ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0106310 protein serine kinase activity 51/1035 361/18639 0.141274238227147 2.5441647597254 7.57050499915754e-10 3.57781362393052e-07 GO:0030695 GTPase regulator activity 62/1035 489/18639 0.12678936605317 2.2833111051836 9.78445797715579e-10 3.57781362393052e-07 GO:0060589 nucleoside-triphosphatase regulator activity 62/1035 490/18639 0.126530612244898 2.2786512866016 1.0616657637776e-09 3.57781362393052e-07 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 37/1035 243/18639 0.152263374485597 2.74206477008409 2.24594586859181e-08 1.28724551403988e-06 GO:0141003 histone H2AX kinase activity 47/1035 354/18639 0.132768361581921 2.39098501596659 2.57324905255847e-08 1.28724551403988e-06 GO:0004676 3-phosphoinositide-dependent protein kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0004711 ribosomal protein S6 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0035175 histone H3S10 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0035979 histone H2AXS139 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0044022 histone H3S28 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0044023 histone H4S1 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0044024 histone H2AS1 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0044025 histone H2BS14 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0072354 histone H3T3 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0072371 histone H2AS121 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0072518 Rho-dependent protein serine/threonine kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0140823 histone H2BS36 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0140855 histone H3S57 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0140995 histone H2A kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0140997 histone H4 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0140998 histone H2B kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:1990244 histone H2AT120 kinase activity 37/1035 245/18639 0.151020408163265 2.71968056787933 2.80112772590281e-08 1.28724551403988e-06 GO:0004677 DNA-dependent protein kinase activity 37/1035 246/18639 0.150406504065041 2.70862495581478 3.12484331668466e-08 1.30436867628851e-06 GO:0140857 histone H3T45 kinase activity 37/1035 246/18639 0.150406504065041 2.70862495581478 3.12484331668466e-08 1.30436867628851e-06 GO:0140996 histone H3 kinase activity 47/1035 357/18639 0.131652661064426 2.37089270490805 3.34947913472333e-08 1.30436867628851e-06 GO:0035402 histone H3T11 kinase activity 37/1035 247/18639 0.149797570850202 2.69765886287625 3.48347717703163e-08 1.30436867628851e-06 GO:0035403 histone H3T6 kinase activity 37/1035 247/18639 0.149797570850202 2.69765886287625 3.48347717703163e-08 1.30436867628851e-06 GO:0004679 AMP-activated protein kinase activity 37/1035 248/18639 0.149193548387097 2.68678120617111 3.88051903677751e-08 1.40114455220788e-06 GO:0035173 histone kinase activity 47/1035 360/18639 0.130555555555556 2.35113526570048 4.3432849397421e-08 1.51415899106182e-06 GO:0031267 small GTPase binding 40/1035 283/18639 0.141342756183746 2.5453986787525 5.07926711036255e-08 1.71171301619218e-06 GO:0051020 GTPase binding 42/1035 315/18639 0.133333333333333 2.40115942028985 1.2571409484901e-07 4.09990160943062e-06 GO:0004674 protein serine/threonine kinase activity 52/1035 433/18639 0.120092378752887 2.16270709910634 1.32754932597968e-07 4.19422615176706e-06 GO:0005096 GTPase activator activity 36/1035 271/18639 0.132841328413284 2.39229905342532 1.07794219678068e-06 3.30242291195534e-05 GO:0005085 guanyl-nucleotide exchange factor activity 32/1035 230/18639 0.139130434782609 2.50555765595463 1.5408594196061e-06 4.58179080359343e-05 GO:0046975 histone H3K36 methyltransferase activity 7/1035 13/18639 0.538461538461538 9.69698996655518 2.03759135625769e-06 5.88572817479006e-05 GO:0003714 transcription corepressor activity 29/1035 204/18639 0.142156862745098 2.56005967604433 3.04679931270278e-06 8.55642806984031e-05 GO:0003712 transcription coregulator activity 50/1035 495/18639 0.101010101010101 1.81906016688625 3.21064127508013e-05 0.000877286034893516 GO:0140938 histone H3 methyltransferase activity 11/1035 47/18639 0.234042553191489 4.21480111008326 4.03239465030183e-05 0.00107282920827767 GO:0140297 DNA-binding transcription factor binding 49/1035 488/18639 0.100409836065574 1.80825017818959 4.47081351611838e-05 0.00115897242687069 GO:0003725 double-stranded RNA binding 14/1035 75/18639 0.186666666666667 3.3616231884058 5.67460578450676e-05 0.00143425661203408 GO:0000149 SNARE binding 17/1035 106/18639 0.160377358490566 2.88818703855619 7.20994240522857e-05 0.00177786628577709 GO:0019787 ubiquitin-like protein transferase activity 47/1035 479/18639 0.0981210855949896 1.76703276754107 0.000110721750838744 0.00266523071661833 GO:0016791 phosphatase activity 31/1035 273/18639 0.113553113553114 2.04494346233477 0.00012704379921982 0.00298700653514506 GO:0008276 protein methyltransferase activity 15/1035 95/18639 0.157894736842105 2.84347826086957 0.000225060344482556 0.00517127291526963 GO:0016755 aminoacyltransferase activity 47/1035 496/18639 0.094758064516129 1.70646914446003 0.000249098049075197 0.00559640283588942 GO:0042578 phosphoric ester hydrolase activity 37/1035 363/18639 0.101928374655647 1.83559707749431 0.000276095903736842 0.00606810779734667 GO:0042054 histone methyltransferase activity 12/1035 67/18639 0.17910447761194 3.22543802725503 0.000284370217941288 0.00611698490082217 GO:0008170 N-methyltransferase activity 15/1035 98/18639 0.153061224489796 2.7564330079858 0.000318999796937709 0.0067189332230005 GO:0016279 protein-lysine N-methyltransferase activity 12/1035 69/18639 0.173913043478261 3.13194706994329 0.000377447180367116 0.00778773672145212 GO:0016278 lysine N-methyltransferase activity 12/1035 70/18639 0.171428571428571 3.0872049689441 0.000432891731676839 0.00875307081450568 GO:0000287 magnesium ion binding 26/1035 230/18639 0.11304347826087 2.03576559546314 0.000461664316195434 0.00915181615046242 GO:0140939 histone H4 methyltransferase activity 6/1035 20/18639 0.3 5.40260869565217 0.000571102034382719 0.0111035414761717 GO:0019207 kinase regulator activity 30/1035 287/18639 0.104529616724739 1.88244205423421 0.000666876974476808 0.0126619325592447 GO:0004842 ubiquitin-protein transferase activity 42/1035 449/18639 0.0935412026726058 1.68455504986927 0.000676305003164404 0.0126619325592447 GO:0001784 phosphotyrosine residue binding 9/1035 47/18639 0.191489361702128 3.44847363552266 0.000977824337496342 0.0179741891856146 GO:0070566 adenylyltransferase activity 7/1035 30/18639 0.233333333333333 4.20202898550725 0.00105262548522504 0.0188665111290844 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 34/1035 349/18639 0.0974212034383954 1.75442880279058 0.00106369053843503 0.0188665111290844 GO:0035091 phosphatidylinositol binding 29/1035 284/18639 0.102112676056338 1.83891610532762 0.00117373952309661 0.0204594941008736 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 6/1035 23/18639 0.260869565217391 4.69792060491493 0.00128905549827761 0.0217205851459777 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 6/1035 23/18639 0.260869565217391 4.69792060491493 0.00128905549827761 0.0217205851459777 GO:0016779 nucleotidyltransferase activity 17/1035 136/18639 0.125 2.25108695652174 0.00143193900485947 0.0237326284248021 GO:0042169 SH2 domain binding 8/1035 41/18639 0.195121951219512 3.51389183457052 0.00163292981906536 0.0262998428174619 GO:0035035 histone acetyltransferase binding 6/1035 24/18639 0.25 4.50217391304348 0.00163886260880327 0.0262998428174619 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 5/1035 17/18639 0.294117647058824 5.29667519181586 0.00184636168229823 0.0291667447000549 GO:0019887 protein kinase regulator activity 26/1035 255/18639 0.101960784313725 1.83618073316283 0.00209688180462586 0.0326145769919499 GO:0052866 phosphatidylinositol phosphate phosphatase activity 7/1035 34/18639 0.205882352941176 3.7076726342711 0.00229172069587427 0.0351049942958923 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 5/1035 18/18639 0.277777777777778 5.0024154589372 0.00244073402070096 0.0368295835063981 GO:0052742 phosphatidylinositol kinase activity 6/1035 26/18639 0.230769230769231 4.15585284280936 0.00254924911691048 0.0379013361352426 GO:0043014 alpha-tubulin binding 8/1035 44/18639 0.181818181818182 3.27430830039526 0.00261466736868879 0.0383105610107879 GO:0005543 phospholipid binding 43/1035 497/18639 0.0865191146881288 1.55809640451404 0.0026859294020426 0.038792494649501 GO:0005154 epidermal growth factor receptor binding 7/1035 35/18639 0.2 3.60173913043478 0.00272955752264457 0.0388673613435727 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/1035 45/18639 0.177777777777778 3.20154589371981 0.00302811843929314 0.0423179078013403 GO:0061659 ubiquitin-like protein ligase activity 34/1035 372/18639 0.0913978494623656 1.64595605423095 0.00305559571661507 0.0423179078013403 GO:0005484 SNAP receptor activity 7/1035 36/18639 0.194444444444444 3.50169082125604 0.00322878220246133 0.0423399739632239 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 4/1035 12/18639 0.333333333333333 6.00289855072464 0.00326658552831995 0.0423399739632239 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 4/1035 12/18639 0.333333333333333 6.00289855072464 0.00326658552831995 0.0423399739632239 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 4/1035 12/18639 0.333333333333333 6.00289855072464 0.00326658552831995 0.0423399739632239 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 4/1035 12/18639 0.333333333333333 6.00289855072464 0.00326658552831995 0.0423399739632239 GO:0030276 clathrin binding 8/1035 46/18639 0.173913043478261 3.13194706994329 0.00349068881156773 0.0446719796012023 GO:0044389 ubiquitin-like protein ligase binding 30/1035 322/18639 0.093167701863354 1.67782878746962 0.00394176154528553 0.0498140115285459 GO:0032934 sterol binding 10/1035 68/18639 0.147058823529412 2.64833759590793 0.00412682361741408 0.0515088725580942 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 4/1035 13/18639 0.307692307692308 5.54113712374582 0.00451282493213128 0.0549694699564425 GO:0005035 death receptor activity 4/1035 13/18639 0.307692307692308 5.54113712374582 0.00451282493213128 0.0549694699564425 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 8/1035 48/18639 0.166666666666667 3.00144927536232 0.00457835675889811 0.0551037938481666 GO:0043178 alcohol binding 12/1035 92/18639 0.130434782608696 2.34896030245747 0.00483707365689242 0.0575327231425675 GO:0045309 protein phosphorylated amino acid binding 9/1035 59/18639 0.152542372881356 2.74708916728077 0.00497716832213251 0.0585106648101857 GO:0051219 phosphoprotein binding 12/1035 93/18639 0.129032258064516 2.32370266479663 0.00528057143943978 0.0613638818996967 GO:0042393 histone binding 24/1035 247/18639 0.097165991902834 1.74983277591973 0.00558754108400967 0.0641932276810657 GO:0008195 phosphatidate phosphatase activity 4/1035 14/18639 0.285714285714286 5.14534161490683 0.00604325857344335 0.0686487013230475 GO:0045296 cadherin binding 30/1035 334/18639 0.0898203592814371 1.61754751366832 0.00660782588503033 0.074227910775174 GO:0001727 lipid kinase activity 7/1035 41/18639 0.170731707317073 3.07465535524921 0.00683668169500922 0.0759547823478497 GO:0070577 lysine-acetylated histone binding 5/1035 23/18639 0.217391304347826 3.91493383742911 0.00761139449783649 0.0836426069273119 GO:0140030 modification-dependent protein binding 18/1035 173/18639 0.104046242774566 1.87373711987937 0.00773027183253796 0.0840355357279127 GO:0048487 beta-tubulin binding 7/1035 42/18639 0.166666666666667 3.00144927536232 0.00781990484223293 0.0841055722925265 GO:0061630 ubiquitin protein ligase activity 31/1035 353/18639 0.0878186968838527 1.58150018475182 0.00799855981925158 0.0851215155501405 GO:0004721 phosphoprotein phosphatase activity 18/1035 175/18639 0.102857142857143 1.85232298136646 0.00866980290657987 0.0913038618599193 GO:0140033 acetylation-dependent protein binding 5/1035 24/18639 0.208333333333333 3.7518115942029 0.00918311341600313 0.0957126563255584 GO:0004197 cysteine-type endopeptidase activity 11/1035 88/18639 0.125 2.25108695652174 0.00935343196744523 0.0962767947922365 GO:0015485 cholesterol binding 8/1035 54/18639 0.148148148148148 2.66795491143317 0.00942769800636144 0.0962767947922365 GO:0019902 phosphatase binding 19/1035 190/18639 0.1 1.80086956521739 0.00953472338545172 0.0963960534269169 GO:0016248 channel inhibitor activity 7/1035 44/18639 0.159090909090909 2.86501976284585 0.0100933859074904 0.10103379358884 GO:0019211 phosphatase activator activity 5/1035 25/18639 0.2 3.60173913043478 0.0109648170212222 0.108680686357408 GO:0017124 SH3 domain binding 13/1035 115/18639 0.11304347826087 2.03576559546314 0.0113738480728261 0.110771406292105 GO:0141110 transporter inhibitor activity 7/1035 45/18639 0.155555555555556 2.80135265700483 0.0113948825463688 0.110771406292105 GO:0030145 manganese ion binding 9/1035 68/18639 0.132352941176471 2.38350383631714 0.0125447396998651 0.118881882090405 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/1035 17/18639 0.235294117647059 4.23734015345269 0.0125819598255919 0.118881882090405 GO:0019198 transmembrane receptor protein phosphatase activity 4/1035 17/18639 0.235294117647059 4.23734015345269 0.0125819598255919 0.118881882090405 GO:0031072 heat shock protein binding 14/1035 131/18639 0.106870229007634 1.9245934284766 0.0140870896057679 0.131870811031772 GO:0003779 actin binding 36/1035 443/18639 0.0812641083521445 1.46346059475905 0.0144502586507704 0.134029463265403 GO:0015631 tubulin binding 32/1035 385/18639 0.0831168831168831 1.49682665160926 0.0151263511769854 0.139024918544839 GO:0005031 tumor necrosis factor receptor activity 3/1035 10/18639 0.3 5.40260869565217 0.0152661350535228 0.139045608460464 GO:0070063 RNA polymerase binding 8/1035 59/18639 0.135593220338983 2.4418570375829 0.015773413415778 0.142383222887067 GO:0036408 histone H3K14 acetyltransferase activity 5/1035 28/18639 0.178571428571429 3.21583850931677 0.0176861904637047 0.153737786070588 GO:0046875 ephrin receptor binding 5/1035 28/18639 0.178571428571429 3.21583850931677 0.0176861904637047 0.153737786070588 GO:0019209 kinase activator activity 15/1035 148/18639 0.101351351351351 1.82520564042303 0.0177035999964093 0.153737786070588 GO:0001222 transcription corepressor binding 7/1035 49/18639 0.142857142857143 2.57267080745342 0.0178261812842094 