category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	38/208	238/9376	7.19715578539108	CFD/RPL3/JUN/RPL18A/RPL12/RPS9/RPS2/RPS4X/RPL5/RPL10/RPL6/PLCG2/RPL13A/FOS/C1R/RPS3/RPL10A/RPL7A/RPS5/RPS27/RPS18/RPL17/PRKCA/C1S/RPS3A/ACE2/STAT3/RPS26/RPL23A/NRP1/RPL29/RPL37/RPS6/RPL14/RPL7/RPSA/RPS23/RPL18	14.5859700915649
Genetic Information Processing	Translation	hsa03010	Ribosome	29/208	222/9376	5.88842688842689	RPL3/RPL18A/RPL12/RPS9/RPS2/RPS4X/RPL5/RPL10/RACK1/RPL6/RPL13A/RPS3/RPL10A/RPL7A/RPS5/RPS27/RPS18/RPL17/RPS3A/RPS26/RPL23A/RPL29/RPL37/RPS6/RPL14/RPL7/RPSA/RPS23/RPL18	11.1024841229929
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	17/208	89/9376	8.61019878997407	COL6A1/COL6A2/COL1A2/COL6A3/LAMA2/COL1A1/LAMB1/COL4A2/CD44/FN1/TNXB/THBS2/SPP1/ITGAV/HSPG2/COL4A1/GP1BB	10.8650889282051
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	23/208	203/9376	5.10723758999621	COL6A1/JUN/COL6A2/COL1A2/COL6A3/LAMA2/COL1A1/PAK3/LAMB1/ACTG1/COL4A2/FN1/TNXB/PRKCA/THBS2/SPP1/BRAF/ITGAV/FYN/COL4A1/PDGFRB/CCND2/PTK2	8.91091193516627
NA	NA	hsa04518	Integrin signaling	19/208	154/9376	5.56143856143856	COL6A1/COL6A2/COL1A2/COL6A3/LAMA2/COL1A1/LAMB1/ACTG1/COL4A2/FN1/TNXB/THBS2/SPP1/ITGAV/COL4A1/PDGFRB/CCND2/PTK2/ITGAX	8.59665770177136
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	26/208	362/9376	3.23756906077348	COL6A1/COL6A2/COL1A2/COL6A3/LAMA2/COL1A1/LAMB1/COL4A2/FN1/MCL1/CSH1/TNXB/PRKCA/THBS2/FGF7/MAGI2/EFNA5/FGF10/SPP1/MYC/ITGAV/RPS6/COL4A1/PDGFRB/CCND2/PTK2	6.53961166928499
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	20/208	233/9376	3.86926378342687	COL6A1/COL3A1/FBLN1/COL6A2/VCAN/COL1A2/COL6A3/LAMA2/COL1A1/ACTG1/COL4A2/FN1/THBS2/DIAPH2/SYNPO2/ITGAV/TTN/SPTAN1/HSPG2/COL4A1	6.68011717727919
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	12/208	101/9376	5.35567402894136	COL3A1/JUN/COL1A2/EGR1/COL1A1/PLCG2/COL4A2/FN1/PRKCA/FOXO1/STAT3/COL4A1	6.62886388700541
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	12/208	103/9376	5.25168035847648	COL6A1/COL3A1/COL15A1/COL6A2/COL1A2/COL6A3/COL1A1/SLC8A1/COL4A2/COL18A1/ACE2/COL4A1	6.53505267682886
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	12/208	103/9376	5.25168035847648	COL3A1/COL1A2/LAMA2/COL1A1/LAMB1/COL4A2/FN1/PRKCA/RAB7A/COL4A1/PTK2/RAB7B	6.53505267682886
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	15/208	178/9376	3.79861711322385	SFRP2/JUN/APCDD1/SERPINF1/TCF7/PRKCA/PRICKLE2/ROR2/MYC/TLE4/SFRP4/TBL1X/EP300/ROR1/CCND2	5.67788755333109
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	16/208	204/9376	3.53544494720965	COL1A2/DDX5/COL1A1/PLCG2/ACTG1/CD44/FN1/PRKCA/MYC/BRAF/ITGAV/STAT3/RPS6/HSPG2/PTK2/ITPR2	5.51464104718828
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	21/208	333/9376	2.84268884268884	COL6A1/COL6A2/COL1A2/COL6A3/LAMA2/COL1A1/LAMB1/COL4A2/FN1/TCF7/TNXB/THBS2/FOXO1/SPP1/ITGAV/EP300/COL4A1/PDGFRB/CHD4/CCND2/PTK2	5.15700866280299
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	10/208	93/9376	4.84698097601323	LAMA2/LAMB1/COL4A2/FN1/GADD45A/MYC/ITGAV/FHIT/COL4A1/PTK2	5.61561520236518
NA	NA	hsa04517	IgSF CAM signaling	17/208	299/9376	2.56290198096218	NLGN1/PAK3/PLCG2/ACTG1/PRKCA/FOXO1/MAGI2/ROBO1/SLIT3/TUBB4B/NRP1/FYN/SPTAN1/PTK2/ITGAX/TRIO/PTPRF	4.13691094004455
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	10/208	122/9376	3.69482976040353	PLCG2/FOS/CSH1/PRKCA/CACNA1D/STAT3/EP300/CACNA1C/PTK2/ITPR2	4.51259653898101
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	7/208	65/9376	4.85443786982249	TRPC4/PRKCA/SPP1/CGA/CACNA1D/CACNA1C/ITPR2	4.6967729697471
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	8/208	86/9376	4.19320214669052	JUN/PAK3/PLCG2/PRKCA/CBLB/MYC/BRAF/PTK2	4.4807197816756
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	8/208	86/9376	4.19320214669052	LAMA2/SLC8A1/ACTG1/CACNB2/TCF7/ITGAV/CACNA1D/CACNA1C	4.4807197816756
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	14/208	232/9376	2.72015915119363	TMSB4X/CXCL12/PAK3/ACTG1/GSN/FN1/FGF7/DIAPH2/FGF10/BRAF/ITGAV/PDGFRB/PTK2/ITGAX	3.99599114651503
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	12/208	184/9376	2.93979933110368	SEMA5A/CXCL12/PAK3/PLCG2/TRPC4/PRKCA/EFNA5/ROBO1/SLIT3/NRP1/FYN/PTK2	4.00258637125543
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	8/208	99/9376	3.64257964257964	LAMA2/SLC8A1/ACTG1/CACNB2/ITGAV/CACNA1D/TTN/CACNA1C	3.98127253037989
Organismal Systems	Immune system	hsa04611	Platelet activation	9/208	126/9376	3.21978021978022	COL3A1/COL1A2/COL1A1/PLCG2/ACTG1/PRKG1/FYN/GP1BB/ITPR2	3.77836915062267
