ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0022853	active monoatomic ion transmembrane transporter activity	49/3563	118/18639	0.415254237288136	2.17230528453931	1.58460110435846e-08	1.99895082716106e-05
GO:0005085	guanyl-nucleotide exchange factor activity	79/3563	230/18639	0.343478260869565	1.79682607475381	3.00368268544112e-08	1.99895082716106e-05
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	32/3563	68/18639	0.470588235294118	2.4617721351802	1.55425884834544e-07	6.89572842382594e-05
GO:0140297	DNA-binding transcription factor binding	138/3563	488/18639	0.282786885245902	1.47933335787212	4.32694330764051e-07	0.000143979038561738
GO:0060589	nucleoside-triphosphatase regulator activity	138/3563	490/18639	0.281632653061224	1.47329526253387	5.56668735076789e-07	0.000148185217277441
GO:0030695	GTPase regulator activity	137/3563	489/18639	0.280163599182004	1.46561025123586	8.38985557777375e-07	0.000186114962900281
GO:0015399	primary active transmembrane transporter activity	58/3563	166/18639	0.349397590361446	1.82779166060819	1.04490386241195e-06	0.000198681005838614
GO:0009055	electron transfer activity	44/3563	116/18639	0.379310344827586	1.98427322964956	1.70552121526908e-06	0.000282600192850238
GO:0070411	I-SMAD binding	12/3563	16/18639	0.75	3.92344934044345	1.9712102655102e-06	0.000282600192850238
GO:0044389	ubiquitin-like protein ligase binding	96/3563	322/18639	0.298136645962733	1.55963203595267	2.12321707626024e-06	0.000282600192850238
GO:0031625	ubiquitin protein ligase binding	90/3563	302/18639	0.298013245033113	1.55898649289144	4.43902598433146e-06	0.000537122144104106
GO:0035925	mRNA 3'-UTR AU-rich region binding	17/3563	30/18639	0.566666666666667	2.96438394611283	5.42391127933778e-06	0.000571865803434147
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	46/3563	128/18639	0.359375	1.87998614229582	5.58546614924411e-06	0.000571865803434147
GO:0045296	cadherin binding	95/3563	334/18639	0.284431137724551	1.48793487960929	2.01816745007854e-05	0.00181298149650533
GO:0015078	proton transmembrane transporter activity	59/3563	185/18639	0.318918918918919	1.66834962944983	2.17301598752626e-05	0.00181298149650533
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	32/3563	82/18639	0.390243902439024	2.04146957551529	2.17939173133624e-05	0.00181298149650533
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	98/3563	349/18639	0.28080229226361	1.46895142450223	2.64937036950612e-05	0.00201473721916744
GO:0016791	phosphatase activity	80/3563	273/18639	0.293040293040293	1.53297165926972	2.84816140349913e-05	0.00201473721916744
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	32/3563	83/18639	0.385542168674699	2.01687355653318	2.90213473736528e-05	0.00201473721916744
GO:0004721	phosphoprotein phosphatase activity	56/3563	175/18639	0.32	1.67400505192254	3.1178865156016e-05	0.00201473721916744
GO:0140789	histone phosphatase activity	46/3563	136/18639	0.338235294117647	1.76939872216077	3.35499270990152e-05	0.00201473721916744
GO:0000995	RNA polymerase III general transcription initiation factor activity	9/3563	12/18639	0.75	3.92344934044345	4.23198835067321e-05	0.00201473721916744
GO:0033192	calmodulin-dependent protein phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:0140791	histone H2AXS140 phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:1990439	MAP kinase serine/threonine phosphatase activity	31/3563	81/18639	0.382716049382716	2.00208937537032	4.54110567806336e-05	0.00201473721916744
GO:0051020	GTPase binding	89/3563	315/18639	0.282539682539683	1.47804017481256	4.74678573903475e-05	0.00203805542537266
GO:0031434	mitogen-activated protein kinase kinase binding	8/3563	10/18639	0.8	4.18501262980634	5.50024570345354e-05	0.00228775844728021
GO:0033549	MAP kinase phosphatase activity	31/3563	82/18639	0.378048780487805	1.97767365128044	5.97665729274073e-05	0.00238514439011111
GO:0003954	NADH dehydrogenase activity	20/3563	44/18639	0.454545454545455	2.37784808511724	6.09278056076466e-05	0.00238514439011111
GO:0031267	small GTPase binding	81/3563	283/18639	0.286219081272085	1.49728808751905	6.28350440361408e-05	0.00238952696034581
GO:0008137	NADH dehydrogenase (ubiquinone) activity	19/3563	41/18639	0.463414634146341	2.42424512092441	6.68985054926628e-05	0.00247338641140928
GO:0019787	ubiquitin-like protein transferase activity	125/3563	479/18639	0.260960334029228	1.3651528672385	9.21401414822778e-05	0.00331455481926789
GO:0017018	myosin phosphatase activity	31/3563	84/18639	0.369047619047619	1.93058618339281	0.000101335636326745	0.00354941399870783
GO:0045309	protein phosphorylated amino acid binding	24/3563	59/18639	0.406779661016949	2.12797252363034	0.00010474978707317	0.00357492222036895
GO:0004722	protein serine/threonine phosphatase activity	36/3563	103/18639	0.349514563106796	1.82840357612898	0.000108187506771945	0.00359993928783647
GO:0003712	transcription coregulator activity	128/3563	495/18639	0.258585858585859	1.35273135508892	0.000117431772940653	0.00381223633619536
GO:0001221	transcription coregulator binding	39/3563	115/18639	0.339130434782609	1.77408144089617	0.000120431756919521	0.00381653972523528
GO:0140416	transcription regulator inhibitor activity	16/3563	33/18639	0.484848484848485	2.53637129079172	0.000128595935552008	0.00398049279580749
GO:0001784	phosphotyrosine residue binding	20/3563	47/18639	0.425531914893617	2.22607054776933	0.000187208768628915	0.00566306525102469
GO:0016755	aminoacyltransferase activity	127/3563	496/18639	0.256048387096774	1.33945716730193	0.000195277217277411	0.0057758661376941
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	23/3563	58/18639	0.396551724137931	2.0744674673609	0.000227895069038467	0.00659409428022173
GO:0004842	ubiquitin-protein transferase activity	116/3563	449/18639	0.258351893095768	1.35150741942521	0.000248582431461439	0.00703964289947182
GO:0003779	actin binding	114/3563	443/18639	0.257336343115124	1.34619480755622	0.000329041068656102	0.00912403463294315
GO:0001222	transcription corepressor binding	20/3563	49/18639	0.408163265306122	2.1352105254114	0.000366207430104213	0.00994738958099404
GO:0046332	SMAD binding	28/3563	79/18639	0.354430379746835	1.85411951953446	0.000465532058184475	0.0123924633888707
GO:0031386	protein tag activity	9/3563	15/18639	0.6	3.13875947235476	0.000550075233834322	0.0140798103121824
GO:0141047	molecular tag activity	9/3563	15/18639	0.6	3.13875947235476	0.000550075233834322	0.0140798103121824
GO:0019838	growth factor binding	42/3563	136/18639	0.308823529411765	1.61553796371201	0.000659636388616427	0.0165655855329899
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	30/3563	89/18639	0.337078651685393	1.76334801817683	0.000781380591801266	0.0189094103215906
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	30/3563	89/18639	0.337078651685393	1.76334801817683	0.000781380591801266	0.0189094103215906
GO:0140793	histone H2AXY142 phosphatase activity	30/3563	90/18639	0.333333333333333	1.74375526241931	0.00096078369993199	0.0228357697251693
GO:0004725	protein tyrosine phosphatase activity	32/3563	98/18639	0.326530612244898	1.70816842032912	0.000985386077415522	0.0230096292814046
GO:0051117	ATPase binding	28/3563	84/18639	0.333333333333333	1.74375526241931	0.00139576578705435	0.032030418320161
GO:0048185	activin binding	7/3563	11/18639	0.636363636363636	3.32898731916414	0.00148065414233979	0.0334025536178689
GO:0005160	transforming growth factor beta receptor binding	12/3563	26/18639	0.461538461538462	2.41443036334981	0.00154799160488101	0.0341690452695729
GO:0035591	signaling adaptor activity	39/3563	129/18639	0.302325581395349	1.58154547056635	0.00156597427606608	0.0341690452695729
GO:0051219	phosphoprotein binding	30/3563	93/18639	0.32258064516129	1.68750509266385	0.00173062954022185	0.0371527083554077
GO:0061659	ubiquitin-like protein ligase activity	94/3563	372/18639	0.252688172043011	1.32187898925335	0.00191346123710795	0.0401252237851051
GO:0042578	phosphoric ester hydrolase activity	92/3563	363/18639	0.253443526170799	1.32583044745931	0.0019293871692312	0.0401252237851051
GO:0022804	active transmembrane transporter activity	112/3563	457/18639	0.24507658643326	1.28206076186628	0.00232460021696496	0.0476006598273902
GO:0005080	protein kinase C binding	19/3563	52/18639	0.365384615384615	1.91142403765194	0.00243316851584919	0.0490688984029586
GO:0050431	transforming growth factor beta binding	11/3563	24/18639	0.458333333333333	2.39766348582655	0.00259365032668272	0.051524605743503
GO:0001098	basal transcription machinery binding	21/3563	60/18639	0.35	1.83094302554027	0.00272014608690772	0.0524712237923794
GO:0001099	basal RNA polymerase II transcription machinery binding	21/3563	60/18639	0.35	1.83094302554027	0.00272014608690772	0.0524712237923794
GO:0004674	protein serine/threonine kinase activity	106/3563	433/18639	0.244803695150115	1.28063319503312	0.00310092262024017	0.0588503703465443
GO:0004129	cytochrome-c oxidase activity	8/3563	15/18639	0.533333333333333	2.7900084198709	0.00313927595387276	0.0588503703465443
GO:0001618	virus receptor activity	26/3563	81/18639	0.320987654320988	1.67917173418156	0.00365901138939722	0.0676408911012181
GO:0004709	MAP kinase kinase kinase activity	11/3563	25/18639	0.44	2.30175694639349	0.00383991220660883	0.0700126458492651
GO:0061630	ubiquitin protein ligase activity	88/3563	353/18639	0.24929178470255	1.30411158435892	0.00391209377519603	0.0703648218214312
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	10/3563	22/18639	0.454545454545455	2.37784808511724	0.00435586310297107	0.0770828510788066
GO:0140272	exogenous protein binding	26/3563	82/18639	0.317073170731707	1.65869403010617	0.00440142500525117	0.0770828510788066
GO:0005528	FK506 binding	6/3563	10/18639	0.6	3.13875947235476	0.00502112111034376	0.0856809256136865
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	6/3563	10/18639	0.6	3.13875947235476	0.00502112111034376	0.0856809256136865
GO:0004879	nuclear receptor activity	20/3563	59/18639	0.338983050847458	1.77331043635862	0.00514292565457474	0.0866485322308731
GO:0016675	oxidoreductase activity, acting on a heme group of donors	8/3563	16/18639	0.5	2.61563289362896	0.00523424296688067	0.0870847173614771
GO:0050840	extracellular matrix binding	22/3563	67/18639	0.328358208955224	1.71772906447275	0.00530754988535268	0.087214183918573
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	11/3563	26/18639	0.423076923076923	2.21322783307066	0.00552065398120922	0.0896096396218228
GO:0003714	transcription corepressor activity	54/3563	204/18639	0.264705882352941	1.38474682603886	0.00604591548186113	0.0964723778447248
GO:0098531	ligand-modulated transcription factor activity	20/3563	60/18639	0.333333333333333	1.74375526241931	0.0063543154384082	0.0964723778447248
GO:0042171	lysophosphatidic acid acyltransferase activity	10/3563	23/18639	0.434782608695652	2.27446338576432	0.00640250092861	0.0964723778447248
GO:0071617	lysophospholipid acyltransferase activity	10/3563	23/18639	0.434782608695652	2.27446338576432	0.00640250092861	0.0964723778447248
GO:0051015	actin filament binding	55/3563	209/18639	0.263157894736842	1.37664889138367	0.00640526733685582	0.0964723778447248
GO:0098631	cell adhesion mediator activity	24/3563	76/18639	0.315789473684211	1.6519786696604	0.00641395248788261	0.0964723778447248
GO:0005518	collagen binding	23/3563	72/18639	0.319444444444444	1.67109879315184	0.0064508201564091	0.0964723778447248
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	68/3563	268/18639	0.253731343283582	1.3273360952744	0.00672033596890746	0.0993863019401759
GO:0140303	intramembrane lipid transporter activity	16/3563	45/18639	0.355555555555556	1.86000561324726	0.00703262905736309	0.102861860168684
GO:0001217	DNA-binding transcription repressor activity	70/3563	278/18639	0.251798561151079	1.31722519823041	0.00727880906045587	0.104982586705046
GO:0015095	magnesium ion transmembrane transporter activity	9/3563	20/18639	0.45	2.35406960426607	0.0073353723242444	0.104982586705046
GO:0140296	general transcription initiation factor binding	18/3563	53/18639	0.339622641509434	1.77665630510647	0.00755914618377744	0.107034293304338
GO:0003713	transcription coactivator activity	65/3563	256/18639	0.25390625	1.32825107879596	0.00777987465411202	0.10900013857498
GO:0017110	nucleoside diphosphate phosphatase activity	8/3563	17/18639	0.470588235294118	2.4617721351802	0.00824766965688795	0.112016819523652
GO:0032977	membrane insertase activity	8/3563	17/18639	0.470588235294118	2.4617721351802	0.00824766965688795	0.112016819523652
GO:0038191	neuropilin binding	8/3563	17/18639	0.470588235294118	2.4617721351802	0.00824766965688795	0.112016819523652
GO:0008474	palmitoyl-(protein) hydrolase activity	7/3563	14/18639	0.5	2.61563289362896	0.0089910443303646	0.117453865645512
GO:0098599	palmitoyl hydrolase activity	7/3563	14/18639	0.5	2.61563289362896	0.0089910443303646	0.117453865645512
GO:1990825	sequence-specific mRNA binding	7/3563	14/18639	0.5	2.61563289362896	0.0089910443303646	0.117453865645512
GO:0030215	semaphorin receptor binding	10/3563	24/18639	0.416666666666667	2.17969407802414	0.00912310850141521	0.117453865645512
GO:0005114	type II transforming growth factor beta receptor binding	6/3563	11/18639	0.545454545454545	2.85341770214069	0.00926968147194852	0.117453865645512
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	6/3563	11/18639	0.545454545454545	2.85341770214069	0.00926968147194852	0.117453865645512
GO:0034713	type I transforming growth factor beta receptor binding	6/3563	11/18639	0.545454545454545	2.85341770214069	0.00926968147194852	0.117453865645512
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	18/3563	54/18639	0.333333333333333	1.74375526241931	0.0093539517343533	0.117453865645512
GO:0061631	ubiquitin conjugating enzyme activity	13/3563	35/18639	0.371428571428571	1.94304157812437	0.00967905315515006	0.120400184574811
GO:0019789	SUMO transferase activity	11/3563	28/18639	0.392857142857143	2.05514013070847	0.0105707837651828	0.127906483558712
GO:0045499	chemorepellent activity	11/3563	28/18639	0.392857142857143	2.05514013070847	0.0105707837651828	0.127906483558712
GO:0046875	ephrin receptor binding	11/3563	28/18639	0.392857142857143	2.05514013070847	0.0105707837651828	0.127906483558712
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	9/3563	21/18639	0.428571428571429	2.24197105168197	0.0106909699377662	0.12819532420871
GO:0008375	acetylglucosaminyltransferase activity	15/3563	43/18639	0.348837209302326	1.82486015834579	0.0108218823297489	0.128268687345436
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	113/3563	484/18639	0.233471074380165	1.22134924371931	0.0108926754976728	0.128268687345436
GO:0003725	double-stranded RNA binding	23/3563	75/18639	0.306666666666667	1.60425484142576	0.0109861986156121	0.128268687345436
GO:0140313	molecular sequestering activity	18/3563	55/18639	0.327272727272727	1.71205062128441	0.0114737508690168	0.131881846409369
GO:0070063	RNA polymerase binding	19/3563	59/18639	0.322033898305085	1.68464491454069	0.0114938348486001	0.131881846409369
GO:0120015	sterol transfer activity	12/3563	32/18639	0.375	1.96172467022172	0.0117006299799055	0.13310716669448
GO:0017128	phospholipid scramblase activity	8/3563	18/18639	0.444444444444444	2.32500701655908	0.0123925311054529	0.135732367696036
GO:0098641	cadherin binding involved in cell-cell adhesion	8/3563	18/18639	0.444444444444444	2.32500701655908	0.0123925311054529	0.135732367696036
GO:0001216	DNA-binding transcription activator activity	114/3563	491/18639	0.232179226069246	1.21459124184807	0.0125019167489405	0.135732367696036
GO:0000993	RNA polymerase II complex binding	13/3563	36/18639	0.361111111111111	1.88906820095425	0.0125515010749486	0.135732367696036
GO:0016409	palmitoyltransferase activity	13/3563	36/18639	0.361111111111111	1.88906820095425	0.0125515010749486	0.135732367696036
GO:0019706	protein-cysteine S-palmitoyltransferase activity	10/3563	25/18639	0.4	2.09250631490317	0.0126452393646195	0.135732367696036
GO:0019707	protein-cysteine S-acyltransferase activity	10/3563	25/18639	0.4	2.09250631490317	0.0126452393646195	0.135732367696036
GO:0005096	GTPase activator activity	67/3563	271/18639	0.247232472324723	1.29333877397152	0.0128867392337128	0.137217999360573
GO:0004532	RNA exonuclease activity	14/3563	40/18639	0.35	1.83094302554027	0.0131650979762545	0.138458218616764
GO:0002020	protease binding	37/3563	136/18639	0.272058823529412	1.42321201565105	0.0132112650370617	0.138458218616764
GO:0005548	phospholipid transporter activity	21/3563	68/18639	0.308823529411765	1.61553796371201	0.013513889797316	0.139042689894491
GO:0001046	core promoter sequence-specific DNA binding	15/3563	44/18639	0.340909090909091	1.78338606383793	0.0135804280137369	0.139042689894491
GO:0001223	transcription coactivator binding	15/3563	44/18639	0.340909090909091	1.78338606383793	0.0135804280137369	0.139042689894491
GO:0050700	CARD domain binding	7/3563	15/18639	0.466666666666667	2.44125736738703	0.014111341659795	0.139464877323065
GO:0061578	K63-linked deubiquitinase activity	7/3563	15/18639	0.466666666666667	2.44125736738703	0.014111341659795	0.139464877323065
GO:0141050	histone H3K deacetylase activity	7/3563	15/18639	0.466666666666667	2.44125736738703	0.014111341659795	0.139464877323065
GO:0141051	histone H4K deacetylase activity	7/3563	15/18639	0.466666666666667	2.44125736738703	0.014111341659795	0.139464877323065
GO:0016417	S-acyltransferase activity	11/3563	29/18639	0.379310344827586	1.98427322964956	0.0141455735827301	0.139464877323065
GO:0004407	histone deacetylase activity	9/3563	22/18639	0.409090909090909	2.14006327660552	0.0150768131310859	0.141955717098744
GO:0033558	protein lysine deacetylase activity	9/3563	22/18639	0.409090909090909	2.14006327660552	0.0150768131310859	0.141955717098744
GO:0140311	protein sequestering activity	12/3563	33/18639	0.363636363636364	1.90227846809379	0.015254722284628	0.141955717098744
GO:0005025	transforming growth factor beta receptor activity, type I	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0005026	transforming growth factor beta receptor activity, type II	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0005527	macrolide binding	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0016361	activin receptor activity, type I	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0016362	activin receptor activity, type II	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0017002	activin receptor activity	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0070410	co-SMAD binding	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/3563	12/18639	0.5	2.61563289362896	0.015571400974017	0.141955717098744
