ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 78/726 175/18639 0.445714285714286 11.4430696576151 6.29269660657209e-63 5.73264660858718e-60 GO:0045296 cadherin binding 52/726 334/18639 0.155688622754491 3.99708021972584 9.37952233558645e-18 4.27237242385963e-15 GO:0005201 extracellular matrix structural constituent 33/726 168/18639 0.196428571428571 5.04301948051948 1.12560683790577e-14 3.41809276444051e-12 GO:0019843 rRNA binding 20/726 65/18639 0.307692307692308 7.89955499046408 2.71776463980821e-13 6.18970896716319e-11 GO:0005539 glycosaminoglycan binding 34/726 242/18639 0.140495867768595 3.60702820845571 8.75937548210266e-11 1.5959582128391e-08 GO:0008135 translation factor activity, RNA binding 19/726 83/18639 0.228915662650602 5.87707856218261 3.22611112544548e-10 4.89831205880139e-08 GO:0180051 translation factor activity 19/726 84/18639 0.226190476190476 5.80711334120425 4.01926163340136e-10 5.2307819257552e-08 GO:0005178 integrin binding 24/726 161/18639 0.149068322981366 3.82711359786459 1.61449853885941e-08 1.83851021112615e-06 GO:1990948 ubiquitin ligase inhibitor activity 7/726 11/18639 0.636363636363636 16.3377160030053 3.80519969227076e-08 3.85170768850963e-06 GO:0004857 enzyme inhibitor activity 41/726 416/18639 0.0985576923076923 2.53032620788303 5.14325094567451e-08 4.28479980806453e-06 GO:0003743 translation initiation factor activity 13/726 51/18639 0.254901960784314 6.54423918327662 5.17374290765201e-08 4.28479980806453e-06 GO:0008201 heparin binding 24/726 172/18639 0.13953488372093 3.58235633288487 5.94257778851894e-08 4.5114069711173e-06 GO:0019838 growth factor binding 21/726 136/18639 0.154411764705882 3.96429873602334 6.8081223914312e-08 4.77092269122602e-06 GO:1901681 sulfur compound binding 31/726 275/18639 0.112727272727273 2.89410969196093 1.16747311945693e-07 7.59691437018044e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/726 15/18639 0.466666666666667 11.9809917355372 6.4701405397145e-07 3.92953202111994e-05 GO:0031625 ubiquitin protein ligase binding 31/726 302/18639 0.102649006622517 2.63536478572601 9.26093807656507e-07 5.27294661734424e-05 GO:0002020 protease binding 19/726 136/18639 0.139705882352941 3.58674647544968 1.37912465960308e-06 7.390485675873e-05 GO:0048027 mRNA 5'-UTR binding 8/726 24/18639 0.333333333333333 8.55785123966942 2.15312346365506e-06 0.000108971970854987 GO:0061134 peptidase regulator activity 25/726 226/18639 0.110619469026549 2.83999488042127 2.73944923240883e-06 0.000131349381617076 GO:0044389 ubiquitin-like protein ligase binding 31/726 322/18639 0.0962732919254658 2.47167753195421 3.58478851004877e-06 0.000163287116632721 GO:0050840 extracellular matrix binding 12/726 67/18639 0.17910447761194 4.59824842728506 9.3309141687422e-06 0.000404783943224959 GO:0005518 collagen binding 12/726 72/18639 0.166666666666667 4.27892561983471 2.00061600892296e-05 0.000828436901876737 GO:0030020 extracellular matrix structural constituent conferring tensile strength 9/726 44/18639 0.204545454545455 5.25140871525169 4.09012056759537e-05 0.00161269634723666 GO:0003746 translation elongation factor activity 6/726 18/18639 0.333333333333333 8.55785123966942 4.24859630446542e-05 0.00161269634723666 GO:0055106 ubiquitin-protein transferase regulator activity 8/726 36/18639 0.222222222222222 5.70523415977961 5.85337613849171e-05 0.00213297026486638 GO:0016504 peptidase activator activity 10/726 57/18639 0.175438596491228 4.50413223140496 6.21199683370825e-05 0.00214755030097734 GO:0043021 ribonucleoprotein complex binding 19/726 177/18639 0.107344632768362 2.75591819582575 6.36485819170012e-05 0.00214755030097734 GO:0051082 unfolded protein binding 15/726 121/18639 0.12396694214876 3.18267194863739 7.28033522464029e-05 0.00236870906773118 GO:0001968 fibronectin binding 7/726 30/18639 0.233333333333333 5.9904958677686 0.000122789301065919 0.0038572776990018 GO:0003779 actin binding 34/726 443/18639 0.0767494356659142 1.97043075947242 0.000139349182420897 0.00423157017284792 GO:0140311 protein sequestering activity 7/726 33/18639 0.212121212121212 5.44590533433509 0.000232759945843725 0.00668358316453442 GO:0046332 SMAD binding 11/726 79/18639 0.139240506329114 3.57479861910242 0.000234769112255874 0.00668358316453442 GO:0140313 molecular sequestering activity 9/726 55/18639 0.163636363636364 4.20112697220135 0.000250333612771029 0.00691072488589113 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/726 45/18639 0.177777777777778 4.56418732782369 0.00030604918836172 0.00809747786762685 GO:0042277 peptide binding 22/726 249/18639 0.0883534136546185 2.26834611171961 0.000311099588767222 0.00809747786762685 GO:0005522 profilin binding 4/726 10/18639 0.4 10.2694214876033 0.000397233756064238 0.00993860875317401 GO:0005112 Notch binding 6/726 26/18639 0.230769230769231 5.92466624284806 0.000403653703476881 0.00993860875317401 GO:0043022 ribosome binding 13/726 112/18639 0.116071428571429 2.9799660566706 0.000416759111206959 0.00999125132393525 GO:0001221 transcription coregulator binding 13/726 115/18639 0.11304347826087 2.90222781171398 0.000538768486303255 0.0125287025510434 GO:0051015 actin filament binding 19/726 209/18639 0.0909090909090909 2.33395942900075 0.00055010768610509 0.0125287025510434 GO:0048407 platelet-derived growth factor binding 4/726 11/18639 0.363636363636364 9.33583771600301 0.000605028656367257 0.0134434416085505 GO:0005520 insulin-like growth factor binding 5/726 19/18639 0.263157894736842 6.75619834710744 0.000652025160157635 0.0141427362119906 GO:0061135 endopeptidase regulator activity 17/726 184/18639 0.0923913043478261 2.37201311534315 0.000880862920393929 0.0186620028018342 GO:0016860 intramolecular oxidoreductase activity 8/726 53/18639 0.150943396226415 3.87525339154842 0.000957143738434988 0.0198172260389608 GO:0031994 insulin-like growth factor I binding 4/726 13/18639 0.307692307692308 7.89955499046408 0.00123167044864165 0.0245181216042994 GO:1990841 promoter-specific chromatin binding 9/726 68/18639 0.132352941176471 3.39797034516286 0.00123801711723136 0.0245181216042994 GO:0140297 DNA-binding transcription factor binding 33/726 488/18639 0.0676229508196721 1.73612146050671 0.00156977578883386 0.0302111592791126 GO:0004866 endopeptidase inhibitor activity 15/726 161/18639 0.093167701863354 2.39194599866537 0.00159180641646257 0.0302111592791126 GO:0015035 protein-disulfide reductase activity 6/726 34/18639 0.176470588235294 4.53062712688381 0.00180940406980526 0.0336401450529101 GO:0045309 protein phosphorylated amino acid binding 8/726 59/18639 0.135593220338983 3.48115982630621 0.00195183841070924 0.0355624958431223 GO:0001784 phosphotyrosine residue binding 7/726 47/18639 0.148936170212766 3.8237207666608 0.00213759673685367 0.0379809555355938 GO:0031386 protein tag activity 4/726 15/18639 0.266666666666667 6.84628099173554 0.00220964944389295 0.0379809555355938 GO:0141047 molecular tag activity 4/726 15/18639 0.266666666666667 6.84628099173554 0.00220964944389295 0.0379809555355938 GO:0019887 protein kinase regulator activity 20/726 255/18639 0.0784313725490196 2.0136120563928 0.0024379817567182 0.0411296551920423 GO:0030414 peptidase inhibitor activity 15/726 169/18639 0.0887573964497041 2.27871778571079 0.00256084819218522 0.0424169582378315 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 25/726 349/18639 0.0716332378223496 1.83907977929859 0.00262891887247192 0.0427668766575342 GO:0043394 proteoglycan binding 6/726 37/18639 0.162162162162162 4.1632789814608 0.00283332076394595 0.0452834248413116 GO:0005080 protein kinase C binding 7/726 52/18639 0.134615384615385 3.45605530832804 0.00384603183921232 0.0604092242331453 GO:0051019 mitogen-activated protein kinase binding 5/726 28/18639 0.178571428571429 4.58456316410862 0.00412456434551106 0.0636860698095013 GO:0015036 disulfide oxidoreductase activity 6/726 40/18639 0.15 3.85103305785124 0.00423876814451332 0.0641305431794584 GO:0005200 structural constituent of cytoskeleton 11/726 112/18639 0.0982142857142857 2.52150974025974 0.00429604338414517 0.0641305431794584 GO:0019207 kinase regulator activity 21/726 287/18639 0.0731707317073171 1.87855271114695 0.00436453751605535 0.0641305431794584 GO:0008083 growth factor activity 14/726 162/18639 0.0864197530864197 2.21870217324763 0.00445239626787007 0.0642537286875149 GO:0098641 cadherin binding involved in cell-cell adhesion 4/726 18/18639 0.222222222222222 5.70523415977961 0.00451398313501751 0.0642537286875149 GO:0003785 actin monomer binding 5/726 29/18639 0.172413793103448 4.42647477913936 0.00482677445474779 0.0676491004350036 GO:0004860 protein kinase inhibitor activity 9/726 84/18639 0.107142857142857 2.75073789846517 0.00534038448300426 0.0737134888487406 GO:0043395 heparan sulfate proteoglycan binding 4/726 19/18639 0.210526315789474 5.40495867768595 0.00554383859498014 0.0753796561198046 GO:0030957 Tat protein binding 3/726 10/18639 0.3 7.70206611570248 0.00575132946525503 0.0770508991595196 GO:0043024 ribosomal small subunit binding 4/726 20/18639 0.2 5.13471074380165 0.00671937131324615 0.0887151777734383 GO:0044325 transmembrane transporter binding 12/726 136/18639 0.0882352941176471 2.26531356344191 0.00691525621360224 0.0899971201513092 GO:0051059 NF-kappaB binding 5/726 32/18639 0.15625 4.01149276859504 0.00743673208968295 0.0954206047000165 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/726 11/18639 0.272727272727273 7.00187828700225 0.00768119226858795 0.0971884188428281 GO:0001846 opsonin binding 4/726 21/18639 0.19047619047619 4.89020070838253 0.00804872235938226 0.100443644786264 GO:0019210 kinase inhibitor activity 9/726 90/18639 0.1 2.56735537190083 0.00834821699979104 0.102773320092022 GO:0044183 protein folding chaperone 8/726 75/18639 0.106666666666667 2.73851239669421 0.00863863992138112 0.104930679578376 GO:0140517 protein-RNA adaptor activity 4/726 22/18639 0.181818181818182 4.6679188580015 0.00953948814385215 0.114348338145386 GO:0004859 phospholipase inhibitor activity 3/726 12/18639 0.25 6.41838842975207 0.00994836551096166 0.116191807442129 GO:0097371 MDM2/MDM4 family protein binding 3/726 12/18639 0.25 6.41838842975207 0.00994836551096166 0.116191807442129 GO:0016853 isomerase activity 14/726 180/18639 0.0777777777777778 1.99683195592287 0.0109527633467545 0.126303384922701 GO:0017134 fibroblast growth factor binding 4/726 23/18639 0.173913043478261 4.46496586417535 0.0111986948725295 0.12752513786093 GO:0004867 serine-type endopeptidase inhibitor activity 9/726 95/18639 0.0947368421052632 2.43223140495868 0.0117161024323824 0.131769991554326 GO:0005540 hyaluronic acid binding 4/726 24/18639 0.166666666666667 4.27892561983471 0.0130327796374305 0.143046533128906 GO:0050431 transforming growth factor beta binding 4/726 24/18639 0.166666666666667 4.27892561983471 0.0130327796374305 0.143046533128906 GO:0051087 protein-folding chaperone binding 11/726 134/18639 0.082089552238806 2.10753052917232 0.0157102556698781 0.170381463276892 GO:0019208 phosphatase regulator activity 10/726 117/18639 0.0854700854700855 2.19432083068447 0.0160375490769523 0.171884790695336 GO:0050681 nuclear androgen receptor binding 4/726 26/18639 0.153846153846154 3.94977749523204 0.0172483136154469 0.182711787252001 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/726 54/18639 0.111111111111111 2.85261707988981 0.0180655821332012 0.188856645614903 GO:0016209 antioxidant activity 8/726 86/18639 0.0930232558139535 2.38823755525658 0.0187796920151187 0.188856645614903 GO:0004129 cytochrome-c oxidase activity 3/726 15/18639 0.2 5.13471074380165 0.0188649338649355 0.188856645614903 GO:0005041 low-density lipoprotein particle receptor activity 3/726 15/18639 0.2 5.13471074380165 0.0188649338649355 0.188856645614903 GO:0120283 protein serine/threonine kinase binding 3/726 15/18639 0.2 5.13471074380165 0.0188649338649355 0.188856645614903 GO:0008266 poly(U) RNA binding 4/726 27/18639 0.148148148148148 3.80348943985308 0.0196396007637994 0.1923836160841 GO:0023026 MHC class II protein complex binding 4/726 27/18639 0.148148148148148 3.80348943985308 0.0196396007637994 0.1923836160841 GO:0004713 protein tyrosine kinase activity 11/726 140/18639 0.0785714285714286 2.01720779220779 0.0210779859385835 0.204132950536594 GO:0019212 phosphatase inhibitor activity 6/726 56/18639 0.107142857142857 2.75073789846517 0.0212871902315878 0.204132950536594 GO:0051020 GTPase binding 20/726 315/18639 0.0634920634920635 1.63006690279418 0.0225237698579722 0.208078253112332 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/726 16/18639 0.1875 4.81379132231405 0.0225592519460849 0.208078253112332 GO:0055102 lipase inhibitor activity 3/726 16/18639 0.1875 4.81379132231405 0.0225592519460849 0.208078253112332 GO:0003727 single-stranded RNA binding 8/726 89/18639 0.0898876404494382 2.30773516575355 0.0226122360681898 0.208078253112332 