ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0043021 ribonucleoprotein complex binding 43/1698 177/18639 0.242937853107345 2.66673653949811 1.65502328345563e-09 1.91486193895817e-06 GO:0140098 catalytic activity, acting on RNA 65/1698 387/18639 0.167958656330749 1.843687511984 9.48913123242258e-07 0.000548946241795646 GO:0043022 ribosome binding 27/1698 112/18639 0.241071428571429 2.64624873801111 2.01701402148053e-06 0.000777895074284326 GO:0003735 structural constituent of ribosome 35/1698 175/18639 0.2 2.19540636042403 6.93671033769119e-06 0.00200644346517718 GO:0035091 phosphatidylinositol binding 48/1698 284/18639 0.169014084507042 1.85527298064002 2.04224973726041e-05 0.00472576589202058 GO:0005049 nuclear export signal receptor activity 7/1698 12/18639 0.583333333333333 6.40326855123675 2.69941042527479e-05 0.00520536310340489 GO:0003712 transcription coregulator activity 72/1698 495/18639 0.145454545454545 1.59665917121748 4.59989855920679e-05 0.00760297519000322 GO:0001098 basal transcription machinery binding 16/1698 60/18639 0.266666666666667 2.92720848056537 6.51397894294617e-05 0.00772894719983533 GO:0001099 basal RNA polymerase II transcription machinery binding 16/1698 60/18639 0.266666666666667 2.92720848056537 6.51397894294617e-05 0.00772894719983533 GO:0140142 nucleocytoplasmic carrier activity 11/1698 32/18639 0.34375 3.7733546819788 7.36824268152821e-05 0.00772894719983533 GO:0051020 GTPase binding 50/1698 315/18639 0.158730158730159 1.74238600033653 7.47956391250511e-05 0.00772894719983533 GO:0031267 small GTPase binding 46/1698 283/18639 0.162544169611307 1.78425251907253 8.01619415713258e-05 0.00772894719983533 GO:0043024 ribosomal small subunit binding 8/1698 20/18639 0.4 4.39081272084806 0.000216032343363792 0.0192268785593775 GO:0052742 phosphatidylinositol kinase activity 9/1698 26/18639 0.346153846153846 3.79974177765697 0.000315072587720372 0.026038498856605 GO:0008135 translation factor activity, RNA binding 18/1698 83/18639 0.216867469879518 2.3805611137128 0.000406653432703584 0.0313555305578148 GO:0000287 magnesium ion binding 37/1698 230/18639 0.160869565217391 1.76587033338454 0.000468875049833044 0.0313555305578148 GO:0180051 translation factor activity 18/1698 84/18639 0.214285714285714 2.35222110045432 0.000474189723912967 0.0313555305578148 GO:0042393 histone binding 39/1698 247/18639 0.157894736842105 1.73321554770318 0.000489647372947881 0.0313555305578148 GO:0000149 SNARE binding 21/1698 106/18639 0.19811320754717 2.17469497966531 0.0005149136392381 0.0313555305578148 GO:0004535 poly(A)-specific ribonuclease activity 6/1698 13/18639 0.461538461538462 5.0663223702093 0.000553519213298287 0.0320210864893059 GO:0045296 cadherin binding 49/1698 334/18639 0.146706586826347 1.61040286917331 0.00058425998285009 0.0321899428646454 GO:0001091 RNA polymerase II general transcription initiation factor binding 8/1698 24/18639 0.333333333333333 3.65901060070671 0.00090603363772737 0.0462374205011409 GO:0019887 protein kinase regulator activity 39/1698 255/18639 0.152941176470588 1.67884015797132 0.000919153562252585 0.0462374205011409 GO:0106310 protein serine kinase activity 51/1698 361/18639 0.141274238227147 1.55077180583969 0.00108764403465929 0.0524335061708667 GO:0070273 phosphatidylinositol-4-phosphate binding 9/1698 31/18639 0.290322580645161 3.18688020061553 0.00133914982978169 0.0611533294092697 GO:0000339 RNA cap binding 7/1698 20/18639 0.35 3.84196113074205 0.00137423212155662 0.0611533294092697 GO:0019207 kinase regulator activity 42/1698 287/18639 0.146341463414634 1.60639489787124 0.00145580136626617 0.0623837844729613 GO:0140104 molecular carrier activity 37/1698 249/18639 0.14859437751004 1.63112520754396 0.0020614393949524 0.0851816207128546 GO:0140296 general transcription initiation factor binding 12/1698 53/18639 0.226415094339623 2.48536569104607 0.00245679193837188 0.096801187830893 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 13/1698 60/18639 0.216666666666667 2.37835689045936 0.00250997029812169 0.096801187830893 GO:0046966 nuclear thyroid hormone receptor binding 8/1698 28/18639 0.285714285714286 3.13629480060575 0.00275547061634046 0.102841274293739 GO:0005525 GTP binding 51/1698 378/18639 0.134920634920635 1.48102810028605 0.00292522928123092 0.105765321199506 GO:0008168 methyltransferase activity 31/1698 204/18639 0.151960784313725 1.66807836208688 0.00321985237333769 0.1128899756349 GO:0032266 phosphatidylinositol-3-phosphate binding 11/1698 48/18639 0.229166666666667 2.51556978798587 0.00332007669642226 0.112980256992957 GO:0035198 miRNA binding 10/1698 42/18639 0.238095238095238 2.61357900050479 0.00374328549360978 0.123742323317329 GO:0016741 transferase activity, transferring one-carbon groups 32/1698 215/18639 0.148837209302326 1.63379077985044 0.00386786326539006 0.124308827723786 GO:0005484 SNAP receptor activity 9/1698 36/18639 0.25 2.74425795053004 0.00412988748173095 0.129142697739533 GO:0005543 phospholipid binding 63/1698 497/18639 0.126760563380282 1.39145473548002 0.0045261776833687 0.137810199464673 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 26/1698 167/18639 0.155688622754491 1.70899896320433 0.00477480880615744 0.141652661249338 GO:1901981 phosphatidylinositol phosphate binding 28/1698 185/18639 0.151351351351351 1.66138859707764 0.00522480103890647 0.146314532708134 GO:0000049 tRNA binding 15/1698 80/18639 0.1875 2.05819346289753 0.00530877167727991 0.146314532708134 GO:0003743 translation initiation factor activity 11/1698 51/18639 0.215686274509804 2.36759509457493 0.00543779162182347 0.146314532708134 GO:0005048 signal sequence binding 11/1698 51/18639 0.215686274509804 2.36759509457493 0.00543779162182347 0.146314532708134 GO:0003714 transcription corepressor activity 30/1698 204/18639 0.147058823529412 1.61426938266473 0.00599609684189343 0.149934320016549 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 9/1698 38/18639 0.236842105263158 2.59982332155477 0.00606201850229859 0.149934320016549 GO:0061665 SUMO ligase activity 5/1698 14/18639 0.357142857142857 3.92036850075719 0.00619481418831441 0.149934320016549 GO:0070063 RNA polymerase binding 12/1698 59/18639 0.203389830508475 2.23261663771935 0.00620324213165772 0.149934320016549 GO:0016922 nuclear receptor binding 22/1698 137/18639 0.160583941605839 1.7627350339171 0.00622026565323627 0.149934320016549 GO:0031491 nucleosome binding 14/1698 74/18639 0.189189189189189 2.07673574634705 0.00640131453721588 0.151149406521608 GO:0030515 snoRNA binding 8/1698 32/18639 0.25 2.74425795053004 0.00672370066880861 0.154113618155894 GO:0008173 RNA methyltransferase activity 13/1698 67/18639 0.194029850746269 2.12987184220242 0.00679325369572221 0.154113618155894 GO:0140101 catalytic activity, acting on a tRNA 22/1698 139/18639 0.158273381294964 1.73737193990391 0.00738170308571592 0.164242893657179 GO:0030145 manganese ion binding 13/1698 68/18639 0.191176470588235 2.09855019746414 0.00771596221109296 0.168440910910086 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 12/1698 61/18639 0.19672131147541 2.15941609222036 0.00815455484850709 0.171542181085867 GO:0019905 syntaxin binding 12/1698 61/18639 0.19672131147541 2.15941609222036 0.00815455484850709 0.171542181085867 GO:0051287 NAD binding 11/1698 54/18639 0.203703703703704 2.23606203376521 0.00849930924692235 0.173823256938047 GO:0004532 RNA exonuclease activity 9/1698 40/18639 0.225 2.46983215547703 0.00862387093863786 0.173823256938047 GO:0019001 guanyl nucleotide binding 51/1698 400/18639 0.1275 1.39957155477032 0.00887828132010744 0.173823256938047 GO:0032561 guanyl ribonucleotide binding 51/1698 400/18639 0.1275 1.39957155477032 0.00887828132010744 0.173823256938047 GO:0001094 TFIID-class transcription factor complex binding 4/1698 10/18639 0.4 4.39081272084806 0.00920074492201 0.173823256938047 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 4/1698 10/18639 0.4 4.39081272084806 0.00920074492201 0.173823256938047 GO:0003713 transcription coactivator activity 35/1698 256/18639 0.13671875 1.50076606669611 0.00998978888873746 0.173823256938047 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 10/1698 48/18639 0.208333333333333 2.2868816254417 0.0100986664987587 0.173823256938047 GO:0001727 lipid kinase activity 9/1698 41/18639 0.219512195121951 2.40959234680686 0.0101772885986289 0.173823256938047 GO:0061650 ubiquitin-like protein conjugating enzyme activity 9/1698 41/18639 0.219512195121951 2.40959234680686 0.0101772885986289 0.173823256938047 GO:0015631 tubulin binding 49/1698 385/18639 0.127272727272727 1.39707677481529 0.0104912391589533 0.173823256938047 GO:0019789 SUMO transferase activity 7/1698 28/18639 0.25 2.74425795053004 0.0110132868706743 0.173823256938047 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 45/1698 349/18639 0.128939828080229 1.41537659339658 0.0110481898955682 0.173823256938047 GO:0000175 3'-5'-RNA exonuclease activity 8/1698 35/18639 0.228571428571429 2.5090358404846 0.0117881634344419 0.173823256938047 GO:0042056 chemoattractant activity 9/1698 42/18639 0.214285714285714 2.35222110045432 0.0119320167181795 0.173823256938047 GO:0043175 RNA polymerase core enzyme binding 9/1698 42/18639 0.214285714285714 2.35222110045432 0.0119320167181795 0.173823256938047 GO:0032182 ubiquitin-like protein binding 19/1698 120/18639 0.158333333333333 1.73803003533569 0.0121387663750527 0.173823256938047 GO:0004197 cysteine-type endopeptidase activity 15/1698 88/18639 0.170454545454545 1.87108496627048 0.0128078150923726 0.173823256938047 GO:0004540 RNA nuclease activity 19/1698 121/18639 0.15702479338843 1.72366615074614 0.013207590491027 0.173823256938047 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 33/1698 243/18639 0.135802469135802 1.49070802251014 0.0132835493455066 0.173823256938047 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/1698 29/18639 0.241379310344828 2.649628366029 0.0134020397518231 0.173823256938047 GO:0097472 cyclin-dependent protein kinase activity 7/1698 29/18639 0.241379310344828 2.649628366029 0.0134020397518231 0.173823256938047 GO:0048407 platelet-derived growth factor binding 4/1698 11/18639 0.363636363636364 3.99164792804369 0.0134280565999673 0.173823256938047 GO:0180030 inositol phosphate kinase activity 4/1698 11/18639 0.363636363636364 3.99164792804369 0.0134280565999673 0.173823256938047 GO:0019843 rRNA binding 12/1698 65/18639 0.184615384615385 2.02652894808372 0.0134683769324995 0.173823256938047 GO:0000993 RNA polymerase II complex binding 8/1698 36/18639 0.222222222222222 2.43934040047114 0.0139762422780736 0.173823256938047 GO:0008408 3'-5' exonuclease activity 11/1698 58/18639 0.189655172413793 2.08185085902279 0.014476396643279 0.173823256938047 GO:0004676 3-phosphoinositide-dependent protein kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0004711 ribosomal protein S6 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0035175 histone H3S10 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0035979 histone H2AXS139 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0044022 histone H3S28 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0044023 histone H4S1 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0044024 histone H2AS1 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0044025 histone H2BS14 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0072354 histone H3T3 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0072371 histone H2AS121 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0072518 Rho-dependent protein serine/threonine kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0140823 histone H2BS36 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0140855 histone H3S57 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0140995 histone H2A kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0140997 histone H4 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0140998 histone H2B kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:1990244 histone H2AT120 kinase activity 33/1698 245/18639 0.13469387755102 1.47853897742843 0.0148733815357534 0.173823256938047 GO:0004677 DNA-dependent protein kinase activity 33/1698 246/18639 0.134146341463415 1.47252865638197 0.0157239577372377 0.180124941603803 GO:0140857 histone H3T45 kinase activity 33/1698 246/18639 0.134146341463415 1.47252865638197 0.0157239577372377 0.180124941603803 GO:0035402 histone H3T11 kinase activity 33/1698 247/18639 0.133603238866397 1.46656700190269 0.0166132121111878 0.186616372938295 GO:0035403 histone H3T6 kinase activity 33/1698 247/18639 0.133603238866397 1.46656700190269 0.0166132121111878 0.186616372938295 GO:0004679 AMP-activated protein kinase activity 33/1698 248/18639 0.133064516129032 1.46065342528212 0.0175423359477716 0.195158487418959 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 11/1698 60/18639 0.183333333333333 2.01245583038869 0.0184479084110423 0.195391171495239 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 11/1698 60/18639 0.183333333333333 2.01245583038869 0.0184479084110423 0.195391171495239 GO:0000340 RNA 7-methylguanosine cap binding 4/1698 12/18639 0.333333333333333 3.65901060070671 0.0187120259975129 0.195391171495239 GO:0003995 acyl-CoA dehydrogenase activity 4/1698 12/18639 0.333333333333333 3.65901060070671 0.0187120259975129 0.195391171495239 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 4/1698 12/18639 0.333333333333333 3.65901060070671 0.0187120259975129 0.195391171495239 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1698 12/18639 0.333333333333333 3.65901060070671 0.0187120259975129 0.195391171495239 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/1698 68/18639 0.176470588235294 1.93712325919767 0.018937558204965 0.195391171495239 GO:0004527 exonuclease activity 14/1698 84/18639 0.166666666666667 1.82950530035336 0.0190520984843493 0.195391171495239 GO:0042162 telomeric DNA binding 8/1698 38/18639 0.210526315789474 2.31095406360424 0.0192147072106743 0.195391171495239 GO:0008327 methyl-CpG binding 7/1698 31/18639 0.225806451612903 2.47868460047874 0.0192520255405853 0.195391171495239 GO:0140297 DNA-binding transcription factor binding 58/1698 488/18639 0.118852459016393 1.30464722238313 0.0217140554647508 0.216965322711184 GO:0016853 isomerase activity 25/1698 180/18639 0.138888888888889 1.52458775029446 0.022100417135482 0.216965322711184 GO:0019211 phosphatase activator activity 6/1698 25/18639 0.24 2.63448763250883 0.0221278375798787 0.216965322711184 GO:0042974 nuclear retinoic acid receptor binding 6/1698 25/18639 0.24 2.63448763250883 0.0221278375798787 0.216965322711184 GO:0022884 macromolecule transmembrane transporter activity 7/1698 32/18639 0.21875 2.40122570671378 0.0227599565046828 0.221287980469899 GO:0004518 nuclease activity 28/1698 209/18639 0.133971291866029 1.47060713138452 0.0249309008170635 0.240164482462337 GO:0005172 vascular endothelial growth factor receptor binding 4/1698 13/18639 0.307692307692308 3.3775482468062 0.0251165966965798 0.240164482462337 GO:0004177 aminopeptidase activity 8/1698 40/18639 0.2 2.19540636042403 0.0257197378369649 0.243915874404659 GO:0050681 nuclear androgen receptor binding 6/1698 26/18639 0.230769230769231 2.53316118510465 0.0266113842399717 0.248301383593929 GO:0070412 R-SMAD binding 6/1698 26/18639 0.230769230769231 2.53316118510465 0.0266113842399717 0.248301383593929 GO:0030295 protein kinase activator activity 20/1698 139/18639 0.143884892086331 1.57942903627628 0.027052104207134 0.250394276541232 GO:0031418 L-ascorbic acid binding 5/1698 20/18639 0.25 2.74425795053004 0.0303388102748572 0.278587329269919 GO:0008175 tRNA methyltransferase activity 7/1698 34/18639 0.205882352941176 2.25997713573062 0.0310463627517332 0.280630013310588 GO:0016831 carboxy-lyase activity 7/1698 34/18639 0.205882352941176 2.25997713573062 0.0310463627517332 0.280630013310588 GO:0005385 zinc ion transmembrane transporter activity 6/1698 27/18639 0.222222222222222 2.43934040047114 0.0316578275065091 0.281754664807931 GO:0008320 protein transmembrane transporter activity 6/1698 27/18639 0.222222222222222 2.43934040047114 0.0316578275065091 0.281754664807931 GO:0042043 neurexin family protein binding 4/1698 14/18639 0.285714285714286 3.13629480060575 0.0326853096998859 0.28867865131884 GO:0016859 cis-trans isomerase activity 8/1698 42/18639 0.19047619047619 2.09086320040384 0.0336183308132931 0.288714122056555 GO:0031492 nucleosomal