ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 72/3030 175/18639 0.411428571428571 2.53089674681754 3.16715521565739e-15 3.92727246741516e-12 GO:0003712 transcription coregulator activity 137/3030 495/18639 0.276767676767677 1.70253225322532 5.6897853828327e-11 3.52766693735627e-08 GO:0019843 rRNA binding 32/3030 65/18639 0.492307692307692 3.02842345773039 6.62931447510579e-10 2.74011664971039e-07 GO:0003713 transcription coactivator activity 80/3030 256/18639 0.3125 1.92233910891089 1.62090116015573e-09 5.02479359648275e-07 GO:0042393 histone binding 76/3030 247/18639 0.307692307692308 1.89276466108149 8.77894883375626e-09 2.17717931077155e-06 GO:0043021 ribonucleoprotein complex binding 57/3030 177/18639 0.322033898305085 1.98098674274207 1.10594599544792e-07 2.2856217239257e-05 GO:0045296 cadherin binding 91/3030 334/18639 0.272455089820359 1.67600343866722 2.06078764460491e-07 3.65053811330013e-05 GO:0140097 catalytic activity, acting on DNA 90/3030 336/18639 0.267857142857143 1.64771923620934 5.41062146542023e-07 8.38646327140136e-05 GO:0140030 modification-dependent protein binding 54/3030 173/18639 0.312138728323699 1.92011675155955 7.20781080486714e-07 9.9307615533725e-05 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 92/3030 349/18639 0.263610315186246 1.62159493886351 8.69387875014685e-07 0.000107804096501821 GO:0008094 ATP-dependent activity, acting on DNA 62/3030 210/18639 0.295238095238095 1.81615275813296 9.77968425737998e-07 0.000110243713446829 GO:0140297 DNA-binding transcription factor binding 120/3030 488/18639 0.245901639344262 1.51266028242168 1.09015940427925e-06 0.000112649805108856 GO:0140098 catalytic activity, acting on RNA 98/3030 387/18639 0.253229974160207 1.55774042520531 2.69937216912338e-06 0.000246367473062145 GO:0008135 translation factor activity, RNA binding 31/3030 83/18639 0.373493975903614 2.29754264583085 2.78156824425003e-06 0.000246367473062145 GO:0180051 translation factor activity 31/3030 84/18639 0.369047619047619 2.2701909476662 3.72717576631326e-06 0.000308113196681897 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 64/3030 229/18639 0.279475982532751 1.71919235591681 5.09834342210723e-06 0.000395121615213311 GO:0016922 nuclear receptor binding 43/3030 137/18639 0.313868613138686 1.93075811230758 8.00620099347776e-06 0.000577764679397653 GO:0003725 double-stranded RNA binding 28/3030 75/18639 0.373333333333333 2.29655445544554 8.39048393730048e-06 0.000577764679397653 GO:0001098 basal transcription machinery binding 24/3030 60/18639 0.4 2.46059405940594 9.31878515157505e-06 0.000577764679397653 GO:0001099 basal RNA polymerase II transcription machinery binding 24/3030 60/18639 0.4 2.46059405940594 9.31878515157505e-06 0.000577764679397653 GO:0000339 RNA cap binding 12/3030 20/18639 0.6 3.69089108910891 1.15866110518458e-05 0.000684161795442324 GO:0140658 ATP-dependent chromatin remodeler activity 47/3030 158/18639 0.29746835443038 1.82987216443163 1.53763751654954e-05 0.000866668418418832 GO:0031491 nucleosome binding 27/3030 74/18639 0.364864864864865 2.24446079743109 1.96632561579588e-05 0.00106010598416821 GO:0070063 RNA polymerase binding 23/3030 59/18639 0.389830508474576 2.39803658331935 2.33819702434247e-05 0.0011479972765769 GO:0031625 ubiquitin protein ligase binding 77/3030 302/18639 0.254966887417219 1.56842502131008 2.35752767659808e-05 0.0011479972765769 GO:0140104 molecular carrier activity 66/3030 249/18639 0.265060240963855 1.63051413575092 2.40709106379028e-05 0.0011479972765769 GO:0016407 acetyltransferase activity 32/3030 96/18639 0.333333333333333 2.05049504950495 2.95455056477698e-05 0.0013569047038235 GO:0044389 ubiquitin-like protein ligase binding 80/3030 322/18639 0.248447204968944 1.52831929155648 4.3984076105521e-05 0.00194786622753021 GO:0030515 snoRNA binding 15/3030 32/18639 0.46875 2.88350866336634 4.98474463529745e-05 0.00209591720259677 GO:0140597 protein carrier chaperone 52/3030 188/18639 0.276595744680851 1.70147461554666 5.07076742563736e-05 0.00209591720259677 GO:0051087 protein-folding chaperone binding 40/3030 134/18639 0.298507462686567 1.83626422343727 5.87070553896321e-05 0.00234828221558528 GO:0050681 nuclear androgen receptor binding 13/3030 26/18639 0.5 3.07574257425743 6.85890840000452e-05 0.00259378733723049 GO:0061775 cohesin loader activity 44/3030 153/18639 0.287581699346405 1.76905455251407 6.92013863609557e-05 0.00259378733723049 GO:0003743 translation initiation factor activity 20/3030 51/18639 0.392156862745098 2.41234711706465 7.11199753756748e-05 0.00259378733723049 GO:0140713 histone chaperone activity 46/3030 164/18639 0.280487804878049 1.72541656604685 9.30610747297741e-05 0.00329702093328343 GO:0004386 helicase activity 44/3030 155/18639 0.283870967741935 1.74622804215905 9.65493822939454e-05 0.00332558983456923 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 22/3030 60/18639 0.366666666666667 2.25554455445545 0.000103580825521332 0.00347135739585005 GO:0051020 GTPase binding 77/3030 315/18639 0.244444444444444 1.50369636963696 0.000106983033129105 0.00349102529158131 GO:0140674 ATP-dependent histone chaperone activity 43/3030 152/18639 0.282894736842105 1.74022277227723 0.000125451445915321 0.00398871263935893 GO:0000340 RNA 7-methylguanosine cap binding 8/3030 12/18639 0.666666666666667 4.1009900990099 0.000128780519517303 0.00399219610503638 GO:0043175 RNA polymerase core enzyme binding 17/3030 42/18639 0.404761904761905 2.48988684582744 0.00015500903209385 0.004688078043814 GO:0003689 DNA clamp loader activity 44/3030 160/18639 0.275 1.69165841584158 0.000212638336048917 0.00603571407916094 GO:0000510 H3-H4 histone complex chaperone activity 42/3030 151/18639 0.278145695364238 1.71100911415645 0.000223905522291454 0.00603571407916094 GO:0140584 chromatin extrusion motor activity 42/3030 151/18639 0.278145695364238 1.71100911415645 0.000223905522291454 0.00603571407916094 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 42/3030 151/18639 0.278145695364238 1.71100911415645 0.000223905522291454 0.00603571407916094 GO:0140849 ATP-dependent H2AZ histone chaperone activity 42/3030 151/18639 0.278145695364238 1.71100911415645 0.000223905522291454 0.00603571407916094 GO:0016853 isomerase activity 48/3030 180/18639 0.266666666666667 1.64039603960396 0.000249909901647128 0.00659336761792423 GO:0000993 RNA polymerase II complex binding 15/3030 36/18639 0.416666666666667 2.56311881188119 0.000256615412590068 0.00661747709429003 GO:0015616 DNA translocase activity 42/3030 152/18639 0.276315789473684 1.69975247524753 0.000261497078725977 0.00661747709429003 GO:0140666 annealing activity 8/3030 13/18639 0.615384615384615 3.78552932216299 0.000286967478486868 0.00711679346647432 GO:0016410 N-acyltransferase activity 29/3030 94/18639 0.308510638297872 1.8977986096482 0.000313858326708587 0.00763106519840486 GO:0002039 p53 binding 23/3030 69/18639 0.333333333333333 2.05049504950495 0.000373204211604403 0.00889948504595116 GO:0016877 ligase activity, forming carbon-sulfur bonds 16/3030 41/18639 0.390243902439024 2.40057957015214 0.000394918854295792 0.009239610930694 GO:0019787 ubiquitin-like protein transferase activity 106/3030 479/18639 0.221294363256785 1.36128898902416 0.000418638676976028 0.00961318443426434 GO:0031267 small GTPase binding 68/3030 283/18639 0.240282685512367 1.47809537137459 0.000439167516932747 0.0097791561692109 GO:0035064 methylated histone binding 24/3030 74/18639 0.324324324324324 1.9950762643832 0.000445208918098324 0.0097791561692109 GO:0016755 aminoacyltransferase activity 109/3030 496/18639 0.219758064516129 1.35183847013734 0.000457868558754318 0.0097791561692109 GO:0003714 transcription corepressor activity 52/3030 204/18639 0.254901960784314 1.56802562609202 0.000465298559664067 0.0097791561692109 GO:0008168 methyltransferase activity 52/3030 204/18639 0.254901960784314 1.56802562609202 0.000465298559664067 0.0097791561692109 GO:0106310 protein serine kinase activity 83/3030 361/18639 0.229916897506925 1.41433038040646 0.00050203075279954 0.0103753022245238 GO:0016741 transferase activity, transferring one-carbon groups 54/3030 215/18639 0.251162790697674 1.54502417683629 0.00053815003478525 0.010849017153849 GO:0140463 chromatin-protein adaptor activity 19/3030 54/18639 0.351851851851852 2.16441144114411 0.000550675816018179 0.010849017153849 GO:0001221 transcription coregulator binding 33/3030 115/18639 0.28695652173913 1.76520878174774 0.000551200065074586 0.010849017153849 GO:0030983 mismatched DNA binding 8/3030 14/18639 0.571428571428571 3.51513437057992 0.000574097842860092 0.0111231457054143 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 44/3030 167/18639 0.263473053892216 1.62075057805182 0.000583354685266672 0.011128612457395 GO:0140566 histone reader activity 14/3030 35/18639 0.4 2.46059405940594 0.000673399236623709 0.0126517432335364 GO:0140034 methylation-dependent protein binding 24/3030 76/18639 0.315789473684211 1.94257425742574 0.000687973623230954 0.0127326461612893 GO:0016887 ATP hydrolysis activity 93/3030 417/18639 0.223021582733813 1.37191395398533 0.000702021148724275 0.0128015621237956 GO:0043022 ribosome binding 32/3030 112/18639 0.285714285714286 1.75756718528996 0.000719857457221916 0.012836490052692 GO:0030544 Hsp70 protein binding 18/3030 51/18639 0.352941176470588 2.17111240535818 0.0007321577362769 0.012836490052692 GO:0048156 tau protein binding 16/3030 43/18639 0.372093023255814 2.28892470642413 0.000734992575597684 0.012836490052692 GO:0008276 protein methyltransferase activity 28/3030 95/18639 0.294736842105263 1.81306930693069 0.000886799215217958 0.0152726531509759 GO:0000287 magnesium ion binding 56/3030 230/18639 0.243478260869565 1.49775290572536 0.000960934406519327 0.0161904641688024 GO:0032451 demethylase activity 15/3030 40/18639 0.375 2.30680693069307 0.000972433605523292 0.0161904641688024 GO:0008080 N-acetyltransferase activity 22/3030 69/18639 0.318840579710145 1.96134309083082 0.000979261945693696 0.0161904641688024 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 35/3030 128/18639 0.2734375 1.68204672029703 0.00100022581212563 0.0163194737767866 GO:0004674 protein serine/threonine kinase activity 95/3030 433/18639 0.219399538106236 1.34963300025153 0.00108212738902175 0.0173145755489899 GO:0004842 ubiquitin-protein transferase activity 98/3030 449/18639 0.21826280623608 1.34264041103442 0.00108914265550097 0.0173145755489899 GO:0016504 peptidase activator activity 19/3030 57/18639 0.333333333333333 2.05049504950495 0.00117094940839787 0.0183794590685235 GO:0140296 general transcription initiation factor binding 18/3030 53/18639 0.339622641509434 2.08918363534467 0.0012249873378581 0.0186918041155141 GO:0004407 histone deacetylase activity 10/3030 22/18639 0.454545454545455 2.7961296129613 0.00123607091731625 0.0186918041155141 GO:0033558 protein lysine deacetylase activity 10/3030 22/18639 0.454545454545455 2.7961296129613 0.00123607091731625 0.0186918041155141 GO:0001222 transcription corepressor binding 17/3030 49/18639 0.346938775510204 2.13418872499495 0.00126867833898444 0.0189537486788037 GO:0008137 NADH dehydrogenase (ubiquinone) activity 15/3030 41/18639 0.365853658536585 2.25054334701763 0.00130561519276992 0.0192733671313655 GO:0044183 protein folding chaperone 23/3030 75/18639 0.306666666666667 1.88645544554455 0.00137531033731582 0.0200633508031955 GO:0015631 tubulin binding 85/3030 385/18639 0.220779220779221 1.35812009772406 0.00158525338508572 0.0228571418314685 GO:0048487 beta-tubulin binding 15/3030 42/18639 0.357142857142857 2.19695898161245 0.00172953715099848 0.0244584014511794 GO:0042162 telomeric DNA binding 14/3030 38/18639 0.368421052631579 2.26633663366337 0.00173575752234177 0.0244584014511794 GO:0016874 ligase activity 42/3030 167/18639 0.251497005988024 1.54708009723128 0.00204121704657025 0.0277622921109893 GO:0008641 ubiquitin-like modifier activating enzyme activity 6/3030 10/18639 0.6 3.69089108910891 0.00212694979882579 0.0277622921109893 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 6/3030 10/18639 0.6 3.69089108910891 0.00212694979882579 0.0277622921109893 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 6/3030 10/18639 0.6 3.69089108910891 0.00212694979882579 0.0277622921109893 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 6/3030 10/18639 0.6 3.69089108910891 0.00212694979882579 0.0277622921109893 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 6/3030 10/18639 0.6 3.69089108910891 0.00212694979882579 0.0277622921109893 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 6/3030 10/18639 0.6 3.69089108910891 0.00212694979882579 0.0277622921109893 GO:0010485 histone H4 acetyltransferase activity 13/3030 35/18639 0.371428571428571 2.28483734087694 0.00230888674185928 0.0298231204156824 GO:0031418 L-ascorbic acid binding 9/3030 20/18639 0.45 2.76816831683168 0.00236494853943001 0.0299238386621757 GO:0061608 nuclear import signal receptor activity 9/3030 20/18639 0.45 2.76816831683168 0.00236494853943001 0.0299238386621757 GO:0032182 ubiquitin-like protein binding 32/3030 120/18639 0.266666666666667 1.64039603960396 0.00248897568921673 0.031175049036654 GO:0003684 damaged DNA binding 22/3030 74/18639 0.297297297297297 1.82881990901793 0.00267616818964847 0.033184485551641 GO:0048027 mRNA 5'-UTR binding 10/3030 24/18639 0.416666666666667 2.56311881188119 0.00274435997777053 0.0336931324003511 GO:0003697 single-stranded DNA binding 32/3030 121/18639 0.264462809917355 1.62683904754112 0.00286664584978215 0.0348494201346065 GO:0003954 NADH dehydrogenase activity 15/3030 44/18639 0.340909090909091 2.09709720972097 0.00292424618225355 0.0350802978456592 GO:0046966 nuclear thyroid hormone receptor binding 11/3030 28/18639 0.392857142857143 2.41665487977369 0.00296987473483759 0.0350802978456592 GO:0031072 heat shock protein binding 34/3030 131/18639 0.259541984732824 1.59656866450004 0.00301327716991994 0.0350802978456592 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 14/3030 40/18639 0.35 2.1530198019802 0.00302709021732705 0.0350802978456592 GO:0140662 ATP-dependent protein folding chaperone 14/3030 40/18639 0.35 2.1530198019802 0.00302709021732705 0.0350802978456592 GO:0051059 NF-kappaB binding 12/3030 32/18639 0.375 2.30680693069307 0.00307281427959422 0.0352804602471929 GO:0035402 histone H3T11 kinase activity 57/3030 247/18639 0.230769230769231 1.41957349581112 0.00320945161168542 0.0365111926466965 GO:0042826 histone deacetylase binding 33/3030 127/18639 0.259842519685039 1.5984174007952 0.00337032424521048 0.0379927460369181 GO:0008174 mRNA methyltransferase activity 7/3030 14/18639 0.5 3.07574257425743 0.00353810384703834 0.0395247636966445 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 18/3030 58/18639 0.310344827586207 1.90908159781495 0.00379453629015985 0.0417197783868466 GO:0042054 histone methyltransferase activity 20/3030 67/18639 0.298507462686567 1.83626422343727 0.00388283102457083 0.0417197783868466 GO:0008139 nuclear localization sequence binding 10/3030 25/18639 0.4 2.46059405940594 0.00391532640852947 0.0417197783868466 GO:0061650 ubiquitin-like protein conjugating enzyme activity 14/3030 41/18639 0.341463414634146 2.10050712388312 0.00391970689672703 0.0417197783868466 GO:0140318 protein transporter activity 14/3030 41/18639 0.341463414634146 2.10050712388312 0.00391970689672703 0.0417197783868466 GO:0019107 myristoyltransferase activity 6/3030 11/18639 0.545454545454545 3.35535553555356 0.00403739790840451 0.0417197783868466 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 6/3030 11/18639 0.545454545454545 3.35535553555356 0.00403739790840451 0.0417197783868466 GO:0032404 mismatch repair complex binding 6/3030 11/18639 0.545454545454545 3.35535553555356 0.00403739790840451 0.0417197783868466 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 6/3030 11/18639 0.545454545454545 3.35535553555356 0.00403739790840451 0.0417197783868466 GO:0016417 S-acyltransferase activity 11/3030 29/18639 0.379310344827586 2.33332195288494 0.00409115796222578 0.0417273461890435 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 17/3030 54/18639 0.314814814814815 1.93657865786579 0.0041054324476317 0.0417273461890435 GO:0035591 signaling adaptor activity 33/3030 129/18639 0.255813953488372 1.57363573566659 0.0043796341526837 0.0441524093441283 GO:0003746 translation elongation factor activity 8/3030 18/18639 0.444444444444444 2.73399339933993 0.00453897227934851 0.0453897227934851 GO:0005525 GTP binding 81/3030 378/18639 0.214285714285714 1.31817538896747 0.0046453178613483 0.0460201691085943 GO:0030145 manganese ion binding 20/3030 68/18639 0.294117647058824 1.80926033779849 0.00467624299006684 0.0460201691085943 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 15/3030 46/18639 0.326086956521739 2.00591907016789 0.00472694124950591 0.0461528121999002 GO:0004402 histone acetyltransferase activity 14/3030 42/18639 0.333333333333333 2.05049504950495 0.00501479176959134 0.0479707281251497 GO:0016859 cis-trans isomerase activity 14/3030 42/18639 0.333333333333333 2.05049504950495 0.00501479176959134 0.0479707281251497 GO:0003924 GTPase activity 72/3030 331/18639 0.217522658610272 1.33808740390655 0.00502918923892698 0.0479707281251497 GO:0009055 electron transfer activity 30/3030 116/18639 0.258620689655172 1.59090133151246 0.00539898964388328 0.0499108597712258 GO:0005048 signal sequence binding 16/3030 51/18639 0.313725490196078 1.92987769365172 0.00548577075668386 0.0499108597712258 GO:0051082 unfolded protein