ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0005096	GTPase activator activity	18/321	271/18639	0.0664206642066421	3.85674380108287	1.17887093022045e-06	0.000320901784517334
GO:0030695	GTPase regulator activity	25/321	489/18639	0.0511247443762781	2.96857978326931	1.38493930259435e-06	0.000320901784517334
GO:0060589	nucleoside-triphosphatase regulator activity	25/321	490/18639	0.0510204081632653	2.962521457181	1.43687366201791e-06	0.000320901784517334
GO:0004721	phosphoprotein phosphatase activity	14/321	175/18639	0.08	4.64523364485981	2.14277229541603e-06	0.000358914359482186
GO:0140789	histone phosphatase activity	12/321	136/18639	0.0882352941176471	5.12341946124244	4.17784743165028e-06	0.000559831555841137
GO:0042578	phosphoric ester hydrolase activity	20/321	363/18639	0.0550964187327824	3.19919672511006	5.36259627904492e-06	0.000598823251160016
GO:0004674	protein serine/threonine kinase activity	21/321	433/18639	0.0484988452655889	2.81610584705705	2.16825676064846e-05	0.00207533147090638
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	10/321	128/18639	0.078125	4.53636098130841	7.52738764489669e-05	0.00620511148887577
GO:0016791	phosphatase activity	15/321	273/18639	0.0549450549450549	3.190407723118	8.33522438804207e-05	0.00620511148887577
GO:0019887	protein kinase regulator activity	14/321	255/18639	0.0549019607843137	3.18790544255085	0.000144312156743317	0.00832208879873605
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/321	89/18639	0.0898876404494382	5.2193636459099	0.000149320592603901	0.00832208879873605
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/321	89/18639	0.0898876404494382	5.2193636459099	0.000149320592603901	0.00832208879873605
GO:0140793	histone H2AXY142 phosphatase activity	8/321	90/18639	0.0888888888888889	5.1613707165109	0.000161473364751595	0.00832208879873605
GO:0106310	protein serine kinase activity	17/321	361/18639	0.0470914127423823	2.73438268568618	0.000187062262830799	0.00895226543547397
GO:0004725	protein tyrosine phosphatase activity	8/321	98/18639	0.0816326530612245	4.74003433148961	0.000291131557646399	0.0125359506564118
GO:0141003	histone H2AX kinase activity	16/321	354/18639	0.0451977401129944	2.62442578805639	0.00045216423290006	0.0125359506564118
GO:0019207	kinase regulator activity	14/321	287/18639	0.0487804878048781	2.83245953954867	0.000481701735170951	0.0125359506564118
GO:0033192	calmodulin-dependent protein phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:0140791	histone H2AXS140 phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:1990439	MAP kinase serine/threonine phosphatase activity	7/321	81/18639	0.0864197530864197	5.01799930771893	0.000491909686139725	0.0125359506564118
GO:0140996	histone H3 kinase activity	16/321	357/18639	0.0448179271708683	2.60237178983743	0.000495613178470341	0.0125359506564118
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	7/321	82/18639	0.0853658536585366	4.95680419421017	0.000530017235450696	0.0125359506564118
GO:0033549	MAP kinase phosphatase activity	7/321	82/18639	0.0853658536585366	4.95680419421017	0.000530017235450696	0.0125359506564118
GO:0035173	histone kinase activity	16/321	360/18639	0.0444444444444444	2.58068535825545	0.000542600849307377	0.0125359506564118
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	7/321	83/18639	0.0843373493975904	4.8970836617498	0.000570437557623461	0.0127397721202573
GO:0017018	myosin phosphatase activity	7/321	84/18639	0.0833333333333333	4.83878504672897	0.000613270235342625	0.0132545502477277
GO:0031625	ubiquitin protein ligase binding	14/321	302/18639	0.0463576158940397	2.69177446308102	0.000794000762003597	0.0166243909544503
GO:0017124	SH3 domain binding	8/321	115/18639	0.0695652173913043	4.03933360422592	0.00085090482725581	0.0172759464927695
GO:0003712	transcription coregulator activity	19/321	495/18639	0.0383838383838384	2.22877371849334	0.00101031435205761	0.0195273324682683
GO:0004715	non-membrane spanning protein tyrosine kinase activity	5/321	45/18639	0.111111111111111	6.45171339563863	0.00102008453192446	0.0195273324682683
GO:0030276	clathrin binding	5/321	46/18639	0.108695652173913	6.31145875660301	0.00112856313559247	0.0210038139124154
GO:0051020	GTPase binding	14/321	315/18639	0.0444444444444444	2.58068535825545	0.00118923037636702	0.0211792030523666
GO:0140857	histone H3T45 kinase activity	12/321	246/18639	0.0487804878048781	2.83245953954867	0.00120120853132825	0.0211792030523666
GO:0031267	small GTPase binding	13/321	283/18639	0.0459363957597173	2.66731613883293	0.00131381944482395	0.022570744308514
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	5/321	48/18639	0.104166666666667	6.04848130841121	0.00137083898530959	0.0229615530039356
GO:0044389	ubiquitin-like protein ligase binding	14/321	322/18639	0.0434782608695652	2.5245835026412	0.0014629798697318	0.0239072320175684
GO:0005178	integrin binding	9/321	161/18639	0.0559006211180124	3.2458930748244	0.00193380368045949	0.0308487729978062
GO:0004722	protein serine/threonine phosphatase activity	7/321	103/18639	0.0679611650485437	3.94619363034207	0.002033925606236	0.0312798792837388
GO:0045296	cadherin binding	14/321	334/18639	0.0419161676646707	2.43387990374391	0.00205420102758882	0.0312798792837388
GO:0005085	guanyl-nucleotide exchange factor activity	11/321	230/18639	0.0478260869565217	2.77704185290532	0.00221816115989562	0.0330259550473347
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	11/321	243/18639	0.0452674897119342	2.62847582785278	0.00338384881421092	0.0382886851177321
GO:0004676	3-phosphoinositide-dependent protein kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0004711	ribosomal protein S6 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0035175	histone H3S10 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0035979	histone H2AXS139 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0044022	histone H3S28 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0044023	histone H4S1 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0044024	histone H2AS1 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0044025	histone H2BS14 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0072354	histone H3T3 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0072371	histone H2AS121 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0072518	Rho-dependent protein serine/threonine kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0140823	histone H2BS36 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0140855	histone H3S57 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0140995	histone H2A kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0140997	histone H4 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0140998	histone H2B kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:1990244	histone H2AT120 kinase activity	11/321	245/18639	0.0448979591836735	2.60701888231928	0.00360027934689123	0.0382886851177321
GO:0004677	DNA-dependent protein kinase activity	11/321	246/18639	0.0447154471544715	2.59642124458628	0.00371257627868354	0.0388565350600121
GO:0035402	histone H3T11 kinase activity	11/321	247/18639	0.0445344129554656	2.58590941768512	0.00382765867755343	0.0388565350600121
GO:0035403	histone H3T6 kinase activity	11/321	247/18639	0.0445344129554656	2.58590941768512	0.00382765867755343	0.0388565350600121
GO:0004679	AMP-activated protein kinase activity	11/321	248/18639	0.0443548387096774	2.57548236358155	0.00394557529702527	0.0394557529702527
GO:0042169	SH2 domain binding	4/321	41/18639	0.0975609756097561	5.66491907909733	0.00529450098221792	0.052166406736559
GO:0019902	phosphatase binding	9/321	190/18639	0.0473684210526316	2.75046728971963	0.00578623510006782	0.0561851814064556
GO:0000287	magnesium ion binding	10/321	230/18639	0.0434782608695652	2.5245835026412	0.00672210066537534	0.0643401063685925
GO:0005158	insulin receptor binding	3/321	23/18639	0.130434782608696	7.57375050792361	0.00694199511056304	0.0645991211677394
GO:0070577	lysine-acetylated histone binding	3/321	23/18639	0.130434782608696	7.57375050792361	0.00694199511056304	0.0645991211677394
GO:0031072	heat shock protein binding	7/321	131/18639	0.0534351145038168	3.10273239637583	0.00763797342215823	0.0699827875344386
GO:0035035	histone acetyltransferase binding	3/321	24/18639	0.125	7.25817757009346	0.0078338941269894	0.0699827875344386
GO:0140033	acetylation-dependent protein binding	3/321	24/18639	0.125	7.25817757009346	0.0078338941269894	0.0699827875344386
GO:0043539	protein serine/threonine kinase activator activity	5/321	73/18639	0.0684931506849315	3.97708360005121	0.0084914117885212	0.0748584986619632
GO:0003714	transcription corepressor activity	9/321	204/18639	0.0441176470588235	2.56170973062122	0.00904401132789611	0.0786946440219532
GO:0045499	chemorepellent activity	3/321	28/18639	0.107142857142857	6.22129506008011	0.0120549735173359	0.101707863332827
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/321	10/18639	0.2	11.6130841121495	0.0121442224875017	0.101707863332827
GO:0051880	G-quadruplex DNA binding	2/321	10/18639	0.2	11.6130841121495	0.0121442224875017	0.101707863332827
GO:0019903	protein phosphatase binding	7/321	144/18639	0.0486111111111111	2.8226246105919	0.0124696204482552	0.103143774078161
GO:0003713	transcription coactivator activity	10/321	256/18639	0.0390625	2.26818049065421	0.0136079265676504	0.111186717077143
GO:0003925	G protein activity	4/321	54/18639	0.0740740740740741	4.30114226375909	0.0138970879332957	0.112181312232628
GO:0035401	histone H3Y41 kinase activity	6/321	115/18639	0.0521739130434783	3.02950020316944	0.0146488816857091	0.114332255021955
GO:0140801	histone H2AXY142 kinase activity	6/321	115/18639	0.0521739130434783	3.02950020316944	0.0146488816857091	0.114332255021955
GO:0032050	clathrin heavy chain binding	2/321	11/18639	0.181818181818182	10.5573491928632	0.01467548348043	0.114332255021955
GO:0004860	protein kinase inhibitor activity	5/321	84/18639	0.0595238095238095	3.45627503337784	0.0149944997865589	0.114618108537114
