1459 144/18639 0.138888888888889 1.77433173406443 0.00861392304276646 0.0860527552631158 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 30/1459 243/18639 0.123456790123457 1.57718376361282 0.0086954000857193 0.0860527552631158 GO:0035091 phosphatidylinositol binding 34/1459 284/18639 0.119718309859155 1.52942397358793 0.00869649529957165 0.0860527552631158 GO:0019888 protein phosphatase regulator activity 16/1459 107/18639 0.149532710280374 1.91030855854413 0.00895885072747292 0.0860527552631158 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 14/1459 89/18639 0.157303370786517 2.0095802111651 0.00905345568846692 0.0860527552631158 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 14/1459 89/18639 0.157303370786517 2.0095802111651 0.00905345568846692 0.0860527552631158 GO:0004676 3-phosphoinositide-dependent protein kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0004711 ribosomal protein S6 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0035175 histone H3S10 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0035979 histone H2AXS139 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0044022 histone H3S28 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0044023 histone H4S1 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0044024 histone H2AS1 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0044025 histone H2BS14 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0072354 histone H3T3 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0072371 histone H2AS121 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0072518 Rho-dependent protein serine/threonine kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0140823 histone H2BS36 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0140855 histone H3S57 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0140995 histone H2A kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0140997 histone H4 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0140998 histone H2B kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:1990244 histone H2AT120 kinase activity 30/1459 245/18639 0.122448979591837 1.56430879411394 0.00971802667195532 0.0860527552631158 GO:0140793 histone H2AXY142 phosphatase activity 14/1459 90/18639 0.155555555555556 1.98725154215216 0.00997101028269037 0.087624029756976 GO:0003713 transcription coactivator activity 31/1459 256/18639 0.12109375 1.54699548063742 0.0101274587732426 0.088096482461596 GO:0004677 DNA-dependent protein kinase activity 30/1459 246/18639 0.121951219512195 1.55794981527608 0.0102651426961458 0.088096482461596 GO:0140857 histone H3T45 kinase activity 30/1459 246/18639 0.121951219512195 1.55794981527608 0.0102651426961458 0.088096482461596 GO:0051059 NF-kappaB binding 7/1459 32/18639 0.21875 2.79457248115147 0.0105127233069091 0.088096482461596 GO:0070717 poly-purine tract binding 7/1459 32/18639 0.21875 2.79457248115147 0.0105127233069091 0.088096482461596 GO:0034185 apolipoprotein binding 5/1459 18/18639 0.277777777777778 3.54866346812886 0.0105563888466912 0.088096482461596 GO:0070064 proline-rich region binding 5/1459 18/18639 0.277777777777778 3.54866346812886 0.0105563888466912 0.088096482461596 GO:0035402 histone H3T11 kinase activity 30/1459 247/18639 0.121457489878543 1.55164232614541 0.0108371881005296 0.0897938442615314 GO:0001848 complement binding 6/1459 25/18639 0.24 3.06604523646333 0.0110502965341278 0.0902625067839547 GO:0061791 GTPase motor activity 8/1459 40/18639 0.2 2.55503769705278 0.0111271883362979 0.0902625067839547 GO:1990606 membrane scission GTPase motor activity 8/1459 40/18639 0.2 2.55503769705278 0.0111271883362979 0.0902625067839547 GO:0004679 AMP-activated protein kinase activity 30/1459 248/18639 0.120967741935484 1.54538570386257 0.0114349726204389 0.0921150572202021 GO:0071889 14-3-3 protein binding 7/1459 33/18639 0.212121212121212 2.70988846657113 0.0124629855202318 0.099703884161854 GO:0001530 lipopolysaccharide binding 8/1459 41/18639 0.195121951219512 2.49271970444173 0.0129006584415663 0.102498382138472 GO:0044183 protein folding chaperone 12/1459 75/18639 0.16 2.04403015764222 0.0132005477540259 0.104167587718844 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 4/1459 13/18639 0.307692307692308 3.93082722623504 0.0150669449009344 0.116517707233893 GO:0140666 annealing activity 4/1459 13/18639 0.307692307692308 3.93082722623504 0.0150669449009344 0.116517707233893 GO:0140852 histone ubiquitin ligase activity 4/1459 13/18639 0.307692307692308 3.93082722623504 0.0150669449009344 0.116517707233893 GO:0070063 RNA polymerase binding 10/1459 59/18639 0.169491525423729 2.16528618394303 0.0154531512138291 0.118712949722131 GO:0016209 antioxidant activity 13/1459 86/18639 0.151162790697674 1.93113314312128 0.0159889156873391 0.122020672350746 GO:0023026 MHC class II protein complex binding 6/1459 27/18639 0.222222222222222 2.83893077450308 0.0161571624376388 0.122498747893209 GO:0051087 protein-folding chaperone binding 18/1459 134/18639 0.134328358208955 1.71607009503545 0.016896538282498 0.127272626024011 GO:0048156 tau protein binding 8/1459 43/18639 0.186046511627907 2.37677925307235 0.0170538865865251 0.127629086712059 GO:0046966 nuclear thyroid hormone receptor binding 6/1459 28/18639 0.214285714285714 2.7375403896994 0.0192371043024435 0.142360632324767 GO:0015026 coreceptor activity 10/1459 61/18639 0.163934426229508 2.09429319430555 0.019267775237059 0.142360632324767 GO:0005347 ATP transmembrane transporter activity 4/1459 14/18639 0.285714285714286 3.65005385293254 0.0198104342124813 0.14362564804049 GO:0019992 diacylglycerol binding 4/1459 14/18639 0.285714285714286 3.65005385293254 0.0198104342124813 0.14362564804049 GO:0042043 neurexin family protein binding 4/1459 14/18639 0.285714285714286 3.65005385293254 0.0198104342124813 0.14362564804049 GO:0004725 protein tyrosine phosphatase activity 14/1459 98/18639 0.142857142857143 1.82502692646627 0.0201834068255661 0.145420819364327 GO:0042826 histone deacetylase binding 17/1459 127/18639 0.133858267716535 1.71006460038965 0.0204882057322596 0.145519189588676 GO:0070182 DNA polymerase binding 5/1459 21/18639 0.238095238095238 3.04171154411045 0.0206195006479461 0.145519189588676 GO:0004864 protein phosphatase inhibitor activity 9/1459 53/18639 0.169811320754717 2.16937162957311 0.0207923097083217 0.145519189588676 GO:0140296 general transcription initiation factor binding 9/1459 53/18639 0.169811320754717 2.16937162957311 0.0207923097083217 0.145519189588676 GO:0003727 single-stranded RNA binding 13/1459 89/18639 0.146067415730337 1.86603876751045 0.0208242978204484 0.145519189588676 GO:0043236 laminin binding 6/1459 29/18639 0.206896551724138 2.64314244522701 0.0226938678117682 0.157634051866174 GO:0001618 virus receptor activity 12/1459 81/18639 0.148148148148148 1.89262051633539 0.0232856284681691 0.160781720375453 GO:0019902 phosphatase binding 23/1459 190/18639 0.121052631578947 1.54647018505826 0.0242845563221396 0.166686895465574 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/1459 22/18639 0.227272727272727 2.90345192846906 0.0250088748418732 0.16743367945619 GO:0031683 G-protein beta/gamma-subunit complex binding 5/1459 22/18639 0.227272727272727 2.90345192846906 0.0250088748418732 0.16743367945619 GO:0140517 protein-RNA adaptor activity 5/1459 22/18639 0.227272727272727 2.90345192846906 0.0250088748418732 0.16743367945619 GO:0031386 protein tag activity 4/1459 15/18639 0.266666666666667 3.4067169294037 0.0253759739840965 0.16743367945619 GO:0042809 nuclear vitamin D receptor binding 4/1459 15/18639 0.266666666666667 3.4067169294037 0.0253759739840965 0.16743367945619 GO:0141047 molecular tag activity 4/1459 15/18639 0.266666666666667 3.4067169294037 0.0253759739840965 0.16743367945619 GO:0140272 exogenous protein binding 12/1459 82/18639 0.146341463414634 1.8695397783313 0.0254037306761116 0.16743367945619 GO:0043531 ADP binding 7/1459 38/18639 0.184210526315789 2.35332419465387 0.0262198726374588 0.171836453443233 GO:0008187 poly-pyrimidine tract binding 6/1459 30/18639 0.2 2.55503769705278 0.0265446717127959 0.171916124092242 GO:0035925 mRNA 3'-UTR AU-rich region binding 6/1459 30/18639 0.2 2.55503769705278 0.0265446717127959 0.171916124092242 GO:0043178 alcohol binding 13/1459 92/18639 0.141304347826087 1.80518967726555 0.0266766399453479 0.171916124092242 GO:0001540 amyloid-beta binding 12/1459 83/18639 0.144578313253012 1.84701520268875 0.0276592401644165 0.17726363862278 GO:0005200 structural constituent of cytoskeleton 15/1459 112/18639 0.133928571428571 1.71096274356213 0.0281804006388865 0.17862986197327 GO:0043022 ribosome binding 15/1459 112/18639 0.133928571428571 1.71096274356213 0.0281804006388865 0.17862986197327 GO:0019212 phosphatase inhibitor activity 9/1459 56/18639 0.160714285714286 2.05315529227455 0.0288607798483401 0.181948394696057 GO:0001217 DNA-binding transcription repressor activity 31/1459 278/18639 0.111510791366906 1.42457137785317 0.0291880832283861 0.183017170513124 GO:0003714 transcription corepressor activity 24/1459 204/18639 0.117647058823529 1.50296335120752 0.0294111964398692 0.183424665969077 GO:0005158 insulin receptor binding 5/1459 23/18639 0.217391304347826 2.77721488810084 0.0299546718266724 0.185815076571872 GO:0008237 metallopeptidase activity 22/1459 184/18639 0.119565217391304 1.52746818845546 0.0306551174295528 0.189066676370853 GO:0017147 Wnt-protein binding 6/1459 31/18639 0.193548387096774 2.47261712618011 0.0308048291673199 0.189066676370853 GO:0003725 double-stranded RNA binding 11/1459 75/18639 0.146666666666667 1.87369431117204 0.0310548148523907 0.189597816993543 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 8/1459 48/18639 0.166666666666667 2.12919808087731 0.0314806861641674 0.190080882413096 GO:0008235 metalloexopeptidase activity 10/1459 66/18639 0.151515151515152 1.93563461897938 0.0317521444322715 0.190080882413096 GO:0005024 transforming growth factor beta receptor activity 4/1459 16/18639 0.25 3.19379712131597 0.0317893889552936 0.190080882413096 GO:0005159 insulin-like growth factor receptor binding 4/1459 16/18639 0.25 3.19379712131597 0.0317893889552936 0.190080882413096 GO:0004601 peroxidase activity 9/1459 57/18639 0.157894736842105 2.01713502398903 0.0319790016898608 0.190234061334557 GO:0042277 peptide binding 28/1459 249/18639 0.112449799196787 1.43656737986903 0.0334756140849769 0.198120981319251 GO:0046982 protein heterodimerization activity 39/1459 369/18639 0.105691056910569 1.35022317323927 0.0340026957845504 0.2002189193405 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1459 24/18639 0.208333333333333 2.66149760109664 0.0354740740969941 0.207827908851077 GO:0008013 beta-catenin binding 14/1459 106/18639 0.132075471698113 1.68728904522353 0.0368005324824895 0.212566181446064 GO:0044325 transmembrane transporter binding 17/1459 136/18639 0.125 1.59689856065798 0.0368325883367749 0.212566181446064 GO:0140789 histone phosphatase activity 17/1459 136/18639 0.125 1.59689856065798 0.0368325883367749 0.212566181446064 GO:0001094 TFIID-class transcription factor complex binding 3/1459 10/18639 0.3 3.83255654557916 0.0378504084277103 0.215227812628157 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/1459 10/18639 0.3 3.83255654557916 0.0378504084277103 0.215227812628157 GO:0070513 death domain binding 3/1459 10/18639 0.3 3.83255654557916 0.0378504084277103 0.215227812628157 GO:0001727 lipid kinase activity 7/1459 41/18639 0.170731707317073 2.18112974138652 0.0381558311788972 0.215793778846142 GO:0001786 phosphatidylserine binding 9/1459 59/18639 0.152542372881356 1.94875756554873 0.0388998939376187 0.215793778846142 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 9/1459 59/18639 0.152542372881356 1.94875756554873 0.0388998939376187 0.215793778846142 GO:0008429 phosphatidylethanolamine binding 4/1459 17/18639 0.235294117647059 3.00592670241503 0.0390661151359395 0.215793778846142 GO:0016805 dipeptidase activity 4/1459 17/18639 0.235294117647059 3.00592670241503 0.0390661151359395 0.215793778846142 GO:0038191 neuropilin binding 4/1459 17/18639 0.235294117647059 3.00592670241503 0.0390661151359395 0.215793778846142 GO:0019199 transmembrane receptor protein kinase activity 11/1459 78/18639 0.141025641025641 1.80162914535773 0.0399322615621755 0.219532812379733 GO:0001664 G protein-coupled receptor binding 32/1459 297/18639 0.107744107744108 1.37645128460756 0.040809302378871 0.223296182827785 GO:0008139 nuclear localization sequence binding 5/1459 25/18639 0.2 2.55503769705278 0.0415800184877108 0.22538701610161 GO:0019211 phosphatase activator activity 5/1459 25/18639 0.2 2.55503769705278 0.0415800184877108 0.22538701610161 GO:0001098 basal transcription machinery binding 9/1459 60/18639 0.15 1.91627827278958 0.0427146476531115 0.227809722184427 GO:0001099 basal RNA polymerase II transcription machinery binding 9/1459 60/18639 0.15 1.91627827278958 0.0427146476531115 0.227809722184427 GO:0098531 ligand-modulated transcription factor activity 9/1459 60/18639 0.15 1.91627827278958 0.0427146476531115 0.227809722184427 GO:0051879 Hsp90 protein binding 7/1459 42/18639 0.166666666666667 2.12919808087731 0.0428125167553492 0.227809722184427 GO:0070851 growth factor receptor binding 17/1459 139/18639 0.122302158273381 1.56243312409702 0.0439638193112923 0.23286771872648 GO:0035591 signaling adaptor activity 16/1459 129/18639 0.124031007751938 1.58451950204823 0.0445195726446023 0.234739564853358 GO:0001216 DNA-binding transcription activator activity 49/1459 491/18639 0.09979633401222 1.27491697714446 0.0469143171757368 0.243332225964536 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 4/1459 18/18639 0.222222222222222 2.83893077450308 0.0472117512185819 0.243332225964536 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 29/1459 268/18639 0.108208955223881 1.38238979877855 0.0473095904950822 0.243332225964536 GO:0005160 transforming growth factor beta receptor binding 5/1459 26/18639 0.192307692307692 2.4567670163969 0.0482811961563816 0.243332225964536 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 5/1459 26/18639 0.192307692307692 2.4567670163969 0.0482811961563816 0.243332225964536 GO:0052742 phosphatidylinositol kinase activity 5/1459 26/18639 0.192307692307692 2.4567670163969 0.0482811961563816 0.243332225964536 GO:0001851 complement component C3b binding 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0008432 JUN kinase binding 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0008526 phosphatidylinositol transfer activity 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0034713 type I transforming