ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 33/573 175/18639 0.188571428571429 6.13400149588631 4.12907479898438e-17 3.53448802793063e-14 GO:0005201 extracellular matrix structural constituent 32/573 168/18639 0.19047619047619 6.19596110695587 9.18359516837414e-17 3.93057873206413e-14 GO:0019838 growth factor binding 20/573 136/18639 0.147058823529412 4.78364644287034 6.55175993738658e-09 1.8694355021343e-06 GO:0001968 fibronectin binding 10/573 30/18639 0.333333333333333 10.8429319371728 1.20313580410316e-08 2.15016775364422e-06 GO:0050840 extracellular matrix binding 14/573 67/18639 0.208955223880597 6.79706181136204 1.25593910843704e-08 2.15016775364422e-06 GO:0002020 protease binding 18/573 136/18639 0.132352941176471 4.30528179858331 1.93889566493233e-07 2.76615781530346e-05 GO:0005539 glycosaminoglycan binding 24/573 242/18639 0.0991735537190083 3.22599627882826 4.88241981949608e-07 5.97050195069807e-05 GO:0008135 translation factor activity, RNA binding 13/573 83/18639 0.156626506024096 5.09487163312938 1.40838166781703e-06 0.000132980742978513 GO:0008201 heparin binding 19/573 172/18639 0.11046511627907 3.59329721173749 1.51837966087906e-06 0.000132980742978513 GO:0180051 translation factor activity 13/573 84/18639 0.154761904761905 5.03421839940165 1.62011798099887e-06 0.000132980742978513 GO:0045296 cadherin binding 28/573 334/18639 0.0838323353293413 2.72696491833088 1.70886468780799e-06 0.000132980742978513 GO:0005178 integrin binding 18/573 161/18639 0.111801242236025 3.63675978016975 2.39960471051114e-06 0.000171171802683128 GO:0003924 GTPase activity 27/573 331/18639 0.081570996978852 2.65340630486705 4.36786862205086e-06 0.000287607349267349 GO:0005518 collagen binding 11/573 72/18639 0.152777777777778 4.96967713787086 1.16280761419097e-05 0.000710973798391051 GO:1901681 sulfur compound binding 23/573 275/18639 0.0836363636363636 2.72059019514517 1.48545220412075e-05 0.00079818384761879 GO:0004857 enzyme inhibitor activity 30/573 416/18639 0.0721153846153846 2.34582662102296 1.50377952399572e-05 0.00079818384761879 GO:0005520 insulin-like growth factor binding 6/573 19/18639 0.315789473684211 10.2722513089005 1.58517820204666e-05 0.00079818384761879 GO:0003779 actin binding 31/573 443/18639 0.0699774266365688 2.27628142247645 1.95800070258214e-05 0.00093113811189462 GO:0003743 translation initiation factor activity 9/573 51/18639 0.176470588235294 5.74037573144441 2.2129167343214e-05 0.000996977223462693 GO:0061134 peptidase regulator activity 20/573 226/18639 0.0884955752212389 2.87865449659454 2.36613274695597e-05 0.00101270481569715 GO:0031994 insulin-like growth factor I binding 5/573 13/18639 0.384615384615385 12.5110753121224 2.82945016878917e-05 0.0011533377830874 GO:0019001 guanyl nucleotide binding 28/573 400/18639 0.07 2.27701570680628 4.88259559192132e-05 0.0018171747072542 GO:0032561 guanyl ribonucleotide binding 28/573 400/18639 0.07 2.27701570680628 4.88259559192132e-05 0.0018171747072542 GO:0019003 GDP binding 10/573 75/18639 0.133333333333333 4.33717277486911 9.58258966019043e-05 0.00341779031213459 GO:0005525 GTP binding 26/573 378/18639 0.0687830687830688 2.23743039973406 0.000119717495877563 0.00409912705884774 GO:0019843 rRNA binding 9/573 65/18639 0.138461538461538 4.50398711236408 0.000158745017080237 0.0052263744084878 GO:0043236 laminin binding 6/573 29/18639 0.206896551724138 6.73009568514172 0.000213609384520991 0.006772208635184 GO:0048407 platelet-derived growth factor binding 4/573 11/18639 0.363636363636364 11.8286530223703 0.000245512240373682 0.00750565991999542 GO:0016504 peptidase activator activity 8/573 57/18639 0.140350877192982 4.56544502617801 0.00033296065486502 0.00982808001946402 GO:0030020 extracellular matrix structural constituent conferring tensile strength 7/573 44/18639 0.159090909090909 5.17503569728701 0.000356796239842945 0.0101805860435187 GO:0140311 protein sequestering activity 6/573 33/18639 0.181818181818182 5.91432651118515 0.000448734895833807 0.0123908732527013 GO:0005080 protein kinase C binding 7/573 52/18639 0.134615384615385 4.37887635924285 0.00100797477534364 0.0269633252404423 GO:0005521 lamin binding 4/573 16/18639 0.25 8.13219895287958 0.0011979248107537 0.0310734435759141 GO:0003925 G protein activity 7/573 54/18639 0.12962962962963 4.21669575334497 0.00126571209406591 0.0318661633094242 GO:0019955 cytokine binding 12/573 144/18639 0.0833333333333333 2.71073298429319 0.00165761518023707 0.0405405312652267 GO:0003746 translation elongation factor activity 4/573 18/18639 0.222222222222222 7.22862129144852 0.00191813716902484 0.0456090393523683 GO:0051015 actin filament binding 15/573 209/18639 0.0717703349282297 2.33460257020466 0.0020970252032769 0.0481428150066399 GO:0045309 protein phosphorylated amino acid binding 7/573 59/18639 0.11864406779661 3.85934865560387 0.00213718104001439 0.0481428150066399 GO:0017022 myosin binding 8/573 76/18639 0.105263157894737 3.42408376963351 0.00228488236079737 0.0501502384831422 GO:0005200 structural constituent of cytoskeleton 10/573 112/18639 0.0892857142857143 2.90435676888556 0.00238155872624873 0.0509653567417229 GO:0042288 MHC class I protein binding 4/573 20/18639 0.2 6.50575916230367 0.00289266967284686 0.0603932985355344 GO:0001784 phosphotyrosine residue binding 6/573 47/18639 0.127659574468085 4.15261223125766 0.00302618884420282 0.061676610729467 GO:0044325 transmembrane transporter binding 11/573 136/18639 0.0808823529411765 2.63100554357869 0.00321531760451852 0.0640072527783222 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/573 22/18639 0.181818181818182 5.91432651118515 0.00416019323389875 0.0782940668267926 GO:0004866 endopeptidase inhibitor activity 12/573 161/18639 0.0745341614906832 2.42450652011317 0.00417080466559933 0.0782940668267926 GO:0033218 amide binding 16/573 247/18639 0.0647773279352227 2.10712847362062 0.0042073914416267 0.0782940668267926 GO:0061135 endopeptidase regulator activity 13/573 184/18639 0.0706521739130435 2.29823013885727 0.00461384608965346 0.0840308989945396 GO:0005212 structural constituent of eye lens 4/573 23/18639 0.173913043478261 5.65718188026406 0.00491533011011493 0.0845313728966313 GO:0016209 antioxidant activity 8/573 86/18639 0.0930232558139535 3.02593449409473 0.00492806913356066 0.0845313728966313 GO:0005516 calmodulin binding 14/573 207/18639 0.0676328502415459 2.20001517565824 0.00493758019256024 0.0845313728966313 GO:0004859 phospholipase inhibitor activity 3/573 12/18639 0.25 8.13219895287958 0.00516738442622273 0.0867310013499344 GO:0005246 calcium channel regulator activity 6/573 53/18639 0.113207547169811 3.68250518620962 0.00554366893097283 0.0912573193252451 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/573 54/18639 0.111111111111111 3.61431064572426 0.00607841353558621 0.0969770277613059 GO:0030414 peptidase inhibitor activity 12/573 169/18639 0.0710059171597633 2.30973698069953 0.00611770969522257 0.0969770277613059 GO:0140313 molecular sequestering activity 6/573 55/18639 0.109090909090909 3.54859590671109 0.00664974495541663 0.10349421239703 GO:0072341 modified amino acid binding 8/573 91/18639 0.0879120879120879 2.85967435705656 0.0069135917591725 0.10567918831878 GO:0015036 disulfide oxidoreductase activity 5/573 40/18639 0.125 4.06609947643979 0.00730196480287708 0.109657576688821 GO:0051219 phosphoprotein binding 8/573 93/18639 0.0860215053763441 2.79817598378652 0.00785765311475595 0.115968121831571 GO:0005161 platelet-derived growth factor receptor binding 3/573 14/18639 0.214285714285714 6.97045624532536 0.0081675964498731 0.118499365442227 GO:0001786 phosphatidylserine binding 6/573 59/18639 0.101694915254237 3.30801313337474 0.00932822188397883 0.133082632211431 GO:0051371 muscle alpha-actinin binding 3/573 15/18639 0.2 6.50575916230367 0.00997932585007633 0.137201062753928 GO:0051019 mitogen-activated protein kinase binding 4/573 28/18639 0.142857142857143 4.6469708302169 0.0100715053060869 0.137201062753928 GO:0019208 phosphatase regulator activity 9/573 117/18639 0.0769230769230769 2.50221506242449 0.0100977417681045 0.137201062753928 GO:0042277 peptide binding 15/573 249/18639 0.0602409638554217 1.95956601274207 0.0103894439821689 0.138958813261509 GO:0030547 signaling receptor inhibitor activity 5/573 44/18639 0.113636363636364 3.69645406949072 0.0109049412772434 0.143609688204928 GO:0048306 calcium-dependent protein binding 7/573 80/18639 0.0875 2.84626963350785 0.0114882119525771 0.148998627748576 GO:0055102 lipase inhibitor activity 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.153387572822767 GO:0008429 phosphatidylethanolamine binding 3/573 17/18639 0.176470588235294 5.74037573144441 0.0142508911741621 0.176793664421489 GO:0048038 quinone binding 3/573 17/18639 0.176470588235294 5.74037573144441 0.0142508911741621 0.176793664421489 GO:0038024 cargo receptor activity 6/573 65/18639 0.0923076923076923 3.00265807490938 0.014670668264609 0.177548413518661 GO:0004860 protein kinase inhibitor activity 7/573 84/18639 0.0833333333333333 2.71073298429319 0.014763404896183 0.177548413518661 GO:0016247 channel regulator activity 11/573 168/18639 0.0654761904761905 2.12986163051608 0.0149339787071771 0.177548413518661 GO:0141108 transporter regulator activity 11/573 170/18639 0.0647058823529412 2.10480443486295 0.0161803128035474 0.18829118856266 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/573 86/18639 0.0813953488372093 2.64769268233289 0.0166287996689892 0.18829118856266 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/573 18/18639 0.166666666666667 5.42146596858639 0.0167174419751895 0.18829118856266 GO:0098641 cadherin binding involved in cell-cell adhesion 3/573 18/18639 0.166666666666667 5.42146596858639 0.0167174419751895 0.18829118856266 GO:0019888 protein phosphatase regulator activity 8/573 107/18639 0.0747663551401869 2.4320594999266 0.0173889458779278 0.19331087885073 GO:0019956 chemokine binding 4/573 33/18639 0.121212121212121 3.9428843407901 0.0178492999680824 0.19588462529075 GO:0015035 protein-disulfide reductase activity 4/573 34/18639 0.117647058823529 3.82691715429627 0.0197505707686056 0.214006184530714 GO:0019210 kinase inhibitor activity 7/573 90/18639 0.0777777777777778 2.53001745200698 0.020848241321489 0.223076182139932 GO:0004864 protein phosphatase inhibitor activity 5/573 53/18639 0.0943396226415094 3.06875432184135 0.0230414915037616 0.243500206508888 GO:0099106 ion channel regulator activity 10/573 160/18639 0.0625 2.0330497382199 0.0262750356163279 0.274285737653375 GO:0004867 serine-type endopeptidase inhibitor activity 7/573 95/18639 0.0736842105263158 2.39685863874346 0.0271016416733025 0.279506087618638 GO:0019212 phosphatase inhibitor activity 5/573 56/18639 0.0892857142857143 2.90435676888556 0.0284793566949728 0.290218206320199 GO:0140517 protein-RNA adaptor activity 3/573 22/18639 0.136363636363636 4.43574488338886 0.0288240234523491 0.290274871473068 GO:0098631 cell adhesion mediator activity 6/573 76/18639 0.0789473684210526 2.56806282722513 0.02937066810587 0.29234060347238 GO:0004601 peroxidase activity 5/573 57/18639 0.087719298245614 2.85340314136126 0.0304574057778184 0.299672866043822 GO:0020037 heme binding 9/573 142/18639 0.0633802816901408 2.0616842415751 0.031455283679674 0.303368243017539 GO:0017134 fibroblast growth factor binding 3/573 23/18639 0.130434782608696 4.24288641019804 0.0324103274536842 0.303368243017539 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/573 58/18639 0.0862068965517241 2.80420653547572 