ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 13/102 175/18639 0.0742857142857143 13.5746218487395 1.27317804361229e-11 3.50123961993379e-09 GO:0005201 extracellular matrix structural constituent 9/102 168/18639 0.0535714285714286 9.78939075630252 3.54075572738679e-07 4.86853912515684e-05 GO:0005178 integrin binding 8/102 161/18639 0.0496894409937888 9.08001461454147 2.86913430435598e-06 0.000263003977899298 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/102 44/18639 0.0909090909090909 16.6122994652406 9.6984225606138e-05 0.00563632317727931 GO:0019838 growth factor binding 6/102 136/18639 0.0441176470588235 8.06185121107266 0.00010247860322326 0.00563632317727931 GO:0061134 peptidase regulator activity 7/102 226/18639 0.0309734513274336 5.65994273815721 0.000244340310882905 0.0111989309154665 GO:0050840 extracellular matrix binding 4/102 67/18639 0.0597014925373134 10.9095697980685 0.000497324306004748 0.0195377405930437 GO:0001968 fibronectin binding 3/102 30/18639 0.1 18.2735294117647 0.00058019698948508 0.0199442715135496 GO:0005518 collagen binding 4/102 72/18639 0.0555555555555556 10.1519607843137 0.000653721502733694 0.0199748236946406 GO:0030246 carbohydrate binding 7/102 280/18639 0.025 4.56838235294118 0.000877488968506065 0.0241309466339168 GO:0005522 profilin binding 2/102 10/18639 0.2 36.5470588235294 0.00129681960534532 0.0324204901336331 GO:0048407 platelet-derived growth factor binding 2/102 11/18639 0.181818181818182 33.2245989304813 0.00157935060453196 0.0361934513538574 GO:0004857 enzyme inhibitor activity 8/102 416/18639 0.0192307692307692 3.51414027149321 0.00203111127523691 0.0429658154377039 GO:0031994 insulin-like growth factor I binding 2/102 13/18639 0.153846153846154 28.1131221719457 0.00222387312361873 0.0436832220710822 GO:0019888 protein phosphatase regulator activity 4/102 107/18639 0.0373831775700935 6.83122594832325 0.00283430102157195 0.0511521582315219 GO:0004864 protein phosphatase inhibitor activity 3/102 53/18639 0.0566037735849057 10.3435072142064 0.00305646075413042 0.0511521582315219 GO:0061135 endopeptidase regulator activity 5/102 184/18639 0.0271739130434783 4.96563299232737 0.00341718648033523 0.0511521582315219 GO:0019212 phosphatase inhibitor activity 3/102 56/18639 0.0535714285714286 9.78939075630252 0.00357415997654946 0.0511521582315219 GO:0016504 peptidase activator activity 3/102 57/18639 0.0526315789473684 9.61764705882353 0.00375787738146731 0.0511521582315219 GO:0070492 oligosaccharide binding 2/102 17/18639 0.117647058823529 21.4982698961938 0.00382261993488682 0.0511521582315219 GO:0019208 phosphatase regulator activity 4/102 117/18639 0.0341880341880342 6.2473604826546 0.00390616481040713 0.0511521582315219 GO:0003746 translation elongation factor activity 2/102 18/18639 0.111111111111111 20.3039215686275 0.00428515916500918 0.0535644895626148 GO:0005520 insulin-like growth factor binding 2/102 19/18639 0.105263157894737 19.2352941176471 0.0047722765039394 0.0570598277644928 GO:0019843 rRNA binding 3/102 65/18639 0.0461538461538462 8.43393665158371 0.00543583290128017 0.0622855853271686 GO:0005539 glycosaminoglycan binding 5/102 242/18639 0.0206611570247934 3.77552260573651 0.0106418334671927 0.115661858923864 GO:0043236 laminin binding 2/102 29/18639 0.0689655172413793 12.6024340770791 0.010935303025529 0.115661858923864 GO:0004866 endopeptidase inhibitor activity 4/102 161/18639 0.0248447204968944 4.54000730727073 0.0118444519029104 0.117927560838378 GO:0008083 growth factor activity 4/102 162/18639 0.0246913580246914 4.5119825708061 0.0120943997226844 0.117927560838378 GO:0017147 Wnt-protein binding 2/102 31/18639 0.0645161290322581 11.7893738140417 0.0124359973247744 0.117927560838378 GO:0030414 peptidase inhibitor activity 4/102 169/18639 0.0236686390532544 4.32509571876088 0.0139391169070264 0.127775238314408 GO:0008201 heparin binding 4/102 172/18639 0.0232558139534884 4.24965800273598 0.0147814597938687 0.131125853010126 GO:0004867 serine-type endopeptidase inhibitor activity 3/102 95/18639 0.0315789473684211 5.77058823529412 0.015314048570646 0.131605104903989 GO:1901681 sulfur compound binding 5/102 275/18639 0.0181818181818182 3.32245989304813 0.01762002372566 0.146833531047167 GO:0005200 structural constituent of