binding 31/3030 121/18639 0.256198347107438 1.57600032730546 0.00549431562092437 0.0499108597712258 GO:0043995 histone H4K5 acetyltransferase activity 11/3030 30/18639 0.366666666666667 2.25554455445545 0.0055249538194278 0.0499108597712258 GO:0043996 histone H4K8 acetyltransferase activity 11/3030 30/18639 0.366666666666667 2.25554455445545 0.0055249538194278 0.0499108597712258 GO:0043997 histone H4K12 acetyltransferase activity 11/3030 30/18639 0.366666666666667 2.25554455445545 0.0055249538194278 0.0499108597712258 GO:0051721 protein phosphatase 2A binding 11/3030 30/18639 0.366666666666667 2.25554455445545 0.0055249538194278 0.0499108597712258 GO:0042809 nuclear vitamin D receptor binding 7/3030 15/18639 0.466666666666667 2.87069306930693 0.00571066057012776 0.0499108597712258 GO:0061578 K63-linked deubiquitinase activity 7/3030 15/18639 0.466666666666667 2.87069306930693 0.00571066057012776 0.0499108597712258 GO:0141050 histone H3K deacetylase activity 7/3030 15/18639 0.466666666666667 2.87069306930693 0.00571066057012776 0.0499108597712258 GO:0141051 histone H4K deacetylase activity 7/3030 15/18639 0.466666666666667 2.87069306930693 0.00571066057012776 0.0499108597712258 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 55/3030 243/18639 0.226337448559671 1.39231145336756 0.00571559845767263 0.0499108597712258 GO:0061733 protein-lysine-acetyltransferase activity 15/3030 47/18639 0.319148936170213 1.96323994101538 0.00591844132719862 0.0513207499701139 GO:0004197 cysteine-type endopeptidase activity 24/3030 88/18639 0.272727272727273 1.67767776777678 0.0059974053765122 0.0516443240755217 GO:0008186 ATP-dependent activity, acting on RNA 22/3030 79/18639 0.278481012658228 1.71307181351047 0.00637208636617792 0.0517292877242564 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 13/3030 39/18639 0.333333333333333 2.05049504950495 0.00674144218736627 0.0517292877242564 GO:0004676 3-phosphoinositide-dependent protein kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0004711 ribosomal protein S6 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0035175 histone H3S10 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0035979 histone H2AXS139 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0044022 histone H3S28 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0044023 histone H4S1 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0044024 histone H2AS1 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0044025 histone H2BS14 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0072354 histone H3T3 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0072371 histone H2AS121 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0072518 Rho-dependent protein serine/threonine kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0140823 histone H2BS36 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0140855 histone H3S57 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0140995 histone H2A kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0140997 histone H4 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0140998 histone H2B kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:1990244 histone H2AT120 kinase activity 55/3030 245/18639 0.224489795918367 1.38094564558497 0.00679989830568854 0.0517292877242564 GO:0035197 siRNA binding 6/3030 12/18639 0.5 3.07574257425743 0.00697130524610876 0.0520937577549298 GO:0141221 histone deacetylase activity, hydrolytic mechanism 6/3030 12/18639 0.5 3.07574257425743 0.00697130524610876 0.0520937577549298 GO:0003727 single-stranded RNA binding 24/3030 89/18639 0.269662921348315 1.65882745577929 0.00697384176396641 0.0520937577549298 GO:0061631 ubiquitin conjugating enzyme activity 12/3030 35/18639 0.342857142857143 2.10908062234795 0.00708314652624557 0.0525934233086497 GO:0008171 O-methyltransferase activity 9/3030 23/18639 0.391304347826087 2.40710288420146 0.0072539470574994 0.0529111432429368 GO:0042171 lysophosphatidic acid acyltransferase activity 9/3030 23/18639 0.391304347826087 2.40710288420146 0.0072539470574994 0.0529111432429368 GO:0071617 lysophospholipid acyltransferase activity 9/3030 23/18639 0.391304347826087 2.40710288420146 0.0072539470574994 0.0529111432429368 GO:0140457 protein demethylase activity 11/3030 31/18639 0.354838709677419 2.18278505269882 0.00732673339493803 0.0530715009739532 GO:0004677 DNA-dependent protein kinase activity 55/3030 246/18639 0.223577235772358 1.37533204539966 0.00740433037781767 0.0530715009739532 GO:0140857 histone H3T45 kinase activity 55/3030 246/18639 0.223577235772358 1.37533204539966 0.00740433037781767 0.0530715009739532 GO:0035403 histone H3T6 kinase activity 55/3030 247/18639 0.222672064777328 1.36976389946687 0.00805349799799175 0.0573927443535044 GO:0034212 protein N-acetyltransferase activity 16/3030 53/18639 0.30188679245283 1.85705212030637 0.00824211391919606 0.0584012643417321 GO:0043130 ubiquitin binding 26/3030 100/18639 0.26 1.59938613861386 0.00851410855871192 0.0597570282883563 GO:0015036 disulfide oxidoreductase activity 13/3030 40/18639 0.325 1.99923267326733 0.00852983387664441 0.0597570282883563 GO:0000062 fatty-acyl-CoA binding 7/3030 16/18639 0.4375 2.69127475247525 0.00874384869986338 0.060613914570055 GO:0004679 AMP-activated protein kinase activity 55/3030 248/18639 0.221774193548387 1.36424065793676 0.00874991186132245 0.060613914570055 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 12/3030 36/18639 0.333333333333333 2.05049504950495 0.00908302862147897 0.0618843708276589 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 12/3030 36/18639 0.333333333333333 2.05049504950495 0.00908302862147897 0.0618843708276589 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 12/3030 36/18639 0.333333333333333 2.05049504950495 0.00908302862147897 0.0618843708276589 GO:0022884 macromolecule transmembrane transporter activity 11/3030 32/18639 0.34375 2.11457301980198 0.00955497674107052 0.0643922345593883 GO:0140142 nucleocytoplasmic carrier activity 11/3030 32/18639 0.34375 2.11457301980198 0.00955497674107052 0.0643922345593883 GO:0140939 histone H4 methyltransferase activity 8/3030 20/18639 0.4 2.46059405940594 0.00964999242858716 0.0646810303321518 GO:0003724 RNA helicase activity 21/3030 77/18639 0.272727272727273 1.67767776777678 0.0097443692308433 0.0649624615389554 GO:0016866 intramolecular transferase activity 10/3030 28/18639 0.357142857142857 2.19695898161245 0.00987987544507652 0.0650001428348295 GO:0036408 histone H3K14 acetyltransferase activity 10/3030 28/18639 0.357142857142857 2.19695898161245 0.00987987544507652 0.0650001428348295 GO:0035035 histone acetyltransferase binding 9/3030 24/18639 0.375 2.30680693069307 0.00995969930533677 0.0650001428348295 GO:0140033 acetylation-dependent protein binding 9/3030 24/18639 0.375 2.30680693069307 0.00995969930533677 0.0650001428348295 GO:0140996 histone H3 kinase activity 75/3030 357/18639 0.210084033613445 1.2923288127132 0.010160616606469 0.0659642125236731 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 19/3030 68/18639 0.279411764705882 1.71879732090856 0.0103665844215913 0.0669508577227772 GO:0015605 organophosphate ester transmembrane transporter activity 15/3030 50/18639 0.3 1.84544554455446 0.0109944920415045 0.0706381872096661 GO:0009982 pseudouridine synthase activity 6/3030 13/18639 0.461538461538462 2.83914699162224 0.0111843375899598 0.0711209159566675 GO:0046975 histone H3K36 methyltransferase activity 6/3030 13/18639 0.461538461538462 2.83914699162224 0.0111843375899598 0.0711209159566675 GO:0141003 histone H2AX kinase activity 74/3030 354/18639 0.209039548022599 1.28590367511327 0.0119252500768333 0.0754454596697615 GO:0016651 oxidoreductase activity, acting on NAD(P)H 23/3030 88/18639 0.261363636363636 1.60777452745275 0.0120213067478668 0.07566710846373 GO:0071889 14-3-3 protein binding 11/3030 33/18639 0.333333333333333 2.05049504950495 0.0122701900599691 0.0768436145169781 GO:0035173 histone kinase activity 75/3030 360/18639 0.208333333333333 1.28155940594059 0.0123690878528446 0.077073713253906 GO:0048029 monosaccharide binding 20/3030 74/18639 0.27027027027027 1.66256355365266 0.0127036022970147 0.0783012225525762 GO:0051787 misfolded protein binding 7/3030 17/18639 0.411764705882353 2.53296447291788 0.0128091644770315 0.0783012225525762 GO:1901567 fatty acid derivative binding 7/3030 17/18639 0.411764705882353 2.53296447291788 0.0128091644770315 0.0783012225525762 GO:0010484 histone H3 acetyltransferase activity 10/3030 29/18639 0.344827586206897 2.12120177534995 0.0129265688571032 0.0783012225525762 GO:0035198 miRNA binding 13/3030 42/18639 0.30952380952381 1.90403111739745 0.0132054553766471 0.0783012225525762 GO:0019211 phosphatase activator activity 9/3030 25/18639 0.36 2.21453465346535 0.0133596590597908 0.0783012225525762 GO:0019706 protein-cysteine S-palmitoyltransferase activity 9/3030 25/18639 0.36 2.21453465346535 0.0133596590597908 0.0783012225525762 GO:0019707 protein-cysteine S-acyltransferase activity 9/3030 25/18639 0.36 2.21453465346535 0.0133596590597908 0.0783012225525762 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 8/3030 21/18639 0.380952380952381 2.34342291371994 0.0134054557737783 0.0783012225525762 GO:0009931 calcium-dependent protein serine/threonine kinase activity 8/3030 21/18639 0.380952380952381 2.34342291371994 0.0134054557737783 0.0783012225525762 GO:0072542 protein phosphatase activator activity 8/3030 21/18639 0.380952380952381 2.34342291371994 0.0134054557737783 0.0783012225525762 GO:0160215 deacylase activity 18/3030 65/18639 0.276923076923077 1.70348819497334 0.0136125579041583 0.0783012225525762 GO:0019001 guanyl nucleotide binding 82/3030 400/18639 0.205 1.26105445544554 0.0137840417633159 0.0783012225525762 GO:0032561 guanyl ribonucleotide binding 82/3030 400/18639 0.205 1.26105445544554 0.0137840417633159 0.0783012225525762 GO:0019903 protein phosphatase binding 34/3030 144/18639 0.236111111111111 1.45243399339934 0.0138893976211064 0.0783012225525762 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 5/3030 10/18639 0.5 3.07574257425743 0.0138921523883603 0.0783012225525762 GO:0032356 oxidized DNA binding 5/3030 10/18639 0.5 3.07574257425743 0.0138921523883603 0.0783012225525762 GO:0045322 unmethylated CpG binding 5/3030 10/18639 0.5 3.07574257425743 0.0138921523883603 0.0783012225525762 GO:0099122 RNA polymerase II C-terminal domain binding 5/3030 10/18639 0.5 3.07574257425743 0.0138921523883603 0.0783012225525762 GO:0140940 histone H2A methyltransferase activity 5/3030 10/18639 0.5 3.07574257425743 0.0138921523883603 0.0783012225525762 GO:1990259 histone H2AQ104 methyltransferase activity 5/3030 10/18639 0.5 3.07574257425743 0.0138921523883603 0.0783012225525762 GO:0140101 catalytic activity, acting on a tRNA 33/3030 139/18639 0.237410071942446 1.4604245316618 0.0140243467458527 0.0786886423749203 GO:0008017 microtubule binding 59/3030 276/18639 0.213768115942029 1.31499139044339 0.0146991744833891 0.0821034971144259 GO:0000049 tRNA binding 21/3030 80/18639 0.2625 1.61476485148515 0.0151584628436236 0.0842892104309116 GO:0032452 histone demethylase activity 10/3030 30/18639 0.333333333333333 2.05049504950495 0.0166273763759409 0.0916353186940742 GO:0035925 mRNA 3'-UTR AU-rich region binding 10/3030 30/18639 0.333333333333333 2.05049504950495 0.0166273763759409 0.0916353186940742 GO:0015932 nucleobase-containing compound transmembrane transporter activity 16/3030 57/18639 0.280701754385965 1.72673267326733 0.0169957386494574 0.0930433508629037 GO:0051536 iron-sulfur cluster binding 20/3030 76/18639 0.263157894736842 1.61881188118812 0.0170329360047412 0.0930433508629037 GO:0034237 protein kinase A regulatory subunit binding 9/3030 26/18639 0.346153846153846 2.12936024371668 0.0175481235023675 0.0954371629076125 GO:0005154 epidermal growth factor receptor binding 11/3030 35/18639 0.314285714285714 1.93332390381895 0.0194070307593434 0.105086105421772 GO:0051540 metal cluster binding 20/3030 77/18639 0.25974025974026 1.5977883502636 0.0195903278552318 0.105396212308982 GO:0001223 transcription coactivator binding 13/3030 44/18639 0.295454545454545 1.81748424842484 0.0196342943898184 0.105396212308982 GO:0019783 ubiquitin-like protein peptidase activity 30/3030 127/18639 0.236220472440945 1.45310672799563 0.0197761223230214 0.105699964140287 GO:0061980 regulatory RNA binding 16/3030 58/18639 0.275862068965517 1.69696142027996 0.0200243159826591 0.106567175186684 GO:0019888 protein phosphatase regulator activity 26/3030 107/18639 0.242990654205607 1.4947534005737 0.0203589002881337 0.107884770757632 GO:0016411 acylglycerol O-acyltransferase activity 10/3030 31/18639 0.32258064516129 1.98435004790802 0.0210562539859423 0.110634554841392 GO:0016878 acid-thiol ligase activity 10/3030 31/18639 0.32258064516129 1.98435004790802 0.0210562539859423 0.110634554841392 GO:0030331 nuclear estrogen receptor binding 12/3030 40/18639 0.3 1.84544554455446 0.0217205558790736 0.111875572479678 GO:0005536 D-glucose binding 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:0008172 S-methyltransferase activity 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:0034511 U3 snoRNA binding 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:0035252 UDP-xylosyltransferase activity 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:0042285 xylosyltransferase activity 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:0043522 leucine zipper domain binding 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:0048407 platelet-derived growth factor binding 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:1990948 ubiquitin ligase inhibitor activity 5/3030 11/18639 0.454545454545455 2.7961296129613 0.0221044477883235 0.111875572479678 GO:0017069 snRNA binding 15/3030 54/18639 0.277777777777778 1.70874587458746 0.0224389627628599 0.113106966772139 GO:0008320 protein transmembrane transporter activity 9/3030 27/18639 0.333333333333333 2.05049504950495 0.0226161762292699 0.113538698478926 GO:0051213 dioxygenase activity 23/3030 93/18639 0.247311827956989 1.52133503672948 0.0229502681017665 0.114751340508833 GO:0031593 polyubiquitin modification-dependent protein binding 16/3030 59/18639 0.271186440677966 1.66819936230911 0.0234467418341043 0.116762891061403 GO:0051539 4 iron, 4 sulfur cluster binding 13/3030 45/18639 0.288888888888889 1.77709570957096 0.0236145481937244 0.117128159040873 GO:0070577 lysine-acetylated histone binding 8/3030 23/18639 0.347826086956522 2.13964700817908 0.0239218106728997 0.117847197253986 GO:0016409 palmitoyltransferase activity 11/3030 36/18639 0.305555555555556 1.8796204620462 0.0239495917000037 0.117847197253986 GO:0010181 FMN binding 6/3030 15/18639 0.4 2.46059405940594 0.024391247781833 0.11907538287194 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/3030 15/18639 0.4 2.46059405940594 0.024391247781833 0.11907538287194 GO:0120227 acyl-CoA binding 7/3030 19/18639 0.368421052631579 2.26633663366337 0.0246847035816383 0.120035421338163 GO:0016279 protein-lysine N-methyltransferase activity 18/3030 69/18639 0.260869565217391 1.60473525613431 0.0248403125864203 0.120320264090474 GO:0042169 SH2 domain binding 12/3030 41/18639 0.292682926829268 1.8004346776141 0.0262930962533952 0.126861631728444 GO:0016278 lysine N-methyltransferase activity 18/3030 70/18639 0.257142857142857 1.58181046676096 0.0285123988735607 0.136634459253683 GO:0051019 mitogen-activated protein kinase binding 9/3030 28/18639 0.321428571428571 1.9772630834512 0.0286491608112562 0.136634459253683 GO:0141052 histone H3 demethylase activity 9/3030 28/18639 0.321428571428571 1.9772630834512 0.0286491608112562 0.136634459253683 GO:0019213 deacetylase activity 11/3030 37/18639 0.297297297297297 1.82881990901793 0.0292185634315545 0.138816163429607 GO:0004540 RNA nuclease activity 28/3030 121/18639 0.231404958677686 1.42348416659848 0.0305176949543339 0.144434892150283 GO:0019207 kinase regulator activity 59/3030 287/18639 0.205574912891986 1.26459102356229 0.0308323754272651 0.145149826826836 GO:0001091 RNA polymerase II general transcription initiation factor binding 8/3030 24/18639 0.333333333333333 2.05049504950495 0.0309028663566812 0.145149826826836 GO:0051879 Hsp90 protein binding 12/3030 42/18639 0.285714285714286 1.75756718528996 0.0315281526040945 0.147243641076095 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 16/3030 61/18639 0.262295081967213 1.6135043012498 0.0315861359082592 0.147243641076095 GO:0016505 peptidase activator activity involved in apoptotic process 7/3030 20/18639 0.35 2.1530198019802 0.032780317279435 0.148953123339092 GO:0043024 ribosomal small subunit binding 7/3030 20/18639 0.35 2.1530198019802 0.032780317279435 0.148953123339092 GO:0003995 acyl-CoA dehydrogenase activity 5/3030 12/18639 0.416666666666667 2.56311881188119 0.0329138353184768 0.148953123339092 GO:0004300 enoyl-CoA hydratase activity 5/3030 12/18639 0.416666666666667 2.56311881188119 0.0329138353184768 0.148953123339092 GO:0031543 peptidyl-proline dioxygenase activity 5/3030 12/18639 0.416666666666667 2.56311881188119 0.0329138353184768 0.148953123339092 GO:0036009 protein-glutamine N-methyltransferase activity 5/3030 12/18639 0.416666666666667 2.56311881188119 0.0329138353184768 0.148953123339092 GO:0043047 single-stranded telomeric DNA binding 5/3030 12/18639 0.416666666666667 2.56311881188119 0.0329138353184768 0.148953123339092 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 5/3030 12/18639 0.416666666666667 2.56311881188119 0.0329138353184768 