category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	20/102	233/9376	7.89026340149794	VIM/COL3A1/FBLN1/COL1A1/COL6A3/COL1A2/COL4A2/VCAN/COL6A1/COL6A2/ACTG1/COL4A1/FBLN2/FN1/ITGB1/TPM4/LAMA2/COL5A1/MYL9/PDLIM1	11.1691880602661
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	17/102	203/9376	7.69786535303777	COL1A1/COL6A3/COL1A2/COL4A2/COL6A1/COL6A2/ACTG1/COL4A1/PAK3/FN1/ITGB1/FYN/JUN/LAMA2/CAV1/MYL9/IGF1	10.1176793868036
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	10/102	89/9376	10.3282661379158	COL1A1/COL6A3/COL1A2/COL4A2/COL6A1/COL6A2/COL4A1/FN1/ITGB1/LAMA2	9.27278919953762
NA	NA	hsa04518	Integrin signaling	12/102	154/9376	7.16271963330787	COL1A1/COL6A3/COL1A2/COL4A2/COL6A1/COL6A2/ACTG1/COL4A1/FN1/ITGB1/LAMA2/IGF1	8.08671970395966
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	10/102	101/9376	9.10114540865851	COL3A1/COL1A1/COL1A2/COL4A2/FOXO1/COL4A1/FN1/JUN/STAT3/EGR1	8.58424953276122
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	10/102	103/9376	8.92442413858747	COL3A1/COL1A1/COL6A3/COL1A2/COL4A2/COL6A1/COL6A2/COL15A1/COL4A1/COL5A1	8.48063502075418
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	12/102	204/9376	5.40715109573241	COL1A1/COL1A2/TIMP3/ACTG1/DDX5/FN1/ITGB1/STAT3/CAV1/TWIST2/IGF1/PDCD4	6.67410721771099
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	14/102	362/9376	3.55497779222186	COL1A1/COL6A3/COL1A2/COL4A2/COL6A1/COL6A2/COL4A1/FN1/FGF10/ITGB1/LAMA2/IGF1/DDIT4/INSR	5.19917955680417
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	11/102	238/9376	4.24847586093261	CFD/C1R/RPL12/RPS2/RPL3/C1S/RPL5/NRP1/RPL10A/JUN/STAT3	5.32346893248118
Organismal Systems	Immune system	hsa04611	Platelet activation	8/102	126/9376	5.83629007158419	COL3A1/COL1A1/COL1A2/ACTG1/PRKG1/ITGB1/FYN/GUCY1A2	5.73164027390985
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/102	205/9376	4.48397895743663	COL3A1/COL1A1/MT-CO3/COL1A2/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/INSR/MT-ND3	5.28927668007491
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	7/102	103/9376	6.24709689701123	COL3A1/COL1A1/COL1A2/COL4A2/COL4A1/FN1/LAMA2	5.61538768292328
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	6/102	99/9376	5.57100415923945	ACTG1/ITGB1/CACNB2/TPM4/LAMA2/IGF1	4.79487857659743
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	8/102	184/9376	3.99658994032396	SEMA5A/CXCL12/PAK3/NRP1/ITGB1/FYN/TRPC4/MYL9	4.30510154038055
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	9/102	232/9376	3.56592292089249	TMSB4X/CXCL12/ACTG1/PAK3/FN1/FGF10/ITGB1/MYL9/GSN	4.15022524967798
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	11/102	333/9376	3.0364482129188	COL1A1/COL6A3/COL1A2/COL4A2/COL6A1/COL6A2/FOXO1/COL4A1/FN1/ITGB1/LAMA2	3.96818033030596
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	6/102	105/9376	5.25266106442577	ACTG1/ITGB1/CACNB2/TPM4/LAMA2/IGF1	4.59562208957179
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/102	87/9376	5.28284877169259	MT-CO3/MT-CO1/MT-CYB/CACNB2/TPM4	4.20881719225608
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/102	130/9376	4.24253393665158	COL3A1/COL1A1/COL1A2/COL4A2/COL4A1/JUN	3.90419445270454
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	9/102	275/9376	3.00834224598931	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/FYN/CAV1/EGR1/MT-ND3	3.5449628793721
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	5/102	93/9376	4.94201981868016	COL4A2/COL4A1/FN1/ITGB1/LAMA2	4.00652890906156
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	6/102	138/9376	3.99658994032396	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3	3.71903323803202
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	8/102	235/9376	3.12924488944514	MT-CO3/MT-CO1/ACTG1/MT-ND5/PRKG1/MT-CYB/MT-ATP8/MT-ND3	3.46668888883807
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	6/102	154/9376	3.58135981665393	ACTG1/EEF2/CACNB2/JUN/MYL9/GUCY1A2	3.38725993302091
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	4/102	70/9376	5.25266106442577	ACTG1/FYN/LAMA2/CAV1	3.74524683075504
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	4/102	78/9376	4.71392659627954	ACTG1/FN1/ITGB1/CAV1	3.45412479788417
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	4/102	78/9376	4.71392659627954	C1R/C1S/ITGB1/JUN	3.45412479788417
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	7/102	227/9376	2.83458581670554	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/JUN/MT-ND3	2.93437980250388
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	6/102	178/9376	3.09847984137475	SFRP2/APCDD1/MCC/JUN/SERPINF1/PRICKLE2	2.96428719820422
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	4/102	86/9376	4.27542179662563	ACTG1/ITGB1/CACNB2/LAMA2	3.20007960310139
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/102	134/9376	3.42990927714369	PRKG1/RAMP1/CALD1/MYL9/GUCY1A2	2.97106158801955
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	4/102	88/9376	4.17825311942959	CFD/C1R/C1S/PROCR	3.14138302721755