0.153737786070588 GO:0016763 pentosyltransferase activity 7/1035 49/18639 0.142857142857143 2.57267080745342 0.0178261812842094 0.153737786070588 GO:0031625 ubiquitin protein ligase binding 26/1035 302/18639 0.0860927152317881 1.55041750647855 0.0179436782950835 0.153737786070588 GO:0042577 lipid phosphatase activity 4/1035 19/18639 0.210526315789474 3.79130434782609 0.0187639319462008 0.156341444038425 GO:0042800 histone H3K4 methyltransferase activity 4/1035 19/18639 0.210526315789474 3.79130434782609 0.0187639319462008 0.156341444038425 GO:0050145 nucleoside monophosphate kinase activity 4/1035 19/18639 0.210526315789474 3.79130434782609 0.0187639319462008 0.156341444038425 GO:0140789 histone phosphatase activity 14/1035 136/18639 0.102941176470588 1.85383631713555 0.0190003332232263 0.156341444038425 GO:0019905 syntaxin binding 8/1035 61/18639 0.131147540983607 2.36179615110478 0.0190207691560102 0.156341444038425 GO:0016922 nuclear receptor binding 14/1035 137/18639 0.102189781021898 1.84030466518566 0.020121893016979 0.158805991385248 GO:0002162 dystroglycan binding 3/1035 11/18639 0.272727272727273 4.91146245059288 0.0201370080390712 0.158805991385248 GO:0032404 mismatch repair complex binding 3/1035 11/18639 0.272727272727273 4.91146245059288 0.0201370080390712 0.158805991385248 GO:0050998 nitric-oxide synthase binding 3/1035 11/18639 0.272727272727273 4.91146245059288 0.0201370080390712 0.158805991385248 GO:0140031 phosphorylation-dependent protein binding 3/1035 11/18639 0.272727272727273 4.91146245059288 0.0201370080390712 0.158805991385248 GO:0010484 histone H3 acetyltransferase activity 5/1035 29/18639 0.172413793103448 3.10494752623688 0.0204201571514167 0.158805991385248 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/1035 29/18639 0.172413793103448 3.10494752623688 0.0204201571514167 0.158805991385248 GO:0030331 nuclear estrogen receptor binding 6/1035 40/18639 0.15 2.70130434782609 0.0220067365249965 0.169838249059324 GO:0030295 protein kinase activator activity 14/1035 139/18639 0.100719424460432 1.81382546137003 0.0225138485313516 0.172435612615125 GO:0031624 ubiquitin conjugating enzyme binding 5/1035 30/18639 0.166666666666667 3.00144927536232 0.0234160322652895 0.174070651619174 GO:0043995 histone H4K5 acetyltransferase activity 5/1035 30/18639 0.166666666666667 3.00144927536232 0.0234160322652895 0.174070651619174 GO:0043996 histone H4K8 acetyltransferase activity 5/1035 30/18639 0.166666666666667 3.00144927536232 0.0234160322652895 0.174070651619174 GO:0043997 histone H4K12 acetyltransferase activity 5/1035 30/18639 0.166666666666667 3.00144927536232 0.0234160322652895 0.174070651619174 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 16/1035 167/18639 0.0958083832335329 1.72538401457954 0.0236324215587068 0.174263337917519 GO:0004713 protein tyrosine kinase activity 14/1035 140/18639 0.1 1.80086956521739 0.0237866870747949 0.174263337917519 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 6/1035 41/18639 0.146341463414634 2.63541887592789 0.0246073173529944 0.178978401754513 GO:0016273 arginine N-methyltransferase activity 3/1035 12/18639 0.25 4.50217391304348 0.0257604822093217 0.181316058033889 GO:0016274 protein-arginine N-methyltransferase activity 3/1035 12/18639 0.25 4.50217391304348 0.0257604822093217 0.181316058033889 GO:1990817 poly(A) RNA polymerase activity 3/1035 12/18639 0.25 4.50217391304348 0.0257604822093217 0.181316058033889 GO:0035401 histone H3Y41 kinase activity 12/1035 115/18639 0.104347826086957 1.87916824196597 0.0259653421768985 0.181316058033889 GO:0140801 histone H2AXY142 kinase activity 12/1035 115/18639 0.104347826086957 1.87916824196597 0.0259653421768985 0.181316058033889 GO:0005544 calcium-dependent phospholipid binding 7/1035 53/18639 0.132075471698113 2.37850697292863 0.0264599449526622 0.181316058033889 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/1035 21/18639 0.19047619047619 3.43022774327122 0.0265428057260292 0.181316058033889 GO:0051010 microtubule plus-end binding 4/1035 21/18639 0.19047619047619 3.43022774327122 0.0265428057260292 0.181316058033889 GO:0072542 protein phosphatase activator activity 4/1035 21/18639 0.19047619047619 3.43022774327122 0.0265428057260292 0.181316058033889 GO:0008235 metalloexopeptidase activity 8/1035 66/18639 0.121212121212121 2.1828722002635 0.0291726468123422 0.189137471968747 GO:0019208 phosphatase regulator activity 12/1035 117/18639 0.102564102564103 1.84704570791527 0.0292162374837128 0.189137471968747 GO:0140142 nucleocytoplasmic carrier activity 5/1035 32/18639 0.15625 2.81385869565217 0.0302231691400207 0.189137471968747 GO:0008200 ion channel inhibitor activity 6/1035 43/18639 0.13953488372093 2.51284125379171 0.030405483707603 0.189137471968747 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0032931 histone H3K56 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0043992 histone H3K9 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0043993 histone H3K18 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0043994 histone H3K23 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0043999 histone H2AK5 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0044012 histone H2AK9 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0044014 histone H2BK5 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0044015 histone H2BK12 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0044016 histone H3K4 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0044017 histone H3K27 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0044018 histone H3K36 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0046972 histone H4K16 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0140908 histone H3K122 acetyltransferase activity 4/1035 22/18639 0.181818181818182 3.27430830039526 0.0310552130037705 0.189137471968747 GO:0046974 histone H3K9 methyltransferase activity 3/1035 13/18639 0.230769230769231 4.15585284280936 0.0321347793924788 0.192238236484 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/1035 13/18639 0.230769230769231 4.15585284280936 0.0321347793924788 0.192238236484 GO:0140852 histone ubiquitin ligase activity 3/1035 13/18639 0.230769230769231 4.15585284280936 0.0321347793924788 0.192238236484 GO:0019205 nucleobase-containing compound kinase activity 6/1035 44/18639 0.136363636363636 2.45573122529644 0.0336126570444629 0.199896448658541 GO:0030296 protein tyrosine kinase activator activity 5/1035 33/18639 0.151515151515152 2.72859025032938 0.0340467543839611 0.201293968901664 GO:0042171 lysophosphatidic acid acyltransferase activity 4/1035 23/18639 0.173913043478261 3.13194706994329 0.0359907537418619 0.209118689844956 GO:0044013 histone H2B acetyltransferase activity 4/1035 23/18639 0.173913043478261 3.13194706994329 0.0359907537418619 0.209118689844956 GO:0071617 lysophospholipid acyltransferase activity 4/1035 23/18639 0.173913043478261 3.13194706994329 0.0359907537418619 0.209118689844956 GO:0004540 RNA nuclease activity 12/1035 121/18639 0.0991735537190083 1.78598634567014 0.0365822587584772 0.211340934884688 GO:0005496 steroid binding 11/1035 108/18639 0.101851851851852 1.83421900161031 0.03741874558283 0.214945180592279 GO:0044548 S100 protein binding 3/1035 14/18639 0.214285714285714 3.85900621118012 0.0392506487067612 0.222934864283908 GO:0061665 SUMO ligase activity 3/1035 14/18639 0.214285714285714 3.85900621118012 0.0392506487067612 0.222934864283908 GO:0043998 histone H2A acetyltransferase activity 4/1035 24/18639 0.166666666666667 3.00144927536232 0.0413522818070336 0.233559535792799 GO:0010485 histone H4 acetyltransferase activity 5/1035 35/18639 0.142857142857143 2.57267080745342 0.0425571143573021 0.23902912564018 GO:0051015 actin filament binding 18/1035 209/18639 0.0861244019138756 1.55098814229249 0.0432602092715474 0.241635754549914 GO:0061733 protein-lysine-acetyltransferase activity 6/1035 47/18639 0.127659574468085 2.29898242368178 0.0445133749975924 0.247269352321791 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/1035 15/18639 0.2 3.60173913043478 0.0470924958828076 0.254094864563257 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/1035 15/18639 0.2 3.60173913043478 0.0470924958828076 0.254094864563257 GO:0017081 chloride channel regulator activity 3/1035 15/18639 0.2 3.60173913043478 0.0470924958828076 0.254094864563257 GO:0042974 nuclear retinoic acid receptor binding 4/1035 25/18639 0.16 2.88139130434783 0.0471403703376644 0.254094864563257 GO:0000993 RNA polymerase II complex binding 5/1035 36/18639 0.138888888888889 2.5012077294686 0.0472500836180933 0.254094864563257 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1035 36/18639 0.138888888888889 2.5012077294686 0.0472500836180933 0.254094864563257 GO:0050660 flavin adenine dinucleotide binding 9/1035 86/18639 0.104651162790698 1.88463094034378 0.0488503033651883 0.261310352921722 GO:0004386 helicase activity 14/1035 155/18639 0.0903225806451613 1.62659186535764 0.0498488189896832 0.265248189466156 GO:0023023 MHC protein complex binding 5/1035 37/18639 0.135135135135135 2.43360752056404 0.0522373567687878 0.27650244865573 GO:1901981 phosphatidylinositol phosphate binding 16/1035 185/18639 0.0864864864864865 1.55750881316099 0.0526953400425071 0.277473899911327 GO:0043548 phosphatidylinositol 3-kinase binding 4/1035 26/18639 0.153846153846154 2.77056856187291 0.0533534333690386 0.279483529202581 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/1035 16/18639 0.1875 3.37663043478261 0.0556393941481358 0.286997078998803 GO:0004708 MAP kinase kinase activity 3/1035 16/18639 0.1875 3.37663043478261 0.0556393941481358 0.286997078998803 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 3/1035 16/18639 0.1875 3.37663043478261 0.0556393941481358 0.286997078998803 GO:0008238 exopeptidase activity 10/1035 102/18639 0.0980392156862745 1.76555839727195 0.0567932865651058 0.291461993488944 GO:0019903 protein phosphatase binding 13/1035 144/18639 0.0902777777777778 1.62578502415459 0.0574466068463865 0.292222326791644 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 5/1035 38/18639 0.131578947368421 2.3695652173913 0.0575195282211049 0.292222326791644 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/1035 89/18639 0.101123595505618 1.82110405471422 0.0584547342270986 0.294018588575108 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/1035 89/18639 0.101123595505618 1.82110405471422 0.0584547342270986 0.294018588575108 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/1035 27/18639 0.148148148148148 2.66795491143317 0.0599878565507284 0.300236252340527 GO:0140793 histone H2AXY142 phosphatase activity 9/1035 90/18639 0.1 1.80086956521739 0.0619075626324937 0.306831183997532 GO:0030544 Hsp70 protein binding 6/1035 51/18639 0.117647058823529 2.11867007672634 0.062128585802986 0.306831183997532 GO:0008168 methyltransferase activity 17/1035 204/18639 0.0833333333333333 1.50072463768116 0.0622160165375806 0.306831183997532 GO:0004659 prenyltransferase activity 3/1035 17/18639 0.176470588235294 3.17800511508951 0.0648659872172523 0.318347150857486 GO:0019789 SUMO transferase activity 4/1035 28/18639 0.142857142857143 2.57267080745342 0.067038134231899 0.322740731944999 GO:0045499 chemorepellent activity 4/1035 28/18639 0.142857142857143 2.57267080745342 0.067038134231899 0.322740731944999 GO:0046966 nuclear thyroid hormone receptor binding 4/1035 28/18639 0.142857142857143 2.57267080745342 0.067038134231899 0.322740731944999 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/1035 28/18639 0.142857142857143 2.57267080745342 0.067038134231899 0.322740731944999 GO:0004532 RNA exonuclease activity 5/1035 40/18639 0.125 2.25108695652174 0.0689661567385223 0.32889049274833 GO:0071949 FAD binding 5/1035 40/18639 0.125 2.25108695652174 0.0689661567385223 0.32889049274833 GO:0034212 protein N-acetyltransferase activity 6/1035 53/18639 0.113207547169811 2.03872026251025 0.0722786367668098 0.34306902240021 GO:0035615 clathrin adaptor activity 3/1035 18/18639 0.166666666666667 3.00144927536232 0.0747432940781621 0.353109674359915 GO:0048306 calcium-dependent protein binding 8/1035 80/18639 0.1 1.80086956521739 0.0756447963268528 0.355706460867201 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 6/1035 54/18639 0.111111111111111 2.00096618357488 0.0776888835397909 0.363627135457077 GO:0003713 transcription coactivator activity 20/1035 256/18639 0.078125 1.40692934782609 0.0782278871477013 0.364462644729613 GO:0004402 histone acetyltransferase activity 5/1035 42/18639 0.119047619047619 2.14389233954451 0.0815760103308895 0.374878847475133 GO:0019894 kinesin binding 5/1035 42/18639 0.119047619047619 2.14389233954451 0.0815760103308895 0.374878847475133 GO:0043175 RNA polymerase core enzyme binding 5/1035 42/18639 0.119047619047619 2.14389233954451 0.0815760103308895 0.374878847475133 GO:0003756 protein disulfide isomerase activity 3/1035 19/18639 0.157894736842105 2.84347826086957 0.0852394244779048 0.386444206937945 GO:0005520 insulin-like growth factor binding 3/1035 19/18639 0.157894736842105 2.84347826086957 0.0852394244779048 0.386444206937945 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/1035 19/18639 0.157894736842105 2.84347826086957 0.0852394244779048 0.386444206937945 GO:0048156 tau protein binding 5/1035 43/18639 0.116279069767442 2.09403437815976 0.0883089743602694 0.398573094099251 GO:0008017 microtubule binding 21/1035 276/18639 0.0760869565217391 1.37022684310019 0.0895658158779496 0.402449066011587 GO:0016741 transferase activity, transferring one-carbon groups 17/1035 215/18639 0.0790697674418605 1.42394337714863 0.0905917216038945 0.40525765726344 GO:0004725 protein tyrosine phosphatase activity 9/1035 98/18639 0.0918367346938776 1.65385980479148 0.0941494856027477 0.410397869792939 GO:0004860 protein kinase inhibitor activity 8/1035 84/18639 0.0952380952380952 1.71511387163561 0.0942416137875949 0.410397869792939 GO:0051117 ATPase binding 8/1035 84/18639 0.0952380952380952 1.71511387163561 0.0942416137875949 0.410397869792939 GO:0016004 phospholipase activator activity 3/1035 20/18639 0.15 2.70130434782609 0.096320213281667 0.410397869792939 GO:0061608 nuclear import signal receptor activity 3/1035 20/18639 0.15 2.70130434782609 0.096320213281667 0.410397869792939 GO:0022884 macromolecule transmembrane transporter activity 4/1035 32/18639 0.125 2.25108695652174 0.0992294258170317 0.410397869792939 GO:0051059 NF-kappaB binding 4/1035 32/18639 0.125 2.25108695652174 0.0992294258170317 0.410397869792939 GO:0120015 sterol transfer activity 4/1035 32/18639 0.125 2.25108695652174 0.0992294258170317 