DNA binding 8/1698 42/18639 0.19047619047619 2.09086320040384 0.0336183308132931 0.288714122056555 GO:0048487 beta-tubulin binding 8/1698 42/18639 0.19047619047619 2.09086320040384 0.0336183308132931 0.288714122056555 GO:0009055 electron transfer activity 17/1698 116/18639 0.146551724137931 1.60870293651761 0.0336874731872385 0.288714122056555 GO:0004674 protein serine/threonine kinase activity 51/1698 433/18639 0.117782909930716 1.29290674805572 0.0343633285598207 0.292340964292004 GO:0061980 regulatory RNA binding 10/1698 58/18639 0.172413793103448 1.89259169002071 0.035346241674193 0.298496948606344 GO:0043015 gamma-tubulin binding 7/1698 35/18639 0.2 2.19540636042403 0.035860912581056 0.298496948606344 GO:0061631 ubiquitin conjugating enzyme activity 7/1698 35/18639 0.2 2.19540636042403 0.035860912581056 0.298496948606344 GO:0010314 phosphatidylinositol-5-phosphate binding 5/1698 21/18639 0.238095238095238 2.61357900050479 0.0369212941987859 0.303183432469951 GO:0043130 ubiquitin binding 15/1698 100/18639 0.15 1.64655477031802 0.0369480241817313 0.303183432469951 GO:0004860 protein kinase inhibitor activity 13/1698 84/18639 0.154761904761905 1.69882635032812 0.0400587682938453 0.326180142370129 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 7/1698 36/18639 0.194444444444444 2.13442285041225 0.0411434192059138 0.326180142370129 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 7/1698 36/18639 0.194444444444444 2.13442285041225 0.0411434192059138 0.326180142370129 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 7/1698 36/18639 0.194444444444444 2.13442285041225 0.0411434192059138 0.326180142370129 GO:0004559 alpha-mannosidase activity 4/1698 15/18639 0.266666666666667 2.92720848056537 0.041442075132592 0.326180142370129 GO:0042809 nuclear vitamin D receptor binding 4/1698 15/18639 0.266666666666667 2.92720848056537 0.041442075132592 0.326180142370129 GO:0004386 helicase activity 21/1698 155/18639 0.135483870967742 1.48721076028725 0.0425608769093247 0.331860847959657 GO:0008094 ATP-dependent activity, acting on DNA 27/1698 210/18639 0.128571428571429 1.41133266027259 0.0427374817164986 0.331860847959657 GO:0008017 microtubule binding 34/1698 276/18639 0.123188405797101 1.35224304808726 0.0434972107748426 0.335508485776619 GO:0070034 telomerase RNA binding 5/1698 22/18639 0.227272727272727 2.4947799550273 0.0443131899248144 0.339538812867618 GO:0003724 RNA helicase activity 12/1698 77/18639 0.155844155844156 1.71070625487587 0.0451820182118041 0.343918388625377 GO:0016836 hydro-lyase activity 10/1698 61/18639 0.163934426229508 1.79951341018363 0.0478157447966094 0.360560676714726 GO:0019209 kinase activator activity 20/1698 148/18639 0.135135135135135 1.48338267596218 0.0479916544633257 0.360560676714726 GO:0140097 catalytic activity, acting on DNA 40/1698 336/18639 0.119047619047619 1.3067895002524 0.0484611836600659 0.360641285425005 GO:0008276 protein methyltransferase activity 14/1698 95/18639 0.147368421052632 1.61766784452297 0.0486257912932591 0.360641285425005 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 4/1698 16/18639 0.25 2.74425795053004 0.0513924106389089 0.369323100057252 GO:0005521 lamin binding 4/1698 16/18639 0.25 2.74425795053004 0.0513924106389089 0.369323100057252 GO:0008142 oxysterol binding 4/1698 16/18639 0.25 2.74425795053004 0.0513924106389089 0.369323100057252 GO:0015923 mannosidase activity 4/1698 16/18639 0.25 2.74425795053004 0.0513924106389089 0.369323100057252 GO:0043023 ribosomal large subunit binding 4/1698 16/18639 0.25 2.74425795053004 0.0513924106389089 0.369323100057252 GO:0008171 O-methyltransferase activity 5/1698 23/18639 0.217391304347826 2.38631126133047 0.0525261426976109 0.372254848972449 GO:0140102 catalytic activity, acting on a rRNA 5/1698 23/18639 0.217391304347826 2.38631126133047 0.0525261426976109 0.372254848972449 GO:0008186 ATP-dependent activity, acting on RNA 12/1698 79/18639 0.151898734177215 1.66739723576508 0.0533624707907915 0.372254848972449 GO:0046332 SMAD binding 12/1698 79/18639 0.151898734177215 1.66739723576508 0.0533624707907915 0.372254848972449 GO:0140463 chromatin-protein adaptor activity 9/1698 54/18639 0.166666666666667 1.82950530035336 0.053651679799732 0.372254848972449 GO:0030291 protein serine/threonine kinase inhibitor activity 8/1698 46/18639 0.173913043478261 1.90904900906437 0.0540041675279904 0.372254848972449 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 3/1698 10/18639 0.3 3.29310954063604 0.0556612695524923 0.372254848972449 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/1698 10/18639 0.3 3.29310954063604 0.0556612695524923 0.372254848972449 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/1698 10/18639 0.3 3.29310954063604 0.0556612695524923 0.372254848972449 GO:0016427 tRNA (cytidine) methyltransferase activity 3/1698 10/18639 0.3 3.29310954063604 0.0556612695524923 0.372254848972449 GO:0070513 death domain binding 3/1698 10/18639 0.3 3.29310954063604 0.0556612695524923 0.372254848972449 GO:1905394 retromer complex binding 3/1698 10/18639 0.3 3.29310954063604 0.0556612695524923 0.372254848972449 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 7/1698 39/18639 0.179487179487179 1.97023647730362 0.0599094496505441 0.398363409457928 GO:0005518 collagen binding 11/1698 72/18639 0.152777777777778 1.67704652532391 0.060458583147889 0.399717604012043 GO:0048027 mRNA 5'-UTR binding 5/1698 24/18639 0.208333333333333 2.2868816254417 0.0615639805360374 0.402426697628222 GO:0060229 lipase activator activity 5/1698 24/18639 0.208333333333333 2.2868816254417 0.0615639805360374 0.402426697628222 GO:0004659 prenyltransferase activity 4/1698 17/18639 0.235294117647059 2.58283101226356 0.0625249955590572 0.40414201040128 GO:0070403 NAD+ binding 4/1698 17/18639 0.235294117647059 2.58283101226356 0.0625249955590572 0.40414201040128 GO:0019210 kinase inhibitor activity 13/1698 90/18639 0.144444444444444 1.58557126030624 0.0638662081920972 0.410517793768092 GO:0019208 phosphatase regulator activity 16/1698 117/18639 0.136752136752137 1.50113255413609 0.0653175343933195 0.417527001619175 GO:0140693 molecular condensate scaffold activity 8/1698 48/18639 0.166666666666667 1.82950530035336 0.066635024716011 0.422316398729513 GO:0061791 GTPase motor activity 7/1698 40/18639 0.175 1.92098056537102 0.0671618127625155 0.422316398729513 GO:1990606 membrane scission GTPase motor activity 7/1698 40/18639 0.175 1.92098056537102 0.0671618127625155 0.422316398729513 GO:0140713 histone chaperone activity 21/1698 164/18639 0.128048780487805 1.40559553563734 0.0698318325427849 0.430854292406304 GO:0008139 nuclear localization sequence binding 5/1698 25/18639 0.2 2.19540636042403 0.071423016275077 0.430854292406304 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/1698 25/18639 0.2 2.19540636042403 0.071423016275077 0.430854292406304 GO:0017025 TBP-class protein binding 5/1698 25/18639 0.2 2.19540636042403 0.071423016275077 0.430854292406304 GO:0019206 nucleoside kinase activity 3/1698 11/18639 0.272727272727273 2.99373594603277 0.0714987244096892 0.430854292406304 GO:0035252 UDP-xylosyltransferase activity 3/1698 11/18639 0.272727272727273 2.99373594603277 0.0714987244096892 0.430854292406304 GO:0042285 xylosyltransferase activity 3/1698 11/18639 0.272727272727273 2.99373594603277 0.0714987244096892 0.430854292406304 GO:0070990 snRNP binding 3/1698 11/18639 0.272727272727273 2.99373594603277 0.0714987244096892 0.430854292406304 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 17/1698 128/18639 0.1328125 1.45788703621908 0.0733120797402507 0.438814359538397 GO:0016763 pentosyltransferase activity 8/1698 49/18639 0.163265306122449 1.792168457489 0.0735782072173285 0.438814359538397 GO:0000400 four-way junction DNA binding 4/1698 18/18639 0.222222222222222 2.43934040047114 0.074813420762659 0.440002210306954 GO:0003746 translation elongation factor activity 4/1698 18/18639 0.222222222222222 2.43934040047114 0.074813420762659 0.440002210306954 GO:0140318 protein transporter activity 7/1698 41/18639 0.170731707317073 1.87412738084978 0.0749182674420657 0.440002210306954 GO:0051213 dioxygenase activity 13/1698 93/18639 0.139784946236559 1.53442380029636 0.0787004767487415 0.459881068678252 GO:0042054 histone methyltransferase activity 10/1698 67/18639 0.149253731343284 1.63836295554032 0.0808419818933596 0.465592978001547 GO:0004529 DNA exonuclease activity 5/1698 26/18639 0.192307692307692 2.11096765425387 0.0820924524739115 0.465592978001547 GO:0005112 Notch binding 5/1698 26/18639 0.192307692307692 2.11096765425387 0.0820924524739115 0.465592978001547 GO:0008198 ferrous iron binding 5/1698 26/18639 0.192307692307692 2.11096765425387 0.0820924524739115 0.465592978001547 GO:0034237 protein kinase A regulatory subunit binding 5/1698 26/18639 0.192307692307692 2.11096765425387 0.0820924524739115 0.465592978001547 GO:0050750 low-density lipoprotein particle receptor binding 5/1698 26/18639 0.192307692307692 2.11096765425387 0.0820924524739115 0.465592978001547 GO:0030332 cyclin binding 6/1698 34/18639 0.176470588235294 1.93712325919767 0.0839864925239263 0.474011570000891 GO:0008234 cysteine-type peptidase activity 23/1698 187/18639 0.122994652406417 1.35011621095595 0.0854428105925849 0.479889960464178 GO:0016830 carbon-carbon lyase activity 8/1698 51/18639 0.156862745098039 1.72188734150904 0.0887264823431782 0.4831529044468 GO:0004300 enoyl-CoA hydratase activity 3/1698 12/18639 0.25 2.74425795053004 0.0890942905470814 0.4831529044468 GO:0005078 MAP-kinase scaffold activity 3/1698 12/18639 0.25 2.74425795053004 0.0890942905470814 0.4831529044468 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/1698 12/18639 0.25 2.74425795053004 0.0890942905470814 0.4831529044468 GO:0035259 nuclear glucocorticoid receptor binding 3/1698 12/18639 0.25 2.74425795053004 0.0890942905470814 0.4831529044468 GO:0070679 inositol 1,4,5 trisphosphate binding 3/1698 12/18639 0.25 2.74425795053004 0.0890942905470814 0.4831529044468 GO:1990459 transferrin receptor binding 3/1698 12/18639 0.25 2.74425795053004 0.0890942905470814 0.4831529044468 GO:0140597 protein carrier chaperone 23/1698 188/18639 0.122340425531915 1.34293474174874 0.0893644957230901 0.4831529044468 GO:0141003 histone H2AX kinase activity 40/1698 354/18639 0.112994350282486 1.24034257651075 0.0909702284007823 0.489546763998628 GO:0008200 ion channel inhibitor activity 7/1698 43/18639 0.162790697674419 1.78695866546142 0.0919386589558114 0.492467724129045 GO:0008266 poly(U) RNA binding 5/1698 27/18639 0.185185185185185 2.03278366705929 0.0935548672392303 0.496527437595365 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 5/1698 27/18639 0.185185185185185 2.03278366705929 0.0935548672392303 0.496527437595365 GO:0016829 lyase activity 24/1698 200/18639 0.12 1.31724381625442 0.0992478899374323 0.524337025833832 GO:0140996 histone H3 kinase activity 40/1698 357/18639 0.112044817927171 1.22991952964932 0.0999634576618193 0.525028305825328 GO:0016887 ATP hydrolysis activity 46/1698 417/18639 0.11031175059952 1.21089559447848 0.100286896937728 0.525028305825328 GO:0001046 core promoter sequence-specific DNA binding 7/1698 44/18639 0.159090909090909 1.74634596851911 0.10119387398362 0.525028305825328 GO:0016248 channel inhibitor activity 7/1698 44/18639 0.159090909090909 1.74634596851911 0.10119387398362 0.525028305825328 GO:0016004 phospholipase activator activity 4/1698 20/18639 0.2 2.19540636042403 0.102687846980659 0.525707252020456 GO:0052745 inositol phosphate phosphatase activity 4/1698 20/18639 0.2 2.19540636042403 0.102687846980659 0.525707252020456 GO:0061608 nuclear import signal receptor activity 4/1698 20/18639 0.2 2.19540636042403 0.102687846980659 0.525707252020456 GO:0019787 ubiquitin-like protein transferase activity 52/1698 479/18639 0.108559498956159 1.19166107246398 0.104892217417949 0.529849706787666 GO:0016860 intramolecular oxidoreductase activity 8/1698 53/18639 0.150943396226415 1.65691046069738 0.10554534431036 0.529849706787666 GO:0051018 protein kinase A binding 8/1698 53/18639 0.150943396226415 1.65691046069738 0.10554534431036 0.529849706787666 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 5/1698 28/18639 0.178571428571429 1.9601842503786 0.105786760819318 0.529849706787666 GO:0097718 disordered domain specific binding 5/1698 28/18639 0.178571428571429 1.9601842503786 0.105786760819318 0.529849706787666 GO:0008170 N-methyltransferase activity 13/1698 98/18639 0.13265306122449 1.45613687170981 0.107958497130176 0.533143624248861 GO:0046975 histone H3K36 methyltransferase activity 3/1698 13/18639 0.230769230769231 2.53316118510465 0.108287598702232 0.533143624248861 GO:0051011 microtubule minus-end binding 3/1698 13/18639 0.230769230769231 2.53316118510465 0.108287598702232 0.533143624248861 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/1698 13/18639 0.230769230769231 2.53316118510465 0.108287598702232 0.533143624248861 GO:0003727 single-stranded RNA binding 12/1698 89/18639 0.134831460674157 1.48004923174654 0.108880446415427 0.533791002129867 GO:0035173 histone kinase activity 40/1698 360/18639 0.111111111111111 1.21967020023557 0.109530329470309 0.534711355262226 GO:0046915 transition metal ion transmembrane transporter activity 7/1698 45/18639 0.155555555555556 1.7075382803298 0.110935891238574 0.53480344234596 GO:0051539 4 iron, 4 sulfur cluster binding 7/1698 45/18639 0.155555555555556 1.7075382803298 0.110935891238574 0.53480344234596 GO:0141110 transporter inhibitor activity 7/1698 45/18639 0.155555555555556 1.7075382803298 0.110935891238574 0.53480344234596 GO:0003924 GTPase activity 37/1698 331/18639 0.11178247734139 1.22703980869621 0.112623586077658 0.540686676729667 GO:0019783 ubiquitin-like protein peptidase activity 16/1698 127/18639 0.125984251968504 1.38293314042458 0.114759900096742 0.548666133933598 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 4/1698 21/18639 0.19047619047619 2.09086320040384 0.118162329988159 0.553497229944535 GO:0019200 carbohydrate kinase activity 4/1698 21/18639 0.19047619047619 2.09086320040384 0.118162329988159 0.553497229944535 GO:0051010 microtubule plus-end binding 4/1698 21/18639 0.19047619047619 2.09086320040384 0.118162329988159 0.553497229944535 GO:0072542 protein phosphatase activator activity 4/1698 21/18639 0.19047619047619 2.09086320040384 0.118162329988159 0.553497229944535 GO:0140312 cargo adaptor activity 4/1698 21/18639 0.19047619047619 2.09086320040384 0.118162329988159 0.553497229944535 GO:0016755 aminoacyltransferase activity 53/1698 496/18639 0.106854838709677 1.17294896272655 0.124836347824223 0.580974814375323 GO:0043539 protein serine/threonine kinase activator activity 10/1698 73/18639 0.136986301369863 1.5037029865918 0.125114865961025 0.580974814375323 GO:0035591 signaling adaptor activity 16/1698 129/18639 0.124031007751938 1.36149231654203 0.126778683017405 0.580974814375323 GO:0043531 ADP binding 6/1698 38/18639 0.157894736842105 1.73321554770318 0.127368691908652 0.580974814375323 GO:0005545 1-phosphatidylinositol binding 3/1698 14/18639 0.214285714285714 2.35222110045432 0.128906404793781 0.580974814375323 GO:0016530 metallochaperone activity 3/1698 14/18639 0.214285714285714 2.35222110045432 0.128906404793781 0.580974814375323 GO:0030983 mismatched DNA binding 3/1698 14/18639 0.214285714285714 2.35222110045432 0.128906404793781 0.580974814375323 GO:0032454 histone H3K9 demethylase activity 3/1698 14/18639 0.214285714285714 2.35222110045432 0.128906404793781 0.580974814375323 GO:0046030 inositol trisphosphate phosphatase activity 3/1698 14/18639 0.214285714285714 2.35222110045432 0.128906404793781 0.580974814375323 GO:0043495 protein-membrane adaptor activity 7/1698 47/18639 0.148936170212766 1.63487707691151 0.131836938538722 0.580974814375323 GO:0061733 protein-lysine-acetyltransferase activity 7/1698 47/18639 0.148936170212766 1.63487707691151 0.131836938538722 0.580974814375323 GO:0001968 fibronectin binding 5/1698 30/18639 0.166666666666667 1.82950530035336 0.132438157739709 0.580974814375323 GO:0008106 alcohol dehydrogenase (NADP+) activity 5/1698 30/18639 0.166666666666667 1.82950530035336 0.132438157739709 0.580974814375323 GO:0008187 poly-pyrimidine tract binding 5/1698 30/18639 0.166666666666667 1.82950530035336 0.132438157739709 0.580974814375323 GO:0070566 adenylyltransferase activity 5/1698 30/18639 0.166666666666667 1.82950530035336 0.132438157739709 0.580974814375323 