0.0325197148516916 0.303368243017539 GO:0015399 primary active transmembrane transporter activity 10/573 166/18639 0.0602409638554217 1.95956601274207 0.0327029773989015 0.303368243017539 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/573 40/18639 0.1 3.25287958115183 0.0337333886639899 0.303368243017539 GO:0061791 GTPase motor activity 4/573 40/18639 0.1 3.25287958115183 0.0337333886639899 0.303368243017539 GO:0071949 FAD binding 4/573 40/18639 0.1 3.25287958115183 0.0337333886639899 0.303368243017539 GO:1990606 membrane scission GTPase motor activity 4/573 40/18639 0.1 3.25287958115183 0.0337333886639899 0.303368243017539 GO:0046332 SMAD binding 6/573 79/18639 0.0759493670886076 2.47054145403937 0.0346197182514788 0.303368243017539 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/573 59/18639 0.0847457627118644 2.75667761114562 0.034667075311665 0.303368243017539 GO:0005528 FK506 binding 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.303368243017539 GO:0032395 MHC class II receptor activity 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.303368243017539 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.303368243017539 GO:0050431 transforming growth factor beta binding 3/573 24/18639 0.125 4.06609947643979 0.0362179178679365 0.303368243017539 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/573 41/18639 0.0975609756097561 3.17354105478228 0.0365034217649608 0.303368243017539 GO:0042287 MHC protein binding 4/573 41/18639 0.0975609756097561 3.17354105478228 0.0365034217649608 0.303368243017539 GO:0001618 virus receptor activity 6/573 81/18639 0.0740740740740741 2.40954043048284 0.0384346888746913 0.316347054583998 GO:0140272 exogenous protein binding 6/573 82/18639 0.0731707317073171 2.38015579108671 0.0404385729739 0.329670652053889 GO:0008200 ion channel inhibitor activity 4/573 43/18639 0.0930232558139535 3.02593449409473 0.0424253863676431 0.330629498563057 GO:0010854 adenylate cyclase regulator activity 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.330629498563057 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.330629498563057 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.330629498563057 GO:0097493 structural molecule activity conferring elasticity 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.330629498563057 GO:0140031 phosphorylation-dependent protein binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.330629498563057 GO:0005112 Notch binding 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.330629498563057 GO:0008143 poly(A) binding 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.330629498563057 GO:0008157 protein phosphatase 1 binding 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.330629498563057 GO:0050750 low-density lipoprotein particle receptor binding 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.330629498563057 GO:0046906 tetrapyrrole binding 9/573 152/18639 0.0592105263157895 1.92604712041885 0.0453895240349706 0.330629498563057 GO:0003954 NADH dehydrogenase activity 4/573 44/18639 0.0909090909090909 2.95716325559258 0.0455774308766831 0.330629498563057 GO:0016248 channel inhibitor activity 4/573 44/18639 0.0909090909090909 2.95716325559258 0.0455774308766831 0.330629498563057 GO:0043021 ribonucleoprotein complex binding 10/573 177/18639 0.0564971751412429 1.83778507409708 0.0472083435542453 0.332498789621837 GO:0031625 ubiquitin protein ligase binding 15/573 302/18639 0.0496688741721854 1.61566866613502 0.0472485042413298 0.332498789621837 GO:0042605 peptide antigen binding 4/573 45/18639 0.0888888888888889 2.89144851657941 0.0488566039957066 0.332498789621837 GO:0141110 transporter inhibitor activity 4/573 45/18639 0.0888888888888889 2.89144851657941 0.0488566039957066 0.332498789621837 GO:0005044 scavenger receptor activity 3/573 27/18639 0.111111111111111 3.61431064572426 0.048942578846205 0.332498789621837 GO:0015252 proton channel activity 3/573 27/18639 0.111111111111111 3.61431064572426 0.048942578846205 0.332498789621837 GO:0023026 MHC class II protein complex binding 3/573 27/18639 0.111111111111111 3.61431064572426 0.048942578846205 0.332498789621837 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/573 27/18639 0.111111111111111 3.61431064572426 0.048942578846205 0.332498789621837 GO:0005527 macrolide binding 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.342275494064492 GO:0004222 metalloendopeptidase activity 7/573 110/18639 0.0636363636363636 2.0700142789148 0.0531310105643409 0.355313633149029 GO:0051393 alpha-actinin binding 3/573 28/18639 0.107142857142857 3.48522812266268 0.0536071076710192 0.355718481910019 GO:1902936 phosphatidylinositol bisphosphate binding 7/573 111/18639 0.0630630630630631 2.05136550162728 0.0552796466284691 0.363995211645919 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 5/573 68/18639 0.0735294117647059 2.39182322143517 0.0579062486278368 0.364859309013141 GO:1990841 promoter-specific chromatin binding 5/573 68/18639 0.0735294117647059 2.39182322143517 0.0579062486278368 0.364859309013141 GO:0008237 metallopeptidase activity 10/573 184/18639 0.0543478260869565 1.76786933758252 0.0584043994081863 0.364859309013141 GO:0004629 phospholipase C activity 3/573 29/18639 0.103448275862069 3.36504784257086 0.0584765963662847 0.364859309013141 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.364859309013141 GO:0019855 calcium channel inhibitor activity 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.364859309013141 GO:0045159 myosin II binding 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.364859309013141 GO:0140333 glycerophospholipid flippase activity 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.364859309013141 GO:1901981 phosphatidylinositol phosphate binding 10/573 185/18639 0.0540540540540541 1.7583132871091 0.0601338512906888 0.370320695718199 GO:0008083 growth factor activity 9/573 162/18639 0.0555555555555556 1.80715532286213 0.0629368021147823 0.38306960883905 GO:0001222 transcription corepressor binding 4/573 49/18639 0.0816326530612245 2.65541190298109 0.0632336283104313 0.38306960883905 GO:0016769 transferase activity, transferring nitrogenous groups 3/573 30/18639 0.1 3.25287958115183 0.0635465939896554 0.38306960883905 GO:0097110 scaffold protein binding 5/573 70/18639 0.0714285714285714 2.32348541510845 0.0640370657534881 0.383326771223677 GO:0009055 electron transfer activity 7/573 116/18639 0.0603448275862069 1.962944574833 0.0668266881164958 0.391680986332882 GO:0008191 metalloendopeptidase inhibitor activity 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.391680986332882 GO:0008559 ABC-type xenobiotic transporter activity 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.391680986332882 GO:0032036 myosin heavy chain binding 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.391680986332882 GO:0070325 lipoprotein particle receptor binding 3/573 31/18639 0.0967741935483871 3.14794798175984 0.0688123459949054 0.397995730889453 GO:0022853 active monoatomic ion transmembrane transporter activity 7/573 118/18639 0.0593220338983051 1.92967432780193 0.0718225976861667 0.412618413552743 GO:0044389 ubiquitin-like protein ligase binding 15/573 322/18639 0.046583850931677 1.51531657507073 0.0733461318500018 0.415517106971805 GO:0031369 translation initiation factor binding 3/573 32/18639 0.09375 3.04957460732984 0.0742688286993998 0.415517106971805 GO:0051059 NF-kappaB binding 3/573 32/18639 0.09375 3.04957460732984 0.0742688286993998 0.415517106971805 GO:0070717 poly-purine tract binding 3/573 32/18639 0.09375 3.04957460732984 0.0742688286993998 0.415517106971805 GO:0004129 cytochrome-c oxidase activity 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.420134972212742 GO:0120283 protein serine/threonine kinase binding 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.420134972212742 GO:0019903 protein phosphatase binding 8/573 144/18639 0.0555555555555556 1.80715532286213 0.0767240003617157 0.420998360959158 GO:0030695 GTPase regulator activity 21/573 489/18639 0.0429447852760736 1.3969421514149 0.0783272304543225 0.427058020821019 GO:0060589 nucleoside-triphosphatase regulator activity 21/573 490/18639 0.0428571428571429 1.39409124906507 0.0796016185205726 0.429190143173347 GO:0051082 unfolded protein binding 7/573 121/18639 0.0578512396694215 1.88183116264982 0.0797210663137408 0.429190143173347 GO:0015485 cholesterol binding 4/573 54/18639 0.0740740740740741 2.40954043048284 0.083965717531651 0.442091706403649 GO:0000062 fatty-acyl-CoA binding 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.442091706403649 GO:0004708 MAP kinase kinase activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.442091706403649 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.442091706403649 GO:0022841 potassium ion leak channel activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.442091706403649 GO:0140327 flippase activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.442091706403649 GO:0030332 cyclin binding 3/573 34/18639 0.0882352941176471 2.87018786572221 0.0857327374567824 0.442091706403649 GO:0098632 cell-cell adhesion mediator activity 4/573 55/18639 0.0727272727272727 2.36573060447406 0.0884661906624309 0.453023297116179 GO:0005543 phospholipid binding 21/573 497/18639 0.0422535211267606 1.37445616105007 0.0889111143872874 0.453023297116179 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.468535870573538 GO:0016018 cyclosporin A binding 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.468535870573538 GO:0032977 membrane insertase activity 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.468535870573538 GO:0070492 oligosaccharide binding 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.468535870573538 GO:1901567 fatty acid derivative binding 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.468535870573538 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/573 36/18639 0.0833333333333333 2.71073298429319 0.0978939241962689 0.476120449500035 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/573 36/18639 0.0833333333333333 2.71073298429319 0.0978939241962689 0.476120449500035 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/573 36/18639 0.0833333333333333 2.71073298429319 0.0978939241962689 0.476120449500035 GO:0000287 magnesium ion binding 11/573 230/18639 0.0478260869565217 1.55572501707262 0.0989311407742523 0.478446646908249 GO:0023023 MHC protein complex binding 3/573 37/18639 0.0810810810810811 2.63746993066365 0.104221432745216 0.49120894241225 GO:0042805 actinin binding 3/573 37/18639 0.0810810810810811 2.63746993066365 0.104221432745216 0.49120894241225 GO:0043394 proteoglycan binding 3/573 37/18639 0.0810810810810811 2.63746993066365 0.104221432745216 0.49120894241225 GO:0035615 clathrin adaptor activity 2/573 18/18639 0.111111111111111 3.61431064572426 0.104439284484848 0.49120894241225 GO:0070064 proline-rich region binding 2/573 18/18639 0.111111111111111 3.61431064572426 0.104439284484848 0.49120894241225 GO:0051020 GTPase binding 14/573 315/18639 0.0444444444444444 1.4457242582897 0.108302350160981 0.506594599660107 GO:0001540 amyloid-beta binding 5/573 83/18639 0.0602409638554217 1.95956601274207 0.112228005094013 0.518324028437348 GO:0008574 plus-end-directed microtubule motor activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.518324028437348 GO:0022840 leak channel activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.518324028437348 GO:0022842 narrow pore channel activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.518324028437348 