category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	23/117	233/9376	7.91049484611716	VIM/COL3A1/FBLN1/COL1A1/COL1A2/COL6A3/COL6A1/COL6A2/ACTG1/COL4A2/VCAN/COL4A1/FBLN2/FN1/PDLIM1/ITGB1/LAMA2/COL5A1/TPM4/MYL9/COL5A2/THBS2/TPM2	12.0071317235552
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	18/117	203/9376	7.10572186434255	COL1A1/COL1A2/COL6A3/COL6A1/COL6A2/ACTG1/COL4A2/PAK3/COL4A1/FN1/JUN/ITGB1/LAMA2/MYL9/CAV1/THBS2/IGF1/FYN	9.88611973546591
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	17/117	238/9376	5.72405372405372	CFD/RPS2/RPL12/RPL5/RPL3/C1R/RPL10A/C1S/RPL13A/JUN/RPL6/NRP1/FOS/RPL4/RPL18A/RPS9/STAT3	8.29801578534237
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	11/117	89/9376	9.90454239892442	COL1A1/COL1A2/COL6A3/COL6A1/COL6A2/COL4A2/COL4A1/FN1/ITGB1/LAMA2/THBS2	9.48779764926699
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	11/117	103/9376	8.55829391751722	COL3A1/COL1A1/COL1A2/COL6A3/COL6A1/COL6A2/COL4A2/COL15A1/COL4A1/COL5A1/COL5A2	8.67019341211807
NA	NA	hsa04518	Integrin signaling	13/117	154/9376	6.76479076479076	COL1A1/COL1A2/COL6A3/COL6A1/COL6A2/ACTG1/COL4A2/COL4A1/FN1/ITGB1/LAMA2/THBS2/IGF1	8.1082639427095
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	10/117	101/9376	7.93433189472793	COL3A1/COL1A1/COL1A2/COL4A2/COL4A1/FOXO1/FN1/JUN/EGR1/STAT3	7.87598497612664
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	18/117	362/9376	3.98470038249044	COL1A1/COL1A2/COL6A3/COL6A1/COL6A2/COL4A2/COL4A1/FN1/INSR/FGF10/ITGB1/HSP90AB1/LAMA2/DDIT4/THBS2/MAGI2/IGF1/GNG4	6.5101767039331
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	11/117	204/9376	4.32109937992291	COL1A1/COL1A2/ACTG1/TIMP3/DDX5/FN1/ITGB1/TWIST2/CAV1/STAT3/IGF1	5.39090227662745
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	11/117	205/9376	4.30002084636231	COL3A1/COL1A1/COL1A2/MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/INSR/MT-ND3/MT-ND1	5.37009284216919
Genetic Information Processing	Translation	hsa03010	Ribosome	11/117	222/9376	3.97073997073997	RPS2/RPL12/RPL5/RPL3/RPL10A/RPL13A/RACK1/RPL6/RPL4/RPL18A/RPS9	5.03537941127504
Organismal Systems	Immune system	hsa04611	Platelet activation	8/117	126/9376	5.08804775471442	COL3A1/COL1A1/COL1A2/ACTG1/PRKG1/ITGB1/GUCY1A2/FYN	5.19310248730321
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	8/117	130/9376	4.93149243918475	COL3A1/COL1A1/COL1A2/COL4A2/COL4A1/JUN/FOS/GNG4	5.0739794436481
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	7/117	99/9376	5.66623499956833	ACTG1/CACNB2/ITGB1/LAMA2/TPM4/TPM2/IGF1	5.24658789427647
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	7/117	103/9376	5.44618703842005	COL3A1/COL1A1/COL1A2/COL4A2/COL4A1/FN1/LAMA2	5.10026495267825
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	7/117	105/9376	5.34245014245014	ACTG1/CACNB2/ITGB1/LAMA2/TPM4/TPM2/IGF1	5.02993909976406
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	6/117	87/9376	5.52667256115532	MT-CO3/MT-CO1/MT-CYB/CACNB2/TPM4/TPM2	4.76815925908562
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	12/117	333/9376	2.88781088781089	COL1A1/COL1A2/COL6A3/COL6A1/COL6A2/COL4A2/COL4A1/FOXO1/FN1/ITGB1/LAMA2/THBS2	3.94294632300783
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	7/117	138/9376	4.06490771708163	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3/MT-ND1	4.07722326734575
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	8/117	184/9376	3.4842066146414	SEMA5A/CXCL12/PAK3/TRPC4/ITGB1/NRP1/MYL9/FYN	3.82549945583692
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	9/117	227/9376	3.17722805828533	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/JUN/FOS/MT-ND3/MT-ND1	3.73272988945645
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	10/117	275/9376	2.91406371406371	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/EGR1/CAV1/MT-ND3/MT-ND1/FYN	3.62138507133662
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	9/117	232/9376	3.10875331564987	TMSB4X/CXCL12/ACTG1/PAK3/FN1/FGF10/ITGB1/GSN/MYL9	3.65593267283686
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	9/117	235/9376	3.06906710310966	MT-CO3/ACTG1/MT-CO1/MT-ND5/PRKG1/MT-CYB/MT-ATP8/MT-ND3/MT-ND1	3.61083945638068
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	5/117	78/9376	5.13697129081744	C1R/C1S/JUN/ITGB1/FOS	4.12412257328879
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	7/117	154/9376	3.64257964257964	ACTG1/EEF2/JUN/CACNB2/MYL9/FOS/GUCY1A2	3.71682756684481