GO:0003684 damaged DNA binding 10/1698 74/18639 0.135135135135135 1.48338267596218 0.133569231549215 0.580974814375323 GO:0160215 deacylase activity 9/1698 65/18639 0.138461538461538 1.51989671106279 0.134212859945617 0.580974814375323 GO:0004407 histone deacetylase activity 4/1698 22/18639 0.181818181818182 1.99582396402184 0.134573250002236 0.580974814375323 GO:0008649 rRNA methyltransferase activity 4/1698 22/18639 0.181818181818182 1.99582396402184 0.134573250002236 0.580974814375323 GO:0033558 protein lysine deacetylase activity 4/1698 22/18639 0.181818181818182 1.99582396402184 0.134573250002236 0.580974814375323 GO:0140035 ubiquitin-like protein reader activity 4/1698 22/18639 0.181818181818182 1.99582396402184 0.134573250002236 0.580974814375323 GO:0003697 single-stranded DNA binding 15/1698 121/18639 0.12396694214876 1.36078906637853 0.136365794906281 0.586524998909172 GO:0051117 ATPase binding 11/1698 84/18639 0.130952380952381 1.43746845027764 0.140391819453788 0.601604944844564 GO:0019003 GDP binding 10/1698 75/18639 0.133333333333333 1.46360424028269 0.142319062931144 0.605184275127993 GO:0016504 peptidase activator activity 8/1698 57/18639 0.140350877192982 1.54063604240283 0.144016065682074 0.605184275127993 GO:0000510 H3-H4 histone complex chaperone activity 18/1698 151/18639 0.119205298013245 1.3085203472726 0.144365479632953 0.605184275127993 GO:0140584 chromatin extrusion motor activity 18/1698 151/18639 0.119205298013245 1.3085203472726 0.144365479632953 0.605184275127993 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 18/1698 151/18639 0.119205298013245 1.3085203472726 0.144365479632953 0.605184275127993 GO:0140849 ATP-dependent H2AZ histone chaperone activity 18/1698 151/18639 0.119205298013245 1.3085203472726 0.144365479632953 0.605184275127993 GO:0070325 lipoprotein particle receptor binding 5/1698 31/18639 0.161290322580645 1.77048900034196 0.146785693234912 0.607910720707513 GO:0015616 DNA translocase activity 18/1698 152/18639 0.118421052631579 1.29991166077739 0.150640172931872 0.607910720707513 GO:0140674 ATP-dependent histone chaperone activity 18/1698 152/18639 0.118421052631579 1.29991166077739 0.150640172931872 0.607910720707513 GO:0004129 cytochrome-c oxidase activity 3/1698 15/18639 0.2 2.19540636042403 0.150772487209078 0.607910720707513 GO:0008252 nucleotidase activity 3/1698 15/18639 0.2 2.19540636042403 0.150772487209078 0.607910720707513 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/1698 15/18639 0.2 2.19540636042403 0.150772487209078 0.607910720707513 GO:0017081 chloride channel regulator activity 3/1698 15/18639 0.2 2.19540636042403 0.150772487209078 0.607910720707513 GO:0061578 K63-linked deubiquitinase activity 3/1698 15/18639 0.2 2.19540636042403 0.150772487209078 0.607910720707513 GO:0141050 histone H3K deacetylase activity 3/1698 15/18639 0.2 2.19540636042403 0.150772487209078 0.607910720707513 GO:0141051 histone H4K deacetylase activity 3/1698 15/18639 0.2 2.19540636042403 0.150772487209078 0.607910720707513 GO:0051536 iron-sulfur cluster binding 10/1698 76/18639 0.131578947368421 1.44434628975265 0.151357950171443 0.607910720707513 GO:0005158 insulin receptor binding 4/1698 23/18639 0.173913043478261 1.90904900906437 0.151846325224262 0.607910720707513 GO:0017134 fibroblast growth factor binding 4/1698 23/18639 0.173913043478261 1.90904900906437 0.151846325224262 0.607910720707513 GO:0005096 GTPase activator activity 30/1698 271/18639 0.11070110701107 1.21516957219042 0.153086413804852 0.609809875299603 GO:0050840 extracellular matrix binding 9/1698 67/18639 0.134328358208955 1.47452665998629 0.153374826026089 0.609809875299603 GO:0044389 ubiquitin-like protein ligase binding 35/1698 322/18639 0.108695652173913 1.19315563066523 0.156299254126603 0.617747427282281 GO:0061775 cohesin loader activity 18/1698 153/18639 0.117647058823529 1.29141550613178 0.157062997812534 0.617747427282281 GO:0031625 ubiquitin protein ligase binding 33/1698 302/18639 0.109271523178808 1.19947698499988 0.1571027803501 0.617747427282281 GO:0050660 flavin adenine dinucleotide binding 11/1698 86/18639 0.127906976744186 1.40403895143397 0.157506906696865 0.617747427282281 GO:0051540 metal cluster binding 10/1698 77/18639 0.12987012987013 1.42558854572989 0.16067866831135 0.628058173095379 GO:0051059 NF-kappaB binding 5/1698 32/18639 0.15625 1.71516121908127 0.161760028148493 0.628336093756494 GO:0001221 transcription coregulator binding 14/1698 115/18639 0.121739130434783 1.33633430634506 0.161835916974447 0.628336093756494 GO:0016407 acetyltransferase activity 12/1698 96/18639 0.125 1.37212897526502 0.162437870930145 0.628563935338386 GO:0004879 nuclear receptor activity 8/1698 59/18639 0.135593220338983 1.4884110918129 0.165516202984125 0.636964182404958 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/1698 41/18639 0.146341463414634 1.60639489787124 0.165709782976571 0.636964182404958 GO:0000062 fatty-acyl-CoA binding 3/1698 16/18639 0.1875 2.05819346289753 0.173706351032963 0.656144252069917 GO:0008296 3'-5'-DNA exonuclease activity 3/1698 16/18639 0.1875 2.05819346289753 0.173706351032963 0.656144252069917 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/1698 16/18639 0.1875 2.05819346289753 0.173706351032963 0.656144252069917 GO:0016722 oxidoreductase activity, acting on metal ions 3/1698 16/18639 0.1875 2.05819346289753 0.173706351032963 0.656144252069917 GO:0016279 protein-lysine N-methyltransferase activity 9/1698 69/18639 0.130434782608696 1.43178675679828 0.173795379988968 0.656144252069917 GO:0016779 nucleotidyltransferase activity 16/1698 136/18639 0.117647058823529 1.29141550613178 0.174266162805991 0.656144252069917 GO:0019888 protein phosphatase regulator activity 13/1698 107/18639 0.121495327102804 1.33365806941647 0.174669342815501 0.656144252069917 GO:0098531 ligand-modulated transcription factor activity 8/1698 60/18639 0.133333333333333 1.46360424028269 0.176788329312644 0.661790716559166 GO:0071889 14-3-3 protein binding 5/1698 33/18639 0.151515151515152 1.66318663668487 0.177316440910407 0.661790716559166 GO:0004402 histone acetyltransferase activity 6/1698 42/18639 0.142857142857143 1.56814740030288 0.179465037678029 0.667656104802184 GO:0016835 carbon-oxygen lyase activity 10/1698 79/18639 0.126582278481013 1.3894976964709 0.180132851751396 0.667992658578093 GO:0016278 lysine N-methyltransferase activity 9/1698 70/18639 0.128571428571429 1.41133266027259 0.18445073540838 0.681819491589442 GO:0031490 chromatin DNA binding 15/1698 128/18639 0.1171875 1.28637091431095 0.18774809409994 0.68641698140343 GO:0000030 mannosyltransferase activity 4/1698 25/18639 0.16 1.75632508833922 0.188660847092732 0.68641698140343 GO:0004709 MAP kinase kinase kinase activity 4/1698 25/18639 0.16 1.75632508833922 0.188660847092732 0.68641698140343 GO:0017056 structural constituent of nuclear pore 4/1698 25/18639 0.16 1.75632508833922 0.188660847092732 0.68641698140343 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 4/1698 25/18639 0.16 1.75632508833922 0.188660847092732 0.68641698140343 GO:0140658 ATP-dependent chromatin remodeler activity 18/1698 158/18639 0.113924050632911 1.25054792682381 0.191323654717426 0.692894496538259 GO:0030159 signaling receptor complex adaptor activity 7/1698 52/18639 0.134615384615385 1.47767735797771 0.191638927305309 0.692894496538259 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 5/1698 34/18639 0.147058823529412 1.61426938266473 0.19340781132187 0.693693156978359 GO:0052866 phosphatidylinositol phosphate phosphatase activity 5/1698 34/18639 0.147058823529412 1.61426938266473 0.19340781132187 0.693693156978359 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/1698 43/18639 0.13953488372093 1.53167885610979 0.193658504497848 0.693693156978359 GO:0008484 sulfuric ester hydrolase activity 3/1698 17/18639 0.176470588235294 1.93712325919767 0.197530927205943 0.69693751902805 GO:0032183 SUMO binding 3/1698 17/18639 0.176470588235294 1.93712325919767 0.197530927205943 0.69693751902805 GO:0070492 oligosaccharide binding 3/1698 17/18639 0.176470588235294 1.93712325919767 0.197530927205943 0.69693751902805 GO:1901567 fatty acid derivative binding 3/1698 17/18639 0.176470588235294 1.93712325919767 0.197530927205943 0.69693751902805 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 25/1698 229/18639 0.109170305676856 1.19836591726202 0.197576064166984 0.69693751902805 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 11/1698 91/18639 0.120879120879121 1.32689395410243 0.204525842945531 0.712640191632356 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/1698 53/18639 0.132075471698113 1.44979665311021 0.204740124717584 0.712640191632356 GO:0034212 protein N-acetyltransferase activity 7/1698 53/18639 0.132075471698113 1.44979665311021 0.204740124717584 0.712640191632356 GO:0003689 DNA clamp loader activity 18/1698 160/18639 0.1125 1.23491607773852 0.205980792348757 0.712640191632356 GO:0030507 spectrin binding 4/1698 26/18639 0.153846153846154 1.6887741234031 0.208036918841608 0.712640191632356 GO:0070006 metalloaminopeptidase activity 4/1698 26/18639 0.153846153846154 1.6887741234031 0.208036918841608 0.712640191632356 GO:0097602 cullin family protein binding 4/1698 26/18639 0.153846153846154 1.6887741234031 0.208036918841608 0.712640191632356 GO:0003954 NADH dehydrogenase activity 6/1698 44/18639 0.136363636363636 1.49686797301638 0.208258183000094 0.712640191632356 GO:0043014 alpha-tubulin binding 6/1698 44/18639 0.136363636363636 1.49686797301638 0.208258183000094 0.712640191632356 GO:0140566 histone reader activity 5/1698 35/18639 0.142857142857143 1.56814740030288 0.209985195031543 0.712640191632356 GO:0003925 G protein activity 7/1698 54/18639 0.12962962962963 1.4229485669415 0.218169668694702 0.712640191632356 GO:0017069 snRNA binding 7/1698 54/18639 0.12962962962963 1.4229485669415 0.218169668694702 0.712640191632356 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 14/1698 122/18639 0.114754098360656 1.25965938712854 0.220012586920803 0.712640191632356 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 15/1698 132/18639 0.113636363636364 1.24738997751365 0.220768582569027 0.712640191632356 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1698 18/18639 0.166666666666667 1.82950530035336 0.2220744284946 0.712640191632356 GO:0004706 JUN kinase kinase kinase activity 3/1698 18/18639 0.166666666666667 1.82950530035336 0.2220744284946 0.712640191632356 GO:0008409 5'-3' exonuclease activity 3/1698 18/18639 0.166666666666667 1.82950530035336 0.2220744284946 0.712640191632356 GO:0015172 acidic amino acid transmembrane transporter activity 3/1698 18/18639 0.166666666666667 1.82950530035336 0.2220744284946 0.712640191632356 GO:0035615 clathrin adaptor activity 3/1698 18/18639 0.166666666666667 1.82950530035336 0.2220744284946 0.712640191632356 GO:0070628 proteasome binding 3/1698 18/18639 0.166666666666667 1.82950530035336 0.2220744284946 0.712640191632356 GO:0004536 DNA nuclease activity 8/1698 64/18639 0.125 1.37212897526502 0.224989357618827 0.712640191632356 GO:0004033 aldo-keto reductase (NADPH) activity 5/1698 36/18639 0.138888888888889 1.52458775029446 0.226998367288983 0.712640191632356 GO:0140030 modification-dependent protein binding 19/1698 173/18639 0.109826589595376 1.20556996670684 0.228337319468077 0.712640191632356 GO:0004090 carbonyl reductase (NADPH) activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0005131 growth hormone receptor binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0005381 iron ion transmembrane transporter activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0005522 profilin binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0005528 FK506 binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0008140 cAMP response element binding protein binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0008239 dipeptidyl-peptidase activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0015279 store-operated calcium channel activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0033204 ribonuclease P RNA binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0051864 histone H3K36 demethylase activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0051880 G-quadruplex DNA binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0097177 mitochondrial ribosome binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0099122 RNA polymerase II C-terminal domain binding 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0141109 transporter activator activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:1990757 ubiquitin ligase activator activity 2/1698 10/18639 0.2 2.19540636042403 0.22962114368853 0.712640191632356 GO:0003678 DNA helicase activity 9/1698 74/18639 0.121621621621622 1.33504440836596 0.229744850024951 0.712640191632356 GO:0048029 monosaccharide binding 9/1698 74/18639 0.121621621621622 1.33504440836596 0.229744850024951 0.712640191632356 GO:0019903 protein phosphatase binding 16/1698 144/18639 0.111111111111111 1.21967020023557 0.237923344344502 0.73402513669234 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/1698 46/18639 0.130434782608696 1.43178675679828 0.238542308899153 0.73402513669234 GO:0030276 clathrin binding 6/1698 46/18639 0.130434782608696 1.43178675679828 0.238542308899153 0.73402513669234 GO:0015078 proton transmembrane transporter activity 20/1698 185/18639 0.108108108108108 1.18670614076975 0.242522141115262 0.740440799764792 GO:0019213 deacetylase activity 5/1698 37/18639 0.135135135135135 1.48338267596218 0.244396331903963 0.740440799764792 GO:0019212 phosphatase inhibitor activity 7/1698 56/18639 0.125 1.37212897526502 0.245915820761474 0.740440799764792 GO:0015297 antiporter activity 15/1698 135/18639 0.111111111111111 1.21967020023557 0.247056943828627 0.740440799764792 GO:0003756 protein disulfide isomerase activity 3/1698 19/18639 0.157894736842105 1.73321554770318 0.247172501404931 0.740440799764792 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/1698 19/18639 0.157894736842105 1.73321554770318 0.247172501404931 0.740440799764792 GO:0031420 alkali metal ion binding 3/1698 19/18639 0.157894736842105 1.73321554770318 0.247172501404931 0.740440799764792 GO:0120227 acyl-CoA binding 3/1698 19/18639 0.157894736842105 1.73321554770318 0.247172501404931 0.740440799764792 GO:0101005 deubiquitinase activity 13/1698 115/18639 0.11304347826087 1.24088185589184 0.247350604303033 0.740440799764792 GO:0051019 mitogen-activated protein kinase binding 4/1698 28/18639 0.142857142857143 1.56814740030288 0.248306854199429 0.740440799764792 GO:0051537 2 iron, 2 sulfur cluster binding 4/1698 28/18639 0.142857142857143 1.56814740030288 0.248306854199429 0.740440799764792 GO:0141052 histone H3 demethylase activity 4/1698 28/18639 0.142857142857143 1.56814740030288 0.248306854199429 0.740440799764792 GO:0140938 histone H3 methyltransferase activity 6/1698 47/18639 0.127659574468085 1.40132320878129 0.254157728951899 0.75593956914485 GO:0008013 beta-catenin binding 12/1698 106/18639 0.113207547169811 1.24268284552303 0.257199558238576 0.756362207802444 GO:0015932 nucleobase-containing compound transmembrane transporter activity 7/1698 57/18639 0.12280701754386 1.34805653710247 0.26018178647259 0.756362207802444 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 8/1698 67/18639 0.119402985074627 1.31069036443226 0.26390684956872 0.756362207802444 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0002162 dystroglycan binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0032050 clathrin heavy chain binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0032404 mismatch repair complex binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0034056 estrogen response element binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0034511 U3 snoRNA binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0043522 leucine zipper domain binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0050786 RAGE receptor binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0097493 structural molecule activity conferring elasticity 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0140031 phosphorylation-dependent protein binding 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1698 11/18639 0.181818181818182 1.99582396402184 0.264759459083829 0.756362207802444 GO:0042826 histone deacetylase binding 14/1698 127/18639 0.110236220472441 1.21006649787151 0.266286319345971 