ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0008201 heparin binding 18/432 172/18639 0.104651162790698 4.51526162790698 1.07099136597979e-07 3.89104131068968e-05 GO:0019838 growth factor binding 16/432 136/18639 0.117647058823529 5.07598039215686 1.08084480852491e-07 3.89104131068968e-05 GO:0005539 glycosaminoglycan binding 21/432 242/18639 0.0867768595041322 3.74405991735537 2.37928484297127e-07 5.71028362313105e-05 GO:0098631 cell adhesion mediator activity 11/432 76/18639 0.144736842105263 6.24479166666667 1.34974265676803e-06 0.000242953678218245 GO:0098632 cell-cell adhesion mediator activity 9/432 55/18639 0.163636363636364 7.06022727272727 4.38995901889811e-06 0.000632154098721328 GO:1901681 sulfur compound binding 19/432 275/18639 0.0690909090909091 2.98098484848485 2.44468723433107e-05 0.00293362468119728 GO:0005201 extracellular matrix structural constituent 14/432 168/18639 0.0833333333333333 3.59548611111111 3.83097221037596e-05 0.00394042855924385 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/432 13/18639 0.307692307692308 13.275641025641 0.000172335205541529 0.0155101684987376 GO:0061134 peptidase regulator activity 15/432 226/18639 0.0663716814159292 2.86366150442478 0.000267264641910369 0.0213811713528296 GO:0004857 enzyme inhibitor activity 22/432 416/18639 0.0528846153846154 2.28175080128205 0.000304021345492934 0.0218895368754912 GO:0051015 actin filament binding 14/432 209/18639 0.0669856459330144 2.89015151515152 0.00038664859511403 0.0253079080438274 GO:0019199 transmembrane receptor protein kinase activity 8/432 78/18639 0.102564102564103 4.42521367521368 0.000443252816356191 0.0265951689813715 GO:0016209 antioxidant activity 8/432 86/18639 0.0930232558139535 4.01356589147287 0.000854338820138718 0.047317226961529 GO:0005007 fibroblast growth factor receptor activity 6/432 50/18639 0.12 5.1775 0.00100405585690812 0.0516371583552748 GO:0045294 alpha-catenin binding 3/432 11/18639 0.272727272727273 11.7670454545455 0.00177602924222663 0.0694841755673866 GO:0048185 activin binding 3/432 11/18639 0.272727272727273 11.7670454545455 0.00177602924222663 0.0694841755673866 GO:0017134 fibroblast growth factor binding 4/432 23/18639 0.173913043478261 7.5036231884058 0.00177642870145496 0.0694841755673866 GO:0004601 peroxidase activity 6/432 57/18639 0.105263157894737 4.54166666666667 0.0020016304525042 0.0694841755673866 GO:0048027 mRNA 5'-UTR binding 4/432 24/18639 0.166666666666667 7.19097222222222 0.00209311585091757 0.0694841755673866 GO:0045296 cadherin binding 17/432 334/18639 0.0508982035928144 2.19604540918164 0.00214662388008229 0.0694841755673866 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 22/432 484/18639 0.0454545454545455 1.96117424242424 0.00218447072341141 0.0694841755673866 GO:0004859 phospholipase inhibitor activity 3/432 12/18639 0.25 10.7864583333333 0.00232752945124229 0.0694841755673866 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/432 12/18639 0.25 10.7864583333333 0.00232752945124229 0.0694841755673866 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/432 59/18639 0.101694915254237 4.38771186440678 0.00239091429946366 0.0694841755673866 GO:0048306 calcium-dependent protein binding 7/432 80/18639 0.0875 3.77526041666667 0.00253878018414297 0.0694841755673866 GO:0001216 DNA-binding transcription activator activity 22/432 491/18639 0.044806517311609 1.93321452817379 0.0026023421628528 0.0694841755673866 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/432 60/18639 0.1 4.31458333333333 0.002605656583777 0.0694841755673866 GO:0001637 G protein-coupled chemoattractant receptor activity 4/432 26/18639 0.153846153846154 6.63782051282051 0.00283930886453314 0.070493185602202 GO:0004950 chemokine receptor activity 4/432 26/18639 0.153846153846154 6.63782051282051 0.00283930886453314 0.070493185602202 GO:0005179 hormone activity 9/432 132/18639 0.0681818181818182 2.94176136363636 0.00366915470030496 0.0853800707063724 GO:0003779 actin binding 20/432 443/18639 0.0451467268623025 1.94789315274643 0.00367608637763548 0.0853800707063724 GO:0001968 fibronectin binding 4/432 30/18639 0.133333333333333 5.75277777777778 0.00483922777008089 0.0894722027116468 GO:0005004 GPI-linked ephrin receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0005008 hepatocyte growth factor receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0005009 insulin receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0005011 macrophage colony-stimulating factor receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0005020 stem cell factor receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0008288 boss receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0036332 placental growth factor receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0038062 protein tyrosine kinase collagen receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0060175 brain-derived neurotrophic factor receptor activity 5/432 49/18639 0.102040816326531 4.40263605442177 0.00539124472818114 0.0894722027116468 GO:0055102 lipase inhibitor activity 3/432 16/18639 0.1875 8.08984375 0.00553063820247131 0.0894722027116468 GO:0008236 serine-type peptidase activity 11/432 194/18639 0.0567010309278351 2.44641323024055 0.00570900363285795 0.0894722027116468 GO:0005006 epidermal growth factor receptor activity 5/432 50/18639 0.1 4.31458333333333 0.00587871015832259 0.0894722027116468 GO:0005017 platelet-derived growth factor receptor activity 5/432 50/18639 0.1 4.31458333333333 0.00587871015832259 0.0894722027116468 GO:0005019 platelet-derived growth factor beta-receptor activity 5/432 50/18639 0.1 4.31458333333333 0.00587871015832259 0.0894722027116468 GO:0030414 peptidase inhibitor activity 10/432 169/18639 0.0591715976331361 2.55300788954635 0.00614816354500522 0.0894722027116468 GO:0005010 insulin-like growth factor receptor activity 5/432 51/18639 0.0980392156862745 4.22998366013072 0.00639639284246194 0.0894722027116468 GO:0005021 vascular endothelial growth factor receptor activity 5/432 51/18639 0.0980392156862745 4.22998366013072 0.00639639284246194 0.0894722027116468 GO:0005030 neurotrophin receptor activity 5/432 51/18639 0.0980392156862745 4.22998366013072 0.00639639284246194 0.0894722027116468 GO:0019955 cytokine binding 9/432 144/18639 0.0625 2.69661458333333 0.00646188130695227 0.0894722027116468 GO:0017171 serine hydrolase activity 11/432 198/18639 0.0555555555555556 2.39699074074074 0.00662650095645102 0.0900203903517875 GO:0005003 ephrin receptor activity 5/432 53/18639 0.0943396226415094 4.07036163522013 0.00752614323739828 0.0967646987665493 GO:0005005 transmembrane-ephrin receptor activity 5/432 53/18639 0.0943396226415094 4.07036163522013 0.00752614323739828 0.0967646987665493 GO:0038064 collagen receptor activity 5/432 53/18639 0.0943396226415094 4.07036163522013 0.00752614323739828 0.0967646987665493 GO:0098641 cadherin binding involved in cell-cell adhesion 3/432 18/18639 0.166666666666667 7.19097222222222 0.00778733526662485 0.0983663402099982 GO:0016504 peptidase activator activity 5/432 57/18639 0.087719298245614 3.78472222222222 0.010188502109617 0.126477957222832 GO:0061135 endopeptidase regulator activity 10/432 184/18639 0.0543478260869565 2.34488224637681 0.0108749378227558 0.13271110563363 GO:0031406 carboxylic acid binding 10/432 187/18639 0.053475935828877 2.30726381461676 0.0120839727401018 0.145007672881222 GO:0004866 endopeptidase inhibitor activity 9/432 161/18639 0.0559006211180124 2.41187888198758 0.0129090101187586 0.150324414199549 GO:0043177 organic acid binding 10/432 189/18639 0.0529100529100529 2.28284832451499 0.01294460233385 0.150324414199549 GO:0004620 phospholipase activity 7/432 109/18639 0.0642201834862385 2.77083333333333 0.0135005856804915 0.15204469703881 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/432 22/18639 0.136363636363636 5.88352272727273 0.0137262573715593 0.15204469703881 GO:0140517 protein-RNA adaptor activity 3/432 22/18639 0.136363636363636 5.88352272727273 0.0137262573715593 0.15204469703881 GO:0004222 metalloendopeptidase activity 7/432 110/18639 0.0636363636363636 2.74564393939394 0.0141404513140504 0.15425946888055 GO:0004602 glutathione peroxidase activity 3/432 23/18639 0.130434782608696 5.62771739130435 0.0155187316720749 0.164315982410205 GO:0016493 C-C chemokine receptor activity 3/432 23/18639 0.130434782608696 5.62771739130435 0.0155187316720749 0.164315982410205 GO:0038024 cargo receptor activity 5/432 65/18639 0.0769230769230769 3.31891025641026 0.0173119697024726 0.171978182032272 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/432 89/18639 0.0674157303370786 2.90870786516854 0.0173280318280537 0.171978182032272 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/432 89/18639 0.0674157303370786 2.90870786516854 0.0173280318280537 0.171978182032272 GO:0019957 C-C chemokine binding 3/432 24/18639 0.125 5.39322916666667 0.0174366767893831 0.171978182032272 GO:0050431 transforming growth factor beta binding 3/432 24/18639 0.125 5.39322916666667 0.0174366767893831 0.171978182032272 GO:0140793 histone H2AXY142 phosphatase activity 6/432 90/18639 0.0666666666666667 2.87638888888889 0.0182153198287317 0.177230138874146 GO:0016500 protein-hormone receptor activity 5/432 67/18639 0.0746268656716418 3.21983830845771 0.0195026144555201 0.184761610631243 GO:0050840 extracellular matrix binding 5/432 67/18639 0.0746268656716418 3.21983830845771 0.0195026144555201 0.184761610631243 GO:0004955 prostaglandin receptor activity 2/432 10/18639 0.2 8.62916666666667 0.0213236218515065 0.191912596663558 GO:0005131 growth hormone receptor binding 2/432 10/18639 0.2 8.62916666666667 0.0213236218515065 0.191912596663558 GO:0019911 structural constituent of myelin sheath 2/432 10/18639 0.2 8.62916666666667 0.0213236218515065 0.191912596663558 GO:0035374 chondroitin sulfate binding 2/432 10/18639 0.2 8.62916666666667 0.0213236218515065 0.191912596663558 GO:0004252 serine-type endopeptidase activity 9/432 176/18639 0.0511363636363636 2.20632102272727 0.0217825706351257 0.193622850090006 GO:0042578 phosphoric ester hydrolase activity 15/432 363/18639 0.0413223140495868 1.78288567493113 0.0227537460187228 0.198661282089639 GO:0004867 serine-type