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	8/208	105/9376	3.43443223443223	LAMA2/SLC8A1/ACTG1/CACNB2/ITGAV/CACNA1D/TTN/CACNA1C	3.77840974149756
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	7/208	93/9376	3.39288668320926	JUN/EGR1/PRKCA/CGA/CACNA1D/CACNA1C/ITPR2	3.49300683303429
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	6/208	73/9376	3.70495258166491	PLCG2/PRKCA/GADD45A/BRAF/STAT3/FHIT	3.49453648559677
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	8/208	122/9376	2.95586380832283	PLCG2/ACTG1/PRKCA/FOXO1/MYC/ITGAV/EP300/MED13L	3.2751695048945
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	14/208	300/9376	2.10358974358974	JUN/FOS/CACNB2/PRKCA/GADD45A/FGF7/EFNA5/FGF10/DUSP16/MYC/BRAF/CACNA1D/PDGFRB/CACNA1C	2.92618003440916
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	9/208	154/9376	2.63436563436563	JUN/ACTG1/FOS/CACNB2/EEF2/PRKCA/CACNA1D/CACNA1C/ITPR2	3.08018659660489
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	9/208	157/9376	2.58402743753062	PBX1/DUSP16/RAB7A/ITGAV/PLA2G6/LRP1/SLC16A1/PTK2/RAB7B	3.0147452667907
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	8/208	130/9376	2.77396449704142	COL3A1/JUN/COL1A2/COL1A1/FOS/COL4A2/PRKCA/COL4A1	3.06774783913078
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	6/208	80/9376	3.38076923076923	PLCG2/PRKCA/BRAF/STAT3/RPS6/PDGFRB	3.22102607379069
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	4/208	37/9376	4.87318087318087	TCF7/GADD45A/MYC/BRAF	3.5554817699826
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	8/208	133/9376	2.71139386928861	SOD2/FOXO1/GADD45A/HOMER1/BRAF/STAT3/EP300/CCND2	2.99398292523877
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	9/208	168/9376	2.41483516483516	MCL1/CSH1/AOX1/MYC/STAT3/IL15/EP300/PDGFRB/CCND2	2.78713390413185
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	6/208	87/9376	3.10875331564987	JUN/FOS/TCF7/GADD45A/MYC/BRAF	2.97632893659456
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	14/208	323/9376	1.95379852345797	ZEB1/PLCG2/CD44/MCL1/CYP1B1/TNXB/PRKCA/EFNA5/MYC/STAT3/EP300/ZFPM2/PDGFRB/CCND2	2.62749349882581
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	7/208	115/9376	2.7438127090301	EGR1/NACA/FOS/PRKCA/AKAP13/BRAF/ITPR2	2.83399983061018
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	10/208	201/9376	2.24263298890165	ZEB1/NFKBIZ/PBX1/DDX5/MEIS1/FOXO1/GADD45A/MYC/CCND2/PTK2	2.68236500502953
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	5/208	65/9376	3.46745562130178	PBX1/PDE8B/CACNA1D/CACNA1C/ITPR2	3.00668456921176
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	5/208	67/9376	3.36394948335247	PRKCA/BRAF/EP300/CACNA1C/ITPR2	2.92485325181395
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	8/208	148/9376	2.43659043659044	JUN/FOS/TCF7/GADD45A/FGF7/FGF10/MYC/BRAF	2.65332249581989
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	5/208	69/9376	3.26644370122631	JUN/FOS/PRKCA/CACNA1D/CACNA1C	2.84606377359896
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	11/208	248/9376	1.99937965260546	JUN/PAK3/ACTG1/FOS/RPS3/TCF7/MYC/RAB7A/TUBB4B/EXOC4/RAB7B	2.40241776708134
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	10/208	217/9376	2.07727756114853	JUN/FOS/CYP1B1/PRKCA/FGF7/FGF10/MYC/CACNA1D/STAT3/CACNA1C	2.41831825775198
Human Diseases	Cancer: specific types	hsa05218	Melanoma	5/208	73/9376	3.08746048472076	GADD45A/FGF7/FGF10/BRAF/PDGFRB	2.69679656329069
Human Diseases	Cancer: specific types	hsa05214	Glioma	5/208	76/9376	2.96558704453441	PLCG2/PRKCA/GADD45A/BRAF/PDGFRB	2.59141880652151
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	8/208	163/9376	2.21236432279377	JUN/FOS/PRKCA/MYC/BRAF/STAT3/EP300/HSPG2	2.351832662204
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	7/208	134/9376	2.35476463834673	PRKG1/PRKCA/BRAF/CACNA1D/PLA2G6/CACNA1C/ITPR2	2.37910315410486
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	6/208	106/9376	2.55152394775036	ZEB1/TCF7/FOXO1/BRAF/EP300/PDGFRB	2.41964443957908
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	7/208	137/9376	2.30320044918585	JUN/ACTG1/FOS/MCL1/GADD45A/SPTAN1/ITPR2	2.31440321742645
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	6/208	110/9376	2.45874125874126	PLCG2/PRKCA/LDHA/STAT3/EP300/RPS6	2.3179734893938
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	10/208	238/9376	1.8939883645766	PAK3/PLCG2/PRKCA/FGF7/EFNA5/FGF10/RASAL2/GAB2/PLA2G6/PDGFRB	2.10414067347807
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	4/208	59/9376	3.05606258148631	TCF7/GADD45A/MYC/BRAF	2.38618598626216