0.410397869792939 GO:0051539 4 iron, 4 sulfur cluster binding 5/1035 45/18639 0.111111111111111 2.00096618357488 0.1026076410511 0.410397869792939 GO:0140303 intramembrane lipid transporter activity 5/1035 45/18639 0.111111111111111 2.00096618357488 0.1026076410511 0.410397869792939 GO:0005131 growth hormone receptor binding 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0008140 cAMP response element binding protein binding 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0015279 store-operated calcium channel activity 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0016783 sulfurtransferase activity 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0030957 Tat protein binding 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0051880 G-quadruplex DNA binding 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0070513 death domain binding 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0140940 histone H2A methyltransferase activity 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0140999 histone H3K4 trimethyltransferase activity 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:1905394 retromer complex binding 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:1990259 histone H2AQ104 methyltransferase activity 2/1035 10/18639 0.2 3.60173913043478 0.103106883212074 0.410397869792939 GO:0005518 collagen binding 7/1035 72/18639 0.0972222222222222 1.75084541062802 0.104057790306127 0.41255853333135 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/1035 21/18639 0.142857142857143 2.57267080745342 0.107949781207607 0.424071940497847 GO:0140312 cargo adaptor activity 3/1035 21/18639 0.142857142857143 2.57267080745342 0.107949781207607 0.424071940497847 GO:0019239 deaminase activity 4/1035 33/18639 0.121212121212121 2.1828722002635 0.108220139118145 0.424071940497847 GO:0004180 carboxypeptidase activity 5/1035 46/18639 0.108695652173913 1.95746691871456 0.110161822273207 0.4283600089162 GO:0030291 protein serine/threonine kinase inhibitor activity 5/1035 46/18639 0.108695652173913 1.95746691871456 0.110161822273207 0.4283600089162 GO:0005178 integrin binding 13/1035 161/18639 0.0807453416149068 1.45411828247367 0.112699011105396 0.43654674416688 GO:0001098 basal transcription machinery binding 6/1035 60/18639 0.1 1.80086956521739 0.11473284239287 0.440793533188072 GO:0001099 basal RNA polymerase II transcription machinery binding 6/1035 60/18639 0.1 1.80086956521739 0.11473284239287 0.440793533188072 GO:0008376 acetylgalactosaminyltransferase activity 4/1035 34/18639 0.117647058823529 2.11867007672634 0.11756190870289 0.440793533188072 GO:0050321 tau-protein kinase activity 3/1035 22/18639 0.136363636363636 2.45573122529644 0.120091028818739 0.440793533188072 GO:0061133 endopeptidase activator activity 3/1035 22/18639 0.136363636363636 2.45573122529644 0.120091028818739 0.440793533188072 GO:0070034 telomerase RNA binding 3/1035 22/18639 0.136363636363636 2.45573122529644 0.120091028818739 0.440793533188072 GO:0004518 nuclease activity 16/1035 209/18639 0.076555023923445 1.37865612648221 0.120870207423902 0.440793533188072 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0001851 complement component C3b binding 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0004016 adenylate cyclase activity 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0008432 JUN kinase binding 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0015173 aromatic amino acid transmembrane transporter activity 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0019206 nucleoside kinase activity 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0032050 clathrin heavy chain binding 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0032794 GTPase activating protein binding 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1035 11/18639 0.181818181818182 3.27430830039526 0.121544633250519 0.440793533188072 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 6/1035 61/18639 0.0983606557377049 1.77134711332858 0.121643319247747 0.440793533188072 GO:0008094 ATP-dependent activity, acting on DNA 16/1035 210/18639 0.0761904761904762 1.37209109730849 0.124503286802094 0.449545796274702 GO:0019210 kinase inhibitor activity 8/1035 90/18639 0.0888888888888889 1.6007729468599 0.126568451478723 0.454556841330313 GO:0000175 3'-5'-RNA exonuclease activity 4/1035 35/18639 0.114285714285714 2.05813664596273 0.127239946682966 0.454556841330313 GO:0061631 ubiquitin conjugating enzyme activity 4/1035 35/18639 0.114285714285714 2.05813664596273 0.127239946682966 0.454556841330313 GO:0140034 methylation-dependent protein binding 7/1035 76/18639 0.0921052631578947 1.65869565217391 0.128485264091866 0.457389443650973 GO:0140103 catalytic activity, acting on a glycoprotein 3/1035 23/18639 0.130434782608696 2.34896030245747 0.13270607008027 0.470757322284748 GO:0002020 protease binding 11/1035 136/18639 0.0808823529411765 1.45658567774936 0.135295445413042 0.477346240123504 GO:0019888 protein phosphatase regulator activity 9/1035 107/18639 0.0841121495327103 1.51475010158472 0.140151801216476 0.477346240123504 GO:0005049 nuclear export signal receptor activity 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0005095 GTPase inhibitor activity 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0017166 vinculin binding 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0036009 protein-glutamine N-methyltransferase activity 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0045295 gamma-catenin binding 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0097677 STAT family protein binding 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1035 12/18639 0.166666666666667 3.00144927536232 0.140701463458758 0.477346240123504 GO:0061775 cohesin loader activity 12/1035 153/18639 0.0784313725490196 1.41244671781756 0.143936035043482 0.484736624954095 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/1035 24/18639 0.125 2.25108695652174 0.145756611262161 0.484736624954095 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/1035 24/18639 0.125 2.25108695652174 0.145756611262161 0.484736624954095 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/1035 24/18639 0.125 2.25108695652174 0.145756611262161 0.484736624954095 GO:0060229 lipase activator activity 3/1035 24/18639 0.125 2.25108695652174 0.145756611262161 0.484736624954095 GO:0070300 phosphatidic acid binding 3/1035 24/18639 0.125 2.25108695652174 0.145756611262161 0.484736624954095 GO:0046332 SMAD binding 7/1035 79/18639 0.0886075949367089 1.5957072096863 0.148522632211791 0.492316003823346 GO:0070851 growth factor receptor binding 11/1035 139/18639 0.079136690647482 1.42514857679074 0.150323865261955 0.495040481367546 GO:0140767 enzyme-substrate adaptor activity 11/1035 139/18639 0.079136690647482 1.42514857679074 0.150323865261955 0.495040481367546 GO:0005048 signal sequence binding 5/1035 51/18639 0.0980392156862745 1.76555839727195 0.151694399085205 0.497931939854359 GO:0140104 molecular carrier activity 18/1035 249/18639 0.072289156626506 1.30183342063908 0.152912284225104 0.50030524062 GO:0008234 cysteine-type peptidase activity 14/1035 187/18639 0.0748663101604278 1.3482445942804 0.157887947327672 0.512339913689066 GO:0042162 telomeric DNA binding 4/1035 38/18639 0.105263157894737 1.89565217391304 0.158132733971355 0.512339913689066 GO:0004709 MAP kinase kinase kinase activity 3/1035 25/18639 0.12 2.16104347826087 0.159204280479138 0.512339913689066 GO:0008139 nuclear localization sequence binding 3/1035 25/18639 0.12 2.16104347826087 0.159204280479138 0.512339913689066 GO:0120020 cholesterol transfer activity 3/1035 25/18639 0.12 2.16104347826087 0.159204280479138 0.512339913689066 GO:0031994 insulin-like growth factor I binding 2/1035 13/18639 0.153846153846154 2.77056856187291 0.160440860561718 0.512339913689066 GO:0043560 insulin receptor substrate binding 2/1035 13/18639 0.153846153846154 2.77056856187291 0.160440860561718 0.512339913689066 GO:0016757 glycosyltransferase activity 19/1035 267/18639 0.0711610486891386 1.28151766813223 0.160644661364425 0.512339913689066 GO:0001618 virus receptor activity 7/1035 81/18639 0.0864197530864197 1.55630703166935 0.162647348216608 0.515474824598716 GO:0015101 organic cation transmembrane transporter activity 7/1035 81/18639 0.0864197530864197 1.55630703166935 0.162647348216608 0.515474824598716 GO:0016407 acetyltransferase activity 8/1035 96/18639 0.0833333333333333 1.50072463768116 0.16390391109019 0.517833919100569 GO:0042826 histone deacetylase binding 10/1035 127/18639 0.078740157480315 1.41800753166724 0.168316668647052 0.528956604761071 GO:0140658 ATP-dependent chromatin remodeler activity 12/1035 158/18639 0.0759493670886076 1.36774903687397 0.16876994353058 0.528956604761071 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/1035 39/18639 0.102564102564103 1.84704570791527 0.168994048801015 0.528956604761071 GO:0140272 exogenous protein binding 7/1035 82/18639 0.0853658536585366 1.5373276776246 0.169927753129591 0.530237525969186 GO:0004435 phosphatidylinositol phospholipase C activity 3/1035 26/18639 0.115384615384615 2.07792642140468 0.17301091271089 0.534905298931834 GO:0050681 nuclear androgen receptor binding 3/1035 26/18639 0.115384615384615 2.07792642140468 0.17301091271089 0.534905298931834 GO:0070006 metalloaminopeptidase activity 3/1035 26/18639 0.115384615384615 2.07792642140468 0.17301091271089 0.534905298931834 GO:0005516 calmodulin binding 15/1035 207/18639 0.072463768115942 1.3049779458097 0.177151952121858 0.543329091562607 GO:0001540 amyloid-beta binding 7/1035 83/18639 0.0843373493975904 1.51880565741226 0.177347774694026 0.543329091562607 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/1035 83/18639 0.0843373493975904 1.51880565741226 0.177347774694026 0.543329091562607 GO:0005545 1-phosphatidylinositol binding 2/1035 14/18639 0.142857142857143 2.57267080745342 0.18063922920421 0.545153017090915 GO:0030983 mismatched DNA binding 2/1035 14/18639 0.142857142857143 2.57267080745342 0.18063922920421 0.545153017090915 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/1035 14/18639 0.142857142857143 2.57267080745342 0.18063922920421 0.545153017090915 GO:0042043 neurexin family protein binding 2/1035 14/18639 0.142857142857143 2.57267080745342 0.18063922920421 0.545153017090915 GO:0070742 C2H2 zinc finger domain binding 2/1035 14/18639 0.142857142857143 2.57267080745342 0.18063922920421 0.545153017090915 GO:0140098 catalytic activity, acting on RNA 26/1035 387/18639 0.0671834625322997 1.20988652960342 0.182316622950307 0.548577695841548 GO:0008080 N-acetyltransferase activity 6/1035 69/18639 0.0869565217391304 1.56597353497164 0.183690150804179 0.551070452412537 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/1035 27/18639 0.111111111111111 2.00096618357488 0.18713879473091 0.555457478327073 GO:0023026 MHC class II protein complex binding 3/1035 27/18639 0.111111111111111 2.00096618357488 0.18713879473091 0.555457478327073 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1035 27/18639 0.111111111111111 2.00096618357488 0.18713879473091 0.555457478327073 GO:0004175 endopeptidase activity 27/1035 405/18639 0.0666666666666667 1.20057971014493 0.187350148476293 0.555457478327073 GO:0008374 O-acyltransferase activity 5/1035 55/18639 0.0909090909090909 1.63715415019763 0.188913818591834 0.558455761977615 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1035 41/18639 0.0975609756097561 1.75694591728526 0.191457572800667 0.561053930728911 GO:0017080 sodium channel regulator activity 4/1035 41/18639 0.0975609756097561 1.75694591728526 0.191457572800667 0.561053930728911 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/1035 41/18639 0.0975609756097561 1.75694591728526 0.191457572800667 0.561053930728911 GO:0000774 adenyl-nucleotide exchange factor activity 2/1035 15/18639 0.133333333333333 2.40115942028985 0.201184880484426 0.577834983436804 GO:0005041 low-density lipoprotein particle receptor activity 2/1035 15/18639 0.133333333333333 2.40115942028985 0.201184880484426 0.577834983436804 GO:0033130 acetylcholine receptor binding 2/1035 15/18639 0.133333333333333 2.40115942028985 0.201184880484426 0.577834983436804 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/1035 15/18639 0.133333333333333 2.40115942028985 0.201184880484426 0.577834983436804 GO:0140776 protein-containing complex destabilizing activity 2/1035 15/18639 0.133333333333333 2.40115942028985 0.201184880484426 0.577834983436804 GO:0141050 histone H3K deacetylase activity 2/1035 15/18639 0.133333333333333 2.40115942028985 0.201184880484426 0.577834983436804 GO:0141051 histone H4K deacetylase activity 2/1035 15/18639 0.133333333333333 2.40115942028985 0.201184880484426 0.577834983436804 GO:0051879 Hsp90 protein binding 4/1035 42/18639 0.0952380952380952 1.71511387163561 0.203024053060643 0.581465489077367 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 16/1035 229/18639 0.0698689956331878 1.25824947788115 0.205022549903975 0.58553050269186 GO:0004722 protein serine/threonine phosphatase activity 8/1035 103/18639 0.0776699029126214 1.39873364288729 0.213027193505188 0.598958624433865 GO:0033218 amide binding 17/1035 247/18639 0.0688259109311741 1.23946488294314 0.213188482852109 0.598958624433865 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/1035 43/18639 0.0930232558139535 1.67522750252781 0.214789702158118 0.598958624433865 GO:0003785 actin monomer binding 3/1035 29/18639 0.103448275862069 1.86296851574213 0.216210935155332 0.598958624433865 GO:0004629 phospholipase C activity 3/1035 29/18639 0.103448275862069 1.86296851574213 0.216210935155332 0.598958624433865 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/1035 29/18639 0.103448275862069 1.86296851574213 0.216210935155332 0.598958624433865 GO:0097472 cyclin-dependent protein kinase activity 3/1035 29/18639 0.103448275862069 1.86296851574213 0.216210935155332 0.598958624433865 GO:0000510 H3-H4 histone complex chaperone activity 11/1035 151/18639 0.0728476821192053 1.31189173625108 0.218236987544053 0.598958624433865 GO:0140584 chromatin extrusion motor activity 11/1035 151/18639 0.0728476821192053 1.31189173625108 0.218236987544053 0.598958624433865 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 11/1035 151/18639 0.0728476821192053 1.31189173625108 0.218236987544053 0.598958624433865 GO:0140849 ATP-dependent H2AZ histone chaperone activity 11/1035 151/18639 0.0728476821192053 1.31189173625108 0.218236987544053 0.598958624433865 GO:0004521 RNA endonuclease activity 6/1035 73/18639 0.0821917808219178 1.4801667659321 0.218598991921135 0.598958624433865 GO:0043539 