ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0005201	extracellular matrix structural constituent	30/621	168/18639	0.178571428571429	5.35973084886128	4.43559502034123e-14	4.02308468344949e-11
GO:0019838	growth factor binding	26/621	136/18639	0.191176470588235	5.73806479113385	4.25897778314876e-13	1.93144642465796e-10
GO:0005518	collagen binding	17/621	72/18639	0.236111111111111	7.08675523349436	1.52321048733333e-10	3.65523791120634e-08
GO:0003735	structural constituent of ribosome	26/621	175/18639	0.148571428571429	4.45929606625259	1.61201230924204e-10	3.65523791120634e-08
GO:0005539	glycosaminoglycan binding	30/621	242/18639	0.12396694214876	3.72080488681279	6.01339023628882e-10	1.09082898886279e-07
GO:0008201	heparin binding	23/621	172/18639	0.133720930232558	4.01356589147287	1.45406797147967e-08	2.19806608355343e-06
GO:0045296	cadherin binding	33/621	334/18639	0.0988023952095808	2.96550377505858	2.72612125303999e-08	3.53227425215325e-06
GO:0005178	integrin binding	21/621	161/18639	0.130434782608696	3.91493383742911	9.52194526026582e-08	1.07955054388264e-05
GO:1901681	sulfur compound binding	28/621	275/18639	0.101818181818182	3.05602108036891	1.65971061669125e-07	1.67261947704329e-05
GO:0043236	laminin binding	9/621	29/18639	0.310344827586207	9.31484257871064	2.63159999228133e-07	2.20130494332035e-05
GO:0050840	extracellular matrix binding	13/621	67/18639	0.194029850746269	5.82370754921047	2.66971933589017e-07	2.20130494332035e-05
GO:0048407	platelet-derived growth factor binding	6/621	11/18639	0.545454545454545	16.3715415019763	5.34856029251071e-07	4.04262015442268e-05
GO:0004857	enzyme inhibitor activity	33/621	416/18639	0.0793269230769231	2.38095735785953	4.08848305615543e-06	0.000285250317840998
GO:0001968	fibronectin binding	8/621	30/18639	0.266666666666667	8.00386473429952	4.43758669960345e-06	0.000287492224038595
GO:0008135	translation factor activity, RNA binding	11/621	83/18639	0.132530120481928	3.97782434084163	9.40710718192784e-05	0.00568816414267237
GO:0180051	translation factor activity	11/621	84/18639	0.130952380952381	3.93046928916494	0.000105044615293658	0.00595471662945923
GO:0019843	rRNA binding	9/621	65/18639	0.138461538461538	4.15585284280936	0.00028856090832277	0.0151262295850832
GO:0005520	insulin-like growth factor binding	5/621	19/18639	0.263157894736842	7.89855072463768	0.000318494619598354	0.0151262295850832
GO:0019955	cytokine binding	14/621	144/18639	0.0972222222222222	2.91807568438003	0.000329441235626747	0.0151262295850832
GO:0004864	protein phosphatase inhibitor activity	8/621	53/18639	0.150943396226415	4.53048947224501	0.000342348250335361	0.0151262295850832
GO:0001618	virus receptor activity	10/621	81/18639	0.123456790123457	3.70549293254607	0.000350221412664551	0.0151262295850832
GO:0140272	exogenous protein binding	10/621	82/18639	0.121951219512195	3.66030399434429	0.000387183889200869	0.0159625357956904
GO:0019212	phosphatase inhibitor activity	8/621	56/18639	0.142857142857143	4.28778467908903	0.000502711831766682	0.0198243318005383
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/621	44/18639	0.159090909090909	4.77503293807642	0.000577581478546093	0.0218277667100544
GO:0031994	insulin-like growth factor I binding	4/621	13/18639	0.307692307692308	9.23522853957637	0.000686215568391891	0.0248959008212578
GO:0051082	unfolded protein binding	12/621	121/18639	0.0991735537190083	2.97664390945023	0.000721129029425095	0.0251563088341754
GO:0004713	protein tyrosine kinase activity	13/621	140/18639	0.0928571428571429	2.78706004140787	0.000822333919364492	0.0273582626366587
GO:0003725	double-stranded RNA binding	9/621	75/18639	0.12	3.60173913043478	0.000844577016346684	0.0273582626366587
GO:0019903	protein phosphatase binding	13/621	144/18639	0.0902777777777778	2.70964170692432	0.00106875788555981	0.0323519649121594
GO:0008083	growth factor activity	14/621	162/18639	0.0864197530864197	2.59384505278225	0.00107007601694022	0.0323519649121594
GO:0005200	structural constituent of cytoskeleton	11/621	112/18639	0.0982142857142857	2.94785196687371	0.00128461420482619	0.0364585133727473
GO:0043394	proteoglycan binding	6/621	37/18639	0.162162162162162	4.86721504112808	0.00128629815648061	0.0364585133727473
GO:0038024	cargo receptor activity	8/621	65/18639	0.123076923076923	3.69409141583055	0.00137487390912601	0.0369919046769181
GO:0003743	translation initiation factor activity	7/621	51/18639	0.137254901960784	4.11963626030122	0.0014274715145448	0.0369919046769181
GO:0005021	vascular endothelial growth factor receptor activity	7/621	51/18639	0.137254901960784	4.11963626030122	0.0014274715145448	0.0369919046769181
GO:0140996	histone H3 kinase activity	23/621	357/18639	0.0644257703081232	1.93370681605976	0.00207230335213178	0.0522105316773202
GO:0035173	histone kinase activity	23/621	360/18639	0.0638888888888889	1.91759259259259	0.00230432074739316	0.0564869977806917
GO:0003746	translation elongation factor activity	4/621	18/18639	0.222222222222222	6.66988727858293	0.00257225198896604	0.0592686423537802
GO:0008525	phosphatidylcholine transporter activity	4/621	18/18639	0.222222222222222	6.66988727858293	0.00257225198896604	0.0592686423537802
GO:0005543	phospholipid binding	29/621	497/18639	0.0583501006036217	1.75134867174059	0.00261383207734422	0.0592686423537802
GO:0016504	peptidase activator activity	7/621	57/18639	0.12280701754386	3.68599033816425	0.00274597065044013	0.0607462287792488
GO:0019888	protein phosphatase regulator activity	10/621	107/18639	0.0934579439252336	2.80509278071245	0.00303483117884574	0.0655379018860258
GO:0035091	phosphatidylinositol binding	19/621	284/18639	0.0669014084507042	2.00801183915085	0.00324391762550627	0.0684240299147485
GO:0004714	transmembrane receptor protein tyrosine kinase activity	7/621	60/18639	0.116666666666667	3.50169082125604	0.00368237442815955	0.0744724226509061
GO:0005131	growth hormone receptor binding	3/621	10/18639	0.3	9.00434782608696	0.00370664089045929	0.0744724226509061
GO:0061134	peptidase regulator activity	16/621	226/18639	0.0707964601769911	2.12491984096447	0.00384866580487404	0.0744724226509061
GO:0120015	sterol transfer activity	5/621	32/18639	0.15625	4.68976449275362	0.00385910018146922	0.0744724226509061
GO:0019001	guanyl nucleotide binding	24/621	400/18639	0.06	1.80086956521739	0.00417526377696962	0.0772849846063561
GO:0032561	guanyl ribonucleotide binding	24/621	400/18639	0.06	1.80086956521739	0.00417526377696962	0.0772849846063561
GO:0019199	transmembrane receptor protein kinase activity	8/621	78/18639	0.102564102564103	3.07840951319212	0.00438454345028148	0.0795356181881061
GO:0051020	GTPase binding	20/621	315/18639	0.0634920634920635	1.90568207959512	0.00461916846230898	0.0800252820321413
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/621	21/18639	0.19047619047619	5.71704623878537	0.00464820526846543	0.0800252820321413
GO:0019902	phosphatase binding	14/621	190/18639	0.0736842105263158	2.21159420289855	0.00467622926979437	0.0800252820321413
GO:0038187	pattern recognition receptor activity	6/621	48/18639	0.125	3.7518115942029	0.0049874380885179	0.0824068241099174
GO:0035401	histone H3Y41 kinase activity	10/621	115/18639	0.0869565217391304	2.60995589161941	0.00508796267933338	0.0824068241099174
GO:0140801	histone H2AXY142 kinase activity	10/621	115/18639	0.0869565217391304	2.60995589161941	0.00508796267933338	0.0824068241099174
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/621	22/18639	0.181818181818182	5.45718050065876	0.00553358706878635	0.0880519907261266
GO:0019208	phosphatase regulator activity	10/621	117/18639	0.0854700854700855	2.56534126099343	0.0057410728702842	0.0887118427213999
GO:0002020	protease binding	11/621	136/18639	0.0808823529411765	2.42764279624893	0.00584661948783381	0.0887118427213999
GO:0022804	active transmembrane transporter activity	26/621	457/18639	0.0568927789934354	1.70760790283195	0.00586847912159205	0.0887118427213999
GO:0015368	calcium:monoatomic cation antiporter activity	3/621	12/18639	0.25	7.5036231884058	0.00646586538048082	0.0961399983622312
GO:0004860	protein kinase inhibitor activity	8/621	84/18639	0.0952380952380952	2.85852311939268	0.00685865703516268	0.100335515014396
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	7/621	68/18639	0.102941176470588	3.08972719522592	0.00736363967079076	0.106013034625511
GO:0050431	transforming growth factor beta binding	4/621	24/18639	0.166666666666667	5.0024154589372	0.00762689312275381	0.106245465913793
GO:0016209	antioxidant activity	8/621	86/18639	0.0930232558139535	2.79204583754634	0.00788152923227177	0.106245465913793
GO:0050660	flavin adenine dinucleotide binding	8/621	86/18639	0.0930232558139535	2.79204583754634	0.00788152923227177	0.106245465913793
GO:0141003	histone H2AX kinase activity	21/621	354/18639	0.0593220338983051	1.78052075657087	0.00801961058504085	0.106245465913793
GO:0005246	calcium channel regulator activity	6/621	53/18639	0.113207547169811	3.39786710418376	0.00811634948144717	0.106245465913793
GO:0043531	ADP binding	5/621	38/18639	0.131578947368421	3.94927536231884	0.00816877420923004	0.106245465913793
GO:0008035	high-density lipoprotein particle binding	3/621	13/18639	0.230769230769231	6.92642140468227	0.00819976032410751	0.106245465913793
GO:0120020	cholesterol transfer activity	4/621	25/18639	0.16	4.80231884057971	0.0088446917429581	0.111868321816953
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/621	54/18639	0.111111111111111	3.33494363929147	0.00888039599869971	0.111868321816953
GO:0015078	proton transmembrane transporter activity	13/621	185/18639	0.0702702702702703	2.10912651782217	0.00921820303097544	0.114533015741024
GO:0005516	calmodulin binding	14/621	207/18639	0.0676328502415459	2.02996569348176	0.00971215989934973	0.117860377988255
GO:0015036	disulfide oxidoreductase activity	5/621	40/18639	0.125	3.7518115942029	0.0101430044657666	0.117860377988255
GO:0015144	carbohydrate transmembrane transporter activity	5/621	40/18639	0.125	3.7518115942029	0.0101430044657666	0.117860377988255
GO:0005161	platelet-derived growth factor receptor binding	3/621	14/18639	0.214285714285714	6.43167701863354	0.0101809193192696	0.117860377988255
GO:0019992	diacylglycerol binding	3/621	14/18639	0.214285714285714	6.43167701863354	0.0101809193192696	0.117860377988255
GO:0019210	kinase inhibitor activity	8/621	90/18639	0.0888888888888889	2.66795491143317	0.010265677906364	0.117860377988255
GO:0042169	SH2 domain binding	5/621	41/18639	0.121951219512195	3.66030399434429	0.0112429756037454	0.127467235907463
GO:0005044	scavenger receptor activity	4/621	27/18639	0.148148148148148	4.44659151905529	0.0116450563839023	0.130395878274066
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/621	15/18639	0.2	6.00289855072464	0.0124155780233518	0.135673846592531
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/621	15/18639	0.2	6.00289855072464	0.0124155780233518	0.135673846592531
GO:0051019	mitogen-activated protein kinase binding	4/621	28/18639	0.142857142857143	4.28778467908903	0.0132356881861565	0.141319665044626
GO:0098631	cell adhesion mediator activity	7/621	76/18639	0.0921052631578947	2.76449275362319	0.0132438495356044	0.141319665044626
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/621	16/18639	0.1875	5.62771739130435	0.0149084696164391	0.155032075011373
GO:0140328	floppase activity	3/621	16/18639	0.1875	5.62771739130435	0.0149084696164391	0.155032075011373
GO:0004252	serine-type endopeptidase activity	12/621	176/18639	0.0681818181818182	2.04644268774704	0.0150417007728785	0.155032075011373
GO:0005525	GTP binding	21/621	378/18639	0.0555555555555556	1.66747181964573	0.0158911527726381	0.161946916458233
GO:0008569	minus-end-directed microtubule motor activity	3/621	17/18639	0.176470588235294	5.29667519181586	0.0176629445366092	0.174133594507659
GO:0030169	low-density lipoprotein particle binding	3/621	17/18639	0.176470588235294	5.29667519181586	0.0176629445366092	0.174133594507659
GO:0045236	CXCR chemokine receptor binding	3/621	17/18639	0.176470588235294	5.29667519181586	0.0176629445366092	0.174133594507659
GO:0070851	growth factor receptor binding	10/621	139/18639	0.0719424460431655	2.15931602544052	0.0180263256873905	0.175805133316809
GO:0106310	protein serine kinase activity	20/621	361/18639	0.0554016620498615	1.66285278413425	0.0187955830776693	0.181357381398363
GO:0001784	phosphotyrosine residue binding	5/621	47/18639	0.106382978723404	3.19303114400247	0.0195714210684679	0.185059400151639
GO:0015373	monoatomic anion:sodium symporter activity	3/621	18/18639	0.166666666666667	5.0024154589372	0.0206810830461379	0.185059400151639
GO:0098641	cadherin binding involved in cell-cell adhesion	3/621	18/18639	0.166666666666667	5.0024154589372	0.0206810830461379	0.185059400151639
GO:0051059	NF-kappaB binding	4/621	32/18639	0.125	3.7518115942029	0.0209470791355792	0.185059400151639
GO:0071813	lipoprotein particle binding	4/621	32/18639	0.125	3.7518115942029	0.0209470791355792	0.185059400151639
GO:0071814	protein-lipid complex binding	4/621	32/18639	0.125	3.7518115942029	0.0209470791355792	0.185059400151639
