ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 29/521 168/18639 0.172619047619048 6.17552097614478 3.3008896565001e-15 2.76944642180358e-12 GO:0001968 fibronectin binding 9/521 30/18639 0.3 10.7326295585413 8.24198816471566e-08 3.45751403509822e-05 GO:0019838 growth factor binding 17/521 136/18639 0.125 4.47192898272553 2.56282072022116e-07 7.16735528088517e-05 GO:0030695 GTPase regulator activity 34/521 489/18639 0.0695296523517382 2.48745334008455 1.12468130371658e-06 0.000183351499938399 GO:0060589 nucleoside-triphosphatase regulator activity 34/521 490/18639 0.0693877551020408 2.48237690469662 1.17752356892596e-06 0.000183351499938399 GO:0005539 glycosaminoglycan binding 22/521 242/18639 0.0909090909090909 3.25231198743675 1.31121454067985e-06 0.000183351499938399 GO:0048407 platelet-derived growth factor binding 5/521 11/18639 0.454545454545455 16.2615599371837 6.72748263604581e-06 0.000806336847377491 GO:0005178 integrin binding 16/521 161/18639 0.0993788819875776 3.55532242104887 1.19338425632102e-05 0.00125156173881667 GO:0050840 extracellular matrix binding 10/521 67/18639 0.149253731343284 5.33961669579167 1.58473923561454e-05 0.00147732913186734 GO:0030020 extracellular matrix structural constituent conferring tensile strength 8/521 44/18639 0.181818181818182 6.5046239748735 2.57970799185093e-05 0.00203846612104909 GO:0005096 GTPase activator activity 21/521 271/18639 0.0774907749077491 2.77226593763059 2.67260158897974e-05 0.00203846612104909 GO:0023023 MHC protein complex binding 7/521 37/18639 0.189189189189189 6.76832494682783 6.36500815364296e-05 0.0044502015340887 GO:0008201 heparin binding 15/521 172/18639 0.0872093023255814 3.11995045306432 0.00010101321896102 0.00651923774679197 GO:0031267 small GTPase binding 20/521 283/18639 0.0706713780918728 2.5282990715056 0.000147132028369847 0.00881741227159299 GO:0005518 collagen binding 9/521 72/18639 0.125 4.47192898272553 0.000173016242130696 0.00967737514317693 GO:0045309 protein phosphorylated amino acid binding 8/521 59/18639 0.135593220338983 4.85090601515989 0.000223632590834426 0.0102142656054861 GO:0051020 GTPase binding 21/521 315/18639 0.0666666666666667 2.38502879078695 0.000226872212474877 0.0102142656054861 GO:0004715 non-membrane spanning protein tyrosine kinase activity 7/521 45/18639 0.155555555555556 5.56506717850288 0.000231312331947837 0.0102142656054861 GO:0042605 peptide antigen binding 7/521 45/18639 0.155555555555556 5.56506717850288 0.000231312331947837 0.0102142656054861 GO:0015026 coreceptor activity 8/521 61/18639 0.131147540983607 4.69185991630219 0.000282847230642756 0.0118654413254636 GO:0001784 phosphotyrosine residue binding 7/521 47/18639 0.148936170212766 5.32825580920488 0.000305506450074917 0.0122057100768026 GO:1990782 protein tyrosine kinase binding 11/521 117/18639 0.094017094017094 3.36350214085339 0.000440187927643864 0.0167871668769637 GO:0005161 platelet-derived growth factor receptor binding 4/521 14/18639 0.285714285714286 10.2215519605155 0.000483226301781642 0.017627255095426 GO:0005080 protein kinase C binding 7/521 52/18639 0.134615384615385 4.81592351985826 0.000576288541886017 0.020146086943432 GO:0042277 peptide binding 17/521 249/18639 0.0682730923694779 2.44249936405892 0.000669984540080568 0.0224846811651039 GO:0023026 MHC class II protein complex binding 5/521 27/18639 0.185185185185185 6.62507997440819 0.000811828107046966 0.0261970685312463 GO:0051219 phosphoprotein binding 9/521 93/18639 0.0967741935483871 3.46213856727138 0.00116674912724817 0.0362556488059709 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/521 59/18639 0.11864406779661 4.24454276326491 0.00124251367423467 0.0372310347386746 GO:0002020 protease binding 11/521 136/18639 0.0808823529411765 2.89360110646946 0.00153908598139119 0.0438020910535105 GO:0004857 enzyme inhibitor activity 23/521 416/18639 0.0552884615384615 1.97796858851321 0.00156622494827809 0.0438020910535105 GO:0003779 actin binding 24/521 443/18639 0.054176072234763 1.93817238077495 0.00164025003838514 0.0439059044148307 GO:0005520 insulin-like growth factor binding 4/521 19/18639 0.210526315789474 7.53166986564299 0.00167459945324742 0.0439059044148307 GO:1901681 sulfur compound binding 17/521 275/18639 0.0618181818181818 2.21157215145699 0.00197340978897486 0.0501724488772699 GO:0038024 cargo receptor activity 7/521 65/18639 0.107692307692308 3.85273881588661 0.00219687062034235 0.0542110132490363 GO:0045296 cadherin binding 19/521 334/18639 0.0568862275449102 2.03512935740802 0.00283691397349898 0.0651864259787485 GO:0032934 sterol binding 7/521 68/18639 0.102941176470588 3.68276504459749 0.00284790262943555 0.0651864259787485 GO:0008013 beta-catenin binding 9/521 106/18639 0.0849056603773585 3.03753666751168 0.0028987325018611 0.0651864259787485 GO:0047676 arachidonate-CoA ligase activity 3/521 11/18639 0.272727272727273 9.75693596231024 0.00303011992034707 0.0651864259787485 GO:0097493 structural molecule activity conferring elasticity 3/521 11/18639 0.272727272727273 9.75693596231024 0.00303011992034707 0.0651864259787485 GO:0015485 cholesterol binding 6/521 54/18639 0.111111111111111 3.97504798464491 0.00384127046475857 0.080570647998311 GO:0043178 alcohol binding 8/521 92/18639 0.0869565217391304 3.11090711841776 0.00421685570820484 0.0862912668093625 GO:0017124 SH3 domain binding 9/521 115/18639 0.0782608695652174 2.79981640657598 0.00498528427475368 0.0918899180349798 GO:0035401 histone H3Y41 kinase activity 9/521 115/18639 0.0782608695652174 2.79981640657598 0.00498528427475368 0.0918899180349798 GO:0140801 histone H2AXY142 kinase activity 9/521 115/18639 0.0782608695652174 2.79981640657598 0.00498528427475368 0.0918899180349798 GO:0004601 peroxidase activity 6/521 57/18639 0.105263157894737 3.7658349328215 0.00503189935101033 0.0918899180349798 GO:0031994 insulin-like growth factor I binding 3/521 13/18639 0.230769230769231 8.25586889118559 0.00503806463600604 0.0918899180349798 GO:0005085 guanyl-nucleotide exchange factor activity 14/521 230/18639 0.0608695652173913 2.17763498289243 0.0054395397385946 0.0971015710783164 GO:0070851 growth factor receptor binding 10/521 139/18639 0.0719424460431655 2.57377207638879 0.0057255373552099 0.10007762168794 GO:0004713 protein tyrosine kinase activity 10/521 140/18639 0.0714285714285714 2.55538799012887 0.00601670144293872 0.103020663482155 GO:0030971 receptor tyrosine kinase binding 7/521 81/18639 0.0864197530864197 3.09170398805715 0.00750082551098092 0.1240631380067 GO:0004467 long-chain fatty acid-CoA ligase activity 3/521 15/18639 0.2 7.15508637236085 0.00768925289195281 0.1240631380067 GO:0005041 low-density lipoprotein particle receptor activity 3/521 15/18639 0.2 7.15508637236085 0.00768925289195281 0.1240631380067 GO:0008009 chemokine activity 5/521 45/18639 0.111111111111111 3.97504798464491 0.00814228744609354 0.127914962234175 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/521 29/18639 0.137931034482759 4.9345423257661 0.00823290579337956 0.127914962234175 GO:0030165 PDZ domain binding 7/521 83/18639 0.0843373493975904 3.01720509677867 0.00854220475276363 0.130307450683067 GO:0005521 lamin binding 3/521 16/18639 0.1875 6.70789347408829 0.00926975837295574 0.136444338156313 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/521 16/18639 0.1875 6.70789347408829 0.00926975837295574 0.136444338156313 GO:0016209 antioxidant activity 7/521 86/18639 0.0813953488372093 2.91195375619337 0.010298176594477 0.147722675740388 GO:0004175 endopeptidase activity 20/521 405/18639 0.0493827160493827 1.76668799317552 0.0103881261843658 0.147722675740388 GO:0005496 steroid binding 8/521 108/18639 0.0740740740740741 2.65003198976328 0.0108605265386072 0.151866362764857 GO:0141003 histone H2AX kinase activity 18/521 354/18639 0.0508474576271186 1.81908975568496 0.0110832791971298 0.152440512235933 GO:0035254 glutamate receptor binding 5/521 49/18639 0.102040816326531 3.65055427161268 0.0116069994823568 0.157068912349957 GO:0140996 histone H3 kinase activity 18/521 357/18639 0.0504201680672269 1.80380328714979 0.0120035741254576 0.159857122083475 GO:0048020 CCR chemokine receptor binding 5/521 50/18639 0.1 3.57754318618042 0.0126082889900936 0.163007578110005 GO:0030228 lipoprotein particle receptor activity 3/521 18/18639 0.166666666666667 5.96257197696737 0.0129606378059195 0.163007578110005 GO:0035173 histone kinase activity 18/521 360/18639 0.05 1.78877159309021 0.0129833887804205 0.163007578110005 GO:0005543 phospholipid binding 23/521 497/18639 0.0462776659959759 1.65560348656237 0.0130172916965081 0.163007578110005 GO:0005516 calmodulin binding 12/521 207/18639 0.0579710144927536 2.07393807894517 0.0138283797184275 0.170617802702363 GO:0051015 actin filament binding 12/521 209/18639 0.0574162679425837 2.054091781539 0.0148191998112174 0.180192878863933 GO:0042379 chemokine receptor binding 6/521 72/18639 0.0833333333333333 2.98128598848369 0.0152915453612008 0.183280093686392 GO:0140463 chromatin-protein adaptor activity 5/521 54/18639 0.0925925925925926 3.31253998720409 0.0171950034933094 0.202479403235912 GO:0016004 phospholipase activator activity 3/521 20/18639 0.15 5.36631477927063 0.0173760632097564 0.202479403235912 GO:0008236 serine-type peptidase activity 11/521 194/18639 0.0567010309278351 2.02850386845282 0.0208021353042548 0.239082075620134 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/521 22/18639 0.136363636363636 4.87846798115512 0.0225285157664779 0.252018996374332 GO:0140035 ubiquitin-like protein reader activity 3/521 22/18639 0.136363636363636 4.87846798115512 0.0225285157664779 0.252018996374332 GO:0046332 SMAD binding 6/521 79/18639 0.0759493670886076 2.71712140722564 0.023149930311527 0.25556304646541 GO:0017171 serine hydrolase activity 11/521 198/18639 0.0555555555555556 1.98752399232246 0.0237548800156453 0.257760672896068 GO:0001786 phosphatidylserine binding 5/521 59/18639 0.0847457627118644 3.03181625947493 0.0243262574816979 0.257760672896068 GO:0003823 antigen binding 10/521 174/18639 0.0574712643678161 2.05605930240254 0.02467614054378 0.257760672896068 GO:0017134 fibroblast growth factor binding 3/521 23/18639 0.130434782608696 4.66636067762664 0.0253824691393975 0.257760672896068 GO:0061134 peptidase regulator activity 12/521 226/18639 0.0530973451327434 1.89958045283916 0.0255484375705146 0.257760672896068 GO:0030246 carbohydrate binding 14/521 280/18639 0.05 1.78877159309021 0.0264145674373887 0.257760672896068 GO:0004252 serine-type endopeptidase activity 10/521 176/18639 0.0568181818181818 2.03269499214797 0.0264368463545494 0.257760672896068 GO:0050431 transforming growth factor beta binding 3/521 24/18639 0.125 4.47192898272553 0.0284212517209232 0.257760672896068 GO:0060229 lipase activator activity 3/521 24/18639 0.125 4.47192898272553 0.0284212517209232 0.257760672896068 GO:0001540 amyloid-beta binding 6/521 83/18639 0.072289156626506 2.58617579723886 0.0286757303607278 0.257760672896068 GO:0035198 miRNA binding 4/521 42/18639 0.0952380952380952 3.4071839868385 0.0292398152746292 0.257760672896068 GO:0005522 profilin binding 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0032395 MHC class II receptor activity 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0035256 G protein-coupled glutamate receptor binding 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0043208 glycosphingolipid binding 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/521 10/18639 0.2 7.15508637236085 0.0302455923622225 0.257760672896068 GO:0019888 protein phosphatase regulator activity 7/521 107/18639 0.0654205607476635 2.34044881338906 0.0305228304278009 0.257760672896068 GO:0140375 immune receptor activity 9/521 156/18639 0.0576923076923077 2.0639672227964 0.0314180659590542 0.257760672896068 GO:0019207 kinase regulator activity 14/521 287/18639 0.0487804878048781 1.74514301764899 0.0316380234399847 0.257760672896068 GO:0008483 transaminase activity 3/521 25/18639 0.12 4.29305182341651 0.031644039699994 0.257760672896068 GO:0015645 fatty acid ligase activity 3/521 25/18639 0.12 4.29305182341651 0.031644039699994 0.257760672896068 GO:0120515 fatty acid-CoA ligase activity 3/521 