ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 77/1553 175/18639 0.44 5.28084996780425 3.65170305793497e-37 4.25788576555217e-34 GO:0009055 electron transfer activity 39/1553 116/18639 0.336206896551724 4.03513222461532 1.02874875780621e-14 5.99760525801022e-12 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 28/1553 68/18639 0.411764705882353 4.94197189500398 1.78657994424205e-13 6.94384071662076e-11 GO:0015078 proton transmembrane transporter activity 45/1553 185/18639 0.243243243243243 2.91938880284019 3.6165131994007e-11 1.05421359762531e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 34/1553 118/18639 0.288135593220339 3.45818372313838 6.75831891242555e-11 1.57603997037764e-08 GO:0008137 NADH dehydrogenase (ubiquinone) activity 18/1553 41/18639 0.439024390243902 5.2691407661018 1.06983089369718e-09 2.07903803675152e-07 GO:0003954 NADH dehydrogenase activity 18/1553 44/18639 0.409090909090909 4.90988116841304 4.27532227265513e-09 7.12146538559412e-07 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 19/1553 58/18639 0.327586206896552 3.93166729577903 1.12549554748406e-07 1.64040976045801e-05 GO:0015399 primary active transmembrane transporter activity 35/1553 166/18639 0.210843373493976 2.53052777756228 2.46753948592598e-07 3.1968344895441e-05 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 9/1553 18/18639 0.5 6.00096587250483 4.59528526514714e-06 0.000535810261916156 GO:0016651 oxidoreductase activity, acting on NAD(P)H 21/1553 88/18639 0.238636363636364 2.86409734824094 8.16993003363394e-06 0.000772730922342559 GO:0031386 protein tag activity 8/1553 15/18639 0.533333333333333 6.40103026400515 8.61535333658085e-06 0.000772730922342559 GO:0141047 molecular tag activity 8/1553 15/18639 0.533333333333333 6.40103026400515 8.61535333658085e-06 0.000772730922342559 GO:0050840 extracellular matrix binding 17/1553 67/18639 0.253731343283582 3.04526626365917 2.48688776709515e-05 0.00207122224030925 GO:0044389 ubiquitin-like protein ligase binding 49/1553 322/18639 0.152173913043478 1.82638091771886 2.77535982965751e-05 0.0021573797075871 GO:0019003 GDP binding 18/1553 75/18639 0.24 2.88046361880232 3.27241301611075e-05 0.00238477098549071 GO:0015252 proton channel activity 10/1553 27/18639 0.37037037037037 4.44515990555913 3.52640670009027e-05 0.00241870012488545 GO:0031625 ubiquitin protein ligase binding 46/1553 302/18639 0.152317880794702 1.82810880884253 4.7088433668417e-05 0.00305028409207635 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 11/1553 36/18639 0.305555555555556 3.66725692208629 0.00011020616908047 0.00592515365698539 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 11/1553 36/18639 0.305555555555556 3.66725692208629 0.00011020616908047 0.00592515365698539 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 11/1553 36/18639 0.305555555555556 3.66725692208629 0.00011020616908047 0.00592515365698539 GO:0016859 cis-trans isomerase activity 12/1553 42/18639 0.285714285714286 3.42912335571705 0.000111795352018592 0.00592515365698539 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 11/1553 39/18639 0.282051282051282 3.38516023577195 0.000243582293103371 0.0123485632068926 GO:0051537 2 iron, 2 sulfur cluster binding 9/1553 28/18639 0.321428571428571 3.85776377518168 0.000303435004709465 0.0147418839788015 GO:0048027 mRNA 5'-UTR binding 8/1553 24/18639 0.333333333333333 4.00064391500322 0.000498291106715652 0.023240297217218 GO:0035925 mRNA 3'-UTR AU-rich region binding 9/1553 30/18639 0.3 3.6005795235029 0.000539739302368961 0.0242052317908542 GO:0005346 purine ribonucleotide transmembrane transporter activity 7/1553 19/18639 0.368421052631579 4.42176432710882 0.000565162669292052 0.0244066545331309 GO:0004857 enzyme inhibitor activity 54/1553 416/18639 0.129807692307692 1.55794306305414 0.000738763787655445 0.0307642348716517 GO:0019843 rRNA binding 14/1553 65/18639 0.215384615384615 2.58503145277131 0.000781107645263043 0.031405914288852 GO:0004129 cytochrome-c oxidase activity 6/1553 15/18639 0.4 4.80077269800386 0.00085786414432853 0.0333423197429022 GO:1901505 carbohydrate derivative transmembrane transporter activity 12/1553 53/18639 0.226415094339623 2.71741850830407 0.00114526571664302 0.0422934175474517 GO:0044183 protein folding chaperone 15/1553 75/18639 0.2 2.40038634900193 0.00116071128775168 0.0422934175474517 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/1553 16/18639 0.375 4.50072440437862 0.00127634871053602 0.0450976544389393 GO:0017069 snRNA binding 12/1553 54/18639 0.222222222222222 2.66709594333548 0.00136263251794664 0.0467302798801701 GO:0051540 metal cluster binding 15/1553 77/18639 0.194805194805195 2.33803865162526 0.0015347288101251 0.0491424067644936 GO:0005201 extracellular matrix structural constituent 26/1553 168/18639 0.154761904761905 1.85744181768007 0.00154219321633618 0.0491424067644936 GO:0045499 chemorepellent activity 8/1553 28/18639 0.285714285714286 3.42912335571705 0.00155940741877038 0.0491424067644936 GO:0008307 structural constituent of muscle 10/1553 42/18639 0.238095238095238 2.85760279643087 0.00194209337754543 0.0581653931922057 GO:0043236 laminin binding 8/1553 29/18639 0.275862068965517 3.31087772276128 0.00199815307033566 0.0581653931922057 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 21/1553 128/18639 0.1640625 1.96906692691565 0.00203087347630703 0.0581653931922057 GO:0000295 adenine nucleotide transmembrane transporter activity 7/1553 23/18639 0.304347826086957 3.65276183543772 0.00204526682751324 0.0581653931922057 GO:0008201 heparin binding 26/1553 172/18639 0.151162790697674 1.81424549633867 0.00216618535062258 0.0599919509665822 GO:0005518 collagen binding 14/1553 72/18639 0.194444444444444 2.33370895041854 0.00221239613341598 0.0599919509665822 GO:0022804 active transmembrane transporter activity 56/1553 457/18639 0.12253829321663 1.47069623133598 