GO:0097001 ceramide binding 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.518324028437348 GO:0120227 acyl-CoA binding 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.518324028437348 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/573 39/18639 0.0769230769230769 2.50221506242449 0.117340155719405 0.525192914646145 GO:0015026 coreceptor activity 4/573 61/18639 0.0655737704918033 2.13303579091923 0.117787649872147 0.525192914646145 GO:0015078 proton transmembrane transporter activity 9/573 185/18639 0.0486486486486487 1.58248195839819 0.117800279920631 0.525192914646145 GO:0004175 endopeptidase activity 17/573 405/18639 0.0419753086419753 1.36540624394028 0.121670670501147 0.539637792481772 GO:0010851 cyclase regulator activity 2/573 20/18639 0.1 3.25287958115183 0.124678739955472 0.541652579886584 GO:0016408 C-acyltransferase activity 2/573 20/18639 0.1 3.25287958115183 0.124678739955472 0.541652579886584 GO:0016505 peptidase activator activity involved in apoptotic process 2/573 20/18639 0.1 3.25287958115183 0.124678739955472 0.541652579886584 GO:0043024 ribosomal small subunit binding 2/573 20/18639 0.1 3.25287958115183 0.124678739955472 0.541652579886584 GO:0050660 flavin adenine dinucleotide binding 5/573 86/18639 0.0581395348837209 1.8912090588092 0.125288797684046 0.541652579886584 GO:0140597 protein carrier chaperone 9/573 188/18639 0.0478723404255319 1.55722958672162 0.126438695390574 0.543877001278049 GO:0008081 phosphoric diester hydrolase activity 5/573 87/18639 0.0574712643678161 1.86947102365048 0.129791794511341 0.555508880508539 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/573 41/18639 0.0731707317073171 2.38015579108671 0.131036108647398 0.555909231911132 GO:0043022 ribosome binding 6/573 112/18639 0.0535714285714286 1.74261406133134 0.131184187904263 0.555909231911132 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/573 88/18639 0.0568181818181818 1.84822703474536 0.134367292401972 0.558768417127374 GO:0001846 opsonin binding 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.558768417127374 GO:0036122 BMP binding 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.558768417127374 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.558768417127374 GO:0140312 cargo adaptor activity 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.558768417127374 GO:0016859 cis-trans isomerase activity 3/573 42/18639 0.0714285714285714 2.32348541510845 0.138084986025101 0.56286070494041 GO:0035198 miRNA binding 3/573 42/18639 0.0714285714285714 2.32348541510845 0.138084986025101 0.56286070494041 GO:0042056 chemoattractant activity 3/573 42/18639 0.0714285714285714 2.32348541510845 0.138084986025101 0.56286070494041 GO:0017124 SH3 domain binding 6/573 115/18639 0.0521739130434783 1.69715456407922 0.143373990200149 0.58164993180724 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/573 43/18639 0.0697674418604651 2.26945087057105 0.14525945599941 0.583010430712065 GO:0008375 acetylglucosaminyltransferase activity 3/573 43/18639 0.0697674418604651 2.26945087057105 0.14525945599941 0.583010430712065 GO:0008093 cytoskeletal anchor activity 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.583010430712065 GO:0140104 molecular carrier activity 11/573 249/18639 0.0441767068273092 1.43701507601085 0.146619215017732 0.583749060721761 GO:0016790 thiolester hydrolase activity 3/573 44/18639 0.0681818181818182 2.21787244169443 0.152553262715707 0.601776925735693 GO:0019205 nucleobase-containing compound kinase activity 3/573 44/18639 0.0681818181818182 2.21787244169443 0.152553262715707 0.601776925735693 GO:0043178 alcohol binding 5/573 92/18639 0.0543478260869565 1.76786933758252 0.153365989896444 0.602207740143835 GO:0032934 sterol binding 4/573 68/18639 0.0588235294117647 1.91345857714814 0.156521599200545 0.603623092956687 GO:0031681 G-protein beta-subunit binding 2/573 23/18639 0.0869565217391304 2.82859094013203 0.156547110556524 0.603623092956687 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/573 23/18639 0.0869565217391304 2.82859094013203 0.156547110556524 0.603623092956687 GO:0140103 catalytic activity, acting on a glycoprotein 2/573 23/18639 0.0869565217391304 2.82859094013203 0.156547110556524 0.603623092956687 GO:0008009 chemokine activity 3/573 45/18639 0.0666666666666667 2.16858638743456 0.159960166909993 0.61127635212033 GO:0140303 intramembrane lipid transporter activity 3/573 45/18639 0.0666666666666667 2.16858638743456 0.159960166909993 0.61127635212033 GO:0035091 phosphatidylinositol binding 12/573 284/18639 0.0422535211267606 1.37445616105007 0.166817640092422 0.61531384391013 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/573 46/18639 0.0652173913043478 2.12144320509902 0.167473958372982 0.61531384391013 GO:0030291 protein serine/threonine kinase inhibitor activity 3/573 46/18639 0.0652173913043478 2.12144320509902 0.167473958372982 0.61531384391013 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.61531384391013 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.61531384391013 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.61531384391013 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.61531384391013 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.61531384391013 GO:0060229 lipase activator activity 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.61531384391013 GO:0005085 guanyl-nucleotide exchange factor activity 10/573 230/18639 0.0434782608695652 1.41429547006601 0.172335415692315 0.630423571934282 GO:0004896 cytokine receptor activity 5/573 96/18639 0.0520833333333333 1.69420811518325 0.173407080651881 0.630738522244301 GO:0043495 protein-membrane adaptor activity 3/573 47/18639 0.0638297872340425 2.07630611562883 0.175088467404635 0.630738522244301 GO:0140359 ABC-type transporter activity 3/573 47/18639 0.0638297872340425 2.07630611562883 0.175088467404635 0.630738522244301 GO:0019207 kinase regulator activity 12/573 287/18639 0.0418118466898955 1.36008902347812 0.175368888194093 0.630738522244301 GO:0001848 complement binding 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.636830546950103 GO:0047617 fatty acyl-CoA hydrolase activity 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.636830546950103 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/573 48/18639 0.0625 2.0330497382199 0.182797575316182 0.646589770539884 GO:0140693 molecular condensate scaffold activity 3/573 48/18639 0.0625 2.0330497382199 0.182797575316182 0.646589770539884 GO:0042626 ATPase-coupled transmembrane transporter activity 5/573 98/18639 0.0510204081632653 1.65963243936318 0.183786662613443 0.647413099576573 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.649610110454909 GO:0004435 phosphatidylinositol phospholipase C activity 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.649610110454909 GO:0016289 acyl-CoA hydrolase activity 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.649610110454909 GO:0019865 immunoglobulin binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.649610110454909 GO:0030247 polysaccharide binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.649610110454909 GO:0034237 protein kinase A regulatory subunit binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.649610110454909 GO:0043548 phosphatidylinositol 3-kinase binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.649610110454909 GO:0003774 cytoskeletal motor activity 7/573 153/18639 0.0457516339869281 1.48824556000411 0.192334717708612 0.655930352026184 GO:0003725 double-stranded RNA binding 4/573 75/18639 0.0533333333333333 1.73486910994764 0.199257299792466 0.674678988327205 GO:0008266 poly(U) RNA binding 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.674678988327205 GO:0008395 steroid hydroxylase activity 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.674678988327205 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.674678988327205 GO:0140375 immune receptor activity 7/573 156/18639 0.0448717948717949 1.45962545308095 0.205214116421444 0.686184701784203 GO:0005048 signal sequence binding 3/573 51/18639 0.0588235294117647 1.91345857714814 0.20643226641528 0.687572062457118 GO:0003724 RNA helicase activity 4/573 77/18639 0.051948051948052 1.68980757462433 0.212064731863282 0.696350222269888 GO:0005242 inward rectifier potassium channel activity 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.696350222269888 GO:0046625 sphingolipid binding 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.696350222269888 GO:0097718 disordered domain specific binding 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.696350222269888 GO:0005096 GTPase activator activity 11/573 271/18639 0.040590405904059 1.32035702555978 0.214119955179795 0.699567487152307 GO:0016887 ATP hydrolysis activity 16/573 417/18639 0.0383693045563549 1.24810727334363 0.215517058344894 0.701454760240415 GO:0005544 calcium-dependent phospholipid binding 3/573 53/18639 0.0566037735849057 1.84125259310481 0.222552655475535 0.721610125329764 GO:0003785 actin monomer binding 2/573 29/18639 0.0689655172413793 2.24336522838057 0.223717674774217 0.722650300402754 GO:0008186 ATP-dependent activity, acting on RNA 4/573 79/18639 0.0506329113924051 1.64702763602624 0.22509459150042 0.724364550091578 GO:0008013 beta-catenin binding 5/573 106/18639 0.0471698113207547 1.53437716092068 0.227381826602417 0.725111179349038 GO:0051087 protein-folding chaperone binding 6/573 134/18639 0.0447761194029851 1.45651324529187 0.231027893064846 0.725111179349038 GO:0008017 microtubule binding 11/573 276/18639 0.0398550724637681 1.29643751422718 0.231044171247796 0.725111179349038 GO:0019902 phosphatase binding 8/573 190/18639 0.0421052631578947 1.3696335078534 0.23115777173977 0.725111179349038 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.725111179349038 GO:0008187 poly-pyrimidine tract binding 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.725111179349038 GO:0048019 receptor antagonist activity 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.725111179349038 GO:0004620 phospholipase activity 5/573 109/18639 0.0458715596330275 1.49214659685864 0.244460972407298 0.725111179349038 GO:0017147 Wnt-protein binding 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.725111179349038 GO:0046982 protein heterodimerization activity 14/573 369/18639 0.037940379403794 1.23415485463755 0.247253152723967 0.725111179349038 GO:0008236 serine-type peptidase activity 8/573 194/18639 0.0412371134020619 1.3413936417121 0.248055595867189 0.725111179349038 GO:0031267 small GTPase binding 11/573 283/18639 0.03886925795053 1.26437015521803 0.255567689736142 0.725111179349038 GO:0070851 growth factor receptor binding 6/573 139/18639 0.0431654676258993 1.40412068251158 0.256498682188948 0.725111179349038 GO:0042910 xenobiotic transmembrane transporter activity 2/573 32/18639 0.0625 2.0330497382199 0.258121398069562 0.725111179349038 GO:0019887 protein kinase regulator activity 10/573 255/18639 0.0392156862745098 1.27563905143209 0.260398343806145 0.725111179349038 GO:0004713 protein tyrosine kinase activity 6/573 140/18639 0.0428571428571429 1.39409124906507 0.261683188544012 0.725111179349038 GO:0061980 regulatory RNA binding 3/573 58/18639 0.0517241379310345 1.68252392128543 0.263798800769804 0.725111179349038 GO:0003713 transcription coactivator activity 10/573 256/18639 0.0390625 1.27065608638743 0.264204624115604 0.725111179349038 GO:0017171 serine hydrolase activity 8/573 198/18639 0.0404040404040404 1.31429478026337 0.265338977255893 0.725111179349038 GO:0003796 