growth factor beta receptor binding 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0047676 arachidonate-CoA ligase activity 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0048185 activin binding 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0050786 RAGE receptor binding 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0070990 snRNP binding 3/1459 11/18639 0.272727272727273 3.48414231416288 0.0490859835135357 0.243332225964536 GO:0061135 endopeptidase regulator activity 21/1459 184/18639 0.114130434782609 1.45803781625294 0.0520245992747585 0.256802277271148 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 48/1459 484/18639 0.0991735537190083 1.26696084151377 0.0532480498146099 0.261727702478591 GO:1901981 phosphatidylinositol phosphate binding 21/1459 185/18639 0.113513513513514 1.45015653075968 0.0545477220730474 0.265115350409155 GO:0005044 scavenger receptor activity 5/1459 27/18639 0.185185185185185 2.36577564541924 0.0555821129106413 0.265115350409155 GO:0005104 fibroblast growth factor receptor binding 5/1459 27/18639 0.185185185185185 2.36577564541924 0.0555821129106413 0.265115350409155 GO:0008266 poly(U) RNA binding 5/1459 27/18639 0.185185185185185 2.36577564541924 0.0555821129106413 0.265115350409155 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/1459 27/18639 0.185185185185185 2.36577564541924 0.0555821129106413 0.265115350409155 GO:0004721 phosphoprotein phosphatase activity 20/1459 175/18639 0.114285714285714 1.46002154117301 0.0562153992045819 0.265115350409155 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/1459 19/18639 0.210526315789474 2.68951336531871 0.0562227381040105 0.265115350409155 GO:0043395 heparan sulfate proteoglycan binding 4/1459 19/18639 0.210526315789474 2.68951336531871 0.0562227381040105 0.265115350409155 GO:0046624 sphingolipid transporter activity 4/1459 19/18639 0.210526315789474 2.68951336531871 0.0562227381040105 0.265115350409155 GO:0140036 ubiquitin-modified protein reader activity 4/1459 19/18639 0.210526315789474 2.68951336531871 0.0562227381040105 0.265115350409155 GO:0140463 chromatin-protein adaptor activity 8/1459 54/18639 0.148148148148148 1.89262051633539 0.0576903203036304 0.270934297782232 GO:0000287 magnesium ion binding 25/1459 230/18639 0.108695652173913 1.38860744405042 0.0593075750335068 0.276292317425172 GO:0005085 guanyl-nucleotide exchange factor activity 25/1459 230/18639 0.108695652173913 1.38860744405042 0.0593075750335068 0.276292317425172 GO:0004859 phospholipase inhibitor activity 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0004875 complement receptor activity 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0005078 MAP-kinase scaffold activity 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0005165 neurotrophin receptor binding 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0034452 dynactin binding 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0097371 MDM2/MDM4 family protein binding 3/1459 12/18639 0.25 3.19379712131597 0.0617450048739231 0.278693407213038 GO:0045499 chemorepellent activity 5/1459 28/18639 0.178571428571429 2.28128365808284 0.0634832017385105 0.28542834890183 GO:0017124 SH3 domain binding 14/1459 115/18639 0.121739130434783 1.55524033733647 0.0652010993375039 0.29038282291105 GO:0023023 MHC protein complex binding 6/1459 37/18639 0.162162162162162 2.07165218679955 0.0655541124508202 0.29038282291105 GO:0001614 purinergic nucleotide receptor activity 4/1459 20/18639 0.2 2.55503769705278 0.066087125214239 0.29038282291105 GO:0016502 nucleotide receptor activity 4/1459 20/18639 0.2 2.55503769705278 0.066087125214239 0.29038282291105 GO:0030742 GTP-dependent protein binding 4/1459 20/18639 0.2 2.55503769705278 0.066087125214239 0.29038282291105 GO:0042288 MHC class I protein binding 4/1459 20/18639 0.2 2.55503769705278 0.066087125214239 0.29038282291105 GO:0004867 serine-type endopeptidase inhibitor activity 12/1459 95/18639 0.126315789473684 1.61370801919123 0.0668764558790758 0.292742221961238 GO:0043495 protein-membrane adaptor activity 7/1459 47/18639 0.148936170212766 1.90268764674143 0.0714699122235842 0.309251616230746 GO:0098631 cell adhesion mediator activity 10/1459 76/18639 0.131578947368421 1.68094585332419 0.0717311209535379 0.309251616230746 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 11/1459 86/18639 0.127906976744186 1.63403573648724 0.0717830687379157 0.309251616230746 GO:0004629 phospholipase C activity 5/1459 29/18639 0.172413793103448 2.20261870435584 0.0719809796399151 0.309251616230746 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/1459 29/18639 0.172413793103448 2.20261870435584 0.0719809796399151 0.309251616230746 GO:1990782 protein tyrosine kinase binding 14/1459 117/18639 0.11965811965812 1.52865503242474 0.0730792091588429 0.312811374997261 GO:0015932 nucleobase-containing compound transmembrane transporter activity 8/1459 57/18639 0.140350877192982 1.79300891021247 0.0748068679829059 0.3136304654541 GO:0033218 amide binding 26/1459 247/18639 0.105263157894737 1.34475668265936 0.0750892363650286 0.3136304654541 GO:0005035 death receptor activity 3/1459 13/18639 0.230769230769231 2.94812041967628 0.0757484228658198 0.3136304654541 GO:0008035 high-density lipoprotein particle binding 3/1459 13/18639 0.230769230769231 2.94812041967628 0.0757484228658198 0.3136304654541 GO:0035325 Toll-like receptor binding 3/1459 13/18639 0.230769230769231 2.94812041967628 0.0757484228658198 0.3136304654541 GO:0043560 insulin receptor substrate binding 3/1459 13/18639 0.230769230769231 2.94812041967628 0.0757484228658198 0.3136304654541 GO:0070123 transforming growth factor beta receptor activity, type III 3/1459 13/18639 0.230769230769231 2.94812041967628 0.0757484228658198 0.3136304654541 GO:0140333 glycerophospholipid flippase activity 3/1459 13/18639 0.230769230769231 2.94812041967628 0.0757484228658198 0.3136304654541 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 4/1459 21/18639 0.19047619047619 2.43336923528836 0.0767853898180726 0.3136304654541 GO:0005123 death receptor binding 4/1459 21/18639 0.19047619047619 2.43336923528836 0.0767853898180726 0.3136304654541 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/1459 21/18639 0.19047619047619 2.43336923528836 0.0767853898180726 0.3136304654541 GO:0035613 RNA stem-loop binding 4/1459 21/18639 0.19047619047619 2.43336923528836 0.0767853898180726 0.3136304654541 GO:0072542 protein phosphatase activator activity 4/1459 21/18639 0.19047619047619 2.43336923528836 0.0767853898180726 0.3136304654541 GO:0032266 phosphatidylinositol-3-phosphate binding 7/1459 48/18639 0.145833333333333 1.86304832076765 0.0782973410629969 0.318683914502022 GO:0030145 manganese ion binding 9/1459 68/18639 0.132352941176471 1.69083377010845 0.0823050211289712 0.333824561222401 GO:0008083 growth factor activity 18/1459 162/18639 0.111111111111111 1.41946538725154 0.0832456203912549 0.336463134682424 GO:0001222 transcription corepressor binding 7/1459 49/18639 0.142857142857143 1.82502692646627 0.0854907020827647 0.34433755005558 GO:0032182 ubiquitin-like protein binding 14/1459 120/18639 0.116666666666667 1.49043865661412 0.0860189643449192 0.345266431280645 GO:0004879 nuclear receptor activity 8/1459 59/18639 0.135593220338983 1.73222894715442 0.0877476706666718 0.347701588517628 GO:0070888 E-box binding 8/1459 59/18639 0.135593220338983 1.73222894715442 0.0877476706666718 0.347701588517628 GO:0050321 tau-protein kinase activity 4/1459 22/18639 0.181818181818182 2.32276154277525 0.0882912820350058 0.347701588517628 GO:0061133 endopeptidase activator activity 4/1459 22/18639 0.181818181818182 2.32276154277525 0.0882912820350058 0.347701588517628 GO:0140035 ubiquitin-like protein reader activity 4/1459 22/18639 0.181818181818182 2.32276154277525 0.0882912820350058 0.347701588517628 GO:0002039 p53 binding 9/1459 69/18639 0.130434782608696 1.66632893286051 0.0884241108730175 0.347701588517628 GO:0030331 nuclear estrogen receptor binding 6/1459 40/18639 0.15 1.91627827278958 0.0890375450808313 0.347756068329173 GO:0071949 FAD binding 6/1459 40/18639 0.15 1.91627827278958 0.0890375450808313 0.347756068329173 GO:0070325 lipoprotein particle receptor binding 5/1459 31/18639 0.161290322580645 2.06051427181675 0.0907342820057272 0.353193849418267 GO:0005126 cytokine receptor binding 28/1459 275/18639 0.101818181818182 1.30074646395414 0.0917486550541772 0.35594795940751 GO:0015605 organophosphate ester transmembrane transporter activity 7/1459 50/18639 0.14 1.78852638793694 0.0930475421401631 0.359631703314441 GO:1902936 phosphatidylinositol bisphosphate binding 13/1459 111/18639 0.117117117117117 1.4961932460219 0.0933182264634886 0.359631703314441 GO:0042169 SH2 domain binding 6/1459 41/18639 0.146341463414634 1.8695397783313 0.0977601246068771 0.375502465377409 GO:0030971 receptor tyrosine kinase binding 10/1459 81/18639 0.123456790123457 1.57718376361282 0.100094004241622 0.376590250762604 GO:0000295 adenine nucleotide transmembrane transporter activity 4/1459 23/18639 0.173913043478261 2.22177191048067 0.100572673657813 0.376590250762604 GO:0004022 alcohol dehydrogenase (NAD+) activity 4/1459 23/18639 0.173913043478261 2.22177191048067 0.100572673657813 0.376590250762604 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 4/1459 23/18639 0.173913043478261 2.22177191048067 0.100572673657813 0.376590250762604 GO:0005021 vascular endothelial growth factor receptor activity 7/1459 51/18639 0.137254901960784 1.75345724307543 0.100964098856478 0.376590250762604 GO:0005048 signal sequence binding 7/1459 51/18639 0.137254901960784 1.75345724307543 0.100964098856478 0.376590250762604 GO:0031369 translation initiation factor binding 5/1459 32/18639 0.15625 1.99612320082248 0.100965144816526 0.376590250762604 GO:0071813 lipoprotein particle binding 5/1459 32/18639 0.15625 1.99612320082248 0.100965144816526 0.376590250762604 GO:0071814 protein-lipid complex binding 5/1459 32/18639 0.15625 1.99612320082248 0.100965144816526 0.376590250762604 GO:0008238 exopeptidase activity 12/1459 102/18639 0.117647058823529 1.50296335120752 0.101328921097379 0.376735732285127 GO:0004467 long-chain fatty acid-CoA ligase activity 3/1459 15/18639 0.2 2.55503769705278 0.107411303945343 0.393050828317345 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/1459 15/18639 0.2 2.55503769705278 0.107411303945343 0.393050828317345 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/1459 15/18639 0.2 2.55503769705278 0.107411303945343 0.393050828317345 GO:0050700 CARD domain binding 3/1459 15/18639 0.2 2.55503769705278 0.107411303945343 0.393050828317345 GO:0140776 protein-containing complex destabilizing activity 3/1459 15/18639 0.2 2.55503769705278 0.107411303945343 0.393050828317345 GO:0030159 signaling receptor complex adaptor activity 7/1459 52/18639 0.134615384615385 1.71973691147783 0.1092353418453 0.398468542580339 GO:0019956 chemokine binding 5/1459 33/18639 0.151515151515152 1.93563461897938 0.11174388337382 0.405071577230098 GO:0030296 protein tyrosine kinase activator activity 5/1459 33/18639 0.151515151515152 1.93563461897938 0.11174388337382 0.405071577230098 GO:0030414 peptidase inhibitor activity 18/1459 169/18639 0.106508875739645 1.36067096292751 0.112458651554562 0.405437466280532 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 4/1459 24/18639 0.166666666666667 2.12919808087731 0.113592393569977 0.405437466280532 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 4/1459 24/18639 0.166666666666667 2.12919808087731 0.113592393569977 0.405437466280532 GO:0005540 hyaluronic acid binding 4/1459 24/18639 0.166666666666667 2.12919808087731 0.113592393569977 0.405437466280532 GO:0035035 histone acetyltransferase binding 4/1459 24/18639 0.166666666666667 2.12919808087731 0.113592393569977 0.405437466280532 GO:0005544 calcium-dependent phospholipid binding 7/1459 53/18639 0.132075471698113 1.68728904522353 0.117855021013184 0.415537460107276 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/1459 53/18639 0.132075471698113 1.68728904522353 0.117855021013184 0.415537460107276 GO:0016860 intramolecular oxidoreductase activity 7/1459 53/18639 0.132075471698113 1.68728904522353 0.117855021013184 0.415537460107276 GO:0051018 protein kinase A binding 7/1459 53/18639 0.132075471698113 1.68728904522353 0.117855021013184 0.415537460107276 GO:0004860 protein kinase inhibitor activity 10/1459 84/18639 0.119047619047619 1.52085577205522 0.119847504515172 0.421282137083634 GO:0015035 protein-disulfide reductase activity 5/1459 34/18639 0.147058823529412 1.87870418900939 0.123050837532555 0.428053571807639 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/1459 16/18639 0.1875 2.39534784098698 0.124862515096893 0.428053571807639 GO:0004708 MAP kinase kinase activity 3/1459 16/18639 0.1875 2.39534784098698 0.124862515096893 0.428053571807639 GO:0005521 lamin binding 3/1459 16/18639 0.1875 2.39534784098698 0.124862515096893 0.428053571807639 GO:0008142 oxysterol binding 3/1459 16/18639 0.1875 2.39534784098698 0.124862515096893 0.428053571807639 GO:0055102 lipase inhibitor activity 3/1459 16/18639 0.1875 2.39534784098698 0.124862515096893 0.428053571807639 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/1459 16/18639 0.1875 2.39534784098698 0.124862515096893 0.428053571807639 GO:0140327 flippase activity 3/1459 16/18639 0.1875 2.39534784098698 0.124862515096893 0.428053571807639 GO:0001046 core promoter sequence-specific DNA binding 6/1459 44/18639 0.136363636363636 1.74207115708144 0.126498270539833 0.428053571807639 GO:0015485 cholesterol binding 7/1459 54/18639 0.12962962962963 1.65604295179347 0.126815721118863 0.428053571807639 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1459 54/18639 0.12962962962963 1.65604295179347 0.126815721118863 0.428053571807639 GO:0051287 NAD binding 7/1459 54/18639 0.12962962962963 1.65604295179347 0.126815721118863 0.428053571807639 GO:0004866 endopeptidase inhibitor activity 17/1459 161/18639 0.105590062111801 1.34893294564898 0.127218138419855 0.428053571807639 GO:0017025 TBP-class protein binding 4/1459 25/18639 0.16 2.04403015764222 0.127309036442789 0.428053571807639 GO:0042974 nuclear retinoic acid receptor binding 4/1459 25/18639 0.16 2.04403015764222 0.127309036442789 0.428053571807639 GO:0120013 lipid transfer activity 8/1459 65/18639 0.123076923076923 1.57233089049402 0.133778502311448 0.448505961506588 GO:0098632 cell-cell adhesion mediator activity 7/1459 55/18639 0.127272727272727 1.62593307994268 0.13610892177931 0.455003888368874 GO:0016887 ATP hydrolysis activity 39/1459 417/18639 0.0935251798561151 1.19480180078007 