ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	45/1191	175/18639	0.257142857142857	4.02425332853544	3.56235996151095e-16	3.98271843696924e-13
GO:0005201	extracellular matrix structural constituent	37/1191	168/18639	0.220238095238095	3.44669845268082	2.31335781952747e-11	1.29316702111585e-08
GO:0048407	platelet-derived growth factor binding	8/1191	11/18639	0.727272727272727	11.3817265857568	3.76859715882154e-08	1.40443054118749e-05
GO:0005518	collagen binding	19/1191	72/18639	0.263888888888889	4.12982787573468	7.98228168281211e-08	2.23104773034598e-05
GO:0019838	growth factor binding	26/1191	136/18639	0.191176470588235	2.99188768706475	4.2354074120462e-07	8.19890163187084e-05
GO:0019843	rRNA binding	17/1191	65/18639	0.261538461538462	4.09304398372408	4.40012609939401e-07	8.19890163187084e-05
GO:0005178	integrin binding	28/1191	161/18639	0.173913043478261	2.7217172270288	1.15620290398405e-06	0.000184662120950595
GO:0043021	ribonucleoprotein complex binding	29/1191	177/18639	0.163841807909605	2.56410365879691	2.62711293146956e-06	0.000367139032172871
GO:0001968	fibronectin binding	10/1191	30/18639	0.333333333333333	5.21662468513854	1.00955497677776e-05	0.00122811078402933
GO:0005539	glycosaminoglycan binding	34/1191	242/18639	0.140495867768595	2.19874263588484	1.25253995654235e-05	0.00122811078402933
GO:0008201	heparin binding	27/1191	172/18639	0.156976744186047	2.45666627614082	1.29454894906663e-05	0.00122811078402933
GO:0030020	extracellular matrix structural constituent conferring tensile strength	12/1191	44/18639	0.272727272727273	4.2681474696588	1.36577343135782e-05	0.00122811078402933
GO:1901681	sulfur compound binding	37/1191	275/18639	0.134545454545455	2.10561941836501	1.42803579538294e-05	0.00122811078402933
GO:0050840	extracellular matrix binding	15/1191	67/18639	0.223880597014925	3.50370314673484	1.641707336975e-05	0.00131102057338432
GO:0045296	cadherin binding	42/1191	334/18639	0.125748502994012	1.96794823451334	2.07051495423095e-05	0.00154322381255347
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	12/1191	54/18639	0.222222222222222	3.47774979009236	0.000122700477459117	0.0085736958624558
GO:0002020	protease binding	21/1191	136/18639	0.154411764705882	2.41652467032153	0.000145592426180083	0.00932908234582876
GO:0000339	RNA cap binding	7/1191	20/18639	0.35	5.47745591939547	0.000158308743315644	0.00932908234582876
GO:0015036	disulfide oxidoreductase activity	10/1191	40/18639	0.25	3.9124685138539	0.000158544333247537	0.00932908234582876
GO:0008135	translation factor activity, RNA binding	15/1191	83/18639	0.180722891566265	2.82829049194258	0.000220926616190766	0.0123497978450638
GO:0180051	translation factor activity	15/1191	84/18639	0.178571428571429	2.7946203670385	0.000253319418236477	0.0129679778273465
GO:0043022	ribosome binding	18/1191	112/18639	0.160714285714286	2.51515833033465	0.000255183821289467	0.0129679778273465
GO:0016504	peptidase activator activity	11/1191	57/18639	0.192982456140351	3.02015113350126	0.000840766540486004	0.0395977264429541
GO:0031994	insulin-like growth factor I binding	5/1191	13/18639	0.384615384615385	6.01918232900601	0.000881750406595821	0.0395977264429541
GO:0005520	insulin-like growth factor binding	6/1191	19/18639	0.315789473684211	4.94206549118388	0.000885458999171604	0.0395977264429541
GO:0070006	metalloaminopeptidase activity	7/1191	26/18639	0.269230769230769	4.2134276303042	0.000958067904325494	0.0411969198859962
GO:0050660	flavin adenine dinucleotide binding	14/1191	86/18639	0.162790697674419	2.54765391599789	0.00105046535796488	0.0434970470446198
GO:0015035	protein-disulfide reductase activity	8/1191	34/18639	0.235294117647059	3.68232330715662	0.00110605999291693	0.0441633954314689
GO:0003743	translation initiation factor activity	10/1191	51/18639	0.196078431372549	3.06860275596385	0.00126003897751445	0.0485766750641777
GO:0043236	laminin binding	7/1191	29/18639	0.241379310344828	3.77755580647963	0.00192139561009563	0.0715330018441988
GO:0043394	proteoglycan binding	8/1191	37/18639	0.216216216216216	3.3837565525223	0.00198347321750462	0.0715330018441988
GO:0001221	transcription coregulator binding	16/1191	115/18639	0.139130434782609	2.17737378162304	0.00263074897552716	0.0919117923324802
GO:0071949	FAD binding	8/1191	40/18639	0.2	3.12997481108312	0.00333360999871755	0.103937020519608
GO:0050431	transforming growth factor beta binding	6/1191	24/18639	0.25	3.9124685138539	0.00333692717752091	0.103937020519608
GO:0019001	guanyl nucleotide binding	40/1191	400/18639	0.1	1.56498740554156	0.0033468092475008	0.103937020519608
GO:0032561	guanyl ribonucleotide binding	40/1191	400/18639	0.1	1.56498740554156	0.0033468092475008	0.103937020519608
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/1191	11/18639	0.363636363636364	5.69086329287841	0.00380639262687429	0.115014782617445
GO:0046332	SMAD binding	12/1191	79/18639	0.151898734177215	2.37719605905047	0.00420983742826374	0.123857848547338
GO:0003746	translation elongation factor activity	5/1191	18/18639	0.277777777777778	4.34718723761545	0.00449055470274076	0.128729234811902
GO:0061134	peptidase regulator activity	25/1191	226/18639	0.110619469026549	1.73118075834244	0.0052783024680269	0.144260955351261
GO:0000340	RNA 7-methylguanosine cap binding	4/1191	12/18639	0.333333333333333	5.21662468513854	0.00542326588354857	0.144260955351261
GO:0043047	single-stranded telomeric DNA binding	4/1191	12/18639	0.333333333333333	5.21662468513854	0.00542326588354857	0.144260955351261
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	35/1191	349/18639	0.100286532951289	1.56947161014197	0.0055484982827408	0.144260955351261
GO:0019205	nucleobase-containing compound kinase activity	8/1191	44/18639	0.181818181818182	2.8454316464392	0.00613019157409107	0.155762594996223
GO:0001540	amyloid-beta binding	12/1191	83/18639	0.144578313253012	2.26263239355406	0.00630510218784014	0.156646761022339
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/1191	36/18639	0.194444444444444	3.04303106633081	0.00695745491948734	0.162050720833059
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/1191	36/18639	0.194444444444444	3.04303106633081	0.00695745491948734	0.162050720833059
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/1191	36/18639	0.194444444444444	3.04303106633081	0.00695745491948734	0.162050720833059
GO:0043024	ribosomal small subunit binding	5/1191	20/18639	0.25	3.9124685138539	0.00730508690241255	0.166675248099943
GO:0019208	phosphatase regulator activity	15/1191	117/18639	0.128205128205128	2.00639410966867	0.007586276766648	0.169629148502249
GO:0033218	amide binding	26/1191	247/18639	0.105263157894737	1.64735516372796	0.00851786207195277	0.18514066826367
GO:0019212	phosphatase inhibitor activity	9/1191	56/18639	0.160714285714286	2.51515833033465	0.00861119387272883	0.18514066826367
GO:0008191	metalloendopeptidase inhibitor activity	4/1191	14/18639	0.285714285714286	4.47139258726161	0.00989848218088863	0.204935242189509
GO:0098847	sequence-specific single stranded DNA binding	4/1191	14/18639	0.285714285714286	4.47139258726161	0.00989848218088863	0.204935242189509
GO:0051082	unfolded protein binding	15/1191	121/18639	0.12396694214876	1.94006703166309	0.0102471366681924	0.206717257981095
GO:1990841	promoter-specific chromatin binding	10/1191	68/18639	0.147058823529412	2.30145206697288	0.010769237040551	0.206717257981095
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/1191	39/18639	0.179487179487179	2.80895175353614	0.0108573254347885	0.206717257981095
GO:0016776	phosphotransferase activity, phosphate group as acceptor	7/1191	39/18639	0.179487179487179	2.80895175353614	0.0108573254347885	0.206717257981095
GO:0005525	GTP binding	36/1191	378/18639	0.0952380952380952	1.49046419575387	0.0109090502870166	0.206717257981095
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	5/1191	22/18639	0.227272727272727	3.556789558049	0.0111592900726238	0.207934771686556
GO:0001222	transcription corepressor binding	8/1191	49/18639	0.163265306122449	2.5550814784352	0.0117796770070524	0.215896375309584
GO:0070063	RNA polymerase binding	9/1191	59/18639	0.152542372881356	2.38726892370747	0.0120482307100553	0.217256805384546
GO:0004177	aminopeptidase activity	7/1191	40/18639	0.175	2.73872795969773	0.0124532650727429	0.219442604580533
GO:0000049	tRNA binding	11/1191	80/18639	0.1375	2.15185768261965	0.0125620095645385	0.219442604580533
GO:0001098	basal transcription machinery binding	9/1191	60/18639	0.15	2.34748110831234	0.0133943889604477	0.226892831178492
GO:0001099	basal RNA polymerase II transcription machinery binding	9/1191	60/18639	0.15	2.34748110831234	0.0133943889604477	0.226892831178492
GO:0003689	DNA clamp loader activity	18/1191	160/18639	0.1125	1.76061083123426	0.0138348906518305	0.230856832070844
GO:0019905	syntaxin binding	9/1191	61/18639	0.147540983606557	2.30899781145476	0.014848829773405	0.240036560037122
GO:0016859	cis-trans isomerase activity	7/1191	42/18639	0.166666666666667	2.60831234256927	0.0161396377522528	0.240036560037122
GO:0042056	chemoattractant activity	7/1191	42/18639	0.166666666666667	2.60831234256927	0.0161396377522528	0.240036560037122
GO:0048027	mRNA 5'-UTR binding	5/1191	24/18639	0.208333333333333	3.26039042821159	0.0162057285851608	0.240036560037122
GO:0015562	efflux transmembrane transporter activity	4/1191	16/18639	0.25	3.9124685138539	0.0162521628912715	0.240036560037122
GO:0000510	H3-H4 histone complex chaperone activity	17/1191	151/18639	0.112582781456954	1.76190635060971	0.0163173332404483	0.240036560037122
GO:0140584	chromatin extrusion motor activity	17/1191	151/18639	0.112582781456954	1.76190635060971	0.0163173332404483	0.240036560037122
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	17/1191	151/18639	0.112582781456954	1.76190635060971	0.0163173332404483	0.240036560037122
GO:0140849	ATP-dependent H2AZ histone chaperone activity	17/1191	151/18639	0.112582781456954	1.76190635060971	0.0163173332404483	0.240036560037122
GO:0140104	molecular carrier activity	25/1191	249/18639	0.100401606425703	1.57127249552366	0.0169073462190416	0.240681043098804
GO:0015616	DNA translocase activity	17/1191	152/18639	0.111842105263158	1.75031486146096	0.0173171721235476	0.240681043098804
GO:0140674	ATP-dependent histone chaperone activity	17/1191	152/18639	0.111842105263158	1.75031486146096	0.0173171721235476	0.240681043098804
GO:0140597	protein carrier chaperone	20/1191	188/18639	0.106382978723404	1.66488021866124	0.0174011289551423	0.240681043098804
GO:0140713	histone chaperone activity	18/1191	164/18639	0.109756097560976	1.71766910364318	0.0174506825854625	0.240681043098804
GO:0051117	ATPase binding	11/1191	84/18639	0.130952380952381	2.04938826916157	0.0176945630730092	0.240681043098804
GO:0061775	cohesin loader activity	17/1191	153/18639	0.111111111111111	1.73887489504618	0.0183636753931864	0.240681043098804
GO:0004864	protein phosphatase inhibitor activity	8/1191	53/18639	0.150943396226415	2.36224514044009	0.0185139263922157	0.240681043098804
GO:0005246	calcium channel regulator activity	8/1191	53/18639	0.150943396226415	2.36224514044009	0.0185139263922157	0.240681043098804
GO:0140296	general transcription initiation factor binding	8/1191	53/18639	0.150943396226415	2.36224514044009	0.0185139263922157	0.240681043098804
GO:0019888	protein phosphatase regulator activity	13/1191	107/18639	0.121495327102804	1.9013865674804	0.0188223897670781	0.241878525972336
GO:0019902	phosphatase binding	20/1191	190/18639	0.105263157894737	1.64735516372796	0.0193053151578556	0.245265253937302
GO:0070402	NADPH binding	4/1191	17/18639	0.235294117647059	3.68232330715662	0.0202002072105011	0.25332854136789
GO:0140297	DNA-binding transcription factor binding	43/1191	488/18639	0.0881147540983607	1.37898480406326	0.0203931741709392	0.25332854136789
GO:0016209	antioxidant activity	11/1191	86/18639	0.127906976744186	2.00172807685549	0.0207802861252233	0.255300658109886
GO:0003924	GTPase activity	31/1191	331/18639	0.0936555891238671	1.46569817437427	0.0212517431799274	0.258254879077814
GO:0019903	protein phosphatase binding	16/1191	144/18639	0.111111111111111	1.73887489504618	0.0216943017714305	0.260798165381283
GO:0008140	cAMP response element binding protein binding	3/1191	10/18639	0.3	4.69496221662468	0.0222447856635004	0.261786003913615
GO:0098505	G-rich strand telomeric DNA binding	3/1191	10/18639	0.3	4.69496221662468	0.0222447856635004	0.261786003913615
GO:0050681	nuclear androgen receptor binding	5/1191	26/18639	0.192307692307692	3.009591164503	0.0225754550248681	0.262909986643777
GO:0003713	transcription coactivator activity	25/1191	256/18639	0.09765625	1.52830801322418	0.0229806804426948	0.264870110669411
GO:0008235	metalloexopeptidase activity	9/1191	66/18639	0.136363636363636	2.1340737348294	0.0239085462699753	0.272752599284004
GO:0140658	ATP-dependent chromatin remodeler activity	17/1191	158/18639	0.107594936708861	1.68384720849409	0.0243426559438287	0.274899892375763
GO:0098641	cadherin binding involved in cell-cell adhesion	4/1191	18/18639	0.222222222222222	3.47774979009236	0.0246886793555755	0.276019435195334
GO:0003712	transcription coregulator activity	43/1191	495/18639	0.0868686868686869	1.35948400885429	0.0251826617951397	0.27875461274224
GO:0004857	enzyme inhibitor activity	37/1191	416/18639	0.0889423076923077	1.39193591358264	0.0262783555090028	0.28803138685358
GO:0140223	general transcription initiation factor activity	9/1191	68/18639	0.132352941176471	2.0713068602756	0.0284491902479639	0.307960014466293
GO:0016922	nuclear receptor binding	15/1191	137/18639	0.109489051094891	1.713489860082	0.0288149345777134	0.307960014466293
GO:1990948	ubiquitin ligase inhibitor activity	3/1191	11/18639	0.272727272727273	4.2681474696588	0.0291591830522351	0.307960014466293
GO:0042277	peptide binding	24/1191	249/18639	0.0963855421686747	1.50842159570271	0.0291983555755162	0.307960014466293
GO:0046624	sphingolipid transporter activity	4/1191	19/18639	0.210526315789474	3.29471032745592	0.0297315034817057	0.310652531706047
GO:0015368	calcium:monoatomic cation antiporter activity	3/1191	12/18639	0.25	3.9124685138539	0.0370711554417974	0.38023442003605
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/1191	12/18639	0.25	3.9124685138539	0.0370711554417974	0.38023442003605
GO:0016853	isomerase activity	18/1191	180/18639	0.1	1.56498740554156	0.0395921924179058	0.399643725098609
GO:0051721	protein phosphatase 2A binding	5/1191	30/18639	0.166666666666667	2.60831234256927	0.0396784020446741	0.399643725098609
GO:0016887	ATP hydrolysis activity	36/1191	417/18639	0.0863309352517986	1.35106826377689	0.0409200609225214	0.408469893851597
GO:0019955	cytokine binding	15/1191	144/18639	0.104166666666667	1.63019521410579	0.0421185292064948	0.416712527901426
GO:0042169	SH2 domain binding	6/1191	41/18639	0.146341463414634	2.29022547152424	0.0444753920971872	0.435451401423743
GO:0031491	nucleosome binding	9/1191	74/18639	0.121621621621622	1.90336306079379	0.0456176088740586	0.435451401423743
GO:0008035	high-density lipoprotein particle binding	3/1191	13/18639	0.230769230769231	3.6115093974036	0.0459599869123449	0.435451401423743
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/1191	13/18639	0.230769230769231	3.6115093974036	0.0459599869123449	0.435451401423743
GO:0097157	pre-mRNA intronic binding	3/1191	13/18639	0.230769230769231	3.6115093974036	0.0459599869123449	0.435451401423743
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/1191	22/18639	0.181818181818182	2.8454316464392	0.0482590064401988	0.449613076667852
GO:0061133	endopeptidase activator activity	4/1191	22/18639	0.181818181818182	2.8454316464392	0.0482590064401988	0.449613076667852
GO:0031625	ubiquitin protein ligase binding	27/1191	302/18639	0.0894039735099338	1.39916092548418	0.04891699421722	0.450847409215258
GO:0048487	beta-tubulin binding	6/1191	42/18639	0.142857142857143	2.2356962936308	0.049198017821343	0.450847409215258
