ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	77/1218	489/18639	0.157464212678937	2.40966786545378	4.45254562526584e-13	2.58765005400521e-10
GO:0060589	nucleoside-triphosphatase regulator activity	77/1218	490/18639	0.157142857142857	2.40475017593244	4.95718401150424e-13	2.58765005400521e-10
GO:0141003	histone H2AX kinase activity	59/1218	354/18639	0.166666666666667	2.55049261083744	2.48521331001436e-11	8.36522452880472e-09
GO:0140996	histone H3 kinase activity	59/1218	357/18639	0.165266106442577	2.529059899822	3.53434318924377e-11	8.36522452880472e-09
GO:0003712	transcription coregulator activity	73/1218	495/18639	0.147474747474747	2.25679952231676	4.44434758543342e-11	8.36522452880472e-09
GO:0035173	histone kinase activity	59/1218	360/18639	0.163888888888889	2.50798440065681	5.00137214849159e-11	8.36522452880472e-09
GO:0106310	protein serine kinase activity	59/1218	361/18639	0.163434903047091	2.50103707544724	5.60886702122922e-11	8.36522452880472e-09
GO:0004674	protein serine/threonine kinase activity	65/1218	433/18639	0.150115473441109	2.29721043470347	2.480636738605e-10	3.23723094387953e-08
GO:0005096	GTPase activator activity	47/1218	271/18639	0.173431734317343	2.65401814116663	6.94716351451272e-10	8.05870967683475e-08
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	55/1218	349/18639	0.157593123209169	2.41164057758268	1.00701089644155e-09	9.43770744036056e-08
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	43/1218	243/18639	0.176954732510288	2.70793042632123	1.95312654428177e-09	9.43770744036056e-08
GO:0004676	3-phosphoinositide-dependent protein kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0004711	ribosomal protein S6 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0035175	histone H3S10 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0035979	histone H2AXS139 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0044022	histone H3S28 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0044023	histone H4S1 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0044024	histone H2AS1 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0044025	histone H2BS14 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0072354	histone H3T3 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0072371	histone H2AS121 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0072518	Rho-dependent protein serine/threonine kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0140823	histone H2BS36 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0140855	histone H3S57 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0140995	histone H2A kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0140997	histone H4 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0140998	histone H2B kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:1990244	histone H2AT120 kinase activity	43/1218	245/18639	0.175510204081633	2.68582487182065	2.53118590354498e-09	9.43770744036056e-08
GO:0004677	DNA-dependent protein kinase activity	43/1218	246/18639	0.17479674796748	2.67490688453683	2.87777171094454e-09	1.0014645554087e-07
GO:0140857	histone H3T45 kinase activity	43/1218	246/18639	0.17479674796748	2.67490688453683	2.87777171094454e-09	1.0014645554087e-07
GO:0035402	histone H3T11 kinase activity	43/1218	247/18639	0.174089068825911	2.66407730200834	3.26901405010821e-09	1.03419717221605e-07
GO:0035403	histone H3T6 kinase activity	43/1218	247/18639	0.174089068825911	2.66407730200834	3.26901405010821e-09	1.03419717221605e-07
GO:0042393	histone binding	43/1218	247/18639	0.174089068825911	2.66407730200834	3.26901405010821e-09	1.03419717221605e-07
GO:0004679	AMP-activated protein kinase activity	43/1218	248/18639	0.173387096774194	2.65333505482282	3.71029731756411e-09	1.13927952927557e-07
GO:0019787	ubiquitin-like protein transferase activity	66/1218	479/18639	0.137787056367432	2.10854921480506	6.52199509807752e-09	1.94541796639798e-07
GO:0016755	aminoacyltransferase activity	66/1218	496/18639	0.133064516129032	2.03628039091054	2.60645089073347e-08	7.55870758312705e-07
GO:0140297	DNA-binding transcription factor binding	65/1218	488/18639	0.133196721311475	2.03830352095615	3.20220167580426e-08	9.03540148524228e-07
GO:0005085	guanyl-nucleotide exchange factor activity	39/1218	230/18639	0.169565217391304	2.59484900406939	3.67513205171994e-08	1.00969417420937e-06
GO:0019902	phosphatase binding	34/1218	190/18639	0.178947368421053	2.7384236453202	7.12388360903225e-08	1.90700884303325e-06
GO:0004715	non-membrane spanning protein tyrosine kinase activity	15/1218	45/18639	0.333333333333333	5.10098522167488	8.31134944436274e-08	2.16926220497868e-06
GO:0003725	double-stranded RNA binding	19/1218	75/18639	0.253333333333333	3.87674876847291	2.29155064783418e-07	5.83507043009484e-06
GO:0003779	actin binding	58/1218	443/18639	0.130925507900677	2.0035472428249	3.17833354838524e-07	7.90042910598617e-06
GO:0003714	transcription corepressor activity	34/1218	204/18639	0.166666666666667	2.55049261083744	4.1259349482271e-07	1.00173862463932e-05
GO:0004842	ubiquitin-protein transferase activity	58/1218	449/18639	0.129175946547884	1.97677378300986	4.99352692160008e-07	1.18482775139784e-05
GO:0045296	cadherin binding	47/1218	334/18639	0.140718562874251	2.15340992891065	5.34070873514638e-07	1.23904442655396e-05
GO:0000287	magnesium ion binding	36/1218	230/18639	0.156521739130435	2.39524523452559	9.12785762766401e-07	2.07162681810461e-05
GO:0051219	phosphoprotein binding	20/1218	93/18639	0.21505376344086	3.29095820753218	1.8694967808937e-06	4.15266944521919e-05
GO:0061659	ubiquitin-like protein ligase activity	49/1218	372/18639	0.131720430107527	2.01571190211346	2.17885909753355e-06	4.73901853713547e-05
GO:0031267	small GTPase binding	40/1218	283/18639	0.141342756183746	2.16296193145224	3.29615998378305e-06	7.02283882259081e-05
GO:0051020	GTPase binding	43/1218	315/18639	0.136507936507936	2.08897490030495	3.59504359407395e-06	7.5064510244264e-05
GO:0044389	ubiquitin-like protein ligase binding	43/1218	322/18639	0.133540372670807	2.04356240247223	6.34352364907216e-06	0.000129855660581007
GO:0140033	acetylation-dependent protein binding	9/1218	24/18639	0.375	5.73860837438424	1.1248736191455e-05	0.000221852906096874
GO:0003713	transcription coactivator activity	36/1218	256/18639	0.140625	2.15197814039409	1.12626475317378e-05	0.000221852906096874
GO:0051015	actin filament binding	31/1218	209/18639	0.148325358851675	2.26981639050605	1.55401853789993e-05	0.000300139428816613
GO:0017124	SH3 domain binding	21/1218	115/18639	0.182608695652174	2.79445277361319	1.58119430889978e-05	0.000300139428816613
GO:0045309	protein phosphorylated amino acid binding	14/1218	59/18639	0.23728813559322	3.6312098188194	1.98487363543962e-05	0.000370037156321243
GO:0016922	nuclear receptor binding	23/1218	137/18639	0.167883211678832	2.56910934522311	2.63250727702152e-05	0.000482164490738678
GO:0001784	phosphotyrosine residue binding	12/1218	47/18639	0.25531914893617	3.90713761660203	3.53183265586872e-05	0.000614538882121157
GO:0061749	forked DNA-dependent helicase activity	12/1218	47/18639	0.25531914893617	3.90713761660203	3.53183265586872e-05	0.000614538882121157
GO:1990518	single-stranded 3'-5' DNA helicase activity	12/1218	47/18639	0.25531914893617	3.90713761660203	3.53183265586872e-05	0.000614538882121157
GO:0031625	ubiquitin protein ligase binding	39/1218	302/18639	0.129139072847682	1.97620950641047	3.62609660933132e-05	0.000620597518056049
GO:0009378	four-way junction helicase activity	12/1218	48/18639	0.25	3.82573891625616	4.43147763749723e-05	0.000722884789616736
GO:0036121	double-stranded DNA helicase activity	12/1218	48/18639	0.25	3.82573891625616	4.43147763749723e-05	0.000722884789616736
GO:0043138	3'-5' DNA helicase activity	12/1218	48/18639	0.25	3.82573891625616	4.43147763749723e-05	0.000722884789616736
GO:0061630	ubiquitin protein ligase activity	43/1218	353/18639	0.121813031161473	1.86409941528629	6.01534838553422e-05	0.000966157494538111
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	8/1218	23/18639	0.347826086956522	5.32276718783465	6.57135639347152e-05	0.00100889648158592
GO:0070577	lysine-acetylated histone binding	8/1218	23/18639	0.347826086956522	5.32276718783465	6.57135639347152e-05	0.00100889648158592
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	8/1218	23/18639	0.347826086956522	5.32276718783465	6.57135639347152e-05	0.00100889648158592
GO:0046975	histone H3K36 methyltransferase activity	6/1218	13/18639	0.461538461538462	7.06290261462675	8.85330233118358e-05	0.00133954313532691
GO:0035091	phosphatidylinositol binding	36/1218	284/18639	0.126760563380282	1.939811281482	0.000104504932429088	0.00155861642079954
GO:0019207	kinase regulator activity	36/1218	287/18639	0.125435540069686	1.91953450850483	0.000129394304883775	0.00190264301829101
GO:0019903	protein phosphatase binding	22/1218	144/18639	0.152777777777778	2.33795155993432	0.000165369148837282	0.00239785265814059
GO:0140938	histone H3 methyltransferase activity	11/1218	47/18639	0.234042553191489	3.58154281521853	0.00017389495869155	0.00248693612156135
GO:0004721	phosphoprotein phosphatase activity	25/1218	175/18639	0.142857142857143	2.18613652357495	0.000183529458146207	0.00258925343654919
GO:0016791	phosphatase activity	34/1218	273/18639	0.124542124542125	1.90586261029611	0.000225259171569662	0.0031356076682497
GO:0019209	kinase activator activity	22/1218	148/18639	0.148648648648649	2.27476367993609	0.000247040295524292	0.00339355353325475
GO:0008094	ATP-dependent activity, acting on DNA	28/1218	210/18639	0.133333333333333	2.04039408866995	0.000255647572664766	0.00346618267353268
GO:0003678	DNA helicase activity	14/1218	74/18639	0.189189189189189	2.89515377446412	0.000271645184832592	0.003635866320067
GO:0004713	protein tyrosine kinase activity	21/1218	140/18639	0.15	2.29544334975369	0.000298310837765205	0.00394223436236549
GO:0017116	single-stranded DNA helicase activity	12/1218	58/18639	0.206896551724138	3.16612875828096	0.000309444576043779	0.0039555836812446
GO:0046875	ephrin receptor binding	8/1218	28/18639	0.285714285714286	4.37227304714989	0.000310687607147565	0.0039555836812446
GO:0046966	nuclear thyroid hormone receptor binding	8/1218	28/18639	0.285714285714286	4.37227304714989	0.000310687607147565	0.0039555836812446
GO:0140030	modification-dependent protein binding	24/1218	173/18639	0.138728323699422	2.12295338705544	0.000381360800945877	0.00479687561671681
GO:0004386	helicase activity	22/1218	155/18639	0.141935483870968	2.17203241697124	0.000477231580836926	0.0059313067904018
GO:0016779	nucleotidyltransferase activity	20/1218	136/18639	0.147058823529412	2.25043465662127	0.000534150681970444	0.0065606271997311
GO:0140658	ATP-dependent chromatin remodeler activity	22/1218	158/18639	0.139240506329114	2.13079129513001	0.000622784080316682	0.00728560513192795
GO:0019887	protein kinase regulator activity	31/1218	255/18639	0.12156862745098	1.86035931614025	0.000631702696415335	0.00728560513192795
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	5/1218	12/18639	0.416666666666667	6.3762315270936	0.000635047956901766	0.00728560513192795
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	5/1218	12/18639	0.416666666666667	6.3762315270936	0.000635047956901766	0.00728560513192795
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	5/1218	12/18639	0.416666666666667	6.3762315270936	0.000635047956901766	0.00728560513192795
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	5/1218	12/18639	0.416666666666667	6.3762315270936	0.000635047956901766	0.00728560513192795
GO:0015631	tubulin binding	42/1218	385/18639	0.109090909090909	1.66941334527541	0.000775720800915741	0.00880274474082645
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	5/1218	13/18639	0.384615384615385	5.88575217885563	0.000976619790395472	0.0109633447437943
GO:0061775	cohesin loader activity	21/1218	153/18639	0.137254901960784	2.10040567951318	0.000988294260257794	0.0109763745500972
GO:0016763	pentosyltransferase activity	10/1218	49/18639	0.204081632653061	3.12305217653564	0.00108058693654068	0.011726657209881
GO:0052742	phosphatidylinositol kinase activity	7/1218	26/18639	0.269230769230769	4.12002652519894	0.00109355925979275	0.011726657209881
GO:0001727	lipid kinase activity	9/1218	41/18639	0.219512195121951	3.35918538988346	0.00110077816721105	0.011726657209881
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/1218	41/18639	0.219512195121951	3.35918538988346	0.00110077816721105	0.011726657209881
GO:0035401	histone H3Y41 kinase activity	17/1218	115/18639	0.147826086956522	2.26217605482973	0.00127673824904607	0.013329147320041
GO:0140801	histone H2AXY142 kinase activity	17/1218	115/18639	0.147826086956522	2.26217605482973	0.00127673824904607	0.013329147320041
GO:0019208	phosphatase regulator activity	17/1218	117/18639	0.145299145299145	2.22350637867879	0.00154816691478406	0.0159178372744571
GO:0042578	phosphoric ester hydrolase activity	39/1218	363/18639	0.107438016528926	1.64411920368033	0.00155519099807915	0.0159178372744571
GO:0048156	tau protein binding	9/1218	43/18639	0.209302325581395	3.20294420895864	0.00157523249067868	0.0159664341773645
GO:0019789	SUMO transferase activity	7/1218	28/18639	0.25	3.82573891625616	0.00175503776779419	0.0175338264653094
GO:0030295	protein kinase activator activity	19/1218	139/18639	0.136690647482014	2.09177091824078	0.00176662990803681	0.0175338264653094
GO:0051010	microtubule plus-end binding	6/1218	21/18639	0.285714285714286	4.37227304714989	0.00178025441122873	0.0175338264653094
GO:0000510	H3-H4 histone complex chaperone activity	20/1218	151/18639	0.132450331125828	2.02688154503638	0.00199379764697112	0.0189229522130713
GO:0140584	chromatin extrusion motor activity	20/1218	151/18639	0.132450331125828	2.02688154503638	0.00199379764697112	0.0189229522130713
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	20/1218	151/18639	0.132450331125828	2.02688154503638	0.00199379764697112	0.0189229522130713
GO:0140849	ATP-dependent H2AZ histone chaperone activity	20/1218	151/18639	0.132450331125828	2.02688154503638	0.00199379764697112	0.0189229522130713
GO:0016887	ATP hydrolysis activity	43/1218	417/18639	0.103117505995204	1.57800262253252	0.00205160804943973	0.0192962054379737
GO:0015616	DNA translocase activity	20/1218	152/18639	0.131578947368421	2.01354679802956	0.0021584317793832	0.0199416175015581
GO:0140674	ATP-dependent histone chaperone activity	20/1218	152/18639	0.131578947368421	2.01354679802956	0.0021584317793832	0.0199416175015581
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/1218	10/18639	0.4	6.12118226600985	0.00276988892678135	0.0243005381475608
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/1218	10/18639	0.4	6.12118226600985	0.00276988892678135	0.0243005381475608
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/1218	10/18639	0.4	6.12118226600985	0.00276988892678135	0.0243005381475608
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/1218	10/18639	0.4	6.12118226600985	0.00276988892678135	0.0243005381475608
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/1218	10/18639	0.4	6.12118226600985	0.00276988892678135	0.0243005381475608