cytoskeleton 3/102 112/18639 0.0267857142857143 4.89469537815126 0.0236003740477369 0.189865555967767 GO:0030547 signaling receptor inhibitor activity 2/102 44/18639 0.0454545454545455 8.30614973262032 0.0241647071231704 0.189865555967767 GO:0140693 molecular condensate scaffold activity 2/102 48/18639 0.0416666666666667 7.61397058823529 0.0284110583392673 0.217028917869403 GO:0005544 calcium-dependent phospholipid binding 2/102 53/18639 0.0377358490566038 6.89567147613762 0.0341037692816262 0.250903621952553 GO:0003925 G protein activity 2/102 54/18639 0.037037037037037 6.76797385620915 0.0352914716577722 0.250903621952553 GO:0005179 hormone activity 3/102 132/18639 0.0227272727272727 4.15307486631016 0.0358996916352727 0.250903621952553 GO:0140313 molecular sequestering activity 2/102 55/18639 0.0363636363636364 6.64491978609626 0.0364950722840078 0.250903621952553 GO:0001786 phosphatidylserine binding 2/102 59/18639 0.0338983050847458 6.19441674975075 0.0414643667165019 0.271492877310429 GO:0004879 nuclear receptor activity 2/102 59/18639 0.0338983050847458 6.19441674975075 0.0414643667165019 0.271492877310429 GO:0098531 ligand-modulated transcription factor activity 2/102 60/18639 0.0333333333333333 6.09117647058823 0.0427444057334961 0.273365385504917 GO:0005131 growth hormone receptor binding 1/102 10/18639 0.1 18.2735294117647 0.0534084036038387 0.300239969649483 GO:0030957 Tat protein binding 1/102 10/18639 0.1 18.2735294117647 0.0534084036038387 0.300239969649483 GO:0035374 chondroitin sulfate binding 1/102 10/18639 0.1 18.2735294117647 0.0534084036038387 0.300239969649483 GO:1905394 retromer complex binding 1/102 10/18639 0.1 18.2735294117647 0.0534084036038387 0.300239969649483 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/102 68/18639 0.0294117647058824 5.37456747404844 0.0534973036829987 0.300239969649483 GO:0032934 sterol binding 2/102 68/18639 0.0294117647058824 5.37456747404844 0.0534973036829987 0.300239969649483 GO:0019215 intermediate filament binding 1/102 11/18639 0.0909090909090909 16.6122994652406 0.0585913089037691 0.304011508462953 GO:0097493 structural molecule activity conferring elasticity 1/102 11/18639 0.0909090909090909 16.6122994652406 0.0585913089037691 0.304011508462953 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/102 11/18639 0.0909090909090909 16.6122994652406 0.0585913089037691 0.304011508462953 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/102 11/18639 0.0909090909090909 16.6122994652406 0.0585913089037691 0.304011508462953 GO:0019003 GDP binding 2/102 75/18639 0.0266666666666667 4.87294117647059 0.063601126709649 0.307547035312423 GO:0044183 protein folding chaperone 2/102 75/18639 0.0266666666666667 4.87294117647059 0.063601126709649 0.307547035312423 GO:0004859 phospholipase inhibitor activity 1/102 12/18639 0.0833333333333333 15.2279411764706 0.0637461127738477 0.307547035312423 GO:0005049 nuclear export signal receptor activity 1/102 12/18639 0.0833333333333333 15.2279411764706 0.0637461127738477 0.307547035312423 GO:0008191 metalloendopeptidase inhibitor activity 1/102 14/18639 0.0714285714285714 13.0525210084034 0.0739720188784219 0.330430418482005 GO:0008474 palmitoyl-(protein) hydrolase activity 1/102 14/18639 0.0714285714285714 13.0525210084034 0.0739720188784219 0.330430418482005 GO:0098599 palmitoyl hydrolase activity 1/102 14/18639 0.0714285714285714 13.0525210084034 0.0739720188784219 0.330430418482005 GO:0008135 translation factor activity, RNA binding 2/102 83/18639 0.0240963855421687 4.40326009922041 0.0758607904126034 0.330430418482005 GO:0180051 translation factor activity 2/102 84/18639 0.0238095238095238 4.35084033613445 0.0774426265141146 0.330430418482005 GO:0004129 cytochrome-c oxidase activity 1/102 15/18639 0.0666666666666667 12.1823529411765 0.0790434204394636 0.330430418482005 GO:0047372 monoacylglycerol lipase activity 1/102 15/18639 0.0666666666666667 12.1823529411765 0.0790434204394636 0.330430418482005 GO:0015078 proton transmembrane transporter activity 3/102 185/18639 0.0162162162162162 2.96327503974563 0.081165715479483 0.330430418482005 GO:0004708 MAP kinase kinase activity 1/102 16/18639 0.0625 11.4209558823529 0.0840873192321596 0.330430418482005 GO:0008142 oxysterol binding 1/102 16/18639 0.0625 