0.140658240672996 0.456502887958726 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0004435 phosphatidylinositol phospholipase C activity 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0005112 Notch binding 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0015216 purine nucleotide transmembrane transporter activity 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0050681 nuclear androgen receptor binding 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0050750 low-density lipoprotein particle receptor binding 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0070006 metalloaminopeptidase activity 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0070412 R-SMAD binding 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0120014 phospholipid transfer activity 4/1459 26/18639 0.153846153846154 1.96541361311752 0.141677734676681 0.456502887958726 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1459 17/18639 0.176470588235294 2.25444502681127 0.143247457945669 0.456502887958726 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/1459 17/18639 0.176470588235294 2.25444502681127 0.143247457945669 0.456502887958726 GO:0016018 cyclosporin A binding 3/1459 17/18639 0.176470588235294 2.25444502681127 0.143247457945669 0.456502887958726 GO:0030169 low-density lipoprotein particle binding 3/1459 17/18639 0.176470588235294 2.25444502681127 0.143247457945669 0.456502887958726 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/1459 17/18639 0.176470588235294 2.25444502681127 0.143247457945669 0.456502887958726 GO:0031489 myosin V binding 3/1459 17/18639 0.176470588235294 2.25444502681127 0.143247457945669 0.456502887958726 GO:0032183 SUMO binding 3/1459 17/18639 0.176470588235294 2.25444502681127 0.143247457945669 0.456502887958726 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/1459 46/18639 0.130434782608696 1.66632893286051 0.147678458536814 0.46933427918549 GO:0004386 helicase activity 16/1459 155/18639 0.103225806451613 1.31872913396272 0.155585615203737 0.4931128787878 GO:0004364 glutathione transferase activity 4/1459 27/18639 0.148148148148148 1.89262051633539 0.156650886288167 0.493790837212699 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/1459 27/18639 0.148148148148148 1.89262051633539 0.156650886288167 0.493790837212699 GO:0042578 phosphoric ester hydrolase activity 34/1459 363/18639 0.09366391184573 1.19657412809634 0.157587416101062 0.495279240122668 GO:0043130 ubiquitin binding 11/1459 100/18639 0.11 1.40527073337903 0.158262796609672 0.495279240122668 GO:0061749 forked DNA-dependent helicase activity 6/1459 47/18639 0.127659574468085 1.63087512577837 0.158830928728994 0.495279240122668 GO:1990518 single-stranded 3'-5' DNA helicase activity 6/1459 47/18639 0.127659574468085 1.63087512577837 0.158830928728994 0.495279240122668 GO:0032934 sterol binding 8/1459 68/18639 0.117647058823529 1.50296335120752 0.160621778976444 0.499520813974999 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1459 18/18639 0.166666666666667 2.12919808087731 0.162454599291086 0.500124739919266 GO:0031690 adrenergic receptor binding 3/1459 18/18639 0.166666666666667 2.12919808087731 0.162454599291086 0.500124739919266 GO:0019210 kinase inhibitor activity 10/1459 90/18639 0.111111111111111 1.41946538725154 0.165233170085668 0.500124739919266 GO:0009378 four-way junction helicase activity 6/1459 48/18639 0.125 1.59689856065798 0.170335726966993 0.500124739919266 GO:0036121 double-stranded DNA helicase activity 6/1459 48/18639 0.125 1.59689856065798 0.170335726966993 0.500124739919266 GO:0043138 3'-5' DNA helicase activity 6/1459 48/18639 0.125 1.59689856065798 0.170335726966993 0.500124739919266 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/1459 28/18639 0.142857142857143 1.82502692646627 0.17217883371311 0.500124739919266 GO:0072341 modified amino acid binding 10/1459 91/18639 0.10989010989011 1.40386686651251 0.173513440354881 0.500124739919266 GO:0140658 ATP-dependent chromatin remodeler activity 16/1459 158/18639 0.10126582278481 1.29368997319128 0.173889143232305 0.500124739919266 GO:0036002 pre-mRNA binding 7/1459 59/18639 0.11864406779661 1.51570032876012 0.176401365050222 0.500124739919266 GO:0033192 calmodulin-dependent protein phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:0140791 histone H2AXS140 phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:1990439 MAP kinase serine/threonine phosphatase activity 9/1459 81/18639 0.111111111111111 1.41946538725154 0.181479986537519 0.500124739919266 GO:0005031 tumor necrosis factor receptor activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0005131 growth hormone receptor binding 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0015279 store-operated calcium channel activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0031434 mitogen-activated protein kinase kinase binding 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0032395 MHC class II receptor activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0035256 G protein-coupled glutamate receptor binding 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0140135 mechanosensitive monoatomic cation channel activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0140940 histone H2A methyltransferase activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:1905394 retromer complex binding 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:1990259 histone H2AQ104 methyltransferase activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:1990757 ubiquitin ligase activator activity 2/1459 10/18639 0.2 2.55503769705278 0.181506913763221 0.500124739919266 GO:0004722 protein serine/threonine phosphatase activity 11/1459 103/18639 0.106796116504854 1.36434051784372 0.181670512613363 0.500124739919266 GO:0005004 GPI-linked ephrin receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0005008 hepatocyte growth factor receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0005009 insulin receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0005011 macrophage colony-stimulating factor receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0005020 stem cell factor receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0008288 boss receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0016763 pentosyltransferase activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0036332 placental growth factor receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0038062 protein tyrosine kinase collagen receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0060175 brain-derived neurotrophic factor receptor activity 6/1459 49/18639 0.122448979591837 1.56430879411394 0.182174567648513 0.500124739919266 GO:0022840 leak channel activity 3/1459 19/18639 0.157894736842105 2.01713502398903 0.182373073263663 0.500124739919266 GO:0022842 narrow pore channel activity 3/1459 19/18639 0.157894736842105 2.01713502398903 0.182373073263663 0.500124739919266 GO:0050145 nucleoside monophosphate kinase activity 3/1459 19/18639 0.157894736842105 2.01713502398903 0.182373073263663 0.500124739919266 GO:0016776 phosphotransferase activity, phosphate group as acceptor 5/1459 39/18639 0.128205128205128 1.63784467759793 0.186666396201403 0.510691083947234 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1459 60/18639 0.116666666666667 1.49043865661412 0.187195303898863 0.510933064759249 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 9/1459 82/18639 0.109756097560976 1.40215483374847 0.190729892767128 0.518142097447 GO:0033549 MAP kinase phosphatase activity 9/1459 82/18639 0.109756097560976 1.40215483374847 0.190729892767128 0.518142097447 GO:0005006 epidermal growth factor receptor activity 6/1459 50/18639 0.12 1.53302261823167 0.194328252945107 0.519497225257677 GO:0005007 fibroblast growth factor receptor activity 6/1459 50/18639 0.12 1.53302261823167 0.194328252945107 0.519497225257677 GO:0005017 platelet-derived growth factor receptor activity 6/1459 50/18639 0.12 1.53302261823167 0.194328252945107 0.519497225257677 GO:0005019 platelet-derived growth factor beta-receptor activity 6/1459 50/18639 0.12 1.53302261823167 0.194328252945107 0.519497225257677 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/1459 61/18639 0.114754098360656 1.46600523601389 0.198251262577458 0.519497225257677 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 9/1459 83/18639 0.108433734939759 1.38526140201657 0.200178886270952 0.519497225257677 GO:0030165 PDZ domain binding 9/1459 83/18639 0.108433734939759 1.38526140201657 0.200178886270952 0.519497225257677 GO:0015036 disulfide oxidoreductase activity 5/1459 40/18639 0.125 1.59689856065798 0.200613374932913 0.519497225257677 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/1459 40/18639 0.125 1.59689856065798 0.200613374932913 0.519497225257677 GO:0050997 quaternary ammonium group binding 5/1459 40/18639 0.125 1.59689856065798 0.200613374932913 0.519497225257677 GO:0016004 phospholipase activator activity 3/1459 20/18639 0.15 1.91627827278958 0.202894122919444 0.519497225257677 GO:0052745 inositol phosphate phosphatase activity 3/1459 20/18639 0.15 1.91627827278958 0.202894122919444 0.519497225257677 GO:0061608 nuclear import signal receptor activity 3/1459 20/18639 0.15 1.91627827278958 0.202894122919444 0.519497225257677 GO:0016769 transferase activity, transferring nitrogenous groups 4/1459 30/18639 0.133333333333333 1.70335846470185 0.204693913309356 0.519497225257677 GO:0031210 phosphatidylcholine binding 4/1459 30/18639 0.133333333333333 1.70335846470185 0.204693913309356 0.519497225257677 GO:0033612 receptor serine/threonine kinase binding 4/1459 30/18639 0.133333333333333 1.70335846470185 0.204693913309356 0.519497225257677 GO:0051721 protein phosphatase 2A binding 4/1459 30/18639 0.133333333333333 1.70335846470185 0.204693913309356 0.519497225257677 GO:0070566 adenylyltransferase activity 4/1459 30/18639 0.133333333333333 1.70335846470185 0.204693913309356 0.519497225257677 GO:0005010 insulin-like growth factor receptor activity 6/1459 51/18639 0.117647058823529 1.50296335120752 0.20677680682359 0.519497225257677 GO:0005030 neurotrophin receptor activity 6/1459 51/18639 0.117647058823529 1.50296335120752 0.20677680682359 0.519497225257677 GO:0017018 myosin phosphatase activity 9/1459 84/18639 0.107142857142857 1.3687701948497 0.209818652081646 0.519497225257677 GO:0051117 ATPase binding 9/1459 84/18639 0.107142857142857 1.3687701948497 0.209818652081646 0.519497225257677 GO:0003953 NAD+ nucleosidase activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0005114 type II transforming growth factor beta receptor binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0005536 D-glucose binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0010854 adenylate cyclase regulator activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0015173 aromatic amino acid transmembrane transporter activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0015217 ADP transmembrane transporter activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0032050 clathrin heavy chain binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0032794 GTPase activating protein binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0034056 estrogen response element binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0035252 UDP-xylosyltransferase activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0042285 xylosyltransferase activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0043522 leucine zipper domain binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0050998 nitric-oxide synthase binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0070697 activin receptor binding 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0140537 transcription regulator activator activity 2/1459 11/18639 0.181818181818182 2.32276154277525 0.21093378715204 0.519497225257677 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/1459 41/18639 0.121951219512195 1.55794981527608 0.214898548589307 0.527023924658765 GO:0042287 MHC protein binding 5/1459 41/18639 0.121951219512195 1.55794981527608 0.214898548589307 0.527023924658765 GO:0140597 protein carrier chaperone 18/1459 188/18639 0.0957446808510638 1.22315634433378 0.21882750878206 0.535527236681835 GO:0016878 acid-thiol ligase activity 4/1459 31/18639 0.129032258064516 1.6484114174534 0.221576821650635 0.539977128392303 GO:0070273 phosphatidylinositol-4-phosphate binding 4/1459 31/18639 0.129032258064516 1.6484114174534 0.221576821650635 0.539977128392303 GO:0008373 sialyltransferase activity 3/1459 21/18639 0.142857142857143 1.82502692646627 0.223912245103006 0.541237968585661 GO:0010314 phosphatidylinositol-5-phosphate binding 3/1459 21/18639 0.142857142857143 1.82502692646627 0.223912245103006 0.541237968585661 GO:0036122 BMP binding 3/1459 21/18639 0.142857142857143 1.82502692646627 0.223912245103006 0.541237968585661 GO:0005496 steroid binding 11/1459 108/18639 0.101851851851852 1.30117660498058 0.223960538725101 0.541237968585661 GO:0019894 kinesin binding 5/1459 42/18639 0.119047619047619 1.52085577205522 0.229490506608294 0.551157324359465 GO:0042056 chemoattractant activity 5/1459 42/18639 0.119047619047619 1.52085577205522 0.229490506608294 0.551157324359465 GO:0043175 RNA polymerase core enzyme binding 5/1459 42/18639 0.119047619047619 1.52085577205522 0.229490506608294 0.551157324359465 GO:0140104 molecular carrier activity 23/1459 249/18639 0.0923694779116466 1.1800374906067 0.23243446301313 0.552605723217791 GO:0005003 ephrin receptor activity 6/1459 53/18639 0.113207547169811 1.44624775304874 0.232475511146795 0.552605723217791 GO:0005005 transmembrane-ephrin receptor activity 6/1459 53/18639 0.113207547169811 1.44624775304874 0.232475511146795 0.552605723217791 GO:0005246 calcium channel regulator activity 6/1459 53/18639 0.113207547169811 1.44624775304874 0.232475511146795 0.552605723217791 GO:0038064 collagen receptor activity 6/1459 53/18639 0.113207547169811 1.44624775304874 0.232475511146795 0.552605723217791 GO:0016791 phosphatase activity 25/1459 273/18639 0.0915750915750916 1.1698890554271 0.233886544208121 0.554822886056075 GO:0022884 macromolecule transmembrane transporter activity 4/1459 32/18639 0.125 1.59689856065798 0.238807061198365 0.55525843058626 GO:0140142 nucleocytoplasmic carrier activity 4/1459 32/18639 0.125 1.59689856065798 0.238807061198365 0.55525843058626 GO:0008081 phosphoric diester hydrolase activity 9/1459 87/18639 0.103448275862069 1.3215712226135 0.23979437286605 0.55525843058626 GO:0005025 transforming growth factor beta receptor activity, type I 