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	6/208	115/9376	2.35183946488294	FOS/PRKCA/CACNA1D/FYN/CACNA1C/ITPR2	2.1969749358125
Organismal Systems	Nervous system	hsa04730	Long-term depression	4/208	60/9376	3.0051282051282	PRKG1/PRKCA/BRAF/ITPR2	2.34683758372491
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/208	87/9376	2.59062776304156	SLC8A1/CACNB2/MT-CO3/CACNA1D/CACNA1C	2.24503805322164
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	9/208	212/9376	1.91364296081277	MAGI3/ACTG1/PRKCA/FGF7/MAGI2/EFNA5/FGF10/BRAF/PDGFRB	2.02666471397994
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	5/208	89/9376	2.5324114088159	PRKG1/PRKCA/TUBB4B/PDGFRB/ITPR2	2.18782540257896
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	5/208	89/9376	2.5324114088159	PRKCA/CACNA1D/PLCL1/CACNA1C/GPHN	2.18782540257896
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	4/208	62/9376	2.90818858560794	TLE4/DTX4/EP300/ATXN1	2.27053930847864
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	5/208	93/9376	2.42349048800662	ACTG1/TCF7/FYN/EP300/PTPRF	2.07793458681369
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	10/208	254/9376	1.77468201090248	SLC8A1/PLCG2/PRKCA/FGF7/SLC25A6/FGF10/CACNA1D/PDGFRB/CACNA1C/ITPR2	1.88527756297925
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	7/208	155/9376	2.03573200992556	ACTG1/C1R/THBS2/RAB7A/ITGAV/TUBB4B/RAB7B	1.95841280473339
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	7/208	155/9376	2.03573200992556	PBX1/TCF7/PDE8B/BRAF/CACNA1D/CACNA1C/ITPR2	1.95841280473339
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	7/208	157/9376	2.00979911807937	FOXO1/GADD45A/SLC25A6/MYC/CACNA1D/CCND2/ITPR2	1.92186513914495
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	9/208	224/9376	1.81112637362637	JUN/EGR1/FOS/SLC25A6/MYC/IL15/NRP1/EP300/CCND2	1.85069362703225
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	4/208	68/9376	2.65158371040724	TCF7/MYC/BRAF/STAT3	2.05876541129339
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	5/208	97/9376	2.32355273592387	FOS/PRKG1/PRKCA/CACNA1D/CACNA1C	1.97358816994492
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	9/208	227/9376	1.7871907827855	CXCL12/PRKCA/MYC/CCL4L2/AKAP13/ITGAV/STAT3/PTK2/ITPR2	1.80836510650417
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	9/208	227/9376	1.7871907827855	JUN/SOD2/MT-ATP8/FOS/CYP1B1/SLC25A6/MT-CO3/BRAF/PTK2	1.80836510650417
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	5/208	98/9376	2.29984301412873	PLCG2/GSN/PRKCA/GAB2/PLA2G6	1.94830417680029
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	4/208	69/9376	2.61315496098105	PLCG2/PRKCA/GAB2/FYN	2.02570304003822
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	5/208	99/9376	2.27661227661228	JUN/FOS/PRKCA/PDGFRB/SLC22A3	1.92332571814589
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	4/208	70/9376	2.57582417582418	JUN/PAK3/BRAF/EP300	1.99322010120174
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	8/208	196/9376	1.83987441130298	JUN/PLCG2/FOS/TCF7/MYC/STAT3/EP300/ITPR2	1.7897857589007
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	4/208	71/9376	2.53954496208017	FOS/CGA/STAT3/CCND2	1.96129700840022
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/208	21/9376	4.29304029304029	CHSY3/UST	2.2754369151683
Human Diseases	Infectious disease: viral	hsa05162	Measles	6/208	136/9376	1.98868778280543	JUN/RACK1/FOS/CBLB/STAT3/CCND2	1.74933360690649
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	5/208	105/9376	2.14652014652015	JUN/RABGEF1/ARIH1/RAB7A/RAB7B	1.77947976089187
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	7/208	170/9376	1.85610859728507	PLCG2/ACTG1/TCF7/PRKCA/GADD45A/MYC/BRAF	1.69667178269267
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	8/208	205/9376	1.75909943714822	COL3A1/COL1A2/MT-ATP8/COL1A1/GFPT2/PRKCA/SLC25A6/MT-CO3	1.65518772375989
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	4/208	77/9376	2.34165834165834	GADD45A/MYC/BRAF/GAB2	1.78052951550904
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	2/208	23/9376	3.91973244147157	ACE2/ENPEP	2.11159930110612
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	4/208	78/9376	2.31163708086785	JUN/FOS/C1R/C1S	1.75204888597188
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	6/208	142/9376	1.90465872156013	JUN/PLCG2/FOS/GAB2/FYN/ITPR2	1.63611571056367
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	3/208	51/9376	2.65158371040724	PLCG2/ACTG1/PRKCA	1.78131720235954
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	5/208	115/9376	1.95986622073579	PRKCA/BRAF/CACNA1D/CACNA1C/ITPR2	1.55995004101481