GO:0043236 laminin binding 4/726 29/18639 0.137931034482759 3.54117982331148 0.0250092266807835 0.225578272338552 GO:0099604 ligand-gated calcium channel activity 4/726 29/18639 0.137931034482759 3.54117982331148 0.0250092266807835 0.225578272338552 GO:0016018 cyclosporin A binding 3/726 17/18639 0.176470588235294 4.53062712688381 0.0266174161916844 0.235464478927912 GO:0003725 double-stranded RNA binding 7/726 75/18639 0.0933333333333333 2.39619834710744 0.026622218803046 0.235464478927912 GO:0008187 poly-pyrimidine tract binding 4/726 30/18639 0.133333333333333 3.42314049586777 0.0279937569616029 0.245214544154041 GO:0051219 phosphoprotein binding 8/726 93/18639 0.0860215053763441 2.20847773926953 0.0285367538766809 0.247590312206251 GO:0015026 coreceptor activity 6/726 61/18639 0.0983606557377049 2.52526757891885 0.0309810588727889 0.264258987416347 GO:0030228 lipoprotein particle receptor activity 3/726 18/18639 0.166666666666667 4.27892561983471 0.0310381028030178 0.264258987416347 GO:0033218 amide binding 16/726 247/18639 0.0647773279352227 1.66306420851875 0.0328368768287248 0.27698513695341 GO:0003924 GTPase activity 20/726 331/18639 0.0604229607250755 1.55127212803675 0.0353958639216745 0.292848073391316 GO:0035401 histone H3Y41 kinase activity 9/726 115/18639 0.0782608695652174 2.00923463887891 0.0356818179433986 0.292848073391316 GO:0140801 histone H2AXY142 kinase activity 9/726 115/18639 0.0782608695652174 2.00923463887891 0.0356818179433986 0.292848073391316 GO:0000049 tRNA binding 7/726 80/18639 0.0875 2.24643595041322 0.0361685486210942 0.294192391016222 GO:0038024 cargo receptor activity 6/726 65/18639 0.0923076923076923 2.36986649713922 0.040531582862325 0.320663489675587 GO:0042288 MHC class I protein binding 3/726 20/18639 0.15 3.85103305785124 0.040953378405927 0.320663489675587 GO:0001222 transcription corepressor binding 5/726 49/18639 0.102040816326531 2.61975037949064 0.0411670186793205 0.320663489675587 GO:0019001 guanyl nucleotide binding 23/726 400/18639 0.0575 1.47622933884298 0.0411829070165134 0.320663489675587 GO:0032561 guanyl ribonucleotide binding 23/726 400/18639 0.0575 1.47622933884298 0.0411829070165134 0.320663489675587 GO:0008238 exopeptidase activity 8/726 102/18639 0.0784313725490196 2.0136120563928 0.045587247727383 0.349624391219282 GO:0036122 BMP binding 3/726 21/18639 0.142857142857143 3.66765053128689 0.0464374877470177 0.349624391219282 GO:0070182 DNA polymerase binding 3/726 21/18639 0.142857142857143 3.66765053128689 0.0464374877470177 0.349624391219282 GO:0072542 protein phosphatase activator activity 3/726 21/18639 0.142857142857143 3.66765053128689 0.0464374877470177 0.349624391219282 GO:0005048 signal sequence binding 5/726 51/18639 0.0980392156862745 2.51701507049101 0.0476445729929377 0.355772180299724 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 6/726 68/18639 0.0882352941176471 2.26531356344191 0.0487935959647729 0.357990558463399 GO:0003712 transcription coregulator activity 27/726 495/18639 0.0545454545454545 1.40037565740045 0.0498593294994144 0.357990558463399 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/726 36/18639 0.111111111111111 2.85261707988981 0.050201053432646 0.357990558463399 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/726 36/18639 0.111111111111111 2.85261707988981 0.050201053432646 0.357990558463399 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/726 36/18639 0.111111111111111 2.85261707988981 0.050201053432646 0.357990558463399 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/726 22/18639 0.136363636363636 3.50093914350113 0.0522634876843596 0.357990558463399 GO:0023023 MHC protein complex binding 4/726 37/18639 0.108108108108108 2.77551932097387 0.0546217139924586 0.357990558463399 GO:0004864 protein phosphatase inhibitor activity 5/726 53/18639 0.0943396226415094 2.42203336971776 0.054691392855181 0.357990558463399 GO:0005246 calcium channel regulator activity 5/726 53/18639 0.0943396226415094 2.42203336971776 0.054691392855181 0.357990558463399 GO:0001094 TFIID-class transcription factor complex binding 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0005131 growth hormone receptor binding 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0005528 FK506 binding 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0008239 dipeptidyl-peptidase activity 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0032395 MHC class II receptor activity 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0070513 death domain binding 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0098505 G-rich strand telomeric DNA binding 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0140135 mechanosensitive monoatomic cation channel activity 2/726 10/18639 0.2 5.13471074380165 0.0554079788620629 0.357990558463399 GO:0019888 protein phosphatase regulator activity 8/726 107/18639 0.0747663551401869 1.91951803506604 0.0574528737055705 0.368588506660386 GO:0042826 histone deacetylase binding 9/726 127/18639 0.0708661417322835 1.81938569662263 0.060205315541925 0.380624630002367 GO:0005516 calmodulin binding 13/726 207/18639 0.0628019323671498 1.61234878428554 0.061935545881312 0.380624630002367 GO:0019209 kinase activator activity 10/726 148/18639 0.0675675675675676 1.73469957560867 0.0640149815819859 0.380624630002367 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/726 39/18639 0.102564102564103 2.63318499682136 0.0640711921945408 0.380624630002367 GO:0016247 channel regulator activity 11/726 168/18639 0.0654761904761905 1.68100649350649 0.0645228613559238 0.380624630002367 GO:0005525 GTP binding 21/726 378/18639 0.0555555555555556 1.4263085399449 0.0659665215311024 0.380624630002367 GO:0005114 type II transforming growth factor beta receptor binding 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0008432 JUN kinase binding 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0032050 clathrin heavy chain binding 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0034713 type I transforming growth factor beta receptor binding 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0043522 leucine zipper domain binding 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0050786 RAGE receptor binding 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0050998 nitric-oxide synthase binding 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0097493 structural molecule activity conferring elasticity 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/726 11/18639 0.181818181818182 4.6679188580015 0.0660139314383907 0.380624630002367 GO:0141108 transporter regulator activity 11/726 170/18639 0.0647058823529412 1.66122994652406 0.0689596472719738 0.386173863718578 GO:0004177 aminopeptidase activity 4/726 40/18639 0.1 2.56735537190083 0.0690958724326326 0.386173863718578 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/726 40/18639 0.1 2.56735537190083 0.0690958724326326 0.386173863718578 GO:0071949 FAD binding 4/726 40/18639 0.1 2.56735537190083 0.0690958724326326 0.386173863718578 GO:0140662 ATP-dependent protein folding chaperone 4/726 40/18639 0.1 2.56735537190083 0.0690958724326326 0.386173863718578 GO:0031072 heat shock protein binding 9/726 131/18639 0.0687022900763359 1.7638319348937 0.0703092600385953 0.390559365214392 GO:0001848 complement binding 3/726 25/18639 0.12 3.08082644628099 0.0717066409333839 0.391166167007861 GO:0008139 nuclear localization sequence binding 3/726 25/18639 0.12 3.08082644628099 0.0717066409333839 0.391166167007861 GO:0019211 phosphatase activator activity 3/726 25/18639 0.12 3.08082644628099 0.0717066409333839 0.391166167007861 GO:0005126 cytokine receptor binding 16/726 275/18639 0.0581818181818182 1.49373403456048 0.0724586383402414 0.392915592428333 GO:0042169 SH2 domain binding 4/726 41/18639 0.0975609756097561 2.50473694819593 0.0743170894185132 0.396916281579187 GO:0098631 cell adhesion mediator activity 6/726 76/18639 0.0789473684210526 2.02685950413223 0.0755654741484103 0.396916281579187 GO:0005049 nuclear export signal receptor activity 2/726 12/18639 0.166666666666667 4.27892561983471 0.0772270446238764 0.396916281579187 GO:0005527 macrolide binding 2/726 12/18639 0.166666666666667 4.27892561983471 0.0772270446238764 0.396916281579187 GO:0043047 single-stranded telomeric DNA binding 2/726 12/18639 0.166666666666667 4.27892561983471 0.0772270446238764 0.396916281579187 GO:0005160 transforming growth factor beta receptor binding 3/726 26/18639 0.115384615384615 2.96233312142403 0.0788099010183322 0.396916281579187 GO:0008143 poly(A) binding 3/726 26/18639 0.115384615384615 2.96233312142403 0.0788099010183322 0.396916281579187 GO:0070006 metalloaminopeptidase activity 3/726 26/18639 0.115384615384615 2.96233312142403 0.0788099010183322 0.396916281579187 GO:0070412 R-SMAD binding 3/726 26/18639 0.115384615384615 2.96233312142403 0.0788099010183322 0.396916281579187 GO:0001786 phosphatidylserine binding 5/726 59/18639 0.0847457627118644 2.17572489144138 0.0792395343866445 0.396916281579187 GO:0008307 structural constituent of muscle 4/726 42/18639 0.0952380952380952 2.44510035419126 0.0797318106794634 0.396916281579187 GO:0016859 cis-trans isomerase activity 4/726 42/18639 0.0952380952380952 2.44510035419126 0.0797318106794634 0.396916281579187 GO:0035198 miRNA binding 4/726 42/18639 0.0952380952380952 2.44510035419126 0.0797318106794634 0.396916281579187 GO:0042056 chemoattractant activity 4/726 42/18639 0.0952380952380952 2.44510035419126 0.0797318106794634 0.396916281579187 GO:0051879 Hsp90 protein binding 4/726 42/18639 0.0952380952380952 2.44510035419126 0.0797318106794634 0.396916281579187 GO:0030246 carbohydrate binding 16/726 280/18639 0.0571428571428571 1.46706021251476 0.0819214889192354 0.405600415246867 GO:0008200 ion channel inhibitor activity 4/726 43/18639 0.0930232558139535 2.38823755525658 0.0853366600784681 0.420225390980997 GO:0005044 scavenger receptor activity 3/726 27/18639 0.111111111111111 2.85261707988981 0.0862061885501488 0.422210900567488 GO:0016835 carbon-oxygen lyase activity 6/726 79/18639 0.0759493670886076 1.94989015587405 0.0873859132764267 0.422210900567488 GO:0031267 small GTPase binding 16/726 283/18639 0.0565371024734982 1.45150833747043 0.087967481975962 0.422210900567488 GO:0019855 calcium channel inhibitor activity 2/726 13/18639 0.153846153846154 3.94977749523204 0.0889840756410072 0.422210900567488 GO:0035325 Toll-like receptor binding 2/726 13/18639 0.153846153846154 3.94977749523204 0.0889840756410072 0.422210900567488 GO:0045159 myosin II binding 2/726 13/18639 0.153846153846154 3.94977749523204 0.0889840756410072 0.422210900567488 GO:0140666 annealing activity 2/726 13/18639 0.153846153846154 3.94977749523204 0.0889840756410072 0.422210900567488 GO:0001046 core promoter sequence-specific DNA binding 4/726 44/18639 0.0909090909090909 2.33395942900075 0.0911279409463776 0.425468013846048 GO:0001223 transcription coactivator binding 4/726 44/18639 0.0909090909090909 2.33395942900075 0.0911279409463776 0.425468013846048 GO:0016248 channel inhibitor activity 4/726 44/18639 0.0909090909090909 2.33395942900075 0.0911279409463776 0.425468013846048 GO:0048306 calcium-dependent protein binding 6/726 80/18639 0.075 1.92551652892562 0.091538672572805 0.425468013846048 GO:0030295 protein kinase activator activity 9/726 139/18639 0.0647482014388489 1.66231642784946 0.0935085942778541 0.429790015992202 GO:0046875 ephrin receptor binding 3/726 28/18639 0.107142857142857 2.75073789846517 0.093883878356145 0.429790015992202 GO:0097718 disordered domain specific binding 3/726 28/18639 0.107142857142857 2.75073789846517 0.093883878356145 0.429790015992202 GO:0099106 ion channel regulator activity 10/726 160/18639 0.0625 1.60459710743802 0.0956771720991941 0.434181851775308 GO:0001618 virus receptor activity 6/726 81/18639 0.0740740740740741 1.90174471992654 0.0957964349142009 0.434181851775308 GO:0042605 peptide antigen binding 4/726 45/18639 0.0888888888888889 2.28209366391185 0.0971016589926587 0.435761632228138 GO:0141110 transporter inhibitor activity 4/726 45/18639 0.0888888888888889 2.28209366391185 0.0971016589926587 0.435761632228138 GO:0140272 exogenous protein binding 6/726 82/18639 0.0731707317073171 1.87855271114695 0.10015825584567 0.446661972401953 GO:0004065 arylsulfatase activity 2/726 14/18639 0.142857142857143 3.66765053128689 0.101225775417721 0.446661972401953 GO:0098847 sequence-specific single stranded DNA binding 2/726 14/18639 0.142857142857143 3.66765053128689 0.101225775417721 0.446661972401953 GO:0030695 GTPase regulator activity 25/726 489/18639 0.0511247443762781 1.31255387111494 0.101491798339412 0.446661972401953 GO:0060589 nucleoside-triphosphatase regulator activity 25/726 490/18639 0.0510204081632653 1.30987518974532 0.103219596136869 0.447923711480332 GO:0004180 carboxypeptidase activity 4/726 