25/18639 0.12 4.29305182341651 0.031644039699994 0.257760672896068 GO:0061135 endopeptidase regulator activity 10/521 184/18639 0.0543478260869565 1.9443169490111 0.0343811799013078 0.274326357041651 GO:0004222 metalloendopeptidase activity 7/521 110/18639 0.0636363636363636 2.27661839120572 0.0347318497394681 0.274326357041651 GO:0004435 phosphatidylinositol phospholipase C activity 3/521 26/18639 0.115384615384615 4.1279344455928 0.03504958597356 0.274326357041651 GO:0043548 phosphatidylinositol 3-kinase binding 3/521 26/18639 0.115384615384615 4.1279344455928 0.03504958597356 0.274326357041651 GO:1901981 phosphatidylinositol phosphate binding 10/521 185/18639 0.0540540540540541 1.93380712766509 0.0354796701973808 0.274326357041651 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/521 11/18639 0.181818181818182 6.5046239748735 0.0362934751270837 0.274326357041651 GO:0140031 phosphorylation-dependent protein binding 2/521 11/18639 0.181818181818182 6.5046239748735 0.0362934751270837 0.274326357041651 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/521 11/18639 0.181818181818182 6.5046239748735 0.0362934751270837 0.274326357041651 GO:0004866 endopeptidase inhibitor activity 9/521 161/18639 0.0559006211180124 1.99986886183999 0.0373092484501 0.279486245086017 GO:0005044 scavenger receptor activity 3/521 27/18639 0.111111111111111 3.97504798464491 0.0386362533461056 0.284349268047216 GO:0016405 CoA-ligase activity 3/521 27/18639 0.111111111111111 3.97504798464491 0.0386362533461056 0.284349268047216 GO:1990841 promoter-specific chromatin binding 5/521 68/18639 0.0735294117647059 2.63054646042678 0.0414238898997533 0.289325051150759 GO:0072341 modified amino acid binding 6/521 91/18639 0.0659340659340659 2.35881968319588 0.0421727135875561 0.289325051150759 GO:0046625 sphingolipid binding 3/521 28/18639 0.107142857142857 3.83308198519331 0.0424020459634465 0.289325051150759 GO:0051019 mitogen-activated protein kinase binding 3/521 28/18639 0.107142857142857 3.83308198519331 0.0424020459634465 0.289325051150759 GO:0097718 disordered domain specific binding 3/521 28/18639 0.107142857142857 3.83308198519331 0.0424020459634465 0.289325051150759 GO:0005078 MAP-kinase scaffold activity 2/521 12/18639 0.166666666666667 5.96257197696737 0.0427607942106008 0.289325051150759 GO:0005095 GTPase inhibitor activity 2/521 12/18639 0.166666666666667 5.96257197696737 0.0427607942106008 0.289325051150759 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/521 12/18639 0.166666666666667 5.96257197696737 0.0427607942106008 0.289325051150759 GO:0045295 gamma-catenin binding 2/521 12/18639 0.166666666666667 5.96257197696737 0.0427607942106008 0.289325051150759 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/521 12/18639 0.166666666666667 5.96257197696737 0.0427607942106008 0.289325051150759 GO:0019208 phosphatase regulator activity 7/521 117/18639 0.0598290598290598 2.14041045327034 0.0460007102901762 0.301419784273906 GO:0097110 scaffold protein binding 5/521 70/18639 0.0714285714285714 2.55538799012887 0.0460035827973567 0.301419784273906 GO:0003785 actin monomer binding 3/521 29/18639 0.103448275862069 3.70090674432457 0.0463446390599927 0.301419784273906 GO:0004629 phospholipase C activity 3/521 29/18639 0.103448275862069 3.70090674432457 0.0463446390599927 0.301419784273906 GO:0043236 laminin binding 3/521 29/18639 0.103448275862069 3.70090674432457 0.0463446390599927 0.301419784273906 GO:0030414 peptidase inhibitor activity 9/521 169/18639 0.0532544378698225 1.90520051335052 0.0482308294943202 0.311274353428728 GO:0019955 cytokine binding 8/521 144/18639 0.0555555555555556 1.98752399232246 0.0494095859160495 0.31644765330966 GO:0016769 transferase activity, transferring nitrogenous groups 3/521 30/18639 0.1 3.57754318618042 0.0504614070954549 0.320735761765808 GO:0016878 acid-thiol ligase activity 3/521 31/18639 0.0967741935483871 3.46213856727138 0.0547494503538752 0.342796931693293 GO:0017147 Wnt-protein binding 3/521 31/18639 0.0967741935483871 3.46213856727138 0.0547494503538752 0.342796931693293 GO:0035091 phosphatidylinositol binding 13/521 284/18639 0.0457746478873239 1.63760779649104 0.0567790751141783 0.348109482786739 GO:0004065 arylsulfatase activity 2/521 14/18639 0.142857142857143 5.11077598025775 0.0568426688221493 0.348109482786739 GO:0042043 neurexin family protein binding 2/521 14/18639 0.142857142857143 5.11077598025775 0.0568426688221493 0.348109482786739 GO:0004864 protein phosphatase inhibitor activity 4/521 53/18639 0.0754716981132075 2.70003259334371 0.0604088085819411 0.367268046378613 GO:0005319 lipid transporter activity 9/521 178/18639 0.050561797752809 1.80887015031594 0.0628320742045572 0.375247019644259 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/521 15/18639 0.133333333333333 4.7700575815739 0.0644047328114103 0.375247019644259 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/521 15/18639 0.133333333333333 4.7700575815739 0.0644047328114103 0.375247019644259 GO:0120283 protein serine/threonine kinase binding 2/521 15/18639 0.133333333333333 4.7700575815739 0.0644047328114103 0.375247019644259 GO:0141050 histone H3K deacetylase activity 2/521 15/18639 0.133333333333333 4.7700575815739 0.0644047328114103 0.375247019644259 GO:0141051 histone H4K deacetylase activity 2/521 15/18639 0.133333333333333 4.7700575815739 0.0644047328114103 0.375247019644259 GO:0042826 histone deacetylase binding 7/521 127/18639 0.0551181102362205 1.97187419710732 0.0657703492068622 0.380560848169361 GO:0140313 molecular sequestering activity 4/521 55/18639 0.0727272727272727 2.6018495899494 0.0674245492190453 0.387460252019034 GO:0035591 signaling adaptor activity 7/521 129/18639 0.0542635658914729 1.94130250412891 0.0702551090871012 0.40097984029985 GO:0019212 phosphatase inhibitor activity 4/521 56/18639 0.0714285714285714 2.55538799012887 0.07108377990779 0.402968184747539 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/521 16/18639 0.125 4.47192898272553 0.0722811577311895 0.404292608909787 GO:0004708 MAP kinase kinase activity 2/521 16/18639 0.125 4.47192898272553 0.0722811577311895 0.404292608909787 GO:0005154 epidermal growth factor receptor binding 3/521 35/18639 0.0857142857142857 3.06646558815465 0.0735481537914855 0.405966454151687 GO:0140566 histone reader activity 3/521 35/18639 0.0857142857142857 3.06646558815465 0.0735481537914855 0.405966454151687 GO:0001618 virus receptor activity 5/521 81/18639 0.0617283950617284 2.2083599914694 0.0763707934324944 0.416643969765396 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/521 36/18639 0.0833333333333333 2.98128598848369 0.0786411638034702 0.416643969765396 GO:0061980 regulatory RNA binding 4/521 58/18639 0.0689655172413793 2.46727116288305 0.078699793314881 0.416643969765396 GO:0140272 exogenous protein binding 5/521 82/18639 0.0609756097560976 2.18142877206123 0.0795623842544349 0.416643969765396 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/521 17/18639 0.117647058823529 4.20887433668285 0.0804485376662624 0.416643969765396 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/521 17/18639 0.117647058823529 4.20887433668285 0.0804485376662624 0.416643969765396 GO:0005092 GDP-dissociation inhibitor activity 2/521 17/18639 0.117647058823529 4.20887433668285 0.0804485376662624 0.416643969765396 GO:0008484 sulfuric ester hydrolase activity 2/521 17/18639 0.117647058823529 4.20887433668285 0.0804485376662624 0.416643969765396 GO:0019198 transmembrane receptor protein phosphatase activity 2/521 17/18639 0.117647058823529 4.20887433668285 0.0804485376662624 0.416643969765396 GO:0030169 low-density lipoprotein particle binding 2/521 17/18639 0.117647058823529 4.20887433668285 0.0804485376662624 0.416643969765396 GO:0043394 proteoglycan binding 3/521 37/18639 0.0810810810810811 2.90071069149764 0.0838836058801794 0.431768989775893 GO:0033218 amide binding 11/521 247/18639 0.0445344129554656 1.59323785619371 0.087470359151415 0.447485556878276 GO:1902936 phosphatidylinositol bisphosphate binding 6/521 111/18639 0.0540540540540541 1.93380712766509 0.0911030906298228 0.462310978360945 GO:0001217 DNA-binding transcription repressor activity 12/521 278/18639 0.0431654676258993 1.54426324583328 0.0914703485195673 0.462310978360945 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/521 86/18639 0.0581395348837209 2.07996696870955 0.0930271351270736 0.467363870488711 GO:0008081 phosphoric diester hydrolase activity 5/521 87/18639 0.0574712643678161 2.05605930240254 0.0965650123893345 0.467767863980525 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/521 19/18639 0.105263157894737 3.7658349328215 0.097567790460777 0.467767863980525 GO:0030506 ankyrin binding 2/521 19/18639 0.105263157894737 3.7658349328215 0.097567790460777 0.467767863980525 GO:0043395 heparan sulfate proteoglycan binding 2/521 19/18639 0.105263157894737 3.7658349328215 0.097567790460777 0.467767863980525 GO:0050145 nucleoside monophosphate kinase activity 2/521 19/18639 0.105263157894737 3.7658349328215 0.097567790460777 0.467767863980525 GO:0097001 ceramide binding 2/521 19/18639 0.105263157894737 3.7658349328215 0.097567790460777 0.467767863980525 GO:0140036 ubiquitin-modified protein reader activity 2/521 19/18639 0.105263157894737 3.7658349328215 0.097567790460777 0.467767863980525 GO:1990380 K48-linked deubiquitinase activity 2/521 19/18639 0.105263157894737 3.7658349328215 0.097567790460777 0.467767863980525 GO:0019887 protein kinase regulator activity 11/521 255/18639 0.0431372549019608 1.54325392345038 0.103302238128964 0.49244646471705 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/521 41/18639 0.0731707317073171 2.61771452647348 0.106262366375537 0.499078364328326 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/521 41/18639 0.0731707317073171 2.61771452647348 0.106262366375537 0.499078364328326 GO:0140939 histone H4 methyltransferase activity 2/521 20/18639 0.1 3.57754318618042 0.106477982377557 0.499078364328326 GO:0019210 kinase inhibitor activity 5/521 90/18639 0.0555555555555556 1.98752399232246 0.107579805394493 0.501441426255441 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 14/521 349/18639 0.0401146131805158 1.43511761050218 0.113169645548381 0.518635209440172 GO:0001846 opsonin binding 2/521 21/18639 0.0952380952380952 3.4071839868385 0.115595690304305 0.518635209440172 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/521 21/18639 0.0952380952380952 3.4071839868385 0.115595690304305 0.518635209440172 GO:0019200 carbohydrate kinase activity 2/521 21/18639 0.0952380952380952 3.4071839868385 0.115595690304305 0.518635209440172 GO:0036122 BMP binding 2/521 21/18639 0.0952380952380952 3.4071839868385 0.115595690304305 0.518635209440172 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/521 21/18639 0.0952380952380952 3.4071839868385 0.115595690304305 0.518635209440172 GO:0072542 protein phosphatase activator activity 2/521 21/18639 0.0952380952380952 3.4071839868385 0.115595690304305 0.518635209440172 GO:0008375 acetylglucosaminyltransferase activity 3/521 43/18639 0.0697674418604651 2.49596036245146 0.118234949295216 0.527654906695141 GO:0005548 phospholipid transporter activity 4/521 68/18639 0.0588235294117647 2.10443716834143 0.12237978436234 0.542969534243709 GO:0019205 nucleobase-containing compound kinase activity 3/521 44/18639 0.0681818181818182 2.43923399057756 0.124401052690708 0.542969534243709 GO:0004407 histone deacetylase activity 2/521 22/18639 0.0909090909090909 3.25231198743675 0.124902407758088 0.542969534243709 GO:0033558 protein lysine deacetylase activity 2/521 22/18639 0.0909090909090909 3.25231198743675 0.124902407758088 0.542969534243709 GO:0140517 protein-RNA adaptor activity 2/521 22/18639 0.0909090909090909 3.25231198743675 0.124902407758088 0.542969534243709 GO:0004867 serine-type endopeptidase inhibitor activity 5/521 95/18639 0.0526315789473684 1.88291746641075 0.127226289377057 0.550220911275005 GO:0140303 intramembrane lipid transporter activity 3/521 45/18639 0.0666666666666667 2.38502879078695 0.130680831750021 0.562262655580858 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 11/521 268/18639 0.041044776119403 