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/1218	10/18639	0.4	6.12118226600985	0.00276988892678135	0.0243005381475608
GO:0034450	ubiquitin-ubiquitin ligase activity	5/1218	16/18639	0.3125	4.7821736453202	0.00281116775351826	0.0244571594556089
GO:0140789	histone phosphatase activity	18/1218	136/18639	0.132352941176471	2.02539119095914	0.00328730095558085	0.0283631586580695
GO:0035035	histone acetyltransferase binding	6/1218	24/18639	0.25	3.82573891625616	0.00373118065454148	0.0319291196995189
GO:0038191	neuropilin binding	5/1218	17/18639	0.294117647058824	4.50086931324254	0.00377046787365885	0.0320029956105678
GO:0042054	histone methyltransferase activity	11/1218	67/18639	0.164179104477612	2.51242555694434	0.00387804717167613	0.0326506552195958
GO:0003689	DNA clamp loader activity	20/1218	160/18639	0.125	1.91286945812808	0.00393648227652903	0.0328774999735705
GO:0051059	NF-kappaB binding	7/1218	32/18639	0.21875	3.34752155172414	0.0039693255844708	0.0328886976999009
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/1218	11/18639	0.363636363636364	5.56471115091805	0.00412898455354497	0.0336673682932792
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/1218	11/18639	0.363636363636364	5.56471115091805	0.00412898455354497	0.0336673682932792
GO:0140767	enzyme-substrate adaptor activity	18/1218	139/18639	0.129496402877698	1.98167771201758	0.0041600483810661	0.0336673682932792
GO:0005543	phospholipid binding	48/1218	497/18639	0.096579476861167	1.47795145255771	0.00433431298100409	0.0347436045454897
GO:0030145	manganese ion binding	11/1218	68/18639	0.161764705882353	2.4754781222834	0.00435959022553558	0.0347436045454897
GO:0019211	phosphatase activator activity	6/1218	25/18639	0.24	3.67270935960591	0.00464216111584884	0.0367152742798954
GO:0016279	protein-lysine N-methyltransferase activity	11/1218	69/18639	0.159420289855072	2.43960162775755	0.00488746453822058	0.038364759232348
GO:0046332	SMAD binding	12/1218	79/18639	0.151898734177215	2.32449959468729	0.00503041165793245	0.0391921624692648
GO:0140713	histone chaperone activity	20/1218	164/18639	0.121951219512195	1.86621410549081	0.00520451770351621	0.0402482702405254
GO:0016278	lysine N-methyltransferase activity	11/1218	70/18639	0.157142857142857	2.40475017593244	0.00546468334081758	0.0419494809398055
GO:0043548	phosphatidylinositol 3-kinase binding	6/1218	26/18639	0.230769230769231	3.53145130731338	0.00570674167266566	0.0434878708486347
GO:0000340	RNA 7-methylguanosine cap binding	4/1218	12/18639	0.333333333333333	5.10098522167488	0.00587595285186657	0.0441330559521489
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/1218	12/18639	0.333333333333333	5.10098522167488	0.00587595285186657	0.0441330559521489
GO:0005154	epidermal growth factor receptor binding	7/1218	35/18639	0.2	3.06059113300493	0.00668546520238	0.0495008912857072
GO:0010485	histone H4 acetyltransferase activity	7/1218	35/18639	0.2	3.06059113300493	0.00668546520238	0.0495008912857072
GO:0004722	protein serine/threonine phosphatase activity	14/1218	103/18639	0.135922330097087	2.08001339136257	0.00706170702249627	0.0519184657146909
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	12/1218	83/18639	0.144578313253012	2.21247551783489	0.0074947443417899	0.0543135338204753
GO:0043539	protein serine/threonine kinase activator activity	11/1218	73/18639	0.150684931506849	2.30592482623659	0.00752358406939217	0.0543135338204753
GO:0140097	catalytic activity, acting on DNA	34/1218	336/18639	0.101190476190476	1.54851337086559	0.0075435463639549	0.0543135338204753
GO:0000339	RNA cap binding	5/1218	20/18639	0.25	3.82573891625616	0.00802201535500803	0.0564280893816865
GO:0140939	histone H4 methyltransferase activity	5/1218	20/18639	0.25	3.82573891625616	0.00802201535500803	0.0564280893816865
GO:0004535	poly(A)-specific ribonuclease activity	4/1218	13/18639	0.307692307692308	4.7086017430845	0.00805343421252039	0.0564280893816865
GO:0140852	histone ubiquitin ligase activity	4/1218	13/18639	0.307692307692308	4.7086017430845	0.00805343421252039	0.0564280893816865
GO:0042826	histone deacetylase binding	16/1218	127/18639	0.125984251968504	1.92793142236531	0.00863220470167054	0.0600801447236269
GO:1901981	phosphatidylinositol phosphate binding	21/1218	185/18639	0.113513513513514	1.73709226467847	0.00957901419004424	0.066228415989445
GO:0010484	histone H3 acetyltransferase activity	6/1218	29/18639	0.206896551724138	3.16612875828096	0.00996182777503281	0.0676062242762102
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/1218	29/18639	0.206896551724138	3.16612875828096	0.00996182777503281	0.0676062242762102
GO:0072542	protein phosphatase activator activity	5/1218	21/18639	0.238095238095238	3.64356087262491	0.00997256564993905	0.0676062242762102
GO:0061733	protein-lysine-acetyltransferase activity	8/1218	47/18639	0.170212765957447	2.60475841106802	0.0104481399976898	0.0703732784360529
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	7/1218	38/18639	0.184210526315789	2.81896551724138	0.0105846087360467	0.0708354584643126
GO:0061665	SUMO ligase activity	4/1218	14/18639	0.285714285714286	4.37227304714989	0.01069965976214	0.0711493298832751
GO:0140597	protein carrier chaperone	21/1218	188/18639	0.111702127659574	1.70937270726339	0.0113901170141074	0.072931364155785
GO:0032182	ubiquitin-like protein binding	15/1218	120/18639	0.125	1.91286945812808	0.0115396051235488	0.072931364155785
GO:0004407	histone deacetylase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0032931	histone H3K56 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0033558	protein lysine deacetylase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0043992	histone H3K9 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0043993	histone H3K18 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0043994	histone H3K23 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0043999	histone H2AK5 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0044012	histone H2AK9 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0044014	histone H2BK5 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0044015	histone H2BK12 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0044016	histone H3K4 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0044017	histone H3K27 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0044018	histone H3K36 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0046972	histone H4K16 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0050321	tau-protein kinase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0140908	histone H3K122 acetyltransferase activity	5/1218	22/18639	0.227272727272727	3.47794446932378	0.0122250849877992	0.072931364155785
GO:0008408	3'-5' exonuclease activity	9/1218	58/18639	0.155172413793103	2.37459656871072	0.0123944500116295	0.0731535116099994
GO:0003697	single-stranded DNA binding	15/1218	121/18639	0.12396694214876	1.89706061963115	0.0124024631752585	0.0731535116099994
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/1218	15/18639	0.266666666666667	4.0807881773399	0.0138480578713383	0.079239147247418
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/1218	15/18639	0.266666666666667	4.0807881773399	0.0138480578713383	0.079239147247418
GO:0141050	histone H3K deacetylase activity	4/1218	15/18639	0.266666666666667	4.0807881773399	0.0138480578713383	0.079239147247418
GO:0141051	histone H4K deacetylase activity	4/1218	15/18639	0.266666666666667	4.0807881773399	0.0138480578713383	0.079239147247418
GO:0008017	microtubule binding	28/1218	276/18639	0.101449275362319	1.55247376311844	0.0138856841601681	0.079239147247418
GO:0004532	RNA exonuclease activity	7/1218	40/18639	0.175	2.67801724137931	0.0139655202045258	0.079239147247418
GO:0030331	nuclear estrogen receptor binding	7/1218	40/18639	0.175	2.67801724137931	0.0139655202045258	0.079239147247418
GO:0044013	histone H2B acetyltransferase activity	5/1218	23/18639	0.217391304347826	3.32672949239666	0.0147987859189511	0.0835131486453242
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/1218	60/18639	0.15	2.29544334975369	0.0153252834976745	0.0860193331804957
GO:0042169	SH2 domain binding	7/1218	41/18639	0.170731707317073	2.61269974768713	0.0159174372607955	0.0888652647073288
GO:0043178	alcohol binding	12/1218	92/18639	0.130434782608696	1.996037695438	0.0164545494807847	0.0913752641379746
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/1218	16/18639	0.25	3.82573891625616	0.0175270212439449	0.0958021475323483
GO:0004708	MAP kinase kinase activity	4/1218	16/18639	0.25	3.82573891625616	0.0175270212439449	0.0958021475323483
GO:0015923	mannosidase activity	4/1218	16/18639	0.25	3.82573891625616	0.0175270212439449	0.0958021475323483
GO:0043998	histone H2A acetyltransferase activity	5/1218	24/18639	0.208333333333333	3.1881157635468	0.0177113136201116	0.0963052678093569
GO:0004402	histone acetyltransferase activity	7/1218	42/18639	0.166666666666667	2.55049261083744	0.0180550822551141	0.0971624014141191
GO:0048487	beta-tubulin binding	7/1218	42/18639	0.166666666666667	2.55049261083744	0.0180550822551141	0.0971624014141191
GO:0004527	exonuclease activity	11/1218	84/18639	0.130952380952381	2.0039584799437	0.0205394308424978	0.109964952818296
GO:0008276	protein methyltransferase activity	12/1218	95/18639	0.126315789473684	1.93300492610837	0.0207597093960228	0.110577227599223
GO:0034212	protein N-acetyltransferase activity	8/1218	53/18639	0.150943396226415	2.30988010038108	0.0208953638151599	0.110614445570753
GO:0042974	nuclear retinoic acid receptor binding	5/1218	25/18639	0.2	3.06059113300493	0.0209786017461773	0.110614445570753
GO:0032183	SUMO binding	4/1218	17/18639	0.235294117647059	3.60069545059403	0.0217598068963407	0.113586191998898
GO:1990226	histone methyltransferase binding	4/1218	17/18639	0.235294117647059	3.60069545059403	0.0217598068963407	0.113586191998898
GO:0019888	protein phosphatase regulator activity	13/1218	107/18639	0.121495327102804	1.85923760416187	0.0221839194190885	0.115223939669295
GO:0043014	alpha-tubulin binding	7/1218	44/18639	0.159090909090909	2.43456112852665	0.0229197531168156	0.118456545811661
GO:0140463	chromatin-protein adaptor activity	8/1218	54/18639	0.148148148148148	2.26710454296661	0.0231714524615545	0.118495187583126
GO:0005522	profilin binding	3/1218	10/18639	0.3	4.59088669950739	0.0236082366065998	0.118495187583126
GO:0030957	Tat protein binding	3/1218	10/18639	0.3	4.59088669950739	0.0236082366065998	0.118495187583126
GO:0042975	peroxisome proliferator activated receptor binding	3/1218	10/18639	0.3	4.59088669950739	0.0236082366065998	0.118495187583126
GO:0051880	G-quadruplex DNA binding	3/1218	10/18639	0.3	4.59088669950739	0.0236082366065998	0.118495187583126
GO:0140999	histone H3K4 trimethyltransferase activity	3/1218	10/18639	0.3	4.59088669950739	0.0236082366065998	0.118495187583126
GO:0000175	3'-5'-RNA exonuclease activity	6/1218	35/18639	0.171428571428571	2.62336382828994	0.0244258072336136	0.120646987316548
GO:0061631	ubiquitin conjugating enzyme activity	6/1218	35/18639	0.171428571428571	2.62336382828994	0.0244258072336136	0.120646987316548
GO:0140566	histone reader activity	6/1218	35/18639	0.171428571428571	2.62336382828994	0.0244258072336136	0.120646987316548
GO:0050681	nuclear androgen receptor binding	5/1218	26/18639	0.192307692307692	2.94287608942781	0.0246147589065372	0.120646987316548
GO:0070412	R-SMAD binding	5/1218	26/18639	0.192307692307692	2.94287608942781	0.0246147589065372	0.120646987316548
GO:0008170	N-methyltransferase activity	12/1218	98/18639	0.122448979591837	1.87383130592138	0.025849135654098	0.126105129078871
GO:0016757	glycosyltransferase activity	26/1218	267/18639	0.0973782771535581	1.49017545801738	0.0273184313149489	0.132653219966542
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	14/1218	122/18639	0.114754098360656	1.75607687959299	0.0281357908079741	0.135989655571875
GO:0030276	clathrin binding	7/1218	46/18639	0.152173913043478	2.32871064467766	0.0286197552855112	0.137118309454216
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/1218	27/18639	0.185185185185185	2.83388067870826	0.0286319841580643	0.137118309454216
GO:0003727	single-stranded RNA binding	11/1218	89/18639	0.123595505617978	1.89137654286821	0.0301368718030088	0.143666183389686
GO:0032050	clathrin heavy chain binding	3/1218	11/18639	0.272727272727273	4.17353336318854	0.0309129561264954	0.1453744423246
GO:0032404	mismatch repair complex binding	3/1218	11/18639	0.272727272727273	4.17353336318854	0.0309129561264954	0.1453744423246
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/1218	11/18639	0.272727272727273	4.17353336318854	0.0309129561264954	0.1453744423246
GO:0008574	plus-end-directed microtubule motor activity	4/1218	19/18639	0.210526315789474	3.22167487684729	0.0319543355799312	0.148268117090881
GO:0042577	lipid phosphatase activity	4/1218	19/18639	0.210526315789474	3.22167487684729	0.0319543355799312	0.148268117090881
GO:0042800	histone H3K4 methyltransferase activity	4/1218	19/18639	0.210526315789474	3.22167487684729	0.0319543355799312	0.148268117090881
GO:0002020	protease binding	15/1218	136/18639	0.110294117647059	1.68782599246595	0.032295082483682	0.149186133243204
GO:0036408	histone H3K14 acetyltransferase activity	5/1218	28/18639	0.178571428571429	2.73267065446868	0.033040509649065	0.151290754708877
GO:0045499	chemorepellent activity	5/1218	28/18639	0.178571428571429	2.73267065446868	0.033040509649065	0.151290754708877
GO:0140693	molecular condensate scaffold activity	7/1218	48/18639	0.145833333333333	2.23168103448276	0.0352077459505968	0.160510422587
GO:0140104	molecular carrier activity	24/1218	249/18639	0.0963855421686747	1.47498367855659	0.036518504076747	0.164301808984957
GO:0070063	RNA polymerase binding	8/1218	59/18639	0.135593220338983	2.07497703932537	0.0371863949588142	0.164301808984957
GO:0003785	actin monomer binding	5/1218	29/18639	0.172413793103448	2.6384406319008	0.0378485683728217	0.164301808984957
GO:0033192	calmodulin-dependent protein phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:0140791	histone H2AXS140 phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:1990439	MAP kinase serine/threonine phosphatase activity	10/1218	81/18639	0.123456790123457	1.88925378580551	0.0378525822753334	0.164301808984957
GO:0097110	scaffold protein binding	9/1218	70/18639	0.128571428571429	1.96752287121745	0.0379279080128109	0.164301808984957
GO:0016273	arginine N-methyltransferase activity	3/1218	12/18639	0.25	3.82573891625616	0.0392586238847051	0.165935236176648
GO:0016274	protein-arginine N-methyltransferase activity	3/1218	12/18639	0.25	3.82573891625616	0.0392586238847051	0.165935236176648
GO:0034452	dynactin binding	3/1218	12/18639	0.25	3.82573891625616	0.0392586238847051	0.165935236176648
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/1218	12/18639	0.25	3.82573891625616	0.0392586238847051	0.165935236176648
GO:0070679	inositol 1,4,5 trisphosphate binding	3/1218	12/18639	0.25	3.82573891625616	0.0392586238847051	0.165935236176648
GO:0097677	STAT family protein binding	3/1218	12/18639	0.25	3.82573891625616	0.0392586238847051	0.165935236176648