endopeptidase inhibitor activity 6/432 95/18639 0.0631578947368421 2.725 0.0231196749874617 0.198661282089639 GO:0140359 ABC-type transporter activity 4/432 47/18639 0.0851063829787234 3.67198581560284 0.0231771495771245 0.198661282089639 GO:0019842 vitamin binding 8/432 150/18639 0.0533333333333333 2.30111111111111 0.0237938409586832 0.201547829297081 GO:0004896 cytokine receptor activity 6/432 96/18639 0.0625 2.69661458333333 0.0241970532415974 0.202579980627327 GO:0004954 prostanoid receptor activity 2/432 11/18639 0.181818181818182 7.84469696969697 0.0256675313202353 0.21161145945826 GO:0097718 disordered domain specific binding 3/432 28/18639 0.107142857142857 4.62276785714286 0.0263726043338449 0.21161145945826 GO:0004725 protein tyrosine phosphatase activity 6/432 98/18639 0.0612244897959184 2.64158163265306 0.0264514324322824 0.21161145945826 GO:0042626 ATPase-coupled transmembrane transporter activity 6/432 98/18639 0.0612244897959184 2.64158163265306 0.0264514324322824 0.21161145945826 GO:0004175 endopeptidase activity 16/432 405/18639 0.0395061728395062 1.70452674897119 0.0274884376850471 0.217490935530043 GO:0016597 amino acid binding 4/432 51/18639 0.0784313725490196 3.38398692810457 0.0302323143258277 0.236600720810826 GO:0016298 lipase activity 7/432 130/18639 0.0538461538461538 2.32323717948718 0.0318763572074733 0.246784700961084 GO:0005544 calcium-dependent phospholipid binding 4/432 53/18639 0.0754716981132075 3.2562893081761 0.0341848852645901 0.256802470461181 GO:0016860 intramolecular oxidoreductase activity 4/432 53/18639 0.0754716981132075 3.2562893081761 0.0341848852645901 0.256802470461181 GO:0005172 vascular endothelial growth factor receptor binding 2/432 13/18639 0.153846153846154 6.63782051282051 0.0353103396884124 0.256802470461181 GO:0031994 insulin-like growth factor I binding 2/432 13/18639 0.153846153846154 6.63782051282051 0.0353103396884124 0.256802470461181 GO:0070123 transforming growth factor beta receptor activity, type III 2/432 13/18639 0.153846153846154 6.63782051282051 0.0353103396884124 0.256802470461181 GO:0071837 HMG box domain binding 2/432 13/18639 0.153846153846154 6.63782051282051 0.0353103396884124 0.256802470461181 GO:0140297 DNA-binding transcription factor binding 18/432 488/18639 0.0368852459016393 1.59144467213115 0.0363206025818801 0.259842892685383 GO:0046332 SMAD binding 5/432 79/18639 0.0632911392405063 2.73074894514768 0.036450183557255 0.259842892685383 GO:0140789 histone phosphatase activity 7/432 136/18639 0.0514705882352941 2.22074142156863 0.0392393509342229 0.273539487835932 GO:0019956 chemokine binding 3/432 33/18639 0.0909090909090909 3.92234848484848 0.0403730899962216 0.273539487835932 GO:0030296 protein tyrosine kinase activator activity 3/432 33/18639 0.0909090909090909 3.92234848484848 0.0403730899962216 0.273539487835932 GO:0008559 ABC-type xenobiotic transporter activity 2/432 14/18639 0.142857142857143 6.16369047619048 0.040575295849398 0.273539487835932 GO:0044548 S100 protein binding 2/432 14/18639 0.142857142857143 6.16369047619048 0.040575295849398 0.273539487835932 GO:0030170 pyridoxal phosphate binding 4/432 56/18639 0.0714285714285714 3.08184523809524 0.0406510072200621 0.273539487835932 GO:0070279 vitamin B6 binding 4/432 57/18639 0.0701754385964912 3.02777777777778 0.0429500642095297 0.280455972768069 GO:0015035 protein-disulfide reductase activity 3/432 34/18639 0.0882352941176471 3.80698529411765 0.0435431411071427 0.280455972768069 GO:0051427 hormone receptor binding 3/432 34/18639 0.0882352941176471 3.80698529411765 0.0435431411071427 0.280455972768069 GO:0090482 vitamin transmembrane transporter activity 3/432 34/18639 0.0882352941176471 3.80698529411765 0.0435431411071427 0.280455972768069 GO:0030165 PDZ domain binding 5/432 83/18639 0.0602409638554217 2.59914658634538 0.0436264846528107 0.280455972768069 GO:1902936 phosphatidylinositol bisphosphate binding 6/432 111/18639 0.0540540540540541 2.33220720720721 0.0445077873330805 0.282438742324061 GO:0004713 protein tyrosine kinase activity 7/432 140/18639 0.05 2.15729166666667 0.0447194675346429 0.282438742324061 GO:0004953 icosanoid receptor activity 2/432 15/18639 0.133333333333333 5.75277777777778 0.046114345030143 0.286226969152612 GO:0005523 tropomyosin binding 2/432 15/18639 0.133333333333333 5.75277777777778 0.046114345030143 0.286226969152612 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/432 86/18639 0.0581395348837209 2.50847868217054 0.0495268015162136 0.301424617359268 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/432 60/18639 0.0666666666666667 2.87638888888889 0.0502777571834045 0.301424617359268 GO:0035401 histone H3Y41 kinase activity 6/432 115/18639 0.0521739130434783 2.25108695652174 0.0513029253576335 0.301424617359268 GO:0140801 histone H2AXY142 kinase activity 6/432 115/18639 0.0521739130434783 2.25108695652174 0.0513029253576335 0.301424617359268 GO:0004721 phosphoprotein phosphatase activity 8/432 175/18639 0.0457142857142857 1.97238095238095 0.0515556273114398 0.301424617359268 GO:0008081 phosphoric diester hydrolase activity 5/432 87/18639 0.0574712643678161 2.47964559386973 0.051592857526315 0.301424617359268 GO:0005024 transforming growth factor beta receptor activity 2/432 16/18639 0.125 5.39322916666667 0.0519120174340961 0.301424617359268 GO:0015378 sodium:chloride symporter activity 2/432 16/18639 0.125 5.39322916666667 0.0519120174340961 0.301424617359268 GO:0015026 coreceptor activity 4/432 61/18639 0.0655737704918033 2.8292349726776 0.0528633058160614 0.304492641500514 GO:0043394 proteoglycan binding 3/432 37/18639 0.0810810810810811 3.49831081081081 0.0537698894480684 0.307256511131819 GO:1990782 protein tyrosine kinase binding 6/432 117/18639 0.0512820512820513 2.21260683760684 0.054925491519409 0.311388613338382 GO:0000146 microfilament motor activity 3/432 38/18639 0.0789473684210526 3.40625 0.0574122071423699 0.31771278552943 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/432 17/18639 0.117647058823529 5.07598039215686 0.0579534102090586 0.31771278552943 GO:0019198 transmembrane receptor protein phosphatase activity 2/432 17/18639 0.117647058823529 5.07598039215686 0.0579534102090586 0.31771278552943 GO:0038191 neuropilin binding 2/432 17/18639 0.117647058823529 5.07598039215686 0.0579534102090586 0.31771278552943 GO:1901682 sulfur compound transmembrane transporter activity 4/432 63/18639 0.0634920634920635 2.73941798941799 0.0582473440137289 0.31771278552943 GO:0072341 modified amino acid binding 5/432 91/18639 0.0549450549450549 2.37065018315018 0.0603542676451624 0.326729869958774 GO:0030246 carbohydrate binding 11/432 280/18639 0.0392857142857143 1.69501488095238 0.0625295971920007 0.328358259405181 GO:0015108 chloride transmembrane transporter activity 6/432 121/18639 0.0495867768595041 2.13946280991736 0.0626237174386838 0.328358259405181 GO:0030695 GTPase regulator activity 17/432 489/18639 0.0347648261758691 1.49995739604635 0.064207920863797 0.328358259405181 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/432 18/18639 0.111111111111111 4.79398148148148 0.0642241695768628 0.328358259405181 GO:0015373 monoatomic anion:sodium symporter activity 2/432 18/18639 0.111111111111111 4.79398148148148 0.0642241695768628 0.328358259405181 GO:0035615 clathrin adaptor activity 2/432 18/18639 0.111111111111111 4.79398148148148 0.0642241695768628 0.328358259405181 GO:0051213 dioxygenase activity 5/432 93/18639 0.0537634408602151 2.31966845878136 0.0650327386093622 0.328358259405181 GO:0015036 disulfide oxidoreductase activity 3/432 40/18639 0.075 3.2359375 0.0650359171115189 0.328358259405181 GO:0060589 nucleoside-triphosphatase regulator activity 17/432 490/18639 0.0346938775510204 1.4968962585034 0.0651656651262287 0.328358259405181 GO:0008237 metallopeptidase activity 8/432 184/18639 0.0434782608695652 1.87590579710145 0.0652155987429735 0.328358259405181 GO:0017080 sodium channel regulator activity 3/432 41/18639 0.0731707317073171 3.15701219512195 0.0690132857919301 0.345066428959651 GO:0005520 insulin-like growth factor binding 2/432 19/18639 0.105263157894737 4.54166666666667 0.0707104734838214 0.348709184303777 GO:0097001 ceramide binding 2/432 19/18639 0.105263157894737 4.54166666666667 0.0707104734838214 0.348709184303777 GO:0140375 immune receptor activity 7/432 156/18639 0.0448717948717949 1.93603098290598 0.0714057492433065 0.349742445273338 GO:0008307 structural constituent of muscle 3/432 42/18639 0.0714285714285714 3.08184523809524 0.073098171227268 0.355612724889412 GO:0005326 neurotransmitter transmembrane transporter activity 2/432 20/18639 0.1 4.31458333333333 0.0773990147574935 0.369054904803943 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/432 20/18639 0.1 4.31458333333333 0.0773990147574935 0.369054904803943 GO:0031418 L-ascorbic acid binding 2/432 20/18639 0.1 4.31458333333333 0.0773990147574935 0.369054904803943 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/432 70/18639 0.0571428571428571 2.46547619047619 0.0792827062581132 0.373134852020913 GO:0099106 ion channel regulator activity 7/432 160/18639 0.04375 1.88763020833333 0.0792911560544441 0.373134852020913 GO:0005178 integrin binding 7/432 161/18639 0.0434782608695652 1.87590579710145 0.0813385626363667 0.376530294823608 GO:0001223 transcription coactivator binding 3/432 44/18639 0.0681818181818182 2.94176136363636 0.0815815638784484 0.376530294823608 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/432 44/18639 0.0681818181818182 2.94176136363636 0.0815815638784484 0.376530294823608 GO:0008083 growth factor activity 7/432 162/18639 0.0432098765432099 1.86432613168724 0.0834163097723768 0.38254613398797 GO:0140312 cargo adaptor activity 2/432 21/18639 0.0952380952380952 4.10912698412698 0.0842769847557026 0.384047019139911 GO:0005518 collagen binding 4/432 72/18639 0.0555555555555556 2.39699074074074 0.0859001701083121 0.388981902377262 GO:0015377 chloride:monoatomic cation symporter activity 2/432 22/18639 0.0909090909090909 3.92234848484848 0.0913320574941169 0.410994258723526 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/432 268/18639 0.0373134328358209 1.60991915422886 0.095223012661179 0.425842044199061 GO:0016247 