1.46839459134271 0.132378177455835 0.566558980447934 GO:0004602 glutathione peroxidase activity 2/521 23/18639 0.0869565217391304 3.11090711841776 0.134380497150344 0.566558980447934 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/521 23/18639 0.0869565217391304 3.11090711841776 0.134380497150344 0.566558980447934 GO:0140103 catalytic activity, acting on a glycoprotein 2/521 23/18639 0.0869565217391304 3.11090711841776 0.134380497150344 0.566558980447934 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/521 24/18639 0.0833333333333333 2.98128598848369 0.144013155825746 0.595207082452222 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/521 24/18639 0.0833333333333333 2.98128598848369 0.144013155825746 0.595207082452222 GO:0005540 hyaluronic acid binding 2/521 24/18639 0.0833333333333333 2.98128598848369 0.144013155825746 0.595207082452222 GO:0030215 semaphorin receptor binding 2/521 24/18639 0.0833333333333333 2.98128598848369 0.144013155825746 0.595207082452222 GO:0008237 metallopeptidase activity 8/521 184/18639 0.0434782608695652 1.55545355920888 0.144794859959569 0.595504350519992 GO:0005126 cytokine receptor binding 11/521 275/18639 0.04 1.43101727447217 0.149700595398301 0.608601039756026 GO:0032266 phosphatidylinositol-3-phosphate binding 3/521 48/18639 0.0625 2.23596449136276 0.150155441274729 0.608601039756026 GO:0140693 molecular condensate scaffold activity 3/521 48/18639 0.0625 2.23596449136276 0.150155441274729 0.608601039756026 GO:0019211 phosphatase activator activity 2/521 25/18639 0.08 2.86203454894434 0.153784383314942 0.617344964599217 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/521 25/18639 0.08 2.86203454894434 0.153784383314942 0.617344964599217 GO:0001222 transcription corepressor binding 3/521 49/18639 0.0612244897959184 2.19033256296761 0.156843134377642 0.626390753483779 GO:0004674 protein serine/threonine kinase activity 16/521 433/18639 0.0369515011547344 1.32195591175258 0.157530928468507 0.626390753483779 GO:0017022 myosin binding 4/521 76/18639 0.0526315789473684 1.88291746641075 0.163230317081594 0.629938710315082 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/521 26/18639 0.0769230769230769 2.75195629706186 0.163678949760057 0.629938710315082 GO:0005160 transforming growth factor beta receptor binding 2/521 26/18639 0.0769230769230769 2.75195629706186 0.163678949760057 0.629938710315082 GO:0030247 polysaccharide binding 2/521 26/18639 0.0769230769230769 2.75195629706186 0.163678949760057 0.629938710315082 GO:0034237 protein kinase A regulatory subunit binding 2/521 26/18639 0.0769230769230769 2.75195629706186 0.163678949760057 0.629938710315082 GO:0050681 nuclear androgen receptor binding 2/521 26/18639 0.0769230769230769 2.75195629706186 0.163678949760057 0.629938710315082 GO:0070412 R-SMAD binding 2/521 26/18639 0.0769230769230769 2.75195629706186 0.163678949760057 0.629938710315082 GO:0005104 fibroblast growth factor receptor binding 2/521 27/18639 0.0740740740740741 2.65003198976328 0.173682365473173 0.656394165008975 GO:0008266 poly(U) RNA binding 2/521 27/18639 0.0740740740740741 2.65003198976328 0.173682365473173 0.656394165008975 GO:0035255 ionotropic glutamate receptor binding 2/521 27/18639 0.0740740740740741 2.65003198976328 0.173682365473173 0.656394165008975 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/521 27/18639 0.0740740740740741 2.65003198976328 0.173682365473173 0.656394165008975 GO:0030159 signaling receptor complex adaptor activity 3/521 52/18639 0.0576923076923077 2.0639672227964 0.17742953873089 0.667548802669133 GO:0140789 histone phosphatase activity 6/521 136/18639 0.0441176470588235 1.57832787625607 0.181459391884508 0.675782561357706 GO:0019789 SUMO transferase activity 2/521 28/18639 0.0714285714285714 2.55538799012887 0.183780851589306 0.675782561357706 GO:0045499 chemorepellent activity 2/521 28/18639 0.0714285714285714 2.55538799012887 0.183780851589306 0.675782561357706 GO:0046875 ephrin receptor binding 2/521 28/18639 0.0714285714285714 2.55538799012887 0.183780851589306 0.675782561357706 GO:0046966 nuclear thyroid hormone receptor binding 2/521 28/18639 0.0714285714285714 2.55538799012887 0.183780851589306 0.675782561357706 GO:0051018 protein kinase A binding 3/521 53/18639 0.0566037735849057 2.02502444500779 0.184450782539827 0.675782561357706 GO:0016922 nuclear receptor binding 6/521 137/18639 0.0437956204379562 1.56680723482354 0.185649687458769 0.677217772947424 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/521 54/18639 0.0555555555555556 1.98752399232246 0.191544010160462 0.695694478461591 GO:0051861 glycolipid binding 2/521 29/18639 0.0689655172413793 2.46727116288305 0.193961311776663 0.701437674916466 GO:0001965 G-protein alpha-subunit binding 2/521 30/18639 0.0666666666666667 2.38502879078695 0.204211304968178 0.704793518291979 GO:0008187 poly-pyrimidine tract binding 2/521 30/18639 0.0666666666666667 2.38502879078695 0.204211304968178 0.704793518291979 GO:0031624 ubiquitin conjugating enzyme binding 2/521 30/18639 0.0666666666666667 2.38502879078695 0.204211304968178 0.704793518291979 GO:0048019 receptor antagonist activity 2/521 30/18639 0.0666666666666667 2.38502879078695 0.204211304968178 0.704793518291979 GO:0004860 protein kinase inhibitor activity 4/521 84/18639 0.0476190476190476 1.70359199341925 0.208221886252905 0.704793518291979 GO:0005125 cytokine activity 9/521 234/18639 0.0384615384615385 1.37597814853093 0.209655945954233 0.704793518291979 GO:0001664 G protein-coupled receptor binding 11/521 297/18639 0.037037037037037 1.32501599488164 0.211085240297758 0.704793518291979 GO:0106310 protein serine kinase activity 13/521 361/18639 0.03601108033241 1.28831195070209 0.212639439733303 0.704793518291979 GO:0016504 peptidase activator activity 3/521 57/18639 0.0526315789473684 1.88291746641075 0.21321113259279 0.704793518291979 GO:0070273 phosphatidylinositol-4-phosphate binding 2/521 31/18639 0.0645161290322581 2.30809237818092 0.214519019079509 0.704793518291979 GO:0042578 phosphoric ester hydrolase activity 13/521 363/18639 0.0358126721763085 1.28121381323266 0.218133861346726 0.704793518291979 GO:0004721 phosphoprotein phosphatase activity 7/521 175/18639 0.04 1.43101727447217 0.219103719997288 0.704793518291979 GO:0071813 lipoprotein particle binding 2/521 32/18639 0.0625 2.23596449136276 0.224873245679817 0.704793518291979 GO:0071814 protein-lipid complex binding 2/521 32/18639 0.0625 2.23596449136276 0.224873245679817 0.704793518291979 GO:0120015 sterol transfer activity 2/521 32/18639 0.0625 2.23596449136276 0.224873245679817 0.704793518291979 GO:0019956 chemokine binding 2/521 33/18639 0.0606060606060606 2.1682079916245 0.235263355582756 0.704793518291979 GO:0030296 protein tyrosine kinase activator activity 2/521 33/18639 0.0606060606060606 2.1682079916245 0.235263355582756 0.704793518291979 GO:0140311 protein sequestering activity 2/521 33/18639 0.0606060606060606 2.1682079916245 0.235263355582756 0.704793518291979 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/521 89/18639 0.0449438202247191 1.60788457805862 0.23795119438298 0.704793518291979 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/521 89/18639 0.0449438202247191 1.60788457805862 0.23795119438298 0.704793518291979 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 9/521 243/18639 0.037037037037037 1.32501599488164 0.241049872206533 0.704793518291979 GO:0140793 histone H2AXY142 phosphatase activity 4/521 90/18639 0.0444444444444444 1.59001919385797 0.244014979917329 0.704793518291979 GO:0008376 acetylgalactosaminyltransferase activity 2/521 34/18639 0.0588235294117647 2.10443716834143 0.245679275326182 0.704793518291979 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0004382 GDP phosphatase activity 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0005131 growth hormone receptor binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0005528 FK506 binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0015187 glycine transmembrane transporter activity 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0015203 polyamine transmembrane transporter activity 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0015279 store-operated calcium channel activity 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0031434 mitogen-activated protein kinase kinase binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0032356 oxidized DNA binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0043121 neurotrophin binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0050308 sugar-phosphatase activity 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0050815 phosphoserine residue binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0070097 delta-catenin binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0098505 G-rich strand telomeric DNA binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0140999 histone H3K4 trimethyltransferase activity 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:1905394 retromer complex binding 1/521 10/18639 0.1 3.57754318618042 0.246910992413375 0.704793518291979 GO:0004676 3-phosphoinositide-dependent protein kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0004711 ribosomal protein S6 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0035175 histone H3S10 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0035979 histone H2AXS139 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0044022 histone H3S28 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0044023 histone H4S1 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0044024 histone H2AS1 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0044025 histone H2BS14 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0072354 histone H3T3 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0072371 histone H2AS121 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0072518 Rho-dependent protein serine/threonine kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0140823 histone H2BS36 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0140855 histone H3S57 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0140995 histone H2A kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0140997 histone H4 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0140998 histone H2B kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:1990244 histone H2AT120 kinase activity 9/521 245/18639 0.036734693877551 1.31419953778056 0.248243161510059 0.704793518291979 GO:0004677 DNA-dependent protein kinase activity 9/521 246/18639 0.0365853658536585 1.30885726323674 0.251866951039641 0.704793518291979 GO:0140857 histone H3T45 kinase activity 9/521 246/18639 0.0365853658536585 1.30885726323674 0.251866951039641 0.704793518291979 GO:0035402 histone H3T11 kinase activity 9/521 247/18639 0.0364372469635627 1.30355824597667 0.255508283630616 0.704793518291979 GO:0035403 histone H3T6 kinase activity 9/521 247/18639 0.0364372469635627 1.30355824597667 0.255508283630616 0.704793518291979 GO:0005507 copper ion binding 3/521 63/18639 0.0476190476190476 1.70359199341925 0.257903611165892 0.704793518291979 GO:0004679 AMP-activated protein kinase activity 9/521 248/18639 0.0362903225806452 1.29830196272677 0.2591667406461 0.704793518291979 GO:0000993 RNA polymerase II complex binding 2/521 36/18639 0.0555555555555556 1.98752399232246 0.266550893963433 0.704793518291979 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/521 36/18639 0.0555555555555556 1.98752399232246 0.266550893963433 0.704793518291979 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0002162 dystroglycan binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0003953 NAD+ nucleosidase activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0005114 type II transforming growth factor beta receptor binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0005536 D-glucose binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0008432 JUN kinase binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0010854 adenylate cyclase regulator activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0015173 aromatic amino acid transmembrane transporter activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0019203 carbohydrate phosphatase activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0019206 nucleoside kinase activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0031731 CCR6 chemokine receptor binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0032794 GTPase activating protein binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0042608 T cell receptor binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0043522 leucine zipper domain binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0048185 activin binding 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:1990948 ubiquitin ligase inhibitor activity 1/521 11/18639 0.0909090909090909 3.25231198743675 0.267972744142004 0.704793518291979 GO:0120013 lipid transfer activity 3/521 65/18639 0.0461538461538462 1.65117377823712 0.273084064161528 0.712685001916504 GO:0019213 deacetylase activity 2/521 37/18639 0.0540540540540541 1.93380712766509 0.276989024711048 0.712685001916504 GO:0022829 wide pore channel activity 2/521 37/18639 0.0540540540540541 1.93380712766509 0.276989024711048 0.712685001916504 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 16/521 484/18639 0.0330578512396694 1.18265890452245 0.281034681279662 0.712685001916504 GO:0004896 cytokine receptor activity 4/521 96/18639 0.0416666666666667 1.49064299424184 0.281042827151291 0.712685001916504 GO:0016500 protein-hormone receptor activity 3/521 67/18639 0.0447761194029851 1.6018850087375 0.288354996561697 0.712685001916504 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/521 67/18639 0.0447761194029851 1.6018850087375 0.288354996561697 0.712685001916504 GO:0042054 histone methyltransferase activity 3/521 67/18639 0.0447761194029851 1.6018850087375 0.288354996561697 0.712685001916504 GO:0004859 phospholipase inhibitor activity 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0005049 nuclear export signal receptor activity 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0005527 macrolide binding 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0008504 monoamine transmembrane transporter activity 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0010853 cyclase activator activity 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0035259 nuclear glucocorticoid receptor binding 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0035497 cAMP response element binding 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0043047 single-stranded telomeric DNA binding 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0070008 serine-type exopeptidase activity 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0070679 inositol 1,4,5 trisphosphate binding 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0097371 MDM2/MDM4 family protein binding 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/521 12/18639 0.0833333333333333 2.98128598848369 0.288446557772131 0.712685001916504 GO:0140297 DNA-binding transcription factor binding 16/521 488/18639 0.0327868852459016 1.17296497907555 0.291933690656099 0.712685001916504 GO:0004725 protein tyrosine phosphatase activity 4/521 98/18639 0.0408163265306122 1.46022170864507 0.293581053154967 0.712685001916504 GO:0030145 manganese ion binding 3/521 68/18639 0.0441176470588235 1.57832787625607 0.296015390970899 0.712685001916504 GO:0000217 DNA secondary structure binding 2/521 39/18639 0.0512820512820513 1.83463753137458 0.2978295643534 0.712685001916504 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/521 39/18639 0.0512820512820513 1.83463753137458 0.2978295643534 0.712685001916504 GO:0001216 DNA-binding transcription activator activity 16/521 491/18639 0.0325865580448065 1.1657981869427 0.300194952235488 0.712685001916504 GO:0008083 growth factor activity 6/521 162/18639 0.037037037037037 1.32501599488164 0.300355659839629 0.712685001916504 GO:0016279 protein-lysine N-methyltransferase activity 3/521 69/18639 0.0434782608695652 1.55545355920888 0.303687772656186 0.712685001916504 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/521 40/18639 0.05 1.78877159309021 0.308217167640825 0.712685001916504 GO:0061791 GTPase motor activity 2/521 40/18639 0.05 1.78877159309021 0.308217167640825 0.712685001916504 GO:0071949 FAD binding 2/521 40/18639 0.05 1.78877159309021 0.308217167640825 0.712685001916504 GO:1990606 membrane scission GTPase motor activity 2/521 40/18639 0.05 1.78877159309021 0.308217167640825 0.712685001916504 GO:0004535 poly(A)-specific ribonuclease activity 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0005542 folic acid binding 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0019855 calcium channel inhibitor activity 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0030955 potassium ion binding 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0031432 titin binding 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0045159 myosin II binding 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0046975 histone H3K36 methyltransferase activity 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0070123 transforming growth factor beta receptor activity, type III 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0140333 glycerophospholipid flippase activity 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0140852 histone ubiquitin ligase activity 1/521 13/18639 0.0769230769230769 2.75195629706186 0.308348814893553 0.712685001916504 GO:0016278 lysine N-methyltransferase activity 3/521 70/18639 0.0428571428571429 1.53323279407732 0.311368775202913 0.717687918668254 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/521 41/18639 0.0487804878048781 1.74514301764899 0.318573824115968 0.71779156962905 GO:0042169 SH2 domain binding 2/521 41/18639 0.0487804878048781 1.74514301764899 0.318573824115968 0.71779156962905 GO:0042287 MHC protein binding 2/521 41/18639 0.0487804878048781 1.74514301764899 0.318573824115968 0.71779156962905 GO:0003924 GTPase activity 11/521 331/18639 0.0332326283987915 1.18891163286963 0.322129130025889 0.71779156962905 GO:0005344 oxygen carrier activity 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0008191 metalloendopeptidase inhibitor activity 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0015926 glucosidase activity 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0031404 chloride ion binding 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0032036 myosin heavy chain binding 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0034236 protein kinase A catalytic subunit binding 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0044548 S100 protein binding 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0061665 SUMO ligase activity 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0070742 C2H2 zinc finger domain binding 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0071933 Arp2/3 complex binding 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0098847 sequence-specific single stranded DNA binding 1/521 14/18639 0.0714285714285714 2.55538799012887 0.32769544151443 0.71779156962905 GO:0042056 chemoattractant activity 2/521 42/18639 0.0476190476190476 1.70359199341925 0.328893156421832 0.71779156962905 GO:0043175 RNA polymerase core enzyme binding 2/521 42/18639 0.0476190476190476 1.70359199341925 0.328893156421832 0.71779156962905 GO:0019001 guanyl nucleotide binding 13/521 400/18639 0.0325 1.16270153550864 0.328897997946295 0.71779156962905 GO:0032561 guanyl ribonucleotide binding 13/521 400/18639 0.0325 1.16270153550864 0.328897997946295 0.71779156962905 GO:0044325 transmembrane transporter binding 5/521 136/18639 0.0367647058823529 1.31527323021339 0.331717219424335 0.71779156962905 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/521 43/18639 0.0465116279069767 1.66397357496764 0.33916916652557 0.71779156962905 GO:0000774 adenyl-nucleotide exchange factor activity 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0004129 cytochrome-c oxidase activity 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0016846 carbon-sulfur lyase activity 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0030553 cGMP binding 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0042809 nuclear vitamin D receptor binding 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0047372 monoacylglycerol lipase activity 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0050700 CARD domain binding 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/521 15/18639 0.0666666666666667 2.38502879078695 0.346501920707502 0.71779156962905 GO:0030295 protein kinase activator activity 5/521 139/18639 0.0359712230215827 1.2868860381944 0.348336962634962 0.71779156962905 GO:0001046 core promoter sequence-specific DNA binding 2/521 44/18639 0.0454545454545455 1.62615599371837 0.349396219565325 0.71779156962905 GO:0001223 transcription coactivator binding 2/521 44/18639 0.0454545454545455 1.62615599371837 0.349396219565325 0.71779156962905 GO:0030547 signaling receptor inhibitor activity 2/521 44/18639 0.0454545454545455 1.62615599371837 0.349396219565325 0.71779156962905 GO:0043014 alpha-tubulin binding 2/521 44/18639 0.0454545454545455 1.62615599371837 0.349396219565325 0.71779156962905 GO:0003725 double-stranded RNA binding 3/521 75/18639 0.04 1.43101727447217 0.349791344469707 0.71779156962905 GO:0051536 iron-sulfur cluster binding 3/521 76/18639 0.0394736842105263 1.41218809980806 0.357458236006206 0.71779156962905 GO:0004620 phospholipase activity 4/521 109/18639 0.036697247706422 1.31285988483685 0.36339510172138 0.71779156962905 GO:0005024 transforming growth factor beta receptor activity 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0005159 insulin-like growth factor receptor binding 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0008142 oxysterol binding 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0016722 oxidoreductase activity, acting on metal ions 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0022841 potassium ion leak channel activity 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0022858 alanine transmembrane transporter activity 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0030275 LRR domain binding 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0055102 lipase inhibitor activity 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0140327 flippase activity 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0140328 floppase activity 1/521 16/18639 0.0625 2.23596449136276 0.364783304905924 0.71779156962905 GO:0020037 heme binding 5/521 142/18639 0.0352112676056338 1.25969830499311 0.365002281749464 0.71779156962905 GO:0051540 metal cluster binding 3/521 77/18639 0.038961038961039 1.39384799461575 0.36511261415089 0.71779156962905 GO:0005525 GTP binding 12/521 378/18639 0.0317460317460317 1.13572799561283 0.367746811482872 0.71779156962905 GO:0004180 carboxypeptidase activity 2/521 46/18639 0.0434782608695652 1.55545355920888 0.369682638147345 0.71779156962905 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/521 46/18639 0.0434782608695652 1.55545355920888 0.369682638147345 0.71779156962905 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/521 46/18639 0.0434782608695652 1.55545355920888 0.369682638147345 0.71779156962905 GO:0030276 clathrin binding 2/521 46/18639 0.0434782608695652 1.55545355920888 0.369682638147345 0.71779156962905 GO:0019199 transmembrane receptor protein kinase activity 3/521 78/18639 0.0384615384615385 1.37597814853093 0.372751806150091 0.71779156962905 GO:0005504 fatty acid binding 2/521 47/18639 0.0425531914893617 1.52235880262997 0.379732412770719 0.71779156962905 GO:0043495 protein-membrane adaptor activity 2/521 47/18639 0.0425531914893617 1.52235880262997 0.379732412770719 0.71779156962905 GO:0140938 histone H3 methyltransferase activity 2/521 47/18639 0.0425531914893617 1.52235880262997 0.379732412770719 0.71779156962905 GO:0033293 monocarboxylic acid binding 3/521 79/18639 0.0379746835443038 1.35856070361282 0.380373224727841 0.71779156962905 GO:0008194 UDP-glycosyltransferase activity 5/521 145/18639 0.0344827586206897 1.23363558144152 0.381681724010465 0.71779156962905 GO:0005200 structural