11.4209558823529 0.0840873192321596 0.330430418482005 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/102 16/18639 0.0625 11.4209558823529 0.0840873192321596 0.330430418482005 GO:0055102 lipase inhibitor activity 1/102 16/18639 0.0625 11.4209558823529 0.0840873192321596 0.330430418482005 GO:0031625 ubiquitin protein ligase binding 4/102 302/18639 0.0132450331125828 2.42033502142579 0.0841095610681467 0.330430418482005 GO:0072341 modified amino acid binding 2/102 91/18639 0.021978021978022 4.01616031027796 0.0887987333942601 0.335665237096108 GO:0008429 phosphatidylethanolamine binding 1/102 17/18639 0.0588235294117647 10.7491349480969 0.0891038629382395 0.335665237096108 GO:0045236 CXCR chemokine receptor binding 1/102 17/18639 0.0588235294117647 10.7491349480969 0.0891038629382395 0.335665237096108 GO:0043178 alcohol binding 2/102 92/18639 0.0217391304347826 3.97250639386189 0.0904596428502039 0.336047137336827 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/102 18/18639 0.0555555555555556 10.1519607843137 0.0940931984543116 0.336047137336827 GO:0050811 GABA receptor binding 1/102 18/18639 0.0555555555555556 10.1519607843137 0.0940931984543116 0.336047137336827 GO:0098641 cadherin binding involved in cell-cell adhesion 1/102 18/18639 0.0555555555555556 10.1519607843137 0.0940931984543116 0.336047137336827 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/102 19/18639 0.0526315789473684 9.61764705882353 0.0990554718959992 0.347075862071838 GO:0044389 ubiquitin-like protein ligase binding 4/102 322/18639 0.0124223602484472 2.27000365363537 0.100463178617904 0.347075862071838 GO:0001846 opsonin binding 1/102 21/18639 0.0476190476190476 8.70168067226891 0.108899413138412 0.347075862071838 GO:0036122 BMP binding 1/102 21/18639 0.0476190476190476 8.70168067226891 0.108899413138412 0.347075862071838 GO:0072542 protein phosphatase activator activity 1/102 21/18639 0.0476190476190476 8.70168067226891 0.108899413138412 0.347075862071838 GO:1904047 S-adenosyl-L-methionine binding 1/102 21/18639 0.0476190476190476 8.70168067226891 0.108899413138412 0.347075862071838 GO:0008649 rRNA methyltransferase activity 1/102 22/18639 0.0454545454545455 8.30614973262032 0.113781369302334 0.347075862071838 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/102 22/18639 0.0454545454545455 8.30614973262032 0.113781369302334 0.347075862071838 GO:0061133 endopeptidase activator activity 1/102 22/18639 0.0454545454545455 8.30614973262032 0.113781369302334 0.347075862071838 GO:0008013 beta-catenin binding 2/102 106/18639 0.0188679245283019 3.44783573806881 0.114612630076059 0.347075862071838 GO:0005496 steroid binding 2/102 108/18639 0.0185185185185185 3.38398692810457 0.118187606061355 0.347075862071838 GO:0003887 DNA-directed DNA polymerase activity 1/102 23/18639 0.0434782608695652 7.94501278772378 0.118636840126374 0.347075862071838 GO:0005212 structural constituent of eye lens 1/102 23/18639 0.0434782608695652 7.94501278772378 0.118636840126374 0.347075862071838 GO:0016917 GABA receptor activity 1/102 23/18639 0.0434782608695652 7.94501278772378 0.118636840126374 0.347075862071838 GO:0017134 fibroblast growth factor binding 1/102 23/18639 0.0434782608695652 7.94501278772378 0.118636840126374 0.347075862071838 GO:0099186 structural constituent of postsynapse 1/102 23/18639 0.0434782608695652 7.94501278772378 0.118636840126374 0.347075862071838 GO:0140102 catalytic activity, acting on a rRNA 1/102 23/18639 0.0434782608695652 7.94501278772378 0.118636840126374 0.347075862071838 GO:0004622 lysophospholipase activity 1/102 24/18639 0.0416666666666667 7.61397058823529 0.12346596788245 0.350032383171894 GO:0005540 hyaluronic acid binding 1/102 24/18639 0.0416666666666667 7.61397058823529 0.12346596788245 0.350032383171894 GO:0050431 transforming growth factor beta binding 1/102 24/18639 0.0416666666666667 7.61397058823529 0.12346596788245 0.350032383171894 GO:0001848 complement binding 1/102 25/18639 0.04 7.30941176470588 0.128268894085834 0.351803690983298 GO:0019211 phosphatase activator activity 1/102 25/18639 0.04 7.30941176470588 0.128268894085834 0.351803690983298 GO:0017124 SH3 domain binding 2/102 115/18639 0.0173913043478261 3.17800511508951 0.130913357783922 0.351803690983298 GO:0009055 electron transfer