0.148953123339092 GO:0061749 forked DNA-dependent helicase activity 13/3030 47/18639 0.276595744680851 1.70147461554666 0.0333150405948968 0.149063388492734 GO:0140938 histone H3 methyltransferase activity 13/3030 47/18639 0.276595744680851 1.70147461554666 0.0333150405948968 0.149063388492734 GO:1990518 single-stranded 3'-5' DNA helicase activity 13/3030 47/18639 0.276595744680851 1.70147461554666 0.0333150405948968 0.149063388492734 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 6/3030 16/18639 0.375 2.30680693069307 0.0337796872310147 0.149063388492734 GO:0005159 insulin-like growth factor receptor binding 6/3030 16/18639 0.375 2.30680693069307 0.0337796872310147 0.149063388492734 GO:0008142 oxysterol binding 6/3030 16/18639 0.375 2.30680693069307 0.0337796872310147 0.149063388492734 GO:0030275 LRR domain binding 6/3030 16/18639 0.375 2.30680693069307 0.0337796872310147 0.149063388492734 GO:0019208 phosphatase regulator activity 27/3030 117/18639 0.230769230769231 1.41957349581112 0.0342474112798567 0.150591453854689 GO:0030159 signaling receptor complex adaptor activity 14/3030 52/18639 0.269230769230769 1.65616907844631 0.0346679406688185 0.151901930845707 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 9/3030 29/18639 0.310344827586207 1.90908159781495 0.0357243271906251 0.155432160408334 GO:0097472 cyclin-dependent protein kinase activity 9/3030 29/18639 0.310344827586207 1.90908159781495 0.0357243271906251 0.155432160408334 GO:0016758 hexosyltransferase activity 42/3030 197/18639 0.213197969543147 1.31148414333819 0.0362872847253233 0.157329486221681 GO:0008173 RNA methyltransferase activity 17/3030 67/18639 0.253731343283582 1.56082458992168 0.0368066108260153 0.159025078133306 GO:0009378 four-way junction helicase activity 13/3030 48/18639 0.270833333333333 1.66602722772277 0.0391124967829225 0.167239641416634 GO:0036121 double-stranded DNA helicase activity 13/3030 48/18639 0.270833333333333 1.66602722772277 0.0391124967829225 0.167239641416634 GO:0043138 3'-5' DNA helicase activity 13/3030 48/18639 0.270833333333333 1.66602722772277 0.0391124967829225 0.167239641416634 GO:0015035 protein-disulfide reductase activity 10/3030 34/18639 0.294117647058824 1.80926033779849 0.0393951584178213 0.167294508349652 GO:0016831 carboxy-lyase activity 10/3030 34/18639 0.294117647058824 1.80926033779849 0.0393951584178213 0.167294508349652 GO:0004518 nuclease activity 44/3030 209/18639 0.210526315789474 1.2950495049505 0.0395683908151861 0.167456671026726 GO:0051018 protein kinase A binding 14/3030 53/18639 0.264150943396226 1.62492060526807 0.0402997905377437 0.169444568547428 GO:0008170 N-methyltransferase activity 23/3030 98/18639 0.23469387755102 1.44371590220247 0.0403114094528156 0.169444568547428 GO:0008194 UDP-glycosyltransferase activity 32/3030 145/18639 0.220689655172414 1.35756913622397 0.0405062494162821 0.16968834214929 GO:0008408 3'-5' exonuclease activity 15/3030 58/18639 0.258620689655172 1.59090133151246 0.041116221370952 0.171663685185119 GO:1904047 S-adenosyl-L-methionine binding 7/3030 21/18639 0.333333333333333 2.05049504950495 0.0424677480322635 0.176711434765123 GO:0015215 nucleotide transmembrane transporter activity 9/3030 30/18639 0.3 1.84544554455446 0.0439087346826326 0.182096424770784 GO:0004550 nucleoside diphosphate kinase activity 6/3030 17/18639 0.352941176470588 2.17111240535818 0.0452181541877329 0.185663944346983 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 6/3030 17/18639 0.352941176470588 2.17111240535818 0.0452181541877329 0.185663944346983 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 6/3030 17/18639 0.352941176470588 2.17111240535818 0.0452181541877329 0.185663944346983 GO:0060590 ATPase regulator activity 13/3030 49/18639 0.26530612244898 1.63202667205496 0.045588001609438 0.18567026145053 GO:0002020 protease binding 30/3030 136/18639 0.220588235294118 1.35694525334886 0.0463609011682231 0.18567026145053 GO:0016779 nucleotidyltransferase activity 30/3030 136/18639 0.220588235294118 1.35694525334886 0.0463609011682231 0.18567026145053 GO:0140789 histone phosphatase activity 30/3030 136/18639 0.220588235294118 1.35694525334886 0.0463609011682231 0.18567026145053 GO:0005338 nucleotide-sugar transmembrane transporter activity 5/3030 13/18639 0.384615384615385 2.36595582635187 0.0464947713987999 0.18567026145053 GO:0019104 DNA N-glycosylase activity 5/3030 13/18639 0.384615384615385 2.36595582635187 0.0464947713987999 0.18567026145053 GO:0051011 microtubule minus-end binding 5/3030 13/18639 0.384615384615385 2.36595582635187 0.0464947713987999 0.18567026145053 GO:0051287 NAD binding 14/3030 54/18639 0.259259259259259 1.59482948294829 0.0465510802589531 0.18567026145053 GO:0101005 deubiquitinase activity 26/3030 115/18639 0.226086956521739 1.3907705553164 0.0465672994444474 0.18567026145053 GO:0019902 phosphatase binding 40/3030 190/18639 0.210526315789474 1.2950495049505 0.0477995859128855 0.189972713243519 GO:0052742 phosphatidylinositol kinase activity 8/3030 26/18639 0.307692307692308 1.89276466108149 0.0487631021277266 0.19196237517022 GO:0070006 metalloaminopeptidase activity 8/3030 26/18639 0.307692307692308 1.89276466108149 0.0487631021277266 0.19196237517022 GO:0016757 glycosyltransferase activity 54/3030 267/18639 0.202247191011236 1.24412059183446 0.0487646356279188 0.19196237517022 GO:0004177 aminopeptidase activity 11/3030 40/18639 0.275 1.69165841584158 0.0498903731768567 0.195154772048272 GO:0004532 RNA exonuclease activity 11/3030 40/18639 0.275 1.69165841584158 0.0498903731768567 0.195154772048272 GO:0019210 kinase inhibitor activity 21/3030 90/18639 0.233333333333333 1.43534653465347 0.0511737168682951 0.199545311058761 GO:0008327 methyl-CpG binding 9/3030 31/18639 0.290322580645161 1.78591504311722 0.0532574767858242 0.206646295975942 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 15/3030 60/18639 0.25 1.53787128712871 0.0537560562093368 0.206646295975942 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 7/3030 22/18639 0.318181818181818 1.95729072907291 0.0538280270969591 0.206646295975942 GO:0050321 tau-protein kinase activity 7/3030 22/18639 0.318181818181818 1.95729072907291 0.0538280270969591 0.206646295975942 GO:0070034 telomerase RNA binding 7/3030 22/18639 0.318181818181818 1.95729072907291 0.0538280270969591 0.206646295975942 GO:0055106 ubiquitin-protein transferase regulator activity 10/3030 36/18639 0.277777777777778 1.70874587458746 0.0564061086278313 0.215875230550959 GO:0008234 cysteine-type peptidase activity 39/3030 187/18639 0.20855614973262 1.28293005771165 0.0566836973115415 0.216270106665574 GO:0031490 chromatin DNA binding 28/3030 128/18639 0.21875 1.34563737623762 0.0578465713462421 0.220029903280185 GO:0016830 carbon-carbon lyase activity 13/3030 51/18639 0.254901960784314 1.56802562609202 0.0606902791293046 0.230140508013265 GO:0016836 hydro-lyase activity 15/3030 61/18639 0.245901639344262 1.51266028242168 0.0609853780466449 0.230481594515534 GO:0061659 ubiquitin-like protein ligase activity 72/3030 372/18639 0.193548387096774 1.19061002874481 0.0611519714480732 0.230481594515534 GO:0032454 histone H3K9 demethylase activity 5/3030 14/18639 0.357142857142857 2.19695898161245 0.0629257483441605 0.232318342893598 GO:0098847 sequence-specific single stranded DNA binding 5/3030 14/18639 0.357142857142857 2.19695898161245 0.0629257483441605 0.232318342893598 GO:0031369 translation initiation factor binding 9/3030 32/18639 0.28125 1.7301051980198 0.0638122735493383 0.232318342893598 GO:0001094 TFIID-class transcription factor complex binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0008140 cAMP response element binding protein binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0042975 peroxisome proliferator activated receptor binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0043295 glutathione binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0043422 protein kinase B binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0047429 nucleoside triphosphate diphosphatase activity 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0051864 histone H3K36 demethylase activity 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0051880 G-quadruplex DNA binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0070513 death domain binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0098505 G-rich strand telomeric DNA binding 4/3030 10/18639 0.4 2.46059405940594 0.0644496048027401 0.232318342893598 GO:0016829 lyase activity 41/3030 200/18639 0.205 1.26105445544554 0.0650326029254207 0.233740369934845 GO:0003887 DNA-directed DNA polymerase activity 7/3030 23/18639 0.304347826086957 1.87219113215669 0.066911996782485 0.239109152767381 GO:0044013 histone H2B acetyltransferase activity 7/3030 23/18639 0.304347826086957 1.87219113215669 0.066911996782485 0.239109152767381 GO:0031492 nucleosomal DNA binding 11/3030 42/18639 0.261904761904762 1.61110325318246 0.0681285180452983 0.24275678843727 GO:0051219 phosphoprotein binding 21/3030 93/18639 0.225806451612903 1.38904503353561 0.0690343078968137 0.245279489375499 GO:0051537 2 iron, 2 sulfur cluster binding 8/3030 28/18639 0.285714285714286 1.75756718528996 0.0722216033944574 0.255870823454649 GO:0061630 ubiquitin protein ligase activity 68/3030 353/18639 0.192634560906516 1.18498864050711 0.0726081581797673 0.256507453398608 GO:0017124 SH3 domain binding 25/3030 115/18639 0.217391304347826 1.33727938011192 0.0743047594220365 0.260339555525723 GO:0005346 purine ribonucleotide transmembrane transporter activity 6/3030 19/18639 0.315789473684211 1.94257425742574 0.074532695331961 0.260339555525723 GO:0046527 glucosyltransferase activity 6/3030 19/18639 0.315789473684211 1.94257425742574 0.074532695331961 0.260339555525723 GO:1990380 K48-linked deubiquitinase activity 6/3030 19/18639 0.315789473684211 1.94257425742574 0.074532695331961 0.260339555525723 GO:0004521 RNA endonuclease activity 17/3030 73/18639 0.232876712328767 1.43253763732538 0.0749929650932453 0.261211451448383 GO:0140416 transcription regulator inhibitor activity 9/3030 33/18639 0.272727272727273 1.67767776777678 0.0756004580932289 0.262589826430263 GO:0032934 sterol binding 16/3030 68/18639 0.235294117647059 1.44740827023879 0.0762536001985472 0.263382908763784 GO:1990841 promoter-specific chromatin binding 16/3030 68/18639 0.235294117647059 1.44740827023879 0.0762536001985472 0.263382908763784 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 10/3030 38/18639 0.263157894736842 1.61881188118812 0.0776214272734782 0.26736269394198 GO:1901505 carbohydrate derivative transmembrane transporter activity 13/3030 53/18639 0.245283018867925 1.50885484774893 0.0788103874082765 0.270473221292655 GO:0140693 molecular condensate scaffold activity 12/3030 48/18639 0.25 1.53787128712871 0.0790018639895989 0.270473221292655 GO:0004527 exonuclease activity 19/3030 84/18639 0.226190476190476 1.39140735502122 0.0796151014288864 0.270473221292655 GO:0004860 protein kinase inhibitor activity 19/3030 84/18639 0.226190476190476 1.39140735502122 0.0796151014288864 0.270473221292655 GO:0051117 ATPase binding 19/3030 84/18639 0.226190476190476 1.39140735502122 0.0796151014288864 0.270473221292655 GO:0016835 carbon-oxygen lyase activity 18/3030 79/18639 0.227848101265823 1.40160421105402 0.0814604023626286 0.27324214020215 GO:0046332 SMAD binding 18/3030 79/18639 0.227848101265823 1.40160421105402 0.0814604023626286 0.27324214020215 GO:0140612 DNA damage sensor activity 7/3030 24/18639 0.291666666666667 1.79418316831683 0.0817392857813453 0.27324214020215 GO:0000774 adenyl-nucleotide exchange factor activity 5/3030 15/18639 0.333333333333333 2.05049504950495 0.0821929986253242 0.27324214020215 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 5/3030 15/18639 0.333333333333333 2.05049504950495 0.0821929986253242 0.27324214020215 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 5/3030 15/18639 0.333333333333333 2.05049504950495 0.0821929986253242 0.27324214020215 GO:0015556 C4-dicarboxylate transmembrane transporter activity 5/3030 15/18639 0.333333333333333 2.05049504950495 0.0821929986253242 0.27324214020215 GO:0140776 protein-containing complex destabilizing activity 5/3030 15/18639 0.333333333333333 2.05049504950495 0.0821929986253242 0.27324214020215 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 26/3030 122/18639 0.213114754098361 1.31097224476546 0.0847687530493757 0.281051480698465 GO:0003785 actin monomer binding 8/3030 29/18639 0.275862068965517 1.69696142027996 0.0861253276625841 0.284030335908522 GO:0051861 glycolipid binding 8/3030 29/18639 0.275862068965517 1.69696142027996 0.0861253276625841 0.284030335908522 GO:1990782 protein tyrosine kinase binding 25/3030 117/18639 0.213675213675214 1.31441990352881 0.0874323339549577 0.284772223715504 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 9/3030 34/18639 0.264705882352941 1.62833430401864 0.0886343659763757 0.284772223715504 GO:0030332 cyclin binding 9/3030 34/18639 0.264705882352941 1.62833430401864 0.0886343659763757 0.284772223715504 GO:0000099 sulfur amino acid transmembrane transporter activity 4/3030 11/18639 0.363636363636364 2.23690369036904 0.088646837382407 0.284772223715504 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 4/3030 11/18639 0.363636363636364 2.23690369036904 0.088646837382407 0.284772223715504 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4/3030 11/18639 0.363636363636364 2.23690369036904 0.088646837382407 0.284772223715504 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 4/3030 11/18639 0.363636363636364 2.23690369036904 0.088646837382407 0.284772223715504 GO:0032794 GTPase activating protein binding 4/3030 11/18639 0.363636363636364 2.23690369036904 0.088646837382407 0.284772223715504 GO:0047676 arachidonate-CoA ligase activity 4/3030 11/18639 0.363636363636364 2.23690369036904 0.088646837382407 0.284772223715504 GO:1900750 oligopeptide binding 4/3030 11/18639 0.363636363636364 2.23690369036904 0.088646837382407 0.284772223715504 GO:0140767 enzyme-substrate adaptor activity 29/3030 139/18639 0.20863309352518 1.28340337630885 0.0894885574777935 0.285962966002387 GO:0016776 phosphotransferase activity, phosphate group as acceptor 10/3030 39/18639 0.256410256410256 1.57730388423458 0.0898551354988272 0.285962966002387 GO:0016790 thiolester hydrolase activity 11/3030 44/18639 0.25 1.53787128712871 0.0901705804088172 0.285962966002387 GO:0019205 nucleobase-containing compound kinase activity 11/3030 44/18639 0.25 1.53787128712871 0.0901705804088172 0.285962966002387 GO:0043014 alpha-tubulin binding 11/3030 44/18639 0.25 1.53787128712871 0.0901705804088172 0.285962966002387 GO:0016791 phosphatase activity 53/3030 273/18639 0.194139194139194 1.19424436949189 0.0918966659738919 0.290693535223536 GO:0140664 ATP-dependent DNA damage sensor activity 6/3030 20/18639 0.3 1.84544554455446 0.0924265716401863 0.291625824004659 GO:0050660 flavin adenine dinucleotide binding 19/3030 86/18639 0.22093023255814 1.35904904443933 0.0960530598435309 0.302298970065935 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 14/3030 60/18639 0.233333333333333 1.43534653465347 0.0982897334027533 0.302350350087379 GO:0017056 structural constituent of nuclear pore 7/3030 25/18639 0.28 1.72241584158416 0.0982984828496761 0.302350350087379 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 7/3030 25/18639 0.28 1.72241584158416 0.0982984828496761 0.302350350087379 GO:0033192 calmodulin-dependent protein phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:0140791 histone H2AXS140 phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:1990439 MAP kinase serine/threonine phosphatase activity 18/3030 81/18639 0.222222222222222 1.36699669966997 0.0987515256333777 0.302350350087379 GO:0008374 O-acyltransferase activity 13/3030 55/18639 0.236363636363636 1.45398739873987 0.100055083430539 0.305586954319872 GO:0070566 adenylyltransferase activity 8/3030 30/18639 0.266666666666667 1.64039603960396 0.10147681601893 0.309167694996249 GO:0000175 3'-5'-RNA exonuclease activity 9/3030 35/18639 0.257142857142857 1.58181046676096 0.102911120147778 0.312004374042164 GO:0034061 DNA polymerase activity 9/3030 35/18639 0.257142857142857 1.58181046676096 0.102911120147778 0.312004374042164 GO:0034450 ubiquitin-ubiquitin ligase activity 5/3030 16/18639 0.3125 1.92233910891089 0.104199049259101 0.314371827448383 GO:0070411 I-SMAD binding 5/3030 16/18639 0.3125 1.92233910891089 0.104199049259101 0.314371827448383 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 18/3030 82/18639 0.219512195121951 1.35032600821058 0.108200814987329 0.324628893546961 GO:0033549 MAP kinase phosphatase activity 18/3030 82/18639 0.219512195121951 1.35032600821058 0.108200814987329 0.324628893546961 GO:0004721 phosphoprotein phosphatase activity 35/3030 175/18639 0.2 1.23029702970297 0.108384162845518 0.324628893546961 GO:0005123 death receptor binding 6/3030 21/18639 0.285714285714286 1.75756718528996 0.112410101083356 0.335068570536925 GO:0140312 cargo adaptor activity 6/3030 21/18639 0.285714285714286 1.75756718528996 0.112410101083356 0.335068570536925 GO:0005095 GTPase inhibitor activity 4/3030 12/18639 0.333333333333333 2.05049504950495 0.116513338414372 0.340046979641472 GO:0016273 arginine N-methyltransferase activity 4/3030 12/18639 0.333333333333333 2.05049504950495 0.116513338414372 0.340046979641472 GO:0016274 protein-arginine N-methyltransferase activity 4/3030 12/18639 0.333333333333333 2.05049504950495 0.116513338414372 