46/18639 0.0869565217391304 2.23248293208768 0.103253544907651 0.447923711480332 GO:0030276 clathrin binding 4/726 46/18639 0.0869565217391304 2.23248293208768 0.103253544907651 0.447923711480332 GO:0001540 amyloid-beta binding 6/726 83/18639 0.072289156626506 1.8559195459524 0.104623086631181 0.451713895360218 GO:0008237 metallopeptidase activity 11/726 184/18639 0.0597826086956522 1.53483201581028 0.105426219242047 0.453034366648609 GO:0140104 molecular carrier activity 14/726 249/18639 0.0562248995983936 1.4434929801852 0.108747342464275 0.465111873168801 GO:0019955 cytokine binding 9/726 144/18639 0.0625 1.60459710743802 0.110030016096917 0.466241692115516 GO:0016769 transferase activity, transferring nitrogenous groups 3/726 30/18639 0.1 2.56735537190083 0.110035086503662 0.466241692115516 GO:0008235 metalloexopeptidase activity 5/726 66/18639 0.0757575757575758 1.94496619083396 0.114116355039743 0.481296293709288 GO:0005085 guanyl-nucleotide exchange factor activity 13/726 230/18639 0.0565217391304348 1.45111390585699 0.115524336439667 0.484989264960998 GO:0140597 protein carrier chaperone 11/726 188/18639 0.0585106382978723 1.50217601547389 0.11758587790786 0.491209754817547 GO:0070325 lipoprotein particle receptor binding 3/726 31/18639 0.0967741935483871 2.48453745667822 0.118483712860662 0.491209754817547 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/726 86/18639 0.0697674418604651 1.79117816644244 0.118623650998749 0.491209754817547 GO:0016763 pentosyltransferase activity 4/726 49/18639 0.0816326530612245 2.09580030359251 0.122731854835681 0.495070488139408 GO:0004708 MAP kinase kinase activity 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0005024 transforming growth factor beta receptor activity 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0005521 lamin binding 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0008142 oxysterol binding 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0022841 potassium ion leak channel activity 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0030275 LRR domain binding 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0043023 ribosomal large subunit binding 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0070411 I-SMAD binding 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/726 16/18639 0.125 3.20919421487603 0.126944877285587 0.495070488139408 GO:0031369 translation initiation factor binding 3/726 32/18639 0.09375 2.40689566115702 0.127164099039101 0.495070488139408 GO:0070717 poly-purine tract binding 3/726 32/18639 0.09375 2.40689566115702 0.127164099039101 0.495070488139408 GO:0140142 nucleocytoplasmic carrier activity 3/726 32/18639 0.09375 2.40689566115702 0.127164099039101 0.495070488139408 GO:0046982 protein heterodimerization activity 19/726 369/18639 0.0514905149051491 1.32194450043674 0.132443964259589 0.513431708257384 GO:0140416 transcription regulator inhibitor activity 3/726 33/18639 0.0909090909090909 2.33395942900075 0.136063403683029 0.525227799810336 GO:0008484 sulfuric ester hydrolase activity 2/726 17/18639 0.117647058823529 3.02041808458921 0.140321872098107 0.526062656301957 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/726 17/18639 0.117647058823529 3.02041808458921 0.140321872098107 0.526062656301957 GO:0015278 intracellularly gated calcium channel activity 2/726 17/18639 0.117647058823529 3.02041808458921 0.140321872098107 0.526062656301957 GO:0032977 membrane insertase activity 2/726 17/18639 0.117647058823529 3.02041808458921 0.140321872098107 0.526062656301957 GO:0045236 CXCR chemokine receptor binding 2/726 17/18639 0.117647058823529 3.02041808458921 0.140321872098107 0.526062656301957 GO:0046965 nuclear retinoid X receptor binding 2/726 17/18639 0.117647058823529 3.02041808458921 0.140321872098107 0.526062656301957 GO:0070492 oligosaccharide binding 2/726 17/18639 0.117647058823529 3.02041808458921 0.140321872098107 0.526062656301957 GO:1902936 phosphatidylinositol bisphosphate binding 7/726 111/18639 0.0630630630630631 1.61905293723476 0.142363669890391 0.531529931435024 GO:0072341 modified amino acid binding 6/726 91/18639 0.0659340659340659 1.69276178367087 0.143892327504591 0.533260952363082 GO:0003730 mRNA 3'-UTR binding 14/726 262/18639 0.0534351145038168 1.3718692826951 0.145069479074192 0.533260952363082 GO:0030332 cyclin binding 3/726 34/18639 0.0882352941176471 2.26531356344191 0.145168733464374 0.533260952363082 GO:0051427 hormone receptor binding 3/726 34/18639 0.0882352941176471 2.26531356344191 0.145168733464374 0.533260952363082 GO:0005544 calcium-dependent phospholipid binding 4/726 53/18639 0.0754716981132075 1.93762669577421 0.150899109243716 0.5498763540841 GO:0140296 general transcription initiation factor binding 4/726 53/18639 0.0754716981132075 1.93762669577421 0.150899109243716 0.5498763540841 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/726 18/18639 0.111111111111111 2.85261707988981 0.153982343259993 0.554458160908513 GO:0034185 apolipoprotein binding 2/726 18/18639 0.111111111111111 2.85261707988981 0.153982343259993 0.554458160908513 GO:0070064 proline-rich region binding 2/726 18/18639 0.111111111111111 2.85261707988981 0.153982343259993 0.554458160908513 GO:0031491 nucleosome binding 5/726 74/18639 0.0675675675675676 1.73469957560867 0.161367407027039 0.578762629140287 GO:0098632 cell-cell adhesion mediator activity 4/726 55/18639 0.0727272727272727 1.8671675432006 0.16582523397018 0.581529742377557 GO:0016922 nuclear receptor binding 8/726 137/18639 0.0583941605839416 1.49918561862822 0.166087976902587 0.581529742377557 GO:0003756 protein disulfide isomerase activity 2/726 19/18639 0.105263157894737 2.70247933884298 0.167883998073872 0.581529742377557 GO:0008381 mechanosensitive monoatomic ion channel activity 2/726 19/18639 0.105263157894737 2.70247933884298 0.167883998073872 0.581529742377557 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/726 19/18639 0.105263157894737 2.70247933884298 0.167883998073872 0.581529742377557 GO:0022840 leak channel activity 2/726 19/18639 0.105263157894737 2.70247933884298 0.167883998073872 0.581529742377557 GO:0022842 narrow pore channel activity 2/726 19/18639 0.105263157894737 2.70247933884298 0.167883998073872 0.581529742377557 GO:0034987 immunoglobulin receptor binding 2/726 19/18639 0.105263157894737 2.70247933884298 0.167883998073872 0.581529742377557 GO:0140036 ubiquitin-modified protein reader activity 2/726 19/18639 0.105263157894737 2.70247933884298 0.167883998073872 0.581529742377557 GO:0003714 transcription corepressor activity 11/726 204/18639 0.053921568627451 1.38435828877005 0.173615155969158 0.599042493538282 GO:0017022 myosin binding 5/726 76/18639 0.0657894736842105 1.68904958677686 0.174254951468326 0.599042493538282 GO:0022853 active monoatomic ion transmembrane transporter activity 7/726 118/18639 0.0593220338983051 1.52300742400896 0.177123696804571 0.606615367627683 GO:0004601 peroxidase activity 4/726 57/18639 0.0701754385964912 1.80165289256198 0.181251197334815 0.614038969022705 GO:0000339 RNA cap binding 2/726 20/18639 0.1 2.56735537190083 0.181987400259199 0.614038969022705 GO:0016505 peptidase activator activity involved in apoptotic process 2/726 20/18639 0.1 2.56735537190083 0.181987400259199 0.614038969022705 GO:0030742 GTP-dependent protein binding 2/726 20/18639 0.1 2.56735537190083 0.181987400259199 0.614038969022705 GO:0005109 frizzled binding 3/726 38/18639 0.0789473684210526 2.02685950413223 0.183393314669492 0.614232756117307 GO:0042162 telomeric DNA binding 3/726 38/18639 0.0789473684210526 2.02685950413223 0.183393314669492 0.614232756117307 GO:0061980 regulatory RNA binding 4/726 58/18639 0.0689655172413793 1.77058991165574 0.189136720588072 0.631148543793897 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/726 39/18639 0.0769230769230769 1.97488874761602 0.193336824875738 0.63457505503266 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/726 39/18639 0.0769230769230769 1.97488874761602 0.193336824875738 0.63457505503266 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/726 21/18639 0.0952380952380952 2.44510035419126 0.196255812102587 0.63457505503266 GO:0005123 death receptor binding 2/726 21/18639 0.0952380952380952 2.44510035419126 0.196255812102587 0.63457505503266 GO:0010314 phosphatidylinositol-5-phosphate binding 2/726 21/18639 0.0952380952380952 2.44510035419126 0.196255812102587 0.63457505503266 GO:0035613 RNA stem-loop binding 2/726 21/18639 0.0952380952380952 2.44510035419126 0.196255812102587 0.63457505503266 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/726 21/18639 0.0952380952380952 2.44510035419126 0.196255812102587 0.63457505503266 GO:0015459 potassium channel regulator activity 4/726 59/18639 0.0677966101694915 1.7405799131531 0.197129243220903 0.63457505503266 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/726 59/18639 0.0677966101694915 1.7405799131531 0.197129243220903 0.63457505503266 GO:0070888 E-box binding 4/726 59/18639 0.0677966101694915 1.7405799131531 0.197129243220903 0.63457505503266 GO:0003713 transcription coactivator activity 13/726 256/18639 0.05078125 1.30373514979339 0.200537156012631 0.64327235608277 GO:0030331 nuclear estrogen receptor binding 3/726 40/18639 0.075 1.92551652892562 0.203410415614368 0.650199609209437 GO:0030971 receptor tyrosine kinase binding 5/726 81/18639 0.0617283950617284 1.58478726660545 0.208066438861777 0.662757083227547 GO:0008093 cytoskeletal anchor activity 2/726 22/18639 0.0909090909090909 2.33395942900075 0.21065504454441 0.664037181937568 GO:0061133 endopeptidase activator activity 2/726 22/18639 0.0909090909090909 2.33395942900075 0.21065504454441 0.664037181937568 GO:0140035 ubiquitin-like protein reader activity 2/726 22/18639 0.0909090909090909 2.33395942900075 0.21065504454441 0.664037181937568 GO:0016836 hydro-lyase activity 4/726 61/18639 0.0655737704918033 1.68351171927923 0.213411088371876 0.666408960727422 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/726 41/18639 0.0731707317073171 1.87855271114695 0.213601993998252 0.666408960727422 GO:0042287 MHC protein binding 3/726 41/18639 0.0731707317073171 1.87855271114695 0.213601993998252 0.666408960727422 GO:0015085 calcium ion transmembrane transporter activity 8/726 147/18639 0.054421768707483 1.39720020239501 0.215163086602983 0.66898829998402 GO:0019894 kinesin binding 3/726 42/18639 0.0714285714285714 1.83382526564345 0.223899700407389 0.683715566016291 GO:0031492 nucleosomal DNA binding 3/726 42/18639 0.0714285714285714 1.83382526564345 0.223899700407389 0.683715566016291 GO:0005158 insulin receptor binding 2/726 23/18639 0.0869565217391304 2.23248293208768 0.225153314824245 0.683715566016291 GO:0005212 structural constituent of eye lens 2/726 23/18639 0.0869565217391304 2.23248293208768 0.225153314824245 0.683715566016291 GO:0016917 GABA receptor activity 2/726 23/18639 0.0869565217391304 2.23248293208768 0.225153314824245 0.683715566016291 GO:0043274 phospholipase binding 2/726 23/18639 0.0869565217391304 2.23248293208768 0.225153314824245 0.683715566016291 GO:0099186 structural constituent of postsynapse 2/726 23/18639 0.0869565217391304 2.23248293208768 0.225153314824245 0.683715566016291 GO:0005507 copper ion binding 4/726 63/18639 0.0634920634920635 1.63006690279418 0.230048353585211 0.696259302711386 GO:0008013 beta-catenin binding 6/726 106/18639 0.0566037735849057 1.45322002183066 0.232043699043459 0.698139227269173 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 7/726 128/18639 0.0546875 1.40402246900826 0.232202179871086 0.698139227269173 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/726 43/18639 0.0697674418604651 1.79117816644244 0.234291928432058 0.699803104267558 GO:0048156 tau protein binding 3/726 43/18639 0.0697674418604651 1.79117816644244 0.234291928432058 0.699803104267558 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/726 24/18639 0.0833333333333333 2.13946280991736 0.239721111324999 0.711354828720112 GO:0050699 WW domain binding 2/726 24/18639 0.0833333333333333 2.13946280991736 0.239721111324999 0.711354828720112 GO:0003954 NADH dehydrogenase activity 3/726 44/18639 0.0681818181818182 1.75046957175056 0.244767342150523 0.721627989317561 GO:0030547 signaling receptor inhibitor activity 3/726 44/18639 0.0681818181818182 1.75046957175056 0.244767342150523 0.721627989317561 GO:0008483 transaminase activity 2/726 25/18639 0.08 2.05388429752066 0.254331065272096 0.742614104047692 GO:0015271 outward rectifier potassium channel activity 2/726 25/18639 0.08 2.05388429752066 0.254331065272096 0.742614104047692 GO:0042974 nuclear retinoic acid receptor binding 2/726 25/18639 0.08 2.05388429752066 0.254331065272096 0.742614104047692 GO:0042054 histone methyltransferase activity 4/726 67/18639 0.0597014925373134 1.53274947576169 0.264197419227629 0.766750784420763 