GO:1901981	phosphatidylinositol phosphate binding	12/621	185/18639	0.0648648648648649	1.94688601645123	0.0213887427059076	0.185059400151639
GO:0015081	sodium ion transmembrane transporter activity	11/621	164/18639	0.0670731707317073	2.01316719688936	0.0216304312042599	0.185059400151639
GO:0005126	cytokine receptor binding	16/621	275/18639	0.0581818181818182	1.7462977602108	0.0223881578394209	0.185059400151639
GO:0005004	GPI-linked ephrin receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0005008	hepatocyte growth factor receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0005009	insulin receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0005011	macrophage colony-stimulating factor receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0005020	stem cell factor receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0008288	boss receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0036332	placental growth factor receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0038062	protein tyrosine kinase collagen receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0060175	brain-derived neurotrophic factor receptor activity	5/621	49/18639	0.102040816326531	3.06270334220645	0.0230559120365327	0.185059400151639
GO:0015399	primary active transmembrane transporter activity	11/621	166/18639	0.0662650602409639	1.98891217042081	0.0234100266741776	0.186253457837536
GO:0043395	heparan sulfate proteoglycan binding	3/621	19/18639	0.157894736842105	4.73913043478261	0.0239638010008892	0.186939794479974
GO:0097001	ceramide binding	3/621	19/18639	0.157894736842105	4.73913043478261	0.0239638010008892	0.186939794479974
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	7/621	86/18639	0.0813953488372093	2.44304010785305	0.0245745441723273	0.186939794479974
GO:0005006	epidermal growth factor receptor activity	5/621	50/18639	0.1	3.00144927536232	0.0249390464521244	0.186939794479974
GO:0005007	fibroblast growth factor receptor activity	5/621	50/18639	0.1	3.00144927536232	0.0249390464521244	0.186939794479974
GO:0005017	platelet-derived growth factor receptor activity	5/621	50/18639	0.1	3.00144927536232	0.0249390464521244	0.186939794479974
GO:0005019	platelet-derived growth factor beta-receptor activity	5/621	50/18639	0.1	3.00144927536232	0.0249390464521244	0.186939794479974
GO:0031625	ubiquitin protein ligase binding	17/621	302/18639	0.0562913907284768	1.68955753911124	0.0251540814107186	0.187006162619031
GO:0032934	sterol binding	6/621	68/18639	0.0882352941176471	2.64833759590793	0.0255539018494036	0.187613302619154
GO:0015035	protein-disulfide reductase activity	4/621	34/18639	0.117647058823529	3.5311167945439	0.0256494482081313	0.187613302619154
GO:0030246	carbohydrate binding	16/621	280/18639	0.0571428571428571	1.71511387163561	0.0259214000574281	0.188085678816698
GO:0005010	insulin-like growth factor receptor activity	5/621	51/18639	0.0980392156862745	2.94259732878659	0.0269181022548448	0.192241879883025
GO:0005030	neurotrophin receptor activity	5/621	51/18639	0.0980392156862745	2.94259732878659	0.0269181022548448	0.192241879883025
GO:0016651	oxidoreductase activity, acting on NAD(P)H	7/621	88/18639	0.0795454545454545	2.38751646903821	0.0274535546717383	0.193429696929794
GO:0043024	ribosomal small subunit binding	3/621	20/18639	0.15	4.50217391304348	0.0275109491774459	0.193429696929794
GO:0005496	steroid binding	8/621	108/18639	0.0740740740740741	2.22329575952764	0.0279039439027438	0.19468367015222
GO:0031267	small GTPase binding	16/621	283/18639	0.0565371024734982	1.69693245250166	0.0282326992192956	0.195473726655734
GO:0008236	serine-type peptidase activity	12/621	194/18639	0.0618556701030928	1.85656656207979	0.0295331394756886	0.2029284659428
GO:0045505	dynein intermediate chain binding	4/621	36/18639	0.111111111111111	3.33494363929147	0.0309370576580273	0.207871198722258
GO:0005003	ephrin receptor activity	5/621	53/18639	0.0943396226415094	2.83155592015313	0.0311692205360828	0.207871198722258
GO:0005005	transmembrane-ephrin receptor activity	5/621	53/18639	0.0943396226415094	2.83155592015313	0.0311692205360828	0.207871198722258
GO:0038064	collagen receptor activity	5/621	53/18639	0.0943396226415094	2.83155592015313	0.0311692205360828	0.207871198722258
GO:1902936	phosphatidylinositol bisphosphate binding	8/621	111/18639	0.0720720720720721	2.16320668494582	0.032146013732706	0.212820689456674
GO:0015485	cholesterol binding	5/621	54/18639	0.0925925925925926	2.77911969940955	0.0334435903868362	0.216404104068798
GO:0004674	protein serine/threonine kinase activity	22/621	433/18639	0.0508083140877598	1.52498577501088	0.03358913743371	0.216404104068798
GO:0043022	ribosome binding	8/621	112/18639	0.0714285714285714	2.14389233954451	0.0336526812112282	0.216404104068798
GO:0017171	serine hydrolase activity	12/621	198/18639	0.0606060606060606	1.81906016688625	0.0337926026823021	0.216404104068798
GO:0043178	alcohol binding	7/621	92/18639	0.0760869565217391	2.28371140516698	0.0338802456204734	0.216404104068798
GO:0043021	ribonucleoprotein complex binding	11/621	177/18639	0.0621468926553672	1.86530745926472	0.035147881375826	0.222930967887232
GO:0000146	microfilament motor activity	4/621	38/18639	0.105263157894737	3.15942028985507	0.0368192913821982	0.231910397803151
GO:0042562	hormone binding	7/621	94/18639	0.074468085106383	2.23512180080173	0.0374395482852457	0.234190829618744
GO:0035403	histone H3T6 kinase activity	14/621	247/18639	0.0566801619433198	1.70122630992196	0.0377147838705703	0.234296636784981
GO:0004867	serine-type endopeptidase inhibitor activity	7/621	95/18639	0.0736842105263158	2.21159420289855	0.0393079474387	0.241209666889374
GO:0099186	structural constituent of postsynapse	3/621	23/18639	0.130434782608696	3.91493383742911	0.0397234241109655	0.241209666889374
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/621	39/18639	0.102564102564103	3.07840951319212	0.0399850253340666	0.241209666889374
GO:0009055	electron transfer activity	8/621	116/18639	0.0689655172413793	2.06996501749125	0.0401572874314172	0.241209666889374
GO:0015294	solute:monoatomic cation symporter activity	8/621	116/18639	0.0689655172413793	2.06996501749125	0.0401572874314172	0.241209666889374
GO:0005345	purine nucleobase transmembrane transporter activity	2/621	10/18639	0.2	6.00289855072464	0.0417690335278447	0.24761119875657
GO:0005522	profilin binding	2/621	10/18639	0.2	6.00289855072464	0.0417690335278447	0.24761119875657
GO:0044389	ubiquitin-like protein ligase binding	17/621	322/18639	0.0527950310559006	1.58461607705464	0.0422806122343178	0.249016333094326
GO:0071949	FAD binding	4/621	40/18639	0.1	3.00144927536232	0.0433008054305444	0.249050499416299
GO:0022853	active monoatomic ion transmembrane transporter activity	8/621	118/18639	0.0677966101694915	2.03488086465242	0.0437032624477675	0.249050499416299
GO:0005540	hyaluronic acid binding	3/621	24/18639	0.125	3.7518115942029	0.0443086428235672	0.249050499416299
GO:0015149	hexose transmembrane transporter activity	3/621	24/18639	0.125	3.7518115942029	0.0443086428235672	0.249050499416299
GO:0048027	mRNA 5'-UTR binding	3/621	24/18639	0.125	3.7518115942029	0.0443086428235672	0.249050499416299
GO:0055056	D-glucose transmembrane transporter activity	3/621	24/18639	0.125	3.7518115942029	0.0443086428235672	0.249050499416299
GO:0070300	phosphatidic acid binding	3/621	24/18639	0.125	3.7518115942029	0.0443086428235672	0.249050499416299
GO:0061135	endopeptidase regulator activity	11/621	184/18639	0.0597826086956522	1.79434467548834	0.0444831101493279	0.249050499416299
GO:0045309	protein phosphorylated amino acid binding	5/621	59/18639	0.0847457627118644	2.54360108081552	0.0463383209537924	0.255525486169857
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	4/621	41/18639	0.0975609756097561	2.92824319547543	0.0467665167631712	0.255525486169857
GO:0008137	NADH dehydrogenase (ubiquinone) activity	4/621	41/18639	0.0975609756097561	2.92824319547543	0.0467665167631712	0.255525486169857
GO:0140828	metal cation:monoatomic cation antiporter activity	4/621	41/18639	0.0975609756097561	2.92824319547543	0.0467665167631712	0.255525486169857
GO:0015370	solute:sodium symporter activity	6/621	79/18639	0.0759493670886076	2.27958172812328	0.0480283331740737	0.256029470077221
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/621	25/18639	0.12	3.60173913043478	0.0491446361527412	0.256029470077221
GO:0015173	aromatic amino acid transmembrane transporter activity	2/621	11/18639	0.181818181818182	5.45718050065876	0.0499462922988089	0.256029470077221
GO:0015205	nucleobase transmembrane transporter activity	2/621	11/18639	0.181818181818182	5.45718050065876	0.0499462922988089	0.256029470077221
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/621	11/18639	0.181818181818182	5.45718050065876	0.0499462922988089	0.256029470077221
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/621	11/18639	0.181818181818182	5.45718050065876	0.0499462922988089	0.256029470077221
GO:0050786	RAGE receptor binding	2/621	11/18639	0.181818181818182	5.45718050065876	0.0499462922988089	0.256029470077221
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/621	11/18639	0.181818181818182	5.45718050065876	0.0499462922988089	0.256029470077221
GO:1990948	ubiquitin ligase inhibitor activity	2/621	11/18639	0.181818181818182	5.45718050065876	0.0499462922988089	0.256029470077221
GO:0008307	structural constituent of muscle	4/621	42/18639	0.0952380952380952	2.85852311939268	0.0503817826581325	0.256029470077221
GO:0035198	miRNA binding	4/621	42/18639	0.0952380952380952	2.85852311939268	0.0503817826581325	0.256029470077221
GO:0042056	chemoattractant activity	4/621	42/18639	0.0952380952380952	2.85852311939268	0.0503817826581325	0.256029470077221
GO:0048306	calcium-dependent protein binding	6/621	80/18639	0.075	2.25108695652174	0.05052841801965	0.256029470077221
GO:0015026	coreceptor activity	5/621	61/18639	0.0819672131147541	2.46020432406747	0.0522172476739209	0.263116909112479
GO:0004175	endopeptidase activity	20/621	405/18639	0.0493827160493827	1.48219717301843	0.0525599726347373	0.263380636351971
GO:0004712	protein serine/threonine/tyrosine kinase activity	4/621	43/18639	0.0930232558139535	2.79204583754634	0.0541459742815938	0.267301921039494
GO:0005112	Notch binding	3/621	26/18639	0.115384615384615	3.46321070234114	0.054226630067549	0.267301921039494
GO:0015145	monosaccharide transmembrane transporter activity	3/621	26/18639	0.115384615384615	3.46321070234114	0.054226630067549	0.267301921039494
GO:0015293	symporter activity	9/621	146/18639	0.0616438356164384	1.85020845741513	0.0556966418536728	0.273064076547466
GO:0015291	secondary active transmembrane transporter activity	15/621	287/18639	0.0522648083623693	1.56870171186184	0.0579553498829761	0.275588790455981
GO:0019207	kinase regulator activity	15/621	287/18639	0.0522648083623693	1.56870171186184	0.0579553498829761	0.275588790455981
GO:0003954	NADH dehydrogenase activity	4/621	44/18639	0.0909090909090909	2.72859025032938	0.0580582205328347	0.275588790455981
GO:0019205	nucleobase-containing compound kinase activity	4/621	44/18639	0.0909090909090909	2.72859025032938	0.0580582205328347	0.275588790455981
GO:0004859	phospholipase inhibitor activity	2/621	12/18639	0.166666666666667	5.0024154589372	0.0586423776824745	0.275588790455981
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/621	12/18639	0.166666666666667	5.0024154589372	0.0586423776824745	0.275588790455981
GO:0070679	inositol 1,4,5 trisphosphate binding	2/621	12/18639	0.166666666666667	5.0024154589372	0.0586423776824745	0.275588790455981
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/621	12/18639	0.166666666666667	5.0024154589372	0.0586423776824745	0.275588790455981
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/621	27/18639	0.111111111111111	3.33494363929147	0.0595493267780049	0.278408450451806
GO:0008009	chemokine activity	4/621	45/18639	0.0888888888888889	2.66795491143317	0.0621174181621629	0.28892563216965
GO:0008013	beta-catenin binding	7/621	106/18639	0.0660377358490566	1.98208914410719	0.0639103769465471	0.294298149599669
GO:0046625	sphingolipid binding	3/621	28/18639	0.107142857142857	3.21583850931677	0.0651069634090266	0.294298149599669
GO:0046875	ephrin receptor binding	3/621	28/18639	0.107142857142857	3.21583850931677	0.0651069634090266	0.294298149599669
GO:0051119	sugar transmembrane transporter activity	3/621	28/18639	0.107142857142857	3.21583850931677	0.0651069634090266	0.294298149599669
GO:0051959	dynein light intermediate chain binding	3/621	28/18639	0.107142857142857	3.21583850931677	0.0651069634090266	0.294298149599669
GO:0120013	lipid transfer activity	5/621	65/18639	0.0769230769230769	2.30880713489409	0.0652193253247336	0.294298149599669
GO:0004535	poly(A)-specific ribonuclease activity	2/621	13/18639	0.153846153846154	4.61761426978818	0.067813762656723	0.297135665360617
GO:0017154	semaphorin receptor activity	2/621	13/18639	0.153846153846154	4.61761426978818	0.067813762656723	0.297135665360617
GO:0031432	titin binding	2/621	13/18639	0.153846153846154	4.61761426978818	0.067813762656723	0.297135665360617
GO:0035325	Toll-like receptor binding	2/621	13/18639	0.153846153846154	4.61761426978818	0.067813762656723	0.297135665360617