activity 2/102 116/18639 0.0172413793103448 3.15060851926978 0.132756747501961 0.351803690983298 GO:0005112 Notch binding 1/102 26/18639 0.0384615384615385 7.02828054298643 0.133045759499138 0.351803690983298 GO:0019865 immunoglobulin binding 1/102 26/18639 0.0384615384615385 7.02828054298643 0.133045759499138 0.351803690983298 GO:0050681 nuclear androgen receptor binding 1/102 26/18639 0.0384615384615385 7.02828054298643 0.133045759499138 0.351803690983298 GO:0022853 active monoatomic ion transmembrane transporter activity 2/102 118/18639 0.0169491525423729 3.09720837487537 0.136461381103905 0.354150407826882 GO:0005125 cytokine activity 3/102 234/18639 0.0128205128205128 2.34276018099548 0.136928226445691 0.354150407826882 GO:0015252 proton channel activity 1/102 27/18639 0.037037037037037 6.76797385620915 0.137796704136278 0.354150407826882 GO:0051082 unfolded protein binding 2/102 121/18639 0.0165289256198347 3.02041808458921 0.142061198976647 0.361729904801647 GO:0003785 actin monomer binding 1/102 29/18639 0.0344827586206897 6.30121703853955 0.147221387417874 0.368053468544686 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/102 29/18639 0.0344827586206897 6.30121703853955 0.147221387417874 0.368053468544686 GO:0051721 protein phosphatase 2A binding 1/102 30/18639 0.0333333333333333 6.09117647058823 0.151895402382054 0.372765845287512 GO:0098918 structural constituent of synapse 1/102 30/18639 0.0333333333333333 6.09117647058823 0.151895402382054 0.372765845287512 GO:0005525 GTP binding 4/102 378/18639 0.0105820105820106 1.93370681605976 0.15317287460905 0.372765845287512 GO:0051059 NF-kappaB binding 1/102 32/18639 0.03125 5.71047794117647 0.161167464252757 0.385400457995722 GO:0140142 nucleocytoplasmic carrier activity 1/102 32/18639 0.03125 5.71047794117647 0.161167464252757 0.385400457995722 GO:0140311 protein sequestering activity 1/102 33/18639 0.0303030303030303 5.53743315508021 0.165765783092237 0.39297922715832 GO:0008376 acetylgalactosaminyltransferase activity 1/102 34/18639 0.0294117647058824 5.37456747404844 0.170339140618014 0.39697681076232 GO:0051427 hormone receptor binding 1/102 34/18639 0.0294117647058824 5.37456747404844 0.170339140618014 0.39697681076232 GO:0034061 DNA polymerase activity 1/102 35/18639 0.0285714285714286 5.22100840336134 0.174887670994631 0.397374199260254 GO:0043015 gamma-tubulin binding 1/102 35/18639 0.0285714285714286 5.22100840336134 0.174887670994631 0.397374199260254 GO:0019001 guanyl nucleotide binding 4/102 400/18639 0.01 1.82735294117647 0.176289644762731 0.397374199260254 GO:0032561 guanyl ribonucleotide binding 4/102 400/18639 0.01 1.82735294117647 0.176289644762731 0.397374199260254 GO:0019903 protein phosphatase binding 2/102 144/18639 0.0138888888888889 2.53799019607843 0.186394491159592 0.41115911350623 GO:0019955 cytokine binding 2/102 144/18639 0.0138888888888889 2.53799019607843 0.186394491159592 0.41115911350623 GO:0005501 retinoid binding 1/102 38/18639 0.0263157894736842 4.80882352941176 0.188385630188309 0.41115911350623 GO:0019840 isoprenoid binding 1/102 38/18639 0.0263157894736842 4.80882352941176 0.188385630188309 0.41115911350623 GO:0005126 cytokine receptor binding 3/102 275/18639 0.0109090909090909 1.99347593582888 0.191097601590542 0.413794019192119 GO:0001530 lipopolysaccharide binding 1/102 41/18639 0.024390243902439 4.45695839311334 0.201664906851338 0.426029471278198 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/102 41/18639 0.024390243902439 4.45695839311334 0.201664906851338 0.426029471278198 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/102 41/18639 0.024390243902439 4.45695839311334 0.201664906851338 0.426029471278198 GO:0035198 miRNA binding 1/102 42/18639 0.0238095238095238 4.35084033613445 0.206043344290911 0.426029471278198 GO:0042056 chemoattractant activity 1/102 42/18639 0.0238095238095238 4.35084033613445 0.206043344290911 0.426029471278198 GO:0048487 beta-tubulin binding 1/102 42/18639 0.0238095238095238 4.35084033613445 0.206043344290911 0.426029471278198 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/102 43/18639 0.0232558139534884 4.24965800273598 0.210398002509028 0.431025383788893 GO:0001223 transcription coactivator binding 1/102 44/18639 0.0227272727272727 4.15307486631016 