0.00227817266648739 0.0601833197058796 GO:0015605 organophosphate ester transmembrane transporter activity 11/1553 50/18639 0.22 2.64042498390212 0.00232268386514973 0.0601833197058796 GO:0140297 DNA-binding transcription factor binding 59/1553 488/18639 0.120901639344262 1.45105322326961 0.00240806754553657 0.0610392773499052 GO:0030215 semaphorin receptor binding 7/1553 24/18639 0.291666666666667 3.50056342562782 0.00268225683019459 0.0665427971065297 GO:0045296 cadherin binding 43/1553 334/18639 0.12874251497006 1.54515887735154 0.00283444472893837 0.0688533865404612 GO:0050145 nucleoside monophosphate kinase activity 6/1553 19/18639 0.315789473684211 3.79008370895042 0.00347996489073832 0.0828089604612424 GO:0051087 protein-folding chaperone binding 21/1553 134/18639 0.156716417910448 1.8808997510836 0.00357626389553649 0.0833984740439109 GO:0051536 iron-sulfur cluster binding 14/1553 76/18639 0.184210526315789 2.21088216355441 0.00372436140765044 0.0835116423330849 GO:0098631 cell adhesion mediator activity 14/1553 76/18639 0.184210526315789 2.21088216355441 0.00372436140765044 0.0835116423330849 GO:0019955 cytokine binding 22/1553 144/18639 0.152777777777778 1.83362846104314 0.00399558946799832 0.087902968295963 GO:0015216 purine nucleotide transmembrane transporter activity 7/1553 26/18639 0.269230769230769 3.23128931596414 0.0044006455749427 0.0950213470441331 GO:0098632 cell-cell adhesion mediator activity 11/1553 55/18639 0.2 2.40038634900193 0.00507156156425621 0.107517105162232 GO:0043021 ribonucleoprotein complex binding 25/1553 177/18639 0.141242937853107 1.69518809957764 0.00639403549356296 0.1331329533124 GO:0030957 Tat protein binding 4/1553 10/18639 0.4 4.80077269800386 0.00669498666793429 0.13494141043605 GO:0015932 nucleobase-containing compound transmembrane transporter activity 11/1553 57/18639 0.192982456140351 2.31616226658081 0.00671235146251364 0.13494141043605 GO:0005178 integrin binding 23/1553 161/18639 0.142857142857143 1.71456167785852 0.00756806999647474 0.149565586709992 GO:0017070 U6 snRNA binding 5/1553 16/18639 0.3125 3.75060367031552 0.00799097633802859 0.155291306835689 GO:0019838 growth factor binding 20/1553 136/18639 0.147058823529412 1.76498996250142 0.00894897960873723 0.171057544652256 GO:0005114 type II transforming growth factor beta receptor binding 4/1553 11/18639 0.363636363636364 4.36433881636715 0.00983383221669416 0.179160130697897 GO:0048185 activin binding 4/1553 11/18639 0.363636363636364 4.36433881636715 0.00983383221669416 0.179160130697897 GO:0070990 snRNP binding 4/1553 11/18639 0.363636363636364 4.36433881636715 0.00983383221669416 0.179160130697897 GO:0001968 fibronectin binding 7/1553 30/18639 0.233333333333333 2.80045074050225 0.0101635520124878 0.179556085553951 GO:0015215 nucleotide transmembrane transporter activity 7/1553 30/18639 0.233333333333333 2.80045074050225 0.0101635520124878 0.179556085553951 GO:0005092 GDP-dissociation inhibitor activity 5/1553 17/18639 0.294117647058824 3.52997992500284 0.0105561794636313 0.181007430214618 GO:0038191 neuropilin binding 5/1553 17/18639 0.294117647058824 3.52997992500284 0.0105561794636313 0.181007430214618 GO:0005539 glycosaminoglycan binding 31/1553 242/18639 0.128099173553719 1.53743753758388 0.0108484287176611 0.183322722968013 GO:0003779 actin binding 51/1553 443/18639 0.115124153498871 1.38171223249547 0.0114727052678152 0.191102490603894 GO:0030291 protein serine/threonine kinase inhibitor activity 9/1553 46/18639 0.195652173913043 2.34820403706711 0.0124389596307912 0.204279252528206 GO:0016776 phosphotransferase activity, phosphate group as acceptor 8/1553 39/18639 0.205128205128205 2.46193471692506 0.0136252203908489 0.220652874662914 GO:0140416 transcription regulator inhibitor activity 7/1553 33/18639 0.212121212121212 2.5458643095475 0.0171469455649474 0.273881349708612 GO:0005160 transforming growth factor beta receptor binding 6/1553 26/18639 0.230769230769231 2.76967655654069 0.0178764888099678 0.281675485843547 GO:0042056 chemoattractant activity 8/1553 42/18639 0.19047619047619 2.2860822371447 0.0209612954207096 0.318069196938293 GO:0004860 protein kinase inhibitor activity 13/1553 84/18639 0.154761904761905 1.85744181768007 0.021257036701612 0.318069196938293 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 6/1553 27/18639 0.222222222222222 2.66709594333548 0.0214067209925274 0.318069196938293 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 5/1553 20/18639 0.25 3.00048293625241 0.0214681928437816 0.318069196938293 GO:1901681 sulfur compound binding 33/1553 275/18639 0.12 1.44023180940116 0.0215501428457334 0.318069196938293 GO:0005347 ATP transmembrane transporter activity 4/1553 14/18639 0.285714285714286 3.42912335571705 0.024393643399491 0.340819652661134 GO:0008191 metalloendopeptidase inhibitor activity 4/1553 14/18639 0.285714285714286 3.42912335571705 0.024393643399491 0.340819652661134 GO:0032036 myosin heavy chain binding 4/1553 14/18639 0.285714285714286 3.42912335571705 0.024393643399491 0.340819652661134 GO:1990825 sequence-specific mRNA binding 4/1553 14/18639 0.285714285714286 3.42912335571705 0.024393643399491 0.340819652661134 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 40/1553 349/18639 0.114613180515759 1.37557956962861 0.0245530453032035 0.340819652661134 GO:0051019 mitogen-activated protein kinase binding 6/1553 28/18639 0.214285714285714 2.57184251678778 0.0253791633300107 0.348142405209324 GO:0016853 isomerase activity 23/1553 180/18639 0.127777777777778 1.5335801674179 0.0261632198165057 0.35472458495402 GO:0055106 ubiquitin-protein transferase regulator activity 7/1553 36/18639 0.194444444444444 2.33370895041854 0.0269694063065233 0.358472264963405 GO:0003924 GTPase activity 38/1553 331/18639 0.114803625377644 1.37786527586214 0.0272156193667338 0.358472264963405 GO:0019199 transmembrane receptor