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/621	13/18639	0.153846153846154	4.61761426978818	0.067813762656723	0.297135665360617
GO:1901338	catecholamine binding	2/621	13/18639	0.153846153846154	4.61761426978818	0.067813762656723	0.297135665360617
GO:0046982	protein heterodimerization activity	18/621	369/18639	0.0487804878048781	1.46412159773772	0.0695187517725291	0.303141864700403
GO:0016500	protein-hormone receptor activity	5/621	67/18639	0.0746268656716418	2.2398875189271	0.0723392839654042	0.3139317251513
GO:0005548	phospholipid transporter activity	5/621	68/18639	0.0735294117647059	2.20694799658994	0.0760524095301662	0.328127324988284
GO:0031210	phosphatidylcholine binding	3/621	30/18639	0.1	3.00144927536232	0.0769020042698791	0.328127324988284
GO:0098918	structural constituent of synapse	3/621	30/18639	0.1	3.00144927536232	0.0769020042698791	0.328127324988284
GO:0004065	arylsulfatase activity	2/621	14/18639	0.142857142857143	4.28778467908903	0.0774192365462986	0.328127324988284
GO:1901474	azole transmembrane transporter activity	2/621	14/18639	0.142857142857143	4.28778467908903	0.0774192365462986	0.328127324988284
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/621	31/18639	0.0967741935483871	2.90462833099579	0.0831260316809753	0.349052364512244
GO:0017147	Wnt-protein binding	3/621	31/18639	0.0967741935483871	2.90462833099579	0.0831260316809753	0.349052364512244
GO:0097110	scaffold protein binding	5/621	70/18639	0.0714285714285714	2.14389233954451	0.0837814907165888	0.350183465806203
GO:0019887	protein kinase regulator activity	13/621	255/18639	0.0509803921568627	1.53015061096903	0.0856434945705549	0.356324080621529
GO:0004129	cytochrome-c oxidase activity	2/621	15/18639	0.133333333333333	4.00193236714976	0.0874197993959828	0.357161072307011
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/621	15/18639	0.133333333333333	4.00193236714976	0.0874197993959828	0.357161072307011
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/621	15/18639	0.133333333333333	4.00193236714976	0.0874197993959828	0.357161072307011
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/621	15/18639	0.133333333333333	4.00193236714976	0.0874197993959828	0.357161072307011
GO:0003924	GTPase activity	16/621	331/18639	0.0483383685800604	1.45085161346819	0.0885766191948942	0.360264545335287
GO:0001221	transcription coregulator binding	7/621	115/18639	0.0608695652173913	1.82696912413359	0.089712135525836	0.36117635018796
GO:0017124	SH3 domain binding	7/621	115/18639	0.0608695652173913	1.82696912413359	0.089712135525836	0.36117635018796
GO:0004866	endopeptidase inhibitor activity	9/621	161/18639	0.0559006211180124	1.67782878746962	0.0899954301460628	0.36117635018796
GO:0042379	chemokine receptor binding	5/621	72/18639	0.0694444444444444	2.08433977455717	0.0919085590238057	0.367229352575294
GO:0019956	chemokine binding	3/621	33/18639	0.0909090909090909	2.72859025032938	0.096191582238555	0.377383636763003
GO:0004708	MAP kinase kinase activity	2/621	16/18639	0.125	3.7518115942029	0.0977785607930604	0.377383636763003
GO:0015378	sodium:chloride symporter activity	2/621	16/18639	0.125	3.7518115942029	0.0977785607930604	0.377383636763003
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/621	16/18639	0.125	3.7518115942029	0.0977785607930604	0.377383636763003
GO:0022858	alanine transmembrane transporter activity	2/621	16/18639	0.125	3.7518115942029	0.0977785607930604	0.377383636763003
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/621	16/18639	0.125	3.7518115942029	0.0977785607930604	0.377383636763003
GO:0055102	lipase inhibitor activity	2/621	16/18639	0.125	3.7518115942029	0.0977785607930604	0.377383636763003
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/621	16/18639	0.125	3.7518115942029	0.0977785607930604	0.377383636763003
GO:0030332	cyclin binding	3/621	34/18639	0.0882352941176471	2.64833759590793	0.103018240370532	0.39248482163244
GO:0051427	hormone receptor binding	3/621	34/18639	0.0882352941176471	2.64833759590793	0.103018240370532	0.39248482163244
GO:0016887	ATP hydrolysis activity	19/621	417/18639	0.0455635491606715	1.36756681611233	0.10529442947435	0.39248482163244
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0005092	GDP-dissociation inhibitor activity	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0008429	phosphatidylethanolamine binding	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0008484	sulfuric ester hydrolase activity	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0016018	cyclosporin A binding	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0016805	dipeptidase activity	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0036041	long-chain fatty acid binding	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0051787	misfolded protein binding	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0070492	oligosaccharide binding	2/621	17/18639	0.117647058823529	3.5311167945439	0.108460642960587	0.39248482163244
GO:0005154	epidermal growth factor receptor binding	3/621	35/18639	0.0857142857142857	2.57267080745342	0.110030631854466	0.39248482163244
GO:0061631	ubiquitin conjugating enzyme activity	3/621	35/18639	0.0857142857142857	2.57267080745342	0.110030631854466	0.39248482163244
GO:0098632	cell-cell adhesion mediator activity	4/621	55/18639	0.0727272727272727	2.1828722002635	0.110403801241486	0.39248482163244
GO:0030414	peptidase inhibitor activity	9/621	169/18639	0.0532544378698225	1.59840493954206	0.11245540036306	0.39248482163244
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	12/621	243/18639	0.0493827160493827	1.48219717301843	0.113862429407775	0.39248482163244
GO:0055106	ubiquitin-protein transferase regulator activity	3/621	36/18639	0.0833333333333333	2.5012077294686	0.117220956781415	0.39248482163244
GO:0015085	calcium ion transmembrane transporter activity	8/621	147/18639	0.054421768707483	1.63344178251011	0.118472694235894	0.39248482163244
GO:0004676	3-phosphoinositide-dependent protein kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0004711	ribosomal protein S6 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0035175	histone H3S10 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0035979	histone H2AXS139 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0044022	histone H3S28 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0044023	histone H4S1 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0044024	histone H2AS1 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0044025	histone H2BS14 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0072354	histone H3T3 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0072371	histone H2AS121 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0072518	Rho-dependent protein serine/threonine kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0140823	histone H2BS36 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0140855	histone H3S57 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0140995	histone H2A kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0140997	histone H4 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0140998	histone H2B kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:1990244	histone H2AT120 kinase activity	12/621	245/18639	0.0489795918367347	1.47009760425909	0.118887128853847	0.39248482163244
GO:0015172	acidic amino acid transmembrane transporter activity	2/621	18/18639	0.111111111111111	3.33494363929147	0.119433087949893	0.39248482163244
GO:0034185	apolipoprotein binding	2/621	18/18639	0.111111111111111	3.33494363929147	0.119433087949893	0.39248482163244
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/621	18/18639	0.111111111111111	3.33494363929147	0.119433087949893	0.39248482163244
GO:0070064	proline-rich region binding	2/621	18/18639	0.111111111111111	3.33494363929147	0.119433087949893	0.39248482163244
GO:0004677	DNA-dependent protein kinase activity	12/621	246/18639	0.0487804878048781	1.46412159773772	0.121446337988265	0.396229599119986
GO:0140857	histone H3T45 kinase activity	12/621	246/18639	0.0487804878048781	1.46412159773772	0.121446337988265	0.396229599119986
GO:0046332	SMAD binding	5/621	79/18639	0.0632911392405063	1.89965144010273	0.123355564884944	0.400360248271909
GO:0033218	amide binding	12/621	247/18639	0.048582995951417	1.45819397993311	0.124036637005961	0.400360248271909
GO:0035402	histone H3T11 kinase activity	12/621	247/18639	0.048582995951417	1.45819397993311	0.124036637005961	0.400360248271909
GO:0004679	AMP-activated protein kinase activity	12/621	248/18639	0.0483870967741935	1.4523141654979	0.126657901961714	0.406870301675824
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/621	58/18639	0.0689655172413793	2.06996501749125	0.127399300634988	0.406870301675824
GO:0061980	regulatory RNA binding	4/621	58/18639	0.0689655172413793	2.06996501749125	0.127399300634988	0.406870301675824
GO:0022821	solute:potassium antiporter activity	2/621	19/18639	0.105263157894737	3.15942028985507	0.130664768767423	0.412937091540254
GO:0046624	sphingolipid transporter activity	2/621	19/18639	0.105263157894737	3.15942028985507	0.130664768767423	0.412937091540254
GO:0050145	nucleoside monophosphate kinase activity	2/621	19/18639	0.105263157894737	3.15942028985507	0.130664768767423	0.412937091540254
GO:0001786	phosphatidylserine binding	4/621	59/18639	0.0677966101694915	2.03488086465242	0.133294644611802	0.419785564801752
GO:0098531	ligand-modulated transcription factor activity	4/621	60/18639	0.0666666666666667	2.00096618357488	0.139299551738777	0.434035548752932
GO:0003774	cytoskeletal motor activity	8/621	153/18639	0.0522875816993464	1.56938524201951	0.139368500587787	0.434035548752932
GO:0005319	lipid transporter activity	9/621	178/18639	0.050561797752809	1.51758671226185	0.141088953193955	0.434035548752932
GO:0000339	RNA cap binding	2/621	20/18639	0.1	3.00144927536232	0.142126304277421	0.434035548752932
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/621	20/18639	0.1	3.00144927536232	0.142126304277421	0.434035548752932
GO:0016004	phospholipase activator activity	2/621	20/18639	0.1	3.00144927536232	0.142126304277421	0.434035548752932
GO:0030742	GTP-dependent protein binding	2/621	20/18639	0.1	3.00144927536232	0.142126304277421	0.434035548752932
GO:0042288	MHC class I protein binding	2/621	20/18639	0.1	3.00144927536232	0.142126304277421	0.434035548752932
GO:0061608	nuclear import signal receptor activity	2/621	20/18639	0.1	3.00144927536232	0.142126304277421	0.434035548752932
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/621	40/18639	0.075	2.25108695652174	0.147603014290622	0.446253113205314
GO:0050997	quaternary ammonium group binding	3/621	40/18639	0.075	2.25108695652174	0.147603014290622	0.446253113205314
GO:0140662	ATP-dependent protein folding chaperone	3/621	40/18639	0.075	2.25108695652174	0.147603014290622	0.446253113205314
GO:0015179	L-amino acid transmembrane transporter activity	4/621	62/18639	0.0645161290322581	1.93641888733053	0.151624264311925	0.456887733325302
GO:0005123	death receptor binding	2/621	21/18639	0.0952380952380952	2.85852311939268	0.153789977728138	0.458840492761254
GO:0036122	BMP binding	2/621	21/18639	0.0952380952380952	2.85852311939268	0.153789977728138	0.458840492761254
GO:0072542	protein phosphatase activator activity	2/621	21/18639	0.0952380952380952	2.85852311939268	0.153789977728138	0.458840492761254
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/621	41/18639	0.0731707317073171	2.19618239660657	0.15556379041121	0.462611009517927
GO:0003779	actin binding	19/621	443/18639	0.0428893905191874	1.28730330094546	0.157603600119692	0.467145311465883
GO:0051015	actin filament binding	10/621	209/18639	0.0478468899521531	1.43610013175231	0.161137620870762	0.476064567197984
GO:0019894	kinesin binding	3/621	42/18639	0.0714285714285714	2.14389233954451	0.163654714084524	0.479955592622831
GO:0015297	antiporter activity	7/621	135/18639	0.0518518518518519	1.55630703166935	0.164662021016492	0.479955592622831
GO:0008093	cytoskeletal anchor activity	2/621	22/18639	0.0909090909090909	2.72859025032938	0.165629658755178	0.479955592622831
GO:0015377	chloride:monoatomic cation symporter activity	2/621	22/18639	0.0909090909090909	2.72859025032938	0.165629658755178	0.479955592622831
GO:0061133	endopeptidase activator activity	2/621	22/18639	0.0909090909090909	2.72859025032938	0.165629658755178	0.479955592622831
GO:0140517	protein-RNA adaptor activity	2/621	22/18639	0.0909090909090909	2.72859025032938	0.165629658755178	0.479955592622831
GO:0008375	acetylglucosaminyltransferase activity	3/621	43/18639	0.0697674418604651	2.09403437815976	0.171867869569744	0.496446362101139
GO:0046873	metal ion transmembrane transporter activity	19/621	450/18639	0.0422222222222222	1.26727858293076	0.173764259163915	0.500330739878321
GO:0008235	metalloexopeptidase activity	4/621	66/18639	0.0606060606060606	1.81906016688625	0.177433519028948	0.505021946552392
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/621	23/18639	0.0869565217391304	2.60995589161941	0.177620728721293	0.505021946552392
