ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 60/443 175/18639 0.342857142857143 14.4255401483392 2.63207045933819e-53 1.89245866026416e-50 GO:0005201 extracellular matrix structural constituent 37/443 168/18639 0.220238095238095 9.26640599806514 2.32243579773393e-25 8.34915669285347e-23 GO:0019843 rRNA binding 17/443 65/18639 0.261538461538462 11.004097933669 1.19146523233464e-13 2.8555450068287e-11 GO:0008201 heparin binding 23/443 172/18639 0.133720930232558 5.62624022258386 2.0974551071449e-11 3.77017555509295e-09 GO:0005539 glycosaminoglycan binding 27/443 242/18639 0.111570247933884 4.6942615152137 2.76287361622088e-11 3.97301226012562e-09 GO:0048407 platelet-derived growth factor binding 7/443 11/18639 0.636363636363636 26.7746767904781 1.24239320836117e-09 1.48880119468614e-07 GO:1901681 sulfur compound binding 26/443 275/18639 0.0945454545454545 3.97795198029961 2.40883081835285e-09 2.47421336913672e-07 GO:0019838 growth factor binding 18/443 136/18639 0.132352941176471 5.56868277785155 3.8584372129206e-09 3.46777044511239e-07 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/443 44/18639 0.25 10.5186230248307 4.57154714696097e-09 3.65215822073882e-07 GO:0005518 collagen binding 12/443 72/18639 0.166666666666667 7.01241534988713 1.18417141914368e-07 8.51419250364303e-06 GO:0004857 enzyme inhibitor activity 29/443 416/18639 0.0697115384615385 2.93307757423164 2.57059215623721e-07 1.68023250939505e-05 GO:0005178 integrin binding 17/443 161/18639 0.105590062111801 4.44264823408998 3.02911652072709e-07 1.81494564866898e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/443 15/18639 0.4 16.8297968397291 7.27147883305384e-07 4.02168713920439e-05 GO:1990948 ubiquitin ligase inhibitor activity 5/443 11/18639 0.454545454545455 19.1247691360558 3.0441398095271e-06 0.000156338323074999 GO:0050840 extracellular matrix binding 10/443 67/18639 0.149253731343284 6.27977494019743 3.83981979387415e-06 0.000184055362119701 GO:0045296 cadherin binding 23/443 334/18639 0.0688622754491018 2.89734526432462 5.54476885648039e-06 0.000249168050488087 GO:0048027 mRNA 5'-UTR binding 6/443 24/18639 0.25 10.5186230248307 1.63036348849188e-05 0.000689547851897448 GO:0061134 peptidase regulator activity 17/443 226/18639 0.0752212389380531 3.16489542340039 3.05092350195251e-05 0.00121867444327992 GO:0016209 antioxidant activity 10/443 86/18639 0.116279069767442 4.89238280224684 3.66888971723905e-05 0.00138838510878678 GO:0001968 fibronectin binding 6/443 30/18639 0.2 8.41489841986456 6.37373328254577e-05 0.00224109444530752 GO:0005520 insulin-like growth factor binding 5/443 19/18639 0.263157894736842 11.0722347629797 6.54561659964645e-05 0.00224109444530752 GO:0001540 amyloid-beta binding 9/443 83/18639 0.108433734939759 4.56229432402295 0.000154759384309805 0.00505781805994317 GO:0055106 ubiquitin-protein transferase regulator activity 6/443 36/18639 0.166666666666667 7.01241534988713 0.000185340160827141 0.00568660838419446 GO:0031994 insulin-like growth factor I binding 4/443 13/18639 0.307692307692308 12.9459975690224 0.000189817247872972 0.00568660838419446 GO:0043394 proteoglycan binding 6/443 37/18639 0.162162162162162 6.82289061070099 0.000216819731904629 0.00623573548957713 GO:0140313 molecular sequestering activity 7/443 55/18639 0.127272727272727 5.35493535809563 0.000309643597749324 0.00856283641468322 GO:0016504 peptidase activator activity 7/443 57/18639 0.12280701754386 5.16704288939052 0.000387318202410136 0.0103141402789958 GO:0002020 protease binding 11/443 136/18639 0.0808823529411765 3.40308391979817 0.000409941847852992 0.0105267210216536 GO:0003746 translation elongation factor activity 4/443 18/18639 0.222222222222222 9.34988713318285 0.000739249891046808 0.0177173557220885 GO:0098641 cadherin binding involved in cell-cell adhesion 4/443 18/18639 0.222222222222222 9.34988713318285 0.000739249891046808 0.0177173557220885 GO:0008135 translation factor activity, RNA binding 8/443 83/18639 0.0963855421686747 4.05537273246485 0.000794198894088729 0.0184202904790257 GO:0180051 translation factor activity 8/443 84/18639 0.0952380952380952 4.00709448564979 0.000859930411525017 0.0193215614339527 GO:1990841 promoter-specific chromatin binding 7/443 68/18639 0.102941176470588 4.33119771610676 0.00113575228217562 0.024745633057099 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/443 22/18639 0.181818181818182 7.64990765442233 0.00163921711923869 0.0346646208450771 GO:0044389 ubiquitin-like protein ligase binding 17/443 322/18639 0.0527950310559006 2.22132411704499 0.00190249405204273 0.0390826635262492 GO:0031625 ubiquitin protein ligase binding 16/443 302/18639 0.0529801324503311 2.22911216420253 0.00246810504855087 0.0492935424974465 GO:0042277 peptide binding 14/443 249/18639 0.0562248995983936 2.36563409393783 0.0026391213848501 0.0512845479920871 GO:0048306 calcium-dependent protein binding 7/443 80/18639 0.0875 3.68151805869074 0.00291950799023539 0.0552401643415591 GO:0008191 metalloendopeptidase inhibitor activity 3/443 14/18639 0.214285714285714 9.01596259271203 0.00399320796067142 0.0736183724031474 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 5/443 46/18639 0.108695652173913 4.57331435862204 0.00456017953344465 0.0819692271136676 GO:0008083 growth factor activity 10/443 162/18639 0.0617283950617284 2.59719087032857 0.00545271192556196 0.0942758798695454 GO:0032934 sterol binding 6/443 68/18639 0.0882352941176471 3.71245518523437 0.00550707504105828 0.0942758798695454 GO:0070325 lipoprotein particle receptor binding 4/443 31/18639 0.129032258064516 5.42896672249326 0.00595927586257567 0.0996446359346954 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/443 17/18639 0.176470588235294 7.42491037046873 0.00707597360527027 0.115627841413394 GO:0030414 peptidase inhibitor activity 10/443 169/18639 0.0591715976331361 2.48961491711969 0.00728594861060914 0.116413267800622 GO:0140311 protein sequestering activity 4/443 33/18639 0.121212121212121 5.09993843628155 0.00746695726165956 0.116711788502896 GO:0051082 unfolded protein binding 8/443 121/18639 0.0661157024793388 2.78178460160812 0.00833135962366754 0.12242542637336 GO:0004864 protein phosphatase inhibitor activity 5/443 53/18639 0.0943396226415094 3.96929170748328 0.00834190583789655 0.12242542637336 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/443 18/18639 0.166666666666667 7.01241534988713 0.00834331834811495 0.12242542637336 GO:0015485 cholesterol binding 5/443 54/18639 0.0925925925925926 3.89578630549285 0.00901809936590392 0.129680268881698 GO:0098631 cell adhesion mediator activity 6/443 76/18639 0.0789473684210526 3.32167042889391 0.00939467668972625 0.132446520390454 GO:0043395 heparan sulfate proteoglycan binding 3/443 19/18639 0.157894736842105 6.64334085778781 0.00973539149756271 0.134610509360531 GO:0019212 phosphatase inhibitor activity 5/443 56/18639 0.0892857142857143 3.75665108029668 0.0104820586219919 0.142200002815324 GO:0043024 ribosomal small subunit binding 3/443 20/18639 0.15 6.31117381489842 0.0112544725213899 0.144719810958509 GO:0046332 SMAD binding 6/443 79/18639 0.0759493670886076 3.19553104551819 0.011260793450099 0.144719810958509 GO:0004601 peroxidase activity 5/443 57/18639 0.087719298245614 3.69074492099323 0.0112716403528185 0.144719810958509 GO:0061135 endopeptidase regulator activity 10/443 184/18639 0.0543478260869565 2.28665717931102 0.0127905958624282 0.158062764914116 GO:0010314 phosphatidylinositol-5-phosphate binding 3/443 21/18639 0.142857142857143 6.01064172847469 0.0129024530151599 0.158062764914116 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/443 59/18639 0.0847457627118644 3.56563492367142 0.0129703798747328 0.158062764914116 GO:0003924 GTPase activity 15/443 331/18639 0.0453172205438066 1.90669903773366 0.0132264727659628 0.158497231978788 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/443 40/18639 0.1 4.20744920993228 0.0146480931173943 0.169722530319022 GO:0004860 protein kinase inhibitor activity 6/443 84/18639 0.0714285714285714 3.00532086423734 0.014928994520754 0.169722530319022 GO:0004866 endopeptidase inhibitor activity 9/443 161/18639 0.0559006211180124 2.35199024157705 0.0149851202180539 0.169722530319022 GO:0033218 amide binding 12/443 247/18639 0.048582995951417 2.04410487931933 0.0154569251659355 0.169722530319022 GO:0019001 guanyl nucleotide binding 17/443 400/18639 0.0425 1.78816591422122 0.0155795368582134 0.169722530319022 GO:0032561 guanyl ribonucleotide binding 17/443 400/18639 0.0425 1.78816591422122 0.0155795368582134 0.169722530319022 GO:0042169 SH2 domain binding 4/443 41/18639 0.0975609756097561 4.10482849749491 0.0159347722768852 0.171001511448963 GO:0042056 chemoattractant activity 4/443 42/18639 0.0952380952380952 4.00709448564979 0.0172902619463248 0.182819093226582 GO:0008236 serine-type peptidase activity 10/443 194/18639 0.0515463917525773 2.16878825254241 0.0179027490672432 0.186551834483303 GO:0050431 transforming growth factor beta binding 3/443 24/18639 0.125 5.25931151241535 0.0186333442676121 0.188695415893142 GO:0060229 lipase activator activity 3/443 24/18639 0.125 5.25931151241535 0.0186333442676121 0.188695415893142 GO:0038024 cargo receptor activity 5/443 65/18639 0.0769230769230769 3.2364993922556 0.0190812583755546 0.190547566278107 GO:0017171 serine hydrolase activity 10/443 198/18639 0.0505050505050505 2.12497434845065 0.020320799097103 0.197583947687713 GO:0019210 kinase inhibitor activity 6/443 90/18639 0.0666666666666667 2.80496613995485 0.0203354827940067 0.197583947687713 GO:0008239 dipeptidyl-peptidase activity 2/443 10/18639 0.2 8.41489841986456 0.0223540768623807 0.209150224588706 GO:0030957 Tat protein binding 2/443 10/18639 0.2 8.41489841986456 0.0223540768623807 0.209150224588706 GO:0043178 alcohol binding 6/443 92/18639 0.0652173913043478 2.74398861517323 0.0223985636903065 0.209150224588706 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 5/443 68/18639 0.0735294117647059 3.09371265436197 0.0227433366000012 0.209646910453857 GO:0050750 low-density lipoprotein particle receptor binding 3/443 26/18639 0.115384615384615 4.8547490883834 0.023117594519921 0.210399372909154 GO:0004252 serine-type endopeptidase activity 9/443 176/18639 0.0511363636363636 2.15153652780628 0.0251005741585406 0.222290821491866 GO:0097110 scaffold protein binding 5/443 70/18639 0.0714285714285714 3.00532086423734 0.0254209755168288 0.222290821491866 