0.340046979641472 GO:0035251 UDP-glucosyltransferase activity 4/3030 12/18639 0.333333333333333 2.05049504950495 0.116513338414372 0.340046979641472 GO:0097371 MDM2/MDM4 family protein binding 4/3030 12/18639 0.333333333333333 2.05049504950495 0.116513338414372 0.340046979641472 GO:1990817 poly(A) RNA polymerase activity 4/3030 12/18639 0.333333333333333 2.05049504950495 0.116513338414372 0.340046979641472 GO:0008143 poly(A) binding 7/3030 26/18639 0.269230769230769 1.65616907844631 0.116548359957763 0.340046979641472 GO:0015216 purine nucleotide transmembrane transporter activity 7/3030 26/18639 0.269230769230769 1.65616907844631 0.116548359957763 0.340046979641472 GO:0070412 R-SMAD binding 7/3030 26/18639 0.269230769230769 1.65616907844631 0.116548359957763 0.340046979641472 GO:0001727 lipid kinase activity 10/3030 41/18639 0.24390243902439 1.50036223134509 0.117574792259062 0.342236484509946 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 18/3030 83/18639 0.216867469879518 1.33405702015985 0.118186608983033 0.343211698217708 GO:0004519 endonuclease activity 26/3030 127/18639 0.204724409448819 1.25935916426288 0.122274272165338 0.354252564217334 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 25/3030 122/18639 0.204918032786885 1.2605502353514 0.126654544658447 0.365401106487016 GO:0017018 myosin phosphatase activity 18/3030 84/18639 0.214285714285714 1.31817538896747 0.128706111043255 0.365401106487016 GO:0004549 tRNA-specific ribonuclease activity 5/3030 17/18639 0.294117647058824 1.80926033779849 0.128774422205505 0.365401106487016 GO:0004659 prenyltransferase activity 5/3030 17/18639 0.294117647058824 1.80926033779849 0.128774422205505 0.365401106487016 GO:0008484 sulfuric ester hydrolase activity 5/3030 17/18639 0.294117647058824 1.80926033779849 0.128774422205505 0.365401106487016 GO:0016805 dipeptidase activity 5/3030 17/18639 0.294117647058824 1.80926033779849 0.128774422205505 0.365401106487016 GO:0032183 SUMO binding 5/3030 17/18639 0.294117647058824 1.80926033779849 0.128774422205505 0.365401106487016 GO:0032977 membrane insertase activity 5/3030 17/18639 0.294117647058824 1.80926033779849 0.128774422205505 0.365401106487016 GO:0070402 NADPH binding 5/3030 17/18639 0.294117647058824 1.80926033779849 0.128774422205505 0.365401106487016 GO:0032931 histone H3K56 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0043992 histone H3K9 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0043993 histone H3K18 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0043994 histone H3K23 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0043999 histone H2AK5 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0044012 histone H2AK9 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0044014 histone H2BK5 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0044015 histone H2BK12 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0044016 histone H3K4 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0044017 histone H3K27 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0044018 histone H3K36 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0046972 histone H4K16 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0061133 endopeptidase activator activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0140517 protein-RNA adaptor activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0140908 histone H3K122 acetyltransferase activity 6/3030 22/18639 0.272727272727273 1.67767776777678 0.134378378828254 0.368648649882821 GO:0070717 poly-purine tract binding 8/3030 32/18639 0.25 1.53787128712871 0.136394255616901 0.371781893574543 GO:0001671 ATPase activator activity 7/3030 27/18639 0.259259259259259 1.59482948294829 0.136419969013239 0.371781893574543 GO:0005385 zinc ion transmembrane transporter activity 7/3030 27/18639 0.259259259259259 1.59482948294829 0.136419969013239 0.371781893574543 GO:0003678 DNA helicase activity 16/3030 74/18639 0.216216216216216 1.33005084292213 0.137578859475141 0.373876999969877 GO:0017116 single-stranded DNA helicase activity 13/3030 58/18639 0.224137931034483 1.37878115397747 0.137791765311479 0.373876999969877 GO:0015078 proton transmembrane transporter activity 36/3030 185/18639 0.194594594594595 1.19704575862992 0.139251049206926 0.377011574272027 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 11/3030 48/18639 0.229166666666667 1.40971534653465 0.145735661525161 0.393708540939433 GO:0004712 protein serine/threonine/tyrosine kinase activity 10/3030 43/18639 0.232558139534884 1.43057794151508 0.149499266522195 0.40299802279896 GO:0019887 protein kinase regulator activity 48/3030 255/18639 0.188235294117647 1.15792661619103 0.150873124967161 0.405819251538569 GO:0004843 cysteine-type deubiquitinase activity 22/3030 108/18639 0.203703703703704 1.2530803080308 0.151274364105116 0.406017773788622 GO:0043531 ADP binding 9/3030 38/18639 0.236842105263158 1.45693069306931 0.152947215654715 0.40962105272537 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 5/3030 18/18639 0.277777777777778 1.70874587458746 0.155691036802656 0.411635150608302 GO:0017128 phospholipid scramblase activity 5/3030 18/18639 0.277777777777778 1.70874587458746 0.155691036802656 0.411635150608302 GO:0035615 clathrin adaptor activity 5/3030 18/18639 0.277777777777778 1.70874587458746 0.155691036802656 0.411635150608302 GO:0070064 proline-rich region binding 5/3030 18/18639 0.277777777777778 1.70874587458746 0.155691036802656 0.411635150608302 GO:0070628 proteasome binding 5/3030 18/18639 0.277777777777778 1.70874587458746 0.155691036802656 0.411635150608302 GO:1990381 ubiquitin-specific protease binding 5/3030 18/18639 0.277777777777778 1.70874587458746 0.155691036802656 0.411635150608302 GO:0015485 cholesterol binding 12/3030 54/18639 0.222222222222222 1.36699669966997 0.156876878311699 0.412959270355433 GO:0030971 receptor tyrosine kinase binding 17/3030 81/18639 0.209876543209877 1.29105243857719 0.156952624813805 0.412959270355433 GO:0000295 adenine nucleotide transmembrane transporter activity 6/3030 23/18639 0.260869565217391 1.60473525613431 0.158190043079702 0.412959270355433 GO:0005158 insulin receptor binding 6/3030 23/18639 0.260869565217391 1.60473525613431 0.158190043079702 0.412959270355433 GO:0140102 catalytic activity, acting on a rRNA 6/3030 23/18639 0.260869565217391 1.60473525613431 0.158190043079702 0.412959270355433 GO:0140103 catalytic activity, acting on a glycoprotein 6/3030 23/18639 0.260869565217391 1.60473525613431 0.158190043079702 0.412959270355433 GO:0016763 pentosyltransferase activity 11/3030 49/18639 0.224489795918367 1.38094564558497 0.161916334187176 0.421798853764911 GO:0001046 core promoter sequence-specific DNA binding 10/3030 44/18639 0.227272727272727 1.39806480648065 0.166948880084953 0.433997088690444 GO:0000217 DNA secondary structure binding 9/3030 39/18639 0.230769230769231 1.41957349581112 0.171874839701481 0.445867784999658 GO:0008175 tRNA methyltransferase activity 8/3030 34/18639 0.235294117647059 1.44740827023879 0.176529472316199 0.456034470150182 GO:0052866 phosphatidylinositol phosphate phosphatase activity 8/3030 34/18639 0.235294117647059 1.44740827023879 0.176529472316199 0.456034470150182 GO:0005085 guanyl-nucleotide exchange factor activity 43/3030 230/18639 0.18695652173913 1.15006026689625 0.178147210246533 0.459256841383995 GO:0106222 lncRNA binding 7/3030 29/18639 0.241379310344828 1.48484124274496 0.180631182214882 0.461227866150716 GO:0004065 arylsulfatase activity 4/3030 14/18639 0.285714285714286 1.75756718528996 0.181515482807701 0.461227866150716 GO:0005347 ATP transmembrane transporter activity 4/3030 14/18639 0.285714285714286 1.75756718528996 0.181515482807701 0.461227866150716 GO:0008474 palmitoyl-(protein) hydrolase activity 4/3030 14/18639 0.285714285714286 1.75756718528996 0.181515482807701 0.461227866150716 GO:0008494 translation activator activity 4/3030 14/18639 0.285714285714286 1.75756718528996 0.181515482807701 0.461227866150716 GO:0098599 palmitoyl hydrolase activity 4/3030 14/18639 0.285714285714286 1.75756718528996 0.181515482807701 0.461227866150716 GO:1990825 sequence-specific mRNA binding 4/3030 14/18639 0.285714285714286 1.75756718528996 0.181515482807701 0.461227866150716 GO:0043998 histone H2A acetyltransferase activity 6/3030 24/18639 0.25 1.53787128712871 0.183673628845821 0.463559588781436 GO:0003756 protein disulfide isomerase activity 5/3030 19/18639 0.263157894736842 1.61881188118812 0.184676158756475 0.463559588781436 GO:0005520 insulin-like growth factor binding 5/3030 19/18639 0.263157894736842 1.61881188118812 0.184676158756475 0.463559588781436 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/3030 19/18639 0.263157894736842 1.61881188118812 0.184676158756475 0.463559588781436 GO:0042800 histone H3K4 methyltransferase activity 5/3030 19/18639 0.263157894736842 1.61881188118812 0.184676158756475 0.463559588781436 GO:0140036 ubiquitin-modified protein reader activity 5/3030 19/18639 0.263157894736842 1.61881188118812 0.184676158756475 0.463559588781436 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 9/3030 40/18639 0.225 1.38408415841584 0.191819454245287 0.478583749022446 GO:0061791 GTPase motor activity 9/3030 40/18639 0.225 1.38408415841584 0.191819454245287 0.478583749022446 GO:1990606 membrane scission GTPase motor activity 9/3030 40/18639 0.225 1.38408415841584 0.191819454245287 0.478583749022446 GO:0035091 phosphatidylinositol binding 52/3030 284/18639 0.183098591549296 1.12632826662948 0.192465685856561 0.479231828237219 GO:0043015 gamma-tubulin binding 8/3030 35/18639 0.228571428571429 1.40605374823197 0.198342317403139 0.492874696552891 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 34/3030 181/18639 0.187845303867403 1.15552759695859 0.202554251428421 0.502334543542484 GO:0030291 protein serine/threonine kinase inhibitor activity 10/3030 46/18639 0.217391304347826 1.33727938011192 0.204559924332034 0.506015751433826 GO:0005548 phospholipid transporter activity 14/3030 68/18639 0.205882352941176 1.26648223645894 0.206448487357236 0.506015751433826 GO:0003707 nuclear steroid receptor activity 6/3030 25/18639 0.24 1.47635643564356 0.210634201265656 0.506015751433826 GO:0017025 TBP-class protein binding 6/3030 25/18639 0.24 1.47635643564356 0.210634201265656 0.506015751433826 GO:0047617 fatty acyl-CoA hydrolase activity 6/3030 25/18639 0.24 1.47635643564356 0.210634201265656 0.506015751433826 GO:0019838 growth factor binding 26/3030 136/18639 0.191176470588235 1.17601921956902 0.211570576778433 0.506015751433826 GO:0000182 rDNA binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0005031 tumor necrosis factor receptor activity 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0005131 growth hormone receptor binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0005522 profilin binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0005528 FK506 binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0008190 eukaryotic initiation factor 4E binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0016427 tRNA (cytidine) methyltransferase activity 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0016783 sulfurtransferase activity 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0016868 intramolecular phosphotransferase activity 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0030957 Tat protein binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0031419 cobalamin binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0050815 phosphoserine residue binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0070097 delta-catenin binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0097177 mitochondrial ribosome binding 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0140999 histone H3K4 trimethyltransferase activity 3/3030 10/18639 0.3 1.84544554455446 0.213366104877603 0.506015751433826 GO:0042578 phosphoric ester hydrolase activity 65/3030 363/18639 0.179063360881543 1.10150560510597 0.213424385483783 0.506015751433826 GO:0005080 protein kinase C binding 11/3030 52/18639 0.211538461538462 1.30127570449353 0.215347318298973 0.507848414827812 GO:0016004 phospholipase activator activity 5/3030 20/18639 0.25 1.53787128712871 0.215426021128572 0.507848414827812 GO:0016408 C-acyltransferase activity 5/3030 20/18639 0.25 1.53787128712871 0.215426021128572 0.507848414827812 GO:0004467 long-chain fatty acid-CoA ligase activity 4/3030 15/18639 0.266666666666667 1.64039603960396 0.217632749783111 0.509178508926525 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/3030 15/18639 0.266666666666667 1.64039603960396 0.217632749783111 0.509178508926525 GO:0047372 monoacylglycerol lipase activity 4/3030 15/18639 0.266666666666667 1.64039603960396 0.217632749783111 0.509178508926525 GO:0050700 CARD domain binding 4/3030 15/18639 0.266666666666667 1.64039603960396 0.217632749783111 0.509178508926525 GO:0005484 SNAP receptor activity 8/3030 36/18639 0.222222222222222 1.36699669966997 0.221179325045628 0.515530757625148 GO:0044390 ubiquitin-like protein conjugating enzyme binding 8/3030 36/18639 0.222222222222222 1.36699669966997 0.221179325045628 0.515530757625148 GO:0043495 protein-membrane adaptor activity 10/3030 47/18639 0.212765957446809 1.30882662734359 0.224591660748819 0.522502175100442 GO:0004722 protein serine/threonine phosphatase activity 20/3030 103/18639 0.194174757281553 1.19446313563395 0.22610063244471 0.525027685826667 GO:0019003 GDP binding 15/3030 75/18639 0.2 1.23029702970297 0.229490603173505 0.531903454084386 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 25/3030 132/18639 0.189393939393939 1.16505400540054 0.231841883344886 0.536350625648618 GO:0016860 intramolecular oxidoreductase activity 11/3030 53/18639 0.207547169811321 1.27672333271063 0.234609244280295 0.541742016587647 GO:0016289 acyl-CoA hydrolase activity 6/3030 26/18639 0.230769230769231 1.41957349581112 0.238859953658025 0.548493226918427 GO:0097602 cullin family protein binding 6/3030 26/18639 0.230769230769231 1.41957349581112 0.238859953658025 0.548493226918427 GO:0120014 phospholipid transfer activity 6/3030 26/18639 0.230769230769231 1.41957349581112 0.238859953658025 0.548493226918427 GO:0016879 ligase activity, forming carbon-nitrogen bonds 10/3030 48/18639 0.208333333333333 1.28155940594059 0.245343239491887 0.562339402901923 GO:0019200 carbohydrate kinase activity 5/3030 21/18639 0.238095238095238 1.46463932107496 0.247618496142702 0.566507260547879 GO:0004707 MAP kinase activity 4/3030 16/18639 0.25 1.53787128712871 0.255443983291115 0.576015052559812 GO:0008296 3'-5'-DNA exonuclease activity 4/3030 16/18639 0.25 1.53787128712871 0.255443983291115 0.576015052559812 GO:0043023 ribosomal large subunit binding 4/3030 16/18639 0.25 1.53787128712871 0.255443983291115 0.576015052559812 GO:0097027 ubiquitin-protein transferase activator activity 4/3030 16/18639 0.25 1.53787128712871 0.255443983291115 0.576015052559812 GO:0008378 galactosyltransferase activity 7/3030 32/18639 0.21875 1.34563737623762 0.256136518589891 0.576015052559812 GO:0008375 acetylglucosaminyltransferase activity 9/3030 43/18639 0.209302325581395 1.28752014736357 0.256911717304403 0.576015052559812 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 9/3030 43/18639 0.209302325581395 1.28752014736357 0.256911717304403 0.576015052559812 GO:0004713 protein tyrosine kinase activity 26/3030 140/18639 0.185714285714286 1.14241867043847 0.259288489580473 0.576015052559812 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0002162 dystroglycan binding 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0008526 phosphatidylinositol transfer activity 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0015217 ADP transmembrane transporter activity 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0034056 estrogen response element binding 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0034713 type I transforming growth factor beta receptor binding 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0048185 activin binding 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0070990 snRNP binding 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0140031 phosphorylation-dependent protein binding 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0140537 transcription regulator activator activity 3/3030 11/18639 0.272727272727273 1.67767776777678 0.260135830188302 0.576015052559812 GO:0098531 ligand-modulated transcription factor activity 12/3030 60/18639 0.2 1.23029702970297 0.262280145949471 0.579727951831272 GO:0004364 glutathione transferase activity 6/3030 27/18639 0.222222222222222 1.36699669966997 0.268128520699392 0.590549494968465 GO:0016405 CoA-ligase activity 6/3030 27/18639 0.222222222222222 1.36699669966997 0.268128520699392 0.590549494968465 GO:0008235 metalloexopeptidase activity 13/3030 66/18639 0.196969696969697 1.21165616561656 0.268984427369762 0.591384202018626 GO:0005518 collagen binding 14/3030 72/18639 0.194444444444444 1.19612211221122 0.274815519301686 0.603134945016089 GO:0008649 rRNA methyltransferase activity 5/3030 22/18639 0.227272727272727 1.39806480648065 0.280924412999893 0.612207859613123 GO:0016881 acid-amino acid ligase activity 5/3030 22/18639 0.227272727272727 1.39806480648065 0.280924412999893 0.612207859613123 GO:0031683 G-protein beta/gamma-subunit complex binding 5/3030 22/18639 0.227272727272727 1.39806480648065 0.280924412999893 0.612207859613123 GO:0140035 ubiquitin-like protein reader activity 5/3030 22/18639 0.227272727272727 