ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 21/164 168/18639 0.125 14.2065548780488 1.74836623430424e-18 7.86764805436908e-16 GO:0019838 growth factor binding 16/164 136/18639 0.117647058823529 13.37087517934 6.46812497094702e-14 1.45532811846308e-11 GO:0030020 extracellular matrix structural constituent conferring tensile strength 10/164 44/18639 0.227272727272727 25.8300997782705 4.0460940778404e-12 6.0691411167606e-10 GO:0048407 platelet-derived growth factor binding 6/164 11/18639 0.545454545454545 61.9922394678492 1.88585512377474e-10 2.12158701424658e-08 GO:0005520 insulin-like growth factor binding 6/164 19/18639 0.315789473684211 35.890243902439 1.04478430749325e-08 9.40305876743925e-07 GO:0005178 integrin binding 12/164 161/18639 0.0745341614906832 8.47098924405393 1.92920039042471e-08 1.44690029281854e-06 GO:0005539 glycosaminoglycan binding 14/164 242/18639 0.0578512396694215 6.57493448901431 3.12189797329929e-08 2.00693441140669e-06 GO:0031994 insulin-like growth factor I binding 5/164 13/18639 0.384615384615385 43.7124765478424 6.03130820407362e-08 3.39261086479141e-06 GO:0001968 fibronectin binding 6/164 30/18639 0.2 22.730487804878 2.11050214841602e-07 1.05525107420801e-05 GO:0008201 heparin binding 11/164 172/18639 0.063953488372093 7.26846993760635 3.63742111476343e-07 1.63683950164354e-05 GO:1901681 sulfur compound binding 13/164 275/18639 0.0472727272727273 5.37266075388027 9.96791768595247e-07 4.07778450788965e-05 GO:0050840 extracellular matrix binding 7/164 67/18639 0.104477611940299 11.8741354204587 2.00449710511826e-06 7.51686414419347e-05 GO:0005518 collagen binding 7/164 72/18639 0.0972222222222222 11.0495426829268 3.27267569947071e-06 0.000113284928058602 GO:0043236 laminin binding 4/164 29/18639 0.137931034482759 15.6761984861228 0.000115582520860162 0.00362932707508551 GO:0140313 molecular sequestering activity 5/164 55/18639 0.0909090909090909 10.3320399113082 0.000120977569169517 0.00362932707508551 GO:0016504 peptidase activator activity 5/164 57/18639 0.087719298245614 9.96951219512195 0.000143564957940831 0.00403776444208588 GO:0061134 peptidase regulator activity 9/164 226/18639 0.0398230088495575 4.52598208504209 0.000179943502924407 0.00476321037152842 GO:0043394 proteoglycan binding 4/164 37/18639 0.108108108108108 12.2867501647989 0.000304280896769872 0.0076070224192468 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 5/164 68/18639 0.0735294117647059 8.35679698708752 0.000330683097558921 0.0078319681000797 GO:0003779 actin binding 11/164 443/18639 0.0248306997742664 2.82206959202775 0.00191603828231125 0.043110861352003 GO:0015026 coreceptor activity 4/164 61/18639 0.0655737704918033 7.45261895241903 0.00204155173843765 0.0437475372522354 GO:0032934 sterol binding 4/164 68/18639 0.0588235294117647 6.68543758967001 0.00303817309142617 0.0621444495973536 GO:0009055 electron transfer activity 5/164 116/18639 0.0431034482758621 4.89881202691337 0.00363109349177359 0.0710431335347006 GO:0022853 active monoatomic ion transmembrane transporter activity 5/164 118/18639 0.0423728813559322 4.81578131459281 0.00390601768777171 0.0723088513231832 GO:0097493 structural molecule activity conferring elasticity 2/164 11/18639 0.181818181818182 20.6640798226164 0.00401715840684351 0.0723088513231832 GO:0046332 SMAD binding 4/164 79/18639 0.0506329113924051 5.75455387465267 0.00520312778762173 0.0900541347857608 GO:0048306 calcium-dependent protein binding 4/164 80/18639 0.05 5.68262195121951 0.00544009589524721 0.0906682649207868 GO:0015078 proton transmembrane transporter activity 6/164 185/18639 0.0324324324324324 3.68602504943968 0.00596853944857383 0.0959229554235081 GO:0002020 protease binding 5/164 136/18639 0.0367647058823529 4.17839849354376 0.0070867955476941 0.108786244457285 GO:0004129 cytochrome-c oxidase activity 2/164 15/18639 0.133333333333333 15.1536585365854 0.00749416350705739 0.108786244457285 GO:0005523 tropomyosin binding 2/164 15/18639 0.133333333333333 15.1536585365854 0.00749416350705739 0.108786244457285 GO:0005159 insulin-like growth factor receptor binding 2/164 16/18639 0.125 14.2065548780488 0.00851557414900632 0.112706128442731 GO:0008142 oxysterol binding 2/164 16/18639 0.125 14.2065548780488 0.00851557414900632 0.112706128442731 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/164 16/18639 0.125 14.2065548780488 0.00851557414900632 0.112706128442731 GO:0043178 alcohol binding 4/164 92/18639 0.0434782608695652 4.94141039236479 0.00886380792104108 0.1139632446991 GO:0098641 cadherin binding involved in cell-cell adhesion 2/164 18/18639 0.111111111111111 12.6280487804878 0.0107331473882709 0.134164342353386 GO:0004857 enzyme inhibitor activity 9/164 416/18639 0.0216346153846154 2.45882680581613 0.0115101098633818 0.134431618013906 GO:0043395 heparan sulfate proteoglycan binding 2/164 19/18639 0.105263157894737 11.9634146341463 0.0119271293002126 0.134431618013906 GO:0015485 cholesterol binding 3/164 54/18639 0.0555555555555556 6.3140243902439 0.0119494771567917 0.134431618013906 GO:0140463 chromatin-protein adaptor activity 3/164 54/18639 0.0555555555555556 6.3140243902439 0.0119494771567917 0.134431618013906 GO:0008083 growth factor activity 5/164 162/18639 0.0308641975308642 3.50779132791328 0.0143590020647747 0.157598803149966 GO:0004879 nuclear receptor activity 3/164 59/18639 0.0508474576271186 5.77893757751137 0.0151713223281384 0.158687244391337 GO:0005496 steroid binding 4/164 108/18639 0.037037037037037 4.20934959349593 0.015268444353044 0.158687244391337 GO:0015399 primary active transmembrane transporter activity 5/164 166/18639 0.0301204819277108 3.4232662356744 0.0158022997443489 0.158687244391337 GO:0098531 ligand-modulated transcription factor activity 3/164 60/18639 0.05 5.68262195121951 0.0158687244391337 0.158687244391337 GO:0003735 structural constituent of ribosome 5/164 175/18639 0.0285714285714286 3.24721254355401 0.019396263762959 0.18756717094639 GO:0038024 cargo receptor activity 3/164 65/18639 0.0461538461538462 5.24549718574109 0.0196233882888006 0.18756717094639 GO:0008143 poly(A) binding 2/164 26/18639 0.0769230769230769 8.74249530956848 0.0217772123481248 0.18756717094639 GO:0043548 phosphatidylinositol 3-kinase binding 2/164 26/18639 0.0769230769230769 8.74249530956848 0.0217772123481248 0.18756717094639 GO:0050681 nuclear androgen receptor binding 2/164 26/18639 0.0769230769230769 8.74249530956848 0.0217772123481248 0.18756717094639 GO:0050750 low-density lipoprotein particle receptor binding 2/164 26/18639 0.0769230769230769 8.74249530956848 0.0217772123481248 0.18756717094639 GO:0070412 R-SMAD binding 2/164 26/18639 0.0769230769230769 8.74249530956848 0.0217772123481248 0.18756717094639 GO:1990841 promoter-specific chromatin binding 3/164 68/18639 0.0441176470588235 5.01407819225251 0.0220912445781304 0.18756717094639 