GO:0004867 serine-type endopeptidase inhibitor activity 6/443 95/18639 0.0631578947368421 2.65733634311512 0.0257501779447967 0.222290821491866 GO:0008199 ferric iron binding 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.222290821491866 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.222290821491866 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.222290821491866 GO:0050786 RAGE receptor binding 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.222290821491866 GO:0097493 structural molecule activity conferring elasticity 2/443 11/18639 0.181818181818182 7.64990765442233 0.026897498567166 0.222290821491866 GO:0051393 alpha-actinin binding 3/443 28/18639 0.107142857142857 4.50798129635601 0.0281346764563712 0.229873095137851 GO:0001222 transcription corepressor binding 4/443 49/18639 0.0816326530612245 3.43465241627125 0.0287790352563084 0.232495801677368 GO:0043236 laminin binding 3/443 29/18639 0.103448275862069 4.35253366544719 0.0308422423638647 0.246395247329097 GO:0004859 phospholipase inhibitor activity 2/443 12/18639 0.166666666666667 7.01241534988713 0.0317769451851295 0.248343734653349 GO:0097371 MDM2/MDM4 family protein binding 2/443 12/18639 0.166666666666667 7.01241534988713 0.0317769451851295 0.248343734653349 GO:0005126 cytokine receptor binding 12/443 275/18639 0.0436363636363636 1.83597783706136 0.0322027064197672 0.248965009847448 GO:0003743 translation initiation factor activity 4/443 51/18639 0.0784313725490196 3.29996016465277 0.0327241781766102 0.250305150095561 GO:0005080 protein kinase C binding 4/443 52/18639 0.0769230769230769 3.2364993922556 0.0348093882234944 0.263452106659921 GO:0003724 RNA helicase activity 5/443 77/18639 0.0649350649350649 2.7321098765794 0.0363432318738881 0.271268086755829 GO:0017147 Wnt-protein binding 3/443 31/18639 0.0967741935483871 4.07172504186995 0.0366518615128694 0.271268086755829 GO:0045159 myosin II binding 2/443 13/18639 0.153846153846154 6.4729987845112 0.0369739534103911 0.271268086755829 GO:0031267 small GTPase binding 12/443 283/18639 0.0424028268551237 1.78407740350485 0.0387608448902927 0.281393240828468 GO:0051287 NAD binding 4/443 54/18639 0.0740740740740741 3.11662904439428 0.0392061510036482 0.281393240828468 GO:0031369 translation initiation factor binding 3/443 32/18639 0.09375 3.94448363431151 0.0397518790957473 0.281393240828468 GO:0008186 ATP-dependent activity, acting on RNA 5/443 79/18639 0.0632911392405063 2.66294253793182 0.0399194861815073 0.281393240828468 GO:0098632 cell-cell adhesion mediator activity 4/443 55/18639 0.0727272727272727 3.05996306176893 0.0415179136417383 0.28538752490775 GO:0019888 protein phosphatase regulator activity 6/443 107/18639 0.0560747663551402 2.35931731398072 0.0424274080321663 0.28538752490775 GO:0005161 platelet-derived growth factor receptor binding 2/443 14/18639 0.142857142857143 6.01064172847469 0.0424707443186777 0.28538752490775 GO:0042043 neurexin family protein binding 2/443 14/18639 0.142857142857143 6.01064172847469 0.0424707443186777 0.28538752490775 GO:0044548 S100 protein binding 2/443 14/18639 0.142857142857143 6.01064172847469 0.0424707443186777 0.28538752490775 GO:0005496 steroid binding 6/443 108/18639 0.0555555555555556 2.33747178329571 0.044063639535067 0.293349600238085 GO:0019825 oxygen binding 3/443 34/18639 0.0882352941176471 3.71245518523437 0.0463358792788744 0.301668650400578 GO:0004129 cytochrome-c oxidase activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.301668650400578 GO:0005041 low-density lipoprotein particle receptor activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.301668650400578 GO:0030553 cGMP binding 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.301668650400578 GO:0031386 protein tag activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.301668650400578 GO:0051371 muscle alpha-actinin binding 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.301668650400578 GO:0141047 molecular tag activity 2/443 15/18639 0.133333333333333 5.60993227990971 0.0482502013853498 0.301668650400578 GO:0043022 ribosome binding 6/443 112/18639 0.0535714285714286 2.25399064817801 0.0509998029089387 0.316110847340749 GO:0020037 heme binding 7/443 142/18639 0.0492957746478873 2.07409468095253 0.0531702460459175 0.31998947167706 GO:0005024 transforming growth factor beta receptor activity 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.31998947167706 GO:0008142 oxysterol binding 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.31998947167706 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.31998947167706 GO:0016722 oxidoreductase activity, acting on metal ions 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.31998947167706 GO:0055102 lipase inhibitor activity 2/443 16/18639 0.125 5.25931151241535 0.054295849157999 0.31998947167706 GO:0019903 protein phosphatase binding 7/443 144/18639 0.0486111111111111 2.04528781038375 0.0565048808852478 0.326104573889342 GO:0019955 cytokine binding 7/443 144/18639 0.0486111111111111 2.04528781038375 0.0565048808852478 0.326104573889342 GO:0015026 coreceptor activity 4/443 61/18639 0.0655737704918033 2.75898308848018 0.0569716776924712 0.326104573889342 GO:0042805 actinin binding 3/443 37/18639 0.0810810810810811 3.4114453053505 0.0571476721975759 0.326104573889342 GO:0009055 electron transfer activity 6/443 116/18639 0.0517241379310345 2.17626683272359 0.0585679033554285 0.331577342618528 GO:0019208 phosphatase regulator activity 6/443 117/18639 0.0512820512820513 2.15766626150373 0.0605592807704672 0.332561279498139 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.332561279498139 GO:0016018 cyclosporin A binding 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.332561279498139 GO:0045236 CXCR chemokine receptor binding 2/443 17/18639 0.117647058823529 4.94994024697915 0.0605918325650296 0.332561279498139 GO:0043021 ribonucleoprotein complex binding 8/443 177/18639 0.0451977401129944 1.90167195929143 0.0611933295689142 0.333318211818555 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.357491576514826 GO:0030228 lipoprotein particle receptor activity 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.357491576514826 GO:0034185 apolipoprotein binding 2/443 18/18639 0.111111111111111 4.67494356659142 0.0671228968421439 0.357491576514826 GO:0005525 GTP binding 14/443 378/18639 0.037037037037037 1.55831452219714 0.0686080180543442 0.362316202518904 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/443 40/18639 0.075 3.15558690744921 0.0690366060432404 0.362316202518904 GO:0046906 tetrapyrrole binding 7/443 152/18639 0.0460526315789474 1.93764108352144 0.0711190449910338 0.370540531511256 GO:0051020 GTPase binding 12/443 315/18639 0.0380952380952381 1.60283779425992 0.0742859417563267 0.3834346190259 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 13/443 349/18639 0.0372492836676218 1.56724469137879 0.0746604265140834 0.3834346190259 GO:0008307 structural constituent of muscle 3/443 42/18639 0.0714285714285714 3.00532086423734 0.0775318248567418 0.39257311318308 GO:0035198 miRNA binding 3/443 42/18639 0.0714285714285714 3.00532086423734 0.0775318248567418 0.39257311318308 GO:0016004 phospholipase activator activity 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.400815893181942 GO:0016505 peptidase activator activity involved in apoptotic process 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.400815893181942 GO:0042288 MHC class I protein binding 2/443 20/18639 0.1 4.20744920993228 0.0808321342300161 0.400815893181942 GO:0030547 signaling receptor inhibitor activity 3/443 44/18639 0.0681818181818182 2.86871537040837 0.086459980588018 0.424560461781424 GO:0035591 signaling adaptor activity 6/443 129/18639 0.0465116279069767 1.95695312089873 0.0875528802797775 0.424560461781424 GO:0035613 RNA stem-loop binding 2/443 21/18639 0.0952380952380952 4.00709448564979 0.0879826269894745 0.424560461781424 GO:0036122 BMP binding 2/443 21/18639 0.0952380952380952 4.00709448564979 0.0879826269894745 0.424560461781424 GO:0008009 chemokine activity 3/443 45/18639 0.0666666666666667 2.80496613995485 0.0910800381726278 0.436576982974129 GO:0042379 chemokine receptor binding 4/443 72/18639 0.0555555555555556 2.33747178329571 0.0921444390137557 0.438753984442982 GO:0017134 fibroblast growth factor binding 2/443 23/18639 0.0869565217391304 3.65865148689763 0.102810130814215 0.48314041866288 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/443 23/18639 0.0869565217391304 3.65865148689763 0.102810130814215 0.48314041866288 GO:0004175 endopeptidase activity 14/443 405/18639 0.0345679012345679 1.454426887384 0.104787275341514 0.489234097211354 GO:0032266 phosphatidylinositol-3-phosphate binding 3/443 48/18639 0.0625 2.62965575620767 0.105532245617074 0.489533449023718 GO:0005125 cytokine activity 9/443 234/18639 0.0384615384615385 1.6182496961278 0.107025996927605 0.493280075582999 GO:0008013 beta-catenin binding 5/443 106/18639 0.0471698113207547 1.98464585374164 0.108422148475113 0.496391155759451 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/443 24/18639 0.0833333333333333 3.50620767494357 0.110462565954815 0.496391155759451 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/443 24/18639 0.0833333333333333 3.50620767494357 0.110462565954815 0.496391155759451 GO:0035035 histone acetyltransferase binding 2/443 24/18639 0.0833333333333333 3.50620767494357 0.110462565954815 0.496391155759451 GO:0019199 transmembrane receptor protein kinase activity 4/443 78/18639 0.0512820512820513 2.15766626150373 0.11479518608615 0.512656762707714 GO:0032813 tumor necrosis factor receptor superfamily binding 3/443 50/18639 0.06 2.52446952595937 0.115633021709195 0.513210756845132 GO:0008483 transaminase activity 2/443 25/18639 0.08 3.36595936794582 0.118258542901613 0.517630135161325 GO:0120020 cholesterol transfer activity 2/443 25/18639 0.08 3.36595936794582 0.118258542901613 0.517630135161325 GO:0016835 carbon-oxygen lyase activity 4/443 79/18639 0.0506329113924051 2.13035403034546 0.118788556747731 0.517630135161325 GO:1902936 phosphatidylinositol bisphosphate binding 5/443 111/18639 0.045045045045045 1.89524739186139 0.125053870568789 0.530575560449097 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.530575560449097 GO:0008143 poly(A) binding 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.530575560449097 GO:0008198 ferrous iron binding 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.530575560449097 