protein kinase activity 12/1553 78/18639 0.153846153846154 1.84645103769379 0.0273619481833131 0.358472264963405 GO:0008009 chemokine activity 8/1553 45/18639 0.177777777777778 2.13367675466838 0.0307297312465131 0.393953866211992 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/1553 15/18639 0.266666666666667 3.20051513200258 0.0311212754704197 0.393953866211992 GO:0034062 5'-3' RNA polymerase activity 5/1553 22/18639 0.227272727272727 2.72771176022947 0.0317595741200062 0.393953866211992 GO:0070034 telomerase RNA binding 5/1553 22/18639 0.227272727272727 2.72771176022947 0.0317595741200062 0.393953866211992 GO:0097747 RNA polymerase activity 5/1553 22/18639 0.227272727272727 2.72771176022947 0.0317595741200062 0.393953866211992 GO:0061135 endopeptidase regulator activity 23/1553 184/18639 0.125 1.50024146812621 0.0327040367684726 0.394504216595273 GO:0008236 serine-type peptidase activity 24/1553 194/18639 0.123711340206186 1.48477506123831 0.0329765996212567 0.394504216595273 GO:0003925 G protein activity 9/1553 54/18639 0.166666666666667 2.00032195750161 0.0331469535241568 0.394504216595273 GO:0003714 transcription corepressor activity 25/1553 204/18639 0.122549019607843 1.47082496875118 0.0331573012232734 0.394504216595273 GO:0019887 protein kinase regulator activity 30/1553 255/18639 0.117647058823529 1.41199197000114 0.034555291194997 0.399752819142068 GO:0019001 guanyl nucleotide binding 44/1553 400/18639 0.11 1.32021249195106 0.0352456940260536 0.399752819142068 GO:0032561 guanyl ribonucleotide binding 44/1553 400/18639 0.11 1.32021249195106 0.0352456940260536 0.399752819142068 GO:0005109 frizzled binding 7/1553 38/18639 0.184210526315789 2.21088216355441 0.035305303080578 0.399752819142068 GO:0019210 kinase inhibitor activity 13/1553 90/18639 0.144444444444444 1.73361236316806 0.0353126418281586 0.399752819142068 GO:0005504 fatty acid binding 8/1553 47/18639 0.170212765957447 2.04288199915058 0.0387448504206615 0.415388839094482 GO:0005024 transforming growth factor beta receptor activity 4/1553 16/18639 0.25 3.00048293625241 0.0388313751812166 0.415388839094482 GO:0005159 insulin-like growth factor receptor binding 4/1553 16/18639 0.25 3.00048293625241 0.0388313751812166 0.415388839094482 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 4/1553 16/18639 0.25 3.00048293625241 0.0388313751812166 0.415388839094482 GO:0043023 ribosomal large subunit binding 4/1553 16/18639 0.25 3.00048293625241 0.0388313751812166 0.415388839094482 GO:0070411 I-SMAD binding 4/1553 16/18639 0.25 3.00048293625241 0.0388313751812166 0.415388839094482 GO:0017171 serine hydrolase activity 24/1553 198/18639 0.121212121212121 1.45477960545572 0.0404941074297023 0.429237538754845 GO:0005345 purine nucleobase transmembrane transporter activity 3/1553 10/18639 0.3 3.6005795235029 0.0444198600407393 0.4430595752636 GO:0008239 dipeptidyl-peptidase activity 3/1553 10/18639 0.3 3.6005795235029 0.0444198600407393 0.4430595752636 GO:0016783 sulfurtransferase activity 3/1553 10/18639 0.3 3.6005795235029 0.0444198600407393 0.4430595752636 GO:0070097 delta-catenin binding 3/1553 10/18639 0.3 3.6005795235029 0.0444198600407393 0.4430595752636 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 3/1553 10/18639 0.3 3.6005795235029 0.0444198600407393 0.4430595752636 GO:0031072 heat shock protein binding 17/1553 131/18639 0.129770992366412 1.55750259286385 0.0446597337525513 0.4430595752636 GO:0050431 transforming growth factor beta binding 5/1553 24/18639 0.208333333333333 2.50040244687701 0.0446819258185526 0.4430595752636 GO:0043022 ribosome binding 15/1553 112/18639 0.133928571428571 1.60740157299236 0.0450647400984038 0.4430595752636 GO:0051117 ATPase binding 12/1553 84/18639 0.142857142857143 1.71456167785852 0.0452179154857362 0.4430595752636 GO:0030515 snoRNA binding 6/1553 32/18639 0.1875 2.25036220218931 0.0460389305649776 0.443373229429969 GO:0004550 nucleoside diphosphate kinase activity 4/1553 17/18639 0.235294117647059 2.82398394000227 0.0475314354020122 0.443373229429969 GO:0004659 prenyltransferase activity 4/1553 17/18639 0.235294117647059 2.82398394000227 0.0475314354020122 0.443373229429969 GO:0008429 phosphatidylethanolamine binding 4/1553 17/18639 0.235294117647059 2.82398394000227 0.0475314354020122 0.443373229429969 GO:0032977 membrane insertase activity 4/1553 17/18639 0.235294117647059 2.82398394000227 0.0475314354020122 0.443373229429969 GO:0070492 oligosaccharide binding 4/1553 17/18639 0.235294117647059 2.82398394000227 0.0475314354020122 0.443373229429969 GO:0005525 GTP binding 41/1553 378/18639 0.108465608465608 1.30179682948517 0.0491848588462622 0.446108649823772 GO:0001530 lipopolysaccharide binding 7/1553 41/18639 0.170731707317073 2.04911029792848 0.0507300144347317 0.446108649823772 GO:0019211 phosphatase activator activity 5/1553 25/18639 0.2 2.40038634900193 0.0521607375650272 0.446108649823772 GO:0120020 cholesterol transfer activity 5/1553 25/18639 0.2 2.40038634900193 0.0521607375650272 0.446108649823772 GO:0019956 chemokine binding 6/1553 33/18639 0.181818181818182 2.18216940818357 0.0524593716760953 0.446108649823772 GO:0016209 antioxidant activity 12/1553 86/18639 0.13953488372093 1.67468815046646 0.05263354392727 0.446108649823772 GO:0048020 CCR chemokine receptor binding 8/1553 50/18639 0.16 1.92030907920155 0.053199270121085 0.446108649823772 GO:0070888 E-box binding 9/1553 59/18639 0.152542372881356 1.83080314754385 0.0542167459903174 0.446108649823772 GO:0001221 transcription coregulator binding 15/1553 115/18639 0.130434782608696 1.56546935804474 0.054692828593953 0.446108649823772 GO:0019207 kinase regulator activity 32/1553 287/18639 0.111498257839721 1.33819448027982 0.0556625740801227 0.446108649823772 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 4/1553 18/18639 0.222222222222222 2.66709594333548 0.0572170383698686 0.446108649823772 