protein serine/threonine kinase activator activity 6/1035 73/18639 0.0821917808219178 1.4801667659321 0.218598991921135 0.598958624433865 GO:0008408 3'-5' exonuclease activity 5/1035 58/18639 0.0862068965517241 1.55247376311844 0.21874397634836 0.598958624433865 GO:0000062 fatty-acyl-CoA binding 2/1035 16/18639 0.125 2.25108695652174 0.221977092818182 0.598958624433865 GO:0005159 insulin-like growth factor receptor binding 2/1035 16/18639 0.125 2.25108695652174 0.221977092818182 0.598958624433865 GO:0008142 oxysterol binding 2/1035 16/18639 0.125 2.25108695652174 0.221977092818182 0.598958624433865 GO:0015923 mannosidase activity 2/1035 16/18639 0.125 2.25108695652174 0.221977092818182 0.598958624433865 GO:0022858 alanine transmembrane transporter activity 2/1035 16/18639 0.125 2.25108695652174 0.221977092818182 0.598958624433865 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1035 16/18639 0.125 2.25108695652174 0.221977092818182 0.598958624433865 GO:0042277 peptide binding 17/1035 249/18639 0.0682730923694779 1.22950934171468 0.222667033222997 0.598958624433865 GO:0016247 channel regulator activity 12/1035 168/18639 0.0714285714285714 1.28633540372671 0.224150280202384 0.598958624433865 GO:0015616 DNA translocase activity 11/1035 152/18639 0.0723684210526316 1.30326086956522 0.224401614908288 0.598958624433865 GO:0140674 ATP-dependent histone chaperone activity 11/1035 152/18639 0.0723684210526316 1.30326086956522 0.224401614908288 0.598958624433865 GO:0003727 single-stranded RNA binding 7/1035 89/18639 0.0786516853932584 1.41641426477772 0.224535428942072 0.598958624433865 GO:0035064 methylated histone binding 6/1035 74/18639 0.0810810810810811 1.46016451233843 0.227657614169729 0.60568907348841 GO:0016887 ATP hydrolysis activity 27/1035 417/18639 0.0647482014388489 1.16603065373788 0.230214086960285 0.61088304965052 GO:0098918 structural constituent of synapse 3/1035 30/18639 0.1 1.80086956521739 0.231083747660274 0.611585520640149 GO:0141108 transporter regulator activity 12/1035 170/18639 0.0705882352941176 1.27120204603581 0.236037970651253 0.61553237562453 GO:0019003 GDP binding 6/1035 75/18639 0.08 1.44069565217391 0.236834183748295 0.61553237562453 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 9/1035 122/18639 0.0737704918032787 1.32851033499644 0.236985308507796 0.61553237562453 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1035 60/18639 0.0833333333333333 1.50072463768116 0.239383084613012 0.61553237562453 GO:0004550 nucleoside diphosphate kinase activity 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0005092 GDP-dissociation inhibitor activity 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0008429 phosphatidylethanolamine binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0016018 cyclosporin A binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0016805 dipeptidase activity 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0030169 low-density lipoprotein particle binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0032183 SUMO binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0038191 neuropilin binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0046965 nuclear retinoid X receptor binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0051787 misfolded protein binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:1901567 fatty acid derivative binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:1990226 histone methyltransferase binding 2/1035 17/18639 0.117647058823529 2.11867007672634 0.242925240231639 0.61553237562453 GO:0098631 cell adhesion mediator activity 6/1035 76/18639 0.0789473684210526 1.42173913043478 0.24612123400456 0.617901480444452 GO:0016411 acylglycerol O-acyltransferase activity 3/1035 31/18639 0.0967741935483871 1.74277699859748 0.246135187366831 0.617901480444452 GO:0070325 lipoprotein particle receptor binding 3/1035 31/18639 0.0967741935483871 1.74277699859748 0.246135187366831 0.617901480444452 GO:0140597 protein carrier chaperone 13/1035 188/18639 0.0691489361702128 1.24528214616096 0.246304942254317 0.617901480444452 GO:0003724 RNA helicase activity 6/1035 77/18639 0.0779220779220779 1.40327498588368 0.255511240156958 0.637831762465889 GO:0051540 metal cluster binding 6/1035 77/18639 0.0779220779220779 1.40327498588368 0.255511240156958 0.637831762465889 GO:0015179 L-amino acid transmembrane transporter activity 5/1035 62/18639 0.0806451612903226 1.4523141654979 0.260522028020528 0.638400505548644 GO:0071813 lipoprotein particle binding 3/1035 32/18639 0.09375 1.6883152173913 0.261332335113362 0.638400505548644 GO:0071814 protein-lipid complex binding 3/1035 32/18639 0.09375 1.6883152173913 0.261332335113362 0.638400505548644 GO:0005504 fatty acid binding 4/1035 47/18639 0.0851063829787234 1.53265494912118 0.263486122436107 0.638400505548644 GO:0061749 forked DNA-dependent helicase activity 4/1035 47/18639 0.0851063829787234 1.53265494912118 0.263486122436107 0.638400505548644 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/1035 47/18639 0.0851063829787234 1.53265494912118 0.263486122436107 0.638400505548644 GO:0000400 four-way junction DNA binding 2/1035 18/18639 0.111111111111111 2.00096618357488 0.263947983500824 0.638400505548644 GO:0004706 JUN kinase kinase kinase activity 2/1035 18/18639 0.111111111111111 2.00096618357488 0.263947983500824 0.638400505548644 GO:0017128 phospholipid scramblase activity 2/1035 18/18639 0.111111111111111 2.00096618357488 0.263947983500824 0.638400505548644 GO:0030228 lipoprotein particle receptor activity 2/1035 18/18639 0.111111111111111 2.00096618357488 0.263947983500824 0.638400505548644 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1035 18/18639 0.111111111111111 2.00096618357488 0.263947983500824 0.638400505548644 GO:0050811 GABA receptor binding 2/1035 18/18639 0.111111111111111 2.00096618357488 0.263947983500824 0.638400505548644 GO:0070064 proline-rich region binding 2/1035 18/18639 0.111111111111111 2.00096618357488 0.263947983500824 0.638400505548644 GO:0008186 ATP-dependent activity, acting on RNA 6/1035 79/18639 0.0759493670886076 1.36774903687397 0.274569844403054 0.655003826263994 GO:0009378 four-way junction helicase activity 4/1035 48/18639 0.0833333333333333 1.50072463768116 0.275980664095755 0.655003826263994 GO:0036121 double-stranded DNA helicase activity 4/1035 48/18639 0.0833333333333333 1.50072463768116 0.275980664095755 0.655003826263994 GO:0043138 3'-5' DNA helicase activity 4/1035 48/18639 0.0833333333333333 1.50072463768116 0.275980664095755 0.655003826263994 GO:0140693 molecular condensate scaffold activity 4/1035 48/18639 0.0833333333333333 1.50072463768116 0.275980664095755 0.655003826263994 GO:0003689 DNA clamp loader activity 11/1035 160/18639 0.06875 1.23809782608696 0.2760025735613 0.655003826263994 GO:0099106 ion channel regulator activity 11/1035 160/18639 0.06875 1.23809782608696 0.2760025735613 0.655003826263994 GO:0019956 chemokine binding 3/1035 33/18639 0.0909090909090909 1.63715415019763 0.276643554712884 0.655003826263994 GO:0140416 transcription regulator inhibitor activity 3/1035 33/18639 0.0909090909090909 1.63715415019763 0.276643554712884 0.655003826263994 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 9/1035 128/18639 0.0703125 1.26623641304348 0.281151703006623 0.661877032261765 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1035 19/18639 0.105263157894737 1.89565217391304 0.284972519856461 0.661877032261765 GO:0008301 DNA binding, bending 2/1035 19/18639 0.105263157894737 1.89565217391304 0.284972519856461 0.661877032261765 GO:0043395 heparan sulfate proteoglycan binding 2/1035 19/18639 0.105263157894737 1.89565217391304 0.284972519856461 0.661877032261765 GO:0120227 acyl-CoA binding 2/1035 19/18639 0.105263157894737 1.89565217391304 0.284972519856461 0.661877032261765 GO:1990380 K48-linked deubiquitinase activity 2/1035 19/18639 0.105263157894737 1.89565217391304 0.284972519856461 0.661877032261765 GO:0035254 glutamate receptor binding 4/1035 49/18639 0.0816326530612245 1.47009760425909 0.288569072195355 0.661877032261765 GO:0060590 ATPase regulator activity 4/1035 49/18639 0.0816326530612245 1.47009760425909 0.288569072195355 0.661877032261765 GO:0035591 signaling adaptor activity 9/1035 129/18639 0.0697674418604651 1.25642062689585 0.288731784138201 0.661877032261765 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1035 34/18639 0.0882352941176471 1.58900255754476 0.292038552713851 0.661877032261765 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/1035 34/18639 0.0882352941176471 1.58900255754476 0.292038552713851 0.661877032261765 GO:0016831 carboxy-lyase activity 3/1035 34/18639 0.0882352941176471 1.58900255754476 0.292038552713851 0.661877032261765 GO:0004857 enzyme inhibitor activity 26/1035 416/18639 0.0625 1.12554347826087 0.293933621550849 0.661877032261765 GO:0030971 receptor tyrosine kinase binding 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0033192 calmodulin-dependent protein phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0140791 histone H2AXS140 phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:1990439 MAP kinase serine/threonine phosphatase activity 6/1035 81/18639 0.0740740740740741 1.33397745571659 0.2939493446939 0.661877032261765 GO:0042626 ATPase-coupled transmembrane transporter activity 7/1035 98/18639 0.0714285714285714 1.28633540372671 0.302014774164359 0.677884478428302 GO:0140713 histone chaperone activity 11/1035 164/18639 0.0670731707317073 1.20790031813362 0.303084389978549 0.677884478428302 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 6/1035 82/18639 0.0731707317073171 1.31770943796394 0.303740522975293 0.677884478428302 GO:0033549 MAP kinase phosphatase activity 6/1035 82/18639 0.0731707317073171 1.31770943796394 0.303740522975293 0.677884478428302 GO:0030742 GTP-dependent protein binding 2/1035 20/18639 0.1 1.80086956521739 0.30593388725366 0.679778373655935 GO:0140664 ATP-dependent DNA damage sensor activity 2/1035 20/18639 0.1 1.80086956521739 0.30593388725366 0.679778373655935 GO:0140566 histone reader activity 3/1035 35/18639 0.0857142857142857 1.54360248447205 0.307488422029246 0.680698338568684 GO:0001221 transcription coregulator binding 8/1035 115/18639 0.0695652173913043 1.25277882797732 0.30769450121255 0.680698338568684 GO:0016830 carbon-carbon lyase activity 4/1035 51/18639 0.0784313725490196 1.41244671781756 0.313961620498954 0.693046284551185 GO:0140097 catalytic activity, acting on DNA 21/1035 336/18639 0.0625 1.12554347826087 0.319059562704302 0.69993397665931 GO:0004190 aspartic-type endopeptidase activity 3/1035 36/18639 0.0833333333333333 1.50072463768116 0.32296567134408 0.69993397665931 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1035 36/18639 0.0833333333333333 1.50072463768116 0.32296567134408 0.69993397665931 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1035 36/18639 0.0833333333333333 1.50072463768116 0.32296567134408 0.69993397665931 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1035 36/18639 0.0833333333333333 1.50072463768116 0.32296567134408 0.69993397665931 GO:0004527 exonuclease activity 6/1035 84/18639 0.0714285714285714 1.28633540372671 0.323488264580626 0.69993397665931 GO:0017018 myosin phosphatase activity 6/1035 84/18639 0.0714285714285714 1.28633540372671 0.323488264580626 0.69993397665931 GO:0016874 ligase activity 11/1035 167/18639 0.0658682634730539 1.18620151002343 0.32382861796033 0.69993397665931 GO:1990782 protein tyrosine kinase binding 8/1035 117/18639 0.0683760683760684 1.23136380527685 0.324344754190697 0.69993397665931 GO:0061135 endopeptidase regulator activity 12/1035 184/18639 0.0652173913043478 1.17448015122873 0.325027849134608 0.69993397665931 GO:0001846 opsonin binding 2/1035 21/18639 0.0952380952380952 1.71511387163561 0.326774319469035 0.69993397665931 GO:0009975 cyclase activity 2/1035 21/18639 0.0952380952380952 1.71511387163561 0.326774319469035 0.69993397665931 GO:0015174 basic amino acid transmembrane transporter activity 2/1035 21/18639 0.0952380952380952 1.71511387163561 0.326774319469035 0.69993397665931 GO:0070182 DNA polymerase binding 2/1035 21/18639 0.0952380952380952 1.71511387163561 0.326774319469035 0.69993397665931 GO:0043394 proteoglycan binding 3/1035 37/18639 0.0810810810810811 1.46016451233843 0.338444242032543 0.721871579525107 GO:0070001 aspartic-type peptidase activity 3/1035 37/18639 0.0810810810810811 1.46016451233843 0.338444242032543 0.721871579525107 GO:0016860 intramolecular oxidoreductase activity 4/1035 53/18639 0.0754716981132075 1.3591468416735 0.339536244915246 0.722676091809081 GO:0004407 histone deacetylase activity 2/1035 22/18639 0.0909090909090909 1.63715415019763 0.347442648534065 0.730279662511308 GO:0008649 rRNA methyltransferase activity 2/1035 22/18639 0.0909090909090909 1.63715415019763 0.347442648534065 0.730279662511308 GO:0015377 chloride:monoatomic cation symporter activity 2/1035 22/18639 0.0909090909090909 1.63715415019763 0.347442648534065 0.730279662511308 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1035 22/18639 0.0909090909090909 1.63715415019763 0.347442648534065 0.730279662511308 GO:0033558 protein lysine deacetylase activity 2/1035 22/18639 0.0909090909090909 1.63715415019763 0.347442648534065 0.730279662511308 GO:0033691 sialic acid binding 2/1035 22/18639 0.0909090909090909 1.63715415019763 0.347442648534065 0.730279662511308 GO:0042887 amide transmembrane transporter activity 3/1035 38/18639 0.0789473684210526 1.42173913043478 0.353899514152073 0.740771032728253 GO:0043531 ADP binding 3/1035 38/18639 0.0789473684210526 1.42173913043478 0.353899514152073 0.740771032728253 GO:0003697 single-stranded DNA binding 8/1035 121/18639 0.0661157024793388 1.19065756378009 0.358077109162296 0.747966854055954 GO:0098632 cell-cell adhesion mediator activity 4/1035 55/18639 0.0727272727272727 1.3097233201581 0.36517282289035 0.757344207431182 GO:0140313 molecular sequestering activity 4/1035 55/18639 0.0727272727272727 1.3097233201581 0.36517282289035 0.757344207431182 GO:0004602 glutathione peroxidase activity 2/1035 23/18639 0.0869565217391304 1.56597353497164 0.36789375124395 0.757344207431182 GO:0005158 insulin receptor binding 2/1035 23/18639 0.0869565217391304 1.56597353497164 0.36789375124395 0.757344207431182 GO:0016849 phosphorus-oxygen lyase activity 2/1035 23/18639 0.0869565217391304 1.56597353497164 0.36789375124395 0.757344207431182 GO:0099186 structural constituent of postsynapse 2/1035 23/18639 0.0869565217391304 1.56597353497164 0.36789375124395 0.757344207431182 GO:0140102 catalytic activity, acting on a rRNA 2/1035 