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0005026 transforming growth factor beta receptor activity, type II 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0015368 calcium:monoatomic cation antiporter activity 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0016361 activin receptor activity, type I 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0016362 activin receptor activity, type II 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0017002 activin receptor activity 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0035259 nuclear glucocorticoid receptor binding 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0035497 cAMP response element binding 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0036009 protein-glutamine N-methyltransferase activity 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:1990817 poly(A) RNA polymerase activity 2/1459 12/18639 0.166666666666667 2.12919808087731 0.240771543607663 0.55525843058626 GO:0004222 metalloendopeptidase activity 11/1459 110/18639 0.1 1.27751884852639 0.241894320928286 0.556740897374626 GO:0017022 myosin binding 8/1459 76/18639 0.105263157894737 1.34475668265936 0.242670494601073 0.557421334133159 GO:0004712 protein serine/threonine/tyrosine kinase activity 5/1459 43/18639 0.116279069767442 1.48548703317022 0.244357501745341 0.560187158151375 GO:0070034 telomerase RNA binding 3/1459 22/18639 0.136363636363636 1.74207115708144 0.245326081376901 0.561298332144388 GO:0001223 transcription coactivator binding 5/1459 44/18639 0.113636363636364 1.45172596423453 0.259467659592202 0.592485206942822 GO:0004602 glutathione peroxidase activity 3/1459 23/18639 0.130434782608696 1.66632893286051 0.267039092534764 0.606194417495745 GO:0043274 phospholipase binding 3/1459 23/18639 0.130434782608696 1.66632893286051 0.267039092534764 0.606194417495745 GO:0070577 lysine-acetylated histone binding 3/1459 23/18639 0.130434782608696 1.66632893286051 0.267039092534764 0.606194417495745 GO:0005172 vascular endothelial growth factor receptor binding 2/1459 13/18639 0.153846153846154 1.96541361311752 0.270775747378908 0.607543262977821 GO:0017154 semaphorin receptor activity 2/1459 13/18639 0.153846153846154 1.96541361311752 0.270775747378908 0.607543262977821 GO:0045159 myosin II binding 2/1459 13/18639 0.153846153846154 1.96541361311752 0.270775747378908 0.607543262977821 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1459 13/18639 0.153846153846154 1.96541361311752 0.270775747378908 0.607543262977821 GO:0089720 caspase binding 2/1459 13/18639 0.153846153846154 1.96541361311752 0.270775747378908 0.607543262977821 GO:0097157 pre-mRNA intronic binding 2/1459 13/18639 0.153846153846154 1.96541361311752 0.270775747378908 0.607543262977821 GO:0030332 cyclin binding 4/1459 34/18639 0.117647058823529 1.50296335120752 0.274103973990746 0.611462711210125 GO:0051427 hormone receptor binding 4/1459 34/18639 0.117647058823529 1.50296335120752 0.274103973990746 0.611462711210125 GO:0052866 phosphatidylinositol phosphate phosphatase activity 4/1459 34/18639 0.117647058823529 1.50296335120752 0.274103973990746 0.611462711210125 GO:0140303 intramembrane lipid transporter activity 5/1459 45/18639 0.111111111111111 1.41946538725154 0.274789172752638 0.611814664861921 GO:0140223 general transcription initiation factor activity 7/1459 68/18639 0.102941176470588 1.31509293230658 0.28172396877446 0.626053263943245 GO:0000049 tRNA binding 8/1459 80/18639 0.1 1.27751884852639 0.288100048189882 0.633636403505653 GO:0048306 calcium-dependent protein binding 8/1459 80/18639 0.1 1.27751884852639 0.288100048189882 0.633636403505653 GO:0005315 phosphate transmembrane transporter activity 3/1459 24/18639 0.125 1.59689856065798 0.288960049529733 0.633636403505653 GO:0030215 semaphorin receptor binding 3/1459 24/18639 0.125 1.59689856065798 0.288960049529733 0.633636403505653 GO:0060229 lipase activator activity 3/1459 24/18639 0.125 1.59689856065798 0.288960049529733 0.633636403505653 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/1459 24/18639 0.125 1.59689856065798 0.288960049529733 0.633636403505653 GO:0140033 acetylation-dependent protein binding 3/1459 24/18639 0.125 1.59689856065798 0.288960049529733 0.633636403505653 GO:0030276 clathrin binding 5/1459 46/18639 0.108695652173913 1.38860744405042 0.290290479364325 0.635352747287956 GO:0043015 gamma-tubulin binding 4/1459 35/18639 0.114285714285714 1.46002154117301 0.292070433164974 0.636845305397312 GO:0061631 ubiquitin conjugating enzyme activity 4/1459 35/18639 0.114285714285714 1.46002154117301 0.292070433164974 0.636845305397312 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/1459 128/18639 0.09375 1.19767392049349 0.300293099712187 0.640102187367322 GO:0017116 single-stranded DNA helicase activity 6/1459 58/18639 0.103448275862069 1.3215712226135 0.300390578971276 0.640102187367322 GO:0004065 arylsulfatase activity 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0008195 phosphatidate phosphatase activity 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0008331 high voltage-gated calcium channel activity 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0031404 chloride ion binding 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0034236 protein kinase A catalytic subunit binding 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0042813 Wnt receptor activity 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0044548 S100 protein binding 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0046030 inositol trisphosphate phosphatase activity 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0071933 Arp2/3 complex binding 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0098821 BMP receptor activity 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0098847 sequence-specific single stranded DNA binding 2/1459 14/18639 0.142857142857143 1.82502692646627 0.300737665616543 0.640102187367322 GO:0140674 ATP-dependent histone chaperone activity 14/1459 152/18639 0.0921052631578947 1.17666209732694 0.302374363650137 0.642407072956335 GO:0000993 RNA polymerase II complex binding 4/1459 36/18639 0.111111111111111 1.41946538725154 0.310184377567487 0.651198391002737 GO:0003774 cytoskeletal motor activity 14/1459 153/18639 0.0915032679738562 1.16897149538362 0.310928704113824 0.651198391002737 GO:0003707 nuclear steroid receptor activity 3/1459 25/18639 0.12 1.53302261823167 0.311003369496135 0.651198391002737 GO:0004709 MAP kinase kinase kinase activity 3/1459 25/18639 0.12 1.53302261823167 0.311003369496135 0.651198391002737 GO:0008483 transaminase activity 3/1459 25/18639 0.12 1.53302261823167 0.311003369496135 0.651198391002737 GO:0015645 fatty acid ligase activity 3/1459 25/18639 0.12 1.53302261823167 0.311003369496135 0.651198391002737 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/1459 25/18639 0.12 1.53302261823167 0.311003369496135 0.651198391002737 GO:0120515 fatty acid-CoA ligase activity 3/1459 25/18639 0.12 1.53302261823167 0.311003369496135 0.651198391002737 GO:0003730 mRNA 3'-UTR binding 23/1459 262/18639 0.0877862595419847 1.12148601206515 0.313464408743443 0.65516885431062 GO:0031593 polyubiquitin modification-dependent protein binding 6/1459 59/18639 0.101694915254237 1.29917171036582 0.314427093754791 0.655329821314729 GO:0042562 hormone binding 9/1459 94/18639 0.0957446808510638 1.22315634433378 0.314671302131297 0.655329821314729 GO:0005319 lipid transporter activity 16/1459 178/18639 0.0898876404494382 1.1483315492372 0.319070978015396 0.663301674727347 GO:0140693 molecular condensate scaffold activity 5/1459 48/18639 0.104166666666667 1.33074880054832 0.321708414112895 0.667588122309407 GO:0042805 actinin binding 4/1459 37/18639 0.108108108108108 1.38110145786637 0.328399499387387 0.674924316979233 GO:0004129 cytochrome-c oxidase activity 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0005041 low-density lipoprotein particle receptor activity 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0016846 carbon-sulfur lyase activity 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0030553 cGMP binding 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0031005 filamin binding 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0120283 protein serine/threonine kinase binding 2/1459 15/18639 0.133333333333333 1.70335846470185 0.330480182796728 0.674924316979233 GO:0034237 protein kinase A regulatory subunit binding 3/1459 26/18639 0.115384615384615 1.47406020983814 0.33308932186389 0.677865988354584 GO:0043548 phosphatidylinositol 3-kinase binding 3/1459 26/18639 0.115384615384615 1.47406020983814 0.33308932186389 0.677865988354584 GO:0060590 ATPase regulator activity 5/1459 49/18639 0.102040816326531 1.30359066176162 0.337564533029303 0.685389994728595 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 12/1459 132/18639 0.0909090909090909 1.16138077138763 0.337968169814445 0.685389994728595 GO:0000146 microfilament motor activity 4/1459 38/18639 0.105263157894737 1.34475668265936 0.346671386142598 0.70059025770978 GO:0005109 frizzled binding 4/1459 38/18639 0.105263157894737 1.34475668265936 0.346671386142598 0.70059025770978 GO:0003697 single-stranded DNA binding 11/1459 121/18639 0.0909090909090909 1.16138077138763 0.348116321690245 0.701564364667764 GO:0032813 tumor necrosis factor receptor superfamily binding 5/1459 50/18639 0.1 1.27751884852639 0.35347967526088 0.701564364667764 GO:0001671 ATPase activator activity 3/1459 27/18639 0.111111111111111 1.41946538725154 0.355144126310856 0.701564364667764 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/1459 27/18639 0.111111111111111 1.41946538725154 0.355144126310856 0.701564364667764 GO:0008320 protein transmembrane transporter activity 3/1459 27/18639 0.111111111111111 1.41946538725154 0.355144126310856 0.701564364667764 GO:0016405 CoA-ligase activity 3/1459 27/18639 0.111111111111111 1.41946538725154 0.355144126310856 0.701564364667764 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 11/1459 122/18639 0.0901639344262295 1.15186125686805 0.358210687404598 0.701564364667764 GO:0003678 DNA helicase activity 7/1459 74/18639 0.0945945945945946 1.20846377563307 0.358836578109605 0.701564364667764 GO:0031491 nucleosome binding 7/1459 74/18639 0.0945945945945946 1.20846377563307 0.358836578109605 0.701564364667764 GO:0050660 flavin adenine dinucleotide binding 8/1459 86/18639 0.0930232558139535 1.18838962653617 0.35953020102522 0.701564364667764 GO:0000062 fatty-acyl-CoA binding 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0005149 interleukin-1 receptor binding 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0017070 U6 snRNA binding 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0019841 retinol binding 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0022841 potassium ion leak channel activity 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0030275 LRR domain binding 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0070411 I-SMAD binding 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0097027 ubiquitin-protein transferase activator activity 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/1459 16/18639 0.125 1.59689856065798 0.359854135325276 0.701564364667764 GO:0030544 Hsp70 protein binding 5/1459 51/18639 0.0980392156862745 1.2524694593396 0.369425639221455 0.719016344793436 GO:0003689 DNA clamp loader activity 14/1459 160/18639 0.0875 1.11782899246059 0.372318472454256 0.723432877800564 GO:0016779 nucleotidyltransferase activity 12/1459 136/18639 0.0882352941176471 1.12722251340564 0.376497862611162 0.727846847338101 GO:0046625 sphingolipid binding 3/1459 28/18639 0.107142857142857 1.3687701948497 0.377099961422585 0.727846847338101 GO:0051393 alpha-actinin binding 3/1459 28/18639 0.107142857142857 1.3687701948497 0.377099961422585 0.727846847338101 GO:0141052 histone H3 demethylase activity 3/1459 28/18639 0.107142857142857 1.3687701948497 0.377099961422585 0.727846847338101 GO:0140030 modification-dependent protein binding 15/1459 173/18639 0.0867052023121387 1.10767530219051 0.378790829591226 0.72865095557136 GO:0042393 histone binding 21/1459 247/18639 0.0850202429149798 1.08614962830179 0.379058403113408 0.72865095557136 GO:0008094 ATP-dependent activity, acting on DNA 18/1459 210/18639 0.0857142857142857 1.09501615587976 0.379401014797501 0.72865095557136 GO:0004177 aminopeptidase activity 4/1459 40/18639 0.1 1.27751884852639 0.383218148015573 0.732033489846373 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 5/1459 52/18639 0.0961538461538462 1.22838350819845 0.385375217159551 0.732033489846373 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0004659 prenyltransferase activity 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0008484 sulfuric ester hydrolase activity 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0045125 bioactive lipid receptor activity 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0045236 CXCR chemokine receptor binding 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0046965 nuclear retinoid X receptor binding 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0070402 NADPH binding 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:1901567 fatty acid derivative binding 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:1990226 histone methyltransferase binding 2/1459 17/18639 0.117647058823529 1.50296335120752 0.388735025642557 0.732033489846373 GO:0003724 RNA helicase activity 7/1459 77/18639 0.0909090909090909 1.16138077138763 0.398159532824615 0.744448471273736 GO:0004181 metallocarboxypeptidase activity 3/1459 29/18639 0.103448275862069 1.3215712226135 0.398894900390789 0.744448471273736 GO:0051861 glycolipid binding 3/1459 29/18639 0.103448275862069 1.3215712226135 0.398894900390789 0.744448471273736 GO:0106222 lncRNA binding 3/1459 29/18639 0.103448275862069 1.3215712226135 0.398894900390789 0.744448471273736 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/1459 41/18639 0.0975609756097561 1.24635985222087 0.401414861467062 0.744448471273736 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/1459 41/18639 0.0975609756097561 1.24635985222087 0.401414861467062 0.744448471273736 GO:0140318 protein transporter activity 4/1459 41/18639 0.0975609756097561 1.24635985222087 0.401414861467062 0.744448471273736 GO:0000510 H3-H4 histone complex chaperone activity 13/1459 151/18639 0.0860927152317881 1.09985066429424 0.402387234041925 0.744448471273736 GO:0140584 chromatin extrusion motor activity 13/1459 151/18639 0.0860927152317881 1.09985066429424 0.402387234041925 0.744448471273736 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 