GO:1901981	phosphatidylinositol phosphate binding	8/321	185/18639	0.0432432432432432	2.51093710532963	0.0150543187332328	0.114618108537114
GO:0019208	phosphatase regulator activity	6/321	117/18639	0.0512820512820513	2.97771387491014	0.0158304357900991	0.119172943588387
GO:0008081	phosphoric diester hydrolase activity	5/321	87/18639	0.0574712643678161	3.33709313567515	0.0172210285923594	0.122801751294091
GO:0005078	MAP-kinase scaffold activity	2/321	12/18639	0.166666666666667	9.67757009345794	0.0174121886163264	0.122801751294091
GO:0005095	GTPase inhibitor activity	2/321	12/18639	0.166666666666667	9.67757009345794	0.0174121886163264	0.122801751294091
GO:0016273	arginine N-methyltransferase activity	2/321	12/18639	0.166666666666667	9.67757009345794	0.0174121886163264	0.122801751294091
GO:0016274	protein-arginine N-methyltransferase activity	2/321	12/18639	0.166666666666667	9.67757009345794	0.0174121886163264	0.122801751294091
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/321	12/18639	0.166666666666667	9.67757009345794	0.0174121886163264	0.122801751294091
GO:0003697	single-stranded DNA binding	6/321	121/18639	0.0495867768595041	2.87927705259906	0.0183881687674718	0.12833409452298
GO:0140375	immune receptor activity	7/321	156/18639	0.0448717948717949	2.60549964054637	0.0185991575666322	0.12846840793447
GO:0019210	kinase inhibitor activity	5/321	90/18639	0.0555555555555556	3.22585669781931	0.0196564003203019	0.134385594026554
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/321	13/18639	0.153846153846154	8.93314162473041	0.0203465564769387	0.137698917571202
GO:0005154	epidermal growth factor receptor binding	3/321	35/18639	0.0857142857142857	4.97703604806409	0.0220557091296466	0.144875736439836
GO:0010485	histone H4 acetyltransferase activity	3/321	35/18639	0.0857142857142857	4.97703604806409	0.0220557091296466	0.144875736439836
GO:0061631	ubiquitin conjugating enzyme activity	3/321	35/18639	0.0857142857142857	4.97703604806409	0.0220557091296466	0.144875736439836
GO:0008276	protein methyltransferase activity	5/321	95/18639	0.0526315789473684	3.05607476635514	0.0241975503420869	0.156697210316287
GO:0035591	signaling adaptor activity	6/321	129/18639	0.0465116279069767	2.70071723538361	0.0243231490640207	0.156697210316287
GO:0023023	MHC protein complex binding	3/321	37/18639	0.0810810810810811	4.70800707249305	0.0255364508220441	0.162469463450194
GO:0035091	phosphatidylinositol binding	10/321	284/18639	0.0352112676056338	2.04455706199816	0.0258597986861713	0.162469463450194
GO:0005543	phospholipid binding	15/321	497/18639	0.0301810865191147	1.75247748171271	0.0259466158047324	0.162469463450194
GO:0016247	channel regulator activity	7/321	168/18639	0.0416666666666667	2.41939252336449	0.0265861852387414	0.16310344861603
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/321	15/18639	0.133333333333333	7.74205607476635	0.02677817813099	0.16310344861603
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/321	15/18639	0.133333333333333	7.74205607476635	0.02677817813099	0.16310344861603
GO:0008170	N-methyltransferase activity	5/321	98/18639	0.0510204081632653	2.962521457181	0.0272211639610711	0.164307926611871
GO:0141108	transporter regulator activity	7/321	170/18639	0.0411764705882353	2.39092908191314	0.0281134769835361	0.16817883552651
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/321	16/18639	0.125	7.25817757009346	0.0302608784049641	0.174740036769157
GO:0005521	lamin binding	2/321	16/18639	0.125	7.25817757009346	0.0302608784049641	0.174740036769157
GO:0070411	I-SMAD binding	2/321	16/18639	0.125	7.25817757009346	0.0302608784049641	0.174740036769157
GO:0044325	transmembrane transporter binding	6/321	136/18639	0.0441176470588235	2.56170973062122	0.0304671603248925	0.174740036769157
GO:0140030	modification-dependent protein binding	7/321	173/18639	0.0404624277456647	2.34946788396089	0.0305143049283454	0.174740036769157
GO:0016279	protein-lysine N-methyltransferase activity	4/321	69/18639	0.0579710144927536	3.36611133685494	0.0311446000973844	0.176837983603793
GO:0016278	lysine N-methyltransferase activity	4/321	70/18639	0.0571428571428571	3.31802403204272	0.0325998849317071	0.181768991015931
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/321	41/18639	0.0731707317073171	4.248689309323	0.0333284060501664	0.181768991015931
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/321	41/18639	0.0731707317073171	4.248689309323	0.0333284060501664	0.181768991015931
GO:0030295	protein kinase activator activity	6/321	139/18639	0.0431654676258993	2.50642103139918	0.0333848147932573	0.181768991015931
GO:0031489	myosin V binding	2/321	17/18639	0.117647058823529	6.83122594832326	0.0339121251895393	0.181768991015931
GO:0038191	neuropilin binding	2/321	17/18639	0.117647058823529	6.83122594832326	0.0339121251895393	0.181768991015931
GO:1990226	histone methyltransferase binding	2/321	17/18639	0.117647058823529	6.83122594832326	0.0339121251895393	0.181768991015931
GO:0004713	protein tyrosine kinase activity	6/321	140/18639	0.0428571428571429	2.48851802403204	0.0343961993725583	0.182900425235032
GO:0004402	histone acetyltransferase activity	3/321	42/18639	0.0714285714285714	4.1475300400534	0.0354479879102592	0.185548061717763
GO:0035198	miRNA binding	3/321	42/18639	0.0714285714285714	4.1475300400534	0.0354479879102592	0.185548061717763
GO:0004712	protein serine/threonine/tyrosine kinase activity	3/321	43/18639	0.0697674418604651	4.05107585307542	0.0376354928122149	0.194253630034819
GO:0019888	protein phosphatase regulator activity	5/321	107/18639	0.0467289719626168	2.71333740938073	0.0376910028425768	0.194253630034819
GO:0043014	alpha-tubulin binding	3/321	44/18639	0.0681818181818182	3.9590059473237	0.0398904732010104	0.203470195032323
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	11/321	349/18639	0.0315186246418338	1.83014219532442	0.0400866652899501	0.203470195032323
GO:0042800	histone H3K4 methyltransferase activity	2/321	19/18639	0.105263157894737	6.11214953271028	0.0416932427013497	0.206922019332625
GO:0043395	heparan sulfate proteoglycan binding	2/321	19/18639	0.105263157894737	6.11214953271028	0.0416932427013497	0.206922019332625
GO:0050145	nucleoside monophosphate kinase activity	2/321	19/18639	0.105263157894737	6.11214953271028	0.0416932427013497	0.206922019332625
GO:0140303	intramembrane lipid transporter activity	3/321	45/18639	0.0666666666666667	3.87102803738318	0.0422124340057642	0.207958314587221
GO:0019209	kinase activator activity	6/321	148/18639	0.0405405405405405	2.35400353624653	0.0432009106112739	0.211274526347106
GO:0140297	DNA-binding transcription factor binding	14/321	488/18639	0.0286885245901639	1.66581124559522	0.0439989375654115	0.213618030208882
GO:0030291	protein serine/threonine kinase inhibitor activity	3/321	46/18639	0.0652173913043478	3.7868752539618	0.0446008351217101	0.214982442672991
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	8/321	229/18639	0.0349344978165939	2.02848630779904	0.045289352641461	0.216741901926992
GO:0140664	ATP-dependent DNA damage sensor activity	2/321	20/18639	0.1	5.80654205607477	0.0458100587179696	0.217679002418721
GO:0061733	protein-lysine-acetyltransferase activity	3/321	47/18639	0.0638297872340425	3.70630344004772	0.0470550938091436	0.220467922042841
GO:0140938	histone H3 methyltransferase activity	3/321	47/18639	0.0638297872340425	3.70630344004772	0.0470550938091436	0.220467922042841
GO:0140693	molecular condensate scaffold activity	3/321	48/18639	0.0625	3.62908878504673	0.0495745870116508	0.225256000659553
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/321	21/18639	0.0952380952380952	5.53004005340454	0.050069303411655	0.225256000659553
GO:0051010	microtubule plus-end binding	2/321	21/18639	0.0952380952380952	5.53004005340454	0.050069303411655	0.225256000659553
GO:0008970	phospholipase A1 activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0032931	histone H3K56 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0043992	histone H3K9 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0043993	histone H3K18 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0043994	histone H3K23 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0043999	histone H2AK5 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0044012	histone H2AK9 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0044014	histone H2BK5 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0044015	histone H2BK12 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0044016	histone H3K4 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0044017	histone H3K27 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0044018	histone H3K36 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0046972	histone H4K16 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0050321	tau-protein kinase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0070034	telomerase RNA binding	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0140908	histone H3K122 acetyltransferase activity	2/321	22/18639	0.0909090909090909	5.27867459643161	0.0544648837415636	0.225256000659553
GO:0051117	ATPase binding	4/321	84/18639	0.0476190476190476	2.76502002670227	0.057104155180408	0.233869142014466
GO:0004857	enzyme inhibitor activity	12/321	416/18639	0.0288461538461538	1.67496405463695	0.0573680655993479	0.233869142014466
GO:0016887	ATP hydrolysis activity	12/321	417/18639	0.0287769784172662	1.67094735426612	0.0582001905767371	0.233869142014466
GO:0099106	ion channel regulator activity	6/321	160/18639	0.0375	2.17745327102804	0.0588492176022551	0.233869142014466
GO:0044013	histone H2B acetyltransferase activity	2/321	23/18639	0.0869565217391304	5.04916700528241	0.0589908731349922	0.233869142014466
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/321	23/18639	0.0869565217391304	5.04916700528241	0.0589908731349922	0.233869142014466
GO:0140103	catalytic activity, acting on a glycoprotein	2/321	23/18639	0.0869565217391304	5.04916700528241	0.0589908731349922	0.233869142014466