lysozyme activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0004382 GDP phosphatase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0005131 growth hormone receptor binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0005522 profilin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0030957 Tat protein binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0031434 mitogen-activated protein kinase kinase binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0031720 haptoglobin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0031996 thioesterase binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0035256 G protein-coupled glutamate receptor binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0043121 neurotrophin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0043208 glycosphingolipid binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0043295 glutathione binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0050815 phosphoserine residue binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0051880 G-quadruplex DNA binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0070097 delta-catenin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0070513 death domain binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.725111179349038 GO:0031593 polyubiquitin modification-dependent protein binding 3/573 59/18639 0.0508474576271186 1.65400656668737 0.272167310473285 0.725111179349038 GO:0001221 transcription coregulator binding 5/573 115/18639 0.0434782608695652 1.41429547006601 0.279541937427832 0.725111179349038 GO:0035401 histone H3Y41 kinase activity 5/573 115/18639 0.0434782608695652 1.41429547006601 0.279541937427832 0.725111179349038 GO:0140801 histone H2AXY142 kinase activity 5/573 115/18639 0.0434782608695652 1.41429547006601 0.279541937427832 0.725111179349038 GO:0019825 oxygen binding 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.725111179349038 GO:0003953 NAD+ nucleosidase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0008199 ferric iron binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0008432 JUN kinase binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0008503 benzodiazepine receptor activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0015217 ADP transmembrane transporter activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0019107 myristoyltransferase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0019206 nucleoside kinase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0019215 intermediate filament binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0032794 GTPase activating protein binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0034713 type I transforming growth factor beta receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0042608 T cell receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0050786 RAGE receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0050998 nitric-oxide synthase binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0070697 activin receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0070990 snRNP binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:1900750 oligopeptide binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:1990948 ubiquitin ligase inhibitor activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.725111179349038 GO:0043015 gamma-tubulin binding 2/573 35/18639 0.0571428571428571 1.85878833208676 0.292589478400696 0.725111179349038 GO:0003727 single-stranded RNA binding 4/573 89/18639 0.0449438202247191 1.46196835107948 0.292770366337099 0.725111179349038 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/573 89/18639 0.0449438202247191 1.46196835107948 0.292770366337099 0.725111179349038 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/573 89/18639 0.0449438202247191 1.46196835107948 0.292770366337099 0.725111179349038 GO:0005125 cytokine activity 9/573 234/18639 0.0384615384615385 1.25110753121224 0.294053364528199 0.725111179349038 GO:0015631 tubulin binding 14/573 385/18639 0.0363636363636364 1.18286530223703 0.298004214003162 0.725111179349038 GO:0004252 serine-type endopeptidase activity 7/573 176/18639 0.0397727272727273 1.29375892432175 0.298052710931942 0.725111179349038 GO:0140793 histone H2AXY142 phosphatase activity 4/573 90/18639 0.0444444444444444 1.4457242582897 0.299702466662514 0.725111179349038 GO:0004033 aldo-keto reductase (NADPH) activity 2/573 36/18639 0.0555555555555556 1.80715532286213 0.30404215805978 0.725111179349038 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/573 36/18639 0.0555555555555556 1.80715532286213 0.30404215805978 0.725111179349038 GO:0005319 lipid transporter activity 7/573 178/18639 0.0393258426966292 1.27922230719454 0.307838755080204 0.725111179349038 GO:0003995 acyl-CoA dehydrogenase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0004032 aldose reductase (NADPH) activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0005049 nuclear export signal receptor activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0005095 GTPase inhibitor activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0005165 neurotrophin receptor binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0010853 cyclase activator activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0016208 AMP binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0016801 hydrolase activity, acting on ether bonds 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0016803 ether hydrolase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0031543 peptidyl-proline dioxygenase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0035259 nuclear glucocorticoid receptor binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0045295 gamma-catenin binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0070008 serine-type exopeptidase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0097371 MDM2/MDM4 family protein binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.725111179349038 GO:0000510 H3-H4 histone complex chaperone activity 6/573 151/18639 0.0397350993377483 1.29253493290801 0.320237094335658 0.734914082443226 GO:0140584 chromatin extrusion motor activity 6/573 151/18639 0.0397350993377483 1.29253493290801 0.320237094335658 0.734914082443226 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 6/573 151/18639 0.0397350993377483 1.29253493290801 0.320237094335658 0.734914082443226 GO:0140849 ATP-dependent H2AZ histone chaperone activity 6/573 151/18639 0.0397350993377483 1.29253493290801 0.320237094335658 0.734914082443226 GO:0160215 deacylase activity 3/573 65/18639 0.0461538461538462 1.50132903745469 0.322798927168691 0.738812517797859 GO:0015616 DNA translocase activity 6/573 152/18639 0.0394736842105263 1.28403141361257 0.325666727956087 0.740070756194629 GO:0140674 ATP-dependent histone chaperone activity 6/573 152/18639 0.0394736842105263 1.28403141361257 0.325666727956087 0.740070756194629 GO:0005109 frizzled binding 2/573 38/18639 0.0526315789473684 1.71204188481675 0.326835759549489 0.740070756194629 GO:0061775 cohesin loader activity 6/573 153/18639 0.0392156862745098 1.27563905143209 0.331108850823331 0.740070756194629 GO:0004465 lipoprotein lipase activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0005035 death receptor activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0005542 folic acid binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0030955 potassium ion binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0031432 titin binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0051011 microtubule minus-end binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.740070756194629 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/573 39/18639 0.0512820512820513 1.66814337494966 0.338159846243007 0.744695974358087 GO:0005126 cytokine receptor binding 10/573 275/18639 0.0363636363636364 1.18286530223703 0.3393760477071 0.744695974358087 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/573 67/18639 0.0447761194029851 1.45651324529187 0.339728362978656 0.744695974358087 GO:0005548 phospholipid transporter activity 3/573 68/18639 0.0441176470588235 1.4350939328611 0.348184059768414 0.744695974358087 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/573 40/18639 0.05 1.62643979057592 0.349425149583273 0.744695974358087 GO:0042826 histone deacetylase binding 5/573 127/18639 0.0393700787401575 1.28066125242198 0.352063735441408 0.744695974358087 GO:0004705 JUN kinase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0005344 oxygen carrier activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0005347 ATP transmembrane transporter activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0005545 1-phosphatidylinositol binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0008331 high voltage-gated calcium channel activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0008474 palmitoyl-(protein) hydrolase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0031404 chloride ion binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0034236 protein kinase A catalytic subunit binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0042043 neurexin family protein binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0044548 S100 protein binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0061783 peptidoglycan muralytic activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0098599 palmitoyl hydrolase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.744695974358087 GO:0004725 protein tyrosine phosphatase activity 4/573 98/18639 0.0408163265306122 1.32770595149054 0.355632217302698 0.744695974358087 GO:0002039 p53 binding 3/573 69/18639 0.0434782608695652 1.41429547006601 0.356628594386617 0.744695974358087 GO:0140658 ATP-dependent chromatin remodeler activity 6/573 158/18639 0.0379746835443038 1.23527072701968 0.358465359468245 0.744695974358087 GO:0001727 lipid kinase activity 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.744695974358087 GO:0017080 sodium channel regulator activity 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.744695974358087 GO:0042169 SH2 domain binding 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.744695974358087 GO:0003689 DNA clamp loader activity 6/573 160/18639 0.0375 1.21982984293194 0.36945434252228 0.744695974358087 GO:0016298 lipase activity 5/573 130/18639 0.0384615384615385 1.25110753121224 0.370419896908121 0.744695974358087 GO:0048487 beta-tubulin binding 2/573 42/18639 0.0476190476190476 1.54899027673897 0.371751567657729 0.744695974358087 GO:0004559 alpha-mannosidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0005041 low-density lipoprotein particle receptor activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0008242 omega peptidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0030553 cGMP binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0031005 filamin binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0031386 protein tag activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0034483 heparan sulfate sulfotransferase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0042809 nuclear vitamin D receptor binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0047372 monoacylglycerol lipase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0048531 beta-1,3-galactosyltransferase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0050780 dopamine receptor binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0141047 molecular tag activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0141050 histone H3K deacetylase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0141051 histone H4K deacetylase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.744695974358087 GO:0042379 chemokine receptor binding 3/573 72/18639 0.0416666666666667 1.3553664921466 0.381858840301409 0.750695017169585 GO:0005245 voltage-gated calcium channel activity 2/573 43/18639 0.0465116279069767 1.51296724704736 0.382799963348378 0.750695017169585 GO:0140713 histone chaperone activity 6/573 164/18639 0.0365853658536585 1.19007789554335 0.391462089731977 0.750695017169585 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0004707 MAP kinase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0005024 transforming growth factor beta receptor activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0008142 oxysterol binding 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0008296 3'-5'-DNA exonuclease activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0015562 efflux transmembrane transporter activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0015923 mannosidase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0016722 oxidoreductase activity, acting on metal ions 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0017070 U6 snRNA binding 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0034450 ubiquitin-ubiquitin ligase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0070411 I-SMAD binding 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0140328 floppase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.750695017169585 GO:0001223 transcription coactivator binding 2/573 44/18639 0.0454545454545455 1.47858162779629 0.393764091949934 0.750695017169585 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/573 45/18639 0.0444444444444444 1.4457242582897 0.404638693114583 0.761730943727098 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0004550 nucleoside diphosphate kinase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0005092 GDP-dissociation inhibitor activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0016805 dipeptidase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0017110 nucleoside diphosphate phosphatase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0019198 transmembrane receptor protein phosphatase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0030169 low-density lipoprotein particle binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0031489 myosin V binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0045236 CXCR chemokine receptor binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0046965 nuclear retinoid X receptor binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0070402 NADPH binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.761730943727098 GO:0004180 carboxypeptidase activity 2/573 46/18639 0.0434782608695652 1.41429547006601 0.41541890833011 0.764728140925966 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/573 46/18639 0.0434782608695652 1.41429547006601 0.41541890833011 0.764728140925966 GO:0005496 steroid binding 4/573 108/18639 0.037037037037037 1.20477021524142 0.425387964973907 0.773463378336951 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0004970 glutamate-gated receptor activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0008525 phosphatidylcholine transporter activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0017075 syntaxin-1 binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0022851 GABA-gated chloride ion channel activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0030228 lipoprotein particle receptor activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:1990381 ubiquitin-specific protease binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.773463378336951 GO:0003823 antigen binding 6/573 174/18639 0.0344827586206897 1.12168261419029 0.446258352543563 0.781999949240899 GO:0016763 pentosyltransferase activity 2/573 49/18639 0.0408163265306122 1.32770595149054 0.447150273585439 0.781999949240899 GO:0035254 glutamate receptor binding 2/573 49/18639 0.0408163265306122 1.32770595149054 0.447150273585439 0.781999949240899 GO:0003756 protein disulfide isomerase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0004890 GABA-A receptor activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0015245 fatty acid transmembrane transporter activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0030506 ankyrin binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0031420 alkali metal ion binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0046624 sphingolipid transporter activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0050145 nucleoside monophosphate kinase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0070003 threonine-type peptidase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0140036 ubiquitin-modified protein reader activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.781999949240899 GO:0022843 voltage-gated monoatomic cation channel activity 5/573 143/18639 0.034965034965035 1.13737048292022 0.449523903042333 0.783691366607407 GO:0004721 phosphoprotein phosphatase activity 6/573 175/18639 0.0342857142857143 1.11527299925206 0.451692902626727 0.785872204570077 GO:0015605 organophosphate ester transmembrane transporter activity 2/573 50/18639 0.04 1.30115183246073 0.457511725615805 0.794381414050973 GO:0000339 RNA cap binding 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.795460473806202 GO:0001614 purinergic nucleotide receptor activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.795460473806202 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.795460473806202 GO:0016004 phospholipase activator activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.795460473806202 GO:0016502 nucleotide receptor activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.795460473806202 GO:0030742 GTP-dependent protein binding 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.795460473806202 GO:0140939 histone H4 methyltransferase activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.795460473806202 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/573 52/18639 0.0384615384615385 1.25110753121224 0.477891864604672 0.808566697191203 GO:0016853 isomerase activity 6/573 180/18639 0.0333333333333333 1.08429319371728 0.478668838712432 0.808566697191203 GO:0051117 ATPase binding 3/573 84/18639 0.0357142857142857 1.16174270755423 0.479734196144841 0.808566697191203 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.808566697191203 GO:0005123 death receptor binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.808566697191203 GO:0035613 RNA stem-loop binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.808566697191203 GO:0061891 calcium ion sensor activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.808566697191203 GO:0070182 DNA polymerase binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.808566697191203 GO:0072542 protein phosphatase activator activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.808566697191203 GO:1990782 protein tyrosine kinase binding 4/573 117/18639 0.0341880341880342 1.11209558329977 0.48647129450801 0.808566697191203 GO:0008146 sulfotransferase activity 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.808566697191203 GO:0016860 intramolecular oxidoreductase activity 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.808566697191203 GO:0051018 protein kinase A binding 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.808566697191203 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.808566697191203 GO:0004407 histone deacetylase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0008970 phospholipase A1 activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0031683 G-protein beta/gamma-subunit complex binding 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0033558 protein lysine deacetylase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0061133 endopeptidase activator activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0070034 telomerase RNA binding 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0140035 ubiquitin-like protein reader activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0140784 metal ion sensor activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.808566697191203 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/573 54/18639 0.037037037037037 1.20477021524142 0.497797487639911 0.808566697191203 GO:0050661 NADP binding 2/573 54/18639 0.037037037037037 1.20477021524142 0.497797487639911 0.808566697191203 GO:0051287 NAD binding 2/573 54/18639 0.037037037037037 1.20477021524142 0.497797487639911 0.808566697191203 GO:0140463 chromatin-protein adaptor activity 2/573 54/18639 0.037037037037037 1.20477021524142 0.497797487639911 0.808566697191203 GO:0008374 O-acyltransferase activity 2/573 55/18639 0.0363636363636364 1.18286530223703 0.507566792700141 0.818569815653676 GO:0000295 adenine nucleotide transmembrane transporter activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0016493 C-C chemokine receptor activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0016917 GABA receptor activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0042171 lysophosphatidic acid acyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0043274 phospholipase binding 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0071617 lysophospholipid acyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0099186 structural constituent of postsynapse 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.818569815653676 GO:0005506 iron ion binding 5/573 154/18639 0.0324675324675325 1.05612973414021 0.51436749856568 0.819922865497621 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/573 122/18639 0.0327868852459016 1.06651789545962 0.519260495968842 0.826183986151168 GO:0004622 lysophospholipase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0004806 triacylglycerol lipase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0005540 hyaluronic acid binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0019957 C-C chemokine binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0030552 cAMP binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0035035 histone acetyltransferase binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0048027 mRNA 5'-UTR binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.827099377523317 GO:0005267 potassium channel activity 4/573 124/18639 0.032258064516129 1.04931599391995 0.532098792307362 0.832681108254299 GO:0005251 delayed rectifier potassium channel activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0008139 nuclear localization sequence binding 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0008483 transaminase activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0015271 outward rectifier potassium channel activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0019211 phosphatase activator activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0042974 nuclear retinoic acid receptor binding 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0120020 cholesterol transfer activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.834612348015981 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/573 60/18639 0.0333333333333333 1.08429319371728 0.554512909401484 0.836748933237631 GO:0001637 G protein-coupled chemoattractant receptor activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0004529 DNA exonuclease activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0004950 chemokine receptor activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0005160 transforming growth factor beta receptor binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0008066 glutamate receptor activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0008198 ferrous iron binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0015216 purine nucleotide transmembrane transporter activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0030507 spectrin binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0050681 nuclear androgen receptor binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0052742 phosphatidylinositol kinase activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0070412 R-SMAD binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.836748933237631 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/573 128/18639 0.03125 1.01652486910995 0.557253443790027 0.836857803305725 GO:0042578 phosphoric ester hydrolase activity 11/573 363/18639 0.0303030303030303 0.985721085197525 0.562449673284013 0.842495729992447 GO:0019905 syntaxin binding 2/573 61/18639 0.0327868852459016 1.06651789545962 0.56351391767942 0.842495729992447 GO:0001664 G protein-coupled receptor binding 9/573 297/18639 0.0303030303030303 0.985721085197525 0.564856511820595 0.842495729992447 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/573 130/18639 0.0307692307692308 1.00088602496979 0.569555239056453 0.842495729992447 GO:0004364 glutathione transferase activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.842495729992447 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.842495729992447 GO:0005104 fibroblast growth factor receptor binding 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.842495729992447 GO:0008320 protein transmembrane transporter activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.842495729992447 GO:0035255 ionotropic glutamate receptor binding 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.842495729992447 GO:0005507 copper ion binding 2/573 63/18639 0.0317460317460317 1.03266018449265 0.581121756507149 0.848398441695489 GO:0022824 transmitter-gated monoatomic ion channel activity 2/573 63/18639 0.0317460317460317 1.03266018449265 0.581121756507149 0.848398441695489 GO:0022835 transmitter-gated channel activity 2/573 63/18639 0.0317460317460317 1.03266018449265 0.581121756507149 0.848398441695489 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/573 132/18639 0.0303030303030303 0.985721085197525 0.581664779224853 0.848398441695489 GO:0046875 ephrin receptor binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.848398441695489 GO:0046966 nuclear thyroid hormone receptor binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.848398441695489 GO:0050698 proteoglycan sulfotransferase activity 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.848398441695489 GO:0051537 2 iron, 2 sulfur cluster binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.848398441695489 GO:0005249 voltage-gated potassium channel activity 3/573 98/18639 0.0306122448979592 0.995779463617908 0.583769488503087 0.848398441695489 GO:0008170 N-methyltransferase activity 3/573 98/18639 0.0306122448979592 0.995779463617908 0.583769488503087 0.848398441695489 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.857357264534138 GO:0035250 UDP-galactosyltransferase activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.857357264534138 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.857357264534138 GO:0051861 glycolipid binding 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.857357264534138 GO:0097472 cyclin-dependent protein kinase activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.857357264534138 GO:0099604 ligand-gated calcium channel activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.857357264534138 GO:0043130 ubiquitin binding 3/573 100/18639 0.03 0.97586387434555 0.597515370365369 0.857723143310334 GO:0120013 lipid transfer activity 2/573 65/18639 0.0307692307692308 1.00088602496979 0.598201771677885 0.857723143310334 GO:0005261 monoatomic cation channel activity 10/573 341/18639 0.0293255131964809 0.953923630836315 0.605213959902399 0.862213491939759 GO:0140789 histone phosphatase activity 4/573 136/18639 0.0294117647058824 0.956729288574068 0.605285298828124 0.862213491939759 GO:0015215 nucleotide transmembrane transporter activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.862213491939759 GO:0033612 receptor serine/threonine kinase binding 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.862213491939759 GO:0051721 protein phosphatase 2A binding 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.862213491939759 GO:0070566 adenylyltransferase activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.862213491939759 GO:0098918 structural constituent of synapse 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.862213491939759 GO:0008238 exopeptidase activity 3/573 102/18639 0.0294117647058824 0.956729288574068 0.61096149251576 0.864434772881803 GO:0016500 protein-hormone receptor activity 2/573 67/18639 0.0298507462686567 0.971008830194577 0.614753232995124 0.868364302712585 GO:0005244 voltage-gated monoatomic ion channel activity 5/573 173/18639 0.0289017341040462 0.940138607269316 0.617852324852813 0.869664561541146 GO:0140030 modification-dependent protein binding 5/573 173/18639 0.0289017341040462 0.940138607269316 0.617852324852813 0.869664561541146 GO:0016411 acylglycerol O-acyltransferase activity 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.869664561541146 GO:0070273 phosphatidylinositol-4-phosphate binding 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.869664561541146 GO:0003777 microtubule motor activity 2/573 68/18639 0.0294117647058824 0.956729288574068 0.622831086729267 0.869664561541146 GO:0030145 manganese ion binding 2/573 68/18639 0.0294117647058824 0.956729288574068 0.622831086729267 0.869664561541146 GO:0001217 DNA-binding transcription repressor activity 8/573 278/18639 0.0287769784172662 0.936080455007722 0.624957082357118 0.869664561541146 GO:0022832 voltage-gated channel activity 5/573 175/18639 0.0285714285714286 0.929394166043381 0.627965427447719 0.869664561541146 GO:0008094 ATP-dependent activity, acting on DNA 6/573 210/18639 0.0285714285714286 0.929394166043381 0.629050988433678 0.869664561541146 GO:0008378 galactosyltransferase activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.869664561541146 GO:0022884 macromolecule transmembrane transporter activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.869664561541146 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.869664561541146 GO:0071813 lipoprotein particle binding 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.869664561541146 GO:0071814 protein-lipid complex binding 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.869664561541146 GO:0120015 sterol transfer activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.869664561541146 GO:0140142 nucleocytoplasmic carrier activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.869664561541146 GO:0030246 carbohydrate binding 8/573 280/18639 0.0285714285714286 0.929394166043381 0.632945118972119 0.869664561541146 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/573 349/18639 0.0286532951289398 0.932057186576456 0.634295575827029 0.870123418121693 GO:0000149 SNARE binding 3/573 106/18639 0.0283018867924528 0.920626296552405 0.636939133936612 0.8709583045523 GO:0004497 monooxygenase activity 3/573 106/18639 0.0283018867924528 0.920626296552405 0.636939133936612 0.8709583045523 GO:0016782 transferase activity, transferring sulphur-containing groups 2/573 70/18639 0.0285714285714286 0.929394166043381 0.638592699334024 0.871520440955263 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.871520440955263 GO:0019239 deaminase activity 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.871520440955263 GO:0030296 protein tyrosine kinase activator activity 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.871520440955263 GO:0071889 14-3-3 protein binding 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.871520440955263 GO:0140416 transcription regulator inhibitor activity 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.871520440955263 GO:0140299 molecular sensor activity 2/573 71/18639 0.028169014084507 0.916304107366713 0.646277429841664 0.873954944620007 GO:0141003 histone H2AX kinase activity 10/573 354/18639 0.0282485875706215 0.91889253704854 0.65188293801749 0.876545322747622 GO:0022804 active transmembrane transporter activity 13/573 457/18639 0.0284463894967177 0.92532679551365 0.65197798395003 0.876545322747622 GO:0008376 acetylgalactosaminyltransferase activity 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.876545322747622 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.876545322747622 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.876545322747622 GO:0051427 hormone receptor binding 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.876545322747622 GO:0008194 UDP-glycosyltransferase activity 4/573 145/18639 0.0275862068965517 0.89734609135223 0.655360988970185 0.876545322747622 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/573 73/18639 0.0273972602739726 0.891199885247077 0.661257860084715 0.879922855145083 GO:0140996 histone H3 kinase activity 10/573 357/18639 0.0280112044817927 0.911170751022922 0.662206757631423 0.879922855145083 GO:0000175 3'-5'-RNA exonuclease activity 1/573 35/18639 0.0285714285714286 0.929394166043381 0.66508187766223 0.879922855145083 GO:0005154 epidermal growth factor receptor binding 1/573 35/18639 0.0285714285714286 0.929394166043381 0.66508187766223 0.879922855145083 GO:0016229 steroid dehydrogenase activity 1/573 35/18639 0.0285714285714286 0.929394166043381 0.66508187766223 0.879922855145083 GO:0061631 ubiquitin conjugating enzyme activity 1/573 35/18639 0.0285714285714286 0.929394166043381 0.66508187766223 0.879922855145083 GO:0140566 histone reader activity 1/573 35/18639 0.0285714285714286 0.929394166043381 0.66508187766223 0.879922855145083 GO:0019209 kinase activator activity 4/573 148/18639 0.027027027027027 0.879156643554549 0.671072985422614 0.884434784914822 GO:0035173 histone kinase activity 10/573 360/18639 0.0277777777777778 0.903577661431065 0.672354152529957 0.884434784914822 GO:0005484 SNAP receptor activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.884434784914822 GO:0016409 palmitoyltransferase activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.884434784914822 GO:0045505 dynein intermediate chain binding 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.884434784914822 GO:0055106 ubiquitin-protein transferase regulator activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.884434784914822 GO:0044183 protein folding chaperone 2/573 75/18639 0.0266666666666667 0.867434554973822 0.675724707166231 0.884434784914822 GO:0019213 deacetylase activity 1/573 37/18639 0.027027027027027 0.879156643554549 0.685395543027902 0.894357598829092 GO:0030551 cyclic nucleotide binding 1/573 37/18639 0.027027027027027 0.879156643554549 0.685395543027902 0.894357598829092 GO:0005501 retinoid binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.901505930116185 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.901505930116185 GO:0019840 isoprenoid binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.901505930116185 GO:0043531 ADP binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.901505930116185 