23/18639 0.0869565217391304 1.56597353497164 0.36789375124395 0.757344207431182 GO:0000217 DNA secondary structure binding 3/1035 39/18639 0.0769230769230769 1.38528428093645 0.369308302931328 0.757344207431182 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/1035 39/18639 0.0769230769230769 1.38528428093645 0.369308302931328 0.757344207431182 GO:0004177 aminopeptidase activity 3/1035 40/18639 0.075 1.35065217391304 0.384648847031421 0.783147714771467 GO:0061791 GTPase motor activity 3/1035 40/18639 0.075 1.35065217391304 0.384648847031421 0.783147714771467 GO:1990606 membrane scission GTPase motor activity 3/1035 40/18639 0.075 1.35065217391304 0.384648847031421 0.783147714771467 GO:0005315 phosphate transmembrane transporter activity 2/1035 24/18639 0.0833333333333333 1.50072463768116 0.38808803669684 0.783147714771467 GO:0015295 solute:proton symporter activity 2/1035 24/18639 0.0833333333333333 1.50072463768116 0.38808803669684 0.783147714771467 GO:0019957 C-C chemokine binding 2/1035 24/18639 0.0833333333333333 1.50072463768116 0.38808803669684 0.783147714771467 GO:0030215 semaphorin receptor binding 2/1035 24/18639 0.0833333333333333 1.50072463768116 0.38808803669684 0.783147714771467 GO:0140612 DNA damage sensor activity 2/1035 24/18639 0.0833333333333333 1.50072463768116 0.38808803669684 0.783147714771467 GO:0017116 single-stranded DNA helicase activity 4/1035 58/18639 0.0689655172413793 1.24197901049475 0.403501258703156 0.798689117548291 GO:0000030 mannosyltransferase activity 2/1035 25/18639 0.08 1.44069565217391 0.407990972020118 0.798689117548291 GO:0001848 complement binding 2/1035 25/18639 0.08 1.44069565217391 0.407990972020118 0.798689117548291 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1035 25/18639 0.08 1.44069565217391 0.407990972020118 0.798689117548291 GO:0015662 P-type ion transporter activity 2/1035 25/18639 0.08 1.44069565217391 0.407990972020118 0.798689117548291 GO:0017056 structural constituent of nuclear pore 2/1035 25/18639 0.08 1.44069565217391 0.407990972020118 0.798689117548291 GO:0140358 P-type transmembrane transporter activity 2/1035 25/18639 0.08 1.44069565217391 0.407990972020118 0.798689117548291 GO:0004519 endonuclease activity 8/1035 127/18639 0.062992125984252 1.13440602533379 0.409238559591306 0.798689117548291 GO:0019783 ubiquitin-like protein peptidase activity 8/1035 127/18639 0.062992125984252 1.13440602533379 0.409238559591306 0.798689117548291 GO:0008194 UDP-glycosyltransferase activity 9/1035 145/18639 0.0620689655172414 1.11778110944528 0.414832525902632 0.798689117548291 GO:0016859 cis-trans isomerase activity 3/1035 42/18639 0.0714285714285714 1.28633540372671 0.415045154093327 0.798689117548291 GO:0051536 iron-sulfur cluster binding 5/1035 76/18639 0.0657894736842105 1.18478260869565 0.415351024496767 0.798689117548291 GO:0001786 phosphatidylserine binding 4/1035 59/18639 0.0677966101694915 1.22092851879145 0.416192581923168 0.798689117548291 GO:0031593 polyubiquitin modification-dependent protein binding 4/1035 59/18639 0.0677966101694915 1.22092851879145 0.416192581923168 0.798689117548291 GO:0070888 E-box binding 4/1035 59/18639 0.0677966101694915 1.22092851879145 0.416192581923168 0.798689117548291 GO:1902936 phosphatidylinositol bisphosphate binding 7/1035 111/18639 0.0630630630630631 1.13568350959655 0.420740781137572 0.798689117548291 GO:0015293 symporter activity 9/1035 146/18639 0.0616438356164384 1.11012507444908 0.422836406435804 0.798689117548291 GO:0016410 N-acyltransferase activity 6/1035 94/18639 0.0638297872340425 1.14949121184089 0.423669462177132 0.798689117548291 GO:0005112 Notch binding 2/1035 26/18639 0.0769230769230769 1.38528428093645 0.427572643629221 0.798689117548291 GO:0008157 protein phosphatase 1 binding 2/1035 26/18639 0.0769230769230769 1.38528428093645 0.427572643629221 0.798689117548291 GO:0008198 ferrous iron binding 2/1035 26/18639 0.0769230769230769 1.38528428093645 0.427572643629221 0.798689117548291 GO:0030507 spectrin binding 2/1035 26/18639 0.0769230769230769 1.38528428093645 0.427572643629221 0.798689117548291 GO:0050750 low-density lipoprotein particle receptor binding 2/1035 26/18639 0.0769230769230769 1.38528428093645 0.427572643629221 0.798689117548291 GO:0070412 R-SMAD binding 2/1035 26/18639 0.0769230769230769 1.38528428093645 0.427572643629221 0.798689117548291 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 8/1035 130/18639 0.0615384615384615 1.10822742474916 0.434830598085766 0.798689117548291 GO:0001094 TFIID-class transcription factor complex binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0004090 carbonyl reductase (NADPH) activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0005381 iron ion transmembrane transporter activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0005528 FK506 binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0015187 glycine transmembrane transporter activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0015203 polyamine transmembrane transporter activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0015643 toxic substance binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0031434 mitogen-activated protein kinase kinase binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0042975 peroxisome proliferator activated receptor binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0043121 neurotrophin binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0043295 glutathione binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0045322 unmethylated CpG binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0051864 histone H3K36 demethylase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0070739 protein-glutamic acid ligase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0070740 tubulin-glutamic acid ligase activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0099122 RNA polymerase II C-terminal domain binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:1990763 arrestin family protein binding 1/1035 10/18639 0.1 1.80086956521739 0.435289519059454 0.798689117548291 GO:0030547 signaling receptor inhibitor activity 3/1035 44/18639 0.0681818181818182 1.22786561264822 0.444941954907097 0.807872109117108 GO:0008237 metallopeptidase activity 11/1035 184/18639 0.0597826086956522 1.07660680529301 0.444978798723153 0.807872109117108 GO:0001671 ATPase activator activity 2/1035 27/18639 0.0740740740740741 1.33397745571659 0.446807351541085 0.807872109117108 GO:0004364 glutathione transferase activity 2/1035 27/18639 0.0740740740740741 1.33397745571659 0.446807351541085 0.807872109117108 GO:0008266 poly(U) RNA binding 2/1035 27/18639 0.0740740740740741 1.33397745571659 0.446807351541085 0.807872109117108 GO:0008320 protein transmembrane transporter activity 2/1035 27/18639 0.0740740740740741 1.33397745571659 0.446807351541085 0.807872109117108 GO:0015252 proton channel activity 2/1035 27/18639 0.0740740740740741 1.33397745571659 0.446807351541085 0.807872109117108 GO:0033293 monocarboxylic acid binding 5/1035 79/18639 0.0632911392405063 1.13979086406164 0.448518966176214 0.807872109117108 GO:0042605 peptide antigen binding 3/1035 45/18639 0.0666666666666667 1.20057971014493 0.459663046215237 0.807872109117108 GO:0051019 mitogen-activated protein kinase binding 2/1035 28/18639 0.0714285714285714 1.28633540372671 0.46567323442957 0.807872109117108 GO:0051393 alpha-actinin binding 2/1035 28/18639 0.0714285714285714 1.28633540372671 0.46567323442957 0.807872109117108 GO:0097718 disordered domain specific binding 2/1035 28/18639 0.0714285714285714 1.28633540372671 0.46567323442957 0.807872109117108 GO:0015294 solute:monoatomic cation symporter activity 7/1035 116/18639 0.0603448275862069 1.08673163418291 0.466394241799297 0.807872109117108 GO:0003953 NAD+ nucleosidase activity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0005225 volume-sensitive anion channel activity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0008172 S-methyltransferase activity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0008199 ferric iron binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0019215 intermediate filament binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0034056 estrogen response element binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0034511 U3 snoRNA binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0035252 UDP-xylosyltransferase activity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0042285 xylosyltransferase activity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0042608 T cell receptor binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0045294 alpha-catenin binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0050786 RAGE receptor binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0070990 snRNP binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0097493 structural molecule activity conferring elasticity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:1900750 oligopeptide binding 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:1990948 ubiquitin ligase inhibitor activity 1/1035 11/18639 0.0909090909090909 1.63715415019763 0.466664007640347 0.807872109117108 GO:0051087 protein-folding chaperone binding 8/1035 134/18639 0.0597014925373134 1.07514600908501 0.468730209334717 0.810061951516922 GO:0004181 metallocarboxypeptidase activity 2/1035 29/18639 0.0689655172413793 1.24197901049475 0.484151923264698 0.829349145174439 GO:0035250 UDP-galactosyltransferase activity 2/1035 29/18639 0.0689655172413793 1.24197901049475 0.484151923264698 0.829349145174439 GO:0051861 glycolipid binding 2/1035 29/18639 0.0689655172413793 1.24197901049475 0.484151923264698 0.829349145174439 GO:0022853 active monoatomic ion transmembrane transporter activity 7/1035 118/18639 0.0593220338983051 1.06831245394252 0.484433063391182 0.829349145174439 GO:0120013 lipid transfer activity 4/1035 65/18639 0.0615384615384615 1.10822742474916 0.490673656612579 0.829349145174439 GO:0003995 acyl-CoA dehydrogenase activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0004000 adenosine deaminase activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0004126 cytidine deaminase activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0004859 phospholipase inhibitor activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0005078 MAP-kinase scaffold activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0005165 neurotrophin receptor binding 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0005436 sodium:phosphate symporter activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0005527 macrolide binding 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0015166 polyol transmembrane transporter activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0035497 cAMP response element binding 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0070008 serine-type exopeptidase activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0070410 co-SMAD binding 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0097371 MDM2/MDM4 family protein binding 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1035 12/18639 0.0833333333333333 1.50072463768116 0.49629696620231 0.829349145174439 GO:0001968 fibronectin binding 2/1035 30/18639 0.0666666666666667 1.20057971014493 0.502228221522157 0.829772289068679 GO:0008187 poly-pyrimidine tract binding 2/1035 30/18639 0.0666666666666667 1.20057971014493 0.502228221522157 0.829772289068679 GO:0016769 transferase activity, transferring nitrogenous groups 2/1035 30/18639 0.0666666666666667 1.20057971014493 0.502228221522157 0.829772289068679 GO:0031210 phosphatidylcholine binding 2/1035 30/18639 0.0666666666666667 1.20057971014493 0.502228221522157 0.829772289068679 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/1035 30/18639 0.0666666666666667 1.20057971014493 0.502228221522157 0.829772289068679 GO:0051721 protein phosphatase 2A binding 2/1035 30/18639 0.0666666666666667 1.20057971014493 0.502228221522157 0.829772289068679 GO:0032182 ubiquitin-like protein binding 7/1035 120/18639 0.0583333333333333 1.05050724637681 0.502295391602405 0.829772289068679 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1035 67/18639 0.0597014925373134 1.07514600908501 0.514640123516419 0.840019191332418 GO:0008236 serine-type peptidase activity 11/1035 194/18639 0.0567010309278351 1.02111160914388 0.515857255179298 0.840019191332418 GO:0004252 serine-type endopeptidase activity 10/1035 176/18639 0.0568181818181818 1.02322134387352 0.516647496897116 0.840019191332418 GO:0005452 solute:inorganic anion antiporter activity 2/1035 31/18639 0.0645161290322581 1.16185133239832 0.519889810084594 0.840019191332418 GO:0016878 acid-thiol ligase activity 2/1035 31/18639 0.0645161290322581 1.16185133239832 0.519889810084594 0.840019191332418 GO:0002161 aminoacyl-tRNA editing activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0008035 high-density lipoprotein particle binding 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0008253 5'-nucleotidase activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0008417 fucosyltransferase activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0019104 DNA N-glycosylase activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0031432 titin binding 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0035673 oligopeptide transmembrane transporter activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0045159 myosin II binding 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0061459 L-arginine transmembrane transporter activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0071837 HMG box domain binding 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0140333 glycerophospholipid flippase activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1035 13/18639 0.0769230769230769 1.38528428093645 0.524284975005693 0.840019191332418 GO:1990841 promoter-specific chromatin binding 4/1035 68/18639 0.0588235294117647 1.05933503836317 0.526425912206258 0.842114869051466 GO:0008081 phosphoric diester hydrolase activity 5/1035 87/18639 0.0574712643678161 1.03498250874563 0.534014753434497 0.849197775229592 GO:0016758 hexosyltransferase activity 11/1035 197/18639 0.0558375634517767 1.005561686162 0.536640172102899 0.849197775229592 GO:0008378 galactosyltransferase activity 2/1035 32/18639 0.0625 1.12554347826087 0.537126975082675 0.849197775229592 GO:0030515 snoRNA binding 2/1035 32/18639 0.0625 1.12554347826087 0.537126975082675 0.849197775229592 GO:0070717 poly-purine tract binding 2/1035 32/18639 0.0625 1.12554347826087 0.537126975082675 0.849197775229592 GO:0002039 