GO:0030515	snoRNA binding	5/1191	32/18639	0.15625	2.44529282115869	0.0505372194324691	0.452284801305084
GO:0016251	RNA polymerase II general transcription initiation factor activity	7/1191	53/18639	0.132075471698113	2.06696449788508	0.0505685153516418	0.452284801305084
GO:0016860	intramolecular oxidoreductase activity	7/1191	53/18639	0.132075471698113	2.06696449788508	0.0505685153516418	0.452284801305084
GO:0098631	cell adhesion mediator activity	9/1191	76/18639	0.118421052631579	1.85327455919395	0.0526057984617881	0.455319313813751
GO:0038024	cargo receptor activity	8/1191	65/18639	0.123076923076923	1.92613834528192	0.0542706865200052	0.455319313813751
GO:0050661	NADP binding	7/1191	54/18639	0.12962962962963	2.02868737755388	0.0550384752385202	0.455319313813751
GO:0051287	NAD binding	7/1191	54/18639	0.12962962962963	2.02868737755388	0.0550384752385202	0.455319313813751
GO:0017134	fibroblast growth factor binding	4/1191	23/18639	0.173913043478261	2.7217172270288	0.0555714860503664	0.455319313813751
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/1191	23/18639	0.173913043478261	2.7217172270288	0.0555714860503664	0.455319313813751
GO:0004065	arylsulfatase activity	3/1191	14/18639	0.214285714285714	3.3535444404462	0.0557949427481967	0.455319313813751
GO:0005161	platelet-derived growth factor receptor binding	3/1191	14/18639	0.214285714285714	3.3535444404462	0.0557949427481967	0.455319313813751
GO:0005545	1-phosphatidylinositol binding	3/1191	14/18639	0.214285714285714	3.3535444404462	0.0557949427481967	0.455319313813751
GO:0008494	translation activator activity	3/1191	14/18639	0.214285714285714	3.3535444404462	0.0557949427481967	0.455319313813751
GO:0008559	ABC-type xenobiotic transporter activity	3/1191	14/18639	0.214285714285714	3.3535444404462	0.0557949427481967	0.455319313813751
GO:0070742	C2H2 zinc finger domain binding	3/1191	14/18639	0.214285714285714	3.3535444404462	0.0557949427481967	0.455319313813751
GO:0003727	single-stranded RNA binding	10/1191	89/18639	0.112359550561798	1.75841281521524	0.0573035059315423	0.464241446604813
GO:0106310	protein serine kinase activity	31/1191	361/18639	0.0858725761772853	1.3438950019886	0.057738549655839	0.464400708742648
GO:0001223	transcription coactivator binding	6/1191	44/18639	0.136363636363636	2.1340737348294	0.0595349704060651	0.475429263671291
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/1191	24/18639	0.166666666666667	2.60831234256927	0.0634446375434075	0.476849781116489
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/1191	24/18639	0.166666666666667	2.60831234256927	0.0634446375434075	0.476849781116489
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/1191	24/18639	0.166666666666667	2.60831234256927	0.0634446375434075	0.476849781116489
GO:0004622	lysophospholipase activity	4/1191	24/18639	0.166666666666667	2.60831234256927	0.0634446375434075	0.476849781116489
GO:0070840	dynein complex binding	4/1191	24/18639	0.166666666666667	2.60831234256927	0.0634446375434075	0.476849781116489
GO:0016835	carbon-oxygen lyase activity	9/1191	79/18639	0.113924050632911	1.78289704428786	0.0643384247479583	0.476849781116489
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0005523	tropomyosin binding	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0030553	cGMP binding	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0031005	filamin binding	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0042809	nuclear vitamin D receptor binding	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0051371	muscle alpha-actinin binding	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0061578	K63-linked deubiquitinase activity	3/1191	15/18639	0.2	3.12997481108312	0.0665371787604403	0.476849781116489
GO:0000149	SNARE binding	11/1191	106/18639	0.10377358490566	1.62404353405256	0.07581622258976	0.529467272414653
GO:0008013	beta-catenin binding	11/1191	106/18639	0.10377358490566	1.62404353405256	0.07581622258976	0.529467272414653
GO:0097110	scaffold protein binding	8/1191	70/18639	0.114285714285714	1.78855703490464	0.0772055021205442	0.529467272414653
GO:0140359	ABC-type transporter activity	6/1191	47/18639	0.127659574468085	1.99785626239348	0.0772837316270805	0.529467272414653
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/1191	16/18639	0.1875	2.93435138539043	0.0781414131917869	0.529467272414653
GO:0008142	oxysterol binding	3/1191	16/18639	0.1875	2.93435138539043	0.0781414131917869	0.529467272414653
GO:0070411	I-SMAD binding	3/1191	16/18639	0.1875	2.93435138539043	0.0781414131917869	0.529467272414653
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	3/1191	16/18639	0.1875	2.93435138539043	0.0781414131917869	0.529467272414653
GO:0140328	floppase activity	3/1191	16/18639	0.1875	2.93435138539043	0.0781414131917869	0.529467272414653
GO:0008094	ATP-dependent activity, acting on DNA	19/1191	210/18639	0.0904761904761905	1.41594098596617	0.0796780564154274	0.529474321957704
GO:0008237	metallopeptidase activity	17/1191	184/18639	0.0923913043478261	1.44591227685905	0.0806511122238548	0.529474321957704
GO:0061135	endopeptidase regulator activity	17/1191	184/18639	0.0923913043478261	1.44591227685905	0.0806511122238548	0.529474321957704
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/1191	26/18639	0.153846153846154	2.4076729316024	0.0808311881293486	0.529474321957704
GO:0005160	transforming growth factor beta receptor binding	4/1191	26/18639	0.153846153846154	2.4076729316024	0.0808311881293486	0.529474321957704
GO:0036002	pre-mRNA binding	7/1191	59/18639	0.11864406779661	1.85676471843914	0.0809839973656237	0.529474321957704
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	6/1191	48/18639	0.125	1.95623425692695	0.0837953636147659	0.544669863495978
GO:0044389	ubiquitin-like protein ligase binding	27/1191	322/18639	0.0838509316770186	1.3122565201746	0.0902679476179058	0.553241297478175
GO:0005044	scavenger receptor activity	4/1191	27/18639	0.148148148148148	2.31849986006157	0.0903165118986512	0.553241297478175
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/1191	27/18639	0.148148148148148	2.31849986006157	0.0903165118986512	0.553241297478175
GO:0004550	nucleoside diphosphate kinase activity	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0005092	GDP-dissociation inhibitor activity	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0008484	sulfuric ester hydrolase activity	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0016018	cyclosporin A binding	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0019198	transmembrane receptor protein phosphatase activity	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0051787	misfolded protein binding	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0070492	oligosaccharide binding	3/1191	17/18639	0.176470588235294	2.76174248036746	0.0905573859020626	0.553241297478175
GO:0042162	telomeric DNA binding	5/1191	38/18639	0.131578947368421	2.05919395465995	0.0924970995198535	0.559254355245375
GO:0015026	coreceptor activity	7/1191	61/18639	0.114754098360656	1.79588718668704	0.0930423167045078	0.559254355245375
GO:0016836	hydro-lyase activity	7/1191	61/18639	0.114754098360656	1.79588718668704	0.0930423167045078	0.559254355245375
GO:0051019	mitogen-activated protein kinase binding	4/1191	28/18639	0.142857142857143	2.2356962936308	0.100306947505524	0.585714142536871
GO:0051393	alpha-actinin binding	4/1191	28/18639	0.142857142857143	2.2356962936308	0.100306947505524	0.585714142536871
GO:0097718	disordered domain specific binding	4/1191	28/18639	0.142857142857143	2.2356962936308	0.100306947505524	0.585714142536871
GO:0003714	transcription corepressor activity	18/1191	204/18639	0.0882352941176471	1.38087124018373	0.102991230915284	0.585714142536871
GO:0008081	phosphoric diester hydrolase activity	9/1191	87/18639	0.103448275862069	1.61895248849127	0.103156557388021	0.585714142536871
GO:0000900	mRNA regulatory element binding translation repressor activity	3/1191	18/18639	0.166666666666667	2.60831234256927	0.10373112721136	0.585714142536871
GO:0008525	phosphatidylcholine transporter activity	3/1191	18/18639	0.166666666666667	2.60831234256927	0.10373112721136	0.585714142536871
GO:0015373	monoatomic anion:sodium symporter activity	3/1191	18/18639	0.166666666666667	2.60831234256927	0.10373112721136	0.585714142536871
GO:0017075	syntaxin-1 binding	3/1191	18/18639	0.166666666666667	2.60831234256927	0.10373112721136	0.585714142536871
GO:0031690	adrenergic receptor binding	3/1191	18/18639	0.166666666666667	2.60831234256927	0.10373112721136	0.585714142536871
GO:0070064	proline-rich region binding	3/1191	18/18639	0.166666666666667	2.60831234256927	0.10373112721136	0.585714142536871
GO:1990381	ubiquitin-specific protease binding	3/1191	18/18639	0.166666666666667	2.60831234256927	0.10373112721136	0.585714142536871
GO:0003725	double-stranded RNA binding	8/1191	75/18639	0.106666666666667	1.66931989924433	0.105148461416138	0.590733567151969
GO:0140996	histone H3 kinase activity	29/1191	357/18639	0.0812324929971989	1.27127828461359	0.109451238289806	0.611832422040017
GO:0051536	iron-sulfur cluster binding	8/1191	76/18639	0.105263157894737	1.64735516372796	0.111329951175473	0.618622806860132
GO:0005080	protein kinase C binding	6/1191	52/18639	0.115384615384615	1.8057546987018	0.112740280330601	0.618622806860132
GO:0003779	actin binding	35/1191	443/18639	0.0790067720090293	1.23644603146625	0.113739705001914	0.618622806860132
GO:0008017	microtubule binding	23/1191	276/18639	0.0833333333333333	1.30415617128463	0.116266068274764	0.618622806860132
GO:0008238	exopeptidase activity	10/1191	102/18639	0.0980392156862745	1.53430137798192	0.116395363904066	0.618622806860132
GO:0003756	protein disulfide isomerase activity	3/1191	19/18639	0.157894736842105	2.47103274559194	0.11760605666067	0.618622806860132
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/1191	19/18639	0.157894736842105	2.47103274559194	0.11760605666067	0.618622806860132
GO:0043395	heparan sulfate proteoglycan binding	3/1191	19/18639	0.157894736842105	2.47103274559194	0.11760605666067	0.618622806860132
GO:0050145	nucleoside monophosphate kinase activity	3/1191	19/18639	0.157894736842105	2.47103274559194	0.11760605666067	0.618622806860132
GO:1990380	K48-linked deubiquitinase activity	3/1191	19/18639	0.157894736842105	2.47103274559194	0.11760605666067	0.618622806860132
GO:0003724	RNA helicase activity	8/1191	77/18639	0.103896103896104	1.6259609408224	0.117704644010223	0.618622806860132
GO:0051540	metal cluster binding	8/1191	77/18639	0.103896103896104	1.6259609408224	0.117704644010223	0.618622806860132
GO:0035173	histone kinase activity	29/1191	360/18639	0.0805555555555556	1.26068429890848	0.117859264634354	0.618622806860132
GO:0004386	helicase activity	14/1191	155/18639	0.0903225806451613	1.41353701145689	0.120446577847368	0.629248944081108
GO:0035925	mRNA 3'-UTR AU-rich region binding	4/1191	30/18639	0.133333333333333	2.08664987405542	0.121721693951511	0.632952808547856
GO:0004674	protein serine/threonine kinase activity	34/1191	433/18639	0.0785219399538106	1.22885847086404	0.124652349471574	0.639456942692438
GO:0031492	nucleosomal DNA binding	5/1191	42/18639	0.119047619047619	1.86308024469234	0.127901702306507	0.639456942692438
GO:0035198	miRNA binding	5/1191	42/18639	0.119047619047619	1.86308024469234	0.127901702306507	0.639456942692438
GO:0005522	profilin binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0005528	FK506 binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0030957	Tat protein binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0032356	oxidized DNA binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0043295	glutathione binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0047429	nucleoside triphosphate diphosphatase activity	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0051880	G-quadruplex DNA binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0070097	delta-catenin binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0070513	death domain binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0097177	mitochondrial ribosome binding	2/1191	10/18639	0.2	3.12997481108312	0.130578098493391	0.639456942692438
GO:0008186	ATP-dependent activity, acting on RNA	8/1191	79/18639	0.10126582278481	1.58479737270032	0.131022747303432	0.639456942692438
GO:0016004	phospholipase activator activity	3/1191	20/18639	0.15	2.34748110831234	0.132123930019636	0.639456942692438
GO:0042288	MHC class I protein binding	3/1191	20/18639	0.15	2.34748110831234	0.132123930019636	0.639456942692438
GO:0017147	Wnt-protein binding	4/1191	31/18639	0.129032258064516	2.01933858779556	0.133100960706951	0.641408939958496
GO:0140313	molecular sequestering activity	6/1191	55/18639	0.109090909090909	1.70725898786352	0.137347453911524	0.6507979376364
GO:0004712	protein serine/threonine/tyrosine kinase activity	5/1191	43/18639	0.116279069767442	1.81975279714135	0.137597025622458	0.6507979376364
GO:0005245	voltage-gated calcium channel activity	5/1191	43/18639	0.116279069767442	1.81975279714135	0.137597025622458	0.6507979376364
GO:0008200	ion channel inhibitor activity	5/1191	43/18639	0.116279069767442	1.81975279714135	0.137597025622458	0.6507979376364
GO:0048306	calcium-dependent protein binding	8/1191	80/18639	0.1	1.56498740554156	0.137959849033834	0.6507979376364
GO:0031267	small GTPase binding	23/1191	283/18639	0.0812720848056537	1.27189789142954	0.140458127654974	0.653371298544075
GO:0032934	sterol binding	7/1191	68/18639	0.102941176470588	1.61101644688102	0.142510338333609	0.653371298544075
GO:0141003	histone H2AX kinase activity	28/1191	354/18639	0.0790960451977401	1.23784314562609	0.142748432111251	0.653371298544075
GO:0031369	translation initiation factor binding	4/1191	32/18639	0.125	1.95623425692695	0.14489578088902	0.653371298544075
GO:0042910	xenobiotic transmembrane transporter activity	4/1191	32/18639	0.125	1.95623425692695	0.14489578088902	0.653371298544075
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/1191	21/18639	0.142857142857143	2.2356962936308	0.147225651112196	0.653371298544075
GO:0010314	phosphatidylinositol-5-phosphate binding	3/1191	21/18639	0.142857142857143	2.2356962936308	0.147225651112196	0.653371298544075
GO:0036122	BMP binding	3/1191	21/18639	0.142857142857143	2.2356962936308	0.147225651112196	0.653371298544075
GO:0051010	microtubule plus-end binding	3/1191	21/18639	0.142857142857143	2.2356962936308	0.147225651112196	0.653371298544075
GO:0001046	core promoter sequence-specific DNA binding	5/1191	44/18639	0.113636363636364	1.7783947790245	0.147604981419432	0.653371298544075
GO:0016248	channel inhibitor activity	5/1191	44/18639	0.113636363636364	1.7783947790245	0.147604981419432	0.653371298544075
GO:0000287	magnesium ion binding	19/1191	230/18639	0.0826086956521739	1.29281568283868	0.151093527610318	0.653371298544075
GO:0015631	tubulin binding	30/1191	385/18639	0.0779220779220779	1.2194707056168	0.151230714748931	0.653371298544075
GO:0005114	type II transforming growth factor beta receptor binding	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0008172	S-methyltransferase activity	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0019206	nucleoside kinase activity	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0034713	type I transforming growth factor beta receptor binding	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0050786	RAGE receptor binding	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0050998	nitric-oxide synthase binding	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0070697	activin receptor binding	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0097493	structural molecule activity conferring elasticity	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:1900750	oligopeptide binding	2/1191	11/18639	0.181818181818182	2.8454316464392	0.153115635258093	0.653371298544075
GO:0051020	GTPase binding	25/1191	315/18639	0.0793650793650794	1.24205349646156	0.154706031104487	0.657647691159