GO:0008266 poly(U) RNA binding 2/164 27/18639 0.0740740740740741 8.41869918699187 0.0233853846472763 0.191461243757387 GO:0061135 endopeptidase regulator activity 5/164 184/18639 0.0271739130434783 3.088381495228 0.0234901548561623 0.191461243757387 GO:0097110 scaffold protein binding 3/164 70/18639 0.0428571428571429 4.87081881533101 0.0238262881120304 0.191461243757387 GO:0008187 poly-pyrimidine tract binding 2/164 30/18639 0.0666666666666667 7.57682926829268 0.0284900296879028 0.219787564235298 GO:0045296 cadherin binding 7/164 334/18639 0.0209580838323353 2.38193734482255 0.028590990812242 0.219787564235298 GO:0017022 myosin binding 3/164 76/18639 0.0394736842105263 4.48628048780488 0.0294618701040067 0.219787564235298 GO:0098631 cell adhesion mediator activity 3/164 76/18639 0.0394736842105263 4.48628048780488 0.0294618701040067 0.219787564235298 GO:0017147 Wnt-protein binding 2/164 31/18639 0.0645161290322581 7.3324154209284 0.0302818421835299 0.219787564235298 GO:0070325 lipoprotein particle receptor binding 2/164 31/18639 0.0645161290322581 7.3324154209284 0.0302818421835299 0.219787564235298 GO:0070717 poly-purine tract binding 2/164 32/18639 0.0625 7.10327743902439 0.0321172623829504 0.229409017021075 GO:0140311 protein sequestering activity 2/164 33/18639 0.0606060606060606 6.8880266075388 0.0339953943008827 0.239030116178082 GO:0001540 amyloid-beta binding 3/164 83/18639 0.036144578313253 4.10791948280929 0.0368468389419 0.25142586003381 GO:0020037 heme binding 4/164 142/18639 0.028169014084507 3.20147715561663 0.0368757928049587 0.25142586003381 GO:0019955 cytokine binding 4/164 144/18639 0.0277777777777778 3.15701219512195 0.0385072224109175 0.258630598282282 GO:0046906 tetrapyrrole binding 4/164 152/18639 0.0263157894736842 2.99085365853659 0.0454415263484091 0.300715983188001 GO:0042562 hormone binding 3/164 94/18639 0.0319148936170213 3.62720550077841 0.0501748329605923 0.31191340498892 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/164 41/18639 0.0487804878048781 5.54402141582391 0.0504545205624565 0.31191340498892 GO:0042287 MHC protein binding 2/164 41/18639 0.0487804878048781 5.54402141582391 0.0504545205624565 0.31191340498892 GO:0031625 ubiquitin protein ligase binding 6/164 302/18639 0.0198675496688742 2.25799547730577 0.0510829788013916 0.31191340498892 GO:0004867 serine-type endopeptidase inhibitor activity 3/164 95/18639 0.0315789473684211 3.5890243902439 0.05148823295407 0.31191340498892 GO:0008307 structural constituent of muscle 2/164 42/18639 0.0476190476190476 5.41202090592335 0.0526787083981287 0.31191340498892 GO:0035198 miRNA binding 2/164 42/18639 0.0476190476190476 5.41202090592335 0.0526787083981287 0.31191340498892 GO:0042056 chemoattractant activity 2/164 42/18639 0.0476190476190476 5.41202090592335 0.0526787083981287 0.31191340498892 GO:0004866 endopeptidase inhibitor activity 4/164 161/18639 0.0248447204968944 2.82366308135131 0.0540224863966055 0.315715829590552 GO:0048156 tau protein binding 2/164 43/18639 0.0465116279069767 5.2861599546228 0.0549372970710014 0.316945944640393 GO:0003954 NADH dehydrogenase activity 2/164 44/18639 0.0454545454545455 5.1660199556541 0.0572295173828665 0.321916035278624 GO:0030547 signaling receptor inhibitor activity 2/164 44/18639 0.0454545454545455 5.1660199556541 0.0572295173828665 0.321916035278624 GO:0030414 peptidase inhibitor activity 4/164 169/18639 0.0236686390532544 2.6899985567903 0.0623369588253959 0.346316437918866 GO:0044389 ubiquitin-like protein ligase binding 6/164 322/18639 0.0186335403726708 2.11774731101348 0.065500207428774 0.354611139565432 GO:0032266 phosphatidylinositol-3-phosphate binding 2/164 48/18639 0.0416666666666667 4.73551829268293 0.06671970377044 0.354611139565432 GO:0008013 beta-catenin binding 3/164 106/18639 0.0283018867924528 3.21657846295444 0.0670096134750831 0.354611139565432 GO:0033218 amide binding 5/164 247/18639 0.0202429149797571 2.30065666041276 0.067496158689162 0.354611139565432 GO:0019888 protein phosphatase regulator activity 3/164 107/18639 0.0280373831775701 3.18651698199225 0.068515608204424 0.354611139565432 GO:0001222 transcription corepressor binding 2/164 49/18639 0.0408163265306122 4.63887506222001 0.069168915256072 0.354611139565432 GO:0042277 peptide binding 5/164 249/18639 0.0200803212851406 2.2821774904496 0.0693495129930048 0.354611139565432 GO:0004252 serine-type endopeptidase activity 4/164 176/18639 0.0227272727272727 2.58300997782705 0.0701342031584966 0.354611139565432 GO:0005021 vascular endothelial growth factor receptor activity 2/164 51/18639 0.0392156862745098 4.45695839311334 0.0741543532899336 0.36901007707051 GO:0005200 structural constituent of cytoskeleton 3/164 112/18639 0.0267857142857143 3.04426175958188 0.0762735474803955 0.36901007707051 GO:0004864 protein phosphatase inhibitor activity 2/164 53/18639 0.0377358490566038 4.28877128393925 0.079251215621327 0.36901007707051 GO:0016860 intramolecular oxidoreductase activity 2/164 53/18639 0.0377358490566038 4.28877128393925 0.079251215621327 0.36901007707051 GO:0017046 peptide hormone binding 2/164 53/18639 0.0377358490566038 4.28877128393925 0.079251215621327 0.36901007707051 GO:0019208 phosphatase regulator activity 3/164 117/18639 0.0256410256410256 2.91416510318949 0.0844004787785739 0.36901007707051 GO:0098632 cell-cell adhesion mediator activity 2/164 55/18639 0.0363636363636364 4.13281596452328 0.0844541234157738 0.36901007707051 GO:0005522 profilin binding 1/164 10/18639 0.1 11.365243902439 0.0846038602773245 0.36901007707051 GO:0015279 store-operated calcium channel activity 1/164 10/18639 0.1 11.365243902439 0.0846038602773245 0.36901007707051 GO:0030957 Tat protein binding 1/164 10/18639 0.1 11.365243902439 0.0846038602773245 0.36901007707051 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/164 10/18639 0.1 11.365243902439 0.0846038602773245 0.36901007707051 GO:0035256 G protein-coupled glutamate receptor binding 1/164 10/18639 0.1 11.365243902439 0.0846038602773245 0.36901007707051 GO:0035374 chondroitin sulfate binding 1/164 10/18639 0.1 11.365243902439 0.0846038602773245 0.36901007707051 GO:0019212 phosphatase inhibitor activity 2/164 56/18639 0.0357142857142857 4.05901567944251 0.0870937051983232 0.36901007707051 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/164 349/18639 0.0171919770773639 1.95391012649382 0.0883886403095201 0.36901007707051 GO:0008236 serine-type peptidase activity 4/164 194/18639 0.0206185567010309 2.34334925823485 0.092347857862264 0.36901007707051 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/164 58/18639 0.0344827586206897 3.9190496215307 0.0924459278597028 0.36901007707051 GO:0061980 regulatory RNA binding 2/164 58/18639 0.0344827586206897 3.9190496215307 0.0924459278597028 0.36901007707051 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/164 