GO:0005520	insulin-like growth factor binding	8/3563	19/18639	0.421052631578947	2.20263822621386	0.0178801608417402	0.160800635678083
GO:1990380	K48-linked deubiquitinase activity	8/3563	19/18639	0.421052631578947	2.20263822621386	0.0178801608417402	0.160800635678083
GO:0031624	ubiquitin conjugating enzyme binding	11/3563	30/18639	0.366666666666667	1.91813078866124	0.0185604223259248	0.16547830162454
GO:0019208	phosphatase regulator activity	32/3563	117/18639	0.273504273504274	1.43077354865174	0.0186489445857859	0.16547830162454
GO:0019955	cytokine binding	38/3563	144/18639	0.263888888888889	1.38047291608195	0.0197762365254575	0.174096740217662
GO:0001540	amyloid-beta binding	24/3563	83/18639	0.289156626506024	1.51265516739988	0.019960134050457	0.174096740217662
GO:0106310	protein serine kinase activity	85/3563	361/18639	0.235457063711911	1.23173848176433	0.0200126230302797	0.174096740217662
GO:0015485	cholesterol binding	17/3563	54/18639	0.314814814814815	1.64687997006268	0.0204640664883638	0.175504773301105
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	17/3563	54/18639	0.314814814814815	1.64687997006268	0.0204640664883638	0.175504773301105
GO:0043175	RNA polymerase core enzyme binding	14/3563	42/18639	0.333333333333333	1.74375526241931	0.0205700560743594	0.175504773301105
GO:0004713	protein tyrosine kinase activity	37/3563	140/18639	0.264285714285714	1.38254881520388	0.0207621801377561	0.176015680021359
GO:0005024	transforming growth factor beta receptor activity	7/3563	16/18639	0.4375	2.28867878192534	0.0210157517542838	0.177037756866783
GO:0019003	GDP binding	22/3563	75/18639	0.293333333333333	1.53450463092899	0.0213884465343267	0.179044165642697
GO:0019902	phosphatase binding	48/3563	190/18639	0.252631578947368	1.32158293572832	0.0216789410619025	0.180341690958702
GO:0016651	oxidoreductase activity, acting on NAD(P)H	25/3563	88/18639	0.284090909090909	1.48615505319828	0.0221303376191073	0.182953288018831
GO:0016411	acylglycerol O-acyltransferase activity	11/3563	31/18639	0.354838709677419	1.85625560193023	0.0239186665243999	0.19611215931762
GO:0016922	nuclear receptor binding	36/3563	137/18639	0.262773722627737	1.37463918497289	0.024274418505431	0.19611215931762
GO:0005338	nucleotide-sugar transmembrane transporter activity	6/3563	13/18639	0.461538461538462	2.41443036334981	0.0243114247087959	0.19611215931762
GO:0070123	transforming growth factor beta receptor activity, type III	6/3563	13/18639	0.461538461538462	2.41443036334981	0.0243114247087959	0.19611215931762
GO:0098632	cell-cell adhesion mediator activity	17/3563	55/18639	0.309090909090909	1.61693669787972	0.0244860497917558	0.196330917306186
GO:0000175	3'-5'-RNA exonuclease activity	12/3563	35/18639	0.342857142857143	1.79357684134558	0.0247280593787296	0.197084113970594
GO:0003727	single-stranded RNA binding	25/3563	89/18639	0.280898876404494	1.46945668181403	0.0253429428081666	0.200531410040499
GO:0032934	sterol binding	20/3563	68/18639	0.294117647058824	1.53860758448763	0.0266102340564305	0.200531410040499
GO:0140223	general transcription initiation factor activity	20/3563	68/18639	0.294117647058824	1.53860758448763	0.0266102340564305	0.200531410040499
GO:0019888	protein phosphatase regulator activity	29/3563	107/18639	0.271028037383178	1.41781969935028	0.0272342254006663	0.200531410040499
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0031419	cobalamin binding	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0043422	protein kinase B binding	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0099122	RNA polymerase II C-terminal domain binding	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	5/3563	10/18639	0.5	2.61563289362896	0.0272657616320793	0.200531410040499
GO:0042625	ATPase-coupled ion transmembrane transporter activity	9/3563	24/18639	0.375	1.96172467022172	0.0275711856028634	0.200531410040499
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	9/3563	24/18639	0.375	1.96172467022172	0.0275711856028634	0.200531410040499
GO:0046961	proton-transporting ATPase activity, rotational mechanism	9/3563	24/18639	0.375	1.96172467022172	0.0275711856028634	0.200531410040499
GO:0005178	integrin binding	41/3563	161/18639	0.254658385093168	1.33218569737624	0.0281891101448953	0.20391144349378
GO:0051019	mitogen-activated protein kinase binding	10/3563	28/18639	0.357142857142857	1.86830920973497	0.0292959211967542	0.209639092004731
GO:0051537	2 iron, 2 sulfur cluster binding	10/3563	28/18639	0.357142857142857	1.86830920973497	0.0292959211967542	0.209639092004731
GO:0030159	signaling receptor complex adaptor activity	16/3563	52/18639	0.307692307692308	1.60962024223321	0.0297609668301538	0.210941733730664
GO:0004659	prenyltransferase activity	7/3563	17/18639	0.411764705882353	2.15405061828268	0.0299534092224609	0.210941733730664
GO:0051787	misfolded protein binding	7/3563	17/18639	0.411764705882353	2.15405061828268	0.0299534092224609	0.210941733730664
GO:0044390	ubiquitin-like protein conjugating enzyme binding	12/3563	36/18639	0.333333333333333	1.74375526241931	0.0308163385306202	0.2125209667578
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	12/3563	36/18639	0.333333333333333	1.74375526241931	0.0308163385306202	0.2125209667578
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	12/3563	36/18639	0.333333333333333	1.74375526241931	0.0308163385306202	0.2125209667578
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	12/3563	36/18639	0.333333333333333	1.74375526241931	0.0308163385306202	0.2125209667578
GO:1990782	protein tyrosine kinase binding	31/3563	117/18639	0.264957264957265	1.38606187525637	0.0310949135925154	0.213336752534216
GO:0120013	lipid transfer activity	19/3563	65/18639	0.292307692307692	1.52913923012155	0.0320747600245199	0.218930797910954
GO:0019199	transmembrane receptor protein kinase activity	22/3563	78/18639	0.282051282051282	1.47548522204711	0.0329203390198914	0.223555975691201
GO:0003924	GTPase activity	77/3563	331/18639	0.232628398791541	1.21694098374278	0.0332999605943602	0.224986028178139
GO:0004705	JUN kinase activity	6/3563	14/18639	0.428571428571429	2.24197105168197	0.0358017099926194	0.233522523959301
GO:0019992	diacylglycerol binding	6/3563	14/18639	0.428571428571429	2.24197105168197	0.0358017099926194	0.233522523959301
GO:0046030	inositol trisphosphate phosphatase activity	6/3563	14/18639	0.428571428571429	2.24197105168197	0.0358017099926194	0.233522523959301
GO:0098821	BMP receptor activity	6/3563	14/18639	0.428571428571429	2.24197105168197	0.0358017099926194	0.233522523959301
GO:0098847	sequence-specific single stranded DNA binding	6/3563	14/18639	0.428571428571429	2.24197105168197	0.0358017099926194	0.233522523959301
GO:0017025	TBP-class protein binding	9/3563	25/18639	0.36	1.88325568341285	0.0359670303618758	0.233522523959301
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	9/3563	25/18639	0.36	1.88325568341285	0.0359670303618758	0.233522523959301
GO:0120020	cholesterol transfer activity	9/3563	25/18639	0.36	1.88325568341285	0.0359670303618758	0.233522523959301
GO:0043178	alcohol binding	25/3563	92/18639	0.271739130434783	1.4215396161027	0.037149013579444	0.239138210765702
GO:0043236	laminin binding	10/3563	29/18639	0.344827586206897	1.80388475422687	0.0372697883620301	0.239138210765702
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/3563	41/18639	0.317073170731707	1.65869403010617	0.0375922896075539	0.239138210765702
GO:0005319	lipid transporter activity	44/3563	178/18639	0.247191011235955	1.29312187999634	0.0378504579071233	0.239138210765702
GO:0071889	14-3-3 protein binding	11/3563	33/18639	0.333333333333333	1.74375526241931	0.0378505245006744	0.239138210765702
GO:0019213	deacetylase activity	12/3563	37/18639	0.324324324324324	1.69662674181338	0.0379099642911819	0.239138210765702
GO:0017124	SH3 domain binding	30/3563	115/18639	0.260869565217391	1.36467803145859	0.0406150403002397	0.252248345186439
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	7/3563	18/18639	0.388888888888889	2.03438113948919	0.0411285134787387	0.252248345186439
GO:0004706	JUN kinase kinase kinase activity	7/3563	18/18639	0.388888888888889	2.03438113948919	0.0411285134787387	0.252248345186439
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	7/3563	18/18639	0.388888888888889	2.03438113948919	0.0411285134787387	0.252248345186439
GO:0070628	proteasome binding	7/3563	18/18639	0.388888888888889	2.03438113948919	0.0411285134787387	0.252248345186439
GO:1990381	ubiquitin-specific protease binding	7/3563	18/18639	0.388888888888889	2.03438113948919	0.0411285134787387	0.252248345186439
GO:0005225	volume-sensitive anion channel activity	5/3563	11/18639	0.454545454545455	2.37784808511724	0.0422624950988549	0.252248345186439
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/3563	11/18639	0.454545454545455	2.37784808511724	0.0422624950988549	0.252248345186439
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/3563	11/18639	0.454545454545455	2.37784808511724	0.0422624950988549	0.252248345186439
GO:0045294	alpha-catenin binding	5/3563	11/18639	0.454545454545455	2.37784808511724	0.0422624950988549	0.252248345186439
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/3563	11/18639	0.454545454545455	2.37784808511724	0.0422624950988549	0.252248345186439
GO:1900750	oligopeptide binding	5/3563	11/18639	0.454545454545455	2.37784808511724	0.0422624950988549	0.252248345186439
GO:0032182	ubiquitin-like protein binding	31/3563	120/18639	0.258333333333333	1.35141032837497	0.0427934327066652	0.254277048806122
GO:0061133	endopeptidase activator activity	8/3563	22/18639	0.363636363636364	1.90227846809379	0.0442792851516092	0.260777559897309
GO:0070034	telomerase RNA binding	8/3563	22/18639	0.363636363636364	1.90227846809379	0.0442792851516092	0.260777559897309
GO:0042626	ATPase-coupled transmembrane transporter activity	26/3563	98/18639	0.26530612244898	1.38788684151741	0.0446971214822639	0.262078716708781
GO:0016859	cis-trans isomerase activity	13/3563	42/18639	0.30952380952381	1.61920131510364	0.045222946018986	0.263998864698554
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	12/3563	38/18639	0.315789473684211	1.6519786696604	0.0460777129388086	0.266649721398062
GO:0042162	telomeric DNA binding	12/3563	38/18639	0.315789473684211	1.6519786696604	0.0460777129388086	0.266649721398062
GO:0051721	protein phosphatase 2A binding	10/3563	30/18639	0.333333333333333	1.74375526241931	0.0466244713800828	0.268645763666191
GO:0004540	RNA nuclease activity	31/3563	121/18639	0.256198347107438	1.34024164797517	0.0473410932686927	0.270433455539184
GO:0051082	unfolded protein binding	31/3563	121/18639	0.256198347107438	1.34024164797517	0.0473410932686927	0.270433455539184
GO:0019903	protein phosphatase binding	36/3563	144/18639	0.25	1.30781644681448	0.048288721686937	0.274667899851766
GO:0005496	steroid binding	28/3563	108/18639	0.259259259259259	1.3562540929928	0.0500753406578917	0.27991072315552
GO:0000774	adenyl-nucleotide exchange factor activity	6/3563	15/18639	0.4	2.09250631490317	0.0502619555478356	0.27991072315552
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	6/3563	15/18639	0.4	2.09250631490317	0.0502619555478356	0.27991072315552
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	6/3563	15/18639	0.4	2.09250631490317	0.0502619555478356	0.27991072315552
GO:0120283	protein serine/threonine kinase binding	6/3563	15/18639	0.4	2.09250631490317	0.0502619555478356	0.27991072315552
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	54/3563	229/18639	0.235807860262009	1.23357359175514	0.0527383207942296	0.292477937404665
GO:0043539	protein serine/threonine kinase activator activity	20/3563	73/18639	0.273972602739726	1.43322350335834	0.0535748726829228	0.295884462825602
GO:0004712	protein serine/threonine/tyrosine kinase activity	13/3563	43/18639	0.302325581395349	1.58154547056635	0.0538665918668079	0.296266255267443
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	7/3563	19/18639	0.368421052631579	1.92730844793713	0.0546900525169879	0.299557448148604
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	12/3563	39/18639	0.307692307692308	1.60962024223321	0.0553785578786022	0.302085494001719
GO:0043130	ubiquitin binding	26/3563	100/18639	0.26	1.36012910468706	0.0556610524199165	0.302387186820036
GO:0005154	epidermal growth factor receptor binding	11/3563	35/18639	0.314285714285714	1.64411210456678	0.0566161070537781	0.306325359709669
GO:0070325	lipoprotein particle receptor binding	10/3563	31/18639	0.32258064516129	1.68750509266385	0.0574367594065985	0.309507395830699
GO:0008603	cAMP-dependent protein kinase regulator activity	5/3563	12/18639	0.416666666666667	2.17969407802414	0.0613275623308819	0.327819218724513
GO:0035259	nuclear glucocorticoid receptor binding	5/3563	12/18639	0.416666666666667	2.17969407802414	0.0613275623308819	0.327819218724513
GO:0061791	GTPase motor activity	12/3563	40/18639	0.3	1.56937973617738	0.0658600636475329	0.3492420108162
GO:1990606	membrane scission GTPase motor activity	12/3563	40/18639	0.3	1.56937973617738	0.0658600636475329	0.3492420108162
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	6/3563	16/18639	0.375	1.96172467022172	0.0678096778239667	0.349824345673254
GO:0004707	MAP kinase activity	6/3563	16/18639	0.375	1.96172467022172	0.0678096778239667	0.349824345673254
GO:0005159	insulin-like growth factor receptor binding	6/3563	16/18639	0.375	1.96172467022172	0.0678096778239667	0.349824345673254
GO:0005521	lamin binding	6/3563	16/18639	0.375	1.96172467022172	0.0678096778239667	0.349824345673254
GO:0017070	U6 snRNA binding	6/3563	16/18639	0.375	1.96172467022172	0.0678096778239667	0.349824345673254
GO:0034450	ubiquitin-ubiquitin ligase activity	6/3563	16/18639	0.375	1.96172467022172	0.0678096778239667	0.349824345673254
GO:0140328	floppase activity	6/3563	16/18639	0.375	1.96172467022172	0.0678096778239667	0.349824345673254
GO:0004860	protein kinase inhibitor activity	22/3563	84/18639	0.261904761904762	1.37009342047231	0.0689581599843455	0.35437571791183
GO:0070717	poly-purine tract binding	10/3563	32/18639	0.3125	1.6347705585181	0.0697631998511164	0.35713391923783
GO:0005525	GTP binding	84/3563	378/18639	0.222222222222222	1.16250350827954	0.0705981880502885	0.357940114182687
GO:0052745	inositol phosphate phosphatase activity	7/3563	20/18639	0.35	1.83094302554027	0.070725454720456	0.357940114182687
GO:0036408	histone H3K14 acetyltransferase activity	9/3563	28/18639	0.321428571428571	1.68147828876148	0.0710521513073194	0.357940114182687
GO:0097718	disordered domain specific binding	9/3563	28/18639	0.321428571428571	1.68147828876148	0.0710521513073194	0.357940114182687
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/3563	24/18639	0.333333333333333	1.74375526241931	0.071534237695413	0.357940114182687
GO:0050699	WW domain binding	8/3563	24/18639	0.333333333333333	1.74375526241931	0.071534237695413	0.357940114182687
GO:0046915	transition metal ion transmembrane transporter activity	13/3563	45/18639	0.288888888888889	1.5112545607634	0.0743593905081705	0.369317497022351
GO:0008408	3'-5' exonuclease activity	16/3563	58/18639	0.275862068965517	1.4431078033815	0.0743629520676108	0.369317497022351
GO:0017022	myosin binding	20/3563	76/18639	0.263157894736842	1.37664889138367	0.0768712570495707	0.380355550680218
GO:0003925	G protein activity	15/3563	54/18639	0.277777777777778	1.45312938534942	0.0781818591295282	0.383985440964583
GO:0017069	snRNA binding	15/3563	54/18639	0.277777777777778	1.45312938534942	0.0781818591295282	0.383985440964583
GO:0016758	hexosyltransferase activity	46/3563	197/18639	0.233502538071066	1.22151383864906	0.0790181272981067	0.386665909683015
GO:0019210	kinase inhibitor activity	23/3563	90/18639	0.255555555555556	1.33687903452147	0.08076580870595	0.393770298123148
GO:0030971	receptor tyrosine kinase binding	21/3563	81/18639	0.259259259259259	1.3562540929928	0.0812774359412777	0.394818493568761
GO:0005035	death receptor activity	5/3563	13/18639	0.384615384615385	2.01202530279151	0.0844626483446857	0.405384687857377
GO:0019855	calcium channel inhibitor activity	5/3563	13/18639	0.384615384615385	2.01202530279151	0.0844626483446857	0.405384687857377
GO:0140333	glycerophospholipid flippase activity	5/3563	13/18639	0.384615384615385	2.01202530279151	0.0844626483446857	0.405384687857377
GO:0031593	polyubiquitin modification-dependent protein binding	16/3563	59/18639	0.271186440677966	1.4186483490869	0.0846708814608195	0.405384687857377
GO:0010484	histone H3 acetyltransferase activity	9/3563	29/18639	0.310344827586207	1.62349627880418	0.0862542146326996	0.410072233489616
GO:0030276	clathrin binding	13/3563	46/18639	0.282608695652174	1.47840120074681	0.0862661347686646	0.410072233489616
GO:0003707	nuclear steroid receptor activity	8/3563	25/18639	0.32	1.67400505192254	0.0882717470288423	0.411081329792254
GO:0015662	P-type ion transporter activity	8/3563	25/18639	0.32	1.67400505192254	0.0882717470288423	0.411081329792254
GO:0019211	phosphatase activator activity	8/3563	25/18639	0.32	1.67400505192254	0.0882717470288423	0.411081329792254
GO:0140358	P-type transmembrane transporter activity	8/3563	25/18639	0.32	1.67400505192254	0.0882717470288423	0.411081329792254
GO:0004549	tRNA-specific ribonuclease activity	6/3563	17/18639	0.352941176470588	1.84632910138515	0.0884585516066063	0.411081329792254
GO:0005092	GDP-dissociation inhibitor activity	6/3563	17/18639	0.352941176470588	1.84632910138515	0.0884585516066063	0.411081329792254
GO:0009931	calcium-dependent protein serine/threonine kinase activity	7/3563	21/18639	0.333333333333333	1.74375526241931	0.0892580798722474	0.411081329792254
GO:0140312	cargo adaptor activity	7/3563	21/18639	0.333333333333333	1.74375526241931	0.0892580798722474	0.411081329792254
GO:1904047	S-adenosyl-L-methionine binding	7/3563	21/18639	0.333333333333333	1.74375526241931	0.0892580798722474	0.411081329792254
GO:0005109	frizzled binding	11/3563	38/18639	0.289473684210526	1.51431378052203	0.094784080260064	0.435026244228087
GO:0015035	protein-disulfide reductase activity	10/3563	34/18639	0.294117647058824	1.53860758448763	0.0990733289560182	0.452628934655366
GO:0043495	protein-membrane adaptor activity	13/3563	47/18639	0.276595744680851	1.44694585605007	0.0992995108334837	0.452628934655366
GO:0043995	histone H4K5 acetyltransferase activity	9/3563	30/18639	0.3	1.56937973617738	0.103238390312393	0.455340375861544