1.39806480648065 0.280924412999893 0.612207859613123 GO:0019905 syntaxin binding 12/3030 61/18639 0.19672131147541 1.21012822593735 0.28188146809289 0.613215825324883 GO:0019239 deaminase activity 7/3030 33/18639 0.212121212121212 1.30486048604861 0.28313720068058 0.613793931545313 GO:0140311 protein sequestering activity 7/3030 33/18639 0.212121212121212 1.30486048604861 0.28313720068058 0.613793931545313 GO:0032813 tumor necrosis factor receptor superfamily binding 10/3030 50/18639 0.2 1.23029702970297 0.28868234365897 0.624722698319586 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/3030 17/18639 0.235294117647059 1.44740827023879 0.294419232855918 0.632720708390534 GO:0008429 phosphatidylethanolamine binding 4/3030 17/18639 0.235294117647059 1.44740827023879 0.294419232855918 0.632720708390534 GO:0048038 quinone binding 4/3030 17/18639 0.235294117647059 1.44740827023879 0.294419232855918 0.632720708390534 GO:1990226 histone methyltransferase binding 4/3030 17/18639 0.235294117647059 1.44740827023879 0.294419232855918 0.632720708390534 GO:0019789 SUMO transferase activity 6/3030 28/18639 0.214285714285714 1.31817538896747 0.298212819739362 0.635494829783781 GO:0046625 sphingolipid binding 6/3030 28/18639 0.214285714285714 1.31817538896747 0.298212819739362 0.635494829783781 GO:0046915 transition metal ion transmembrane transporter activity 9/3030 45/18639 0.2 1.23029702970297 0.30372556759945 0.635494829783781 GO:0140303 intramembrane lipid transporter activity 9/3030 45/18639 0.2 1.23029702970297 0.30372556759945 0.635494829783781 GO:0004526 ribonuclease P activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0005025 transforming growth factor beta receptor activity, type I 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0005026 transforming growth factor beta receptor activity, type II 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0005078 MAP-kinase scaffold activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0005527 macrolide binding 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0016361 activin receptor activity, type I 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0016362 activin receptor activity, type II 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0016801 hydrolase activity, acting on ether bonds 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0016803 ether hydrolase activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0017002 activin receptor activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0017166 vinculin binding 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0034452 dynactin binding 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0035259 nuclear glucocorticoid receptor binding 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:1990459 transferrin receptor binding 3/3030 12/18639 0.25 1.53787128712871 0.308009994112945 0.635494829783781 GO:0008376 acetylgalactosaminyltransferase activity 7/3030 34/18639 0.205882352941176 1.26648223645894 0.310776241367642 0.639075521220358 GO:0090482 vitamin transmembrane transporter activity 7/3030 34/18639 0.205882352941176 1.26648223645894 0.310776241367642 0.639075521220358 GO:0019842 vitamin binding 27/3030 150/18639 0.18 1.10726732673267 0.31241127507075 0.641374140873724 GO:0050997 quaternary ammonium group binding 8/3030 40/18639 0.2 1.23029702970297 0.320334181811221 0.65546928291405 GO:0071949 FAD binding 8/3030 40/18639 0.2 1.23029702970297 0.320334181811221 0.65546928291405 GO:0005507 copper ion binding 12/3030 63/18639 0.19047619047619 1.17171145685997 0.322303418824093 0.657329341022822 GO:1901682 sulfur compound transmembrane transporter activity 12/3030 63/18639 0.19047619047619 1.17171145685997 0.322303418824093 0.657329341022822 GO:0035250 UDP-galactosyltransferase activity 6/3030 29/18639 0.206896551724138 1.27272106520997 0.328886290397921 0.66855573785807 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 6/3030 29/18639 0.206896551724138 1.27272106520997 0.328886290397921 0.66855573785807 GO:0000400 four-way junction DNA binding 4/3030 18/18639 0.222222222222222 1.36699669966997 0.334055860299707 0.674640499628072 GO:0015172 acidic amino acid transmembrane transporter activity 4/3030 18/18639 0.222222222222222 1.36699669966997 0.334055860299707 0.674640499628072 GO:0016854 racemase and epimerase activity 4/3030 18/18639 0.222222222222222 1.36699669966997 0.334055860299707 0.674640499628072 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 4/3030 18/18639 0.222222222222222 1.36699669966997 0.334055860299707 0.674640499628072 GO:0050431 transforming growth factor beta binding 5/3030 24/18639 0.208333333333333 1.28155940594059 0.349581415819452 0.701521819578601 GO:0060229 lipase activator activity 5/3030 24/18639 0.208333333333333 1.28155940594059 0.349581415819452 0.701521819578601 GO:0070840 dynein complex binding 5/3030 24/18639 0.208333333333333 1.28155940594059 0.349581415819452 0.701521819578601 GO:0015297 antiporter activity 24/3030 135/18639 0.177777777777778 1.09359735973597 0.349696095184404 0.701521819578601 GO:0030695 GTPase regulator activity 83/3030 489/18639 0.169734151329243 1.04411711109761 0.350195166386415 0.701521819578601 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0004535 poly(A)-specific ribonuclease activity 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0005035 death receptor activity 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0005172 vascular endothelial growth factor receptor binding 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0008417 fucosyltransferase activity 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0031994 insulin-like growth factor I binding 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0070123 transforming growth factor beta receptor activity, type III 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0140852 histone ubiquitin ligase activity 3/3030 13/18639 0.230769230769231 1.41957349581112 0.356123181887107 0.702055239332295 GO:0060589 nucleoside-triphosphatase regulator activity 83/3030 490/18639 0.169387755102041 1.04198625985047 0.357765123634502 0.702327064550612 GO:0000149 SNARE binding 19/3030 106/18639 0.179245283018868 1.10262469643191 0.359164115198716 0.702327064550612 GO:0001965 G-protein alpha-subunit binding 6/3030 30/18639 0.2 1.23029702970297 0.359927452624424 0.702327064550612 GO:0001968 fibronectin binding 6/3030 30/18639 0.2 1.23029702970297 0.359927452624424 0.702327064550612 GO:0008187 poly-pyrimidine tract binding 6/3030 30/18639 0.2 1.23029702970297 0.359927452624424 0.702327064550612 GO:0031210 phosphatidylcholine binding 6/3030 30/18639 0.2 1.23029702970297 0.359927452624424 0.702327064550612 GO:0004879 nuclear receptor activity 11/3030 59/18639 0.186440677966102 1.14688706158751 0.360792209773177 0.702327064550612 GO:0036002 pre-mRNA binding 11/3030 59/18639 0.186440677966102 1.14688706158751 0.360792209773177 0.702327064550612 GO:0022853 active monoatomic ion transmembrane transporter activity 21/3030 118/18639 0.177966101694915 1.09475583151535 0.361532167205686 0.702664400211678 GO:0019209 kinase activator activity 26/3030 148/18639 0.175675675675676 1.08066630987423 0.365319712444845 0.708914621958697 GO:0140299 molecular sensor activity 13/3030 71/18639 0.183098591549296 1.12632826662948 0.366530213031629 0.710152287748782 GO:0019894 kinesin binding 8/3030 42/18639 0.19047619047619 1.17171145685997 0.372779387632047 0.715469374612034 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/3030 19/18639 0.210526315789474 1.2950495049505 0.373890447377902 0.715469374612034 GO:0022840 leak channel activity 4/3030 19/18639 0.210526315789474 1.2950495049505 0.373890447377902 0.715469374612034 GO:0022842 narrow pore channel activity 4/3030 19/18639 0.210526315789474 1.2950495049505 0.373890447377902 0.715469374612034 GO:0046624 sphingolipid transporter activity 4/3030 19/18639 0.210526315789474 1.2950495049505 0.373890447377902 0.715469374612034 GO:0050145 nucleoside monophosphate kinase activity 4/3030 19/18639 0.210526315789474 1.2950495049505 0.373890447377902 0.715469374612034 GO:0070003 threonine-type peptidase activity 4/3030 19/18639 0.210526315789474 1.2950495049505 0.373890447377902 0.715469374612034 GO:0097001 ceramide binding 4/3030 19/18639 0.210526315789474 1.2950495049505 0.373890447377902 0.715469374612034 GO:0032266 phosphatidylinositol-3-phosphate binding 9/3030 48/18639 0.1875 1.15340346534653 0.376984960820357 0.720279432075874 GO:1901981 phosphatidylinositol phosphate binding 32/3030 185/18639 0.172972972972973 1.0640406743377 0.379913329581365 0.723235152759321 GO:0003925 G protein activity 10/3030 54/18639 0.185185185185185 1.13916391639164 0.380281709354094 0.723235152759321 GO:0050661 NADP binding 10/3030 54/18639 0.185185185185185 1.13916391639164 0.380281709354094 0.723235152759321 GO:0004709 MAP kinase kinase kinase activity 5/3030 25/18639 0.2 1.23029702970297 0.384318219457901 0.725349455293451 GO:0015645 fatty acid ligase activity 5/3030 25/18639 0.2 1.23029702970297 0.384318219457901 0.725349455293451 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/3030 25/18639 0.2 1.23029702970297 0.384318219457901 0.725349455293451 GO:0042974 nuclear retinoic acid receptor binding 5/3030 25/18639 0.2 1.23029702970297 0.384318219457901 0.725349455293451 GO:0120515 fatty acid-CoA ligase activity 5/3030 25/18639 0.2 1.23029702970297 0.384318219457901 0.725349455293451 GO:0072349 modified amino acid transmembrane transporter activity 6/3030 31/18639 0.193548387096774 1.19061002874481 0.391123745598794 0.736647771102292 GO:0008238 exopeptidase activity 18/3030 102/18639 0.176470588235294 1.08555620267909 0.39159481095483 0.736647771102292 GO:0005496 steroid binding 19/3030 108/18639 0.175925925925926 1.08220572057206 0.392086716877026 0.736647771102292 GO:0004705 JUN kinase activity 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0005161 platelet-derived growth factor receptor binding 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0005545 1-phosphatidylinositol binding 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0016530 metallochaperone activity 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0034236 protein kinase A catalytic subunit binding 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0042043 neurexin family protein binding 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0046030 inositol trisphosphate phosphatase activity 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0098821 BMP receptor activity 3/3030 14/18639 0.214285714285714 1.31817538896747 0.403743463454219 0.747226708482434 GO:0072341 modified amino acid binding 16/3030 91/18639 0.175824175824176 1.08157980633228 0.408398148816923 0.754714909885223 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/3030 20/18639 0.2 1.23029702970297 0.413506553940234 0.759626854645763 GO:0030742 GTP-dependent protein binding 4/3030 20/18639 0.2 1.23029702970297 0.413506553940234 0.759626854645763 GO:0042288 MHC class I protein binding 4/3030 20/18639 0.2 1.23029702970297 0.413506553940234 0.759626854645763 GO:0052745 inositol phosphate phosphatase activity 4/3030 20/18639 0.2 1.23029702970297 0.413506553940234 0.759626854645763 GO:0004435 phosphatidylinositol phospholipase C activity 5/3030 26/18639 0.192307692307692 1.18297791317593 0.418951139886443 0.7650948651829 GO:0004529 DNA exonuclease activity 5/3030 26/18639 0.192307692307692 1.18297791317593 0.418951139886443 0.7650948651829 GO:0005160 transforming growth factor beta receptor binding 5/3030 26/18639 0.192307692307692 1.18297791317593 0.418951139886443 0.7650948651829 GO:0051139 metal cation:proton antiporter activity 5/3030 26/18639 0.192307692307692 1.18297791317593 0.418951139886443 0.7650948651829 GO:0004725 protein tyrosine phosphatase activity 17/3030 98/18639 0.173469387755102 1.06709436249747 0.426241170918324 0.776827734487114 GO:0043178 alcohol binding 16/3030 92/18639 0.173913043478261 1.06982350408954 0.426628779988487 0.776827734487114 GO:0140223 general transcription initiation factor activity 12/3030 68/18639 0.176470588235294 1.08555620267909 0.42747110771038 0.777220195837054 GO:0015399 primary active transmembrane transporter activity 28/3030 166/18639 0.168674698795181 1.03759990456877 0.447564243541584 0.810972539358643 GO:0016846 carbon-sulfur lyase activity 3/3030 15/18639 0.2 1.23029702970297 0.450271141871995 0.810972539358643 GO:0120283 protein serine/threonine kinase binding 3/3030 15/18639 0.2 1.23029702970297 0.450271141871995 0.810972539358643 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/3030 45/18639 0.177777777777778 1.09359735973597 0.452141452356537 0.810972539358643 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 4/3030 21/18639 0.19047619047619 1.17171145685997 0.452539038127888 0.810972539358643 GO:0009975 cyclase activity 4/3030 21/18639 0.19047619047619 1.17171145685997 0.452539038127888 0.810972539358643 GO:0035613 RNA stem-loop binding 4/3030 21/18639 0.19047619047619 1.17171145685997 0.452539038127888 0.810972539358643 GO:0036122 BMP binding 4/3030 21/18639 0.19047619047619 1.17171145685997 0.452539038127888 0.810972539358643 GO:0070182 DNA polymerase binding 4/3030 21/18639 0.19047619047619 1.17171145685997 0.452539038127888 0.810972539358643 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 7/3030 39/18639 0.179487179487179 1.1041127189642 0.4527770472624 0.810972539358643 GO:0008266 poly(U) RNA binding 5/3030 27/18639 0.185185185185185 1.13916391639164 0.4532290078835 0.810972539358643 GO:0097110 scaffold protein binding 12/3030 70/18639 0.171428571428571 1.05454031117397 0.469846744039518 0.839495623355911 GO:0004536 DNA nuclease activity 11/3030 64/18639 0.171875 1.05728650990099 0.471758758087649 0.841699079177963 GO:0030276 clathrin binding 8/3030 46/18639 0.173913043478261 1.06982350408954 0.478308718055572 0.850027542839635 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 15/3030 89/18639 0.168539325842697 1.03676715986205 0.483423497783269 0.850027542839635 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 15/3030 89/18639 0.168539325842697 1.03676715986205 0.483423497783269 0.850027542839635 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 6/3030 34/18639 0.176470588235294 1.08555620267909 0.483712183444326 0.850027542839635 GO:0051119 sugar transmembrane transporter activity 5/3030 28/18639 0.178571428571429 1.09847949080622 0.486928179219182 0.850027542839635 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 5/3030 28/18639 0.178571428571429 1.09847949080622 0.486928179219182 0.850027542839635 GO:0097718 disordered domain specific binding 5/3030 28/18639 0.178571428571429 1.09847949080622 0.486928179219182 0.850027542839635 GO:0008093 cytoskeletal anchor activity 4/3030 22/18639 0.181818181818182 1.11845184518452 0.490675621489665 0.850027542839635 GO:0034062 5'-3' RNA polymerase activity 4/3030 22/18639 0.181818181818182 1.11845184518452 0.490675621489665 0.850027542839635 GO:0097747 RNA polymerase activity 4/3030 22/18639 0.181818181818182 1.11845184518452 0.490675621489665 0.850027542839635 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0004708 MAP kinase kinase activity 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0005024 transforming growth factor beta receptor activity 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0005521 lamin binding 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0015562 efflux transmembrane transporter activity 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0017070 U6 snRNA binding 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0022841 potassium ion leak channel activity 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0022858 alanine transmembrane transporter activity 3/3030 16/18639 0.1875 1.15340346534653 0.49523125539066 0.850027542839635 GO:0045309 protein phosphorylated amino acid binding 10/3030 59/18639 0.169491525423729 1.0426246014432 0.496850431183429 0.850027542839635 GO:0004864 protein phosphatase inhibitor activity 9/3030 53/18639 0.169811320754717 1.04459181767233 0.500298476098647 0.850027542839635 GO:0016251 RNA polymerase II general transcription initiation factor activity 9/3030 53/18639 0.169811320754717 1.04459181767233 0.500298476098647 0.850027542839635 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0005381 iron ion transmembrane transporter activity 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0033204 ribonuclease P RNA binding 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0035256 G protein-coupled glutamate receptor binding 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0043121 neurotrophin binding 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0043208 glycosphingolipid binding 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0070739 protein-glutamic acid ligase activity 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0070740 tubulin-glutamic acid ligase activity 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0141109 transporter activator activity 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:1905394 retromer complex binding 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:1990757 ubiquitin ligase activator activity 2/3030 10/18639 0.2 1.23029702970297 0.501104946625624 0.850027542839635 GO:0140793 histone H2AXY142 phosphatase activity 15/3030 90/18639 0.166666666666667 1.02524752475248 0.502064515772375 0.850491802674515 GO:0035401 histone H3Y41 kinase activity 19/3030 115/18639 0.165217391304348 1.01633232888506 0.508366622555301 