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	10/1218	82/18639	0.121951219512195	1.86621410549081	0.0406913767327424	0.17060962774692
GO:0033549	MAP kinase phosphatase activity	10/1218	82/18639	0.121951219512195	1.86621410549081	0.0406913767327424	0.17060962774692
GO:0043995	histone H4K5 acetyltransferase activity	5/1218	30/18639	0.166666666666667	2.55049261083744	0.0430623848820075	0.178401308796888
GO:0043996	histone H4K8 acetyltransferase activity	5/1218	30/18639	0.166666666666667	2.55049261083744	0.0430623848820075	0.178401308796888
GO:0043997	histone H4K12 acetyltransferase activity	5/1218	30/18639	0.166666666666667	2.55049261083744	0.0430623848820075	0.178401308796888
GO:0000149	SNARE binding	12/1218	106/18639	0.113207547169811	1.73241007528581	0.0437781927577217	0.180517762380828
GO:0071949	FAD binding	6/1218	40/18639	0.15	2.29544334975369	0.0439190724566382	0.180517762380828
GO:0016836	hydro-lyase activity	8/1218	61/18639	0.131147540983607	2.00694500524913	0.0441091244008286	0.180587944605745
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/1218	21/18639	0.19047619047619	2.91484869809993	0.0445173803388026	0.180841031415214
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/1218	21/18639	0.19047619047619	2.91484869809993	0.0445173803388026	0.180841031415214
GO:0017018	myosin phosphatase activity	10/1218	84/18639	0.119047619047619	1.82178043631246	0.0467986814840108	0.188840634026359
GO:0030544	Hsp70 protein binding	7/1218	51/18639	0.137254901960784	2.10040567951318	0.0468483948398725	0.188840634026359
GO:0031072	heat shock protein binding	14/1218	131/18639	0.106870229007634	1.63543037641485	0.0472142718811117	0.189583460938002
GO:0005035	death receptor activity	3/1218	13/18639	0.230769230769231	3.53145130731338	0.0486201807863604	0.191935865275722
GO:0043560	insulin receptor substrate binding	3/1218	13/18639	0.230769230769231	3.53145130731338	0.0486201807863604	0.191935865275722
GO:0046974	histone H3K9 methyltransferase activity	3/1218	13/18639	0.230769230769231	3.53145130731338	0.0486201807863604	0.191935865275722
GO:0140333	glycerophospholipid flippase activity	3/1218	13/18639	0.230769230769231	3.53145130731338	0.0486201807863604	0.191935865275722
GO:0061650	ubiquitin-like protein conjugating enzyme activity	6/1218	41/18639	0.146341463414634	2.23945692658897	0.0487193527759256	0.191935865275722
GO:0031491	nucleosome binding	9/1218	74/18639	0.121621621621622	1.86117028358408	0.0513017486786598	0.201349720377898
GO:0005516	calmodulin binding	20/1218	207/18639	0.0966183574879227	1.47854644106518	0.0515822050208327	0.201372976101279
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/1218	22/18639	0.181818181818182	2.78235557545902	0.0516934459723589	0.201372976101279
GO:0019894	kinesin binding	6/1218	42/18639	0.142857142857143	2.18613652357495	0.0538300645293941	0.208916681667983
GO:0004725	protein tyrosine phosphatase activity	11/1218	98/18639	0.112244897959184	1.7176786970946	0.0547766829534992	0.211803174086864
GO:0019003	GDP binding	9/1218	75/18639	0.12	1.83635467980296	0.055072664515764	0.212161851492464
GO:0004705	JUN kinase activity	3/1218	14/18639	0.214285714285714	3.27920478536242	0.0589621410656932	0.219353411696251
GO:0005545	1-phosphatidylinositol binding	3/1218	14/18639	0.214285714285714	3.27920478536242	0.0589621410656932	0.219353411696251
GO:0008195	phosphatidate phosphatase activity	3/1218	14/18639	0.214285714285714	3.27920478536242	0.0589621410656932	0.219353411696251
GO:0019992	diacylglycerol binding	3/1218	14/18639	0.214285714285714	3.27920478536242	0.0589621410656932	0.219353411696251
GO:0034236	protein kinase A catalytic subunit binding	3/1218	14/18639	0.214285714285714	3.27920478536242	0.0589621410656932	0.219353411696251
GO:0098631	cell adhesion mediator activity	9/1218	76/18639	0.118421052631579	1.8121921182266	0.0590189305405773	0.219353411696251
GO:0004712	protein serine/threonine/tyrosine kinase activity	6/1218	43/18639	0.13953488372093	2.13529613930576	0.0592533286725938	0.219353411696251
GO:0005158	insulin receptor binding	4/1218	23/18639	0.173913043478261	2.66138359391733	0.0594607428257079	0.219353411696251
GO:0042171	lysophosphatidic acid acyltransferase activity	4/1218	23/18639	0.173913043478261	2.66138359391733	0.0594607428257079	0.219353411696251
GO:0043274	phospholipase binding	4/1218	23/18639	0.173913043478261	2.66138359391733	0.0594607428257079	0.219353411696251
GO:0071617	lysophospholipid acyltransferase activity	4/1218	23/18639	0.173913043478261	2.66138359391733	0.0594607428257079	0.219353411696251
GO:0140103	catalytic activity, acting on a glycoprotein	4/1218	23/18639	0.173913043478261	2.66138359391733	0.0594607428257079	0.219353411696251
GO:0015485	cholesterol binding	7/1218	54/18639	0.12962962962963	1.98371647509579	0.0606917042752419	0.222517027747338
GO:0044325	transmembrane transporter binding	14/1218	136/18639	0.102941176470588	1.57530425963489	0.0610253430499375	0.222517027747338
GO:0030296	protein tyrosine kinase activator activity	5/1218	33/18639	0.151515151515152	2.31862964621585	0.0611708687389713	0.222517027747338
GO:0071889	14-3-3 protein binding	5/1218	33/18639	0.151515151515152	2.31862964621585	0.0611708687389713	0.222517027747338
GO:0043130	ubiquitin binding	11/1218	100/18639	0.11	1.68332512315271	0.0616728079147228	0.22327493326138
GO:0005178	integrin binding	16/1218	161/18639	0.0993788819875776	1.52079062509562	0.061806949916225	0.22327493326138
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	10/1218	89/18639	0.112359550561798	1.71943322078928	0.0646755059525119	0.231569208943824
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	10/1218	89/18639	0.112359550561798	1.71943322078928	0.0646755059525119	0.231569208943824
GO:0001046	core promoter sequence-specific DNA binding	6/1218	44/18639	0.136363636363636	2.08676668159427	0.0649902090235061	0.231569208943824
GO:0001223	transcription coactivator binding	6/1218	44/18639	0.136363636363636	2.08676668159427	0.0649902090235061	0.231569208943824
GO:0030215	semaphorin receptor binding	4/1218	24/18639	0.166666666666667	2.55049261083744	0.0678106286668273	0.24075903153506
GO:0008376	acetylgalactosaminyltransferase activity	5/1218	34/18639	0.147058823529412	2.25043465662127	0.0680305692555966	0.24075903153506
GO:0140793	histone H2AXY142 phosphatase activity	10/1218	90/18639	0.111111111111111	1.70032840722496	0.0687116851534599	0.242347970608825
GO:0004559	alpha-mannosidase activity	3/1218	15/18639	0.2	3.06059113300493	0.070240661864282	0.246906568977476
GO:0070851	growth factor receptor binding	14/1218	139/18639	0.100719424460432	1.54130488712478	0.0705002881451314	0.246987586656098
GO:0140303	intramembrane lipid transporter activity	6/1218	45/18639	0.133333333333333	2.04039408866995	0.0710407249605942	0.248048551367426
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	21/1218	229/18639	0.091703056768559	1.40332781207649	0.0732643538787502	0.254959951498051
GO:0032934	sterol binding	8/1218	68/18639	0.117647058823529	1.80034772529702	0.074744203024107	0.259245674276305
GO:0031490	chromatin DNA binding	13/1218	128/18639	0.1015625	1.55420643472906	0.0752694815313221	0.260203108340067
GO:0019706	protein-cysteine S-palmitoyltransferase activity	4/1218	25/18639	0.16	2.44847290640394	0.076731014746951	0.263510458538871
GO:0019707	protein-cysteine S-acyltransferase activity	4/1218	25/18639	0.16	2.44847290640394	0.076731014746951	0.263510458538871
GO:0035591	signaling adaptor activity	13/1218	129/18639	0.10077519379845	1.54215832283194	0.0789580410862463	0.270269491455872
GO:0008080	N-acetyltransferase activity	8/1218	69/18639	0.115942028985507	1.77425572927822	0.0799567571439589	0.272793642020566
GO:0004707	MAP kinase activity	3/1218	16/18639	0.1875	2.86930418719212	0.0824053481612828	0.277519946710901
GO:0097027	ubiquitin-protein transferase activator activity	3/1218	16/18639	0.1875	2.86930418719212	0.0824053481612828	0.277519946710901
GO:0140327	flippase activity	3/1218	16/18639	0.1875	2.86930418719212	0.0824053481612828	0.277519946710901
GO:0140328	floppase activity	3/1218	16/18639	0.1875	2.86930418719212	0.0824053481612828	0.277519946710901
GO:0000993	RNA polymerase II complex binding	5/1218	36/18639	0.138888888888889	2.1254105090312	0.0829682394247233	0.277624493459651
GO:0016409	palmitoyltransferase activity	5/1218	36/18639	0.138888888888889	2.1254105090312	0.0829682394247233	0.277624493459651
GO:0019213	deacetylase activity	5/1218	37/18639	0.135135135135135	2.06796698176008	0.0910345764458129	0.302756847411027
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	6/1218	48/18639	0.125	1.91286945812808	0.0910590518075312	0.302756847411027
GO:0004659	prenyltransferase activity	3/1218	17/18639	0.176470588235294	2.70052158794552	0.0954008212894848	0.312220869674678
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/1218	17/18639	0.176470588235294	2.70052158794552	0.0954008212894848	0.312220869674678
GO:0015278	intracellularly gated calcium channel activity	3/1218	17/18639	0.176470588235294	2.70052158794552	0.0954008212894848	0.312220869674678
GO:0046965	nuclear retinoid X receptor binding	3/1218	17/18639	0.176470588235294	2.70052158794552	0.0954008212894848	0.312220869674678
GO:0070403	NAD+ binding	3/1218	17/18639	0.176470588235294	2.70052158794552	0.0954008212894848	0.312220869674678
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	4/1218	27/18639	0.148148148148148	2.26710454296661	0.0962196912738024	0.31391674278078
GO:0005518	collagen binding	8/1218	72/18639	0.111111111111111	1.70032840722496	0.0968547077817112	0.31500409633678
GO:0004540	RNA nuclease activity	12/1218	121/18639	0.0991735537190083	1.51764849570492	0.0973218213479931	0.315540315177965
GO:0060590	ATPase regulator activity	6/1218	49/18639	0.122448979591837	1.87383130592138	0.0983441961158248	0.317867928002852
GO:0141052	histone H3 demethylase activity	4/1218	28/18639	0.142857142857143	2.18613652357495	0.106749554877925	0.343970787939981
GO:0050660	flavin adenine dinucleotide binding	9/1218	86/18639	0.104651162790698	1.60147210447932	0.108335784770208	0.34800787476953
GO:0035064	methylated histone binding	8/1218	74/18639	0.108108108108108	1.65437358540807	0.109158816873567	0.348536611378696
GO:0000400	four-way junction DNA binding	3/1218	18/18639	0.166666666666667	2.55049261083744	0.109168076552523	0.348536611378696
GO:0043021	ribonucleoprotein complex binding	16/1218	177/18639	0.0903954802259887	1.38331802621692	0.117373132202026	0.373590091521082
GO:0016417	S-acyltransferase activity	4/1218	29/18639	0.137931034482759	2.11075250552064	0.117773712718742	0.373725702365855
GO:0140034	methylation-dependent protein binding	8/1218	76/18639	0.105263157894737	1.61083743842365	0.122275445431079	0.386835045545597
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/1218	19/18639	0.157894736842105	2.41625615763547	0.123645652984883	0.388813438904272
GO:1990380	K48-linked deubiquitinase activity	3/1218	19/18639	0.157894736842105	2.41625615763547	0.123645652984883	0.388813438904272
GO:0016877	ligase activity, forming carbon-sulfur bonds	5/1218	41/18639	0.121951219512195	1.86621410549081	0.127077981952355	0.398406646120895
GO:0001968	fibronectin binding	4/1218	30/18639	0.133333333333333	2.04039408866995	0.129267763155162	0.400461557074152
GO:0032452	histone demethylase activity	4/1218	30/18639	0.133333333333333	2.04039408866995	0.129267763155162	0.400461557074152
GO:0051721	protein phosphatase 2A binding	4/1218	30/18639	0.133333333333333	2.04039408866995	0.129267763155162	0.400461557074152
GO:0070566	adenylyltransferase activity	4/1218	30/18639	0.133333333333333	2.04039408866995	0.129267763155162	0.400461557074152
GO:0160215	deacylase activity	7/1218	65/18639	0.107692307692308	1.64801061007958	0.130643022689764	0.403524602627554
GO:0001221	transcription coregulator binding	11/1218	115/18639	0.0956521739130435	1.46376097665453	0.131047196127926	0.403578975686003
GO:0019210	kinase inhibitor activity	9/1218	90/18639	0.1	1.53029556650246	0.133036088722653	0.404224328050633
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0005031	tumor necrosis factor receptor activity	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0015279	store-operated calcium channel activity	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0043422	protein kinase B binding	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0140940	histone H2A methyltransferase activity	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:1905394	retromer complex binding	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:1990259	histone H2AQ104 methyltransferase activity	2/1218	10/18639	0.2	3.06059113300493	0.135515818790921	0.404224328050633
GO:0043175	RNA polymerase core enzyme binding	5/1218	42/18639	0.119047619047619	1.82178043631246	0.136976349171673	0.407416833433695
GO:0016004	phospholipase activator activity	3/1218	20/18639	0.15	2.29544334975369	0.138770636046423	0.409155310655439
GO:0030742	GTP-dependent protein binding	3/1218	20/18639	0.15	2.29544334975369	0.138770636046423	0.409155310655439
GO:0140664	ATP-dependent DNA damage sensor activity	3/1218	20/18639	0.15	2.29544334975369	0.138770636046423	0.409155310655439
GO:0003925	G protein activity	6/1218	54/18639	0.111111111111111	1.70032840722496	0.139128482071533	0.409155310655439
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	9/1218	91/18639	0.0989010989010989	1.51347913170573	0.139635922794971	0.409494110668398
GO:0016411	acylglycerol O-acyltransferase activity	4/1218	31/18639	0.129032258064516	1.97457492451931	0.141205774472359	0.411784437288108
GO:0140457	protein demethylase activity	4/1218	31/18639	0.129032258064516	1.97457492451931	0.141205774472359	0.411784437288108
GO:1990782	protein tyrosine kinase binding	11/1218	117/18639	0.094017094017094	1.43873942149804	0.142630841780584	0.414781612308997
GO:0016835	carbon-oxygen lyase activity	8/1218	79/18639	0.10126582278481	1.54966639645819	0.143421668384054	0.415922838313757
GO:0008374	O-acyltransferase activity	6/1218	55/18639	0.109090909090909	1.66941334527541	0.148106638521962	0.427136272422455
GO:0098632	cell-cell adhesion mediator activity	6/1218	55/18639	0.109090909090909	1.66941334527541	0.148106638521962	0.427136272422455
GO:0051213	dioxygenase activity	9/1218	93/18639	0.0967741935483871	1.48093119338948	0.153325825120898	0.429394764134374
GO:0120015	sterol transfer activity	4/1218	32/18639	0.125	1.91286945812808	0.153560565872353	0.429394764134374
GO:1990841	promoter-specific chromatin binding	7/1218	68/18639	0.102941176470588	1.57530425963489	0.154680076318714	0.429394764134374
GO:0016248	channel inhibitor activity	5/1218	44/18639	0.113636363636364	1.73897223466189	0.157743171801869	0.429394764134374
GO:0030971	receptor tyrosine kinase binding	8/1218	81/18639	0.0987654320987654	1.51140302864441	0.158455533869432	0.429394764134374