channel regulator activity 7/432 168/18639 0.0416666666666667 1.79774305555556 0.0965161320183553 0.428960586748246 GO:0005158 insulin receptor binding 2/432 23/18639 0.0869565217391304 3.7518115942029 0.0985523742390733 0.43266896007398 GO:0005283 amino acid:sodium symporter activity 2/432 23/18639 0.0869565217391304 3.7518115942029 0.0985523742390733 0.43266896007398 GO:0008188 neuropeptide receptor activity 3/432 48/18639 0.0625 2.69661458333333 0.0997369106775342 0.434511500816019 GO:0008013 beta-catenin binding 5/432 106/18639 0.0471698113207547 2.03518081761006 0.100179040465915 0.434511500816019 GO:0141108 transporter regulator activity 7/432 170/18639 0.0411764705882353 1.7765931372549 0.101121841924008 0.435974408295125 GO:0016791 phosphatase activity 10/432 273/18639 0.0366300366300366 1.58043345543346 0.104203035181633 0.446006436011291 GO:0004622 lysophospholipase activity 2/432 24/18639 0.0833333333333333 3.59548611111111 0.105926528552682 0.446006436011291 GO:0005540 hyaluronic acid binding 2/432 24/18639 0.0833333333333333 3.59548611111111 0.105926528552682 0.446006436011291 GO:0030215 semaphorin receptor binding 2/432 24/18639 0.0833333333333333 3.59548611111111 0.105926528552682 0.446006436011291 GO:0020037 heme binding 6/432 142/18639 0.0422535211267606 1.82306338028169 0.112861209085304 0.470302923036159 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/432 25/18639 0.08 3.45166666666667 0.113443551777596 0.470302923036159 GO:0001217 DNA-binding transcription repressor activity 10/432 278/18639 0.0359712230215827 1.55200839328537 0.113656539733738 0.470302923036159 GO:0005080 protein kinase C binding 3/432 52/18639 0.0576923076923077 2.48918269230769 0.119344657922328 0.487015966950174 GO:0030159 signaling receptor complex adaptor activity 3/432 52/18639 0.0576923076923077 2.48918269230769 0.119344657922328 0.487015966950174 GO:0008198 ferrous iron binding 2/432 26/18639 0.0769230769230769 3.31891025641026 0.121092898949184 0.487015966950174 GO:0030247 polysaccharide binding 2/432 26/18639 0.0769230769230769 3.31891025641026 0.121092898949184 0.487015966950174 GO:0070006 metalloaminopeptidase activity 2/432 26/18639 0.0769230769230769 3.31891025641026 0.121092898949184 0.487015966950174 GO:0033218 amide binding 9/432 247/18639 0.0364372469635627 1.57211538461538 0.121753991737543 0.487015966950174 GO:0004864 protein phosphatase inhibitor activity 3/432 53/18639 0.0566037735849057 2.44221698113208 0.124454244281793 0.495066607087794 GO:0016853 isomerase activity 7/432 180/18639 0.0388888888888889 1.67789351851852 0.125896433518609 0.496162530955398 GO:0005254 chloride channel activity 4/432 83/18639 0.0481927710843374 2.07931726907631 0.126747288314792 0.496162530955398 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/432 181/18639 0.0386740331491713 1.66862338858195 0.128529893100258 0.496162530955398 GO:0005044 scavenger receptor activity 2/432 27/18639 0.0740740740740741 3.19598765432099 0.128864435123138 0.496162530955398 GO:0008395 steroid hydroxylase activity 2/432 27/18639 0.0740740740740741 3.19598765432099 0.128864435123138 0.496162530955398 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/432 27/18639 0.0740740740740741 3.19598765432099 0.128864435123138 0.496162530955398 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/432 54/18639 0.0555555555555556 2.39699074074074 0.129641642613476 0.496499907881399 GO:0051117 ATPase binding 4/432 84/18639 0.0476190476190476 2.05456349206349 0.130807468118588 0.498314164261286 GO:0008509 monoatomic anion transmembrane transporter activity 6/432 149/18639 0.0402684563758389 1.73741610738255 0.13311096144843 0.504420485488787 GO:0045499 chemorepellent activity 2/432 28/18639 0.0714285714285714 3.08184523809524 0.13674842210693 0.510149553974039 GO:0046625 sphingolipid binding 2/432 28/18639 0.0714285714285714 3.08184523809524 0.13674842210693 0.510149553974039 GO:0141052 histone H3 demethylase activity 2/432 28/18639 0.0714285714285714 3.08184523809524 0.13674842210693 0.510149553974039 GO:0050660 flavin adenine dinucleotide binding 4/432 86/18639 0.0465116279069767 2.00678294573643 0.139086467767176 0.514475946212023 GO:1901981 phosphatidylinositol phosphate binding 7/432 185/18639 0.0378378378378378 1.63254504504505 0.139337235432423 0.514475946212023 GO:0019212 phosphatase inhibitor activity 3/432 56/18639 0.0535714285714286 2.31138392857143 0.140239296346579 0.515164762089472 GO:0046906 tetrapyrrole binding 6/432 152/18639 0.0394736842105263 1.703125 0.142284654574314 0.515888930793658 GO:0003785 actin monomer binding 2/432 29/18639 0.0689655172413793 2.97557471264368 0.144735505583776 0.515888930793658 GO:0004629 phospholipase C activity 2/432 29/18639 0.0689655172413793 2.97557471264368 0.144735505583776 0.515888930793658 GO:0005416 amino acid:monoatomic cation symporter activity 2/432 29/18639 0.0689655172413793 2.97557471264368 0.144735505583776 0.515888930793658 GO:0043236 laminin binding 2/432 29/18639 0.0689655172413793 2.97557471264368 0.144735505583776 0.515888930793658 GO:0051861 glycolipid binding 2/432 29/18639 0.0689655172413793 2.97557471264368 0.144735505583776 0.515888930793658 GO:0005506 iron ion binding 6/432 154/18639 0.038961038961039 1.68100649350649 0.14855843754769 0.526906773568161 GO:0001965 G-protein alpha-subunit binding 2/432 30/18639 0.0666666666666667 2.87638888888889 0.152816702618134 0.528980893678156 GO:0016769 transferase activity, transferring nitrogenous groups 2/432 30/18639 0.0666666666666667 2.87638888888889 0.152816702618134 0.528980893678156 GO:0032452 histone demethylase activity 2/432 30/18639 0.0666666666666667 2.87638888888889 0.152816702618134 0.528980893678156 GO:0033612 receptor serine/threonine kinase binding 2/432 30/18639 0.0666666666666667 2.87638888888889 0.152816702618134 0.528980893678156 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/432 30/18639 0.0666666666666667 2.87638888888889 0.152816702618134 0.528980893678156 GO:0008528 G protein-coupled peptide receptor activity 5/432 122/18639 0.040983606557377 1.7682718579235 0.153845776852533 0.529531925346255 GO:0001786 phosphatidylserine binding 3/432 59/18639 0.0508474576271186 2.19385593220339 0.1566531945816 0.529531925346255 GO:0015459 potassium channel regulator activity 3/432 59/18639 0.0508474576271186 2.19385593220339 0.1566531945816 0.529531925346255 GO:0070063 RNA polymerase binding 3/432 59/18639 0.0508474576271186 2.19385593220339 0.1566531945816 0.529531925346255 GO:0070888 E-box binding 3/432 59/18639 0.0508474576271186 2.19385593220339 0.1566531945816 0.529531925346255 GO:0017147 Wnt-protein binding 2/432 31/18639 0.0645161290322581 2.78360215053763 0.160983389532007 0.536611298440023 GO:0047499 calcium-independent phospholipase A2 activity 2/432 31/18639 0.0645161290322581 2.78360215053763 0.160983389532007 0.536611298440023 GO:0140457 protein demethylase activity 2/432 31/18639 0.0645161290322581 2.78360215053763 0.160983389532007 0.536611298440023 GO:0005085 guanyl-nucleotide exchange factor activity 8/432 230/18639 0.0347826086956522 1.50072463768116 0.166564606221529 0.55265675797005 GO:0042910 xenobiotic transmembrane transporter activity 2/432 32/18639 0.0625 2.69661458333333 0.169227290141658 0.553834767736336 GO:0043425 bHLH transcription factor binding 2/432 32/18639 0.0625 2.69661458333333 0.169227290141658 0.553834767736336 GO:0047498 calcium-dependent phospholipase A2 activity 2/432 32/18639 0.0625 2.69661458333333 0.169227290141658 0.553834767736336 GO:0001653 peptide receptor activity 5/432 128/18639 0.0390625 1.68538411458333 0.176529485737964 0.575118686567122 GO:0140311 protein sequestering activity 2/432 33/18639 0.0606060606060606 2.61489898989899 0.17754046434459 0.575806911387858 GO:0005096 GTPase activator activity 9/432 271/18639 0.033210332103321 1.43288745387454 0.179369117497203 0.576622107570082 GO:0005507 copper ion binding 3/432 63/18639 0.0476190476190476 2.05456349206349 0.179393544577359 0.576622107570082 GO:0015081 sodium ion transmembrane transporter activity 6/432 164/18639 0.0365853658536585 1.57850609756098 0.181702586674575 0.580022457031762 GO:0015103 inorganic anion transmembrane transporter activity 6/432 165/18639 0.0363636363636364 1.56893939393939 0.185169439707238 0.580022457031762 GO:0019825 oxygen binding 2/432 34/18639 0.0588235294117647 2.53799019607843 0.18591529704693 0.580022457031762 GO:0015399 primary active transmembrane transporter activity 6/432 166/18639 0.036144578313253 1.55948795180723 0.18866218998568 0.580022457031762 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 11/432 349/18639 0.0315186246418338 1.35989732569245 0.188873480851457 0.580022457031762 GO:0004623 phospholipase A2 activity 2/432 35/18639 0.0571428571428571 2.46547619047619 0.194344487421644 0.580022457031762 GO:0005154 epidermal growth factor receptor binding 2/432 35/18639 0.0571428571428571 2.46547619047619 0.194344487421644 0.580022457031762 GO:0005343 organic acid:sodium symporter activity 2/432 35/18639 0.0571428571428571 2.46547619047619 0.194344487421644 0.580022457031762 GO:0044325 transmembrane transporter binding 5/432 136/18639 0.0367647058823529 1.58624387254902 0.208575210221797 0.580022457031762 GO:0030145 manganese ion binding 3/432 68/18639 0.0441176470588235 1.90349264705882 0.20896035985326 0.580022457031762 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0008239 dipeptidyl-peptidase activity 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0015643 toxic substance binding 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0016868 intramolecular phosphotransferase activity 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0031720 haptoglobin binding 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0032052 bile acid binding 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0043121 neurotrophin binding 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0043208 glycosphingolipid binding 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0043295 glutathione binding 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0050308 sugar-phosphatase activity 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0070097 delta-catenin binding 1/432 10/18639 0.1 