11/18639 0.0909090909090909 10.3320399113082 0.0926625304643726 0.36901007707051 GO:0019215 intermediate filament binding 1/164 11/18639 0.0909090909090909 10.3320399113082 0.0926625304643726 0.36901007707051 GO:0050786 RAGE receptor binding 1/164 11/18639 0.0909090909090909 10.3320399113082 0.0926625304643726 0.36901007707051 GO:0050998 nitric-oxide synthase binding 1/164 11/18639 0.0909090909090909 10.3320399113082 0.0926625304643726 0.36901007707051 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/164 11/18639 0.0909090909090909 10.3320399113082 0.0926625304643726 0.36901007707051 GO:1990948 ubiquitin ligase inhibitor activity 1/164 11/18639 0.0909090909090909 10.3320399113082 0.0926625304643726 0.36901007707051 GO:0017171 serine hydrolase activity 4/164 198/18639 0.0202020202020202 2.2960088691796 0.0976912799214191 0.374320729800858 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/164 60/18639 0.0333333333333333 3.78841463414634 0.0978914069443164 0.374320729800858 GO:0004859 phospholipase inhibitor activity 1/164 12/18639 0.0833333333333333 9.47103658536585 0.100650685124231 0.374320729800858 GO:0005049 nuclear export signal receptor activity 1/164 12/18639 0.0833333333333333 9.47103658536585 0.100650685124231 0.374320729800858 GO:0005078 MAP-kinase scaffold activity 1/164 12/18639 0.0833333333333333 9.47103658536585 0.100650685124231 0.374320729800858 GO:0035497 cAMP response element binding 1/164 12/18639 0.0833333333333333 9.47103658536585 0.100650685124231 0.374320729800858 GO:0070679 inositol 1,4,5 trisphosphate binding 1/164 12/18639 0.0833333333333333 9.47103658536585 0.100650685124231 0.374320729800858 GO:1990459 transferrin receptor binding 1/164 12/18639 0.0833333333333333 9.47103658536585 0.100650685124231 0.374320729800858 GO:0030246 carbohydrate binding 5/164 280/18639 0.0178571428571429 2.02950783972125 0.101600883945754 0.374757358816306 GO:0017154 semaphorin receptor activity 1/164 13/18639 0.0769230769230769 8.74249530956848 0.108568937534154 0.385206272438587 GO:0043560 insulin receptor substrate binding 1/164 13/18639 0.0769230769230769 8.74249530956848 0.108568937534154 0.385206272438587 GO:0045159 myosin II binding 1/164 13/18639 0.0769230769230769 8.74249530956848 0.108568937534154 0.385206272438587 GO:0019843 rRNA binding 2/164 65/18639 0.0307692307692308 3.49699812382739 0.111881539519386 0.385206272438587 GO:0051015 actin filament binding 4/164 209/18639 0.0191387559808612 2.17516629711752 0.113108007126943 0.385206272438587 GO:0004065 arylsulfatase activity 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0008191 metalloendopeptidase inhibitor activity 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0008195 phosphatidate phosphatase activity 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0008331 high voltage-gated calcium channel activity 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0008494 translation activator activity 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0032036 myosin heavy chain binding 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0042043 neurexin family protein binding 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0044548 S100 protein binding 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0046030 inositol trisphosphate phosphatase activity 1/164 14/18639 0.0714285714285714 8.11803135888502 0.116417895670329 0.385206272438587 GO:0016922 nuclear receptor binding 3/164 137/18639 0.0218978102189781 2.48873954068008 0.120277973231413 0.39507363470172 GO:0030553 cGMP binding 1/164 15/18639 0.0666666666666667 7.57682926829268 0.124198162253419 0.399208378671705 GO:0051371 muscle alpha-actinin binding 1/164 15/18639 0.0666666666666667 7.57682926829268 0.124198162253419 0.399208378671705 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/164 15/18639 0.0666666666666667 7.57682926829268 0.124198162253419 0.399208378671705 GO:0004713 protein tyrosine kinase activity 3/164 140/18639 0.0214285714285714 2.43540940766551 0.126081244713034 0.402386951211812 GO:0004708 MAP kinase kinase activity 1/164 16/18639 0.0625 7.10327743902439 0.131910334793714 0.415102452148049 GO:0055102 lipase inhibitor activity 1/164 16/18639 0.0625 7.10327743902439 0.131910334793714 0.415102452148049 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 7/164 484/18639 0.0144628099173554 1.64373362225358 0.13570255555837 0.424070486119906 GO:0008484 sulfuric ester hydrolase activity 1/164 17/18639 0.0588235294117647 6.68543758967001 0.139555005635889 0.425230893600987 GO:0045236 CXCR chemokine receptor binding 1/164 17/18639 0.0588235294117647 6.68543758967001 0.139555005635889 0.425230893600987 GO:0070492 oligosaccharide binding 1/164 17/18639 0.0588235294117647 6.68543758967001 0.139555005635889 0.425230893600987 GO:0140297 DNA-binding transcription factor binding 7/164 488/18639 0.014344262295082 1.63026039584166 0.139853716117658 0.425230893600987 GO:0003725 double-stranded RNA binding 2/164 75/18639 0.0266666666666667 3.03073170731707 0.141236658350799 0.426553666160131 GO:0001216 DNA-binding transcription activator activity 7/164 491/18639 0.0142566191446029 1.62029953802593 0.143007573557454 0.429022720672361 GO:0003746 translation elongation factor activity 1/164 18/18639 0.0555555555555556 6.3140243902439 0.147132762003396 0.434880864705416 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/164 18/18639 0.0555555555555556 6.3140243902439 0.147132762003396 0.434880864705416 GO:0004175 endopeptidase activity 6/164 405/18639 0.0148148148148148 1.68373983739837 0.147859493999842 0.434880864705416 GO:0019199 transmembrane receptor protein kinase activity 2/164 78/18639 0.0256410256410256 2.91416510318949 0.150339702228879 0.439304324694776 GO:0033293 monocarboxylic acid binding 2/164 79/18639 0.0253164556962025 2.87727693732634 0.153399936222186 0.440442302019669 GO:0003756 protein disulfide isomerase activity 1/164 19/18639 0.0526315789473684 5.98170731707317 0.154644186042462 0.440442302019669 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/164 19/18639 0.0526315789473684 5.98170731707317 0.154644186042462 0.440442302019669 GO:0042577 lipid phosphatase activity 1/164 19/18639 0.0526315789473684 5.98170731707317 0.154644186042462 0.440442302019669 GO:0001618 virus receptor activity 2/164 81/18639 0.0246913580246914 2.80623306233062 0.159556497645488 0.449039091080792 GO:0016004 phospholipase activator activity 1/164 20/18639 0.05 5.68262195121951 0.162089854865718 0.449039091080792 GO:0042288 MHC class I protein binding 1/164 20/18639 0.05 5.68262195121951 0.162089854865718 0.449039091080792 GO:0052745 inositol phosphate phosphatase activity 1/164 20/18639 0.05 5.68262195121951 0.162089854865718 0.449039091080792 GO:0140272 exogenous protein binding 2/164 82/18639 0.024390243902439 2.77201070791196 0.162651937435931 0.449039091080792 GO:0001846 