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0001851	complement component C3b binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0002162	dystroglycan binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0003953	NAD+ nucleosidase activity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0005225	volume-sensitive anion channel activity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0005536	D-glucose binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0019107	myristoyltransferase activity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0032794	GTPase activating protein binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0034056	estrogen response element binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0035252	UDP-xylosyltransferase activity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0042285	xylosyltransferase activity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0050998	nitric-oxide synthase binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0070990	snRNP binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0097493	structural molecule activity conferring elasticity	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0140031	phosphorylation-dependent protein binding	2/1218	11/18639	0.181818181818182	2.78235557545902	0.158760899383016	0.429394764134374
GO:0016410	N-acyltransferase activity	9/1218	94/18639	0.0957446808510638	1.46517660622576	0.16040927557984	0.432731999238638
GO:0002039	p53 binding	7/1218	69/18639	0.101449275362319	1.55247376311844	0.163116580096508	0.438901313455554
GO:0005496	steroid binding	10/1218	108/18639	0.0925925925925926	1.41694033935413	0.167896544259226	0.450124144946131
GO:0051539	4 iron, 4 sulfur cluster binding	5/1218	45/18639	0.111111111111111	1.70032840722496	0.168580977657028	0.450124144946131
GO:0141110	transporter inhibitor activity	5/1218	45/18639	0.111111111111111	1.70032840722496	0.168580977657028	0.450124144946131
GO:0008970	phospholipase A1 activity	3/1218	22/18639	0.136363636363636	2.08676668159427	0.170708890843798	0.452335233606409
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/1218	22/18639	0.136363636363636	2.08676668159427	0.170708890843798	0.452335233606409
GO:0070034	telomerase RNA binding	3/1218	22/18639	0.136363636363636	2.08676668159427	0.170708890843798	0.452335233606409
GO:0030165	PDZ domain binding	8/1218	83/18639	0.0963855421686747	1.47498367855659	0.174195886492831	0.460406343034217
GO:0016407	acetyltransferase activity	9/1218	96/18639	0.09375	1.43465209359606	0.175034806311115	0.461455398456577
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/1218	34/18639	0.117647058823529	1.80034772529702	0.179407092789231	0.465118180682721
GO:0030291	protein serine/threonine kinase inhibitor activity	5/1218	46/18639	0.108695652173913	1.66336474619833	0.179700137077171	0.465118180682721
GO:0004860	protein kinase inhibitor activity	8/1218	84/18639	0.0952380952380952	1.45742434904996	0.182318068786902	0.465118180682721
GO:0004300	enoyl-CoA hydratase activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0005078	MAP-kinase scaffold activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0005095	GTPase inhibitor activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0008179	adenylate cyclase binding	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0008603	cAMP-dependent protein kinase regulator activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0035259	nuclear glucocorticoid receptor binding	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0036009	protein-glutamine N-methyltransferase activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0070410	co-SMAD binding	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/1218	12/18639	0.166666666666667	2.55049261083744	0.182661354482678	0.465118180682721
GO:0003887	DNA-directed DNA polymerase activity	3/1218	23/18639	0.130434782608696	1.996037695438	0.187396113046512	0.476013484234934
GO:0043015	gamma-tubulin binding	4/1218	35/18639	0.114285714285714	1.74890921885996	0.192840520298475	0.488654133960213
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	6/1218	60/18639	0.1	1.53029556650246	0.196600405834208	0.496975360026424
GO:0003774	cytoskeletal motor activity	13/1218	153/18639	0.0849673202614379	1.30025113493673	0.200917689259332	0.506661999001793
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	14/1218	167/18639	0.0838323353293413	1.28288251084039	0.20327720681331	0.509491319412307
GO:0005315	phosphate transmembrane transporter activity	3/1218	24/18639	0.125	1.91286945812808	0.204479753672181	0.509491319412307
GO:0060229	lipase activator activity	3/1218	24/18639	0.125	1.91286945812808	0.204479753672181	0.509491319412307
GO:0070300	phosphatidic acid binding	3/1218	24/18639	0.125	1.91286945812808	0.204479753672181	0.509491319412307
GO:0140612	DNA damage sensor activity	3/1218	24/18639	0.125	1.91286945812808	0.204479753672181	0.509491319412307
GO:0019905	syntaxin binding	6/1218	61/18639	0.0983606557377049	1.50520875393685	0.206944856576887	0.510829524581621
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/1218	13/18639	0.153846153846154	2.35430087154225	0.207032476972917	0.510829524581621
GO:0031994	insulin-like growth factor I binding	2/1218	13/18639	0.153846153846154	2.35430087154225	0.207032476972917	0.510829524581621
GO:0071837	HMG box domain binding	2/1218	13/18639	0.153846153846154	2.35430087154225	0.207032476972917	0.510829524581621
GO:0004518	nuclease activity	17/1218	209/18639	0.0813397129186603	1.24473802060009	0.207463331822421	0.510829524581621
GO:0001222	transcription corepressor binding	5/1218	49/18639	0.102040816326531	1.56152608826782	0.214574816135439	0.525859408557273
GO:0035254	glutamate receptor binding	5/1218	49/18639	0.102040816326531	1.56152608826782	0.214574816135439	0.525859408557273
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	11/1218	128/18639	0.0859375	1.31509775246305	0.215138352715703	0.526005714836519
GO:0004197	cysteine-type endopeptidase activity	8/1218	88/18639	0.0909090909090909	1.39117778772951	0.216352587527115	0.527738554622215
GO:0003707	nuclear steroid receptor activity	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0004709	MAP kinase kinase kinase activity	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0008139	nuclear localization sequence binding	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0015662	P-type ion transporter activity	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0017025	TBP-class protein binding	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0120020	cholesterol transfer activity	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0140358	P-type transmembrane transporter activity	3/1218	25/18639	0.12	1.83635467980296	0.221900036252894	0.53133861891748
GO:0016798	hydrolase activity, acting on glycosyl bonds	11/1218	130/18639	0.0846153846153846	1.29486547934824	0.229744806891917	0.544833658575637
GO:0005161	platelet-derived growth factor receptor binding	2/1218	14/18639	0.142857142857143	2.18613652357495	0.231710866290788	0.544833658575637
GO:0030983	mismatched DNA binding	2/1218	14/18639	0.142857142857143	2.18613652357495	0.231710866290788	0.544833658575637
GO:0032036	myosin heavy chain binding	2/1218	14/18639	0.142857142857143	2.18613652357495	0.231710866290788	0.544833658575637
GO:0032454	histone H3K9 demethylase activity	2/1218	14/18639	0.142857142857143	2.18613652357495	0.231710866290788	0.544833658575637
GO:0042043	neurexin family protein binding	2/1218	14/18639	0.142857142857143	2.18613652357495	0.231710866290788	0.544833658575637
GO:0044548	S100 protein binding	2/1218	14/18639	0.142857142857143	2.18613652357495	0.231710866290788	0.544833658575637
GO:0046030	inositol trisphosphate phosphatase activity	2/1218	14/18639	0.142857142857143	2.18613652357495	0.231710866290788	0.544833658575637
GO:0000146	microfilament motor activity	4/1218	38/18639	0.105263157894737	1.61083743842365	0.234825342103441	0.550916083496613
GO:0004529	DNA exonuclease activity	3/1218	26/18639	0.115384615384615	1.76572565365669	0.239599167378007	0.557108086286502
GO:0008157	protein phosphatase 1 binding	3/1218	26/18639	0.115384615384615	1.76572565365669	0.239599167378007	0.557108086286502
GO:0070006	metalloaminopeptidase activity	3/1218	26/18639	0.115384615384615	1.76572565365669	0.239599167378007	0.557108086286502
GO:0097602	cullin family protein binding	3/1218	26/18639	0.115384615384615	1.76572565365669	0.239599167378007	0.557108086286502
GO:0000217	DNA secondary structure binding	4/1218	39/18639	0.102564102564103	1.5695339143615	0.249282903580813	0.578336336307486
GO:0120013	lipid transfer activity	6/1218	65/18639	0.0923076923076923	1.41258052292535	0.250086452205722	0.578914093354265
GO:0005080	protein kinase C binding	5/1218	52/18639	0.0961538461538462	1.47143804471391	0.251352663664901	0.580557922270258
GO:0000774	adenyl-nucleotide exchange factor activity	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0015929	hexosaminidase activity	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0017081	chloride channel regulator activity	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0033130	acetylcholine receptor binding	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0042809	nuclear vitamin D receptor binding	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0050700	CARD domain binding	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0051371	muscle alpha-actinin binding	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0120283	protein serine/threonine kinase binding	2/1218	15/18639	0.133333333333333	2.04039408866995	0.256552436202558	0.581931931545969
GO:0001671	ATPase activator activity	3/1218	27/18639	0.111111111111111	1.70032840722496	0.257521601891032	0.581931931545969
GO:0008266	poly(U) RNA binding	3/1218	27/18639	0.111111111111111	1.70032840722496	0.257521601891032	0.581931931545969
GO:0008235	metalloexopeptidase activity	6/1218	66/18639	0.0909090909090909	1.39117778772951	0.261251396877069	0.588812688773804
GO:0004177	aminopeptidase activity	4/1218	40/18639	0.1	1.53029556650246	0.263922998249238	0.588812688773804
GO:0032451	demethylase activity	4/1218	40/18639	0.1	1.53029556650246	0.263922998249238	0.588812688773804
GO:0061791	GTPase motor activity	4/1218	40/18639	0.1	1.53029556650246	0.263922998249238	0.588812688773804
GO:1990606	membrane scission GTPase motor activity	4/1218	40/18639	0.1	1.53029556650246	0.263922998249238	0.588812688773804
GO:0051018	protein kinase A binding	5/1218	53/18639	0.0943396226415094	1.44367506273817	0.263950515657223	0.588812688773804
GO:0048306	calcium-dependent protein binding	7/1218	80/18639	0.0875	1.33900862068966	0.267438288940622	0.595321052567184
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	6/1218	67/18639	0.0895522388059701	1.37041394015146	0.272543201473545	0.605393834762512
GO:0005319	lipid transporter activity	14/1218	178/18639	0.0786516853932584	1.2036032545525	0.274719651705087	0.606852323541339
GO:0051019	mitogen-activated protein kinase binding	3/1218	28/18639	0.107142857142857	1.63960239268121	0.275614247532605	0.606852323541339
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/1218	28/18639	0.107142857142857	1.63960239268121	0.275614247532605	0.606852323541339
GO:0097718	disordered domain specific binding	3/1218	28/18639	0.107142857142857	1.63960239268121	0.275614247532605	0.606852323541339
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	5/1218	54/18639	0.0925925925925926	1.41694033935413	0.276687457859844	0.606852323541339
GO:0051287	NAD binding	5/1218	54/18639	0.0925925925925926	1.41694033935413	0.276687457859844	0.606852323541339
GO:0017080	sodium channel regulator activity	4/1218	41/18639	0.0975609756097561	1.49297128439265	0.278717054065118	0.607052763779038
GO:0005159	insulin-like growth factor receptor binding	2/1218	16/18639	0.125	1.91286945812808	0.281430591637025	0.607052763779038
GO:0008296	3'-5'-DNA exonuclease activity	2/1218	16/18639	0.125	1.91286945812808	0.281430591637025	0.607052763779038
GO:0030275	LRR domain binding	2/1218	16/18639	0.125	1.91286945812808	0.281430591637025	0.607052763779038
GO:0043023	ribosomal large subunit binding	2/1218	16/18639	0.125	1.91286945812808	0.281430591637025	0.607052763779038
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/1218	16/18639	0.125	1.91286945812808	0.281430591637025	0.607052763779038
GO:0070411	I-SMAD binding	2/1218	16/18639	0.125	1.91286945812808	0.281430591637025	0.607052763779038
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/1218	16/18639	0.125	1.91286945812808	0.281430591637025	0.607052763779038
GO:0031492	nucleosomal DNA binding	4/1218	42/18639	0.0952380952380952	1.45742434904996	0.293637128264427	0.62731081406812
GO:0035198	miRNA binding	4/1218	42/18639	0.0952380952380952	1.45742434904996	0.293637128264427	0.62731081406812
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/1218	29/18639	0.103448275862069	1.58306437914048	0.293826616934205	0.62731081406812
GO:0097472	cyclin-dependent protein kinase activity	3/1218	29/18639	0.103448275862069	1.58306437914048	0.293826616934205	0.62731081406812
GO:0099604	ligand-gated calcium channel activity	3/1218	29/18639	0.103448275862069	1.58306437914048	0.293826616934205	0.62731081406812
GO:1902936	phosphatidylinositol bisphosphate binding	9/1218	111/18639	0.0810810810810811	1.24078018905605	0.300666501235607	0.640603729163211
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/1218	17/18639	0.117647058823529	1.80034772529702	0.306234561016698	0.647183971055533
GO:0005092	GDP-dissociation inhibitor activity	2/1218	17/18639	0.117647058823529	1.80034772529702	0.306234561016698	0.647183971055533
GO:0008484	sulfuric ester hydrolase activity	2/1218	17/18639	0.117647058823529	1.80034772529702	0.306234561016698	0.647183971055533
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/1218	17/18639	0.117647058823529	1.80034772529702	0.306234561016698	0.647183971055533
GO:0008200	ion channel inhibitor activity	4/1218	43/18639	0.0930232558139535	1.42353075953717	0.308656006815114	0.650983578010058
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/1218	30/18639	0.1	1.53029556650246	0.312110934020766	0.652993617470299
GO:0008187	poly-pyrimidine tract binding	3/1218	30/18639	0.1	1.53029556650246	0.312110934020766	0.652993617470299
GO:0031624	ubiquitin conjugating enzyme binding	3/1218	30/18639	0.1	1.53029556650246	0.312110934020766	0.652993617470299
GO:0098918	structural constituent of synapse	3/1218	30/18639	0.1	1.53029556650246	0.312110934020766	0.652993617470299
GO:0140098	catalytic activity, acting on RNA	28/1218	387/18639	0.0723514211886305	1.10719059075114	0.314848907083569	0.657404517990491
GO:0019783	ubiquitin-like protein peptidase activity	10/1218	127/18639	0.078740157480315	1.20495713897832	0.317623605912044	0.661874340463421
GO:0061980	regulatory RNA binding	5/1218	58/18639	0.0862068965517241	1.3192203159504	0.328670471188609	0.673345142152062
GO:0016878	acid-thiol ligase activity	3/1218	31/18639	0.0967741935483871	1.48093119338948	0.330422201115237	0.673345142152062
GO:0070325	lipoprotein particle receptor binding	3/1218	31/18639	0.0967741935483871	1.48093119338948	0.330422201115237	0.673345142152062
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	7/1218	86/18639	0.0813953488372093	1.24558941459503	0.330579555695832	0.673345142152062