0.856797216754638 GO:0140801 histone H2AXY142 kinase activity 19/3030 115/18639 0.165217391304348 1.01633232888506 0.508366622555301 0.856797216754638 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 7/3030 41/18639 0.170731707317073 1.05025356194156 0.50855060607372 0.856797216754638 GO:0015175 neutral L-amino acid transmembrane transporter activity 7/3030 41/18639 0.170731707317073 1.05025356194156 0.50855060607372 0.856797216754638 GO:0004629 phospholipase C activity 5/3030 29/18639 0.172413793103448 1.06060088767497 0.519853572723611 0.874651872696442 GO:0017134 fibroblast growth factor binding 4/3030 23/18639 0.173913043478261 1.06982350408954 0.527656322112062 0.886577018182868 GO:0043539 protein serine/threonine kinase activator activity 12/3030 73/18639 0.164383561643836 1.01120303811203 0.532268862193894 0.893116900027643 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/3030 17/18639 0.176470588235294 1.08555620267909 0.538262403076677 0.898311412940887 GO:0030169 low-density lipoprotein particle binding 3/3030 17/18639 0.176470588235294 1.08555620267909 0.538262403076677 0.898311412940887 GO:0031489 myosin V binding 3/3030 17/18639 0.176470588235294 1.08555620267909 0.538262403076677 0.898311412940887 GO:0038191 neuropilin binding 3/3030 17/18639 0.176470588235294 1.08555620267909 0.538262403076677 0.898311412940887 GO:1902936 phosphatidylinositol bisphosphate binding 18/3030 111/18639 0.162162162162162 0.997538132191598 0.544555432406363 0.907348961170701 GO:0140313 molecular sequestering activity 9/3030 55/18639 0.163636363636364 1.00660666066607 0.547899357072935 0.907348961170701 GO:0016769 transferase activity, transferring nitrogenous groups 5/3030 30/18639 0.166666666666667 1.02524752475248 0.551838796743449 0.907348961170701 GO:0031624 ubiquitin conjugating enzyme binding 5/3030 30/18639 0.166666666666667 1.02524752475248 0.551838796743449 0.907348961170701 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0004016 adenylate cyclase activity 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0004523 RNA-DNA hybrid ribonuclease activity 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0008432 JUN kinase binding 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0032050 clathrin heavy chain binding 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0180030 inositol phosphate kinase activity 2/3030 11/18639 0.181818181818182 1.11845184518452 0.554653639167251 0.907348961170701 GO:0005543 phospholipid binding 80/3030 497/18639 0.160965794768612 0.990178695938004 0.558248111022314 0.912025899430395 GO:0015149 hexose transmembrane transporter activity 4/3030 24/18639 0.166666666666667 1.02524752475248 0.563271303370585 0.91660947005187 GO:0050699 WW domain binding 4/3030 24/18639 0.166666666666667 1.02524752475248 0.563271303370585 0.91660947005187 GO:0055056 D-glucose transmembrane transporter activity 4/3030 24/18639 0.166666666666667 1.02524752475248 0.563271303370585 0.91660947005187 GO:0001618 virus receptor activity 13/3030 81/18639 0.160493827160494 0.987275394206087 0.566863308508669 0.921245743841086 GO:0019212 phosphatase inhibitor activity 9/3030 56/18639 0.160714285714286 0.988631541725601 0.571024554833829 0.926229673788744 GO:0022829 wide pore channel activity 6/3030 37/18639 0.162162162162162 0.997538132191598 0.571423951974507 0.926229673788744 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/3030 18/18639 0.166666666666667 1.02524752475248 0.579103711632071 0.930166583450476 GO:0008308 voltage-gated monoatomic anion channel activity 3/3030 18/18639 0.166666666666667 1.02524752475248 0.579103711632071 0.930166583450476 GO:0008409 5'-3' exonuclease activity 3/3030 18/18639 0.166666666666667 1.02524752475248 0.579103711632071 0.930166583450476 GO:0008525 phosphatidylcholine transporter activity 3/3030 18/18639 0.166666666666667 1.02524752475248 0.579103711632071 0.930166583450476 GO:0017075 syntaxin-1 binding 3/3030 18/18639 0.166666666666667 1.02524752475248 0.579103711632071 0.930166583450476 GO:0031690 adrenergic receptor binding 3/3030 18/18639 0.166666666666667 1.02524752475248 0.579103711632071 0.930166583450476 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/3030 18/18639 0.166666666666667 1.02524752475248 0.579103711632071 0.930166583450476 GO:0005164 tumor necrosis factor receptor binding 5/3030 31/18639 0.161290322580645 0.992175023954008 0.58274553734819 0.932392859757104 GO:0005310 dicarboxylic acid transmembrane transporter activity 5/3030 31/18639 0.161290322580645 0.992175023954008 0.58274553734819 0.932392859757104 GO:0047499 calcium-independent phospholipase A2 activity 5/3030 31/18639 0.161290322580645 0.992175023954008 0.58274553734819 0.932392859757104 GO:0140272 exogenous protein binding 13/3030 82/18639 0.158536585365854 0.975235450374306 0.585807605054261 0.936084317354747 GO:0030020 extracellular matrix structural constituent conferring tensile strength 7/3030 44/18639 0.159090909090909 0.978645364536454 0.58805542493344 0.938466830009608 GO:0030295 protein kinase activator activity 22/3030 139/18639 0.158273381294964 0.9736163544412 0.590390688035817 0.940982587614927 GO:0005096 GTPase activator activity 43/3030 271/18639 0.158671586715867 0.976065909173943 0.595097605903429 0.947267049191595 GO:0000030 mannosyltransferase activity 4/3030 25/18639 0.16 0.984237623762376 0.597357605068239 0.948022957646657 GO:0008483 transaminase activity 4/3030 25/18639 0.16 0.984237623762376 0.597357605068239 0.948022957646657 GO:0000995 RNA polymerase III general transcription initiation factor activity 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0003720 telomerase activity 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0004000 adenosine deaminase activity 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0004126 cytidine deaminase activity 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0005049 nuclear export signal receptor activity 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0005165 neurotrophin receptor binding 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0008179 adenylate cyclase binding 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0016840 carbon-nitrogen lyase activity 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/3030 12/18639 0.166666666666667 1.02524752475248 0.603982368178112 0.948022957646657 GO:0004857 enzyme inhibitor activity 66/3030 416/18639 0.158653846153846 0.975956778370145 0.607308276858902 0.952038259551249 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/3030 32/18639 0.15625 0.961169554455445 0.612462369423909 0.957696517131964 GO:0047498 calcium-dependent phospholipase A2 activity 5/3030 32/18639 0.15625 0.961169554455445 0.612462369423909 0.957696517131964 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/3030 19/18639 0.157894736842105 0.971287128712871 0.617581198679728 0.96206116377244 GO:0008574 plus-end-directed microtubule motor activity 3/3030 19/18639 0.157894736842105 0.971287128712871 0.617581198679728 0.96206116377244 GO:0031420 alkali metal ion binding 3/3030 19/18639 0.157894736842105 0.971287128712871 0.617581198679728 0.96206116377244 GO:0120013 lipid transfer activity 10/3030 65/18639 0.153846153846154 0.946382330540746 0.627437205970011 0.972535465502278 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/3030 26/18639 0.153846153846154 0.946382330540746 0.629795144192201 0.972535465502278 GO:0008198 ferrous iron binding 4/3030 26/18639 0.153846153846154 0.946382330540746 0.629795144192201 0.972535465502278 GO:0015145 monosaccharide transmembrane transporter activity 4/3030 26/18639 0.153846153846154 0.946382330540746 0.629795144192201 0.972535465502278 GO:0030507 spectrin binding 4/3030 26/18639 0.153846153846154 0.946382330540746 0.629795144192201 0.972535465502278 GO:0043548 phosphatidylinositol 3-kinase binding 4/3030 26/18639 0.153846153846154 0.946382330540746 0.629795144192201 0.972535465502278 GO:0050750 low-density lipoprotein particle receptor binding 4/3030 26/18639 0.153846153846154 0.946382330540746 0.629795144192201 0.972535465502278 GO:0001786 phosphatidylserine binding 9/3030 59/18639 0.152542372881356 0.938362141298876 0.637007063102895 0.981486727710769 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 5/3030 33/18639 0.151515151515152 0.932043204320432 0.640903136103352 0.981486727710769 GO:0030296 protein tyrosine kinase activator activity 5/3030 33/18639 0.151515151515152 0.932043204320432 0.640903136103352 0.981486727710769 GO:0016798 hydrolase activity, acting on glycosyl bonds 20/3030 130/18639 0.153846153846154 0.946382330540746 0.643017128081573 0.981486727710769 GO:0002161 aminoacyl-tRNA editing activity 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0003964 RNA-directed DNA polymerase activity 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0008035 high-density lipoprotein particle binding 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0008253 5'-nucleotidase activity 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0017154 semaphorin receptor activity 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0030955 potassium ion binding 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0039706 co-receptor binding 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0043560 insulin receptor substrate binding 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0046974 histone H3K9 methyltransferase activity 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0070700 BMP receptor binding 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0097157 pre-mRNA intronic binding 2/3030 13/18639 0.153846153846154 0.946382330540746 0.649047674776476 0.981486727710769 GO:0052689 carboxylic ester hydrolase activity 14/3030 92/18639 0.152173913043478 0.936095566078347 0.649985114493613 0.981707115678539 GO:0015095 magnesium ion transmembrane transporter activity 3/3030 20/18639 0.15 0.922722772277228 0.653594371280815 0.98595744572775 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 13/3030 86/18639 0.151162790697674 0.929875661984803 0.657688009853891 0.989276642394974 GO:0004683 calcium/calmodulin-dependent protein kinase activity 4/3030 27/18639 0.148148148148148 0.911331133113311 0.660502298332845 0.989276642394974 GO:0015252 proton channel activity 4/3030 27/18639 0.148148148148148 0.911331133113311 0.660502298332845 0.989276642394974 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/3030 27/18639 0.148148148148148 0.911331133113311 0.660502298332845 0.989276642394974 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 4/3030 27/18639 0.148148148148148 0.911331133113311 0.660502298332845 0.989276642394974 GO:0001784 phosphotyrosine residue binding 7/3030 47/18639 0.148936170212766 0.91617863914051 0.660581499921805 0.989276642394974 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 10/3030 67/18639 0.149253731343284 0.918132111718635 0.666819564692148 0.997304322167644 GO:0008013 beta-catenin binding 16/3030 106/18639 0.150943396226415 0.928526060153185 0.667550473708988 0.997304322167644 GO:0004812 aminoacyl-tRNA ligase activity 6/3030 41/18639 0.146341463414634 0.900217338807051 0.675552796588154 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 6/3030 41/18639 0.146341463414634 0.900217338807051 0.675552796588154 1 GO:0008237 metallopeptidase activity 28/3030 184/18639 0.152173913043478 0.936095566078347 0.679707578653919 1 GO:0010314 phosphatidylinositol-5-phosphate binding 3/3030 21/18639 0.142857142857143 0.878783592644979 0.68710359347297 1 GO:0051010 microtubule plus-end binding 3/3030 21/18639 0.142857142857143 0.878783592644979 0.68710359347297 1 GO:0005313 L-glutamate transmembrane transporter activity 2/3030 14/18639 0.142857142857143 0.878783592644979 0.689931709996852 1 GO:0008559 ABC-type xenobiotic transporter activity 2/3030 14/18639 0.142857142857143 0.878783592644979 0.689931709996852 1 GO:0015386 potassium:proton antiporter activity 2/3030 14/18639 0.142857142857143 0.878783592644979 0.689931709996852 1 GO:0015926 glucosidase activity 2/3030 14/18639 0.142857142857143 0.878783592644979 0.689931709996852 1 GO:0071933 Arp2/3 complex binding 2/3030 14/18639 0.142857142857143 0.878783592644979 0.689931709996852 1 GO:1901612 cardiolipin binding 2/3030 14/18639 0.142857142857143 0.878783592644979 0.689931709996852 1 GO:0004623 phospholipase A2 activity 5/3030 35/18639 0.142857142857143 0.878783592644979 0.693726447618664 1 GO:0016229 steroid dehydrogenase activity 5/3030 35/18639 0.142857142857143 0.878783592644979 0.693726447618664 1 GO:1901681 sulfur compound binding 42/3030 275/18639 0.152727272727273 0.939499549954996 0.696534196796242 1 GO:0004520 DNA endonuclease activity 6/3030 42/18639 0.142857142857143 0.878783592644979 0.698860787725838 1 GO:0030170 pyridoxal phosphate binding 8/3030 56/18639 0.142857142857143 0.878783592644979 0.709956845418715 1 GO:0004190 aspartic-type endopeptidase activity 5/3030 36/18639 0.138888888888889 0.854372937293729 0.718044824833247 1 GO:0008970 phospholipase A1 activity 3/3030 22/18639 0.136363636363636 0.838838883888389 0.718118536417702 1 GO:0015377 chloride:monoatomic cation symporter activity 3/3030 22/18639 0.136363636363636 0.838838883888389 0.718118536417702 1 GO:0003779 actin binding 68/3030 443/18639 0.153498871331828 0.944246027311535 0.718771569477595 1 GO:0016782 transferase activity, transferring sulphur-containing groups 10/3030 70/18639 0.142857142857143 0.878783592644979 0.721103218587447 1 GO:0044325 transmembrane transporter binding 20/3030 136/18639 0.147058823529412 0.904630168899243 0.722975196481293 1 GO:0004129 cytochrome-c oxidase activity 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0004559 alpha-mannosidase activity 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0008242 omega peptidase activity 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0008252 nucleotidase activity 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0031386 protein tag activity 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0045504 dynein heavy chain binding 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0141047 molecular tag activity 2/3030 15/18639 0.133333333333333 0.82019801980198 0.726802566631446 1 GO:0070279 vitamin B6 binding 8/3030 57/18639 0.140350877192982 0.863366336633663 0.728950947983745 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 13/3030 91/18639 0.142857142857143 0.878783592644979 0.737046154674288 1 GO:0030246 carbohydrate binding 42/3030 280/18639 0.15 0.922722772277228 0.740647307243394 1 GO:0023023 MHC protein complex binding 5/3030 37/18639 0.135135135135135 0.831281776826331 0.740954336217425 1 GO:0070001 aspartic-type peptidase activity 5/3030 37/18639 0.135135135135135 0.831281776826331 0.740954336217425 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/3030 30/18639 0.133333333333333 0.82019801980198 0.741906059107504 1 GO:0033612 receptor serine/threonine kinase binding 4/3030 30/18639 0.133333333333333 0.82019801980198 0.741906059107504 1 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:0004602 glutathione peroxidase activity 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:0005212 structural constituent of eye lens 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:0016849 phosphorus-oxygen lyase activity 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:0031681 G-protein beta-subunit binding 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:0099186 structural constituent of postsynapse 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/3030 23/18639 0.130434782608696 0.802367628067154 0.746687868563548 1 GO:0005149 interleukin-1 receptor binding 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0015378 sodium:chloride symporter activity 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0015385 sodium:proton antiporter activity 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0015923 mannosidase activity 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0016722 oxidoreductase activity, acting on metal ions 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0140327 flippase activity 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0140328 floppase activity 2/3030 16/18639 0.125 0.768935643564356 0.759884182522987 1 GO:0016209 antioxidant activity 12/3030 86/18639 0.13953488372093 0.858346764909049 0.761366657725613 1 GO:0042887 amide transmembrane transporter activity 5/3030 38/18639 0.131578947368421 0.809405940594059 0.762463711189748 1 GO:0070273 phosphatidylinositol-4-phosphate binding 4/3030 31/18639 0.129032258064516 0.793740019163207 0.76548539566444 1 GO:0070325 lipoprotein particle receptor binding 4/3030 31/18639 0.129032258064516 0.793740019163207 0.76548539566444 1 GO:0003774 cytoskeletal motor activity 22/3030 153/18639 0.143790849673203 0.884527276257037 0.767549964651105 1 GO:0048306 calcium-dependent protein binding 11/3030 80/18639 0.1375 0.845829207920792 0.772186828654611 1 GO:0004806 triacylglycerol lipase activity 3/3030 24/18639 0.125 0.768935643564356 0.772890235019685 1 GO:0005315 phosphate transmembrane transporter activity 3/3030 24/18639 0.125 0.768935643564356 0.772890235019685 1 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/3030 24/18639 0.125 0.768935643564356 0.772890235019685 1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/3030 24/18639 0.125 0.768935643564356 0.772890235019685 1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/3030 24/18639 0.125 0.768935643564356 0.772890235019685 1 GO:0070300 phosphatidic acid binding 3/3030 24/18639 0.125 0.768935643564356 