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	4/208	83/9376	2.17238183503244	AUTS2/MBD5/EP300/SFMBT2	1.61588392966315
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	5/208	116/9376	1.94297082228117	CXCL12/PLCG2/ACTG1/PRKCA/PTK2	1.53922376295602
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	5/208	116/9376	1.94297082228117	PRKCA/HOMER1/CACNA1D/CACNA1C/ITPR2	1.53922376295602
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	6/208	150/9376	1.80307692307692	TCF7/GADD45A/FGF7/FGF10/MYC/BRAF	1.49339968064457
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	3/208	56/9376	2.41483516483516	EEF1A1/EEF1G/CLK1	1.59945455875456
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	8/208	226/9376	1.59564329475834	JUN/FOS/PDE10A/BRAF/CGA/CACNA1D/EP300/CACNA1C	1.36524292041574
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	4/208	88/9376	2.04895104895105	CFD/C1R/C1S/ITGAX	1.48907117810107
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	5/208	122/9376	1.84741488020177	JUN/PAK3/FOS/CBLB/FYN	1.41902895376473
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	3/208	60/9376	2.25384615384615	PLCG2/PRKCA/PTK2	1.4675237575978
Organismal Systems	Digestive system	hsa04970	Salivary secretion	4/208	93/9376	1.93879239040529	PRKG1/PRKCA/CST3/ITPR2	1.37039846370339
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	7/208	200/9376	1.57769230769231	JUN/PAK3/ACTG1/FOS/RPS3/TUBB4B/FYN	1.24384104394901
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	2/208	32/9376	2.81730769230769	LDHA/PCCA	1.55101873058225
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	9/208	275/9376	1.47524475524476	EGR1/MT-ATP8/SLC25A6/MT-CO3/CACNA1D/TUBB4B/FYN/CACNA1C/ITPR2	1.20481155989175
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	4/208	95/9376	1.89797570850202	JUN/CXCL12/FOS/IL15	1.32497904018341
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	6/208	166/9376	1.62928637627433	SLC8A1/PRKG1/SLC25A6/CACNA1D/CACNA1C/ITPR2	1.23211873668516
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	7/208	205/9376	1.53921200750469	JUN/PLCG2/CD44/GADD45A/MYC/STAT3/CCND2	1.17573146764358
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	4/208	98/9376	1.83987441130298	PLCG2/INPP4B/PRKCA/ITPR2	1.25886803694222
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	4/208	98/9376	1.83987441130298	PRKCA/CACNA1D/CACNA1C/ITPR2	1.25886803694222
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	5/208	133/9376	1.69462116830538	FOS/PRKCA/CACNA1D/CACNA1C/ITPR2	1.21519888246427
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	4/208	99/9376	1.82128982128982	JUN/FOS/BRAF/PTK2	1.23734344740122
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	4/208	99/9376	1.82128982128982	PLCG2/PRKCA/PLA2G6/ITPR2	1.23734344740122
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/208	66/9376	2.04895104895105	RORA/JUN/STAT3	1.28804890348639
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	5/208	138/9376	1.63322185061316	FOXO1/CBLB/BRAF/RPS6/PTPRF	1.12872062329699
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	5/208	138/9376	1.63322185061316	JUN/ACTG1/FOS/FN1/PTK2	1.12872062329699
Organismal Systems	Endocrine system	hsa04924	Renin secretion	3/208	69/9376	1.95986622073579	CACNA1D/CACNA1C/ITPR2	1.20534230647748
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	2/208	37/9376	2.43659043659044	UAP1/GFPT2	1.31875357115297
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	7/208	214/9376	1.4744787922358	JUN/PAK3/PLCG2/FOS/PRKCA/PTK2/ITPR2	1.05756860990585
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	5/208	140/9376	1.60989010989011	EGR1/SLC8A1/SPP1/RPS6/ITPR2	1.09509967453209
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/208	70/9376	1.93186813186813	LAMA2/ACTG1/FYN	1.17869640573158
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	4/208	105/9376	1.71721611721612	CXCL12/PLCG2/GADD45A/CCL4L2	1.11316976735664
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	4/208	105/9376	1.71721611721612	JUN/PLCG2/CBLB/ITPR2	1.11316976735664
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	2/208	38/9376	2.37246963562753	UAP1/GFPT2	1.27687272978617
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/208	142/9376	1.58721560130011	JUN/ACTG1/FOS/ITGAV/PTK2	1.0620056468569
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	3/208	71/9376	1.90465872156013	LDHA/MYC/PDGFRB	1.15248627868697
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	4/208	107/9376	1.68511861969806	FOXO1/LDHA/EP300/ITPR2	1.07354739336571