p53 binding 4/1035 69/18639 0.0579710144927536 1.04398235664776 0.538071153866037 0.849197775229592 GO:0004866 endopeptidase inhibitor activity 9/1035 161/18639 0.0559006211180124 1.00669727248177 0.540530155312049 0.849197775229592 GO:0017171 serine hydrolase activity 11/1035 198/18639 0.0555555555555556 1.00048309178744 0.54350093182781 0.849197775229592 GO:0016597 amino acid binding 3/1035 51/18639 0.0588235294117647 1.05933503836317 0.544010522821401 0.849197775229592 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1035 70/18639 0.0571428571428571 1.02906832298137 0.54956979671577 0.849197775229592 GO:0004705 JUN kinase activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0005161 platelet-derived growth factor receptor binding 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0008191 metalloendopeptidase inhibitor activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0015386 potassium:proton antiporter activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0015926 glucosidase activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0019992 diacylglycerol binding 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0031404 chloride ion binding 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0032036 myosin heavy chain binding 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0032454 histone H3K9 demethylase activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0046030 inositol trisphosphate phosphatase activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0071933 Arp2/3 complex binding 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:1901474 azole transmembrane transporter activity 1/1035 14/18639 0.0714285714285714 1.28633540372671 0.550719263144268 0.849197775229592 GO:0019955 cytokine binding 8/1035 144/18639 0.0555555555555556 1.00048309178744 0.551012601929389 0.849197775229592 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1035 33/18639 0.0606060606060606 1.09143610013175 0.553932357042017 0.849811248815598 GO:0071889 14-3-3 protein binding 2/1035 33/18639 0.0606060606060606 1.09143610013175 0.553932357042017 0.849811248815598 GO:0140311 protein sequestering activity 2/1035 33/18639 0.0606060606060606 1.09143610013175 0.553932357042017 0.849811248815598 GO:0016829 lyase activity 11/1035 200/18639 0.055 0.990478260869565 0.557111915206528 0.852410923320848 GO:0005080 protein kinase C binding 3/1035 52/18639 0.0576923076923077 1.03896321070234 0.557313175385837 0.852410923320848 GO:0015020 glucuronosyltransferase activity 2/1035 34/18639 0.0588235294117647 1.05933503836317 0.570300719812528 0.854652791211776 GO:0015035 protein-disulfide reductase activity 2/1035 34/18639 0.0588235294117647 1.05933503836317 0.570300719812528 0.854652791211776 GO:0030332 cyclin binding 2/1035 34/18639 0.0588235294117647 1.05933503836317 0.570300719812528 0.854652791211776 GO:0051427 hormone receptor binding 2/1035 34/18639 0.0588235294117647 1.05933503836317 0.570300719812528 0.854652791211776 GO:0005246 calcium channel regulator activity 3/1035 53/18639 0.0566037735849057 1.01936013125513 0.570379791214072 0.854652791211776 GO:0003924 GTPase activity 18/1035 331/18639 0.054380664652568 0.979324839091029 0.571241026917909 0.854652791211776 GO:0031490 chromatin DNA binding 7/1035 128/18639 0.0546875 0.984850543478261 0.571411065398008 0.854652791211776 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/1035 91/18639 0.0549450549450549 0.989488772097468 0.574450047743278 0.854652791211776 GO:0072341 modified amino acid binding 5/1035 91/18639 0.0549450549450549 0.989488772097468 0.574450047743278 0.854652791211776 GO:0004129 cytochrome-c oxidase activity 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0004559 alpha-mannosidase activity 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0008252 nucleotidase activity 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0010181 FMN binding 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0015929 hexosaminidase activity 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0016846 carbon-sulfur lyase activity 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0031386 protein tag activity 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0051371 muscle alpha-actinin binding 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0120283 protein serine/threonine kinase binding 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0141047 molecular tag activity 1/1035 15/18639 0.0666666666666667 1.20057971014493 0.575686004762828 0.854652791211776 GO:0003925 G protein activity 3/1035 54/18639 0.0555555555555556 1.00048309178744 0.583204838567012 0.856161060078383 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/1035 54/18639 0.0555555555555556 1.00048309178744 0.583204838567012 0.856161060078383 GO:0050661 NADP binding 3/1035 54/18639 0.0555555555555556 1.00048309178744 0.583204838567012 0.856161060078383 GO:0051287 NAD binding 3/1035 54/18639 0.0555555555555556 1.00048309178744 0.583204838567012 0.856161060078383 GO:0140463 chromatin-protein adaptor activity 3/1035 54/18639 0.0555555555555556 1.00048309178744 0.583204838567012 0.856161060078383 GO:0043015 gamma-tubulin binding 2/1035 35/18639 0.0571428571428571 1.02906832298137 0.586228737859999 0.856161060078383 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/1035 130/18639 0.0538461538461538 0.969698996655518 0.587983237387994 0.856161060078383 GO:0005201 extracellular matrix structural constituent 9/1035 168/18639 0.0535714285714286 0.964751552795031 0.592385589773981 0.856161060078383 GO:0051213 dioxygenase activity 5/1035 93/18639 0.0537634408602151 0.968209443665264 0.593961512441448 0.856161060078383 GO:0003678 DNA helicase activity 4/1035 74/18639 0.0540540540540541 0.973443008225617 0.593994324673482 0.856161060078383 GO:0031491 nucleosome binding 4/1035 74/18639 0.0540540540540541 0.973443008225617 0.593994324673482 0.856161060078383 GO:0031406 carboxylic acid binding 10/1035 187/18639 0.053475935828877 0.963031853057429 0.594662244081588 0.856161060078383 GO:0030246 carbohydrate binding 15/1035 280/18639 0.0535714285714286 0.964751552795031 0.594797552130118 0.856161060078383 GO:0004707 MAP kinase activity 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0005521 lamin binding 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0008296 3'-5'-DNA exonuclease activity 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0015385 sodium:proton antiporter activity 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0019841 retinol binding 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0030275 LRR domain binding 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0043023 ribosomal large subunit binding 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0055102 lipase inhibitor activity 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0140327 flippase activity 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0140328 floppase activity 1/1035 16/18639 0.0625 1.12554347826087 0.599266598892471 0.856161060078383 GO:0030414 peptidase inhibitor activity 9/1035 169/18639 0.0532544378698225 0.959042963725238 0.599566795781894 0.856161060078383 GO:0016409 palmitoyltransferase activity 2/1035 36/18639 0.0555555555555556 1.00048309178744 0.60171480059623 0.856807976623645 GO:0055106 ubiquitin-protein transferase regulator activity 2/1035 36/18639 0.0555555555555556 1.00048309178744 0.60171480059623 0.856807976623645 GO:0061134 peptidase regulator activity 12/1035 226/18639 0.0530973451327434 0.956213928434013 0.605423283480897 0.860623059288789 GO:0019212 phosphatase inhibitor activity 3/1035 56/18639 0.0535714285714286 0.964751552795031 0.608112170436897 0.860623059288789 GO:0043177 organic acid binding 10/1035 189/18639 0.0529100529100529 0.952841039797562 0.608215004806756 0.860623059288789 GO:0004867 serine-type endopeptidase inhibitor activity 5/1035 95/18639 0.0526315789473684 0.947826086956522 0.612965678539075 0.860623059288789 GO:0017022 myosin binding 4/1035 76/18639 0.0526315789473684 0.947826086956522 0.615204586080711 0.860623059288789 GO:0019213 deacetylase activity 2/1035 37/18639 0.0540540540540541 0.973443008225617 0.616758832514154 0.860623059288789 GO:0042805 actinin binding 2/1035 37/18639 0.0540540540540541 0.973443008225617 0.616758832514154 0.860623059288789 GO:0016504 peptidase activator activity 3/1035 57/18639 0.0526315789473684 0.947826086956522 0.620187325618867 0.860623059288789 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0008484 sulfuric ester hydrolase activity 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0015278 intracellularly gated calcium channel activity 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0017110 nucleoside diphosphate phosphatase activity 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0030548 acetylcholine receptor regulator activity 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0032977 membrane insertase activity 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0036041 long-chain fatty acid binding 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0045125 bioactive lipid receptor activity 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0045236 CXCR chemokine receptor binding 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0048038 quinone binding 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0070403 NAD+ binding 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0070492 oligosaccharide binding 1/1035 17/18639 0.0588235294117647 1.05933503836317 0.621537933808773 0.860623059288789 GO:0004896 cytokine receptor activity 5/1035 96/18639 0.0520833333333333 0.937952898550725 0.622270481048571 0.860623059288789 GO:0000146 microfilament motor activity 2/1035 38/18639 0.0526315789473684 0.947826086956522 0.631362127978715 0.870814613078418 GO:0005109 frizzled binding 2/1035 38/18639 0.0526315789473684 0.947826086956522 0.631362127978715 0.870814613078418 GO:0015291 secondary active transmembrane transporter activity 15/1035 287/18639 0.0522648083623693 0.941221027117104 0.633189143251492 0.872144719110706 GO:0140375 immune receptor activity 8/1035 156/18639 0.0512820512820513 0.923522853957637 0.64198368954507 0.873352050154293 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:0005372 water transmembrane transporter activity 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:0008308 voltage-gated monoatomic anion channel activity 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:0008409 5'-3' exonuclease activity 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:0017075 syntaxin-1 binding 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:0098641 cadherin binding involved in cell-cell adhesion 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:0099602 neurotransmitter receptor regulator activity 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:1990381 ubiquitin-specific protease binding 1/1035 18/18639 0.0555555555555556 1.00048309178744 0.642572636768065 0.873352050154293 GO:0015459 potassium channel regulator activity 3/1035 59/18639 0.0508474576271186 0.915696389093589 0.643568029045448 0.873352050154293 GO:0036002 pre-mRNA binding 3/1035 59/18639 0.0508474576271186 0.915696389093589 0.643568029045448 0.873352050154293 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/1035 39/18639 0.0512820512820513 0.923522853957637 0.645527199602897 0.874836459515455 GO:0043021 ribonucleoprotein complex binding 9/1035 177/18639 0.0508474576271186 0.915696389093589 0.654667045866289 0.875459009593527 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/1035 60/18639 0.05 0.900434782608696 0.654870460483048 0.875459009593527 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/1035 60/18639 0.05 0.900434782608696 0.654870460483048 0.875459009593527 GO:0000049 tRNA binding 4/1035 80/18639 0.05 0.900434782608696 0.655496260344097 0.875459009593527 GO:0043130 ubiquitin binding 5/1035 100/18639 0.05 0.900434782608696 0.658121963891453 0.875459009593527 GO:0015036 disulfide oxidoreductase activity 2/1035 40/18639 0.05 0.900434782608696 0.659257639211923 0.875459009593527 GO:0032451 demethylase activity 2/1035 40/18639 0.05 0.900434782608696 0.659257639211923 0.875459009593527 GO:0050997 quaternary ammonium group binding 2/1035 40/18639 0.05 0.900434782608696 0.659257639211923 0.875459009593527 GO:0005319 lipid transporter activity 9/1035 178/18639 0.050561797752809 0.910552027357108 0.661241548596633 0.875459009593527 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0016918 retinal binding 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0022821 solute:potassium antiporter activity 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0030506 ankyrin binding 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0070003 threonine-type peptidase activity 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0097001 ceramide binding 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0140036 ubiquitin-modified protein reader activity 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0141147 intracellularly calcium-gated channel activity 1/1035 19/18639 0.0526315789473684 0.947826086956522 0.66243930992982 0.875459009593527 GO:0005126 cytokine receptor binding 14/1035 275/18639 0.0509090909090909 0.916806324110672 0.669707943292093 0.883059906964088 GO:0001530 lipopolysaccharide binding 2/1035 41/18639 0.0487804878048781 0.87847295864263 0.672557990467208 0.883059906964088 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1035 41/18639 0.0487804878048781 0.87847295864263 0.672557990467208 0.883059906964088 GO:0042287 MHC protein binding 2/1035 41/18639 0.0487804878048781 0.87847295864263 0.672557990467208 0.883059906964088 GO:0140318 protein transporter activity 2/1035 41/18639 0.0487804878048781 0.87847295864263 0.672557990467208 0.883059906964088 GO:0016853 isomerase activity 9/1035 180/18639 0.05 0.900434782608696 0.67417007362287 0.884028462299249 GO:0015171 amino acid transmembrane transporter activity 5/1035 102/18639 0.0490196078431373 0.882779198635976 0.675202983258868 0.884077000659923 GO:0000339 RNA cap binding 1/1035 20/18639 0.05 0.900434782608696 0.681202753228566 0.884077000659923 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/1035 20/18639 0.05 0.900434782608696 0.681202753228566 0.884077000659923 GO:0015095 magnesium ion transmembrane transporter activity 1/1035 20/18639 0.05 0.900434782608696 0.681202753228566 0.884077000659923 GO:0016408 C-acyltransferase activity 1/1035 20/18639 0.05 0.900434782608696 0.681202753228566 0.884077000659923 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1035 20/18639 0.05 0.900434782608696 0.681202753228566 