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	5/117	93/9376	4.30842753423399	COL4A2/COL4A1/FN1/ITGB1/LAMA2	3.60425452724574
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	4/117	70/9376	4.57924297924298	ACTG1/LAMA2/CAV1/FYN	3.37874335585736
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/117	109/9376	3.67599780443817	RORA/JUN/HSP90AB1/FOS/STAT3	3.15882776937192
NA	NA	hsa04517	IgSF CAM signaling	9/117	299/9376	2.41214304090558	ACTG1/PAK3/FOXO1/NLGN1/ITGB1/NRP1/MYL9/MAGI2/FYN	2.78958528585997
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	6/117	157/9376	3.06255103707333	MT-CO3/MT-CO1/MT-CYB/JUN/INSR/FOS	2.92960554895805
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	4/117	78/9376	4.10957703265396	ACTG1/FN1/ITGB1/CAV1	3.09991922405015
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	4/117	86/9376	3.72729079705824	ACTG1/CACNB2/ITGB1/LAMA2	2.85607325668117
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	6/117	178/9376	2.7012388360703	SFRP2/APCDD1/MCC/JUN/PRICKLE2/SERPINF1	2.57587695570789
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/117	134/9376	2.99017731853553	PRKG1/RAMP1/CALD1/MYL9/GUCY1A2	2.60830105189971
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	4/117	93/9376	3.44674202738719	ACTG1/INSR/MYL9/FYN	2.66552038331241
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	5/117	138/9376	2.90350551220116	ACTG1/FN1/JUN/ITGB1/FOS	2.53221880731124
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	4/117	95/9376	3.37417903733693	CXCL12/JUN/IL15/FOS	2.61441429467097
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/117	142/9376	2.82171662453353	ACTG1/JUN/HSP90AB1/FOS/CAV1	2.45881914345179
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	4/117	97/9376	3.30460833553617	PRKG1/FOS/GUCY1A2/GNG4	2.56465490259545
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	8/117	308/9376	2.08147408147408	TGM2/MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3/MT-ND1	2.16936308236991
Organismal Systems	Nervous system	hsa04730	Long-term depression	3/117	60/9376	4.00683760683761	PRKG1/GUCY1A2/IGF1	2.62643940549733
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	6/117	200/9376	2.40410256410256	ACTG1/PAK3/JUN/ITGB1/FOS/FYN	2.25623148225411
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	6/117	201/9376	2.39214185482842	ZEB1/PBX1/FOXO1/DDX5/MEIS1/IGF1	2.24271976261723
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	9/117	368/9376	1.95986622073579	MT-CO3/ACTG1/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3/HNRNPA1/MT-ND1	2.11162578256218
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	3/117	62/9376	3.87758478081059	FOXO1/INSR/IGF1	2.5553617094261
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	4/117	106/9376	3.02402838251895	ZEB1/FOXO1/HSP90AB1/IGF1	2.3557336784219
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	5/117	155/9376	2.58505652054039	ACTG1/C1R/ITGB1/CALR/THBS2	2.23675346177376
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	4/117	110/9376	2.91406371406371	INSR/TIMP1/STAT3/IGF1	2.26988111622162
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/117	66/9376	3.64257964257964	RORA/JUN/STAT3	2.42170779303967
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	6/117	212/9376	2.26802128688921	ACTG1/INSR/FGF10/ITGB1/MAGI2/IGF1	2.09917411076274
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	7/117	268/9376	2.09312412297487	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3/MT-ND1	2.04090077901409
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	9/117	388/9376	1.8588421887391	MT-CO3/APOE/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/INSR/MT-ND3/MT-ND1	1.94220124419536
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/117	115/9376	2.78736529171312	EGR1/AKAP13/NACA/FOS	2.167852977903
NA	NA	hsa04081	Hormone signaling	6/117	219/9376	2.19552745580143	PRKG1/RAMP1/INSR/STAT3/IGF1/GNG4	2.01234079590776
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	4/117	116/9376	2.76333628057766	CXCL12/ACTG1/ITGB1/MYL9	2.14810334552924
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	6/117	224/9376	2.14652014652015	JUN/IL15/EGR1/NRP1/CALR/FOS	1.95228951102401
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	4/117	122/9376	2.62743449628696	EEF2/FOXO1/INSR/IGF1	2.03383263682508
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	4/117	122/9376	2.62743449628696	PAK3/JUN/FOS/FYN	2.03383263682508
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	2/117	34/9376	4.71392659627954	RORA/RORB	2.43864941605198