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 4/1553 18/18639 0.222222222222222 2.66709594333548 0.0572170383698686 0.446108649823772 GO:0070628 proteasome binding 4/1553 18/18639 0.222222222222222 2.66709594333548 0.0572170383698686 0.446108649823772 GO:0098641 cadherin binding involved in cell-cell adhesion 4/1553 18/18639 0.222222222222222 2.66709594333548 0.0572170383698686 0.446108649823772 GO:0003953 NAD+ nucleosidase activity 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0010854 adenylate cyclase regulator activity 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0015205 nucleobase transmembrane transporter activity 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0015217 ADP transmembrane transporter activity 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0032794 GTPase activating protein binding 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0034511 U3 snoRNA binding 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0050998 nitric-oxide synthase binding 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0097493 structural molecule activity conferring elasticity 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:1990948 ubiquitin ligase inhibitor activity 3/1553 11/18639 0.272727272727273 3.27325411227536 0.0573896204747562 0.446108649823772 GO:0061134 peptidase regulator activity 26/1553 226/18639 0.115044247787611 1.38075320960288 0.0580487362222632 0.448243883676549 GO:0033218 amide binding 28/1553 247/18639 0.11336032388664 1.36054286987964 0.0590642763465649 0.453085172500623 GO:0044325 transmembrane transporter binding 17/1553 136/18639 0.125 1.50024146812621 0.0598488354122892 0.45610288948189 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 9/1553 61/18639 0.147540983606557 1.77077681483749 0.0646375418182513 0.489398530909617 GO:0048306 calcium-dependent protein binding 11/1553 80/18639 0.1375 1.65026561493883 0.0673017497148124 0.50407530265122 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/1553 19/18639 0.210526315789474 2.52672247263361 0.0678729181099842 0.50407530265122 GO:0005520 insulin-like growth factor binding 4/1553 19/18639 0.210526315789474 2.52672247263361 0.0678729181099842 0.50407530265122 GO:0019205 nucleobase-containing compound kinase activity 7/1553 44/18639 0.159090909090909 1.90939823216063 0.0698383823803617 0.513739775515599 GO:0030414 peptidase inhibitor activity 20/1553 169/18639 0.118343195266272 1.42034695207215 0.0700554239339453 0.513739775515599 GO:0015269 calcium-activated potassium channel activity 3/1553 12/18639 0.25 3.00048293625241 0.0719225413800454 0.524135520307081 GO:0015485 cholesterol binding 8/1553 54/18639 0.148148148148148 1.77806396222365 0.0772468752667955 0.557888506023967 GO:0004866 endopeptidase inhibitor activity 19/1553 161/18639 0.118012422360248 1.41637703823095 0.0775837839254063 0.557888506023967 GO:0051082 unfolded protein binding 15/1553 121/18639 0.12396694214876 1.48784277830698 0.0779895595899713 0.557888506023967 GO:0016004 phospholipase activator activity 4/1553 20/18639 0.2 2.40038634900193 0.0794740994265349 0.558233734526143 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/1553 20/18639 0.2 2.40038634900193 0.0794740994265349 0.558233734526143 GO:0043024 ribosomal small subunit binding 4/1553 20/18639 0.2 2.40038634900193 0.0794740994265349 0.558233734526143 GO:0004521 RNA endonuclease activity 10/1553 73/18639 0.136986301369863 1.64410023904242 0.0802013087623674 0.559968419262997 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 15/1553 122/18639 0.122950819672131 1.47564734569791 0.0824163158759634 0.572008478043889 GO:0140313 molecular sequestering activity 8/1553 55/18639 0.145454545454545 1.74573552654686 0.0841292287226898 0.580441897577848 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/1553 13/18639 0.230769230769231 2.76967655654069 0.0879108609355053 0.589103815234478 GO:0005172 vascular endothelial growth factor receptor binding 3/1553 13/18639 0.230769230769231 2.76967655654069 0.0879108609355053 0.589103815234478 GO:0005338 nucleotide-sugar transmembrane transporter activity 3/1553 13/18639 0.230769230769231 2.76967655654069 0.0879108609355053 0.589103815234478 GO:0019855 calcium channel inhibitor activity 3/1553 13/18639 0.230769230769231 2.76967655654069 0.0879108609355053 0.589103815234478 GO:0031994 insulin-like growth factor I binding 3/1553 13/18639 0.230769230769231 2.76967655654069 0.0879108609355053 0.589103815234478 GO:0004181 metallocarboxypeptidase activity 5/1553 29/18639 0.172413793103448 2.0692985767258 0.0888700250052779 0.592128280892309 GO:0072542 protein phosphatase activator activity 4/1553 21/18639 0.19047619047619 2.2860822371447 0.091987071000387 0.609414345377564 GO:0004252 serine-type endopeptidase activity 20/1553 176/18639 0.113636363636364 1.36385588011473 0.0963153418028887 0.634484116057447 GO:0019992 diacylglycerol binding 3/1553 14/18639 0.214285714285714 2.57184251678778 0.105233738445327 0.67137999138015 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 3/1553 14/18639 0.214285714285714 2.57184251678778 0.105233738445327 0.67137999138015 GO:0031404 chloride ion binding 3/1553 14/18639 0.214285714285714 2.57184251678778 0.105233738445327 0.67137999138015 GO:0044548 S100 protein binding 3/1553 14/18639 0.214285714285714 2.57184251678778 0.105233738445327 0.67137999138015 GO:0070742 C2H2 zinc finger domain binding 3/1553 14/18639 0.214285714285714 2.57184251678778 0.105233738445327 0.67137999138015 GO:0061133 endopeptidase activator activity 4/1553 22/18639 0.181818181818182 2.18216940818357 0.105370959196027 0.67137999138015 GO:0016922 nuclear receptor binding 16/1553 137/18639 0.116788321167883 1.4016854592712 0.105981558955155 0.671600531204951 GO:0042826 histone deacetylase binding 15/1553 127/18639 0.118110236220472 1.41755099350508 0.106937069739385 0.673992558465526 