0.75885042237263 GO:0035250 UDP-galactosyltransferase activity 4/1698 29/18639 0.137931034482759 1.51407335201657 0.269034487704013 0.760190243180757 GO:0016247 channel regulator activity 18/1698 168/18639 0.107142857142857 1.17611055022716 0.269382581463611 0.760190243180757 GO:0009378 four-way junction helicase activity 6/1698 48/18639 0.125 1.37212897526502 0.270041837001311 0.760190243180757 GO:0036121 double-stranded DNA helicase activity 6/1698 48/18639 0.125 1.37212897526502 0.270041837001311 0.760190243180757 GO:0043138 3'-5' DNA helicase activity 6/1698 48/18639 0.125 1.37212897526502 0.270041837001311 0.760190243180757 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1698 20/18639 0.15 1.64655477031802 0.272669793362156 0.760190243180757 GO:0016408 C-acyltransferase activity 3/1698 20/18639 0.15 1.64655477031802 0.272669793362156 0.760190243180757 GO:0030742 GTP-dependent protein binding 3/1698 20/18639 0.15 1.64655477031802 0.272669793362156 0.760190243180757 GO:0140664 ATP-dependent DNA damage sensor activity 3/1698 20/18639 0.15 1.64655477031802 0.272669793362156 0.760190243180757 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/1698 58/18639 0.120689655172414 1.3248141830145 0.27467513585467 0.762583767383282 GO:0140223 general transcription initiation factor activity 8/1698 68/18639 0.117647058823529 1.29141550613178 0.277303372086106 0.762583767383282 GO:1990841 promoter-specific chromatin binding 8/1698 68/18639 0.117647058823529 1.29141550613178 0.277303372086106 0.762583767383282 GO:0019902 phosphatase binding 20/1698 190/18639 0.105263157894737 1.15547703180212 0.281441290592816 0.762583767383282 GO:0140767 enzyme-substrate adaptor activity 15/1698 139/18639 0.107913669064748 1.18457177720721 0.283849844426991 0.762583767383282 GO:0001222 transcription corepressor binding 6/1698 49/18639 0.122448979591837 1.34412634311675 0.286159195628824 0.762583767383282 GO:0141108 transporter regulator activity 18/1698 170/18639 0.105882352941176 1.1622739555186 0.286264699710817 0.762583767383282 GO:0099106 ion channel regulator activity 17/1698 160/18639 0.10625 1.16630962897527 0.288653039638575 0.762583767383282 GO:0031593 polyubiquitin modification-dependent protein binding 7/1698 59/18639 0.11864406779661 1.30235970533629 0.289369607587243 0.762583767383282 GO:0015215 nucleotide transmembrane transporter activity 4/1698 30/18639 0.133333333333333 1.46360424028269 0.290049307698521 0.762583767383282 GO:0016769 transferase activity, transferring nitrogenous groups 4/1698 30/18639 0.133333333333333 1.46360424028269 0.290049307698521 0.762583767383282 GO:0032452 histone demethylase activity 4/1698 30/18639 0.133333333333333 1.46360424028269 0.290049307698521 0.762583767383282 GO:0051721 protein phosphatase 2A binding 4/1698 30/18639 0.133333333333333 1.46360424028269 0.290049307698521 0.762583767383282 GO:0008080 N-acetyltransferase activity 8/1698 69/18639 0.115942028985507 1.27269933937625 0.290878190721796 0.762583767383282 GO:0016798 hydrolase activity, acting on glycosyl bonds 14/1698 130/18639 0.107692307692308 1.18214188638217 0.295555144919815 0.762583767383282 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/1698 40/18639 0.125 1.37212897526502 0.298387064894339 0.762583767383282 GO:0030331 nuclear estrogen receptor binding 5/1698 40/18639 0.125 1.37212897526502 0.298387064894339 0.762583767383282 GO:0032451 demethylase activity 5/1698 40/18639 0.125 1.37212897526502 0.298387064894339 0.762583767383282 GO:0005123 death receptor binding 3/1698 21/18639 0.142857142857143 1.56814740030288 0.298421037257822 0.762583767383282 GO:0004526 ribonuclease P activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0004859 phospholipase inhibitor activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0005095 GTPase inhibitor activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0005527 macrolide binding 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0016423 tRNA (guanine) methyltransferase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0016801 hydrolase activity, acting on ether bonds 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0016803 ether hydrolase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0016840 carbon-nitrogen lyase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0031543 peptidyl-proline dioxygenase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0034452 dynactin binding 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0035497 cAMP response element binding 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0043047 single-stranded telomeric DNA binding 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0070008 serine-type exopeptidase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0097371 MDM2/MDM4 family protein binding 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:1990817 poly(A) RNA polymerase activity 2/1698 12/18639 0.166666666666667 1.82950530035336 0.299892492791178 0.762583767383282 GO:0015605 organophosphate ester transmembrane transporter activity 6/1698 50/18639 0.12 1.31724381625442 0.302474425197873 0.76578317276573 GO:0032813 tumor necrosis factor receptor superfamily binding 6/1698 50/18639 0.12 1.31724381625442 0.302474425197873 0.76578317276573 GO:0031072 heat shock protein binding 14/1698 131/18639 0.106870229007634 1.17311790251666 0.305519036784942 0.771802457554972 GO:0140457 protein demethylase activity 4/1698 31/18639 0.129032258064516 1.41639120027357 0.311273546878315 0.775868242355565 GO:0030695 GTPase regulator activity 48/1698 489/18639 0.098159509202454 1.07750005419584 0.313441484706757 0.775868242355565 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1698 41/18639 0.121951219512195 1.3386624148927 0.316814465160695 0.775868242355565 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/1698 41/18639 0.121951219512195 1.3386624148927 0.316814465160695 0.775868242355565 GO:0140299 molecular sensor activity 8/1698 71/18639 0.112676056338028 1.23684865376002 0.318480484629984 0.775868242355565 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 13/1698 122/18639 0.10655737704918 1.16968371661936 0.31860911291307 0.775868242355565 GO:0060589 nucleoside-triphosphatase regulator activity 48/1698 490/18639 0.0979591836734694 1.0753010744934 0.318669685269831 0.775868242355565 GO:0004857 enzyme inhibitor activity 41/1698 416/18639 0.0985576923076923 1.08187092280511 0.320498742714902 0.775868242355565 GO:0032931 histone H3K56 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0034062 5'-3' RNA polymerase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0043992 histone H3K9 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0043993 histone H3K18 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0043994 histone H3K23 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0043999 histone H2AK5 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0044012 histone H2AK9 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0044014 histone H2BK5 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0044015 histone H2BK12 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0044016 histone H3K4 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0044017 histone H3K27 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0044018 histone H3K36 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0046972 histone H4K16 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0061133 endopeptidase activator activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0097747 RNA polymerase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0140517 protein-RNA adaptor activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0140908 histone H3K122 acetyltransferase activity 3/1698 22/18639 0.136363636363636 1.49686797301638 0.324291740508704 0.775868242355565 GO:0008238 exopeptidase activity 11/1698 102/18639 0.107843137254902 1.18379754728747 0.324563724546321 0.775868242355565 GO:0008378 galactosyltransferase activity 4/1698 32/18639 0.125 1.37212897526502 0.332632620982575 0.777675334186775 GO:0031369 translation initiation factor binding 4/1698 32/18639 0.125 1.37212897526502 0.332632620982575 0.777675334186775 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0008253 5'-nucleotidase activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0009982 pseudouridine synthase activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0019104 DNA N-glycosylase activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0030955 potassium ion binding 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0031994 insulin-like growth factor I binding 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0035673 oligopeptide transmembrane transporter activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0043560 insulin receptor substrate binding 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0140666 annealing activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0140852 histone ubiquitin ligase activity 2/1698 13/18639 0.153846153846154 1.6887741234031 0.334729746261896 0.777675334186775 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 6/1698 52/18639 0.115384615384615 1.26658059255232 0.335558523228448 0.778038499750129 GO:0008194 UDP-glycosyltransferase activity 15/1698 145/18639 0.103448275862069 1.13555501401243 0.341946447874937 0.791264080382604 GO:0004521 RNA endonuclease activity 8/1698 73/18639 0.10958904109589 1.20296238927344 0.346549085084673 0.798522928897113 GO:0000295 adenine nucleotide transmembrane transporter activity 3/1698 23/18639 0.130434782608696 1.43178675679828 0.35015855280137 0.798522928897113 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1698 23/18639 0.130434782608696 1.43178675679828 0.35015855280137 0.798522928897113 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/1698 23/18639 0.130434782608696 1.43178675679828 0.35015855280137 0.798522928897113 GO:0044013 histone H2B acetyltransferase activity 3/1698 23/18639 0.130434782608696 1.43178675679828 0.35015855280137 0.798522928897113 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/1698 23/18639 0.130434782608696 1.43178675679828 0.35015855280137 0.798522928897113 GO:0016410 N-acyltransferase activity 10/1698 94/18639 0.106382978723404 1.16776934065108 0.352196287258031 0.798522928897113 GO:0004864 protein phosphatase inhibitor activity 6/1698 53/18639 0.113207547169811 1.24268284552303 0.352258744314941 0.798522928897113 GO:0005246 calcium channel regulator activity 6/1698 53/18639 0.113207547169811 1.24268284552303 0.352258744314941 0.798522928897113 GO:0016874 ligase activity 17/1698 167/18639 0.101796407185629 1.11742239901822 0.35230418314496 0.798522928897113 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1698 43/18639 0.116279069767442 1.27639904675816 0.354022132039358 0.798522928897113 GO:0048156 tau protein binding 5/1698 43/18639 0.116279069767442 1.27639904675816 0.354022132039358 0.798522928897113 GO:0140416 transcription regulator inhibitor activity 4/1698 33/18639 0.121212121212121 1.3305493093479 0.35405554237184 0.798522928897113 GO:0002020 protease binding 14/1698 136/18639 0.102941176470588 1.12998856786531 0.356552641228421 0.801031856118996 GO:0019838 growth factor binding 14/1698 136/18639 0.102941176470588 1.12998856786531 0.356552641228421 0.801031856118996 GO:0004065 arylsulfatase activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0005161 platelet-derived growth factor receptor binding 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0005313 L-glutamate transmembrane transporter activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0008174 mRNA methyltransferase activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0008191 metalloendopeptidase inhibitor activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0008494 translation activator activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0015926 glucosidase activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0034236 protein kinase A catalytic subunit binding 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0044548 S100 protein binding 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0070742 C2H2 zinc finger domain binding 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0071933 Arp2/3 complex binding 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0098599 palmitoyl hydrolase activity 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0098847 sequence-specific single stranded DNA binding 2/1698 14/18639 0.142857142857143 1.56814740030288 0.369033636506582 0.80409023999645 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1698 44/18639 0.113636363636364 1.24738997751365 0.372709817813623 0.808019706081932 GO:0044183 protein folding chaperone 8/1698 75/18639 0.106666666666667 1.17088339222615 0.374920980262559 0.808019706081932 GO:0004622 lysophospholipase activity 3/1698 24/18639 0.125 1.37212897526502 0.375909375464151 0.808019706081932 GO:0005540 hyaluronic acid binding 3/1698 24/18639 0.125 1.37212897526502 0.375909375464151 0.808019706081932 GO:0035035 histone acetyltransferase binding 3/1698 24/18639 0.125 1.37212897526502 0.375909375464151 0.808019706081932 GO:0043998 histone H2A acetyltransferase activity 3/1698 24/18639 0.125 1.37212897526502 0.375909375464151 0.808019706081932 GO:0140612 DNA damage sensor activity 3/1698 24/18639 0.125 1.37212897526502 0.375909375464151 0.808019706081932 GO:0061659 ubiquitin-like protein ligase activity 36/1698 372/18639 0.0967741935483871 1.06229340020517 0.376424046307832 0.808019706081932 GO:0016757 glycosyltransferase activity 26/1698 267/18639 0.0973782771535581 1.06892444515028 0.390320866450312 0.836298597190761 GO:0019842 vitamin binding 15/1698 150/18639 0.1 1.09770318021201 0.392089995920648 0.838536275933807 GO:0010485 histone H4 acetyltransferase activity 4/1698 35/18639 0.114285714285714 1.2545179202423 0.396828794014669 0.840834660673414 GO:0003707 nuclear steroid receptor activity 3/1698 25/18639 0.12 1.31724381625442 0.401443265696617 0.840834660673414 GO:0008483 transaminase activity 3/1698 25/18639 0.12 1.31724381625442 0.401443265696617 0.840834660673414 GO:0047617 fatty acyl-CoA hydrolase activity 3/1698 25/18639 0.12 1.31724381625442 0.401443265696617 0.840834660673414 GO:0030170 pyridoxal phosphate binding 6/1698 56/18639 0.107142857142857 1.17611055022716 0.402596932351113 0.840834660673414 GO:0008242 omega peptidase activity 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0016846 carbon-sulfur lyase activity 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0031005 filamin binding 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0033130 acetylcholine receptor binding 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0047372 monoacylglycerol lipase activity 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0050780 dopamine receptor binding 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0140776 protein-containing complex destabilizing activity 2/1698 15/18639 0.133333333333333 1.46360424028269 0.402612274860044 0.840834660673414 GO:0016651 oxidoreductase activity, acting on NAD(P)H 9/1698 88/18639 0.102272727272727 1.12265097976229 0.409771562050181 0.854244499625332 GO:0008237 metallopeptidase activity 18/1698 184/18639 0.0978260869565217 1.07384006759871 0.41174290741995 0.856810330728206 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1698 36/18639 0.111111111111111 1.21967020023557 0.41805759735538 0.8683889410057 GO:0070279 vitamin B6 binding 6/1698 57/18639 0.105263157894737 1.15547703180212 0.419351655395645 0.869515887621436 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1698 26/18639 0.115384615384615 1.26658059255232 0.426670180503792 0.879221672436734 GO:0015216 purine nucleotide transmembrane transporter activity 3/1698 26/18639 0.115384615384615 1.26658059255232 0.426670180503792 0.879221672436734 GO:0016289 acyl-CoA hydrolase activity 3/1698 26/18639 0.115384615384615 1.26658059255232 0.426670180503792 0.879221672436734 GO:0005504 fatty acid binding 5/1698 47/18639 0.106382978723404 1.16776934065108 0.428592068499843 0.879221672436734 GO:0061749 forked DNA-dependent helicase activity 5/1698 47/18639 0.106382978723404 1.16776934065108 0.428592068499843 0.879221672436734 GO:1990518 single-stranded 3'-5' DNA helicase activity 5/1698 47/18639 0.106382978723404 1.16776934065108 0.428592068499843 0.879221672436734 GO:0004708 MAP kinase kinase activity 2/1698 16/18639 0.125 1.37212897526502 