4.31458333333333 0.209079281927956 0.580022457031762 GO:0022829 wide pore channel activity 2/432 37/18639 0.0540540540540541 2.33220720720721 0.211338247004807 0.580022457031762 GO:0015171 amino acid transmembrane transporter activity 4/432 102/18639 0.0392156862745098 1.69199346405229 0.211860391163312 0.580022457031762 GO:0005253 monoatomic anion channel activity 4/432 103/18639 0.0388349514563107 1.67556634304207 0.216729279661391 0.580022457031762 GO:0005109 frizzled binding 2/432 38/18639 0.0526315789473684 2.27083333333333 0.219889693663831 0.580022457031762 GO:0005501 retinoid binding 2/432 38/18639 0.0526315789473684 2.27083333333333 0.219889693663831 0.580022457031762 GO:0019840 isoprenoid binding 2/432 38/18639 0.0526315789473684 2.27083333333333 0.219889693663831 0.580022457031762 GO:0070851 growth factor receptor binding 5/432 139/18639 0.0359712230215827 1.55200839328537 0.221054998747382 0.580022457031762 GO:0097110 scaffold protein binding 3/432 70/18639 0.0428571428571429 1.84910714285714 0.221077608058642 0.580022457031762 GO:0042277 peptide binding 8/432 249/18639 0.0321285140562249 1.38621151271754 0.222117900130047 0.580022457031762 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0005114 type II transforming growth factor beta receptor binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0005536 D-glucose binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0008046 axon guidance receptor activity 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0008432 JUN kinase binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0010854 adenylate cyclase regulator activity 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0016594 glycine binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0019203 carbohydrate phosphatase activity 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0019215 intermediate filament binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0032794 GTPase activating protein binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0043522 leucine zipper domain binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0047676 arachidonate-CoA ligase activity 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0048407 platelet-derived growth factor binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0050998 nitric-oxide synthase binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:1900750 oligopeptide binding 1/432 11/18639 0.0909090909090909 3.92234848484848 0.227420456988728 0.580022457031762 GO:0019888 protein phosphatase regulator activity 4/432 107/18639 0.0373831775700935 1.61292834890966 0.23649515784561 0.580022457031762 GO:0004177 aminopeptidase activity 2/432 40/18639 0.05 2.15729166666667 0.237070987081215 0.580022457031762 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/432 40/18639 0.05 2.15729166666667 0.237070987081215 0.580022457031762 GO:0032451 demethylase activity 2/432 40/18639 0.05 2.15729166666667 0.237070987081215 0.580022457031762 GO:0071949 FAD binding 2/432 40/18639 0.05 2.15729166666667 0.237070987081215 0.580022457031762 GO:0019887 protein kinase regulator activity 8/432 255/18639 0.0313725490196078 1.35359477124183 0.240950862802964 0.580022457031762 GO:0004875 complement receptor activity 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0005025 transforming growth factor beta receptor activity, type I 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0005026 transforming growth factor beta receptor activity, type II 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0005078 MAP-kinase scaffold activity 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0008179 adenylate cyclase binding 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0008504 monoamine transmembrane transporter activity 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0008603 cAMP-dependent protein kinase regulator activity 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0016208 AMP binding 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0016361 activin receptor activity, type I 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0016362 activin receptor activity, type II 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0017002 activin receptor activity 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0031543 peptidyl-proline dioxygenase activity 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0045295 gamma-catenin binding 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0070008 serine-type exopeptidase activity 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0070410 co-SMAD binding 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0097677 STAT family protein binding 1/432 12/18639 0.0833333333333333 3.59548611111111 0.245337268379155 0.580022457031762 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/432 41/18639 0.0487804878048781 2.10467479674797 0.245689330737075 0.580022457031762 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/432 41/18639 0.0487804878048781 2.10467479674797 0.245689330737075 0.580022457031762 GO:0048029 monosaccharide binding 3/432 74/18639 0.0405405405405405 1.74915540540541 0.245703957492621 0.580022457031762 GO:0015293 symporter activity 5/432 146/18639 0.0342465753424658 1.47759703196347 0.250998177588916 0.590583947268038 GO:0005200 structural constituent of cytoskeleton 4/432 112/18639 0.0357142857142857 1.54092261904762 0.261763579571156 0.598874838463406 GO:0004465 lipoprotein lipase activity 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0005542 folic acid binding 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0043560 insulin receptor substrate binding 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0061459 L-arginine transmembrane transporter activity 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0070700 BMP receptor binding 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0089720 caspase binding 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0097157 pre-mRNA intronic binding 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0140333 glycerophospholipid flippase activity 1/432 13/18639 0.0769230769230769 3.31891025641026 0.262839512436717 0.598874838463406 GO:0022804 active transmembrane transporter activity 13/432 457/18639 0.0284463894967177 1.22734318016047 0.26396563775261 0.599543404359241 GO:0005543 phospholipid binding 14/432 497/18639 0.028169014084507 1.21537558685446 0.26504085784084 0.600092508318883 GO:0046943 carboxylic acid transmembrane transporter activity 6/432 188/18639 0.0319148936170213 1.37699468085106 0.27105418225127 0.601610625344278 GO:0005342 organic acid transmembrane transporter activity 6/432 189/18639 0.0317460317460317 1.36970899470899 0.275004456151892 0.601610625344278 GO:0015370 solute:sodium symporter activity 3/432 79/18639 0.0379746835443038 1.63844936708861 0.277033327937777 0.601610625344278 GO:0033293 monocarboxylic acid binding 3/432 79/18639 0.0379746835443038 1.63844936708861 0.277033327937777 0.601610625344278 GO:0001221 transcription coregulator binding 4/432 115/18639 0.0347826086956522 1.50072463768116 0.277165841429075 0.601610625344278 GO:0017124 SH3 domain binding 4/432 115/18639 0.0347826086956522 1.50072463768116 0.277165841429075 0.601610625344278 GO:0005344 oxygen carrier activity 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:0005545 1-phosphatidylinositol binding 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:0008191 metalloendopeptidase inhibitor activity 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:0015386 potassium:proton antiporter activity 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:0042043 neurexin family protein binding 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:0070742 C2H2 zinc finger domain binding 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:0098821 BMP receptor activity 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:1901474 azole transmembrane transporter activity 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:1901612 cardiolipin binding 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:1990825 sequence-specific mRNA binding 1/432 14/18639 0.0714285714285714 3.08184523809524 0.279936759866511 0.601610625344278 GO:0140303 intramembrane lipid transporter activity 2/432 45/18639 0.0444444444444444 1.91759259259259 0.280224629101902 0.601610625344278 GO:0019208 phosphatase regulator activity 4/432 117/18639 0.0341880341880342 1.47507122507123 0.287514834144457 0.601610625344278 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/432 46/18639 0.0434782608695652 1.87590579710145 0.288849948605633 0.601610625344278 GO:0030291 protein serine/threonine kinase inhibitor activity 2/432 46/18639 0.0434782608695652 1.87590579710145 0.288849948605633 0.601610625344278 GO:0015101 organic cation transmembrane transporter activity 3/432 81/18639 0.037037037037037 1.59799382716049 0.289679520603531 0.601610625344278 GO:0030971 receptor tyrosine kinase binding 3/432 81/18639 0.037037037037037 1.59799382716049 0.289679520603531 0.601610625344278 GO:0004467 long-chain fatty acid-CoA ligase activity 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0010181 FMN binding 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0015929 hexosaminidase activity 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0030553 cGMP binding 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0031005 filamin binding 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0034483 heparan sulfate sulfotransferase activity 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0050700 CARD domain binding 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0050780 dopamine receptor binding 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0140161 monocarboxylate:sodium symporter activity 1/432 15/18639 0.0666666666666667 2.87638888888889 0.296638360926251 0.601610625344278 GO:0001784 phosphotyrosine residue binding 2/432 47/18639 0.0425531914893617 1.83599290780142 0.297463031420226 0.601610625344278 GO:0005504 fatty acid binding 2/432 47/18639 0.0425531914893617 1.83599290780142 0.297463031420226 0.601610625344278 GO:0043495 protein-membrane adaptor activity 2/432 47/18639 0.0425531914893617 1.83599290780142 0.297463031420226 0.601610625344278 