GO:0030331 nuclear estrogen receptor binding 6/1553 40/18639 0.15 1.80028976175145 0.111831287607978 0.701049899736033 GO:0031593 polyubiquitin modification-dependent protein binding 8/1553 59/18639 0.135593220338983 1.62738057559453 0.115111793588474 0.717755889434012 GO:0004022 alcohol dehydrogenase (NAD+) activity 4/1553 23/18639 0.173913043478261 2.08729247739298 0.119578676765736 0.721531609922186 GO:0017134 fibroblast growth factor binding 4/1553 23/18639 0.173913043478261 2.08729247739298 0.119578676765736 0.721531609922186 GO:0033293 monocarboxylic acid binding 10/1553 79/18639 0.126582278481013 1.51923186645692 0.119898324820094 0.721531609922186 GO:0061650 ubiquitin-like protein conjugating enzyme activity 6/1553 41/18639 0.146341463414634 1.75638025536727 0.122305791580534 0.721531609922186 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/1553 32/18639 0.15625 1.87530183515776 0.123212798623484 0.721531609922186 GO:0071813 lipoprotein particle binding 5/1553 32/18639 0.15625 1.87530183515776 0.123212798623484 0.721531609922186 GO:0071814 protein-lipid complex binding 5/1553 32/18639 0.15625 1.87530183515776 0.123212798623484 0.721531609922186 GO:0120015 sterol transfer activity 5/1553 32/18639 0.15625 1.87530183515776 0.123212798623484 0.721531609922186 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/1553 60/18639 0.133333333333333 1.60025756600129 0.123701237455614 0.721531609922186 GO:0000774 adenyl-nucleotide exchange factor activity 3/1553 15/18639 0.2 2.40038634900193 0.123761854189054 0.721531609922186 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/1553 15/18639 0.2 2.40038634900193 0.123761854189054 0.721531609922186 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 3/1553 15/18639 0.2 2.40038634900193 0.123761854189054 0.721531609922186 GO:0140161 monocarboxylate:sodium symporter activity 3/1553 15/18639 0.2 2.40038634900193 0.123761854189054 0.721531609922186 GO:0005315 phosphate transmembrane transporter activity 4/1553 24/18639 0.166666666666667 2.00032195750161 0.134558026955173 0.741375186297191 GO:0019957 C-C chemokine binding 4/1553 24/18639 0.166666666666667 2.00032195750161 0.134558026955173 0.741375186297191 GO:0060229 lipase activator activity 4/1553 24/18639 0.166666666666667 2.00032195750161 0.134558026955173 0.741375186297191 GO:0001618 virus receptor activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0033192 calmodulin-dependent protein phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0140791 histone H2AXS140 phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/1553 81/18639 0.123456790123457 1.48171996851971 0.135174484630752 0.741375186297191 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 15/1553 132/18639 0.113636363636364 1.36385588011473 0.135431316193226 0.741375186297191 GO:0008238 exopeptidase activity 12/1553 102/18639 0.117647058823529 1.41199197000114 0.14120349743734 0.752969161942862 GO:0042379 chemokine receptor binding 9/1553 72/18639 0.125 1.50024146812621 0.143093214091543 0.752969161942862 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/1553 82/18639 0.121951219512195 1.46365021280606 0.143181068814208 0.752969161942862 GO:0033549 MAP kinase phosphatase activity 10/1553 82/18639 0.121951219512195 1.46365021280606 0.143181068814208 0.752969161942862 GO:0140272 exogenous protein binding 10/1553 82/18639 0.121951219512195 1.46365021280606 0.143181068814208 0.752969161942862 GO:0016722 oxidoreductase activity, acting on metal ions 3/1553 16/18639 0.1875 2.25036220218931 0.143361195498555 0.752969161942862 GO:0022858 alanine transmembrane transporter activity 3/1553 16/18639 0.1875 2.25036220218931 0.143361195498555 0.752969161942862 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/1553 16/18639 0.1875 2.25036220218931 0.143361195498555 0.752969161942862 GO:0097027 ubiquitin-protein transferase activator activity 3/1553 16/18639 0.1875 2.25036220218931 0.143361195498555 0.752969161942862 GO:0048156 tau protein binding 6/1553 43/18639 0.13953488372093 1.67468815046646 0.144625030656165 0.756200832937618 GO:0016860 intramolecular oxidoreductase activity 7/1553 53/18639 0.132075471698113 1.58516079651071 0.149257096769796 0.770256498837751 GO:0034212 protein N-acetyltransferase activity 7/1553 53/18639 0.132075471698113 1.58516079651071 0.149257096769796 0.770256498837751 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 4/1553 25/18639 0.16 1.92030907920155 0.150252748743772 0.770256498837751 GO:0003712 transcription coregulator activity 48/1553 495/18639 0.096969696969697 1.16382368436457 0.15132811024247 0.770256498837751 GO:0001540 amyloid-beta binding 10/1553 83/18639 0.120481927710843 1.44601587289273 0.151426947237208 0.770256498837751 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 10/1553 83/18639 0.120481927710843 1.44601587289273 0.151426947237208 0.770256498837751 GO:0043539 protein serine/threonine kinase activator activity 9/1553 73/18639 0.123287671232877 1.47969021513818 0.151937388278459 0.770256498837751 GO:0001046 core promoter sequence-specific DNA binding 6/1553 44/18639 0.136363636363636 1.63662705613768 0.156433448804977 0.776841073210257 GO:0030547 signaling receptor inhibitor activity 6/1553 44/18639 0.136363636363636 1.63662705613768 0.156433448804977 0.776841073210257 GO:0005126 cytokine receptor binding 28/1553 275/18639 0.101818181818182 1.2220148685828 0.156443038318928 0.776841073210257 GO:0042562 hormone binding 11/1553 94/18639 0.117021276595745 1.40448137441602 0.15813522140764 0.776841073210257 GO:0043177 organic acid binding 20/1553 189/18639 0.105820105820106 1.27004568730261 0.159851709612504 0.776841073210257 GO:0017018 myosin phosphatase activity 10/1553 84/18639 0.119047619047619 1.42880139821544 0.159906634551629 0.776841073210257 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/1553 54/18639 0.12962962962963 1.5558059669457 