GO:0004706	JUN kinase kinase kinase activity	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0008308	voltage-gated monoatomic anion channel activity	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0008409	5'-3' exonuclease activity	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0050811	GABA receptor binding	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0070064	proline-rich region binding	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0098641	cadherin binding involved in cell-cell adhesion	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0099602	neurotransmitter receptor regulator activity	2/1218	18/18639	0.111111111111111	1.70032840722496	0.33086787157472	0.673345142152062
GO:0031593	polyubiquitin modification-dependent protein binding	5/1218	59/18639	0.0847457627118644	1.29686064957836	0.341838455698907	0.692969607280892
GO:0070888	E-box binding	5/1218	59/18639	0.0847457627118644	1.29686064957836	0.341838455698907	0.692969607280892
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	10/1218	130/18639	0.0769230769230769	1.17715043577113	0.343815902240703	0.695627523138167
GO:0008378	galactosyltransferase activity	3/1218	32/18639	0.09375	1.43465209359606	0.348718232347259	0.700794580575597
GO:0022884	macromolecule transmembrane transporter activity	3/1218	32/18639	0.09375	1.43465209359606	0.348718232347259	0.700794580575597
GO:0140142	nucleocytoplasmic carrier activity	3/1218	32/18639	0.09375	1.43465209359606	0.348718232347259	0.700794580575597
GO:0008194	UDP-glycosyltransferase activity	11/1218	145/18639	0.0758620689655172	1.16091387803635	0.349054771934205	0.700794580575597
GO:0001098	basal transcription machinery binding	5/1218	60/18639	0.0833333333333333	1.27524630541872	0.355041914777516	0.702420117772248
GO:0001099	basal RNA polymerase II transcription machinery binding	5/1218	60/18639	0.0833333333333333	1.27524630541872	0.355041914777516	0.702420117772248
GO:0005520	insulin-like growth factor binding	2/1218	19/18639	0.105263157894737	1.61083743842365	0.3552469561147	0.702420117772248
GO:0034987	immunoglobulin receptor binding	2/1218	19/18639	0.105263157894737	1.61083743842365	0.3552469561147	0.702420117772248
GO:0043395	heparan sulfate proteoglycan binding	2/1218	19/18639	0.105263157894737	1.61083743842365	0.3552469561147	0.702420117772248
GO:0050145	nucleoside monophosphate kinase activity	2/1218	19/18639	0.105263157894737	1.61083743842365	0.3552469561147	0.702420117772248
GO:0120227	acyl-CoA binding	2/1218	19/18639	0.105263157894737	1.61083743842365	0.3552469561147	0.702420117772248
GO:0140036	ubiquitin-modified protein reader activity	2/1218	19/18639	0.105263157894737	1.61083743842365	0.3552469561147	0.702420117772248
GO:0008168	methyltransferase activity	15/1218	204/18639	0.0735294117647059	1.12521732831063	0.356140966860696	0.702856652934909
GO:0019239	deaminase activity	3/1218	33/18639	0.0909090909090909	1.39117778772951	0.366959658344635	0.721480006236909
GO:0019956	chemokine binding	3/1218	33/18639	0.0909090909090909	1.39117778772951	0.366959658344635	0.721480006236909
GO:0043495	protein-membrane adaptor activity	4/1218	47/18639	0.0851063829787234	1.30237920553401	0.369205249852232	0.724530603093478
GO:0017022	myosin binding	6/1218	76/18639	0.0789473684210526	1.20812807881773	0.377829967009757	0.733313102429014
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/1218	20/18639	0.1	1.53029556650246	0.379299880566731	0.733313102429014
GO:0015095	magnesium ion transmembrane transporter activity	2/1218	20/18639	0.1	1.53029556650246	0.379299880566731	0.733313102429014
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/1218	20/18639	0.1	1.53029556650246	0.379299880566731	0.733313102429014
GO:0042288	MHC class I protein binding	2/1218	20/18639	0.1	1.53029556650246	0.379299880566731	0.733313102429014
GO:0043024	ribosomal small subunit binding	2/1218	20/18639	0.1	1.53029556650246	0.379299880566731	0.733313102429014
GO:0052745	inositol phosphate phosphatase activity	2/1218	20/18639	0.1	1.53029556650246	0.379299880566731	0.733313102429014
GO:0061608	nuclear import signal receptor activity	2/1218	20/18639	0.1	1.53029556650246	0.379299880566731	0.733313102429014
GO:0032266	phosphatidylinositol-3-phosphate binding	4/1218	48/18639	0.0833333333333333	1.27524630541872	0.384340768130936	0.741685327040105
GO:0030332	cyclin binding	3/1218	34/18639	0.0882352941176471	1.35026079397276	0.38510990662419	0.741798417925562
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/1218	21/18639	0.0952380952380952	1.45742434904996	0.402965182521367	0.769420674044395
GO:0001846	opsonin binding	2/1218	21/18639	0.0952380952380952	1.45742434904996	0.402965182521367	0.769420674044395
GO:0008373	sialyltransferase activity	2/1218	21/18639	0.0952380952380952	1.45742434904996	0.402965182521367	0.769420674044395
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1218	21/18639	0.0952380952380952	1.45742434904996	0.402965182521367	0.769420674044395
GO:0034061	DNA polymerase activity	3/1218	35/18639	0.0857142857142857	1.31168191414497	0.403135161592226	0.769420674044395
GO:0004843	cysteine-type deubiquitinase activity	8/1218	108/18639	0.0740740740740741	1.13355227148331	0.410081243298824	0.78124966789046
GO:0003924	GTPase activity	23/1218	331/18639	0.0694864048338369	1.06334737249416	0.410838530632237	0.781266713989172
GO:0016758	hexosyltransferase activity	14/1218	197/18639	0.0710659898477157	1.08751969193068	0.412394556546584	0.782799849153879
GO:0015605	organophosphate ester transmembrane transporter activity	4/1218	50/18639	0.08	1.22423645320197	0.414455807082452	0.785284687103593
GO:0042562	hormone binding	7/1218	94/18639	0.074468085106383	1.13958180484226	0.417348301239498	0.789050941820194
GO:0016247	channel regulator activity	12/1218	168/18639	0.0714285714285714	1.09306826178747	0.417955144469892	0.789050941820194
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/1218	36/18639	0.0833333333333333	1.27524630541872	0.421004307609001	0.78909963580574
GO:0005484	SNAP receptor activity	3/1218	36/18639	0.0833333333333333	1.27524630541872	0.421004307609001	0.78909963580574
GO:0044390	ubiquitin-like protein conjugating enzyme binding	3/1218	36/18639	0.0833333333333333	1.27524630541872	0.421004307609001	0.78909963580574
GO:0055106	ubiquitin-protein transferase regulator activity	3/1218	36/18639	0.0833333333333333	1.27524630541872	0.421004307609001	0.78909963580574
GO:0005525	GTP binding	26/1218	378/18639	0.0687830687830688	1.05258425209164	0.422167968212795	0.789862650204583
GO:0015377	chloride:monoatomic cation symporter activity	2/1218	22/18639	0.0909090909090909	1.39117778772951	0.426190811689124	0.79030765080541
GO:0034062	5'-3' RNA polymerase activity	2/1218	22/18639	0.0909090909090909	1.39117778772951	0.426190811689124	0.79030765080541
GO:0097747	RNA polymerase activity	2/1218	22/18639	0.0909090909090909	1.39117778772951	0.426190811689124	0.79030765080541
GO:0140035	ubiquitin-like protein reader activity	2/1218	22/18639	0.0909090909090909	1.39117778772951	0.426190811689124	0.79030765080541
GO:0140517	protein-RNA adaptor activity	2/1218	22/18639	0.0909090909090909	1.39117778772951	0.426190811689124	0.79030765080541
GO:0003743	translation initiation factor activity	4/1218	51/18639	0.0784313725490196	1.20023181686468	0.429395706357551	0.793432066260677
GO:0005048	signal sequence binding	4/1218	51/18639	0.0784313725490196	1.20023181686468	0.429395706357551	0.793432066260677
GO:0141108	transporter regulator activity	12/1218	170/18639	0.0705882352941176	1.08020863517821	0.434164754300309	0.80082686128891
GO:0016741	transferase activity, transferring one-carbon groups	15/1218	215/18639	0.0697674418604651	1.06764806965288	0.434946621722892	0.800854097140562
GO:0001618	virus receptor activity	6/1218	81/18639	0.0740740740740741	1.13355227148331	0.437103907716896	0.803409295169788
GO:0023023	MHC protein complex binding	3/1218	37/18639	0.0810810810810811	1.24078018905605	0.438688858161931	0.8049053917769
GO:0030159	signaling receptor complex adaptor activity	4/1218	52/18639	0.0769230769230769	1.17715043577113	0.444232626581938	0.813647126581656
GO:0140272	exogenous protein binding	6/1218	82/18639	0.0731707317073171	1.11972846329449	0.448863044626644	0.819133803472827
GO:0099186	structural constituent of postsynapse	2/1218	23/18639	0.0869565217391304	1.33069179695866	0.448933163940801	0.819133803472827
GO:0008234	cysteine-type peptidase activity	13/1218	187/18639	0.0695187165775401	1.06384183767551	0.450074202617029	0.819133803472827
GO:0043022	ribosome binding	8/1218	112/18639	0.0714285714285714	1.09306826178747	0.450366669725482	0.819133803472827
GO:0042162	telomeric DNA binding	3/1218	38/18639	0.0789473684210526	1.20812807881773	0.456162873824087	0.820598403482035
GO:0042887	amide transmembrane transporter activity	3/1218	38/18639	0.0789473684210526	1.20812807881773	0.456162873824087	0.820598403482035
GO:0005246	calcium channel regulator activity	4/1218	53/18639	0.0754716981132075	1.15494005019054	0.458949533596201	0.820598403482035
GO:0005544	calcium-dependent phospholipid binding	4/1218	53/18639	0.0754716981132075	1.15494005019054	0.458949533596201	0.820598403482035
GO:0140296	general transcription initiation factor binding	4/1218	53/18639	0.0754716981132075	1.15494005019054	0.458949533596201	0.820598403482035
GO:0003777	microtubule motor activity	5/1218	68/18639	0.0735294117647059	1.12521732831063	0.460134654348342	0.820598403482035
GO:0005548	phospholipid transporter activity	5/1218	68/18639	0.0735294117647059	1.12521732831063	0.460134654348342	0.820598403482035
GO:0001540	amyloid-beta binding	6/1218	83/18639	0.072289156626506	1.10623775891744	0.460567874627691	0.820598403482035
GO:0008135	translation factor activity, RNA binding	6/1218	83/18639	0.072289156626506	1.10623775891744	0.460567874627691	0.820598403482035
GO:0030246	carbohydrate binding	19/1218	280/18639	0.0678571428571429	1.0384148486981	0.466628864049475	0.820598403482035
GO:0004622	lysophospholipase activity	2/1218	24/18639	0.0833333333333333	1.27524630541872	0.471156201237949	0.820598403482035
GO:0030552	cAMP binding	2/1218	24/18639	0.0833333333333333	1.27524630541872	0.471156201237949	0.820598403482035
GO:0048027	mRNA 5'-UTR binding	2/1218	24/18639	0.0833333333333333	1.27524630541872	0.471156201237949	0.820598403482035
GO:0051117	ATPase binding	6/1218	84/18639	0.0714285714285714	1.09306826178747	0.472209496825823	0.820598403482035
GO:0180051	translation factor activity	6/1218	84/18639	0.0714285714285714	1.09306826178747	0.472209496825823	0.820598403482035
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	3/1218	39/18639	0.0769230769230769	1.17715043577113	0.47340287134436	0.820598403482035
GO:0017069	snRNA binding	4/1218	54/18639	0.0740740740740741	1.13355227148331	0.47353049965511	0.820598403482035
GO:0099106	ion channel regulator activity	11/1218	160/18639	0.06875	1.05207820197044	0.475863461991969	0.820598403482035
GO:0101005	deubiquitinase activity	8/1218	115/18639	0.0695652173913043	1.06455343756693	0.480287104724315	0.820598403482035
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0003796	lysozyme activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0004955	prostaglandin receptor activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0005131	growth hormone receptor binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0005528	FK506 binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0008190	eukaryotic initiation factor 4E binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0008239	dipeptidyl-peptidase activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0015203	polyamine transmembrane transporter activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0031419	cobalamin binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0031434	mitogen-activated protein kinase kinase binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0031996	thioesterase binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0032356	oxidized DNA binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0035256	G protein-coupled glutamate receptor binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0043208	glycosphingolipid binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0045322	unmethylated CpG binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0051864	histone H3K36 demethylase activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0070097	delta-catenin binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0070513	death domain binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:1990757	ubiquitin ligase activator activity	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:1990763	arrestin family protein binding	1/1218	10/18639	0.1	1.53029556650246	0.491335544633263	0.820598403482035
GO:0000030	mannosyltransferase activity	2/1218	25/18639	0.08	1.22423645320197	0.492830650367084	0.820598403482035
GO:0001848	complement binding	2/1218	25/18639	0.08	1.22423645320197	0.492830650367084	0.820598403482035
GO:0015271	outward rectifier potassium channel activity	2/1218	25/18639	0.08	1.22423645320197	0.492830650367084	0.820598403482035
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/1218	25/18639	0.08	1.22423645320197	0.492830650367084	0.820598403482035
GO:0017056	structural constituent of nuclear pore	2/1218	25/18639	0.08	1.22423645320197	0.492830650367084	0.820598403482035
GO:0047617	fatty acyl-CoA hydrolase activity	2/1218	25/18639	0.08	1.22423645320197	0.492830650367084	0.820598403482035
GO:0008238	exopeptidase activity	7/1218	102/18639	0.0686274509803922	1.05020283975659	0.503093751404508	0.836145193223286
GO:0140318	protein transporter activity	3/1218	41/18639	0.0731707317073171	1.11972846329449	0.507098568434472	0.836145193223286
GO:0004435	phosphatidylinositol phospholipase C activity	2/1218	26/18639	0.0769230769230769	1.17715043577113	0.513933273949507	0.836145193223286
GO:0005160	transforming growth factor beta receptor binding	2/1218	26/18639	0.0769230769230769	1.17715043577113	0.513933273949507	0.836145193223286
GO:0008143	poly(A) binding	2/1218	26/18639	0.0769230769230769	1.17715043577113	0.513933273949507	0.836145193223286
GO:0016289	acyl-CoA hydrolase activity	2/1218	26/18639	0.0769230769230769	1.17715043577113	0.513933273949507	0.836145193223286
GO:0050750	low-density lipoprotein particle receptor binding	2/1218	26/18639	0.0769230769230769	1.17715043577113	0.513933273949507	0.836145193223286
GO:0051087	protein-folding chaperone binding	9/1218	134/18639	0.0671641791044776	1.02781045511359	0.515661216054333	0.836145193223286
GO:0015932	nucleobase-containing compound transmembrane transporter activity	4/1218	57/18639	0.0701754385964912	1.07389162561576	0.516314811500429	0.836145193223286
GO:0008307	structural constituent of muscle	3/1218	42/18639	0.0714285714285714	1.09306826178747	0.523518679216783	0.836145193223286
GO:0051879	Hsp90 protein binding	3/1218	42/18639	0.0714285714285714	1.09306826178747	0.523518679216783	0.836145193223286