GO:0005246	calcium channel regulator activity	3/321	53/18639	0.0566037735849057	3.28672191853289	0.0631262174858868	0.242271648212941
GO:0034212	protein N-acetyltransferase activity	3/321	53/18639	0.0566037735849057	3.28672191853289	0.0631262174858868	0.242271648212941
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/321	24/18639	0.0833333333333333	4.83878504672897	0.0636415075902652	0.242271648212941
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/321	24/18639	0.0833333333333333	4.83878504672897	0.0636415075902652	0.242271648212941
GO:0030215	semaphorin receptor binding	2/321	24/18639	0.0833333333333333	4.83878504672897	0.0636415075902652	0.242271648212941
GO:0043998	histone H2A acetyltransferase activity	2/321	24/18639	0.0833333333333333	4.83878504672897	0.0636415075902652	0.242271648212941
GO:0140612	DNA damage sensor activity	2/321	24/18639	0.0833333333333333	4.83878504672897	0.0636415075902652	0.242271648212941
GO:0042393	histone binding	8/321	247/18639	0.0323886639676113	1.88066139468009	0.0647154990478565	0.244968273231999
GO:0005516	calmodulin binding	7/321	207/18639	0.0338164251207729	1.96356494649871	0.0676135462281012	0.254500426813639
GO:0019211	phosphatase activator activity	2/321	25/18639	0.08	4.64523364485981	0.0684111818638131	0.255968778095509
GO:0042826	histone deacetylase binding	5/321	127/18639	0.0393700787401575	2.28604017955699	0.0687677314286441	0.255968778095509
GO:0051015	actin filament binding	7/321	209/18639	0.0334928229665072	1.94477485131691	0.0703875349828872	0.259685422833658
GO:0015631	tubulin binding	11/321	385/18639	0.0285714285714286	1.65901201602136	0.070541413366755	0.259685422833658
GO:0008094	ATP-dependent activity, acting on DNA	7/321	210/18639	0.0333333333333333	1.93551401869159	0.0717996779575171	0.262873137877248
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/321	26/18639	0.0769230769230769	4.46657081236521	0.073294445739713	0.265444749435717
GO:0004435	phosphatidylinositol phospholipase C activity	2/321	26/18639	0.0769230769230769	4.46657081236521	0.073294445739713	0.265444749435717
GO:0043178	alcohol binding	4/321	92/18639	0.0434782608695652	2.5245835026412	0.0745252159160395	0.268451046579282
GO:0061980	regulatory RNA binding	3/321	58/18639	0.0517241379310345	3.00338382210764	0.0781957806527715	0.278997980077636
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/321	27/18639	0.0740740740740741	4.30114226375909	0.0782860003799934	0.278997980077636
GO:0016410	N-acyltransferase activity	4/321	94/18639	0.0425531914893617	2.47086896003182	0.0792557308481969	0.280959469144402
GO:0036408	histone H3K14 acetyltransferase activity	2/321	28/18639	0.0714285714285714	4.1475300400534	0.0833806947540441	0.292487253849264
GO:0097718	disordered domain specific binding	2/321	28/18639	0.0714285714285714	4.1475300400534	0.0833806947540441	0.292487253849264
GO:0016407	acetyltransferase activity	4/321	96/18639	0.0416666666666667	2.41939252336449	0.0841322079735625	0.293586350741077
GO:0004629	phospholipase C activity	2/321	29/18639	0.0689655172413793	4.00451176281018	0.0885735221454985	0.301239897652203
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/321	29/18639	0.0689655172413793	4.00451176281018	0.0885735221454985	0.301239897652203
GO:0010484	histone H3 acetyltransferase activity	2/321	29/18639	0.0689655172413793	4.00451176281018	0.0885735221454985	0.301239897652203
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/321	29/18639	0.0689655172413793	4.00451176281018	0.0885735221454985	0.301239897652203
GO:0097472	cyclin-dependent protein kinase activity	2/321	29/18639	0.0689655172413793	4.00451176281018	0.0885735221454985	0.301239897652203
GO:0070851	growth factor receptor binding	5/321	139/18639	0.0359712230215827	2.08868419283265	0.0925956208599256	0.308264427511999
GO:0001968	fibronectin binding	2/321	30/18639	0.0666666666666667	3.87102803738318	0.0938596167349968	0.308264427511999
GO:0043995	histone H4K5 acetyltransferase activity	2/321	30/18639	0.0666666666666667	3.87102803738318	0.0938596167349968	0.308264427511999
GO:0043996	histone H4K8 acetyltransferase activity	2/321	30/18639	0.0666666666666667	3.87102803738318	0.0938596167349968	0.308264427511999
GO:0043997	histone H4K12 acetyltransferase activity	2/321	30/18639	0.0666666666666667	3.87102803738318	0.0938596167349968	0.308264427511999
GO:0051721	protein phosphatase 2A binding	2/321	30/18639	0.0666666666666667	3.87102803738318	0.0938596167349968	0.308264427511999
GO:0098918	structural constituent of synapse	2/321	30/18639	0.0666666666666667	3.87102803738318	0.0938596167349968	0.308264427511999
GO:0047499	calcium-independent phospholipase A2 activity	2/321	31/18639	0.0645161290322581	3.74615616520953	0.0992342502572594	0.322752173166814
GO:0070325	lipoprotein particle receptor binding	2/321	31/18639	0.0645161290322581	3.74615616520953	0.0992342502572594	0.322752173166814
GO:0019955	cytokine binding	5/321	144/18639	0.0347222222222222	2.01616043613707	0.103626596911621	0.33540975811974
GO:0047498	calcium-dependent phospholipase A2 activity	2/321	32/18639	0.0625	3.62908878504673	0.104692828730942	0.335582664900046
GO:0120015	sterol transfer activity	2/321	32/18639	0.0625	3.62908878504673	0.104692828730942	0.335582664900046
GO:0008235	metalloexopeptidase activity	3/321	66/18639	0.0454545454545455	2.6393372982158	0.105182626311955	0.335582664900046
GO:0042054	histone methyltransferase activity	3/321	67/18639	0.0447761194029851	2.59994420421258	0.108784099559118	0.345428183434166
GO:0071889	14-3-3 protein binding	2/321	33/18639	0.0606060606060606	3.51911639762107	0.110230889259765	0.348371206622843
GO:0030246	carbohydrate binding	8/321	280/18639	0.0285714285714286	1.65901201602136	0.112025451926664	0.350372054733347
GO:0030145	manganese ion binding	3/321	68/18639	0.0441176470588235	2.56170973062122	0.112432823533835	0.350372054733347
GO:1990841	promoter-specific chromatin binding	3/321	68/18639	0.0441176470588235	2.56170973062122	0.112432823533835	0.350372054733347
GO:0030332	cyclin binding	2/321	34/18639	0.0588235294117647	3.41561297416163	0.115844096903452	0.358551095222278
GO:0008080	N-acetyltransferase activity	3/321	69/18639	0.0434782608695652	2.5245835026412	0.116127742780947	0.358551095222278
GO:0004620	phospholipase activity	4/321	109/18639	0.036697247706422	2.13084112149533	0.119204542904084	0.366362585989615
GO:0097110	scaffold protein binding	3/321	70/18639	0.0428571428571429	2.48851802403204	0.11986779611748	0.366718828304619
GO:0004623	phospholipase A2 activity	2/321	35/18639	0.0571428571428571	3.31802403204272	0.121528241617016	0.370108735833639
GO:0005518	collagen binding	3/321	72/18639	0.0416666666666667	2.41939252336449	0.127479037538318	0.38647491018404
GO:0030280	structural constituent of skin epidermis	2/321	37/18639	0.0540540540540541	3.13867138166204	0.133093108653286	0.399876156043506
GO:0043394	proteoglycan binding	2/321	37/18639	0.0540540540540541	3.13867138166204	0.133093108653286	0.399876156043506
GO:0003725	double-stranded RNA binding	3/321	75/18639	0.04	2.32261682242991	0.139207652181004	0.41452945316121
GO:0019003	GDP binding	3/321	75/18639	0.04	2.32261682242991	0.139207652181004	0.41452945316121
GO:0098631	cell adhesion mediator activity	3/321	76/18639	0.0394736842105263	2.29205607476635	0.143196023226783	0.422083092053887
GO:1990782	protein tyrosine kinase binding	4/321	117/18639	0.0341880341880342	1.98514258327342	0.143445697568538	0.422083092053887
GO:0003779	actin binding	11/321	443/18639	0.0248306997742664	1.44180502521044	0.144671715635183	0.422083092053887
GO:0000217	DNA secondary structure binding	2/321	39/18639	0.0512820512820513	2.97771387491014	0.144894195779693	0.422083092053887
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/321	39/18639	0.0512820512820513	2.97771387491014	0.144894195779693	0.422083092053887
GO:0030331	nuclear estrogen receptor binding	2/321	40/18639	0.05	2.90327102803738	0.150874040573164	0.424075870489656
GO:0140662	ATP-dependent protein folding chaperone	2/321	40/18639	0.05	2.90327102803738	0.150874040573164	0.424075870489656
GO:0046332	SMAD binding	3/321	79/18639	0.0379746835443038	2.2050159706613	0.155382576789572	0.424075870489656
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/321	41/18639	0.0487804878048781	2.83245953954867	0.156902021830754	0.424075870489656
GO:0017080	sodium channel regulator activity	2/321	41/18639	0.0487804878048781	2.83245953954867	0.156902021830754	0.424075870489656
GO:0042287	MHC protein binding	2/321	41/18639	0.0487804878048781	2.83245953954867	0.156902021830754	0.424075870489656
GO:0005031	tumor necrosis factor receptor activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0005528	FK506 binding	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0015203	polyamine transmembrane transporter activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0015279	store-operated calcium channel activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0030957	Tat protein binding	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0031419	cobalamin binding	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0031434	mitogen-activated protein kinase kinase binding	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0031996	thioesterase binding	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0070513	death domain binding	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0140940	histone H2A methyltransferase activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0140999	histone H3K4 trimethyltransferase activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:1905394	retromer complex binding	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:1990259	histone H2AQ104 methyltransferase activity	1/321	10/18639	0.1	5.80654205607477	0.159503163228945	0.424075870489656
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	5/321	167/18639	0.029940119760479	1.73848564553137	0.161952017630891	0.428884789773506
GO:0001618	virus receptor activity	3/321	81/18639	0.037037037037037	2.15057113187954	0.163680756940645	0.431756327363118