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/117	78/9376	3.08218277449047	JUN/ITGB1/FOS	2.07571587481151
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	2/117	38/9376	4.21772379667116	INSR/IGF1	2.23413880985673
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/117	133/9376	2.41012788381209	FOXO1/INSR/STAT3/IGF1	1.84108725412352
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/117	248/9376	1.93879239040529	ACTG1/PAK3/JUN/HSP90AB1/MYL9/FOS	1.68424052333765
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/117	136/9376	2.35696329813977	JUN/RACK1/FOS/STAT3	1.79183533666382
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/117	88/9376	2.73193473193473	CFD/C1R/C1S	1.83488259573561
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/117	90/9376	2.67122507122507	FOXO1/INSR/IGF1	1.79076412018106
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/117	90/9376	2.67122507122507	JUN/FOS/STAT3	1.79076412018106
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/117	91/9376	2.64187094956326	CD81/JUN/FOS	1.76915257093799
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/117	94/9376	2.55755591925805	JUN/HSP90AB1/FOS	1.70601686220357
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	4/117	148/9376	2.16585816585817	JUN/FGF10/FOS/IGF1	1.60701270655472
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/117	149/9376	2.15132220501348	MT-ND5/MT-ND3/MT-ND1/GNG4	1.59241508017881
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	2/117	48/9376	3.33903133903134	BCAT1/PCCA	1.82624448593273
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	3/117	98/9376	2.45316588173731	MARCKS/PLPP1/GSN	1.62553967337718
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/117	99/9376	2.42838642838643	JUN/FOS/IGF1	1.60603890378738
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/117	99/9376	2.42838642838643	CFD/C1R/C1S	1.60603890378738
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/117	99/9376	2.42838642838643	JUN/PLPP1/FOS	1.60603890378738
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/117	50/9376	3.20547008547009	CXCL12/IL15	1.75766050888591
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/117	50/9376	3.20547008547009	CD81/THBS2	1.75766050888591
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	5/117	214/9376	1.87235402188673	PAK3/JUN/CALR/FOS/GNG4	1.45111234790487
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	5/117	217/9376	1.84646894324314	JUN/FGF10/HSP90AB1/FOS/STAT3	1.41812134209014
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/117	52/9376	3.08218277449047	INSR/IGF1	1.69245026709566
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/117	103/9376	2.33408015932288	JUN/CALR/FOS	1.53033649323843
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	4/117	166/9376	1.93100607558439	PRKG1/INSR/MYL9/GUCY1A2	1.36042082399245
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/117	227/9376	1.7651266990474	CXCL12/AKAP13/CALR/STAT3/GNG4	1.31176487822991
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	3/117	109/9376	2.2055986826629	FOXO1/INSR/STAT3	1.4231247092945
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	4/117	170/9376	1.88557063851181	ACTG1/JUN/ITGB1/MYL9	1.30981123504927
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/117	112/9376	2.14652014652015	ITGB1/LAMA2/STAT3	1.37210692328489
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/117	59/9376	2.71650007243228	PRKG1/INSR	1.48671701284834
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	6/117	300/9376	1.60273504273504	JUN/CACNB2/INSR/FGF10/FOS/IGF1	1.19271409791876
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/117	174/9376	1.84222418705177	DNAJA1/HSP90AB1/PDIA6/CALR	1.26054323516579
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/117	115/9376	2.09052396878484	FOS/GNG4/FYN	1.32267066176435
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	5/117	238/9376	1.68354521295698	PAK3/INSR/FGF10/IGF1/GNG4	1.20067833653784
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/117	119/9376	2.02025425554837	JUN/IL15/FOS	1.25905090861002
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/117	65/9376	2.46574621959237	PBX1/PDE8B	1.3329498949345
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/117	122/9376	1.97057587221522	FOS/STAT3/IGF1	1.21294521526365
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/117	253/9376	1.58373027938245	ACTG1/FOXO1/JUN/ITGB1/MYL9	1.0580353347609
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/117	69/9376	2.32280440976093	JUN/FOS	1.23968643616257