GO:0016493	C-C chemokine receptor activity	2/621	23/18639	0.0869565217391304	2.60995589161941	0.177620728721293	0.505021946552392
GO:0017134	fibroblast growth factor binding	2/621	23/18639	0.0869565217391304	2.60995589161941	0.177620728721293	0.505021946552392
GO:0001223	transcription coactivator binding	3/621	44/18639	0.0681818181818182	2.04644268774704	0.180195404865127	0.509150256114238
GO:0030547	signaling receptor inhibitor activity	3/621	44/18639	0.0681818181818182	2.04644268774704	0.180195404865127	0.509150256114238
GO:0042605	peptide antigen binding	3/621	45/18639	0.0666666666666667	2.00096618357488	0.188629546772482	0.526281921701857
GO:0140303	intramembrane lipid transporter activity	3/621	45/18639	0.0666666666666667	2.00096618357488	0.188629546772482	0.526281921701857
GO:0004622	lysophospholipase activity	2/621	24/18639	0.0833333333333333	2.5012077294686	0.18974000925745	0.526281921701857
GO:0015295	solute:proton symporter activity	2/621	24/18639	0.0833333333333333	2.5012077294686	0.18974000925745	0.526281921701857
GO:0019957	C-C chemokine binding	2/621	24/18639	0.0833333333333333	2.5012077294686	0.18974000925745	0.526281921701857
GO:0060229	lipase activator activity	2/621	24/18639	0.0833333333333333	2.5012077294686	0.18974000925745	0.526281921701857
GO:1990841	promoter-specific chromatin binding	4/621	68/18639	0.0588235294117647	1.76555839727195	0.190859528833257	0.527773148328549
GO:1990782	protein tyrosine kinase binding	6/621	117/18639	0.0512820512820513	1.53920475659606	0.195729807570769	0.538601204284695
GO:0020037	heme binding	7/621	142/18639	0.0492957746478873	1.47958767095326	0.195962951944817	0.538601204284695
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/621	46/18639	0.0652173913043478	1.95746691871456	0.197162614543402	0.538634010213452
GO:0030291	protein serine/threonine kinase inhibitor activity	3/621	46/18639	0.0652173913043478	1.95746691871456	0.197162614543402	0.538634010213452
GO:0051219	phosphoprotein binding	5/621	93/18639	0.0537634408602151	1.61368240610877	0.19845547201735	0.540537877236445
GO:0003707	nuclear steroid receptor activity	2/621	25/18639	0.08	2.40115942028986	0.201965693875251	0.544165709043508
GO:0005537	D-mannose binding	2/621	25/18639	0.08	2.40115942028986	0.201965693875251	0.544165709043508
GO:0019211	phosphatase activator activity	2/621	25/18639	0.08	2.40115942028986	0.201965693875251	0.544165709043508
GO:0030695	GTPase regulator activity	20/621	489/18639	0.0408997955010225	1.22758661569011	0.20260234831241	0.544165709043508
GO:0060589	nucleoside-triphosphatase regulator activity	20/621	490/18639	0.0408163265306122	1.22508133688258	0.205095993458822	0.544165709043508
GO:0005504	fatty acid binding	3/621	47/18639	0.0638297872340425	1.91581868640148	0.205787032196167	0.544165709043508
GO:0043495	protein-membrane adaptor activity	3/621	47/18639	0.0638297872340425	1.91581868640148	0.205787032196167	0.544165709043508
GO:0061749	forked DNA-dependent helicase activity	3/621	47/18639	0.0638297872340425	1.91581868640148	0.205787032196167	0.544165709043508
GO:0140359	ABC-type transporter activity	3/621	47/18639	0.0638297872340425	1.91581868640148	0.205787032196167	0.544165709043508
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/621	47/18639	0.0638297872340425	1.91581868640148	0.205787032196167	0.544165709043508
GO:0042277	peptide binding	11/621	249/18639	0.0441767068273092	1.32594144694721	0.210189461834923	0.546481103948998
GO:0001637	G protein-coupled chemoattractant receptor activity	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0004950	chemokine receptor activity	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0008157	protein phosphatase 1 binding	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0019865	immunoglobulin binding	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0034237	protein kinase A regulatory subunit binding	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0050681	nuclear androgen receptor binding	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0050750	low-density lipoprotein particle receptor binding	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0070006	metalloaminopeptidase activity	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0070412	R-SMAD binding	2/621	26/18639	0.0769230769230769	2.30880713489409	0.214277282525893	0.546481103948998
GO:0009378	four-way junction helicase activity	3/621	48/18639	0.0625	1.87590579710145	0.214495339587479	0.546481103948998
GO:0036121	double-stranded DNA helicase activity	3/621	48/18639	0.0625	1.87590579710145	0.214495339587479	0.546481103948998
GO:0043138	3'-5' DNA helicase activity	3/621	48/18639	0.0625	1.87590579710145	0.214495339587479	0.546481103948998
GO:0004896	cytokine receptor activity	5/621	96/18639	0.0520833333333333	1.56325483091787	0.216267164504867	0.54945187172525
GO:0001222	transcription corepressor binding	3/621	49/18639	0.0612244897959184	1.83762200532387	0.223280202318761	0.565684758388594
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/621	27/18639	0.0740740740740741	2.22329575952764	0.226655518985724	0.56946414326884
GO:0005104	fibroblast growth factor receptor binding	2/621	27/18639	0.0740740740740741	2.22329575952764	0.226655518985724	0.56946414326884
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/621	27/18639	0.0740740740740741	2.22329575952764	0.226655518985724	0.56946414326884
GO:0032813	tumor necrosis factor receptor superfamily binding	3/621	50/18639	0.06	1.80086956521739	0.232134420552453	0.581618561991921
GO:0048029	monosaccharide binding	4/621	74/18639	0.0540540540540541	1.62240501370936	0.232864612355014	0.581840780732776
GO:0050698	proteoglycan sulfotransferase activity	2/621	28/18639	0.0714285714285714	2.14389233954451	0.239082330953162	0.588175618009813
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/621	28/18639	0.0714285714285714	2.14389233954451	0.239082330953162	0.588175618009813
GO:0000510	H3-H4 histone complex chaperone activity	7/621	151/18639	0.0463576158940397	1.3914003263269	0.239290852310497	0.588175618009813
GO:0140584	chromatin extrusion motor activity	7/621	151/18639	0.0463576158940397	1.3914003263269	0.239290852310497	0.588175618009813
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	7/621	151/18639	0.0463576158940397	1.3914003263269	0.239290852310497	0.588175618009813
GO:0140849	ATP-dependent H2AZ histone chaperone activity	7/621	151/18639	0.0463576158940397	1.3914003263269	0.239290852310497	0.588175618009813
GO:0019003	GDP binding	4/621	75/18639	0.0533333333333333	1.6007729468599	0.240078004042036	0.58851553963818
GO:0015616	DNA translocase activity	7/621	152/18639	0.0460526315789474	1.38224637681159	0.244288694302547	0.594021034135147
GO:0046906	tetrapyrrole binding	7/621	152/18639	0.0460526315789474	1.38224637681159	0.244288694302547	0.594021034135147
GO:0140674	ATP-dependent histone chaperone activity	7/621	152/18639	0.0460526315789474	1.38224637681159	0.244288694302547	0.594021034135147
GO:0061775	cohesin loader activity	7/621	153/18639	0.0457516339869281	1.37321208676707	0.249319114549145	0.60311361285897
GO:0005080	protein kinase C binding	3/621	52/18639	0.0576923076923077	1.73160535117057	0.250022842816949	0.60311361285897
GO:0030159	signaling receptor complex adaptor activity	3/621	52/18639	0.0576923076923077	1.73160535117057	0.250022842816949	0.60311361285897
GO:0004629	phospholipase C activity	2/621	29/18639	0.0689655172413793	2.06996501749125	0.251540772746263	0.605165731779471
GO:0015171	amino acid transmembrane transporter activity	5/621	102/18639	0.0490196078431373	1.47129866439329	0.253254917618893	0.607677804974433
GO:0031490	chromatin DNA binding	6/621	128/18639	0.046875	1.40692934782609	0.254933569281647	0.608617522489771
GO:0005125	cytokine activity	10/621	234/18639	0.0427350427350427	1.28267063049672	0.25498859817653	0.608617522489771
GO:0005544	calcium-dependent phospholipid binding	3/621	53/18639	0.0566037735849057	1.69893355209188	0.259043385465363	0.613452612577244
GO:0008146	sulfotransferase activity	3/621	53/18639	0.0566037735849057	1.69893355209188	0.259043385465363	0.613452612577244
GO:0016860	intramolecular oxidoreductase activity	3/621	53/18639	0.0566037735849057	1.69893355209188	0.259043385465363	0.613452612577244
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/621	30/18639	0.0666666666666667	2.00096618357488	0.264014970494577	0.618112339631569
GO:0016769	transferase activity, transferring nitrogenous groups	2/621	30/18639	0.0666666666666667	2.00096618357488	0.264014970494577	0.618112339631569
GO:0140375	immune receptor activity	7/621	156/18639	0.0448717948717949	1.34680416202155	0.264594248303024	0.618112339631569
GO:0051287	NAD binding	3/621	54/18639	0.0555555555555556	1.66747181964573	0.268105971943332	0.618112339631569
GO:0016835	carbon-oxygen lyase activity	4/621	79/18639	0.0506329113924051	1.51972115208219	0.269403306194491	0.618112339631569
GO:0008237	metallopeptidase activity	8/621	184/18639	0.0434782608695652	1.3049779458097	0.271414972244304	0.618112339631569
GO:0005262	calcium channel activity	6/621	131/18639	0.0458015267175573	1.374709591769	0.271880155425853	0.618112339631569
GO:0140658	ATP-dependent chromatin remodeler activity	7/621	158/18639	0.0443037974683544	1.32975600807191	0.27491920924324	0.618112339631569
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	14/621	349/18639	0.0401146131805158	1.20401976662099	0.276077801359239	0.618112339631569
GO:0070325	lipoprotein particle receptor binding	2/621	31/18639	0.0645161290322581	1.93641888733053	0.2764900697231	0.618112339631569
GO:0140313	molecular sequestering activity	3/621	55/18639	0.0545454545454545	1.63715415019763	0.277204174099207	0.618112339631569
GO:0003689	DNA clamp loader activity	7/621	160/18639	0.04375	1.31313405797101	0.285346420848969	0.618112339631569
GO:0099106	ion channel regulator activity	7/621	160/18639	0.04375	1.31313405797101	0.285346420848969	0.618112339631569
GO:0170055	lipid transmembrane transporter activity	3/621	56/18639	0.0535714285714286	1.60791925465839	0.28633173208811	0.618112339631569
GO:0001094	TFIID-class transcription factor complex binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0003796	lysozyme activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0004935	adrenergic receptor activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0005337	nucleoside transmembrane transporter activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0005528	FK506 binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0008519	ammonium channel activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0015279	store-operated calcium channel activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0015643	toxic substance binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0030957	Tat protein binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0031434	mitogen-activated protein kinase kinase binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0031720	haptoglobin binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0035374	chondroitin sulfate binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0051880	G-quadruplex DNA binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0070513	death domain binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0098505	G-rich strand telomeric DNA binding	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0140940	histone H2A methyltransferase activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:1990259	histone H2AQ104 methyltransferase activity	1/621	10/18639	0.1	3.00144927536232	0.287469281341218	0.618112339631569
GO:0022884	macromolecule transmembrane transporter activity	2/621	32/18639	0.0625	1.87590579710145	0.288952185230193	0.618112339631569
GO:0031369	translation initiation factor binding	2/621	32/18639	0.0625	1.87590579710145	0.288952185230193	0.618112339631569
GO:0140142	nucleocytoplasmic carrier activity	2/621	32/18639	0.0625	1.87590579710145	0.288952185230193	0.618112339631569
GO:0046943	carboxylic acid transmembrane transporter activity	8/621	188/18639	0.0425531914893617	1.27721245760099	0.290663718815856	0.620310571684663
GO:0004601	peroxidase activity	3/621	57/18639	0.0526315789473684	1.57971014492754	0.29548255735369	0.624829465643034
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3/621	57/18639	0.0526315789473684	1.57971014492754	0.29548255735369	0.624829465643034
GO:0005342	organic acid transmembrane transporter activity	8/621	189/18639	0.0423280423280423	1.27045471973008	0.295528669147232	0.624829465643034
GO:0003712	transcription coregulator activity	19/621	495/18639	0.0383838383838384	1.15207143902796	0.29553675938353	0.624829465643034
GO:0044325	transmembrane transporter binding	6/621	136/18639	0.0441176470588235	1.32416879795396	0.300686728425353	0.625591838841677
GO:0030296	protein tyrosine kinase activator activity	2/621	33/18639	0.0606060606060606	1.81906016688625	0.301388353165137	0.625591838841677
GO:0140311	protein sequestering activity	2/621	33/18639	0.0606060606060606	1.81906016688625	0.301388353165137	0.625591838841677
GO:0140416	transcription regulator inhibitor activity	2/621	33/18639	0.0606060606060606	1.81906016688625	0.301388353165137	0.625591838841677