GO:0019956	chemokine binding	4/1191	33/18639	0.121212121212121	1.89695443095947	0.157080488094674	0.661217811181506
GO:0140311	protein sequestering activity	4/1191	33/18639	0.121212121212121	1.89695443095947	0.157080488094674	0.661217811181506
GO:0051539	4 iron, 4 sulfur cluster binding	5/1191	45/18639	0.111111111111111	1.73887489504618	0.157911588180199	0.661217811181506
GO:0141110	transporter inhibitor activity	5/1191	45/18639	0.111111111111111	1.73887489504618	0.157911588180199	0.661217811181506
GO:0030165	PDZ domain binding	8/1191	83/18639	0.0963855421686747	1.50842159570271	0.159838681030153	0.666789721610861
GO:0016881	acid-amino acid ligase activity	3/1191	22/18639	0.136363636363636	2.1340737348294	0.162851963428827	0.669369467328783
GO:0034062	5'-3' RNA polymerase activity	3/1191	22/18639	0.136363636363636	2.1340737348294	0.162851963428827	0.669369467328783
GO:0097747	RNA polymerase activity	3/1191	22/18639	0.136363636363636	2.1340737348294	0.162851963428827	0.669369467328783
GO:0140517	protein-RNA adaptor activity	3/1191	22/18639	0.136363636363636	2.1340737348294	0.162851963428827	0.669369467328783
GO:0035403	histone H3T6 kinase activity	20/1191	247/18639	0.0809716599190283	1.26719627979074	0.164222514009999	0.670090767354311
GO:0061980	regulatory RNA binding	6/1191	58/18639	0.103448275862069	1.61895248849127	0.164226180907944	0.670090767354311
GO:0004222	metalloendopeptidase activity	10/1191	110/18639	0.0909090909090909	1.4227158232196	0.165059196590547	0.671040661048116
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	5/1191	46/18639	0.108695652173913	1.701073266893	0.16850218450699	0.68255595028556
GO:0004859	phospholipase inhibitor activity	2/1191	12/18639	0.166666666666667	2.60831234256927	0.176324531221352	0.696575356556435
GO:0005527	macrolide binding	2/1191	12/18639	0.166666666666667	2.60831234256927	0.176324531221352	0.696575356556435
GO:0008504	monoamine transmembrane transporter activity	2/1191	12/18639	0.166666666666667	2.60831234256927	0.176324531221352	0.696575356556435
GO:0035197	siRNA binding	2/1191	12/18639	0.166666666666667	2.60831234256927	0.176324531221352	0.696575356556435
GO:0035497	cAMP response element binding	2/1191	12/18639	0.166666666666667	2.60831234256927	0.176324531221352	0.696575356556435
GO:0045295	gamma-catenin binding	2/1191	12/18639	0.166666666666667	2.60831234256927	0.176324531221352	0.696575356556435
GO:0070679	inositol 1,4,5 trisphosphate binding	2/1191	12/18639	0.166666666666667	2.60831234256927	0.176324531221352	0.696575356556435
GO:0003774	cytoskeletal motor activity	13/1191	153/18639	0.0849673202614379	1.32972786091767	0.180146338500659	0.709167628323018
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	8/1191	86/18639	0.0930232558139535	1.45580223771308	0.183226610165046	0.718762632156216
GO:0016247	channel regulator activity	14/1191	168/18639	0.0833333333333333	1.30415617128463	0.187162578335374	0.731635533492826
GO:0140693	molecular condensate scaffold activity	5/1191	48/18639	0.104166666666667	1.63019521410579	0.190473868382153	0.733214368415834
GO:0030414	peptidase inhibitor activity	14/1191	169/18639	0.0828402366863905	1.29643927086283	0.19292147736129	0.733214368415834
GO:0031490	chromatin DNA binding	11/1191	128/18639	0.0859375	1.34491105163728	0.195247180333801	0.733214368415834
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	11/1191	128/18639	0.0859375	1.34491105163728	0.195247180333801	0.733214368415834
GO:0005540	hyaluronic acid binding	3/1191	24/18639	0.125	1.95623425692695	0.195443948963052	0.733214368415834
GO:0050699	WW domain binding	3/1191	24/18639	0.125	1.95623425692695	0.195443948963052	0.733214368415834
GO:0060229	lipase activator activity	3/1191	24/18639	0.125	1.95623425692695	0.195443948963052	0.733214368415834
GO:0000993	RNA polymerase II complex binding	4/1191	36/18639	0.111111111111111	1.73887489504618	0.195706139646446	0.733214368415834
GO:0005484	SNAP receptor activity	4/1191	36/18639	0.111111111111111	1.73887489504618	0.195706139646446	0.733214368415834
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/1191	36/18639	0.111111111111111	1.73887489504618	0.195706139646446	0.733214368415834
GO:0141108	transporter regulator activity	14/1191	170/18639	0.0823529411764706	1.28881315750482	0.198762716898906	0.733214368415834
GO:0035401	histone H3Y41 kinase activity	10/1191	115/18639	0.0869565217391304	1.3608586135144	0.199744473138197	0.733214368415834
GO:0140801	histone H2AXY142 kinase activity	10/1191	115/18639	0.0869565217391304	1.3608586135144	0.199744473138197	0.733214368415834
GO:0019855	calcium channel inhibitor activity	2/1191	13/18639	0.153846153846154	2.4076729316024	0.200027175641171	0.733214368415834
GO:0035325	Toll-like receptor binding	2/1191	13/18639	0.153846153846154	2.4076729316024	0.200027175641171	0.733214368415834
GO:0035673	oligopeptide transmembrane transporter activity	2/1191	13/18639	0.153846153846154	2.4076729316024	0.200027175641171	0.733214368415834
GO:0046974	histone H3K9 methyltransferase activity	2/1191	13/18639	0.153846153846154	2.4076729316024	0.200027175641171	0.733214368415834
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/1191	13/18639	0.153846153846154	2.4076729316024	0.200027175641171	0.733214368415834
GO:1901338	catecholamine binding	2/1191	13/18639	0.153846153846154	2.4076729316024	0.200027175641171	0.733214368415834
GO:0044183	protein folding chaperone	7/1191	75/18639	0.0933333333333333	1.46065491183879	0.202068373487336	0.734620689430754
GO:0030551	cyclic nucleotide binding	4/1191	37/18639	0.108108108108108	1.69187827626115	0.209180336822218	0.734620689430754
GO:0042805	actinin binding	4/1191	37/18639	0.108108108108108	1.69187827626115	0.209180336822218	0.734620689430754
GO:0017022	myosin binding	7/1191	76/18639	0.0921052631578947	1.44143576826196	0.211273720678395	0.734620689430754
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	19/1191	243/18639	0.0781893004115226	1.22365270392139	0.21189733222805	0.734620689430754
GO:0004709	MAP kinase kinase kinase activity	3/1191	25/18639	0.12	1.87798488664987	0.212295110050959	0.734620689430754
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/1191	25/18639	0.12	1.87798488664987	0.212295110050959	0.734620689430754
GO:0017056	structural constituent of nuclear pore	3/1191	25/18639	0.12	1.87798488664987	0.212295110050959	0.734620689430754
GO:0004676	3-phosphoinositide-dependent protein kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0004711	ribosomal protein S6 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0035175	histone H3S10 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0035979	histone H2AXS139 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0044022	histone H3S28 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0044023	histone H4S1 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0044024	histone H2AS1 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0044025	histone H2BS14 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0072354	histone H3T3 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0072371	histone H2AS121 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0072518	Rho-dependent protein serine/threonine kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0140823	histone H2BS36 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0140855	histone H3S57 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0140995	histone H2A kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0140997	histone H4 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0140998	histone H2B kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:1990244	histone H2AT120 kinase activity	19/1191	245/18639	0.0775510204081633	1.21366370225672	0.222149833965665	0.734620689430754
GO:0000146	microfilament motor activity	4/1191	38/18639	0.105263157894737	1.64735516372796	0.222907776504849	0.734620689430754
GO:0005109	frizzled binding	4/1191	38/18639	0.105263157894737	1.64735516372796	0.222907776504849	0.734620689430754
GO:0043531	ADP binding	4/1191	38/18639	0.105263157894737	1.64735516372796	0.222907776504849	0.734620689430754
GO:0099106	ion channel regulator activity	13/1191	160/18639	0.08125	1.27155226700252	0.223400034303369	0.734620689430754
GO:0004705	JUN kinase activity	2/1191	14/18639	0.142857142857143	2.2356962936308	0.224065881123334	0.734620689430754
GO:0008331	high voltage-gated calcium channel activity	2/1191	14/18639	0.142857142857143	2.2356962936308	0.224065881123334	0.734620689430754
GO:0016530	metallochaperone activity	2/1191	14/18639	0.142857142857143	2.2356962936308	0.224065881123334	0.734620689430754
GO:0031404	chloride ion binding	2/1191	14/18639	0.142857142857143	2.2356962936308	0.224065881123334	0.734620689430754
GO:0044548	S100 protein binding	2/1191	14/18639	0.142857142857143	2.2356962936308	0.224065881123334	0.734620689430754
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/1191	14/18639	0.142857142857143	2.2356962936308	0.224065881123334	0.734620689430754
GO:0071933	Arp2/3 complex binding	2/1191	14/18639	0.142857142857143	2.2356962936308	0.224065881123334	0.734620689430754
GO:0072341	modified amino acid binding	8/1191	91/18639	0.0879120879120879	1.3758131037728	0.225182394939841	0.735698960261999
GO:0004677	DNA-dependent protein kinase activity	19/1191	246/18639	0.0772357723577236	1.20873010997112	0.227358018362262	0.735698960261999
GO:0140857	histone H3T45 kinase activity	19/1191	246/18639	0.0772357723577236	1.20873010997112	0.227358018362262	0.735698960261999
GO:0005112	Notch binding	3/1191	26/18639	0.115384615384615	1.8057546987018	0.229442578127691	0.735698960261999
GO:0019865	immunoglobulin binding	3/1191	26/18639	0.115384615384615	1.8057546987018	0.229442578127691	0.735698960261999
GO:0050750	low-density lipoprotein particle receptor binding	3/1191	26/18639	0.115384615384615	1.8057546987018	0.229442578127691	0.735698960261999
GO:0070412	R-SMAD binding	3/1191	26/18639	0.115384615384615	1.8057546987018	0.229442578127691	0.735698960261999
GO:0004866	endopeptidase inhibitor activity	13/1191	161/18639	0.0807453416149068	1.2636544268348	0.229909949819745	0.735698960261999
GO:0015085	calcium ion transmembrane transporter activity	12/1191	147/18639	0.0816326530612245	1.2775407392176	0.230317205806529	0.735698960261999
GO:0042578	phosphoric ester hydrolase activity	27/1191	363/18639	0.0743801652892562	1.16404021899786	0.232324173032141	0.73883065061883
GO:0035402	histone H3T11 kinase activity	19/1191	247/18639	0.0769230769230769	1.2038364658012	0.232619310391617	0.73883065061883
GO:0004679	AMP-activated protein kinase activity	19/1191	248/18639	0.0766129032258065	1.19898228650362	0.237932533684101	0.753565361639731
GO:0140097	catalytic activity, acting on DNA	25/1191	336/18639	0.0744047619047619	1.16442515293271	0.242244043090231	0.764662848791813
GO:0001671	ATPase activator activity	3/1191	27/18639	0.111111111111111	1.73887489504618	0.246833336406321	0.764662848791813
GO:0005104	fibroblast growth factor receptor binding	3/1191	27/18639	0.111111111111111	1.73887489504618	0.246833336406321	0.764662848791813
GO:0008320	protein transmembrane transporter activity	3/1191	27/18639	0.111111111111111	1.73887489504618	0.246833336406321	0.764662848791813
GO:0004089	carbonate dehydratase activity	2/1191	15/18639	0.133333333333333	2.08664987405542	0.24830106610224	0.764662848791813
GO:0004129	cytochrome-c oxidase activity	2/1191	15/18639	0.133333333333333	2.08664987405542	0.24830106610224	0.764662848791813
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/1191	15/18639	0.133333333333333	2.08664987405542	0.24830106610224	0.764662848791813
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/1191	15/18639	0.133333333333333	2.08664987405542	0.24830106610224	0.764662848791813
GO:0140776	protein-containing complex destabilizing activity	2/1191	15/18639	0.133333333333333	2.08664987405542	0.24830106610224	0.764662848791813
GO:0005516	calmodulin binding	16/1191	207/18639	0.0772946859903382	1.20965210090169	0.250390985015855	0.764662848791813
GO:0015144	carbohydrate transmembrane transporter activity	4/1191	40/18639	0.1	1.56498740554156	0.251011865390515	0.764662848791813
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4/1191	40/18639	0.1	1.56498740554156	0.251011865390515	0.764662848791813
GO:0061791	GTPase motor activity	4/1191	40/18639	0.1	1.56498740554156	0.251011865390515	0.764662848791813
GO:1990606	membrane scission GTPase motor activity	4/1191	40/18639	0.1	1.56498740554156	0.251011865390515	0.764662848791813
GO:0016410	N-acyltransferase activity	8/1191	94/18639	0.0851063829787234	1.33190417492899	0.251883443543402	0.765232852938923
GO:0005496	steroid binding	9/1191	108/18639	0.0833333333333333	1.30415617128463	0.252870582590199	0.766149895219086
GO:0042054	histone methyltransferase activity	6/1191	67/18639	0.0895522388059701	1.40148125869394	0.255911040939463	0.773266334514377
GO:0001618	virus receptor activity	7/1191	81/18639	0.0864197530864197	1.35245825170258	0.25940930742887	0.775515316346789
GO:0004867	serine-type endopeptidase inhibitor activity	8/1191	95/18639	0.0842105263157895	1.31788413098237	0.261000456812465	0.775515316346789
GO:0015485	cholesterol binding	5/1191	54/18639	0.0925925925925926	1.44906241253848	0.261539407062148	0.775515316346789
GO:0140463	chromatin-protein adaptor activity	5/1191	54/18639	0.0925925925925926	1.44906241253848	0.261539407062148	0.775515316346789
GO:0050698	proteoglycan sulfotransferase activity	3/1191	28/18639	0.107142857142857	1.6767722202231	0.264416503074416	0.775515316346789
GO:0051537	2 iron, 2 sulfur cluster binding	3/1191	28/18639	0.107142857142857	1.6767722202231	0.264416503074416	0.775515316346789
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4/1191	41/18639	0.0975609756097561	1.52681698101616	0.265333989642649	0.775515316346789
GO:0140318	protein transporter activity	4/1191	41/18639	0.0975609756097561	1.52681698101616	0.265333989642649	0.775515316346789
GO:0140828	metal cation:monoatomic cation antiporter activity	4/1191	41/18639	0.0975609756097561	1.52681698101616	0.265333989642649	0.775515316346789
GO:0140272	exogenous protein binding	7/1191	82/18639	0.0853658536585366	1.33596485838914	0.269399463195142	0.775515316346789
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0004707	MAP kinase activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0004708	MAP kinase kinase activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0005024	transforming growth factor beta receptor activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0015378	sodium:chloride symporter activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0016722	oxidoreductase activity, acting on metal ions	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0022841	potassium ion leak channel activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0030275	LRR domain binding	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0055102	lipase inhibitor activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0140327	flippase activity	2/1191	16/18639	0.125	1.95623425692695	0.272609587946591	0.775515316346789
GO:0098632	cell-cell adhesion mediator activity	5/1191	55/18639	0.0909090909090909	1.4227158232196	0.27395860237721	0.777374917405383
GO:0008080	N-acetyltransferase activity	6/1191	69/18639	0.0869565217391304	1.3608586135144	0.277974702630601	0.784002532973587
GO:1902936	phosphatidylinositol bisphosphate binding	9/1191	111/18639	0.0810810810810811	1.26890870719586	0.278610116029548	0.784002532973587
GO:0019894	kinesin binding	4/1191	42/18639	0.0952380952380952	1.49046419575387	0.279800546204348	0.784002532973587
GO:0043175	RNA polymerase core enzyme binding	4/1191	42/18639	0.0952380952380952	1.49046419575387	0.279800546204348	0.784002532973587
GO:0051879	Hsp90 protein binding	4/1191	42/18639	0.0952380952380952	1.49046419575387	0.279800546204348	0.784002532973587