opsonin binding 1/164 21/18639 0.0476190476190476 5.41202090592335 0.169470340595458 0.450533277069391 GO:0009975 cyclase activity 1/164 21/18639 0.0476190476190476 5.41202090592335 0.169470340595458 0.450533277069391 GO:0010314 phosphatidylinositol-5-phosphate binding 1/164 21/18639 0.0476190476190476 5.41202090592335 0.169470340595458 0.450533277069391 GO:0036122 BMP binding 1/164 21/18639 0.0476190476190476 5.41202090592335 0.169470340595458 0.450533277069391 GO:0072542 protein phosphatase activator activity 1/164 21/18639 0.0476190476190476 5.41202090592335 0.169470340595458 0.450533277069391 GO:0016209 antioxidant activity 2/164 86/18639 0.0232558139534884 2.6430799773114 0.175138049049098 0.450533277069391 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/164 22/18639 0.0454545454545455 5.1660199556541 0.176786210406519 0.450533277069391 GO:0050321 tau-protein kinase activity 1/164 22/18639 0.0454545454545455 5.1660199556541 0.176786210406519 0.450533277069391 GO:0061133 endopeptidase activator activity 1/164 22/18639 0.0454545454545455 5.1660199556541 0.176786210406519 0.450533277069391 GO:0008081 phosphoric diester hydrolase activity 2/164 87/18639 0.0229885057471264 2.61269974768713 0.178283579211733 0.450533277069391 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/164 88/18639 0.0227272727272727 2.58300997782705 0.181437898480954 0.450533277069391 GO:0003887 DNA-directed DNA polymerase activity 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0005158 insulin receptor binding 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0005212 structural constituent of eye lens 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0016849 phosphorus-oxygen lyase activity 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0017134 fibroblast growth factor binding 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0043274 phospholipase binding 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0099186 structural constituent of postsynapse 1/164 23/18639 0.0434782608695652 4.94141039236479 0.184038026568808 0.450533277069391 GO:0003727 single-stranded RNA binding 2/164 89/18639 0.0224719101123595 2.55398739380652 0.184600612006744 0.450533277069391 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0005540 hyaluronic acid binding 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0030215 semaphorin receptor binding 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0035035 histone acetyltransferase binding 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0048027 mRNA 5'-UTR binding 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0050431 transforming growth factor beta binding 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0060229 lipase activator activity 1/164 24/18639 0.0416666666666667 4.73551829268293 0.191226346489453 0.450533277069391 GO:0000030 mannosyltransferase activity 1/164 25/18639 0.04 4.54609756097561 0.198351722754601 0.455399363467195 GO:0001848 complement binding 1/164 25/18639 0.04 4.54609756097561 0.198351722754601 0.455399363467195 GO:0019211 phosphatase activator activity 1/164 25/18639 0.04 4.54609756097561 0.198351722754601 0.455399363467195 GO:0042974 nuclear retinoic acid receptor binding 1/164 25/18639 0.04 4.54609756097561 0.198351722754601 0.455399363467195 GO:0120020 cholesterol transfer activity 1/164 25/18639 0.04 4.54609756097561 0.198351722754601 0.455399363467195 GO:0003730 mRNA 3'-UTR binding 4/164 262/18639 0.0152671755725191 1.73515174083039 0.200074220270721 0.457022330567636 GO:0043021 ribonucleoprotein complex binding 3/164 177/18639 0.0169491525423729 1.92631252583712 0.204629995502658 0.459883663815357 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/164 26/18639 0.0384615384615385 4.37124765478424 0.20541470317086 0.459883663815357 GO:0004435 phosphatidylinositol phospholipase C activity 1/164 26/18639 0.0384615384615385 4.37124765478424 0.20541470317086 0.459883663815357 GO:0005112 Notch binding 1/164 26/18639 0.0384615384615385 4.37124765478424 0.20541470317086 0.459883663815357 GO:0001671 ATPase activator activity 1/164 27/18639 0.037037037037037 4.20934959349593 0.212415830806382 0.461773545231265 GO:0005044 scavenger receptor activity 1/164 27/18639 0.037037037037037 4.20934959349593 0.212415830806382 0.461773545231265 GO:0005104 fibroblast growth factor receptor binding 1/164 27/18639 0.037037037037037 4.20934959349593 0.212415830806382 0.461773545231265 GO:0015252 proton channel activity 1/164 27/18639 0.037037037037037 4.20934959349593 0.212415830806382 0.461773545231265 GO:0023026 MHC class II protein complex binding 1/164 27/18639 0.037037037037037 4.20934959349593 0.212415830806382 0.461773545231265 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/164 27/18639 0.037037037037037 4.20934959349593 0.212415830806382 0.461773545231265 GO:0045499 chemorepellent activity 1/164 28/18639 0.0357142857142857 4.05901567944251 0.219355644031599 0.463427416968168 GO:0046875 ephrin receptor binding 1/164 28/18639 0.0357142857142857 4.05901567944251 0.219355644031599 0.463427416968168 GO:0051019 mitogen-activated protein kinase binding 1/164 28/18639 0.0357142857142857 4.05901567944251 0.219355644031599 0.463427416968168 GO:0051393 alpha-actinin binding 1/164 28/18639 0.0357142857142857 4.05901567944251 0.219355644031599 0.463427416968168 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/164 28/18639 0.0357142857142857 4.05901567944251 0.219355644031599 0.463427416968168 GO:0097718 disordered domain specific binding 1/164 28/18639 0.0357142857142857 4.05901567944251 0.219355644031599 0.463427416968168 GO:1901981 phosphatidylinositol phosphate binding 3/164 185/18639 0.0162162162162162 1.84301252471984 0.222911594367047 0.468739333949397 GO:0003785 actin monomer binding 1/164 29/18639 0.0344827586206897 3.9190496215307 0.226234676559611 0.469150250930069 GO:0004629 phospholipase C activity 1/164 29/18639 0.0344827586206897 3.9190496215307 0.226234676559611 0.469150250930069 GO:0106222 lncRNA binding 1/164 29/18639 0.0344827586206897 3.9190496215307 0.226234676559611 0.469150250930069 GO:0048019 receptor antagonist activity 1/164 30/18639 0.0333333333333333 3.78841463414634 0.233053457486222 0.47670025394909 GO:0051721 protein phosphatase 2A binding 1/164 30/18639 0.0333333333333333 3.78841463414634 0.233053457486222 0.47670025394909 GO:0098918 structural constituent of synapse 1/164 30/18639 0.0333333333333333 3.78841463414634 0.233053457486222 0.47670025394909 GO:0071813 lipoprotein particle binding 1/164 32/18639 0.03125 3.5516387195122 0.24651235806986 0.495225719336773 GO:0071814 protein-lipid complex binding 1/164 32/18639 0.03125 3.5516387195122 0.24651235806986 0.495225719336773 GO:0120015 sterol transfer activity 1/164 32/18639 0.03125 3.5516387195122 0.24651235806986 0.495225719336773 GO:0140142 nucleocytoplasmic carrier