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/726 46/18639 0.0652173913043478 1.67436219906576 0.265923822066574 0.766750784420763 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/726 89/18639 0.0561797752808989 1.44233447859597 0.265964048163514 0.766750784420763 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/726 89/18639 0.0561797752808989 1.44233447859597 0.265964048163514 0.766750784420763 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/726 26/18639 0.0769230769230769 1.97488874761602 0.268957828959909 0.770504975416595 GO:0050750 low-density lipoprotein particle receptor binding 2/726 26/18639 0.0769230769230769 1.97488874761602 0.268957828959909 0.770504975416595 GO:0032934 sterol binding 4/726 68/18639 0.0588235294117647 1.5102090422946 0.272882523615454 0.778486380511962 GO:0140793 histone H2AXY142 phosphatase activity 5/726 90/18639 0.0555555555555556 1.4263085399449 0.273452954735267 0.778486380511962 GO:0043495 protein-membrane adaptor activity 3/726 47/18639 0.0638297872340425 1.63873747142606 0.276583691077015 0.78250851730174 GO:0140938 histone H3 methyltransferase activity 3/726 47/18639 0.0638297872340425 1.63873747142606 0.276583691077015 0.78250851730174 GO:0016279 protein-lysine N-methyltransferase activity 4/726 69/18639 0.0579710144927536 1.48832195472512 0.28161523683569 0.7942770302084 GO:0004364 glutathione transferase activity 2/726 27/18639 0.0740740740740741 1.90174471992654 0.28357796019269 0.794890836109356 GO:0005104 fibroblast growth factor receptor binding 2/726 27/18639 0.0740740740740741 1.90174471992654 0.28357796019269 0.794890836109356 GO:0000287 magnesium ion binding 11/726 230/18639 0.0478260869565217 1.22786561264822 0.285829484211655 0.798744356186557 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/726 48/18639 0.0625 1.60459710743802 0.287284370424567 0.800354928002386 GO:0016278 lysine N-methyltransferase activity 4/726 70/18639 0.0571428571428571 1.46706021251476 0.290389931376639 0.806540327695482 GO:0046966 nuclear thyroid hormone receptor binding 2/726 28/18639 0.0714285714285714 1.83382526564345 0.298169812641655 0.816720360159543 GO:0009055 electron transfer activity 6/726 116/18639 0.0517241379310345 1.32794243374181 0.298230477948641 0.816720360159543 GO:0042562 hormone binding 5/726 94/18639 0.0531914893617021 1.36561455952172 0.303809273326799 0.816720360159543 GO:0005125 cytokine activity 11/726 234/18639 0.047008547008547 1.20687645687646 0.304800434437476 0.816720360159543 GO:1990782 protein tyrosine kinase binding 6/726 117/18639 0.0512820512820513 1.31659249841068 0.305056478430511 0.816720360159543 GO:0043539 protein serine/threonine kinase activator activity 4/726 73/18639 0.0547945205479452 1.40677006679497 0.316910992867039 0.816720360159543 GO:0015399 primary active transmembrane transporter activity 8/726 166/18639 0.0481927710843374 1.2372796973016 0.320281602455736 0.816720360159543 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/726 30/18639 0.0666666666666667 1.71157024793388 0.3271904565001 0.816720360159543 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/726 30/18639 0.0666666666666667 1.71157024793388 0.3271904565001 0.816720360159543 GO:0070566 adenylyltransferase activity 2/726 30/18639 0.0666666666666667 1.71157024793388 0.3271904565001 0.816720360159543 GO:0098918 structural constituent of synapse 2/726 30/18639 0.0666666666666667 1.71157024793388 0.3271904565001 0.816720360159543 GO:0000182 rDNA binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0003796 lysozyme activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0005381 iron ion transmembrane transporter activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0008140 cAMP response element binding protein binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0008519 ammonium channel activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0015203 polyamine transmembrane transporter activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0015279 store-operated calcium channel activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0031434 mitogen-activated protein kinase kinase binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0032052 bile acid binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0032356 oxidized DNA binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0035256 G protein-coupled glutamate receptor binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0035374 chondroitin sulfate binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0042975 peroxisome proliferator activated receptor binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0043121 neurotrophin binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0043295 glutathione binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0045322 unmethylated CpG binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0050815 phosphoserine residue binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0051864 histone H3K36 demethylase activity 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0051880 G-quadruplex DNA binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0071723 lipopeptide binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0097177 mitochondrial ribosome binding 1/726 10/18639 0.1 2.56735537190083 0.327929758923318 0.816720360159543 GO:0030159 signaling receptor complex adaptor activity 3/726 52/18639 0.0576923076923077 1.48116656071202 0.330304067156477 0.816720360159543 GO:0004725 protein tyrosine phosphatase activity 5/726 98/18639 0.0510204081632653 1.30987518974532 0.334635629174408 0.816720360159543 GO:0005249 voltage-gated potassium channel activity 5/726 98/18639 0.0510204081632653 1.30987518974532 0.334635629174408 0.816720360159543 GO:0008170 N-methyltransferase activity 5/726 98/18639 0.0510204081632653 1.30987518974532 0.334635629174408 0.816720360159543 GO:0019003 GDP binding 4/726 75/18639 0.0533333333333333 1.36925619834711 0.334702689325697 0.816720360159543 GO:0017147 Wnt-protein binding 2/726 31/18639 0.0645161290322581 1.65635830445215 0.341584025026957 0.816720360159543 GO:0070273 phosphatidylinositol-4-phosphate binding 2/726 31/18639 0.0645161290322581 1.65635830445215 0.341584025026957 0.816720360159543 GO:0008236 serine-type peptidase activity 9/726 194/18639 0.0463917525773196 1.19104115191275 0.344192061641478 0.816720360159543 GO:0003925 G protein activity 3/726 54/18639 0.0555555555555556 1.4263085399449 0.351819636648091 0.816720360159543 GO:0015485 cholesterol binding 3/726 54/18639 0.0555555555555556 1.4263085399449 0.351819636648091 0.816720360159543 GO:0051287 NAD binding 3/726 54/18639 0.0555555555555556 1.4263085399449 0.351819636648091 0.816720360159543 GO:0002162 dystroglycan binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0003953 NAD+ nucleosidase activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0008503 benzodiazepine receptor activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0010854 adenylate cyclase regulator activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0015217 ADP transmembrane transporter activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0019215 intermediate filament binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0019864 IgG binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0035252 UDP-xylosyltransferase activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0042285 xylosyltransferase activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0045294 alpha-catenin binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0047676 arachidonate-CoA ligase activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0048185 activin binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0070697 activin receptor binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0070990 snRNP binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0140537 transcription regulator activator activity 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:1900750 oligopeptide binding 1/726 11/18639 0.0909090909090909 2.33395942900075 0.354121341671811 0.816720360159543 GO:0017171 serine hydrolase activity 9/726 198/18639 0.0454545454545455 1.16697971450038 0.366282932846617 0.828624519185499 GO:0019956 chemokine binding 2/726 33/18639 0.0606060606060606 1.55597295266717 0.370060317925704 0.828624519185499 GO:0071889 14-3-3 protein binding 2/726 33/18639 0.0606060606060606 1.55597295266717 0.370060317925704 0.828624519185499 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 3/726 56/18639 0.0535714285714286 1.37536894923259 0.373252236546892 0.828624519185499 GO:0004252 serine-type endopeptidase activity 8/726 176/18639 0.0454545454545455 1.16697971450038 0.3791513746913 0.828624519185499 GO:0000340 RNA 7-methylguanosine cap binding 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0003720 telomerase activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0005078 MAP-kinase scaffold activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0005095 GTPase inhibitor activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0005165 neurotrophin receptor binding 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0008504 monoamine transmembrane transporter activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0010853 cyclase activator activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0015368 calcium:monoatomic cation antiporter activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0016208 AMP binding 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0031543 peptidyl-proline dioxygenase activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0035259 nuclear glucocorticoid receptor binding 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0035497 cAMP response element binding 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0070008 serine-type exopeptidase activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0070679 inositol 1,4,5 trisphosphate binding 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:1990817 poly(A) RNA polymerase activity 1/726 12/18639 0.0833333333333333 2.13946280991736 0.37929355049435 0.828624519185499 GO:0008376 acetylgalactosaminyltransferase activity 2/726 34/18639 0.0588235294117647 1.5102090422946 0.384116041954537 0.832456571974307 GO:0015020 glucuronosyltransferase activity 2/726 34/18639 0.0588235294117647 1.5102090422946 0.384116041954537 0.832456571974307 GO:0035591 signaling adaptor activity 6/726 129/18639 0.0465116279069767 1.19411877762829 0.388414424051055 0.832456571974307 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/726 58/18639 0.0517241379310345 1.32794243374181 0.394543446785353 0.832456571974307 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/726 130/18639 0.0461538461538462 1.18493324856961 0.395409155442912 0.832456571974307 GO:0005262 calcium channel activity 6/726 131/18639 0.0458015267175573 1.1758879565958 0.402400697276557 0.832456571974307 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0003964 RNA-directed DNA polymerase activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0004465 lipoprotein lipase activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0005035 death receptor activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0005172 vascular endothelial growth factor receptor binding 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0017154 semaphorin receptor activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0031432 titin binding 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0043560 insulin receptor substrate binding 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0046974 histone H3K9 methyltransferase activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0070123 transforming growth factor beta receptor activity, type III 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0140333 glycerophospholipid flippase activity 1/726 13/18639 0.0769230769230769 1.97488874761602 0.403486006732128 0.832456571974307 GO:0031593 polyubiquitin modification-dependent protein binding 3/726 59/18639 0.0508474576271186 1.30543493486483 0.405119207690592 0.832456571974307 GO:0141003 histone H2AX kinase activity 15/726 354/18639 0.0423728813559322 1.08786244572069 0.406432872760144 0.832456571974307 GO:0004175 endopeptidase activity 17/726 405/18639 0.0419753086419753 1.0776553412917 0.410965582287628 0.832456571974307 GO:0004033 aldo-keto reductase (NADPH) activity 2/726 36/18639 0.0555555555555556 1.4263085399449 0.411804049287754 0.832456571974307 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/726 36/18639 0.0555555555555556 1.4263085399449 0.411804049287754 0.832456571974307 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/726 36/18639 0.0555555555555556 1.4263085399449 0.411804049287754 0.832456571974307 GO:0051117 ATPase binding 4/726 84/18639 0.0476190476190476 1.22255017709563 0.414734601450834 0.832456571974307 