0.159982023376626 0.776841073210257 GO:0048029 monosaccharide binding 9/1553 74/18639 0.121621621621622 1.45969440142009 0.161044046362886 0.776841073210257 GO:0016229 steroid dehydrogenase activity 5/1553 35/18639 0.142857142857143 1.71456167785852 0.16272400570661 0.776841073210257 GO:0004549 tRNA-specific ribonuclease activity 3/1553 17/18639 0.176470588235294 2.1179879550017 0.163896144090672 0.776841073210257 GO:0016018 cyclosporin A binding 3/1553 17/18639 0.176470588235294 2.1179879550017 0.163896144090672 0.776841073210257 GO:0017110 nucleoside diphosphate phosphatase activity 3/1553 17/18639 0.176470588235294 2.1179879550017 0.163896144090672 0.776841073210257 GO:0030169 low-density lipoprotein particle binding 3/1553 17/18639 0.176470588235294 2.1179879550017 0.163896144090672 0.776841073210257 GO:0030548 acetylcholine receptor regulator activity 3/1553 17/18639 0.176470588235294 2.1179879550017 0.163896144090672 0.776841073210257 GO:0048038 quinone binding 3/1553 17/18639 0.176470588235294 2.1179879550017 0.163896144090672 0.776841073210257 GO:0051787 misfolded protein binding 3/1553 17/18639 0.176470588235294 2.1179879550017 0.163896144090672 0.776841073210257 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1553 26/18639 0.153846153846154 1.84645103769379 0.166603493254407 0.783305133607412 GO:0008198 ferrous iron binding 4/1553 26/18639 0.153846153846154 1.84645103769379 0.166603493254407 0.783305133607412 GO:0051539 4 iron, 4 sulfur cluster binding 6/1553 45/18639 0.133333333333333 1.60025756600129 0.16864742437663 0.789730509329922 GO:0016407 acetyltransferase activity 11/1553 96/18639 0.114583333333333 1.37522134578236 0.174623226295184 0.814442727440737 GO:0019208 phosphatase regulator activity 13/1553 117/18639 0.111111111111111 1.33354797166774 0.175585287949279 0.815667114537289 GO:0004190 aspartic-type endopeptidase activity 5/1553 36/18639 0.138888888888889 1.66693496458467 0.176900156775887 0.818514217463031 GO:0004180 carboxypeptidase activity 6/1553 46/18639 0.130434782608696 1.56546935804474 0.181244934152161 0.830719573588241 GO:0000400 four-way junction DNA binding 3/1553 18/18639 0.166666666666667 2.00032195750161 0.185231965234832 0.830719573588241 GO:0015172 acidic amino acid transmembrane transporter activity 3/1553 18/18639 0.166666666666667 2.00032195750161 0.185231965234832 0.830719573588241 GO:0099602 neurotransmitter receptor regulator activity 3/1553 18/18639 0.166666666666667 2.00032195750161 0.185231965234832 0.830719573588241 GO:1901611 phosphatidylglycerol binding 3/1553 18/18639 0.166666666666667 2.00032195750161 0.185231965234832 0.830719573588241 GO:0005496 steroid binding 12/1553 108/18639 0.111111111111111 1.33354797166774 0.18762275112551 0.830719573588241 GO:0042805 actinin binding 5/1553 37/18639 0.135135135135135 1.62188266824455 0.191521241469072 0.830719573588241 GO:0043394 proteoglycan binding 5/1553 37/18639 0.135135135135135 1.62188266824455 0.191521241469072 0.830719573588241 GO:0070001 aspartic-type peptidase activity 5/1553 37/18639 0.135135135135135 1.62188266824455 0.191521241469072 0.830719573588241 GO:0008083 growth factor activity 17/1553 162/18639 0.104938271604938 1.25946197324175 0.192520355551916 0.830719573588241 GO:0004601 peroxidase activity 7/1553 57/18639 0.12280701754386 1.47392144236961 0.194116147461037 0.830719573588241 GO:0016504 peptidase activator activity 7/1553 57/18639 0.12280701754386 1.47392144236961 0.194116147461037 0.830719573588241 GO:0061733 protein-lysine-acetyltransferase activity 6/1553 47/18639 0.127659574468085 1.53216149936294 0.194202746724097 0.830719573588241 GO:0004382 GDP phosphatase activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0005031 tumor necrosis factor receptor activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0005528 FK506 binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0031419 cobalamin binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0031434 mitogen-activated protein kinase kinase binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0031996 thioesterase binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0033204 ribonuclease P RNA binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0050815 phosphoserine residue binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0097177 mitochondrial ribosome binding 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0140940 histone H2A methyltransferase activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0141109 transporter activator activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:1990259 histone H2AQ104 methyltransferase activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:1990757 ubiquitin ligase activator activity 2/1553 10/18639 0.2 2.40038634900193 0.200199142519979 0.830719573588241 GO:0097718 disordered domain specific binding 4/1553 28/18639 0.142857142857143 1.71456167785852 0.201025543493376 0.831190722387504 GO:0032934 sterol binding 8/1553 68/18639 0.117647058823529 1.41199197000114 0.203387101976473 0.833234803936152 GO:0005501 retinoid binding 5/1553 38/18639 0.131578947368421 1.57920154539601 0.206550376816575 0.833234803936152 GO:0019840 isoprenoid binding 5/1553 38/18639 0.131578947368421 1.57920154539601 0.206550376816575 0.833234803936152 GO:0003756 protein disulfide isomerase activity 3/1553 19/18639 0.157894736842105 1.89504185447521 0.207236786570741 0.833234803936152 GO:0008301 DNA binding, bending 3/1553 19/18639 0.157894736842105 1.89504185447521 0.207236786570741 0.833234803936152 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/1553 19/18639 0.157894736842105 1.89504185447521 0.207236786570741 0.833234803936152 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/1553 19/18639 0.157894736842105 1.89504185447521 0.207236786570741 0.833234803936152 GO:0043395 heparan sulfate proteoglycan binding 3/1553 19/18639 