activity 1/164 32/18639 0.03125 3.5516387195122 0.24651235806986 0.495225719336773 GO:0004222 metalloendopeptidase activity 2/164 110/18639 0.0181818181818182 2.06640798226164 0.252319974570835 0.501846171517351 GO:0019956 chemokine binding 1/164 33/18639 0.0303030303030303 3.4440133037694 0.253153513187641 0.501846171517351 GO:0071889 14-3-3 protein binding 1/164 33/18639 0.0303030303030303 3.4440133037694 0.253153513187641 0.501846171517351 GO:1902936 phosphatidylinositol bisphosphate binding 2/164 111/18639 0.018018018018018 2.04779169413316 0.255579204276647 0.504432640019698 GO:0015035 protein-disulfide reductase activity 1/164 34/18639 0.0294117647058824 3.34271879483501 0.25973648770324 0.505980170850467 GO:0019825 oxygen binding 1/164 34/18639 0.0294117647058824 3.34271879483501 0.25973648770324 0.505980170850467 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/164 34/18639 0.0294117647058824 3.34271879483501 0.25973648770324 0.505980170850467 GO:0034061 DNA polymerase activity 1/164 35/18639 0.0285714285714286 3.24721254355401 0.266261788214751 0.514382969506142 GO:0001221 transcription coregulator binding 2/164 115/18639 0.0173913043478261 1.97656415694592 0.268622217408763 0.514382969506142 GO:0035401 histone H3Y41 kinase activity 2/164 115/18639 0.0173913043478261 1.97656415694592 0.268622217408763 0.514382969506142 GO:0140801 histone H2AXY142 kinase activity 2/164 115/18639 0.0173913043478261 1.97656415694592 0.268622217408763 0.514382969506142 GO:0003712 transcription coregulator activity 6/164 495/18639 0.0121212121212121 1.37760532150776 0.270603942054171 0.514809906888254 GO:0055106 ubiquitin-protein transferase regulator activity 1/164 36/18639 0.0277777777777778 3.15701219512195 0.272729916936143 0.514809906888254 GO:0005543 phospholipid binding 6/164 497/18639 0.0120724346076459 1.37206163812141 0.273600234527079 0.514809906888254 GO:0005516 calmodulin binding 3/164 207/18639 0.0144927536231884 1.64713679745493 0.274600457376998 0.514809906888254 GO:0019001 guanyl nucleotide binding 5/164 400/18639 0.0125 1.42065548780488 0.276816037094981 0.514809906888254 GO:0032561 guanyl ribonucleotide binding 5/164 400/18639 0.0125 1.42065548780488 0.276816037094981 0.514809906888254 GO:0023023 MHC protein complex binding 1/164 37/18639 0.027027027027027 3.07168754119974 0.279141371734964 0.514809906888254 GO:0030551 cyclic nucleotide binding 1/164 37/18639 0.027027027027027 3.07168754119974 0.279141371734964 0.514809906888254 GO:0042805 actinin binding 1/164 37/18639 0.027027027027027 3.07168754119974 0.279141371734964 0.514809906888254 GO:0005501 retinoid binding 1/164 38/18639 0.0263157894736842 2.99085365853659 0.285496646169728 0.5222499625056 GO:0019840 isoprenoid binding 1/164 38/18639 0.0263157894736842 2.99085365853659 0.285496646169728 0.5222499625056 GO:0051082 unfolded protein binding 2/164 121/18639 0.0165289256198347 1.87855271114695 0.288177113410696 0.525019032529608 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/164 122/18639 0.0163934426229508 1.86315473810476 0.291432051231008 0.528808157475619 GO:0015036 disulfide oxidoreductase activity 1/164 40/18639 0.025 2.84131097560976 0.298040606858028 0.538627602755473 GO:0001530 lipopolysaccharide binding 1/164 41/18639 0.024390243902439 2.77201070791196 0.304230259015418 0.545432735286605 GO:0042169 SH2 domain binding 1/164 41/18639 0.024390243902439 2.77201070791196 0.304230259015418 0.545432735286605 GO:0031490 chromatin DNA binding 2/164 128/18639 0.015625 1.7758193597561 0.310916107912336 0.555207335557743 GO:0035591 signaling adaptor activity 2/164 129/18639 0.0155038759689922 1.7620533182076 0.314153902432761 0.55625500272976 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/164 43/18639 0.0232558139534884 2.6430799773114 0.316447290441819 0.55625500272976 GO:0005245 voltage-gated calcium channel activity 1/164 43/18639 0.0232558139534884 2.6430799773114 0.316447290441819 0.55625500272976 GO:0008200 ion channel inhibitor activity 1/164 43/18639 0.0232558139534884 2.6430799773114 0.316447290441819 0.55625500272976 GO:0005262 calcium channel activity 2/164 131/18639 0.0152671755725191 1.73515174083039 0.320619508915854 0.557389371246088 GO:0001223 transcription coactivator binding 1/164 44/18639 0.0227272727272727 2.58300997782705 0.322475610745516 0.557389371246088 GO:0016248 channel inhibitor activity 1/164 44/18639 0.0227272727272727 2.58300997782705 0.322475610745516 0.557389371246088 GO:0043014 alpha-tubulin binding 1/164 44/18639 0.0227272727272727 2.58300997782705 0.322475610745516 0.557389371246088 GO:0005179 hormone activity 2/164 132/18639 0.0151515151515152 1.7220066518847 0.32384693961993 0.557389371246088 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/164 45/18639 0.0222222222222222 2.52560975609756 0.328451088015628 0.557389371246088 GO:0008009 chemokine activity 1/164 45/18639 0.0222222222222222 2.52560975609756 0.328451088015628 0.557389371246088 GO:0051539 4 iron, 4 sulfur cluster binding 1/164 45/18639 0.0222222222222222 2.52560975609756 0.328451088015628 0.557389371246088 GO:0141110 transporter inhibitor activity 1/164 45/18639 0.0222222222222222 2.52560975609756 0.328451088015628 0.557389371246088 GO:0051087 protein-folding chaperone binding 2/164 134/18639 0.0149253731343284 1.69630506006553 0.330290129493155 0.557389371246088 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/164 46/18639 0.0217391304347826 2.4707051961824 0.334374182646447 0.557389371246088 GO:0044325 transmembrane transporter binding 2/164 136/18639 0.0147058823529412 1.6713593974175 0.336716562673553 0.557389371246088 GO:0005504 fatty acid binding 1/164 47/18639 0.0212765957446809 2.41813700051894 0.340245351045628 0.557389371246088 GO:0140693 molecular condensate scaffold activity 1/164 48/18639 0.0208333333333333 2.36775914634146 0.346065045668505 0.557389371246088 GO:0070851 growth factor receptor binding 2/164 139/18639 0.0143884892086331 1.63528689243727 0.346321776374643 0.557389371246088 GO:0140767 enzyme-substrate adaptor activity 2/164 139/18639 0.0143884892086331 1.63528689243727 0.346321776374643 0.557389371246088 GO:0005004 GPI-linked ephrin receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0005008 hepatocyte growth factor receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0005009 insulin receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0005011 macrophage colony-stimulating factor receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0005020 stem cell factor receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0008288 boss receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0035254 glutamate receptor binding 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0036332 placental growth factor receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0038062 protein tyrosine kinase collagen receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0060175 brain-derived neurotrophic factor receptor activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0060590 ATPase regulator activity 1/164 49/18639 0.0204081632653061 2.31943753111 0.351833715052097 0.557389371246088 GO:0005006 epidermal growth factor receptor activity 1/164 50/18639 0.02 2.27304878048781 0.35755180384884 0.557389371246088 GO:0005007 fibroblast growth factor receptor activity 1/164 50/18639 0.02 2.27304878048781 0.35755180384884 0.557389371246088 GO:0005017 platelet-derived growth factor receptor activity 1/164 50/18639 0.02 2.27304878048781 0.35755180384884 0.557389371246088 GO:0005019 platelet-derived growth factor beta-receptor activity 1/164 50/18639 0.02 2.27304878048781 0.35755180384884 0.557389371246088 GO:0019903 protein phosphatase binding 2/164 144/18639 0.0138888888888889 1.57850609756098 0.362227796872341 0.557389371246088 GO:0005010 insulin-like growth factor receptor activity 1/164 51/18639 0.0196078431372549 2.22847919655667 0.363219752860018 0.557389371246088 GO:0005030 neurotrophin receptor activity 1/164 51/18639 0.0196078431372549 2.22847919655667 0.363219752860018 0.557389371246088 GO:0030544 Hsp70 protein binding 1/164 51/18639 0.0196078431372549 2.22847919655667 0.363219752860018 0.557389371246088 GO:0005080 protein kinase C binding 1/164 52/18639 0.0192307692307692 2.18562382739212 0.368837999068914 0.557389371246088 GO:0015085 calcium ion transmembrane transporter activity 2/164 147/18639 0.0136054421768707 1.54629168740667 0.371703103337091 0.557389371246088 GO:0005003 ephrin receptor activity 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0005005 transmembrane-ephrin receptor activity 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0005246 calcium channel regulator activity 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0005544 calcium-dependent phospholipid binding 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0008146 sulfotransferase activity 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0038064 collagen receptor activity 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0051018 protein kinase A binding 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0140296 general transcription initiation factor binding 1/164 53/18639 0.0188679245283019 2.14438564196963 0.374406975673675 0.557389371246088 GO:0022804 active transmembrane transporter activity 5/164 457/18639 0.0109409190371991 1.24346213374606 0.375308843305699 0.557389371246088 GO:0141003 histone H2AX kinase activity 4/164 354/18639 0.0112994350282486 1.28420835055808 0.378795499876736 0.560548198209687 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/164 54/18639 0.0185185185185185 2.10467479674797 0.379927112119899 0.560548198209687 GO:0140996 histone H3 kinase activity 4/164 357/18639 0.0112044817927171 1.27341668374667 0.384778844125957 0.565851241361702 GO:0035173 histone kinase activity 4/164 360/18639 0.0111111111111111 1.26280487804878 0.390755885202826 0.572769212838018 GO:0005506 iron ion binding 2/164 154/18639 0.012987012987013 1.47600570161546 0.39358860625832 0.575048288364429 GO:0004601 peroxidase activity 1/164 57/18639 0.0175438596491228 1.99390243902439 0.396198719351557 0.575891621080893 GO:0042578 phosphoric ester hydrolase activity 4/164 363/18639 0.0110192837465565 1.25236847409796 0.396725338966838 0.575891621080893 GO:0001786 phosphatidylserine binding 1/164 59/18639 0.0169491525423729 1.92631252583712 0.406809963937762 0.58115709133966 GO:0015459 potassium channel regulator activity 1/164 59/18639 0.0169491525423729 1.92631252583712 0.406809963937762 0.58115709133966 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/164 59/18639 0.0169491525423729 1.92631252583712 0.406809963937762 0.58115709133966 GO:0036002 pre-mRNA binding 1/164 59/18639 0.0169491525423729 1.92631252583712 0.406809963937762 0.58115709133966 GO:0070888 E-box binding 1/164 59/18639 0.0169491525423729 1.92631252583712 0.406809963937762 0.58115709133966 GO:0099106 ion channel regulator activity 2/164 160/18639 0.0125 1.42065548780488 0.412072653985494 0.58681232371352 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/164 268/18639 0.0111940298507463 1.27222879504914 0.42038042976528 0.596754553294561 GO:0005525 GTP binding 4/164 378/18639 0.0105820105820106 1.20267131242741 0.426415671756293 0.602906405054083 GO:0005096 GTPase activator activity 3/164 271/18639 0.011070110701107 1.25814508145081 0.427393651582784 0.602906405054083 GO:0016874 ligase activity 2/164 167/18639 0.0119760479041916 1.36110705418431 0.433283382107941 0.609304756089292 GO:0016247 channel regulator activity 2/164 168/18639 0.0119047619047619 1.35300522648084 0.436280558214371 0.609581874635435 GO:0005126 cytokine receptor binding 3/164 275/18639 0.0109090909090909 1.23984478935698 0.436698732293776 0.609581874635435 GO:0120013 lipid transfer activity 1/164 65/18639 0.0153846153846154 1.7484990619137 0.437544323349435 0.609581874635435 GO:0141108 transporter regulator activity 2/164 170/18639 0.0117647058823529 1.337087517934 0.442249336522143 0.614235189614088 GO:0001217 DNA-binding transcription repressor activity 3/164 278/18639 0.0107913669064748 1.22646516932795 0.443641062746497 0.614272240725919 GO:0016500 protein-hormone receptor activity 1/164 67/18639 0.0149253731343284 1.69630506006553 0.447433196133256 0.615733756146682 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/164 67/18639 0.0149253731343284 1.69630506006553 0.447433196133256 0.615733756146682 GO:0031267 small GTPase binding 3/164 283/18639 0.0106007067137809 1.20479617340343 0.455137617113919 0.624426608845316 GO:0035091 phosphatidylinositol binding 3/164 284/18639 0.0105633802816901 1.20055393335623 0.457425342044664 0.625657762675072 GO:0016782 transferase activity, transferring sulphur-containing groups 1/164 70/18639 0.0142857142857143 1.623606271777 0.461943406759814 0.629922827399746 GO:0005319 lipid transporter activity 2/164 178/18639 0.0112359550561798 1.27699369690326 0.465771979112078 0.633224745016421 GO:0042379 chemokine receptor binding 1/164 72/18639 0.0138888888888889 1.57850609756098 0.471405840527711 0.637245470860861 GO:0016853 isomerase activity 2/164 180/18639 0.0111111111111111 1.26280487804878 0.471561648437037 0.637245470860861 GO:0008237 metallopeptidase activity 2/164 184/18639 0.0108695652173913 1.2353525980912 0.483028198544929 0.650786495045563 GO:0044183 protein folding chaperone 1/164 75/18639 0.0133333333333333 1.51536585365854 0.485290242999025 0.651882415968839 GO:0001664 G protein-coupled receptor binding 3/164 297/18639 0.0101010101010101 1.1480044345898 0.486785383743679 0.651944710370999 GO:0051536 iron-sulfur cluster binding 1/164 76/18639 0.0131578947368421 1.49542682926829 0.489837344924696 0.654085475418733 GO:0031406 carboxylic