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/726 60/18639 0.05 1.28367768595041 0.415640075617438 0.832456571974307 GO:0140996 histone H3 kinase activity 15/726 357/18639 0.0420168067226891 1.07872074449615 0.419174898510406 0.832456571974307 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 20/726 484/18639 0.0413223140495868 1.0608906495458 0.425399515580269 0.832456571974307 GO:0042805 actinin binding 2/726 37/18639 0.0540540540540541 1.38775966048693 0.425416155628699 0.832456571974307 GO:0070001 aspartic-type peptidase activity 2/726 37/18639 0.0540540540540541 1.38775966048693 0.425416155628699 0.832456571974307 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/726 61/18639 0.0491803278688525 1.26263378945942 0.426100195647381 0.832456571974307 GO:0005161 platelet-derived growth factor receptor binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0005347 ATP transmembrane transporter activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0005545 1-phosphatidylinositol binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0008191 metalloendopeptidase inhibitor activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0008195 phosphatidate phosphatase activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0008494 translation activator activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0008559 ABC-type xenobiotic transporter activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0019763 immunoglobulin receptor activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0032036 myosin heavy chain binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0042043 neurexin family protein binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0044548 S100 protein binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0061665 SUMO ligase activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0061783 peptidoglycan muralytic activity 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0070742 C2H2 zinc finger domain binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0071933 Arp2/3 complex binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:1990825 sequence-specific mRNA binding 1/726 14/18639 0.0714285714285714 1.83382526564345 0.426736793756313 0.832456571974307 GO:0004222 metalloendopeptidase activity 5/726 110/18639 0.0454545454545455 1.16697971450038 0.427800706731212 0.832748811607123 GO:0035173 histone kinase activity 15/726 360/18639 0.0416666666666667 1.06973140495868 0.431929873818591 0.835049463518792 GO:0050660 flavin adenine dinucleotide binding 4/726 86/18639 0.0465116279069767 1.19411877762829 0.432303162560644 0.835049463518792 GO:0015078 proton transmembrane transporter activity 8/726 185/18639 0.0432432432432432 1.11020772838955 0.432649118310505 0.835049463518792 GO:1901981 phosphatidylinositol phosphate binding 8/726 185/18639 0.0432432432432432 1.11020772838955 0.432649118310505 0.835049463518792 GO:0099094 ligand-gated monoatomic cation channel activity 6/726 136/18639 0.0441176470588235 1.13265678172095 0.437236762708815 0.838348714367447 GO:0140789 histone phosphatase activity 6/726 136/18639 0.0441176470588235 1.13265678172095 0.437236762708815 0.838348714367447 GO:0000146 microfilament motor activity 2/726 38/18639 0.0526315789473684 1.35123966942149 0.438861869015322 0.838348714367447 GO:0000774 adenyl-nucleotide exchange factor activity 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0004089 carbonate dehydratase activity 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0004467 long-chain fatty acid-CoA ligase activity 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0004559 alpha-mannosidase activity 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0030553 cGMP binding 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0031005 filamin binding 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0033130 acetylcholine receptor binding 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0042809 nuclear vitamin D receptor binding 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0051371 muscle alpha-actinin binding 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0140776 protein-containing complex destabilizing activity 1/726 15/18639 0.0666666666666667 1.71157024793388 0.449082516587612 0.838348714367447 GO:0001216 DNA-binding transcription activator activity 20/726 491/18639 0.0407331975560081 1.04576593560115 0.451075732893545 0.839860045061835 GO:0140713 histone chaperone activity 7/726 164/18639 0.0426829268292683 1.09582241483572 0.457215358197545 0.839860045061835 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/726 40/18639 0.05 1.28367768595041 0.465224181307525 0.839860045061835 GO:0061791 GTPase motor activity 2/726 40/18639 0.05 1.28367768595041 0.465224181307525 0.839860045061835 GO:1990606 membrane scission GTPase motor activity 2/726 40/18639 0.05 1.28367768595041 0.465224181307525 0.839860045061835 GO:0017124 SH3 domain binding 5/726 115/18639 0.0434782608695652 1.11624146604384 0.466036431948701 0.839860045061835 GO:0016757 glycosyltransferase activity 11/726 267/18639 0.0411985018726592 1.05771195097038 0.468158576125505 0.839860045061835 GO:0000062 fatty-acyl-CoA binding 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0015378 sodium:chloride symporter activity 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0015562 efflux transmembrane transporter activity 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0015923 mannosidase activity 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0017070 U6 snRNA binding 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0034450 ubiquitin-ubiquitin ligase activity 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0140327 flippase activity 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0140328 floppase activity 1/726 16/18639 0.0625 1.60459710743802 0.470558359207746 0.839860045061835 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/726 91/18639 0.043956043956044 1.12850785578058 0.47552505213488 0.839860045061835 GO:0001530 lipopolysaccharide binding 2/726 41/18639 0.0487804878048781 1.25236847409796 0.478127883220821 0.839860045061835 GO:0001727 lipid kinase activity 2/726 41/18639 0.0487804878048781 1.25236847409796 0.478127883220821 0.839860045061835 GO:0043178 alcohol binding 4/726 92/18639 0.0434782608695652 1.11624146604384 0.484023545422055 0.839860045061835 GO:0022843 voltage-gated monoatomic cation channel activity 6/726 143/18639 0.041958041958042 1.07721204415419 0.485308607547565 0.839860045061835 GO:0005096 GTPase activator activity 11/726 271/18639 0.040590405904059 1.04209996645421 0.4879597576736 0.839860045061835 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0004550 nucleoside diphosphate kinase activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0005092 GDP-dissociation inhibitor activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0008429 phosphatidylethanolamine binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0009881 photoreceptor activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0016805 dipeptidase activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0019198 transmembrane receptor protein phosphatase activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0030169 low-density lipoprotein particle binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0030548 acetylcholine receptor regulator activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0031489 myosin V binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0032183 SUMO binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0045125 bioactive lipid receptor activity 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0051787 misfolded protein binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0070403 NAD+ binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:1901567 fatty acid derivative binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:1990226 histone methyltransferase binding 1/726 17/18639 0.0588235294117647 1.5102090422946 0.491198139652099 0.839860045061835 GO:0042393 histone binding 10/726 247/18639 0.0404858299595142 1.03941513032422 0.495926201578863 0.839860045061835 GO:0030145 manganese ion binding 3/726 68/18639 0.0441176470588235 1.13265678172095 0.497191261116131 0.839860045061835 GO:0016410 N-acyltransferase activity 4/726 94/18639 0.0425531914893617 1.09249164761737 0.500851289389141 0.839860045061835 GO:0016758 hexosyltransferase activity 8/726 197/18639 0.0406091370558376 1.04258086168561 0.503011105255368 0.839860045061835 GO:0008375 acetylglucosaminyltransferase activity 2/726 43/18639 0.0465116279069767 1.19411877762829 0.503353797919026 0.839860045061835 GO:0008080 N-acetyltransferase activity 3/726 69/18639 0.0434782608695652 1.11624146604384 0.506990171310696 0.839860045061835 GO:0098960 postsynaptic neurotransmitter receptor activity 3/726 69/18639 0.0434782608695652 1.11624146604384 0.506990171310696 0.839860045061835 GO:0008276 protein methyltransferase activity 4/726 95/18639 0.0421052631578947 1.08099173553719 0.509175276725627 0.839860045061835 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0004706 JUN kinase kinase kinase activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0004970 glutamate-gated receptor activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0008525 phosphatidylcholine transporter activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0015373 monoatomic anion:sodium symporter activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0016854 racemase and epimerase activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0022851 GABA-gated chloride ion channel activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0031690 adrenergic receptor binding 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0035615 clathrin adaptor activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0099602 neurotransmitter receptor regulator activity 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:1990381 ubiquitin-specific protease binding 1/726 18/18639 0.0555555555555556 1.4263085399449 0.511034362969282 0.839860045061835 GO:0019205 nucleobase-containing compound kinase activity 2/726 44/18639 0.0454545454545455 1.16697971450038 0.515667438669907 0.839860045061835 GO:0097110 scaffold protein binding 3/726 70/18639 0.0428571428571429 1.10029515938607 0.516688689516698 0.839860045061835 GO:0016829 lyase activity 8/726 200/18639 0.04 1.02694214876033 0.520216925072782 0.839860045061835 GO:0001217 DNA-binding transcription repressor activity 11/726 278/18639 0.039568345323741 1.01586003924133 0.52218673833441 0.839860045061835 GO:0004721 phosphoprotein phosphatase activity 7/726 175/18639 0.04 1.02694214876033 0.52563275789309 0.839860045061835 GO:0008009 chemokine activity 2/726 45/18639 0.0444444444444444 1.14104683195592 0.527776859494204 0.839860045061835 GO:0046915 transition metal ion transmembrane transporter activity 2/726 45/18639 0.0444444444444444 1.14104683195592 0.527776859494204 0.839860045061835 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0004890 GABA-A receptor activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0008301 DNA binding, bending 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0015245 fatty acid transmembrane transporter activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0030506 ankyrin binding 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0042577 lipid phosphatase activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0042800 histone H3K4 methyltransferase activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0042834 peptidoglycan binding 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0046624 sphingolipid transporter activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0050145 nucleoside monophosphate kinase activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0070003 threonine-type peptidase activity 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0097001 ceramide binding 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0120227 acyl-CoA binding 1/726 19/18639 0.0526315789473684 1.35123966942149 0.530098272130137 0.839860045061835 GO:0005267 potassium channel activity 5/726 124/18639 0.0403225806451613 1.03522394028259 0.532643187385751 0.842426985604894 GO:0042379 chemokine receptor binding 3/726 72/18639 0.0416666666666667 1.06973140495868 0.535772450242542 0.845907629412401 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/726 46/18639 0.0434782608695652 1.11624146604384 0.53967927028637 0.848235188685102 GO:0030291 protein serine/threonine kinase inhibitor activity 2/726 46/18639 0.0434782608695652 1.11624146604384 0.53967927028637 0.848235188685102 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/726 73/18639 0.0410958904109589 1.05507755009623 0.545152226987206 0.848235188685102 GO:0001614 purinergic nucleotide receptor activity 