GO:0050681 nuclear androgen receptor binding 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.530575560449097 GO:0070412 R-SMAD binding 2/443 26/18639 0.0769230769230769 3.2364993922556 0.126186955266753 0.530575560449097 GO:0030971 receptor tyrosine kinase binding 4/443 81/18639 0.0493827160493827 2.07775269626285 0.126952497079771 0.530690961629975 GO:0005200 structural constituent of cytoskeleton 5/443 112/18639 0.0446428571428571 1.87832554014834 0.128514341020184 0.534114515569436 GO:0030246 carbohydrate binding 10/443 280/18639 0.0357142857142857 1.50266043211867 0.132095696960326 0.545843713301578 GO:0005044 scavenger receptor activity 2/443 27/18639 0.0740740740740741 3.11662904439428 0.134237141366754 0.548389230924411 GO:0005104 fibroblast growth factor receptor binding 2/443 27/18639 0.0740740740740741 3.11662904439428 0.134237141366754 0.548389230924411 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/443 28/18639 0.0714285714285714 3.00532086423734 0.142398869436784 0.578445125000269 GO:1990782 protein tyrosine kinase binding 5/443 117/18639 0.0427350427350427 1.79805521791978 0.146453872348745 0.591574911341278 GO:0008237 metallopeptidase activity 7/443 184/18639 0.0380434782608696 1.60066002551772 0.149636069196899 0.59982432006753 GO:0022853 active monoatomic ion transmembrane transporter activity 5/443 118/18639 0.0423728813559322 1.78281746183571 0.150164642019688 0.59982432006753 GO:0015078 proton transmembrane transporter activity 7/443 185/18639 0.0378378378378378 1.59200780916357 0.152574758415569 0.606084261330354 GO:0001965 G-protein alpha-subunit binding 2/443 30/18639 0.0666666666666667 2.80496613995485 0.159018088437279 0.619020371833161 GO:0016769 transferase activity, transferring nitrogenous groups 2/443 30/18639 0.0666666666666667 2.80496613995485 0.159018088437279 0.619020371833161 GO:0051721 protein phosphatase 2A binding 2/443 30/18639 0.0666666666666667 2.80496613995485 0.159018088437279 0.619020371833161 GO:0061980 regulatory RNA binding 3/443 58/18639 0.0517241379310345 2.17626683272359 0.15927506090283 0.619020371833161 GO:0005506 iron ion binding 6/443 154/18639 0.038961038961039 1.63926592594764 0.161174703932299 0.623035549071631 GO:0001786 phosphatidylserine binding 3/443 59/18639 0.0508474576271186 2.13938095420285 0.165047649782981 0.62786414410121 GO:0004879 nuclear receptor activity 3/443 59/18639 0.0508474576271186 2.13938095420285 0.165047649782981 0.62786414410121 GO:0036002 pre-mRNA binding 3/443 59/18639 0.0508474576271186 2.13938095420285 0.165047649782981 0.62786414410121 GO:0005164 tumor necrosis factor receptor binding 2/443 31/18639 0.0645161290322581 2.71448336124663 0.167457138569997 0.62786414410121 GO:0070273 phosphatidylinositol-4-phosphate binding 2/443 31/18639 0.0645161290322581 2.71448336124663 0.167457138569997 0.62786414410121 GO:0019902 phosphatase binding 7/443 190/18639 0.0368421052631579 1.55011286681716 0.167663304127166 0.62786414410121 GO:0098531 ligand-modulated transcription factor activity 3/443 60/18639 0.05 2.10372460496614 0.170881286191561 0.636599195708458 GO:0051059 NF-kappaB binding 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.638692984083609 GO:0070717 poly-purine tract binding 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.638692984083609 GO:0071813 lipoprotein particle binding 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.638692984083609 GO:0071814 protein-lipid complex binding 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.638692984083609 GO:0120015 sterol transfer activity 2/443 32/18639 0.0625 2.62965575620767 0.175970822534947 0.638692984083609 GO:0016836 hydro-lyase activity 3/443 61/18639 0.0491803278688525 2.06923731636014 0.176773162493238 0.638692984083609 GO:0140416 transcription regulator inhibitor activity 2/443 33/18639 0.0606060606060606 2.54996921814078 0.184550851648224 0.663460311675365 GO:0140297 DNA-binding transcription factor binding 15/443 488/18639 0.0307377049180328 1.29327332272509 0.187758832945469 0.668500999719201 GO:0008376 acetylgalactosaminyltransferase activity 2/443 34/18639 0.0588235294117647 2.47497012348958 0.193189287421308 0.668500999719201 GO:0015035 protein-disulfide reductase activity 2/443 34/18639 0.0588235294117647 2.47497012348958 0.193189287421308 0.668500999719201 GO:0030332 cyclin binding 2/443 34/18639 0.0588235294117647 2.47497012348958 0.193189287421308 0.668500999719201 GO:0120013 lipid transfer activity 3/443 65/18639 0.0461538461538462 1.94189963535336 0.200867642439384 0.668500999719201 GO:0043015 gamma-tubulin binding 2/443 35/18639 0.0571428571428571 2.40425669138987 0.20187852965987 0.668500999719201 GO:0015399 primary active transmembrane transporter activity 6/443 166/18639 0.036144578313253 1.52076477467432 0.203669341970956 0.668500999719201 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.668500999719201 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.668500999719201 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.668500999719201 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.668500999719201 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/443 36/18639 0.0555555555555556 2.33747178329571 0.210611304928415 0.668500999719201 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/443 67/18639 0.0447761194029851 1.88393248205923 0.213192970782207 0.668500999719201 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0004935 adrenergic receptor activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0005131 growth hormone receptor binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0005522 profilin binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0008190 eukaryotic initiation factor 4E binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0015279 store-operated calcium channel activity 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0031720 haptoglobin binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0031996 thioesterase binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0032356 oxidized DNA binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0035374 chondroitin sulfate binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0043422 protein kinase B binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0051880 G-quadruplex DNA binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0070513 death domain binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0098505 G-rich strand telomeric DNA binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:1905394 retromer complex binding 1/443 10/18639 0.1 4.20744920993228 0.21384593871407 0.668500999719201 GO:0030551 cyclic nucleotide binding 2/443 37/18639 0.0540540540540541 2.27429687023366 0.219380655370177 0.679619150981206 GO:0008238 exopeptidase activity 4/443 102/18639 0.0392156862745098 1.64998008232638 0.224539171732237 0.679619150981206 GO:0051015 actin filament binding 7/443 209/18639 0.0334928229665072 1.40919351528832 0.230365852031346 0.679619150981206 GO:0003953 NAD+ nucleosidase activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0005114 type II transforming growth factor beta receptor binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0010854 adenylate cyclase regulator activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0015217 ADP transmembrane transporter activity 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0019215 intermediate filament binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0032050 clathrin heavy chain binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0048185 activin binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0050998 nitric-oxide synthase binding 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/443 11/18639 0.0909090909090909 3.82495382721116 0.23254078272876 0.679619150981206 GO:0070851 growth factor receptor binding 5/443 139/18639 0.0359712230215827 1.51347093882456 0.236033839982274 0.679619150981206 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/443 39/18639 0.0512820512820513 2.15766626150373 0.237002763563723 0.679619150981206 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/443 39/18639 0.0512820512820513 2.15766626150373 0.237002763563723 0.679619150981206 GO:0019207 kinase regulator activity 9/443 287/18639 0.0313588850174216 1.31940915990908 0.244905429547754 0.679619150981206 GO:0004177 aminopeptidase activity 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.679619150981206 GO:0015036 disulfide oxidoreductase activity 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.679619150981206 GO:0071949 FAD binding 2/443 40/18639 0.05 2.10372460496614 0.245843087643748 0.679619150981206 GO:0005165 neurotrophin receptor binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.679619150981206 GO:0034452 dynactin binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.679619150981206 GO:0035497 cAMP response element binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.679619150981206 GO:0043047 single-stranded telomeric DNA binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.679619150981206 GO:0045295 gamma-catenin binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.679619150981206 GO:0070008 serine-type exopeptidase activity 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.679619150981206 GO:0070679 inositol 1,4,5 trisphosphate binding 1/443 12/18639 0.0833333333333333 3.50620767494357 0.250792040687272 0.679619150981206 GO:0001530 lipopolysaccharide binding 2/443 41/18639 0.0487804878048781 2.05241424874745 0.254695099518945 0.679619150981206 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/443 41/18639 0.0487804878048781 2.05241424874745 0.254695099518945 0.679619150981206 GO:0042287 MHC protein binding 2/443 41/18639 0.0487804878048781 2.05241424874745 0.254695099518945 0.679619150981206 GO:0003779 actin binding 13/443 443/18639 0.0293453724604966 1.23469164174085 0.257288275691685 0.679619150981206 GO:0019887 protein kinase regulator activity 8/443 255/18639 0.0313725490196078 1.31998406586111 0.261893530438089 0.679619150981206 GO:0016859 cis-trans isomerase activity 2/443 42/18639 0.0476190476190476 2.0035472428249 0.263553263252055 0.679619150981206 GO:0048487 beta-tubulin binding 2/443 42/18639 0.0476190476190476 2.0035472428249 0.263553263252055 0.679619150981206 GO:0003725 double-stranded RNA binding 3/443 75/18639 0.04 1.68297968397291 0.263862008222651 0.679619150981206 GO:0003713 transcription