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	5/208	144/9376	1.56517094017094	RORA/PRKCA/SLC25A6/ATXN1/ITPR2	1.02942135857405
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	4/208	108/9376	1.66951566951567	EEF1A1/NUP153/NUP58/NXF1	1.0540461210323
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	3/208	73/9376	1.85247629083246	NUP153/EP300/AFF4	1.10131671867853
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/208	109/9376	1.65419901199718	JUN/FOS/SPP1/CCL4L2	1.0347455198965
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/208	109/9376	1.65419901199718	RORA/JUN/FOS/STAT3	1.0347455198965
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/208	109/9376	1.65419901199718	GFPT2/FOXO1/STAT3/PTPRF	1.0347455198965
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/208	41/9376	2.19887429643527	MYC/BRAF	1.1587464582521
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/208	75/9376	1.80307692307692	PRKCA/CGA/ITPR2	1.05172684486809
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	5/208	149/9376	1.5126484254001	PLCG2/PRKCA/GAB2/FYN/PDGFRB	0.950085095312726
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/208	76/9376	1.77935222672065	ACTG1/PRKCA/ITPR2	1.02749355356414
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/208	42/9376	2.14652014652015	CYP1B1/AOX1	1.12163729352447
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/208	77/9376	1.75624375624376	GADD45A/BRAF/STAT3	1.00361939183942
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	3/208	78/9376	1.73372781065089	PABPC1/TOB2/BTG1	0.980093512152691
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/208	78/9376	1.73372781065089	ACTG1/FN1/PTK2	0.980093512152691
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/208	78/9376	1.73372781065089	EEF1A1/JUN/FOS	0.980093512152691
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	5/208	154/9376	1.46353646353646	SLC8A1/CACNB2/PRKCA/CACNA1D/CACNA1C	0.873598154538307
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	6/208	193/9376	1.40135512156238	CXCL12/PLCG2/CCL4L2/BRAF/STAT3/PTK2	0.848584656605879
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	5/208	158/9376	1.42648490749757	GADD45A/MYC/EP300/STAG1/CCND2	0.814317675894869
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/208	47/9376	1.91816693944354	CACNA1D/CACNA1C	0.950458232689399
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	2/208	48/9376	1.87820512820513	AOX1/PCCA	0.918760514221557
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	3/208	86/9376	1.57245080500894	PRKCA/CACNA1D/CACNA1C	0.803266291392825
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	6/208	205/9376	1.31932457786116	JUN/GSN/STAT3/EP300/CHD4/CCND2	0.696275211527269
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/208	50/9376	1.80307692307692	CXCL12/IL15	0.857579609499885
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/208	50/9376	1.80307692307692	THBS2/LRP1	0.857579609499885
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	4/208	128/9376	1.40865384615385	PRPS2/PDE8B/PDE10A/FHIT	0.701159250960444
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/208	52/9376	1.73372781065089	CYP1B1/CGA	0.799126482843984
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/208	90/9376	1.5025641025641	JUN/FOS/STAT3	0.72156985723888
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/208	91/9376	1.48605240912933	JUN/PLCG2/FOS	0.70176684410869
Human Diseases	Substance dependence	hsa05032	Morphine addiction	3/208	91/9376	1.48605240912933	PDE8B/PDE10A/PRKCA	0.70176684410869
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/208	53/9376	1.70101596516691	SLC8A1/PRKCA	0.770846677593648
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/208	253/9376	1.24718759501368	JUN/PLCG2/ACTG1/CD44/FOXO1/PTK2/ITPR2	0.600341130403302
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	2/208	54/9376	1.66951566951567	LDHA/MAT2A	0.743161289778306
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/208	173/9376	1.30280124499778	ACTG1/PRKCA/SLC25A6/EP300/NXF1	0.605474699590814
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	4/208	133/9376	1.3556969346443	PLCG2/PRKCA/BRAF/FYN	0.622270868206098
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	6/208	216/9376	1.25213675213675	JUN/SOD2/FOS/PRKCA/STAT3/PTK2	0.564670755877179
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	2/208	56/9376	1.60989010989011	SCUBE2/CCND2	0.68947361561847
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/208	20/9376	2.25384615384615	UAP1	0.845462105296022