GO:0017116	single-stranded DNA helicase activity	3/621	58/18639	0.0517241379310345	1.55247376311844	0.304650734992892	0.625591838841677
GO:0004222	metalloendopeptidase activity	5/621	110/18639	0.0454545454545455	1.36429512516469	0.304677175250192	0.625591838841677
GO:0140713	histone chaperone activity	7/621	164/18639	0.0426829268292683	1.2811063980205	0.306469791137134	0.625591838841677
GO:0004016	adenylate cyclase activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0008271	secondary active sulfate transmembrane transporter activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0008526	phosphatidylinositol transfer activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0010854	adenylate cyclase regulator activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0015217	ADP transmembrane transporter activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0019206	nucleoside kinase activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0019215	intermediate filament binding	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0019864	IgG binding	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0047676	arachidonate-CoA ligase activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0097493	structural molecule activity conferring elasticity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0140537	transcription regulator activator activity	1/621	11/18639	0.0909090909090909	2.72859025032938	0.311221580245458	0.625591838841677
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/621	34/18639	0.0588235294117647	1.76555839727195	0.313786485214801	0.625591838841677
GO:0019825	oxygen binding	2/621	34/18639	0.0588235294117647	1.76555839727195	0.313786485214801	0.625591838841677
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/621	34/18639	0.0588235294117647	1.76555839727195	0.313786485214801	0.625591838841677
GO:0004879	nuclear receptor activity	3/621	59/18639	0.0508474576271186	1.52616064848931	0.313830525549022	0.625591838841677
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/621	59/18639	0.0508474576271186	1.52616064848931	0.313830525549022	0.625591838841677
GO:0036002	pre-mRNA binding	3/621	59/18639	0.0508474576271186	1.52616064848931	0.313830525549022	0.625591838841677
GO:0140104	molecular carrier activity	10/621	249/18639	0.0401606425702811	1.20540131540655	0.31851318666537	0.62884704693202
GO:0001217	DNA-binding transcription repressor activity	11/621	278/18639	0.039568345323741	1.18762381399228	0.323251002724619	0.62884704693202
GO:0000175	3'-5'-RNA exonuclease activity	2/621	35/18639	0.0571428571428571	1.71511387163561	0.326135324812396	0.62884704693202
GO:0016247	channel regulator activity	7/621	168/18639	0.0416666666666667	1.2506038647343	0.327888832796174	0.62884704693202
GO:0008081	phosphoric diester hydrolase activity	4/621	87/18639	0.0459770114942529	1.3799766783275	0.329581598230858	0.62884704693202
GO:0016836	hydro-lyase activity	3/621	61/18639	0.0491803278688525	1.47612259444048	0.332202871913223	0.62884704693202
GO:0000340	RNA 7-methylguanosine cap binding	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0003995	acyl-CoA dehydrogenase activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0005095	GTPase inhibitor activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0005247	voltage-gated chloride channel activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0005527	macrolide binding	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0008504	monoamine transmembrane transporter activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0008603	cAMP-dependent protein kinase regulator activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0010853	cyclase activator activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0015132	prostaglandin transmembrane transporter activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0015166	polyol transmembrane transporter activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0016273	arginine N-methyltransferase activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0016274	protein-arginine N-methyltransferase activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0017166	vinculin binding	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0031543	peptidyl-proline dioxygenase activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0035259	nuclear glucocorticoid receptor binding	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0036009	protein-glutamine N-methyltransferase activity	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0043047	single-stranded telomeric DNA binding	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0045295	gamma-catenin binding	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/621	12/18639	0.0833333333333333	2.5012077294686	0.334183325933003	0.62884704693202
GO:0004197	cysteine-type endopeptidase activity	4/621	88/18639	0.0454545454545455	1.36429512516469	0.33718118968718	0.629483625598289
GO:0004033	aldo-keto reductase (NADPH) activity	2/621	36/18639	0.0555555555555556	1.66747181964573	0.338424405284807	0.629483625598289
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/621	36/18639	0.0555555555555556	1.66747181964573	0.338424405284807	0.629483625598289
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/621	36/18639	0.0555555555555556	1.66747181964573	0.338424405284807	0.629483625598289
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/621	36/18639	0.0555555555555556	1.66747181964573	0.338424405284807	0.629483625598289
GO:0141108	transporter regulator activity	7/621	170/18639	0.0411764705882353	1.23589087809037	0.338685787532486	0.629483625598289
GO:0003727	single-stranded RNA binding	4/621	89/18639	0.0449438202247191	1.34896596645497	0.344787321235272	0.639513497669513
GO:0003713	transcription coactivator activity	10/621	256/18639	0.0390625	1.17244112318841	0.349299676302908	0.643899155601989
GO:0030280	structural constituent of skin epidermis	2/621	37/18639	0.0540540540540541	1.62240501370936	0.350644009858218	0.643899155601989
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0005172	vascular endothelial growth factor receptor binding	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0008253	5'-nucleotidase activity	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0019855	calcium channel inhibitor activity	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0032396	inhibitory MHC class I receptor activity	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0061459	L-arginine transmembrane transporter activity	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0071714	icosanoid transmembrane transporter activity	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0071837	HMG box domain binding	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0097157	pre-mRNA intronic binding	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0140666	annealing activity	1/621	13/18639	0.0769230769230769	2.30880713489409	0.356380789539359	0.643899155601989
GO:0005085	guanyl-nucleotide exchange factor activity	9/621	230/18639	0.0391304347826087	1.17448015122873	0.359382235806314	0.647826671226304
GO:0072341	modified amino acid binding	4/621	91/18639	0.043956043956044	1.31931836279662	0.360007163833871	0.647826671226304
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/621	38/18639	0.0526315789473684	1.57971014492754	0.362785133445009	0.647826671226304
GO:0140297	DNA-binding transcription factor binding	18/621	488/18639	0.0368852459016393	1.10709194583036	0.362794473406695	0.647826671226304
GO:0003714	transcription corepressor activity	8/621	204/18639	0.0392156862745098	1.17703893151463	0.370297330600485	0.647826671226304
GO:0019209	kinase activator activity	6/621	148/18639	0.0405405405405405	1.21680376028202	0.371627727839267	0.647826671226304
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/621	39/18639	0.0512820512820513	1.53920475659606	0.374839446137923	0.647826671226304
GO:0003730	mRNA 3'-UTR binding	10/621	262/18639	0.0381679389312977	1.14559132647417	0.376039926224279	0.647826671226304
GO:0004705	JUN kinase activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0005344	oxygen carrier activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0005347	ATP transmembrane transporter activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0005545	1-phosphatidylinositol binding	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0008191	metalloendopeptidase inhibitor activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0008195	phosphatidate phosphatase activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0008331	high voltage-gated calcium channel activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0015386	potassium:proton antiporter activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0015926	glucosidase activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0019763	immunoglobulin receptor activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0031404	chloride ion binding	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0034236	protein kinase A catalytic subunit binding	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0043176	amine binding	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0044548	S100 protein binding	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0061665	SUMO ligase activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0061783	peptidoglycan muralytic activity	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0071933	Arp2/3 complex binding	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0098847	sequence-specific single stranded DNA binding	1/621	14/18639	0.0714285714285714	2.14389233954451	0.377839370538825	0.647826671226304
GO:0004177	aminopeptidase activity	2/621	40/18639	0.05	1.50072463768116	0.386799258340412	0.653855951411831
GO:0004532	RNA exonuclease activity	2/621	40/18639	0.05	1.50072463768116	0.386799258340412	0.653855951411831
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	2/621	40/18639	0.05	1.50072463768116	0.386799258340412	0.653855951411831
GO:0003777	microtubule motor activity	3/621	68/18639	0.0441176470588235	1.32416879795396	0.396111908217643	0.653855951411831
GO:0004089	carbonate dehydratase activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0004467	long-chain fatty acid-CoA ligase activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0005041	low-density lipoprotein particle receptor activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0008252	nucleotidase activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0010181	FMN binding	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0015116	sulfate transmembrane transporter activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0015250	water channel activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0030553	cGMP binding	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0031005	filamin binding	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0033130	acetylcholine receptor binding	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0034483	heparan sulfate sulfotransferase activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0042809	nuclear vitamin D receptor binding	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0047372	monoacylglycerol lipase activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0048531	beta-1,3-galactosyltransferase activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0061578	K63-linked deubiquitinase activity	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0120283	protein serine/threonine kinase binding	1/621	15/18639	0.0666666666666667	2.00096618357488	0.398583625620457	0.653855951411831
GO:0001530	lipopolysaccharide binding	2/621	41/18639	0.0487804878048781	1.46412159773772	0.398657487464986	0.653855951411831
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/621	41/18639	0.0487804878048781	1.46412159773772	0.398657487464986	0.653855951411831
GO:0042287	MHC protein binding	2/621	41/18639	0.0487804878048781	1.46412159773772	0.398657487464986	0.653855951411831
GO:0008514	organic anion transmembrane transporter activity	10/621	269/18639	0.0371747211895911	1.11578039976294	0.407460545246743	0.663818230811744
GO:0016859	cis-trans isomerase activity	2/621	42/18639	0.0476190476190476	1.42926155969634	0.41040762613401	0.663818230811744
GO:0031492	nucleosomal DNA binding	2/621	42/18639	0.0476190476190476	1.42926155969634	0.41040762613401	0.663818230811744
GO:0051879	Hsp90 protein binding	2/621	42/18639	0.0476190476190476	1.42926155969634	0.41040762613401	0.663818230811744
GO:0042626	ATPase-coupled transmembrane transporter activity	4/621	98/18639	0.0408163265306122	1.22508133688258	0.413059117133233	0.663818230811744
GO:0016782	transferase activity, transferring sulphur-containing groups	3/621	70/18639	0.0428571428571429	1.28633540372671	0.41411039255074	0.663818230811744