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	6/117	323/9376	1.48860839882512	VIM/ZEB1/TIMP3/MARCKS/DDIT4/STAT3	1.00452894655231
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/117	70/9376	2.28962148962149	PAK3/JUN	1.21738034128967
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/117	71/9376	2.25737329962682	FOS/STAT3	1.19545090877119
Cellular Processes	Cell motility	hsa04814	Motor proteins	4/117	194/9376	1.65230416776809	ACTG1/TPM4/MYL9/TPM2	1.03199810814329
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/117	196/9376	1.63544392115821	JUN/FOS/STAT3/GNG4	1.01060269388589
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/117	73/9376	2.19552745580143	FGF10/IGF1	1.15267268279605
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/117	21/9376	3.81603581603582	BCAT1	1.45218669226776
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/117	137/9376	1.75481938985589	ACTG1/JUN/FOS	1.00043153967491
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/117	139/9376	1.72957019000184	JUN/HSP90AB1/FOS	0.974104469190642
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/117	205/9376	1.56364394413175	VIM/JUN/CALR/STAT3	0.917212481627336
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/117	78/9376	2.05478851632698	PABPC1/BTG1	1.05151252557287
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/117	142/9376	1.69302997472012	JUN/FOS/FYN	0.935400899283154
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	2/117	80/9376	2.0034188034188	STAT3/IGF1	1.01315454768828
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	3/117	144/9376	1.66951566951567	MEIS1/STAT3/IGF1	0.910103157220045
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/117	82/9376	1.95455493016469	HSP90AB1/CALR	0.975894890585068
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/117	216/9376	1.48401392845837	JUN/HSP90AB1/FOS/STAT3	0.808972065431395
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/117	149/9376	1.61349165376011	PLPP1/INSR/FYN	0.848531676673428
NA	NA	hsa04382	Cornified envelope formation	4/117	217/9376	1.47717515459451	S100A6/S100A4/COL4A2/COL4A1	0.799429531404869
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/117	86/9376	1.86364539852912	PAK3/JUN	0.904426667172924
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/117	87/9376	1.84222418705177	JUN/FOS	0.88715474809864
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	3/117	154/9376	1.56110556110556	CACNB2/TPM4/TPM2	0.789203316268346
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/117	89/9376	1.80082589071353	PRKG1/GUCY1A2	0.853280681138848
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/117	89/9376	1.80082589071353	PLCL1/GNG4	0.853280681138848
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	1/117	29/9376	2.76333628057766	RASSF4	1.06904145829047
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/117	91/9376	1.76124729970884	PDE8B/GNG4	0.820260945452345
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/117	158/9376	1.52158390133074	INSR/DDIT4/IGF1	0.74324311880944
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/117	160/9376	1.5025641025641	VCAN/NLGN1/ITGB1	0.720736887019878
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/117	31/9376	2.58505652054039	PCCA	0.993647797319001
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/117	93/9376	1.72337101369359	JUN/FOS	0.788052095445741
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/117	93/9376	1.72337101369359	JUN/EGR1	0.788052095445741
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/117	93/9376	1.72337101369359	PRKG1/GUCY1A2	0.788052095445741
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/117	32/9376	2.5042735042735	PCCA	0.95814647762483
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/117	163/9376	1.47490954852918	JUN/FOS/STAT3	0.687544314690906
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/117	33/9376	2.42838642838643	BCAT1	0.923966100627801
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/117	36/9376	2.22602089268756	GALNT13	0.828461270219553
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	7/117	480/9376	1.16866096866097	MT-CO3/MT-CO1/MT-ND5/MT-CYB/MT-ATP8/MT-ND3/MT-ND1	0.426416841364957
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/117	109/9376	1.47039912177527	JUN/FOS	0.555273179255785
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/117	110/9376	1.45703185703186	HSP90AB1/IGF1	0.541992397727352