13/1459 151/18639 0.0860927152317881 1.09985066429424 0.402387234041925 0.744448471273736 GO:0140849 ATP-dependent H2AZ histone chaperone activity 13/1459 151/18639 0.0860927152317881 1.09985066429424 0.402387234041925 0.744448471273736 GO:0140713 histone chaperone activity 14/1459 164/18639 0.0853658536585366 1.09056487069326 0.408156412865034 0.753919488731591 GO:0015616 DNA translocase activity 13/1459 152/18639 0.0855263157894737 1.09261480466073 0.411740955733243 0.757325312899167 GO:0004706 JUN kinase kinase kinase activity 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:0016854 racemase and epimerase activity 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:0030228 lipoprotein particle receptor activity 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:0035615 clathrin adaptor activity 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:0099602 neurotransmitter receptor regulator activity 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:1990381 ubiquitin-specific protease binding 2/1459 18/18639 0.111111111111111 1.41946538725154 0.41702007893649 0.757325312899167 GO:0017069 snRNA binding 5/1459 54/18639 0.0925925925925926 1.18288782270962 0.417181788743593 0.757325312899167 GO:0050661 NADP binding 5/1459 54/18639 0.0925925925925926 1.18288782270962 0.417181788743593 0.757325312899167 GO:0031490 chromatin DNA binding 11/1459 128/18639 0.0859375 1.09786776045236 0.419395105984512 0.759179575499333 GO:0008307 structural constituent of muscle 4/1459 42/18639 0.0952380952380952 1.21668461764418 0.419512161978511 0.759179575499333 GO:0032452 histone demethylase activity 3/1459 30/18639 0.1 1.27751884852639 0.420472787844281 0.759686513724722 GO:0061775 cohesin loader activity 13/1459 153/18639 0.0849673202614379 1.08547353142765 0.421102093383617 0.759686513724722 GO:0008186 ATP-dependent activity, acting on RNA 7/1459 79/18639 0.0886075949367089 1.13197872654237 0.424378403851466 0.76440830507407 GO:0016500 protein-hormone receptor activity 6/1459 67/18639 0.0895522388059701 1.14404673002363 0.428601005231139 0.769624096080684 GO:0042054 histone methyltransferase activity 6/1459 67/18639 0.0895522388059701 1.14404673002363 0.428601005231139 0.769624096080684 GO:0004175 endopeptidase activity 33/1459 405/18639 0.0814814814814815 1.04094128398446 0.431008995350507 0.772751830922083 GO:0008375 acetylglucosaminyltransferase activity 4/1459 43/18639 0.0930232558139535 1.18838962653617 0.437476742515245 0.782649023456979 GO:0016853 isomerase activity 15/1459 180/18639 0.0833333333333333 1.06459904043866 0.439424453084885 0.782649023456979 GO:0005452 solute:inorganic anion antiporter activity 3/1459 31/18639 0.0967741935483871 1.23630856309005 0.441783069936458 0.782649023456979 GO:0140457 protein demethylase activity 3/1459 31/18639 0.0967741935483871 1.23630856309005 0.441783069936458 0.782649023456979 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0016918 retinal binding 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0022821 solute:potassium antiporter activity 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0042577 lipid phosphatase activity 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0042834 peptidoglycan binding 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0070003 threonine-type peptidase activity 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0097001 ceramide binding 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0120227 acyl-CoA binding 2/1459 19/18639 0.105263157894737 1.34475668265936 0.444625609015646 0.782649023456979 GO:0016248 channel inhibitor activity 4/1459 44/18639 0.0909090909090909 1.16138077138763 0.45527765080755 0.798974394760602 GO:0019205 nucleobase-containing compound kinase activity 4/1459 44/18639 0.0909090909090909 1.16138077138763 0.45527765080755 0.798974394760602 GO:0005125 cytokine activity 19/1459 234/18639 0.0811965811965812 1.03730162914536 0.468699896819704 0.819973327002322 GO:0000339 RNA cap binding 2/1459 20/18639 0.1 1.27751884852639 0.471484663026335 0.819973327002322 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/1459 20/18639 0.1 1.27751884852639 0.471484663026335 0.819973327002322 GO:0010851 cyclase regulator activity 2/1459 20/18639 0.1 1.27751884852639 0.471484663026335 0.819973327002322 GO:0016505 peptidase activator activity involved in apoptotic process 2/1459 20/18639 0.1 1.27751884852639 0.471484663026335 0.819973327002322 GO:0140939 histone H4 methyltransferase activity 2/1459 20/18639 0.1 1.27751884852639 0.471484663026335 0.819973327002322 GO:0141110 transporter inhibitor activity 4/1459 45/18639 0.0888888888888889 1.13557230980123 0.472886282812907 0.821179772549359 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1459 33/18639 0.0909090909090909 1.16138077138763 0.483425345213918 0.838226308592145 GO:0015297 antiporter activity 11/1459 135/18639 0.0814814814814815 1.04094128398446 0.490642017940832 0.849469762405022 GO:0019200 carbohydrate kinase activity 2/1459 21/18639 0.0952380952380952 1.21668461764418 0.49754491754458 0.856308760165746 GO:0051010 microtubule plus-end binding 2/1459 21/18639 0.0952380952380952 1.21668461764418 0.49754491754458 0.856308760165746 GO:0051428 peptide hormone receptor binding 2/1459 21/18639 0.0952380952380952 1.21668461764418 0.49754491754458 0.856308760165746 GO:0140312 cargo adaptor activity 2/1459 21/18639 0.0952380952380952 1.21668461764418 0.49754491754458 0.856308760165746 GO:0061630 ubiquitin protein ligase activity 28/1459 353/18639 0.0793201133144476 1.01332939826456 0.499662303318186 0.858678921257919 GO:0019825 oxygen binding 3/1459 34/18639 0.0882352941176471 1.12722251340564 0.503682252106483 0.863030151319823 GO:0090482 vitamin transmembrane transporter activity 3/1459 34/18639 0.0882352941176471 1.12722251340564 0.503682252106483 0.863030151319823 GO:0008170 N-methyltransferase activity 8/1459 98/18639 0.0816326530612245 1.0428725294093 0.504461543701657 0.863090546746197 GO:0005504 fatty acid binding 4/1459 47/18639 0.0851063829787234 1.08725008385224 0.507423888026079 0.866880279985643 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/1459 60/18639 0.0833333333333333 1.06459904043866 0.510213047124996 0.870363433330875 GO:0004521 RNA endonuclease activity 6/1459 73/18639 0.0821917808219178 1.0500154919395 0.512494853016973 0.872972143171349 GO:0008093 cytoskeletal anchor activity 2/1459 22/18639 0.0909090909090909 1.16138077138763 0.522766801161348 0.884673412192008 GO:0008649 rRNA methyltransferase activity 2/1459 22/18639 0.0909090909090909 1.16138077138763 0.522766801161348 0.884673412192008 GO:0008970 phospholipase A1 activity 2/1459 22/18639 0.0909090909090909 1.16138077138763 0.522766801161348 0.884673412192008 GO:0140566 histone reader activity 3/1459 35/18639 0.0857142857142857 1.09501615587976 0.523520860132249 0.884673412192008 GO:0016836 hydro-lyase activity 5/1459 61/18639 0.0819672131147541 1.04714659715278 0.525162436167828 0.884673412192008 GO:0061659 ubiquitin-like protein ligase activity 29/1459 372/18639 0.0779569892473118 0.995915231378098 0.537651348053542 0.884673412192008 GO:0004197 cysteine-type endopeptidase activity 7/1459 88/18639 0.0795454545454545 1.01620817496417 0.539325813537102 0.884673412192008 GO:0004033 aldo-keto reductase (NADPH) activity 3/1459 36/18639 0.0833333333333333 1.06459904043866 0.542915085819955 0.884673412192008 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1459 36/18639 0.0833333333333333 1.06459904043866 0.542915085819955 0.884673412192008 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1459 36/18639 0.0833333333333333 1.06459904043866 0.542915085819955 0.884673412192008 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1459 36/18639 0.0833333333333333 1.06459904043866 0.542915085819955 0.884673412192008 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:0005212 structural constituent of eye lens 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:0016849 phosphorus-oxygen lyase activity 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:0031681 G-protein beta-subunit binding 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:0099186 structural constituent of postsynapse 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:0140102 catalytic activity, acting on a rRNA 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:0140103 catalytic activity, acting on a glycoprotein 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1459 23/18639 0.0869565217391304 1.11088595524034 0.547121821030546 0.884673412192008 GO:0000182 rDNA binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0003796 lysozyme activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0004382 GDP phosphatase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0004935 adrenergic receptor activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0005381 iron ion transmembrane transporter activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0008140 cAMP response element binding protein binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0008190 eukaryotic initiation factor 4E binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0031720 haptoglobin binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0031996 thioesterase binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0032356 oxidized DNA binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0035374 chondroitin sulfate binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0043121 neurotrophin binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0043208 glycosphingolipid binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0045322 unmethylated CpG binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0050308 sugar-phosphatase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0050815 phosphoserine residue binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0051864 histone H3K36 demethylase activity 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0051880 G-quadruplex DNA binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0070097 delta-catenin binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0071723 lipopeptide binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0097177 mitochondrial ribosome binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0098505 G-rich strand telomeric DNA binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:1990763 arrestin family protein binding 1/1459 10/18639 0.1 1.27751884852639 0.557496779579619 0.884673412192008 GO:0016247 channel regulator activity 13/1459 168/18639 0.0773809523809524 0.988556251835896 0.559017594037509 0.885731880038004 GO:0020037 heme binding 11/1459 142/18639 0.0774647887323944 0.989627277027483 0.559690920748152 0.885731880038004 GO:0140375 immune receptor activity 12/1459 156/18639 0.0769230769230769 0.98270680655876 0.568463561642592 0.898080928986149 GO:0019957 C-C chemokine binding 2/1459 24/18639 0.0833333333333333 1.06459904043866 0.570591072985166 0.898080928986149 GO:0050699 WW domain binding 2/1459 24/18639 0.0833333333333333 1.06459904043866 0.570591072985166 0.898080928986149 GO:0070300 phosphatidic acid binding 2/1459 24/18639 0.0833333333333333 1.06459904043866 0.570591072985166 0.898080928986149 GO:0141108 transporter regulator activity 13/1459 170/18639 0.0764705882352941 0.976926178284885 0.576592774206194 0.905355451907253 GO:0005501 retinoid binding 3/1459 38/18639 0.0789473684210526 1.00856751199452 0.580286207013571 0.905355451907253 GO:0019840 isoprenoid binding 3/1459 38/18639 0.0789473684210526 1.00856751199452 0.580286207013571 0.905355451907253 GO:0042162 telomeric DNA binding 3/1459 38/18639 0.0789473684210526 1.00856751199452 0.580286207013571 0.905355451907253 GO:0016835 carbon-oxygen lyase activity 6/1459 79/18639 0.0759493670886076 0.970267479893459 0.591300727693051 0.905355451907253 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0002162 dystroglycan binding 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0004016 adenylate cyclase activity 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0008503 benzodiazepine receptor activity 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0019107 myristoyltransferase activity 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0019203 carbohydrate phosphatase activity 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0019215 intermediate filament binding 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0019864 IgG binding 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0042608 T cell receptor binding 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0045294 alpha-catenin binding 1/1459 11/18639 0.0909090909090909 1.16138077138763 0.592153078822377 0.905355451907253 GO:0000030 mannosyltransferase activity 2/1459 25/18639 0.08 1.02201507882111 0.593163916766821 0.905355451907253 GO:0015271 outward rectifier potassium channel activity 2/1459 25/18639 0.08 1.02201507882111 0.593163916766821 0.905355451907253 GO:0015662 P-type ion transporter activity 2/1459 25/18639 0.08 1.02201507882111 0.593163916766821 0.905355451907253 GO:0017056 structural constituent of nuclear pore 2/1459 25/18639 0.08 1.02201507882111 0.593163916766821 0.905355451907253 GO:0120020 cholesterol transfer activity 2/1459 25/18639 0.08 1.02201507882111 0.593163916766821 0.905355451907253 GO:0140358 P-type transmembrane transporter activity 2/1459 25/18639 0.08 1.02201507882111 0.593163916766821 0.905355451907253 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/1459 39/18639 0.0769230769230769 0.98270680655876 0.598230251705759 0.906073030677277 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1459 39/18639 0.0769230769230769 0.98270680655876 0.598230251705759 0.906073030677277 GO:0017046 peptide hormone binding 4/1459 53/18639 0.0754716981132075 0.964165168699161 0.604145388631569 0.906073030677277 GO:1901505 carbohydrate derivative transmembrane transporter activity 4/1459 53/18639 0.0754716981132075 0.964165168699161 0.604145388631569 0.906073030677277 GO:0099106 ion channel regulator activity 12/1459 160/18639 0.075 0.958139136394791 0.604362652123532 0.906073030677277 GO:0004842 ubiquitin-protein transferase activity 34/1459 449/18639 0.0757238307349666 0.967386210465416 0.606706222982385 0.906073030677277 GO:0016829 lyase activity 15/1459 200/18639 0.075 0.958139136394791 0.607193924707352 0.906073030677277 GO:0030246 carbohydrate binding 21/1459 280/18639 0.075 0.958139136394791 0.614003331410604 0.906073030677277 GO:0008157 protein phosphatase 1 binding 2/1459 26/18639 0.0769230769230769 0.98270680655876 0.614836799675398 0.906073030677277 GO:0019865 immunoglobulin binding 2/1459 