constituent of cytoskeleton 4/521 112/18639 0.0357142857142857 1.27769399506444 0.382481749851601 0.71779156962905 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0008429 phosphatidylethanolamine binding 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0008569 minus-end-directed microtubule motor activity 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0016805 dipeptidase activity 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0017110 nucleoside diphosphate phosphatase activity 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0031489 myosin V binding 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0032977 membrane insertase activity 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0036041 long-chain fatty acid binding 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0038191 neuropilin binding 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0045125 bioactive lipid receptor activity 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0046965 nuclear retinoid X receptor binding 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0070492 oligosaccharide binding 1/521 17/18639 0.0588235294117647 2.10443716834143 0.382554227858403 0.71779156962905 GO:0048306 calcium-dependent protein binding 3/521 80/18639 0.0375 1.34157869481766 0.387974367448117 0.71779156962905 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/521 48/18639 0.0416666666666667 1.49064299424184 0.389714020227067 0.71779156962905 GO:0015101 organic cation transmembrane transporter activity 3/521 81/18639 0.037037037037037 1.32501599488164 0.395552815989444 0.71779156962905 GO:0019209 kinase activator activity 5/521 148/18639 0.0337837837837838 1.20862945479068 0.398345069300732 0.71779156962905 GO:0005004 GPI-linked ephrin receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0005008 hepatocyte growth factor receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0005009 insulin receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0005011 macrophage colony-stimulating factor receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0005020 stem cell factor receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0008288 boss receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0036332 placental growth factor receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0038062 protein tyrosine kinase collagen receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0060175 brain-derived neurotrophic factor receptor activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0060590 ATPase regulator activity 2/521 49/18639 0.0408163265306122 1.46022170864507 0.399623419624915 0.71779156962905 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0004970 glutamate-gated receptor activity 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0017128 phospholipid scramblase activity 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0035615 clathrin adaptor activity 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0070064 proline-rich region binding 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0070628 proteasome binding 1/521 18/18639 0.0555555555555556 1.98752399232246 0.399828916253085 0.71779156962905 GO:0001221 transcription coregulator binding 4/521 115/18639 0.0347826086956522 1.2443628473671 0.40150278666527 0.71779156962905 GO:0005006 epidermal growth factor receptor activity 2/521 50/18639 0.04 1.43101727447217 0.409456848293338 0.71779156962905 GO:0005007 fibroblast growth factor receptor activity 2/521 50/18639 0.04 1.43101727447217 0.409456848293338 0.71779156962905 GO:0005017 platelet-derived growth factor receptor activity 2/521 50/18639 0.04 1.43101727447217 0.409456848293338 0.71779156962905 GO:0005019 platelet-derived growth factor beta-receptor activity 2/521 50/18639 0.04 1.43101727447217 0.409456848293338 0.71779156962905 GO:0003712 transcription coregulator activity 15/521 495/18639 0.0303030303030303 1.08410399581225 0.411679967990538 0.71779156962905 GO:0003756 protein disulfide isomerase activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0005229 intracellularly calcium-gated chloride channel activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0015245 fatty acid transmembrane transporter activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0022840 leak channel activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0022842 narrow pore channel activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0031420 alkali metal ion binding 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0042800 histone H3K4 methyltransferase activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0042834 peptidoglycan binding 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0141147 intracellularly calcium-gated channel activity 1/521 19/18639 0.0526315789473684 1.88291746641075 0.416621201019324 0.71779156962905 GO:0051117 ATPase binding 3/521 84/18639 0.0357142857142857 1.27769399506444 0.418129057602398 0.71779156962905 GO:0003743 translation initiation factor activity 2/521 51/18639 0.0392156862745098 1.40295811222762 0.419210809437705 0.71779156962905 GO:0005010 insulin-like growth factor receptor activity 2/521 51/18639 0.0392156862745098 1.40295811222762 0.419210809437705 0.71779156962905 GO:0005021 vascular endothelial growth factor receptor activity 2/521 51/18639 0.0392156862745098 1.40295811222762 0.419210809437705 0.71779156962905 GO:0005030 neurotrophin receptor activity 2/521 51/18639 0.0392156862745098 1.40295811222762 0.419210809437705 0.71779156962905 GO:0016597 amino acid binding 2/521 51/18639 0.0392156862745098 1.40295811222762 0.419210809437705 0.71779156962905 GO:0046906 tetrapyrrole binding 5/521 152/18639 0.0328947368421053 1.17682341650672 0.420488063503031 0.718512189977684 GO:0031406 carboxylic acid binding 6/521 187/18639 0.0320855614973262 1.14787481909532 0.424544068894103 0.723968442687301 GO:0005326 neurotransmitter transmembrane transporter activity 1/521 20/18639 0.05 1.78877159309021 0.432944528316259 0.731360470929147 GO:0010851 cyclase regulator activity 1/521 20/18639 0.05 1.78877159309021 0.432944528316259 0.731360470929147 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/521 20/18639 0.05 1.78877159309021 0.432944528316259 0.731360470929147 GO:0042288 MHC class I protein binding 1/521 20/18639 0.05 1.78877159309021 0.432944528316259 0.731360470929147 GO:0043177 organic acid binding 6/521 189/18639 0.0317460317460317 1.13572799561283 0.43448112192028 0.731360470929147 GO:0005003 ephrin receptor activity 2/521 53/18639 0.0377358490566038 1.35001629667186 0.438467600568964 0.731360470929147 GO:0005005 transmembrane-ephrin receptor activity 2/521 53/18639 0.0377358490566038 1.35001629667186 0.438467600568964 0.731360470929147 GO:0005246 calcium channel regulator activity 2/521 53/18639 0.0377358490566038 1.35001629667186 0.438467600568964 0.731360470929147 GO:0005544 calcium-dependent phospholipid binding 2/521 53/18639 0.0377358490566038 1.35001629667186 0.438467600568964 0.731360470929147 GO:0016860 intramolecular oxidoreductase activity 2/521 53/18639 0.0377358490566038 1.35001629667186 0.438467600568964 0.731360470929147 GO:0038064 collagen receptor activity 2/521 53/18639 0.0377358490566038 1.35001629667186 0.438467600568964 0.731360470929147 GO:0004197 cysteine-type endopeptidase activity 3/521 88/18639 0.0340909090909091 1.21961699528878 0.447780639156434 0.734894719330971 GO:0003925 G protein activity 2/521 54/18639 0.037037037037037 1.32501599488164 0.447964661738521 0.734894719330971 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/521 21/18639 0.0476190476190476 1.70359199341925 0.448811970216857 0.734894719330971 GO:0008373 sialyltransferase activity 1/521 21/18639 0.0476190476190476 1.70359199341925 0.448811970216857 0.734894719330971 GO:0009975 cyclase activity 1/521 21/18639 0.0476190476190476 1.70359199341925 0.448811970216857 0.734894719330971 GO:0010314 phosphatidylinositol-5-phosphate binding 1/521 21/18639 0.0476190476190476 1.70359199341925 0.448811970216857 0.734894719330971 GO:0140312 cargo adaptor activity 1/521 21/18639 0.0476190476190476 1.70359199341925 0.448811970216857 0.734894719330971 GO:0003727 single-stranded RNA binding 3/521 89/18639 0.0337078651685393 1.20591343354396 0.455100270950857 0.734894719330971 GO:0005243 gap junction channel activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0008093 cytoskeletal anchor activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0032931 histone H3K56 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0043992 histone H3K9 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0043993 histone H3K18 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0043994 histone H3K23 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0043999 histone H2AK5 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0044012 histone H2AK9 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0044014 histone H2BK5 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0044015 histone H2BK12 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0044016 histone H3K4 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0044017 histone H3K27 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0044018 histone H3K36 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0046972 histone H4K16 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0050321 tau-protein kinase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0061133 endopeptidase activator activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0070034 telomerase RNA binding 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0140908 histone H3K122 acetyltransferase activity 1/521 22/18639 0.0454545454545455 1.62615599371837 0.464236235095846 0.734894719330971 GO:0031625 ubiquitin protein ligase binding 9/521 302/18639 0.0298013245033113 1.06615525415973 0.470176472574054 0.740467218444283 GO:0016757 glycosyltransferase activity 8/521 267/18639 0.0299625468164794 1.07192305203908 0.47139629500322 0.740467218444283 GO:0016758 hexosyltransferase activity 6/521 197/18639 0.0304568527918782 1.08960706178084 0.473876933487077 0.740467218444283 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/521 57/18639 0.0350877192982456 1.2552783109405 0.475900539472675 0.740467218444283 GO:0004519 endonuclease activity 4/521 127/18639 0.031496062992126 1.1267852554899 0.476156123579922 0.740467218444283 GO:0003887 DNA-directed DNA polymerase activity 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0005158 insulin receptor binding 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0005283 amino acid:sodium symporter activity 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0016849 phosphorus-oxygen lyase activity 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0031681 G-protein beta-subunit binding 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0043274 phospholipase binding 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0044013 histone H2B acetyltransferase activity 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0099186 structural constituent of postsynapse 1/521 23/18639 0.0434782608695652 1.55545355920888 0.479229677729733 0.740467218444283 GO:0031490 chromatin DNA binding 4/521 128/18639 0.03125 1.11798224568138 0.482229814971807 0.743733115370121 GO:0004622 lysophospholipase activity 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0015149 hexose transmembrane transporter activity 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0015295 solute:proton symporter activity 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0030552 cAMP binding 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0035035 histone acetyltransferase binding 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0043998 histone H2A acetyltransferase activity 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0055056 D-glucose transmembrane transporter activity 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0070300 phosphatidic acid binding 1/521 24/18639 0.0416666666666667 1.49064299424184 0.493804309116863 0.744544547117365 GO:0004879 nuclear receptor activity 2/521 59/18639 0.0338983050847458 1.21272650378997 0.494040794608926 