GO:0004954	prostanoid receptor activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0008172	S-methyltransferase activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0008432	JUN kinase binding	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0008503	benzodiazepine receptor activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0008526	phosphatidylinositol transfer activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0010854	adenylate cyclase regulator activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0019206	nucleoside kinase activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0034511	U3 snoRNA binding	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0034713	type I transforming growth factor beta receptor binding	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0042608	T cell receptor binding	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0043522	leucine zipper domain binding	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0045294	alpha-catenin binding	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0047676	arachidonate-CoA ligase activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0140537	transcription regulator activator activity	1/1218	11/18639	0.0909090909090909	1.39117778772951	0.524593009158287	0.836145193223286
GO:0016874	ligase activity	11/1218	167/18639	0.0658682634730539	1.00797911566031	0.533876645810413	0.84667957640912
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/1218	27/18639	0.0740740740740741	1.13355227148331	0.534446207714186	0.84667957640912
GO:0008320	protein transmembrane transporter activity	2/1218	27/18639	0.0740740740740741	1.13355227148331	0.534446207714186	0.84667957640912
GO:0016405	CoA-ligase activity	2/1218	27/18639	0.0740740740740741	1.13355227148331	0.534446207714186	0.84667957640912
GO:0003684	damaged DNA binding	5/1218	74/18639	0.0675675675675676	1.03398349088004	0.535622898762458	0.847258039860616
GO:0019001	guanyl nucleotide binding	26/1218	400/18639	0.065	0.994692118226601	0.540814026814517	0.849381440789979
GO:0032561	guanyl ribonucleotide binding	26/1218	400/18639	0.065	0.994692118226601	0.540814026814517	0.849381440789979
GO:0004857	enzyme inhibitor activity	27/1218	416/18639	0.0649038461538462	0.993220680181887	0.543707358442428	0.849381440789979
GO:0016829	lyase activity	13/1218	200/18639	0.065	0.994692118226601	0.549086276148819	0.849381440789979
GO:0051393	alpha-actinin binding	2/1218	28/18639	0.0714285714285714	1.09306826178747	0.554356358497384	0.849381440789979
GO:0016790	thiolester hydrolase activity	3/1218	44/18639	0.0681818181818182	1.04338334079713	0.555429922768649	0.849381440789979
GO:0019205	nucleobase-containing compound kinase activity	3/1218	44/18639	0.0681818181818182	1.04338334079713	0.555429922768649	0.849381440789979
GO:0004000	adenosine deaminase activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0004126	cytidine deaminase activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0005049	nuclear export signal receptor activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0005165	neurotrophin receptor binding	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0005436	sodium:phosphate symporter activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0005527	macrolide binding	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0010853	cyclase activator activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0015132	prostaglandin transmembrane transporter activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0015166	polyol transmembrane transporter activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0016423	tRNA (guanine) methyltransferase activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0017166	vinculin binding	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0035197	siRNA binding	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0035497	cAMP response element binding	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0045295	gamma-catenin binding	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:1990817	poly(A) RNA polymerase activity	1/1218	12/18639	0.0833333333333333	1.27524630541872	0.555677705037888	0.849381440789979
GO:0051536	iron-sulfur cluster binding	5/1218	76/18639	0.0657894736842105	1.00677339901478	0.559707942135635	0.854291069575442
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/1218	61/18639	0.0655737704918033	1.00347250262457	0.570678373340853	0.854985516668358
GO:0046915	transition metal ion transmembrane transporter activity	3/1218	45/18639	0.0666666666666667	1.02019704433498	0.570897383883463	0.854985516668358
GO:0003724	RNA helicase activity	5/1218	77/18639	0.0649350649350649	0.993698419806794	0.571513022090211	0.854985516668358
GO:0051540	metal cluster binding	5/1218	77/18639	0.0649350649350649	0.993698419806794	0.571513022090211	0.854985516668358
GO:0004181	metallocarboxypeptidase activity	2/1218	29/18639	0.0689655172413793	1.05537625276032	0.573654857872435	0.854985516668358
GO:0004629	phospholipase C activity	2/1218	29/18639	0.0689655172413793	1.05537625276032	0.573654857872435	0.854985516668358
GO:0035250	UDP-galactosyltransferase activity	2/1218	29/18639	0.0689655172413793	1.05537625276032	0.573654857872435	0.854985516668358
GO:0043236	laminin binding	2/1218	29/18639	0.0689655172413793	1.05537625276032	0.573654857872435	0.854985516668358
GO:0051861	glycolipid binding	2/1218	29/18639	0.0689655172413793	1.05537625276032	0.573654857872435	0.854985516668358
GO:0004620	phospholipase activity	7/1218	109/18639	0.0642201834862385	0.982758620689655	0.574467197834602	0.854985516668358
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0008035	high-density lipoprotein particle binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0008253	5'-nucleotidase activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0008417	fucosyltransferase activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0009982	pseudouridine synthase activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0017154	semaphorin receptor activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0019855	calcium channel inhibitor activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0030955	potassium ion binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0031432	titin binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0035325	Toll-like receptor binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0035673	oligopeptide transmembrane transporter activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0045159	myosin II binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0051011	microtubule minus-end binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0071714	icosanoid transmembrane transporter activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0089720	caspase binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0097157	pre-mRNA intronic binding	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0140666	annealing activity	1/1218	13/18639	0.0769230769230769	1.17715043577113	0.584731474043303	0.854985516668358
GO:0031210	phosphatidylcholine binding	2/1218	30/18639	0.0666666666666667	1.02019704433498	0.592336566718982	0.863686278847231
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/1218	30/18639	0.0666666666666667	1.02019704433498	0.592336566718982	0.863686278847231
GO:0008186	ATP-dependent activity, acting on RNA	5/1218	79/18639	0.0632911392405063	0.968541497786369	0.594616856045606	0.865801949388581
GO:0005200	structural constituent of cytoskeleton	7/1218	112/18639	0.0625	0.956434729064039	0.603528765782359	0.871500585602826
GO:0005164	tumor necrosis factor receptor binding	2/1218	31/18639	0.0645161290322581	0.987287462259654	0.610399626415792	0.871500585602826
GO:0005452	solute:inorganic anion antiporter activity	2/1218	31/18639	0.0645161290322581	0.987287462259654	0.610399626415792	0.871500585602826
GO:0047499	calcium-independent phospholipase A2 activity	2/1218	31/18639	0.0645161290322581	0.987287462259654	0.610399626415792	0.871500585602826
GO:0070273	phosphatidylinositol-4-phosphate binding	2/1218	31/18639	0.0645161290322581	0.987287462259654	0.610399626415792	0.871500585602826
GO:0004065	arylsulfatase activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0008494	translation activator activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0015926	glucosidase activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0061783	peptidoglycan muralytic activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0070742	C2H2 zinc finger domain binding	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0071933	Arp2/3 complex binding	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0098599	palmitoyl hydrolase activity	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:1990825	sequence-specific mRNA binding	1/1218	14/18639	0.0714285714285714	1.09306826178747	0.611886905408881	0.871500585602826
GO:0016298	lipase activity	8/1218	130/18639	0.0615384615384615	0.9417203486169	0.621014477065273	0.881202289054645
GO:0030515	snoRNA binding	2/1218	32/18639	0.0625	0.956434729064039	0.627845052687028	0.881202289054645
GO:0031369	translation initiation factor binding	2/1218	32/18639	0.0625	0.956434729064039	0.627845052687028	0.881202289054645
GO:0047498	calcium-dependent phospholipase A2 activity	2/1218	32/18639	0.0625	0.956434729064039	0.627845052687028	0.881202289054645
GO:0070717	poly-purine tract binding	2/1218	32/18639	0.0625	0.956434729064039	0.627845052687028	0.881202289054645
GO:0071813	lipoprotein particle binding	2/1218	32/18639	0.0625	0.956434729064039	0.627845052687028	0.881202289054645
GO:0071814	protein-lipid complex binding	2/1218	32/18639	0.0625	0.956434729064039	0.627845052687028	0.881202289054645
GO:0004089	carbonate dehydratase activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0004129	cytochrome-c oxidase activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0004953	icosanoid receptor activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0005041	low-density lipoprotein particle receptor activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0008252	nucleotidase activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0010181	FMN binding	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0031005	filamin binding	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0031386	protein tag activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0047372	monoacylglycerol lipase activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0048531	beta-1,3-galactosyltransferase activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0061578	K63-linked deubiquitinase activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0141047	molecular tag activity	1/1218	15/18639	0.0666666666666667	1.02019704433498	0.637267938923618	0.881202289054645
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/1218	33/18639	0.0606060606060606	0.927451858486341	0.644676368451053	0.888126135916865
GO:0140416	transcription regulator inhibitor activity	2/1218	33/18639	0.0606060606060606	0.927451858486341	0.644676368451053	0.888126135916865
GO:0016597	amino acid binding	3/1218	51/18639	0.0588235294117647	0.900173862648508	0.656382268605218	0.888126135916865
GO:0016830	carbon-carbon lyase activity	3/1218	51/18639	0.0588235294117647	0.900173862648508	0.656382268605218	0.888126135916865
GO:0022853	active monoatomic ion transmembrane transporter activity	7/1218	118/18639	0.0593220338983051	0.907802454704851	0.658355515638141	0.888126135916865
GO:0008175	tRNA methyltransferase activity	2/1218	34/18639	0.0588235294117647	0.900173862648508	0.660899272315232	0.888126135916865
GO:0015020	glucuronosyltransferase activity	2/1218	34/18639	0.0588235294117647	0.900173862648508	0.660899272315232	0.888126135916865
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1218	34/18639	0.0588235294117647	0.900173862648508	0.660899272315232	0.888126135916865
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1218	34/18639	0.0588235294117647	0.900173862648508	0.660899272315232	0.888126135916865
GO:0016831	carboxy-lyase activity	2/1218	34/18639	0.0588235294117647	0.900173862648508	0.660899272315232	0.888126135916865
GO:0000062	fatty-acyl-CoA binding	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0003688	DNA replication origin binding	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0005149	interleukin-1 receptor binding	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0005521	lamin binding	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0008142	oxysterol binding	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0015562	efflux transmembrane transporter activity	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0019841	retinol binding	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0022858	alanine transmembrane transporter activity	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/1218	16/18639	0.0625	0.956434729064039	0.660990428742724	0.888126135916865
GO:0008237	metallopeptidase activity	11/1218	184/18639	0.0597826086956522	0.914850610409081	0.663487217307085	0.890335031964777
GO:0042277	peptide binding	15/1218	249/18639	0.0602409638554217	0.921864799097869	0.665576544750408	0.8919921857759
GO:0004623	phospholipase A2 activity	2/1218	35/18639	0.0571428571428571	0.874454609429979	0.676521339631778	0.900532611081474
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0008429	phosphatidylethanolamine binding	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0016805	dipeptidase activity	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0019198	transmembrane receptor protein phosphatase activity	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0030169	low-density lipoprotein particle binding	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0030548	acetylcholine receptor regulator activity	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0031489	myosin V binding	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0045125	bioactive lipid receptor activity	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0045236	CXCR chemokine receptor binding	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0051787	misfolded protein binding	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:1901567	fatty acid derivative binding	1/1218	17/18639	0.0588235294117647	0.900173862648508	0.683162670475601	0.900532611081474
GO:0045505	dynein intermediate chain binding	2/1218	36/18639	0.0555555555555556	0.850164203612479	0.691551753280176	0.909956923804746
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/1218	54/18639	0.0555555555555556	0.850164203612479	0.694259006329882	0.909956923804746
GO:0050661	NADP binding	3/1218	54/18639	0.0555555555555556	0.850164203612479	0.694259006329882	0.909956923804746
GO:0008013	beta-catenin binding	6/1218	106/18639	0.0566037735849057	0.866205037642904	0.699055692176187	0.909956923804746
GO:0046982	protein heterodimerization activity	22/1218	369/18639	0.0596205962059621	0.912371340462173	0.703705065594989	0.909956923804746