acid binding 2/164 187/18639 0.0106951871657754 1.21553410721273 0.491527636427595 0.654279510660242 GO:0003724 RNA helicase activity 1/164 77/18639 0.012987012987013 1.47600570161546 0.494344519165516 0.654279510660242 GO:0051540 metal cluster binding 1/164 77/18639 0.012987012987013 1.47600570161546 0.494344519165516 0.654279510660242 GO:0043177 organic acid binding 2/164 189/18639 0.0105820105820106 1.20267131242741 0.497145303159896 0.656056851677283 GO:0019902 phosphatase binding 2/164 190/18639 0.0105263157894737 1.19634146341463 0.499939405186613 0.657815006824491 GO:0008186 ATP-dependent activity, acting on RNA 1/164 79/18639 0.0126582278481013 1.43863846866317 0.503240475446673 0.660228029011671 GO:0005254 chloride channel activity 1/164 83/18639 0.0120481927710843 1.36930649426976 0.520568387369716 0.676466278891247 GO:0008135 translation factor activity, RNA binding 1/164 83/18639 0.0120481927710843 1.36930649426976 0.520568387369716 0.676466278891247 GO:0030165 PDZ domain binding 1/164 83/18639 0.0120481927710843 1.36930649426976 0.520568387369716 0.676466278891247 GO:0004860 protein kinase inhibitor activity 1/164 84/18639 0.0119047619047619 1.35300522648084 0.524805657496433 0.676466278891247 GO:0051117 ATPase binding 1/164 84/18639 0.0119047619047619 1.35300522648084 0.524805657496433 0.676466278891247 GO:0180051 translation factor activity 1/164 84/18639 0.0119047619047619 1.35300522648084 0.524805657496433 0.676466278891247 GO:0051020 GTPase binding 3/164 315/18639 0.00952380952380952 1.08240418118467 0.526140439137636 0.676466278891247 GO:0004674 protein serine/threonine kinase activity 4/164 433/18639 0.0092378752886836 1.04990705796203 0.531193557765345 0.681017381750443 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/164 86/18639 0.0116279069767442 1.3215399886557 0.533168853388715 0.68160790916171 GO:0003714 transcription corepressor activity 2/164 204/18639 0.00980392156862745 1.11423959827834 0.538001638388019 0.685837782647616 GO:0019210 kinase inhibitor activity 1/164 90/18639 0.0111111111111111 1.26280487804878 0.549458869670538 0.69846466483543 GO:0072341 modified amino acid binding 1/164 91/18639 0.010989010989011 1.24892790136693 0.553442305185878 0.701546584038437 GO:0005216 monoatomic ion channel activity 4/164 448/18639 0.00892857142857143 1.01475391986063 0.558172581681718 0.705555229653857 GO:0016410 N-acyltransferase activity 1/164 94/18639 0.0106382978723404 1.20906850025947 0.565183793328152 0.712416546211957 GO:0005261 monoatomic cation channel activity 3/164 341/18639 0.00879765395894428 0.999874830126601 0.579945451165929 0.728981712359408 GO:0005253 monoatomic anion channel activity 1/164 103/18639 0.00970873786407767 1.10342173810088 0.598598607196561 0.736458755875003 GO:0004497 monooxygenase activity 1/164 106/18639 0.00943396226415094 1.07219282098481 0.609159558247267 0.736458755875003 GO:0005125 cytokine activity 2/164 234/18639 0.00854700854700855 0.971388367729831 0.612683414264243 0.736458755875003 GO:0106310 protein serine kinase activity 3/164 361/18639 0.00831024930747922 0.944480102695764 0.61864832253651 0.736458755875003 GO:0004620 phospholipase activity 1/164 109/18639 0.00917431192660551 1.04268292682927 0.619444298434257 0.736458755875003 GO:0005549 odorant binding 1/164 111/18639 0.00900900900900901 1.02389584706658 0.62615089519923 0.736458755875003 GO:0030695 GTPase regulator activity 4/164 489/18639 0.0081799591002045 0.929672302857998 0.627451591628961 0.736458755875003 GO:0060589 nucleoside-triphosphatase regulator activity 4/164 490/18639 0.00816326530612245 0.927775012444002 0.629053627410443 0.736458755875003 GO:0043022 ribosome binding 1/164 112/18639 0.00892857142857143 1.01475391986063 0.629460008605281 0.736458755875003 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/164 243/18639 0.00823045267489712 0.935411020776875 0.633226763073374 0.736458755875003 GO:0046982 protein heterodimerization activity 3/164 369/18639 0.00813008130081301 0.924003569303986 0.633443876080583 0.736458755875003 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0004711 ribosomal protein S6 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0035175 histone H3S10 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0035979 histone H2AXS139 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0044022 histone H3S28 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0044023 histone H4S1 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0044024 histone H2AS1 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0044025 histone H2BS14 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0072354 histone H3T3 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0072371 histone H2AS121 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0140823 histone H2BS36 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0140855 histone H3S57 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0140995 histone H2A kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0140997 histone H4 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0140998 histone H2B kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:1990244 histone H2AT120 kinase activity 2/164 245/18639 0.00816326530612245 0.927775012444002 0.63767563732685 0.736458755875003 GO:0017124 SH3 domain binding 1/164 115/18639 0.00869565217391304 0.988282078472959 0.63921368404509 0.736458755875003 GO:0004677 DNA-dependent protein kinase activity 2/164 246/18639 0.00813008130081301 0.924003569303986 0.639884273852875 0.736458755875003 GO:0140857 histone H3T45 kinase activity 2/164 246/18639 0.00813008130081301 0.924003569303986 0.639884273852875 0.736458755875003 GO:0035402 histone H3T11 kinase activity 2/164 247/18639 0.00809716599190283 0.920262664165103 0.642082392817048 0.736458755875003 GO:0035403 histone H3T6 kinase activity 2/164 247/18639 0.00809716599190283 0.920262664165103 0.642082392817048 0.736458755875003 GO:0042393 histone binding 2/164 247/18639 0.00809716599190283 0.920262664165103 0.642082392817048 0.736458755875003 GO:0004679 AMP-activated protein kinase activity 2/164 248/18639 0.00806451612903226 0.91655192761605 0.644270007097264 0.736458755875003 GO:1990782 protein tyrosine kinase binding 1/164 117/18639 0.00854700854700855 0.971388367729831 0.645573931966083 0.736458755875003 GO:0140104 molecular carrier activity 2/164 249/18639 0.00803212851405622 0.912870996179841 0.646447130156947 0.736458755875003 GO:0003697 single-stranded DNA binding 1/164 121/18639 0.00826446280991736 0.939276355573473 0.65796201253052 0.745428819152846 GO:0015108 chloride transmembrane transporter activity 1/164 121/18639 0.00826446280991736 0.939276355573473 0.65796201253052 0.745428819152846 GO:0019887 protein kinase regulator activity 2/164 255/18639 0.00784313725490196 0.891391678622669 0.659290377828518 0.745428819152846 