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	8/208	308/9376	1.17082917082917	SOD2/MT-ATP8/TGM2/TAF4B/SLC25A6/MT-CO3/TUBB4B/EP300	0.459157453706841
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/208	21/9376	2.14652014652015	DPYD	0.792226645659263
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/208	99/9376	1.36596736596737	CFD/C1R/C1S	0.551361176656551
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/208	59/9376	1.52803129074316	PRKG1/CGA	0.612812507568912
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	3/208	101/9376	1.33891850723534	TCF7/PRKCA/EP300	0.515797242475504
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/208	61/9376	1.47793190416141	SLC8A1/MT1G	0.564052481114924
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	4/208	144/9376	1.25213675213675	MEIS1/TCF7/MYC/STAT3	0.459250360346835
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	3/208	103/9376	1.31292008961912	PABPC1/SMG6/NXF1	0.480974367045721
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/208	62/9376	1.45409429280397	SOD2/FOXO1	0.54032339850662
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	2/208	63/9376	1.43101343101343	PTGDS/PLA2G6	0.517006829760687
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	2/208	63/9376	1.43101343101343	TCF7/GADD45A	0.517006829760687
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/208	149/9376	1.21011874032008	PRKCA/CACNA1D/CACNA1C/ITPR2	0.389410507343685
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	5/208	195/9376	1.15581854043392	PLCG2/ACTG1/PRKCA/SLC25A6/ATG7	0.331185601508774
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/208	26/9376	1.73372781065089	PLA2G6	0.56428155240406
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/208	110/9376	1.22937062937063	THSD4/MYC/EP300	0.36447521789126
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	2/208	68/9376	1.32579185520362	ALDH1A3/AOX1	0.406112629077053
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/208	112/9376	1.20741758241758	LAMA2/LAMB1/STAT3	0.332610005548556
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/208	157/9376	1.1484566389025	ACTG1/TCF7/MYC/CCND2	0.282544947676332
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/208	28/9376	1.60989010989011	GPHN	0.48680077165418
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/208	71/9376	1.26977248104009	JUN/PLCG2	0.343675548973719
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	4/208	160/9376	1.12692307692308	VCAN/NLGN1/ITGAV/PTPRF	0.243898625908587
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	1/208	29/9376	1.55437665782493	RASSF4	0.450347562921282
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/208	30/9376	1.5025641025641	PLA2G6	0.415259146226621
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	9/208	388/9376	1.04559873116574	MT-ATP8/SLC25A6/MT-CO3/BRAF/CACNA1D/TUBB4B/CACNA1C/LRP1/ITPR2	0.13817106097056
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/208	119/9376	1.13639301874596	JUN/FOS/IL15	0.225533206137419
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/208	75/9376	1.20205128205128	PRPS2/MAT2A	0.264610713204359
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/208	75/9376	1.20205128205128	GADD45A/CCND2	0.264610713204359
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/208	120/9376	1.12692307692308	JUN/PLCG2/BRAF	0.210765510779827
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/208	31/9376	1.45409429280397	PRPS2	0.381432101806004
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/208	31/9376	1.45409429280397	DPYD	0.381432101806004
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/208	31/9376	1.45409429280397	PCCA	0.381432101806004
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/208	32/9376	1.40865384615385	ATG7	0.348774053173257
Human Diseases	Immune disease	hsa05310	Asthma	1/208	32/9376	1.40865384615385	PRG2	0.348774053173257
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/208	78/9376	1.15581854043392	PLCG2/INPP4B	0.208138138333502
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/208	33/9376	1.36596736596737	VAMP5	0.317202176878495
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	3/208	125/9376	1.08184615384615	PRKCA/GAB2/FYN	0.138751901980235
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/208	34/9376	1.32579185520362	RORA	0.286641952327024
NA	NA	hsa04081	Hormone signaling	5/208	219/9376	1.02915349490692	PRKG1/CSH1/ITGAV/CGA/STAT3	0.0657530766847691
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/208	36/9376	1.25213675213675	GBE1	0.228293722613373