coactivator activity 8/443 256/18639 0.03125 1.31482787810384 0.265254089865751 0.679619150981206 GO:0004222 metalloendopeptidase activity 4/443 110/18639 0.0363636363636364 1.52998153088447 0.265840031335655 0.679619150981206 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0004465 lipoprotein lipase activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0004535 poly(A)-specific ribonuclease activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0008035 high-density lipoprotein particle binding 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0008253 5'-nucleotidase activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0035325 Toll-like receptor binding 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0070123 transforming growth factor beta receptor activity, type III 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0140666 annealing activity 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:1901338 catecholamine binding 1/443 13/18639 0.0769230769230769 3.2364993922556 0.268610214627012 0.679619150981206 GO:0017022 myosin binding 3/443 76/18639 0.0394736842105263 1.66083521444695 0.270308751133859 0.679619150981206 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/443 43/18639 0.0465116279069767 1.95695312089873 0.272412298306241 0.679619150981206 GO:0008200 ion channel inhibitor activity 2/443 43/18639 0.0465116279069767 1.95695312089873 0.272412298306241 0.679619150981206 GO:0001046 core promoter sequence-specific DNA binding 2/443 44/18639 0.0454545454545455 1.91247691360558 0.281267170578537 0.679619150981206 GO:0001223 transcription coactivator binding 2/443 44/18639 0.0454545454545455 1.91247691360558 0.281267170578537 0.679619150981206 GO:0003954 NADH dehydrogenase activity 2/443 44/18639 0.0454545454545455 1.91247691360558 0.281267170578537 0.679619150981206 GO:0016248 channel inhibitor activity 2/443 44/18639 0.0454545454545455 1.91247691360558 0.281267170578537 0.679619150981206 GO:0019205 nucleobase-containing compound kinase activity 2/443 44/18639 0.0454545454545455 1.91247691360558 0.281267170578537 0.679619150981206 GO:0004065 arylsulfatase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0005344 oxygen carrier activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0005347 ATP transmembrane transporter activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0008195 phosphatidate phosphatase activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0008331 high voltage-gated calcium channel activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0016530 metallochaperone activity 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0031404 chloride ion binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0043176 amine binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0098847 sequence-specific single stranded DNA binding 1/443 14/18639 0.0714285714285714 3.00532086423734 0.286005558496884 0.679619150981206 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/443 45/18639 0.0444444444444444 1.86997742663657 0.290113083713695 0.679619150981206 GO:0042605 peptide antigen binding 2/443 45/18639 0.0444444444444444 1.86997742663657 0.290113083713695 0.679619150981206 GO:0141110 transporter inhibitor activity 2/443 45/18639 0.0444444444444444 1.86997742663657 0.290113083713695 0.679619150981206 GO:0000510 H3-H4 histone complex chaperone activity 5/443 151/18639 0.033112582781457 1.39319510262658 0.29013181115466 0.679619150981206 GO:0140584 chromatin extrusion motor activity 5/443 151/18639 0.033112582781457 1.39319510262658 0.29013181115466 0.679619150981206 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/443 151/18639 0.033112582781457 1.39319510262658 0.29013181115466 0.679619150981206 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/443 151/18639 0.033112582781457 1.39319510262658 0.29013181115466 0.679619150981206 GO:0001221 transcription coregulator binding 4/443 115/18639 0.0347826086956522 1.46346059475905 0.292322965386807 0.679619150981206 GO:0035401 histone H3Y41 kinase activity 4/443 115/18639 0.0347826086956522 1.46346059475905 0.292322965386807 0.679619150981206 GO:0140801 histone H2AXY142 kinase activity 4/443 115/18639 0.0347826086956522 1.46346059475905 0.292322965386807 0.679619150981206 GO:0015616 DNA translocase activity 5/443 152/18639 0.0328947368421053 1.38402934537246 0.294745203021893 0.679619150981206 GO:0140674 ATP-dependent histone chaperone activity 5/443 152/18639 0.0328947368421053 1.38402934537246 0.294745203021893 0.679619150981206 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/443 46/18639 0.0434782608695652 1.82932574344882 0.298945470690206 0.679619150981206 GO:0030291 protein serine/threonine kinase inhibitor activity 2/443 46/18639 0.0434782608695652 1.82932574344882 0.298945470690206 0.679619150981206 GO:0061775 cohesin loader activity 5/443 153/18639 0.0326797385620915 1.37498340193865 0.299371025071929 0.679619150981206 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.679619150981206 GO:0005523 tropomyosin binding 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.679619150981206 GO:0008252 nucleotidase activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.679619150981206 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.679619150981206 GO:0031005 filamin binding 1/443 15/18639 0.0666666666666667 2.80496613995485 0.302988084004851 0.679619150981206 GO:0005504 fatty acid binding 2/443 47/18639 0.0425531914893617 1.79040391912012 0.307759985670503 0.679619150981206 GO:0004386 helicase activity 5/443 155/18639 0.032258064516129 1.35724168062332 0.308656797218174 0.679619150981206 GO:0030165 PDZ domain binding 3/443 83/18639 0.036144578313253 1.52076477467432 0.315798147074047 0.679619150981206 GO:0140693 molecular condensate scaffold activity 2/443 48/18639 0.0416666666666667 1.75310383747178 0.316552496107608 0.679619150981206 GO:0004708 MAP kinase kinase activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0022841 potassium ion leak channel activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0034450 ubiquitin-ubiquitin ligase activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0043023 ribosomal large subunit binding 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0140328 floppase activity 1/443 16/18639 0.0625 2.62965575620767 0.319567566327974 0.679619150981206 GO:0140658 ATP-dependent chromatin remodeler activity 5/443 158/18639 0.0316455696202532 1.33147126896591 0.322659044712282 0.679619150981206 GO:0005004 GPI-linked ephrin receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0005008 hepatocyte growth factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0005009 insulin receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0005011 macrophage colony-stimulating factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0005020 stem cell factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0008288 boss receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0036332 placental growth factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0038062 protein tyrosine kinase collagen receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0060175 brain-derived neurotrophic factor receptor activity 2/443 49/18639 0.0408163265306122 1.71732620813562 0.325319075100654 0.679619150981206 GO:0003689 DNA clamp loader activity 5/443 160/18639 0.03125 1.31482787810384 0.332033937899332 0.679619150981206 GO:0005006 epidermal growth factor receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.679619150981206 GO:0005007 fibroblast growth factor receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.679619150981206 GO:0005017 platelet-derived growth factor receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.679619150981206 GO:0005019 platelet-derived growth factor beta-receptor activity 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.679619150981206 GO:0048020 CCR chemokine receptor binding 2/443 50/18639 0.04 1.68297968397291 0.334055993991965 0.679619150981206 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/443 86/18639 0.0348837209302326 1.46771484067405 0.335373119409106 0.679619150981206 GO:0004550 nucleoside diphosphate kinase activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0005092 GDP-dissociation inhibitor activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0008429 phosphatidylethanolamine binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0008484 sulfuric ester hydrolase activity 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0036041 long-chain fatty acid binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0070403 NAD+ binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0070492 oligosaccharide binding 1/443 17/18639 0.0588235294117647 2.47497012348958 0.335753549688158 0.679619150981206 GO:0008081 phosphoric diester hydrolase activity 3/443 87/18639 0.0344827586206897 1.45084455514906 0.341894426865051 0.679619150981206 GO:0005010 insulin-like growth factor receptor activity 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.679619150981206 GO:0005021 vascular endothelial growth factor receptor activity 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.679619150981206 GO:0005030 neurotrophin receptor activity 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.679619150981206 GO:0030544 Hsp70 protein binding 2/443 51/18639 0.0392156862745098 1.64998008232638 0.342759715198576 0.679619150981206 GO:0140713 histone chaperone activity 5/443 164/18639 0.0304878048780488 1.28275890546716 0.350852702623783 0.679619150981206 GO:0030159 signaling receptor complex adaptor activity 2/443 52/18639 0.0384615384615385 1.6182496961278 0.351426885271263 0.679619150981206 GO:0004706 JUN kinase kinase kinase activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:0004970 glutamate-gated receptor activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:0008525 phosphatidylcholine transporter activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:0031690 adrenergic receptor binding 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:0035615 clathrin adaptor activity 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:0070064 proline-rich region binding 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:1990381 ubiquitin-specific protease binding 1/443 18/18639 0.0555555555555556 2.33747178329571 0.351555352796747 0.679619150981206 GO:0003727 single-stranded RNA binding 3/443 89/18639 0.0337078651685393 1.41824130671875 