0.214729009378467 0.431025383788893 GO:0003954 NADH dehydrogenase activity 1/102 44/18639 0.0227272727272727 4.15307486631016 0.214729009378467 0.431025383788893 GO:0016790 thiolester hydrolase activity 1/102 44/18639 0.0227272727272727 4.15307486631016 0.214729009378467 0.431025383788893 GO:0008009 chemokine activity 1/102 45/18639 0.0222222222222222 4.06078431372549 0.219036492091206 0.433345577878285 GO:0051539 4 iron, 4 sulfur cluster binding 1/102 45/18639 0.0222222222222222 4.06078431372549 0.219036492091206 0.433345577878285 GO:0005504 fatty acid binding 1/102 47/18639 0.0212765957446809 3.88798498122653 0.227581390432039 0.447034874062933 GO:0015399 primary active transmembrane transporter activity 2/102 166/18639 0.0120481927710843 2.20163004961021 0.230343656615748 0.449251812548445 GO:0001222 transcription corepressor binding 1/102 49/18639 0.0204081632653061 3.72929171668667 0.236033701587324 0.457107520679678 GO:0043021 ribonucleoprotein complex binding 2/102 177/18639 0.0112994350282486 2.06480558325025 0.252596351691878 0.482519058830844 GO:0016860 intramolecular oxidoreductase activity 1/102 53/18639 0.0188679245283019 3.44783573806881 0.252664525351424 0.482519058830844 GO:0015485 cholesterol binding 1/102 54/18639 0.0185185185185185 3.38398692810457 0.256765903723002 0.483634407697436 GO:0140463 chromatin-protein adaptor activity 1/102 54/18639 0.0185185185185185 3.38398692810457 0.256765903723002 0.483634407697436 GO:0098632 cell-cell adhesion mediator activity 1/102 55/18639 0.0181818181818182 3.32245989304813 0.260844993194094 0.487975327403918 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/102 56/18639 0.0178571428571429 3.26313025210084 0.26490191370067 0.492216393700569 GO:0003924 GTPase activity 3/102 331/18639 0.00906344410876133 1.65621112493336 0.2718066442943 0.494537234337313 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/102 58/18639 0.0172413793103448 3.15060851926978 0.272949724372753 0.494537234337313 GO:0061980 regulatory RNA binding 1/102 58/18639 0.0172413793103448 3.15060851926978 0.272949724372753 0.494537234337313 GO:0045296 cadherin binding 3/102 334/18639 0.00898203592814371 1.64133497710461 0.276258776263809 0.494537234337313 GO:0036002 pre-mRNA binding 1/102 59/18639 0.0169491525423729 3.09720837487537 0.276940851228895 0.494537234337313 GO:0070888 E-box binding 1/102 59/18639 0.0169491525423729 3.09720837487537 0.276940851228895 0.494537234337313 GO:0019902 phosphatase binding 2/102 190/18639 0.0105263157894737 1.92352941176471 0.278963621871104 0.494935458158411 GO:0005543 phospholipid binding 4/102 497/18639 0.00804828973843058 1.47070659249615 0.28922737762257 0.509855954142352 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/102 349/18639 0.00859598853868195 1.57079049384797 0.29862214999248 0.523064275464535 GO:0008173 RNA methyltransferase activity 1/102 67/18639 0.0149253731343284 2.72739244951712 0.308098556404025 0.532585459774309 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/102 67/18639 0.0149253731343284 2.72739244951712 0.308098556404025 0.532585459774309 GO:1990841 promoter-specific chromatin binding 1/102 68/18639 0.0147058823529412 2.68728373702422 0.311898575101354 0.532585459774309 GO:0005516 calmodulin binding 2/102 207/18639 0.00966183574879227 1.76555839727195 0.313345880289641 0.532585459774309 GO:0002039 p53 binding 1/102 69/18639 0.0144927536231884 2.64833759590793 0.315677927066227 0.532585459774309 GO:0098960 postsynaptic neurotransmitter receptor activity 1/102 69/18639 0.0144927536231884 2.64833759590793 0.315677927066227 0.532585459774309 GO:0097110 scaffold protein binding 1/102 70/18639 0.0142857142857143 2.61050420168067 0.319436723589611 0.53564084748258 GO:0042379 chemokine receptor binding 1/102 72/18639 0.0138888888888889 2.53799019607843 0.326893092512189 0.544821820853649 GO:0003725 double-stranded RNA binding 1/102 75/18639 0.0133333333333333 2.43647058823529 0.337926228408848 0.559107732177212 GO:0051536 iron-sulfur cluster binding 1/102 76/18639 0.0131578947368421 2.40441176470588 0.341563996384624 0.559107732177212 GO:0098631 cell adhesion mediator activity 1/102 76/18639 0.0131578947368421 2.40441176470588 0.341563996384624 0.559107732177212 GO:0051540 metal cluster binding 1/102 