GO:0001540 amyloid-beta binding 3/432 83/18639 0.036144578313253 1.55948795180723 0.302366627333954 0.604092451352612 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/432 48/18639 0.0416666666666667 1.79774305555556 0.306059819278604 0.604092451352612 GO:0005126 cytokine receptor binding 8/432 275/18639 0.0290909090909091 1.25515151515152 0.307089490609378 0.604092451352612 GO:0004860 protein kinase inhibitor activity 3/432 84/18639 0.0357142857142857 1.54092261904762 0.308720670267856 0.604092451352612 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0005159 insulin-like growth factor receptor binding 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0008142 oxysterol binding 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0015385 sodium:proton antiporter activity 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0015562 efflux transmembrane transporter activity 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0016722 oxidoreductase activity, acting on metal ions 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0022841 potassium ion leak channel activity 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0030275 LRR domain binding 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0140327 flippase activity 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0140328 floppase activity 1/432 16/18639 0.0625 2.69661458333333 0.312953450492395 0.604092451352612 GO:0016763 pentosyltransferase activity 2/432 49/18639 0.0408163265306122 1.76105442176871 0.314636447738964 0.605717225593728 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0005092 GDP-dissociation inhibitor activity 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0016018 cyclosporin A binding 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0031489 myosin V binding 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0036041 long-chain fatty acid binding 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0046965 nuclear retinoid X receptor binding 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0070403 NAD+ binding 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:1990226 histone methyltransferase binding 1/432 17/18639 0.0588235294117647 2.53799019607843 0.328890953010103 0.618280642734398 GO:0004197 cysteine-type endopeptidase activity 3/432 88/18639 0.0340909090909091 1.47088068181818 0.334163594585232 0.619523606294793 GO:0031267 small GTPase binding 8/432 283/18639 0.0282685512367491 1.21967020023557 0.33460835757626 0.619523606294793 GO:0035091 phosphatidylinositol binding 8/432 284/18639 0.028169014084507 1.21537558685446 0.338077582294407 0.619523606294793 GO:0000400 four-way junction DNA binding 1/432 18/18639 0.0555555555555556 2.39699074074074 0.344459587329706 0.619523606294793 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/432 18/18639 0.0555555555555556 2.39699074074074 0.344459587329706 0.619523606294793 GO:0008525 phosphatidylcholine transporter activity 1/432 18/18639 0.0555555555555556 2.39699074074074 0.344459587329706 0.619523606294793 GO:0016854 racemase and epimerase activity 1/432 18/18639 0.0555555555555556 2.39699074074074 0.344459587329706 0.619523606294793 GO:0070628 proteasome binding 1/432 18/18639 0.0555555555555556 2.39699074074074 0.344459587329706 0.619523606294793 GO:1901611 phosphatidylglycerol binding 1/432 18/18639 0.0555555555555556 2.39699074074074 0.344459587329706 0.619523606294793 GO:0019210 kinase inhibitor activity 3/432 90/18639 0.0333333333333333 1.43819444444444 0.34687648166988 0.619523606294793 GO:0019207 kinase regulator activity 8/432 287/18639 0.0278745644599303 1.20267131242741 0.348517074621938 0.619523606294793 GO:0008146 sulfotransferase activity 2/432 53/18639 0.0377358490566038 1.62814465408805 0.34867048938102 0.619523606294793 GO:0035591 signaling adaptor activity 4/432 129/18639 0.0310077519379845 1.33785529715762 0.350432097476604 0.619523606294793 GO:0046982 protein heterodimerization activity 10/432 369/18639 0.02710027100271 1.16926377597109 0.352519236082507 0.619523606294793 GO:0003925 G protein activity 2/432 54/18639 0.037037037037037 1.59799382716049 0.357094675795156 0.619523606294793 GO:0015485 cholesterol binding 2/432 54/18639 0.037037037037037 1.59799382716049 0.357094675795156 0.619523606294793 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/432 54/18639 0.037037037037037 1.59799382716049 0.357094675795156 0.619523606294793 GO:0050661 NADP binding 2/432 54/18639 0.037037037037037 1.59799382716049 0.357094675795156 0.619523606294793 GO:0051287 NAD binding 2/432 54/18639 0.037037037037037 1.59799382716049 0.357094675795156 0.619523606294793 GO:0003756 protein disulfide isomerase activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0008301 DNA binding, bending 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0008381 mechanosensitive monoatomic ion channel activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0008574 plus-end-directed microtubule motor activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0015245 fatty acid transmembrane transporter activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0016918 retinal binding 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0022821 solute:potassium antiporter activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0022840 leak channel activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0022842 narrow pore channel activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0030506 ankyrin binding 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0042577 lipid phosphatase activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0043395 heparan sulfate proteoglycan binding 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0046624 sphingolipid transporter activity 1/432 19/18639 0.0526315789473684 2.27083333333333 0.359667871432255 0.619523606294793 GO:0003924 GTPase activity 9/432 331/18639 0.027190332326284 1.17314954682779 0.360734622139542 0.619878109643127 GO:0140313 molecular sequestering activity 2/432 55/18639 0.0363636363636364 1.56893939393939 0.365479221695762 0.625763463560299 GO:0051219 phosphoprotein binding 3/432 93/18639 0.032258064516129 1.39180107526882 0.365897802998453 0.625763463560299 GO:0170055 lipid transmembrane transporter activity 2/432 56/18639 0.0357142857142857 1.54092261904762 0.373821441153139 0.632998524585999 GO:0010851 cyclase regulator activity 1/432 20/18639 0.05 2.15729166666667 0.374524127046716 0.632998524585999 GO:0015095 magnesium ion transmembrane transporter activity 1/432 20/18639 0.05 2.15729166666667 0.374524127046716 0.632998524585999 GO:0016004 phospholipase activator activity 1/432 20/18639 0.05 2.15729166666667 0.374524127046716 0.632998524585999 GO:0016408 C-acyltransferase activity 1/432 20/18639 0.05 2.15729166666667 0.374524127046716 0.632998524585999 GO:0002020 protease binding 4/432 136/18639 0.0294117647058824 1.26899509803922 0.387298853764632 0.643922456542786 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0015174 basic amino acid transmembrane transporter activity 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0019200 carbohydrate kinase activity 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0035613 RNA stem-loop binding 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0036122 BMP binding 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0051428 peptide hormone receptor binding 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0061891 calcium ion sensor activity 1/432 21/18639 0.0476190476190476 2.05456349206349 0.389036484161266 0.643922456542786 GO:0016922 nuclear receptor binding 4/432 137/18639 0.0291970802919708 1.25973236009732 0.392549666344972 0.648247155432064 GO:0005319 lipid transporter activity 5/432 178/18639 0.0280898876404494 1.21196161048689 0.396049977726717 0.65092663118927 GO:0045309 protein phosphorylated amino acid binding 2/432 59/18639 0.0338983050847458 1.46257062146893 0.398569427979211 0.65092663118927 GO:0030295 protein kinase activator activity 4/432 139/18639 0.0287769784172662 1.2416067146283 0.403030556636929 0.65092663118927 GO:0005243 gap junction channel activity 1/432 22/18639 0.0454545454545455 1.96117424242424 0.403212885431131 0.65092663118927 GO:0008093 cytoskeletal anchor activity 1/432 22/18639 0.0454545454545455 1.96117424242424 0.403212885431131 0.65092663118927 GO:0008970 phospholipase A1 activity 1/432 22/18639 0.0454545454545455 1.96117424242424 0.403212885431131 0.65092663118927 GO:0031683 G-protein beta/gamma-subunit complex binding 1/432 22/18639 0.0454545454545455 1.96117424242424 0.403212885431131 0.65092663118927 GO:0033691 sialic acid binding 1/432 22/18639 0.0454545454545455 1.96117424242424 0.403212885431131 0.65092663118927 GO:0061133 endopeptidase activator activity 1/432 22/18639 0.0454545454545455 1.96117424242424 0.403212885431131 0.65092663118927 GO:0140784 metal ion sensor activity 1/432 22/18639 0.0454545454545455 1.96117424242424 0.403212885431131 0.65092663118927 GO:0031681 G-protein beta-subunit binding 1/432 23/18639 0.0434782608695652 1.87590579710145 0.417061090485315 0.662878554413746 GO:0043274 phospholipase binding 1/432 23/18639 0.0434782608695652 1.87590579710145 0.417061090485315 0.662878554413746 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/432 23/18639 0.0434782608695652 1.87590579710145 0.417061090485315 0.662878554413746 GO:0070577 lysine-acetylated histone binding 1/432 23/18639 0.0434782608695652 1.87590579710145 0.417061090485315 0.662878554413746 GO:0099186 structural constituent of postsynapse 1/432 23/18639 0.0434782608695652 1.87590579710145 0.417061090485315 0.662878554413746 GO:0140103 catalytic activity, acting on a glycoprotein 1/432 23/18639 0.0434782608695652 1.87590579710145 0.417061090485315 0.662878554413746 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/432 23/18639 0.0434782608695652 1.87590579710145 0.417061090485315 0.662878554413746 GO:0008238 exopeptidase activity 3/432 102/18639 0.0294117647058824 1.26899509803922 0.422244041720155 0.663862633183904 GO:0019903 protein phosphatase binding 4/432 144/18639 0.0277777777777778 1.19849537037037 0.429073382384729 0.663862633183904 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0004806 triacylglycerol