GO:0003785	actin monomer binding	3/1191	29/18639	0.103448275862069	1.61895248849127	0.282143493233318	0.784667724962313
GO:0004629	phospholipase C activity	3/1191	29/18639	0.103448275862069	1.61895248849127	0.282143493233318	0.784667724962313
GO:0099604	ligand-gated calcium channel activity	3/1191	29/18639	0.103448275862069	1.61895248849127	0.282143493233318	0.784667724962313
GO:0004713	protein tyrosine kinase activity	11/1191	140/18639	0.0785714285714286	1.22963296149694	0.282876788948461	0.784754962889279
GO:0042626	ATPase-coupled transmembrane transporter activity	8/1191	98/18639	0.0816326530612245	1.2775407392176	0.288908662965707	0.790274843434268
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0004659	prenyltransferase activity	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0008429	phosphatidylethanolamine binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0008569	minus-end-directed microtubule motor activity	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0015278	intracellularly gated calcium channel activity	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0016805	dipeptidase activity	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0030169	low-density lipoprotein particle binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0031489	myosin V binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0032183	SUMO binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0032977	membrane insertase activity	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0038191	neuropilin binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0045125	bioactive lipid receptor activity	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0045236	CXCR chemokine receptor binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0048038	quinone binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:1990226	histone methyltransferase binding	2/1191	17/18639	0.117647058823529	1.84116165357831	0.296883214885861	0.790274843434268
GO:0004601	peroxidase activity	5/1191	57/18639	0.087719298245614	1.3727959697733	0.299138346902	0.794386393910775
GO:0031210	phosphatidylcholine binding	3/1191	30/18639	0.1	1.56498740554156	0.299968137597964	0.79470231714342
GO:0043014	alpha-tubulin binding	4/1191	44/18639	0.0909090909090909	1.4227158232196	0.309063576799771	0.816863070596085
GO:0008408	3'-5' exonuclease activity	5/1191	58/18639	0.0862068965517241	1.34912707374273	0.311865909731628	0.819354427711943
GO:0008327	methyl-CpG binding	3/1191	31/18639	0.0967741935483871	1.51450394084667	0.317846763693429	0.819354427711943
GO:0047499	calcium-independent phospholipase A2 activity	3/1191	31/18639	0.0967741935483871	1.51450394084667	0.317846763693429	0.819354427711943
GO:0070273	phosphatidylinositol-4-phosphate binding	3/1191	31/18639	0.0967741935483871	1.51450394084667	0.317846763693429	0.819354427711943
GO:0070325	lipoprotein particle receptor binding	3/1191	31/18639	0.0967741935483871	1.51450394084667	0.317846763693429	0.819354427711943
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0004970	glutamate-gated receptor activity	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0008308	voltage-gated monoatomic anion channel activity	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0030228	lipoprotein particle receptor activity	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0034185	apolipoprotein binding	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0050811	GABA receptor binding	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0070628	proteasome binding	2/1191	18/18639	0.111111111111111	1.73887489504618	0.321027225845174	0.819354427711943
GO:0009055	electron transfer activity	9/1191	116/18639	0.0775862068965517	1.21421436636845	0.322981451587129	0.819354427711943
GO:0001217	DNA-binding transcription repressor activity	20/1191	278/18639	0.0719424460431655	1.12589021981407	0.323743210726397	0.819354427711943
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/1191	45/18639	0.0888888888888889	1.39109991603694	0.323810112274851	0.819354427711943
GO:0140303	intramembrane lipid transporter activity	4/1191	45/18639	0.0888888888888889	1.39109991603694	0.323810112274851	0.819354427711943
GO:0001786	phosphatidylserine binding	5/1191	59/18639	0.0847457627118644	1.32626051317081	0.324663695417165	0.819354427711943
GO:0004879	nuclear receptor activity	5/1191	59/18639	0.0847457627118644	1.32626051317081	0.324663695417165	0.819354427711943
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	5/1191	59/18639	0.0847457627118644	1.32626051317081	0.324663695417165	0.819354427711943
GO:0031072	heat shock protein binding	10/1191	131/18639	0.0763358778625954	1.19464687445921	0.327206487977755	0.823623331363723
GO:0004721	phosphoprotein phosphatase activity	13/1191	175/18639	0.0742857142857143	1.16256207268802	0.327828606848709	0.823623331363723
GO:1990782	protein tyrosine kinase binding	9/1191	117/18639	0.0769230769230769	1.2038364658012	0.332027156604879	0.828611487110395
GO:0003684	damaged DNA binding	6/1191	74/18639	0.0810810810810811	1.26890870719586	0.334740964233688	0.828611487110395
GO:0022884	macromolecule transmembrane transporter activity	3/1191	32/18639	0.09375	1.46717569269521	0.335738244673196	0.828611487110395
GO:0047498	calcium-dependent phospholipase A2 activity	3/1191	32/18639	0.09375	1.46717569269521	0.335738244673196	0.828611487110395
GO:0051059	NF-kappaB binding	3/1191	32/18639	0.09375	1.46717569269521	0.335738244673196	0.828611487110395
GO:0071813	lipoprotein particle binding	3/1191	32/18639	0.09375	1.46717569269521	0.335738244673196	0.828611487110395
GO:0071814	protein-lipid complex binding	3/1191	32/18639	0.09375	1.46717569269521	0.335738244673196	0.828611487110395
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	10/1191	132/18639	0.0757575757575758	1.18559651934967	0.335743294866734	0.828611487110395
GO:0098531	ligand-modulated transcription factor activity	5/1191	60/18639	0.0833333333333333	1.30415617128463	0.337515908323163	0.83115150992356
GO:0008083	growth factor activity	12/1191	162/18639	0.0740740740740741	1.15924993003079	0.340856428728988	0.837532939162656
GO:0008381	mechanosensitive monoatomic ion channel activity	2/1191	19/18639	0.105263157894737	1.64735516372796	0.344959128102174	0.840227244484162
GO:0022840	leak channel activity	2/1191	19/18639	0.105263157894737	1.64735516372796	0.344959128102174	0.840227244484162
GO:0022842	narrow pore channel activity	2/1191	19/18639	0.105263157894737	1.64735516372796	0.344959128102174	0.840227244484162
GO:0140036	ubiquitin-modified protein reader activity	2/1191	19/18639	0.105263157894737	1.64735516372796	0.344959128102174	0.840227244484162
GO:0019003	GDP binding	6/1191	75/18639	0.08	1.25198992443325	0.34627771125511	0.84160539387655
GO:0001784	phosphotyrosine residue binding	4/1191	47/18639	0.0851063829787234	1.33190417492899	0.353414349942493	0.853842969179507
GO:0140938	histone H3 methyltransferase activity	4/1191	47/18639	0.0851063829787234	1.33190417492899	0.353414349942493	0.853842969179507
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/1191	33/18639	0.0909090909090909	1.4227158232196	0.353604020331048	0.853842969179507
GO:0051015	actin filament binding	15/1191	209/18639	0.0717703349282297	1.12319670254179	0.358785892483942	0.862000915523859
GO:0035091	phosphatidylinositol binding	20/1191	284/18639	0.0704225352112676	1.10210380671941	0.358936325519086	0.862000915523859
GO:0032182	ubiquitin-like protein binding	9/1191	120/18639	0.075	1.17374055415617	0.359407978082669	0.862000915523859
GO:0004175	endopeptidase activity	28/1191	405/18639	0.0691358024691358	1.08196660136207	0.360066572047981	0.862000915523859
GO:0005543	phospholipid binding	34/1191	497/18639	0.06841046277666	1.07061512652743	0.364399304671953	0.86758561366558
GO:0016879	ligase activity, forming carbon-nitrogen bonds	4/1191	48/18639	0.0833333333333333	1.30415617128463	0.368227120993433	0.86758561366558
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/1191	20/18639	0.1	1.56498740554156	0.368607483444678	0.86758561366558
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/1191	20/18639	0.1	1.56498740554156	0.368607483444678	0.86758561366558
GO:0005326	neurotransmitter transmembrane transporter activity	2/1191	20/18639	0.1	1.56498740554156	0.368607483444678	0.86758561366558
GO:0015095	magnesium ion transmembrane transporter activity	2/1191	20/18639	0.1	1.56498740554156	0.368607483444678	0.86758561366558
GO:0016505	peptidase activator activity involved in apoptotic process	2/1191	20/18639	0.1	1.56498740554156	0.368607483444678	0.86758561366558
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/1191	20/18639	0.1	1.56498740554156	0.368607483444678	0.86758561366558
GO:0015399	primary active transmembrane transporter activity	12/1191	166/18639	0.072289156626506	1.13131619677703	0.372083895589129	0.873928141320685
GO:0043178	alcohol binding	7/1191	92/18639	0.0760869565217391	1.1907512868251	0.373422888625767	0.875234359504417
GO:0019207	kinase regulator activity	20/1191	287/18639	0.0696864111498258	1.09058355786868	0.376818377674659	0.881345075816461
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	9/1191	122/18639	0.0737704918032787	1.15449890572738	0.377810390856038	0.881820494732882
GO:0051219	phosphoprotein binding	7/1191	93/18639	0.0752688172043011	1.17794750954741	0.384049253307499	0.89451471916205
GO:0004623	phospholipase A2 activity	3/1191	35/18639	0.0857142857142857	1.34141777617848	0.389117011607001	0.904434135086543
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/1191	21/18639	0.0952380952380952	1.49046419575387	0.391910834216519	0.907155926820016
GO:0001846	opsonin binding	2/1191	21/18639	0.0952380952380952	1.49046419575387	0.391910834216519	0.907155926820016
GO:0042562	hormone binding	7/1191	94/18639	0.074468085106383	1.16541615306287	0.394683283978173	0.911685767536359
GO:0004620	phospholipase activity	8/1191	109/18639	0.073394495412844	1.14861460957179	0.395783106503386	0.911805578860454
GO:0070851	growth factor receptor binding	10/1191	139/18639	0.0719424460431655	1.12589021981407	0.39636628920052	0.911805578860454
GO:0016829	lyase activity	14/1191	200/18639	0.07	1.09549118387909	0.401718594557071	0.914688825706534
GO:0008276	protein methyltransferase activity	7/1191	95/18639	0.0736842105263158	1.15314861460957	0.405317145229991	0.914688825706534
GO:0045505	dynein intermediate chain binding	3/1191	36/18639	0.0833333333333333	1.30415617128463	0.40669981814887	0.914688825706534
GO:0055106	ubiquitin-protein transferase regulator activity	3/1191	36/18639	0.0833333333333333	1.30415617128463	0.40669981814887	0.914688825706534
GO:0030544	Hsp70 protein binding	4/1191	51/18639	0.0784313725490196	1.22744110238554	0.412458258513496	0.914688825706534
GO:0015377	chloride:monoatomic cation symporter activity	2/1191	22/18639	0.0909090909090909	1.4227158232196	0.414816721295288	0.914688825706534
GO:0050321	tau-protein kinase activity	2/1191	22/18639	0.0909090909090909	1.4227158232196	0.414816721295288	0.914688825706534
GO:0070034	telomerase RNA binding	2/1191	22/18639	0.0909090909090909	1.4227158232196	0.414816721295288	0.914688825706534
GO:0140035	ubiquitin-like protein reader activity	2/1191	22/18639	0.0909090909090909	1.4227158232196	0.414816721295288	0.914688825706534
GO:0030971	receptor tyrosine kinase binding	6/1191	81/18639	0.0740740740740741	1.15924993003079	0.415862734188761	0.914688825706534
GO:0004725	protein tyrosine phosphatase activity	7/1191	98/18639	0.0714285714285714	1.1178481468154	0.437141972043492	0.914688825706534
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/1191	23/18639	0.0869565217391304	1.3608586135144	0.437280786653353	0.914688825706534
GO:0016493	C-C chemokine receptor activity	2/1191	23/18639	0.0869565217391304	1.3608586135144	0.437280786653353	0.914688825706534
GO:0031681	G-protein beta-subunit binding	2/1191	23/18639	0.0869565217391304	1.3608586135144	0.437280786653353	0.914688825706534
GO:0140103	catalytic activity, acting on a glycoprotein	2/1191	23/18639	0.0869565217391304	1.3608586135144	0.437280786653353	0.914688825706534
GO:0003777	microtubule motor activity	5/1191	68/18639	0.0735294117647059	1.15072603348644	0.440528852364189	0.914688825706534
GO:0005548	phospholipid transporter activity	5/1191	68/18639	0.0735294117647059	1.15072603348644	0.440528852364189	0.914688825706534
GO:0005501	retinoid binding	3/1191	38/18639	0.0789473684210526	1.23551637279597	0.441375456063936	0.914688825706534
GO:0019840	isoprenoid binding	3/1191	38/18639	0.0789473684210526	1.23551637279597	0.441375456063936	0.914688825706534
GO:0042887	amide transmembrane transporter activity	3/1191	38/18639	0.0789473684210526	1.23551637279597	0.441375456063936	0.914688825706534
GO:0005544	calcium-dependent phospholipid binding	4/1191	53/18639	0.0754716981132075	1.18112257022005	0.441584607326146	0.914688825706534
GO:0008146	sulfotransferase activity	4/1191	53/18639	0.0754716981132075	1.18112257022005	0.441584607326146	0.914688825706534
GO:0051018	protein kinase A binding	4/1191	53/18639	0.0754716981132075	1.18112257022005	0.441584607326146	0.914688825706534
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	18/1191	268/18639	0.0671641791044776	1.05111094402045	0.448396377879986	0.914688825706534
GO:0004527	exonuclease activity	6/1191	84/18639	0.0714285714285714	1.1178481468154	0.45043603334773	0.914688825706534
GO:0004860	protein kinase inhibitor activity	6/1191	84/18639	0.0714285714285714	1.1178481468154	0.45043603334773	0.914688825706534
GO:0016298	lipase activity	9/1191	130/18639	0.0692307692307692	1.08345281922108	0.45169406287313	0.914688825706534
GO:0016279	protein-lysine N-methyltransferase activity	5/1191	69/18639	0.072463768115942	1.13404884459533	0.453228395312125	0.914688825706534
GO:0003925	G protein activity	4/1191	54/18639	0.0740740740740741	1.15924993003079	0.455988223347266	0.914688825706534
GO:0017069	snRNA binding	4/1191	54/18639	0.0740740740740741	1.15924993003079	0.455988223347266	0.914688825706534
GO:0043130	ubiquitin binding	7/1191	100/18639	0.07	1.09549118387909	0.458222149124976	0.914688825706534
GO:0015295	solute:proton symporter activity	2/1191	24/18639	0.0833333333333333	1.30415617128463	0.459265953716108	0.914688825706534
GO:0019957	C-C chemokine binding	2/1191	24/18639	0.0833333333333333	1.30415617128463	0.459265953716108	0.914688825706534
GO:0030215	semaphorin receptor binding	2/1191	24/18639	0.0833333333333333	1.30415617128463	0.459265953716108	0.914688825706534
GO:0030552	cAMP binding	2/1191	24/18639	0.0833333333333333	1.30415617128463	0.459265953716108	0.914688825706534
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1191	24/18639	0.0833333333333333	1.30415617128463	0.459265953716108	0.914688825706534
GO:0140033	acetylation-dependent protein binding	2/1191	24/18639	0.0833333333333333	1.30415617128463	0.459265953716108	0.914688825706534
GO:0005262	calcium channel activity	9/1191	131/18639	0.0687022900763359	1.07518218701329	0.46087757249656	0.914688825706534
GO:0019887	protein kinase regulator activity	17/1191	255/18639	0.0666666666666667	1.04332493702771	0.464290174439949	0.914688825706534
GO:0016278	lysine N-methyltransferase activity	5/1191	70/18639	0.0714285714285714	1.1178481468154	0.465848461562801	0.914688825706534
GO:0016782	transferase activity, transferring sulphur-containing groups	5/1191	70/18639	0.0714285714285714	1.1178481468154	0.465848461562801	0.914688825706534
GO:0030331	nuclear estrogen receptor binding	3/1191	40/18639	0.075	1.17374055415617	0.4752350884254	0.914688825706534
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/1191	40/18639	0.075	1.17374055415617	0.4752350884254	0.914688825706534
GO:0050997	quaternary ammonium group binding	3/1191	40/18639	0.075	1.17374055415617	0.4752350884254	0.914688825706534
GO:0140662	ATP-dependent protein folding chaperone	3/1191	40/18639	0.075	1.17374055415617	0.4752350884254	0.914688825706534