0.772890235019685 1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/3030 24/18639 0.125 0.768935643564356 0.772890235019685 1 GO:0008081 phosphoric diester hydrolase activity 12/3030 87/18639 0.137931034482759 0.848480710139979 0.775256791243101 1 GO:0031406 carboxylic acid binding 27/3030 187/18639 0.144385026737968 0.888182347646529 0.778738921797705 1 GO:0042910 xenobiotic transmembrane transporter activity 4/3030 32/18639 0.125 0.768935643564356 0.787345827984516 1 GO:0043425 bHLH transcription factor binding 4/3030 32/18639 0.125 0.768935643564356 0.787345827984516 1 GO:0071813 lipoprotein particle binding 4/3030 32/18639 0.125 0.768935643564356 0.787345827984516 1 GO:0071814 protein-lipid complex binding 4/3030 32/18639 0.125 0.768935643564356 0.787345827984516 1 GO:0120015 sterol transfer activity 4/3030 32/18639 0.125 0.768935643564356 0.787345827984516 1 GO:0005092 GDP-dissociation inhibitor activity 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0016018 cyclosporin A binding 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0017110 nucleoside diphosphate phosphatase activity 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0036041 long-chain fatty acid binding 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0046965 nuclear retinoid X receptor binding 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0070403 NAD+ binding 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0070492 oligosaccharide binding 2/3030 17/18639 0.117647058823529 0.723704135119394 0.789433753115828 1 GO:0015271 outward rectifier potassium channel activity 3/3030 25/18639 0.12 0.738178217821782 0.796826502740337 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/3030 25/18639 0.12 0.738178217821782 0.796826502740337 1 GO:0120020 cholesterol transfer activity 3/3030 25/18639 0.12 0.738178217821782 0.796826502740337 1 GO:0003777 microtubule motor activity 9/3030 68/18639 0.132352941176471 0.814167152009319 0.796838859446624 1 GO:0043177 organic acid binding 27/3030 189/18639 0.142857142857143 0.878783592644979 0.796903439517262 1 GO:0140359 ABC-type transporter activity 6/3030 47/18639 0.127659574468085 0.785295976406151 0.79808066193269 1 GO:0015144 carbohydrate transmembrane transporter activity 5/3030 40/18639 0.125 0.768935643564356 0.801377047266895 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 18/3030 130/18639 0.138461538461538 0.851744097486672 0.805189611373886 1 GO:0000900 mRNA regulatory element binding translation repressor activity 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0004706 JUN kinase kinase kinase activity 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0015373 monoatomic anion:sodium symporter activity 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0030228 lipoprotein particle receptor activity 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0050811 GABA receptor binding 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0098641 cadherin binding involved in cell-cell adhesion 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:1901611 phosphatidylglycerol binding 2/3030 18/18639 0.111111111111111 0.683498349834983 0.815725008301298 1 GO:0005319 lipid transporter activity 25/3030 178/18639 0.140449438202247 0.863972633218378 0.816412494483963 1 GO:0005112 Notch binding 3/3030 26/18639 0.115384615384615 0.70978674790556 0.818613201681399 1 GO:0042287 MHC protein binding 5/3030 41/18639 0.121951219512195 0.750181115672543 0.818852637638942 1 GO:0140828 metal cation:monoatomic cation antiporter activity 5/3030 41/18639 0.121951219512195 0.750181115672543 0.818852637638942 1 GO:0051427 hormone receptor binding 4/3030 34/18639 0.117647058823529 0.723704135119394 0.826150126031496 1 GO:0070851 growth factor receptor binding 19/3030 139/18639 0.136690647482014 0.840850487926491 0.82717423554102 1 GO:0061134 peptidase regulator activity 32/3030 226/18639 0.141592920353982 0.871006746692368 0.828634367510159 1 GO:0035254 glutamate receptor binding 6/3030 49/18639 0.122448979591837 0.753243079409982 0.829902383119751 1 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0004090 carbonyl reductase (NADPH) activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0005345 purine nucleobase transmembrane transporter activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0008239 dipeptidyl-peptidase activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0008519 ammonium channel activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0015187 glycine transmembrane transporter activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0015643 toxic substance binding 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0019911 structural constituent of myelin sheath 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0031434 mitogen-activated protein kinase kinase binding 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0031996 thioesterase binding 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0035374 chondroitin sulfate binding 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:1990763 arrestin family protein binding 1/3030 10/18639 0.1 0.615148514851485 0.830440896892369 1 GO:0033218 amide binding 35/3030 247/18639 0.1417004048583 0.871667936024372 0.83673693291576 1 GO:0008301 DNA binding, bending 2/3030 19/18639 0.105263157894737 0.647524752475248 0.839036044727365 1 GO:0015245 fatty acid transmembrane transporter activity 2/3030 19/18639 0.105263157894737 0.647524752475248 0.839036044727365 1 GO:0022821 solute:potassium antiporter activity 2/3030 19/18639 0.105263157894737 0.647524752475248 0.839036044727365 1 GO:0042834 peptidoglycan binding 2/3030 19/18639 0.105263157894737 0.647524752475248 0.839036044727365 1 GO:0005506 iron ion binding 21/3030 154/18639 0.136363636363636 0.838838883888389 0.840137476422314 1 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 38/3030 268/18639 0.141791044776119 0.872225506132703 0.844382080889048 1 GO:0033293 monocarboxylic acid binding 10/3030 79/18639 0.126582278481013 0.778669006141121 0.847249648255558 1 GO:0046875 ephrin receptor binding 3/3030 28/18639 0.107142857142857 0.659087694483734 0.856250554169749 1 GO:0050698 proteoglycan sulfotransferase activity 3/3030 28/18639 0.107142857142857 0.659087694483734 0.856250554169749 1 GO:0003953 NAD+ nucleosidase activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0005114 type II transforming growth factor beta receptor binding 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0008046 axon guidance receptor activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0015173 aromatic amino acid transmembrane transporter activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0015205 nucleobase transmembrane transporter activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0019206 nucleoside kinase activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0019215 intermediate filament binding 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0019864 IgG binding 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0042608 T cell receptor binding 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0070697 activin receptor binding 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0097493 structural molecule activity conferring elasticity 1/3030 11/18639 0.0909090909090909 0.559225922592259 0.858019622664881 1 GO:0004033 aldo-keto reductase (NADPH) activity 4/3030 36/18639 0.111111111111111 0.683498349834983 0.858886080708946 1 GO:0045505 dynein intermediate chain binding 4/3030 36/18639 0.111111111111111 0.683498349834983 0.858886080708946 1 GO:0001972 retinoic acid binding 2/3030 20/18639 0.1 0.615148514851485 0.859640675110315 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/3030 20/18639 0.1 0.615148514851485 0.859640675110315 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/3030 20/18639 0.1 0.615148514851485 0.859640675110315 1 GO:0001217 DNA-binding transcription repressor activity 39/3030 278/18639 0.140287769784173 0.862978132345608 0.864429948997745 1 GO:0004620 phospholipase activity 14/3030 109/18639 0.128440366972477 0.79009900990099 0.86577153593144 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 6/3030 52/18639 0.115384615384615 0.70978674790556 0.869957386048423 1 GO:0043236 laminin binding 3/3030 29/18639 0.103448275862069 0.636360532604985 0.872368261482532 1 GO:0141110 transporter inhibitor activity 5/3030 45/18639 0.111111111111111 0.683498349834983 0.876689593328801 1 GO:0008373 sialyltransferase activity 2/3030 21/18639 0.0952380952380952 0.585855728429986 0.877802473177404 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/3030 21/18639 0.0952380952380952 0.585855728429986 0.877802473177404 1 GO:0061891 calcium ion sensor activity 2/3030 21/18639 0.0952380952380952 0.585855728429986 0.877802473177404 1 GO:0004032 aldose reductase (NADPH) activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0004859 phospholipase inhibitor activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0005436 sodium:phosphate symporter activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0008603 cAMP-dependent protein kinase regulator activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0015368 calcium:monoatomic cation antiporter activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0016208 AMP binding 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0016423 tRNA (guanine) methyltransferase activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0035497 cAMP response element binding 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0070410 co-SMAD binding 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0097677 STAT family protein binding 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0140900 chloride:bicarbonate antiporter activity 1/3030 12/18639 0.0833333333333333 0.512623762376238 0.881113918527314 1 GO:0005501 retinoid binding 4/3030 38/18639 0.105263157894737 0.647524752475248 0.886206381902569 1 GO:0019840 isoprenoid binding 4/3030 38/18639 0.105263157894737 0.647524752475248 0.886206381902569 1 GO:0098918 structural constituent of synapse 3/3030 30/18639 0.1 0.615148514851485 0.886864061746424 1 GO:0033691 sialic acid binding 2/3030 22/18639 0.0909090909090909 0.559225922592259 0.893770866853374 1 GO:0140784 metal ion sensor activity 2/3030 22/18639 0.0909090909090909 0.559225922592259 0.893770866853374 1 GO:0005504 fatty acid binding 5/3030 47/18639 0.106382978723404 0.654413313671793 0.899170954928461 1 GO:0005542 folic acid binding 1/3030 13/18639 0.0769230769230769 0.473191165270373 0.900452772173217 1 GO:0035325 Toll-like receptor binding 1/3030 13/18639 0.0769230769230769 0.473191165270373 0.900452772173217 1 GO:0035673 oligopeptide transmembrane transporter activity 1/3030 13/18639 0.0769230769230769 0.473191165270373 0.900452772173217 1 GO:0045159 myosin II binding 1/3030 13/18639 0.0769230769230769 0.473191165270373 0.900452772173217 1 GO:0089720 caspase binding 1/3030 13/18639 0.0769230769230769 0.473191165270373 0.900452772173217 1 GO:0005283 amino acid:sodium symporter activity 2/3030 23/18639 0.0869565217391304 0.53491175204477 0.907778771452405 1 GO:0016493 C-C chemokine receptor activity 2/3030 23/18639 0.0869565217391304 0.53491175204477 0.907778771452405 1 GO:0043274 phospholipase binding 2/3030 23/18639 0.0869565217391304 0.53491175204477 0.907778771452405 1 GO:0019955 cytokine binding 18/3030 144/18639 0.125 0.768935643564356 0.913676680238313 1 GO:0016298 lipase activity 16/3030 130/18639 0.123076923076923 0.757105864432597 0.914591763705453 1 GO:0008191 metalloendopeptidase inhibitor activity 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0019763 immunoglobulin receptor activity 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0031404 chloride ion binding 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0044548 S100 protein binding 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0061665 SUMO ligase activity 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0070742 C2H2 zinc finger domain binding 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:1901474 azole transmembrane transporter activity 1/3030 14/18639 0.0714285714285714 0.439391796322489 0.916646700032938 1 GO:0004622 lysophospholipase activity 2/3030 24/18639 0.0833333333333333 0.512623762376238 0.920041365673561 1 GO:0005540 hyaluronic acid binding 2/3030 24/18639 0.0833333333333333 0.512623762376238 0.920041365673561 1 GO:0019957 C-C chemokine binding 2/3030 24/18639 0.0833333333333333 0.512623762376238 0.920041365673561 1 GO:0030552 cAMP binding 2/3030 24/18639 0.0833333333333333 0.512623762376238 0.920041365673561 1 GO:0038024 cargo receptor activity 7/3030 65/18639 0.107692307692308 0.662467631378522 0.921158733697787 1 GO:0019956 chemokine binding 3/3030 33/18639 0.0909090909090909 0.559225922592259 0.921905680429006 1 GO:0004089 carbonate dehydratase activity 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0005041 low-density lipoprotein particle receptor activity 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0005523 tropomyosin binding 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0031005 filamin binding 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0048531 beta-1,3-galactosyltransferase activity 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0050780 dopamine receptor binding 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0051371 muscle alpha-actinin binding 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0140161 monocarboxylate:sodium symporter activity 1/3030 15/18639 0.0666666666666667 0.41009900990099 0.930206995275901 1 GO:0005537 D-mannose binding 2/3030 25/18639 0.08 0.492118811881188 0.930755701580798 1 GO:0015020 glucuronosyltransferase activity 3/3030 34/18639 0.0882352941176471 0.542778101339546 0.931172346983603 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/3030 34/18639 0.0882352941176471 0.542778101339546 0.931172346983603 1 GO:0005010 insulin-like growth factor receptor activity 5/3030 51/18639 0.0980392156862745 0.603086779266162 0.933658077890231 1 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/3030 59/18639 0.101694915254237 0.625574760865917 0.933684261022033 1 GO:0050840 extracellular matrix binding 7/3030 67/18639 0.104477611940299 0.642692478203044 0.934685344292932 1 GO:0008200 ion channel inhibitor activity 4/3030 43/18639 0.0930232558139535 0.572231176606033 0.935215504813794 1 GO:0001637 G protein-coupled chemoattractant receptor activity 2/3030 26/18639 0.0769230769230769 0.473191165270373 0.940100909905748 1 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/3030 26/18639 0.0769230769230769 0.473191165270373 0.940100909905748 1 GO:0004950 chemokine receptor activity 2/3030 26/18639 0.0769230769230769 0.473191165270373 0.940100909905748 1 GO:0008157 protein phosphatase 1 binding 2/3030 26/18639 0.0769230769230769 0.473191165270373 0.940100909905748 1 GO:0019841 retinol binding 1/3030 16/18639 0.0625 0.384467821782178 0.941561849459429 1 GO:0055102 lipase inhibitor activity 1/3030 16/18639 0.0625 0.384467821782178 0.941561849459429 1 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/3030 16/18639 0.0625 0.384467821782178 0.941561849459429 1 GO:0016248 channel inhibitor activity 4/3030 44/18639 0.0909090909090909 0.559225922592259 0.942344162022196 1 GO:0017046 peptide hormone binding 5/3030 53/18639 0.0943396226415094 0.580328787595741 0.946581341039393 1 GO:0005044 scavenger receptor activity 2/3030 27/18639 0.0740740740740741 0.455665566556656 0.94823881753021 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/3030 27/18639 0.0740740740740741 0.455665566556656 0.94823881753021 1 GO:0035255 ionotropic glutamate receptor binding 2/3030 27/18639 0.0740740740740741 0.455665566556656 0.94823881753021 1 GO:0051015 actin filament binding 26/3030 209/18639 0.124401913875598 0.765256525652565 0.949031726966008 1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/3030 17/18639 0.0588235294117647 0.361852067559697 0.951069855480904 1 GO:0008569 minus-end-directed microtubule motor activity 1/3030 17/18639 0.0588235294117647 0.361852067559697 0.951069855480904 1 GO:0015278 intracellularly gated calcium channel activity 1/3030 17/18639 0.0588235294117647 0.361852067559697 0.951069855480904 1 GO:0019198 transmembrane receptor protein phosphatase activity 1/3030 17/18639 0.0588235294117647 0.361852067559697 0.951069855480904 1 GO:0045125 bioactive lipid receptor activity 1/3030 17/18639 0.0588235294117647 0.361852067559697 0.951069855480904 1 GO:0045236 CXCR chemokine receptor binding 1/3030 17/18639 0.0588235294117647 0.361852067559697 0.951069855480904 1 GO:0015179 L-amino acid transmembrane transporter activity 6/3030 62/18639 0.0967741935483871 0.595305014372405 0.95118674751507 1 GO:0019199 transmembrane receptor protein kinase activity 8/3030 78/18639 0.102564102564103 0.630921553693831 0.951721795376643 1 GO:0030551 cyclic nucleotide binding 3/3030 37/18639 0.0810810810810811 0.498769066095799 0.953227476136993 1 GO:0042562 hormone binding 10/3030 94/18639 0.106382978723404 0.654413313671793 0.953978475674523 1 GO:0004180 carboxypeptidase activity 4/3030 46/18639 0.0869565217391304 0.53491175204477 0.954495468402648 1 GO:0005178 integrin binding 19/3030 161/18639 0.118012422360248 0.72595166348933 0.954923216290635 1 GO:0051393 alpha-actinin binding 2/3030 28/18639 0.0714285714285714 0.439391796322489 0.955314837788707 1 GO:0051959 dynein light intermediate chain binding 2/3030 28/18639 0.0714285714285714 0.439391796322489 0.955314837788707 1 GO:0004222 metalloendopeptidase