0.354920706336064 0.679619150981206 GO:0005003 ephrin receptor activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.679619150981206 GO:0005005 transmembrane-ephrin receptor activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.679619150981206 GO:0005246 calcium channel regulator activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.679619150981206 GO:0005544 calcium-dependent phospholipid binding 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.679619150981206 GO:0016860 intramolecular oxidoreductase activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.679619150981206 GO:0038064 collagen receptor activity 2/443 53/18639 0.0377358490566038 1.58771668299331 0.360054328174354 0.679619150981206 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0022840 leak channel activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0022842 narrow pore channel activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0034987 immunoglobulin receptor binding 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0042577 lipid phosphatase activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0046624 sphingolipid transporter activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0050145 nucleoside monophosphate kinase activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0097001 ceramide binding 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0140036 ubiquitin-modified protein reader activity 1/443 19/18639 0.0526315789473684 2.21444695259594 0.366982074171058 0.679619150981206 GO:0072341 modified amino acid binding 3/443 91/18639 0.032967032967033 1.38707116810954 0.367913792519129 0.679619150981206 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/443 54/18639 0.037037037037037 1.55831452219714 0.368639038779792 0.679619150981206 GO:0050661 NADP binding 2/443 54/18639 0.037037037037037 1.55831452219714 0.368639038779792 0.679619150981206 GO:0140463 chromatin-protein adaptor activity 2/443 54/18639 0.037037037037037 1.55831452219714 0.368639038779792 0.679619150981206 GO:0005516 calmodulin binding 6/443 207/18639 0.0289855072463768 1.21955049563254 0.369694176183965 0.679821260041613 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/443 130/18639 0.0307692307692308 1.29459975690224 0.373152857744004 0.684430879382497 GO:0140104 molecular carrier activity 7/443 249/18639 0.0281124497991968 1.18281704696891 0.380255445632143 0.688442675381668 GO:0000339 RNA cap binding 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.688442675381668 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.688442675381668 GO:0010851 cyclase regulator activity 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.688442675381668 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.688442675381668 GO:0030627 pre-mRNA 5'-splice site binding 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.688442675381668 GO:0030742 GTP-dependent protein binding 1/443 20/18639 0.05 2.10372460496614 0.382042597325849 0.688442675381668 GO:0005179 hormone activity 4/443 132/18639 0.0303030303030303 1.27498460907039 0.383947206796267 0.69014510421629 GO:0003712 transcription coregulator activity 13/443 495/18639 0.0262626262626263 1.10498666119434 0.396419704375815 0.700884725825254 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.700884725825254 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.700884725825254 GO:0005123 death receptor binding 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.700884725825254 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.700884725825254 GO:0072542 protein phosphatase activator activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.700884725825254 GO:0140312 cargo adaptor activity 1/443 21/18639 0.0476190476190476 2.0035472428249 0.396745595842668 0.700884725825254 GO:0003823 antigen binding 5/443 174/18639 0.028735632183908 1.20903712929089 0.398032571471681 0.701434850216026 GO:0004896 cytokine receptor activity 3/443 96/18639 0.03125 1.31482787810384 0.40016724570595 0.703472493062538 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/443 58/18639 0.0344827586206897 1.45084455514906 0.402496090340671 0.705840704768153 GO:0001664 G protein-coupled receptor binding 8/443 297/18639 0.0269360269360269 1.13331965250701 0.410201728370861 0.710530211663537 GO:0070063 RNA polymerase binding 2/443 59/18639 0.0338983050847458 1.42625396946857 0.410827614570766 0.710530211663537 GO:0008970 phospholipase A1 activity 1/443 22/18639 0.0454545454545455 1.91247691360558 0.411099538319932 0.710530211663537 GO:0031683 G-protein beta/gamma-subunit complex binding 1/443 22/18639 0.0454545454545455 1.91247691360558 0.411099538319932 0.710530211663537 GO:0061133 endopeptidase activator activity 1/443 22/18639 0.0454545454545455 1.91247691360558 0.411099538319932 0.710530211663537 GO:0140035 ubiquitin-like protein reader activity 1/443 22/18639 0.0454545454545455 1.91247691360558 0.411099538319932 0.710530211663537 GO:0005319 lipid transporter activity 5/443 178/18639 0.0280898876404494 1.18186775559895 0.416843027326075 0.71503190157725 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/443 60/18639 0.0333333333333333 1.40248306997743 0.419101625894187 0.71503190157725 GO:0000295 adenine nucleotide transmembrane transporter activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0005212 structural constituent of eye lens 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0016493 C-C chemokine receptor activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0031681 G-protein beta-subunit binding 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0042171 lysophosphatidic acid acyltransferase activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0071617 lysophospholipid acyltransferase activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0099186 structural constituent of postsynapse 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/443 23/18639 0.0434782608695652 1.82932574344882 0.425112693206556 0.71503190157725 GO:0043130 ubiquitin binding 3/443 100/18639 0.03 1.26223476297968 0.425637905250435 0.71503190157725 GO:0004713 protein tyrosine kinase activity 4/443 140/18639 0.0285714285714286 1.20212834569494 0.426832101882243 0.715366622968141 GO:0004806 triacylglycerol lipase activity 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.725269570120022 GO:0005540 hyaluronic acid binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.725269570120022 GO:0015295 solute:proton symporter activity 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.725269570120022 GO:0019957 C-C chemokine binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.725269570120022 GO:0030215 semaphorin receptor binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.725269570120022 GO:0030552 cAMP binding 1/443 24/18639 0.0416666666666667 1.75310383747178 0.438793133521849 0.725269570120022 GO:1901981 phosphatidylinositol phosphate binding 5/443 185/18639 0.027027027027027 1.13714843511683 0.449507283679685 0.737176746287696 GO:0000030 mannosyltransferase activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.737176746287696 GO:0004709 MAP kinase kinase kinase activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.737176746287696 GO:0008139 nuclear localization sequence binding 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.737176746287696 GO:0019211 phosphatase activator activity 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.737176746287696 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/443 25/18639 0.04 1.68297968397291 0.452148741464359 0.737176746287696 GO:0140597 protein carrier chaperone 5/443 188/18639 0.0265957446808511 1.11900244945007 0.463367103617242 0.737185128480858 GO:0001637 G protein-coupled chemoattractant receptor activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0004435 phosphatidylinositol phospholipase C activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0004950 chemokine receptor activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0005112 Notch binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0005160 transforming growth factor beta receptor binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0008066 glutamate receptor activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0008157 protein phosphatase 1 binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0015216 purine nucleotide transmembrane transporter activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0019865 immunoglobulin binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0043548 phosphatidylinositol 3-kinase binding 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0070006 metalloaminopeptidase activity 1/443 26/18639 0.0384615384615385 1.6182496961278 0.465187212912263 0.737185128480858 GO:0005096 GTPase activator activity 7/443 271/18639 0.025830258302583 1.0867949988755 0.465482681961488 0.737185128480858 GO:0016500 protein-hormone receptor activity 2/443 67/18639 0.0298507462686567 1.25595498803949 0.475258767830061 0.743769801833422 GO:0001671 ATPase activator activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.743769801833422 GO:0008320 protein transmembrane transporter activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.743769801833422 GO:0008395 steroid hydroxylase activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.743769801833422 GO:0015252 proton channel activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.743769801833422 GO:0023026 MHC class II protein complex binding 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.743769801833422 GO:0035255 ionotropic glutamate receptor binding 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.743769801833422 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/443 27/18639 0.037037037037037 1.55831452219714 0.477916061817859 0.743769801833422 GO:0005548 phospholipid transporter activity 2/443 68/18639 0.0294117647058824 1.23748506174479 0.483011584005396 0.746941413166361 GO:0030145 manganese ion binding 2/443 68/18639 0.0294117647058824 1.23748506174479 0.483011584005396 0.746941413166361 GO:0005242 inward rectifier potassium channel activity 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0045499 chemorepellent activity 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0046625 sphingolipid binding 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0046875 ephrin receptor binding 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0050698 