NA	NA	hsa04517	IgSF CAM signaling	8/102	299/9376	2.45943996327628	FOXO1/ACTG1/PAK3/NLGN1/NRP1/ITGB1/FYN/MYL9	2.68969378174843
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	4/102	93/9376	3.95361585494413	ACTG1/FYN/MYL9/INSR	3.00195023196466
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	6/102	201/9376	2.74392742171495	ZEB1/FOXO1/PBX1/DDX5/MEIS1/IGF1	2.6210516379942
Organismal Systems	Nervous system	hsa04730	Long-term depression	3/102	60/9376	4.59607843137255	PRKG1/IGF1/GUCY1A2	2.93050332716958
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	5/102	157/9376	2.9274384913201	MT-CO3/MT-CO1/MT-CYB/JUN/INSR	2.55411604127244
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	3/102	62/9376	4.44781783681214	FOXO1/IGF1/INSR	2.85643416131754
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/102	66/9376	4.17825311942959	RORA/JUN/STAT3	2.71730124331483
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	4/102	116/9376	3.16970926301555	CXCL12/ACTG1/ITGB1/MYL9	2.4659100049123
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	4/102	122/9376	3.01382192221151	FOXO1/EEF2/IGF1/INSR	2.34794765353325
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	7/102	308/9376	2.0891265597148	TGM2/MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3	2.03821564017804
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	2/102	34/9376	5.40715109573241	RORA/RORB	2.69978789368269
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/102	133/9376	2.76455845496093	FOXO1/STAT3/IGF1/INSR	2.14935213031412
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	8/102	388/9376	1.8952900747928	MT-CO3/APOE/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/INSR/MT-ND3	1.88886221554882
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	7/102	323/9376	1.99210829842773	VIM/ZEB1/TIMP3/MARCKS/STAT3/DDIT4/PDCD4	1.90290129450449
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/102	138/9376	2.6643932935493	ACTG1/FN1/ITGB1/JUN	2.06565933382205
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	2/102	38/9376	4.83797729618163	IGF1/INSR	2.48610486325596
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/102	200/9376	2.29803921568627	ACTG1/PAK3/ITGB1/FYN/JUN	1.94593480991676
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	6/102	268/9376	2.05794556628622	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3	1.84277107683102
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/102	90/9376	3.0640522875817	FOXO1/IGF1/INSR	2.06338271539546
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/102	212/9376	2.16796152423233	ACTG1/FGF10/ITGB1/IGF1/INSR	1.80387360856801
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/102	95/9376	2.90278637770898	CXCL12/IL15/JUN	1.95481934508618
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/102	155/9376	2.37216951296648	ACTG1/C1R/ITGB1/CALR	1.80649507651178
NA	NA	hsa04081	Hormone signaling	5/102	219/9376	2.09866595039842	PRKG1/RAMP1/STAT3/IGF1/INSR	1.72529472226389
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	3/102	98/9376	2.81392557022809	MARCKS/PLPP1/GSN	1.89302999320199
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/102	99/9376	2.78550207961973	CFD/C1R/C1S	1.87295075038025
Genetic Information Processing	Translation	hsa03010	Ribosome	5/102	222/9376	2.07030559971736	RPL12/RPS2/RPL3/RPL5/RPL10A	1.69250908708926
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/102	224/9376	2.05182072829132	NRP1/IL15/JUN/EGR1/CALR	1.67093635034043
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/102	227/9376	2.02470415478967	CXCL12/AKAP13/STAT3/CCL4L2/CALR	1.63899183563744
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/102	50/9376	3.67686274509804	CXCL12/IL15	1.99028641383428
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/102	368/9376	1.74850809889173	MT-CO3/MT-CO1/ACTG1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3	1.53623764332114
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	4/102	166/9376	2.21497755728798	PRKG1/MYL9/GUCY1A2/INSR	1.65632159070249
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/102	106/9376	2.6015538290788	ZEB1/FOXO1/IGF1	1.73902883834602
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/102	52/9376	3.53544494720965	IGF1/INSR	1.92267953070872
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	4/102	170/9376	2.16286043829296	ACTG1/ITGB1/JUN/MYL9	1.6046072471166
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/102	109/9376	2.52995143011333	RORA/JUN/STAT3	1.68489751464165
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	3/102	109/9376	2.52995143011333	FOXO1/STAT3/INSR	1.68489751464165
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/102	110/9376	2.50695187165775	STAT3/IGF1/INSR	1.66725395067587
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/102	112/9376	2.46218487394958	ITGB1/STAT3/LAMA2	1.63254139951924
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/102	59/9376	3.11598537720173	PRKG1/INSR	1.70982947137621