0.435313121121056 0.882061788331106 GO:0030275 LRR domain binding 2/1698 16/18639 0.125 1.37212897526502 0.435313121121056 0.882061788331106 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1698 16/18639 0.125 1.37212897526502 0.435313121121056 0.882061788331106 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1698 16/18639 0.125 1.37212897526502 0.435313121121056 0.882061788331106 GO:0055102 lipase inhibitor activity 2/1698 16/18639 0.125 1.37212897526502 0.435313121121056 0.882061788331106 GO:0097027 ubiquitin-protein transferase activator activity 2/1698 16/18639 0.125 1.37212897526502 0.435313121121056 0.882061788331106 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/1698 16/18639 0.125 1.37212897526502 0.435313121121056 0.882061788331106 GO:0004364 glutathione transferase activity 3/1698 27/18639 0.111111111111111 1.21967020023557 0.451510597959339 0.908517846676445 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/1698 27/18639 0.111111111111111 1.21967020023557 0.451510597959339 0.908517846676445 GO:0005104 fibroblast growth factor receptor binding 3/1698 27/18639 0.111111111111111 1.21967020023557 0.451510597959339 0.908517846676445 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1698 27/18639 0.111111111111111 1.21967020023557 0.451510597959339 0.908517846676445 GO:0015459 potassium channel regulator activity 6/1698 59/18639 0.101694915254237 1.11630831885968 0.45264987267929 0.909228997725588 GO:0097110 scaffold protein binding 7/1698 70/18639 0.1 1.09770318021201 0.456915208327263 0.916206058985518 GO:0030971 receptor tyrosine kinase binding 8/1698 81/18639 0.0987654320987654 1.08415128909829 0.460301318680803 0.917383951757271 GO:0052689 carboxylic ester hydrolase activity 9/1698 92/18639 0.0978260869565217 1.07384006759871 0.463078971493277 0.917383951757271 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0004549 tRNA-specific ribonuclease activity 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0016018 cyclosporin A binding 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0032977 membrane insertase activity 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0046965 nuclear retinoid X receptor binding 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0048038 quinone binding 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0051787 misfolded protein binding 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:1990226 histone methyltransferase binding 2/1698 17/18639 0.117647058823529 1.29141550613178 0.46701741364307 0.917383951757271 GO:0036408 histone H3K14 acetyltransferase activity 3/1698 28/18639 0.107142857142857 1.17611055022716 0.475895047210528 0.931659170258175 GO:0050698 proteoglycan sulfotransferase activity 3/1698 28/18639 0.107142857142857 1.17611055022716 0.475895047210528 0.931659170258175 GO:0000217 DNA secondary structure binding 4/1698 39/18639 0.102564102564103 1.12584941560207 0.480475669261855 0.939037752256699 GO:0030246 carbohydrate binding 26/1698 280/18639 0.0928571428571429 1.01929581019687 0.489559463712404 0.952827057616393 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1698 18/18639 0.111111111111111 1.21967020023557 0.497635286786629 0.952827057616393 GO:0008525 phosphatidylcholine transporter activity 2/1698 18/18639 0.111111111111111 1.21967020023557 0.497635286786629 0.952827057616393 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1698 18/18639 0.111111111111111 1.21967020023557 0.497635286786629 0.952827057616393 GO:0016854 racemase and epimerase activity 2/1698 18/18639 0.111111111111111 1.21967020023557 0.497635286786629 0.952827057616393 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1698 18/18639 0.111111111111111 1.21967020023557 0.497635286786629 0.952827057616393 GO:0070064 proline-rich region binding 2/1698 18/18639 0.111111111111111 1.21967020023557 0.497635286786629 0.952827057616393 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1698 18/18639 0.111111111111111 1.21967020023557 0.497635286786629 0.952827057616393 GO:0010484 histone H3 acetyltransferase activity 3/1698 29/18639 0.103448275862069 1.13555501401243 0.499763573307434 0.952827057616393 GO:0016417 S-acyltransferase activity 3/1698 29/18639 0.103448275862069 1.13555501401243 0.499763573307434 0.952827057616393 GO:0043236 laminin binding 3/1698 29/18639 0.103448275862069 1.13555501401243 0.499763573307434 0.952827057616393 GO:0099604 ligand-gated calcium channel activity 3/1698 29/18639 0.103448275862069 1.13555501401243 0.499763573307434 0.952827057616393 GO:0106222 lncRNA binding 3/1698 29/18639 0.103448275862069 1.13555501401243 0.499763573307434 0.952827057616393 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/1698 40/18639 0.1 1.09770318021201 0.500707736413801 0.952827057616393 GO:0050997 quaternary ammonium group binding 4/1698 40/18639 0.1 1.09770318021201 0.500707736413801 0.952827057616393 GO:0071949 FAD binding 4/1698 40/18639 0.1 1.09770318021201 0.500707736413801 0.952827057616393 GO:1990782 protein tyrosine kinase binding 11/1698 117/18639 0.094017094017094 1.03202863096856 0.502871680326535 0.955373619273893 GO:0035064 methylated histone binding 7/1698 74/18639 0.0945945945945946 1.03836787317353 0.516756440812234 0.972657786019276 GO:0004842 ubiquitin-protein transferase activity 41/1698 449/18639 0.0913140311804009 1.00235702424705 0.518124592310659 0.972657786019276 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1698 41/18639 0.0975609756097561 1.07092993191416 0.520588090062785 0.972657786019276 GO:0042169 SH2 domain binding 4/1698 41/18639 0.0975609756097561 1.07092993191416 0.520588090062785 0.972657786019276 GO:0031624 ubiquitin conjugating enzyme binding 3/1698 30/18639 0.1 1.09770318021201 0.523065158375091 0.972657786019276 GO:0043995 histone H4K5 acetyltransferase activity 3/1698 30/18639 0.1 1.09770318021201 0.523065158375091 0.972657786019276 GO:0043996 histone H4K8 acetyltransferase activity 3/1698 30/18639 0.1 1.09770318021201 0.523065158375091 0.972657786019276 GO:0043997 histone H4K12 acetyltransferase activity 3/1698 30/18639 0.1 1.09770318021201 0.523065158375091 0.972657786019276 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0005520 insulin-like growth factor binding 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0008301 DNA binding, bending 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0030506 ankyrin binding 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0042800 histone H3K4 methyltransferase activity 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0043395 heparan sulfate proteoglycan binding 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0046527 glucosyltransferase activity 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0070003 threonine-type peptidase activity 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:0140036 ubiquitin-modified protein reader activity 2/1698 19/18639 0.105263157894737 1.15547703180212 0.527101496831535 0.972657786019276 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1698 53/18639 0.0943396226415094 1.03556903793586 0.536264913797943 0.987991250420733 GO:0005164 tumor necrosis factor receptor binding 3/1698 31/18639 0.0967741935483871 1.06229340020517 0.545757116749746 0.99758231203923 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/1698 31/18639 0.0967741935483871 1.06229340020517 0.545757116749746 0.99758231203923 GO:0016878 acid-thiol ligase activity 3/1698 31/18639 0.0967741935483871 1.06229340020517 0.545757116749746 0.99758231203923 GO:0047499 calcium-independent phospholipase A2 activity 3/1698 31/18639 0.0967741935483871 1.06229340020517 0.545757116749746 0.99758231203923 GO:0140034 methylation-dependent protein binding 7/1698 76/18639 0.0921052631578947 1.01104240282686 0.545781852654134 0.99758231203923 GO:0015399 primary active transmembrane transporter activity 15/1698 166/18639 0.0903614457831325 0.991900464047001 0.552822257184786 0.999999999989978 GO:0050661 NADP binding 5/1698 54/18639 0.0925925925925926 1.01639183352964 0.553330733699012 0.999999999989978 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/1698 20/18639 0.1 1.09770318021201 0.55537168610591 0.999999999989978 GO:0016505 peptidase activator activity involved in apoptotic process 2/1698 20/18639 0.1 1.09770318021201 0.55537168610591 0.999999999989978 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1698 20/18639 0.1 1.09770318021201 0.55537168610591 0.999999999989978 GO:0042288 MHC class I protein binding 2/1698 20/18639 0.1 1.09770318021201 0.55537168610591 0.999999999989978 GO:0140939 histone H4 methyltransferase activity 2/1698 20/18639 0.1 1.09770318021201 0.55537168610591 0.999999999989978 GO:0008235 metalloexopeptidase activity 6/1698 66/18639 0.0909090909090909 0.997911982010922 0.564404535483906 0.999999999989978 GO:0043425 bHLH transcription factor binding 3/1698 32/18639 0.09375 1.02909673144876 0.567804478380832 0.999999999989978 GO:0051087 protein-folding chaperone binding 12/1698 134/18639 0.0895522388059701 0.983017773324192 0.568896381884288 0.999999999989978 GO:0140313 molecular sequestering activity 5/1698 55/18639 0.0909090909090909 0.997911982010922 0.570082840029404 0.999999999989978 GO:0001223 transcription coactivator binding 4/1698 44/18639 0.0909090909090909 0.997911982010922 0.577813236616623 0.999999999989978 GO:0016790 thiolester hydrolase activity 4/1698 44/18639 0.0909090909090909 0.997911982010922 0.577813236616623 0.999999999989978 GO:0008373 sialyltransferase activity 2/1698 21/18639 0.0952380952380952 1.04543160020192 0.582419122826762 0.999999999989978 GO:0036122 BMP binding 2/1698 21/18639 0.0952380952380952 1.04543160020192 0.582419122826762 0.999999999989978 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1698 21/18639 0.0952380952380952 1.04543160020192 0.582419122826762 0.999999999989978 GO:0061891 calcium ion sensor activity 2/1698 21/18639 0.0952380952380952 1.04543160020192 0.582419122826762 0.999999999989978 GO:0070182 DNA polymerase binding 2/1698 21/18639 0.0952380952380952 1.04543160020192 0.582419122826762 0.999999999989978 GO:0030296 protein tyrosine kinase activator activity 3/1698 33/18639 0.0909090909090909 0.997911982010922 0.589179371981732 0.999999999989978 GO:0032934 sterol binding 6/1698 68/18639 0.0882352941176471 0.968561629598836 0.594306214177927 0.999999999989978 GO:0004722 protein serine/threonine phosphatase activity 9/1698 103/18639 0.087378640776699 0.959158118631857 0.602484663124994 0.999999999989978 GO:0008970 phospholipase A1 activity 2/1698 22/18639 0.0909090909090909 0.997911982010922 0.608231861058568 0.999999999989978 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1698 22/18639 0.0909090909090909 0.997911982010922 0.608231861058568 0.999999999989978 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1698 22/18639 0.0909090909090909 0.997911982010922 0.608231861058568 0.999999999989978 GO:0050321 tau-protein kinase activity 2/1698 22/18639 0.0909090909090909 0.997911982010922 0.608231861058568 0.999999999989978 GO:0140784 metal ion sensor activity 2/1698 22/18639 0.0909090909090909 0.997911982010922 0.608231861058568 0.999999999989978 GO:0008376 acetylgalactosaminyltransferase activity 3/1698 34/18639 0.0882352941176471 0.968561629598836 0.609860417027205 0.999999999989978 GO:0015035 protein-disulfide reductase activity 3/1698 34/18639 0.0882352941176471 0.968561629598836 0.609860417027205 0.999999999989978 GO:0051427 hormone receptor binding 3/1698 34/18639 0.0882352941176471 0.968561629598836 0.609860417027205 0.999999999989978 GO:0033192 calmodulin-dependent protein phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:0140791 histone H2AXS140 phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/1698 81/18639 0.0864197530864197 0.948632377961 0.61480361554558 0.999999999989978 GO:0004519 endonuclease activity 11/1698 127/18639 0.0866141732283465 0.950766534041902 0.615151560597898 0.999999999989978 GO:0000182 rDNA binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0004382 GDP phosphatase activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0005031 tumor necrosis factor receptor activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0005337 nucleoside transmembrane transporter activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0005345 purine nucleobase transmembrane transporter activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0008190 eukaryotic initiation factor 4E binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0015643 toxic substance binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0030957 Tat protein binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0031996 thioesterase binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0032356 oxidized DNA binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0035374 chondroitin sulfate binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0042975 peroxisome proliferator activated receptor binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0043208 glycosphingolipid binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0043295 glutathione binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0050308 sugar-phosphatase activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0050815 phosphoserine residue binding 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0140940 histone H2A methyltransferase activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0140999 histone H3K4 trimethyltransferase activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:1990259 histone H2AQ104 methyltransferase activity 1/1698 10/18639 0.1 1.09770318021201 0.615355779810516 0.999999999989978 GO:0017116 single-stranded DNA helicase activity 5/1698 58/18639 0.0862068965517241 0.946295845010357 0.618285668140631 0.999999999989978 GO:0051219 phosphoprotein binding 8/1698 93/18639 0.0860215053763441 0.944260800182378 0.620483729366128 0.999999999989978 GO:0005085 guanyl-nucleotide exchange factor activity 20/1698 230/18639 0.0869565217391304 0.954524504532186 0.620662693862985 0.999999999989978 GO:0015291 secondary active transmembrane transporter activity 25/1698 287/18639 0.0871080139372822 0.956187439209072 0.623847989331255 0.999999999989978 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 7/1698 82/18639 0.0853658536585366 0.93706369042489 0.627909863839956 0.999999999989978 GO:0033549 MAP kinase phosphatase activity 7/1698 82/18639 0.0853658536585366 0.93706369042489 0.627909863839956 0.999999999989978 GO:0016758 hexosyltransferase activity 17/1698 197/18639 0.0862944162436548 0.947256551451992 0.629483650370405 0.999999999989978 GO:0004623 phospholipase A2 activity 3/1698 35/18639 0.0857142857142857 0.940888440181726 0.629832131684631 0.999999999989978 GO:0022804 active transmembrane transporter activity 40/1698 457/18639 0.087527352297593 0.960790529726052 0.630064258046669 0.999999999989978 GO:0004602 glutathione peroxidase activity 2/1698 23/18639 0.0869565217391304 0.954524504532186 0.632810271368777 0.999999999989978 GO:0043274 phospholipase binding 2/1698 23/18639 0.0869565217391304 0.954524504532186 0.632810271368777 0.999999999989978 GO:0099186 structural constituent of postsynapse 2/1698 23/18639 0.0869565217391304 0.954524504532186 0.632810271368777 0.999999999989978 GO:0140103 catalytic activity, acting on a glycoprotein 2/1698 23/18639 0.0869565217391304 0.954524504532186 0.632810271368777 0.999999999989978 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/1698 83/18639 0.0843373493975904 0.925773766443867 0.640762226734722 0.999999999989978 GO:0022853 active monoatomic ion transmembrane transporter activity 10/1698 118/18639 0.0847457627118644 0.930256932383063 0.641891188074114 0.999999999989978 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1698 48/18639 0.0833333333333333 0.914752650176678 0.64765029637094 0.999999999989978 GO:0016409 palmitoyltransferase activity 3/1698 36/18639 0.0833333333333333 0.914752650176678 0.649084362078199 0.999999999989978 GO:0055106 ubiquitin-protein transferase regulator activity 3/1698 36/18639 0.0833333333333333 0.914752650176678 0.649084362078199 0.999999999989978 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0004016 adenylate cyclase activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0005536 D-glucose binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0008199 ferric iron binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0008432 JUN kinase binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0008526 