77/18639 0.012987012987013 2.37318563789152 0.345181971516271 0.56168664004127 GO:0033293 monocarboxylic acid binding 1/102 79/18639 0.0126582278481013 2.31310498883098 0.352358969202391 0.562514401791913 GO:0046332 SMAD binding 1/102 79/18639 0.0126582278481013 2.31310498883098 0.352358969202391 0.562514401791913 GO:0015631 tubulin binding 3/102 385/18639 0.00779220779220779 1.42391138273491 0.352581387265105 0.562514401791913 GO:0000049 tRNA binding 1/102 80/18639 0.0125 2.28419117647059 0.355918203315611 0.562514401791913 GO:0048306 calcium-dependent protein binding 1/102 80/18639 0.0125 2.28419117647059 0.355918203315611 0.562514401791913 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/102 86/18639 0.0116279069767442 2.12482900136799 0.376870477522951 0.592225036107494 GO:0004175 endopeptidase activity 3/102 405/18639 0.00740740740740741 1.35359477124183 0.382433201574987 0.596149449562911 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/102 88/18639 0.0113636363636364 2.07653743315508 0.383703463900492 0.596149449562911 GO:0016410 N-acyltransferase activity 1/102 94/18639 0.0106382978723404 1.94399249061327 0.403760399074684 0.620302289081219 GO:0042562 hormone binding 1/102 94/18639 0.0106382978723404 1.94399249061327 0.403760399074684 0.620302289081219 GO:0004896 cytokine receptor activity 1/102 96/18639 0.0104166666666667 1.90349264705882 0.410301334179083 0.626849260551376 GO:0030594 neurotransmitter receptor activity 1/102 97/18639 0.0103092783505155 1.88386901152213 0.41354510616386 0.62831438781802 GO:0008170 N-methyltransferase activity 1/102 98/18639 0.0102040816326531 1.86464585834334 0.416771209020687 0.629736716926863 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/102 268/18639 0.00746268656716418 1.36369622475856 0.432500618835982 0.649932623933852 GO:0005096 GTPase activator activity 2/102 271/18639 0.00738007380073801 1.3485999565878 0.438101204941945 0.65142814497739 GO:0003779 actin binding 3/102 443/18639 0.00677200902934537 1.23748506174479 0.438233479348426 0.65142814497739 GO:0001217 DNA-binding transcription repressor activity 2/102 278/18639 0.00719424460431655 1.31464240372408 0.451053483722712 0.663410401044061 GO:0004620 phospholipase activity 1/102 109/18639 0.00917431192660551 1.67647058823529 0.451119072709962 0.663410401044061 GO:0004222 metalloendopeptidase activity 1/102 110/18639 0.00909090909090909 1.66122994652406 0.454140435612476 0.664301169113994 GO:1902936 phosphatidylinositol bisphosphate binding 1/102 111/18639 0.00900900900900901 1.64626391096979 0.457145329323282 0.665158547957156 GO:0031267 small GTPase binding 2/102 283/18639 0.00706713780918728 1.29141550613178 0.460203044048973 0.666083353228777 GO:0001221 transcription coregulator binding 1/102 115/18639 0.00869565217391304 1.58900255754476 0.469001982902305 0.675264635068764 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/102 122/18639 0.00819672131147541 1.49783027965284 0.489137279094724 0.700587248703381 GO:0140297 DNA-binding transcription factor binding 3/102 488/18639 0.00614754098360656 1.12337270973963 0.501767052234144 0.706466145119373 GO:0030695 GTPase regulator activity 3/102 489/18639 0.00613496932515337 1.12107542403464 0.503139428886534 0.706466145119373 GO:0060589 nucleoside-triphosphatase regulator activity 3/102 490/18639 0.00612244897959184 1.118787515006 0.504509925149782 0.706466145119373 GO:0031490 chromatin DNA binding 1/102 128/18639 0.0078125 1.42761948529412 0.505793056514783 0.706466145119373 GO:0035591 signaling adaptor activity 1/102 129/18639 0.00775193798449612 1.41655266757866 0.50851625397767 0.706466145119373 GO:0016298 lipase activity 1/102 130/18639 0.00769230769230769 1.40565610859729 0.511224592286383 0.706466145119373 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/102 130/18639 0.00769230769230769 1.40565610859729 0.511224592286383 0.706466145119373 GO:0051020 GTPase binding 2/102 315/18639 0.00634920634920635 1.16022408963585 0.51661017359956 0.710338988699395 GO:0051087 protein-folding chaperone binding 1/102 134/18639 0.00746268656716418 1.36369622475856 0.5219109531657 0.714057274231679 GO:0002020 protease binding 1/102 136/18639 0.00735294117647059 1.34364186851211 0.527167045687329 0.714142549576431 GO:0016779 