GO:0016791	phosphatase activity	18/1191	273/18639	0.0659340659340659	1.0318598278296	0.480338514647465	0.914688825706534
GO:0000030	mannosyltransferase activity	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0008139	nuclear localization sequence binding	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0015271	outward rectifier potassium channel activity	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0017025	TBP-class protein binding	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0019211	phosphatase activator activity	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0047617	fatty acyl-CoA hydrolase activity	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0120020	cholesterol transfer activity	2/1191	25/18639	0.08	1.25198992443325	0.480741679252208	0.914688825706534
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0003796	lysozyme activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0004935	adrenergic receptor activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0004955	prostaglandin receptor activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0005031	tumor necrosis factor receptor activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0005131	growth hormone receptor binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0005345	purine nucleobase transmembrane transporter activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0008190	eukaryotic initiation factor 4E binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0008239	dipeptidyl-peptidase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0008519	ammonium channel activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0015203	polyamine transmembrane transporter activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0015279	store-operated calcium channel activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0015643	toxic substance binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0016783	sulfurtransferase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0016868	intramolecular phosphotransferase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0031419	cobalamin binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0031720	haptoglobin binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0031996	thioesterase binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0035374	chondroitin sulfate binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0043422	protein kinase B binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0045322	unmethylated CpG binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0070739	protein-glutamic acid ligase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0070740	tubulin-glutamic acid ligase activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0099122	RNA polymerase II C-terminal domain binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0140135	mechanosensitive monoatomic cation channel activity	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:1905394	retromer complex binding	1/1191	10/18639	0.1	1.56498740554156	0.483394713946855	0.914688825706534
GO:0051087	protein-folding chaperone binding	9/1191	134/18639	0.0671641791044776	1.05111094402045	0.488246367516212	0.914688825706534
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/1191	41/18639	0.0731707317073171	1.14511273576212	0.491806227802986	0.914688825706534
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/1191	41/18639	0.0731707317073171	1.14511273576212	0.491806227802986	0.914688825706534
GO:0042287	MHC protein binding	3/1191	41/18639	0.0731707317073171	1.14511273576212	0.491806227802986	0.914688825706534
GO:0005126	cytokine receptor binding	18/1191	275/18639	0.0654545454545455	1.02435539271811	0.493050472759997	0.914688825706534
GO:0004197	cysteine-type endopeptidase activity	6/1191	88/18639	0.0681818181818182	1.0670368674147	0.495757165278188	0.914688825706534
GO:0016651	oxidoreductase activity, acting on NAD(P)H	6/1191	88/18639	0.0681818181818182	1.0670368674147	0.495757165278188	0.914688825706534
GO:0017171	serine hydrolase activity	13/1191	198/18639	0.0656565656565657	1.02751698343638	0.500944637935641	0.914688825706534
GO:0001637	G protein-coupled chemoattractant receptor activity	2/1191	26/18639	0.0769230769230769	1.2038364658012	0.501683271012585	0.914688825706534
GO:0004435	phosphatidylinositol phospholipase C activity	2/1191	26/18639	0.0769230769230769	1.2038364658012	0.501683271012585	0.914688825706534
GO:0004950	chemokine receptor activity	2/1191	26/18639	0.0769230769230769	1.2038364658012	0.501683271012585	0.914688825706534
GO:0008066	glutamate receptor activity	2/1191	26/18639	0.0769230769230769	1.2038364658012	0.501683271012585	0.914688825706534
GO:0016289	acyl-CoA hydrolase activity	2/1191	26/18639	0.0769230769230769	1.2038364658012	0.501683271012585	0.914688825706534
GO:0051139	metal cation:proton antiporter activity	2/1191	26/18639	0.0769230769230769	1.2038364658012	0.501683271012585	0.914688825706534
GO:0120014	phospholipid transfer activity	2/1191	26/18639	0.0769230769230769	1.2038364658012	0.501683271012585	0.914688825706534
GO:0016755	aminoacyltransferase activity	32/1191	496/18639	0.0645161290322581	1.00966929389778	0.504110347549481	0.914688825706534
GO:0140789	histone phosphatase activity	9/1191	136/18639	0.0661764705882353	1.0356534301378	0.506297780799116	0.914688825706534
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	6/1191	89/18639	0.0674157303370786	1.05504768912914	0.506895964807756	0.914688825706534
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	6/1191	89/18639	0.0674157303370786	1.05504768912914	0.506895964807756	0.914688825706534
GO:0004402	histone acetyltransferase activity	3/1191	42/18639	0.0714285714285714	1.1178481468154	0.508114357156727	0.914688825706534
GO:0008307	structural constituent of muscle	3/1191	42/18639	0.0714285714285714	1.1178481468154	0.508114357156727	0.914688825706534
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/1191	58/18639	0.0689655172413793	1.07930165899418	0.512199233929574	0.914688825706534
GO:0003697	single-stranded DNA binding	8/1191	121/18639	0.0661157024793388	1.03470241688698	0.512804377089461	0.914688825706534
GO:0003678	DNA helicase activity	5/1191	74/18639	0.0675675675675676	1.05742392266322	0.515330937633939	0.914688825706534
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0001851	complement component C3b binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0003953	NAD+ nucleosidase activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0004954	prostanoid receptor activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0008503	benzodiazepine receptor activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0008526	phosphatidylinositol transfer activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0015205	nucleobase transmembrane transporter activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0019215	intermediate filament binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0019864	IgG binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0034056	estrogen response element binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0034511	U3 snoRNA binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0035252	UDP-xylosyltransferase activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0042285	xylosyltransferase activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0043522	leucine zipper domain binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0048185	activin binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0070990	snRNP binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0140031	phosphorylation-dependent protein binding	1/1191	11/18639	0.0909090909090909	1.4227158232196	0.516422621815731	0.914688825706534
GO:0019210	kinase inhibitor activity	6/1191	90/18639	0.0666666666666667	1.04332493702771	0.517943871104094	0.914688825706534
GO:0140793	histone H2AXY142 phosphatase activity	6/1191	90/18639	0.0666666666666667	1.04332493702771	0.517943871104094	0.914688825706534
GO:0015078	proton transmembrane transporter activity	12/1191	185/18639	0.0648648648648649	1.01512696575669	0.521412366435643	0.914688825706534
GO:1901981	phosphatidylinositol phosphate binding	12/1191	185/18639	0.0648648648648649	1.01512696575669	0.521412366435643	0.914688825706534
GO:0005385	zinc ion transmembrane transporter activity	2/1191	27/18639	0.0740740740740741	1.15924993003079	0.522071265781086	0.914688825706534
GO:0008266	poly(U) RNA binding	2/1191	27/18639	0.0740740740740741	1.15924993003079	0.522071265781086	0.914688825706534
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/1191	27/18639	0.0740740740740741	1.15924993003079	0.522071265781086	0.914688825706534
GO:0008375	acetylglucosaminyltransferase activity	3/1191	43/18639	0.0697674418604651	1.09185167828481	0.52414401974291	0.914688825706534
GO:0048156	tau protein binding	3/1191	43/18639	0.0697674418604651	1.09185167828481	0.52414401974291	0.914688825706534
GO:0031593	polyubiquitin modification-dependent protein binding	4/1191	59/18639	0.0677966101694915	1.06100841053665	0.525838182185022	0.914688825706534
GO:0045309	protein phosphorylated amino acid binding	4/1191	59/18639	0.0677966101694915	1.06100841053665	0.525838182185022	0.914688825706534
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	4/1191	60/18639	0.0666666666666667	1.04332493702771	0.539289773175155	0.914688825706534
GO:0030547	signaling receptor inhibitor activity	3/1191	44/18639	0.0681818181818182	1.0670368674147	0.539881613128993	0.914688825706534
GO:0045499	chemorepellent activity	2/1191	28/18639	0.0714285714285714	1.1178481468154	0.541890862912368	0.914688825706534
GO:0046875	ephrin receptor binding	2/1191	28/18639	0.0714285714285714	1.1178481468154	0.541890862912368	0.914688825706534
GO:0046966	nuclear thyroid hormone receptor binding	2/1191	28/18639	0.0714285714285714	1.1178481468154	0.541890862912368	0.914688825706534
GO:0051959	dynein light intermediate chain binding	2/1191	28/18639	0.0714285714285714	1.1178481468154	0.541890862912368	0.914688825706534
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/1191	28/18639	0.0714285714285714	1.1178481468154	0.541890862912368	0.914688825706534
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0003995	acyl-CoA dehydrogenase activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0004126	cytidine deaminase activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0004526	ribonuclease P activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0005049	nuclear export signal receptor activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0005247	voltage-gated chloride channel activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0008179	adenylate cyclase binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0015132	prostaglandin transmembrane transporter activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0015166	polyol transmembrane transporter activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0016208	AMP binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0016801	hydrolase activity, acting on ether bonds	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0016803	ether hydrolase activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0016840	carbon-nitrogen lyase activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0017166	vinculin binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0031543	peptidyl-proline dioxygenase activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0034452	dynactin binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0035259	nuclear glucocorticoid receptor binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0070008	serine-type exopeptidase activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0097371	MDM2/MDM4 family protein binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0097677	STAT family protein binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:1990459	transferrin receptor binding	1/1191	12/18639	0.0833333333333333	1.30415617128463	0.547340630051584	0.914688825706534
GO:0140030	modification-dependent protein binding	11/1191	173/18639	0.0635838150289017	0.995078697165155	0.55131218981266	0.915872584228803
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/1191	61/18639	0.0655737704918033	1.02622124953545	0.552544697127234	0.915872584228803
GO:0004181	metallocarboxypeptidase activity	2/1191	29/18639	0.0689655172413793	1.07930165899418	0.56113140881452	0.915872584228803
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/1191	29/18639	0.0689655172413793	1.07930165899418	0.56113140881452	0.915872584228803
GO:0051861	glycolipid binding	2/1191	29/18639	0.0689655172413793	1.07930165899418	0.56113140881452	0.915872584228803
GO:0106222	lncRNA binding	2/1191	29/18639	0.0689655172413793	1.07930165899418	0.56113140881452	0.915872584228803
GO:0019199	transmembrane receptor protein kinase activity	5/1191	78/18639	0.0641025641025641	1.00319705483433	0.56279551838897	0.915872584228803
GO:0004180	carboxypeptidase activity	3/1191	46/18639	0.0652173913043478	1.0206439601358	0.570434869547752	0.915872584228803
GO:0030291	protein serine/threonine kinase inhibitor activity	3/1191	46/18639	0.0652173913043478	1.0206439601358	0.570434869547752	0.915872584228803
GO:0019787	ubiquitin-like protein transferase activity	30/1191	479/18639	0.0626304801670146	0.980159126643984	0.573123511661731	0.915872584228803
GO:0004252	serine-type endopeptidase activity	11/1191	176/18639	0.0625	0.978117128463476	0.5746337722229	0.915872584228803
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0004465	lipoprotein lipase activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0005035	death receptor activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0005542	folic acid binding	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0043560	insulin receptor substrate binding	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0045159	myosin II binding	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0051011	microtubule minus-end binding	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0070123	transforming growth factor beta receptor activity, type III	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0071714	icosanoid transmembrane transporter activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0071837	HMG box domain binding	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0140333	glycerophospholipid flippase activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0140666	annealing activity	1/1191	13/18639	0.0769230769230769	1.2038364658012	0.576283417919119	0.915872584228803
GO:0005200	structural constituent of cytoskeleton	7/1191	112/18639	0.0625	0.978117128463476	0.579429922360581	0.915872584228803
GO:0001965	G-protein alpha-subunit binding	2/1191	30/18639	0.0666666666666667	1.04332493702771	0.579785928187131	0.915872584228803
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/1191	30/18639	0.0666666666666667	1.04332493702771	0.579785928187131	0.915872584228803
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/1191	30/18639	0.0666666666666667	1.04332493702771	0.579785928187131	0.915872584228803
GO:0008187	poly-pyrimidine tract binding	2/1191	30/18639	0.0666666666666667	1.04332493702771	0.579785928187131	0.915872584228803
GO:0016769	transferase activity, transferring nitrogenous groups	2/1191	30/18639	0.0666666666666667	1.04332493702771	0.579785928187131	0.915872584228803
GO:0033612	receptor serine/threonine kinase binding	2/1191	30/18639	0.0666666666666667	1.04332493702771	0.579785928187131	0.915872584228803
GO:0061630	ubiquitin protein ligase activity	22/1191	353/18639	0.0623229461756374	0.975346258411172	0.580246467196811	0.915872584228803
GO:0046982	protein heterodimerization activity	23/1191	369/18639	0.0623306233062331	0.975466404538101	0.580449510596955	0.915872584228803
GO:0016407	acetyltransferase activity	6/1191	96/18639	0.0625	0.978117128463476	0.581980587920526	0.915872584228803