GO:0140272	exogenous protein binding	3/321	82/18639	0.0365853658536585	2.1243446546615	0.167878788294348	0.438102837895917
GO:0048156	tau protein binding	2/321	43/18639	0.0465116279069767	2.70071723538361	0.169088832342123	0.438102837895917
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0001851	complement component C3b binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0002162	dystroglycan binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0003953	NAD+ nucleosidase activity	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0005114	type II transforming growth factor beta receptor binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0019864	IgG binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0034056	estrogen response element binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0045294	alpha-catenin binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0048185	activin binding	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0097493	structural molecule activity conferring elasticity	1/321	11/18639	0.0909090909090909	5.27867459643161	0.173985931203797	0.438102837895917
GO:0016248	channel inhibitor activity	2/321	44/18639	0.0454545454545455	2.6393372982158	0.175241135158367	0.438102837895917
GO:0019205	nucleobase-containing compound kinase activity	2/321	44/18639	0.0454545454545455	2.6393372982158	0.175241135158367	0.438102837895917
GO:0008009	chemokine activity	2/321	45/18639	0.0444444444444444	2.58068535825545	0.181428516607325	0.448550207110361
GO:0051539	4 iron, 4 sulfur cluster binding	2/321	45/18639	0.0444444444444444	2.58068535825545	0.181428516607325	0.448550207110361
GO:0141110	transporter inhibitor activity	2/321	45/18639	0.0444444444444444	2.58068535825545	0.181428516607325	0.448550207110361
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/321	86/18639	0.0348837209302326	2.02553792653771	0.184972524017946	0.448780563088186
GO:0016298	lipase activity	4/321	130/18639	0.0307692307692308	1.78662832494608	0.186464564882196	0.448780563088186
GO:0005025	transforming growth factor beta receptor activity, type I	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0005026	transforming growth factor beta receptor activity, type II	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0005527	macrolide binding	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0016361	activin receptor activity, type I	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0016362	activin receptor activity, type II	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0017002	activin receptor activity	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0036009	protein-glutamine N-methyltransferase activity	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0070679	inositol 1,4,5 trisphosphate binding	1/321	12/18639	0.0833333333333333	4.83878504672897	0.188219907802657	0.448780563088186
GO:0005319	lipid transporter activity	5/321	178/18639	0.0280898876404494	1.63105113934684	0.193669001505385	0.457431950703198
GO:0004197	cysteine-type endopeptidase activity	3/321	88/18639	0.0340909090909091	1.97950297366185	0.193685729286314	0.457431950703198
GO:0001784	phosphotyrosine residue binding	2/321	47/18639	0.0425531914893617	2.47086896003182	0.193896528357773	0.457431950703198
GO:0005126	cytokine receptor binding	7/321	275/18639	0.0254545454545455	1.47802888700085	0.197486890194	0.457703604763964
GO:0005035	death receptor activity	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0008035	high-density lipoprotein particle binding	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0008417	fucosyltransferase activity	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0031432	titin binding	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0031994	insulin-like growth factor I binding	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0035325	Toll-like receptor binding	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0046974	histone H3K9 methyltransferase activity	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0046975	histone H3K36 methyltransferase activity	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0070123	transforming growth factor beta receptor activity, type III	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0140333	glycerophospholipid flippase activity	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0140852	histone ubiquitin ligase activity	1/321	13/18639	0.0769230769230769	4.46657081236521	0.202209353746468	0.457703604763964
GO:0035254	glutamate receptor binding	2/321	49/18639	0.0408163265306122	2.3700171657448	0.206469809916522	0.460803077066522
GO:0060590	ATPase regulator activity	2/321	49/18639	0.0408163265306122	2.3700171657448	0.206469809916522	0.460803077066522
GO:0019838	growth factor binding	4/321	136/18639	0.0294117647058824	1.70780648708081	0.207583064222546	0.460803077066522
GO:0016922	nuclear receptor binding	4/321	137/18639	0.0291970802919708	1.6953407462992	0.211168670716645	0.460803077066522
GO:0008237	metallopeptidase activity	5/321	184/18639	0.0271739130434783	1.57786468915075	0.211823811068421	0.460803077066522
GO:0048020	CCR chemokine receptor binding	2/321	50/18639	0.04	2.32261682242991	0.21278911047492	0.460803077066522
GO:0051219	phosphoprotein binding	3/321	93/18639	0.032258064516129	1.87307808260476	0.215888135168525	0.460803077066522
GO:0005161	platelet-derived growth factor receptor binding	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0005545	1-phosphatidylinositol binding	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0008195	phosphatidate phosphatase activity	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0015386	potassium:proton antiporter activity	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0019763	immunoglobulin receptor activity	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0030983	mismatched DNA binding	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0042043	neurexin family protein binding	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0044548	S100 protein binding	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0061665	SUMO ligase activity	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0071933	Arp2/3 complex binding	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0098821	BMP receptor activity	1/321	14/18639	0.0714285714285714	4.1475300400534	0.215958457013266	0.460803077066522
GO:0030544	Hsp70 protein binding	2/321	51/18639	0.0392156862745098	2.27707531610775	0.219126719682138	0.466079054562009
GO:0140097	catalytic activity, acting on DNA	8/321	336/18639	0.0238095238095238	1.38251001335113	0.224296112968267	0.475564543318795
GO:0000774	adenyl-nucleotide exchange factor activity	1/321	15/18639	0.0666666666666667	3.87102803738318	0.229471334076286	0.475993169755763
GO:0004559	alpha-mannosidase activity	1/321	15/18639	0.0666666666666667	3.87102803738318	0.229471334076286	0.475993169755763
GO:0031386	protein tag activity	1/321	15/18639	0.0666666666666667	3.87102803738318	0.229471334076286	0.475993169755763
GO:0033130	acetylcholine receptor binding	1/321	15/18639	0.0666666666666667	3.87102803738318	0.229471334076286	0.475993169755763
GO:0120283	protein serine/threonine kinase binding	1/321	15/18639	0.0666666666666667	3.87102803738318	0.229471334076286	0.475993169755763
GO:0140776	protein-containing complex destabilizing activity	1/321	15/18639	0.0666666666666667	3.87102803738318	0.229471334076286	0.475993169755763
GO:0141047	molecular tag activity	1/321	15/18639	0.0666666666666667	3.87102803738318	0.229471334076286	0.475993169755763
GO:0005544	calcium-dependent phospholipid binding	2/321	53/18639	0.0377358490566038	2.19114794568859	0.231846962804799	0.479436620614862
GO:0015485	cholesterol binding	2/321	54/18639	0.037037037037037	2.15057113187954	0.238224844118982	0.482622732495837
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/321	54/18639	0.037037037037037	2.15057113187954	0.238224844118982	0.482622732495837
GO:0004708	MAP kinase kinase activity	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0005024	transforming growth factor beta receptor activity	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0015385	sodium:proton antiporter activity	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0015923	mannosidase activity	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0019841	retinol binding	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0030275	LRR domain binding	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0034450	ubiquitin-ubiquitin ligase activity	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0140327	flippase activity	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0140328	floppase activity	1/321	16/18639	0.0625	3.62908878504673	0.24275203112104	0.482622732495837
GO:0098632	cell-cell adhesion mediator activity	2/321	55/18639	0.0363636363636364	2.11146983857264	0.244611524922209	0.483450506483422
GO:0140313	molecular sequestering activity	2/321	55/18639	0.0363636363636364	2.11146983857264	0.244611524922209	0.483450506483422
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0008429	phosphatidylethanolamine binding	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0016805	dipeptidase activity	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0019198	transmembrane receptor protein phosphatase activity	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0030548	acetylcholine receptor regulator activity	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0032183	SUMO binding	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0046965	nuclear retinoid X receptor binding	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0051787	misfolded protein binding	1/321	17/18639	0.0588235294117647	3.41561297416163	0.255804525241759	0.493916518478324
GO:0008238	exopeptidase activity	3/321	102/18639	0.0294117647058824	1.70780648708081	0.257031888605923	0.494860245304507