GO:0000900	mRNA regulatory element binding translation repressor activity	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0003746	translation elongation factor activity	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0005372	water transmembrane transporter activity	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0008525	phosphatidylcholine transporter activity	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0017075	syntaxin-1 binding	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0017128	phospholipid scramblase activity	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0030228	lipoprotein particle receptor activity	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0070628	proteasome binding	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:1901611	phosphatidylglycerol binding	1/1218	18/18639	0.0555555555555556	0.850164203612479	0.703885893940359	0.909956923804746
GO:0030551	cyclic nucleotide binding	2/1218	37/18639	0.0540540540540541	0.827186792704034	0.706001061572648	0.909956923804746
GO:0042805	actinin binding	2/1218	37/18639	0.0540540540540541	0.827186792704034	0.706001061572648	0.909956923804746
GO:0043394	proteoglycan binding	2/1218	37/18639	0.0540540540540541	0.827186792704034	0.706001061572648	0.909956923804746
GO:0004521	RNA endonuclease activity	4/1218	73/18639	0.0547945205479452	0.838518118631487	0.710939581664207	0.915192260490052
GO:0005109	frizzled binding	2/1218	38/18639	0.0526315789473684	0.805418719211823	0.719880960892012	0.923078156072888
GO:0043531	ADP binding	2/1218	38/18639	0.0526315789473684	0.805418719211823	0.719880960892012	0.923078156072888
GO:0008301	DNA binding, bending	1/1218	19/18639	0.0526315789473684	0.805418719211823	0.723254723819562	0.923078156072888
GO:0015245	fatty acid transmembrane transporter activity	1/1218	19/18639	0.0526315789473684	0.805418719211823	0.723254723819562	0.923078156072888
GO:0016918	retinal binding	1/1218	19/18639	0.0526315789473684	0.805418719211823	0.723254723819562	0.923078156072888
GO:0030506	ankyrin binding	1/1218	19/18639	0.0526315789473684	0.805418719211823	0.723254723819562	0.923078156072888
GO:0031420	alkali metal ion binding	1/1218	19/18639	0.0526315789473684	0.805418719211823	0.723254723819562	0.923078156072888
GO:0044183	protein folding chaperone	4/1218	75/18639	0.0533333333333333	0.81615763546798	0.730716291461157	0.93009122880405
GO:0004866	endopeptidase inhibitor activity	9/1218	161/18639	0.0559006211180124	0.855444726616284	0.732344914065344	0.93009122880405
GO:0004222	metalloendopeptidase activity	6/1218	110/18639	0.0545454545454545	0.834706672637707	0.732384012603826	0.93009122880405
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/1218	39/18639	0.0512820512820513	0.78476695718075	0.733204100867561	0.93009122880405
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/1218	39/18639	0.0512820512820513	0.78476695718075	0.733204100867561	0.93009122880405
GO:0010851	cyclase regulator activity	1/1218	20/18639	0.05	0.765147783251232	0.741357610306553	0.938154357769747
GO:0016408	C-acyltransferase activity	1/1218	20/18639	0.05	0.765147783251232	0.741357610306553	0.938154357769747
GO:0015036	disulfide oxidoreductase activity	2/1218	40/18639	0.05	0.765147783251232	0.745983910075346	0.940191721960128
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/1218	40/18639	0.05	0.765147783251232	0.745983910075346	0.940191721960128
GO:0050997	quaternary ammonium group binding	2/1218	40/18639	0.05	0.765147783251232	0.745983910075346	0.940191721960128
GO:0001786	phosphatidylserine binding	3/1218	59/18639	0.0508474576271186	0.778116389747015	0.750219686554426	0.940191721960128
GO:0004879	nuclear receptor activity	3/1218	59/18639	0.0508474576271186	0.778116389747015	0.750219686554426	0.940191721960128
GO:0015459	potassium channel regulator activity	3/1218	59/18639	0.0508474576271186	0.778116389747015	0.750219686554426	0.940191721960128
GO:0004867	serine-type endopeptidase inhibitor activity	5/1218	95/18639	0.0526315789473684	0.805418719211823	0.751788223189966	0.940191721960128
GO:0015085	calcium ion transmembrane transporter activity	8/1218	147/18639	0.054421768707483	0.832813913742837	0.752087415740325	0.940191721960128
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	10/1218	181/18639	0.0552486187845304	0.845467163813515	0.752204502293234	0.940191721960128
GO:0042287	MHC protein binding	2/1218	41/18639	0.0487804878048781	0.746485642196324	0.758234440415904	0.940191721960128
GO:0005123	death receptor binding	1/1218	21/18639	0.0476190476190476	0.728712174524982	0.758277231695812	0.940191721960128
GO:0005248	voltage-gated sodium channel activity	1/1218	21/18639	0.0476190476190476	0.728712174524982	0.758277231695812	0.940191721960128
GO:0009975	cyclase activity	1/1218	21/18639	0.0476190476190476	0.728712174524982	0.758277231695812	0.940191721960128
GO:0010314	phosphatidylinositol-5-phosphate binding	1/1218	21/18639	0.0476190476190476	0.728712174524982	0.758277231695812	0.940191721960128
GO:0019200	carbohydrate kinase activity	1/1218	21/18639	0.0476190476190476	0.728712174524982	0.758277231695812	0.940191721960128
GO:0051428	peptide hormone receptor binding	1/1218	21/18639	0.0476190476190476	0.728712174524982	0.758277231695812	0.940191721960128
GO:0070182	DNA polymerase binding	1/1218	21/18639	0.0476190476190476	0.728712174524982	0.758277231695812	0.940191721960128
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3/1218	60/18639	0.05	0.765147783251232	0.760367809189268	0.940549754494781
GO:0098531	ligand-modulated transcription factor activity	3/1218	60/18639	0.05	0.765147783251232	0.760367809189268	0.940549754494781
GO:0008509	monoatomic anion transmembrane transporter activity	8/1218	149/18639	0.0536912751677852	0.821635203491255	0.765163199216662	0.945361396428633
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	15/1218	268/18639	0.0559701492537313	0.856508712594662	0.768768915337182	0.946818514168196
GO:0061135	endopeptidase regulator activity	10/1218	184/18639	0.0543478260869565	0.831682373099165	0.769847902123394	0.946818514168196
GO:0004520	DNA endonuclease activity	2/1218	42/18639	0.0476190476190476	0.728712174524982	0.76997022847586	0.946818514168196
GO:0016859	cis-trans isomerase activity	2/1218	42/18639	0.0476190476190476	0.728712174524982	0.76997022847586	0.946818514168196
GO:0031683	G-protein beta/gamma-subunit complex binding	1/1218	22/18639	0.0454545454545455	0.695588893864756	0.77409087074375	0.948533883869102
GO:0033691	sialic acid binding	1/1218	22/18639	0.0454545454545455	0.695588893864756	0.77409087074375	0.948533883869102
GO:0061133	endopeptidase activator activity	1/1218	22/18639	0.0454545454545455	0.695588893864756	0.77409087074375	0.948533883869102
GO:0042626	ATPase-coupled transmembrane transporter activity	5/1218	98/18639	0.0510204081632653	0.78076304413391	0.775506127053346	0.949154040613943
GO:0008375	acetylglucosaminyltransferase activity	2/1218	43/18639	0.0465116279069767	0.711765379768587	0.781206172321175	0.954960007812732
GO:0030414	peptidase inhibitor activity	9/1218	169/18639	0.0532544378698225	0.814950301687702	0.782079316743186	0.954960007812732
GO:0004175	endopeptidase activity	23/1218	405/18639	0.0567901234567901	0.869056741470535	0.787119808404251	0.95654016287323
GO:0008171	O-methyltransferase activity	1/1218	23/18639	0.0434782608695652	0.665345898479332	0.78887076650752	0.95654016287323
GO:0016493	C-C chemokine receptor activity	1/1218	23/18639	0.0434782608695652	0.665345898479332	0.78887076650752	0.95654016287323
GO:0016849	phosphorus-oxygen lyase activity	1/1218	23/18639	0.0434782608695652	0.665345898479332	0.78887076650752	0.95654016287323
GO:0017134	fibroblast growth factor binding	1/1218	23/18639	0.0434782608695652	0.665345898479332	0.78887076650752	0.95654016287323
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/1218	23/18639	0.0434782608695652	0.665345898479332	0.78887076650752	0.95654016287323
GO:0030547	signaling receptor inhibitor activity	2/1218	44/18639	0.0454545454545455	0.695588893864756	0.791957422299866	0.9566239255271
GO:0004536	DNA nuclease activity	3/1218	64/18639	0.046875	0.71732604679803	0.797653672030055	0.9566239255271
GO:0005126	cytokine receptor binding	15/1218	275/18639	0.0545454545454545	0.834706672637707	0.800738281452844	0.9566239255271
GO:0042605	peptide antigen binding	2/1218	45/18639	0.0444444444444444	0.680131362889984	0.802239284551792	0.9566239255271
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0004806	triacylglycerol lipase activity	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0015295	solute:proton symporter activity	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0019957	C-C chemokine binding	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0050699	WW domain binding	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0070840	dynein complex binding	1/1218	24/18639	0.0416666666666667	0.63762315270936	0.802684443258371	0.9566239255271
GO:0051082	unfolded protein binding	6/1218	121/18639	0.0495867768595041	0.758824247852461	0.810236696126976	0.962125648307921
GO:0005253	monoatomic anion channel activity	5/1218	103/18639	0.0485436893203883	0.742861925486633	0.811111849106702	0.962125648307921
GO:0004180	carboxypeptidase activity	2/1218	46/18639	0.0434782608695652	0.665345898479332	0.812067136033243	0.962125648307921
GO:0001217	DNA-binding transcription repressor activity	15/1218	278/18639	0.0539568345323741	0.825699046673991	0.813430167511711	0.962125648307921
GO:0005537	D-mannose binding	1/1218	25/18639	0.04	0.612118226600985	0.815595017962175	0.962125648307921
GO:0008483	transaminase activity	1/1218	25/18639	0.04	0.612118226600985	0.815595017962175	0.962125648307921
GO:0015645	fatty acid ligase activity	1/1218	25/18639	0.04	0.612118226600985	0.815595017962175	0.962125648307921
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/1218	25/18639	0.04	0.612118226600985	0.815595017962175	0.962125648307921
GO:0120515	fatty acid-CoA ligase activity	1/1218	25/18639	0.04	0.612118226600985	0.815595017962175	0.962125648307921
GO:0005504	fatty acid binding	2/1218	47/18639	0.0425531914893617	0.651189602767006	0.821456349965471	0.964159790503201
GO:0050840	extracellular matrix binding	3/1218	67/18639	0.0447761194029851	0.68520697007573	0.822324547835453	0.964159790503201
GO:0001637	G protein-coupled chemoattractant receptor activity	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0004950	chemokine receptor activity	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0008198	ferrous iron binding	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0030247	polysaccharide binding	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0030507	spectrin binding	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0034237	protein kinase A regulatory subunit binding	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0120014	phospholipid transfer activity	1/1218	26/18639	0.0384615384615385	0.588575217885563	0.827661487722681	0.964159790503201
GO:0008081	phosphoric diester hydrolase activity	4/1218	87/18639	0.0459770114942529	0.70358416850688	0.828401659081774	0.964159790503201
GO:0019955	cytokine binding	7/1218	144/18639	0.0486111111111111	0.74389367816092	0.838104180593743	0.971068906294609
GO:0005385	zinc ion transmembrane transporter activity	1/1218	27/18639	0.037037037037037	0.566776135741653	0.838938998492239	0.971068906294609
GO:0015252	proton channel activity	1/1218	27/18639	0.037037037037037	0.566776135741653	0.838938998492239	0.971068906294609
GO:0035255	ionotropic glutamate receptor binding	1/1218	27/18639	0.037037037037037	0.566776135741653	0.838938998492239	0.971068906294609
GO:0016853	isomerase activity	9/1218	180/18639	0.05	0.765147783251232	0.838988652756454	0.971068906294609
GO:0016782	transferase activity, transferring sulphur-containing groups	3/1218	70/18639	0.0428571428571429	0.655840957072484	0.844381423296113	0.975354385897619
GO:0004519	endonuclease activity	6/1218	127/18639	0.047244094488189	0.72297428338699	0.844559736447746	0.975354385897619
GO:0032813	tumor necrosis factor receptor superfamily binding	2/1218	50/18639	0.04	0.612118226600985	0.847144533791399	0.975639358092077
GO:0016866	intramolecular transferase activity	1/1218	28/18639	0.0357142857142857	0.546534130893737	0.849479096269826	0.975639358092077
GO:0046625	sphingolipid binding	1/1218	28/18639	0.0357142857142857	0.546534130893737	0.849479096269826	0.975639358092077
GO:0050698	proteoglycan sulfotransferase activity	1/1218	28/18639	0.0357142857142857	0.546534130893737	0.849479096269826	0.975639358092077
GO:0051959	dynein light intermediate chain binding	1/1218	28/18639	0.0357142857142857	0.546534130893737	0.849479096269826	0.975639358092077
GO:0140299	molecular sensor activity	3/1218	71/18639	0.0422535211267606	0.646603760493998	0.851186996404322	0.976526620050673
GO:0106222	lncRNA binding	1/1218	29/18639	0.0344827586206897	0.52768812638016	0.859329961926876	0.984786476675805
GO:0015215	nucleotide transmembrane transporter activity	1/1218	30/18639	0.0333333333333333	0.510098522167488	0.868536630727148	0.989488742940048
GO:0016769	transferase activity, transferring nitrogenous groups	1/1218	30/18639	0.0333333333333333	0.510098522167488	0.868536630727148	0.989488742940048
GO:0008146	sulfotransferase activity	2/1218	53/18639	0.0377358490566038	0.577470025095269	0.86942595447228	0.989488742940048
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/1218	53/18639	0.0377358490566038	0.577470025095269	0.86942595447228	0.989488742940048
GO:0017046	peptide hormone binding	2/1218	53/18639	0.0377358490566038	0.577470025095269	0.86942595447228	0.989488742940048
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/1218	53/18639	0.0377358490566038	0.577470025095269	0.86942595447228	0.989488742940048
GO:0048029	monosaccharide binding	3/1218	74/18639	0.0405405405405405	0.620390094528026	0.870067687757628	0.989488742940048
GO:0008327	methyl-CpG binding	1/1218	31/18639	0.032258064516129	0.493643731129827	0.877141197537526	0.996447671631314
GO:0061134	peptidase regulator activity	11/1218	226/18639	0.0486725663716814	0.744834125288809	0.879665789503261	0.998229439392831
GO:0004896	cytokine receptor activity	4/1218	96/18639	0.0416666666666667	0.63762315270936	0.880645092738631	0.998255675156493
GO:0140313	molecular sequestering activity	2/1218	55/18639	0.0363636363636364	0.556471115091805	0.882578326395359	0.998529638902999
GO:0015294	solute:monoatomic cation symporter activity	5/1218	116/18639	0.0431034482758621	0.6596101579752	0.882799671175735	0.998529638902999
GO:0015106	bicarbonate transmembrane transporter activity	1/1218	32/18639	0.03125	0.47821736453202	0.885183008661736	0.999060606532813
GO:0043425	bHLH transcription factor binding	1/1218	32/18639	0.03125	0.47821736453202	0.885183008661736	0.999060606532813
GO:0019212	phosphatase inhibitor activity	2/1218	56/18639	0.0357142857142857	0.546534130893737	0.888684772084453	0.999999999820103
GO:0170055	lipid transmembrane transporter activity	2/1218	56/18639	0.0357142857142857	0.546534130893737	0.888684772084453	0.999999999820103
GO:0140375	immune receptor activity	7/1218	156/18639	0.0448717948717949	0.686671087533157	0.89075149068619	0.999999999820103
GO:0140311	protein sequestering activity	1/1218	33/18639	0.0303030303030303	0.463725929243171	0.89269884116832	0.999999999820103
GO:0016504	peptidase activator activity	2/1218	57/18639	0.0350877192982456	0.536945812807882	0.894495396621855	0.999999999820103
GO:0140101	catalytic activity, acting on a tRNA	6/1218	139/18639	0.0431654676258993	0.660559237339193	0.898059514659583	0.999999999820103