proteoglycan sulfotransferase activity 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0051019 mitogen-activated protein kinase binding 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0051537 2 iron, 2 sulfur cluster binding 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0097718 disordered domain specific binding 1/443 28/18639 0.0357142857142857 1.50266043211867 0.49034262449864 0.746941413166361 GO:0003785 actin monomer binding 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.754235598939213 GO:0004629 phospholipase C activity 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.754235598939213 GO:0035250 UDP-galactosyltransferase activity 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.754235598939213 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.754235598939213 GO:0051861 glycolipid binding 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.754235598939213 GO:0099604 ligand-gated calcium channel activity 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.754235598939213 GO:0106222 lncRNA binding 1/443 29/18639 0.0344827586206897 1.45084455514906 0.502474063827376 0.754235598939213 GO:0140299 molecular sensor activity 2/443 71/18639 0.028169014084507 1.1851969605443 0.505839279389523 0.757705087252223 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.762462250349811 GO:0015215 nucleotide transmembrane transporter activity 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.762462250349811 GO:0031210 phosphatidylcholine binding 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.762462250349811 GO:0048019 receptor antagonist activity 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.762462250349811 GO:0098918 structural constituent of synapse 1/443 30/18639 0.0333333333333333 1.40248306997743 0.514317373323586 0.762462250349811 GO:0017124 SH3 domain binding 3/443 115/18639 0.0260869565217391 1.09759544606929 0.517166739228325 0.765108817911864 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/443 31/18639 0.032258064516129 1.35724168062332 0.525879381148706 0.774809989848195 GO:0016411 acylglycerol O-acyltransferase activity 1/443 31/18639 0.032258064516129 1.35724168062332 0.525879381148706 0.774809989848195 GO:0099106 ion channel regulator activity 4/443 160/18639 0.025 1.05186230248307 0.529754461171937 0.778923226140332 GO:0019003 GDP binding 2/443 75/18639 0.0266666666666667 1.12198645598194 0.535239186008723 0.785005886445502 GO:0008378 galactosyltransferase activity 1/443 32/18639 0.03125 1.31482787810384 0.537166754007214 0.785005886445502 GO:0022884 macromolecule transmembrane transporter activity 1/443 32/18639 0.03125 1.31482787810384 0.537166754007214 0.785005886445502 GO:0051536 iron-sulfur cluster binding 2/443 76/18639 0.0263157894736842 1.10722347629797 0.542399468032368 0.7910450659539 GO:0032182 ubiquitin-like protein binding 3/443 120/18639 0.025 1.05186230248307 0.545912132111446 0.794556321838319 GO:0019956 chemokine binding 1/443 33/18639 0.0303030303030303 1.27498460907039 0.548186000955932 0.794648658643781 GO:0071889 14-3-3 protein binding 1/443 33/18639 0.0303030303030303 1.27498460907039 0.548186000955932 0.794648658643781 GO:0051540 metal cluster binding 2/443 77/18639 0.025974025974026 1.09284395063176 0.549482846037554 0.79492588792958 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/443 122/18639 0.0245901639344262 1.03461865818007 0.557127907394828 0.803760720103807 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/443 34/18639 0.0294117647058824 1.23748506174479 0.558943477123649 0.803760720103807 GO:0051427 hormone receptor binding 1/443 34/18639 0.0294117647058824 1.23748506174479 0.558943477123649 0.803760720103807 GO:0008094 ATP-dependent activity, acting on DNA 5/443 210/18639 0.0238095238095238 1.00177362141245 0.561025553491849 0.805144457007264 GO:0033293 monocarboxylic acid binding 2/443 79/18639 0.0253164556962025 1.06517701517273 0.563417366564896 0.806966307888766 GO:0016247 channel regulator activity 4/443 168/18639 0.0238095238095238 1.00177362141245 0.568354064439061 0.810321383485364 GO:0000175 3'-5'-RNA exonuclease activity 1/443 35/18639 0.0285714285714286 1.20212834569494 0.569445387343171 0.810321383485364 GO:0005154 epidermal growth factor receptor binding 1/443 35/18639 0.0285714285714286 1.20212834569494 0.569445387343171 0.810321383485364 GO:0000049 tRNA binding 2/443 80/18639 0.025 1.05186230248307 0.57026789992155 0.810321383485364 GO:0001618 virus receptor activity 2/443 81/18639 0.0246913580246914 1.03887634813143 0.577040305590823 0.815660882177641 GO:0141108 transporter regulator activity 4/443 170/18639 0.0235294117647059 0.989988049395831 0.57772691221479 0.815660882177641 GO:0000993 RNA polymerase II complex binding 1/443 36/18639 0.0277777777777778 1.16873589164786 0.579697789697879 0.815660882177641 GO:0004033 aldo-keto reductase (NADPH) activity 1/443 36/18639 0.0277777777777778 1.16873589164786 0.579697789697879 0.815660882177641 GO:0004190 aspartic-type endopeptidase activity 1/443 36/18639 0.0277777777777778 1.16873589164786 0.579697789697879 0.815660882177641 GO:0140272 exogenous protein binding 2/443 82/18639 0.024390243902439 1.02620712437373 0.583734419688738 0.819736421398833 GO:0023023 MHC protein complex binding 1/443 37/18639 0.027027027027027 1.13714843511683 0.589706598984759 0.823370396595609 GO:0070001 aspartic-type peptidase activity 1/443 37/18639 0.027027027027027 1.13714843511683 0.589706598984759 0.823370396595609 GO:0031490 chromatin DNA binding 3/443 128/18639 0.0234375 0.986120908577878 0.589757655419664 0.823370396595609 GO:0051117 ATPase binding 2/443 84/18639 0.0238095238095238 1.00177362141245 0.596887374237654 0.827302086907801 GO:0000146 microfilament motor activity 1/443 38/18639 0.0263157894736842 1.10722347629797 0.599477590095917 0.827302086907801 GO:0005501 retinoid binding 1/443 38/18639 0.0263157894736842 1.10722347629797 0.599477590095917 0.827302086907801 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/443 38/18639 0.0263157894736842 1.10722347629797 0.599477590095917 0.827302086907801 GO:0019840 isoprenoid binding 1/443 38/18639 0.0263157894736842 1.10722347629797 0.599477590095917 0.827302086907801 GO:0042162 telomeric DNA binding 1/443 38/18639 0.0263157894736842 1.10722347629797 0.599477590095917 0.827302086907801 GO:0005262 calcium channel activity 3/443 131/18639 0.0229007633587786 0.963537987007392 0.605481929368017 0.833987561715718 GO:0000217 DNA secondary structure binding 1/443 39/18639 0.0256410256410256 1.07883313075187 0.609016401320448 0.834687782995848 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/443 39/18639 0.0256410256410256 1.07883313075187 0.609016401320448 0.834687782995848 GO:0050660 flavin adenine dinucleotide binding 2/443 86/18639 0.0232558139534884 0.978476560449367 0.609726446461596 0.834687782995848 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/443 132/18639 0.0227272727272727 0.956238456802791 0.610633899660384 0.834687782995848 GO:0030695 GTPase regulator activity 11/443 489/18639 0.0224948875255624 0.946460967469429 0.616528786564921 0.840038152474343 GO:0004532 RNA exonuclease activity 1/443 40/18639 0.025 1.05186230248307 0.618328537568569 0.840038152474343 GO:0050997 quaternary ammonium group binding 1/443 40/18639 0.025 1.05186230248307 0.618328537568569 0.840038152474343 GO:0060589 nucleoside-triphosphatase regulator activity 11/443 490/18639 0.0224489795918367 0.944529414474593 0.619221447581922 0.840038152474343 GO:0051087 protein-folding chaperone binding 3/443 134/18639 0.0223880597014925 0.941966241029615 0.620802312072552 0.840136141115773 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/443 88/18639 0.0227272727272727 0.956238456802791 0.622252039249055 0.840136141115773 GO:0016853 isomerase activity 4/443 180/18639 0.0222222222222222 0.934988713318284 0.622799114345907 0.840136141115773 GO:0008227 G protein-coupled amine receptor activity 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.843204728150921 GO:0140318 protein transporter activity 1/443 41/18639 0.024390243902439 1.02620712437373 0.627419373519809 0.843204728150921 GO:0016922 nuclear receptor binding 3/443 137/18639 0.0218978102189781 0.921339243050864 0.635713464813617 0.848785711809266 GO:0004520 DNA endonuclease activity 1/443 42/18639 0.0238095238095238 1.00177362141245 0.636294156697072 0.848785711809266 GO:0043175 RNA polymerase core enzyme binding 1/443 42/18639 0.0238095238095238 1.00177362141245 0.636294156697072 0.848785711809266 GO:0051879 Hsp90 protein binding 1/443 42/18639 0.0238095238095238 1.00177362141245 0.636294156697072 0.848785711809266 GO:0005085 guanyl-nucleotide exchange factor activity 5/443 230/18639 0.0217391304347826 0.914662871724409 0.641437957561263 0.854062762012126 GO:0005245 voltage-gated calcium channel activity 1/443 43/18639 0.0232558139534884 0.978476560449367 0.644958010468282 0.855580829385046 GO:0048156 tau protein binding 1/443 43/18639 0.0232558139534884 0.978476560449367 0.644958010468282 0.855580829385046 GO:0051219 phosphoprotein binding 2/443 93/18639 0.021505376344086 0.904827787082211 0.652202921229179 0.86359834321138 GO:0016410 N-acyltransferase activity 2/443 94/18639 0.0212765957446809 0.89520195956006 0.65796140244835 0.868026143780483 GO:0042562 hormone binding 2/443 94/18639 0.0212765957446809 0.89520195956006 0.65796140244835 0.868026143780483 GO:0140303 intramembrane lipid transporter activity 1/443 45/18639 0.0222222222222222 0.934988713318284 0.661672820006065 0.871323731839489 GO:0004180 carboxypeptidase activity 1/443 46/18639 0.0217391304347826 0.914662871724409 0.66973342776864 0.878719588623453 GO:0030276 clathrin binding 1/443 46/18639 0.0217391304347826 0.914662871724409 0.66973342776864 0.878719588623453 GO:0008194 UDP-glycosyltransferase activity 3/443 145/18639 0.0206896551724138 0.870506733089437 0.673452658300261 0.881989911325842 GO:0001784 phosphotyrosine residue binding 1/443 47/18639 0.0212765957446809 0.89520195956006 0.677602415640338 0.884203515145923 GO:0140359 ABC-type transporter activity 1/443 47/18639 0.0212765957446809 0.89520195956006 0.677602415640338 0.884203515145923 GO:0015085 calcium ion transmembrane transporter activity 3/443 147/18639 0.0204081632653061 0.858663104067812 0.682425693417276 0.888884191244604 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/443 48/18639 0.0208333333333333 0.876551918735892 0.685284328821886 0.889385257081112 