nucleotidyltransferase activity 1/102 136/18639 0.00735294117647059 1.34364186851211 0.527167045687329 0.714142549576431 GO:0016922 nuclear receptor binding 1/102 137/18639 0.0072992700729927 1.33383426363246 0.529773593887075 0.714155579994831 GO:0140767 enzyme-substrate adaptor activity 1/102 139/18639 0.00719424460431655 1.31464240372408 0.534944080776944 0.717607913237364 GO:0008194 UDP-glycosyltransferase activity 1/102 145/18639 0.00689655172413793 1.26024340770791 0.550120151184497 0.734383696969596 GO:0019209 kinase activator activity 1/102 148/18639 0.00675675675675676 1.23469793322735 0.557523240709897 0.740670971957593 GO:0005506 iron ion binding 1/102 154/18639 0.00649350649350649 1.18659281894576 0.571969422233755 0.75620957266482 GO:0140375 immune receptor activity 1/102 156/18639 0.00641025641025641 1.17138009049774 0.576680251357423 0.758789804417661 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/102 167/18639 0.00598802395209581 1.09422331806974 0.601686760292415 0.78418890559438 GO:0016874 ligase activity 1/102 167/18639 0.00598802395209581 1.09422331806974 0.601686760292415 0.78418890559438 GO:0003823 antigen binding 1/102 174/18639 0.00574712643678161 1.05020283975659 0.61683250915914 0.80013650952247 GO:0004252 serine-type endopeptidase activity 1/102 176/18639 0.00568181818181818 1.03826871657754 0.621054138165238 0.801830460072491 GO:0005319 lipid transporter activity 1/102 178/18639 0.00561797752808989 1.02660277594184 0.625229705507281 0.802767384110349 GO:0016853 isomerase activity 1/102 180/18639 0.00555555555555556 1.01519607843137 0.62935970883613 0.802767384110349 GO:0008237 metallopeptidase activity 1/102 184/18639 0.00543478260869565 0.993126598465473 0.637484987496884 0.802767384110349 GO:1901981 phosphatidylinositol phosphate binding 1/102 185/18639 0.00540540540540541 0.987758346581876 0.639488592551087 0.802767384110349 GO:0031406 carboxylic acid binding 1/102 187/18639 0.0053475935828877 0.977194086190626 0.643462964484284 0.802767384110349 GO:0043177 organic acid binding 1/102 189/18639 0.00529100529100529 0.966853408029879 0.647393946764257 0.802767384110349 GO:0008236 serine-type peptidase activity 1/102 194/18639 0.00515463917525773 0.941934505761067 0.657034638602811 0.802767384110349 GO:0016758 hexosyltransferase activity 1/102 197/18639 0.0050761421319797 0.92759032547029 0.662693285584502 0.802767384110349 GO:0017171 serine hydrolase activity 1/102 198/18639 0.00505050505050505 0.922905525846702 0.664558879601982 0.802767384110349 GO:0016887 ATP hydrolysis activity 2/102 417/18639 0.00479616306954436 0.876428269149386 0.669160010739951 0.802767384110349 GO:0003714 transcription corepressor activity 1/102 204/18639 0.00490196078431373 0.89576124567474 0.675539800555462 0.802767384110349 GO:0008168 methyltransferase activity 1/102 204/18639 0.00490196078431373 0.89576124567474 0.675539800555462 0.802767384110349 GO:0051015 actin filament binding 1/102 209/18639 0.00478468899521531 0.874331550802139 0.684418088518855 0.802767384110349 GO:0016741 transferase activity, transferring one-carbon groups 1/102 215/18639 0.00465116279069767 0.849931600547196 0.694754984678105 0.802767384110349 GO:0022804 active transmembrane transporter activity 2/102 457/18639 0.00437636761487965 0.799716823271978 0.717536025636918 0.802767384110349 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/102 229/18639 0.00436681222707424 0.797970716670948 0.717588754037748 0.802767384110349 GO:0005085 guanyl-nucleotide exchange factor activity 1/102 230/18639 0.00434782608695652 0.794501278772379 0.719153444265241 0.802767384110349 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/102 243/18639 0.00411522633744856 0.75199709513435 0.738729946311628 0.802767384110349 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0004711 ribosomal protein S6 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0035175 histone H3S10 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0035979 histone H2AXS139 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0044022 histone H3S28 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0044023 histone H4S1 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0044024 histone H2AS1 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0044025 histone