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/208	36/9376	1.25213675213675	GALNT13	0.228293722613373
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/208	37/9376	1.21829521829522	GFPT2	0.20038947173815
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/208	37/9376	1.21829521829522	AOX1	0.20038947173815
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/208	37/9376	1.21829521829522	PRKCA	0.20038947173815
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/208	38/9376	1.18623481781377	AOX1	0.173262966283669
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/208	38/9376	1.18623481781377	PRKCA	0.173262966283669
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/208	39/9376	1.15581854043392	MAT2A	0.146868195670213
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	2/208	90/9376	1.0017094017094	SOD2/FOXO1	0.00245431924230915
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/208	139/9376	0.972883231876038	JUN/FOS/ITPR2	-0.0485131929510593
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	5/208	235/9376	0.959083469721768	MT-ATP8/ACTG1/PRKG1/MT-CO3/RPS6	-0.0956788349609409
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/208	42/9376	1.07326007326007	ATG7	0.0716701146022025
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/208	93/9376	0.969396195202647	JUN/FOS	-0.0446737825172033
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/208	94/9376	0.959083469721768	JUN/FOS	-0.0600512354321612
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	10/208	480/9376	0.939102564102564	MT-ATP8/PRKCA/SLC25A6/MT-CO3/BRAF/CACNA1D/TUBB4B/ATXN1/CACNA1C/ITPR2	-0.206301431677534
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/208	44/9376	1.02447552447552	MGAT4C	0.0245104329940226
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/208	44/9376	1.02447552447552	TAF4B	0.0245104329940226
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/208	44/9376	1.02447552447552	POLG2	0.0245104329940226
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/208	47/9376	0.959083469721768	LDHA	-0.0423555362161052
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/208	100/9376	0.901538461538462	CXCL12/CCL4L2	-0.14909608875282
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/208	100/9376	0.901538461538462	CD44/GP1BB	-0.14909608875282
NA	NA	hsa03272	Virion - Hepatitis viruses	1/208	48/9376	0.939102564102564	HSPG2	-0.0637096706941956
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/208	48/9376	0.939102564102564	CACNA1D	-0.0637096706941956
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/208	102/9376	0.883861236802413	PRKCA/ITPR2	-0.177633036681379
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/208	49/9376	0.919937205651491	GALNT13	-0.0846326225497309
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/208	49/9376	0.919937205651491	JUN	-0.0846326225497309
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/208	103/9376	0.875280059746079	JUN/FOS	-0.191701000707961
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/208	50/9376	0.901538461538462	P4HA1	-0.105143860168568
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	3/208	156/9376	0.866863905325444	MYC/BRAF/STAT3	-0.252564702751861
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/208	157/9376	0.861342479176874	JUN/FOS/MT-CO3	-0.263895116146541
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/208	51/9376	0.883861236802413	PLA2G6	-0.125261574960443
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/208	158/9376	0.85589094449854	PRKCA/BRAF/RPS6	-0.275157570850321
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/208	52/9376	0.866863905325444	LRP1	-0.145002789225723
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/208	54/9376	0.834757834757835	REV3L	-0.18341853109422
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/208	54/9376	0.834757834757835	CGA	-0.18341853109422
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/208	368/9376	0.857441471571906	MT-ATP8/ACTG1/MT-CO3/NUP153/TUBB4B/NUP58/NXF1	-0.420226008021436
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	5/208	268/9376	0.840987370838117	MT-ATP8/SLC25A6/MT-CO3/TUBB4B/ITPR2	-0.397802499700898
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/208	56/9376	0.804945054945055	MGAT4C	-0.220507327517619
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	3/208	169/9376	0.800182066454256	RAB7A/ATG7/RAB7B	-0.394819639310575
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/208	170/9376	0.795475113122172	JUN/ACTG1/CACNA1D	-0.40533596499846
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	2/208	116/9376	0.777188328912467	PRPS2/PCCA	-0.363698441879903