0.744544547117365 GO:0031593 polyubiquitin modification-dependent protein binding 2/521 59/18639 0.0338983050847458 1.21272650378997 0.494040794608926 0.744544547117365 GO:0070063 RNA polymerase binding 2/521 59/18639 0.0338983050847458 1.21272650378997 0.494040794608926 0.744544547117365 GO:0016298 lipase activity 4/521 130/18639 0.0307692307692308 1.10078251882475 0.49429238706123 0.744544547117365 GO:0016791 phosphatase activity 8/521 273/18639 0.0293040293040293 1.04836430364261 0.496402800591569 0.746383422394851 GO:0008276 protein methyltransferase activity 3/521 95/18639 0.0315789473684211 1.12975047984645 0.498106041139715 0.746389396243794 GO:0005262 calcium channel activity 4/521 131/18639 0.0305343511450382 1.09237959883372 0.500279300211717 0.746389396243794 GO:0001098 basal transcription machinery binding 2/521 60/18639 0.0333333333333333 1.19251439539347 0.502960529534793 0.746389396243794 GO:0001099 basal RNA polymerase II transcription machinery binding 2/521 60/18639 0.0333333333333333 1.19251439539347 0.502960529534793 0.746389396243794 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/521 60/18639 0.0333333333333333 1.19251439539347 0.502960529534793 0.746389396243794 GO:0098531 ligand-modulated transcription factor activity 2/521 60/18639 0.0333333333333333 1.19251439539347 0.502960529534793 0.746389396243794 GO:0005179 hormone activity 4/521 132/18639 0.0303030303030303 1.08410399581225 0.506235374374852 0.746389396243794 GO:0000030 mannosyltransferase activity 1/521 25/18639 0.04 1.43101727447217 0.507971806025276 0.746389396243794 GO:0001848 complement binding 1/521 25/18639 0.04 1.43101727447217 0.507971806025276 0.746389396243794 GO:0015271 outward rectifier potassium channel activity 1/521 25/18639 0.04 1.43101727447217 0.507971806025276 0.746389396243794 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/521 25/18639 0.04 1.43101727447217 0.507971806025276 0.746389396243794 GO:0042974 nuclear retinoic acid receptor binding 1/521 25/18639 0.04 1.43101727447217 0.507971806025276 0.746389396243794 GO:0120020 cholesterol transfer activity 1/521 25/18639 0.04 1.43101727447217 0.507971806025276 0.746389396243794 GO:0051087 protein-folding chaperone binding 4/521 134/18639 0.0298507462686567 1.06792333915834 0.518051428784972 0.754728988812875 GO:0008170 N-methyltransferase activity 3/521 98/18639 0.0306122448979592 1.0951662814838 0.518958648968435 0.754728988812875 GO:0015179 L-amino acid transmembrane transporter activity 2/521 62/18639 0.032258064516129 1.15404618909046 0.520492099966183 0.754728988812875 GO:0008066 glutamate receptor activity 1/521 26/18639 0.0384615384615385 1.37597814853093 0.521743520275885 0.754728988812875 GO:0008143 poly(A) binding 1/521 26/18639 0.0384615384615385 1.37597814853093 0.521743520275885 0.754728988812875 GO:0008157 protein phosphatase 1 binding 1/521 26/18639 0.0384615384615385 1.37597814853093 0.521743520275885 0.754728988812875 GO:0015145 monosaccharide transmembrane transporter activity 1/521 26/18639 0.0384615384615385 1.37597814853093 0.521743520275885 0.754728988812875 GO:0030507 spectrin binding 1/521 26/18639 0.0384615384615385 1.37597814853093 0.521743520275885 0.754728988812875 GO:0052742 phosphatidylinositol kinase activity 1/521 26/18639 0.0384615384615385 1.37597814853093 0.521743520275885 0.754728988812875 GO:0043130 ubiquitin binding 3/521 100/18639 0.03 1.07326295585413 0.532597144267968 0.766168053306486 GO:0001671 ATPase activator activity 1/521 27/18639 0.037037037037037 1.32501599488164 0.535130487768297 0.766168053306486 GO:0004364 glutathione transferase activity 1/521 27/18639 0.037037037037037 1.32501599488164 0.535130487768297 0.766168053306486 GO:0008395 steroid hydroxylase activity 1/521 27/18639 0.037037037037037 1.32501599488164 0.535130487768297 0.766168053306486 GO:0015252 proton channel activity 1/521 27/18639 0.037037037037037 1.32501599488164 0.535130487768297 0.766168053306486 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/521 27/18639 0.037037037037037 1.32501599488164 0.535130487768297 0.766168053306486 GO:0003735 structural constituent of ribosome 5/521 175/18639 0.0285714285714286 1.02215519605155 0.543296533059483 0.771631449426385 GO:0160215 deacylase activity 2/521 65/18639 0.0307692307692308 1.10078251882475 0.546002962303034 0.771631449426385 GO:0015171 amino acid transmembrane transporter activity 3/521 102/18639 0.0294117647058824 1.05221858417071 0.546015544147446 0.771631449426385 GO:0140104 molecular carrier activity 7/521 249/18639 0.0281124497991968 1.00573503225956 0.547320475058229 0.771631449426385 GO:0044389 ubiquitin-like protein ligase binding 9/521 322/18639 0.0279503105590062 0.999934430919994 0.547431112267144 0.771631449426385 GO:0036408 histone H3K14 acetyltransferase activity 1/521 28/18639 0.0357142857142857 1.27769399506444 0.548143437256407 0.771631449426385 GO:0051119 sugar transmembrane transporter activity 1/521 28/18639 0.0357142857142857 1.27769399506444 0.548143437256407 0.771631449426385 GO:0051537 2 iron, 2 sulfur cluster binding 1/521 28/18639 0.0357142857142857 1.27769399506444 0.548143437256407 0.771631449426385 GO:0051959 dynein light intermediate chain binding 1/521 28/18639 0.0357142857142857 1.27769399506444 0.548143437256407 0.771631449426385 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/521 28/18639 0.0357142857142857 1.27769399506444 0.548143437256407 0.771631449426385 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/521 29/18639 0.0344827586206897 1.23363558144152 0.560792798880684 0.782870479635431 GO:0005416 amino acid:monoatomic cation symporter activity 1/521 29/18639 0.0344827586206897 1.23363558144152 0.560792798880684 0.782870479635431 GO:0010484 histone H3 acetyltransferase activity 1/521 29/18639 0.0344827586206897 1.23363558144152 0.560792798880684 0.782870479635431 GO:0097472 cyclin-dependent protein kinase activity 1/521 29/18639 0.0344827586206897 1.23363558144152 0.560792798880684 0.782870479635431 GO:0099604 ligand-gated calcium channel activity 1/521 29/18639 0.0344827586206897 1.23363558144152 0.560792798880684 0.782870479635431 GO:0003777 microtubule motor activity 2/521 68/18639 0.0294117647058824 1.05221858417071 0.570550651621126 0.788231852060967 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/521 68/18639 0.0294117647058824 1.05221858417071 0.570550651621126 0.788231852060967 GO:0004497 monooxygenase activity 3/521 106/18639 0.0283018867924528 1.01251222250389 0.572164580353828 0.788231852060967 GO:0043995 histone H4K5 acetyltransferase activity 1/521 30/18639 0.0333333333333333 1.19251439539347 0.573088712463873 0.788231852060967 GO:0043996 histone H4K8 acetyltransferase activity 1/521 30/18639 0.0333333333333333 1.19251439539347 0.573088712463873 0.788231852060967 GO:0043997 histone H4K12 acetyltransferase activity 1/521 30/18639 0.0333333333333333 1.19251439539347 0.573088712463873 0.788231852060967 GO:0051721 protein phosphatase 2A binding 1/521 30/18639 0.0333333333333333 1.19251439539347 0.573088712463873 0.788231852060967 GO:0070566 adenylyltransferase activity 1/521 30/18639 0.0333333333333333 1.19251439539347 0.573088712463873 0.788231852060967 GO:0098918 structural constituent of synapse 1/521 30/18639 0.0333333333333333 1.19251439539347 0.573088712463873 0.788231852060967 GO:0003713 transcription coactivator activity 7/521 256/18639 0.02734375 0.978234464971209 0.576768809521302 0.791995141061166 GO:0002039 p53 binding 2/521 69/18639 0.0289855072463768 1.03696903947259 0.578516707709632 0.793097251255525 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/521 31/18639 0.032258064516129 1.15404618909046 0.585041035576686 0.800733162885546 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/521 70/18639 0.0285714285714286 1.02215519605155 0.586373999842183 0.801250465582396 GO:0015085 calcium ion transmembrane transporter activity 4/521 147/18639 0.0272108843537415 0.973481139096713 0.591336343799096 0.806717386093401 GO:0022884 macromolecule transmembrane transporter activity 1/521 32/18639 0.03125 1.11798224568138 0.59665935137981 0.80741483194784 GO:0031369 translation initiation factor binding 1/521 32/18639 0.03125 1.11798224568138 0.59665935137981 0.80741483194784 GO:0051059 NF-kappaB binding 1/521 32/18639 0.03125 1.11798224568138 0.59665935137981 0.80741483194784 GO:0070717 poly-purine tract binding 1/521 32/18639 0.03125 1.11798224568138 0.59665935137981 0.80741483194784 GO:0140142 nucleocytoplasmic carrier activity 1/521 32/18639 0.03125 1.11798224568138 0.59665935137981 0.80741483194784 GO:0046943 carboxylic acid transmembrane transporter activity 5/521 188/18639 0.0265957446808511 0.951474251643729 0.607059115155296 0.807700590604355 GO:0140597 protein carrier chaperone 5/521 188/18639 0.0265957446808511 0.951474251643729 0.607059115155296 0.807700590604355 GO:0042923 neuropeptide binding 1/521 33/18639 0.0303030303030303 1.08410399581225 0.607952976248469 0.807700590604355 GO:0071889 14-3-3 protein binding 1/521 33/18639 0.0303030303030303 1.08410399581225 0.607952976248469 0.807700590604355 GO:0140416 transcription regulator inhibitor activity 1/521 33/18639 0.0303030303030303 1.08410399581225 0.607952976248469 0.807700590604355 GO:0004521 RNA endonuclease activity 2/521 73/18639 0.0273972602739726 0.980148818131622 0.609292206551125 0.807700590604355 GO:0043539 protein serine/threonine kinase activator activity 2/521 73/18639 0.0273972602739726 0.980148818131622 0.609292206551125 0.807700590604355 GO:0005342 organic acid transmembrane transporter activity 5/521 189/18639 0.0264550264550265 0.946439996344027 0.611748734536683 0.807700590604355 GO:0000510 H3-H4 histone complex chaperone activity 4/521 151/18639 0.0264900662251656 0.947693559253092 0.612525756736998 0.807700590604355 GO:0140584 chromatin extrusion motor activity 4/521 151/18639 0.0264900662251656 0.947693559253092 0.612525756736998 0.807700590604355 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/521 151/18639 0.0264900662251656 0.947693559253092 0.612525756736998 0.807700590604355 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/521 151/18639 0.0264900662251656 0.947693559253092 0.612525756736998 0.807700590604355 GO:0019902 phosphatase binding 5/521 190/18639 0.0263157894736842 0.941458733205374 0.616405758435698 0.807700590604355 GO:0031491 nucleosome binding 2/521 74/18639 0.027027027027027 0.966903563832547 0.616713804002112 0.807700590604355 GO:0048029 monosaccharide binding 2/521 74/18639 0.027027027027027 0.966903563832547 0.616713804002112 0.807700590604355 GO:0015616 DNA translocase activity 4/521 152/18639 0.0263157894736842 0.941458733205374 0.617715964662241 0.807700590604355 GO:0140674 ATP-dependent histone chaperone activity 4/521 152/18639 0.0263157894736842 0.941458733205374 0.617715964662241 0.807700590604355 GO:0015020 glucuronosyltransferase activity 1/521 34/18639 0.0294117647058824 1.05221858417071 0.618930967185508 0.807700590604355 GO:0015035 protein-disulfide reductase activity 1/521 34/18639 0.0294117647058824 1.05221858417071 0.618930967185508 0.807700590604355 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/521 34/18639 0.0294117647058824 1.05221858417071 0.618930967185508 0.807700590604355 GO:0019825 oxygen binding 1/521 34/18639 0.0294117647058824 1.05221858417071 0.618930967185508 0.807700590604355 GO:0051427 hormone receptor binding 1/521 34/18639 0.0294117647058824 1.05221858417071 0.618930967185508 0.807700590604355 GO:0016887 ATP hydrolysis activity 11/521 417/18639 0.026378896882494 0.943716428009224 0.620379164270655 0.807700590604355 GO:0003774 cytoskeletal motor activity 4/521 153/18639 0.0261437908496732 0.935305408151744 0.622862603724525 0.807700590604355 GO:0061775 cohesin loader activity 4/521 153/18639 0.0261437908496732 0.935305408151744 0.622862603724525 0.807700590604355 GO:0019003 GDP binding 2/521 75/18639 0.0266666666666667 0.954011516314779 0.62402674809889 0.807700590604355 GO:0005506 iron ion binding 4/521 154/18639 0.025974025974026 0.929231996410499 0.627965360213566 0.807700590604355 GO:0008514 organic anion transmembrane transporter activity 7/521 269/18639 0.0260223048327138 