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0005326 neurotransmitter transmembrane transporter activity 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0010851 cyclase regulator activity 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0016502 nucleotide receptor activity 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0031418 L-ascorbic acid binding 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0061608 nuclear import signal receptor activity 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0140939 histone H4 methyltransferase activity 1/726 20/18639 0.05 1.28367768595041 0.54841989696545 0.848235188685102 GO:0005504 fatty acid binding 2/726 47/18639 0.0425531914893617 1.09249164761737 0.551372407140118 0.849915842478254 GO:0061733 protein-lysine-acetyltransferase activity 2/726 47/18639 0.0425531914893617 1.09249164761737 0.551372407140118 0.849915842478254 GO:0016887 ATP hydrolysis activity 16/726 417/18639 0.0383693045563549 0.985076401688566 0.560884731060417 0.861782261472764 GO:0031490 chromatin DNA binding 5/726 128/18639 0.0390625 1.00287319214876 0.561027690292456 0.861782261472764 GO:0032266 phosphatidylinositol-3-phosphate binding 2/726 48/18639 0.0416666666666667 1.06973140495868 0.562854495692969 0.861782261472764 GO:0140693 molecular condensate scaffold activity 2/726 48/18639 0.0416666666666667 1.06973140495868 0.562854495692969 0.861782261472764 GO:0004386 helicase activity 6/726 155/18639 0.0387096774193548 0.993814982671288 0.564275094790502 0.862293645821118 GO:0051428 peptide hormone receptor binding 1/726 21/18639 0.0476190476190476 1.22255017709563 0.566028101208593 0.862293645821118 GO:0140312 cargo adaptor activity 1/726 21/18639 0.0476190476190476 1.22255017709563 0.566028101208593 0.862293645821118 GO:0005261 monoatomic cation channel activity 13/726 341/18639 0.0381231671554252 0.978757179903541 0.57155245953421 0.864843384919306 GO:0035254 glutamate receptor binding 2/726 49/18639 0.0408163265306122 1.04790015179626 0.574124216521442 0.864843384919306 GO:0060590 ATPase regulator activity 2/726 49/18639 0.0408163265306122 1.04790015179626 0.574124216521442 0.864843384919306 GO:0003724 RNA helicase activity 3/726 77/18639 0.038961038961039 1.00026832671461 0.581537134817246 0.864843384919306 GO:0005243 gap junction channel activity 1/726 22/18639 0.0454545454545455 1.16697971450038 0.582950627716412 0.864843384919306 GO:0008970 phospholipase A1 activity 1/726 22/18639 0.0454545454545455 1.16697971450038 0.582950627716412 0.864843384919306 GO:0015377 chloride:monoatomic cation symporter activity 1/726 22/18639 0.0454545454545455 1.16697971450038 0.582950627716412 0.864843384919306 GO:0050321 tau-protein kinase activity 1/726 22/18639 0.0454545454545455 1.16697971450038 0.582950627716412 0.864843384919306 GO:0070034 telomerase RNA binding 1/726 22/18639 0.0454545454545455 1.16697971450038 0.582950627716412 0.864843384919306 GO:0032813 tumor necrosis factor receptor superfamily binding 2/726 50/18639 0.04 1.02694214876033 0.585180672483153 0.864843384919306 GO:0022836 gated channel activity 12/726 318/18639 0.0377358490566038 0.968813347887104 0.586145206881904 0.864843384919306 GO:0019199 transmembrane receptor protein kinase activity 3/726 78/18639 0.0384615384615385 0.98744437380801 0.590340407221482 0.864843384919306 GO:0015276 ligand-gated monoatomic ion channel activity 7/726 186/18639 0.0376344086021505 0.966209010930419 0.590532578543004 0.864843384919306 GO:0015079 potassium ion transmembrane transporter activity 6/726 160/18639 0.0375 0.96275826446281 0.595429464895059 0.864843384919306 GO:0005272 sodium channel activity 2/726 51/18639 0.0392156862745098 1.0068060281964 0.596023357906943 0.864843384919306 GO:0030544 Hsp70 protein binding 2/726 51/18639 0.0392156862745098 1.0068060281964 0.596023357906943 0.864843384919306 GO:0008186 ATP-dependent activity, acting on RNA 3/726 79/18639 0.0379746835443038 0.974945077937023 0.599023409998559 0.864843384919306 GO:0033293 monocarboxylic acid binding 3/726 79/18639 0.0379746835443038 0.974945077937023 0.599023409998559 0.864843384919306 GO:0000295 adenine nucleotide transmembrane transporter activity 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:0016849 phosphorus-oxygen lyase activity 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:0031681 G-protein beta-subunit binding 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:0140103 catalytic activity, acting on a glycoprotein 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/726 23/18639 0.0434782608695652 1.11624146604384 0.599214141938783 0.864843384919306 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/726 268/18639 0.0373134328358209 0.957968422351055 0.600260215726876 0.864843384919306 GO:0022834 ligand-gated channel activity 7/726 188/18639 0.0372340425531915 0.955930191665201 0.60185041730183 0.864843384919306 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/726 52/18639 0.0384615384615385 0.98744437380801 0.606652129536961 0.864843384919306 GO:0001664 G protein-coupled receptor binding 11/726 297/18639 0.037037037037037 0.950872359963269 0.61085376266346 0.864843384919306 GO:0005496 steroid binding 4/726 108/18639 0.037037037037037 0.950872359963269 0.610905549347687 0.864843384919306 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/726 24/18639 0.0416666666666667 1.06973140495868 0.6148442737046 0.864843384919306 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/726 24/18639 0.0416666666666667 1.06973140495868 0.6148442737046 0.864843384919306 GO:0004806 triacylglycerol lipase activity 1/726 24/18639 0.0416666666666667 1.06973140495868 0.6148442737046 0.864843384919306 GO:0015295 solute:proton symporter activity 1/726 24/18639 0.0416666666666667 1.06973140495868 0.6148442737046 0.864843384919306 GO:0030215 semaphorin receptor binding 1/726 24/18639 0.0416666666666667 1.06973140495868 0.6148442737046 0.864843384919306 GO:0035035 histone acetyltransferase binding 1/726 24/18639 0.0416666666666667 1.06973140495868 0.6148442737046 0.864843384919306 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/726 24/18639 0.0416666666666667 1.06973140495868 0.6148442737046 0.864843384919306 GO:0016779 nucleotidyltransferase activity 5/726 136/18639 0.0367647058823529 0.943880651434127 0.61504714825574 0.864843384919306 GO:0033192 calmodulin-dependent protein phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:0140791 histone H2AXS140 phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/726 81/18639 0.037037037037037 0.950872359963269 0.616023865799871 0.864843384919306 GO:0008146 sulfotransferase activity 2/726 53/18639 0.0377358490566038 0.968813347887104 0.617067179141107 0.864843384919306 GO:0017046 peptide hormone binding 2/726 53/18639 0.0377358490566038 0.968813347887104 0.617067179141107 0.864843384919306 GO:0034212 protein N-acetyltransferase activity 2/726 53/18639 0.0377358490566038 0.968813347887104 0.617067179141107 0.864843384919306 GO:0051018 protein kinase A binding 2/726 53/18639 0.0377358490566038 0.968813347887104 0.617067179141107 0.864843384919306 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/726 53/18639 0.0377358490566038 0.968813347887104 0.617067179141107 0.864843384919306 GO:0004674 protein serine/threonine kinase activity 16/726 433/18639 0.0369515011547344 0.94867634989407 0.621714307253255 0.865471514150288 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/726 82/18639 0.0365853658536585 0.939276355573473 0.624339364376671 0.865471514150288 GO:0033549 MAP kinase phosphatase activity 3/726 82/18639 0.0365853658536585 0.939276355573473 0.624339364376671 0.865471514150288 GO:0000030 mannosyltransferase activity 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0004709 MAP kinase kinase kinase activity 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0015645 fatty acid ligase activity 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0015662 P-type ion transporter activity 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0017025 TBP-class protein binding 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0017056 structural constituent of nuclear pore 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0120515 fatty acid-CoA ligase activity 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0140358 P-type transmembrane transporter activity 1/726 25/18639 0.04 1.02694214876033 0.629865657389288 0.865471514150288 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/726 83/18639 0.036144578313253 0.927959772976202 0.63253067044226 0.866519459808871 GO:0005254 chloride channel activity 3/726 83/18639 0.036144578313253 0.927959772976202 0.63253067044226 0.866519459808871 GO:0070851 growth factor receptor binding 5/726 139/18639 0.0359712230215827 0.923509126583031 0.634269327236025 0.867596632300328 GO:0017018 myosin phosphatase activity 3/726 84/18639 0.0357142857142857 0.916912632821724 0.640597191516017 0.868282685132555 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0005227 calcium-activated cation channel activity 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0008066 glutamate receptor activity 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0015216 purine nucleotide transmembrane transporter activity 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0019865 immunoglobulin binding 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0030247 polysaccharide binding 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0034237 protein kinase A regulatory subunit binding 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0043548 phosphatidylinositol 3-kinase binding 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0052742 phosphatidylinositol kinase activity 1/726 26/18639 0.0384615384615385 0.98744437380801 0.644301970526463 0.868282685132555 GO:0020037 heme binding 5/726 142/18639 0.0352112676056338 0.903998370387615 0.652892651016525 0.871914505421425 GO:0001671 ATPase activator activity 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0008320 protein transmembrane transporter activity 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0008395 steroid hydroxylase activity 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0015252 proton channel activity 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0016405 CoA-ligase activity 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0035255 ionotropic glutamate receptor binding 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/726 27/18639 0.037037037037037 0.950872359963269 0.658175970923915 0.871914505421425 GO:0008081 phosphoric diester hydrolase activity 3/726 87/18639 0.0344827586206897 0.885294955827871 0.664044207753786 0.871914505421425 GO:0005244 voltage-gated monoatomic ion channel activity 6/726 173/18639 0.0346820809248555 0.890412267711269 0.670498588017112 0.871914505421425 GO:0008194 UDP-glycosyltransferase activity 5/726 145/18639 0.0344827586206897 0.885294955827871 0.670901573990398 0.871914505421425 GO:0005242 inward rectifier potassium channel activity 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0019789 SUMO transferase activity 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0045499 chemorepellent activity 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0046625 sphingolipid binding 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0050698 proteoglycan sulfotransferase activity 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0051393 alpha-actinin binding 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0051537 2 iron, 2 sulfur cluster binding 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0141052 histone H3 demethylase activity 1/726 28/18639 0.0357142857142857 0.916912632821724 0.671509532341777 0.871914505421425 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/726 88/18639 0.0340909090909091 0.875234785875282 0.671608402896129 0.871914505421425 GO:0035091 phosphatidylinositol binding 10/726 284/18639 0.0352112676056338 0.903998370387615 0.672278703574819 0.871914505421425 GO:0005216 monoatomic ion channel activity 16/726 448/18639 0.0357142857142857 0.916912632821724 0.674915950277393 0.871914505421425 GO:0004879 nuclear receptor activity 2/726 59/18639 0.0338983050847458 0.870289956576551 0.675116066918218 0.871914505421425 GO:0036002 pre-mRNA binding 2/726 59/18639 0.0338983050847458 0.870289956576551 0.675116066918218 0.871914505421425 GO:0070063 RNA polymerase binding 2/726 59/18639 0.0338983050847458 0.870289956576551 0.675116066918218 0.871914505421425 GO:0003823 antigen binding 6/726 174/18639 0.0344827586206897 0.885294955827871 0.675890105639638 0.871914505421425 GO:0022832 voltage-gated channel activity 6/726 175/18639 0.0342857142857143 0.880236127508855 0.681224686033007 0.871914505421425 GO:0001098 basal transcription machinery binding 2/726 60/18639 0.0333333333333333 0.855785123966942 0.684063514894107 