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/102	253/9376	1.81663179105634	FOXO1/ACTG1/ITGB1/JUN/MYL9	1.38092433915045
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/102	122/9376	2.26036644165863	PAK3/FYN/JUN	1.46948168387931
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/102	122/9376	2.26036644165863	FOXO1/ACTG1/MED13L	1.46948168387931
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/102	65/9376	2.82835595776772	PBX1/PDE8B	1.55121303164609
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/102	70/9376	2.62633053221289	PAK3/JUN	1.43228185346883
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/102	205/9376	1.79359158297465	VIM/JUN/STAT3/CALR	1.20480792353004
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/102	73/9376	2.51839914047811	FGF10/IGF1	1.36580295222548
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	3/102	142/9376	1.94200497100249	ACTG1/JUN/CAV1	1.1861909601032
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	3/102	144/9376	1.91503267973856	MEIS1/STAT3/IGF1	1.16043850613585
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/102	78/9376	2.35696329813977	BTG1/PABPC1	1.26203909970074
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/102	78/9376	2.35696329813977	ITGB1/JUN	1.26203909970074
NA	NA	hsa04382	Cornified envelope formation	4/102	217/9376	1.69440679497606	S100A6/COL4A2/S100A4/COL4A1	1.08535541563081
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	2/102	80/9376	2.29803921568627	STAT3/IGF1	1.22274790562441
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/102	148/9376	1.86327503974563	FGF10/JUN/IGF1	1.1101417279979
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/102	149/9376	1.8507698381366	PLPP1/FYN/INSR	1.09780988482421
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	5/102	300/9376	1.53202614379085	FGF10/CACNB2/JUN/IGF1/INSR	0.982196848083047
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	2/102	83/9376	2.21497755728798	AUTS2/SFMBT2	1.16595425525557
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/102	86/9376	2.13771089831281	PAK3/JUN	1.111540945251
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/102	158/9376	1.74534623976173	IGF1/DDIT4/INSR	0.990878567231525
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/102	89/9376	2.06565322758317	PRKG1/GUCY1A2	1.0593155891019
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/102	160/9376	1.72352941176471	VCAN/NLGN1/ITGB1	0.968048522954245
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/102	90/9376	2.04270152505447	JUN/STAT3	1.04236327590064
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/102	238/9376	1.5449003130664	PAK3/FGF10/IGF1/INSR	0.892960271859765
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/102	91/9376	2.02025425554837	CD81/JUN	1.0256291019621
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/102	93/9376	1.97680792747206	JUN/EGR1	0.992792877770882
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/102	93/9376	1.97680792747206	PRKG1/GUCY1A2	0.992792877770882
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	4/102	248/9376	1.48260594560405	ACTG1/PAK3/JUN/MYL9	0.807760981637665
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/102	97/9376	1.8952900747928	PRKG1/GUCY1A2	0.929503924986529
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/102	31/9376	2.9652118912081	PCCA	1.14935120552944
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/102	99/9376	1.85700138641315	JUN/IGF1	0.898974808307858
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/102	99/9376	1.85700138641315	PLPP1/JUN	0.898974808307858
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/102	174/9376	1.58485463150778	PDIA6/DNAJA1/CALR	0.816645590542376
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/102	32/9376	2.87254901960784	PCCA	1.11274063546937
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/102	100/9376	1.83843137254902	CXCL12/CCL4L2	0.883973668833634
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/102	103/9376	1.78488482771749	JUN/CALR	0.839975453205119
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/102	105/9376	1.75088702147526	CXCL12/CCL4L2	0.811443218819136
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/102	109/9376	1.68663428674222	JUN/CCL4L2	0.756173287876213
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/102	193/9376	1.42883267296556	CXCL12/STAT3/CCL4L2	0.631286362800444
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/102	194/9376	1.4214675560946	ACTG1/TPM4/MYL9	0.622083307526119
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/102	115/9376	1.59863597612958	AKAP13/EGR1	0.677384054775284
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/102	119/9376	1.5449003130664	IL15/JUN	0.627346651923705
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/102	43/9376	2.13771089831281	PLPP1	0.784165428161155
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/102	122/9376	1.50691096110575	STAT3/IGF1	0.591015714225368