GO:0043495	protein-membrane adaptor activity	3/1191	47/18639	0.0638297872340425	0.998928131196742	0.585231723157202	0.915872584228803
GO:0061733	protein-lysine-acetyltransferase activity	3/1191	47/18639	0.0638297872340425	0.998928131196742	0.585231723157202	0.915872584228803
GO:0035591	signaling adaptor activity	8/1191	129/18639	0.062015503875969	0.970534825142054	0.586535500636616	0.915872584228803
GO:0008236	serine-type peptidase activity	12/1191	194/18639	0.0618556701030928	0.968033446726739	0.588791516522705	0.915872584228803
GO:0061659	ubiquitin-like protein ligase activity	23/1191	372/18639	0.0618279569892473	0.967599739985374	0.596336220738687	0.915872584228803
GO:0005164	tumor necrosis factor receptor binding	2/1191	31/18639	0.0645161290322581	1.00966929389778	0.597850698152214	0.915872584228803
GO:0016411	acylglycerol O-acyltransferase activity	2/1191	31/18639	0.0645161290322581	1.00966929389778	0.597850698152214	0.915872584228803
GO:0016878	acid-thiol ligase activity	2/1191	31/18639	0.0645161290322581	1.00966929389778	0.597850698152214	0.915872584228803
GO:0072349	modified amino acid transmembrane transporter activity	2/1191	31/18639	0.0645161290322581	1.00966929389778	0.597850698152214	0.915872584228803
GO:0032266	phosphatidylinositol-3-phosphate binding	3/1191	48/18639	0.0625	0.978117128463476	0.599698696634787	0.915872584228803
GO:0038187	pattern recognition receptor activity	3/1191	48/18639	0.0625	0.978117128463476	0.599698696634787	0.915872584228803
GO:0008170	N-methyltransferase activity	6/1191	98/18639	0.0612244897959184	0.958155554413201	0.602342841788875	0.915872584228803
GO:0005344	oxygen carrier activity	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0008195	phosphatidate phosphatase activity	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0019763	immunoglobulin receptor activity	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0019992	diacylglycerol binding	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0034236	protein kinase A catalytic subunit binding	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0042043	neurexin family protein binding	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0043176	amine binding	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0046030	inositol trisphosphate phosphatase activity	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0061783	peptidoglycan muralytic activity	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0098599	palmitoyl hydrolase activity	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:1901612	cardiolipin binding	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:1990825	sequence-specific mRNA binding	1/1191	14/18639	0.0714285714285714	1.1178481468154	0.603377074595718	0.915872584228803
GO:0017124	SH3 domain binding	7/1191	115/18639	0.0608695652173913	0.952601029460081	0.607669403501376	0.915872584228803
GO:0003730	mRNA 3'-UTR binding	16/1191	262/18639	0.0610687022900763	0.955717499567366	0.611305150065111	0.915872584228803
GO:0005004	GPI-linked ephrin receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0005008	hepatocyte growth factor receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0005009	insulin receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0005011	macrophage colony-stimulating factor receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0005020	stem cell factor receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0008288	boss receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0035254	glutamate receptor binding	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0036332	placental growth factor receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0038062	protein tyrosine kinase collagen receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0060175	brain-derived neurotrophic factor receptor activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0060590	ATPase regulator activity	3/1191	49/18639	0.0612244897959184	0.958155554413201	0.61383000782634	0.915872584228803
GO:0005085	guanyl-nucleotide exchange factor activity	14/1191	230/18639	0.0608695652173913	0.952601029460081	0.613846433245207	0.915872584228803
GO:0120015	sterol transfer activity	2/1191	32/18639	0.0625	0.978117128463476	0.615324861717482	0.915872584228803
GO:0140142	nucleocytoplasmic carrier activity	2/1191	32/18639	0.0625	0.978117128463476	0.615324861717482	0.915872584228803
GO:0016741	transferase activity, transferring one-carbon groups	13/1191	215/18639	0.0604651162790698	0.946271454513502	0.622210571942379	0.915872584228803
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4/1191	67/18639	0.0597014925373134	0.934320839129291	0.627529763875069	0.915872584228803
GO:0005006	epidermal growth factor receptor activity	3/1191	50/18639	0.06	0.938992443324937	0.627621157026224	0.915872584228803
GO:0005007	fibroblast growth factor receptor activity	3/1191	50/18639	0.06	0.938992443324937	0.627621157026224	0.915872584228803
GO:0005017	platelet-derived growth factor receptor activity	3/1191	50/18639	0.06	0.938992443324937	0.627621157026224	0.915872584228803
GO:0005019	platelet-derived growth factor beta-receptor activity	3/1191	50/18639	0.06	0.938992443324937	0.627621157026224	0.915872584228803
GO:0001216	DNA-binding transcription activator activity	30/1191	491/18639	0.0610997963340122	0.956204117438836	0.628362515939165	0.915872584228803
GO:0004559	alpha-mannosidase activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0004953	icosanoid receptor activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0005041	low-density lipoprotein particle receptor activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0008242	omega peptidase activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0010181	FMN binding	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0015250	water channel activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0015929	hexosaminidase activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0031386	protein tag activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0033130	acetylcholine receptor binding	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0034483	heparan sulfate sulfotransferase activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0050780	dopamine receptor binding	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0120283	protein serine/threonine kinase binding	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0141047	molecular tag activity	1/1191	15/18639	0.0666666666666667	1.04332493702771	0.628739646630965	0.915872584228803
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	10/1191	167/18639	0.0598802395209581	0.937118206911115	0.629969603999955	0.915872584228803
GO:0016874	ligase activity	10/1191	167/18639	0.0598802395209581	0.937118206911115	0.629969603999955	0.915872584228803
GO:0071889	14-3-3 protein binding	2/1191	33/18639	0.0606060606060606	0.948477215479734	0.6322100772908	0.916745611428164
GO:0140416	transcription regulator inhibitor activity	2/1191	33/18639	0.0606060606060606	0.948477215479734	0.6322100772908	0.916745611428164
GO:0015297	antiporter activity	8/1191	135/18639	0.0592592592592593	0.927399944024629	0.638123256364181	0.922218059807031
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	4/1191	68/18639	0.0588235294117647	0.920580826789154	0.6392173208445	0.922218059807031
GO:0005010	insulin-like growth factor receptor activity	3/1191	51/18639	0.0588235294117647	0.920580826789154	0.641068838183269	0.922218059807031
GO:0005021	vascular endothelial growth factor receptor activity	3/1191	51/18639	0.0588235294117647	0.920580826789154	0.641068838183269	0.922218059807031
GO:0005030	neurotrophin receptor activity	3/1191	51/18639	0.0588235294117647	0.920580826789154	0.641068838183269	0.922218059807031
GO:0005272	sodium channel activity	3/1191	51/18639	0.0588235294117647	0.920580826789154	0.641068838183269	0.922218059807031
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1191	34/18639	0.0588235294117647	0.920580826789154	0.648510201222825	0.922218059807031
GO:0016831	carboxy-lyase activity	2/1191	34/18639	0.0588235294117647	0.920580826789154	0.648510201222825	0.922218059807031
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/1191	34/18639	0.0588235294117647	0.920580826789154	0.648510201222825	0.922218059807031
GO:0019825	oxygen binding	2/1191	34/18639	0.0588235294117647	0.920580826789154	0.648510201222825	0.922218059807031
GO:0030332	cyclin binding	2/1191	34/18639	0.0588235294117647	0.920580826789154	0.648510201222825	0.922218059807031
GO:0051427	hormone receptor binding	2/1191	34/18639	0.0588235294117647	0.920580826789154	0.648510201222825	0.922218059807031
GO:0000062	fatty-acyl-CoA binding	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0005149	interleukin-1 receptor binding	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0015923	mannosidase activity	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0017070	U6 snRNA binding	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0043023	ribosomal large subunit binding	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/1191	16/18639	0.0625	0.978117128463476	0.652481650543257	0.922218059807031
GO:0004842	ubiquitin-protein transferase activity	27/1191	449/18639	0.0601336302895323	0.941083740526106	0.657394845261604	0.927989188134436
GO:0008168	methyltransferase activity	12/1191	204/18639	0.0588235294117647	0.920580826789154	0.658350599458572	0.928166418908807
GO:0016229	steroid dehydrogenase activity	2/1191	35/18639	0.0571428571428571	0.894278517452321	0.664231000593481	0.929704861515078
GO:0061631	ubiquitin conjugating enzyme activity	2/1191	35/18639	0.0571428571428571	0.894278517452321	0.664231000593481	0.929704861515078
GO:0140566	histone reader activity	2/1191	35/18639	0.0571428571428571	0.894278517452321	0.664231000593481	0.929704861515078
GO:0005096	GTPase activator activity	16/1191	271/18639	0.0590405904059041	0.923977804009778	0.664852485845893	0.929704861515078
GO:0005003	ephrin receptor activity	3/1191	53/18639	0.0566037735849057	0.885841927665035	0.666926027670029	0.929704861515078
GO:0005005	transmembrane-ephrin receptor activity	3/1191	53/18639	0.0566037735849057	0.885841927665035	0.666926027670029	0.929704861515078
GO:0034212	protein N-acetyltransferase activity	3/1191	53/18639	0.0566037735849057	0.885841927665035	0.666926027670029	0.929704861515078
GO:0038064	collagen receptor activity	3/1191	53/18639	0.0566037735849057	0.885841927665035	0.666926027670029	0.929704861515078
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/1191	53/18639	0.0566037735849057	0.885841927665035	0.666926027670029	0.929704861515078
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	29/1191	484/18639	0.0599173553719008	0.937699065303828	0.668622223430263	0.930113348950582
GO:0005244	voltage-gated monoatomic ion channel activity	10/1191	173/18639	0.0578034682080925	0.904616997422868	0.673711238698946	0.930113348950582
GO:0004549	tRNA-specific ribonuclease activity	1/1191	17/18639	0.0588235294117647	0.920580826789154	0.674706552771844	0.930113348950582
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/1191	17/18639	0.0588235294117647	0.920580826789154	0.674706552771844	0.930113348950582
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/1191	17/18639	0.0588235294117647	0.920580826789154	0.674706552771844	0.930113348950582
GO:0017110	nucleoside diphosphate phosphatase activity	1/1191	17/18639	0.0588235294117647	0.920580826789154	0.674706552771844	0.930113348950582
GO:0036041	long-chain fatty acid binding	1/1191	17/18639	0.0588235294117647	0.920580826789154	0.674706552771844	0.930113348950582
GO:0070403	NAD+ binding	1/1191	17/18639	0.0588235294117647	0.920580826789154	0.674706552771844	0.930113348950582
GO:1901567	fatty acid derivative binding	1/1191	17/18639	0.0588235294117647	0.920580826789154	0.674706552771844	0.930113348950582
GO:0004033	aldo-keto reductase (NADPH) activity	2/1191	36/18639	0.0555555555555556	0.86943744752309	0.679379893678458	0.935402365926744
GO:0022832	voltage-gated channel activity	10/1191	175/18639	0.0571428571428571	0.894278517452321	0.687593174221073	0.942523082316271
GO:0022804	active transmembrane transporter activity	27/1191	457/18639	0.0590809628008753	0.924609626906393	0.692648777029391	0.942523082316271
GO:0022829	wide pore channel activity	2/1191	37/18639	0.0540540540540541	0.845939138130574	0.693965715735645	0.942523082316271
GO:0043539	protein serine/threonine kinase activator activity	4/1191	73/18639	0.0547945205479452	0.857527345502226	0.693982156225151	0.942523082316271
GO:0000400	four-way junction DNA binding	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0004706	JUN kinase kinase kinase activity	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0005372	water transmembrane transporter activity	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0015280	ligand-gated sodium channel activity	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0016854	racemase and epimerase activity	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0022851	GABA-gated chloride ion channel activity	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:1901611	phosphatidylglycerol binding	1/1191	18/18639	0.0555555555555556	0.86943744752309	0.695511219061649	0.942523082316271
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	5/1191	91/18639	0.0549450549450549	0.859883189858001	0.698529497821582	0.945467286397735
GO:0022843	voltage-gated monoatomic cation channel activity	8/1191	143/18639	0.0559440559440559	0.875517429673601	0.700915345483208	0.947549402962788
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/1191	56/18639	0.0535714285714286	0.838386110111551	0.703112495861159	0.948226502259078
GO:0170055	lipid transmembrane transporter activity	3/1191	56/18639	0.0535714285714286	0.838386110111551	0.703112495861159	0.948226502259078
GO:0005319	lipid transporter activity	10/1191	178/18639	0.0561797752808989	0.879206407607619	0.707730709283102	0.950481239931914
GO:0004519	endonuclease activity	7/1191	127/18639	0.0551181102362205	0.862591483369365	0.709628553759844	0.950481239931914
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0004890	GABA-A receptor activity	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0015245	fatty acid transmembrane transporter activity	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0016918	retinal binding	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0022821	solute:potassium antiporter activity	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0042577	lipid phosphatase activity	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0070003	threonine-type peptidase activity	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0097001	ceramide binding	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0120227	acyl-CoA binding	1/1191	19/18639	0.0526315789473684	0.82367758186398	0.714986335226064	0.950481239931914
GO:0042393	histone binding	14/1191	247/18639	0.0566801619433198	0.887037395853517	0.716842641521667	0.950767421176774
GO:0000217	DNA secondary structure binding	2/1191	39/18639	0.0512820512820513	0.802557643867468	0.721489327466215	0.950767421176774
GO:0017116	single-stranded DNA helicase activity	3/1191	58/18639	0.0517241379310345	0.809476244245635	0.725520191450178	0.950767421176774
GO:0015081	sodium ion transmembrane transporter activity	9/1191	164/18639	0.0548780487804878	0.858834551821589	0.727917427449464	0.950767421176774
GO:0001972	retinoic acid binding	1/1191	20/18639	0.05	0.782493702770781	0.733216801109295	0.950767421176774
GO:0030627	pre-mRNA 5'-splice site binding	1/1191	20/18639	0.05	0.782493702770781	0.733216801109295	0.950767421176774
GO:0052745	inositol phosphate phosphatase activity	1/1191	20/18639	0.05	0.782493702770781	0.733216801109295	0.950767421176774
GO:0061608	nuclear import signal receptor activity	1/1191	20/18639	0.05	0.782493702770781	0.733216801109295	0.950767421176774