GO:0000062	fatty-acyl-CoA binding	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0004707	MAP kinase activity	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0005024	transforming growth factor beta receptor activity	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0005159	insulin-like growth factor receptor binding	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0008142	oxysterol binding	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0015385	sodium:proton antiporter activity	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0034450	ubiquitin-ubiquitin ligase activity	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0043023	ribosomal large subunit binding	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/621	16/18639	0.0625	1.87590579710145	0.41863729660895	0.663818230811744
GO:0005245	voltage-gated calcium channel activity	2/621	43/18639	0.0465116279069767	1.39602291877317	0.422043711820071	0.666887886098963
GO:0008200	ion channel inhibitor activity	2/621	43/18639	0.0465116279069767	1.39602291877317	0.422043711820071	0.666887886098963
GO:0001046	core promoter sequence-specific DNA binding	2/621	44/18639	0.0454545454545455	1.36429512516469	0.433560297865545	0.674511319317503
GO:0016248	channel inhibitor activity	2/621	44/18639	0.0454545454545455	1.36429512516469	0.433560297865545	0.674511319317503
GO:0140597	protein carrier chaperone	7/621	188/18639	0.0372340425531915	1.11756090040086	0.436857853285245	0.674511319317503
GO:0016298	lipase activity	5/621	130/18639	0.0384615384615385	1.15440356744705	0.436871774010762	0.674511319317503
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0004550	nucleoside diphosphate kinase activity	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0015278	intracellularly gated calcium channel activity	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0019198	transmembrane receptor protein phosphatase activity	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0030548	acetylcholine receptor regulator activity	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0031489	myosin V binding	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0070403	NAD+ binding	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:1901567	fatty acid derivative binding	1/621	17/18639	0.0588235294117647	1.76555839727195	0.438023337461973	0.674511319317503
GO:0008238	exopeptidase activity	4/621	102/18639	0.0392156862745098	1.17703893151463	0.442975651200083	0.678044016235065
GO:0015079	potassium ion transmembrane transporter activity	6/621	160/18639	0.0375	1.12554347826087	0.443063853433396	0.678044016235065
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/621	45/18639	0.0444444444444444	1.33397745571659	0.444952425823362	0.678044016235065
GO:0141110	transporter inhibitor activity	2/621	45/18639	0.0444444444444444	1.33397745571659	0.444952425823362	0.678044016235065
GO:0003678	DNA helicase activity	3/621	74/18639	0.0405405405405405	1.21680376028202	0.449558166836501	0.678044016235065
GO:0005179	hormone activity	5/621	132/18639	0.0378787878787879	1.13691260430391	0.449947784557416	0.678044016235065
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	5/621	132/18639	0.0378787878787879	1.13691260430391	0.449947784557416	0.678044016235065
GO:0004180	carboxypeptidase activity	2/621	46/18639	0.0434782608695652	1.3049779458097	0.45621559906336	0.678044016235065
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/621	46/18639	0.0434782608695652	1.3049779458097	0.45621559906336	0.678044016235065
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0004970	glutamate-gated receptor activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0005372	water transmembrane transporter activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0008308	voltage-gated monoatomic anion channel activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0015280	ligand-gated sodium channel activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0030228	lipoprotein particle receptor activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0032393	MHC class I receptor activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0035615	clathrin adaptor activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0099602	neurotransmitter receptor regulator activity	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:1901611	phosphatidylglycerol binding	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:1990381	ubiquitin-specific protease binding	1/621	18/18639	0.0555555555555556	1.66747181964573	0.456763940374448	0.678044016235065
GO:0044183	protein folding chaperone	3/621	75/18639	0.04	1.20057971014493	0.458286506952937	0.67919258465084
GO:0051087	protein-folding chaperone binding	5/621	134/18639	0.0373134328358209	1.11994375946355	0.462943533634548	0.684975179456011
GO:0017022	myosin binding	3/621	76/18639	0.0394736842105263	1.18478260869565	0.466955450363601	0.68585456822371
GO:0140938	histone H3 methyltransferase activity	2/621	47/18639	0.0425531914893617	1.27721245760099	0.46734575759079	0.68585456822371
GO:0015103	inorganic anion transmembrane transporter activity	6/621	165/18639	0.0363636363636364	1.09143610013175	0.472426924811735	0.68585456822371
GO:0003756	protein disulfide isomerase activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0008301	DNA binding, bending	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0008381	mechanosensitive monoatomic ion channel activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0015245	fatty acid transmembrane transporter activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0042577	lipid phosphatase activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0120227	acyl-CoA binding	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0140036	ubiquitin-modified protein reader activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:1990380	K48-linked deubiquitinase activity	1/621	19/18639	0.0526315789473684	1.57971014492754	0.474880561019283	0.68585456822371
GO:0140693	molecular condensate scaffold activity	2/621	48/18639	0.0416666666666667	1.2506038647343	0.478339254025717	0.689751515741376
GO:0016922	nuclear receptor binding	5/621	137/18639	0.0364963503649635	1.09541944356289	0.482261362840944	0.694303263645612
GO:0035254	glutamate receptor binding	2/621	49/18639	0.0408163265306122	1.22508133688258	0.489192830694099	0.700265811204372
GO:0005326	neurotransmitter transmembrane transporter activity	1/621	20/18639	0.05	1.50072463768116	0.492393942953065	0.700265811204372
GO:0010851	cyclase regulator activity	1/621	20/18639	0.05	1.50072463768116	0.492393942953065	0.700265811204372
GO:0015095	magnesium ion transmembrane transporter activity	1/621	20/18639	0.05	1.50072463768116	0.492393942953065	0.700265811204372
GO:0015464	acetylcholine receptor activity	1/621	20/18639	0.05	1.50072463768116	0.492393942953065	0.700265811204372
GO:0016505	peptidase activator activity involved in apoptotic process	1/621	20/18639	0.05	1.50072463768116	0.492393942953065	0.700265811204372
GO:0140939	histone H4 methyltransferase activity	1/621	20/18639	0.05	1.50072463768116	0.492393942953065	0.700265811204372
GO:0033293	monocarboxylic acid binding	3/621	79/18639	0.0379746835443038	1.13979086406164	0.49257947910517	0.700265811204372
GO:0004620	phospholipase activity	4/621	109/18639	0.036697247706422	1.10144927536232	0.494113736621544	0.701347666847794
GO:0030295	protein kinase activator activity	5/621	139/18639	0.0359712230215827	1.07965801272026	0.495006852861867	0.701517524290177
GO:0048020	CCR chemokine receptor binding	2/621	50/18639	0.04	1.20057971014493	0.499903597783334	0.707109419725497
GO:0000049	tRNA binding	3/621	80/18639	0.0375	1.12554347826087	0.500985127814229	0.707109419725497
GO:0000287	magnesium ion binding	8/621	230/18639	0.0347826086956522	1.04398235664776	0.501291462936598	0.707109419725497
GO:0015101	organic cation transmembrane transporter activity	3/621	81/18639	0.037037037037037	1.11164787976382	0.509319227573098	0.708523000124817
GO:0030971	receptor tyrosine kinase binding	3/621	81/18639	0.037037037037037	1.11164787976382	0.509319227573098	0.708523000124817
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/621	21/18639	0.0476190476190476	1.42926155969634	0.509324141214312	0.708523000124817
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/621	21/18639	0.0476190476190476	1.42926155969634	0.509324141214312	0.708523000124817
GO:0009975	cyclase activity	1/621	21/18639	0.0476190476190476	1.42926155969634	0.509324141214312	0.708523000124817
GO:0010314	phosphatidylinositol-5-phosphate binding	1/621	21/18639	0.0476190476190476	1.42926155969634	0.509324141214312	0.708523000124817
GO:0015174	basic amino acid transmembrane transporter activity	1/621	21/18639	0.0476190476190476	1.42926155969634	0.509324141214312	0.708523000124817
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/621	21/18639	0.0476190476190476	1.42926155969634	0.509324141214312	0.708523000124817
GO:0140312	cargo adaptor activity	1/621	21/18639	0.0476190476190476	1.42926155969634	0.509324141214312	0.708523000124817
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/621	52/18639	0.0384615384615385	1.15440356744705	0.520886859304951	0.722281314253668
GO:0003823	antigen binding	6/621	174/18639	0.0344827586206897	1.03498250874563	0.524065441824159	0.722281314253668
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/621	22/18639	0.0454545454545455	1.36429512516469	0.525690545140937	0.722281314253668
GO:0070034	telomerase RNA binding	1/621	22/18639	0.0454545454545455	1.36429512516469	0.525690545140937	0.722281314253668
GO:0140035	ubiquitin-like protein reader activity	1/621	22/18639	0.0454545454545455	1.36429512516469	0.525690545140937	0.722281314253668
GO:0001540	amyloid-beta binding	3/621	83/18639	0.036144578313253	1.0848611838659	0.525764823760611	0.722281314253668
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/621	53/18639	0.0377358490566038	1.13262236806125	0.531155230828073	0.722281314253668
GO:0017046	peptide hormone binding	2/621	53/18639	0.0377358490566038	1.13262236806125	0.531155230828073	0.722281314253668
GO:0051018	protein kinase A binding	2/621	53/18639	0.0377358490566038	1.13262236806125	0.531155230828073	0.722281314253668
GO:0140296	general transcription initiation factor binding	2/621	53/18639	0.0377358490566038	1.13262236806125	0.531155230828073	0.722281314253668
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/621	53/18639	0.0377358490566038	1.13262236806125	0.531155230828073	0.722281314253668
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/621	53/18639	0.0377358490566038	1.13262236806125	0.531155230828073	0.722281314253668
GO:0001664	G protein-coupled receptor binding	10/621	297/18639	0.0336700336700337	1.01058898160347	0.531705251714598	0.722281314253668
GO:0004527	exonuclease activity	3/621	84/18639	0.0357142857142857	1.07194616977226	0.533872659609538	0.722281314253668
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	9/621	268/18639	0.0335820895522388	1.0079493835172	0.537929696285635	0.722281314253668
GO:0050661	NADP binding	2/621	54/18639	0.037037037037037	1.11164787976382	0.541272510015947	0.722281314253668
GO:0140463	chromatin-protein adaptor activity	2/621	54/18639	0.037037037037037	1.11164787976382	0.541272510015947	0.722281314253668
GO:0000295	adenine nucleotide transmembrane transporter activity	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0005158	insulin receptor binding	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0005212	structural constituent of eye lens	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0005283	amino acid:sodium symporter activity	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0016849	phosphorus-oxygen lyase activity	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0031681	G-protein beta-subunit binding	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0042171	lysophosphatidic acid acyltransferase activity	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0043274	phospholipase binding	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0070577	lysine-acetylated histone binding	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0071617	lysophospholipid acyltransferase activity	1/621	23/18639	0.0434782608695652	1.3049779458097	0.541511900432739	0.722281314253668
GO:0005096	GTPase activator activity	9/621	271/18639	0.033210332103321	0.996791272260549	0.551428032805417	0.727348254715101
GO:0042578	phosphoric ester hydrolase activity	12/621	363/18639	0.0330578512396694	0.992214636483411	0.552441880812993	0.727348254715101
GO:0008094	ATP-dependent activity, acting on DNA	7/621	210/18639	0.0333333333333333	1.00048309178744	0.553135547601236	0.727348254715101
GO:0008509	monoatomic anion transmembrane transporter activity	5/621	149/18639	0.0335570469798658	1.00719774341017	0.556778202610853	0.727348254715101
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0005315	phosphate transmembrane transporter activity	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0030215	semaphorin receptor binding	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0050699	WW domain binding	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0140033	acetylation-dependent protein binding	1/621	24/18639	0.0416666666666667	1.2506038647343	0.556806330483839	0.727348254715101
GO:0016853	isomerase activity	6/621	180/18639	0.0333333333333333	1.00048309178744	0.557339621859972	0.727348254715101