phosphatidylinositol transfer activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0015205 nucleobase transmembrane transporter activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0015217 ADP transmembrane transporter activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0019107 myristoyltransferase activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0019203 carbohydrate phosphatase activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0019215 intermediate filament binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0019864 IgG binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0032794 GTPase activating protein binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0048185 activin binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0050998 nitric-oxide synthase binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0140537 transcription regulator activator activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:1900750 oligopeptide binding 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:1990948 ubiquitin ligase inhibitor activity 1/1698 11/18639 0.0909090909090909 0.997911982010922 0.650415411883184 0.999999999989978 GO:0017018 myosin phosphatase activity 7/1698 84/18639 0.0833333333333333 0.914752650176678 0.653353577674019 0.999999999989978 GO:0004175 endopeptidase activity 35/1698 405/18639 0.0864197530864197 0.948632377961 0.655094725849619 0.999999999989978 GO:0015149 hexose transmembrane transporter activity 2/1698 24/18639 0.0833333333333333 0.914752650176678 0.656164898269197 0.999999999989978 GO:0015295 solute:proton symporter activity 2/1698 24/18639 0.0833333333333333 0.914752650176678 0.656164898269197 0.999999999989978 GO:0030552 cAMP binding 2/1698 24/18639 0.0833333333333333 0.914752650176678 0.656164898269197 0.999999999989978 GO:0050431 transforming growth factor beta binding 2/1698 24/18639 0.0833333333333333 0.914752650176678 0.656164898269197 0.999999999989978 GO:0050699 WW domain binding 2/1698 24/18639 0.0833333333333333 0.914752650176678 0.656164898269197 0.999999999989978 GO:0055056 D-glucose transmembrane transporter activity 2/1698 24/18639 0.0833333333333333 0.914752650176678 0.656164898269197 0.999999999989978 GO:0070840 dynein complex binding 2/1698 24/18639 0.0833333333333333 0.914752650176678 0.656164898269197 0.999999999989978 GO:0004843 cysteine-type deubiquitinase activity 9/1698 108/18639 0.0833333333333333 0.914752650176678 0.659619917613044 0.999999999989978 GO:0043394 proteoglycan binding 3/1698 37/18639 0.0810810810810811 0.890029605577309 0.667611736875117 0.999999999989978 GO:0004620 phospholipase activity 9/1698 109/18639 0.0825688073394495 0.906360424028269 0.670456614944343 0.999999999989978 GO:0005201 extracellular matrix structural constituent 14/1698 168/18639 0.0833333333333333 0.914752650176678 0.67642048041189 0.999999999989978 GO:0015179 L-amino acid transmembrane transporter activity 5/1698 62/18639 0.0806451612903226 0.885244500170979 0.67729922791907 0.999999999989978 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1698 25/18639 0.08 0.878162544169611 0.678314605449421 0.999999999989978 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1698 25/18639 0.08 0.878162544169611 0.678314605449421 0.999999999989978 GO:0019707 protein-cysteine S-acyltransferase activity 2/1698 25/18639 0.08 0.878162544169611 0.678314605449421 0.999999999989978 GO:0004000 adenosine deaminase activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0004032 aldose reductase (NADPH) activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0004126 cytidine deaminase activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0005025 transforming growth factor beta receptor activity, type I 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0005026 transforming growth factor beta receptor activity, type II 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0005165 neurotrophin receptor binding 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0005247 voltage-gated chloride channel activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0015166 polyol transmembrane transporter activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0015368 calcium:monoatomic cation antiporter activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0016361 activin receptor activity, type I 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0016362 activin receptor activity, type II 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0017002 activin receptor activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0035251 UDP-glucosyltransferase activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0036009 protein-glutamine N-methyltransferase activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0042301 phosphate ion binding 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0070410 co-SMAD binding 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1698 12/18639 0.0833333333333333 0.914752650176678 0.682281131800639 0.999999999989978 GO:0016791 phosphatase activity 23/1698 273/18639 0.0842490842490843 0.924804877101697 0.684667505189002 0.999999999989978 GO:0005109 frizzled binding 3/1698 38/18639 0.0789473684210526 0.86660777385159 0.685413150011316 0.999999999989978 GO:0042887 amide transmembrane transporter activity 3/1698 38/18639 0.0789473684210526 0.86660777385159 0.685413150011316 0.999999999989978 GO:1902936 phosphatidylinositol bisphosphate binding 9/1698 111/18639 0.0810810810810811 0.890029605577309 0.691503493823407 0.999999999989978 GO:0030544 Hsp70 protein binding 4/1698 51/18639 0.0784313725490196 0.860943670754521 0.694722614766836 0.999999999989978 GO:0008236 serine-type peptidase activity 16/1698 194/18639 0.0824742268041237 0.905322210484135 0.698793235184914 0.999999999989978 GO:0004435 phosphatidylinositol phospholipase C activity 2/1698 26/18639 0.0769230769230769 0.844387061701549 0.69928497419489 0.999999999989978 GO:0015145 monosaccharide transmembrane transporter activity 2/1698 26/18639 0.0769230769230769 0.844387061701549 0.69928497419489 0.999999999989978 GO:0019865 immunoglobulin binding 2/1698 26/18639 0.0769230769230769 0.844387061701549 0.69928497419489 0.999999999989978 GO:0051139 metal cation:proton antiporter activity 2/1698 26/18639 0.0769230769230769 0.844387061701549 0.69928497419489 0.999999999989978 GO:0120014 phospholipid transfer activity 2/1698 26/18639 0.0769230769230769 0.844387061701549 0.69928497419489 0.999999999989978 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1698 39/18639 0.0769230769230769 0.844387061701549 0.702491273407104 0.999999999989978 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1698 39/18639 0.0769230769230769 0.844387061701549 0.702491273407104 0.999999999989978 GO:0044325 transmembrane transporter binding 11/1698 136/18639 0.0808823529411765 0.8878481604656 0.704312144177244 0.999999999989978 GO:0140789 histone phosphatase activity 11/1698 136/18639 0.0808823529411765 0.8878481604656 0.704312144177244 0.999999999989978 GO:0002161 aminoacyl-tRNA editing activity 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0005035 death receptor activity 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0005542 folic acid binding 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0019855 calcium channel inhibitor activity 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0032396 inhibitory MHC class I receptor activity 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0046974 histone H3K9 methyltransferase activity 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0070123 transforming growth factor beta receptor activity, type III 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0071837 HMG box domain binding 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0089720 caspase binding 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0097157 pre-mRNA intronic binding 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0140333 glycerophospholipid flippase activity 1/1698 13/18639 0.0769230769230769 0.844387061701549 0.711243747262201 0.999999999989978 GO:0120013 lipid transfer activity 5/1698 65/18639 0.0769230769230769 0.844387061701549 0.717358454747739 0.999999999989978 GO:0015036 disulfide oxidoreductase activity 3/1698 40/18639 0.075 0.823277385159011 0.718852100730886 0.999999999989978 GO:0001671 ATPase activator activity 2/1698 27/18639 0.0740740740740741 0.813113466823714 0.719106924293735 0.999999999989978 GO:0015252 proton channel activity 2/1698 27/18639 0.0740740740740741 0.813113466823714 0.719106924293735 0.999999999989978 GO:0008146 sulfotransferase activity 4/1698 53/18639 0.0754716981132075 0.82845523034869 0.72350536756492 0.999999999989978 GO:0017171 serine hydrolase activity 16/1698 198/18639 0.0808080808080808 0.887032872898597 0.728957741391578 0.999999999989978 GO:0070851 growth factor receptor binding 11/1698 139/18639 0.079136690647482 0.868685969951954 0.730968800670278 0.999999999989978 GO:0001530 lipopolysaccharide binding 3/1698 41/18639 0.0731707317073171 0.80319744893562 0.734504522625736 0.999999999989978 GO:0004812 aminoacyl-tRNA ligase activity 3/1698 41/18639 0.0731707317073171 0.80319744893562 0.734504522625736 0.999999999989978 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/1698 41/18639 0.0731707317073171 0.80319744893562 0.734504522625736 0.999999999989978 GO:0017080 sodium channel regulator activity 3/1698 41/18639 0.0731707317073171 0.80319744893562 0.734504522625736 0.999999999989978 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1698 41/18639 0.0731707317073171 0.80319744893562 0.734504522625736 0.999999999989978 GO:0033293 monocarboxylic acid binding 6/1698 79/18639 0.0759493670886076 0.833698617882542 0.73692180733835 0.999999999989978 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/1698 54/18639 0.0740740740740741 0.813113466823714 0.737119338274193 0.999999999989978 GO:0004705 JUN kinase activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0005347 ATP transmembrane transporter activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0008195 phosphatidate phosphatase activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0008331 high voltage-gated calcium channel activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0015386 potassium:proton antiporter activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0019763 immunoglobulin receptor activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0031404 chloride ion binding 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0043176 amine binding 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0098821 BMP receptor activity 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:1990825 sequence-specific mRNA binding 1/1698 14/18639 0.0714285714285714 0.784073700151439 0.737567601935711 0.999999999989978 GO:0016866 intramolecular transferase activity 2/1698 28/18639 0.0714285714285714 0.784073700151439 0.737815530223212 0.999999999989978 GO:0046625 sphingolipid binding 2/1698 28/18639 0.0714285714285714 0.784073700151439 0.737815530223212 0.999999999989978 GO:0051119 sugar transmembrane transporter activity 2/1698 28/18639 0.0714285714285714 0.784073700151439 0.737815530223212 0.999999999989978 GO:0051959 dynein light intermediate chain binding 2/1698 28/18639 0.0714285714285714 0.784073700151439 0.737815530223212 0.999999999989978 GO:0042578 phosphoric ester hydrolase activity 30/1698 363/18639 0.0826446280991736 0.90719271091902 0.740071812173057 0.999999999989978 GO:0048306 calcium-dependent protein binding 6/1698 80/18639 0.075 0.823277385159011 0.747905881025305 0.999999999989978 GO:0004520 DNA endonuclease activity 3/1698 42/18639 0.0714285714285714 0.784073700151439 0.749459933296906 0.999999999989978 GO:0019894 kinesin binding 3/1698 42/18639 0.0714285714285714 0.784073700151439 0.749459933296906 0.999999999989978 GO:0051879 Hsp90 protein binding 3/1698 42/18639 0.0714285714285714 0.784073700151439 0.749459933296906 0.999999999989978 GO:0008374 O-acyltransferase activity 4/1698 55/18639 0.0727272727272727 0.798329585608738 0.750220240097313 0.999999999989978 GO:0005548 phospholipid transporter activity 5/1698 68/18639 0.0735294117647059 0.807134691332363 0.753748902572139 0.999999999989978 GO:0004629 phospholipase C activity 2/1698 29/18639 0.0689655172413793 0.757036676008286 0.75544900851327 0.999999999989978 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/1698 29/18639 0.0689655172413793 0.757036676008286 0.75544900851327 0.999999999989978 GO:0051861 glycolipid binding 2/1698 29/18639 0.0689655172413793 0.757036676008286 0.75544900851327 0.999999999989978 GO:0005506 iron ion binding 12/1698 154/18639 0.0779220779220779 0.855353127437933 0.755625763936035 0.999999999989978 GO:0016298 lipase activity 10/1698 130/18639 0.0769230769230769 0.844387061701549 0.756852377596119 0.999999999989978 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 10/1698 130/18639 0.0769230769230769 0.844387061701549 0.756852377596119 0.999999999989978 GO:0000774 adenyl-nucleotide exchange factor activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0004089 carbonate dehydratase activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0005523 tropomyosin binding 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0015929 hexosaminidase activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0031386 protein tag activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0034483 heparan sulfate sulfotransferase activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0051371 muscle alpha-actinin binding 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0120283 protein serine/threonine kinase binding 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0141047 molecular tag activity 1/1698 15/18639 0.0666666666666667 0.731802120141343 0.761492982441115 0.999999999989978 GO:0008375 acetylglucosaminyltransferase activity 3/1698 43/18639 0.0697674418604651 0.765839428054894 0.763731867948857 0.999999999989978 GO:0002039 p53 binding 5/1698 69/18639 0.072463768115942 0.795437087110155 0.765069786337139 0.999999999989978 GO:0005262 calcium channel activity 10/1698 131/18639 0.0763358778625954 0.837941358940469 0.765154093129687 0.999999999989978 GO:0031210 phosphatidylcholine binding 2/1698 30/18639 0.0666666666666667 0.731802120141343 0.772047854951711 0.999999999989978 GO:0098918 structural constituent of synapse 2/1698 30/18639 0.0666666666666667 0.731802120141343 0.772047854951711 0.999999999989978 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1698 70/18639 0.0714285714285714 0.784073700151439 0.775991716924795 0.999999999989978 GO:0019205 nucleobase-containing compound kinase activity 3/1698 44/18639 0.0681818181818182 0.748433986508191 0.77733567024146 0.999999999989978 GO:0030547 signaling receptor inhibitor activity 3/1698 44/18639 0.0681818181818182 0.748433986508191 0.77733567024146 0.999999999989978 GO:0005496 steroid binding 8/1698 108/18639 0.0740740740740741 0.813113466823714 0.778445265687775 0.999999999989978 GO:0030165 PDZ domain binding 6/1698 83/18639 0.072289156626506 0.793520371237601 0.778850352047726 0.999999999989978 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0004707 MAP kinase activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0005024 transforming growth factor beta receptor activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0005149 interleukin-1 receptor binding 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0005159 insulin-like growth factor receptor binding 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0015385 sodium:proton antiporter activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0017070 U6 snRNA binding 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0022858 alanine transmembrane transporter activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0070411 I-SMAD binding 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0140327 flippase activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0140328 floppase activity 1/1698 16/18639 0.0625 0.686064487632509 0.783238306529119 0.999999999989978 GO:0017147 Wnt-protein binding 2/1698 31/18639 0.0645161290322581 0.708195600136783 0.787654112758743 0.999999999989978 GO:0072349 modified amino acid transmembrane transporter activity 2/1698 31/18639 0.0645161290322581 0.708195600136783 0.787654112758743 0.999999999989978 GO:0008009 chemokine activity 3/1698 45/18639 0.0666666666666667 