lipase activity 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0035035 histone acetyltransferase binding 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0050699 WW domain binding 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0060229 lipase activator activity 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0140033 acetylation-dependent protein binding 1/432 24/18639 0.0416666666666667 1.79774305555556 0.43058868013456 0.663862633183904 GO:0141003 histone H2AX kinase activity 9/432 354/18639 0.0254237288135593 1.0969279661017 0.436578213969566 0.667002548072534 GO:0008234 cysteine-type peptidase activity 5/432 187/18639 0.0267379679144385 1.15363190730838 0.437208826036362 0.667002548072534 GO:0008483 transaminase activity 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0015271 outward rectifier potassium channel activity 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0015645 fatty acid ligase activity 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0015662 P-type ion transporter activity 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0042974 nuclear retinoic acid receptor binding 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0120515 fatty acid-CoA ligase activity 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0140358 P-type transmembrane transporter activity 1/432 25/18639 0.04 1.72583333333333 0.443803060482767 0.667002548072534 GO:0140996 histone H3 kinase activity 9/432 357/18639 0.0252100840336134 1.08771008403361 0.44645950507967 0.667002548072534 GO:0004497 monooxygenase activity 3/432 106/18639 0.0283018867924528 1.22110849056604 0.446760925371215 0.667002548072534 GO:0051020 GTPase binding 8/432 315/18639 0.0253968253968254 1.0957671957672 0.446886444991031 0.667002548072534 GO:0019209 kinase activator activity 4/432 148/18639 0.027027027027027 1.1661036036036 0.449692501022377 0.667002548072534 GO:0008235 metalloexopeptidase activity 2/432 66/18639 0.0303030303030303 1.3074494949495 0.454422090842373 0.667002548072534 GO:0035173 histone kinase activity 9/432 360/18639 0.025 1.07864583333333 0.456318728717438 0.667002548072534 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0004435 phosphatidylinositol phospholipase C activity 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0005112 Notch binding 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0005160 transforming growth factor beta receptor binding 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0008157 protein phosphatase 1 binding 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0043548 phosphatidylinositol 3-kinase binding 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0050681 nuclear androgen receptor binding 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0051139 metal cation:proton antiporter activity 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0070412 R-SMAD binding 1/432 26/18639 0.0384615384615385 1.65945512820513 0.45671146694411 0.667002548072534 GO:0004364 glutathione transferase activity 1/432 27/18639 0.037037037037037 1.59799382716049 0.469320968167994 0.677914071620109 GO:0016405 CoA-ligase activity 1/432 27/18639 0.037037037037037 1.59799382716049 0.469320968167994 0.677914071620109 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/432 27/18639 0.037037037037037 1.59799382716049 0.469320968167994 0.677914071620109 GO:0035255 ionotropic glutamate receptor binding 1/432 27/18639 0.037037037037037 1.59799382716049 0.469320968167994 0.677914071620109 GO:0005548 phospholipid transporter activity 2/432 68/18639 0.0294117647058824 1.26899509803922 0.469832113525603 0.677914071620109 GO:0032934 sterol binding 2/432 68/18639 0.0294117647058824 1.26899509803922 0.469832113525603 0.677914071620109 GO:0003774 cytoskeletal motor activity 4/432 153/18639 0.0261437908496732 1.12799564270153 0.475122804308229 0.68417683820385 GO:0016866 intramolecular transferase activity 1/432 28/18639 0.0357142857142857 1.54092261904762 0.481638469873959 0.686692471899506 GO:0046875 ephrin receptor binding 1/432 28/18639 0.0357142857142857 1.54092261904762 0.481638469873959 0.686692471899506 GO:0050698 proteoglycan sulfotransferase activity 1/432 28/18639 0.0357142857142857 1.54092261904762 0.481638469873959 0.686692471899506 GO:0051393 alpha-actinin binding 1/432 28/18639 0.0357142857142857 1.54092261904762 0.481638469873959 0.686692471899506 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/432 28/18639 0.0357142857142857 1.54092261904762 0.481638469873959 0.686692471899506 GO:0016782 transferase activity, transferring sulphur-containing groups 2/432 70/18639 0.0285714285714286 1.2327380952381 0.484979063461677 0.690088785953374 GO:0140299 molecular sensor activity 2/432 71/18639 0.028169014084507 1.21537558685446 0.49245124672419 0.698316144186637 GO:0035250 UDP-galactosyltransferase activity 1/432 29/18639 0.0344827586206897 1.48778735632184 0.493670718598609 0.698316144186637 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/432 29/18639 0.0344827586206897 1.48778735632184 0.493670718598609 0.698316144186637 GO:0015291 secondary active transmembrane transporter activity 7/432 287/18639 0.024390243902439 1.05233739837398 0.499194559525881 0.704745260507126 GO:0098918 structural constituent of synapse 1/432 30/18639 0.0333333333333333 1.43819444444444 0.505424305356556 0.711659007878387 GO:0015294 solute:monoatomic cation symporter activity 3/432 116/18639 0.0258620689655172 1.11584051724138 0.506068627824631 0.711659007878387 GO:0016878 acid-thiol ligase activity 1/432 31/18639 0.032258064516129 1.39180107526882 0.516905669217374 0.725481641006841 GO:0019003 GDP binding 2/432 75/18639 0.0266666666666667 1.15055555555556 0.521644354159962 0.730708044737691 GO:0005516 calmodulin binding 5/432 207/18639 0.0241545893719807 1.04216988727858 0.525821023294114 0.73354698360526 GO:0008378 galactosyltransferase activity 1/432 32/18639 0.03125 1.34830729166667 0.528121100800462 0.73354698360526 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/432 32/18639 0.03125 1.34830729166667 0.528121100800462 0.73354698360526 GO:0051059 NF-kappaB binding 1/432 32/18639 0.03125 1.34830729166667 0.528121100800462 0.73354698360526 GO:0017022 myosin binding 2/432 76/18639 0.0263157894736842 1.13541666666667 0.528765117348792 0.73354698360526 GO:0042923 neuropeptide binding 1/432 33/18639 0.0303030303030303 1.3074494949495 0.539076745689708 0.743554131985804 GO:0071889 14-3-3 protein binding 1/432 33/18639 0.0303030303030303 1.3074494949495 0.539076745689708 0.743554131985804 GO:0140416 transcription regulator inhibitor activity 1/432 33/18639 0.0303030303030303 1.3074494949495 0.539076745689708 0.743554131985804 GO:0003713 transcription coactivator activity 6/432 256/18639 0.0234375 1.01123046875 0.546372628859951 0.750859055248021 GO:0008376 acetylgalactosaminyltransferase activity 1/432 34/18639 0.0294117647058824 1.26899509803922 0.549778607769792 0.750859055248021 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/432 34/18639 0.0294117647058824 1.26899509803922 0.549778607769792 0.750859055248021 GO:0031625 ubiquitin protein ligase binding 7/432 302/18639 0.0231788079470199 1.00006898454746 0.5531693363827 0.750859055248021 GO:0000049 tRNA binding 2/432 80/18639 0.025 1.07864583333333 0.55652158855807 0.750859055248021 GO:0016229 steroid dehydrogenase activity 1/432 35/18639 0.0285714285714286 1.2327380952381 0.560232552485914 0.750859055248021 GO:0140566 histone reader activity 1/432 35/18639 0.0285714285714286 1.2327380952381 0.560232552485914 0.750859055248021 GO:0001618 virus receptor activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0033192 calmodulin-dependent protein phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0140791 histone H2AXS140 phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/432 81/18639 0.0246913580246914 1.065329218107 0.563277083949324 0.750859055248021 GO:0042826 histone deacetylase binding 3/432 127/18639 0.0236220472440945 1.01919291338583 0.567287536073442 0.750859055248021 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/432 82/18639 0.024390243902439 1.05233739837398 0.569958537538521 0.750859055248021 GO:0033549 MAP kinase phosphatase activity 2/432 82/18639 0.024390243902439 1.05233739837398 0.569958537538521 0.750859055248021 GO:0140272 exogenous protein binding 2/432 82/18639 0.024390243902439 1.05233739837398 0.569958537538521 0.750859055248021 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/432 36/18639 0.0277777777777778 1.19849537037037 0.570444310028705 0.750859055248021 GO:0016409 palmitoyltransferase activity 1/432 36/18639 0.0277777777777778 1.19849537037037 0.570444310028705 0.750859055248021 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/432 36/18639 0.0277777777777778 1.19849537037037 0.570444310028705 0.750859055248021 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/432 36/18639 0.0277777777777778 1.19849537037037 0.570444310028705 0.750859055248021 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/432 36/18639 0.0277777777777778 1.19849537037037 0.570444310028705 0.750859055248021 GO:0031490 chromatin DNA binding 3/432 128/18639 0.0234375 1.01123046875 0.572618580925261 0.750975188098703 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/432 128/18639 0.0234375 1.01123046875 0.572618580925261 0.750975188098703 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/432 83/18639 0.0240963855421687 1.03965863453815 0.576565745197893 0.754776975531787 GO:0030280 structural constituent of skin epidermis 1/432 37/18639 0.027027027027027 1.1661036036036 0.580419478446036 0.755111087673624 GO:0030551 cyclic nucleotide binding 1/432 37/18639 0.027027027027027 1.1661036036036 0.580419478446036 0.755111087673624 GO:0042805 actinin binding 1/432 37/18639 0.027027027027027 1.1661036036036 0.580419478446036 0.755111087673624 GO:0017018 myosin phosphatase activity 2/432 84/18639 0.0238095238095238 1.02728174603175 0.583098551903504 0.755111087673624 GO:0019001 guanyl nucleotide binding 9/432 400/18639 0.0225 0.97078125 0.583113562147966 0.755111087673624 GO:0032561 guanyl ribonucleotide binding 9/432 400/18639 0.0225 0.97078125 0.583113562147966 0.755111087673624 GO:0016757 glycosyltransferase