GO:0043996	histone H4K8 acetyltransferase activity	9/3563	30/18639	0.3	1.56937973617738	0.103238390312393	0.455340375861544
GO:0043997	histone H4K12 acetyltransferase activity	9/3563	30/18639	0.3	1.56937973617738	0.103238390312393	0.455340375861544
GO:0004197	cysteine-type endopeptidase activity	22/3563	88/18639	0.25	1.30781644681448	0.104291780481459	0.455340375861544
GO:0048156	tau protein binding	12/3563	43/18639	0.27906976744186	1.45988812667663	0.104667808274109	0.455340375861544
GO:0001094	TFIID-class transcription factor complex binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0003680	minor groove of adenine-thymine-rich DNA binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0004382	GDP phosphatase activity	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0008190	eukaryotic initiation factor 4E binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0033204	ribonuclease P RNA binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0043295	glutathione binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0050815	phosphoserine residue binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0098505	G-rich strand telomeric DNA binding	4/3563	10/18639	0.4	2.09250631490317	0.105763695813749	0.455340375861544
GO:0034237	protein kinase A regulatory subunit binding	8/3563	26/18639	0.307692307692308	1.60962024223321	0.107078540679687	0.455340375861544
GO:0050750	low-density lipoprotein particle receptor binding	8/3563	26/18639	0.307692307692308	1.60962024223321	0.107078540679687	0.455340375861544
GO:0070412	R-SMAD binding	8/3563	26/18639	0.307692307692308	1.60962024223321	0.107078540679687	0.455340375861544
GO:0097602	cullin family protein binding	8/3563	26/18639	0.307692307692308	1.60962024223321	0.107078540679687	0.455340375861544
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	16/3563	61/18639	0.262295081967213	1.3721352884611	0.107918549445851	0.457450921377156
GO:0003697	single-stranded DNA binding	29/3563	121/18639	0.239669421487603	1.25377444488	0.108455128524611	0.457780590682482
GO:0008093	cytoskeletal anchor activity	7/3563	22/18639	0.318181818181818	1.66449365958207	0.110248184075212	0.457780590682482
GO:0008649	rRNA methyltransferase activity	7/3563	22/18639	0.318181818181818	1.66449365958207	0.110248184075212	0.457780590682482
GO:0004527	exonuclease activity	21/3563	84/18639	0.25	1.30781644681448	0.11053243752809	0.457780590682482
GO:0008174	mRNA methyltransferase activity	5/3563	14/18639	0.357142857142857	1.86830920973497	0.111496502984723	0.457780590682482
GO:0008559	ABC-type xenobiotic transporter activity	5/3563	14/18639	0.357142857142857	1.86830920973497	0.111496502984723	0.457780590682482
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/3563	14/18639	0.357142857142857	1.86830920973497	0.111496502984723	0.457780590682482
GO:0044548	S100 protein binding	5/3563	14/18639	0.357142857142857	1.86830920973497	0.111496502984723	0.457780590682482
GO:0061665	SUMO ligase activity	5/3563	14/18639	0.357142857142857	1.86830920973497	0.111496502984723	0.457780590682482
GO:0071933	Arp2/3 complex binding	5/3563	14/18639	0.357142857142857	1.86830920973497	0.111496502984723	0.457780590682482
GO:0000900	mRNA regulatory element binding translation repressor activity	6/3563	18/18639	0.333333333333333	1.74375526241931	0.11212357067054	0.457780590682482
GO:0035615	clathrin adaptor activity	6/3563	18/18639	0.333333333333333	1.74375526241931	0.11212357067054	0.457780590682482
GO:0016504	peptidase activator activity	15/3563	57/18639	0.263157894736842	1.37664889138367	0.114384821359558	0.465584701007866
GO:0141003	histone H2AX kinase activity	77/3563	354/18639	0.217514124293785	1.13787419666345	0.115151155928638	0.467274965064078
GO:0019205	nucleobase-containing compound kinase activity	12/3563	44/18639	0.272727272727273	1.42670885107034	0.120080483732162	0.48579672901978
GO:0035173	histone kinase activity	78/3563	360/18639	0.216666666666667	1.13344092057255	0.12085417754811	0.486334362266027
GO:0034212	protein N-acetyltransferase activity	14/3563	53/18639	0.264150943396226	1.38184379286058	0.121309547913089	0.486334362266027
GO:0051018	protein kinase A binding	14/3563	53/18639	0.264150943396226	1.38184379286058	0.121309547913089	0.486334362266027
GO:0019001	guanyl nucleotide binding	86/3563	400/18639	0.215	1.12472214426045	0.123494162863622	0.492127936441558
GO:0032561	guanyl ribonucleotide binding	86/3563	400/18639	0.215	1.12472214426045	0.123494162863622	0.492127936441558
GO:0051536	iron-sulfur cluster binding	19/3563	76/18639	0.25	1.30781644681448	0.12438964000251	0.49421674878609
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	17/3563	67/18639	0.253731343283582	1.3273360952744	0.126743006962871	0.499217763455293
GO:0015036	disulfide oxidoreductase activity	11/3563	40/18639	0.275	1.43859809149593	0.127108005093196	0.499217763455293
GO:0030331	nuclear estrogen receptor binding	11/3563	40/18639	0.275	1.43859809149593	0.127108005093196	0.499217763455293
GO:0005385	zinc ion transmembrane transporter activity	8/3563	27/18639	0.296296296296296	1.55000467770605	0.127898765843918	0.499217763455293
GO:0015252	proton channel activity	8/3563	27/18639	0.296296296296296	1.55000467770605	0.127898765843918	0.499217763455293
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	8/3563	27/18639	0.296296296296296	1.55000467770605	0.127898765843918	0.499217763455293
GO:0140996	histone H3 kinase activity	77/3563	357/18639	0.215686274509804	1.12831222862426	0.131547977130207	0.510896960749029
GO:0042277	peptide binding	55/3563	249/18639	0.220883534136546	1.15550047509713	0.132131365550252	0.510896960749029
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	7/3563	23/18639	0.304347826086957	1.59212437003502	0.133596814046538	0.510896960749029
GO:0140102	catalytic activity, acting on a rRNA	7/3563	23/18639	0.304347826086957	1.59212437003502	0.133596814046538	0.510896960749029
GO:0005484	SNAP receptor activity	10/3563	36/18639	0.277777777777778	1.45312938534942	0.134551684068048	0.510896960749029
GO:0055106	ubiquitin-protein transferase regulator activity	10/3563	36/18639	0.277777777777778	1.45312938534942	0.134551684068048	0.510896960749029
GO:0051540	metal cluster binding	19/3563	77/18639	0.246753246753247	1.29083181763507	0.136984116294646	0.510896960749029
GO:0008301	DNA binding, bending	6/3563	19/18639	0.315789473684211	1.6519786696604	0.138631348279872	0.510896960749029
GO:0042800	histone H3K4 methyltransferase activity	6/3563	19/18639	0.315789473684211	1.6519786696604	0.138631348279872	0.510896960749029
GO:0019887	protein kinase regulator activity	56/3563	255/18639	0.219607843137255	1.14882699641743	0.139855741938318	0.510896960749029
GO:0016407	acetyltransferase activity	23/3563	96/18639	0.239583333333333	1.25332409486388	0.140789085624787	0.510896960749029
GO:0035401	histone H3Y41 kinase activity	27/3563	115/18639	0.234782608695652	1.22821022831273	0.141861870768958	0.510896960749029
GO:0140801	histone H2AXY142 kinase activity	27/3563	115/18639	0.234782608695652	1.22821022831273	0.141861870768958	0.510896960749029
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0010854	adenylate cyclase regulator activity	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0015217	ADP transmembrane transporter activity	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0032050	clathrin heavy chain binding	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0140537	transcription regulator activator activity	4/3563	11/18639	0.363636363636364	1.90227846809379	0.14205009622226	0.510896960749029
GO:0005041	low-density lipoprotein particle receptor activity	5/3563	15/18639	0.333333333333333	1.74375526241931	0.142113776703166	0.510896960749029
GO:0015929	hexosaminidase activity	5/3563	15/18639	0.333333333333333	1.74375526241931	0.142113776703166	0.510896960749029
GO:0016846	carbon-sulfur lyase activity	5/3563	15/18639	0.333333333333333	1.74375526241931	0.142113776703166	0.510896960749029
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/3563	15/18639	0.333333333333333	1.74375526241931	0.142113776703166	0.510896960749029
GO:0042809	nuclear vitamin D receptor binding	5/3563	15/18639	0.333333333333333	1.74375526241931	0.142113776703166	0.510896960749029
GO:0048531	beta-1,3-galactosyltransferase activity	5/3563	15/18639	0.333333333333333	1.74375526241931	0.142113776703166	0.510896960749029
GO:0140776	protein-containing complex destabilizing activity	5/3563	15/18639	0.333333333333333	1.74375526241931	0.142113776703166	0.510896960749029
GO:0030515	snoRNA binding	9/3563	32/18639	0.28125	1.47129350266629	0.142406290336506	0.510896960749029
GO:0015605	organophosphate ester transmembrane transporter activity	13/3563	50/18639	0.26	1.36012910468706	0.14510049476192	0.519163329376654
GO:0033218	amide binding	54/3563	247/18639	0.218623481781377	1.14367754053412	0.153078531790758	0.546240015585787
GO:0004180	carboxypeptidase activity	12/3563	46/18639	0.260869565217391	1.36467803145859	0.15450875971183	0.549570315566158
GO:0002039	p53 binding	17/3563	69/18639	0.246376811594203	1.28886258526645	0.154837617082877	0.549570315566158
GO:0016757	glycosyltransferase activity	58/3563	267/18639	0.217228464419476	1.13637983393618	0.155575556563594	0.550720919643999
GO:0019207	kinase regulator activity	62/3563	287/18639	0.21602787456446	1.13009922930311	0.157592934846881	0.554532204387809
GO:0004714	transmembrane receptor protein tyrosine kinase activity	15/3563	60/18639	0.25	1.30781644681448	0.159028816556019	0.554532204387809
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	7/3563	24/18639	0.291666666666667	1.5257858546169	0.159151992544059	0.554532204387809
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	7/3563	24/18639	0.291666666666667	1.5257858546169	0.159151992544059	0.554532204387809
GO:0070300	phosphatidic acid binding	7/3563	24/18639	0.291666666666667	1.5257858546169	0.159151992544059	0.554532204387809
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	7/3563	24/18639	0.291666666666667	1.5257858546169	0.159151992544059	0.554532204387809
GO:0031072	heat shock protein binding	30/3563	131/18639	0.229007633587786	1.19799979860869	0.159839140017525	0.555472311653593
GO:0160215	deacylase activity	16/3563	65/18639	0.246153846153846	1.28769619378657	0.164848353091733	0.571388432200772
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/3563	20/18639	0.3	1.56937973617738	0.16773387409105	0.57837768501344
GO:0061608	nuclear import signal receptor activity	6/3563	20/18639	0.3	1.56937973617738	0.16773387409105	0.57837768501344
GO:0042826	histone deacetylase binding	29/3563	127/18639	0.228346456692913	1.19454100653921	0.168823535297328	0.58063081519572
GO:0000287	magnesium ion binding	50/3563	230/18639	0.217391304347826	1.13723169288216	0.174593287496034	0.592677004085645
GO:0004181	metallocarboxypeptidase activity	8/3563	29/18639	0.275862068965517	1.4431078033815	0.175164343858884	0.592677004085645
GO:0015026	coreceptor activity	15/3563	61/18639	0.245901639344262	1.28637683293228	0.175695208004988	0.592677004085645
GO:0015562	efflux transmembrane transporter activity	5/3563	16/18639	0.3125	1.6347705585181	0.175888367102802	0.592677004085645
GO:0030275	LRR domain binding	5/3563	16/18639	0.3125	1.6347705585181	0.175888367102802	0.592677004085645
GO:0031435	mitogen-activated protein kinase kinase kinase binding	5/3563	16/18639	0.3125	1.6347705585181	0.175888367102802	0.592677004085645
GO:0043023	ribosomal large subunit binding	5/3563	16/18639	0.3125	1.6347705585181	0.175888367102802	0.592677004085645
GO:0140327	flippase activity	5/3563	16/18639	0.3125	1.6347705585181	0.175888367102802	0.592677004085645
GO:0048306	calcium-dependent protein binding	19/3563	80/18639	0.2375	1.24242562447376	0.178925583327239	0.593617419013547
GO:0000340	RNA 7-methylguanosine cap binding	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0004526	ribonuclease P activity	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0005095	GTPase inhibitor activity	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0005247	voltage-gated chloride channel activity	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0016801	hydrolase activity, acting on ether bonds	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0016803	ether hydrolase activity	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0042301	phosphate ion binding	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0043047	single-stranded telomeric DNA binding	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0045295	gamma-catenin binding	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0070008	serine-type exopeptidase activity	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0097677	STAT family protein binding	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/3563	12/18639	0.333333333333333	1.74375526241931	0.182411363167949	0.593617419013547
GO:0043021	ribonucleoprotein complex binding	39/3563	177/18639	0.220338983050847	1.1526517836331	0.184030550006244	0.597426005020272
GO:0140857	histone H3T45 kinase activity	53/3563	246/18639	0.215447154471545	1.12706132814907	0.184815826688886	0.598515487403667
GO:0008139	nuclear localization sequence binding	7/3563	25/18639	0.28	1.46475442043222	0.186716532466643	0.603203166779375
GO:0008376	acetylgalactosaminyltransferase activity	9/3563	34/18639	0.264705882352941	1.38474682603886	0.187977843698976	0.605807530177572
GO:0005201	extracellular matrix structural constituent	37/3563	168/18639	0.220238095238095	1.1521240126699	0.192252123891665	0.618085934540594
GO:0140030	modification-dependent protein binding	38/3563	173/18639	0.219653179190751	1.14906416136301	0.193303204667885	0.619063217023229
GO:0035402	histone H3T11 kinase activity	53/3563	247/18639	0.214574898785425	1.12249832682053	0.193486324779612	0.619063217023229
GO:0016776	phosphotransferase activity, phosphate group as acceptor	10/3563	39/18639	0.256410256410256	1.34135020186101	0.198439102224224	0.631871878135029
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	10/3563	39/18639	0.256410256410256	1.34135020186101	0.198439102224224	0.631871878135029
GO:0072542	protein phosphatase activator activity	6/3563	21/18639	0.285714285714286	1.49464736778798	0.199124191778571	0.632540093692789
GO:0016251	RNA polymerase II general transcription initiation factor activity	13/3563	53/18639	0.245283018867925	1.28314066479911	0.200337696731664	0.633371673040012
GO:1901505	carbohydrate derivative transmembrane transporter activity	13/3563	53/18639	0.245283018867925	1.28314066479911	0.200337696731664	0.633371673040012
GO:0008187	poly-pyrimidine tract binding	8/3563	30/18639	0.266666666666667	1.39500420993545	0.201319236057609	0.63496659524331
GO:0004679	AMP-activated protein kinase activity	53/3563	248/18639	0.213709677419355	1.1179721238898	0.202372988180864	0.636781199216855
GO:0016790	thiolester hydrolase activity	11/3563	44/18639	0.25	1.30781644681448	0.207118129975008	0.640568398762355
GO:0008013	beta-catenin binding	24/3563	106/18639	0.226415094339623	1.18443753673764	0.208652494596317	0.640568398762355
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	5/3563	17/18639	0.294117647058824	1.53860758448763	0.212317456892884	0.640568398762355
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/3563	17/18639	0.294117647058824	1.53860758448763	0.212317456892884	0.640568398762355
GO:0019198	transmembrane receptor protein phosphatase activity	5/3563	17/18639	0.294117647058824	1.53860758448763	0.212317456892884	0.640568398762355
GO:0032183	SUMO binding	5/3563	17/18639	0.294117647058824	1.53860758448763	0.212317456892884	0.640568398762355
GO:0048038	quinone binding	5/3563	17/18639	0.294117647058824	1.53860758448763	0.212317456892884	0.640568398762355
GO:0010485	histone H4 acetyltransferase activity	9/3563	35/18639	0.257142857142857	1.34518263100918	0.212873791154305	0.640568398762355
GO:0060590	ATPase regulator activity	12/3563	49/18639	0.244897959183673	1.28112631524684	0.214412745272946	0.640568398762355
GO:1990841	promoter-specific chromatin binding	16/3563	68/18639	0.235294117647059	1.2308860675901	0.216014486911832	0.640568398762355
GO:0004112	cyclic-nucleotide phosphodiesterase activity	7/3563	26/18639	0.269230769230769	1.40841771195406	0.216056845230259	0.640568398762355
GO:0005112	Notch binding	7/3563	26/18639	0.269230769230769	1.40841771195406	0.216056845230259	0.640568398762355
GO:0008143	poly(A) binding	7/3563	26/18639	0.269230769230769	1.40841771195406	0.216056845230259	0.640568398762355
GO:0008157	protein phosphatase 1 binding	7/3563	26/18639	0.269230769230769	1.40841771195406	0.216056845230259	0.640568398762355
GO:0004521	RNA endonuclease activity	17/3563	73/18639	0.232876712328767	1.21823997785459	0.219999148906617	0.640568398762355
GO:0004676	3-phosphoinositide-dependent protein kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0004711	ribosomal protein S6 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0035175	histone H3S10 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0035979	histone H2AXS139 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0044022	histone H3S28 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0044023	histone H4S1 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0044024	histone H2AS1 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0044025	histone H2BS14 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0072354	histone H3T3 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0072371	histone H2AS121 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0072518	Rho-dependent protein serine/threonine kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0140823	histone H2BS36 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0140855	histone H3S57 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0140995	histone H2A kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0140997	histone H4 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0140998	histone H2B kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:1990244	histone H2AT120 kinase activity	52/3563	245/18639	0.212244897959184	1.11030947321393	0.220636389991963	0.640568398762355
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	10/3563	40/18639	0.25	1.30781644681448	0.222216134601233	0.640568398762355
GO:0070888	E-box binding	14/3563	59/18639	0.23728813559322	1.24131730545103	0.225919324631522	0.640568398762355