0.731802120141343 0.790288188692117 0.999999999989978 GO:0015085 calcium ion transmembrane transporter activity 11/1698 147/18639 0.0748299319727891 0.821410543015793 0.794079492292913 0.999999999989978 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 21/1698 268/18639 0.0783582089552239 0.860140551658668 0.79641171625139 0.999999999989978 GO:0001786 phosphatidylserine binding 4/1698 59/18639 0.0677966101694915 0.74420554590645 0.797627985512019 0.999999999989978 GO:0036002 pre-mRNA binding 4/1698 59/18639 0.0677966101694915 0.74420554590645 0.797627985512019 0.999999999989978 GO:0045309 protein phosphorylated amino acid binding 4/1698 59/18639 0.0677966101694915 0.74420554590645 0.797627985512019 0.999999999989978 GO:0015106 bicarbonate transmembrane transporter activity 2/1698 32/18639 0.0625 0.686064487632509 0.802310755050604 0.999999999989978 GO:0042910 xenobiotic transmembrane transporter activity 2/1698 32/18639 0.0625 0.686064487632509 0.802310755050604 0.999999999989978 GO:0047498 calcium-dependent phospholipase A2 activity 2/1698 32/18639 0.0625 0.686064487632509 0.802310755050604 0.999999999989978 GO:0071813 lipoprotein particle binding 2/1698 32/18639 0.0625 0.686064487632509 0.802310755050604 0.999999999989978 GO:0071814 protein-lipid complex binding 2/1698 32/18639 0.0625 0.686064487632509 0.802310755050604 0.999999999989978 GO:0120015 sterol transfer activity 2/1698 32/18639 0.0625 0.686064487632509 0.802310755050604 0.999999999989978 GO:0004180 carboxypeptidase activity 3/1698 46/18639 0.0652173913043478 0.71589337839914 0.802607500771276 0.999999999989978 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0008429 phosphatidylethanolamine binding 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0015278 intracellularly gated calcium channel activity 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0016805 dipeptidase activity 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0017110 nucleoside diphosphate phosphatase activity 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0030169 low-density lipoprotein particle binding 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0038191 neuropilin binding 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0045236 CXCR chemokine receptor binding 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0070402 NADPH binding 1/1698 17/18639 0.0588235294117647 0.645707753065891 0.803002112334497 0.999999999989978 GO:0061630 ubiquitin protein ligase activity 28/1698 353/18639 0.0793201133144476 0.870699406400464 0.806274934344077 0.999999999989978 GO:0008083 growth factor activity 12/1698 162/18639 0.0740740740740741 0.813113466823714 0.812448660745034 0.999999999989978 GO:0031406 carboxylic acid binding 14/1698 187/18639 0.0748663101604278 0.821809867538406 0.815302866926364 0.999999999989978 GO:0008081 phosphoric diester hydrolase activity 6/1698 87/18639 0.0689655172413793 0.757036676008286 0.81553183575645 0.999999999989978 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1698 33/18639 0.0606060606060606 0.665274654673948 0.816061166861499 0.999999999989978 GO:0019239 deaminase activity 2/1698 33/18639 0.0606060606060606 0.665274654673948 0.816061166861499 0.999999999989978 GO:0004721 phosphoprotein phosphatase activity 13/1698 175/18639 0.0742857142857143 0.815436648157496 0.816840800435548 0.999999999989978 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0004970 glutamate-gated receptor activity 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0008308 voltage-gated monoatomic anion channel activity 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0015280 ligand-gated sodium channel activity 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0017075 syntaxin-1 binding 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0017128 phospholipid scramblase activity 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0031690 adrenergic receptor binding 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0032393 MHC class I receptor activity 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0050811 GABA receptor binding 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:1901611 phosphatidylglycerol binding 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:1990381 ubiquitin-specific protease binding 1/1698 18/18639 0.0555555555555556 0.609835100117786 0.820964866778489 0.999999999989978 GO:0004252 serine-type endopeptidase activity 13/1698 176/18639 0.0738636363636364 0.810803485383874 0.822878821582235 0.999999999989978 GO:0046982 protein heterodimerization activity 29/1698 369/18639 0.0785907859078591 0.862693556264185 0.824418199076622 0.999999999989978 GO:0003725 double-stranded RNA binding 5/1698 75/18639 0.0666666666666667 0.731802120141343 0.824808522976361 0.999999999989978 GO:0043177 organic acid binding 14/1698 189/18639 0.0740740740740741 0.813113466823714 0.826935910698831 0.999999999989978 GO:0061134 peptidase regulator activity 17/1698 226/18639 0.0752212389380531 0.825705932017887 0.828683955614297 0.999999999989978 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1698 34/18639 0.0588235294117647 0.645707753065891 0.828948713726142 0.999999999989978 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/1698 89/18639 0.0674157303370786 0.740024615873268 0.831987295754319 0.999999999989978 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/1698 89/18639 0.0674157303370786 0.740024615873268 0.831987295754319 0.999999999989978 GO:0003774 cytoskeletal motor activity 11/1698 153/18639 0.0718954248366013 0.789198364858311 0.833842058827888 0.999999999989978 GO:0060590 ATPase regulator activity 3/1698 49/18639 0.0612244897959184 0.672063171558376 0.835960338853102 0.999999999989978 GO:0008574 plus-end-directed microtubule motor activity 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:0015245 fatty acid transmembrane transporter activity 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:0022821 solute:potassium antiporter activity 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:0042577 lipid phosphatase activity 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:0046624 sphingolipid transporter activity 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:0097001 ceramide binding 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:1990380 K48-linked deubiquitinase activity 1/1698 19/18639 0.0526315789473684 0.57773851590106 0.83729060955332 0.999999999989978 GO:1901682 sulfur compound transmembrane transporter activity 4/1698 63/18639 0.0634920634920635 0.696954400134612 0.837492303579517 0.999999999989978 GO:0140793 histone H2AXY142 phosphatase activity 6/1698 90/18639 0.0666666666666667 0.731802120141343 0.839762512971131 0.999999999989978 GO:0005154 epidermal growth factor receptor binding 2/1698 35/18639 0.0571428571428571 0.627258960121151 0.841016385365021 0.999999999989978 GO:0001217 DNA-binding transcription repressor activity 21/1698 278/18639 0.0755395683453237 0.829200244045047 0.845035255781249 0.999999999989978 GO:0072341 modified amino acid binding 6/1698 91/18639 0.0659340659340659 0.723760338601328 0.847244137346724 0.999999999989978 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 13/1698 181/18639 0.0718232044198895 0.788405599047303 0.850853157884213 0.999999999989978 GO:0001614 purinergic nucleotide receptor activity 1/1698 20/18639 0.05 0.548851590106007 0.8521284476295 0.999999999989978 GO:0001972 retinoic acid binding 1/1698 20/18639 0.05 0.548851590106007 0.8521284476295 0.999999999989978 GO:0015095 magnesium ion transmembrane transporter activity 1/1698 20/18639 0.05 0.548851590106007 0.8521284476295 0.999999999989978 GO:0016502 nucleotide receptor activity 1/1698 20/18639 0.05 0.548851590106007 0.8521284476295 0.999999999989978 GO:0004190 aspartic-type endopeptidase activity 2/1698 36/18639 0.0555555555555556 0.609835100117786 0.852306504381893 0.999999999989978 GO:0045505 dynein intermediate chain binding 2/1698 36/18639 0.0555555555555556 0.609835100117786 0.852306504381893 0.999999999989978 GO:0016597 amino acid binding 3/1698 51/18639 0.0588235294117647 0.645707753065891 0.85539528865885 0.999999999989978 GO:0030551 cyclic nucleotide binding 2/1698 37/18639 0.0540540540540541 0.593353070384873 0.862860491096566 0.999999999989978 GO:0070001 aspartic-type peptidase activity 2/1698 37/18639 0.0540540540540541 0.593353070384873 0.862860491096566 0.999999999989978 GO:0005080 protein kinase C binding 3/1698 52/18639 0.0576923076923077 0.633290296276162 0.864335366787129 0.999999999989978 GO:0001846 opsonin binding 1/1698 21/18639 0.0476190476190476 0.522715800100959 0.865613913869637 0.999999999989978 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1698 21/18639 0.0476190476190476 0.522715800100959 0.865613913869637 0.999999999989978 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/1698 21/18639 0.0476190476190476 0.522715800100959 0.865613913869637 0.999999999989978 GO:0009975 cyclase activity 1/1698 21/18639 0.0476190476190476 0.522715800100959 0.865613913869637 0.999999999989978 GO:0015125 bile acid transmembrane transporter activity 1/1698 21/18639 0.0476190476190476 0.522715800100959 0.865613913869637 0.999999999989978 GO:0051428 peptide hormone receptor binding 1/1698 21/18639 0.0476190476190476 0.522715800100959 0.865613913869637 0.999999999989978 GO:1904047 S-adenosyl-L-methionine binding 1/1698 21/18639 0.0476190476190476 0.522715800100959 0.865613913869637 0.999999999989978 GO:0042562 hormone binding 6/1698 94/18639 0.0638297872340425 0.700661604390647 0.867992489594548 0.999999999989978 GO:0005501 retinoid binding 2/1698 38/18639 0.0526315789473684 0.57773851590106 0.872718676712413 0.999999999989978 GO:0019840 isoprenoid binding 2/1698 38/18639 0.0526315789473684 0.57773851590106 0.872718676712413 0.999999999989978 GO:0005544 calcium-dependent phospholipid binding 3/1698 53/18639 0.0566037735849057 0.621341422761517 0.872785166740461 0.999999999989978 GO:0042277 peptide binding 18/1698 249/18639 0.072289156626506 0.793520371237601 0.877256440695087 0.999999999989978 GO:0008093 cytoskeletal anchor activity 1/1698 22/18639 0.0454545454545455 0.498955991005461 0.877870202098735 0.999999999989978 GO:0015377 chloride:monoatomic cation symporter activity 1/1698 22/18639 0.0454545454545455 0.498955991005461 0.877870202098735 0.999999999989978 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1698 22/18639 0.0454545454545455 0.498955991005461 0.877870202098735 0.999999999989978 GO:0005126 cytokine receptor binding 20/1698 275/18639 0.0727272727272727 0.798329585608738 0.882042162139404 0.999999999989978 GO:0004222 metalloendopeptidase activity 7/1698 110/18639 0.0636363636363636 0.698538387407645 0.883647867499056 0.999999999989978 GO:0046943 carboxylic acid transmembrane transporter activity 13/1698 188/18639 0.0691489361702128 0.759050071423201 0.884115252599739 0.999999999989978 GO:0098632 cell-cell adhesion mediator activity 3/1698 55/18639 0.0545454545454545 0.598747189206553 0.888296967446847 0.999999999989978 GO:0005342 organic acid transmembrane transporter activity 13/1698 189/18639 0.0687830687830688 0.755033933479163 0.88833872671742 0.999999999989978 GO:0003887 DNA-directed DNA polymerase activity 1/1698 23/18639 0.0434782608695652 0.477262252266093 0.889009289859188 0.999999999989978 GO:0016849 phosphorus-oxygen lyase activity 1/1698 23/18639 0.0434782608695652 0.477262252266093 0.889009289859188 0.999999999989978 GO:0031681 G-protein beta-subunit binding 1/1698 23/18639 0.0434782608695652 0.477262252266093 0.889009289859188 0.999999999989978 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1698 23/18639 0.0434782608695652 0.477262252266093 0.889009289859188 0.999999999989978 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1698 23/18639 0.0434782608695652 0.477262252266093 0.889009289859188 0.999999999989978 GO:0070577 lysine-acetylated histone binding 1/1698 23/18639 0.0434782608695652 0.477262252266093 0.889009289859188 0.999999999989978 GO:0071617 lysophospholipid acyltransferase activity 1/1698 23/18639 0.0434782608695652 0.477262252266093 0.889009289859188 0.999999999989978 GO:0015144 carbohydrate transmembrane transporter activity 2/1698 40/18639 0.05 0.548851590106007 0.890502687300648 0.999999999989978 GO:0140662 ATP-dependent protein folding chaperone 2/1698 40/18639 0.05 0.548851590106007 0.890502687300648 0.999999999989978 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1698 70/18639 0.0571428571428571 0.627258960121151 0.891392731573738 0.999999999989978 GO:0004725 protein tyrosine phosphatase activity 6/1698 98/18639 0.0612244897959184 0.672063171558376 0.891955728605972 0.999999999989978 GO:0005200 structural constituent of cytoskeleton 7/1698 112/18639 0.0625 0.686064487632509 0.89424219647908 0.999999999989978 GO:0005539 glycosaminoglycan binding 17/1698 242/18639 0.0702479338842975 0.771113804281167 0.897515522560258 0.999999999989978 GO:0042287 MHC protein binding 2/1698 41/18639 0.0487804878048781 0.53546496595708 0.898502593181413 0.999999999989978 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0004806 triacylglycerol lipase activity 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0030215 semaphorin receptor binding 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0070300 phosphatidic acid binding 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0140033 acetylation-dependent protein binding 1/1698 24/18639 0.0416666666666667 0.457376325088339 0.899132959058753 0.999999999989978 GO:0004713 protein tyrosine kinase activity 9/1698 140/18639 0.0642857142857143 0.705666330136295 0.900427860085939 0.999999999989978 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/1698 86/18639 0.0581395348837209 0.638199523379078 0.902088196233635 0.999999999989978 GO:0016209 antioxidant activity 5/1698 86/18639 0.0581395348837209 0.638199523379078 0.902088196233635 0.999999999989978 GO:0042379 chemokine receptor binding 4/1698 72/18639 0.0555555555555556 0.609835100117786 0.903594726146137 0.999999999989978 GO:0008307 structural constituent of muscle 2/1698 42/18639 0.0476190476190476 0.522715800100959 0.905954726175638 0.999999999989978 GO:0005516 calmodulin binding 14/1698 207/18639 0.0676328502415459 0.742407947969478 0.908120918208587 0.999999999989978 GO:0001848 complement binding 1/1698 25/18639 0.04 0.439081272084806 0.908333723792475 0.999999999989978 GO:0120020 cholesterol transfer activity 1/1698 25/18639 0.04 0.439081272084806 0.908333723792475 0.999999999989978 GO:0003779 actin binding 33/1698 443/18639 0.0744920993227991 0.817702143273058 0.908432042095416 0.999999999989978 GO:0017124 SH3 domain binding 7/1698 115/18639 0.0608695652173913 0.66816715317253 0.908597436231466 0.999999999989978 GO:0035401 histone H3Y41 kinase activity 7/1698 115/18639 0.0608695652173913 0.66816715317253 0.908597436231466 0.999999999989978 GO:0140801 histone H2AXY142 kinase activity 7/1698 115/18639 0.0608695652173913 0.66816715317253 0.908597436231466 0.999999999989978 GO:0015171 amino acid transmembrane transporter activity 6/1698 102/18639 0.0588235294117647 0.645707753065891 0.912109624190208 0.999999999989978 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1698 26/18639 0.0384615384615385 0.422193530850775 0.916695673776378 0.999999999989978 GO:0008066 glutamate receptor activity 1/1698 26/18639 0.0384615384615385 0.422193530850775 0.916695673776378 0.999999999989978 GO:0008143 poly(A) binding 1/1698 26/18639 0.0384615384615385 0.422193530850775 0.916695673776378 0.999999999989978 GO:0008157 protein phosphatase 1 binding 1/1698 26/18639 0.0384615384615385 0.422193530850775 0.916695673776378 0.999999999989978 GO:0061135 endopeptidase regulator activity 12/1698 184/18639 0.0652173913043478 0.71589337839914 0.917889656089438 0.999999999989978 GO:1901681 sulfur compound binding 19/1698 275/18639 0.0690909090909091 0.758413106328301 0.921324436467185 0.999999999989978 GO:0008201 heparin binding 11/1698 172/18639 0.063953488372093 0.702019475716986 0.921669797227286 0.999999999989978 GO:0015293 symporter activity 9/1698 146/18639 0.0616438356164384 0.67666634396631 0.923972175469405 0.999999999989978 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1698 27/18639 0.037037037037037 0.406556733411857 0.924295241064172 0.999999999989978 GO:0017022 myosin binding 4/1698 76/18639 0.0526315789473684 0.57773851590106 0.924411022347507 0.999999999989978 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/1698 45/18639 