0.871914505421425 GO:0001099 basal RNA polymerase II transcription machinery binding 2/726 60/18639 0.0333333333333333 0.855785123966942 0.684063514894107 0.871914505421425 GO:0098531 ligand-modulated transcription factor activity 2/726 60/18639 0.0333333333333333 0.855785123966942 0.684063514894107 0.871914505421425 GO:0004181 metallocarboxypeptidase activity 1/726 29/18639 0.0344827586206897 0.885294955827871 0.684323678788495 0.871914505421425 GO:0004629 phospholipase C activity 1/726 29/18639 0.0344827586206897 0.885294955827871 0.684323678788495 0.871914505421425 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/726 29/18639 0.0344827586206897 0.885294955827871 0.684323678788495 0.871914505421425 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/726 29/18639 0.0344827586206897 0.885294955827871 0.684323678788495 0.871914505421425 GO:0097472 cyclin-dependent protein kinase activity 1/726 29/18639 0.0344827586206897 0.885294955827871 0.684323678788495 0.871914505421425 GO:0106222 lncRNA binding 1/726 29/18639 0.0344827586206897 0.885294955827871 0.684323678788495 0.871914505421425 GO:0032182 ubiquitin-like protein binding 4/726 120/18639 0.0333333333333333 0.855785123966942 0.692351998815941 0.873473660970938 GO:0001965 G-protein alpha-subunit binding 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0015215 nucleotide transmembrane transporter activity 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0022839 monoatomic ion-gated channel activity 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0031624 ubiquitin conjugating enzyme binding 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0032452 histone demethylase activity 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0033612 receptor serine/threonine kinase binding 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0048019 receptor antagonist activity 1/726 30/18639 0.0333333333333333 0.855785123966942 0.696638617488094 0.873473660970938 GO:0003697 single-stranded DNA binding 4/726 121/18639 0.0330578512396694 0.848712519636637 0.698558014876285 0.873473660970938 GO:0015108 chloride transmembrane transporter activity 4/726 121/18639 0.0330578512396694 0.848712519636637 0.698558014876285 0.873473660970938 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/726 122/18639 0.0327868852459016 0.841755859639615 0.704673692375134 0.873473660970938 GO:0000510 H3-H4 histone complex chaperone activity 5/726 151/18639 0.033112582781457 0.850117672814843 0.70503459645227 0.873473660970938 GO:0140584 chromatin extrusion motor activity 5/726 151/18639 0.033112582781457 0.850117672814843 0.70503459645227 0.873473660970938 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/726 151/18639 0.033112582781457 0.850117672814843 0.70503459645227 0.873473660970938 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/726 151/18639 0.033112582781457 0.850117672814843 0.70503459645227 0.873473660970938 GO:0051213 dioxygenase activity 3/726 93/18639 0.032258064516129 0.828179152226073 0.707547964135566 0.873473660970938 GO:0005164 tumor necrosis factor receptor binding 1/726 31/18639 0.032258064516129 0.828179152226073 0.708473770570132 0.873473660970938 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/726 31/18639 0.032258064516129 0.828179152226073 0.708473770570132 0.873473660970938 GO:0016878 acid-thiol ligase activity 1/726 31/18639 0.032258064516129 0.828179152226073 0.708473770570132 0.873473660970938 GO:0140457 protein demethylase activity 1/726 31/18639 0.032258064516129 0.828179152226073 0.708473770570132 0.873473660970938 GO:0022824 transmitter-gated monoatomic ion channel activity 2/726 63/18639 0.0317460317460317 0.815033451397088 0.709697261897488 0.873473660970938 GO:0022835 transmitter-gated channel activity 2/726 63/18639 0.0317460317460317 0.815033451397088 0.709697261897488 0.873473660970938 GO:0015616 DNA translocase activity 5/726 152/18639 0.0328947368421053 0.84452479338843 0.71047638065803 0.873473660970938 GO:0046906 tetrapyrrole binding 5/726 152/18639 0.0328947368421053 0.84452479338843 0.71047638065803 0.873473660970938 GO:0140674 ATP-dependent histone chaperone activity 5/726 152/18639 0.0328947368421053 0.84452479338843 0.71047638065803 0.873473660970938 GO:0061775 cohesin loader activity 5/726 153/18639 0.0326797385620915 0.839005023497002 0.715847272477675 0.877886681177294 GO:0022884 macromolecule transmembrane transporter activity 1/726 32/18639 0.03125 0.802298553719008 0.719847805531766 0.877886681177294 GO:0042910 xenobiotic transmembrane transporter activity 1/726 32/18639 0.03125 0.802298553719008 0.719847805531766 0.877886681177294 GO:0043425 bHLH transcription factor binding 1/726 32/18639 0.03125 0.802298553719008 0.719847805531766 0.877886681177294 GO:0071813 lipoprotein particle binding 1/726 32/18639 0.03125 0.802298553719008 0.719847805531766 0.877886681177294 GO:0071814 protein-lipid complex binding 1/726 32/18639 0.03125 0.802298553719008 0.719847805531766 0.877886681177294 GO:0005506 iron ion binding 5/726 154/18639 0.0324675324675325 0.83355693892884 0.721147247592501 0.87829564512937 GO:0016407 acetyltransferase activity 3/726 96/18639 0.03125 0.802298553719008 0.727621305744993 0.884997342501586 GO:0030296 protein tyrosine kinase activator activity 1/726 33/18639 0.0303030303030303 0.777986476333584 0.730778664519456 0.887387435022052 GO:0140375 immune receptor activity 5/726 156/18639 0.032051282051282 0.822870311506675 0.731534537542877 0.887387435022052 GO:0004519 endonuclease activity 4/726 127/18639 0.031496062992126 0.808615865165615 0.733900578720573 0.888095302366625 GO:0030594 neurotransmitter receptor activity 3/726 97/18639 0.0309278350515464 0.794027434608503 0.734067796577463 0.888095302366625 GO:0031406 carboxylic acid binding 6/726 187/18639 0.0320855614973262 0.823750386706148 0.740719916741489 0.888990704130464 GO:0016791 phosphatase activity 9/726 273/18639 0.032967032967033 0.846380891835437 0.740849778427915 0.888990704130464 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/726 67/18639 0.0298507462686567 0.766374737880844 0.741146149008888 0.888990704130464 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/726 34/18639 0.0294117647058824 0.755104521147302 0.741283592475968 0.888990704130464 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/726 34/18639 0.0294117647058824 0.755104521147302 0.741283592475968 0.888990704130464 GO:0019825 oxygen binding 1/726 34/18639 0.0294117647058824 0.755104521147302 0.741283592475968 0.888990704130464 GO:0140658 ATP-dependent chromatin remodeler activity 5/726 158/18639 0.0316455696202532 0.812454231614186 0.741638787199948 0.888990704130464 GO:0005543 phospholipid binding 17/726 497/18639 0.03420523138833 0.878169845519397 0.743030609710924 0.889488679956179 GO:0005548 phospholipid transporter activity 2/726 68/18639 0.0294117647058824 0.755104521147302 0.748538721369275 0.891381564406729 GO:0043177 organic acid binding 6/726 189/18639 0.0317460317460317 0.815033451397088 0.749817703009331 0.891381564406729 GO:0005154 epidermal growth factor receptor binding 1/726 35/18639 0.0285714285714286 0.733530106257379 0.751379164196605 0.891381564406729 GO:0034061 DNA polymerase activity 1/726 35/18639 0.0285714285714286 0.733530106257379 0.751379164196605 0.891381564406729 GO:0043015 gamma-tubulin binding 1/726 35/18639 0.0285714285714286 0.733530106257379 0.751379164196605 0.891381564406729 GO:0061631 ubiquitin conjugating enzyme activity 1/726 35/18639 0.0285714285714286 0.733530106257379 0.751379164196605 0.891381564406729 GO:0003689 DNA clamp loader activity 5/726 160/18639 0.03125 0.802298553719008 0.751461077348373 0.891381564406729 GO:0043130 ubiquitin binding 3/726 100/18639 0.03 0.770206611570248 0.752685370205661 0.891672785770296 GO:0019902 phosphatase binding 6/726 190/18639 0.0315789473684211 0.810743801652893 0.754279020789898 0.892400244077399 GO:0002039 p53 binding 2/726 69/18639 0.0289855072463768 0.744160977362558 0.755749125848636 0.892979836119464 GO:0042578 phosphoric ester hydrolase activity 12/726 363/18639 0.0330578512396694 0.848712519636637 0.759143542252997 0.894328014290788 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/726 132/18639 0.0303030303030303 0.777986476333584 0.760898618805723 0.894328014290788 GO:0004190 aspartic-type endopeptidase activity 1/726 36/18639 0.0277777777777778 0.713154269972452 0.761081310336858 0.894328014290788 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/726 36/18639 0.0277777777777778 0.713154269972452 0.761081310336858 0.894328014290788 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/726 70/18639 0.0285714285714286 0.733530106257379 0.762780315152516 0.894328014290788 GO:0016782 transferase activity, transferring sulphur-containing groups 2/726 70/18639 0.0285714285714286 0.733530106257379 0.762780315152516 0.894328014290788 GO:0046873 metal ion transmembrane transporter activity 15/726 450/18639 0.0333333333333333 0.855785123966942 0.767565332089533 0.896346445641647 GO:0140299 molecular sensor activity 2/726 71/18639 0.028169014084507 0.723198696310092 0.769635288588016 0.896346445641647 GO:0004722 protein serine/threonine phosphatase activity 3/726 103/18639 0.029126213592233 0.747773409291503 0.770241292155165 0.896346445641647 GO:0005253 monoatomic anion channel activity 3/726 103/18639 0.029126213592233 0.747773409291503 0.770241292155165 0.896346445641647 GO:0022829 wide pore channel activity 1/726 37/18639 0.027027027027027 0.693879830243467 0.770405342412085 0.896346445641647 GO:0030551 cyclic nucleotide binding 1/726 37/18639 0.027027027027027 0.693879830243467 0.770405342412085 0.896346445641647 GO:0005501 retinoid binding 1/726 38/18639 0.0263157894736842 0.675619834710744 0.779365976828213 0.90331094769784 GO:0019840 isoprenoid binding 1/726 38/18639 0.0263157894736842 0.675619834710744 0.779365976828213 0.90331094769784 GO:0043531 ADP binding 1/726 38/18639 0.0263157894736842 0.675619834710744 0.779365976828213 0.90331094769784 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/726 167/18639 0.029940119760479 0.7686692730242 0.783645701667431 0.907117197228755 GO:0022804 active transmembrane transporter activity 15/726 457/18639 0.0328227571115974 0.842676817910556 0.786942667182407 0.909777626653772 GO:0003684 damaged DNA binding 2/726 74/18639 0.027027027027027 0.693879830243467 0.789173439671491 0.91120025797304 GO:0032451 demethylase activity 1/726 40/18639 0.025 0.641838842975207 0.796253080459792 0.918210830758064 GO:0051536 iron-sulfur cluster binding 2/726 76/18639 0.0263157894736842 0.675619834710744 0.801374181483605 0.919236960685055 GO:0004620 phospholipase activity 3/726 109/18639 0.0275229357798165 0.706611570247934 0.802294416852751 0.919236960685055 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/726 41/18639 0.024390243902439 0.626184237048982 0.804206210390767 0.919236960685055 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/726 41/18639 0.024390243902439 0.626184237048982 0.804206210390767 0.919236960685055 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/726 41/18639 0.024390243902439 0.626184237048982 0.804206210390767 0.919236960685055 GO:0140318 protein transporter activity 1/726 41/18639 0.024390243902439 0.626184237048982 0.804206210390767 0.919236960685055 GO:0140828 metal cation:monoatomic cation antiporter activity 1/726 41/18639 0.024390243902439 0.626184237048982 0.804206210390767 0.919236960685055 GO:0051540 metal cluster binding 2/726 77/18639 0.025974025974026 0.666845551143072 0.807236502728041 0.921544428552939 GO:0004402 histone acetyltransferase activity 1/726 42/18639 0.0238095238095238 0.611275088547816 0.811849305952456 0.92449339715336 GO:0004520 DNA endonuclease activity 1/726 42/18639 0.0238095238095238 0.611275088547816 0.811849305952456 0.92449339715336 GO:0019903 protein phosphatase binding 4/726 144/18639 0.0277777777777778 0.713154269972452 0.816973061734304 0.929166615780213 GO:0005245 voltage-gated calcium channel activity 1/726 43/18639 0.0232558139534884 0.597059388814146 0.81919443709611 0.930531336900942 GO:0043014 alpha-tubulin binding 1/726 44/18639 0.0227272727272727 0.583489857250188 0.82625320450137 0.937380659154107 GO:0140303 intramembrane lipid transporter activity 1/726 45/18639 0.0222222222222222 0.570523415977961 0.833036757796987 0.943901102429173 GO:0106310 protein serine kinase activity 11/726 361/18639 0.0304709141274238 0.782296650717703 0.836132446750674 0.945953364411476 GO:0008509 monoatomic anion transmembrane transporter activity 4/726 149/18639 0.0268456375838926 0.689222918631094 0.836924710994127 0.945953364411476 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 5/726 181/18639 0.0276243093922652 0.709214191132825 0.838215692613672 0.946238532801803 GO:0061749 forked DNA-dependent helicase activity 1/726 47/18639 0.0212765957446809 0.546245823808686 