GO:0008528 G protein-coupled peptide receptor activity 1/164 122/18639 0.00819672131147541 0.931577369052379 0.6609911857644 0.745478780937293 GO:0001653 peptide receptor activity 1/164 128/18639 0.0078125 0.887909679878049 0.678614355566231 0.76344115001201 GO:0016298 lipase activity 1/164 130/18639 0.00769230769230769 0.874249530956848 0.684283976261607 0.765989525665978 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/164 130/18639 0.00769230769230769 0.874249530956848 0.684283976261607 0.765989525665978 GO:0031072 heat shock protein binding 1/164 131/18639 0.00763358778625954 0.867575870415193 0.68708139524119 0.76721247607577 GO:0016791 phosphatase activity 2/164 273/18639 0.00732600732600733 0.832618600911284 0.695594954790709 0.774796360534205 GO:0016779 nucleotidyltransferase activity 1/164 136/18639 0.00735294117647059 0.835679698708752 0.700703222109855 0.778559135677617 GO:0030295 protein kinase activator activity 1/164 139/18639 0.00719424460431655 0.817643446218635 0.708591700420145 0.78538488962824 GO:0022843 voltage-gated monoatomic cation channel activity 1/164 143/18639 0.00699300699300699 0.794772300869862 0.718789103913198 0.794729967471595 GO:0019207 kinase regulator activity 2/164 287/18639 0.00696864111498258 0.792003059403416 0.721587363090425 0.795868415173263 GO:0019209 kinase activator activity 1/164 148/18639 0.00675675675675676 0.767921885299934 0.731038447753621 0.799052029605446 GO:0008509 monoatomic anion transmembrane transporter activity 1/164 149/18639 0.00671140939597315 0.762768047143559 0.733423916066228 0.799052029605446 GO:0019842 vitamin binding 1/164 150/18639 0.00666666666666667 0.757682926829268 0.73578835510166 0.799052029605446 GO:0000510 H3-H4 histone complex chaperone activity 1/164 151/18639 0.00662251655629139 0.752665159101922 0.738131949117741 0.799052029605446 GO:0140584 chromatin extrusion motor activity 1/164 151/18639 0.00662251655629139 0.752665159101922 0.738131949117741 0.799052029605446 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/164 151/18639 0.00662251655629139 0.752665159101922 0.738131949117741 0.799052029605446 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/164 151/18639 0.00662251655629139 0.752665159101922 0.738131949117741 0.799052029605446 GO:0015616 DNA translocase activity 1/164 152/18639 0.00657894736842105 0.747713414634146 0.740454880767714 0.799052029605446 GO:0140674 ATP-dependent histone chaperone activity 1/164 152/18639 0.00657894736842105 0.747713414634146 0.740454880767714 0.799052029605446 GO:0061775 cohesin loader activity 1/164 153/18639 0.0065359477124183 0.742826398852224 0.742757331114124 0.79961913636688 GO:0004386 helicase activity 1/164 155/18639 0.00645161290322581 0.73324154209284 0.747301504275464 0.80259111437699 GO:0140658 ATP-dependent chromatin remodeler activity 1/164 158/18639 0.00632911392405063 0.719319234331584 0.753968590858107 0.807823490205114 GO:0003689 DNA clamp loader activity 1/164 160/18639 0.00625 0.710327743902439 0.758315888553692 0.810551424819861 GO:0140713 histone chaperone activity 1/164 164/18639 0.00609756097560976 0.693002676977989 0.766782751251102 0.817659331902833 GO:0015103 inorganic anion transmembrane transporter activity 1/164 165/18639 0.00606060606060606 0.68880266075388 0.768852988263 0.817928710918085 GO:0005244 voltage-gated monoatomic ion channel activity 1/164 173/18639 0.00578034682080925 0.656950514591851 0.78477058460623 0.83289330913397 GO:0003823 antigen binding 1/164 174/18639 0.00574712643678161 0.653174936921783 0.786682077302243 0.832957493614139 GO:0022832 voltage-gated channel activity 1/164 175/18639 0.00571428571428571 0.649442508710801 0.788576696274484 0.833003552402624 GO:0140097 catalytic activity, acting on DNA 2/164 336/18639 0.00595238095238095 0.676502613240418 0.798288920431675 0.840699108089927 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/164 181/18639 0.00552486187845304 0.627914027759062 0.799598262805531 0.840699108089927 GO:0140597 protein carrier chaperone 1/164 188/18639 0.00531914893617021 0.604534250129735 0.811736866436768 0.851472237521086 GO:0016758 hexosyltransferase activity 1/164 197/18639 0.0050761421319797 0.576915934133961 0.826275653826041 0.864707079585391 GO:0016829 lyase activity 1/164 200/18639 0.005 0.568262195121951 0.830869466880558 0.867497123193158 GO:0008094 ATP-dependent activity, acting on DNA 1/164 210/18639 0.00476190476190476 0.541202090592335 0.845327638519721 0.880549623458043 GO:0015631 tubulin binding 2/164 385/18639 0.00519480519480519 0.590402280646183 0.855767389652981 0.889365647445361 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/164 229/18639 0.00436681222707424 0.496298860368516 0.869498130648177 0.898617661586118 GO:0000287 magnesium ion binding 1/164 230/18639 0.00434782608695652 0.494141039236479 0.870660667670106 0.898617661586118 GO:0005085 guanyl-nucleotide exchange factor activity 1/164 230/18639 0.00434782608695652 0.494141039236479 0.870660667670106 0.898617661586118 GO:0003713 transcription coactivator activity 1/164 256/18639 0.00390625 0.443954839939024 0.897525206605821 0.924225041127275 GO:0016757 glycosyltransferase activity 1/164 267/18639 0.00374531835205993 0.42566456563442 0.907147204038096 0.931859788767588 GO:0046873 metal ion transmembrane transporter activity 2/164 450/18639 0.00444444444444444 0.505121951219512 0.909080993931047 0.931859788767588 GO:0008017 microtubule binding 1/164 276/18639 0.0036231884057971 0.411784199363733 0.914347589449924 0.935128216482877 GO:0016755 aminoacyltransferase activity 2/164 496/18639 0.00403225806451613 0.458275963808025 0.935034259887657 0.954116591722099 GO:0022836 gated channel activity 1/164 318/18639 0.00314465408805031 0.357397606994938 0.941261990834733 0.958298406958439 GO:0003924 GTPase activity 1/164 331/18639 0.00302114803625378 0.343360842973989 0.947743964302876 0.962719602564998 GO:0061630 ubiquitin protein ligase activity 1/164 353/18639 0.0028328611898017 0.321961583638499 0.957133914382388 0.969044168354627 GO:0045182 translation regulator activity 1/164 356/18639 0.00280898876404494 0.319248424225815 0.958277010928464 0.969044168354627 GO:0061659 ubiquitin-like protein ligase activity 1/164 372/18639 0.00268817204301075 0.30551730920535 0.963880822616153 0.972525493671006 GO:0140098 catalytic activity, acting on RNA 1/164 387/18639 0.00258397932816537 0.2936755530346 0.968452491713417 0.974952172865856 GO:0016887 ATP hydrolysis activity 1/164 417/18639 0.00239808153477218 0.272547815406212 0.975941209391539 0.980298089790609 GO:0004842 ubiquitin-protein transferase activity 1/164 449/18639 0.0022271714922049 0.253123472214678 0.981989668281377 0.984176727676213 GO:0019787 ubiquitin-like protein transferase activity 1/164 479/18639 0.00208768267223382 0.23727022760833 0.986277692433748 0.986277692433748