0.93095919342985 0.628890304863142 0.807700590604355 GO:0000175 3'-5'-RNA exonuclease activity 1/521 35/18639 0.0285714285714286 1.02215519605155 0.629602129028902 0.807700590604355 GO:0005343 organic acid:sodium symporter activity 1/521 35/18639 0.0285714285714286 1.02215519605155 0.629602129028902 0.807700590604355 GO:0010485 histone H4 acetyltransferase activity 1/521 35/18639 0.0285714285714286 1.02215519605155 0.629602129028902 0.807700590604355 GO:0034061 DNA polymerase activity 1/521 35/18639 0.0285714285714286 1.02215519605155 0.629602129028902 0.807700590604355 GO:0043015 gamma-tubulin binding 1/521 35/18639 0.0285714285714286 1.02215519605155 0.629602129028902 0.807700590604355 GO:0061631 ubiquitin conjugating enzyme activity 1/521 35/18639 0.0285714285714286 1.02215519605155 0.629602129028902 0.807700590604355 GO:0004386 helicase activity 4/521 155/18639 0.0258064516129032 0.923236951272367 0.633023943458488 0.810850516888048 GO:0015631 tubulin binding 10/521 385/18639 0.025974025974026 0.929231996410499 0.637970286786857 0.814778517457344 GO:0003724 RNA helicase activity 2/521 77/18639 0.025974025974026 0.929231996410499 0.63832780083521 0.814778517457344 GO:0045505 dynein intermediate chain binding 1/521 36/18639 0.0277777777777778 0.993761996161228 0.639975021459344 0.814778517457344 GO:0055106 ubiquitin-protein transferase regulator activity 1/521 36/18639 0.0277777777777778 0.993761996161228 0.639975021459344 0.814778517457344 GO:0140658 ATP-dependent chromatin remodeler activity 4/521 158/18639 0.0253164556962025 0.905707135741879 0.647932082532599 0.819279429890347 GO:0030551 cyclic nucleotide binding 1/521 37/18639 0.027027027027027 0.966903563832547 0.650057965813463 0.819279429890347 GO:0008186 ATP-dependent activity, acting on RNA 2/521 79/18639 0.0253164556962025 0.905707135741879 0.652198290023277 0.819279429890347 GO:0008017 microtubule binding 7/521 276/18639 0.0253623188405797 0.907347909538513 0.655412900174643 0.819279429890347 GO:0032182 ubiquitin-like protein binding 3/521 120/18639 0.025 0.894385796545106 0.655978810900512 0.819279429890347 GO:0003689 DNA clamp loader activity 4/521 160/18639 0.025 0.894385796545106 0.657645639836829 0.819279429890347 GO:0099106 ion channel regulator activity 4/521 160/18639 0.025 0.894385796545106 0.657645639836829 0.819279429890347 GO:0000049 tRNA binding 2/521 80/18639 0.025 0.894385796545106 0.658973262397 0.819279429890347 GO:0005109 frizzled binding 1/521 38/18639 0.0263157894736842 0.941458733205374 0.659859051708054 0.819279429890347 GO:0005501 retinoid binding 1/521 38/18639 0.0263157894736842 0.941458733205374 0.659859051708054 0.819279429890347 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/521 38/18639 0.0263157894736842 0.941458733205374 0.659859051708054 0.819279429890347 GO:0019840 isoprenoid binding 1/521 38/18639 0.0263157894736842 0.941458733205374 0.659859051708054 0.819279429890347 GO:0042162 telomeric DNA binding 1/521 38/18639 0.0263157894736842 0.941458733205374 0.659859051708054 0.819279429890347 GO:0004540 RNA nuclease activity 3/521 121/18639 0.0247933884297521 0.88699417839184 0.661490453650186 0.819279429890347 GO:0033192 calmodulin-dependent protein phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:0140791 histone H2AXS140 phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/521 81/18639 0.0246913580246914 0.883343996587759 0.66564213445795 0.819279429890347 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/521 39/18639 0.0256410256410256 0.917318765687288 0.669386143480545 0.819279429890347 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/521 82/18639 0.024390243902439 0.872571508824493 0.672205531935929 0.819279429890347 GO:0033549 MAP kinase phosphatase activity 2/521 82/18639 0.024390243902439 0.872571508824493 0.672205531935929 0.819279429890347 GO:0140713 histone chaperone activity 4/521 164/18639 0.024390243902439 0.872571508824493 0.676526223367167 0.819279429890347 GO:0005267 potassium channel activity 3/521 124/18639 0.0241935483870968 0.865534641817844 0.677640589742797 0.819279429890347 GO:0003714 transcription corepressor activity 5/521 204/18639 0.0245098039215686 0.87684882014226 0.678036532578545 0.819279429890347 GO:0004532 RNA exonuclease activity 1/521 40/18639 0.025 0.894385796545106 0.678646886450795 0.819279429890347 GO:0015036 disulfide oxidoreductase activity 1/521 40/18639 0.025 0.894385796545106 0.678646886450795 0.819279429890347 GO:0015144 carbohydrate transmembrane transporter activity 1/521 40/18639 0.025 0.894385796545106 0.678646886450795 0.819279429890347 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/521 40/18639 0.025 0.894385796545106 0.678646886450795 0.819279429890347 GO:0030331 nuclear estrogen receptor binding 1/521 40/18639 0.025 0.894385796545106 0.678646886450795 0.819279429890347 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/521 83/18639 0.0240963855421687 0.86205859907962 0.678664128455055 0.819279429890347 GO:0005254 chloride channel activity 2/521 83/18639 0.0240963855421687 0.86205859907962 0.678664128455055 0.819279429890347 GO:0008135 translation factor activity, RNA binding 2/521 83/18639 0.0240963855421687 0.86205859907962 0.678664128455055 0.819279429890347 GO:0017018 myosin phosphatase activity 2/521 84/18639 0.0238095238095238 0.851795996709624 0.68501864237829 0.821847963268789 GO:0180051 translation factor activity 2/521 84/18639 0.0238095238095238 0.851795996709624 0.68501864237829 0.821847963268789 GO:0001530 lipopolysaccharide binding 1/521 41/18639 0.024390243902439 0.872571508824493 0.687648713009165 0.821847963268789 GO:0001727 lipid kinase activity 1/521 41/18639 0.024390243902439 0.872571508824493 0.687648713009165 0.821847963268789 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/521 41/18639 0.024390243902439 0.872571508824493 0.687648713009165 0.821847963268789 GO:0017080 sodium channel regulator activity 1/521 41/18639 0.024390243902439 0.872571508824493 0.687648713009165 0.821847963268789 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/521 41/18639 0.024390243902439 0.872571508824493 0.687648713009165 0.821847963268789 GO:0016874 ligase activity 4/521 167/18639 0.0239520958083832 0.856896571540221 0.690204981491234 0.823729700527944 GO:0016247 channel regulator activity 4/521 168/18639 0.0238095238095238 0.851795996709624 0.69467247375842 0.825252307798645 GO:0015291 secondary active transmembrane transporter activity 7/521 287/18639 0.024390243902439 0.872571508824493 0.694723517587175 0.825252307798645 GO:0004402 histone acetyltransferase activity 1/521 42/18639 0.0238095238095238 0.851795996709624 0.696398848535686 0.825252307798645 GO:0019894 kinesin binding 1/521 42/18639 0.0238095238095238 0.851795996709624 0.696398848535686 0.825252307798645 GO:0031492 nucleosomal DNA binding 1/521 42/18639 0.0238095238095238 0.851795996709624 0.696398848535686 0.825252307798645 GO:0050660 flavin adenine dinucleotide binding 2/521 86/18639 0.0232558139534884 0.831986787483819 0.697418501613838 0.82526256486608 GO:0004518 nuclease activity 5/521 209/18639 0.0239234449760766 0.855871575641249 0.698374756918852 0.82526256486608 GO:0141108 transporter regulator activity 4/521 170/18639 0.0235294117647059 0.84177486733657 0.703469184127067 0.828311935704514 GO:0005245 voltage-gated calcium channel activity 1/521 43/18639 0.0232558139534884 0.831986787483819 0.704904317154974 0.828311935704514 GO:0008200 ion channel inhibitor activity 1/521 43/18639 0.0232558139534884 0.831986787483819 0.704904317154974 0.828311935704514 GO:0048156 tau protein binding 1/521 43/18639 0.0232558139534884 0.831986787483819 0.704904317154974 0.828311935704514 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/521 130/18639 0.0230769230769231 0.825586889118559 0.708214733590902 0.831037988087786 GO:0003954 NADH dehydrogenase activity 1/521 44/18639 0.0227272727272727 0.813077996859187 0.713171947331478 0.834520591089414 GO:0016248 channel inhibitor activity 1/521 44/18639 0.0227272727272727 0.813077996859187 0.713171947331478 0.834520591089414 GO:0061659 ubiquitin-like protein ligase activity 9/521 372/18639 0.0241935483870968 0.865534641817844 0.716202083740256 0.8358712705274 GO:0140030 modification-dependent protein binding 4/521 173/18639 0.023121387283237 0.827177615301832 0.716318764611681 0.8358712705274 GO:0051539 4 iron, 4 sulfur cluster binding 1/521 45/18639 0.0222222222222222 0.795009596928983 0.721208377309445 0.839242480669381 GO:0141110 transporter inhibitor activity 1/521 45/18639 0.0222222222222222 0.795009596928983 0.721208377309445 0.839242480669381 GO:0030291 protein serine/threonine kinase inhibitor activity 1/521 46/18639 0.0217391304347826 0.77772677960444 0.729020060401936 0.847157660217762 GO:0015297 antiporter activity 3/521 135/18639 0.0222222222222222 0.795009596928983 0.731955193945936 0.848926557200039 GO:0016755 aminoacyltransferase activity 12/521 496/18639 0.0241935483870968 0.865534641817844 0.735223948143084 0.848926557200039 GO:0061733 protein-lysine-acetyltransferase activity 1/521 47/18639 0.0212765957446809 0.761179401314984 0.736613270133049 0.848926557200039 GO:0061749 forked DNA-dependent helicase activity 1/521 47/18639 0.0212765957446809 0.761179401314984 0.736613270133049 0.848926557200039 GO:0099095 ligand-gated monoatomic anion channel activity 1/521 47/18639 0.0212765957446809 0.761179401314984 0.736613270133049 0.848926557200039 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/521 47/18639 0.0212765957446809 0.761179401314984 0.736613270133049 0.848926557200039 GO:0051213 dioxygenase activity 2/521 93/18639 0.021505376344086 0.769364126060306 0.737662563524486 0.848969671875231 GO:0005261 monoatomic cation channel activity 8/521 341/18639 0.0234604105571848 0.839306319338515 0.740698630109793 0.850423779692378 GO:0016410 N-acyltransferase activity 2/521 94/18639 0.0212765957446809 0.761179401314984 0.743023609755557 0.850423779692378 GO:0009378 four-way junction helicase activity 1/521 48/18639 0.0208333333333333 0.745321497120921 0.743994105237432 0.850423779692378 GO:0036121 double-stranded DNA helicase activity 1/521 48/18639 0.0208333333333333 0.745321497120921 0.743994105237432 0.850423779692378 GO:0043138 3'-5' DNA helicase activity 1/521 48/18639 0.0208333333333333 0.745321497120921 0.743994105237432 0.850423779692378 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/521 181/18639 0.0220994475138122 0.790617278713906 0.748569587954642 0.854489638495162 GO:0016763 pentosyltransferase activity 1/521 49/18639 0.0204081632653061 0.730110854322535 0.751168494521026 0.856291259379267 GO:0015605 organophosphate ester transmembrane transporter activity 1/521 50/18639 0.02 0.715508637236084 0.758142201586897 0.863068259337051 GO:0005249 voltage-gated potassium channel activity 2/521 98/18639 0.0204081632653061 0.730110854322535 0.763538394232533 0.866940447835959 GO:0015078 proton transmembrane transporter activity 4/521 185/18639 0.0216216216216216 0.773522851066037 0.763610239512246 0.866940447835959 GO:0005048 signal sequence binding 1/521 51/18639 0.0196078431372549 0.701479056113808 0.764920829429881 0.867254832286041 GO:0022843 voltage-gated monoatomic cation channel activity 3/521 143/18639 0.020979020979021 0.750533535562326 0.766743690618294 0.868148389242576 GO:0019903 protein phosphatase binding 3/521 144/18639 0.0208333333333333 0.745321497120921 0.770823220550289 0.870065901133136 GO:0061630 ubiquitin protein ligase activity 8/521 353/18639 0.0226628895184136 0.810774659757603 0.773931884906723 0.870065901133136 GO:0000287 magnesium ion binding 5/521 230/18639 0.0217391304347826 0.77772677960444 0.77395139116435 0.870065901133136 GO:0008146 sulfotransferase activity 1/521 53/18639 0.0188679245283019 0.675008148335929 0.777914483063966 0.870065901133136 GO:0017046 peptide hormone binding 1/521 53/18639 0.0188679245283019 0.675008148335929 0.777914483063966 0.870065901133136 GO:0034212 protein N-acetyltransferase activity 1/521 53/18639 0.0188679245283019 0.675008148335929 0.777914483063966 0.870065901133136 GO:0140296 general transcription initiation factor binding 1/521 53/18639 0.0188679245283019 