0.884077000659923 GO:0042288 MHC class I protein binding 1/1035 20/18639 0.05 0.900434782608696 0.681202753228566 0.884077000659923 GO:0052745 inositol phosphate phosphatase activity 1/1035 20/18639 0.05 0.900434782608696 0.681202753228566 0.884077000659923 GO:0035198 miRNA binding 2/1035 42/18639 0.0476190476190476 0.857556935817805 0.685433632285902 0.887289887632583 GO:0042056 chemoattractant activity 2/1035 42/18639 0.0476190476190476 0.857556935817805 0.685433632285902 0.887289887632583 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1035 21/18639 0.0476190476190476 0.857556935817805 0.698924174916542 0.896716168579472 GO:0005123 death receptor binding 1/1035 21/18639 0.0476190476190476 0.857556935817805 0.698924174916542 0.896716168579472 GO:0005248 voltage-gated sodium channel activity 1/1035 21/18639 0.0476190476190476 0.857556935817805 0.698924174916542 0.896716168579472 GO:0008373 sialyltransferase activity 1/1035 21/18639 0.0476190476190476 0.857556935817805 0.698924174916542 0.896716168579472 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1035 21/18639 0.0476190476190476 0.857556935817805 0.698924174916542 0.896716168579472 GO:0051428 peptide hormone receptor binding 1/1035 21/18639 0.0476190476190476 0.857556935817805 0.698924174916542 0.896716168579472 GO:1904047 S-adenosyl-L-methionine binding 1/1035 21/18639 0.0476190476190476 0.857556935817805 0.698924174916542 0.896716168579472 GO:0005525 GTP binding 19/1035 378/18639 0.0502645502645503 0.905198987807683 0.70628160635149 0.902161677997019 GO:0038024 cargo receptor activity 3/1035 65/18639 0.0461538461538462 0.831170568561873 0.707490719959461 0.902161677997019 GO:0160215 deacylase activity 3/1035 65/18639 0.0461538461538462 0.831170568561873 0.707490719959461 0.902161677997019 GO:0004497 monooxygenase activity 5/1035 106/18639 0.0471698113207547 0.849466776045939 0.707630536294164 0.902161677997019 GO:0015399 primary active transmembrane transporter activity 8/1035 166/18639 0.0481927710843374 0.867888947092719 0.709152662694672 0.902161677997019 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1035 44/18639 0.0454545454545455 0.818577075098814 0.709935849268037 0.902161677997019 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/1035 86/18639 0.0465116279069767 0.837613751263903 0.710414429271571 0.902161677997019 GO:0008093 cytoskeletal anchor activity 1/1035 22/18639 0.0454545454545455 0.818577075098814 0.715661390458565 0.902161677997019 GO:0016881 acid-amino acid ligase activity 1/1035 22/18639 0.0454545454545455 0.818577075098814 0.715661390458565 0.902161677997019 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1035 22/18639 0.0454545454545455 0.818577075098814 0.715661390458565 0.902161677997019 GO:0034062 5'-3' RNA polymerase activity 1/1035 22/18639 0.0454545454545455 0.818577075098814 0.715661390458565 0.902161677997019 GO:0097747 RNA polymerase activity 1/1035 22/18639 0.0454545454545455 0.818577075098814 0.715661390458565 0.902161677997019 GO:0140035 ubiquitin-like protein reader activity 1/1035 22/18639 0.0454545454545455 0.818577075098814 0.715661390458565 0.902161677997019 GO:0140517 protein-RNA adaptor activity 1/1035 22/18639 0.0454545454545455 0.818577075098814 0.715661390458565 0.902161677997019 GO:0022804 active transmembrane transporter activity 23/1035 457/18639 0.050328227571116 0.906345733041576 0.717618637097114 0.903502418561871 GO:0008009 chemokine activity 2/1035 45/18639 0.0444444444444444 0.800386473429952 0.721576444758866 0.907355454790066 GO:0004843 cysteine-type deubiquitinase activity 5/1035 108/18639 0.0462962962962963 0.833735909822866 0.72296846247514 0.907380576119653 GO:0008509 monoatomic anion transmembrane transporter activity 7/1035 149/18639 0.0469798657718121 0.846046104464546 0.727329787146586 0.907380576119653 GO:0004620 phospholipase activity 5/1035 109/18639 0.0458715596330275 0.826086956521739 0.730417965008352 0.907380576119653 GO:0003887 DNA-directed DNA polymerase activity 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0005212 structural constituent of eye lens 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0005283 amino acid:sodium symporter activity 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0008171 O-methyltransferase activity 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0016493 C-C chemokine receptor activity 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0017134 fibroblast growth factor binding 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0043274 phospholipase binding 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1035 23/18639 0.0434782608695652 0.782986767485822 0.731469010422865 0.907380576119653 GO:0005548 phospholipid transporter activity 3/1035 68/18639 0.0441176470588235 0.794501278772379 0.735983841337809 0.911862332833976 GO:0043495 protein-membrane adaptor activity 2/1035 47/18639 0.0425531914893617 0.766327474560592 0.743675251350745 0.912013820952603 GO:0140359 ABC-type transporter activity 2/1035 47/18639 0.0425531914893617 0.766327474560592 0.743675251350745 0.912013820952603 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/1035 24/18639 0.0416666666666667 0.75036231884058 0.746398617976171 0.912013820952603 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1035 24/18639 0.0416666666666667 0.75036231884058 0.746398617976171 0.912013820952603 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1035 24/18639 0.0416666666666667 0.75036231884058 0.746398617976171 0.912013820952603 GO:0004622 lysophospholipase activity 1/1035 24/18639 0.0416666666666667 0.75036231884058 0.746398617976171 0.912013820952603 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1035 24/18639 0.0416666666666667 0.75036231884058 0.746398617976171 0.912013820952603 GO:0048027 mRNA 5'-UTR binding 1/1035 24/18639 0.0416666666666667 0.75036231884058 0.746398617976171 0.912013820952603 GO:0050699 WW domain binding 1/1035 24/18639 0.0416666666666667 0.75036231884058 0.746398617976171 0.912013820952603 GO:0097110 scaffold protein binding 3/1035 70/18639 0.0428571428571429 0.771801242236025 0.753729577476261 0.912013820952603 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/1035 48/18639 0.0416666666666667 0.75036231884058 0.754150045716581 0.912013820952603 GO:0032266 phosphatidylinositol-3-phosphate binding 2/1035 48/18639 0.0416666666666667 0.75036231884058 0.754150045716581 0.912013820952603 GO:0003707 nuclear steroid receptor activity 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0005537 D-mannose binding 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0008483 transaminase activity 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0015271 outward rectifier potassium channel activity 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0017025 TBP-class protein binding 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0019707 protein-cysteine S-acyltransferase activity 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0047617 fatty acyl-CoA hydrolase activity 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1035 25/18639 0.04 0.720347826086957 0.760498936557673 0.912013820952603 GO:0015297 antiporter activity 6/1035 135/18639 0.0444444444444444 0.800386473429952 0.766946442218364 0.912013820952603 GO:0042379 chemokine receptor binding 3/1035 72/18639 0.0416666666666667 0.75036231884058 0.770502590451918 0.912013820952603 GO:0101005 deubiquitinase activity 5/1035 115/18639 0.0434782608695652 0.782986767485822 0.772064908644216 0.912013820952603 GO:0019838 growth factor binding 6/1035 136/18639 0.0441176470588235 0.794501278772379 0.773004609012823 0.912013820952603 GO:0044325 transmembrane transporter binding 6/1035 136/18639 0.0441176470588235 0.794501278772379 0.773004609012823 0.912013820952603 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0004529 DNA exonuclease activity 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0004950 chemokine receptor activity 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0005160 transforming growth factor beta receptor binding 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0005227 calcium-activated cation channel activity 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0008143 poly(A) binding 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0016289 acyl-CoA hydrolase activity 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0034237 protein kinase A regulatory subunit binding 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0051139 metal cation:proton antiporter activity 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0097602 cullin family protein binding 1/1035 26/18639 0.0384615384615385 0.692642140468227 0.773815988274811 0.912013820952603 GO:0015605 organophosphate ester transmembrane transporter activity 2/1035 50/18639 0.04 0.720347826086957 0.773993925200132 0.912013820952603 GO:0032813 tumor necrosis factor receptor superfamily binding 2/1035 50/18639 0.04 0.720347826086957 0.773993925200132 0.912013820952603 GO:0048020 CCR chemokine receptor binding 2/1035 50/18639 0.04 0.720347826086957 0.773993925200132 0.912013820952603 GO:0009055 electron transfer activity 5/1035 116/18639 0.0431034482758621 0.77623688155922 0.778504127150036 0.916260387134676 GO:0016405 CoA-ligase activity 1/1035 27/18639 0.037037037037037 0.666988727858293 0.786393243533801 0.923395550769654 GO:0035255 ionotropic glutamate receptor binding 1/1035 27/18639 0.037037037037037 0.666988727858293 0.786393243533801 0.923395550769654 GO:0019001 guanyl nucleotide binding 19/1035 400/18639 0.0475 0.855413043478261 0.790800377209131 0.926418518375935 GO:0032561 guanyl ribonucleotide binding 19/1035 400/18639 0.0475 0.855413043478261 0.790800377209131 0.926418518375935 GO:0030159 signaling receptor complex adaptor activity 2/1035 52/18639 0.0384615384615385 0.692642140468227 0.79242371594674 0.927233641373207 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/1035 181/18639 0.0441988950276243 0.795964448714869 0.793330464676383 0.927233641373207 GO:0046625 sphingolipid binding 1/1035 28/18639 0.0357142857142857 0.643167701863354 0.798271762389513 0.927770636159722 GO:0141052 histone H3 demethylase activity 1/1035 28/18639 0.0357142857142857 0.643167701863354 0.798271762389513 0.927770636159722 GO:0004864 protein phosphatase inhibitor activity 2/1035 53/18639 0.0377358490566038 0.679573420836751 0.801131320838217 0.927770636159722 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/1035 53/18639 0.0377358490566038 0.679573420836751 0.801131320838217 0.927770636159722 GO:0017046 peptide hormone binding 2/1035 53/18639 0.0377358490566038 0.679573420836751 0.801131320838217 0.927770636159722 GO:0051018 protein kinase A binding 2/1035 53/18639 0.0377358490566038 0.679573420836751 0.801131320838217 0.927770636159722 GO:0140296 general transcription initiation factor binding 2/1035 53/18639 0.0377358490566038 0.679573420836751 0.801131320838217 0.927770636159722 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/1035 53/18639 0.0377358490566038 0.679573420836751 0.801131320838217 0.927770636159722 GO:0020037 heme binding 6/1035 142/18639 0.0422535211267606 0.760930802204531 0.806890563884005 0.931078217079266 GO:0005416 amino acid:monoatomic cation symporter activity 1/1035 29/18639 0.0344827586206897 0.620989505247376 0.809490328072542 0.931078217079266 GO:0016417 S-acyltransferase activity 1/1035 29/18639 0.0344827586206897 0.620989505247376 0.809490328072542 0.931078217079266 GO:0043236 laminin binding 1/1035 29/18639 0.0344827586206897 0.620989505247376 0.809490328072542 0.931078217079266 GO:0099604 ligand-gated calcium channel activity 1/1035 29/18639 0.0344827586206897 0.620989505247376 0.809490328072542 0.931078217079266 GO:0017069 snRNA binding 2/1035 54/18639 0.037037037037037 0.666988727858293 0.809513108617878 0.931078217079266 GO:0015103 inorganic anion transmembrane transporter activity 7/1035 165/18639 0.0424242424242424 0.764005270092227 0.816546130193978 0.935786133668611 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/1035 268/18639 0.0447761194029851 0.806359506813757 0.816744780869028 0.935786133668611 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/1035 30/18639 0.0333333333333333 0.600289855072464 0.820085573126003 0.935786133668611 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1035 30/18639 0.0333333333333333 0.600289855072464 0.820085573126003 0.935786133668611 GO:0022839 monoatomic ion-gated channel activity 1/1035 30/18639 0.0333333333333333 0.600289855072464 0.820085573126003 0.935786133668611 GO:0032452 histone demethylase activity 1/1035 30/18639 0.0333333333333333 0.600289855072464 0.820085573126003 0.935786133668611 GO:0048019 receptor antagonist activity 1/1035 30/18639 0.0333333333333333 0.600289855072464 0.820085573126003 0.935786133668611 GO:0015370 solute:sodium symporter activity 3/1035 79/18639 0.0379746835443038 0.683874518436984 0.821964914205471 0.936873199844117 GO:0005164 tumor necrosis factor receptor binding 1/1035 31/18639 0.032258064516129 0.580925666199159 0.830092098560717 0.941399680355481 GO:0008327 methyl-CpG binding 1/1035 31/18639 0.032258064516129 0.580925666199159 0.830092098560717 0.941399680355481 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1035 31/18639 0.032258064516129 0.580925666199159 0.830092098560717 0.941399680355481 GO:0140457 protein demethylase activity 1/1035 31/18639 0.032258064516129 0.580925666199159 0.830092098560717 0.941399680355481 GO:0005253 monoatomic anion channel activity 4/1035 103/18639 0.0388349514563107 0.699366821443647 0.830592002845785 0.941399680355481 GO:0004601 peroxidase activity 2/1035 57/18639 0.0350877192982456 0.631884057971015 0.832796345882585 0.941786471686011 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/1035 57/18639 0.0350877192982456 0.631884057971015 0.832796345882585 0.941786471686011 GO:0015106 bicarbonate transmembrane transporter activity 1/1035 32/18639 0.03125 0.562771739130435 0.839542586414847 0.944612959918843 GO:0031369 translation initiation factor binding 1/1035 32/18639 0.03125 0.562771739130435 0.839542586414847 0.944612959918843 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1035 32/18639 0.03125 0.562771739130435 0.839542586414847 0.944612959918843 GO:0043425 bHLH transcription factor binding 1/1035 32/18639 0.03125 0.562771739130435 0.839542586414847 0.944612959918843 GO:0061980 regulatory RNA binding 2/1035 58/18639 0.0344827586206897 0.620989505247376 0.839967409462947 0.944612959918843 GO:0030165 PDZ domain binding 3/1035 83/18639 0.036144578313253 0.650916710319539 0.846704314637238 0.948216943340652 GO:0008013 beta-catenin