26/18639 0.0769230769230769 0.98270680655876 0.614836799675398 0.906073030677277 GO:0030247 polysaccharide binding 2/1459 26/18639 0.0769230769230769 0.98270680655876 0.614836799675398 0.906073030677277 GO:0016757 glycosyltransferase activity 20/1459 267/18639 0.0749063670411985 0.956942957697669 0.615087736585811 0.906073030677277 GO:0032451 demethylase activity 3/1459 40/18639 0.075 0.958139136394791 0.615663665518477 0.906073030677277 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/1459 40/18639 0.075 0.958139136394791 0.615663665518477 0.906073030677277 GO:0003720 telomerase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0005049 nuclear export signal receptor activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0005095 GTPase inhibitor activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0005436 sodium:phosphate symporter activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0008504 monoamine transmembrane transporter activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0010853 cyclase activator activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0016208 AMP binding 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0016273 arginine N-methyltransferase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0016274 protein-arginine N-methyltransferase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0017166 vinculin binding 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0035251 UDP-glucosyltransferase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0043047 single-stranded telomeric DNA binding 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0045295 gamma-catenin binding 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0070008 serine-type exopeptidase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0070410 co-SMAD binding 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0140900 chloride:bicarbonate antiporter activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/1459 12/18639 0.0833333333333333 1.06459904043866 0.624096854750987 0.906073030677277 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/1459 41/18639 0.0731707317073171 0.93476988916565 0.632578044785695 0.916093048628472 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1459 41/18639 0.0731707317073171 0.93476988916565 0.632578044785695 0.916093048628472 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1459 27/18639 0.0740740740740741 0.946310258167695 0.635612213544561 0.919339361236522 GO:0016279 protein-lysine N-methyltransferase activity 5/1459 69/18639 0.072463768115942 0.925738296033614 0.636443098292672 0.919394762166251 GO:0016755 aminoacyltransferase activity 37/1459 496/18639 0.0745967741935484 0.952987850715249 0.646039971301635 0.919728603707603 GO:0016859 cis-trans isomerase activity 3/1459 42/18639 0.0714285714285714 0.912513463233134 0.648967728078555 0.919728603707603 GO:0031492 nucleosomal DNA binding 3/1459 42/18639 0.0714285714285714 0.912513463233134 0.648967728078555 0.919728603707603 GO:0048487 beta-tubulin binding 3/1459 42/18639 0.0714285714285714 0.912513463233134 0.648967728078555 0.919728603707603 GO:0016278 lysine N-methyltransferase activity 5/1459 70/18639 0.0714285714285714 0.912513463233134 0.649168717982009 0.919728603707603 GO:0046906 tetrapyrrole binding 11/1459 152/18639 0.0723684210526316 0.924520219328307 0.651121166308163 0.919728603707603 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0003964 RNA-directed DNA polymerase activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0004465 lipoprotein lipase activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0004535 poly(A)-specific ribonuclease activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0005542 folic acid binding 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0019855 calcium channel inhibitor activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0031432 titin binding 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0039706 co-receptor binding 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0051011 microtubule minus-end binding 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0070700 BMP receptor binding 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0071837 HMG box domain binding 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:1901338 catecholamine binding 1/1459 13/18639 0.0769230769230769 0.98270680655876 0.653540280365327 0.919728603707603 GO:0019789 SUMO transferase activity 2/1459 28/18639 0.0714285714285714 0.912513463233134 0.655497771400098 0.919728603707603 GO:0051959 dynein light intermediate chain binding 2/1459 28/18639 0.0714285714285714 0.912513463233134 0.655497771400098 0.919728603707603 GO:0140767 enzyme-substrate adaptor activity 10/1459 139/18639 0.0719424460431655 0.919078308292365 0.655703064884645 0.919728603707603 GO:0005245 voltage-gated calcium channel activity 3/1459 43/18639 0.0697674418604651 0.891292219902131 0.664829551995803 0.930280193383753 GO:0008200 ion channel inhibitor activity 3/1459 43/18639 0.0697674418604651 0.891292219902131 0.664829551995803 0.930280193383753 GO:0004519 endonuclease activity 9/1459 127/18639 0.0708661417322835 0.905328317853346 0.670327706741571 0.931117422080707 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1459 29/18639 0.0689655172413793 0.881047481742336 0.674505391474862 0.931117422080707 GO:0097472 cyclin-dependent protein kinase activity 2/1459 29/18639 0.0689655172413793 0.881047481742336 0.674505391474862 0.931117422080707 GO:0043014 alpha-tubulin binding 3/1459 44/18639 0.0681818181818182 0.871035578540719 0.680162617936407 0.931117422080707 GO:0005344 oxygen carrier activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0005545 1-phosphatidylinositol binding 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0008494 translation activator activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0008559 ABC-type xenobiotic transporter activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0015386 potassium:proton antiporter activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0015926 glucosidase activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0019763 immunoglobulin receptor activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0032454 histone H3K9 demethylase activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0061665 SUMO ligase activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0061783 peptidoglycan muralytic activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0070742 C2H2 zinc finger domain binding 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:1901474 azole transmembrane transporter activity 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:1990825 sequence-specific mRNA binding 1/1459 14/18639 0.0714285714285714 0.912513463233134 0.68067894303831 0.931117422080707 GO:0015459 potassium channel regulator activity 4/1459 59/18639 0.0677966101694915 0.866114473577212 0.688376886134159 0.940538501667402 GO:0019787 ubiquitin-like protein transferase activity 35/1459 479/18639 0.0730688935281837 0.933468887232225 0.691088801479545 0.941939823962755 GO:0001965 G-protein alpha-subunit binding 2/1459 30/18639 0.0666666666666667 0.851679232350925 0.692650577448474 0.941939823962755 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/1459 30/18639 0.0666666666666667 0.851679232350925 0.692650577448474 0.941939823962755 GO:0098918 structural constituent of synapse 2/1459 30/18639 0.0666666666666667 0.851679232350925 0.692650577448474 0.941939823962755 GO:0042605 peptide antigen binding 3/1459 45/18639 0.0666666666666667 0.851679232350925 0.694968070445228 0.942880656978321 GO:0051539 4 iron, 4 sulfur cluster binding 3/1459 45/18639 0.0666666666666667 0.851679232350925 0.694968070445228 0.942880656978321 GO:0009055 electron transfer activity 8/1459 116/18639 0.0689655172413793 0.881047481742336 0.695930715190455 0.943083679463701 GO:0000774 adenyl-nucleotide exchange factor activity 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0004089 carbonate dehydratase activity 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0004953 icosanoid receptor activity 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0005523 tropomyosin binding 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0008242 omega peptidase activity 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0015929 hexosaminidase activity 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0033130 acetylcholine receptor binding 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0045504 dynein heavy chain binding 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0050780 dopamine receptor binding 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0051371 muscle alpha-actinin binding 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0061578 K63-linked deubiquitinase activity 1/1459 15/18639 0.0666666666666667 0.851679232350925 0.705693140198423 0.943092215011717 GO:0008194 UDP-glycosyltransferase activity 10/1459 145/18639 0.0689655172413793 0.881047481742336 0.706927058196029 0.943654070779509 GO:0030291 protein serine/threonine kinase inhibitor activity 3/1459 46/18639 0.0652173913043478 0.833164466430253 0.709248887499652 0.945515580299876 GO:0005164 tumor necrosis factor receptor binding 2/1459 31/18639 0.0645161290322581 0.824205708726702 0.709951784863096 0.945515580299876 GO:0008234 cysteine-type peptidase activity 13/1459 187/18639 0.0695187165775401 0.888114707531714 0.712067205316244 0.947245364870233 GO:0019905 syntaxin binding 4/1459 61/18639 0.0655737704918033 0.837717277722222 0.713449572071093 0.947700589320285 GO:0051536 iron-sulfur cluster binding 5/1459 76/18639 0.0657894736842105 0.840472926662097 0.719414037472289 0.947700589320285 GO:0015085 calcium ion transmembrane transporter activity 10/1459 147/18639 0.0680272108843537 0.869060441174414 0.722881459184393 0.947700589320285 GO:0140359 ABC-type transporter activity 3/1459 47/18639 0.0638297872340425 0.815437562889184 0.723009682918305 0.947700589320285 GO:0140938 histone H3 methyltransferase activity 3/1459 47/18639 0.0638297872340425 0.815437562889184 0.723009682918305 0.947700589320285 GO:0015106 bicarbonate transmembrane transporter activity 2/1459 32/18639 0.0625 0.798449280328992 0.726429864648517 0.947700589320285 GO:0030515 snoRNA binding 2/1459 32/18639 0.0625 0.798449280328992 0.726429864648517 0.947700589320285 GO:0120015 sterol transfer activity 2/1459 32/18639 0.0625 0.798449280328992 0.726429864648517 0.947700589320285 GO:0003688 DNA replication origin binding 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0015378 sodium:chloride symporter activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0015385 sodium:proton antiporter activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0015562 efflux transmembrane transporter activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0022858 alanine transmembrane transporter activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0043023 ribosomal large subunit binding 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1459 16/18639 0.0625 0.798449280328992 0.728749073856633 0.947700589320285 GO:0051540 metal cluster binding 5/1459 77/18639 0.0649350649350649 0.829557693848304 0.730085123199122 0.948374852083966 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/1459 48/18639 0.0625 0.798449280328992 0.736256520917707 0.954254261748089 GO:0038187 pattern recognition receptor activity 3/1459 48/18639 0.0625 0.798449280328992 0.736256520917707 0.954254261748089 GO:0008528 G protein-coupled peptide receptor activity 8/1459 122/18639 0.0655737704918033 0.837717277722222 0.747956326517142 0.955678940952666 GO:0035254 glutamate receptor binding 3/1459 49/18639 0.0612244897959184 0.782154397056972 0.748996742714775 0.955678940952666 GO:0004549 tRNA-specific ribonuclease activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0004550 nucleoside diphosphate kinase activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0005092 GDP-dissociation inhibitor activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0009881 photoreceptor activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0017110 nucleoside diphosphate phosphatase activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0030548 acetylcholine receptor regulator activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0032977 membrane insertase activity 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0036041 long-chain fatty acid binding 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0048038 quinone binding 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0051787 misfolded protein binding 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0070403 NAD+ binding 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0070492 oligosaccharide binding 1/1459 17/18639 0.0588235294117647 0.751481675603758 0.749999951870013 0.955678940952666 GO:0033293 monocarboxylic acid binding 5/1459 79/18639 0.0632911392405063 0.808556233244549 0.75053751311024 0.955678940952666 GO:0015631 tubulin binding 27/1459 385/18639 0.0701298701298701 0.895922309356168 0.75296220776298 0.956715057852796 GO:0016410 N-acyltransferase activity 6/1459 94/18639 0.0638297872340425 0.815437562889184 0.754335831854516 0.956715057852796 GO:0008175 tRNA methyltransferase activity 2/1459 34/18639 0.0588235294117647 0.751481675603758 0.757009158296863 0.956715057852796 GO:0008376 acetylgalactosaminyltransferase activity 2/1459 34/18639 0.0588235294117647 0.751481675603758 0.757009158296863 0.956715057852796 GO:0015020 glucuronosyltransferase activity 2/1459 34/18639 0.0588235294117647 0.751481675603758 0.757009158296863 0.956715057852796 GO:0016831 carboxy-lyase activity 2/1459 34/18639 0.0588235294117647 0.751481675603758 0.757009158296863 0.956715057852796 GO:0004620 phospholipase activity 7/1459 109/18639 0.0642201834862385 0.820424948594928 0.758894365817516 0.956715057852796 GO:0008276 protein methyltransferase activity 6/1459 95/18639 0.0631578947368421 0.806854009595613 0.763275568223007 0.956715057852796 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1459 167/18639 0.0658682634730539 0.841479481065285 0.766204869428447 0.956715057852796 GO:0016874 ligase activity 11/1459 167/18639 0.0658682634730539 0.841479481065285 0.766204869428447 0.956715057852796 GO:0000400 four-way junction DNA binding 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0004970 glutamate-gated receptor activity 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0015373 monoatomic anion:sodium symporter activity 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0022851 GABA-gated chloride ion channel