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/117	43/9376	1.86364539852912	PLPP1	0.638051281632156
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/117	193/9376	1.24564899694433	CXCL12/STAT3/GNG4	0.387612598583814
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/117	47/9376	1.70503727950536	INSR	0.544678196489936
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/117	122/9376	1.31371724814348	ACTG1/FOXO1	0.392057793702226
NA	NA	hsa03272	Virion - Hepatitis viruses	1/117	48/9376	1.66951566951567	CD81	0.522737459432633
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/117	49/9376	1.63544392115821	GALNT13	0.50130358235218
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/117	49/9376	1.63544392115821	JUN	0.50130358235218
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/117	205/9376	1.17273295809881	JUN/GSN/STAT3	0.281086715835643
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/117	51/9376	1.57130886542651	PLPP1	0.459862671777999
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/117	51/9376	1.57130886542651	ACTG1	0.459862671777999
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/117	128/9376	1.25213675213675	PDE8B/GUCY1A2	0.322859638041425
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/117	52/9376	1.54109138724523	APOE	0.439812620719838
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/117	54/9376	1.48401392845837	BCAT1	0.400956000368313
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/117	54/9376	1.48401392845837	REV3L	0.400956000368313
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/117	133/9376	1.20506394190605	FOS/GNG4	0.26773501471577
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/117	55/9376	1.45703185703186	PLPP1	0.382114124294424
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/117	138/9376	1.16140220488047	FOXO1/INSR	0.214712117259488
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/117	140/9376	1.14481074481074	EGR1/GNG4	0.194052557118368
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/117	143/9376	1.12079373617835	C1R/C1S	0.163620434752063
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/117	226/9376	1.06376219650556	JUN/MYL9/FOS	0.109069536849273
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/117	63/9376	1.27201193867861	PTGDS	0.243506167821097
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/117	65/9376	1.23287310979619	PLPP1	0.211774850984929
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/117	65/9376	1.23287310979619	TRPC4	0.211774850984929
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/117	68/9376	1.17848164906988	STAT3	0.166041392149929
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/117	155/9376	1.03402260821616	PBX1/PDE8B	0.0480110240359857
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/117	69/9376	1.16140220488047	FYN	0.151260551205153
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/117	69/9376	1.16140220488047	GUCY1A2	0.151260551205153
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/117	156/9376	1.02739425816349	CD81/STAT3	0.0387840278412516
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/117	70/9376	1.14481074481074	STAT3	0.136698834005827
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/117	157/9376	1.02085034569111	PBX1/CALR	0.0296154070063856
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/117	71/9376	1.12868664981341	JUN	0.122349164334744
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/117	73/9376	1.09776372790071	MAP1B	0.0942592978292726
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/117	73/9376	1.09776372790071	STAT3	0.0942592978292726
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/117	75/9376	1.06849002849003	BCAT1	0.066940612747545
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/117	75/9376	1.06849002849003	REV3L	0.066940612747545
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/117	75/9376	1.06849002849003	IGF1	0.066940612747545
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/117	76/9376	1.05443094916779	PLIN2	0.0535559535855093
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/117	76/9376	1.05443094916779	ACTG1	0.0535559535855093
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/117	76/9376	1.05443094916779	IGF1	0.0535559535855093
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/117	77/9376	1.04073704073704	STAT3	0.0403471853205572
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/117	168/9376	0.954008954008954	HSP90AB1/STAT3	-0.067614804954192