GO:0005125	cytokine activity	13/1191	234/18639	0.0555555555555556	0.86943744752309	0.738141920379183	0.950767421176774
GO:0004896	cytokine receptor activity	5/1191	96/18639	0.0520833333333333	0.815097607052897	0.742205786968839	0.950767421176774
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/1191	60/18639	0.05	0.782493702770781	0.746582056092388	0.950767421176774
GO:0001530	lipopolysaccharide binding	2/1191	41/18639	0.0487804878048781	0.763408490508079	0.74689335120154	0.950767421176774
GO:0004812	aminoacyl-tRNA ligase activity	2/1191	41/18639	0.0487804878048781	0.763408490508079	0.74689335120154	0.950767421176774
GO:0008137	NADH dehydrogenase (ubiquinone) activity	2/1191	41/18639	0.0487804878048781	0.763408490508079	0.74689335120154	0.950767421176774
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/1191	41/18639	0.0487804878048781	0.763408490508079	0.74689335120154	0.950767421176774
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:0005248	voltage-gated sodium channel activity	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:0008373	sialyltransferase activity	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:0051428	peptide hormone receptor binding	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:0072542	protein phosphatase activator activity	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:0140312	cargo adaptor activity	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:1904047	S-adenosyl-L-methionine binding	1/1191	21/18639	0.0476190476190476	0.745232097876934	0.750282099453934	0.950767421176774
GO:0015370	solute:sodium symporter activity	4/1191	79/18639	0.0506329113924051	0.792398686350158	0.751517058984958	0.950767421176774
GO:0030695	GTPase regulator activity	28/1191	489/18639	0.0572597137014315	0.896107307876559	0.754520498810295	0.950767421176774
GO:0060589	nucleoside-triphosphatase regulator activity	28/1191	490/18639	0.0571428571428571	0.894278517452321	0.758191590728926	0.950767421176774
GO:0015294	solute:monoatomic cation symporter activity	6/1191	116/18639	0.0517241379310345	0.809476244245635	0.758612155132404	0.950767421176774
GO:0004520	DNA endonuclease activity	2/1191	42/18639	0.0476190476190476	0.745232097876934	0.758832300903781	0.950767421176774
GO:0046906	tetrapyrrole binding	8/1191	152/18639	0.0526315789473684	0.82367758186398	0.762604434438949	0.950767421176774
GO:0008234	cysteine-type peptidase activity	10/1191	187/18639	0.053475935828877	0.836891660717413	0.763046288381405	0.950767421176774
GO:0004407	histone deacetylase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0005243	gap junction channel activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0008093	cytoskeletal anchor activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0008970	phospholipase A1 activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0031683	G-protein beta/gamma-subunit complex binding	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0032931	histone H3K56 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0033558	protein lysine deacetylase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0043992	histone H3K9 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0043993	histone H3K18 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0043994	histone H3K23 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0043999	histone H2AK5 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0044012	histone H2AK9 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0044014	histone H2BK5 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0044015	histone H2BK12 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0044016	histone H3K4 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0044017	histone H3K27 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0044018	histone H3K36 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0046972	histone H4K16 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0140908	histone H3K122 acetyltransferase activity	1/1191	22/18639	0.0454545454545455	0.711357911609801	0.766256641271012	0.950767421176774
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/1191	43/18639	0.0465116279069767	0.72790111885654	0.770280509740897	0.950767421176774
GO:0022853	active monoatomic ion transmembrane transporter activity	6/1191	118/18639	0.0508474576271186	0.795756307902489	0.772797541404459	0.950767421176774
GO:0016779	nucleotidyltransferase activity	7/1191	136/18639	0.0514705882352941	0.80550822344051	0.773426999440029	0.950767421176774
GO:0044325	transmembrane transporter binding	7/1191	136/18639	0.0514705882352941	0.80550822344051	0.773426999440029	0.950767421176774
GO:0005507	copper ion binding	3/1191	63/18639	0.0476190476190476	0.745232097876934	0.775726547841703	0.950767421176774
GO:0022824	transmitter-gated monoatomic ion channel activity	3/1191	63/18639	0.0476190476190476	0.745232097876934	0.775726547841703	0.950767421176774
GO:0022835	transmitter-gated channel activity	3/1191	63/18639	0.0476190476190476	0.745232097876934	0.775726547841703	0.950767421176774
GO:1901682	sulfur compound transmembrane transporter activity	3/1191	63/18639	0.0476190476190476	0.745232097876934	0.775726547841703	0.950767421176774
GO:0003887	DNA-directed DNA polymerase activity	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0004602	glutathione peroxidase activity	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0005212	structural constituent of eye lens	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0008171	O-methyltransferase activity	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0016917	GABA receptor activity	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0042171	lysophosphatidic acid acyltransferase activity	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0043274	phospholipase binding	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0044013	histone H2B acetyltransferase activity	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0070577	lysine-acetylated histone binding	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0071617	lysophospholipid acyltransferase activity	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0099186	structural constituent of postsynapse	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0140102	catalytic activity, acting on a rRNA	1/1191	23/18639	0.0434782608695652	0.680429306757201	0.781210089208178	0.950767421176774
GO:0003954	NADH dehydrogenase activity	2/1191	44/18639	0.0454545454545455	0.711357911609801	0.781251885770034	0.950767421176774
GO:0016790	thiolester hydrolase activity	2/1191	44/18639	0.0454545454545455	0.711357911609801	0.781251885770034	0.950767421176774
GO:0004536	DNA nuclease activity	3/1191	64/18639	0.046875	0.733587846347607	0.784809032477658	0.950767421176774
GO:0004518	nuclease activity	11/1191	209/18639	0.0526315789473684	0.82367758186398	0.787730858371255	0.950767421176774
GO:0008009	chemokine activity	2/1191	45/18639	0.0444444444444444	0.695549958018472	0.791760564561133	0.950767421176774
GO:0042605	peptide antigen binding	2/1191	45/18639	0.0444444444444444	0.695549958018472	0.791760564561133	0.950767421176774
GO:0046915	transition metal ion transmembrane transporter activity	2/1191	45/18639	0.0444444444444444	0.695549958018472	0.791760564561133	0.950767421176774
GO:0140101	catalytic activity, acting on a tRNA	7/1191	139/18639	0.0503597122302158	0.788123153869851	0.792234371905867	0.950767421176774
GO:0120013	lipid transfer activity	3/1191	65/18639	0.0461538461538462	0.722301879480721	0.793584874324905	0.950767421176774
GO:0160215	deacylase activity	3/1191	65/18639	0.0461538461538462	0.722301879480721	0.793584874324905	0.950767421176774
GO:0001664	G protein-coupled receptor binding	16/1191	297/18639	0.0538720538720539	0.843090858204208	0.794411154402524	0.950767421176774
GO:0004806	triacylglycerol lipase activity	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0015149	hexose transmembrane transporter activity	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0035035	histone acetyltransferase binding	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0043998	histone H2A acetyltransferase activity	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0055056	D-glucose transmembrane transporter activity	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0070300	phosphatidic acid binding	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0140612	DNA damage sensor activity	1/1191	24/18639	0.0416666666666667	0.652078085642317	0.795207660316529	0.950767421176774
GO:0004722	protein serine/threonine phosphatase activity	5/1191	103/18639	0.0485436893203883	0.759702624049302	0.795252098651083	0.950767421176774
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	12/1191	229/18639	0.0524017467248908	0.820080736528329	0.800041375676758	0.950767421176774
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/1191	46/18639	0.0434782608695652	0.680429306757201	0.801820823425377	0.950767421176774
GO:0001848	complement binding	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0003707	nuclear steroid receptor activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0005537	D-mannose binding	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0008483	transaminase activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0015645	fatty acid ligase activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0015662	P-type ion transporter activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0019707	protein-cysteine S-acyltransferase activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0042974	nuclear retinoic acid receptor binding	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0120515	fatty acid-CoA ligase activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0140358	P-type transmembrane transporter activity	1/1191	25/18639	0.04	0.625994962216625	0.808310409527543	0.950767421176774
GO:0020037	heme binding	7/1191	142/18639	0.0492957746478873	0.771472664703587	0.809840164155422	0.950767421176774
GO:0016500	protein-hormone receptor activity	3/1191	67/18639	0.0447761194029851	0.700740629346968	0.810241302626126	0.950767421176774
GO:0140098	catalytic activity, acting on RNA	21/1191	387/18639	0.0542635658914729	0.849217971999297	0.811270082027999	0.950767421176774
GO:0005504	fatty acid binding	2/1191	47/18639	0.0425531914893617	0.665952087464494	0.811447005659518	0.950767421176774
GO:0061749	forked DNA-dependent helicase activity	2/1191	47/18639	0.0425531914893617	0.665952087464494	0.811447005659518	0.950767421176774
GO:1990518	single-stranded 3'-5' DNA helicase activity	2/1191	47/18639	0.0425531914893617	0.665952087464494	0.811447005659518	0.950767421176774
GO:0030145	manganese ion binding	3/1191	68/18639	0.0441176470588235	0.690435620091866	0.818134717169893	0.950767421176774
GO:0008143	poly(A) binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0008157	protein phosphatase 1 binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0008198	ferrous iron binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0015145	monosaccharide transmembrane transporter activity	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0030247	polysaccharide binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0030507	spectrin binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0034237	protein kinase A regulatory subunit binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0043548	phosphatidylinositol 3-kinase binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0052742	phosphatidylinositol kinase activity	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0097602	cullin family protein binding	1/1191	26/18639	0.0384615384615385	0.601918232900601	0.820575495068141	0.950767421176774
GO:0009378	four-way junction helicase activity	2/1191	48/18639	0.0416666666666667	0.652078085642317	0.820653453877985	0.950767421176774
GO:0036121	double-stranded DNA helicase activity	2/1191	48/18639	0.0416666666666667	0.652078085642317	0.820653453877985	0.950767421176774
GO:0043138	3'-5' DNA helicase activity	2/1191	48/18639	0.0416666666666667	0.652078085642317	0.820653453877985	0.950767421176774
GO:0002039	p53 binding	3/1191	69/18639	0.0434782608695652	0.680429306757201	0.825747077351027	0.952138265450896
GO:0098960	postsynaptic neurotransmitter receptor activity	3/1191	69/18639	0.0434782608695652	0.680429306757201	0.825747077351027	0.952138265450896
GO:0004843	cysteine-type deubiquitinase activity	5/1191	108/18639	0.0462962962962963	0.724531206269242	0.82760966772612	0.952138265450896
GO:0019783	ubiquitin-like protein peptidase activity	6/1191	127/18639	0.047244094488189	0.739364128602313	0.828947094877748	0.952138265450896
GO:0015293	symporter activity	7/1191	146/18639	0.0479452054794521	0.750336427314447	0.83149681166246	0.952138265450896
GO:0004364	glutathione transferase activity	1/1191	27/18639	0.037037037037037	0.579624965015393	0.832056426963797	0.952138265450896
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/1191	27/18639	0.037037037037037	0.579624965015393	0.832056426963797	0.952138265450896
GO:0008395	steroid hydroxylase activity	1/1191	27/18639	0.037037037037037	0.579624965015393	0.832056426963797	0.952138265450896
GO:0015252	proton channel activity	1/1191	27/18639	0.037037037037037	0.579624965015393	0.832056426963797	0.952138265450896
GO:0016405	CoA-ligase activity	1/1191	27/18639	0.037037037037037	0.579624965015393	0.832056426963797	0.952138265450896
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/1191	27/18639	0.037037037037037	0.579624965015393	0.832056426963797	0.952138265450896
GO:0035255	ionotropic glutamate receptor binding	1/1191	27/18639	0.037037037037037	0.579624965015393	0.832056426963797	0.952138265450896
GO:0015103	inorganic anion transmembrane transporter activity	8/1191	165/18639	0.0484848484848485	0.758781772383788	0.834762628268023	0.954258301026227
GO:0032813	tumor necrosis factor receptor superfamily binding	2/1191	50/18639	0.04	0.625994962216625	0.837864172188814	0.954483601600813
GO:0005242	inward rectifier potassium channel activity	1/1191	28/18639	0.0357142857142857	0.558924073407701	0.842803299706442	0.954483601600813
GO:0016866	intramolecular transferase activity	1/1191	28/18639	0.0357142857142857	0.558924073407701	0.842803299706442	0.954483601600813
GO:0019789	SUMO transferase activity	1/1191	28/18639	0.0357142857142857	0.558924073407701	0.842803299706442	0.954483601600813
GO:0036408	histone H3K14 acetyltransferase activity	1/1191	28/18639	0.0357142857142857	0.558924073407701	0.842803299706442	0.954483601600813
GO:0046625	sphingolipid binding	1/1191	28/18639	0.0357142857142857	0.558924073407701	0.842803299706442	0.954483601600813
GO:0051119	sugar transmembrane transporter activity	1/1191	28/18639	0.0357142857142857	0.558924073407701	0.842803299706442	0.954483601600813
GO:0016798	hydrolase activity, acting on glycosyl bonds	6/1191	130/18639	0.0461538461538462	0.722301879480721	0.844998727381883	0.954483601600813
GO:0005048	signal sequence binding	2/1191	51/18639	0.0392156862745098	0.613720551192769	0.845896634801285	0.954483601600813
GO:0016830	carbon-carbon lyase activity	2/1191	51/18639	0.0392156862745098	0.613720551192769	0.845896634801285	0.954483601600813
GO:0042379	chemokine receptor binding	3/1191	72/18639	0.0416666666666667	0.652078085642317	0.84696580662709	0.954483601600813
GO:0046873	metal ion transmembrane transporter activity	24/1191	450/18639	0.0533333333333333	0.834659949622166	0.847979587371633	0.954483601600813
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/1191	29/18639	0.0344827586206897	0.53965082949709	0.85286301009544	0.954483601600813
GO:0010484	histone H3 acetyltransferase activity	1/1191	29/18639	0.0344827586206897	0.53965082949709	0.85286301009544	0.954483601600813
GO:0016417	S-acyltransferase activity	1/1191	29/18639	0.0344827586206897	0.53965082949709	0.85286301009544	0.954483601600813