GO:0000400	four-way junction DNA binding	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0008409	5'-3' exonuclease activity	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0017128	phospholipid scramblase activity	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0031690	adrenergic receptor binding	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0050811	GABA receptor binding	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0098641	cadherin binding involved in cell-cell adhesion	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0099602	neurotransmitter receptor regulator activity	1/321	18/18639	0.0555555555555556	3.22585669781931	0.268632725617518	0.503565604439273
GO:0031593	polyubiquitin modification-dependent protein binding	2/321	59/18639	0.0338983050847458	1.96831934104229	0.270203573952014	0.503565604439273
GO:0036002	pre-mRNA binding	2/321	59/18639	0.0338983050847458	1.96831934104229	0.270203573952014	0.503565604439273
GO:0045309	protein phosphorylated amino acid binding	2/321	59/18639	0.0338983050847458	1.96831934104229	0.270203573952014	0.503565604439273
GO:0061775	cohesin loader activity	4/321	153/18639	0.0261437908496732	1.5180502107385	0.270572563579311	0.503565604439273
GO:0000149	SNARE binding	3/321	106/18639	0.0283018867924528	1.64336095926644	0.27565894097216	0.510318498950733
GO:0008168	methyltransferase activity	5/321	204/18639	0.0245098039215686	1.42317207256734	0.27572432331368	0.510318498950733
GO:0005520	insulin-like growth factor binding	1/321	19/18639	0.0526315789473684	3.05607476635514	0.281240474668417	0.513436288904194
GO:0016918	retinal binding	1/321	19/18639	0.0526315789473684	3.05607476635514	0.281240474668417	0.513436288904194
GO:0022821	solute:potassium antiporter activity	1/321	19/18639	0.0526315789473684	3.05607476635514	0.281240474668417	0.513436288904194
GO:0030506	ankyrin binding	1/321	19/18639	0.0526315789473684	3.05607476635514	0.281240474668417	0.513436288904194
GO:0042577	lipid phosphatase activity	1/321	19/18639	0.0526315789473684	3.05607476635514	0.281240474668417	0.513436288904194
GO:0140658	ATP-dependent chromatin remodeler activity	4/321	158/18639	0.0253164556962025	1.47001064710754	0.289731599469261	0.527430514769628
GO:0000339	RNA cap binding	1/321	20/18639	0.05	2.90327102803738	0.293631549192125	0.527430514769628
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/321	20/18639	0.05	2.90327102803738	0.293631549192125	0.527430514769628
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/321	20/18639	0.05	2.90327102803738	0.293631549192125	0.527430514769628
GO:0042288	MHC class I protein binding	1/321	20/18639	0.05	2.90327102803738	0.293631549192125	0.527430514769628
GO:0140939	histone H4 methyltransferase activity	1/321	20/18639	0.05	2.90327102803738	0.293631549192125	0.527430514769628
GO:0004222	metalloendopeptidase activity	3/321	110/18639	0.0272727272727273	1.58360237892948	0.294416436602747	0.527430514769628
GO:1902936	phosphatidylinositol bisphosphate binding	3/321	111/18639	0.027027027027027	1.56933569083102	0.299120015482806	0.534427760995948
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/321	21/18639	0.0476190476190476	2.76502002670227	0.305809661481148	0.540613385731845
GO:0001846	opsonin binding	1/321	21/18639	0.0476190476190476	2.76502002670227	0.305809661481148	0.540613385731845
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/321	21/18639	0.0476190476190476	2.76502002670227	0.305809661481148	0.540613385731845
GO:0072542	protein phosphatase activator activity	1/321	21/18639	0.0476190476190476	2.76502002670227	0.305809661481148	0.540613385731845
GO:0120013	lipid transfer activity	2/321	65/18639	0.0307692307692308	1.78662832494608	0.308515504038379	0.543961546593984
GO:0016741	transferase activity, transferring one-carbon groups	5/321	215/18639	0.0232558139534884	1.35035861769181	0.312441424819577	0.549437676191907
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/321	22/18639	0.0454545454545455	2.6393372982158	0.317778460421129	0.551912689752106
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/321	22/18639	0.0454545454545455	2.6393372982158	0.317778460421129	0.551912689752106
GO:0034062	5'-3' RNA polymerase activity	1/321	22/18639	0.0454545454545455	2.6393372982158	0.317778460421129	0.551912689752106
GO:0097747	RNA polymerase activity	1/321	22/18639	0.0454545454545455	2.6393372982158	0.317778460421129	0.551912689752106
GO:0001221	transcription coregulator binding	3/321	115/18639	0.0260869565217391	1.51475010158472	0.31796760931987	0.551912689752106
GO:0016500	protein-hormone receptor activity	2/321	67/18639	0.0298507462686567	1.73329613614172	0.321210750526044	0.55475584628702
GO:0005525	GTP binding	8/321	378/18639	0.0211640211640212	1.22889778964545	0.327284976033586	0.55475584628702
GO:0005548	phospholipid transporter activity	2/321	68/18639	0.0294117647058824	1.70780648708081	0.327537354374293	0.55475584628702
GO:0032934	sterol binding	2/321	68/18639	0.0294117647058824	1.70780648708081	0.327537354374293	0.55475584628702
GO:0005201	extracellular matrix structural constituent	4/321	168/18639	0.0238095238095238	1.38251001335113	0.328533275127872	0.55475584628702
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/321	23/18639	0.0434782608695652	2.5245835026412	0.329541532570498	0.55475584628702
GO:0017134	fibroblast growth factor binding	1/321	23/18639	0.0434782608695652	2.5245835026412	0.329541532570498	0.55475584628702
GO:0042171	lysophosphatidic acid acyltransferase activity	1/321	23/18639	0.0434782608695652	2.5245835026412	0.329541532570498	0.55475584628702
GO:0043274	phospholipase binding	1/321	23/18639	0.0434782608695652	2.5245835026412	0.329541532570498	0.55475584628702
GO:0071617	lysophospholipid acyltransferase activity	1/321	23/18639	0.0434782608695652	2.5245835026412	0.329541532570498	0.55475584628702
GO:0099186	structural constituent of postsynapse	1/321	23/18639	0.0434782608695652	2.5245835026412	0.329541532570498	0.55475584628702
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/321	23/18639	0.0434782608695652	2.5245835026412	0.329541532570498	0.55475584628702
GO:0008017	microtubule binding	6/321	276/18639	0.0217391304347826	1.2622917513206	0.340103662630207	0.565689629105481
GO:0004622	lysophospholipase activity	1/321	24/18639	0.0416666666666667	2.41939252336449	0.341102403221812	0.565689629105481
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/321	24/18639	0.0416666666666667	2.41939252336449	0.341102403221812	0.565689629105481
GO:0030552	cAMP binding	1/321	24/18639	0.0416666666666667	2.41939252336449	0.341102403221812	0.565689629105481
GO:0048027	mRNA 5'-UTR binding	1/321	24/18639	0.0416666666666667	2.41939252336449	0.341102403221812	0.565689629105481
GO:0050431	transforming growth factor beta binding	1/321	24/18639	0.0416666666666667	2.41939252336449	0.341102403221812	0.565689629105481
GO:0003924	GTPase activity	7/321	331/18639	0.0211480362537764	1.22796961910947	0.344824859204482	0.57045100164692
GO:0140299	molecular sensor activity	2/321	71/18639	0.028169014084507	1.63564564959853	0.34641669111848	0.570749457186132
GO:0001848	complement binding	1/321	25/18639	0.04	2.32261682242991	0.352464537445063	0.570749457186132
GO:0004709	MAP kinase kinase kinase activity	1/321	25/18639	0.04	2.32261682242991	0.352464537445063	0.570749457186132
GO:0015662	P-type ion transporter activity	1/321	25/18639	0.04	2.32261682242991	0.352464537445063	0.570749457186132
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/321	25/18639	0.04	2.32261682242991	0.352464537445063	0.570749457186132
GO:0042974	nuclear retinoic acid receptor binding	1/321	25/18639	0.04	2.32261682242991	0.352464537445063	0.570749457186132
GO:0120020	cholesterol transfer activity	1/321	25/18639	0.04	2.32261682242991	0.352464537445063	0.570749457186132
GO:0140358	P-type transmembrane transporter activity	1/321	25/18639	0.04	2.32261682242991	0.352464537445063	0.570749457186132
GO:0042379	chemokine receptor binding	2/321	72/18639	0.0277777777777778	1.61292834890966	0.352672052649342	0.570749457186132
GO:0005160	transforming growth factor beta receptor binding	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0008157	protein phosphatase 1 binding	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0019865	immunoglobulin binding	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0030247	polysaccharide binding	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0030507	spectrin binding	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0050750	low-density lipoprotein particle receptor binding	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0051139	metal cation:proton antiporter activity	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0070006	metalloaminopeptidase activity	1/321	26/18639	0.0384615384615385	2.2332854061826	0.363631341113277	0.575964535569492
GO:0035064	methylated histone binding	2/321	74/18639	0.027027027027027	1.56933569083102	0.365118990398396	0.576956895205013
GO:0044183	protein folding chaperone	2/321	75/18639	0.0266666666666667	1.54841121495327	0.37130834213038	0.585049250536541
GO:0001671	ATPase activator activity	1/321	27/18639	0.037037037037037	2.15057113187954	0.37460616191071	0.585049250536541
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/321	27/18639	0.037037037037037	2.15057113187954	0.37460616191071	0.585049250536541
GO:0016405	CoA-ligase activity	1/321	27/18639	0.037037037037037	2.15057113187954	0.37460616191071	0.585049250536541
GO:0035255	ionotropic glutamate receptor binding	1/321	27/18639	0.037037037037037	2.15057113187954	0.37460616191071	0.585049250536541
GO:0017022	myosin binding	2/321	76/18639	0.0263157894736842	1.52803738317757	0.377473539938585	0.585433499441787
GO:0051536	iron-sulfur cluster binding	2/321	76/18639	0.0263157894736842	1.52803738317757	0.377473539938585	0.585433499441787
GO:0140034	methylation-dependent protein binding	2/321	76/18639	0.0263157894736842	1.52803738317757	0.377473539938585	0.585433499441787
GO:0051540	metal cluster binding	2/321	77/18639	0.025974025974026	1.5081927418376	0.383613580542496	0.588184133296188
GO:0019001	guanyl nucleotide binding	8/321	400/18639	0.02	1.16130841121495	0.384354885886068	0.588184133296188