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/102	205/9376	1.34519368723099	JUN/STAT3/GSN	0.524063130772556
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/102	47/9376	1.95577805590321	INSR	0.688875304316203
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/102	128/9376	1.43627450980392	PDE8B/GUCY1A2	0.521186420680347
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/102	48/9376	1.91503267973856	PCCA	0.666522988864428
NA	NA	hsa03272	Virion - Hepatitis viruses	1/102	48/9376	1.91503267973856	CD81	0.666522988864428
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/102	214/9376	1.28862012094557	PAK3/JUN/CALR	0.447909759719995
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/102	49/9376	1.87595038015206	JUN	0.644701581213205
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/102	217/9376	1.27080509623204	FGF10/JUN/STAT3	0.423267427540081
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/102	50/9376	1.83843137254902	CD81	0.623385929208569
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	6/102	480/9376	1.14901960784314	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3	0.351494736534611
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/102	51/9376	1.80238369857747	PLPP1	0.602552569778301
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/102	51/9376	1.80238369857747	ACTG1	0.602552569778301
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/102	52/9376	1.76772247360483	APOE	0.582179584253861
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/102	136/9376	1.3517877739331	JUN/STAT3	0.433377528724378
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/102	137/9376	1.3419207098898	ACTG1/JUN	0.422790660207561
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/102	138/9376	1.33219664677465	FOXO1/INSR	0.412285429612085
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/102	54/9376	1.70225127087872	REV3L	0.542734016980503
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/102	55/9376	1.67130124777184	PLPP1	0.523624216441166
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/102	142/9376	1.29466998066832	FYN/JUN	0.371054164300824
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/102	143/9376	1.28561634443987	C1R/C1S	0.360937358490165
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/102	149/9376	1.23384655875773	MT-ND5/MT-ND3	0.301749136169005
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/102	63/9376	1.45907251789605	PTGDS	0.383406036507734
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/102	154/9376	1.19378660555131	CACNB2/TPM4	0.254286752395079
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/102	155/9376	1.18608475648324	PBX1/PDE8B	0.244985180930102
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/102	156/9376	1.17848164906988	CD81/STAT3	0.235745052372609
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/102	65/9376	1.41417797888386	PLPP1	0.351396715467757
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/102	65/9376	1.41417797888386	TRPC4	0.351396715467757
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/102	157/9376	1.17097539652804	PBX1/CALR	0.226565467537224
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/102	68/9376	1.3517877739331	STAT3	0.305322766773964
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/102	69/9376	1.33219664677465	FYN	0.290447144450677
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/102	69/9376	1.33219664677465	GUCY1A2	0.290447144450677
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/102	69/9376	1.33219664677465	JUN	0.290447144450677
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/102	163/9376	1.12787200769879	JUN/STAT3	0.172711369919015
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/102	70/9376	1.31316526610644	STAT3	0.275799364825724
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/102	71/9376	1.29466998066832	STAT3	0.261371998474993
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/102	71/9376	1.29466998066832	JUN	0.261371998474993
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/102	168/9376	1.09430438842204	IL15/STAT3	0.129346912559723
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/102	73/9376	1.25919957023905	MAP1B	0.233150512806932
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/102	73/9376	1.25919957023905	STAT3	0.233150512806932
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/102	75/9376	1.22562091503268	REV3L	0.205729866388993
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/102	75/9376	1.22562091503268	IGF1	0.205729866388993
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/102	76/9376	1.20949432404541	ACTG1	0.192304639042822
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/102	76/9376	1.20949432404541	IGF1	0.192304639042822
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/102	77/9376	1.19378660555131	STAT3	0.179061893450129
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/102	78/9376	1.17848164906988	INPP4B	0.165996250609027
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	2/102	180/9376	1.02135076252723	PILRA/CALR	0.0303320902635782