binding 4/1035 106/18639 0.0377358490566038 0.679573420836751 0.846801285990849 0.948216943340652 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/1035 59/18639 0.0338983050847458 0.610464259395726 0.846858615793386 0.948216943340652 GO:0001664 G protein-coupled receptor binding 13/1035 297/18639 0.0437710437710438 0.78825940565071 0.84692373871079 0.948216943340652 GO:0042923 neuropeptide binding 1/1035 33/18639 0.0303030303030303 0.545718050065876 0.848467906082748 0.948894970187675 GO:0001217 DNA-binding transcription repressor activity 12/1035 278/18639 0.0431654676258993 0.777353769158586 0.851869684347273 0.951646686049827 GO:0046906 tetrapyrrole binding 6/1035 152/18639 0.0394736842105263 0.710869565217391 0.854431421312684 0.952486023781706 GO:0016298 lipase activity 5/1035 130/18639 0.0384615384615385 0.692642140468227 0.854505265647881 0.952486023781706 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1035 34/18639 0.0294117647058824 0.529667519181586 0.856897214757603 0.95410031290742 GO:0003774 cytoskeletal motor activity 6/1035 153/18639 0.0392156862745098 0.706223358908781 0.858609057160561 0.954954627931053 GO:0016836 hydro-lyase activity 2/1035 61/18639 0.0327868852459016 0.590449037776194 0.859837057221608 0.955269521814336 GO:0016209 antioxidant activity 3/1035 86/18639 0.0348837209302326 0.628210313447927 0.863246370329067 0.956642769025014 GO:0005343 organic acid:sodium symporter activity 1/1035 35/18639 0.0285714285714286 0.514534161490683 0.864858052313416 0.956642769025014 GO:0016229 steroid dehydrogenase activity 1/1035 35/18639 0.0285714285714286 0.514534161490683 0.864858052313416 0.956642769025014 GO:0034061 DNA polymerase activity 1/1035 35/18639 0.0285714285714286 0.514534161490683 0.864858052313416 0.956642769025014 GO:0004222 metalloendopeptidase activity 4/1035 110/18639 0.0363636363636364 0.654861660079051 0.866359163950992 0.957255863119621 GO:0004033 aldo-keto reductase (NADPH) activity 1/1035 36/18639 0.0277777777777778 0.50024154589372 0.872376430933906 0.961802150135419 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1035 36/18639 0.0277777777777778 0.50024154589372 0.872376430933906 0.961802150135419 GO:0005200 structural constituent of cytoskeleton 4/1035 112/18639 0.0357142857142857 0.643167701863354 0.875308208026626 0.962934274553775 GO:0043022 ribosome binding 4/1035 112/18639 0.0357142857142857 0.643167701863354 0.875308208026626 0.962934274553775 GO:0004536 DNA nuclease activity 2/1035 64/18639 0.03125 0.562771739130435 0.877424665535349 0.964213409626345 GO:0022829 wide pore channel activity 1/1035 37/18639 0.027027027027027 0.486721504112808 0.8794769197789 0.965419289789867 GO:0005501 retinoid binding 1/1035 38/18639 0.0263157894736842 0.473913043478261 0.886182724962688 0.970672518891959 GO:0019840 isoprenoid binding 1/1035 38/18639 0.0263157894736842 0.473913043478261 0.886182724962688 0.970672518891959 GO:0008173 RNA methyltransferase activity 2/1035 67/18639 0.0298507462686567 0.537573004542505 0.89295539132236 0.975976108785844 GO:0016500 protein-hormone receptor activity 2/1035 67/18639 0.0298507462686567 0.537573004542505 0.89295539132236 0.975976108785844 GO:0015078 proton transmembrane transporter activity 7/1035 185/18639 0.0378378378378378 0.681410105757932 0.894099220915687 0.976170963656328 GO:0140223 general transcription initiation factor activity 2/1035 68/18639 0.0294117647058824 0.529667519181586 0.897712104958255 0.976752910602476 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/1035 40/18639 0.025 0.450217391304348 0.898496742690705 0.976752910602476 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/1035 40/18639 0.025 0.450217391304348 0.898496742690705 0.976752910602476 GO:0140662 ATP-dependent protein folding chaperone 1/1035 40/18639 0.025 0.450217391304348 0.898496742690705 0.976752910602476 GO:0042562 hormone binding 3/1035 94/18639 0.0319148936170213 0.574745605920444 0.899908692152707 0.977237043787741 GO:1901681 sulfur compound binding 11/1035 275/18639 0.04 0.720347826086957 0.902363972203513 0.977637228687435 GO:0004812 aminoacyl-tRNA ligase activity 1/1035 41/18639 0.024390243902439 0.439236479321315 0.904145211496292 0.977637228687435 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1035 41/18639 0.024390243902439 0.439236479321315 0.904145211496292 0.977637228687435 GO:0140828 metal cation:monoatomic cation antiporter activity 1/1035 41/18639 0.024390243902439 0.439236479321315 0.904145211496292 0.977637228687435 GO:0005125 cytokine activity 9/1035 234/18639 0.0384615384615385 0.692642140468227 0.907788307426842 0.97817437904293 GO:0015108 chloride transmembrane transporter activity 4/1035 121/18639 0.0330578512396694 0.595328781890047 0.909435596424223 0.97817437904293 GO:0004520 DNA endonuclease activity 1/1035 42/18639 0.0238095238095238 0.428778467908903 0.909479640257521 0.97817437904293 GO:0008307 structural constituent of muscle 1/1035 42/18639 0.0238095238095238 0.428778467908903 0.909479640257521 0.97817437904293 GO:0031492 nucleosomal DNA binding 1/1035 42/18639 0.0238095238095238 0.428778467908903 0.909479640257521 0.97817437904293 GO:0140299 molecular sensor activity 2/1035 71/18639 0.028169014084507 0.507287201469688 0.910825775741352 0.978581146944215 GO:0005245 voltage-gated calcium channel activity 1/1035 43/18639 0.0232558139534884 0.418806875631951 0.91451747282909 0.979424962955731 GO:0008375 acetylglucosaminyltransferase activity 1/1035 43/18639 0.0232558139534884 0.418806875631951 0.91451747282909 0.979424962955731 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1035 43/18639 0.0232558139534884 0.418806875631951 0.91451747282909 0.979424962955731 GO:0015085 calcium ion transmembrane transporter activity 5/1035 147/18639 0.0340136054421769 0.61254066844129 0.916299080272149 0.980294571592743 GO:0001046 core promoter sequence-specific DNA binding 1/1035 44/18639 0.0227272727272727 0.409288537549407 0.919275185004929 0.980366257426142 GO:0001223 transcription coactivator binding 1/1035 44/18639 0.0227272727272727 0.409288537549407 0.919275185004929 0.980366257426142 GO:0016790 thiolester hydrolase activity 1/1035 44/18639 0.0227272727272727 0.409288537549407 0.919275185004929 0.980366257426142 GO:0003684 damaged DNA binding 2/1035 74/18639 0.027027027027027 0.486721504112808 0.922350743963923 0.981575370681607 GO:0048029 monosaccharide binding 2/1035 74/18639 0.027027027027027 0.486721504112808 0.922350743963923 0.981575370681607 GO:0046915 transition metal ion transmembrane transporter activity 1/1035 45/18639 0.0222222222222222 0.400193236714976 0.923768338192339 0.982050252273875 GO:0044183 protein folding chaperone 2/1035 75/18639 0.0266666666666667 0.480231884057971 0.925869980202535 0.983250577715087 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1035 46/18639 0.0217391304347826 0.391493383742911 0.928011630112901 0.983458865874364 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/1035 46/18639 0.0217391304347826 0.391493383742911 0.928011630112901 0.983458865874364 GO:0099095 ligand-gated monoatomic anion channel activity 1/1035 47/18639 0.0212765957446809 0.383163737280296 0.932018942694687 0.986671362371025 GO:0005506 iron ion binding 5/1035 154/18639 0.0324675324675325 0.584697910784867 0.934125370002408 0.987866892335183 GO:0038187 pattern recognition receptor activity 1/1035 48/18639 0.0208333333333333 0.37518115942029 0.935803387311243 0.988597230363224 GO:0005262 calcium channel activity 4/1035 131/18639 0.0305343511450382 0.5498838367076 0.937391581110029 0.988597230363224 GO:0016835 carbon-oxygen lyase activity 2/1035 79/18639 0.0253164556962025 0.455916345624656 0.938495692634223 0.988597230363224 GO:0005179 hormone activity 4/1035 132/18639 0.0303030303030303 0.545718050065876 0.939705181383836 0.988597230363224 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/1035 132/18639 0.0303030303030303 0.545718050065876 0.939705181383836 0.988597230363224 GO:0003743 translation initiation factor activity 1/1035 51/18639 0.0196078431372549 0.35311167945439 0.945939949729141 0.990986804051311 GO:0005030 neurotrophin receptor activity 1/1035 51/18639 0.0196078431372549 0.35311167945439 0.945939949729141 0.990986804051311 GO:0005272 sodium channel activity 1/1035 51/18639 0.0196078431372549 0.35311167945439 0.945939949729141 0.990986804051311 GO:0015079 potassium ion transmembrane transporter activity 5/1035 160/18639 0.03125 0.562771739130435 0.946615735101973 0.990986804051311 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/1035 52/18639 0.0192307692307692 0.346321070234114 0.948950071960169 0.990986804051311 GO:0005254 chloride channel activity 2/1035 83/18639 0.0240963855421687 0.433944473546359 0.949062147350628 0.990986804051311 GO:0008083 growth factor activity 5/1035 162/18639 0.0308641975308642 0.555823939881911 0.950276882544171 0.990986804051311 GO:0008146 sulfotransferase activity 1/1035 53/18639 0.0188679245283019 0.339786710418376 0.951792740250975 0.990986804051311 GO:0046982 protein heterodimerization activity 14/1035 369/18639 0.037940379403794 0.683256745610934 0.952411545169477 0.990986804051311 GO:0046943 carboxylic acid transmembrane transporter activity 6/1035 188/18639 0.0319148936170213 0.574745605920444 0.953164132929987 0.990986804051311 GO:0015081 sodium ion transmembrane transporter activity 5/1035 164/18639 0.0304878048780488 0.549045599151644 0.953708613430561 0.990986804051311 GO:0140101 catalytic activity, acting on a tRNA 4/1035 139/18639 0.0287769784172662 0.518235846105724 0.953837050239949 0.990986804051311 GO:0005342 organic acid transmembrane transporter activity 6/1035 189/18639 0.0317460317460317 0.571704623878537 0.954719235554873 0.990986804051311 GO:0004879 nuclear receptor activity 1/1035 59/18639 0.0169491525423729 0.305232129697863 0.965818794732426 0.998351858762854 GO:0008514 organic anion transmembrane transporter activity 9/1035 269/18639 0.033457249070632 0.60252141587199 0.96608756605978 0.998351858762854 GO:0052689 carboxylic ester hydrolase activity 2/1035 92/18639 0.0217391304347826 0.391493383742911 0.966863865662599 0.998351858762854 GO:0051082 unfolded protein binding 3/1035 121/18639 0.0247933884297521 0.446496586417535 0.967348548754619 0.998351858762854 GO:0098531 ligand-modulated transcription factor activity 1/1035 60/18639 0.0166666666666667 0.300144927536232 0.967722860795501 0.998351858762854 GO:0003823 antigen binding 5/1035 174/18639 0.028735632183908 0.517491254372814 0.967841733790659 0.998351858762854 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/1035 122/18639 0.0245901639344262 0.442836778332145 0.968727174526568 0.998351858762854 GO:0005507 copper ion binding 1/1035 63/18639 0.0158730158730159 0.285852311939268 0.972822484656242 0.99999988019788 GO:1901682 sulfur compound transmembrane transporter activity 1/1035 63/18639 0.0158730158730159 0.285852311939268 0.972822484656242 0.99999988019788 GO:0005249 voltage-gated potassium channel activity 2/1035 98/18639 0.0204081632653061 0.367524401064774 0.975221884673297 0.99999988019788 GO:0019843 rRNA binding 1/1035 65/18639 0.0153846153846154 0.277056856187291 0.975766694218822 0.99999988019788 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 18/1035 484/18639 0.0371900826446281 0.669744879626303 0.975804884718057 0.99999988019788 GO:0050840 extracellular matrix binding 1/1035 67/18639 0.0149253731343284 0.268786502271252 0.978392224635562 0.99999988019788 GO:0003777 microtubule motor activity 1/1035 68/18639 0.0147058823529412 0.264833759590793 0.979596405526268 0.99999988019788 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/1035 68/18639 0.0147058823529412 0.264833759590793 0.979596405526268 0.99999988019788 GO:0001216 DNA-binding transcription activator activity 18/1035 491/18639 0.0366598778004073 0.660196581953422 0.979649340731706 0.99999988019788 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/1035 70/18639 0.0142857142857143 0.257267080745342 0.9818073570325 0.99999988019788 GO:0008201 heparin binding 4/1035 172/18639 0.0232558139534884 0.418806875631951 0.987791349662559 0.99999988019788 GO:0019842 vitamin binding 3/1035 150/18639 0.02 0.360173913043478 0.990996824228143 0.99999988019788 GO:0008135 translation factor activity, RNA binding 1/1035 83/18639 0.0120481927710843 0.21697223677318 0.991370405656914 0.99999988019788 GO:0180051 translation factor activity 1/1035 84/18639 0.0119047619047619 0.214389233954451 0.991851739465122 0.99999988019788 GO:0005267 potassium channel activity 2/1035 124/18639 0.0161290322580645 0.290462833099579 0.993174030497609 0.99999988019788 GO:0046873 metal ion transmembrane transporter activity 14/1035 450/18639 0.0311111111111111 0.560270531400966 0.99497531788529 0.99999988019788 GO:0099094 ligand-gated monoatomic cation channel activity 2/1035 136/18639 0.0147058823529412 0.264833759590793 0.996284224887238 0.99999988019788 GO:0005244 voltage-gated monoatomic ion channel activity 3/1035 173/18639 0.0173410404624277 0.312289519979894 0.99690221738771 0.99999988019788 GO:0003735 structural constituent of ribosome 3/1035 175/18639 0.0171428571428571 0.30872049689441 0.997181036275678 0.99999988019788 GO:0022832 voltage-gated channel activity 3/1035 175/18639 0.0171428571428571 0.30872049689441 0.997181036275678 0.99999988019788 GO:0022843 voltage-gated monoatomic cation channel activity 2/1035 143/18639 0.013986013986014 0.251869869261174 0.997402073732865 0.99999988019788 GO:0005216 monoatomic ion channel activity 13/1035 448/18639 0.0290178571428571 0.522573757763975 0.997497368783364 0.99999988019788 GO:0015276 ligand-gated monoatomic ion channel activity 3/1035 186/18639 0.0161290322580645 0.290462833099579 0.99832852810246 0.99999988019788 GO:0022834 ligand-gated channel activity 3/1035 188/18639 0.0159574468085106 0.287372802960222 0.998481087883509 0.99999988019788 GO:0005261 monoatomic cation channel activity 8/1035 341/18639 0.0234604105571848 0.422491393599388 0.998834129620588 0.99999988019788 GO:0005539 glycosaminoglycan binding 4/1035 242/18639 0.0165289256198347 0.297664390945023 0.999448174231702 0.99999988019788 GO:0022836 gated channel activity 6/1035 318/18639 0.0188679245283019 0.339786710418376 0.999707474366561 0.99999988019788 GO:0003730 mRNA 3'-UTR binding 4/1035 262/18639 0.0152671755725191 0.2749419183538 0.999782989997002 0.99999988019788 GO:0045182 translation regulator activity 3/1035 356/18639 0.00842696629213483 0.151758671226185 0.999999700226675 0.99999988019788 GO:0030371 translation repressor activity 2/1035 329/18639 0.0060790273556231 0.109475353508656 0.99999988019788 0.99999988019788