activity 6/432 267/18639 0.0224719101123595 0.969569288389513 0.587562655156405 0.75950648422372 GO:0042887 amide transmembrane transporter activity 1/432 38/18639 0.0263157894736842 1.13541666666667 0.590163526683392 0.760139068357858 GO:0043531 ADP binding 1/432 38/18639 0.0263157894736842 1.13541666666667 0.590163526683392 0.760139068357858 GO:0008514 organic anion transmembrane transporter activity 6/432 269/18639 0.0223048327137546 0.962360594795539 0.594843143754726 0.764798327684648 GO:0003712 transcription coregulator activity 11/432 495/18639 0.0222222222222222 0.958796296296296 0.599386448444928 0.766911002201089 GO:0000217 DNA secondary structure binding 1/432 39/18639 0.0256410256410256 1.10630341880342 0.599681797554463 0.766911002201089 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/432 39/18639 0.0256410256410256 1.10630341880342 0.599681797554463 0.766911002201089 GO:0030331 nuclear estrogen receptor binding 1/432 40/18639 0.025 1.07864583333333 0.60897951064352 0.774673582444054 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/432 40/18639 0.025 1.07864583333333 0.60897951064352 0.774673582444054 GO:0140662 ATP-dependent protein folding chaperone 1/432 40/18639 0.025 1.07864583333333 0.60897951064352 0.774673582444054 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/432 41/18639 0.024390243902439 1.05233739837398 0.618061765141182 0.780955277997986 GO:0140828 metal cation:monoatomic cation antiporter activity 1/432 41/18639 0.024390243902439 1.05233739837398 0.618061765141182 0.780955277997986 GO:0000287 magnesium ion binding 5/432 230/18639 0.0217391304347826 0.937952898550725 0.619391940812213 0.780955277997986 GO:0008017 microtubule binding 6/432 276/18639 0.0217391304347826 0.937952898550725 0.619779409272307 0.780955277997986 GO:0044389 ubiquitin-like protein ligase binding 7/432 322/18639 0.0217391304347826 0.937952898550725 0.620891583612486 0.780955277997986 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/432 91/18639 0.021978021978022 0.948260073260073 0.626741298739868 0.780955277997986 GO:0016859 cis-trans isomerase activity 1/432 42/18639 0.0238095238095238 1.02728174603175 0.62693354261505 0.780955277997986 GO:0019894 kinesin binding 1/432 42/18639 0.0238095238095238 1.02728174603175 0.62693354261505 0.780955277997986 GO:0035198 miRNA binding 1/432 42/18639 0.0238095238095238 1.02728174603175 0.62693354261505 0.780955277997986 GO:0042056 chemoattractant activity 1/432 42/18639 0.0238095238095238 1.02728174603175 0.62693354261505 0.780955277997986 GO:0043175 RNA polymerase core enzyme binding 1/432 42/18639 0.0238095238095238 1.02728174603175 0.62693354261505 0.780955277997986 GO:0048487 beta-tubulin binding 1/432 42/18639 0.0238095238095238 1.02728174603175 0.62693354261505 0.780955277997986 GO:0043178 alcohol binding 2/432 92/18639 0.0217391304347826 0.937952898550725 0.632678530591121 0.783616080472705 GO:0052689 carboxylic ester hydrolase activity 2/432 92/18639 0.0217391304347826 0.937952898550725 0.632678530591121 0.783616080472705 GO:0005245 voltage-gated calcium channel activity 1/432 43/18639 0.0232558139534884 1.00339147286822 0.635599709716749 0.783616080472705 GO:0008200 ion channel inhibitor activity 1/432 43/18639 0.0232558139534884 1.00339147286822 0.635599709716749 0.783616080472705 GO:0008375 acetylglucosaminyltransferase activity 1/432 43/18639 0.0232558139534884 1.00339147286822 0.635599709716749 0.783616080472705 GO:0048156 tau protein binding 1/432 43/18639 0.0232558139534884 1.00339147286822 0.635599709716749 0.783616080472705 GO:0001046 core promoter sequence-specific DNA binding 1/432 44/18639 0.0227272727272727 0.980587121212121 0.644065020826792 0.788651045910358 GO:0016248 channel inhibitor activity 1/432 44/18639 0.0227272727272727 0.980587121212121 0.644065020826792 0.788651045910358 GO:0030547 signaling receptor inhibitor activity 1/432 44/18639 0.0227272727272727 0.980587121212121 0.644065020826792 0.788651045910358 GO:0043014 alpha-tubulin binding 1/432 44/18639 0.0227272727272727 0.980587121212121 0.644065020826792 0.788651045910358 GO:0019902 phosphatase binding 4/432 190/18639 0.0210526315789474 0.908333333333333 0.645303266160295 0.788825724338561 GO:0005525 GTP binding 8/432 378/18639 0.0211640211640212 0.913139329805996 0.652144124151538 0.792041428094232 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/432 45/18639 0.0222222222222222 0.958796296296296 0.652334120638722 0.792041428094232 GO:0042605 peptide antigen binding 1/432 45/18639 0.0222222222222222 0.958796296296296 0.652334120638722 0.792041428094232 GO:0141110 transporter inhibitor activity 1/432 45/18639 0.0222222222222222 0.958796296296296 0.652334120638722 0.792041428094232 GO:0008194 UDP-glycosyltransferase activity 3/432 145/18639 0.0206896551724138 0.892672413793103 0.656778813432459 0.796095531433283 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/432 46/18639 0.0217391304347826 0.937952898550725 0.660411546683901 0.79781260673223 GO:0030276 clathrin binding 1/432 46/18639 0.0217391304347826 0.937952898550725 0.660411546683901 0.79781260673223 GO:0016758 hexosyltransferase activity 4/432 197/18639 0.0203045685279188 0.876057529610829 0.673097903646868 0.809144196696063 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/432 48/18639 0.0208333333333333 0.898871527777778 0.676009006532791 0.809144196696063 GO:0032266 phosphatidylinositol-3-phosphate binding 1/432 48/18639 0.0208333333333333 0.898871527777778 0.676009006532791 0.809144196696063 GO:0038187 pattern recognition receptor activity 1/432 48/18639 0.0208333333333333 0.898871527777778 0.676009006532791 0.809144196696063 GO:0140693 molecular condensate scaffold activity 1/432 48/18639 0.0208333333333333 0.898871527777778 0.676009006532791 0.809144196696063 GO:0004674 protein serine/threonine kinase activity 9/432 433/18639 0.0207852193995381 0.896795612009238 0.676534453348653 0.809144196696063 GO:0035254 glutamate receptor binding 1/432 49/18639 0.0204081632653061 0.880527210884354 0.683537601507663 0.816164300307657 GO:0001664 G protein-coupled receptor binding 6/432 297/18639 0.0202020202020202 0.871632996632997 0.689089643979808 0.821431363684539 GO:0004722 protein serine/threonine phosphatase activity 2/432 103/18639 0.0194174757281553 0.837783171521036 0.693173021572201 0.824933182697495 GO:0003743 translation initiation factor activity 1/432 51/18639 0.0196078431372549 0.845996732026144 0.698075188759489 0.826667986688869 GO:0005272 sodium channel activity 1/432 51/18639 0.0196078431372549 0.845996732026144 0.698075188759489 0.826667986688869 GO:0030544 Hsp70 protein binding 1/432 51/18639 0.0196078431372549 0.845996732026144 0.698075188759489 0.826667986688869 GO:0003714 transcription corepressor activity 4/432 204/18639 0.0196078431372549 0.845996732026144 0.699354905321094 0.826823533384544 GO:0005246 calcium channel regulator activity 1/432 53/18639 0.0188679245283019 0.814072327044025 0.711946426024029 0.837584030616505 GO:0017046 peptide hormone binding 1/432 53/18639 0.0188679245283019 0.814072327044025 0.711946426024029 0.837584030616505 GO:0051018 protein kinase A binding 1/432 53/18639 0.0188679245283019 0.814072327044025 0.711946426024029 0.837584030616505 GO:0004843 cysteine-type deubiquitinase activity 2/432 108/18639 0.0185185185185185 0.798996913580247 0.717837528830229 0.840865131206303 GO:0005496 steroid binding 2/432 108/18639 0.0185185185185185 0.798996913580247 0.717837528830229 0.840865131206303 GO:0140463 chromatin-protein adaptor activity 1/432 54/18639 0.0185185185185185 0.798996913580247 0.718641742066083 0.840865131206303 GO:0046873 metal ion transmembrane transporter activity 9/432 450/18639 0.02 0.862916666666667 0.719406834476504 0.840865131206303 GO:0015079 potassium ion transmembrane transporter activity 3/432 160/18639 0.01875 0.808984375 0.720585482251829 0.840877710245246 GO:0008374 O-acyltransferase activity 1/432 55/18639 0.0181818181818182 0.784469696969697 0.725181788739608 0.844871986881096 GO:0003730 mRNA 3'-UTR binding 5/432 262/18639 0.0190839694656489 0.823393765903308 0.729603110435378 0.848649821508032 GO:0061980 regulatory RNA binding 1/432 58/18639 0.0172413793103448 0.743893678160919 0.74390582627774 0.863890636967698 GO:0101005 deubiquitinase activity 2/432 115/18639 0.0173913043478261 0.75036231884058 0.749549296650084 0.866611764878877 GO:0004879 nuclear receptor activity 1/432 59/18639 0.0169491525423729 0.731285310734463 0.749859902110473 0.866611764878877 GO:0036002 pre-mRNA binding 1/432 59/18639 0.0169491525423729 0.731285310734463 0.749859902110473 0.866611764878877 GO:0009055 electron transfer activity 2/432 116/18639 0.0172413793103448 0.743893678160919 0.753820887331232 0.869793331536037 GO:0098531 ligand-modulated transcription factor activity 1/432 60/18639 0.0166666666666667 0.719097222222222 0.755675861329433 0.870538592251506 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/432 61/18639 0.0163934426229508 0.707308743169399 0.761356900562206 0.875226074387991 GO:0022853 active monoatomic ion transmembrane transporter activity 2/432 118/18639 0.0169491525423729 0.731285310734463 0.762176039779542 0.875226074387991 GO:0015179 L-amino acid transmembrane transporter activity 1/432 62/18639 0.0161290322580645 0.695900537634409 0.7669061426204 0.879255450138038 GO:0051082 unfolded protein binding 2/432 121/18639 0.0165289256198347 0.713154269972452 0.77424795670495 0.8862615720629 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/432 122/18639 0.0163934426229508 0.707308743169399 0.778151547984 0.887906679157655 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/432 122/18639 0.0163934426229508 0.707308743169399 0.778151547984 0.887906679157655 GO:0019843 rRNA binding 1/432 65/18639 0.0153846153846154 0.663782051282051 0.782793242065123 0.891789769441279 GO:0015631 tubulin binding 7/432 385/18639 0.0181818181818182 0.784469696969697 0.792170508343381 0.900317683093107 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/432 67/18639 0.0149253731343284 0.643967661691542 0.792779737612541 0.900317683093107 GO:0005125 cytokine activity 4/432 234/18639 0.0170940170940171 0.737535612535613 0.794585444746957 0.900947275933558 GO:0019783 