GO:0019199 transmembrane receptor protein kinase activity 2/573 78/18639 0.0256410256410256 0.834071687474829 0.696477965166892 0.901944233256974 GO:0033293 monocarboxylic acid binding 2/573 79/18639 0.0253164556962025 0.823513818013122 0.703147327835192 0.909205608197771 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/573 39/18639 0.0256410256410256 0.834071687474829 0.704479150664246 0.909553775216583 GO:0004386 helicase activity 4/573 155/18639 0.0258064516129032 0.839452795135957 0.705786887293645 0.909869842655663 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 6/573 229/18639 0.0262008733624454 0.852282859690436 0.709969539048676 0.91388560214386 GO:0004532 RNA exonuclease activity 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.915782808238208 GO:0030331 nuclear estrogen receptor binding 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.915782808238208 GO:0030971 receptor tyrosine kinase binding 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.917663173694721 GO:0032182 ubiquitin-like protein binding 3/573 120/18639 0.025 0.813219895287958 0.718107730267946 0.918834405245682 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/573 268/18639 0.0261194029850746 0.849632726420255 0.720788692786825 0.91884167198818 GO:0001530 lipopolysaccharide binding 1/573 41/18639 0.024390243902439 0.793385263695569 0.72240706220566 0.91884167198818 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/573 41/18639 0.024390243902439 0.793385263695569 0.72240706220566 0.91884167198818 GO:0140318 protein transporter activity 1/573 41/18639 0.024390243902439 0.793385263695569 0.72240706220566 0.91884167198818 GO:0005216 monoatomic ion channel activity 12/573 448/18639 0.0267857142857143 0.871307030665669 0.727111132999528 0.920149187894651 GO:0016758 hexosyltransferase activity 5/573 197/18639 0.0253807106598985 0.825603954607064 0.728034802680831 0.920149187894651 GO:0008528 G protein-coupled peptide receptor activity 3/573 122/18639 0.0245901639344262 0.799888421594713 0.728472493318271 0.920149187894651 GO:0005254 chloride channel activity 2/573 83/18639 0.0240963855421687 0.783826405096827 0.728613911611166 0.920149187894651 GO:0015079 potassium ion transmembrane transporter activity 4/573 160/18639 0.025 0.813219895287958 0.728908606733215 0.920149187894651 GO:0019894 kinesin binding 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.920149187894651 GO:0031492 nucleosomal DNA binding 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.920149187894651 GO:0048156 tau protein binding 1/573 43/18639 0.0232558139534884 0.756483623523682 0.739249151240915 0.929217729019418 GO:0043014 alpha-tubulin binding 1/573 44/18639 0.0227272727272727 0.739290813898144 0.747283687503496 0.937939642966265 GO:0003712 transcription coregulator activity 13/573 495/18639 0.0262626262626263 0.854291607171188 0.757410650519843 0.946247294812567 GO:0001653 peptide receptor activity 3/573 128/18639 0.0234375 0.762393651832461 0.757774792088999 0.946247294812567 GO:0004197 cysteine-type endopeptidase activity 2/573 88/18639 0.0227272727272727 0.739290813898144 0.757819807636603 0.946247294812567 GO:0035591 signaling adaptor activity 3/573 129/18639 0.0232558139534884 0.756483623523682 0.76240209671589 0.946247294812567 GO:0030276 clathrin binding 1/573 46/18639 0.0217391304347826 0.707147735033007 0.762618899637597 0.946247294812567 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/573 130/18639 0.0230769230769231 0.750664518727346 0.766957534298396 0.946247294812567 GO:0005504 fatty acid binding 1/573 47/18639 0.0212765957446809 0.692102038542943 0.76993452221102 0.946247294812567 GO:0099095 ligand-gated monoatomic anion channel activity 1/573 47/18639 0.0212765957446809 0.692102038542943 0.76993452221102 0.946247294812567 GO:0005262 calcium channel activity 3/573 131/18639 0.0229007633587786 0.744934255225611 0.771441670108608 0.946247294812567 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/573 91/18639 0.021978021978022 0.714918589264139 0.774008777934526 0.946247294812567 GO:0035402 histone H3T11 kinase activity 6/573 247/18639 0.0242914979757085 0.790173177607733 0.774715338385053 0.946247294812567 GO:0005179 hormone activity 3/573 132/18639 0.0227272727272727 0.739290813898144 0.775855086175672 0.946247294812567 GO:0052689 carboxylic ester hydrolase activity 2/573 92/18639 0.0217391304347826 0.707147735033007 0.779191415190736 0.946247294812567 GO:0004674 protein serine/threonine kinase activity 11/573 433/18639 0.0254041570438799 0.826366637244115 0.781295663199413 0.946247294812567 GO:0106310 protein serine kinase activity 9/573 361/18639 0.0249307479224377 0.81096720859741 0.783371711599572 0.946247294812567 GO:0005004 GPI-linked ephrin receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0005008 hepatocyte growth factor receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0005009 insulin receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0005011 macrophage colony-stimulating factor receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0005020 stem cell factor receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0008288 boss receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0036332 placental growth factor receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0038062 protein tyrosine kinase collagen receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0060175 brain-derived neurotrophic factor receptor activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.946247294812567 GO:0016410 N-acyltransferase activity 2/573 94/18639 0.0212765957446809 0.692102038542943 0.789245122575823 0.946247294812567 GO:0042562 hormone binding 2/573 94/18639 0.0212765957446809 0.692102038542943 0.789245122575823 0.946247294812567 GO:0005006 epidermal growth factor receptor activity 1/573 50/18639 0.02 0.650575916230367 0.790558398020442 0.946247294812567 GO:0005007 fibroblast growth factor receptor activity 1/573 50/18639 0.02 0.650575916230367 0.790558398020442 0.946247294812567 GO:0005017 platelet-derived growth factor receptor activity 1/573 50/18639 0.02 0.650575916230367 0.790558398020442 0.946247294812567 GO:0005019 platelet-derived growth factor beta-receptor activity 1/573 50/18639 0.02 0.650575916230367 0.790558398020442 0.946247294812567 GO:0032813 tumor necrosis factor receptor superfamily binding 1/573 50/18639 0.02 0.650575916230367 0.790558398020442 0.946247294812567 GO:0099094 ligand-gated monoatomic cation channel activity 3/573 136/18639 0.0220588235294118 0.717546966430551 0.792813722099099 0.946247294812567 GO:0016922 nuclear receptor binding 3/573 137/18639 0.0218978102189781 0.712309397332518 0.796882784576082 0.946247294812567 GO:0005010 insulin-like growth factor receptor activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.946247294812567 GO:0005021 vascular endothelial growth factor receptor activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.946247294812567 GO:0005030 neurotrophin receptor activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.946247294812567 GO:0005272 sodium channel activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.946247294812567 GO:0030544 Hsp70 protein binding 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.946247294812567 GO:0030594 neurotransmitter receptor activity 2/573 97/18639 0.0206185567010309 0.670696820856048 0.803569422421859 0.951637320944996 GO:0030295 protein kinase activator activity 3/573 139/18639 0.0215827338129496 0.702060341255791 0.804820784299139 0.951637320944996 GO:0005003 ephrin receptor activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.951637320944996 GO:0005005 transmembrane-ephrin receptor activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.951637320944996 GO:0017046 peptide hormone binding 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.951637320944996 GO:0038064 collagen receptor activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.951637320944996 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.951637320944996 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/573 181/18639 0.0220994475138122 0.718868415724162 0.811234600512224 0.952560792919703 GO:0140097 catalytic activity, acting on DNA 8/573 336/18639 0.0238095238095238 0.774495138369484 0.814650872045669 0.954615071408252 GO:0017069 snRNA binding 1/573 54/18639 0.0185185185185185 0.60238510762071 0.815214506074103 0.954615071408252 GO:0140297 DNA-binding transcription factor binding 12/573 488/18639 0.0245901639344262 0.799888421594713 0.82301055569479 0.958446718481951 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/573 56/18639 0.0178571428571429 0.580871353777113 0.82643351138994 0.958446718481951 GO:0170055 lipid transmembrane transporter activity 1/573 56/18639 0.0178571428571429 0.580871353777113 0.82643351138994 0.958446718481951 GO:0015276 ligand-gated monoatomic ion channel activity 4/573 186/18639 0.021505376344086 0.699543995946631 0.827510804891445 0.958446718481951 GO:0004722 protein serine/threonine phosphatase activity 2/573 103/18639 0.0194174757281553 0.631627103136278 0.829645676583027 0.958446718481951 GO:0005253 monoatomic anion channel activity 2/573 103/18639 0.0194174757281553 0.631627103136278 0.829645676583027 0.958446718481951 GO:0008234 cysteine-type peptidase activity 4/573 187/18639 0.0213903743315508 0.695803118962959 0.830622696181043 0.958446718481951 GO:0031406 carboxylic acid binding 4/573 187/18639 0.0213903743315508 0.695803118962959 0.830622696181043 0.958446718481951 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/573 57/18639 0.0175438596491228 0.570680628272251 0.831785370507067 0.958446718481951 GO:0016757 glycosyltransferase activity 6/573 267/18639 0.0224719101123595 0.730984175539738 0.833251274993169 0.958446718481951 GO:0022834 ligand-gated channel activity 4/573 188/18639 0.0212765957446809 0.692102038542943 0.833687799590142 0.958446718481951 GO:0046943 carboxylic acid transmembrane transporter activity 4/573 188/18639 0.0212765957446809 0.692102038542943 0.833687799590142 0.958446718481951 GO:0015085 calcium ion transmembrane transporter activity 3/573 147/18639 0.0204081632653061 0.663852975745272 0.834005648494909 0.958446718481951 GO:0005342 organic acid transmembrane transporter activity 4/573 189/18639 0.0211640211640212 0.688440122995097 0.836706551575273 0.958446718481951 GO:0043177 organic acid binding 4/573 189/18639 0.0211640211640212 0.688440122995097 0.836706551575273 0.958446718481951 GO:0008408 3'-5' exonuclease activity 1/573 58/18639 0.0172413793103448 0.560841307095143 0.836972486140446 0.958446718481951 GO:0008514 organic anion transmembrane transporter activity 6/573 269/18639 0.0223048327137546 0.725549348955799 0.838370196006887 0.958446718481951 GO:0004879 nuclear receptor activity 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.958446718481951 GO:0015459 potassium channel regulator activity 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.958446718481951 GO:0036002 pre-mRNA binding 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.958446718481951 GO:0070063 RNA polymerase binding 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.958446718481951 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/573 60/18639 0.0166666666666667 0.542146596858639 0.846872582121376 0.958623113621878 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/573 60/18639 0.0166666666666667 0.542146596858639 0.846872582121376 0.958623113621878 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/573 60/18639 0.0166666666666667 