0.157894736842105 1.89504185447521 0.207236786570741 0.833234803936152 GO:0043130 ubiquitin binding 11/1553 100/18639 0.11 1.32021249195106 0.209897650493922 0.841033197511729 GO:0031406 carboxylic acid binding 19/1553 187/18639 0.101604278074866 1.21944761045553 0.214399633611445 0.84958989886432 GO:0051015 actin filament binding 21/1553 209/18639 0.100478468899522 1.20593572557513 0.214523021871291 0.84958989886432 GO:0008080 N-acetyltransferase activity 8/1553 69/18639 0.115942028985507 1.39152831826199 0.214558704673526 0.84958989886432 GO:0004879 nuclear receptor activity 7/1553 59/18639 0.11864406779661 1.42395800364521 0.218340685601071 0.84958989886432 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/1553 59/18639 0.11864406779661 1.42395800364521 0.218340685601071 0.84958989886432 GO:0051861 glycolipid binding 4/1553 29/18639 0.137931034482759 1.65543886138064 0.218970426451472 0.84958989886432 GO:0001222 transcription corepressor binding 6/1553 49/18639 0.122448979591837 1.46962429530731 0.221101425677437 0.84958989886432 GO:0016763 pentosyltransferase activity 6/1553 49/18639 0.122448979591837 1.46962429530731 0.221101425677437 0.84958989886432 GO:0060590 ATPase regulator activity 6/1553 49/18639 0.122448979591837 1.46962429530731 0.221101425677437 0.84958989886432 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/1553 39/18639 0.128205128205128 1.53870919807816 0.221949754637939 0.84958989886432 GO:0097110 scaffold protein binding 8/1553 70/18639 0.114285714285714 1.37164934228682 0.225957215085997 0.84958989886432 GO:0001972 retinoic acid binding 3/1553 20/18639 0.15 1.80028976175145 0.229783143125601 0.84958989886432 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 3/1553 20/18639 0.15 1.80028976175145 0.229783143125601 0.84958989886432 GO:0010851 cyclase regulator activity 3/1553 20/18639 0.15 1.80028976175145 0.229783143125601 0.84958989886432 GO:0016505 peptidase activator activity involved in apoptotic process 3/1553 20/18639 0.15 1.80028976175145 0.229783143125601 0.84958989886432 GO:0098531 ligand-modulated transcription factor activity 7/1553 60/18639 0.116666666666667 1.40022537025113 0.230840235356131 0.84958989886432 GO:0000099 sulfur amino acid transmembrane transporter activity 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0008199 ferric iron binding 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0008432 JUN kinase binding 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0034713 type I transforming growth factor beta receptor binding 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0045294 alpha-catenin binding 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0050786 RAGE receptor binding 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0140031 phosphorylation-dependent protein binding 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0180030 inositol phosphate kinase activity 2/1553 11/18639 0.181818181818182 2.18216940818357 0.231934591863362 0.84958989886432 GO:0005125 cytokine activity 23/1553 234/18639 0.0982905982905983 1.17967705185992 0.232434972330805 0.84958989886432 GO:0043178 alcohol binding 10/1553 92/18639 0.108695652173913 1.30455779837062 0.235338914399739 0.857516169344049 GO:0001965 G-protein alpha-subunit binding 4/1553 30/18639 0.133333333333333 1.60025756600129 0.23731989075167 0.858006205179919 GO:0015036 disulfide oxidoreductase activity 5/1553 40/18639 0.125 1.50024146812621 0.237680964213648 0.858006205179919 GO:0140662 ATP-dependent protein folding chaperone 5/1553 40/18639 0.125 1.50024146812621 0.237680964213648 0.858006205179919 GO:0002020 protease binding 14/1553 136/18639 0.102941176470588 1.23549297375099 0.242350214127786 0.864467821026376 GO:0015026 coreceptor activity 7/1553 61/18639 0.114754098360656 1.37727085598472 0.243572940200785 0.864467821026376 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/1553 21/18639 0.142857142857143 1.71456167785852 0.25274915514647 0.864467821026376 GO:0008373 sialyltransferase activity 3/1553 21/18639 0.142857142857143 1.71456167785852 0.25274915514647 0.864467821026376 GO:0036122 BMP binding 3/1553 21/18639 0.142857142857143 1.71456167785852 0.25274915514647 0.864467821026376 GO:0140318 protein transporter activity 5/1553 41/18639 0.121951219512195 1.46365021280606 0.253705293746025 0.864467821026376 GO:0016410 N-acyltransferase activity 10/1553 94/18639 0.106382978723404 1.27680124946911 0.256008928992494 0.864467821026376 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/1553 31/18639 0.129032258064516 1.54863635419479 0.256011077272015 0.864467821026376 GO:0047499 calcium-independent phospholipase A2 activity 4/1553 31/18639 0.129032258064516 1.54863635419479 0.256011077272015 0.864467821026376 GO:0070325 lipoprotein particle receptor binding 4/1553 31/18639 0.129032258064516 1.54863635419479 0.256011077272015 0.864467821026376 GO:0072349 modified amino acid transmembrane transporter activity 4/1553 31/18639 0.129032258064516 1.54863635419479 0.256011077272015 0.864467821026376 GO:0042277 peptide binding 24/1553 249/18639 0.0963855421686747 1.15681269831418 0.25647730942361 0.864467821026376 GO:0004519 endonuclease activity 13/1553 127/18639 0.102362204724409 1.22854419437107 0.25932188573928 0.864467821026376 GO:0005080 protein kinase C binding 6/1553 52/18639 0.115384615384615 1.38483827827035 0.263521757988508 0.864467821026376 GO:0003995 acyl-CoA dehydrogenase activity 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0004300 enoyl-CoA hydratase activity 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0004526 ribonuclease P activity 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0005025 transforming growth factor beta receptor activity, type I 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0005026 transforming growth factor beta receptor activity, type II 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0005527 