H2BS14 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0072354 histone H3T3 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0072371 histone H2AS121 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0140823 histone H2BS36 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0140855 histone H3S57 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0140995 histone H2A kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0140997 histone H4 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0140998 histone H2B kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:1990244 histone H2AT120 kinase activity 1/102 245/18639 0.00408163265306122 0.745858343337335 0.741619311845424 0.802767384110349 GO:0004677 DNA-dependent protein kinase activity 1/102 246/18639 0.0040650406504065 0.742826398852224 0.74305210678898 0.802767384110349 GO:0140857 histone H3T45 kinase activity 1/102 246/18639 0.0040650406504065 0.742826398852224 0.74305210678898 0.802767384110349 GO:0035402 histone H3T11 kinase activity 1/102 247/18639 0.00404858299595142 0.739819004524887 0.744477033941023 0.802767384110349 GO:0035403 histone H3T6 kinase activity 1/102 247/18639 0.00404858299595142 0.739819004524887 0.744477033941023 0.802767384110349 GO:0004679 AMP-activated protein kinase activity 1/102 248/18639 0.00403225806451613 0.736835863377609 0.745894136079889 0.802767384110349 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 2/102 484/18639 0.00413223140495868 0.755104521147302 0.746762215304259 0.802767384110349 GO:0042277 peptide binding 1/102 249/18639 0.00401606425702811 0.733876683203402 0.747303455753634 0.802767384110349 GO:0140104 molecular carrier activity 1/102 249/18639 0.00401606425702811 0.733876683203402 0.747303455753634 0.802767384110349 GO:0001216 DNA-binding transcription activator activity 2/102 491/18639 0.00407331975560081 0.744339283574937 0.753908636820822 0.804735762685139 GO:0003713 transcription coactivator activity 1/102 256/18639 0.00390625 0.713809742647059 0.756954310688722 0.804735762685139 GO:0003712 transcription coregulator activity 2/102 495/18639 0.00404040404040404 0.738324420677362 0.757914772856186 0.804735762685139 GO:0016757 glycosyltransferase activity 1/102 267/18639 0.00374531835205993 0.684401850627892 0.771387566751187 0.815890695602217 GO:0008017 microtubule binding 1/102 276/18639 0.0036231884057971 0.662084398976982 0.782562678770594 0.824539220926871 GO:0035091 phosphatidylinositol binding 1/102 284/18639 0.00352112676056338 0.643434134217067 0.792040977622475 0.831340720786949 GO:0019207 kinase regulator activity 1/102 287/18639 0.00348432055749129 0.636708341873335 0.795488862017034 0.83178493176686 GO:0001664 G protein-coupled receptor binding 1/102 297/18639 0.00336700336700337 0.615270350564468 0.80657807831557 0.840185498245386 GO:0140097 catalytic activity, acting on DNA 1/102 336/18639 0.00297619047619048 0.543855042016807 0.844419525297725 0.876284413044809 GO:0005261 monoatomic cation channel activity 1/102 341/18639 0.00293255131964809 0.535880627910988 0.84870707753264 0.877422730531864 GO:0141003 histone H2AX kinase activity 1/102 354/18639 0.00282485875706215 0.516201395812562 0.859314870933129 0.877481555641466 GO:0045182 translation regulator activity 1/102 356/18639 0.00280898876404494 0.513301387970919 0.860880115571656 0.877481555641466 GO:0140996 histone H3 kinase activity 1/102 357/18639 0.00280112044817927 0.511863568956995 0.861656258885756 0.877481555641466 GO:0035173 histone kinase activity 1/102 360/18639 0.00277777777777778 0.507598039215686 0.863959055421601 0.877481555641466 GO:0106310 protein serine kinase activity 1/102 361/18639 0.00277008310249307 0.506191950464396 0.864718187559409 0.877481555641466 GO:0140098 catalytic activity, acting on RNA 1/102 387/18639 0.00258397932816537 0.47218422252622 0.883048255453927 0.892787758271434 GO:0004674 protein serine/threonine kinase activity 1/102 433/18639 0.0023094688221709 0.422021464474935 0.909653390454416 0.916317517857013 GO:0005216 monoatomic ion channel activity 1/102 448/18639 0.00223214285714286 0.407891281512605 0.916958004213171 0.920304566272343 GO:0016755 aminoacyltransferase activity 1/102 496/18639 0.00201612903225806 0.368417931688805 0.936623400201339 0.936623400201339