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/117	168/9376	0.954008954008954	IL15/STAT3	-0.067614804954192
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/117	78/9376	1.02739425816349	INPP4B	0.0273091763342215
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/117	83/9376	0.965503037792194	AUTS2	-0.0354844809984004
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/117	187/9376	0.857077562959916	JUN/HSP90AB1	-0.221913446020714
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/117	98/9376	0.817721960579103	INPP4B	-0.203899766976252
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/117	99/9376	0.809462142795476	IGF1	-0.214235591457163
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/117	100/9376	0.801367521367521	CXCL12	-0.224474193050126
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/117	103/9376	0.778026719774292	PABPC1	-0.254627736481483
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/117	104/9376	0.770545693622617	PLPP1	-0.264498186139801
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/117	105/9376	0.763207163207163	CXCL12	-0.274281456149618
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/117	105/9376	0.763207163207163	JUN	-0.274281456149618
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/117	105/9376	0.763207163207163	JUN	-0.274281456149618
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/117	107/9376	0.748941608754693	FOXO1	-0.293593689331618
NA	NA	hsa04519	Cadherin signaling	4/117	404/9376	0.793433189472793	VIM/ACTG1/PRICKLE2/LHFPL6	-0.477093083993597
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/117	110/9376	0.728515928515929	THSD4	-0.321951961519783
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/117	115/9376	0.696841322928279	GNG4	-0.367693970512967
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/117	116/9376	0.690834070144415	PCCA	-0.37662717858268
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/117	116/9376	0.690834070144415	GNG4	-0.37662717858268
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/117	117/9376	0.684929505442326	ACTG1	-0.385491805436535
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/117	120/9376	0.667806267806268	JUN	-0.411686770317561
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/117	125/9376	0.641094017094017	FYN	-0.454085768679113
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/117	243/9376	0.659561745981499	DDX5/HNRNPA1	-0.604409510618843
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/117	133/9376	0.602531970953024	FYN	-0.518941104988104
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/117	138/9376	0.580701102440233	IGF1	-0.557790112757764
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/117	144/9376	0.55650522317189	FOXO1	-0.602862658754271
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/117	144/9376	0.55650522317189	RORA	-0.602862658754271
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/117	150/9376	0.534245014245014	FGF10	-0.646387492015262
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/117	154/9376	0.52036852036852	BCAT1	-0.674608809019886
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/117	157/9376	0.510425172845555	FOXO1	-0.69538212848153
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/117	157/9376	0.510425172845555	ACTG1	-0.69538212848153
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/117	169/9376	0.474181965306226	DDIT4	-0.775383018471742
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/117	170/9376	0.471392659627954	ACTG1	-0.78184145141978
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/117	173/9376	0.463218220443654	ACTG1	-0.801037104567015
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/117	298/9376	0.53783055125337	CXCL12/IL15	-0.911403733580526
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/117	180/9376	0.445204178537512	CALR	-0.844824460648992
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/117	191/9376	0.419564147312838	GNG4	-0.911019893734529
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/117	195/9376	0.410957703265396	ACTG1	-0.934362327524862
NA	NA	hsa04082	Neuroactive ligand signaling	1/117	199/9376	0.402697246918352	GNG4	-0.95734222794467
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/117	250/9376	0.320547008547009	CAV1	-1.22401210887498
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/117	254/9376	0.315499024160441	FGF10	-1.24320406925587
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/117	449/9376	0.178478289836864	PRKG1	-2.00533057300982