activity 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0050811 GABA receptor binding 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0070628 proteasome binding 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:1901611 phosphatidylglycerol binding 1/1459 18/18639 0.0555555555555556 0.709732693625771 0.769587003219044 0.956715057852796 GO:0005154 epidermal growth factor receptor binding 2/1459 35/18639 0.0571428571428571 0.730010770586507 0.771159964246233 0.956715057852796 GO:0016229 steroid dehydrogenase activity 2/1459 35/18639 0.0571428571428571 0.730010770586507 0.771159964246233 0.956715057852796 GO:0034061 DNA polymerase activity 2/1459 35/18639 0.0571428571428571 0.730010770586507 0.771159964246233 0.956715057852796 GO:0004896 cytokine receptor activity 6/1459 96/18639 0.0625 0.798449280328992 0.771972576093788 0.956715057852796 GO:0016830 carbon-carbon lyase activity 3/1459 51/18639 0.0588235294117647 0.751481675603758 0.772992129773398 0.956715057852796 GO:0140097 catalytic activity, acting on DNA 23/1459 336/18639 0.068452380952381 0.874492068931754 0.778821457771417 0.956715057852796 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/1459 36/18639 0.0555555555555556 0.709732693625771 0.784586133565426 0.956715057852796 GO:0005484 SNAP receptor activity 2/1459 36/18639 0.0555555555555556 0.709732693625771 0.784586133565426 0.956715057852796 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1459 36/18639 0.0555555555555556 0.709732693625771 0.784586133565426 0.956715057852796 GO:0045505 dynein intermediate chain binding 2/1459 36/18639 0.0555555555555556 0.709732693625771 0.784586133565426 0.956715057852796 GO:0003756 protein disulfide isomerase activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0004890 GABA-A receptor activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0008301 DNA binding, bending 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0008574 plus-end-directed microtubule motor activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0015245 fatty acid transmembrane transporter activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0030506 ankyrin binding 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0034987 immunoglobulin receptor binding 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0042800 histone H3K4 methyltransferase activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0046527 glucosyltransferase activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0141147 intracellularly calcium-gated channel activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:1990380 K48-linked deubiquitinase activity 1/1459 19/18639 0.0526315789473684 0.672378341329678 0.787640414008121 0.956715057852796 GO:0042626 ATPase-coupled transmembrane transporter activity 6/1459 98/18639 0.0612244897959184 0.782154397056972 0.788645371034907 0.956901017938019 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/1459 68/18639 0.0588235294117647 0.751481675603758 0.789443339798866 0.956901017938019 GO:0001653 peptide receptor activity 8/1459 128/18639 0.0625 0.798449280328992 0.793424334437769 0.960722576145942 GO:0008146 sulfotransferase activity 3/1459 53/18639 0.0566037735849057 0.72312387652437 0.795074260473213 0.961418510576973 GO:0022829 wide pore channel activity 2/1459 37/18639 0.0540540540540541 0.690550728933183 0.797314316530214 0.961418510576973 GO:0030551 cyclic nucleotide binding 2/1459 37/18639 0.0540540540540541 0.690550728933183 0.797314316530214 0.961418510576973 GO:0070001 aspartic-type peptidase activity 2/1459 37/18639 0.0540540540540541 0.690550728933183 0.797314316530214 0.961418510576973 GO:0001972 retinoic acid binding 1/1459 20/18639 0.05 0.638759424263194 0.804280190375584 0.967177669333727 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1459 20/18639 0.05 0.638759424263194 0.804280190375584 0.967177669333727 GO:0101005 deubiquitinase activity 7/1459 115/18639 0.0608695652173913 0.777620168668236 0.805293003634468 0.967177669333727 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/1459 54/18639 0.0555555555555556 0.709732693625771 0.80542554187619 0.967177669333727 GO:0016798 hydrolase activity, acting on glycosyl bonds 8/1459 130/18639 0.0615384615384615 0.786165445247008 0.80714068554306 0.968234948531489 GO:0005262 calcium channel activity 8/1459 131/18639 0.0610687022900763 0.780164182306191 0.813734614391428 0.973970899974588 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1459 21/18639 0.0476190476190476 0.60834230882209 0.819616954017134 0.973970899974588 GO:0009975 cyclase activity 1/1459 21/18639 0.0476190476190476 0.60834230882209 0.819616954017134 0.973970899974588 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1459 21/18639 0.0476190476190476 0.60834230882209 0.819616954017134 0.973970899974588 GO:1904047 S-adenosyl-L-methionine binding 1/1459 21/18639 0.0476190476190476 0.60834230882209 0.819616954017134 0.973970899974588 GO:0005179 hormone activity 8/1459 132/18639 0.0606060606060606 0.77425384759175 0.820154643921826 0.973970899974588 GO:0004252 serine-type endopeptidase activity 11/1459 176/18639 0.0625 0.798449280328992 0.821089778314012 0.973970899974588 GO:0170055 lipid transmembrane transporter activity 3/1459 56/18639 0.0535714285714286 0.684385097424851 0.824808444795879 0.973970899974588 GO:0022853 active monoatomic ion transmembrane transporter activity 7/1459 118/18639 0.0593220338983051 0.757850164380061 0.825772765050102 0.973970899974588 GO:0071855 neuropeptide receptor binding 2/1459 40/18639 0.05 0.638759424263194 0.831580302437468 0.973970899974588 GO:0005243 gap junction channel activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0015377 chloride:monoatomic cation symporter activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0016881 acid-amino acid ligase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0032931 histone H3K56 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0043992 histone H3K9 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0043993 histone H3K18 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0043994 histone H3K23 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0043999 histone H2AK5 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0044012 histone H2AK9 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0044014 histone H2BK5 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0044015 histone H2BK12 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0044016 histone H3K4 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0044017 histone H3K27 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0044018 histone H3K36 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0046972 histone H4K16 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0140908 histone H3K122 acetyltransferase activity 1/1459 22/18639 0.0454545454545455 0.580690385693813 0.833752675581695 0.973970899974588 GO:0008236 serine-type peptidase activity 12/1459 194/18639 0.0618556701030928 0.790217844449312 0.839280341569898 0.976407919398346 GO:0048029 monosaccharide binding 4/1459 74/18639 0.0540540540540541 0.690550728933183 0.840927388535234 0.976407919398346 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/1459 41/18639 0.0487804878048781 0.623179926110433 0.841785546419611 0.976407919398346 GO:0004540 RNA nuclease activity 7/1459 121/18639 0.0578512396694215 0.739060490883034 0.844521258689313 0.976407919398346 GO:0015399 primary active transmembrane transporter activity 10/1459 166/18639 0.0602409638554217 0.769589667786981 0.845616512545359 0.976407919398346 GO:0000149 SNARE binding 6/1459 106/18639 0.0566037735849057 0.72312387652437 0.846102962388175 0.976407919398346 GO:0003887 DNA-directed DNA polymerase activity 1/1459 23/18639 0.0434782608695652 0.555442977620169 0.846781350788566 0.976407919398346 GO:0008171 O-methyltransferase activity 1/1459 23/18639 0.0434782608695652 0.555442977620169 0.846781350788566 0.976407919398346 GO:0016493 C-C chemokine receptor activity 1/1459 23/18639 0.0434782608695652 0.555442977620169 0.846781350788566 0.976407919398346 GO:0016917 GABA receptor activity 1/1459 23/18639 0.0434782608695652 0.555442977620169 0.846781350788566 0.976407919398346 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1459 23/18639 0.0434782608695652 0.555442977620169 0.846781350788566 0.976407919398346 GO:0044013 histone H2B acetyltransferase activity 1/1459 23/18639 0.0434782608695652 0.555442977620169 0.846781350788566 0.976407919398346 GO:0071617 lysophospholipid acyltransferase activity 1/1459 23/18639 0.0434782608695652 0.555442977620169 0.846781350788566 0.976407919398346 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/1459 91/18639 0.0549450549450549 0.701933433256257 0.849458105486206 0.978521750113206 GO:0016758 hexosyltransferase activity 12/1459 197/18639 0.0609137055837563 0.778184070168358 0.853462368700415 0.981473855698902 GO:0017171 serine hydrolase activity 12/1459 198/18639 0.0606060606060606 0.77425384759175 0.85796686110552 0.981473855698902 GO:0004843 cysteine-type deubiquitinase activity 6/1459 108/18639 0.0555555555555556 0.709732693625771 0.858292834414244 0.981473855698902 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/1459 60/18639 0.05 0.638759424263194 0.858650465066571 0.981473855698902 GO:0004806 triacylglycerol lipase activity 1/1459 24/18639 0.0416666666666667 0.532299520219328 0.85878962373654 0.981473855698902 GO:0015295 solute:proton symporter activity 1/1459 24/18639 0.0416666666666667 0.532299520219328 0.85878962373654 0.981473855698902 GO:0030552 cAMP binding 1/1459 24/18639 0.0416666666666667 0.532299520219328 0.85878962373654 0.981473855698902 GO:0043998 histone H2A acetyltransferase activity 1/1459 24/18639 0.0416666666666667 0.532299520219328 0.85878962373654 0.981473855698902 GO:0140101 catalytic activity, acting on a tRNA 8/1459 139/18639 0.0575539568345324 0.735262646633892 0.860399922974279 0.982346368750161 GO:0003954 NADH dehydrogenase activity 2/1459 44/18639 0.0454545454545455 0.580690385693813 0.869117586640274 0.987313639306512 GO:0030547 signaling receptor inhibitor activity 2/1459 44/18639 0.0454545454545455 0.580690385693813 0.869117586640274 0.987313639306512 GO:0005537 D-mannose binding 1/1459 25/18639 0.04 0.511007539410555 0.869857361526945 0.987313639306512 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1459 25/18639 0.04 0.511007539410555 0.869857361526945 0.987313639306512 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1459 25/18639 0.04 0.511007539410555 0.869857361526945 0.987313639306512 GO:0019707 protein-cysteine S-acyltransferase activity 1/1459 25/18639 0.04 0.511007539410555 0.869857361526945 0.987313639306512 GO:0015179 L-amino acid transmembrane transporter activity 3/1459 62/18639 0.0483870967741935 0.618154281545026 0.873317277488325 0.988338702162319 GO:0019783 ubiquitin-like protein peptidase activity 7/1459 127/18639 0.0551181102362205 0.704144247219269 0.877143038333194 0.988338702162319 GO:0008009 chemokine activity 2/1459 45/18639 0.0444444444444444 0.567786154900617 0.877217564137718 0.988338702162319 GO:0022843 voltage-gated monoatomic cation channel activity 8/1459 143/18639 0.0559440559440559 0.714695859315462 0.879921329770408 0.988338702162319 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1459 26/18639 0.0384615384615385 0.49135340327938 0.880058184001006 0.988338702162319 GO:0004950 chemokine receptor activity 1/1459 26/18639 0.0384615384615385 0.49135340327938 0.880058184001006 0.988338702162319 GO:0005227 calcium-activated cation channel activity 1/1459 26/18639 0.0384615384615385 0.49135340327938 0.880058184001006 0.988338702162319 GO:0008066 glutamate receptor activity 1/1459 26/18639 0.0384615384615385 0.49135340327938 0.880058184001006 0.988338702162319 GO:0030507 spectrin binding 1/1459 26/18639 0.0384615384615385 0.49135340327938 0.880058184001006 0.988338702162319 GO:0051139 metal cation:proton antiporter activity 1/1459 26/18639 0.0384615384615385 0.49135340327938 0.880058184001006 0.988338702162319 GO:0005507 copper ion binding 3/1459 63/18639 0.0476190476190476 0.60834230882209 0.880132654597996 0.988338702162319 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1459 46/18639 0.0434782608695652 0.555442977620169 0.884852503984902 0.992677857468556 GO:0015101 organic cation transmembrane transporter activity 4/1459 81/18639 0.0493827160493827 0.63087350544513 0.887194521966161 0.994343618821977 GO:0008395 steroid hydroxylase activity 1/1459 27/18639 0.037037037037037 0.473155129083847 0.889459952095485 0.994960023559077 GO:0015252 proton channel activity 1/1459 27/18639 0.037037037037037 0.473155129083847 0.889459952095485 0.994960023559077 GO:0016298 lipase activity 7/1459 130/18639 0.0538461538461538 0.687894764591132 0.891195113266512 0.995931473700918 GO:0099095 ligand-gated monoatomic anion channel activity 2/1459 47/18639 0.0425531914893617 0.543625041926122 0.892045518254529 0.995931473700918 GO:0005254 chloride channel activity 4/1459 83/18639 0.0481927710843374 0.615671734229585 0.898048848951219 0.998873684501163 GO:0036408 histone H3K14 acetyltransferase activity 1/1459 28/18639 0.0357142857142857 0.456256731616567 0.898125218047166 0.998873684501163 GO:0050698 proteoglycan sulfotransferase activity 1/1459 28/18639 0.0357142857142857 0.456256731616567 0.898125218047166 0.998873684501163 GO:0051537 2 iron, 2 sulfur cluster binding 1/1459 28/18639 0.0357142857142857 0.456256731616567 0.898125218047166 0.998873684501163 GO:0008514 organic anion transmembrane transporter activity 16/1459 269/18639 0.0594795539033457 0.759862512134654 0.902194783587963 0.999999992535004 GO:0008173 RNA methyltransferase activity 3/1459 67/18639 0.0447761194029851 0.572023365011815 0.904236790227579 0.999999992535004 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/1459 67/18639 0.0447761194029851 0.572023365011815 0.904236790227579 0.999999992535004 GO:0010484 histone H3 acetyltransferase activity 1/1459 29/18639 0.0344827586206897 0.440523740871168 0.906111640424748 0.999999992535004 GO:0016417 S-acyltransferase activity 1/1459 29/18639 0.0344827586206897 0.440523740871168 0.906111640424748 0.999999992535004 GO:0035250 UDP-galactosyltransferase activity 1/1459 29/18639 0.0344827586206897 0.440523740871168 0.906111640424748 0.999999992535004 GO:0099604 ligand-gated calcium channel activity 1/1459 29/18639 0.0344827586206897 0.440523740871168 0.906111640424748 0.999999992535004 GO:0015103 inorganic anion transmembrane transporter activity 9/1459 165/18639 0.0545454545454545 0.696828462832575 0.906562556720628 0.999999992535004 GO:0005253 monoatomic