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/102	82/9376	1.12099473935916	CALR	0.115404902596457
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/102	83/9376	1.10748877864399	CCL4L2	0.103151698646954
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/102	87/9376	1.05656975433852	JUN	0.0555919126062345
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/102	89/9376	1.03282661379158	PLCL1	0.0326313877974329
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/102	91/9376	1.01012712777419	PDE8B	0.0101804789423905
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/102	196/9376	0.93797519007603	JUN/STAT3	-0.0920289178816745
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/102	298/9376	0.925384919068298	CXCL12/IL15/CCL4L2	-0.1372751211048
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/102	93/9376	0.988403963736032	JUN	-0.0117857993260087
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/102	94/9376	0.977889027951606	JUN	-0.0225945220317092
NA	NA	hsa04519	Cadherin signaling	4/102	404/9376	0.910114540865851	VIM/ACTG1/LHFPL6/PRICKLE2	-0.193681290226713
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/102	98/9376	0.93797519007603	INPP4B	-0.0647296820971341
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/102	99/9376	0.928500693206576	IGF1	-0.0750011337645336
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/102	103/9376	0.892442413858747	PABPC1	-0.115106992738514
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/102	104/9376	0.883861236802413	PLPP1	-0.124899106988808
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/102	105/9376	0.875443510737628	JUN	-0.134601498869028
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/102	105/9376	0.875443510737628	JUN	-0.134601498869028
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/102	216/9376	0.851125635439361	JUN/STAT3	-0.232140672288894
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/102	107/9376	0.859080080630383	FOXO1	-0.15374464997649
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/102	110/9376	0.835650623885918	THSD4	-0.181832049032784
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/102	110/9376	0.835650623885918	IGF1	-0.181832049032784
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/102	226/9376	0.813465209092487	JUN/MYL9	-0.297684139017922
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/102	115/9376	0.799317988064791	FYN	-0.227080897883939
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/102	116/9376	0.792427315753888	PCCA	-0.235909744938634
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/102	117/9376	0.785654432713256	ACTG1	-0.244668226385693
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/102	120/9376	0.766013071895425	JUN	-0.270534542147361
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/102	125/9376	0.735372549019608	FYN	-0.312354478947804
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/102	133/9376	0.691139613740233	FYN	-0.376212942853044
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/102	138/9376	0.666098323387326	IGF1	-0.4144015224929
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/102	139/9376	0.661306249118352	JUN	-0.421892000038787
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/102	140/9376	0.656582633053221	EGR1	-0.429335191647276
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/102	144/9376	0.638344226579521	FOXO1	-0.458649504806076
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/102	144/9376	0.638344226579521	RORA	-0.458649504806076
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/102	150/9376	0.61281045751634	FGF10	-0.501319619909829
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/102	157/9376	0.585487698264019	FOXO1	-0.549284723707849
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/102	157/9376	0.585487698264019	ACTG1	-0.549284723707849
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/102	168/9376	0.547152194211018	STAT3	-0.62112131278679
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/102	169/9376	0.543914607263024	DDIT4	-0.627455054508858
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/102	170/9376	0.540715109573241	ACTG1	-0.633757791908184
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/102	173/9376	0.531338546979485	ACTG1	-0.652483830229961
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/102	187/9376	0.491559190521128	JUN	-0.736511033492282
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/102	195/9376	0.471392659627954	ACTG1	-0.782271809246498
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/102	243/9376	0.378278060195272	DDX5	-1.02978077481196
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/102	250/9376	0.367686274509804	CAV1	-1.06270949151259
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/102	254/9376	0.361895939478153	FGF10	-1.08122358595177
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/102	449/9376	0.204725097165815	PRKG1	-1.81108927471217