ubiquitin-like protein peptidase activity 2/432 127/18639 0.015748031496063 0.679461942257218 0.796795215833587 0.901525734711956 GO:0003777 microtubule motor activity 1/432 68/18639 0.0147058823529412 0.634497549019608 0.797599851404884 0.901525734711956 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/432 130/18639 0.0153846153846154 0.663782051282051 0.807305065074595 0.909639509943205 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/432 130/18639 0.0153846153846154 0.663782051282051 0.807305065074595 0.909639509943205 GO:0005262 calcium channel activity 2/432 131/18639 0.0152671755725191 0.658715012722646 0.810699484074824 0.910614085076246 GO:0031072 heat shock protein binding 2/432 131/18639 0.0152671755725191 0.658715012722646 0.810699484074824 0.910614085076246 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/432 132/18639 0.0151515151515152 0.653724747474748 0.814040544146929 0.912942666333004 GO:0005216 monoatomic ion channel activity 8/432 448/18639 0.0178571428571429 0.77046130952381 0.818779002110667 0.915979711416202 GO:0043539 protein serine/threonine kinase activator activity 1/432 73/18639 0.0136986301369863 0.591038812785388 0.820073343140433 0.915979711416202 GO:0051087 protein-folding chaperone binding 2/432 134/18639 0.0149253731343284 0.643967661691542 0.820565158143681 0.915979711416202 GO:0015297 antiporter activity 2/432 135/18639 0.0148148148148148 0.639197530864198 0.823749994420547 0.918111448889774 GO:0044183 protein folding chaperone 1/432 75/18639 0.0133333333333333 0.575277777777778 0.82834933754146 0.921810700200697 GO:0004679 AMP-activated protein kinase activity 4/432 248/18639 0.0161290322580645 0.695900537634409 0.829930394128437 0.92214488236493 GO:0140767 enzyme-substrate adaptor activity 2/432 139/18639 0.0143884892086331 0.620803357314149 0.83598774982755 0.926302714201438 GO:0003724 RNA helicase activity 1/432 77/18639 0.012987012987013 0.560335497835498 0.836245505876298 0.926302714201438 GO:0008186 ATP-dependent activity, acting on RNA 1/432 79/18639 0.0126582278481013 0.546149789029536 0.843779241642078 0.933212064488934 GO:0022843 voltage-gated monoatomic cation channel activity 2/432 143/18639 0.013986013986014 0.603438228438228 0.847453272209634 0.935837969311253 GO:0016887 ATP hydrolysis activity 7/432 417/18639 0.0167865707434053 0.724270583533173 0.85329834146389 0.940849626116387 GO:0008135 translation factor activity, RNA binding 1/432 83/18639 0.0120481927710843 0.519829317269076 0.857825051994439 0.943349892075432 GO:0015085 calcium ion transmembrane transporter activity 2/432 147/18639 0.0136054421768707 0.587018140589569 0.858186360151955 0.943349892075432 GO:0180051 translation factor activity 1/432 84/18639 0.0119047619047619 0.513640873015873 0.86113500982686 0.945148181517285 GO:0003727 single-stranded RNA binding 1/432 89/18639 0.0112359550561798 0.484784644194757 0.876566556085784 0.960620883381681 GO:0042562 hormone binding 1/432 94/18639 0.0106382978723404 0.458998226950355 0.890286777833684 0.971347023576914 GO:0005249 voltage-gated potassium channel activity 1/432 98/18639 0.0102040816326531 0.440263605442177 0.900158794477842 0.971347023576914 GO:0016874 ligase activity 2/432 167/18639 0.0119760479041916 0.516716566866267 0.902186213993379 0.971347023576914 GO:0005244 voltage-gated monoatomic ion channel activity 2/432 173/18639 0.0115606936416185 0.498795761078998 0.912672768868685 0.971347023576914 GO:0061630 ubiquitin protein ligase activity 5/432 353/18639 0.0141643059490085 0.611130783758262 0.914887878926946 0.971347023576914 GO:0003735 structural constituent of ribosome 2/432 175/18639 0.0114285714285714 0.493095238095238 0.915927790843679 0.971347023576914 GO:0022832 voltage-gated channel activity 2/432 175/18639 0.0114285714285714 0.493095238095238 0.915927790843679 0.971347023576914 GO:0000149 SNARE binding 1/432 106/18639 0.00943396226415094 0.407036163522013 0.917323004722957 0.971347023576914 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/432 243/18639 0.0123456790123457 0.532664609053498 0.923173933516206 0.971347023576914 GO:0106310 protein serine kinase activity 5/432 361/18639 0.0138504155124654 0.597587719298246 0.923928667516795 0.971347023576914 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0004711 ribosomal protein S6 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0035175 histone H3S10 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0035979 histone H2AXS139 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0044022 histone H3S28 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0044023 histone H4S1 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0044024 histone H2AS1 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0044025 histone H2BS14 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0072354 histone H3T3 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0072371 histone H2AS121 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0140823 histone H2BS36 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0140855 histone H3S57 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0140995 histone H2A kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0140997 histone H4 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0140998 histone H2B kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:1990244 histone H2AT120 kinase activity 3/432 245/18639 0.0122448979591837 0.528316326530612 0.925713507680567 0.971347023576914 GO:0004677 DNA-dependent protein kinase activity 3/432 246/18639 0.0121951219512195 0.526168699186992 0.926954279629769 0.971347023576914 GO:0140857 histone H3T45 kinase activity 3/432 246/18639 0.0121951219512195 0.526168699186992 0.926954279629769 0.971347023576914 GO:0035402 histone H3T11 kinase activity 3/432 247/18639 0.0121457489878543 0.524038461538462 0.928176044751273 0.971347023576914 GO:0035403 histone H3T6 kinase activity 3/432 247/18639 0.0121457489878543 0.524038461538462 0.928176044751273 0.971347023576914 GO:0015078 proton transmembrane transporter activity 2/432 185/18639 0.0108108108108108 0.466441441441442 0.930562587484633 0.972431150927338 GO:0061659 ubiquitin-like protein ligase activity 5/432 372/18639 0.0134408602150538 0.57991711469534 0.934969394647363 0.9756202378929 GO:0005267 potassium channel activity 1/432 124/18639 0.00806451612903226 0.347950268817204 0.945934250279152 0.985633372215614 GO:0045182 translation regulator activity 4/432 356/18639 0.0112359550561798 0.484784644194757 0.966941963934322 0.999882545309067 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/432 229/18639 0.00873362445414847 0.376819505094614 0.970735822585392 0.999882545309067 GO:0000510 H3-H4 histone complex chaperone activity 1/432 151/18639 0.00662251655629139 0.285733995584989 0.971431461083567 0.999882545309067 GO:0140584 chromatin extrusion motor activity 1/432 151/18639 0.00662251655629139 0.285733995584989 0.971431461083567 0.999882545309067 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/432 151/18639 0.00662251655629139 0.285733995584989 0.971431461083567 0.999882545309067 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/432 151/18639 0.00662251655629139 0.285733995584989 0.971431461083567 0.999882545309067 GO:0015616 DNA translocase activity 1/432 152/18639 0.00657894736842105 0.283854166666667 0.972099008076854 0.999882545309067 GO:0140674 ATP-dependent histone chaperone activity 1/432 152/18639 0.00657894736842105 0.283854166666667 0.972099008076854 0.999882545309067 GO:0061775 cohesin loader activity 1/432 153/18639 0.0065359477124183 0.281998910675381 0.972750992093233 0.999882545309067 GO:0004386 helicase activity 1/432 155/18639 0.00645161290322581 0.278360215053763 0.974009710825821 0.999882545309067 GO:0140658 ATP-dependent chromatin remodeler activity 1/432 158/18639 0.00632911392405063 0.273074894514768 0.975789847803834 0.999882545309067 GO:0003689 DNA clamp loader activity 1/432 160/18639 0.00625 0.269661458333333 0.976908491078207 0.999882545309067 GO:0140713 histone chaperone activity 1/432 164/18639 0.00609756097560976 0.263084349593496 0.978993429859649 0.999882545309067 GO:0004842 ubiquitin-protein transferase activity 5/432 449/18639 0.0111358574610245 0.48046585003712 0.979750770011827 0.999882545309067 GO:0140104 molecular carrier activity 2/432 249/18639 0.00803212851405622 0.346552878179384 0.980440384705835 0.999882545309067 GO:0140030 modification-dependent protein binding 1/432 173/18639 0.00578034682080925 0.249397880539499 0.983023287304726 0.999896049014101 GO:0003823 antigen binding 1/432 174/18639 0.00574712643678161 0.247964559386973 0.98342044640168 0.999896049014101 GO:0005261 monoatomic cation channel activity 3/432 341/18639 0.00879765395894428 0.37958211143695 0.986549164051025 0.999896049014101 GO:0019787 ubiquitin-like protein transferase activity 5/432 479/18639 0.0104384133611691 0.450374043145442 0.987506868777356 0.999896049014101 GO:0140597 protein carrier chaperone 1/432 188/18639 0.00531914893617021 0.229499113475177 0.988099014551534 0.999896049014101 GO:0016755 aminoacyltransferase activity 5/432 496/18639 0.0100806451612903 0.434937836021505 0.990555811375409 0.999896049014101 GO:0016829 lyase activity 1/432 200/18639 0.005 0.215729166666667 0.991044806358299 0.999896049014101 GO:0008094 ATP-dependent activity, acting on DNA 1/432 210/18639 0.00476190476190476 0.205456349206349 0.992935367945839 0.999896049014101 GO:0016741 transferase activity, transferring one-carbon groups 1/432 215/18639 0.00465116279069767 0.200678294573643 0.993725550576674 0.999896049014101 GO:0022836 gated channel activity 2/432 318/18639 0.00628930817610063 0.271357442348008 0.995304351039964 0.999896049014101 GO:0042393 histone binding 1/432 247/18639 0.00404858299595142 0.174679487179487 0.997065385025099 0.999896049014101 GO:0030371 translation repressor activity 1/432 329/18639 0.00303951367781155 0.131142350557244 0.999583894089875 0.999896049014101 GO:0140097 catalytic activity, acting on DNA 1/432 336/18639 0.00297619047619048 0.128410218253968 0.999647948688972 0.999896049014101 GO:0140098 catalytic activity, acting on RNA 1/432 387/18639 0.00258397932816537 0.111487941429802 0.999896049014101 0.999896049014101