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/443 48/18639 0.0208333333333333 0.876551918735892 0.685284328821886 0.889385257081112 GO:0140097 catalytic activity, acting on DNA 7/443 336/18639 0.0208333333333333 0.876551918735892 0.690032227044136 0.891075871113837 GO:0016758 hexosyltransferase activity 4/443 197/18639 0.0203045685279188 0.854304408108077 0.692114951559234 0.891075871113837 GO:0016763 pentosyltransferase activity 1/443 49/18639 0.0204081632653061 0.858663104067812 0.692783604941078 0.891075871113837 GO:0035254 glutamate receptor binding 1/443 49/18639 0.0204081632653061 0.858663104067812 0.692783604941078 0.891075871113837 GO:0060590 ATPase regulator activity 1/443 49/18639 0.0204081632653061 0.858663104067812 0.692783604941078 0.891075871113837 GO:0015631 tubulin binding 8/443 385/18639 0.0207792207792208 0.874275160505409 0.698890459473456 0.897281979626452 GO:0015605 organophosphate ester transmembrane transporter activity 1/443 50/18639 0.02 0.841489841986456 0.700104576593101 0.897281979626452 GO:0016829 lyase activity 4/443 200/18639 0.02 0.841489841986456 0.703358072634922 0.899847783317632 GO:0005048 signal sequence binding 1/443 51/18639 0.0196078431372549 0.824990041163192 0.707251473820991 0.901620229924278 GO:0005272 sodium channel activity 1/443 51/18639 0.0196078431372549 0.824990041163192 0.707251473820991 0.901620229924278 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/443 52/18639 0.0192307692307692 0.8091248480639 0.714228426537653 0.903410224552979 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 10/443 484/18639 0.0206611570247934 0.869307688002537 0.717728236192853 0.903410224552979 GO:0003714 transcription corepressor activity 4/443 204/18639 0.0196078431372549 0.824990041163192 0.717884037720281 0.903410224552979 GO:0140375 immune receptor activity 3/443 156/18639 0.0192307692307692 0.8091248480639 0.720532282031464 0.903410224552979 GO:0008146 sulfotransferase activity 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.903410224552979 GO:0051018 protein kinase A binding 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.903410224552979 GO:0140296 general transcription initiation factor binding 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.903410224552979 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.903410224552979 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/443 53/18639 0.0188679245283019 0.793858341496657 0.721039466890793 0.903410224552979 GO:0004497 monooxygenase activity 2/443 106/18639 0.0188679245283019 0.793858341496657 0.721220401798901 0.903410224552979 GO:0003925 G protein activity 1/443 54/18639 0.0185185185185185 0.77915726109857 0.727688531572133 0.908347316320075 GO:0017069 snRNA binding 1/443 54/18639 0.0185185185185185 0.77915726109857 0.727688531572133 0.908347316320075 GO:0001216 DNA-binding transcription activator activity 10/443 491/18639 0.0203665987780041 0.85691429937521 0.733974474973297 0.913229118995871 GO:0008374 O-acyltransferase activity 1/443 55/18639 0.0181818181818182 0.764990765442233 0.734179464072189 0.913229118995871 GO:0004620 phospholipase activity 2/443 109/18639 0.018348623853211 0.772009029345372 0.735409819052308 0.913229118995871 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/443 56/18639 0.0178571428571429 0.751330216059336 0.740516016881919 0.91798451058293 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/443 57/18639 0.0175438596491228 0.738148984198646 0.746701853642469 0.923332932628961 GO:0005543 phospholipid binding 10/443 497/18639 0.0201207243460765 0.846569257531646 0.747398841154458 0.923332932628961 GO:0008408 3'-5' exonuclease activity 1/443 58/18639 0.0172413793103448 0.725422277574531 0.752740551244255 0.928336974862126 GO:0015459 potassium channel regulator activity 1/443 59/18639 0.0169491525423729 0.713126984734285 0.758635601876557 0.930817402302465 GO:0031593 polyubiquitin modification-dependent protein binding 1/443 59/18639 0.0169491525423729 0.713126984734285 0.758635601876557 0.930817402302465 GO:0045309 protein phosphorylated amino acid binding 1/443 59/18639 0.0169491525423729 0.713126984734285 0.758635601876557 0.930817402302465 GO:0016757 glycosyltransferase activity 5/443 267/18639 0.0187265917602996 0.78791183706597 0.763917268587932 0.931519844755436 GO:0001098 basal transcription machinery binding 1/443 60/18639 0.0166666666666667 0.701241534988713 0.7643904150288 0.931519844755436 GO:0001099 basal RNA polymerase II transcription machinery binding 1/443 60/18639 0.0166666666666667 0.701241534988713 0.7643904150288 0.931519844755436 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/443 60/18639 0.0166666666666667 0.701241534988713 0.7643904150288 0.931519844755436 GO:0019905 syntaxin binding 1/443 61/18639 0.0163934426229508 0.689745772120046 0.770008319444659 0.936778310796463 GO:0016887 ATP hydrolysis activity 8/443 417/18639 0.0191846522781775 0.807184500706433 0.777925146613542 0.943577323480759 GO:0005507 copper ion binding 1/443 63/18639 0.0158730158730159 0.667849080941632 0.780846324716345 0.943577323480759 GO:0022824 transmitter-gated monoatomic ion channel activity 1/443 63/18639 0.0158730158730159 0.667849080941632 0.780846324716345 0.943577323480759 GO:0022835 transmitter-gated channel activity 1/443 63/18639 0.0158730158730159 0.667849080941632 0.780846324716345 0.943577323480759 GO:0004536 DNA nuclease activity 1/443 64/18639 0.015625 0.657413939051919 0.786072696279149 0.948299108430719 GO:0008235 metalloexopeptidase activity 1/443 66/18639 0.0151515151515152 0.637492304535194 0.796155300974833 0.95885370418912 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/443 181/18639 0.0165745856353591 0.697367272364466 0.807736670510789 0.966166473704328 GO:0004519 endonuclease activity 2/443 127/18639 0.015748031496063 0.662590426760989 0.808166777026335 0.966166473704328 GO:0035091 phosphatidylinositol binding 5/443 284/18639 0.0176056338028169 0.74074810034019 0.808414969900078 0.966166473704328 GO:0002039 p53 binding 1/443 69/18639 0.0144927536231884 0.609775247816272 0.810397113822214 0.966166473704328 GO:0008080 N-acetyltransferase activity 1/443 69/18639 0.0144927536231884 0.609775247816272 0.810397113822214 0.966166473704328 GO:0098960 postsynaptic neurotransmitter receptor activity 1/443 69/18639 0.0144927536231884 0.609775247816272 0.810397113822214 0.966166473704328 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/443 128/18639 0.015625 0.657413939051919 0.811633588480409 0.966166473704328 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/443 70/18639 0.0142857142857143 0.601064172847468 0.814920219830655 0.96687729052515 GO:0016782 transferase activity, transferring sulphur-containing groups 1/443 70/18639 0.0142857142857143 0.601064172847468 0.814920219830655 0.96687729052515 GO:0016298 lipase activity 2/443 130/18639 0.0153846153846154 0.64729987845112 0.818400070582015 0.969406343901926 GO:0031072 heat shock protein binding 2/443 131/18639 0.0152671755725191 0.642358658004928 0.821701127034945 0.971715642003496 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/443 73/18639 0.0136986301369863 0.576362905470175 0.82785372155775 0.975781681639381 GO:0043539 protein serine/threonine kinase activator activity 1/443 73/18639 0.0136986301369863 0.576362905470175 0.82785372155775 0.975781681639381 GO:0003678 DNA helicase activity 1/443 74/18639 0.0135135135135135 0.568574217558416 0.831961273068572 0.975824070695437 GO:0003684 damaged DNA binding 1/443 74/18639 0.0135135135135135 0.568574217558416 0.831961273068572 0.975824070695437 GO:0048029 monosaccharide binding 1/443 74/18639 0.0135135135135135 0.568574217558416 0.831961273068572 0.975824070695437 GO:0044183 protein folding chaperone 1/443 75/18639 0.0133333333333333 0.560993227990971 0.835971031001813 0.978930246401146 GO:0099094 ligand-gated monoatomic cation channel activity 2/443 136/18639 0.0147058823529412 0.618742530872394 0.837412123222861 0.979023279019898 GO:0042393 histone binding 4/443 247/18639 0.0161943319838057 0.681368293106442 0.841939314908988 0.982718128927861 GO:0022804 active transmembrane transporter activity 8/443 457/18639 0.0175054704595186 0.736533778543944 0.854010219119624 0.995191811259335 GO:0022843 voltage-gated monoatomic cation channel activity 2/443 143/18639 0.013986013986014 0.588454434955564 0.857307110234033 0.997417171938948 GO:0005254 chloride channel activity 1/443 83/18639 0.0120481927710843 0.506921591558106 0.864796061750636 0.997535710535067 GO:0042578 phosphoric ester hydrolase activity 6/443 363/18639 0.0165289256198347 0.69544615040203 0.865362864166095 0.997535710535067 GO:0004527 exonuclease activity 1/443 84/18639 0.0119047619047619 0.500886810706224 0.86802387726284 0.997535710535067 GO:0019209 kinase activator activity 2/443 148/18639 0.0135135135135135 0.568574217558416 0.870130225581198 0.997535710535067 GO:0003730 mRNA 3'-UTR binding 4/443 262/18639 0.0152671755725191 0.642358658004928 0.872796494410233 0.997535710535067 GO:0046982 protein heterodimerization activity 6/443 369/18639 0.016260162601626 0.684138082915818 0.875149097796386 0.997535710535067 GO:0004518 nuclease activity 3/443 209/18639 0.0143540669856459 0.60394007798071 0.877037023346673 0.997535710535067 GO:0052689 carboxylic ester hydrolase activity 1/443 92/18639 0.0108695652173913 0.457331435862204 0.891226541322321 0.997535710535067 GO:0008017 microtubule binding 4/443 276/18639 0.0144927536231884 0.609775247816272 0.8967720882442 0.997535710535067 GO:0140098 catalytic activity, acting on RNA 6/443 387/18639 0.0155038759689922 0.652317706966245 0.901002036440214 0.997535710535067 GO:0016407 acetyltransferase activity 1/443 96/18639 0.0104166666666667 0.438275959367946 0.901253212524807 0.997535710535067 GO:0030594 neurotransmitter receptor activity 1/443 97/18639 0.0103092783505155 0.433757650508482 0.903612314442054 0.997535710535067 GO:0005249 voltage-gated potassium channel activity 1/443 98/18639 0.0102040816326531 0.429331552033906 0.905915180621656 0.997535710535067 GO:0008170 N-methyltransferase activity 1/443 98/18639 0.0102040816326531 0.429331552033906 0.905915180621656 0.997535710535067 GO:0042626 ATPase-coupled transmembrane transporter activity 1/443 98/18639 0.0102040816326531 0.429331552033906 0.905915180621656 0.997535710535067 GO:0016874 ligase activity 2/443 167/18639 0.0119760479041916 0.503886132926022 0.909772735309804 0.997535710535067 