GO:0032561	guanyl ribonucleotide binding	8/321	400/18639	0.02	1.16130841121495	0.384354885886068	0.588184133296188
GO:0019789	SUMO transferase activity	1/321	28/18639	0.0357142857142857	2.0737650200267	0.38539229032392	0.588184133296188
GO:0046875	ephrin receptor binding	1/321	28/18639	0.0357142857142857	2.0737650200267	0.38539229032392	0.588184133296188
GO:0051959	dynein light intermediate chain binding	1/321	28/18639	0.0357142857142857	2.0737650200267	0.38539229032392	0.588184133296188
GO:0141052	histone H3 demethylase activity	1/321	28/18639	0.0357142857142857	2.0737650200267	0.38539229032392	0.588184133296188
GO:0019199	transmembrane receptor protein kinase activity	2/321	78/18639	0.0256410256410256	1.48885693745507	0.389727502148579	0.593448696453518
GO:0004181	metallocarboxypeptidase activity	1/321	29/18639	0.0344827586206897	2.00225588140509	0.395992960616007	0.596214120478032
GO:0035250	UDP-galactosyltransferase activity	1/321	29/18639	0.0344827586206897	2.00225588140509	0.395992960616007	0.596214120478032
GO:0043236	laminin binding	1/321	29/18639	0.0344827586206897	2.00225588140509	0.395992960616007	0.596214120478032
GO:0051861	glycolipid binding	1/321	29/18639	0.0344827586206897	2.00225588140509	0.395992960616007	0.596214120478032
GO:0106222	lncRNA binding	1/321	29/18639	0.0344827586206897	2.00225588140509	0.395992960616007	0.596214120478032
GO:0048306	calcium-dependent protein binding	2/321	80/18639	0.025	1.45163551401869	0.401873341912948	0.603589454508779
GO:0008234	cysteine-type peptidase activity	4/321	187/18639	0.0213903743315508	1.24204108151332	0.402693262933469	0.603589454508779
GO:0031210	phosphatidylcholine binding	1/321	30/18639	0.0333333333333333	1.93551401869159	0.406411351784317	0.603759657861403
GO:0031624	ubiquitin conjugating enzyme binding	1/321	30/18639	0.0333333333333333	1.93551401869159	0.406411351784317	0.603759657861403
GO:0032452	histone demethylase activity	1/321	30/18639	0.0333333333333333	1.93551401869159	0.406411351784317	0.603759657861403
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/321	30/18639	0.0333333333333333	1.93551401869159	0.406411351784317	0.603759657861403
GO:0030971	receptor tyrosine kinase binding	2/321	81/18639	0.0246913580246914	1.4337140879197	0.407903533937564	0.604635769332229
GO:0002020	protease binding	3/321	136/18639	0.0220588235294118	1.28085486531061	0.416213494915333	0.609510686236384
GO:0016779	nucleotidyltransferase activity	3/321	136/18639	0.0220588235294118	1.28085486531061	0.416213494915333	0.609510686236384
GO:0005164	tumor necrosis factor receptor binding	1/321	31/18639	0.032258064516129	1.87307808260476	0.416650588501886	0.609510686236384
GO:0016411	acylglycerol O-acyltransferase activity	1/321	31/18639	0.032258064516129	1.87307808260476	0.416650588501886	0.609510686236384
GO:0016878	acid-thiol ligase activity	1/321	31/18639	0.032258064516129	1.87307808260476	0.416650588501886	0.609510686236384
GO:0140457	protein demethylase activity	1/321	31/18639	0.032258064516129	1.87307808260476	0.416650588501886	0.609510686236384
GO:0001540	amyloid-beta binding	2/321	83/18639	0.0240963855421687	1.39916676049994	0.419874427139861	0.611556230834146
GO:0030165	PDZ domain binding	2/321	83/18639	0.0240963855421687	1.39916676049994	0.419874427139861	0.611556230834146
GO:0008378	galactosyltransferase activity	1/321	32/18639	0.03125	1.81454439252336	0.426713742042884	0.616159929242958
GO:0051059	NF-kappaB binding	1/321	32/18639	0.03125	1.81454439252336	0.426713742042884	0.616159929242958
GO:0071813	lipoprotein particle binding	1/321	32/18639	0.03125	1.81454439252336	0.426713742042884	0.616159929242958
GO:0071814	protein-lipid complex binding	1/321	32/18639	0.03125	1.81454439252336	0.426713742042884	0.616159929242958
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/321	33/18639	0.0303030303030303	1.75955819881054	0.436603831192357	0.625052493373673
GO:0019956	chemokine binding	1/321	33/18639	0.0303030303030303	1.75955819881054	0.436603831192357	0.625052493373673
GO:0030296	protein tyrosine kinase activator activity	1/321	33/18639	0.0303030303030303	1.75955819881054	0.436603831192357	0.625052493373673
GO:0140416	transcription regulator inhibitor activity	1/321	33/18639	0.0303030303030303	1.75955819881054	0.436603831192357	0.625052493373673
GO:0050660	flavin adenine dinucleotide binding	2/321	86/18639	0.0232558139534884	1.35035861769181	0.437596000468945	0.625137143527064
GO:0000993	RNA polymerase II complex binding	1/321	36/18639	0.0277777777777778	1.61292834890966	0.465265131479064	0.654889995989439
GO:0004190	aspartic-type endopeptidase activity	1/321	36/18639	0.0277777777777778	1.61292834890966	0.465265131479064	0.654889995989439
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/321	36/18639	0.0277777777777778	1.61292834890966	0.465265131479064	0.654889995989439
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/321	36/18639	0.0277777777777778	1.61292834890966	0.465265131479064	0.654889995989439
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/321	36/18639	0.0277777777777778	1.61292834890966	0.465265131479064	0.654889995989439
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/321	36/18639	0.0277777777777778	1.61292834890966	0.465265131479064	0.654889995989439
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/321	36/18639	0.0277777777777778	1.61292834890966	0.465265131479064	0.654889995989439
GO:0022829	wide pore channel activity	1/321	37/18639	0.027027027027027	1.56933569083102	0.474492132113113	0.663694631556964
GO:0030551	cyclic nucleotide binding	1/321	37/18639	0.027027027027027	1.56933569083102	0.474492132113113	0.663694631556964
GO:0070001	aspartic-type peptidase activity	1/321	37/18639	0.027027027027027	1.56933569083102	0.474492132113113	0.663694631556964
GO:0051213	dioxygenase activity	2/321	93/18639	0.021505376344086	1.24871872173651	0.477762595589979	0.663972384616177
GO:0005501	retinoid binding	1/321	38/18639	0.0263157894736842	1.52803738317757	0.483560405717656	0.663972384616177
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/321	38/18639	0.0263157894736842	1.52803738317757	0.483560405717656	0.663972384616177
GO:0019840	isoprenoid binding	1/321	38/18639	0.0263157894736842	1.52803738317757	0.483560405717656	0.663972384616177
GO:0043531	ADP binding	1/321	38/18639	0.0263157894736842	1.52803738317757	0.483560405717656	0.663972384616177
GO:0000510	H3-H4 histone complex chaperone activity	3/321	151/18639	0.0198675496688742	1.15361762703472	0.483609736854767	0.663972384616177
GO:0140584	chromatin extrusion motor activity	3/321	151/18639	0.0198675496688742	1.15361762703472	0.483609736854767	0.663972384616177
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	3/321	151/18639	0.0198675496688742	1.15361762703472	0.483609736854767	0.663972384616177
GO:0140849	ATP-dependent H2AZ histone chaperone activity	3/321	151/18639	0.0198675496688742	1.15361762703472	0.483609736854767	0.663972384616177
GO:0015616	DNA translocase activity	3/321	152/18639	0.0197368421052632	1.14602803738318	0.487975687925032	0.667155548859655
GO:0140674	ATP-dependent histone chaperone activity	3/321	152/18639	0.0197368421052632	1.14602803738318	0.487975687925032	0.667155548859655
GO:0004867	serine-type endopeptidase inhibitor activity	2/321	95/18639	0.0210526315789474	1.22242990654206	0.488915484313568	0.667155548859655
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/321	39/18639	0.0256410256410256	1.48885693745507	0.492472674400233	0.66928335060478
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/321	39/18639	0.0256410256410256	1.48885693745507	0.492472674400233	0.66928335060478
GO:0004896	cytokine receptor activity	2/321	96/18639	0.0208333333333333	1.20969626168224	0.494435871705277	0.670309742911215
GO:0004386	helicase activity	3/321	155/18639	0.0193548387096774	1.12384684956286	0.500964986493581	0.670309742911215
GO:0004177	aminopeptidase activity	1/321	40/18639	0.025	1.45163551401869	0.501231613729133	0.670309742911215
GO:0004532	RNA exonuclease activity	1/321	40/18639	0.025	1.45163551401869	0.501231613729133	0.670309742911215
GO:0032451	demethylase activity	1/321	40/18639	0.025	1.45163551401869	0.501231613729133	0.670309742911215
GO:0050997	quaternary ammonium group binding	1/321	40/18639	0.025	1.45163551401869	0.501231613729133	0.670309742911215
GO:0061791	GTPase motor activity	1/321	40/18639	0.025	1.45163551401869	0.501231613729133	0.670309742911215
GO:1990606	membrane scission GTPase motor activity	1/321	40/18639	0.025	1.45163551401869	0.501231613729133	0.670309742911215
GO:0042626	ATPase-coupled transmembrane transporter activity	2/321	98/18639	0.0204081632653061	1.1850085828724	0.5053627332534	0.67448811011908
GO:0140318	protein transporter activity	1/321	41/18639	0.024390243902439	1.41622976977433	0.509839853526592	0.677763297346858
GO:0140828	metal cation:monoatomic cation antiporter activity	1/321	41/18639	0.024390243902439	1.41622976977433	0.509839853526592	0.677763297346858
GO:0043130	ubiquitin binding	2/321	100/18639	0.02	1.16130841121495	0.516135581251594	0.682241622189628
GO:0016859	cis-trans isomerase activity	1/321	42/18639	0.0238095238095238	1.38251001335113	0.518299978648539	0.682241622189628
GO:0043175	RNA polymerase core enzyme binding	1/321	42/18639	0.0238095238095238	1.38251001335113	0.518299978648539	0.682241622189628
GO:0048487	beta-tubulin binding	1/321	42/18639	0.0238095238095238	1.38251001335113	0.518299978648539	0.682241622189628
GO:0051879	Hsp90 protein binding	1/321	42/18639	0.0238095238095238	1.38251001335113	0.518299978648539	0.682241622189628
GO:0003689	DNA clamp loader activity	3/321	160/18639	0.01875	1.08872663551402	0.522234593306265	0.686072897088623
GO:0004866	endopeptidase inhibitor activity	3/321	161/18639	0.0186335403726708	1.0819643582748	0.526429228648025	0.687781159713876
GO:0008200	ion channel inhibitor activity	1/321	43/18639	0.0232558139534884	1.35035861769181	0.526614529751072	0.687781159713876
GO:0008375	acetylglucosaminyltransferase activity	1/321	43/18639	0.0232558139534884	1.35035861769181	0.526614529751072	0.687781159713876