0.542146596858639 0.846872582121376 0.958623113621878 GO:0098531 ligand-modulated transcription factor activity 1/573 60/18639 0.0166666666666667 0.542146596858639 0.846872582121376 0.958623113621878 GO:0016791 phosphatase activity 6/573 273/18639 0.021978021978022 0.714918589264139 0.848227974464009 0.958623113621878 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/573 61/18639 0.0163934426229508 0.533258947729809 0.851595226528742 0.958623113621878 GO:0016836 hydro-lyase activity 1/573 61/18639 0.0163934426229508 0.533258947729809 0.851595226528742 0.958623113621878 GO:0022836 gated channel activity 7/573 318/18639 0.0220125786163522 0.716042675096315 0.861332925906693 0.958623113621878 GO:0004536 DNA nuclease activity 1/573 64/18639 0.015625 0.508262434554974 0.864908463969387 0.958623113621878 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/573 243/18639 0.0205761316872428 0.669316786245233 0.871395372613046 0.958623113621878 GO:0101005 deubiquitinase activity 2/573 115/18639 0.0173913043478261 0.565718188026406 0.872637696540984 0.958623113621878 GO:0008235 metalloexopeptidase activity 1/573 66/18639 0.0151515151515152 0.492860542598763 0.873114713277268 0.958623113621878 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0004711 ribosomal protein S6 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0035175 histone H3S10 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0035979 histone H2AXS139 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0044022 histone H3S28 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0044023 histone H4S1 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0044024 histone H2AS1 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0044025 histone H2BS14 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0072354 histone H3T3 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0072371 histone H2AS121 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0140823 histone H2BS36 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0140855 histone H3S57 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0140995 histone H2A kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0140997 histone H4 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0140998 histone H2B kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:1990244 histone H2AT120 kinase activity 5/573 245/18639 0.0204081632653061 0.663852975745272 0.875825270080996 0.958623113621878 GO:0042054 histone methyltransferase activity 1/573 67/18639 0.0149253731343284 0.485504415097288 0.877029281160331 0.958623113621878 GO:0004677 DNA-dependent protein kinase activity 5/573 246/18639 0.0203252032520325 0.661154386412974 0.877991262943402 0.958623113621878 GO:0140857 histone H3T45 kinase activity 5/573 246/18639 0.0203252032520325 0.661154386412974 0.877991262943402 0.958623113621878 GO:0035403 histone H3T6 kinase activity 5/573 247/18639 0.0202429149797571 0.658477648006444 0.880125063037583 0.959391410263356 GO:0004679 AMP-activated protein kinase activity 5/573 248/18639 0.0201612903225806 0.655822496199966 0.882227004537697 0.959391410263356 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 11/573 484/18639 0.0227272727272727 0.739290813898144 0.882564637784669 0.959391410263356 GO:0016279 protein-lysine N-methyltransferase activity 1/573 69/18639 0.0144927536231884 0.471431823355338 0.884500428978141 0.959391410263356 GO:0098960 postsynaptic neurotransmitter receptor activity 1/573 69/18639 0.0144927536231884 0.471431823355338 0.884500428978141 0.959391410263356 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/573 70/18639 0.0142857142857143 0.46469708302169 0.88806430911791 0.959391410263356 GO:0016278 lysine N-methyltransferase activity 1/573 70/18639 0.0142857142857143 0.46469708302169 0.88806430911791 0.959391410263356 GO:0004540 RNA nuclease activity 2/573 121/18639 0.0165289256198347 0.537666046471377 0.890170164204703 0.959391410263356 GO:0015108 chloride transmembrane transporter activity 2/573 121/18639 0.0165289256198347 0.537666046471377 0.890170164204703 0.959391410263356 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/573 167/18639 0.0179640718562874 0.584349625356617 0.891023564438514 0.959391410263356 GO:0016874 ligase activity 3/573 167/18639 0.0179640718562874 0.584349625356617 0.891023564438514 0.959391410263356 GO:0001216 DNA-binding transcription activator activity 11/573 491/18639 0.0224032586558045 0.728751026327294 0.89291078243792 0.960215615284999 GO:0004521 RNA endonuclease activity 1/573 73/18639 0.0136986301369863 0.445599942623539 0.898110658682519 0.963386871970221 GO:0043539 protein serine/threonine kinase activator activity 1/573 73/18639 0.0136986301369863 0.445599942623539 0.898110658682519 0.963386871970221 GO:0031491 nucleosome binding 1/573 74/18639 0.0135135135135135 0.439578321777275 0.901255255934212 0.965550061426389 GO:0004519 endonuclease activity 2/573 127/18639 0.015748031496063 0.512264500968793 0.905441447757447 0.967612833059145 GO:0019783 ubiquitin-like protein peptidase activity 2/573 127/18639 0.015748031496063 0.512264500968793 0.905441447757447 0.967612833059145 GO:0051536 iron-sulfur cluster binding 1/573 76/18639 0.0131578947368421 0.428010471204189 0.907256769136721 0.968221422977232 GO:0051540 metal cluster binding 1/573 77/18639 0.012987012987013 0.422451893656082 0.910119553777386 0.968221422977232 GO:0015370 solute:sodium symporter activity 1/573 79/18639 0.0126582278481013 0.411756909006561 0.915583181299493 0.968221422977232 GO:0016835 carbon-oxygen lyase activity 1/573 79/18639 0.0126582278481013 0.411756909006561 0.915583181299493 0.968221422977232 GO:0000049 tRNA binding 1/573 80/18639 0.0125 0.406609947643979 0.918189368644072 0.968221422977232 GO:0033192 calmodulin-dependent protein phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:0140791 histone H2AXS140 phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/573 81/18639 0.0123456790123457 0.40159007174714 0.920715231662928 0.968221422977232 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/573 82/18639 0.0121951219512195 0.396692631847784 0.923163241807186 0.968416341895774 GO:0033549 MAP kinase phosphatase activity 1/573 82/18639 0.0121951219512195 0.396692631847784 0.923163241807186 0.968416341895774 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/573 83/18639 0.0120481927710843 0.391913202548414 0.925535794614455 0.968531344975518 GO:0030165 PDZ domain binding 1/573 83/18639 0.0120481927710843 0.391913202548414 0.925535794614455 0.968531344975518 GO:0004527 exonuclease activity 1/573 84/18639 0.0119047619047619 0.387247569184742 0.927835212036632 0.968569440857752 GO:0017018 myosin phosphatase activity 1/573 84/18639 0.0119047619047619 0.387247569184742 0.927835212036632 0.968569440857752 GO:0051213 dioxygenase activity 1/573 93/18639 0.010752688172043 0.349771997973315 0.945588362821622 0.985171199622553 GO:0008509 monoatomic anion transmembrane transporter activity 2/573 149/18639 0.0134228187919463 0.436628131698233 0.946040567861844 0.985171199622553 GO:0008276 protein methyltransferase activity 1/573 95/18639 0.0105263157894737 0.342408376963351 0.948898731061211 0.986946918333411 GO:0016407 acetyltransferase activity 1/573 96/18639 0.0104166666666667 0.338841623036649 0.950477733816923 0.986970926038223 GO:0003714 transcription corepressor activity 3/573 204/18639 0.0147058823529412 0.478364644287034 0.952380823490155 0.986970926038223 GO:0008168 methyltransferase activity 3/573 204/18639 0.0147058823529412 0.478364644287034 0.952380823490155 0.986970926038223 GO:0004518 nuclease activity 3/573 209/18639 0.0143540669856459 0.466920514040933 0.957596285566407 0.991175840924843 GO:0015171 amino acid transmembrane transporter activity 1/573 102/18639 0.00980392156862745 0.318909762858023 0.958979799524825 0.99140906810779 GO:0003730 mRNA 3'-UTR binding 4/573 262/18639 0.0152671755725191 0.496622836817074 0.962244552907447 0.992300285034022 GO:0016741 transferase activity, transferring one-carbon groups 3/573 215/18639 0.013953488372093 0.453890174114209 0.963148492050793 0.992300285034022 GO:0015081 sodium ion transmembrane transporter activity 2/573 164/18639 0.0121951219512195 0.396692631847784 0.963530344326046 0.992300285034022 GO:0015103 inorganic anion transmembrane transporter activity 2/573 165/18639 0.0121212121212121 0.39428843407901 0.964478781715311 0.992300285034022 GO:0004843 cysteine-type deubiquitinase activity 1/573 108/18639 0.00925925925925926 0.301192553810355 0.966024320947847 0.992697261382181 GO:0046873 metal ion transmembrane transporter activity 8/573 450/18639 0.0177777777777778 0.578289703315881 0.968842677261702 0.993451798144964 GO:0005549 odorant binding 1/573 111/18639 0.00900900900900901 0.293052214518183 0.969079733003557 0.993451798144964 GO:0015294 solute:monoatomic cation symporter activity 1/573 116/18639 0.00862068965517241 0.280420653547572 0.973574689997584 0.996865950523842 GO:0003697 single-stranded DNA binding 1/573 121/18639 0.00826446280991736 0.268833023235689 0.977417176718542 0.998846869066228 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/573 122/18639 0.00819672131147541 0.266629473864904 0.97811595400228 0.998846869066228 GO:0140098 catalytic activity, acting on RNA 6/573 387/18639 0.0155038759689922 0.504322415682455 0.98065011559047 0.998846869066228 GO:0031490 chromatin DNA binding 1/573 128/18639 0.0078125 0.254131217277487 0.981877914020613 0.998846869066228 GO:0031072 heat shock protein binding 1/573 131/18639 0.00763358778625954 0.248311418408537 0.983509327961954 0.998846869066228 GO:0061630 ubiquitin protein ligase activity 5/573 353/18639 0.0141643059490085 0.460747816027172 0.985164870261011 0.998846869066228 GO:0015297 antiporter activity 1/573 135/18639 0.00740740740740741 0.240954043048284 0.985458760861749 0.998846869066228 GO:0016779 nucleotidyltransferase activity 1/573 136/18639 0.00735294117647059 0.239182322143517 0.985909048908993 0.998846869066228 GO:0016829 lyase activity 2/573 200/18639 0.01 0.325287958115183 0.986096579383893 0.998846869066228 GO:0140767 enzyme-substrate adaptor activity 1/573 139/18639 0.00719424460431655 0.23402011375193 0.987178097231342 0.998846869066228 GO:0015293 symporter activity 1/573 146/18639 0.00684931506849315 0.222799971311769 0.98971301873647 0.999100239423271 GO:0061659 ubiquitin-like protein ligase activity 5/573 372/18639 0.0134408602150538 0.437214997466644 0.990171408009181 0.999100239423271 GO:0019842 vitamin binding 1/573 150/18639 0.00666666666666667 0.216858638743456 0.990930027184997 0.999100239423271 GO:0015291 secondary active transmembrane transporter activity 3/573 287/18639 0.0104529616724739 0.34002225586953 0.993689411858313 0.999327072088537 GO:0016755 aminoacyltransferase activity 7/573 496/18639 0.0141129032258065 0.459075747339976 0.994532554086625 0.999327072088537 GO:0004842 ubiquitin-protein transferase activity 6/573 449/18639 0.0133630289532294 0.434683240243007 0.994657319415226 0.999327072088537 GO:0019787 ubiquitin-like protein transferase activity 6/573 479/18639 0.0125260960334029 0.407458820186033 0.997223644433741 0.99999821190779 GO:0042393 histone binding 1/573 247/18639 0.00404858299595142 0.131695529601289 0.999575501667095 0.99999821190779 GO:0045182 translation regulator activity 2/573 356/18639 0.00561797752808989 0.182746043884934 0.99983303109206 0.99999821190779 GO:0004984 olfactory receptor activity 1/573 419/18639 0.00238663484486874 0.0776343575453898 0.99999821190779 0.99999821190779