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/621	56/18639	0.0357142857142857	1.07194616977226	0.561048672169346	0.73113670353103
GO:0000030	mannosyltransferase activity	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0005251	delayed rectifier potassium channel activity	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0008139	nuclear localization sequence binding	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0008483	transaminase activity	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0015271	outward rectifier potassium channel activity	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0015645	fatty acid ligase activity	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0017025	TBP-class protein binding	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0120515	fatty acid-CoA ligase activity	1/621	25/18639	0.04	1.20057971014493	0.571591357009196	0.735366469230271
GO:0015108	chloride transmembrane transporter activity	4/621	121/18639	0.0330578512396694	0.992214636483411	0.576670087027108	0.74003844902559
GO:0008408	3'-5' exonuclease activity	2/621	58/18639	0.0344827586206897	1.03498250874563	0.580207582042082	0.74003844902559
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/621	122/18639	0.0327868852459016	0.98408172962699	0.583200630978679	0.74003844902559
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0004435	phosphatidylinositol phospholipase C activity	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0008066	glutamate receptor activity	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0015216	purine nucleotide transmembrane transporter activity	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0030247	polysaccharide binding	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0051139	metal cation:proton antiporter activity	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0052742	phosphatidylinositol kinase activity	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0097602	cullin family protein binding	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0120014	phospholipid transfer activity	1/621	26/18639	0.0384615384615385	1.15440356744705	0.585883919988529	0.74003844902559
GO:0005261	monoatomic cation channel activity	11/621	341/18639	0.032258064516129	0.968209443665264	0.586546303729349	0.74003844902559
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/621	91/18639	0.032967032967033	0.989488772097468	0.588341205288601	0.74003844902559
GO:0016755	aminoacyltransferase activity	16/621	496/18639	0.032258064516129	0.968209443665264	0.588822546928856	0.74003844902559
GO:0031593	polyubiquitin modification-dependent protein binding	2/621	59/18639	0.0338983050847458	1.01744043232621	0.589554145427803	0.74003844902559
GO:0004386	helicase activity	5/621	155/18639	0.032258064516129	0.968209443665264	0.591987771985372	0.74003844902559
GO:0031406	carboxylic acid binding	6/621	187/18639	0.0320855614973262	0.963031853057429	0.594734115486538	0.74003844902559
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/621	60/18639	0.0333333333333333	1.00048309178744	0.598745103329593	0.74003844902559
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	2/621	60/18639	0.0333333333333333	1.00048309178744	0.598745103329593	0.74003844902559
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/621	60/18639	0.0333333333333333	1.00048309178744	0.598745103329593	0.74003844902559
GO:0004364	glutathione transferase activity	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0008266	poly(U) RNA binding	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0008320	protein transmembrane transporter activity	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0008395	steroid hydroxylase activity	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0015252	proton channel activity	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0016405	CoA-ligase activity	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0023026	MHC class II protein complex binding	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0035255	ionotropic glutamate receptor binding	1/621	27/18639	0.037037037037037	1.11164787976382	0.599700396950175	0.74003844902559
GO:0043177	organic acid binding	6/621	189/18639	0.0317460317460317	0.952841039797561	0.60510752369906	0.745696364123706
GO:0019905	syntaxin binding	2/621	61/18639	0.0327868852459016	0.98408172962699	0.607780433208114	0.747368757804268
GO:0008527	taste receptor activity	1/621	28/18639	0.0357142857142857	1.07194616977226	0.613056621616731	0.747368757804268
GO:0019789	SUMO transferase activity	1/621	28/18639	0.0357142857142857	1.07194616977226	0.613056621616731	0.747368757804268
GO:0045499	chemorepellent activity	1/621	28/18639	0.0357142857142857	1.07194616977226	0.613056621616731	0.747368757804268
GO:0046966	nuclear thyroid hormone receptor binding	1/621	28/18639	0.0357142857142857	1.07194616977226	0.613056621616731	0.747368757804268
GO:0051537	2 iron, 2 sulfur cluster binding	1/621	28/18639	0.0357142857142857	1.07194616977226	0.613056621616731	0.747368757804268
GO:0097718	disordered domain specific binding	1/621	28/18639	0.0357142857142857	1.07194616977226	0.613056621616731	0.747368757804268
GO:0141052	histone H3 demethylase activity	1/621	28/18639	0.0357142857142857	1.07194616977226	0.613056621616731	0.747368757804268
GO:0022824	transmitter-gated monoatomic ion channel activity	2/621	63/18639	0.0317460317460317	0.952841039797561	0.625384976994091	0.755995854931711
GO:0022835	transmitter-gated channel activity	2/621	63/18639	0.0317460317460317	0.952841039797561	0.625384976994091	0.755995854931711
GO:0005416	amino acid:monoatomic cation symporter activity	1/621	29/18639	0.0344827586206897	1.03498250874563	0.625967901933533	0.755995854931711
GO:0035250	UDP-galactosyltransferase activity	1/621	29/18639	0.0344827586206897	1.03498250874563	0.625967901933533	0.755995854931711
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/621	29/18639	0.0344827586206897	1.03498250874563	0.625967901933533	0.755995854931711
GO:0051861	glycolipid binding	1/621	29/18639	0.0344827586206897	1.03498250874563	0.625967901933533	0.755995854931711
GO:0099604	ligand-gated calcium channel activity	1/621	29/18639	0.0344827586206897	1.03498250874563	0.625967901933533	0.755995854931711
GO:0035591	signaling adaptor activity	4/621	129/18639	0.0310077519379845	0.930681945848781	0.627236433553719	0.756520538873967
GO:0019787	ubiquitin-like protein transferase activity	15/621	479/18639	0.0313152400835073	0.9399110465644	0.634144651626501	0.759906259240541
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0008187	poly-pyrimidine tract binding	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0015215	nucleotide transmembrane transporter activity	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0031624	ubiquitin conjugating enzyme binding	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0032452	histone demethylase activity	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0048019	receptor antagonist activity	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0051721	protein phosphatase 2A binding	1/621	30/18639	0.0333333333333333	1.00048309178744	0.638449037500394	0.759906259240541
GO:0004725	protein tyrosine phosphatase activity	3/621	98/18639	0.0306122448979592	0.918811002661934	0.638551181574672	0.759906259240541
GO:0031072	heat shock protein binding	4/621	131/18639	0.0305343511450382	0.916473061179334	0.639259620507754	0.759906259240541
GO:0005164	tumor necrosis factor receptor binding	1/621	31/18639	0.032258064516129	0.968209443665264	0.650514336426304	0.76825065512846
GO:0005452	solute:inorganic anion antiporter activity	1/621	31/18639	0.032258064516129	0.968209443665264	0.650514336426304	0.76825065512846
GO:0016411	acylglycerol O-acyltransferase activity	1/621	31/18639	0.032258064516129	0.968209443665264	0.650514336426304	0.76825065512846
GO:0016878	acid-thiol ligase activity	1/621	31/18639	0.032258064516129	0.968209443665264	0.650514336426304	0.76825065512846
GO:0140457	protein demethylase activity	1/621	31/18639	0.032258064516129	0.968209443665264	0.650514336426304	0.76825065512846
GO:0042054	histone methyltransferase activity	2/621	67/18639	0.0298507462686567	0.895955007570842	0.658743474816133	0.77679006575657
GO:0016829	lyase activity	6/621	200/18639	0.03	0.900434782608696	0.659457938955412	0.77679006575657
GO:0008378	galactosyltransferase activity	1/621	32/18639	0.03125	0.937952898550725	0.662177631626178	0.777972942856145
GO:0042910	xenobiotic transmembrane transporter activity	1/621	32/18639	0.03125	0.937952898550725	0.662177631626178	0.777972942856145
GO:0140223	general transcription initiation factor activity	2/621	68/18639	0.0294117647058824	0.882779198635976	0.666702007137299	0.782275188193442
GO:0004722	protein serine/threonine phosphatase activity	3/621	103/18639	0.029126213592233	0.874208526804559	0.671695801988526	0.786350456794806
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/621	33/18639	0.0303030303030303	0.909530083443127	0.673452296578086	0.786350456794806
GO:0019239	deaminase activity	1/621	33/18639	0.0303030303030303	0.909530083443127	0.673452296578086	0.786350456794806
GO:0016279	protein-lysine N-methyltransferase activity	2/621	69/18639	0.0289855072463768	0.869985297206469	0.67451009414152	0.786350456794806
GO:0098960	postsynaptic neurotransmitter receptor activity	2/621	69/18639	0.0289855072463768	0.869985297206469	0.67451009414152	0.786350456794806
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/621	70/18639	0.0285714285714286	0.857556935817805	0.68216890889419	0.790709036085126
GO:0016278	lysine N-methyltransferase activity	2/621	70/18639	0.0285714285714286	0.857556935817805	0.68216890889419	0.790709036085126
GO:0008376	acetylgalactosaminyltransferase activity	1/621	34/18639	0.0294117647058824	0.882779198635976	0.684351260558792	0.790709036085126
GO:0015020	glucuronosyltransferase activity	1/621	34/18639	0.0294117647058824	0.882779198635976	0.684351260558792	0.790709036085126
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/621	34/18639	0.0294117647058824	0.882779198635976	0.684351260558792	0.790709036085126
GO:0016831	carboxy-lyase activity	1/621	34/18639	0.0294117647058824	0.882779198635976	0.684351260558792	0.790709036085126
GO:0090482	vitamin transmembrane transporter activity	1/621	34/18639	0.0294117647058824	0.882779198635976	0.684351260558792	0.790709036085126
GO:0005244	voltage-gated monoatomic ion channel activity	5/621	173/18639	0.0289017341040462	0.86747088883304	0.687594283591594	0.793445311981649
GO:0004497	monooxygenase activity	3/621	106/18639	0.0283018867924528	0.849466776045939	0.690484846111059	0.795768431286824
GO:0016791	phosphatase activity	8/621	273/18639	0.0293040293040293	0.879545575197749	0.69302347515174	0.797680573556635
GO:0005343	organic acid:sodium symporter activity	1/621	35/18639	0.0285714285714286	0.857556935817805	0.694887023374862	0.79881182534981
GO:0004721	phosphoprotein phosphatase activity	5/621	175/18639	0.0285714285714286	0.857556935817805	0.697219185053576	0.799466246325656
GO:0022832	voltage-gated channel activity	5/621	175/18639	0.0285714285714286	0.857556935817805	0.697219185053576	0.799466246325656
GO:0061659	ubiquitin-like protein ligase activity	11/621	372/18639	0.0295698924731183	0.887525323359825	0.69900619345628	0.800503304879856
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/621	73/18639	0.0273972602739726	0.822314869962279	0.704262739749171	0.802383945210349
GO:0043539	protein serine/threonine kinase activator activity	2/621	73/18639	0.0273972602739726	0.822314869962279	0.704262739749171	0.802383945210349
GO:0004190	aspartic-type endopeptidase activity	1/621	36/18639	0.0277777777777778	0.833735909822866	0.705071669606006	0.802383945210349
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/621	36/18639	0.0277777777777778	0.833735909822866	0.705071669606006	0.802383945210349
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/621	36/18639	0.0277777777777778	0.833735909822866	0.705071669606006	0.802383945210349
GO:0022843	voltage-gated monoatomic cation channel activity	4/621	143/18639	0.027972027972028	0.839566230870579	0.705959924154655	0.802388034095579
GO:0003684	damaged DNA binding	2/621	74/18639	0.027027027027027	0.811202506854681	0.711337866774523	0.806479306455615
GO:0031491	nucleosome binding	2/621	74/18639	0.027027027027027	0.811202506854681	0.711337866774523	0.806479306455615
GO:0022829	wide pore channel activity	1/621	37/18639	0.027027027027027	0.811202506854681	0.714916882376778	0.806504492930022
GO:0023023	MHC protein complex binding	1/621	37/18639	0.027027027027027	0.811202506854681	0.714916882376778	0.806504492930022
GO:0030551	cyclic nucleotide binding	1/621	37/18639	0.027027027027027	0.811202506854681	0.714916882376778	0.806504492930022
GO:0070001	aspartic-type peptidase activity	1/621	37/18639	0.027027027027027	0.811202506854681	0.714916882376778	0.806504492930022
GO:0008194	UDP-glycosyltransferase activity	4/621	145/18639	0.0275862068965517	0.827986006996502	0.716158704982617	0.806901795551843
GO:0005109	frizzled binding	1/621	38/18639	0.0263157894736842	0.789855072463768	0.724433956672231	0.81066019113588