GO:0001046	core promoter sequence-specific DNA binding	1/321	44/18639	0.0227272727272727	1.3196686491079	0.534786004043926	0.694392679669439
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/321	44/18639	0.0227272727272727	1.3196686491079	0.534786004043926	0.694392679669439
GO:0030547	signaling receptor inhibitor activity	1/321	44/18639	0.0227272727272727	1.3196686491079	0.534786004043926	0.694392679669439
GO:0140713	histone chaperone activity	3/321	164/18639	0.0182926829268293	1.06217232733075	0.538890230148861	0.698368383365062
GO:0004175	endopeptidase activity	7/321	405/18639	0.0172839506172839	1.00359986154379	0.54939733349457	0.707734297255474
GO:0004180	carboxypeptidase activity	1/321	46/18639	0.0217391304347826	1.2622917513206	0.550709498239038	0.707734297255474
GO:0004843	cysteine-type deubiquitinase activity	2/321	108/18639	0.0185185185185185	1.07528556593977	0.557646725656704	0.707734297255474
GO:0005496	steroid binding	2/321	108/18639	0.0185185185185185	1.07528556593977	0.557646725656704	0.707734297255474
GO:0005504	fatty acid binding	1/321	47/18639	0.0212765957446809	1.23543448001591	0.558466301932109	0.707734297255474
GO:0061749	forked DNA-dependent helicase activity	1/321	47/18639	0.0212765957446809	1.23543448001591	0.558466301932109	0.707734297255474
GO:0140359	ABC-type transporter activity	1/321	47/18639	0.0212765957446809	1.23543448001591	0.558466301932109	0.707734297255474
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/321	47/18639	0.0212765957446809	1.23543448001591	0.558466301932109	0.707734297255474
GO:0030414	peptidase inhibitor activity	3/321	169/18639	0.0177514792899408	1.03074711054582	0.559236192376525	0.707734297255474
GO:0009378	four-way junction helicase activity	1/321	48/18639	0.0208333333333333	1.20969626168224	0.566089597816349	0.707734297255474
GO:0032266	phosphatidylinositol-3-phosphate binding	1/321	48/18639	0.0208333333333333	1.20969626168224	0.566089597816349	0.707734297255474
GO:0036121	double-stranded DNA helicase activity	1/321	48/18639	0.0208333333333333	1.20969626168224	0.566089597816349	0.707734297255474
GO:0038187	pattern recognition receptor activity	1/321	48/18639	0.0208333333333333	1.20969626168224	0.566089597816349	0.707734297255474
GO:0043138	3'-5' DNA helicase activity	1/321	48/18639	0.0208333333333333	1.20969626168224	0.566089597816349	0.707734297255474
GO:0001222	transcription corepressor binding	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0005004	GPI-linked ephrin receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0005008	hepatocyte growth factor receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0005009	insulin receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0005011	macrophage colony-stimulating factor receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0005020	stem cell factor receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0008288	boss receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0016763	pentosyltransferase activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0036332	placental growth factor receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0038062	protein tyrosine kinase collagen receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0060175	brain-derived neurotrophic factor receptor activity	1/321	49/18639	0.0204081632653061	1.1850085828724	0.573581676730929	0.707734297255474
GO:0003823	antigen binding	3/321	174/18639	0.0172413793103448	1.00112794070255	0.579034255566713	0.70877944544318
GO:0005006	epidermal growth factor receptor activity	1/321	50/18639	0.02	1.16130841121495	0.580944790327991	0.70877944544318
GO:0005007	fibroblast growth factor receptor activity	1/321	50/18639	0.02	1.16130841121495	0.580944790327991	0.70877944544318
GO:0005017	platelet-derived growth factor receptor activity	1/321	50/18639	0.02	1.16130841121495	0.580944790327991	0.70877944544318
GO:0005019	platelet-derived growth factor beta-receptor activity	1/321	50/18639	0.02	1.16130841121495	0.580944790327991	0.70877944544318
GO:0032813	tumor necrosis factor receptor superfamily binding	1/321	50/18639	0.02	1.16130841121495	0.580944790327991	0.70877944544318
GO:0001664	G protein-coupled receptor binding	5/321	297/18639	0.0168350168350168	0.97753233267252	0.582619521834797	0.70877944544318
GO:0019787	ubiquitin-like protein transferase activity	8/321	479/18639	0.0167014613778706	0.969777378885138	0.584916629740802	0.70877944544318
GO:0003743	translation initiation factor activity	1/321	51/18639	0.0196078431372549	1.13853765805388	0.588181151740908	0.70877944544318
GO:0005010	insulin-like growth factor receptor activity	1/321	51/18639	0.0196078431372549	1.13853765805388	0.588181151740908	0.70877944544318
GO:0005021	vascular endothelial growth factor receptor activity	1/321	51/18639	0.0196078431372549	1.13853765805388	0.588181151740908	0.70877944544318
GO:0005030	neurotrophin receptor activity	1/321	51/18639	0.0196078431372549	1.13853765805388	0.588181151740908	0.70877944544318
GO:0005048	signal sequence binding	1/321	51/18639	0.0196078431372549	1.13853765805388	0.588181151740908	0.70877944544318
GO:0101005	deubiquitinase activity	2/321	115/18639	0.0173913043478261	1.00983340105648	0.591846748554203	0.711916196645091
GO:0030159	signaling receptor complex adaptor activity	1/321	52/18639	0.0192307692307692	1.1166427030913	0.595292936241186	0.714210847544088
GO:0004864	protein phosphatase inhibitor activity	1/321	53/18639	0.0188679245283019	1.0955739728443	0.602282281884193	0.714210847544088
GO:0005003	ephrin receptor activity	1/321	53/18639	0.0188679245283019	1.0955739728443	0.602282281884193	0.714210847544088
GO:0005005	transmembrane-ephrin receptor activity	1/321	53/18639	0.0188679245283019	1.0955739728443	0.602282281884193	0.714210847544088
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/321	53/18639	0.0188679245283019	1.0955739728443	0.602282281884193	0.714210847544088
GO:0017046	peptide hormone binding	1/321	53/18639	0.0188679245283019	1.0955739728443	0.602282281884193	0.714210847544088
GO:0038064	collagen receptor activity	1/321	53/18639	0.0188679245283019	1.0955739728443	0.602282281884193	0.714210847544088
GO:0051018	protein kinase A binding	1/321	53/18639	0.0188679245283019	1.0955739728443	0.602282281884193	0.714210847544088
GO:0022853	active monoatomic ion transmembrane transporter activity	2/321	118/18639	0.0169491525423729	0.984159670521147	0.605890305011083	0.717219972362943
GO:0050661	NADP binding	1/321	54/18639	0.0185185185185185	1.07528556593977	0.609151290143914	0.718541134500744
GO:0140463	chromatin-protein adaptor activity	1/321	54/18639	0.0185185185185185	1.07528556593977	0.609151290143914	0.718541134500744
GO:0032182	ubiquitin-like protein binding	2/321	120/18639	0.0166666666666667	0.967757009345794	0.6150479411824	0.723186125697782
GO:0008374	O-acyltransferase activity	1/321	55/18639	0.0181818181818182	1.05573491928632	0.615902026536909	0.723186125697782
GO:0061135	endopeptidase regulator activity	3/321	184/18639	0.016304347826087	0.946718813490451	0.61691565507943	0.723186125697782
GO:0033218	amide binding	4/321	247/18639	0.0161943319838057	0.940330697340043	0.617988943145809	0.723186125697782
GO:0004540	RNA nuclease activity	2/321	121/18639	0.0165289256198347	0.959759017533019	0.619565427090339	0.723186125697782
GO:0051082	unfolded protein binding	2/321	121/18639	0.0165289256198347	0.959759017533019	0.619565427090339	0.723186125697782
GO:0019212	phosphatase inhibitor activity	1/321	56/18639	0.0178571428571429	1.03688251001335	0.622536521235663	0.724933463060049
GO:0016755	aminoacyltransferase activity	8/321	496/18639	0.0161290322580645	0.936539041302382	0.624220422204483	0.724933463060049
GO:0042277	peptide binding	4/321	249/18639	0.0160642570281124	0.932777840333296	0.62430837042634	0.724933463060049
GO:0140597	protein carrier chaperone	3/321	188/18639	0.0159574468085106	0.926575860011931	0.631409939502896	0.73191117554834
GO:0017116	single-stranded DNA helicase activity	1/321	58/18639	0.0172413793103448	1.00112794070255	0.635464733127298	0.735339155777703
GO:0015459	potassium channel regulator activity	1/321	59/18639	0.0169491525423729	0.984159670521147	0.641762339319976	0.738312063932132
GO:0070063	RNA polymerase binding	1/321	59/18639	0.0169491525423729	0.984159670521147	0.641762339319976	0.738312063932132
GO:0019783	ubiquitin-like protein peptidase activity	2/321	127/18639	0.015748031496063	0.914416071822798	0.645815556675279	0.738312063932132
GO:0001098	basal transcription machinery binding	1/321	60/18639	0.0166666666666667	0.967757009345794	0.647951482973274	0.738312063932132
GO:0001099	basal RNA polymerase II transcription machinery binding	1/321	60/18639	0.0166666666666667	0.967757009345794	0.647951482973274	0.738312063932132
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/321	60/18639	0.0166666666666667	0.967757009345794	0.647951482973274	0.738312063932132
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/321	60/18639	0.0166666666666667	0.967757009345794	0.647951482973274	0.738312063932132
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/321	60/18639	0.0166666666666667	0.967757009345794	0.647951482973274	0.738312063932132
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/321	60/18639	0.0166666666666667	0.967757009345794	0.647951482973274	0.738312063932132
GO:0031490	chromatin DNA binding	2/321	128/18639	0.015625	0.907272196261682	0.65004891239823	0.739444433458089
GO:0015026	coreceptor activity	1/321	61/18639	0.0163934426229508	0.951892140340126	0.654034026380647	0.740207428505124
GO:0016836	hydro-lyase activity	1/321	61/18639	0.0163934426229508	0.951892140340126	0.654034026380647	0.740207428505124
GO:0019905	syntaxin binding	1/321	61/18639	0.0163934426229508	0.951892140340126	0.654034026380647	0.740207428505124
GO:0004842	ubiquitin-protein transferase activity	7/321	449/18639	0.0155902004454343	0.905251545490498	0.657602132306767	0.742634277073612