GO:0004535	poly(A)-specific ribonuclease activity	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0030955	potassium ion binding	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0031994	insulin-like growth factor I binding	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0035325	Toll-like receptor binding	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0045159	myosin II binding	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0046975	histone H3K36 methyltransferase activity	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0070700	BMP receptor binding	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0140852	histone ubiquitin ligase activity	4/3563	13/18639	0.307692307692308	1.60962024223321	0.225944125311622	0.640568398762355
GO:0004677	DNA-dependent protein kinase activity	52/3563	246/18639	0.211382113821138	1.10579602007078	0.230237778093819	0.640568398762355
GO:0032931	histone H3K56 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0034062	5'-3' RNA polymerase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0043992	histone H3K9 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0043993	histone H3K18 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0043994	histone H3K23 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0043999	histone H2AK5 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0044012	histone H2AK9 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0044014	histone H2BK5 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0044015	histone H2BK12 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0044016	histone H3K4 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0044017	histone H3K27 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0044018	histone H3K36 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0097747	RNA polymerase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0140908	histone H3K122 acetyltransferase activity	6/3563	22/18639	0.272727272727273	1.42670885107034	0.232452694667331	0.640568398762355
GO:0008080	N-acetyltransferase activity	16/3563	69/18639	0.231884057971014	1.2130471390743	0.234482975916799	0.644828183771198
GO:0035403	histone H3T6 kinase activity	52/3563	247/18639	0.210526315789474	1.10131911310693	0.240038165644274	0.658743914376347
GO:0008374	O-acyltransferase activity	13/3563	55/18639	0.236363636363636	1.23648100426096	0.241694252730421	0.661923971983932
GO:0019209	kinase activator activity	32/3563	148/18639	0.216216216216216	1.13108449454225	0.246685447413943	0.673442832548365
GO:0023026	MHC class II protein complex binding	7/3563	27/18639	0.259259259259259	1.3562540929928	0.246912173015479	0.673442832548365
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	51/3563	243/18639	0.209876543209877	1.09791998004179	0.250168664531128	0.675882788761642
GO:0008308	voltage-gated monoatomic anion channel activity	5/3563	18/18639	0.277777777777778	1.45312938534942	0.2508535669784	0.675882788761642
GO:0030228	lipoprotein particle receptor activity	5/3563	18/18639	0.277777777777778	1.45312938534942	0.2508535669784	0.675882788761642
GO:0031690	adrenergic receptor binding	5/3563	18/18639	0.277777777777778	1.45312938534942	0.2508535669784	0.675882788761642
GO:0050811	GABA receptor binding	5/3563	18/18639	0.277777777777778	1.45312938534942	0.2508535669784	0.675882788761642
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	5/3563	18/18639	0.277777777777778	1.45312938534942	0.2508535669784	0.675882788761642
GO:0097110	scaffold protein binding	16/3563	70/18639	0.228571428571429	1.19571789423038	0.253574098209019	0.680506779190642
GO:0030291	protein serine/threonine kinase inhibitor activity	11/3563	46/18639	0.239130434782609	1.25095486217037	0.253592308398616	0.680506779190642
GO:0008378	galactosyltransferase activity	8/3563	32/18639	0.25	1.30781644681448	0.257754016188466	0.687025813542233
GO:0042910	xenobiotic transmembrane transporter activity	8/3563	32/18639	0.25	1.30781644681448	0.257754016188466	0.687025813542233
GO:0140142	nucleocytoplasmic carrier activity	8/3563	32/18639	0.25	1.30781644681448	0.257754016188466	0.687025813542233
GO:0051087	protein-folding chaperone binding	29/3563	134/18639	0.216417910447761	1.13213961067522	0.258086331157864	0.687025813542233
GO:0005010	insulin-like growth factor receptor activity	12/3563	51/18639	0.235294117647059	1.2308860675901	0.259001934745919	0.688086976340954
GO:0004518	nuclease activity	44/3563	209/18639	0.210526315789474	1.10131911310693	0.261624761766766	0.693670434086784
GO:0043394	proteoglycan binding	9/3563	37/18639	0.243243243243243	1.27247005636004	0.266135061386576	0.698214987070941
GO:0000295	adenine nucleotide transmembrane transporter activity	6/3563	23/18639	0.260869565217391	1.36467803145859	0.26734300547467	0.698214987070941
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	6/3563	23/18639	0.260869565217391	1.36467803145859	0.26734300547467	0.698214987070941
GO:0044013	histone H2B acetyltransferase activity	6/3563	23/18639	0.260869565217391	1.36467803145859	0.26734300547467	0.698214987070941
GO:0070577	lysine-acetylated histone binding	6/3563	23/18639	0.260869565217391	1.36467803145859	0.26734300547467	0.698214987070941
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	6/3563	23/18639	0.260869565217391	1.36467803145859	0.26734300547467	0.698214987070941
GO:0005161	platelet-derived growth factor receptor binding	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0005347	ATP transmembrane transporter activity	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0005545	1-phosphatidylinositol binding	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0015926	glucosidase activity	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0016530	metallochaperone activity	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0034236	protein kinase A catalytic subunit binding	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0042813	Wnt receptor activity	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0070742	C2H2 zinc finger domain binding	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:1901612	cardiolipin binding	4/3563	14/18639	0.285714285714286	1.49464736778798	0.271723174242382	0.698214987070941
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	28/3563	130/18639	0.215384615384615	1.12673416956325	0.271732053570809	0.698214987070941
GO:0008194	UDP-glycosyltransferase activity	31/3563	145/18639	0.213793103448276	1.11840854762066	0.273018013655048	0.700167584151964
GO:0003735	structural constituent of ribosome	37/3563	175/18639	0.211428571428571	1.1060390521631	0.273851257919546	0.700953892867146
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/3563	28/18639	0.25	1.30781644681448	0.279003760134452	0.712771602186096
GO:0004896	cytokine receptor activity	21/3563	96/18639	0.21875	1.14433939096267	0.281913338545476	0.71807337448677
GO:0000149	SNARE binding	23/3563	106/18639	0.216981132075472	1.13508597270691	0.283850551505356	0.71807337448677
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0008381	mechanosensitive monoatomic ion channel activity	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0031420	alkali metal ion binding	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0043395	heparan sulfate proteoglycan binding	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0046527	glucosyltransferase activity	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0046624	sphingolipid transporter activity	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0050145	nucleoside monophosphate kinase activity	5/3563	19/18639	0.263157894736842	1.37664889138367	0.290932930799304	0.71807337448677
GO:0008173	RNA methyltransferase activity	15/3563	67/18639	0.223880597014925	1.17117890759506	0.291358717271505	0.71807337448677
GO:0004090	carbonyl reductase (NADPH) activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0005031	tumor necrosis factor receptor activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0005345	purine nucleobase transmembrane transporter activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0015203	polyamine transmembrane transporter activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0015279	store-operated calcium channel activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0016427	tRNA (cytidine) methyltransferase activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0019911	structural constituent of myelin sheath	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0031996	thioesterase binding	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0035374	chondroitin sulfate binding	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0047429	nucleoside triphosphate diphosphatase activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0070097	delta-catenin binding	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0097177	mitochondrial ribosome binding	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0140135	mechanosensitive monoatomic cation channel activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0140999	histone H3K4 trimethyltransferase activity	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:1905394	retromer complex binding	3/3563	10/18639	0.3	1.56937973617738	0.295645536603118	0.71807337448677
GO:0005543	phospholipid binding	100/3563	497/18639	0.201207243460765	1.05256856886477	0.298810725496975	0.724439117734924
GO:0043022	ribosome binding	24/3563	112/18639	0.214285714285714	1.12098552584098	0.300880905195393	0.727629344787387
GO:0030552	cAMP binding	6/3563	24/18639	0.25	1.30781644681448	0.30340667645154	0.727629344787387
GO:0043998	histone H2A acetyltransferase activity	6/3563	24/18639	0.25	1.30781644681448	0.30340667645154	0.727629344787387
GO:0048027	mRNA 5'-UTR binding	6/3563	24/18639	0.25	1.30781644681448	0.30340667645154	0.727629344787387
GO:0070840	dynein complex binding	6/3563	24/18639	0.25	1.30781644681448	0.30340667645154	0.727629344787387
GO:0140033	acetylation-dependent protein binding	6/3563	24/18639	0.25	1.30781644681448	0.30340667645154	0.727629344787387
GO:0016860	intramolecular oxidoreductase activity	12/3563	53/18639	0.226415094339623	1.18443753673764	0.306439545013971	0.733580997146755
GO:0005507	copper ion binding	14/3563	63/18639	0.222222222222222	1.16250350827954	0.311040326579269	0.741660709877963
GO:0003785	actin monomer binding	7/3563	29/18639	0.241379310344828	1.26271932795881	0.312043574403951	0.741660709877963
GO:0035250	UDP-galactosyltransferase activity	7/3563	29/18639	0.241379310344828	1.26271932795881	0.312043574403951	0.741660709877963
GO:0051861	glycolipid binding	7/3563	29/18639	0.241379310344828	1.26271932795881	0.312043574403951	0.741660709877963
GO:0030165	PDZ domain binding	18/3563	83/18639	0.216867469879518	1.13449137554991	0.315834952927532	0.747173403742237
GO:0008175	tRNA methyltransferase activity	8/3563	34/18639	0.235294117647059	1.2308860675901	0.318270136921592	0.747173403742237
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	8/3563	34/18639	0.235294117647059	1.2308860675901	0.318270136921592	0.747173403742237
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/3563	34/18639	0.235294117647059	1.2308860675901	0.318270136921592	0.747173403742237
GO:0090482	vitamin transmembrane transporter activity	8/3563	34/18639	0.235294117647059	1.2308860675901	0.318270136921592	0.747173403742237
GO:0031005	filamin binding	4/3563	15/18639	0.266666666666667	1.39500420993545	0.318853864256642	0.747173403742237
GO:0050780	dopamine receptor binding	4/3563	15/18639	0.266666666666667	1.39500420993545	0.318853864256642	0.747173403742237
GO:0051371	muscle alpha-actinin binding	4/3563	15/18639	0.266666666666667	1.39500420993545	0.318853864256642	0.747173403742237
GO:0005126	cytokine receptor binding	56/3563	275/18639	0.203636363636364	1.06527594213252	0.320942852988806	0.750746814284888
GO:0035254	glutamate receptor binding	11/3563	49/18639	0.224489795918367	1.17436578897627	0.328967753896697	0.767171954375176
GO:0030295	protein kinase activator activity	29/3563	139/18639	0.20863309352518	1.09141516424806	0.331572237126332	0.767171954375176
GO:0016004	phospholipase activator activity	5/3563	20/18639	0.25	1.30781644681448	0.331999283035388	0.767171954375176
GO:0016505	peptidase activator activity involved in apoptotic process	5/3563	20/18639	0.25	1.30781644681448	0.331999283035388	0.767171954375176
GO:0030742	GTP-dependent protein binding	5/3563	20/18639	0.25	1.30781644681448	0.331999283035388	0.767171954375176
GO:0031418	L-ascorbic acid binding	5/3563	20/18639	0.25	1.30781644681448	0.331999283035388	0.767171954375176
GO:0140939	histone H4 methyltransferase activity	5/3563	20/18639	0.25	1.30781644681448	0.331999283035388	0.767171954375176
GO:0016853	isomerase activity	37/3563	180/18639	0.205555555555556	1.07531574515857	0.339292847976385	0.776560450886789
GO:0001965	G-protein alpha-subunit binding	7/3563	30/18639	0.233333333333333	1.22062868369352	0.345742286074578	0.776560450886789
GO:0001968	fibronectin binding	7/3563	30/18639	0.233333333333333	1.22062868369352	0.345742286074578	0.776560450886789
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/3563	30/18639	0.233333333333333	1.22062868369352	0.345742286074578	0.776560450886789
GO:0033612	receptor serine/threonine kinase binding	7/3563	30/18639	0.233333333333333	1.22062868369352	0.345742286074578	0.776560450886789
GO:0005343	organic acid:sodium symporter activity	8/3563	35/18639	0.228571428571429	1.19571789423038	0.349498683815603	0.776560450886789
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/3563	40/18639	0.225	1.17703480213303	0.352101308651185	0.776560450886789
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0000099	sulfur amino acid transmembrane transporter activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0003953	NAD+ nucleosidase activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0015173	aromatic amino acid transmembrane transporter activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0015205	nucleobase transmembrane transporter activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0019107	myristoyltransferase activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0019206	nucleoside kinase activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0032794	GTPase activating protein binding	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0034056	estrogen response element binding	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0034511	U3 snoRNA binding	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0042608	T cell receptor binding	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0043522	leucine zipper domain binding	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0070697	activin receptor binding	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0097493	structural molecule activity conferring elasticity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0140031	phosphorylation-dependent protein binding	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0180030	inositol phosphate kinase activity	3/3563	11/18639	0.272727272727273	1.42670885107034	0.35324382674594	0.776560450886789
GO:0004715	non-membrane spanning protein tyrosine kinase activity	10/3563	45/18639	0.222222222222222	1.16250350827954	0.353896229235737	0.776560450886789
GO:0042605	peptide antigen binding	10/3563	45/18639	0.222222222222222	1.16250350827954	0.353896229235737	0.776560450886789
GO:0005006	epidermal growth factor receptor activity	11/3563	50/18639	0.22	1.15087847319674	0.355104580170161	0.776560450886789
GO:0005017	platelet-derived growth factor receptor activity	11/3563	50/18639	0.22	1.15087847319674	0.355104580170161	0.776560450886789
GO:0005019	platelet-derived growth factor beta-receptor activity	11/3563	50/18639	0.22	1.15087847319674	0.355104580170161	0.776560450886789
GO:0032813	tumor necrosis factor receptor superfamily binding	11/3563	50/18639	0.22	1.15087847319674	0.355104580170161	0.776560450886789
GO:0048020	CCR chemokine receptor binding	11/3563	50/18639	0.22	1.15087847319674	0.355104580170161	0.776560450886789
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/3563	60/18639	0.216666666666667	1.13344092057255	0.356309232302875	0.776560450886789
GO:0019843	rRNA binding	14/3563	65/18639	0.215384615384615	1.12673416956325	0.356482671293635	0.776560450886789
GO:0038024	cargo receptor activity	14/3563	65/18639	0.215384615384615	1.12673416956325	0.356482671293635	0.776560450886789
GO:0008234	cysteine-type peptidase activity	38/3563	187/18639	0.203208556149733	1.06303796746418	0.36526499603145	0.790637793997046
GO:0004708	MAP kinase kinase activity	4/3563	16/18639	0.25	1.30781644681448	0.366509029974589	0.790637793997046
GO:0008142	oxysterol binding	4/3563	16/18639	0.25	1.30781644681448	0.366509029974589	0.790637793997046
GO:0015385	sodium:proton antiporter activity	4/3563	16/18639	0.25	1.30781644681448	0.366509029974589	0.790637793997046
GO:0022858	alanine transmembrane transporter activity	4/3563	16/18639	0.25	1.30781644681448	0.366509029974589	0.790637793997046
GO:0097027	ubiquitin-protein transferase activator activity	4/3563	16/18639	0.25	1.30781644681448	0.366509029974589	0.790637793997046
GO:0140104	molecular carrier activity	50/3563	249/18639	0.200803212851406	1.05045497736103	0.37329540411634	0.799290641462596
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/3563	21/18639	0.238095238095238	1.24553947315665	0.373522749053144	0.799290641462596
GO:0005123	death receptor binding	5/3563	21/18639	0.238095238095238	1.24553947315665	0.373522749053144	0.799290641462596
GO:0035613	RNA stem-loop binding	5/3563	21/18639	0.238095238095238	1.24553947315665	0.373522749053144	0.799290641462596
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/3563	21/18639	0.238095238095238	1.24553947315665	0.373522749053144	0.799290641462596
GO:0015216	purine nucleotide transmembrane transporter activity	6/3563	26/18639	0.230769230769231	1.20721518167491	0.377516000716987	0.80524646947806
GO:0051139	metal cation:proton antiporter activity	6/3563	26/18639	0.230769230769231	1.20721518167491	0.377516000716987	0.80524646947806
GO:0008235	metalloexopeptidase activity	14/3563	66/18639	0.212121212121212	1.10966243972138	0.379629938063562	0.806276713671975
GO:0017147	Wnt-protein binding	7/3563	31/18639	0.225806451612903	1.18125356486469	0.379816303134732	0.806276713671975
GO:0070273	phosphatidylinositol-4-phosphate binding	7/3563	31/18639	0.225806451612903	1.18125356486469	0.379816303134732	0.806276713671975
GO:0004033	aldo-keto reductase (NADPH) activity	8/3563	36/18639	0.222222222222222	1.16250350827954	0.381075119139187	0.807345257548318