anion channel activity 5/1459 103/18639 0.0485436893203883 0.620154780838052 0.913428514557573 0.999999992535004 GO:0022839 monoatomic ion-gated channel activity 1/1459 30/18639 0.0333333333333333 0.425839616175463 0.913472366734275 0.999999992535004 GO:0031624 ubiquitin conjugating enzyme binding 1/1459 30/18639 0.0333333333333333 0.425839616175463 0.913472366734275 0.999999992535004 GO:0043995 histone H4K5 acetyltransferase activity 1/1459 30/18639 0.0333333333333333 0.425839616175463 0.913472366734275 0.999999992535004 GO:0043996 histone H4K8 acetyltransferase activity 1/1459 30/18639 0.0333333333333333 0.425839616175463 0.913472366734275 0.999999992535004 GO:0043997 histone H4K12 acetyltransferase activity 1/1459 30/18639 0.0333333333333333 0.425839616175463 0.913472366734275 0.999999992535004 GO:0048019 receptor antagonist activity 1/1459 30/18639 0.0333333333333333 0.425839616175463 0.913472366734275 0.999999992535004 GO:0016782 transferase activity, transferring sulphur-containing groups 3/1459 70/18639 0.0428571428571429 0.547508077939881 0.919340379941019 0.999999992535004 GO:0015108 chloride transmembrane transporter activity 6/1459 121/18639 0.0495867768595041 0.633480420756887 0.919432691692993 0.999999992535004 GO:0005184 neuropeptide hormone activity 1/1459 31/18639 0.032258064516129 0.412102854363351 0.920256386129981 0.999999992535004 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1459 31/18639 0.032258064516129 0.412102854363351 0.920256386129981 0.999999992535004 GO:0008327 methyl-CpG binding 1/1459 31/18639 0.032258064516129 0.412102854363351 0.920256386129981 0.999999992535004 GO:0016411 acylglycerol O-acyltransferase activity 1/1459 31/18639 0.032258064516129 0.412102854363351 0.920256386129981 0.999999992535004 GO:0047499 calcium-independent phospholipase A2 activity 1/1459 31/18639 0.032258064516129 0.412102854363351 0.920256386129981 0.999999992535004 GO:0072349 modified amino acid transmembrane transporter activity 1/1459 31/18639 0.032258064516129 0.412102854363351 0.920256386129981 0.999999992535004 GO:0008017 microtubule binding 16/1459 276/18639 0.0579710144927536 0.740590636826892 0.921030865051705 0.999999992535004 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 6/1459 122/18639 0.0491803278688525 0.628287958291666 0.923003393463706 0.999999992535004 GO:0008378 galactosyltransferase activity 1/1459 32/18639 0.03125 0.399224640164496 0.926508854564867 0.999999992535004 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1459 32/18639 0.03125 0.399224640164496 0.926508854564867 0.999999992535004 GO:0042910 xenobiotic transmembrane transporter activity 1/1459 32/18639 0.03125 0.399224640164496 0.926508854564867 0.999999992535004 GO:0043425 bHLH transcription factor binding 1/1459 32/18639 0.03125 0.399224640164496 0.926508854564867 0.999999992535004 GO:0047498 calcium-dependent phospholipase A2 activity 1/1459 32/18639 0.03125 0.399224640164496 0.926508854564867 0.999999992535004 GO:0160041 neuropeptide activity 1/1459 32/18639 0.03125 0.399224640164496 0.926508854564867 0.999999992535004 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/1459 53/18639 0.0377358490566038 0.48208258434958 0.927118815144269 0.999999992535004 GO:0042379 chemokine receptor binding 3/1459 72/18639 0.0416666666666667 0.532299520219328 0.928165643612734 0.999999992535004 GO:0008168 methyltransferase activity 11/1459 204/18639 0.053921568627451 0.688858202636778 0.930740547785258 0.999999992535004 GO:0003684 damaged DNA binding 3/1459 74/18639 0.0405405405405405 0.517913046699887 0.936095603681709 0.999999992535004 GO:0140098 catalytic activity, acting on RNA 23/1459 387/18639 0.0594315245478036 0.759248928064778 0.936687503526527 0.999999992535004 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1459 34/18639 0.0294117647058824 0.375740837801879 0.937582371388796 0.999999992535004 GO:0015079 potassium ion transmembrane transporter activity 8/1459 160/18639 0.05 0.638759424263194 0.939395252950987 0.999999992535004 GO:0051213 dioxygenase activity 4/1459 93/18639 0.043010752688172 0.549470472484468 0.939599052999276 0.999999992535004 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1459 56/18639 0.0357142857142857 0.456256731616567 0.940319690076094 0.999999992535004 GO:0000175 3'-5'-RNA exonuclease activity 1/1459 35/18639 0.0285714285714286 0.365005385293254 0.94247714806946 0.999999992535004 GO:0004623 phospholipase A2 activity 1/1459 35/18639 0.0285714285714286 0.365005385293254 0.94247714806946 0.999999992535004 GO:0010485 histone H4 acetyltransferase activity 1/1459 35/18639 0.0285714285714286 0.365005385293254 0.94247714806946 0.999999992535004 GO:0004190 aspartic-type endopeptidase activity 1/1459 36/18639 0.0277777777777778 0.354866346812886 0.946988319912432 0.999999992535004 GO:0016409 palmitoyltransferase activity 1/1459 36/18639 0.0277777777777778 0.354866346812886 0.946988319912432 0.999999992535004 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/1459 58/18639 0.0344827586206897 0.440523740871168 0.947822020041603 0.999999992535004 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/1459 181/18639 0.0497237569060773 0.63523036667058 0.950513322037403 0.999999992535004 GO:0008509 monoatomic anion transmembrane transporter activity 7/1459 149/18639 0.0469798657718121 0.600176640247296 0.952139724972517 0.999999992535004 GO:0005249 voltage-gated potassium channel activity 4/1459 98/18639 0.0408163265306122 0.521436264704648 0.953970429263456 0.999999992535004 GO:0019842 vitamin binding 7/1459 150/18639 0.0466666666666667 0.596175462645648 0.954269199277652 0.999999992535004 GO:0016741 transferase activity, transferring one-carbon groups 11/1459 215/18639 0.0511627906976744 0.653614294594896 0.954307854883245 0.999999992535004 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/1459 38/18639 0.0263157894736842 0.336189170664839 0.954977674290248 0.999999992535004 GO:0042887 amide transmembrane transporter activity 1/1459 38/18639 0.0263157894736842 0.336189170664839 0.954977674290248 0.999999992535004 GO:0000217 DNA secondary structure binding 1/1459 39/18639 0.0256410256410256 0.327568935519587 0.958509074387583 0.999999992535004 GO:0031406 carboxylic acid binding 9/1459 187/18639 0.0481283422459893 0.614848643675802 0.961527024272429 0.999999992535004 GO:0004532 RNA exonuclease activity 1/1459 40/18639 0.025 0.319379712131597 0.96176365828374 0.999999992535004 GO:0022824 transmitter-gated monoatomic ion channel activity 2/1459 63/18639 0.0317460317460317 0.405561539214726 0.962840139497423 0.999999992535004 GO:0022835 transmitter-gated channel activity 2/1459 63/18639 0.0317460317460317 0.405561539214726 0.962840139497423 0.999999992535004 GO:1901682 sulfur compound transmembrane transporter activity 2/1459 63/18639 0.0317460317460317 0.405561539214726 0.962840139497423 0.999999992535004 GO:0015171 amino acid transmembrane transporter activity 4/1459 102/18639 0.0392156862745098 0.500987783735838 0.963122183599732 0.999999992535004 GO:0043177 organic acid binding 9/1459 189/18639 0.0476190476190476 0.60834230882209 0.964677405748132 0.999999992535004 GO:0004812 aminoacyl-tRNA ligase activity 1/1459 41/18639 0.024390243902439 0.311589963055217 0.964763111080343 0.999999992535004 GO:0008227 G protein-coupled amine receptor activity 1/1459 41/18639 0.024390243902439 0.311589963055217 0.964763111080343 0.999999992535004 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1459 41/18639 0.024390243902439 0.311589963055217 0.964763111080343 0.999999992535004 GO:0017080 sodium channel regulator activity 1/1459 41/18639 0.024390243902439 0.311589963055217 0.964763111080343 0.999999992535004 GO:0005244 voltage-gated monoatomic ion channel activity 8/1459 173/18639 0.046242774566474 0.590760161168272 0.965575405601223 0.999999992535004 GO:0015291 secondary active transmembrane transporter activity 15/1459 287/18639 0.0522648083623693 0.667692777975464 0.967325715839352 0.999999992535004 GO:0004402 histone acetyltransferase activity 1/1459 42/18639 0.0238095238095238 0.304171154411045 0.967527420196043 0.999999992535004 GO:0004520 DNA endonuclease activity 1/1459 42/18639 0.0238095238095238 0.304171154411045 0.967527420196043 0.999999992535004 GO:0022832 voltage-gated channel activity 8/1459 175/18639 0.0457142857142857 0.584008616469206 0.968537800432204 0.999999992535004 GO:0004518 nuclease activity 10/1459 209/18639 0.0478468899521531 0.611253037572434 0.96964832830376 0.999999992535004 GO:0005267 potassium channel activity 5/1459 124/18639 0.0403225806451613 0.515128567954189 0.970030789215804 0.999999992535004 GO:0004497 monooxygenase activity 4/1459 106/18639 0.0377358490566038 0.48208258434958 0.97055936132415 0.999999992535004 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/1459 88/18639 0.0340909090909091 0.43551778927036 0.972576855106708 0.999999992535004 GO:0046915 transition metal ion transmembrane transporter activity 1/1459 45/18639 0.0222222222222222 0.283893077450308 0.974586611818482 0.999999992535004 GO:0008080 N-acetyltransferase activity 2/1459 69/18639 0.0289855072463768 0.370295318413446 0.975420909923643 0.999999992535004 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1459 69/18639 0.0289855072463768 0.370295318413446 0.975420909923643 0.999999992535004 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/1459 70/18639 0.0285714285714286 0.365005385293254 0.977070337276073 0.999999992535004 GO:0061733 protein-lysine-acetyltransferase activity 1/1459 47/18639 0.0212765957446809 0.271812520963061 0.978418424513436 0.999999992535004 GO:0140299 molecular sensor activity 2/1459 71/18639 0.028169014084507 0.35986446437363 0.978612372864321 0.999999992535004 GO:0052689 carboxylic ester hydrolase activity 3/1459 92/18639 0.0326086956521739 0.416582233215126 0.978629156026216 0.999999992535004 GO:0015078 proton transmembrane transporter activity 8/1459 185/18639 0.0432432432432432 0.552440583146546 0.980156851736166 0.999999992535004 GO:0022804 active transmembrane transporter activity 25/1459 457/18639 0.0547045951859956 0.698861514511153 0.980803942742303 0.999999992535004 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/1459 73/18639 0.0273972602739726 0.350005163979832 0.981400645315046 0.999999992535004 GO:0035064 methylated histone binding 2/1459 74/18639 0.027027027027027 0.345275364466591 0.98265911869375 0.999999992535004 GO:0046943 carboxylic acid transmembrane transporter activity 8/1459 188/18639 0.0425531914893617 0.543625041926122 0.982778495709245 0.999999992535004 GO:0005342 organic acid transmembrane transporter activity 8/1459 189/18639 0.0423280423280423 0.540748718952968 0.983578543884322 0.999999992535004 GO:0005506 iron ion binding 6/1459 154/18639 0.038961038961039 0.497734616308982 0.983973180344924 0.999999992535004 GO:0016597 amino acid binding 1/1459 51/18639 0.0196078431372549 0.250493891867919 0.984436745279131 0.999999992535004 GO:0140034 methylation-dependent protein binding 2/1459 76/18639 0.0263157894736842 0.336189170664839 0.984932678530195 0.999999992535004 GO:0034212 protein N-acetyltransferase activity 1/1459 53/18639 0.0188679245283019 0.24104129217479 0.986784088357324 0.999999992535004 GO:0015370 solute:sodium symporter activity 2/1459 79/18639 0.0253164556962025 0.32342249329782 0.987808735082203 0.999999992535004 GO:0008374 O-acyltransferase activity 1/1459 55/18639 0.0181818181818182 0.232276154277525 0.988777596863007 0.999999992535004 GO:0030170 pyridoxal phosphate binding 1/1459 56/18639 0.0178571428571429 0.228128365808284 0.989658649713678 0.999999992535004 GO:0070279 vitamin B6 binding 1/1459 57/18639 0.0175438596491228 0.224126113776559 0.990470576209279 0.999999992535004 GO:0015081 sodium ion transmembrane transporter activity 6/1459 164/18639 0.0365853658536585 0.467384944582825 0.990572505493806 0.999999992535004 GO:0015293 symporter activity 5/1459 146/18639 0.0342465753424658 0.43750645497479 0.991060389730522 0.999999992535004 GO:0008408 3'-5' exonuclease activity 1/1459 58/18639 0.0172413793103448 0.220261870435584 0.991218796492922 0.999999992535004 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1459 60/18639 0.0166666666666667 0.212919808087731 0.992543708655017 0.999999992535004 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 9/1459 229/18639 0.0393013100436681 0.502081643525655 0.994440764471758 0.999999992535004 GO:0004536 DNA nuclease activity 1/1459 64/18639 0.015625 0.199612320082248 0.994624280279253 0.999999992535004 GO:0015294 solute:monoatomic cation symporter activity 3/1459 116/18639 0.0258620689655172 0.330392805653376 0.995471824523611 0.999999992535004 GO:0003777 microtubule motor activity 1/1459 68/18639 0.0147058823529412 0.187870418900939 0.99612458264938 0.999999992535004 GO:0005261 monoatomic cation channel activity 15/1459 341/18639 0.0439882697947214 0.561958437768206 0.996147117327246 0.999999992535004 GO:0016407 acetyltransferase activity 2/1459 96/18639 0.0208333333333333 0.266149760109664 0.996400069381665 0.999999992535004 GO:0030594 neurotransmitter receptor activity 2/1459 97/18639 0.0206185567010309 0.263405948149771 0.996652351552582 0.999999992535004 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/1459 130/18639 0.0230769230769231 0.294812041967628 0.99823188266638 0.999999992535004 GO:0003823 antigen binding 5/1459 174/18639 0.028735632183908 0.36710311739264 0.998280878561468 0.999999992535004 GO:0046873 metal ion transmembrane transporter activity 20/1459 450/18639 0.0444444444444444 0.567786154900617 0.998652147667692 0.999999992535004 GO:0004527 exonuclease activity 1/1459 84/18639 0.0119047619047619 0.152085577205522 0.998954011818811 0.999999992535004 GO:0022836 gated channel activity 12/1459 318/18639 0.0377358490566038 0.48208258434958 0.999003086876073 0.999999992535004 GO:0005216 monoatomic ion channel activity 19/1459 448/18639 0.0424107142857143 0.541804868794673 0.99928447881997 0.999999992535004 GO:0015276 ligand-gated monoatomic ion channel activity 4/1459 186/18639 0.021505376344086 0.274735236242234 0.99980509592563 0.999999992535004 GO:0099094 ligand-gated monoatomic cation channel activity 2/1459 136/18639 0.0147058823529412 0.187870418900939 0.999814131667656 0.999999992535004 GO:0022834 ligand-gated channel activity 4/1459 188/18639 0.0212765957446809 0.271812520963061 0.999829588863566 0.999999992535004 GO:0045182 translation regulator activity 9/1459 356/18639 0.0252808988764045 0.322968248222963 0.999995363831957 0.999999992535004 GO:0030371 translation repressor activity 4/1459 329/18639 0.0121580547112462 0.155321440550321 0.999999992535004 0.999999992535004