0.675008148335929 0.777914483063966 0.870065901133136 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/521 53/18639 0.0188679245283019 0.675008148335929 0.777914483063966 0.870065901133136 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/521 53/18639 0.0188679245283019 0.675008148335929 0.777914483063966 0.870065901133136 GO:0015293 symporter activity 3/521 146/18639 0.0205479452054795 0.735111613598717 0.778807499107253 0.870065901133136 GO:0008238 exopeptidase activity 2/521 102/18639 0.0196078431372549 0.701479056113808 0.78261813823471 0.873160396248566 GO:0051287 NAD binding 1/521 54/18639 0.0185185185185185 0.662507997440819 0.784139951390861 0.873696439863124 GO:0004722 protein serine/threonine phosphatase activity 2/521 103/18639 0.0194174757281553 0.694668579840859 0.787172161619852 0.873863054965163 GO:0005253 monoatomic anion channel activity 2/521 103/18639 0.0194174757281553 0.694668579840859 0.787172161619852 0.873863054965163 GO:0019787 ubiquitin-like protein transferase activity 11/521 479/18639 0.022964509394572 0.821565241085274 0.787414147263007 0.873863054965163 GO:0019842 vitamin binding 3/521 150/18639 0.02 0.715508637236084 0.794089738046139 0.878822908806728 GO:0030170 pyridoxal phosphate binding 1/521 56/18639 0.0178571428571429 0.638846997532218 0.796073195105022 0.878822908806728 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/521 56/18639 0.0178571428571429 0.638846997532218 0.796073195105022 0.878822908806728 GO:0170055 lipid transmembrane transporter activity 1/521 56/18639 0.0178571428571429 0.638846997532218 0.796073195105022 0.878822908806728 GO:0070279 vitamin B6 binding 1/521 57/18639 0.0175438596491228 0.62763915547025 0.801790563955599 0.883971462757881 GO:0005216 monoatomic ion channel activity 10/521 448/18639 0.0223214285714286 0.798558746915273 0.807320500564773 0.885444339355054 GO:0008408 3'-5' exonuclease activity 1/521 58/18639 0.0172413793103448 0.616817790720762 0.807347937552582 0.885444339355054 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/521 58/18639 0.0172413793103448 0.616817790720762 0.807347937552582 0.885444339355054 GO:0017116 single-stranded DNA helicase activity 1/521 58/18639 0.0172413793103448 0.616817790720762 0.807347937552582 0.885444339355054 GO:0004843 cysteine-type deubiquitinase activity 2/521 108/18639 0.0185185185185185 0.662507997440819 0.808703271546964 0.885600206103299 GO:0015459 potassium channel regulator activity 1/521 59/18639 0.0169491525423729 0.606363251894987 0.812749784844714 0.885600206103299 GO:0036002 pre-mRNA binding 1/521 59/18639 0.0169491525423729 0.606363251894987 0.812749784844714 0.885600206103299 GO:0070888 E-box binding 1/521 59/18639 0.0169491525423729 0.606363251894987 0.812749784844714 0.885600206103299 GO:0046982 protein heterodimerization activity 8/521 369/18639 0.021680216802168 0.775619118955105 0.813289865066674 0.885600206103299 GO:0016829 lyase activity 4/521 200/18639 0.02 0.715508637236084 0.813823312164057 0.885600206103299 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/521 60/18639 0.0166666666666667 0.596257197696737 0.81800045018895 0.888992717239027 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/521 61/18639 0.0163934426229508 0.586482489537774 0.823104156817485 0.892227890917145 GO:0016836 hydro-lyase activity 1/521 61/18639 0.0163934426229508 0.586482489537774 0.823104156817485 0.892227890917145 GO:0022804 active transmembrane transporter activity 10/521 457/18639 0.0218818380743982 0.782832207041668 0.825807259690293 0.894002955974394 GO:0015079 potassium ion transmembrane transporter activity 3/521 160/18639 0.01875 0.670789347408829 0.828475413565332 0.895735659769734 GO:0022824 transmitter-gated monoatomic ion channel activity 1/521 63/18639 0.0158730158730159 0.567863997806416 0.832887001363218 0.89819048090455 GO:0022835 transmitter-gated channel activity 1/521 63/18639 0.0158730158730159 0.567863997806416 0.832887001363218 0.89819048090455 GO:0101005 deubiquitinase activity 2/521 115/18639 0.0173913043478261 0.622181423683552 0.835584240372754 0.899942461710835 GO:0009055 electron transfer activity 2/521 116/18639 0.0172413793103448 0.616817790720762 0.839133225734493 0.90145041791452 GO:0015294 solute:monoatomic cation symporter activity 2/521 116/18639 0.0172413793103448 0.616817790720762 0.839133225734493 0.90145041791452 GO:0008094 ATP-dependent activity, acting on DNA 4/521 210/18639 0.019047619047619 0.6814367973677 0.842191604380549 0.903578971963274 GO:0022853 active monoatomic ion transmembrane transporter activity 2/521 118/18639 0.0169491525423729 0.606363251894987 0.846023965189894 0.905946700011515 GO:0008235 metalloexopeptidase activity 1/521 66/18639 0.0151515151515152 0.542051997906125 0.846558060559031 0.905946700011515 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/521 167/18639 0.0179640718562874 0.642672428655166 0.849516790679379 0.907954888382164 GO:0003697 single-stranded DNA binding 2/521 121/18639 0.0165289256198347 0.591329452261227 0.855858386630378 0.912399434863404 GO:0015108 chloride transmembrane transporter activity 2/521 121/18639 0.0165289256198347 0.591329452261227 0.855858386630378 0.912399434863404 GO:0008528 G protein-coupled peptide receptor activity 2/521 122/18639 0.0163934426229508 0.586482489537774 0.859007060376382 0.912399434863404 GO:0008080 N-acetyltransferase activity 1/521 69/18639 0.0144927536231884 0.518484519736293 0.859112697904755 0.912399434863404 GO:0098960 postsynaptic neurotransmitter receptor activity 1/521 69/18639 0.0144927536231884 0.518484519736293 0.859112697904755 0.912399434863404 GO:0016782 transferase activity, transferring sulphur-containing groups 1/521 70/18639 0.0142857142857143 0.511077598025775 0.863065432659285 0.915438556259343 GO:0005244 voltage-gated monoatomic ion channel activity 3/521 173/18639 0.0173410404624277 0.620383211476374 0.86573017155216 0.917105573146796 GO:0022832 voltage-gated channel activity 3/521 175/18639 0.0171428571428571 0.61329311763093 0.870782938801429 0.920592720227168 GO:0019783 ubiquitin-like protein peptidase activity 2/521 127/18639 0.015748031496063 0.563392627744948 0.873826917801344 0.920592720227168 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/521 73/18639 0.0136986301369863 0.490074409065811 0.87427178015695 0.920592720227168 GO:0043021 ribonucleoprotein complex binding 3/521 177/18639 0.0169491525423729 0.606363251894987 0.875667182695685 0.920592720227168 GO:0001653 peptide receptor activity 2/521 128/18639 0.015625 0.558991122840691 0.876613408464162 0.920592720227168 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/521 128/18639 0.015625 0.558991122840691 0.876613408464162 0.920592720227168 GO:0003678 DNA helicase activity 1/521 74/18639 0.0135135135135135 0.483451781916273 0.877799971611126 0.920592720227168 GO:0003684 damaged DNA binding 1/521 74/18639 0.0135135135135135 0.483451781916273 0.877799971611126 0.920592720227168 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/521 130/18639 0.0153846153846154 0.550391259412373 0.88201697963567 0.923860481790671 GO:0004842 ubiquitin-protein transferase activity 9/521 449/18639 0.0200445434298441 0.717102197675363 0.884262931953489 0.924219253480608 GO:0098631 cell adhesion mediator activity 1/521 76/18639 0.0131578947368421 0.470729366602687 0.884562646656648 0.924219253480608 GO:0015370 solute:sodium symporter activity 1/521 79/18639 0.0126582278481013 0.45285356787094 0.894012688593049 0.931772230719961 GO:0016835 carbon-oxygen lyase activity 1/521 79/18639 0.0126582278481013 0.45285356787094 0.894012688593049 0.931772230719961 GO:0016779 nucleotidyltransferase activity 2/521 136/18639 0.0147058823529412 0.526109292085356 0.896942335179711 0.933308786895091 GO:0008234 cysteine-type peptidase activity 3/521 187/18639 0.0160427807486631 0.573937409547661 0.897711789063574 0.933308786895091 GO:0004527 exonuclease activity 1/521 84/18639 0.0119047619047619 0.425897998354812 0.908077982091821 0.942917607642374 GO:0140097 catalytic activity, acting on DNA 6/521 336/18639 0.0178571428571429 0.638846997532218 0.91123895963198 0.9450302683946 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/521 88/18639 0.0113636363636364 0.406538998429593 0.917976193743851 0.950842008087767 GO:0008509 monoatomic anion transmembrane transporter activity 2/521 149/18639 0.0134228187919463 0.48020713908462 0.923451450971946 0.955333868514751 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/521 91/18639 0.010989010989011 0.393136613865981 0.924695124854676 0.955442376543194 GO:0008168 methyltransferase activity 3/521 204/18639 0.0147058823529412 0.526109292085356 0.927243079816419 0.95689661004425 GO:0042562 hormone binding 1/521 94/18639 0.0106382978723404 0.380589700657492 0.9308646482163 0.959453857313852 GO:0016407 acetyltransferase activity 1/521 96/18639 0.0104166666666667 0.372660748560461 0.934694737097291 0.961881829338918 GO:0030594 neurotransmitter receptor activity 1/521 97/18639 0.0103092783505155 0.368818885173239 0.936529609662265 0.961881829338918 GO:0003730 mRNA 3'-UTR binding 4/521 262/18639 0.0152671755725191 0.546189799416858 0.937514653385801 0.961881829338918 GO:0046873 metal ion transmembrane transporter activity 8/521 450/18639 0.0177777777777778 0.636007677543186 0.937806122049148 0.961881829338918 GO:0016741 transferase activity, transferring one-carbon groups 3/521 215/18639 0.013953488372093 0.499192072490291 0.941951184761067 0.964953655695403 GO:0022836 gated channel activity 5/521 318/18639 0.0157232704402516 0.562506790279941 0.945081837904239 0.966980075611776 GO:0015103 inorganic anion transmembrane transporter activity 2/521 165/18639 0.0121212121212121 0.4336415983249 0.947292111291783 0.968061000455306 GO:0015399 primary active transmembrane transporter activity 2/521 166/18639 0.0120481927710843 0.43102929953981 0.948519394333249 0.96813597548126 GO:0000149 SNARE binding 1/521 106/18639 0.00943396226415094 0.337504074167964 0.950892528476096 0.969378895979884 GO:0043022 ribosome binding 1/521 112/18639 0.00892857142857143 0.319423498766109 0.95861578902282 0.976066319162798 GO:0016853 isomerase activity 2/521 180/18639 0.0111111111111111 0.397504798464491 0.963081810484926 0.979425016965883 GO:0015276 ligand-gated monoatomic ion channel activity 2/521 186/18639 0.010752688172043 0.384682063030153 0.968030717770058 0.981228936647664 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/521 122/18639 0.00819672131147541 0.293241244768887 0.968888167652788 0.981228936647664 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/521 122/18639 0.00819672131147541 0.293241244768887 0.968888167652788 0.981228936647664 GO:0022834 ligand-gated channel activity 2/521 188/18639 0.0106382978723404 0.380589700657492 0.969533716902161 0.981228936647664 GO:0031072 heat shock protein binding 1/521 131/18639 0.00763358778625954 0.273094899708429 0.975937022816349 0.986016218664778 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/521 132/18639 0.00757575757575758 0.271025998953062 0.976614395364041 0.986016218664778 GO:0099094 ligand-gated monoatomic cation channel activity 1/521 136/18639 0.00735294117647059 0.263054646042678 0.979138824317436 0.987376771156646 GO:0140767 enzyme-substrate adaptor activity 1/521 139/18639 0.00719424460431655 0.257377207638879 0.980851962308944 0.987916922421613 GO:0140098 catalytic activity, acting on RNA 5/521 387/18639 0.0129198966408269 0.462214881935455 0.984770886764737 0.990674788963566 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/521 229/18639 0.00873362445414847 0.312449186565976 0.988842322876353 0.993579292087736 GO:0015081 sodium ion transmembrane transporter activity 1/521 164/18639 0.00609756097560976 0.218142877206123 0.990629449437694 0.994184339806489 GO:0042393 histone binding 2/521 247/18639 0.00809716599190283 0.289679610217038 0.99288543589252 0.99525792199979 GO:0045182 translation regulator activity 2/521 356/18639 0.00561797752808989 0.200985572257327 0.999571056369458 0.999918219943194 GO:0030371 translation repressor activity 1/521 329/18639 0.00303951367781155 0.108739914473569 0.999918219943194 0.999918219943194