GO:0015035	protein-disulfide reductase activity	1/1218	34/18639	0.0294117647058824	0.450086931324254	0.899723070527504	0.999999999820103
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/1218	34/18639	0.0294117647058824	0.450086931324254	0.899723070527504	0.999999999820103
GO:0051427	hormone receptor binding	1/1218	34/18639	0.0294117647058824	0.450086931324254	0.899723070527504	0.999999999820103
GO:0036002	pre-mRNA binding	2/1218	59/18639	0.0338983050847458	0.518744259831343	0.905278994576919	0.999999999820103
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/1218	122/18639	0.040983606557377	0.627170314140354	0.907129890489694	0.999999999820103
GO:0004190	aspartic-type endopeptidase activity	1/1218	36/18639	0.0277777777777778	0.42508210180624	0.912423143719652	0.999999999820103
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/1218	36/18639	0.0277777777777778	0.42508210180624	0.912423143719652	0.999999999820103
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/1218	36/18639	0.0277777777777778	0.42508210180624	0.912423143719652	0.999999999820103
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/1218	36/18639	0.0277777777777778	0.42508210180624	0.912423143719652	0.999999999820103
GO:0015026	coreceptor activity	2/1218	61/18639	0.0327868852459016	0.501736251312283	0.915024969301399	0.999999999820103
GO:0030280	structural constituent of skin epidermis	1/1218	37/18639	0.027027027027027	0.413593396352017	0.918157090445957	0.999999999820103
GO:0070001	aspartic-type peptidase activity	1/1218	37/18639	0.027027027027027	0.413593396352017	0.918157090445957	0.999999999820103
GO:0015103	inorganic anion transmembrane transporter activity	7/1218	165/18639	0.0424242424242424	0.649216300940439	0.92006149750448	0.999999999820103
GO:0004497	monooxygenase activity	4/1218	106/18639	0.0377358490566038	0.577470025095269	0.921948410508896	0.999999999820103
GO:0015399	primary active transmembrane transporter activity	7/1218	166/18639	0.0421686746987952	0.645305359368509	0.922854652882378	0.999999999820103
GO:0005501	retinoid binding	1/1218	38/18639	0.0263157894736842	0.402709359605911	0.923515904758226	0.999999999820103
GO:0019840	isoprenoid binding	1/1218	38/18639	0.0263157894736842	0.402709359605911	0.923515904758226	0.999999999820103
GO:0003730	mRNA 3'-UTR binding	12/1218	262/18639	0.0458015267175573	0.70089873274922	0.927822770522075	0.999999999820103
GO:0005201	extracellular matrix structural constituent	7/1218	168/18639	0.0416666666666667	0.63762315270936	0.928187278476222	0.999999999820103
GO:0038024	cargo receptor activity	2/1218	65/18639	0.0307692307692308	0.47086017430845	0.931756969452262	0.999999999820103
GO:0140662	ATP-dependent protein folding chaperone	1/1218	40/18639	0.025	0.382573891625616	0.93320462807373	0.999999999820103
GO:0033218	amide binding	11/1218	247/18639	0.0445344129554656	0.681508147025388	0.935069219463205	0.999999999820103
GO:0005262	calcium channel activity	5/1218	131/18639	0.0381679389312977	0.584082277291016	0.93534107975587	0.999999999820103
GO:0046906	tetrapyrrole binding	6/1218	152/18639	0.0394736842105263	0.604064039408867	0.93741137425324	0.999999999820103
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/1218	41/18639	0.024390243902439	0.373242821098162	0.937578882765175	0.999999999820103
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/1218	41/18639	0.024390243902439	0.373242821098162	0.937578882765175	0.999999999820103
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	5/1218	132/18639	0.0378787878787879	0.579657411553963	0.937946945097655	0.999999999820103
GO:0008173	RNA methyltransferase activity	2/1218	67/18639	0.0298507462686567	0.456804646717153	0.93890433782734	0.999999999820103
GO:0016500	protein-hormone receptor activity	2/1218	67/18639	0.0298507462686567	0.456804646717153	0.93890433782734	0.999999999820103
GO:0072341	modified amino acid binding	3/1218	91/18639	0.032967032967033	0.504493043901911	0.941995897658862	0.999999999820103
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	2/1218	68/18639	0.0294117647058824	0.450086931324254	0.942205754158049	0.999999999820103
GO:0140223	general transcription initiation factor activity	2/1218	68/18639	0.0294117647058824	0.450086931324254	0.942205754158049	0.999999999820103
GO:0008236	serine-type peptidase activity	8/1218	194/18639	0.0412371134020619	0.631049718145346	0.943168084985563	0.999999999820103
GO:0052689	carboxylic ester hydrolase activity	3/1218	92/18639	0.0326086956521739	0.499009423859499	0.944779809845779	0.999999999820103
GO:0005245	voltage-gated calcium channel activity	1/1218	43/18639	0.0232558139534884	0.355882689884294	0.94548739220922	0.999999999820103
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1218	43/18639	0.0232558139534884	0.355882689884294	0.94548739220922	0.999999999820103
GO:0004252	serine-type endopeptidase activity	7/1218	176/18639	0.0397727272727273	0.608640282131661	0.946422491372863	0.999999999820103
GO:0019838	growth factor binding	5/1218	136/18639	0.0367647058823529	0.562608664155317	0.947451779944717	0.999999999820103
GO:0003954	NADH dehydrogenase activity	1/1218	44/18639	0.0227272727272727	0.347794446932378	0.949057856625716	0.999999999820103
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/1218	44/18639	0.0227272727272727	0.347794446932378	0.949057856625716	0.999999999820103
GO:0009055	electron transfer activity	4/1218	116/18639	0.0344827586206897	0.52768812638016	0.949939551462646	0.999999999820103
GO:0017171	serine hydrolase activity	8/1218	198/18639	0.0404040404040404	0.618301238990894	0.950703183803511	0.999999999820103
GO:0008009	chemokine activity	1/1218	45/18639	0.0222222222222222	0.340065681444992	0.952394642354669	0.999999999820103
GO:0042379	chemokine receptor binding	2/1218	72/18639	0.0277777777777778	0.42508210180624	0.953789663073109	0.999999999820103
GO:0140359	ABC-type transporter activity	1/1218	47/18639	0.0212765957446809	0.325594801383503	0.958427307067046	0.999999999820103
GO:0005249	voltage-gated potassium channel activity	3/1218	98/18639	0.0306122448979592	0.468457826480346	0.959035659428129	0.999999999820103
GO:0020037	heme binding	5/1218	142/18639	0.0352112676056338	0.538836467078332	0.95925159505603	0.999999999820103
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/1218	48/18639	0.0208333333333333	0.31881157635468	0.961150819329973	0.999999999820103
GO:0038187	pattern recognition receptor activity	1/1218	48/18639	0.0208333333333333	0.31881157635468	0.961150819329973	0.999999999820103
GO:0015293	symporter activity	5/1218	146/18639	0.0342465753424658	0.524073824144679	0.965713248699533	0.999999999820103
GO:0048020	CCR chemokine receptor binding	1/1218	50/18639	0.02	0.306059113300493	0.966074647907607	0.999999999820103
GO:0005010	insulin-like growth factor receptor activity	1/1218	51/18639	0.0196078431372549	0.300057954216169	0.968297525891819	0.999999999820103
GO:0005272	sodium channel activity	1/1218	51/18639	0.0196078431372549	0.300057954216169	0.968297525891819	0.999999999820103
GO:0015370	solute:sodium symporter activity	2/1218	79/18639	0.0253164556962025	0.387416599114548	0.968920512466633	0.999999999820103
GO:0033293	monocarboxylic acid binding	2/1218	79/18639	0.0253164556962025	0.387416599114548	0.968920512466633	0.999999999820103
GO:0015101	organic cation transmembrane transporter activity	2/1218	81/18639	0.0246913580246914	0.377850757161102	0.972281198300364	0.999999999820103
GO:0004864	protein phosphatase inhibitor activity	1/1218	53/18639	0.0188679245283019	0.288735012547635	0.972316192073398	0.999999999820103
GO:0016860	intramolecular oxidoreductase activity	1/1218	53/18639	0.0188679245283019	0.288735012547635	0.972316192073398	0.999999999820103
GO:0030170	pyridoxal phosphate binding	1/1218	56/18639	0.0178571428571429	0.273267065446868	0.977410191787442	0.999999999820103
GO:0004601	peroxidase activity	1/1218	57/18639	0.0175438596491228	0.268472906403941	0.978890813129685	0.999999999820103
GO:0070279	vitamin B6 binding	1/1218	57/18639	0.0175438596491228	0.268472906403941	0.978890813129685	0.999999999820103
GO:0016209	antioxidant activity	2/1218	86/18639	0.0232558139534884	0.355882689884294	0.979218477138794	0.999999999820103
GO:0015297	antiporter activity	4/1218	135/18639	0.0296296296296296	0.453420908593322	0.979411718023239	0.999999999820103
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/1218	58/18639	0.0172413793103448	0.26384406319008	0.98027446341534	0.999999999820103
GO:0016651	oxidoreductase activity, acting on NAD(P)H	2/1218	88/18639	0.0227272727272727	0.347794446932378	0.981493741694263	0.999999999820103
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	1/1218	59/18639	0.0169491525423729	0.259372129915672	0.981567488740141	0.999999999820103
GO:0015079	potassium ion transmembrane transporter activity	5/1218	160/18639	0.03125	0.47821736453202	0.98159770559351	0.999999999820103
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/1218	60/18639	0.0166666666666667	0.255049261083744	0.982775820210243	0.999999999820103
GO:0015291	secondary active transmembrane transporter activity	11/1218	287/18639	0.0383275261324042	0.586524433154254	0.982831366611995	0.999999999820103
GO:0015179	L-amino acid transmembrane transporter activity	1/1218	62/18639	0.0161290322580645	0.246821865564913	0.984960211991573	0.999999999820103
GO:0031406	carboxylic acid binding	6/1218	187/18639	0.0320855614973262	0.491003925081004	0.985225694241199	0.999999999820103
GO:0005507	copper ion binding	1/1218	63/18639	0.0158730158730159	0.242904058174994	0.985946294878706	0.999999999820103
GO:1901682	sulfur compound transmembrane transporter activity	1/1218	63/18639	0.0158730158730159	0.242904058174994	0.985946294878706	0.999999999820103
GO:0043177	organic acid binding	6/1218	189/18639	0.0317460317460317	0.485808116349988	0.986461984006366	0.999999999820103
GO:0015108	chloride transmembrane transporter activity	3/1218	121/18639	0.0247933884297521	0.379412123926231	0.987567917083395	0.999999999820103
GO:0005267	potassium channel activity	3/1218	124/18639	0.0241935483870968	0.37023279834737	0.989408949789878	0.999999999820103
GO:0005244	voltage-gated monoatomic ion channel activity	5/1218	173/18639	0.0289017341040462	0.44228195563655	0.98990387017809	0.999999999820103
GO:0019842	vitamin binding	4/1218	150/18639	0.0266666666666667	0.40807881773399	0.990134723005401	0.999999999820103
GO:0022832	voltage-gated channel activity	5/1218	175/18639	0.0285714285714286	0.437227304714989	0.990810578435163	0.999999999820103
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/1218	70/18639	0.0142857142857143	0.218613652357495	0.991258443897547	0.999999999820103
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	20/1218	484/18639	0.0413223140495868	0.632353539877051	0.991581994163004	0.999999999820103
GO:0005179	hormone activity	3/1218	132/18639	0.0227272727272727	0.347794446932378	0.993123731053996	0.999999999820103
GO:0001216	DNA-binding transcription activator activity	20/1218	491/18639	0.0407331975560081	0.623338316294282	0.993219873430612	0.999999999820103
GO:0022804	active transmembrane transporter activity	18/1218	457/18639	0.0393873085339169	0.602742236259176	0.994178856710865	0.999999999820103
GO:1901681	sulfur compound binding	9/1218	275/18639	0.0327272727272727	0.500824003582624	0.994401391341909	0.999999999820103
GO:0099094	ligand-gated monoatomic cation channel activity	3/1218	136/18639	0.0220588235294118	0.33756519849319	0.994472208088203	0.999999999820103
GO:0008083	growth factor activity	4/1218	162/18639	0.0246913580246914	0.377850757161102	0.994621903079358	0.999999999820103
GO:0019199	transmembrane receptor protein kinase activity	1/1218	78/18639	0.0128205128205128	0.196191739295188	0.994920385963045	0.999999999820103
GO:0000049	tRNA binding	1/1218	80/18639	0.0125	0.191286945812808	0.995565192452146	0.999999999820103
GO:0046873	metal ion transmembrane transporter activity	17/1218	450/18639	0.0377777777777778	0.578111658456486	0.996198958222837	0.999999999820103
GO:0022843	voltage-gated monoatomic cation channel activity	3/1218	143/18639	0.020979020979021	0.32104102793758	0.99624026869149	0.999999999820103
GO:0005254	chloride channel activity	1/1218	83/18639	0.0120481927710843	0.184372959819574	0.996382333351706	0.999999999820103
GO:0008201	heparin binding	4/1218	172/18639	0.0232558139534884	0.355882689884294	0.996790847711153	0.999999999820103
GO:0003823	antigen binding	4/1218	174/18639	0.0229885057471264	0.35179208425344	0.997108829562436	0.999999999820103
GO:0001664	G protein-coupled receptor binding	9/1218	297/18639	0.0303030303030303	0.463725929243171	0.997770974214398	0.999999999820103
GO:0015078	proton transmembrane transporter activity	4/1218	185/18639	0.0216216216216216	0.330874717081614	0.998381024596408	0.999999999820103
GO:0030594	neurotransmitter receptor activity	1/1218	97/18639	0.0103092783505155	0.157762429536336	0.998602075431422	0.999999999820103
GO:0015081	sodium ion transmembrane transporter activity	3/1218	164/18639	0.0182926829268293	0.279932115823621	0.998844151540987	0.999999999820103
GO:0005539	glycosaminoglycan binding	6/1218	242/18639	0.0247933884297521	0.379412123926231	0.998849097245518	0.999999999820103
GO:0008514	organic anion transmembrane transporter activity	7/1218	269/18639	0.0260223048327138	0.398218177156775	0.999001188214747	0.999999999820103
GO:0015171	amino acid transmembrane transporter activity	1/1218	102/18639	0.00980392156862745	0.150028977108085	0.999004765874581	0.999999999820103
GO:0005506	iron ion binding	2/1218	154/18639	0.012987012987013	0.198739683961359	0.999657197625777	0.999999999820103
GO:0015276	ligand-gated monoatomic ion channel activity	3/1218	186/18639	0.0161290322580645	0.246821865564913	0.999674388284844	0.999999999820103
GO:0022834	ligand-gated channel activity	3/1218	188/18639	0.0159574468085106	0.244196101037627	0.999710204494926	0.999999999820103
GO:0005216	monoatomic ion channel activity	13/1218	448/18639	0.0290178571428571	0.444058981351161	0.999841299116587	0.999999999820103
GO:0005125	cytokine activity	4/1218	234/18639	0.0170940170940171	0.261588985726917	0.99988961855905	0.999999999820103
GO:0005261	monoatomic cation channel activity	8/1218	341/18639	0.0234604105571848	0.359013622639874	0.999899514076299	0.999999999820103
GO:0003735	structural constituent of ribosome	2/1218	175/18639	0.0114285714285714	0.174890921885996	0.999907820961959	0.999999999820103
GO:0022836	gated channel activity	7/1218	318/18639	0.0220125786163522	0.336857514638907	0.999909180284717	0.999999999820103
GO:0046943	carboxylic acid transmembrane transporter activity	2/1218	188/18639	0.0106382978723404	0.162797400691751	0.999959413026614	0.999999999820103
GO:0005342	organic acid transmembrane transporter activity	2/1218	189/18639	0.0105820105820106	0.161936038783329	0.999961902701706	0.999999999820103
GO:0045182	translation regulator activity	3/1218	356/18639	0.00842696629213483	0.128957491559196	0.99999999025404	0.999999999820103
GO:0030371	translation repressor activity	1/1218	329/18639	0.00303951367781155	0.0465135430547861	0.999999999820103	0.999999999820103