activity 12/3030 110/18639 0.109090909090909 0.671071107110711 0.956982000980659 1 GO:0000146 microfilament motor activity 3/3030 38/18639 0.0789473684210526 0.485643564356436 0.958972141357086 1 GO:0034185 apolipoprotein binding 1/3030 18/18639 0.0555555555555556 0.341749174917492 0.959031317079704 1 GO:0099602 neurotransmitter receptor regulator activity 1/3030 18/18639 0.0555555555555556 0.341749174917492 0.959031317079704 1 GO:0005416 amino acid:monoatomic cation symporter activity 2/3030 29/18639 0.0689655172413793 0.42424035506999 0.961459028626202 1 GO:0005516 calmodulin binding 25/3030 207/18639 0.120772946859903 0.742932988951069 0.962670852532049 1 GO:0015101 organic cation transmembrane transporter activity 8/3030 81/18639 0.0987654320987654 0.607554088742208 0.963729059998251 1 GO:0046982 protein heterodimerization activity 48/3030 369/18639 0.130081300813008 0.800193190050713 0.965386746672894 1 GO:0008381 mechanosensitive monoatomic ion channel activity 1/3030 19/18639 0.0526315789473684 0.323762376237624 0.965697721099279 1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/3030 19/18639 0.0526315789473684 0.323762376237624 0.965697721099279 1 GO:0016918 retinal binding 1/3030 19/18639 0.0526315789473684 0.323762376237624 0.965697721099279 1 GO:0030506 ankyrin binding 1/3030 19/18639 0.0526315789473684 0.323762376237624 0.965697721099279 1 GO:0043395 heparan sulfate proteoglycan binding 1/3030 19/18639 0.0526315789473684 0.323762376237624 0.965697721099279 1 GO:0004601 peroxidase activity 5/3030 57/18639 0.087719298245614 0.53960396039604 0.96582236017484 1 GO:0004175 endopeptidase activity 53/3030 405/18639 0.130864197530864 0.805009167583425 0.968125911381696 1 GO:0005004 GPI-linked ephrin receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0005008 hepatocyte growth factor receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0005009 insulin receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0005011 macrophage colony-stimulating factor receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0005020 stem cell factor receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0008288 boss receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0036332 placental growth factor receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0038062 protein tyrosine kinase collagen receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0060175 brain-derived neurotrophic factor receptor activity 4/3030 49/18639 0.0816326530612245 0.502162052939988 0.968354920476939 1 GO:0005452 solute:inorganic anion antiporter activity 2/3030 31/18639 0.0645161290322581 0.396870009581603 0.9714022972165 1 GO:0017147 Wnt-protein binding 2/3030 31/18639 0.0645161290322581 0.396870009581603 0.9714022972165 1 GO:0005006 epidermal growth factor receptor activity 4/3030 50/18639 0.08 0.492118811881188 0.972020649976448 1 GO:0005007 fibroblast growth factor receptor activity 4/3030 50/18639 0.08 0.492118811881188 0.972020649976448 1 GO:0005017 platelet-derived growth factor receptor activity 4/3030 50/18639 0.08 0.492118811881188 0.972020649976448 1 GO:0005019 platelet-derived growth factor beta-receptor activity 4/3030 50/18639 0.08 0.492118811881188 0.972020649976448 1 GO:0070888 E-box binding 5/3030 59/18639 0.0847457627118644 0.521312300721598 0.97282885126331 1 GO:0017022 myosin binding 7/3030 76/18639 0.0921052631578947 0.566584158415842 0.973385457719832 1 GO:0022804 active transmembrane transporter activity 60/3030 457/18639 0.131291028446389 0.807634811621206 0.973729749686852 1 GO:0042277 peptide binding 30/3030 249/18639 0.120481927710843 0.741142788977693 0.974764439942199 1 GO:0005021 vascular endothelial growth factor receptor activity 4/3030 51/18639 0.0784313725490196 0.482469423412929 0.975285549728467 1 GO:0005030 neurotrophin receptor activity 4/3030 51/18639 0.0784313725490196 0.482469423412929 0.975285549728467 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/3030 60/18639 0.0833333333333333 0.512623762376238 0.975808076731571 1 GO:0001846 opsonin binding 1/3030 21/18639 0.0476190476190476 0.292927864214993 0.97595353077371 1 GO:0005248 voltage-gated sodium channel activity 1/3030 21/18639 0.0476190476190476 0.292927864214993 0.97595353077371 1 GO:0051428 peptide hormone receptor binding 1/3030 21/18639 0.0476190476190476 0.292927864214993 0.97595353077371 1 GO:0008307 structural constituent of muscle 3/3030 42/18639 0.0714285714285714 0.439391796322489 0.975954131421592 1 GO:0042056 chemoattractant activity 3/3030 42/18639 0.0714285714285714 0.439391796322489 0.975954131421592 1 GO:0015026 coreceptor activity 5/3030 61/18639 0.0819672131147541 0.504220094140562 0.978480383767932 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/3030 22/18639 0.0454545454545455 0.27961296129613 0.979866990960393 1 GO:0005003 ephrin receptor activity 4/3030 53/18639 0.0754716981132075 0.464263030076593 0.980770064267963 1 GO:0005005 transmembrane-ephrin receptor activity 4/3030 53/18639 0.0754716981132075 0.464263030076593 0.980770064267963 1 GO:0005246 calcium channel regulator activity 4/3030 53/18639 0.0754716981132075 0.464263030076593 0.980770064267963 1 GO:0005544 calcium-dependent phospholipid binding 4/3030 53/18639 0.0754716981132075 0.464263030076593 0.980770064267963 1 GO:0008146 sulfotransferase activity 4/3030 53/18639 0.0754716981132075 0.464263030076593 0.980770064267963 1 GO:0038064 collagen receptor activity 4/3030 53/18639 0.0754716981132075 0.464263030076593 0.980770064267963 1 GO:0005126 cytokine receptor binding 33/3030 275/18639 0.12 0.738178217821782 0.98093074463358 1 GO:0005200 structural constituent of cytoskeleton 11/3030 112/18639 0.0982142857142857 0.604163719943423 0.981573269055227 1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/3030 23/18639 0.0434782608695652 0.267455876022385 0.983143728210756 1 GO:0005343 organic acid:sodium symporter activity 2/3030 35/18639 0.0571428571428571 0.351513437057991 0.984395980743682 1 GO:0042626 ATPase-coupled transmembrane transporter activity 9/3030 98/18639 0.0918367346938776 0.564932309557486 0.984934035046368 1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/3030 24/18639 0.0416666666666667 0.256311881188119 0.985887309190634 1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/3030 24/18639 0.0416666666666667 0.256311881188119 0.985887309190634 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/3030 24/18639 0.0416666666666667 0.256311881188119 0.985887309190634 1 GO:0030215 semaphorin receptor binding 1/3030 24/18639 0.0416666666666667 0.256311881188119 0.985887309190634 1 GO:0030165 PDZ domain binding 7/3030 83/18639 0.0843373493975904 0.518799952284385 0.987408991283743 1 GO:0001848 complement binding 1/3030 25/18639 0.04 0.246059405940594 0.98818445950771 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/3030 25/18639 0.04 0.246059405940594 0.98818445950771 1 GO:0042805 actinin binding 2/3030 37/18639 0.0540540540540541 0.332512710730533 0.988518844176682 1 GO:0043394 proteoglycan binding 2/3030 37/18639 0.0540540540540541 0.332512710730533 0.988518844176682 1 GO:0038187 pattern recognition receptor activity 3/3030 48/18639 0.0625 0.384467821782178 0.98948928213501 1 GO:0019865 immunoglobulin binding 1/3030 26/18639 0.0384615384615385 0.236595582635187 0.990107801491789 1 GO:0030247 polysaccharide binding 1/3030 26/18639 0.0384615384615385 0.236595582635187 0.990107801491789 1 GO:0005201 extracellular matrix structural constituent 17/3030 168/18639 0.101190476190476 0.62247171145686 0.991623862548261 1 GO:0023026 MHC class II protein complex binding 1/3030 27/18639 0.037037037037037 0.227832783278328 0.991718147028773 1 GO:0004896 cytokine receptor activity 8/3030 96/18639 0.0833333333333333 0.512623762376238 0.99224606989471 1 GO:0005242 inward rectifier potassium channel activity 1/3030 28/18639 0.0357142857142857 0.219695898161245 0.993066417741368 1 GO:0045499 chemorepellent activity 1/3030 28/18639 0.0357142857142857 0.219695898161245 0.993066417741368 1 GO:0016597 amino acid binding 3/3030 51/18639 0.0588235294117647 0.361852067559697 0.993119673634056 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 60/3030 484/18639 0.12396694214876 0.762580803534899 0.993169811458778 1 GO:0008514 organic anion transmembrane transporter activity 30/3030 269/18639 0.111524163568773 0.68603923589385 0.993227124479468 1 GO:0001530 lipopolysaccharide binding 2/3030 41/18639 0.0487804878048781 0.300072446269017 0.993825810960779 1 GO:0004181 metallocarboxypeptidase activity 1/3030 29/18639 0.0344827586206897 0.212120177534995 0.994195253066909 1 GO:0099604 ligand-gated calcium channel activity 1/3030 29/18639 0.0344827586206897 0.212120177534995 0.994195253066909 1 GO:0015291 secondary active transmembrane transporter activity 32/3030 287/18639 0.111498257839721 0.685879877186325 0.99458554378682 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/3030 30/18639 0.0333333333333333 0.205049504950495 0.995140356946934 1 GO:0001216 DNA-binding transcription activator activity 60/3030 491/18639 0.122199592668024 0.751708979451917 0.995332469639232 1 GO:0001540 amyloid-beta binding 6/3030 83/18639 0.072289156626506 0.444685673386616 0.995463316262091 1 GO:0005245 voltage-gated calcium channel activity 2/3030 43/18639 0.0465116279069767 0.286115588303016 0.995485729889961 1 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/3030 54/18639 0.0555555555555556 0.341749174917492 0.995521905536846 1 GO:0061135 endopeptidase regulator activity 18/3030 184/18639 0.0978260869565217 0.601775721050366 0.995839117550766 1 GO:0003730 mRNA 3'-UTR binding 28/3030 262/18639 0.106870229007634 0.657410626558839 0.996184414394857 1 GO:0015106 bicarbonate transmembrane transporter activity 1/3030 32/18639 0.03125 0.192233910891089 0.996594091985635 1 GO:0170055 lipid transmembrane transporter activity 3/3030 56/18639 0.0535714285714286 0.329543847241867 0.996646613498756 1 GO:0042605 peptide antigen binding 2/3030 45/18639 0.0444444444444444 0.273399339933993 0.996705214439687 1 GO:0005539 glycosaminoglycan binding 25/3030 242/18639 0.103305785123967 0.635484002945749 0.996924382858648 1 GO:0016500 protein-hormone receptor activity 4/3030 67/18639 0.0597014925373134 0.367252844687454 0.996956050681584 1 GO:0140375 immune receptor activity 14/3030 156/18639 0.0897435897435897 0.552056359482102 0.997149063220493 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/3030 46/18639 0.0434782608695652 0.267455876022385 0.997186949311334 1 GO:0015459 potassium channel regulator activity 3/3030 59/18639 0.0508474576271186 0.312787380432959 0.997835657169305 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/3030 70/18639 0.0571428571428571 0.351513437057991 0.997982805638031 1 GO:0046906 tetrapyrrole binding 13/3030 152/18639 0.0855263157894737 0.526113861386139 0.998133831784829 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/3030 36/18639 0.0277777777777778 0.170874587458746 0.998327232742172 1 GO:0048020 CCR chemokine receptor binding 2/3030 50/18639 0.04 0.246059405940594 0.998510861801258 1 GO:0015171 amino acid transmembrane transporter activity 7/3030 102/18639 0.0686274509803922 0.422160745486313 0.998612909348582 1 GO:0008201 heparin binding 15/3030 172/18639 0.0872093023255814 0.536466728068156 0.998657083334543 1 GO:0005272 sodium channel activity 2/3030 51/18639 0.0392156862745098 0.241234711706465 0.998730910297878 1 GO:0005109 frizzled binding 1/3030 38/18639 0.0263157894736842 0.161881188118812 0.998827778799385 1 GO:0004867 serine-type endopeptidase inhibitor activity 6/3030 95/18639 0.0631578947368421 0.388514851485149 0.998983161534154 1 GO:0098631 cell adhesion mediator activity 4/3030 76/18639 0.0526315789473684 0.323762376237624 0.99912656759869 1 GO:0141108 transporter regulator activity 14/3030 170/18639 0.0823529411764706 0.506592894583576 0.999294648836124 1 GO:0098632 cell-cell adhesion mediator activity 2/3030 55/18639 0.0363636363636364 0.223690369036904 0.999332663074806 1 GO:0015370 solute:sodium symporter activity 4/3030 79/18639 0.0506329113924051 0.311467602456448 0.999428932929654 1 GO:0030547 signaling receptor inhibitor activity 1/3030 44/18639 0.0227272727272727 0.139806480648065 0.999596705147655 1 GO:0005253 monoatomic anion channel activity 6/3030 103/18639 0.058252427184466 0.358338940690186 0.999640100623979 1 GO:0016247 channel regulator activity 13/3030 168/18639 0.0773809523809524 0.476007779349364 0.999649663705066 1 GO:0008009 chemokine activity 1/3030 45/18639 0.0222222222222222 0.136699669966997 0.999662420845563 1 GO:0020037 heme binding 10/3030 142/18639 0.0704225352112676 0.433203179472877 0.999679888987973 1 GO:0030414 peptidase inhibitor activity 13/3030 169/18639 0.0769230769230769 0.473191165270373 0.999685609108941 1 GO:0042379 chemokine receptor binding 3/3030 72/18639 0.0416666666666667 0.256311881188119 0.999690274805685 1 GO:0004866 endopeptidase inhibitor activity 12/3030 161/18639 0.0745341614906832 0.458495787466945 0.999713215040601 1 GO:0046943 carboxylic acid transmembrane transporter activity 15/3030 188/18639 0.0797872340425532 0.490809985253845 0.999735157473872 1 GO:0004497 monooxygenase activity 6/3030 106/18639 0.0566037735849057 0.348197272557444 0.999758006537555 1 GO:0005342 organic acid transmembrane transporter activity 15/3030 189/18639 0.0793650793650794 0.488213107024988 0.999761541879906 1 GO:0008509 monoatomic anion transmembrane transporter activity 10/3030 149/18639 0.0671140939597315 0.412851352249319 0.999859755650165 1 GO:0005262 calcium channel activity 8/3030 131/18639 0.0610687022900763 0.375663215176479 0.99987646652102 1 GO:0099106 ion channel regulator activity 11/3030 160/18639 0.06875 0.422914603960396 0.999885698306206 1 GO:0015079 potassium ion transmembrane transporter activity 10/3030 160/18639 0.0625 0.384467821782178 0.99996309455547 1 GO:0005249 voltage-gated potassium channel activity 4/3030 98/18639 0.0408163265306122 0.251081026469994 0.999964289293503 1 GO:0015108 chloride transmembrane transporter activity 6/3030 121/18639 0.0495867768595041 0.30503232141396 0.999968440580455 1 GO:0005267 potassium channel activity 6/3030 124/18639 0.0483870967741935 0.297652507186203 0.999979197197845 1 GO:0015103 inorganic anion transmembrane transporter activity 10/3030 165/18639 0.0606060606060606 0.372817281728173 0.999980164836917 1 GO:0015085 calcium ion transmembrane transporter activity 8/3030 147/18639 0.054421768707483 0.334774701959992 0.999984401472134 1 GO:0015294 solute:monoatomic cation symporter activity 5/3030 116/18639 0.0431034482758621 0.265150221918744 0.999986409778411 1 GO:0008083 growth factor activity 9/3030 162/18639 0.0555555555555556 0.341749174917492 0.999991765722969 1 GO:0005254 chloride channel activity 2/3030 83/18639 0.0240963855421687 0.148228557795539 0.999993315565285 1 GO:0004252 serine-type endopeptidase activity 10/3030 176/18639 0.0568181818181818 0.349516201620162 0.999995079028373 1 GO:0015293 symporter activity 7/3030 146/18639 0.0479452054794521 0.294934219449342 0.999995654271936 1 GO:0008236 serine-type peptidase activity 11/3030 194/18639 0.0567010309278351 0.348795549658059 0.999998243814292 1 GO:0001664 G protein-coupled receptor binding 22/3030 297/18639 0.0740740740740741 0.455665566556656 0.999998367726247 1 GO:0015081 sodium ion transmembrane transporter activity 8/3030 164/18639 0.0487804878048781 0.300072446269017 0.999998415931633 1 GO:0017171 serine hydrolase activity 11/3030 198/18639 0.0555555555555556 0.341749174917492 0.999998949335845 1 GO:0005244 voltage-gated monoatomic ion channel activity 8/3030 173/18639 0.046242774566474 0.284461740971785 0.999999542526326 1 GO:0022832 voltage-gated channel activity 8/3030 175/18639 0.0457142857142857 0.281210749646393 0.999999653779563 1 GO:0022843 voltage-gated monoatomic cation channel activity 5/3030 143/18639 0.034965034965035 0.215086893304715 0.999999753675577 1 GO:0008528 G protein-coupled peptide receptor activity 2/3030 122/18639 0.0163934426229508 0.100844018828112 0.999999990831687 1 GO:0046873 metal ion transmembrane transporter activity 33/3030 450/18639 0.0733333333333333 0.451108910891089 0.999999996009347 1 GO:0001653 peptide receptor activity 2/3030 128/18639 0.015625 0.0961169554455445 0.99999999671305 1 GO:0003823 antigen binding 5/3030 174/18639 0.028735632183908 0.176766814612496 0.999999997929896 1 GO:0005179 hormone activity 2/3030 132/18639 0.0151515151515152 0.0932043204320432 0.999999998343434 1 GO:0099094 ligand-gated monoatomic cation channel activity 2/3030 136/18639 0.0147058823529412 0.0904630168899243 0.999999999165971 1 GO:0022834 ligand-gated channel activity 4/3030 188/18639 0.0212765957446809 0.130882662734359 0.999999999975574 1 GO:0005261 monoatomic cation channel activity 17/3030 341/18639 0.0498533724340176 0.306672280131239 0.999999999976447 1 GO:0045182 translation regulator activity 17/3030 356/18639 0.047752808988764 0.293750695294249 0.999999999996847 1 GO:0015276 ligand-gated monoatomic ion channel activity 3/3030 186/18639 0.0161290322580645 0.0992175023954008 0.999999999997267 1 GO:0005125 cytokine activity 6/3030 234/18639 0.0256410256410256 0.157730388423458 0.999999999998695 1 GO:0005216 monoatomic ion channel activity 24/3030 448/18639 0.0535714285714286 0.329543847241867 0.999999999999778 1 GO:0022836 gated channel activity 11/3030 318/18639 0.0345911949685535 0.212787222118438 0.999999999999949 1 GO:0030371 translation repressor activity 6/3030 329/18639 0.0182370820668693 0.112185139486593 1 1