GO:0005048	signal sequence binding	11/3563	51/18639	0.215686274509804	1.12831222862426	0.381532807661827	0.807345257548318
GO:0004519	endonuclease activity	26/3563	127/18639	0.204724409448819	1.07096779896619	0.38285690791985	0.808861181652891
GO:0005200	structural constituent of cytoskeleton	23/3563	112/18639	0.205357142857143	1.07427779559761	0.387648912085171	0.817687324857944
GO:0008238	exopeptidase activity	21/3563	102/18639	0.205882352941176	1.07702530914134	0.390937268265045	0.8233188355392
GO:0004857	enzyme inhibitor activity	82/3563	416/18639	0.197115384615385	1.03116296768065	0.397037432125269	0.824453068899304
GO:0016500	protein-hormone receptor activity	14/3563	67/18639	0.208955223880597	1.09310031375539	0.402946864310521	0.824453068899304
GO:0042054	histone methyltransferase activity	14/3563	67/18639	0.208955223880597	1.09310031375539	0.402946864310521	0.824453068899304
GO:0015932	nucleobase-containing compound transmembrane transporter activity	12/3563	57/18639	0.210526315789474	1.10131911310693	0.406421701206635	0.824453068899304
GO:0061733	protein-lysine-acetyltransferase activity	10/3563	47/18639	0.212765957446809	1.11303527388467	0.409778542543195	0.824453068899304
GO:0140359	ABC-type transporter activity	10/3563	47/18639	0.212765957446809	1.11303527388467	0.409778542543195	0.824453068899304
GO:0140938	histone H3 methyltransferase activity	10/3563	47/18639	0.212765957446809	1.11303527388467	0.409778542543195	0.824453068899304
GO:0004032	aldose reductase (NADPH) activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0004300	enoyl-CoA hydratase activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0010853	cyclase activator activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0015269	calcium-activated potassium channel activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0016423	tRNA (guanine) methyltransferase activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0017166	vinculin binding	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0034452	dynactin binding	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0035197	siRNA binding	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0035251	UDP-glucosyltransferase activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0035497	cAMP response element binding	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/3563	12/18639	0.25	1.30781644681448	0.410187981271937	0.824453068899304
GO:0004402	histone acetyltransferase activity	9/3563	42/18639	0.214285714285714	1.12098552584098	0.411348744008562	0.824453068899304
GO:0051879	Hsp90 protein binding	9/3563	42/18639	0.214285714285714	1.12098552584098	0.411348744008562	0.824453068899304
GO:0008170	N-methyltransferase activity	20/3563	98/18639	0.204081632653061	1.0676052627057	0.411943729804149	0.824453068899304
GO:0070851	growth factor receptor binding	28/3563	139/18639	0.201438848920863	1.05378015858433	0.412109824565494	0.824453068899304
GO:0023023	MHC protein complex binding	8/3563	37/18639	0.216216216216216	1.13108449454225	0.412782721277839	0.824453068899304
GO:0042805	actinin binding	8/3563	37/18639	0.216216216216216	1.13108449454225	0.412782721277839	0.824453068899304
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/3563	17/18639	0.235294117647059	1.2308860675901	0.413952590922807	0.824453068899304
GO:0004550	nucleoside diphosphate kinase activity	4/3563	17/18639	0.235294117647059	1.2308860675901	0.413952590922807	0.824453068899304
GO:0008429	phosphatidylethanolamine binding	4/3563	17/18639	0.235294117647059	1.2308860675901	0.413952590922807	0.824453068899304
GO:0015278	intracellularly gated calcium channel activity	4/3563	17/18639	0.235294117647059	1.2308860675901	0.413952590922807	0.824453068899304
GO:0016805	dipeptidase activity	4/3563	17/18639	0.235294117647059	1.2308860675901	0.413952590922807	0.824453068899304
GO:0031489	myosin V binding	4/3563	17/18639	0.235294117647059	1.2308860675901	0.413952590922807	0.824453068899304
GO:0046965	nuclear retinoid X receptor binding	4/3563	17/18639	0.235294117647059	1.2308860675901	0.413952590922807	0.824453068899304
GO:0051059	NF-kappaB binding	7/3563	32/18639	0.21875	1.14433939096267	0.413993743479687	0.824453068899304
GO:0008266	poly(U) RNA binding	6/3563	27/18639	0.222222222222222	1.16250350827954	0.414831380060274	0.824453068899304
GO:0046972	histone H4K16 acetyltransferase activity	5/3563	22/18639	0.227272727272727	1.18892404255862	0.41501394151956	0.824453068899304
GO:0050321	tau-protein kinase activity	5/3563	22/18639	0.227272727272727	1.18892404255862	0.41501394151956	0.824453068899304
GO:1901682	sulfur compound transmembrane transporter activity	13/3563	63/18639	0.206349206349206	1.07946754340243	0.429039822969379	0.851046206217948
GO:0015297	antiporter activity	27/3563	135/18639	0.2	1.04625315745159	0.430893855685204	0.853451967138402
GO:0005003	ephrin receptor activity	11/3563	53/18639	0.207547169811321	1.08573440867617	0.434756894509184	0.856008027502549
GO:0005005	transmembrane-ephrin receptor activity	11/3563	53/18639	0.207547169811321	1.08573440867617	0.434756894509184	0.856008027502549
GO:0005246	calcium channel regulator activity	11/3563	53/18639	0.207547169811321	1.08573440867617	0.434756894509184	0.856008027502549
GO:0038064	collagen receptor activity	11/3563	53/18639	0.207547169811321	1.08573440867617	0.434756894509184	0.856008027502549
GO:0008200	ion channel inhibitor activity	9/3563	43/18639	0.209302325581395	1.09491609500747	0.441023260092576	0.857364308639428
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/3563	43/18639	0.209302325581395	1.09491609500747	0.441023260092576	0.857364308639428
GO:0046982	protein heterodimerization activity	72/3563	369/18639	0.195121951219512	1.02073478775764	0.44366025376982	0.857364308639428
GO:0043531	ADP binding	8/3563	38/18639	0.210526315789474	1.10131911310693	0.444415267432501	0.857364308639428
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	33/3563	167/18639	0.197604790419162	1.03372317951803	0.446824249170418	0.857364308639428
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/3563	33/18639	0.212121212121212	1.10966243972138	0.448019294137259	0.857364308639428
GO:0140597	protein carrier chaperone	37/3563	188/18639	0.196808510638298	1.02955762834332	0.450894793615355	0.857364308639428
GO:0046966	nuclear thyroid hormone receptor binding	6/3563	28/18639	0.214285714285714	1.12098552584098	0.451875276403681	0.857364308639428
GO:0051393	alpha-actinin binding	6/3563	28/18639	0.214285714285714	1.12098552584098	0.451875276403681	0.857364308639428
GO:0051959	dynein light intermediate chain binding	6/3563	28/18639	0.214285714285714	1.12098552584098	0.451875276403681	0.857364308639428
GO:0004602	glutathione peroxidase activity	5/3563	23/18639	0.217391304347826	1.13723169288216	0.456033645976473	0.857364308639428
GO:0005158	insulin receptor binding	5/3563	23/18639	0.217391304347826	1.13723169288216	0.456033645976473	0.857364308639428
GO:0005283	amino acid:sodium symporter activity	5/3563	23/18639	0.217391304347826	1.13723169288216	0.456033645976473	0.857364308639428
GO:0140103	catalytic activity, acting on a glycoprotein	5/3563	23/18639	0.217391304347826	1.13723169288216	0.456033645976473	0.857364308639428
GO:0008525	phosphatidylcholine transporter activity	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:0015172	acidic amino acid transmembrane transporter activity	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:0017075	syntaxin-1 binding	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:0070064	proline-rich region binding	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:0099602	neurotransmitter receptor regulator activity	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:1901611	phosphatidylglycerol binding	4/3563	18/18639	0.222222222222222	1.16250350827954	0.460552312049779	0.857364308639428
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0005172	vascular endothelial growth factor receptor binding	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0008253	5'-nucleotidase activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0008417	fucosyltransferase activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0009982	pseudouridine synthase activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0015651	quaternary ammonium group transmembrane transporter activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0017154	semaphorin receptor activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0019104	DNA N-glycosylase activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0035673	oligopeptide transmembrane transporter activity	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0051011	microtubule minus-end binding	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0089720	caspase binding	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0097157	pre-mRNA intronic binding	3/3563	13/18639	0.230769230769231	1.20721518167491	0.465461138060031	0.857364308639428
GO:0005004	GPI-linked ephrin receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0005008	hepatocyte growth factor receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0005009	insulin receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0005011	macrophage colony-stimulating factor receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0005018	platelet-derived growth factor alpha-receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0005020	stem cell factor receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0008288	boss receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0016763	pentosyltransferase activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0036332	placental growth factor receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0038062	protein tyrosine kinase collagen receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0060175	brain-derived neurotrophic factor receptor activity	10/3563	49/18639	0.204081632653061	1.0676052627057	0.465720807773333	0.857364308639428
GO:0044183	protein folding chaperone	15/3563	75/18639	0.2	1.04625315745159	0.468845520031794	0.861924567903755
GO:0016248	channel inhibitor activity	9/3563	44/18639	0.204545454545455	1.07003163830276	0.470512943050871	0.863796865104426
GO:0035091	phosphatidylinositol binding	55/3563	284/18639	0.193661971830986	1.01309724753235	0.481145840718026	0.88048827424891
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/3563	34/18639	0.205882352941176	1.07702530914134	0.481657964526505	0.88048827424891
GO:0030332	cyclin binding	7/3563	34/18639	0.205882352941176	1.07702530914134	0.481657964526505	0.88048827424891
GO:1901981	phosphatidylinositol phosphate binding	36/3563	185/18639	0.194594594594595	1.01797604508803	0.482250903025887	0.88048827424891
GO:0015101	organic cation transmembrane transporter activity	16/3563	81/18639	0.197530864197531	1.03333645180404	0.486544807845691	0.887111149647418
GO:0031490	chromatin DNA binding	25/3563	128/18639	0.1953125	1.02173159907381	0.487960743393897	0.888475717451816
GO:0005007	fibroblast growth factor receptor activity	10/3563	50/18639	0.2	1.04625315745159	0.493374864674127	0.897106482078227
GO:0004622	lysophospholipase activity	5/3563	24/18639	0.208333333333333	1.08984703901207	0.496198637956719	0.897337482500533
GO:0005315	phosphate transmembrane transporter activity	5/3563	24/18639	0.208333333333333	1.08984703901207	0.496198637956719	0.897337482500533
GO:0035035	histone acetyltransferase binding	5/3563	24/18639	0.208333333333333	1.08984703901207	0.496198637956719	0.897337482500533
GO:0060229	lipase activator activity	5/3563	24/18639	0.208333333333333	1.08984703901207	0.496198637956719	0.897337482500533
GO:0140767	enzyme-substrate adaptor activity	27/3563	139/18639	0.194244604316547	1.0161451529206	0.497322281863789	0.898149195604753
GO:0008009	chemokine activity	9/3563	45/18639	0.2	1.04625315745159	0.499667121504654	0.898725592868507
GO:0051539	4 iron, 4 sulfur cluster binding	9/3563	45/18639	0.2	1.04625315745159	0.499667121504654	0.898725592868507
GO:0141110	transporter inhibitor activity	9/3563	45/18639	0.2	1.04625315745159	0.499667121504654	0.898725592868507
GO:0004843	cysteine-type deubiquitinase activity	21/3563	108/18639	0.194444444444444	1.0171905697446	0.504167799036994	0.899222895880291
GO:0003756	protein disulfide isomerase activity	4/3563	19/18639	0.210526315789474	1.10131911310693	0.505784147049907	0.899222895880291
GO:0005229	intracellularly calcium-gated chloride channel activity	4/3563	19/18639	0.210526315789474	1.10131911310693	0.505784147049907	0.899222895880291
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/3563	19/18639	0.210526315789474	1.10131911310693	0.505784147049907	0.899222895880291
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/3563	19/18639	0.210526315789474	1.10131911310693	0.505784147049907	0.899222895880291
GO:0042577	lipid phosphatase activity	4/3563	19/18639	0.210526315789474	1.10131911310693	0.505784147049907	0.899222895880291
GO:0120227	acyl-CoA binding	4/3563	19/18639	0.210526315789474	1.10131911310693	0.505784147049907	0.899222895880291
GO:0141147	intracellularly calcium-gated channel activity	4/3563	19/18639	0.210526315789474	1.10131911310693	0.505784147049907	0.899222895880291
GO:0071949	FAD binding	8/3563	40/18639	0.2	1.04625315745159	0.506699603238331	0.899222895880291
GO:0140662	ATP-dependent protein folding chaperone	8/3563	40/18639	0.2	1.04625315745159	0.506699603238331	0.899222895880291
GO:0019212	phosphatase inhibitor activity	11/3563	56/18639	0.196428571428571	1.02757006535424	0.513726102099849	0.907704810031194
GO:0016229	steroid dehydrogenase activity	7/3563	35/18639	0.2	1.04625315745159	0.514697784704231	0.907704810031194
GO:0005313	L-glutamate transmembrane transporter activity	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:0008191	metalloendopeptidase inhibitor activity	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:0008195	phosphatidate phosphatase activity	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:0015386	potassium:proton antiporter activity	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:0031404	chloride ion binding	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:0032036	myosin heavy chain binding	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:1901474	azole transmembrane transporter activity	3/3563	14/18639	0.214285714285714	1.12098552584098	0.518298764555753	0.907704810031194
GO:0005021	vascular endothelial growth factor receptor activity	10/3563	51/18639	0.196078431372549	1.02573838965842	0.520653415164931	0.909435296042681
GO:0005030	neurotrophin receptor activity	10/3563	51/18639	0.196078431372549	1.02573838965842	0.520653415164931	0.909435296042681
GO:0015215	nucleotide transmembrane transporter activity	6/3563	30/18639	0.2	1.04625315745159	0.524005818116303	0.912894952765445
GO:0016769	transferase activity, transferring nitrogenous groups	6/3563	30/18639	0.2	1.04625315745159	0.524005818116303	0.912894952765445
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/3563	46/18639	0.195652173913043	1.02350852359394	0.528347614162153	0.919255783594543
GO:0015179	L-amino acid transmembrane transporter activity	12/3563	62/18639	0.193548387096774	1.01250305559831	0.53207266248184	0.923470477051915
GO:0000030	mannosyltransferase activity	5/3563	25/18639	0.2	1.04625315745159	0.535184248544732	0.923470477051915
GO:0017056	structural constituent of nuclear pore	5/3563	25/18639	0.2	1.04625315745159	0.535184248544732	0.923470477051915
GO:0042974	nuclear retinoic acid receptor binding	5/3563	25/18639	0.2	1.04625315745159	0.535184248544732	0.923470477051915
GO:0001727	lipid kinase activity	8/3563	41/18639	0.195121951219512	1.02073478775764	0.537014387106072	0.923470477051915
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	8/3563	41/18639	0.195121951219512	1.02073478775764	0.537014387106072	0.923470477051915
GO:0017080	sodium channel regulator activity	8/3563	41/18639	0.195121951219512	1.02073478775764	0.537014387106072	0.923470477051915
GO:0042169	SH2 domain binding	8/3563	41/18639	0.195121951219512	1.02073478775764	0.537014387106072	0.923470477051915
GO:0140828	metal cation:monoatomic cation antiporter activity	8/3563	41/18639	0.195121951219512	1.02073478775764	0.537014387106072	0.923470477051915
GO:0016410	N-acyltransferase activity	18/3563	94/18639	0.191489361702128	1.0017317464962	0.538437046412774	0.924722204871487
GO:0030145	manganese ion binding	13/3563	68/18639	0.191176470588235	1.00009492991696	0.548781008970193	0.937212324646481
GO:0000339	RNA cap binding	4/3563	20/18639	0.2	1.04625315745159	0.549230363053535	0.937212324646481
GO:0001972	retinoic acid binding	4/3563	20/18639	0.2	1.04625315745159	0.549230363053535	0.937212324646481
GO:0010851	cyclase regulator activity	4/3563	20/18639	0.2	1.04625315745159	0.549230363053535	0.937212324646481
GO:0042288	MHC class I protein binding	4/3563	20/18639	0.2	1.04625315745159	0.549230363053535	0.937212324646481
GO:0005164	tumor necrosis factor receptor binding	6/3563	31/18639	0.193548387096774	1.01250305559831	0.55861130171188	0.95199954235405
GO:0019783	ubiquitin-like protein peptidase activity	24/3563	127/18639	0.188976377952756	0.988585660584176	0.560937239117864	0.952419327705587
GO:0017116	single-stranded DNA helicase activity	11/3563	58/18639	0.189655172413793	0.992136614824779	0.564556585881368	0.952419327705587
GO:0061980	regulatory RNA binding	11/3563	58/18639	0.189655172413793	0.992136614824779	0.564556585881368	0.952419327705587
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	23/3563	122/18639	0.188524590163934	0.986222238581413	0.566208003418977	0.952419327705587
GO:0019894	kinesin binding	8/3563	42/18639	0.19047619047619	0.99643157852532	0.566582773717252	0.952419327705587
GO:0035198	miRNA binding	8/3563	42/18639	0.19047619047619	0.99643157852532	0.566582773717252	0.952419327705587
GO:0048487	beta-tubulin binding	8/3563	42/18639	0.19047619047619	0.99643157852532	0.566582773717252	0.952419327705587
GO:0004559	alpha-mannosidase activity	3/3563	15/18639	0.2	1.04625315745159	0.56815998963053	0.952419327705587
GO:0005523	tropomyosin binding	3/3563	15/18639	0.2	1.04625315745159	0.56815998963053	0.952419327705587
GO:0008252	nucleotidase activity	3/3563	15/18639	0.2	1.04625315745159	0.56815998963053	0.952419327705587
GO:0045504	dynein heavy chain binding	3/3563	15/18639	0.2	1.04625315745159	0.56815998963053	0.952419327705587
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/3563	15/18639	0.2	1.04625315745159	0.56815998963053	0.952419327705587
GO:0140161	monocarboxylate:sodium symporter activity	3/3563	15/18639	0.2	1.04625315745159	0.56815998963053	0.952419327705587