0.845820669725759 0.950114217164201 GO:0099095 ligand-gated monoatomic anion channel activity 1/726 47/18639 0.0212765957446809 0.546245823808686 0.845820669725759 0.950114217164201 GO:0140359 ABC-type transporter activity 1/726 47/18639 0.0212765957446809 0.546245823808686 0.845820669725759 0.950114217164201 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/726 47/18639 0.0212765957446809 0.546245823808686 0.845820669725759 0.950114217164201 GO:0003774 cytoskeletal motor activity 4/726 153/18639 0.0261437908496732 0.671204018797602 0.851547189337337 0.951013918444715 GO:0009378 four-way junction helicase activity 1/726 48/18639 0.0208333333333333 0.534865702479339 0.851841226620074 0.951013918444715 GO:0036121 double-stranded DNA helicase activity 1/726 48/18639 0.0208333333333333 0.534865702479339 0.851841226620074 0.951013918444715 GO:0038187 pattern recognition receptor activity 1/726 48/18639 0.0208333333333333 0.534865702479339 0.851841226620074 0.951013918444715 GO:0043138 3'-5' DNA helicase activity 1/726 48/18639 0.0208333333333333 0.534865702479339 0.851841226620074 0.951013918444715 GO:0008528 G protein-coupled peptide receptor activity 3/726 122/18639 0.0245901639344262 0.631316894729711 0.858991889118707 0.957823269262108 GO:0015605 organophosphate ester transmembrane transporter activity 1/726 50/18639 0.02 0.513471074380165 0.863187126749115 0.96015076003473 GO:0048020 CCR chemokine receptor binding 1/726 50/18639 0.02 0.513471074380165 0.863187126749115 0.96015076003473 GO:0005021 vascular endothelial growth factor receptor activity 1/726 51/18639 0.0196078431372549 0.503403014098201 0.868530402125958 0.964262327880813 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/726 53/18639 0.0188679245283019 0.484406673943552 0.878599848890455 0.964262327880813 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/726 53/18639 0.0188679245283019 0.484406673943552 0.878599848890455 0.964262327880813 GO:0001653 peptide receptor activity 3/726 128/18639 0.0234375 0.601723915289256 0.879977791502229 0.964262327880813 GO:0017069 snRNA binding 1/726 54/18639 0.0185185185185185 0.475436179981634 0.883341940233698 0.964262327880813 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/726 54/18639 0.0185185185185185 0.475436179981634 0.883341940233698 0.964262327880813 GO:0050661 NADP binding 1/726 54/18639 0.0185185185185185 0.475436179981634 0.883341940233698 0.964262327880813 GO:0140463 chromatin-protein adaptor activity 1/726 54/18639 0.0185185185185185 0.475436179981634 0.883341940233698 0.964262327880813 GO:0015081 sodium ion transmembrane transporter activity 4/726 164/18639 0.024390243902439 0.626184237048982 0.886136895948242 0.964262327880813 GO:0016298 lipase activity 3/726 130/18639 0.0230769230769231 0.592466624284806 0.886330066793724 0.964262327880813 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/726 130/18639 0.0230769230769231 0.592466624284806 0.886330066793724 0.964262327880813 GO:0015103 inorganic anion transmembrane transporter activity 4/726 165/18639 0.0242424242424242 0.622389181066867 0.888903159517288 0.964262327880813 GO:0170055 lipid transmembrane transporter activity 1/726 56/18639 0.0178571428571429 0.458456316410862 0.892278363458371 0.964262327880813 GO:0005179 hormone activity 3/726 132/18639 0.0227272727272727 0.583489857250188 0.892380518418882 0.964262327880813 GO:0004896 cytokine receptor activity 2/726 96/18639 0.0208333333333333 0.534865702479339 0.892728045394861 0.964262327880813 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/726 57/18639 0.0175438596491228 0.450413223140496 0.896486828621651 0.964262327880813 GO:0042626 ATPase-coupled transmembrane transporter activity 2/726 98/18639 0.0204081632653061 0.523950075898128 0.899311488559756 0.964262327880813 GO:0017116 single-stranded DNA helicase activity 1/726 58/18639 0.0172413793103448 0.442647477913936 0.900531095246378 0.964262327880813 GO:0015297 antiporter activity 3/726 135/18639 0.0222222222222222 0.570523415977961 0.900915513754141 0.964262327880813 GO:0008168 methyltransferase activity 5/726 204/18639 0.0245098039215686 0.629253767622752 0.903031806679559 0.964262327880813 GO:0008514 organic anion transmembrane transporter activity 7/726 269/18639 0.0260223048327138 0.668085041015085 0.903414953259881 0.964262327880813 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/726 60/18639 0.0166666666666667 0.427892561983471 0.908152375597085 0.964262327880813 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/726 60/18639 0.0166666666666667 0.427892561983471 0.908152375597085 0.964262327880813 GO:0140097 catalytic activity, acting on DNA 9/726 336/18639 0.0267857142857143 0.687684474616293 0.910581026962901 0.964262327880813 GO:0140767 enzyme-substrate adaptor activity 3/726 139/18639 0.0215827338129496 0.554105475949819 0.911345275433017 0.964262327880813 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 6/726 243/18639 0.0246913580246914 0.633914906642179 0.915462061948811 0.964262327880813 GO:0008094 ATP-dependent activity, acting on DNA 5/726 210/18639 0.0238095238095238 0.611275088547816 0.915686780601906 0.964262327880813 GO:0061659 ubiquitin-like protein ligase activity 10/726 372/18639 0.0268817204301075 0.690149293521728 0.918213701774489 0.964262327880813 GO:0004676 3-phosphoinositide-dependent protein kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0004711 ribosomal protein S6 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0035175 histone H3S10 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0035979 histone H2AXS139 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0044022 histone H3S28 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0044023 histone H4S1 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0044024 histone H2AS1 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0044025 histone H2BS14 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0072354 histone H3T3 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0072371 histone H2AS121 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0072518 Rho-dependent protein serine/threonine kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0140823 histone H2BS36 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0140855 histone H3S57 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0140995 histone H2A kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0140997 histone H4 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0140998 histone H2B kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:1990244 histone H2AT120 kinase activity 6/726 245/18639 0.0244897959183673 0.628740091077753 0.919112006215385 0.964262327880813 GO:0005319 lipid transporter activity 4/726 178/18639 0.0224719101123595 0.576933791438388 0.919847719730918 0.964262327880813 GO:0004677 DNA-dependent protein kinase activity 6/726 246/18639 0.024390243902439 0.626184237048982 0.920884870399451 0.964262327880813 GO:0140857 histone H3T45 kinase activity 6/726 246/18639 0.024390243902439 0.626184237048982 0.920884870399451 0.964262327880813 GO:0004536 DNA nuclease activity 1/726 64/18639 0.015625 0.401149276859504 0.921689913301248 0.964262327880813 GO:0004497 monooxygenase activity 2/726 106/18639 0.0188679245283019 0.484406673943552 0.922053125190628 0.964262327880813 GO:0035402 histone H3T11 kinase activity 6/726 247/18639 0.0242914979757085 0.623649078194533 0.922623676829362 0.964262327880813 GO:0035403 histone H3T6 kinase activity 6/726 247/18639 0.0242914979757085 0.623649078194533 0.922623676829362 0.964262327880813 GO:0004679 AMP-activated protein kinase activity 6/726 248/18639 0.0241935483870968 0.621134364169555 0.924328932762965 0.964262327880813 GO:0120013 lipid transfer activity 1/726 65/18639 0.0153846153846154 0.394977749523204 0.92475064670331 0.964262327880813 GO:0016741 transferase activity, transferring one-carbon groups 5/726 215/18639 0.0232558139534884 0.597059388814146 0.925099093927366 0.964262327880813 GO:0004843 cysteine-type deubiquitinase activity 2/726 108/18639 0.0185185185185185 0.475436179981634 0.926931282940228 0.965067884295483 GO:0016500 protein-hormone receptor activity 1/726 67/18639 0.0149253731343284 0.383187368940422 0.930518361253164 0.967696606280402 GO:0140223 general transcription initiation factor activity 1/726 68/18639 0.0147058823529412 0.377552260573651 0.933234475281282 0.96941460317132 GO:0061630 ubiquitin protein ligase activity 9/726 353/18639 0.0254957507082153 0.654566525413808 0.935500943070856 0.970662140247779 GO:0046943 carboxylic acid transmembrane transporter activity 4/726 188/18639 0.0212765957446809 0.546245823808686 0.938142082973039 0.972295150840089 GO:0005342 organic acid transmembrane transporter activity 4/726 189/18639 0.0211640211640212 0.543355634264725 0.939745578565568 0.972850252355946 GO:0101005 deubiquitinase activity 2/726 115/18639 0.0173913043478261 0.446496586417535 0.94182879740118 0.973900152590777 GO:0015294 solute:monoatomic cation symporter activity 2/726 116/18639 0.0172413793103448 0.442647477913936 0.94370544813979 0.974177341255711 GO:0004521 RNA endonuclease activity 1/726 73/18639 0.0136986301369863 0.351692516698743 0.945304819195977 0.974177341255711 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 5/726 229/18639 0.0218340611353712 0.560557941463062 0.946678231644951 0.974177341255711 GO:0003678 DNA helicase activity 1/726 74/18639 0.0135135135135135 0.346939915121733 0.94744360521686 0.974177341255711 GO:0048029 monosaccharide binding 1/726 74/18639 0.0135135135135135 0.346939915121733 0.94744360521686 0.974177341255711 GO:0016755 aminoacyltransferase activity 13/726 496/18639 0.0262096774193548 0.672895561183684 0.952675538252302 0.978452553943458 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/726 122/18639 0.0163934426229508 0.420877929819808 0.953810189976965 0.978514733185828 GO:0015370 solute:sodium symporter activity 1/726 79/18639 0.0126582278481013 0.324981692645674 0.956947953178518 0.98062945483198 GO:0015101 organic cation transmembrane transporter activity 1/726 81/18639 0.0123456790123457 0.31695745332109 0.960250247201045 0.981350571224427 GO:0016874 ligase activity 3/726 167/18639 0.0179640718562874 0.46120156381452 0.960494959125927 0.981350571224427 GO:0019783 ubiquitin-like protein peptidase activity 2/726 127/18639 0.015748031496063 0.404307932582807 0.960883325501854 0.981350571224427 GO:0030165 PDZ domain binding 1/726 83/18639 0.0120481927710843 0.309319924325401 0.963299561818888 0.982716574263166 GO:0004518 nuclease activity 4/726 209/18639 0.0191387559808612 0.491359879789632 0.964808314338301 0.983154781165763 GO:0140030 modification-dependent protein binding 3/726 173/18639 0.0173410404624277 0.445206133855635 0.966975046143727 0.983980911299724 GO:0045182 translation regulator activity 8/726 356/18639 0.0224719101123595 0.576933791438388 0.969609619545391 0.983980911299724 GO:0015291 secondary active transmembrane transporter activity 6/726 287/18639 0.0209059233449477 0.536729346041985 0.969649363798138 0.983980911299724 GO:0004197 cysteine-type endopeptidase activity 1/726 88/18639 0.0113636363636364 0.291744928625094 0.969939471292153 0.983980911299724 GO:0052689 carboxylic ester hydrolase activity 1/726 92/18639 0.0108695652173913 0.279060366510959 0.974376423643845 0.987382560555665 GO:0008234 cysteine-type peptidase activity 3/726 187/18639 0.0160427807486631 0.411875193353074 0.978410379799824 0.990274265196527 GO:0015293 symporter activity 2/726 146/18639 0.0136986301369863 0.351692516698743 0.979404075677355 0.990274265196527 GO:0019787 ubiquitin-like protein transferase activity 11/726 479/18639 0.022964509394572 0.589580565572215 0.981168324442499 0.990424046979553 GO:0004842 ubiquitin-protein transferase activity 10/726 449/18639 0.022271714922049 0.571794069465663 0.982547491416651 0.990424046979553 GO:0015171 amino acid transmembrane transporter activity 1/726 102/18639 0.00980392156862745 0.251701507049101 0.9828137634133 0.990424046979553 GO:0000149 SNARE binding 1/726 106/18639 0.00943396226415094 0.242203336971776 0.985352265136494 0.991884987336294 GO:0004540 RNA nuclease activity 1/726 121/18639 0.00826446280991736 0.212178129909159 0.991958342089367 0.997432725875732 GO:0015631 tubulin binding 7/726 385/18639 0.0181818181818182 0.46679188580015 0.993586165120027 0.997968022518571 GO:0008017 microtubule binding 4/726 276/18639 0.0144927536231884 0.372080488681279 0.994953337138878 0.99824062790035 GO:0019842 vitamin binding 1/726 150/18639 0.00666666666666667 0.171157024793388 0.997480892690542 0.999675570122204 GO:0030371 translation repressor activity 3/726 329/18639 0.00911854103343465 0.234105353060866 0.999801033274263 0.999853240251408 GO:0140098 catalytic activity, acting on RNA 4/726 387/18639 0.0103359173126615 0.265359728361843 0.999853240251408 0.999853240251408