GO:0005261 monoatomic cation channel activity 5/443 341/18639 0.0146627565982405 0.616928036646962 0.910884768058699 0.997535710535067 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/443 229/18639 0.0131004366812227 0.551194219641783 0.911988460639112 0.997535710535067 GO:0000287 magnesium ion binding 3/443 230/18639 0.0130434782608696 0.548797723034645 0.913473387028062 0.997535710535067 GO:0015171 amino acid transmembrane transporter activity 1/443 102/18639 0.00980392156862745 0.412495020581596 0.914590567777772 0.997535710535067 GO:0005253 monoatomic anion channel activity 1/443 103/18639 0.00970873786407767 0.408490214556532 0.916631695170255 0.997535710535067 GO:0005244 voltage-gated monoatomic ion channel activity 2/443 173/18639 0.0115606936416185 0.486410313286969 0.919728662703572 0.997535710535067 GO:0000149 SNARE binding 1/443 106/18639 0.00943396226415094 0.396929170748328 0.922467651907699 0.997535710535067 GO:0022832 voltage-gated channel activity 2/443 175/18639 0.0114285714285714 0.480851338277975 0.922811356588664 0.997535710535067 GO:0141003 histone H2AX kinase activity 5/443 354/18639 0.0141242937853107 0.594272487278571 0.926077394444068 0.997535710535067 GO:0004843 cysteine-type deubiquitinase activity 1/443 108/18639 0.00925925925925926 0.389578630549285 0.926130009142875 0.997535710535067 GO:0140996 histone H3 kinase activity 5/443 357/18639 0.0140056022408964 0.589278600830852 0.929239590263812 0.997535710535067 GO:0005549 odorant binding 1/443 111/18639 0.00900900900900901 0.379049478372277 0.931302425614548 0.997535710535067 GO:0035173 histone kinase activity 5/443 360/18639 0.0138888888888889 0.584367945823928 0.932281002931824 0.997535710535067 GO:0101005 deubiquitinase activity 1/443 115/18639 0.00869565217391304 0.365865148689763 0.937641186721136 0.997535710535067 GO:0015276 ligand-gated monoatomic ion channel activity 2/443 186/18639 0.010752688172043 0.452413893541105 0.937866418600594 0.997535710535067 GO:0031406 carboxylic acid binding 2/443 187/18639 0.0106951871657754 0.449994567907196 0.939087728010946 0.997535710535067 GO:0015294 solute:monoatomic cation symporter activity 1/443 116/18639 0.00862068965517241 0.362711138787265 0.939132492825786 0.997535710535067 GO:0022834 ligand-gated channel activity 2/443 188/18639 0.0106382978723404 0.44760097978003 0.940286257560647 0.997535710535067 GO:0046943 carboxylic acid transmembrane transporter activity 2/443 188/18639 0.0106382978723404 0.44760097978003 0.940286257560647 0.997535710535067 GO:0005342 organic acid transmembrane transporter activity 2/443 189/18639 0.0105820105820106 0.445232720627754 0.941462396944059 0.997535710535067 GO:0043177 organic acid binding 2/443 189/18639 0.0105820105820106 0.445232720627754 0.941462396944059 0.997535710535067 GO:0003697 single-stranded DNA binding 1/443 121/18639 0.00826446280991736 0.347723075201015 0.946071881692798 0.997535710535067 GO:0004540 RNA nuclease activity 1/443 121/18639 0.00826446280991736 0.347723075201015 0.946071881692798 0.997535710535067 GO:0015108 chloride transmembrane transporter activity 1/443 121/18639 0.00826446280991736 0.347723075201015 0.946071881692798 0.997535710535067 GO:0004674 protein serine/threonine kinase activity 6/443 433/18639 0.0138568129330254 0.583018366272371 0.947182345127955 0.997535710535067 GO:0008528 G protein-coupled peptide receptor activity 1/443 122/18639 0.00819672131147541 0.344872886060023 0.947361986261871 0.997535710535067 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/443 122/18639 0.00819672131147541 0.344872886060023 0.947361986261871 0.997535710535067 GO:0005267 potassium channel activity 1/443 124/18639 0.00806451612903226 0.339310420155829 0.949850544622658 0.997535710535067 GO:0019783 ubiquitin-like protein peptidase activity 1/443 127/18639 0.0078740157480315 0.331295213380494 0.953364997926382 0.997535710535067 GO:0042826 histone deacetylase binding 1/443 127/18639 0.0078740157480315 0.331295213380494 0.953364997926382 0.997535710535067 GO:0001653 peptide receptor activity 1/443 128/18639 0.0078125 0.328706969525959 0.95448099327635 0.997535710535067 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/443 268/18639 0.0111940298507463 0.470983120514807 0.95550059761245 0.997535710535067 GO:0008514 organic anion transmembrane transporter activity 3/443 269/18639 0.0111524163568773 0.469232253895793 0.956292017058723 0.997535710535067 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/443 130/18639 0.00769230769230769 0.32364993922556 0.956633676661846 0.997535710535067 GO:0005216 monoatomic ion channel activity 6/443 448/18639 0.0133928571428571 0.563497662044502 0.957394873152217 0.997535710535067 GO:0016791 phosphatase activity 3/443 273/18639 0.010989010989011 0.462357056036514 0.959327952887499 0.997535710535067 GO:0015297 antiporter activity 1/443 135/18639 0.00740740740740741 0.311662904439428 0.961581349884634 0.997535710535067 GO:0044325 transmembrane transporter binding 1/443 136/18639 0.00735294117647059 0.309371265436197 0.962501121933981 0.997535710535067 GO:0001217 DNA-binding transcription repressor activity 3/443 278/18639 0.0107913669064748 0.454041281647368 0.962845278409571 0.997535710535067 GO:0030295 protein kinase activator activity 1/443 139/18639 0.00719424460431655 0.302694187764912 0.965130691227438 0.997535710535067 GO:0140767 enzyme-substrate adaptor activity 1/443 139/18639 0.00719424460431655 0.302694187764912 0.965130691227438 0.997535710535067 GO:0061630 ubiquitin protein ligase activity 4/443 353/18639 0.0113314447592068 0.476764782995159 0.970046986689956 0.997535710535067 GO:0015293 symporter activity 1/443 146/18639 0.00684931506849315 0.288181452735088 0.970572841507243 0.997535710535067 GO:0045182 translation regulator activity 4/443 356/18639 0.0112359550561798 0.472747102239582 0.971531008160748 0.997535710535067 GO:0008509 monoatomic anion transmembrane transporter activity 1/443 149/18639 0.00671140939597315 0.282379141606193 0.972637478942532 0.997535710535067 GO:0106310 protein serine kinase activity 4/443 361/18639 0.0110803324099723 0.46619935844125 0.973852750162473 0.997535710535067 GO:0003774 cytoskeletal motor activity 1/443 153/18639 0.0065359477124183 0.274996680387731 0.975167235057713 0.997535710535067 GO:0061659 ubiquitin-like protein ligase activity 4/443 372/18639 0.010752688172043 0.452413893541105 0.978351067618618 0.997535710535067 GO:0015079 potassium ion transmembrane transporter activity 1/443 160/18639 0.00625 0.262965575620767 0.979045680348592 0.997535710535067 GO:0015081 sodium ion transmembrane transporter activity 1/443 164/18639 0.00609756097560976 0.256551781093432 0.980984088595345 0.997535710535067 GO:0015103 inorganic anion transmembrane transporter activity 1/443 165/18639 0.00606060606060606 0.254996921814078 0.981440058757849 0.997535710535067 GO:0022836 gated channel activity 3/443 318/18639 0.00943396226415094 0.396929170748328 0.982283116356664 0.997535710535067 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/443 167/18639 0.00598802395209581 0.251943066463011 0.982319531552051 0.997535710535067 GO:0140030 modification-dependent protein binding 1/443 173/18639 0.00578034682080925 0.243205156643484 0.984716197633386 0.997535710535067 GO:0008234 cysteine-type peptidase activity 1/443 187/18639 0.0053475935828877 0.224997283953598 0.989122269303003 0.997535710535067 GO:0015291 secondary active transmembrane transporter activity 2/443 287/18639 0.00696864111498258 0.293202035535351 0.992296248039256 0.997535710535067 GO:0016755 aminoacyltransferase activity 5/443 496/18639 0.0100806451612903 0.424138025194786 0.992346872378557 0.997535710535067 GO:0008168 methyltransferase activity 1/443 204/18639 0.00490196078431373 0.206247510290798 0.992804779596502 0.997535710535067 GO:0016741 transferase activity, transferring one-carbon groups 1/443 215/18639 0.00465116279069767 0.195695312089873 0.994494313328458 0.997535710535067 GO:0004842 ubiquitin-protein transferase activity 4/443 449/18639 0.0089086859688196 0.374828437410448 0.994537564385292 0.997535710535067 GO:0046873 metal ion transmembrane transporter activity 4/443 450/18639 0.00888888888888889 0.373995485327314 0.994637446282728 0.997535710535067 GO:0019787 ubiquitin-like protein transferase activity 4/443 479/18639 0.00835073068893528 0.35135275239518 0.996877389326267 0.997535710535067 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/443 243/18639 0.00411522633744856 0.173146058021905 0.997216255340537 0.997535710535067 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0004711 ribosomal protein S6 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0035175 histone H3S10 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0035979 histone H2AXS139 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0044022 histone H3S28 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0044023 histone H4S1 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0044024 histone H2AS1 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0044025 histone H2BS14 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0072354 histone H3T3 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0072371 histone H2AS121 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0140823 histone H2BS36 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0140855 histone H3S57 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0140995 histone H2A kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0140997 histone H4 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0140998 histone H2B kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:1990244 histone H2AT120 kinase activity 1/443 245/18639 0.00408163265306122 0.171732620813562 0.99734871707865 0.997535710535067 GO:0004677 DNA-dependent protein kinase activity 1/443 246/18639 0.0040650406504065 0.171034520728955 0.997412570418552 0.997535710535067 GO:0140857 histone H3T45 kinase activity 1/443 246/18639 0.0040650406504065 0.171034520728955 0.997412570418552 0.997535710535067 GO:0035402 histone H3T11 kinase activity 1/443 247/18639 0.00404858299595142 0.170342073276611 0.997474889306421 0.997535710535067 GO:0035403 histone H3T6 kinase activity 1/443 247/18639 0.00404858299595142 0.170342073276611 0.997474889306421 0.997535710535067 GO:0004679 AMP-activated protein kinase activity 1/443 248/18639 0.00403225806451613 0.169655210077915 0.997535710535067 0.997535710535067