GO:0005501	retinoid binding	1/621	38/18639	0.0263157894736842	0.789855072463768	0.724433956672231	0.81066019113588
GO:0019840	isoprenoid binding	1/621	38/18639	0.0263157894736842	0.789855072463768	0.724433956672231	0.81066019113588
GO:0042162	telomeric DNA binding	1/621	38/18639	0.0263157894736842	0.789855072463768	0.724433956672231	0.81066019113588
GO:0042887	amide transmembrane transporter activity	1/621	38/18639	0.0263157894736842	0.789855072463768	0.724433956672231	0.81066019113588
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	5/621	181/18639	0.0276243093922652	0.829129634077989	0.724857127906503	0.81066019113588
GO:0003724	RNA helicase activity	2/621	77/18639	0.025974025974026	0.779597214379823	0.731716441751487	0.81732366092192
GO:0004842	ubiquitin-protein transferase activity	13/621	449/18639	0.0289532293986637	0.869016493980181	0.736222441902648	0.821345331864332
GO:0032451	demethylase activity	1/621	40/18639	0.025	0.75036231884058	0.742527005901639	0.824710209528986
GO:0061791	GTPase motor activity	1/621	40/18639	0.025	0.75036231884058	0.742527005901639	0.824710209528986
GO:1990606	membrane scission GTPase motor activity	1/621	40/18639	0.025	0.75036231884058	0.742527005901639	0.824710209528986
GO:0061630	ubiquitin protein ligase activity	10/621	353/18639	0.028328611898017	0.850268916533235	0.742875679366242	0.824710209528986
GO:0008186	ATP-dependent activity, acting on RNA	2/621	79/18639	0.0253164556962025	0.759860576041093	0.744613146375175	0.825628513156826
GO:0008234	cysteine-type peptidase activity	5/621	187/18639	0.0267379679144385	0.802526544214524	0.75063889589211	0.827787649675987
GO:0001727	lipid kinase activity	1/621	41/18639	0.024390243902439	0.732060798868858	0.751123743862555	0.827787649675987
GO:0008227	G protein-coupled amine receptor activity	1/621	41/18639	0.024390243902439	0.732060798868858	0.751123743862555	0.827787649675987
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/621	41/18639	0.024390243902439	0.732060798868858	0.751123743862555	0.827787649675987
GO:0140318	protein transporter activity	1/621	41/18639	0.024390243902439	0.732060798868858	0.751123743862555	0.827787649675987
GO:0051117	ATPase binding	2/621	84/18639	0.0238095238095238	0.714630779848171	0.774546861435185	0.852565538011787
GO:0005267	potassium channel activity	3/621	124/18639	0.0241935483870968	0.726157082748948	0.786413448555635	0.864578179199953
GO:0016758	hexosyltransferase activity	5/621	197/18639	0.0253807106598985	0.76178915618333	0.789543591473718	0.866968568361577
GO:0140097	catalytic activity, acting on DNA	9/621	336/18639	0.0267857142857143	0.803959627329193	0.79181294002765	0.868409113186311
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	2/621	89/18639	0.0224719101123595	0.674482983227487	0.801370554543639	0.875460022346192
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	2/621	89/18639	0.0224719101123595	0.674482983227487	0.801370554543639	0.875460022346192
GO:0008188	neuropeptide receptor activity	1/621	48/18639	0.0208333333333333	0.62530193236715	0.803789002157771	0.875460022346192
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/621	48/18639	0.0208333333333333	0.62530193236715	0.803789002157771	0.875460022346192
GO:0032266	phosphatidylinositol-3-phosphate binding	1/621	48/18639	0.0208333333333333	0.62530193236715	0.803789002157771	0.875460022346192
GO:0001653	peptide receptor activity	3/621	128/18639	0.0234375	0.703464673913043	0.804033295054441	0.875460022346192
GO:0140793	histone H2AXY142 phosphatase activity	2/621	90/18639	0.0222222222222222	0.666988727858293	0.806383210114712	0.876965913158326
GO:0060590	ATPase regulator activity	1/621	49/18639	0.0204081632653061	0.61254066844129	0.810343089063265	0.880216984168121
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/621	130/18639	0.0230769230769231	0.692642140468227	0.812375728107686	0.881369360518746
GO:0015605	organophosphate ester transmembrane transporter activity	1/621	50/18639	0.02	0.600289855072464	0.816678588885304	0.884220523500347
GO:0005216	monoatomic ion channel activity	12/621	448/18639	0.0267857142857143	0.803959627329193	0.81799728909351	0.884220523500347
GO:0051213	dioxygenase activity	2/621	93/18639	0.021505376344086	0.645472962443509	0.820751920474188	0.884220523500347
GO:0005048	signal sequence binding	1/621	51/18639	0.0196078431372549	0.588519465757317	0.822802780412671	0.884220523500347
GO:0005272	sodium channel activity	1/621	51/18639	0.0196078431372549	0.588519465757317	0.822802780412671	0.884220523500347
GO:0016597	amino acid binding	1/621	51/18639	0.0196078431372549	0.588519465757317	0.822802780412671	0.884220523500347
GO:0016830	carbon-carbon lyase activity	1/621	51/18639	0.0196078431372549	0.588519465757317	0.822802780412671	0.884220523500347
GO:0030544	Hsp70 protein binding	1/621	51/18639	0.0196078431372549	0.588519465757317	0.822802780412671	0.884220523500347
GO:0008276	protein methyltransferase activity	2/621	95/18639	0.0210526315789474	0.631884057971014	0.829792685594468	0.890676882644003
GO:0022836	gated channel activity	8/621	318/18639	0.0251572327044025	0.755081578707502	0.835467741884094	0.894812051204039
GO:0099094	ligand-gated monoatomic cation channel activity	3/621	136/18639	0.0220588235294118	0.662084398976982	0.83561831022031	0.894812051204039
GO:0030594	neurotransmitter receptor activity	2/621	97/18639	0.0206185567010309	0.618855520693262	0.838420668451987	0.89525132423458
GO:0003925	G protein activity	1/621	54/18639	0.0185185185185185	0.555823939881911	0.839976711051409	0.89525132423458
GO:0017069	snRNA binding	1/621	54/18639	0.0185185185185185	0.555823939881911	0.839976711051409	0.89525132423458
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/621	54/18639	0.0185185185185185	0.555823939881911	0.839976711051409	0.89525132423458
GO:0005249	voltage-gated potassium channel activity	2/621	98/18639	0.0204081632653061	0.61254066844129	0.842584616095265	0.895925260021577
GO:0008170	N-methyltransferase activity	2/621	98/18639	0.0204081632653061	0.61254066844129	0.842584616095265	0.895925260021577
GO:0008374	O-acyltransferase activity	1/621	55/18639	0.0181818181818182	0.545718050065876	0.845323736202718	0.897785279550193
GO:0070063	RNA polymerase binding	1/621	59/18639	0.0169491525423729	0.508720216163105	0.864986399968559	0.916521804639583
GO:0070888	E-box binding	1/621	59/18639	0.0169491525423729	0.508720216163105	0.864986399968559	0.916521804639583
GO:0001098	basal transcription machinery binding	1/621	60/18639	0.0166666666666667	0.50024154589372	0.869498964318372	0.919155665077812
GO:0001099	basal RNA polymerase II transcription machinery binding	1/621	60/18639	0.0166666666666667	0.50024154589372	0.869498964318372	0.919155665077812
GO:0000149	SNARE binding	2/621	106/18639	0.0188679245283019	0.566311184030626	0.872539836730612	0.92129642830578
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/621	61/18639	0.0163934426229508	0.492040864813495	0.873860939836876	0.921618456316333
GO:0004843	cysteine-type deubiquitinase activity	2/621	108/18639	0.0185185185185185	0.555823939881911	0.879162229015808	0.926132568777396
GO:1901682	sulfur compound transmembrane transporter activity	1/621	63/18639	0.0158730158730159	0.476420519898781	0.882153027328893	0.928205099521237
GO:0005506	iron ion binding	3/621	154/18639	0.0194805194805195	0.584697910784867	0.8910227109731	0.936451447106144
GO:0001216	DNA-binding transcription activator activity	12/621	491/18639	0.0244399185336049	0.733551757726025	0.896905218107313	0.940700583080023
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/621	67/18639	0.0149253731343284	0.447977503785421	0.897140026862426	0.940700583080023
GO:0101005	deubiquitinase activity	2/621	115/18639	0.0173913043478261	0.521991178323882	0.899915978875966	0.942128622911282
GO:0030145	manganese ion binding	1/621	68/18639	0.0147058823529412	0.441389599317988	0.900579400291159	0.942128622911282
GO:0002039	p53 binding	1/621	69/18639	0.0144927536231884	0.434992648603235	0.903903948911007	0.944517144772215
GO:0140299	molecular sensor activity	1/621	71/18639	0.0140845070422535	0.422739334558073	0.910223754314694	0.950026404100607
GO:0003697	single-stranded DNA binding	2/621	121/18639	0.0165289256198347	0.496107318241706	0.915010450311715	0.952829481553072
GO:0004540	RNA nuclease activity	2/621	121/18639	0.0165289256198347	0.496107318241706	0.915010450311715	0.952829481553072
GO:0008528	G protein-coupled peptide receptor activity	2/621	122/18639	0.0163934426229508	0.492040864813495	0.917308582864531	0.953522558488629
GO:0042393	histone binding	5/621	247/18639	0.0202429149797571	0.607580824972129	0.917778603705153	0.953522558488629
GO:0004518	nuclease activity	4/621	209/18639	0.0191387559808612	0.574440052700922	0.920990133911188	0.955764360935295
GO:0051536	iron-sulfur cluster binding	1/621	76/18639	0.0131578947368421	0.394927536231884	0.924266675409189	0.958068428109868
GO:0051540	metal cluster binding	1/621	77/18639	0.012987012987013	0.389798607189912	0.926800231115211	0.959597956188923
GO:0019783	ubiquitin-like protein peptidase activity	2/621	127/18639	0.015748031496063	0.472669177222412	0.927948633676709	0.959691460370325
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	2/621	128/18639	0.015625	0.468976449275362	0.92991554381357	0.960444615321075
GO:0140030	modification-dependent protein binding	3/621	173/18639	0.0173410404624277	0.520482533299824	0.930794726424724	0.960444615321075
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	11/621	484/18639	0.0227272727272727	0.682147562582345	0.932653464191882	0.96125337317547
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/621	130/18639	0.0153846153846154	0.461761426978818	0.933698149688632	0.96125337317547
GO:0005254	chloride channel activity	1/621	83/18639	0.0120481927710843	0.361620394621966	0.940319998299423	0.965877959748105
GO:0030165	PDZ domain binding	1/621	83/18639	0.0120481927710843	0.361620394621966	0.940319998299423	0.965877959748105
GO:0140789	histone phosphatase activity	2/621	136/18639	0.0147058823529412	0.441389599317988	0.943919397058397	0.96847838589589
GO:0016757	glycosyltransferase activity	5/621	267/18639	0.0187265917602996	0.562069152689573	0.945550159015737	0.969055360708783
GO:0140767	enzyme-substrate adaptor activity	2/621	139/18639	0.0143884892086331	0.431863205088103	0.948450162809488	0.970930358541993
GO:0015276	ligand-gated monoatomic ion channel activity	3/621	186/18639	0.0161290322580645	0.484104721832632	0.949790499459717	0.971206294261514
GO:0022834	ligand-gated channel activity	3/621	188/18639	0.0159574468085106	0.47895467160037	0.952240658067182	0.972615176651952
GO:0008017	microtubule binding	5/621	276/18639	0.0181159420289855	0.543740810754043	0.955026315550953	0.974332877631952
GO:0052689	carboxylic ester hydrolase activity	1/621	92/18639	0.0108695652173913	0.326244486452426	0.956070850157042	0.974332877631952
GO:0016410	N-acyltransferase activity	1/621	94/18639	0.0106382978723404	0.319303114400247	0.95896339466646	0.976183837219393
GO:0043130	ubiquitin binding	1/621	100/18639	0.01	0.300144927536232	0.966549097451228	0.982802725771596
GO:0005253	monoatomic anion channel activity	1/621	103/18639	0.00970873786407767	0.291402842268186	0.969799433631662	0.98500345610741
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/621	167/18639	0.0119760479041916	0.359455003037403	0.976862050762733	0.989959642504803
GO:0016874	ligase activity	2/621	167/18639	0.0119760479041916	0.359455003037403	0.976862050762733	0.989959642504803
GO:0032182	ubiquitin-like protein binding	1/621	120/18639	0.00833333333333333	0.25012077294686	0.983083207357373	0.99406266787611
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	3/621	229/18639	0.0131004366812227	0.393202961837858	0.983441104172253	0.99406266787611
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/621	122/18639	0.00819672131147541	0.246020432406747	0.984198760477119	0.99406266787611
GO:0004519	endonuclease activity	1/621	127/18639	0.0078740157480315	0.236334588611206	0.986676763440545	0.994350916045083
GO:0042826	histone deacetylase binding	1/621	127/18639	0.0078740157480315	0.236334588611206	0.986676763440545	0.994350916045083
GO:0016779	nucleotidyltransferase activity	1/621	136/18639	0.00735294117647059	0.220694799658994	0.990200320284499	0.996794329076626
GO:0008168	methyltransferase activity	2/621	204/18639	0.00980392156862745	0.294259732878659	0.992232924984025	0.997733107495023
GO:0016741	transferase activity, transferring one-carbon groups	2/621	215/18639	0.00930232558139535	0.279204583754634	0.994417733804609	0.998822685006401
GO:0015631	tubulin binding	5/621	385/18639	0.012987012987013	0.389798607189912	0.996449908517011	0.999756711310762
GO:0045182	translation regulator activity	4/621	356/18639	0.0112359550561798	0.337241491613744	0.997878676169643	0.99999942114317
GO:0140098	catalytic activity, acting on RNA	4/621	387/18639	0.0103359173126615	0.310227315282927	0.999081179059453	0.99999942114317
GO:0004984	olfactory receptor activity	1/621	419/18639	0.00238663484486874	0.0716336342568572	0.99999942114317	0.99999942114317