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/321	130/18639	0.0153846153846154	0.893314162473041	0.658395165047351	0.742634277073612
GO:0016758	hexosyltransferase activity	3/321	197/18639	0.0152284263959391	0.884244983158594	0.662619489458678	0.746142954516494
GO:0003730	mRNA 3'-UTR binding	4/321	262/18639	0.0152671755725191	0.886494970393094	0.66374945749186	0.746161302885145
GO:0005179	hormone activity	2/321	132/18639	0.0151515151515152	0.879779099405268	0.666581671820261	0.748089983449874
GO:0051087	protein-folding chaperone binding	2/321	134/18639	0.0149253731343284	0.866648068070861	0.674609573659646	0.755833468815991
GO:0016757	glycosyltransferase activity	4/321	267/18639	0.0149812734082397	0.869893940984984	0.678150159933726	0.758531898423366
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	4/321	268/18639	0.0149253731343284	0.866648068070861	0.680978421237944	0.760425903715704
GO:0050840	extracellular matrix binding	1/321	67/18639	0.0149253731343284	0.866648068070861	0.688391021368781	0.767424266750554
GO:0140223	general transcription initiation factor activity	1/321	68/18639	0.0147058823529412	0.853903243540407	0.693776896995564	0.772143722569814
GO:0002039	p53 binding	1/321	69/18639	0.0144927536231884	0.841527834213734	0.699069967700665	0.776744408556294
GO:0004518	nuclease activity	3/321	209/18639	0.0143540669856459	0.833474936278675	0.70119382416554	0.777814341375682
GO:0001217	DNA-binding transcription repressor activity	4/321	278/18639	0.0143884892086331	0.83547367713306	0.708305964341119	0.784404952245537
GO:0008194	UDP-glycosyltransferase activity	2/321	145/18639	0.0137931034482759	0.800902352562037	0.715988519199451	0.791604468421835
GO:0004521	RNA endonuclease activity	1/321	73/18639	0.0136986301369863	0.795416720010242	0.719345679081326	0.794005939018927
GO:0003678	DNA helicase activity	1/321	74/18639	0.0135135135135135	0.784667845415509	0.724198099474243	0.798047247775893
GO:0019842	vitamin binding	2/321	150/18639	0.0133333333333333	0.774205607476636	0.733291852005007	0.806741446376609
GO:0003724	RNA helicase activity	1/321	77/18639	0.012987012987013	0.754096370918801	0.738259245705352	0.810874909217354
GO:0008186	ATP-dependent activity, acting on RNA	1/321	79/18639	0.0126582278481013	0.735005323553768	0.747233981327087	0.816715770781644
GO:0016835	carbon-oxygen lyase activity	1/321	79/18639	0.0126582278481013	0.735005323553768	0.747233981327087	0.816715770781644
GO:0033293	monocarboxylic acid binding	1/321	79/18639	0.0126582278481013	0.735005323553768	0.747233981327087	0.816715770781644
GO:0061134	peptidase regulator activity	3/321	226/18639	0.0132743362831858	0.770779918947978	0.749977217570037	0.818379048488477
GO:0015101	organic cation transmembrane transporter activity	1/321	81/18639	0.0123456790123457	0.716857043959848	0.755901911253719	0.823502895186979
GO:0008135	translation factor activity, RNA binding	1/321	83/18639	0.0120481927710843	0.699583380249972	0.764273492130451	0.830953121175923
GO:0015079	potassium ion transmembrane transporter activity	2/321	160/18639	0.0125	0.725817757009346	0.765221008605291	0.830953121175923
GO:0004527	exonuclease activity	1/321	84/18639	0.0119047619047619	0.691255006675567	0.768351321890428	0.831656519655229
GO:0180051	translation factor activity	1/321	84/18639	0.0119047619047619	0.691255006675567	0.768351321890428	0.831656519655229
GO:0016209	antioxidant activity	1/321	86/18639	0.0116279069767442	0.675179308845903	0.776297211469497	0.838901825297682
GO:0015399	primary active transmembrane transporter activity	2/321	166/18639	0.0120481927710843	0.699583380249972	0.782747066989329	0.84450971800781
GO:0016874	ligase activity	2/321	167/18639	0.0119760479041916	0.695394258212547	0.785554154488612	0.846175696957187
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/321	91/18639	0.010989010989011	0.638081544623601	0.794993272214521	0.854968687614332
GO:0008201	heparin binding	2/321	172/18639	0.0116279069767442	0.675179308845903	0.799116932684192	0.857089832594732
GO:0140098	catalytic activity, acting on RNA	5/321	387/18639	0.0129198966408269	0.750199232051003	0.799524097569713	0.857089832594732
GO:0042562	hormone binding	1/321	94/18639	0.0106382978723404	0.617717240007954	0.805454497354115	0.860849880453218
GO:0140104	molecular carrier activity	3/321	249/18639	0.0120481927710843	0.699583380249972	0.805601306036071	0.860849880453218
GO:0004252	serine-type endopeptidase activity	2/321	176/18639	0.0113636363636364	0.659834324553951	0.809415660087313	0.863548554551751
GO:0005249	voltage-gated potassium channel activity	1/321	98/18639	0.0102040816326531	0.592504291436201	0.818579568079273	0.87193690081576
GO:0008013	beta-catenin binding	1/321	106/18639	0.00943396226415094	0.547786986422148	0.842240184977204	0.895715752277344
GO:0008236	serine-type peptidase activity	2/321	194/18639	0.0103092783505155	0.598612583100491	0.85015871602469	0.902704183417658
GO:0005200	structural constituent of cytoskeleton	1/321	112/18639	0.00892857142857143	0.518441255006676	0.857943311356888	0.906789081462384
GO:0043022	ribosome binding	1/321	112/18639	0.00892857142857143	0.518441255006676	0.857943311356888	0.906789081462384
GO:0017171	serine hydrolase activity	2/321	198/18639	0.0101010101010101	0.586519399603512	0.858066086040524	0.906789081462384
GO:0016829	lyase activity	2/321	200/18639	0.01	0.580654205607477	0.861875467162157	0.909380414171095
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/321	122/18639	0.00819672131147541	0.475946070170063	0.880728288646053	0.927811247473044
GO:0046982	protein heterodimerization activity	4/321	369/18639	0.010840108401084	0.629435453233037	0.882387152730996	0.928099517001204
GO:0005267	potassium channel activity	1/321	124/18639	0.00806451612903226	0.468269520651191	0.884827805999353	0.929128886976748
GO:0061659	ubiquitin-like protein ligase activity	4/321	372/18639	0.010752688172043	0.624359360868254	0.886139341459914	0.929128886976748
GO:0004519	endonuclease activity	1/321	127/18639	0.0078740157480315	0.457208035911399	0.890715185247998	0.932467459556497
GO:0005262	calcium channel activity	1/321	131/18639	0.00763358778625954	0.443247485196547	0.898100919467782	0.938732630332939
GO:0015297	antiporter activity	1/321	135/18639	0.00740740740740741	0.430114226375909	0.904988957395825	0.944458880771344
GO:0140767	enzyme-substrate adaptor activity	1/321	139/18639	0.00719424460431655	0.41773683856653	0.91141273914909	0.949683569564371
GO:0005125	cytokine activity	2/321	234/18639	0.00854700854700855	0.496285645818356	0.91381303125688	0.950706103947375
GO:0022843	voltage-gated monoatomic cation channel activity	1/321	143/18639	0.00699300699300699	0.4060518920332	0.917403464578601	0.952961738399477
GO:0015085	calcium ion transmembrane transporter activity	1/321	147/18639	0.00680272108843537	0.395002860957467	0.92299024291213	0.95585382572529
GO:0005539	glycosaminoglycan binding	2/321	242/18639	0.00826446280991736	0.47987950876651	0.923040933200392	0.95585382572529
GO:0046906	tetrapyrrole binding	1/321	152/18639	0.00657894736842105	0.382009345794392	0.929446864050602	0.960786108613529
GO:0003774	cytoskeletal motor activity	1/321	153/18639	0.0065359477124183	0.379512552684625	0.930671917149523	0.960786108613529
GO:0008083	growth factor activity	1/321	162/18639	0.00617283950617284	0.358428521979924	0.940785737863061	0.96973299133577
GO:0015081	sodium ion transmembrane transporter activity	1/321	164/18639	0.00609756097560976	0.354057442443583	0.942825373410973	0.970342550207913
GO:0061630	ubiquitin protein ligase activity	3/321	353/18639	0.0084985835694051	0.493473829128167	0.944577507619607	0.970654800774749
GO:0005244	voltage-gated monoatomic ion channel activity	1/321	173/18639	0.00578034682080925	0.33563826913727	0.951170831925203	0.974674824154839
GO:1901681	sulfur compound binding	2/321	275/18639	0.00727272727272727	0.422293967714528	0.952138235556716	0.974674824154839
GO:0022832	voltage-gated channel activity	1/321	175/18639	0.00571428571428571	0.331802403204272	0.952853746002119	0.974674824154839
GO:0043021	ribonucleoprotein complex binding	1/321	177/18639	0.00564971751412429	0.328053223507049	0.954478832336331	0.974848807416679
GO:0016853	isomerase activity	1/321	180/18639	0.00555555555555556	0.322585669781931	0.956812349827541	0.975026540276742
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1/321	181/18639	0.00552486187845304	0.320803428512418	0.957563378361338	0.975026540276742
GO:0015078	proton transmembrane transporter activity	1/321	185/18639	0.00540540540540541	0.313867138166204	0.960439520297911	0.976234900871953
GO:0031406	carboxylic acid binding	1/321	187/18639	0.0053475935828877	0.31051027037833	0.96180386470073	0.976234900871953
GO:0043177	organic acid binding	1/321	189/18639	0.00529100529100529	0.307224447411363	0.963121297725912	0.976234900871953
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	4/321	484/18639	0.00826446280991736	0.47987950876651	0.968902184548531	0.980610972277215
GO:0001216	DNA-binding transcription activator activity	4/321	491/18639	0.00814663951120163	0.473038049374726	0.971465772282909	0.98172257530852
GO:0005261	monoatomic cation channel activity	2/321	341/18639	0.00586510263929619	0.340559651382684	0.982056644822135	0.990930650648841
GO:0046873	metal ion transmembrane transporter activity	3/321	450/18639	0.00666666666666667	0.387102803738318	0.984797131146683	0.992122732342382
GO:0022804	active transmembrane transporter activity	3/321	457/18639	0.00656455142231947	0.381173439129635	0.986199611552278	0.992122732342382
GO:0015291	secondary active transmembrane transporter activity	1/321	287/18639	0.00348432055749129	0.20231853853919	0.993426745610004	0.997894931872117
GO:0022836	gated channel activity	1/321	318/18639	0.00314465408805031	0.182595662140716	0.996197991212634	0.998059104831575
GO:0005216	monoatomic ion channel activity	2/321	448/18639	0.00446428571428571	0.259220627503338	0.996572406939451	0.998059104831575
GO:0045182	translation regulator activity	1/321	356/18639	0.00280898876404494	0.163105113934684	0.998059104831575	0.998059104831575