GO:0035250	UDP-galactosyltransferase activity	1/1191	29/18639	0.0344827586206897	0.53965082949709	0.85286301009544	0.954483601600813
GO:0097472	cyclin-dependent protein kinase activity	1/1191	29/18639	0.0344827586206897	0.53965082949709	0.85286301009544	0.954483601600813
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/1191	73/18639	0.0410958904109589	0.643145509126669	0.853522248787173	0.954483601600813
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/1191	52/18639	0.0384615384615385	0.601918232900601	0.853565666075993	0.954483601600813
GO:0030159	signaling receptor complex adaptor activity	2/1191	52/18639	0.0384615384615385	0.601918232900601	0.853565666075993	0.954483601600813
GO:0046943	carboxylic acid transmembrane transporter activity	9/1191	188/18639	0.0478723404255319	0.749196098397556	0.855677472597591	0.954483601600813
GO:0005342	organic acid transmembrane transporter activity	9/1191	189/18639	0.0476190476190476	0.745232097876934	0.859747124386338	0.954483601600813
GO:0035064	methylated histone binding	3/1191	74/18639	0.0405405405405405	0.63445435359793	0.859832028428004	0.954483601600813
GO:0017046	peptide hormone binding	2/1191	53/18639	0.0377358490566038	0.590561285110023	0.860884867582109	0.954483601600813
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/1191	53/18639	0.0377358490566038	0.590561285110023	0.860884867582109	0.954483601600813
GO:0031624	ubiquitin conjugating enzyme binding	1/1191	30/18639	0.0333333333333333	0.521662468513854	0.862279461195726	0.954483601600813
GO:0043995	histone H4K5 acetyltransferase activity	1/1191	30/18639	0.0333333333333333	0.521662468513854	0.862279461195726	0.954483601600813
GO:0043996	histone H4K8 acetyltransferase activity	1/1191	30/18639	0.0333333333333333	0.521662468513854	0.862279461195726	0.954483601600813
GO:0043997	histone H4K12 acetyltransferase activity	1/1191	30/18639	0.0333333333333333	0.521662468513854	0.862279461195726	0.954483601600813
GO:0048019	receptor antagonist activity	1/1191	30/18639	0.0333333333333333	0.521662468513854	0.862279461195726	0.954483601600813
GO:0070566	adenylyltransferase activity	1/1191	30/18639	0.0333333333333333	0.521662468513854	0.862279461195726	0.954483601600813
GO:0098918	structural constituent of synapse	1/1191	30/18639	0.0333333333333333	0.521662468513854	0.862279461195726	0.954483601600813
GO:0101005	deubiquitinase activity	5/1191	115/18639	0.0434782608695652	0.680429306757201	0.865800732023141	0.957433450446955
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/1191	54/18639	0.037037037037037	0.579624965015393	0.867867588111934	0.958770714929983
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/1191	31/18639	0.032258064516129	0.504834646948891	0.871093753297176	0.960201585305723
GO:0005452	solute:inorganic anion antiporter activity	1/1191	31/18639	0.032258064516129	0.504834646948891	0.871093753297176	0.960201585305723
GO:0140034	methylation-dependent protein binding	3/1191	76/18639	0.0394736842105263	0.617758186397985	0.871739364119238	0.960201585305723
GO:0008374	O-acyltransferase activity	2/1191	55/18639	0.0363636363636364	0.569086329287841	0.87452690044252	0.960687180580687
GO:0008378	galactosyltransferase activity	1/1191	32/18639	0.03125	0.489058564231738	0.879344362702973	0.960687180580687
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/1191	32/18639	0.03125	0.489058564231738	0.879344362702973	0.960687180580687
GO:0070717	poly-purine tract binding	1/1191	32/18639	0.03125	0.489058564231738	0.879344362702973	0.960687180580687
GO:0005249	voltage-gated potassium channel activity	4/1191	98/18639	0.0408163265306122	0.638770369608801	0.87961469461016	0.960687180580687
GO:0030170	pyridoxal phosphate binding	2/1191	56/18639	0.0357142857142857	0.558924073407701	0.880875582093682	0.960687180580687
GO:0015291	secondary active transmembrane transporter activity	14/1191	287/18639	0.0487804878048781	0.763408490508079	0.883775933878459	0.960687180580687
GO:0140767	enzyme-substrate adaptor activity	6/1191	139/18639	0.0431654676258993	0.675534131888444	0.885917940131808	0.960687180580687
GO:0070279	vitamin B6 binding	2/1191	57/18639	0.0350877192982456	0.54911838790932	0.886926099667277	0.960687180580687
GO:0019239	deaminase activity	1/1191	33/18639	0.0303030303030303	0.474238607739867	0.887067309122103	0.960687180580687
GO:0033293	monocarboxylic acid binding	3/1191	79/18639	0.0379746835443038	0.594299014762618	0.887922986316365	0.960687180580687
GO:0015079	potassium ion transmembrane transporter activity	7/1191	160/18639	0.04375	0.684681989924433	0.892260902796987	0.960687180580687
GO:0008175	tRNA methyltransferase activity	1/1191	34/18639	0.0294117647058824	0.460290413394577	0.894296312391779	0.960687180580687
GO:0008376	acetylgalactosaminyltransferase activity	1/1191	34/18639	0.0294117647058824	0.460290413394577	0.894296312391779	0.960687180580687
GO:0015020	glucuronosyltransferase activity	1/1191	34/18639	0.0294117647058824	0.460290413394577	0.894296312391779	0.960687180580687
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/1191	34/18639	0.0294117647058824	0.460290413394577	0.894296312391779	0.960687180580687
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/1191	34/18639	0.0294117647058824	0.460290413394577	0.894296312391779	0.960687180580687
GO:0090482	vitamin transmembrane transporter activity	1/1191	34/18639	0.0294117647058824	0.460290413394577	0.894296312391779	0.960687180580687
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	5/1191	122/18639	0.040983606557377	0.641388280959656	0.896605748600323	0.960687180580687
GO:0033192	calmodulin-dependent protein phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:0140791	histone H2AXS140 phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:1990439	MAP kinase serine/threonine phosphatase activity	3/1191	81/18639	0.037037037037037	0.579624965015393	0.897672634605614	0.960687180580687
GO:0015459	potassium channel regulator activity	2/1191	59/18639	0.0338983050847458	0.530504205268326	0.898180882510116	0.960687180580687
GO:0070888	E-box binding	2/1191	59/18639	0.0338983050847458	0.530504205268326	0.898180882510116	0.960687180580687
GO:0000175	3'-5'-RNA exonuclease activity	1/1191	35/18639	0.0285714285714286	0.44713925872616	0.901062939209375	0.960687180580687
GO:0005154	epidermal growth factor receptor binding	1/1191	35/18639	0.0285714285714286	0.44713925872616	0.901062939209375	0.960687180580687
GO:0010485	histone H4 acetyltransferase activity	1/1191	35/18639	0.0285714285714286	0.44713925872616	0.901062939209375	0.960687180580687
GO:0034061	DNA polymerase activity	1/1191	35/18639	0.0285714285714286	0.44713925872616	0.901062939209375	0.960687180580687
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	3/1191	82/18639	0.0365853658536585	0.572556367881059	0.902255402155385	0.960687180580687
GO:0033549	MAP kinase phosphatase activity	3/1191	82/18639	0.0365853658536585	0.572556367881059	0.902255402155385	0.960687180580687
GO:0005267	potassium channel activity	5/1191	124/18639	0.0403225806451613	0.631043308686114	0.904199717513639	0.961582517431725
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	3/1191	83/18639	0.036144578313253	0.565658098388516	0.906652020240813	0.961582517431725
GO:0004190	aspartic-type endopeptidase activity	1/1191	36/18639	0.0277777777777778	0.434718723761545	0.907396740510259	0.961582517431725
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/1191	36/18639	0.0277777777777778	0.434718723761545	0.907396740510259	0.961582517431725
GO:0016409	palmitoyltransferase activity	1/1191	36/18639	0.0277777777777778	0.434718723761545	0.907396740510259	0.961582517431725
GO:0017018	myosin phosphatase activity	3/1191	84/18639	0.0357142857142857	0.558924073407701	0.910868764497995	0.963299787677016
GO:0030246	carbohydrate binding	13/1191	280/18639	0.0464285714285714	0.726601295430011	0.913182261090255	0.963299787677016
GO:0019213	deacetylase activity	1/1191	37/18639	0.027027027027027	0.422969569065287	0.913325380087332	0.963299787677016
GO:0030280	structural constituent of skin epidermis	1/1191	37/18639	0.027027027027027	0.422969569065287	0.913325380087332	0.963299787677016
GO:0070001	aspartic-type peptidase activity	1/1191	37/18639	0.027027027027027	0.422969569065287	0.913325380087332	0.963299787677016
GO:0042826	histone deacetylase binding	5/1191	127/18639	0.0393700787401575	0.616136773835261	0.914678124732195	0.963817288831851
GO:0019209	kinase activator activity	6/1191	148/18639	0.0405405405405405	0.63445435359793	0.91730034550933	0.965670231901536
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/1191	38/18639	0.0263157894736842	0.41183879093199	0.918874755010242	0.966417663312748
GO:0008509	monoatomic anion transmembrane transporter activity	6/1191	149/18639	0.0402684563758389	0.630196270687877	0.920274205359201	0.966979851119912
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/1191	39/18639	0.0256410256410256	0.401278821933734	0.924069108366664	0.969214519097771
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	5/1191	130/18639	0.0384615384615385	0.601918232900601	0.924134774023456	0.969214519097771
GO:0004532	RNA exonuclease activity	1/1191	40/18639	0.025	0.39124685138539	0.928931134814799	0.973331779496668
GO:0001727	lipid kinase activity	1/1191	41/18639	0.024390243902439	0.381704245254039	0.93348207940513	0.975357911004613
GO:0008227	G protein-coupled amine receptor activity	1/1191	41/18639	0.024390243902439	0.381704245254039	0.93348207940513	0.975357911004613
GO:0017080	sodium channel regulator activity	1/1191	41/18639	0.024390243902439	0.381704245254039	0.93348207940513	0.975357911004613
GO:0140375	immune receptor activity	6/1191	156/18639	0.0384615384615385	0.601918232900601	0.938588433457372	0.979124674175822
GO:0052689	carboxylic ester hydrolase activity	3/1191	92/18639	0.0326086956521739	0.510321980067901	0.938838685792917	0.979124674175822
GO:0099094	ligand-gated monoatomic cation channel activity	5/1191	136/18639	0.0367647058823529	0.575363016743221	0.940300309364201	0.979735084687024
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/1191	70/18639	0.0285714285714286	0.44713925872616	0.943509144814244	0.982163150747044
GO:0140299	molecular sensor activity	2/1191	71/18639	0.028169014084507	0.440841522687764	0.946504895392607	0.984130620650404
GO:0030295	protein kinase activator activity	5/1191	139/18639	0.0359712230215827	0.562945109907037	0.947159702879996	0.984130620650404
GO:0022836	gated channel activity	14/1191	318/18639	0.0440251572327044	0.688988165961694	0.949175820259717	0.985309718709716
GO:0030594	neurotransmitter receptor activity	3/1191	97/18639	0.0309278350515464	0.48401672336337	0.951938072463889	0.986156748069896
GO:0004521	RNA endonuclease activity	2/1191	73/18639	0.0273972602739726	0.428763672751113	0.952048210781847	0.986156748069896
GO:0048029	monosaccharide binding	2/1191	74/18639	0.027027027027027	0.422969569065287	0.954609771402787	0.986156748069896
GO:0004540	RNA nuclease activity	4/1191	121/18639	0.0330578512396694	0.517351208443491	0.954845100313431	0.986156748069896
GO:0015108	chloride transmembrane transporter activity	4/1191	121/18639	0.0330578512396694	0.517351208443491	0.954845100313431	0.986156748069896
GO:0099095	ligand-gated monoatomic anion channel activity	1/1191	47/18639	0.0212765957446809	0.332976043732247	0.95528422017862	0.986156748069896
GO:0008194	UDP-glycosyltransferase activity	5/1191	145/18639	0.0344827586206897	0.53965082949709	0.958779242407169	0.988851654069386
GO:0016763	pentosyltransferase activity	1/1191	49/18639	0.0204081632653061	0.3193851848044	0.96082983483853	0.988962484779451
GO:0008514	organic anion transmembrane transporter activity	11/1191	269/18639	0.0408921933085502	0.63995767512852	0.960948103735813	0.988962484779451
GO:0015171	amino acid transmembrane transporter activity	3/1191	102/18639	0.0294117647058824	0.460290413394577	0.962379739599298	0.988962484779451
GO:0015605	organophosphate ester transmembrane transporter activity	1/1191	50/18639	0.02	0.312997481108312	0.963339338157912	0.988962484779451
GO:0048020	CCR chemokine receptor binding	1/1191	50/18639	0.02	0.312997481108312	0.963339338157912	0.988962484779451
GO:0005253	monoatomic anion channel activity	3/1191	103/18639	0.029126213592233	0.455821574429581	0.964194193568517	0.988962484779451
GO:0016597	amino acid binding	1/1191	51/18639	0.0196078431372549	0.306860275596385	0.965688192225045	0.989586983416682
GO:0019842	vitamin binding	5/1191	150/18639	0.0333333333333333	0.521662468513854	0.966621553413163	0.989636352303953
GO:0004497	monooxygenase activity	3/1191	106/18639	0.0283018867924528	0.442920963832517	0.969155230393849	0.990325158735707
GO:0003823	antigen binding	6/1191	174/18639	0.0344827586206897	0.53965082949709	0.96966841540951	0.990325158735707
GO:0016758	hexosyltransferase activity	7/1191	197/18639	0.0355329949238579	0.556086895370098	0.971660682224278	0.990325158735707
GO:0005506	iron ion binding	5/1191	154/18639	0.0324675324675325	0.508112794007	0.971878037148445	0.990325158735707
GO:0005254	chloride channel activity	2/1191	83/18639	0.0240963855421687	0.377105398925678	0.972460183770067	0.990325158735707
GO:0005179	hormone activity	4/1191	132/18639	0.0303030303030303	0.474238607739867	0.972609145162618	0.990325158735707
GO:0005261	monoatomic cation channel activity	14/1191	341/18639	0.0410557184750733	0.642516823389497	0.974273775891907	0.99111745354609
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/1191	57/18639	0.0175438596491228	0.27455919395466	0.976939442599154	0.992925724387141
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/1191	60/18639	0.0166666666666667	0.260831234256927	0.981095669718465	0.993476224671261
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1191	60/18639	0.0166666666666667	0.260831234256927	0.981095669718465	0.993476224671261
GO:0015276	ligand-gated monoatomic ion channel activity	6/1191	186/18639	0.032258064516129	0.504834646948891	0.981504887475262	0.993476224671261
GO:0031406	carboxylic acid binding	6/1191	187/18639	0.0320855614973262	0.502134996430448	0.982266035448777	0.993476224671261
GO:0022834	ligand-gated channel activity	6/1191	188/18639	0.0319148936170213	0.499464065598371	0.982997869743214	0.993476224671261
GO:0015179	L-amino acid transmembrane transporter activity	1/1191	62/18639	0.0161290322580645	0.252417323474445	0.98344175559195	0.993476224671261
GO:0043177	organic acid binding	6/1191	189/18639	0.0317460317460317	0.496821398584623	0.983701413873959	0.993476224671261
GO:0008528	G protein-coupled peptide receptor activity	3/1191	122/18639	0.0245901639344262	0.384832968575794	0.986344288507228	0.995246312771734
GO:0008173	RNA methyltransferase activity	1/1191	67/18639	0.0149253731343284	0.233580209782323	0.988111727749164	0.996130668731799
GO:0001653	peptide receptor activity	3/1191	128/18639	0.0234375	0.366793923173804	0.990014439961493	0.997149679168423
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	5/1191	181/18639	0.0276243093922652	0.432316962856785	0.991604450851809	0.997852183665457
GO:0005216	monoatomic ion channel activity	17/1191	448/18639	0.0379464285714286	0.593856827995682	0.994292204911029	0.999535013625596
GO:0015101	organic cation transmembrane transporter activity	1/1191	81/18639	0.0123456790123457	0.193208321671798	0.995301080147317	0.999535013625596
GO:0016757	glycosyltransferase activity	8/1191	267/18639	0.0299625468164794	0.468910084057397	0.995958859730692	0.999535013625596
GO:0051213	dioxygenase activity	1/1191	93/18639	0.010752688172043	0.16827821564963	0.997880586591582	0.999999999999304
GO:0045182	translation regulator activity	11/1191	356/18639	0.0308988764044944	0.48356352418419	0.998349096624946	0.999999999999304
GO:0030371	translation repressor activity	3/1191	329/18639	0.00911854103343465	0.142704018742392	0.999999914311588	0.999999999999304
GO:0004984	olfactory receptor activity	1/1191	419/18639	0.00238663484486874	0.0373505347384621	0.999999999999304	0.999999999999304