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/208	59/9376	0.764015645371578	DPYD	-0.273874231777711
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/208	117/9376	0.770545693622617	ACTG1/CHD4	-0.376172553459005
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/208	63/9376	0.715506715506715	KMT2C	-0.341253799813711
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/208	122/9376	0.738965952080706	EEF2/FOXO1	-0.43711159736503
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/208	181/9376	0.747131321716957	RAB7A/EP300/ITGAX	-0.517414341986028
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/208	66/9376	0.682983682983683	CYP1B1	-0.389277001942554
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/208	67/9376	0.672789896670494	LDHA	-0.404848555982018
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/208	70/9376	0.643956043956044	STAT3	-0.450350985208762
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/208	70/9376	0.643956043956044	CYP1B1	-0.450350985208762
NA	NA	hsa04519	Cadherin signaling	7/208	404/9376	0.781035795887281	ACTG1/TCF7/PRICKLE2/LHFPL3/EP300/PDGFRB/PTK2	-0.677640222535136
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/208	73/9376	0.617492096944152	AOX1	-0.49416312593363
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/208	194/9376	0.697065820777161	ACTG1/TUBB4B/KIF1B	-0.642185507564306
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	2/208	138/9376	0.653288740245262	MT-ATP8/MT-CO3	-0.61801428493902
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/208	75/9376	0.601025641025641	REV3L	-0.52250541845937
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/208	76/9376	0.593117408906883	PLIN2	-0.536431699393226
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/208	143/9376	0.630446476600323	C1R/C1S	-0.670739606281837
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/208	79/9376	0.570593962999026	CYP1B1	-0.577285008424789
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/208	144/9376	0.626068376068376	TCF7/FOXO1	-0.681091636107594
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/208	82/9376	0.549718574108818	DPYD	-0.6168358806151
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/208	83/9376	0.543095458758109	SOD2	-0.629747650058446
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/208	83/9376	0.543095458758109	CCL4L2	-0.629747650058446
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/208	86/9376	0.524150268336315	CACNA1C	-0.667715104720286
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/208	154/9376	0.585414585414585	MAT2A/GPHN	-0.781343177011632
NA	NA	hsa04382	Cornified envelope formation	3/208	217/9376	0.623183268344559	COL4A2/KAZN/COL4A1	-0.845894145439405
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/208	168/9376	0.536630036630037	SLC25A6/STAT3	-0.912808903230237
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	4/208	298/9376	0.605059370160041	CXCL12/CSH1/CCL4L2/IL15	-1.04357786931525
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/208	104/9376	0.433431952662722	PLA2G6	-0.875108776799633
Genetic Information Processing	Transcription	hsa03040	Spliceosome	3/208	243/9376	0.55650522317189	DDX5/HNRNPC/RBMX	-1.05503027125813
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/208	110/9376	0.40979020979021	BRAF	-0.937856963110436
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	2/208	183/9376	0.492643968053804	RMRP/NXF1	-1.04397415256673
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/208	250/9376	0.540923076923077	CBLB/RAB7A/PSD3	-1.10814154617368
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/208	187/9376	0.482106129164953	JUN/ITPR2	-1.07747561990099
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/208	138/9376	0.326644370122631	ITPR2	-1.20025925435102
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/208	142/9376	0.317443120260022	CBLB	-1.23443460797019
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/208	250/9376	0.360615384615385	RAB7A/NCOA7	-1.54337676471107
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/208	180/9376	0.25042735042735	NXF1	-1.52943317495551
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/208	191/9376	0.236004832863472	BRAF	-1.60674781506088
NA	NA	hsa04082	Neuroactive ligand signaling	1/208	199/9376	0.226517201391573	PRKCA	-1.661142293188
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/208	370/9376	0.243659043659044	CSH1/CGA	-2.23579773805403
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	2/208	449/9376	0.200788076066472	SLC8A1/PRKG1	-2.61404079688506