0.0444444444444444 0.487868080094228 0.925350269352426 0.999999999989978 GO:0140303 intramembrane lipid transporter activity 2/1698 45/18639 0.0444444444444444 0.487868080094228 0.925350269352426 0.999999999989978 GO:0005178 integrin binding 10/1698 161/18639 0.062111801242236 0.68180321752299 0.929127315870811 0.999999999989978 GO:0043178 alcohol binding 5/1698 92/18639 0.0543478260869565 0.596577815332616 0.930180544754858 0.999999999989978 GO:0045499 chemorepellent activity 1/1698 28/18639 0.0357142857142857 0.392036850075719 0.931201897021245 0.999999999989978 GO:0046875 ephrin receptor binding 1/1698 28/18639 0.0357142857142857 0.392036850075719 0.931201897021245 0.999999999989978 GO:0051393 alpha-actinin binding 1/1698 28/18639 0.0357142857142857 0.392036850075719 0.931201897021245 0.999999999989978 GO:0051082 unfolded protein binding 7/1698 121/18639 0.0578512396694215 0.635034897643314 0.932350682057186 0.999999999989978 GO:0005507 copper ion binding 3/1698 63/18639 0.0476190476190476 0.522715800100959 0.93472279089311 0.999999999989978 GO:0001784 phosphotyrosine residue binding 2/1698 47/18639 0.0425531914893617 0.467107736260432 0.936112456008055 0.999999999989978 GO:0003785 actin monomer binding 1/1698 29/18639 0.0344827586206897 0.378518338004143 0.93747878589653 0.999999999989978 GO:0008514 organic anion transmembrane transporter activity 18/1698 269/18639 0.0669144981412639 0.734522574119563 0.937892446983072 0.999999999989978 GO:0004867 serine-type endopeptidase inhibitor activity 5/1698 95/18639 0.0526315789473684 0.57773851590106 0.941329030076892 0.999999999989978 GO:0038024 cargo receptor activity 3/1698 65/18639 0.0461538461538462 0.50663223702093 0.943144644550315 0.999999999989978 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/1698 30/18639 0.0333333333333333 0.365901060070671 0.943183300756696 0.999999999989978 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/1698 30/18639 0.0333333333333333 0.365901060070671 0.943183300756696 0.999999999989978 GO:0048019 receptor antagonist activity 1/1698 30/18639 0.0333333333333333 0.365901060070671 0.943183300756696 0.999999999989978 GO:0004896 cytokine receptor activity 5/1698 96/18639 0.0520833333333333 0.571720406360424 0.944672424679168 0.999999999989978 GO:0015101 organic cation transmembrane transporter activity 4/1698 81/18639 0.0493827160493827 0.542075644549143 0.944701614473601 0.999999999989978 GO:0005004 GPI-linked ephrin receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0005008 hepatocyte growth factor receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0005009 insulin receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0005011 macrophage colony-stimulating factor receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0005020 stem cell factor receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0008288 boss receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0036332 placental growth factor receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0038062 protein tyrosine kinase collagen receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0060175 brain-derived neurotrophic factor receptor activity 2/1698 49/18639 0.0408163265306122 0.448042114372251 0.945391602014103 0.999999999989978 GO:0033218 amide binding 16/1698 247/18639 0.0647773279352227 0.711062788801305 0.946300355902833 0.999999999989978 GO:0005184 neuropeptide hormone activity 1/1698 31/18639 0.032258064516129 0.354097800068392 0.948367607023294 0.999999999989978 GO:0016411 acylglycerol O-acyltransferase activity 1/1698 31/18639 0.032258064516129 0.354097800068392 0.948367607023294 0.999999999989978 GO:0005006 epidermal growth factor receptor activity 2/1698 50/18639 0.04 0.439081272084806 0.94953525397717 0.999999999989978 GO:0005007 fibroblast growth factor receptor activity 2/1698 50/18639 0.04 0.439081272084806 0.94953525397717 0.999999999989978 GO:0005017 platelet-derived growth factor receptor activity 2/1698 50/18639 0.04 0.439081272084806 0.94953525397717 0.999999999989978 GO:0005019 platelet-derived growth factor beta-receptor activity 2/1698 50/18639 0.04 0.439081272084806 0.94953525397717 0.999999999989978 GO:0048020 CCR chemokine receptor binding 2/1698 50/18639 0.04 0.439081272084806 0.94953525397717 0.999999999989978 GO:0001540 amyloid-beta binding 4/1698 83/18639 0.0481927710843374 0.529013580825067 0.951320294790942 0.999999999989978 GO:0005254 chloride channel activity 4/1698 83/18639 0.0481927710843374 0.529013580825067 0.951320294790942 0.999999999989978 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1698 32/18639 0.03125 0.343032243816254 0.953079118377252 0.999999999989978 GO:0070717 poly-purine tract binding 1/1698 32/18639 0.03125 0.343032243816254 0.953079118377252 0.999999999989978 GO:0160041 neuropeptide activity 1/1698 32/18639 0.03125 0.343032243816254 0.953079118377252 0.999999999989978 GO:0005010 insulin-like growth factor receptor activity 2/1698 51/18639 0.0392156862745098 0.43047183537726 0.953377701541183 0.999999999989978 GO:0005021 vascular endothelial growth factor receptor activity 2/1698 51/18639 0.0392156862745098 0.43047183537726 0.953377701541183 0.999999999989978 GO:0005030 neurotrophin receptor activity 2/1698 51/18639 0.0392156862745098 0.43047183537726 0.953377701541183 0.999999999989978 GO:0003777 microtubule motor activity 3/1698 68/18639 0.0441176470588235 0.484280814799418 0.953903253156897 0.999999999989978 GO:0140311 protein sequestering activity 1/1698 33/18639 0.0303030303030303 0.332637327336974 0.957360929362119 0.999999999989978 GO:0015294 solute:monoatomic cation symporter activity 6/1698 116/18639 0.0517241379310345 0.567777507006214 0.959140825211614 0.999999999989978 GO:0005003 ephrin receptor activity 2/1698 53/18639 0.0377358490566038 0.414227615174345 0.960239560742752 0.999999999989978 GO:0005005 transmembrane-ephrin receptor activity 2/1698 53/18639 0.0377358490566038 0.414227615174345 0.960239560742752 0.999999999989978 GO:0017046 peptide hormone binding 2/1698 53/18639 0.0377358490566038 0.414227615174345 0.960239560742752 0.999999999989978 GO:0038064 collagen receptor activity 2/1698 53/18639 0.0377358490566038 0.414227615174345 0.960239560742752 0.999999999989978 GO:0015020 glucuronosyltransferase activity 1/1698 34/18639 0.0294117647058824 0.322853876532945 0.961252208623816 0.999999999989978 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1698 34/18639 0.0294117647058824 0.322853876532945 0.961252208623816 0.999999999989978 GO:0019825 oxygen binding 1/1698 34/18639 0.0294117647058824 0.322853876532945 0.961252208623816 0.999999999989978 GO:0090482 vitamin transmembrane transporter activity 1/1698 34/18639 0.0294117647058824 0.322853876532945 0.961252208623816 0.999999999989978 GO:0004866 endopeptidase inhibitor activity 9/1698 161/18639 0.0559006211180124 0.613622895770691 0.962981521055128 0.999999999989978 GO:0015485 cholesterol binding 2/1698 54/18639 0.037037037037037 0.406556733411857 0.963296255017803 0.999999999989978 GO:0016229 steroid dehydrogenase activity 1/1698 35/18639 0.0285714285714286 0.313629480060575 0.964788556366721 0.999999999989978 GO:0034061 DNA polymerase activity 1/1698 35/18639 0.0285714285714286 0.313629480060575 0.964788556366721 0.999999999989978 GO:0005319 lipid transporter activity 10/1698 178/18639 0.0561797752808989 0.61668717989439 0.967985343642146 0.999999999989978 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1698 36/18639 0.0277777777777778 0.304917550058893 0.968002329280574 0.999999999989978 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1698 36/18639 0.0277777777777778 0.304917550058893 0.968002329280574 0.999999999989978 GO:0170055 lipid transmembrane transporter activity 2/1698 56/18639 0.0357142857142857 0.392036850075719 0.968745921725352 0.999999999989978 GO:0022829 wide pore channel activity 1/1698 37/18639 0.027027027027027 0.296676535192436 0.970922935896796 0.999999999989978 GO:0023023 MHC protein complex binding 1/1698 37/18639 0.027027027027027 0.296676535192436 0.970922935896796 0.999999999989978 GO:0042805 actinin binding 1/1698 37/18639 0.027027027027027 0.296676535192436 0.970922935896796 0.999999999989978 GO:0004601 peroxidase activity 2/1698 57/18639 0.0350877192982456 0.385159010600707 0.971169634942747 0.999999999989978 GO:0051015 actin filament binding 12/1698 209/18639 0.0574162679425837 0.630260199164793 0.972416755140383 0.999999999989978 GO:0000146 microfilament motor activity 1/1698 38/18639 0.0263157894736842 0.28886925795053 0.973577105063942 0.999999999989978 GO:0098631 cell adhesion mediator activity 3/1698 76/18639 0.0394736842105263 0.433303886925795 0.974008701018158 0.999999999989978 GO:0030414 peptidase inhibitor activity 9/1698 169/18639 0.0532544378698225 0.584575658101073 0.975379353931965 0.999999999989978 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/1698 59/18639 0.0338983050847458 0.372102772953225 0.975484407166258 0.999999999989978 GO:0070888 E-box binding 2/1698 59/18639 0.0338983050847458 0.372102772953225 0.975484407166258 0.999999999989978 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/1698 60/18639 0.0333333333333333 0.365901060070671 0.977400608598882 0.999999999989978 GO:0019199 transmembrane receptor protein kinase activity 3/1698 78/18639 0.0384615384615385 0.422193530850775 0.977540364321727 0.999999999989978 GO:0071855 neuropeptide receptor binding 1/1698 40/18639 0.025 0.274425795053004 0.978181090056301 0.999999999989978 GO:0020037 heme binding 7/1698 142/18639 0.0492957746478873 0.541121286020007 0.97833145817679 0.999999999989978 GO:0015026 coreceptor activity 2/1698 61/18639 0.0327868852459016 0.359902682036726 0.979171401144156 0.999999999989978 GO:0019955 cytokine binding 7/1698 144/18639 0.0486111111111111 0.533605712603062 0.980677081023694 0.999999999989978 GO:0005245 voltage-gated calcium channel activity 1/1698 43/18639 0.0232558139534884 0.255279809351631 0.983628275296384 0.999999999989978 GO:0003730 mRNA 3'-UTR binding 15/1698 262/18639 0.0572519083969466 0.628456019205352 0.983704453350961 0.999999999989978 GO:0042605 peptide antigen binding 1/1698 45/18639 0.0222222222222222 0.243934040047114 0.986481651979465 0.999999999989978 GO:0005253 monoatomic anion channel activity 4/1698 103/18639 0.0388349514563107 0.426292497169714 0.987254430151861 0.999999999989978 GO:0016500 protein-hormone receptor activity 2/1698 67/18639 0.0298507462686567 0.327672591108064 0.987286641052282 0.999999999989978 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1698 46/18639 0.0217391304347826 0.238631126133047 0.987716144554428 0.999999999989978 GO:0046906 tetrapyrrole binding 7/1698 152/18639 0.0460526315789474 0.505521201413428 0.987895769516096 0.999999999989978 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 31/1698 484/18639 0.0640495867768595 0.70307435096224 0.988301614379494 0.999999999989978 GO:0015108 chloride transmembrane transporter activity 5/1698 121/18639 0.0413223140495868 0.45359635545951 0.98840317642116 0.999999999989978 GO:0140359 ABC-type transporter activity 1/1698 47/18639 0.0212765957446809 0.233553868130216 0.988837963870654 0.999999999989978 GO:0140375 immune receptor activity 7/1698 156/18639 0.0448717948717949 0.492559119325904 0.990471389172795 0.999999999989978 GO:0001216 DNA-binding transcription activator activity 31/1698 491/18639 0.0631364562118126 0.693050887710233 0.990914830768751 0.999999999989978 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/1698 73/18639 0.0273972602739726 0.30074059731836 0.992288661586519 0.999999999989978 GO:0005272 sodium channel activity 1/1698 51/18639 0.0196078431372549 0.21523591768863 0.992390522246153 0.999999999989978 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1698 53/18639 0.0188679245283019 0.207113807587172 0.993717297805866 0.999999999989978 GO:0001664 G protein-coupled receptor binding 16/1698 297/18639 0.0538720538720539 0.591355248599065 0.993850919091723 0.999999999989978 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/1698 54/18639 0.0185185185185185 0.203278366705929 0.994291279745263 0.999999999989978 GO:0008509 monoatomic anion transmembrane transporter activity 6/1698 149/18639 0.0402684563758389 0.442028126259871 0.994569980266535 0.999999999989978 GO:0042626 ATPase-coupled transmembrane transporter activity 3/1698 98/18639 0.0306122448979592 0.336031585779188 0.995040785843291 0.999999999989978 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1698 56/18639 0.0178571428571429 0.19601842503786 0.995286795454787 0.999999999989978 GO:0001618 virus receptor activity 2/1698 81/18639 0.0246913580246914 0.271037822274571 0.996073526393113 0.999999999989978 GO:0140272 exogenous protein binding 2/1698 82/18639 0.024390243902439 0.26773248297854 0.996393365508835 0.999999999989978 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1698 63/18639 0.0158730158730159 0.174238600033653 0.997590296613282 0.999999999989978 GO:0022835 transmitter-gated channel activity 1/1698 63/18639 0.0158730158730159 0.174238600033653 0.997590296613282 0.999999999989978 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1698 69/18639 0.0144927536231884 0.159087417422031 0.998644370594534 0.999999999989978 GO:0015103 inorganic anion transmembrane transporter activity 5/1698 165/18639 0.0303030303030303 0.332637327336974 0.999464714328489 0.999999999989978 GO:0015370 solute:sodium symporter activity 1/1698 79/18639 0.0126582278481013 0.13894976964709 0.999480504657801 0.999999999989978 GO:0004497 monooxygenase activity 2/1698 106/18639 0.0188679245283019 0.207113807587172 0.999545500980804 0.999999999989978 GO:0005179 hormone activity 3/1698 132/18639 0.0227272727272727 0.249477995502731 0.999672979385859 0.999999999989978 GO:0099094 ligand-gated monoatomic cation channel activity 3/1698 136/18639 0.0220588235294118 0.242140407399709 0.999764669232624 0.999999999989978 GO:0005125 cytokine activity 8/1698 234/18639 0.0341880341880342 0.375283138534022 0.999817519785744 0.999999999989978 GO:0015081 sodium ion transmembrane transporter activity 4/1698 164/18639 0.024390243902439 0.26773248297854 0.999868156035277 0.999999999989978 GO:0046873 metal ion transmembrane transporter activity 21/1698 450/18639 0.0466666666666667 0.51226148409894 0.99989166508636 0.999999999989978 GO:0030594 neurotransmitter receptor activity 1/1698 97/18639 0.0103092783505155 0.113165276310517 0.999907704412677 0.999999999989978 GO:0001653 peptide receptor activity 2/1698 128/18639 0.015625 0.171516121908127 0.999934706787265 0.999999999989978 GO:0005261 monoatomic cation channel activity 13/1698 341/18639 0.0381231671554252 0.418479218262645 0.999957732203356 0.999999999989978 GO:0015079 potassium ion transmembrane transporter activity 3/1698 160/18639 0.01875 0.205819346289753 0.999968303142947 0.999999999989978 GO:0022834 ligand-gated channel activity 4/1698 188/18639 0.0212765957446809 0.233553868130216 0.999980746106405 0.999999999989978 GO:0003823 antigen binding 3/1698 174/18639 0.0172413793103448 0.189259169002071 0.999990357875457 0.999999999989978 GO:0008528 G protein-coupled peptide receptor activity 1/1698 122/18639 0.00819672131147541 0.0899756705091815 0.999991649964105 0.999999999989978 GO:0005267 potassium channel activity 1/1698 124/18639 0.00806451612903226 0.0885244500170979 0.999993111176425 0.999999999989978 GO:0015276 ligand-gated monoatomic ion channel activity 3/1698 186/18639 0.0161290322580645 0.177048900034196 0.999996558336191 0.999999999989978 GO:0005216 monoatomic ion channel activity 17/1698 448/18639 0.0379464285714286 0.416539153205452 0.999996727998405 0.999999999989978 GO:0005244 voltage-gated monoatomic ion channel activity 2/1698 173/18639 0.0115606936416185 0.126902101758614 0.999998862485533 0.999999999989978 GO:0022843 voltage-gated monoatomic cation channel activity 1/1698 143/18639 0.00699300699300699 0.0767624601546863 0.999998893347841 0.999999999989978 GO:0022832 voltage-gated channel activity 2/1698 175/18639 0.0114285714285714 0.12545179202423 0.999999051703217 0.999999999989978 GO:0022836 gated channel activity 6/1698 318/18639 0.0188679245283019 0.207113807587172 0.999999983306438 0.999999999989978 GO:0045182 translation regulator activity 6/1698 356/18639 0.0168539325842697 0.185006153968317 0.999999999276949 0.999999999989978 GO:0030371 translation repressor activity 3/1698 329/18639 0.00911854103343465 0.10009451491295 0.999999999989978 0.999999999989978