GO:0140098	catalytic activity, acting on RNA	73/3563	387/18639	0.188630490956072	0.986776233772167	0.571664748499563	0.952710301911452
GO:0016279	protein-lysine N-methyltransferase activity	13/3563	69/18639	0.188405797101449	0.985600800497871	0.5717697317601	0.952710301911452
GO:0008198	ferrous iron binding	5/3563	26/18639	0.192307692307692	1.00601265139576	0.572724307551338	0.952710301911452
GO:0043548	phosphatidylinositol 3-kinase binding	5/3563	26/18639	0.192307692307692	1.00601265139576	0.572724307551338	0.952710301911452
GO:0120014	phospholipid transfer activity	5/3563	26/18639	0.192307692307692	1.00601265139576	0.572724307551338	0.952710301911452
GO:0004864	protein phosphatase inhibitor activity	10/3563	53/18639	0.188679245283019	0.987031280614704	0.5736526416696	0.952710301911452
GO:0015291	secondary active transmembrane transporter activity	54/3563	287/18639	0.18815331010453	0.984279973909157	0.575942308624108	0.952710301911452
GO:0030551	cyclic nucleotide binding	7/3563	37/18639	0.189189189189189	0.989698932724473	0.578257587298373	0.952710301911452
GO:0015174	basic amino acid transmembrane transporter activity	4/3563	21/18639	0.19047619047619	0.99643157852532	0.590573331053628	0.952710301911452
GO:0070182	DNA polymerase binding	4/3563	21/18639	0.19047619047619	0.99643157852532	0.590573331053628	0.952710301911452
GO:0050660	flavin adenine dinucleotide binding	16/3563	86/18639	0.186046511627907	0.973258751117754	0.591510727875319	0.952710301911452
GO:0015106	bicarbonate transmembrane transporter activity	6/3563	32/18639	0.1875	0.980862335110862	0.591984584380848	0.952710301911452
GO:0031369	translation initiation factor binding	6/3563	32/18639	0.1875	0.980862335110862	0.591984584380848	0.952710301911452
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/3563	32/18639	0.1875	0.980862335110862	0.591984584380848	0.952710301911452
GO:0043425	bHLH transcription factor binding	6/3563	32/18639	0.1875	0.980862335110862	0.591984584380848	0.952710301911452
GO:0016278	lysine N-methyltransferase activity	13/3563	70/18639	0.185714285714286	0.971520789062187	0.594278260442473	0.952710301911452
GO:0000182	rDNA binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0005131	growth hormone receptor binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0005522	profilin binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0008140	cAMP response element binding protein binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0008239	dipeptidyl-peptidase activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0008519	ammonium channel activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0015643	toxic substance binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0016783	sulfurtransferase activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0016868	intramolecular phosphotransferase activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0030957	Tat protein binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0042975	peroxisome proliferator activated receptor binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0043121	neurotrophin binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0045322	unmethylated CpG binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0050308	sugar-phosphatase activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0070513	death domain binding	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:1990757	ubiquitin ligase activator activity	2/3563	10/18639	0.2	1.04625315745159	0.596964982565102	0.952710301911452
GO:0008168	methyltransferase activity	38/3563	204/18639	0.186274509803922	0.974451470175496	0.599060076683096	0.954908936605031
GO:0140034	methylation-dependent protein binding	14/3563	76/18639	0.184210526315789	0.963654223968566	0.607387458223442	0.958649306410505
GO:0005253	monoatomic anion channel activity	19/3563	103/18639	0.184466019417476	0.964990776290298	0.608329871416917	0.958649306410505
GO:0005501	retinoid binding	7/3563	38/18639	0.184210526315789	0.963654223968566	0.608480046622925	0.958649306410505
GO:0019840	isoprenoid binding	7/3563	38/18639	0.184210526315789	0.963654223968566	0.608480046622925	0.958649306410505
GO:0004364	glutathione transferase activity	5/3563	27/18639	0.185185185185185	0.968752923566283	0.608609063799306	0.958649306410505
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/3563	27/18639	0.185185185185185	0.968752923566283	0.608609063799306	0.958649306410505
GO:0005044	scavenger receptor activity	5/3563	27/18639	0.185185185185185	0.968752923566283	0.608609063799306	0.958649306410505
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/3563	27/18639	0.185185185185185	0.968752923566283	0.608609063799306	0.958649306410505
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	5/3563	27/18639	0.185185185185185	0.968752923566283	0.608609063799306	0.958649306410505
GO:0035255	ionotropic glutamate receptor binding	5/3563	27/18639	0.185185185185185	0.968752923566283	0.608609063799306	0.958649306410505
GO:0000062	fatty-acyl-CoA binding	3/3563	16/18639	0.1875	0.980862335110862	0.614694826474209	0.960280298165695
GO:0003688	DNA replication origin binding	3/3563	16/18639	0.1875	0.980862335110862	0.614694826474209	0.960280298165695
GO:0005149	interleukin-1 receptor binding	3/3563	16/18639	0.1875	0.980862335110862	0.614694826474209	0.960280298165695
GO:0015923	mannosidase activity	3/3563	16/18639	0.1875	0.980862335110862	0.614694826474209	0.960280298165695
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/3563	16/18639	0.1875	0.980862335110862	0.614694826474209	0.960280298165695
GO:0019841	retinol binding	3/3563	16/18639	0.1875	0.980862335110862	0.614694826474209	0.960280298165695
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/3563	16/18639	0.1875	0.980862335110862	0.614694826474209	0.960280298165695
GO:0016779	nucleotidyltransferase activity	25/3563	136/18639	0.183823529411765	0.961629740304766	0.620774417688319	0.968640972969698
GO:0019956	chemokine binding	6/3563	33/18639	0.181818181818182	0.951139234046896	0.623976871101646	0.972497910346944
GO:0015377	chloride:monoatomic cation symporter activity	4/3563	22/18639	0.181818181818182	0.951139234046896	0.629586528727865	0.973467800349702
GO:0016881	acid-amino acid ligase activity	4/3563	22/18639	0.181818181818182	0.951139234046896	0.629586528727865	0.973467800349702
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/3563	22/18639	0.181818181818182	0.951139234046896	0.629586528727865	0.973467800349702
GO:0031683	G-protein beta/gamma-subunit complex binding	4/3563	22/18639	0.181818181818182	0.951139234046896	0.629586528727865	0.973467800349702
GO:0140035	ubiquitin-like protein reader activity	4/3563	22/18639	0.181818181818182	0.951139234046896	0.629586528727865	0.973467800349702
GO:0140517	protein-RNA adaptor activity	4/3563	22/18639	0.181818181818182	0.951139234046896	0.629586528727865	0.973467800349702
GO:0101005	deubiquitinase activity	21/3563	115/18639	0.182608695652174	0.955274622021013	0.629718840045901	0.973467800349702
GO:0019905	syntaxin binding	11/3563	61/18639	0.180327868852459	0.943343010817004	0.636368709758594	0.981152078863797
GO:0000217	DNA secondary structure binding	7/3563	39/18639	0.179487179487179	0.938945141302705	0.637508194001493	0.981152078863797
GO:0042379	chemokine receptor binding	13/3563	72/18639	0.180555555555556	0.944534100477126	0.637635938803543	0.981152078863797
GO:0005516	calmodulin binding	38/3563	207/18639	0.183574879227053	0.960328985100489	0.63763827814965	0.981152078863797
GO:0016866	intramolecular transferase activity	5/3563	28/18639	0.178571428571429	0.934154604867487	0.642681626276616	0.982506585143271
GO:0046625	sphingolipid binding	5/3563	28/18639	0.178571428571429	0.934154604867487	0.642681626276616	0.982506585143271
GO:0002162	dystroglycan binding	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0004016	adenylate cyclase activity	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0008172	S-methyltransferase activity	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0008271	secondary active sulfate transmembrane transporter activity	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0019203	carbohydrate phosphatase activity	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0032404	mismatch repair complex binding	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0047676	arachidonate-CoA ligase activity	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0048407	platelet-derived growth factor binding	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0050998	nitric-oxide synthase binding	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0070990	snRNP binding	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:1990948	ubiquitin ligase inhibitor activity	2/3563	11/18639	0.181818181818182	0.951139234046896	0.651125239413804	0.982506585143271
GO:0008509	monoatomic anion transmembrane transporter activity	27/3563	149/18639	0.181208053691275	0.947947491650766	0.654224397155206	0.982506585143271
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0030169	low-density lipoprotein particle binding	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0030548	acetylcholine receptor regulator activity	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0036041	long-chain fatty acid binding	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0070402	NADPH binding	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0070403	NAD+ binding	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0070492	oligosaccharide binding	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:1901567	fatty acid derivative binding	3/3563	17/18639	0.176470588235294	0.923164550692576	0.657711019806652	0.982506585143271
GO:0008276	protein methyltransferase activity	17/3563	95/18639	0.178947368421053	0.936121246140893	0.659791894003878	0.984510101927312
GO:0008171	O-methyltransferase activity	4/3563	23/18639	0.173913043478261	0.909785354305727	0.666123977728159	0.991734915387225
GO:0031681	G-protein beta-subunit binding	4/3563	23/18639	0.173913043478261	0.909785354305727	0.666123977728159	0.991734915387225
GO:0015370	solute:sodium symporter activity	14/3563	79/18639	0.177215189873418	0.927059759767228	0.668292841716089	0.993852259580017
GO:0016741	transferase activity, transferring one-carbon groups	39/3563	215/18639	0.181395348837209	0.94892728233981	0.669736647095041	0.994887809468191
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/3563	29/18639	0.172413793103448	0.901942377113436	0.674833400145087	0.998003617325678
GO:0005416	amino acid:monoatomic cation symporter activity	5/3563	29/18639	0.172413793103448	0.901942377113436	0.674833400145087	0.998003617325678
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/3563	29/18639	0.172413793103448	0.901942377113436	0.674833400145087	0.998003617325678
GO:0097472	cyclin-dependent protein kinase activity	5/3563	29/18639	0.172413793103448	0.901942377113436	0.674833400145087	0.998003617325678
GO:0035064	methylated histone binding	13/3563	74/18639	0.175675675675676	0.919006151815582	0.678481786782271	1
GO:0048029	monosaccharide binding	13/3563	74/18639	0.175675675675676	0.919006151815582	0.678481786782271	1
GO:0001664	G protein-coupled receptor binding	54/3563	297/18639	0.181818181818182	0.951139234046896	0.682797875940138	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	23/3563	130/18639	0.176923076923077	0.925531639284095	0.69469939121161	1
GO:0016209	antioxidant activity	15/3563	86/18639	0.174418604651163	0.912430079172895	0.695772845470416	1
GO:0003746	translation elongation factor activity	3/3563	18/18639	0.166666666666667	0.871877631209655	0.697142761358027	1
GO:0008409	5'-3' exonuclease activity	3/3563	18/18639	0.166666666666667	0.871877631209655	0.697142761358027	1
GO:0016854	racemase and epimerase activity	3/3563	18/18639	0.166666666666667	0.871877631209655	0.697142761358027	1
GO:0003720	telomerase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0003995	acyl-CoA dehydrogenase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0004000	adenosine deaminase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0005049	nuclear export signal receptor activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0005436	sodium:phosphate symporter activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0015132	prostaglandin transmembrane transporter activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0016208	AMP binding	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0016273	arginine N-methyltransferase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0016274	protein-arginine N-methyltransferase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0016840	carbon-nitrogen lyase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0031543	peptidyl-proline dioxygenase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:1990459	transferrin receptor binding	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:1990817	poly(A) RNA polymerase activity	2/3563	12/18639	0.166666666666667	0.871877631209655	0.699312691042178	1
GO:1990518	single-stranded 3'-5' DNA helicase activity	8/3563	47/18639	0.170212765957447	0.890428219107733	0.699587247206597	1
GO:0005540	hyaluronic acid binding	4/3563	24/18639	0.166666666666667	0.871877631209655	0.700109045682447	1
GO:0019957	C-C chemokine binding	4/3563	24/18639	0.166666666666667	0.871877631209655	0.700109045682447	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/3563	30/18639	0.166666666666667	0.871877631209655	0.704998916550843	1
GO:0070566	adenylyltransferase activity	5/3563	30/18639	0.166666666666667	0.871877631209655	0.704998916550843	1
GO:0005544	calcium-dependent phospholipid binding	9/3563	53/18639	0.169811320754717	0.888328152553233	0.707178231725781	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	10/3563	59/18639	0.169491525423729	0.88665521817931	0.714443946105481	1
GO:0036002	pre-mRNA binding	10/3563	59/18639	0.169491525423729	0.88665521817931	0.714443946105481	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	8/3563	48/18639	0.166666666666667	0.871877631209655	0.722744079117885	1
GO:0032266	phosphatidylinositol-3-phosphate binding	8/3563	48/18639	0.166666666666667	0.871877631209655	0.722744079117885	1
GO:0038187	pattern recognition receptor activity	8/3563	48/18639	0.166666666666667	0.871877631209655	0.722744079117885	1
GO:0043138	3'-5' DNA helicase activity	8/3563	48/18639	0.166666666666667	0.871877631209655	0.722744079117885	1
GO:0015103	inorganic anion transmembrane transporter activity	29/3563	165/18639	0.175757575757576	0.919434592912	0.722973685480921	1
GO:0042393	histone binding	44/3563	247/18639	0.178137651821862	0.931885403398173	0.724014194477537	1
GO:0030246	carbohydrate binding	50/3563	280/18639	0.178571428571429	0.934154604867487	0.727948617208671	1
GO:0140299	molecular sensor activity	12/3563	71/18639	0.169014084507042	0.88415759784641	0.72807488077157	1
GO:0050661	NADP binding	9/3563	54/18639	0.166666666666667	0.871877631209655	0.728776818508569	1
GO:0001848	complement binding	4/3563	25/18639	0.16	0.837002525961269	0.731523292756297	1
GO:0008483	transaminase activity	4/3563	25/18639	0.16	0.837002525961269	0.731523292756297	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/3563	25/18639	0.16	0.837002525961269	0.731523292756297	1
GO:0047617	fatty acyl-CoA hydrolase activity	4/3563	25/18639	0.16	0.837002525961269	0.731523292756297	1
GO:0015294	solute:monoatomic cation symporter activity	20/3563	116/18639	0.172413793103448	0.901942377113436	0.73190474403214	1
GO:1901681	sulfur compound binding	49/3563	275/18639	0.178181818181818	0.932116449365958	0.732072540851595	1
GO:0016918	retinal binding	3/3563	19/18639	0.157894736842105	0.825989334830199	0.7330225015408	1
GO:0022821	solute:potassium antiporter activity	3/3563	19/18639	0.157894736842105	0.825989334830199	0.7330225015408	1
GO:0034987	immunoglobulin receptor binding	3/3563	19/18639	0.157894736842105	0.825989334830199	0.7330225015408	1
GO:0042834	peptidoglycan binding	3/3563	19/18639	0.157894736842105	0.825989334830199	0.7330225015408	1
GO:0097001	ceramide binding	3/3563	19/18639	0.157894736842105	0.825989334830199	0.7330225015408	1
GO:0140036	ubiquitin-modified protein reader activity	3/3563	19/18639	0.157894736842105	0.825989334830199	0.7330225015408	1
GO:0005452	solute:inorganic anion antiporter activity	5/3563	31/18639	0.161290322580645	0.843752546331924	0.733150380942952	1
GO:0072349	modified amino acid transmembrane transporter activity	5/3563	31/18639	0.161290322580645	0.843752546331924	0.733150380942952	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	10/3563	60/18639	0.166666666666667	0.871877631209655	0.734709671353658	1
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	10/3563	60/18639	0.166666666666667	0.871877631209655	0.734709671353658	1
GO:1902936	phosphatidylinositol bisphosphate binding	19/3563	111/18639	0.171171171171171	0.895441891512618	0.740141552341486	1
GO:0008135	translation factor activity, RNA binding	14/3563	83/18639	0.168674698795181	0.882382180983265	0.740634639723936	1
GO:0003964	RNA-directed DNA polymerase activity	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0008035	high-density lipoprotein particle binding	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0031432	titin binding	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0046974	histone H3K9 methyltransferase activity	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0061459	L-arginine transmembrane transporter activity	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0071714	icosanoid transmembrane transporter activity	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0140666	annealing activity	2/3563	13/18639	0.153846153846154	0.804810121116605	0.74183115522075	1
GO:0140101	catalytic activity, acting on a tRNA	24/3563	139/18639	0.172661870503597	0.903240135929427	0.742910776867507	1
GO:0061135	endopeptidase regulator activity	32/3563	184/18639	0.173913043478261	0.909785354305727	0.752370242882407	1
GO:0180051	translation factor activity	14/3563	84/18639	0.166666666666667	0.871877631209655	0.757000358769106	1
GO:0071813	lipoprotein particle binding	5/3563	32/18639	0.15625	0.817385279259051	0.759292195121119	1
GO:0071814	protein-lipid complex binding	5/3563	32/18639	0.15625	0.817385279259051	0.759292195121119	1
GO:0042887	amide transmembrane transporter activity	6/3563	38/18639	0.157894736842105	0.825989334830199	0.760280038017003	1
GO:0005227	calcium-activated cation channel activity	4/3563	26/18639	0.153846153846154	0.804810121116605	0.760395835520835	1
GO:0016289	acyl-CoA hydrolase activity	4/3563	26/18639	0.153846153846154	0.804810121116605	0.760395835520835	1
GO:0030247	polysaccharide binding	4/3563	26/18639	0.153846153846154	0.804810121116605	0.760395835520835	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/3563	20/18639	0.15	0.784689868088689	0.76545640833267	1
GO:0044325	transmembrane transporter binding	23/3563	136/18639	0.169117647058824	0.884699361080385	0.775227883245282	1
GO:0072341	modified amino acid binding	15/3563	91/18639	0.164835164835165	0.862296558339219	0.777153219108062	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/3563	14/18639	0.142857142857143	0.74732368389399	0.779086553664917	1
GO:0030983	mismatched DNA binding	2/3563	14/18639	0.142857142857143	0.74732368389399	0.779086553664917	1
GO:0003678	DNA helicase activity	12/3563	74/18639	0.162162162162162	0.848313370906691	0.779870424302904	1
GO:0003684	damaged DNA binding	12/3563	74/18639	0.162162162162162	0.848313370906691	0.779870424302904	1
GO:0003743	translation initiation factor activity	8/3563	51/18639	0.156862745098039	0.820590711726734	0.784815447362716	1
GO:0061134	peptidase regulator activity	39/3563	226/18639	0.172566371681416	0.902740556208227	0.786427814634526	1
GO:0001671	ATPase activator activity	4/3563	27/18639	0.148148148148148	0.775002338853026	0.786793534950667	1
GO:0004601	peroxidase activity	9/3563	57/18639	0.157894736842105	0.825989334830199	0.78700250567582	1
GO:0052689	carboxylic ester hydrolase activity	15/3563	92/18639	0.16304347826087	0.852923769661619	0.791458258700742	1
GO:0009975	cyclase activity	3/3563	21/18639	0.142857142857143	0.74732368389399	0.794603587879177	1
GO:0019200	carbohydrate kinase activity	3/3563	21/18639	0.142857142857143	0.74732368389399	0.794603587879177	1
GO:0036122	BMP binding	3/3563	21/18639	0.142857142857143	0.74732368389399	0.794603587879177	1
GO:0051010	microtubule plus-end binding	3/3563	21/18639	0.142857142857143	0.74732368389399	0.794603587879177	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/3563	52/18639	0.153846153846154	0.804810121116605	0.803053878715249	1
GO:0032451	demethylase activity	6/3563	40/18639	0.15	0.784689868088689	0.803310436293956	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/3563	34/18639	0.147058823529412	0.769303792243813	0.805693898629471	1
GO:0016831	carboxy-lyase activity	5/3563	34/18639	0.147058823529412	0.769303792243813	0.805693898629471	1
GO:0019842	vitamin binding	25/3563	150/18639	0.166666666666667	0.871877631209655	0.806532688152512	1
GO:0050698	proteoglycan sulfotransferase activity	4/3563	28/18639	0.142857142857143	0.74732368389399	0.810812186396342	1
GO:0141052	histone H3 demethylase activity	4/3563	28/18639	0.142857142857143	0.74732368389399	0.810812186396342	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0004953	icosanoid receptor activity	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0010181	FMN binding	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0015116	sulfate transmembrane transporter activity	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0017081	chloride channel regulator activity	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0033130	acetylcholine receptor binding	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0034483	heparan sulfate sulfotransferase activity	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0047372	monoacylglycerol lipase activity	2/3563	15/18639	0.133333333333333	0.697502104967724	0.811536794285591	1
GO:0042562	hormone binding	15/3563	94/18639	0.159574468085106	0.834776455413499	0.818093198040433	1
GO:0005243	gap junction channel activity	3/3563	22/18639	0.136363636363636	0.713354425535172	0.820658913008331	1
GO:0033691	sialic acid binding	3/3563	22/18639	0.136363636363636	0.713354425535172	0.820658913008331	1
GO:0005504	fatty acid binding	7/3563	47/18639	0.148936170212766	0.779124691719266	0.820659187278211	1
GO:0061749	forked DNA-dependent helicase activity	7/3563	47/18639	0.148936170212766	0.779124691719266	0.820659187278211	1
GO:0008514	organic anion transmembrane transporter activity	46/3563	269/18639	0.171003717472119	0.894565896705817	0.821949953582259	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/3563	41/18639	0.146341463414634	0.765551090818233	0.822450845905915	1
GO:0042287	MHC protein binding	6/3563	41/18639	0.146341463414634	0.765551090818233	0.822450845905915	1
GO:0015293	symporter activity	24/3563	146/18639	0.164383561643836	0.859934102015002	0.823603685907371	1
GO:0043015	gamma-tubulin binding	5/3563	35/18639	0.142857142857143	0.74732368389399	0.826077389897339	1
GO:0046906	tetrapyrrole binding	25/3563	152/18639	0.164473684210526	0.860405557114791	0.826842321060778	1
GO:0140674	ATP-dependent histone chaperone activity	25/3563	152/18639	0.164473684210526	0.860405557114791	0.826842321060778	1
GO:0099604	ligand-gated calcium channel activity	4/3563	29/18639	0.137931034482759	0.721553901690749	0.832568792196542	1
GO:0106222	lncRNA binding	4/3563	29/18639	0.137931034482759	0.721553901690749	0.832568792196542	1
GO:0140713	histone chaperone activity	27/3563	164/18639	0.164634146341463	0.861244977170513	0.83311818900462	1
GO:0051287	NAD binding	8/3563	54/18639	0.148148148148148	0.775002338853026	0.835980458992474	1
GO:0140463	chromatin-protein adaptor activity	8/3563	54/18639	0.148148148148148	0.775002338853026	0.835980458992474	1
GO:0009378	four-way junction helicase activity	7/3563	48/18639	0.145833333333333	0.762892927308448	0.837376400866559	1
GO:0036121	double-stranded DNA helicase activity	7/3563	48/18639	0.145833333333333	0.762892927308448	0.837376400866559	1
GO:0140693	molecular condensate scaffold activity	7/3563	48/18639	0.145833333333333	0.762892927308448	0.837376400866559	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/3563	16/18639	0.125	0.653908223407241	0.839657075401503	1
GO:0015378	sodium:chloride symporter activity	2/3563	16/18639	0.125	0.653908223407241	0.839657075401503	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/3563	16/18639	0.125	0.653908223407241	0.839657075401503	1
GO:0017134	fibroblast growth factor binding	3/3563	23/18639	0.130434782608696	0.682339015729295	0.843839153300357	1
GO:0015171	amino acid transmembrane transporter activity	16/3563	102/18639	0.156862745098039	0.820590711726734	0.8439955490943	1
GO:0004190	aspartic-type endopeptidase activity	5/3563	36/18639	0.138888888888889	0.726564692674712	0.844689672959205	1
GO:0045505	dynein intermediate chain binding	5/3563	36/18639	0.138888888888889	0.726564692674712	0.844689672959205	1
GO:0003689	DNA clamp loader activity	26/3563	160/18639	0.1625	0.850080690429413	0.848181173450096	1
GO:0033293	monocarboxylic acid binding	12/3563	79/18639	0.151898734177215	0.794622651229053	0.849922549921868	1
GO:0022839	monoatomic ion-gated channel activity	4/3563	30/18639	0.133333333333333	0.697502104967724	0.852194926911265	1
GO:0031210	phosphatidylcholine binding	4/3563	30/18639	0.133333333333333	0.697502104967724	0.852194926911265	1
GO:0032452	histone demethylase activity	4/3563	30/18639	0.133333333333333	0.697502104967724	0.852194926911265	1
GO:0048019	receptor antagonist activity	4/3563	30/18639	0.133333333333333	0.697502104967724	0.852194926911265	1
GO:0043177	organic acid binding	31/3563	189/18639	0.164021164021164	0.858038303730136	0.8529255071633	1
GO:0008237	metallopeptidase activity	30/3563	184/18639	0.16304347826087	0.852923769661619	0.858231799101235	1
GO:0070001	aspartic-type peptidase activity	5/3563	37/18639	0.135135135135135	0.706927809088909	0.86162374399608	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	13/3563	86/18639	0.151162790697674	0.790772735283175	0.862048110309706	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/3563	17/18639	0.117647058823529	0.61544303379505	0.863916549480816	1
GO:0008484	sulfuric ester hydrolase activity	2/3563	17/18639	0.117647058823529	0.61544303379505	0.863916549480816	1
GO:0016018	cyclosporin A binding	2/3563	17/18639	0.117647058823529	0.61544303379505	0.863916549480816	1
GO:0045125	bioactive lipid receptor activity	2/3563	17/18639	0.117647058823529	0.61544303379505	0.863916549480816	1
GO:1990226	histone methyltransferase binding	2/3563	17/18639	0.117647058823529	0.61544303379505	0.863916549480816	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/3563	24/18639	0.125	0.653908223407241	0.864372025817201	1
GO:0170055	lipid transmembrane transporter activity	8/3563	56/18639	0.142857142857143	0.74732368389399	0.864411926329996	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	19/3563	122/18639	0.155737704918033	0.814705327523776	0.868835397773376	1
GO:0000510	H3-H4 histone complex chaperone activity	24/3563	151/18639	0.158940397350993	0.831459462875432	0.868893868751222	1
GO:0140584	chromatin extrusion motor activity	24/3563	151/18639	0.158940397350993	0.831459462875432	0.868893868751222	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	24/3563	151/18639	0.158940397350993	0.831459462875432	0.868893868751222	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	24/3563	151/18639	0.158940397350993	0.831459462875432	0.868893868751222	1
GO:0140457	protein demethylase activity	4/3563	31/18639	0.129032258064516	0.675002037065539	0.869831155943608	1
GO:0030547	signaling receptor inhibitor activity	6/3563	44/18639	0.136363636363636	0.713354425535172	0.871075676422495	1
GO:0043014	alpha-tubulin binding	6/3563	44/18639	0.136363636363636	0.713354425535172	0.871075676422495	1
GO:0051213	dioxygenase activity	14/3563	93/18639	0.150537634408602	0.787502376576462	0.872985098254009	1
GO:0015616	DNA translocase activity	24/3563	152/18639	0.157894736842105	0.825989334830199	0.87677853394318	1
GO:0140658	ATP-dependent chromatin remodeler activity	25/3563	158/18639	0.158227848101266	0.827731928363596	0.87844523291316	1
GO:0015081	sodium ion transmembrane transporter activity	26/3563	164/18639	0.158536585365854	0.829347015053086	0.880121116268269	1
GO:0031406	carboxylic acid binding	30/3563	187/18639	0.160427807486631	0.839240500629614	0.880137224599555	1
GO:0016830	carbon-carbon lyase activity	7/3563	51/18639	0.137254901960784	0.718016872760892	0.880151769629554	1
GO:0004935	adrenergic receptor activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0005337	nucleoside transmembrane transporter activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0019531	oxalate transmembrane transporter activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0032052	bile acid binding	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0032356	oxidized DNA binding	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0032395	MHC class II receptor activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0042166	acetylcholine binding	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0051880	G-quadruplex DNA binding	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0140940	histone H2A methyltransferase activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0141109	transporter activator activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:1990763	arrestin family protein binding	1/3563	10/18639	0.1	0.523126578725793	0.880219172580397	1
GO:0141108	transporter regulator activity	27/3563	170/18639	0.158823529411765	0.830848095623318	0.881801232385123	1
GO:0005537	D-mannose binding	3/3563	25/18639	0.12	0.627751894470951	0.882487762143688	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/3563	25/18639	0.12	0.627751894470951	0.882487762143688	1
GO:0061775	cohesin loader activity	24/3563	153/18639	0.156862745098039	0.820590711726734	0.884290502858268	1
GO:0000400	four-way junction DNA binding	2/3563	18/18639	0.111111111111111	0.58125175413977	0.884763272996165	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/3563	18/18639	0.111111111111111	0.58125175413977	0.884763272996165	1
GO:0015280	ligand-gated sodium channel activity	2/3563	18/18639	0.111111111111111	0.58125175413977	0.884763272996165	1
GO:0015373	monoatomic anion:sodium symporter activity	2/3563	18/18639	0.111111111111111	0.58125175413977	0.884763272996165	1
GO:0034185	apolipoprotein binding	2/3563	18/18639	0.111111111111111	0.58125175413977	0.884763272996165	1
GO:0022884	macromolecule transmembrane transporter activity	4/3563	32/18639	0.125	0.653908223407241	0.885622436061106	1
GO:0005254	chloride channel activity	12/3563	83/18639	0.144578313253012	0.756327583699941	0.892368639006308	1
GO:0099106	ion channel regulator activity	25/3563	160/18639	0.15625	0.817385279259051	0.892708610089913	1
GO:0008066	glutamate receptor activity	3/3563	26/18639	0.115384615384615	0.603607590837453	0.898412796051017	1
GO:0019865	immunoglobulin binding	3/3563	26/18639	0.115384615384615	0.603607590837453	0.898412796051017	1
GO:0050681	nuclear androgen receptor binding	3/3563	26/18639	0.115384615384615	0.603607590837453	0.898412796051017	1
GO:0052742	phosphatidylinositol kinase activity	3/3563	26/18639	0.115384615384615	0.603607590837453	0.898412796051017	1
GO:0070006	metalloaminopeptidase activity	3/3563	26/18639	0.115384615384615	0.603607590837453	0.898412796051017	1
GO:0001786	phosphatidylserine binding	8/3563	59/18639	0.135593220338983	0.709324174543448	0.899416750698096	1
GO:0019239	deaminase activity	4/3563	33/18639	0.121212121212121	0.634092822697931	0.899714407126241	1
GO:0015245	fatty acid transmembrane transporter activity	2/3563	19/18639	0.105263157894737	0.550659556553466	0.902615128461502	1
GO:0070003	threonine-type peptidase activity	2/3563	19/18639	0.105263157894737	0.550659556553466	0.902615128461502	1
GO:0008146	sulfotransferase activity	7/3563	53/18639	0.132075471698113	0.690921896430292	0.903108347859411	1
GO:0017046	peptide hormone binding	7/3563	53/18639	0.132075471698113	0.690921896430292	0.903108347859411	1
GO:0001851	complement component C3b binding	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0005536	D-glucose binding	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0008199	ferric iron binding	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0008432	JUN kinase binding	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0008526	phosphatidylinositol transfer activity	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0019215	intermediate filament binding	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0019864	IgG binding	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0050786	RAGE receptor binding	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3563	11/18639	0.0909090909090909	0.475569617023448	0.903128565897056	1
GO:0050997	quaternary ammonium group binding	5/3563	40/18639	0.125	0.653908223407241	0.903364533644387	1
GO:0016247	channel regulator activity	26/3563	168/18639	0.154761904761905	0.809600657551822	0.906583402778696	1
GO:0015108	chloride transmembrane transporter activity	18/3563	121/18639	0.148760330578512	0.778204827856551	0.907560254093026	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	13/3563	91/18639	0.142857142857143	0.74732368389399	0.908610451054937	1
GO:0015020	glucuronosyltransferase activity	4/3563	34/18639	0.117647058823529	0.61544303379505	0.91225047492581	1
GO:0008320	protein transmembrane transporter activity	3/3563	27/18639	0.111111111111111	0.58125175413977	0.912365203688561	1
GO:0140318	protein transporter activity	5/3563	41/18639	0.121951219512195	0.637959242348528	0.914602545830286	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/3563	20/18639	0.1	0.523126578725793	0.917854986253595	1
GO:0016408	C-acyltransferase activity	2/3563	20/18639	0.1	0.523126578725793	0.917854986253595	1
GO:0043024	ribosomal small subunit binding	2/3563	20/18639	0.1	0.523126578725793	0.917854986253595	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	6/3563	48/18639	0.125	0.653908223407241	0.918132513578176	1
GO:0003774	cytoskeletal motor activity	23/3563	153/18639	0.150326797385621	0.786399432071453	0.921620042415406	1
GO:0004126	cytidine deaminase activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0005078	MAP-kinase scaffold activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0005165	neurotrophin receptor binding	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0008179	adenylate cyclase binding	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0008504	monoamine transmembrane transporter activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0015166	polyol transmembrane transporter activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0070679	inositol 1,4,5 trisphosphate binding	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0097371	MDM2/MDM4 family protein binding	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3563	12/18639	0.0833333333333333	0.435938815604827	0.921657281792954	1
GO:0016887	ATP hydrolysis activity	69/3563	417/18639	0.165467625899281	0.8656051302657	0.923050135242466	1
GO:0034061	DNA polymerase activity	4/3563	35/18639	0.114285714285714	0.597858947115192	0.923369582671419	1
GO:0140566	histone reader activity	4/3563	35/18639	0.114285714285714	0.597858947115192	0.923369582671419	1
GO:0004520	DNA endonuclease activity	5/3563	42/18639	0.119047619047619	0.622769736578325	0.92467309662231	1
GO:0015631	tubulin binding	63/3563	385/18639	0.163636363636364	0.856025310642207	0.929099644373474	1
GO:0030170	pyridoxal phosphate binding	7/3563	56/18639	0.125	0.653908223407241	0.930457208303162	1
GO:0001846	opsonin binding	2/3563	21/18639	0.0952380952380952	0.49821578926266	0.930828817661428	1
GO:0005248	voltage-gated sodium channel activity	2/3563	21/18639	0.0952380952380952	0.49821578926266	0.930828817661428	1
GO:0008373	sialyltransferase activity	2/3563	21/18639	0.0952380952380952	0.49821578926266	0.930828817661428	1
GO:0010314	phosphatidylinositol-5-phosphate binding	2/3563	21/18639	0.0952380952380952	0.49821578926266	0.930828817661428	1
GO:0004866	endopeptidase inhibitor activity	24/3563	161/18639	0.149068322981366	0.779816017976337	0.932159264101707	1
GO:0004867	serine-type endopeptidase inhibitor activity	13/3563	95/18639	0.136842105263158	0.715857423519506	0.935718500157873	1
GO:0140375	immune receptor activity	23/3563	156/18639	0.147435897435897	0.771276366070079	0.936626616975864	1
GO:0004465	lipoprotein lipase activity	1/3563	13/18639	0.0769230769230769	0.402405060558302	0.936642792340638	1
GO:0005542	folic acid binding	1/3563	13/18639	0.0769230769230769	0.402405060558302	0.936642792340638	1
GO:0039706	co-receptor binding	1/3563	13/18639	0.0769230769230769	0.402405060558302	0.936642792340638	1
GO:0071837	HMG box domain binding	1/3563	13/18639	0.0769230769230769	0.402405060558302	0.936642792340638	1
GO:0008083	growth factor activity	24/3563	162/18639	0.148148148148148	0.775002338853026	0.936775670756837	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	19/3563	132/18639	0.143939393939394	0.752985226953793	0.936857660665067	1
GO:0016782	transferase activity, transferring sulphur-containing groups	9/3563	70/18639	0.128571428571429	0.672591315504591	0.937568703941609	1
GO:0070279	vitamin B6 binding	7/3563	57/18639	0.12280701754386	0.642436149312377	0.937934189593025	1
GO:0008970	phospholipase A1 activity	2/3563	22/18639	0.0909090909090909	0.475569617023448	0.941845808126738	1
GO:0140784	metal ion sensor activity	2/3563	22/18639	0.0909090909090909	0.475569617023448	0.941845808126738	1
GO:0022829	wide pore channel activity	4/3563	37/18639	0.108108108108108	0.565542247271127	0.94188103531143	1
GO:0016597	amino acid binding	6/3563	51/18639	0.117647058823529	0.61544303379505	0.942824241276733	1
GO:0008017	microtubule binding	43/3563	276/18639	0.155797101449275	0.815016046565547	0.946134565175212	1
GO:0016829	lyase activity	30/3563	200/18639	0.15	0.784689868088689	0.94631116061873	1
GO:0004065	arylsulfatase activity	1/3563	14/18639	0.0714285714285714	0.373661841946995	0.948762503008001	1
GO:0008494	translation activator activity	1/3563	14/18639	0.0714285714285714	0.373661841946995	0.948762503008001	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/3563	14/18639	0.0714285714285714	0.373661841946995	0.948762503008001	1
GO:0019763	immunoglobulin receptor activity	1/3563	14/18639	0.0714285714285714	0.373661841946995	0.948762503008001	1
GO:0032454	histone H3K9 demethylase activity	1/3563	14/18639	0.0714285714285714	0.373661841946995	0.948762503008001	1
GO:0042043	neurexin family protein binding	1/3563	14/18639	0.0714285714285714	0.373661841946995	0.948762503008001	1
GO:0004222	metalloendopeptidase activity	15/3563	110/18639	0.136363636363636	0.713354425535172	0.948806842208167	1
GO:0005539	glycosaminoglycan binding	37/3563	242/18639	0.152892561983471	0.799821628630344	0.949059330511713	1
GO:0000146	microfilament motor activity	4/3563	38/18639	0.105263157894737	0.550659556553466	0.949516586411292	1
GO:0003887	DNA-directed DNA polymerase activity	2/3563	23/18639	0.0869565217391304	0.454892677152863	0.95117977525306	1
GO:0005212	structural constituent of eye lens	2/3563	23/18639	0.0869565217391304	0.454892677152863	0.95117977525306	1
GO:0016493	C-C chemokine receptor activity	2/3563	23/18639	0.0869565217391304	0.454892677152863	0.95117977525306	1
GO:0016849	phosphorus-oxygen lyase activity	2/3563	23/18639	0.0869565217391304	0.454892677152863	0.95117977525306	1
GO:0008327	methyl-CpG binding	3/3563	31/18639	0.0967741935483871	0.506251527799154	0.952371644827432	1
GO:0020037	heme binding	20/3563	142/18639	0.140845070422535	0.736797998205342	0.953649921743872	1
GO:0000049	tRNA binding	10/3563	80/18639	0.125	0.653908223407241	0.956793095048642	1
GO:0004089	carbonate dehydratase activity	1/3563	15/18639	0.0666666666666667	0.348751052483862	0.958564339345316	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/3563	15/18639	0.0666666666666667	0.348751052483862	0.958564339345316	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/3563	15/18639	0.0666666666666667	0.348751052483862	0.958564339345316	1
GO:0008242	omega peptidase activity	1/3563	15/18639	0.0666666666666667	0.348751052483862	0.958564339345316	1
GO:0015250	water channel activity	1/3563	15/18639	0.0666666666666667	0.348751052483862	0.958564339345316	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/3563	15/18639	0.0666666666666667	0.348751052483862	0.958564339345316	1
GO:0008081	phosphoric diester hydrolase activity	11/3563	87/18639	0.126436781609195	0.661424409883187	0.959004819307655	1
GO:0004806	triacylglycerol lipase activity	2/3563	24/18639	0.0833333333333333	0.435938815604827	0.959071388838138	1
GO:0140612	DNA damage sensor activity	2/3563	24/18639	0.0833333333333333	0.435938815604827	0.959071388838138	1
GO:0004177	aminopeptidase activity	4/3563	40/18639	0.1	0.523126578725793	0.962093330678816	1
GO:0071855	neuropeptide receptor binding	4/3563	40/18639	0.1	0.523126578725793	0.962093330678816	1
GO:0030414	peptidase inhibitor activity	24/3563	169/18639	0.142011834319527	0.742901650261481	0.962242442094539	1
GO:0046943	carboxylic acid transmembrane transporter activity	27/3563	188/18639	0.143617021276596	0.751298809872149	0.964509539610106	1
GO:0015645	fatty acid ligase activity	2/3563	25/18639	0.08	0.418501262980634	0.965730834637655	1
GO:0120515	fatty acid-CoA ligase activity	2/3563	25/18639	0.08	0.418501262980634	0.965730834637655	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0008296	3'-5'-DNA exonuclease activity	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0022841	potassium ion leak channel activity	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0055102	lipase inhibitor activity	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3563	16/18639	0.0625	0.326954111703621	0.966491490274904	1
GO:0005342	organic acid transmembrane transporter activity	27/3563	189/18639	0.142857142857143	0.74732368389399	0.967034243472513	1
GO:0001530	lipopolysaccharide binding	4/3563	41/18639	0.0975609756097561	0.510367393878822	0.967227469581359	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/3563	41/18639	0.0975609756097561	0.510367393878822	0.967227469581359	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/3563	70/18639	0.114285714285714	0.597858947115192	0.970081089512048	1
GO:0051427	hormone receptor binding	3/3563	34/18639	0.0882352941176471	0.461582275346288	0.970360306276108	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/3563	26/18639	0.0769230769230769	0.402405060558302	0.971340671186542	1
GO:0004950	chemokine receptor activity	2/3563	26/18639	0.0769230769230769	0.402405060558302	0.971340671186542	1
GO:0030507	spectrin binding	2/3563	26/18639	0.0769230769230769	0.402405060558302	0.971340671186542	1
GO:0008307	structural constituent of muscle	4/3563	42/18639	0.0952380952380952	0.49821578926266	0.971706877261259	1
GO:0009881	photoreceptor activity	1/3563	17/18639	0.0588235294117647	0.307721516897525	0.972902424074534	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/3563	17/18639	0.0588235294117647	0.307721516897525	0.972902424074534	1
GO:0045236	CXCR chemokine receptor binding	1/3563	17/18639	0.0588235294117647	0.307721516897525	0.972902424074534	1
GO:0004536	DNA nuclease activity	7/3563	64/18639	0.109375	0.572169695481336	0.973115414034773	1
GO:0008094	ATP-dependent activity, acting on DNA	30/3563	210/18639	0.142857142857143	0.74732368389399	0.973257595965725	1
GO:0005104	fibroblast growth factor receptor binding	2/3563	27/18639	0.0740740740740741	0.387501169426513	0.97605870858638	1
GO:0016405	CoA-ligase activity	2/3563	27/18639	0.0740740740740741	0.387501169426513	0.97605870858638	1
GO:0005272	sodium channel activity	5/3563	51/18639	0.0980392156862745	0.512869194829209	0.977358661737498	1
GO:0030544	Hsp70 protein binding	5/3563	51/18639	0.0980392156862745	0.512869194829209	0.977358661737498	1
GO:0004970	glutamate-gated receptor activity	1/3563	18/18639	0.0555555555555556	0.290625877069885	0.978087080020321	1
GO:0005372	water transmembrane transporter activity	1/3563	18/18639	0.0555555555555556	0.290625877069885	0.978087080020321	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/3563	36/18639	0.0833333333333333	0.435938815604827	0.978543969816648	1
GO:0015459	potassium channel regulator activity	6/3563	59/18639	0.101694915254237	0.531993130907586	0.979443258737426	1
GO:0005242	inward rectifier potassium channel activity	2/3563	28/18639	0.0714285714285714	0.373661841946995	0.980020796495823	1
GO:0031491	nucleosome binding	8/3563	74/18639	0.108108108108108	0.565542247271127	0.981493270614999	1
GO:0022840	leak channel activity	1/3563	19/18639	0.0526315789473684	0.275329778276733	0.982279966218033	1
GO:0022842	narrow pore channel activity	1/3563	19/18639	0.0526315789473684	0.275329778276733	0.982279966218033	1
GO:0030506	ankyrin binding	1/3563	19/18639	0.0526315789473684	0.275329778276733	0.982279966218033	1
GO:0005125	cytokine activity	33/3563	234/18639	0.141025641025641	0.737742611023554	0.982528885500803	1
GO:0016874	ligase activity	22/3563	167/18639	0.131736526946108	0.689148786345356	0.983789762920749	1
GO:0004386	helicase activity	20/3563	155/18639	0.129032258064516	0.675002037065539	0.984697746060943	1
GO:0046873	metal ion transmembrane transporter activity	69/3563	450/18639	0.153333333333333	0.802127420712882	0.98512142890772	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/3563	20/18639	0.05	0.261563289362896	0.985670754637214	1
GO:0015464	acetylcholine receptor activity	1/3563	20/18639	0.05	0.261563289362896	0.985670754637214	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/3563	20/18639	0.05	0.261563289362896	0.985670754637214	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	24/3563	181/18639	0.132596685082873	0.693648502177847	0.985671365834199	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/3563	47/18639	0.0851063829787234	0.445214109553866	0.986695130872504	1
GO:0003724	RNA helicase activity	8/3563	77/18639	0.103896103896104	0.543508133741084	0.987244926994175	1
GO:0015125	bile acid transmembrane transporter activity	1/3563	21/18639	0.0476190476190476	0.24910789463133	0.988412851486003	1
GO:0051428	peptide hormone receptor binding	1/3563	21/18639	0.0476190476190476	0.24910789463133	0.988412851486003	1
GO:0061891	calcium ion sensor activity	1/3563	21/18639	0.0476190476190476	0.24910789463133	0.988412851486003	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/3563	31/18639	0.0645161290322581	0.33750101853277	0.988454184894357	1
GO:0016878	acid-thiol ligase activity	2/3563	31/18639	0.0645161290322581	0.33750101853277	0.988454184894357	1
GO:0047499	calcium-independent phospholipase A2 activity	2/3563	31/18639	0.0645161290322581	0.33750101853277	0.988454184894357	1
GO:0008201	heparin binding	22/3563	172/18639	0.127906976744186	0.669115391393456	0.989588938963826	1
GO:0008186	ATP-dependent activity, acting on RNA	8/3563	79/18639	0.10126582278481	0.529748434152702	0.99010049212409	1
GO:0016835	carbon-oxygen lyase activity	8/3563	79/18639	0.10126582278481	0.529748434152702	0.99010049212409	1
GO:0047498	calcium-dependent phospholipase A2 activity	2/3563	32/18639	0.0625	0.326954111703621	0.990399348194683	1
GO:0005506	iron ion binding	19/3563	154/18639	0.123376623376623	0.645415908817537	0.99077419599853	1
GO:0030296	protein tyrosine kinase activator activity	2/3563	33/18639	0.0606060606060606	0.317046411348965	0.992022985612676	1
GO:0031492	nucleosomal DNA binding	3/3563	42/18639	0.0714285714285714	0.373661841946995	0.992084117055224	1
GO:0042056	chemoattractant activity	3/3563	42/18639	0.0714285714285714	0.373661841946995	0.992084117055224	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/3563	23/18639	0.0434782608695652	0.227446338576432	0.992423536763395	1
GO:0043274	phospholipase binding	1/3563	23/18639	0.0434782608695652	0.227446338576432	0.992423536763395	1
GO:0099186	structural constituent of postsynapse	1/3563	23/18639	0.0434782608695652	0.227446338576432	0.992423536763395	1
GO:0004175	endopeptidase activity	59/3563	405/18639	0.145679012345679	0.762085633205476	0.993558809414811	1
GO:0015295	solute:proton symporter activity	1/3563	24/18639	0.0416666666666667	0.217969407802414	0.993873630151449	1
GO:0004623	phospholipase A2 activity	2/3563	35/18639	0.0571428571428571	0.298929473557596	0.994504855583767	1
GO:0016836	hydro-lyase activity	5/3563	61/18639	0.0819672131147541	0.428792277644092	0.994731700314867	1
GO:0015079	potassium ion transmembrane transporter activity	19/3563	160/18639	0.11875	0.621212812236879	0.994885169447738	1
GO:0005251	delayed rectifier potassium channel activity	1/3563	25/18639	0.04	0.209250631490317	0.995046246631191	1
GO:0015271	outward rectifier potassium channel activity	1/3563	25/18639	0.04	0.209250631490317	0.995046246631191	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/3563	25/18639	0.04	0.209250631490317	0.995046246631191	1
GO:0004497	monooxygenase activity	11/3563	106/18639	0.10377358490566	0.542867204338087	0.99509540526368	1
GO:0004435	phosphatidylinositol phospholipase C activity	1/3563	26/18639	0.0384615384615385	0.201202530279151	0.995994469648977	1
GO:0004529	DNA exonuclease activity	1/3563	26/18639	0.0384615384615385	0.201202530279151	0.995994469648977	1
GO:0015145	monosaccharide transmembrane transporter activity	1/3563	26/18639	0.0384615384615385	0.201202530279151	0.995994469648977	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/3563	46/18639	0.0652173913043478	0.341169507864648	0.996006455864215	1
GO:0008395	steroid hydroxylase activity	1/3563	27/18639	0.037037037037037	0.193750584713257	0.996761229689846	1
GO:0003730	mRNA 3'-UTR binding	34/3563	262/18639	0.129770992366412	0.678866552544922	0.996894679300985	1
GO:0051119	sugar transmembrane transporter activity	1/3563	28/18639	0.0357142857142857	0.186830920973497	0.997381245734069	1
GO:0015144	carbohydrate transmembrane transporter activity	2/3563	40/18639	0.05	0.261563289362896	0.997859499677202	1
GO:0004629	phospholipase C activity	1/3563	29/18639	0.0344827586206897	0.180388475422687	0.997882595551355	1
GO:0140097	catalytic activity, acting on DNA	45/3563	336/18639	0.133928571428571	0.700615953650615	0.997957852488886	1
GO:0003777	microtubule motor activity	5/3563	68/18639	0.0735294117647059	0.384651896121907	0.998208847249914	1
GO:0004812	aminoacyl-tRNA ligase activity	2/3563	41/18639	0.0487804878048781	0.255183696939411	0.998230315049003	1
GO:0008227	G protein-coupled amine receptor activity	2/3563	41/18639	0.0487804878048781	0.255183696939411	0.998230315049003	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/3563	41/18639	0.0487804878048781	0.255183696939411	0.998230315049003	1
GO:0098918	structural constituent of synapse	1/3563	30/18639	0.0333333333333333	0.174375526241931	0.998287985774381	1
GO:0099094	ligand-gated monoatomic cation channel activity	14/3563	136/18639	0.102941176470588	0.538512654570669	0.998291663204964	1
GO:0016298	lipase activity	13/3563	130/18639	0.1	0.523126578725793	0.998502795479979	1
GO:0005184	neuropeptide hormone activity	1/3563	31/18639	0.032258064516129	0.168750509266385	0.998615779137049	1
GO:0004620	phospholipase activity	10/3563	109/18639	0.0917431192660551	0.479932641032838	0.99865777047463	1
GO:0005262	calcium channel activity	13/3563	131/18639	0.099236641221374	0.519133246063764	0.998674852563409	1
GO:0005267	potassium channel activity	12/3563	124/18639	0.0967741935483871	0.506251527799154	0.998709485284466	1
GO:0005179	hormone activity	13/3563	132/18639	0.0984848484848485	0.515200418442069	0.998827929911232	1
GO:0160041	neuropeptide activity	1/3563	32/18639	0.03125	0.16347705585181	0.99888082529648	1
GO:0015085	calcium ion transmembrane transporter activity	15/3563	147/18639	0.102040816326531	0.53380263135285	0.998927708833249	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/3563	44/18639	0.0454545454545455	0.237784808511724	0.999002835928217	1
GO:0001653	peptide receptor activity	12/3563	128/18639	0.09375	0.490431167555431	0.999223131413149	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/3563	56/18639	0.0535714285714286	0.280246381460246	0.999314904837936	1
GO:0008528	G protein-coupled peptide receptor activity	11/3563	122/18639	0.0901639344262295	0.471671505408502	0.999354287788603	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/3563	36/18639	0.0277777777777778	0.145312938534942	0.999521796685741	1
GO:0005216	monoatomic ion channel activity	60/3563	448/18639	0.133928571428571	0.700615953650615	0.999529305780287	1
GO:0030280	structural constituent of skin epidermis	1/3563	37/18639	0.027027027027027	0.141385561817782	0.999613386128772	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/3563	69/18639	0.0579710144927536	0.303261784768576	0.999637760428407	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/3563	53/18639	0.0377358490566038	0.197406256122941	0.999825532227374	1
GO:0003823	antigen binding	16/3563	174/18639	0.0919540229885057	0.481035934460499	0.999905557179887	1
GO:0017171	serine hydrolase activity	19/3563	198/18639	0.095959595959596	0.501990151302528	0.99992710017732	1
GO:0015276	ligand-gated monoatomic ion channel activity	17/3563	186/18639	0.0913978494623656	0.478126442921424	0.999947441555221	1
GO:0008236	serine-type peptidase activity	18/3563	194/18639	0.0927835051546392	0.485375176137334	0.999951464480265	1
GO:0005261	monoatomic cation channel activity	39/3563	341/18639	0.114369501466276	0.598297260126273	0.999957709685846	1
GO:0022834	ligand-gated channel activity	17/3563	188/18639	0.0904255319148936	0.473039991400983	0.999959280166725	1
GO:0008188	neuropeptide receptor activity	1/3563	48/18639	0.0208333333333333	0.108984703901207	0.999962741480096	1
GO:0004252	serine-type endopeptidase activity	15/3563	176/18639	0.0852272727272727	0.445846515959483	0.999972680250107	1
GO:0022824	transmitter-gated monoatomic ion channel activity	2/3563	63/18639	0.0317460317460317	0.16607192975422	0.999975599511368	1
GO:0022835	transmitter-gated channel activity	2/3563	63/18639	0.0317460317460317	0.16607192975422	0.999975599511368	1
GO:0005249	voltage-gated potassium channel activity	5/3563	98/18639	0.0510204081632653	0.266901315676425	0.999987791060052	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/3563	73/18639	0.0273972602739726	0.143322350335834	0.999996667182313	1
GO:0030594	neurotransmitter receptor activity	4/3563	97/18639	0.0412371134020619	0.215722300505482	0.999997528814313	1
GO:0005244	voltage-gated monoatomic ion channel activity	12/3563	173/18639	0.069364161849711	0.362862366746215	0.999998592796937	1
GO:0022832	voltage-gated channel activity	12/3563	175/18639	0.0685714285714286	0.358715368269115	0.999998959020408	1
GO:0022836	gated channel activity	29/3563	318/18639	0.0911949685534591	0.477065118963773	0.999999777199927	1
GO:0022843	voltage-gated monoatomic cation channel activity	6/3563	143/18639	0.041958041958042	0.219493669395438	0.999999975440102	1
GO:0030527	structural constituent of chromatin	1/3563	98/18639	0.0102040816326531	0.053380263135285	0.99999999912027	1
GO:0004984	olfactory receptor activity	1/3563	419/18639	0.00238663484486874	0.0124851212106394	1	1
GO:0030371	translation repressor activity	9/3563	329/18639	0.027355623100304	0.143104535213743	1	1
GO:0045182	translation regulator activity	11/3563	356/18639	0.0308988764044944	0.161640234999543	1	1