macrolide binding 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0008179 adenylate cyclase binding 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0016361 activin receptor activity, type I 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0016362 activin receptor activity, type II 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0017002 activin receptor activity 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0017166 vinculin binding 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0035259 nuclear glucocorticoid receptor binding 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0035497 cAMP response element binding 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0036009 protein-glutamine N-methyltransferase activity 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0042301 phosphate ion binding 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0070008 serine-type exopeptidase activity 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0097371 MDM2/MDM4 family protein binding 2/1553 12/18639 0.166666666666667 2.00032195750161 0.263937001960026 0.864467821026376 GO:0004867 serine-type endopeptidase inhibitor activity 10/1553 95/18639 0.105263157894737 1.26336123631681 0.266565437176768 0.870631091731406 GO:1901682 sulfur compound transmembrane transporter activity 7/1553 63/18639 0.111111111111111 1.33354797166774 0.269660331949009 0.871706414503105 GO:0031492 nucleosomal DNA binding 5/1553 42/18639 0.119047619047619 1.42880139821544 0.269984009503907 0.871706414503105 GO:0051879 Hsp90 protein binding 5/1553 42/18639 0.119047619047619 1.42880139821544 0.269984009503907 0.871706414503105 GO:0001664 G protein-coupled receptor binding 28/1553 297/18639 0.0942760942760943 1.13149524868778 0.273713275271906 0.871706414503105 GO:0043425 bHLH transcription factor binding 4/1553 32/18639 0.125 1.50024146812621 0.274982259936091 0.871706414503105 GO:0051059 NF-kappaB binding 4/1553 32/18639 0.125 1.50024146812621 0.274982259936091 0.871706414503105 GO:0008649 rRNA methyltransferase activity 3/1553 22/18639 0.136363636363636 1.63662705613768 0.276019396612329 0.871706414503105 GO:0015377 chloride:monoatomic cation symporter activity 3/1553 22/18639 0.136363636363636 1.63662705613768 0.276019396612329 0.871706414503105 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/1553 22/18639 0.136363636363636 1.63662705613768 0.276019396612329 0.871706414503105 GO:0140035 ubiquitin-like protein reader activity 3/1553 22/18639 0.136363636363636 1.63662705613768 0.276019396612329 0.871706414503105 GO:0004896 cytokine receptor activity 10/1553 96/18639 0.104166666666667 1.25020122343851 0.277256391930441 0.871706414503105 GO:0035591 signaling adaptor activity 13/1553 129/18639 0.10077519379845 1.20949699755911 0.27759296429328 0.871706414503105 GO:0019888 protein phosphatase regulator activity 11/1553 107/18639 0.102803738317757 1.23384345042155 0.277865978356621 0.871706414503105 GO:0005246 calcium channel regulator activity 6/1553 53/18639 0.113207547169811 1.35870925415204 0.278108736016428 0.871706414503105 GO:0017046 peptide hormone binding 6/1553 53/18639 0.113207547169811 1.35870925415204 0.278108736016428 0.871706414503105 GO:0050660 flavin adenine dinucleotide binding 9/1553 86/18639 0.104651162790698 1.25601611284985 0.287406652063659 0.88181843017966 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/1553 54/18639 0.111111111111111 1.33354797166774 0.292874575096403 0.88181843017966 GO:0050661 NADP binding 6/1553 54/18639 0.111111111111111 1.33354797166774 0.292874575096403 0.88181843017966 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/1553 33/18639 0.121212121212121 1.45477960545572 0.29417328349282 0.88181843017966 GO:0071889 14-3-3 protein binding 4/1553 33/18639 0.121212121212121 1.45477960545572 0.29417328349282 0.88181843017966 GO:0005035 death receptor activity 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0005542 folic acid binding 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0008035 high-density lipoprotein particle binding 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0039706 co-receptor binding 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0046975 histone H3K36 methyltransferase activity 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0070123 transforming growth factor beta receptor activity, type III 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1553 13/18639 0.153846153846154 1.84645103769379 0.295941754873576 0.88181843017966 GO:0120013 lipid transfer activity 7/1553 65/18639 0.107692307692308 1.29251572638566 0.296445492590114 0.88181843017966 GO:0017022 myosin binding 8/1553 76/18639 0.105263157894737 1.26336123631681 0.298295692507965 0.88181843017966 GO:0004602 glutathione peroxidase activity 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0005158 insulin receptor binding 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0005283 amino acid:sodium symporter activity 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0008171 O-methyltransferase activity 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0016849 phosphorus-oxygen lyase activity 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0031681 G-protein beta-subunit binding 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0042171 lysophosphatidic acid acyltransferase activity 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0071617 lysophospholipid acyltransferase activity 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0140102 catalytic activity, acting on a rRNA 3/1553 23/18639 0.130434782608696 1.56546935804474 0.299485504589319 0.88181843017966 GO:0004175 endopeptidase activity 37/1553 405/18639 0.091358024691358 1.09647277670459 0.301922516531883 0.885900115846513 GO:0001223 transcription coactivator binding 5/1553 44/18639 0.113636363636364 1.36385588011473 0.30315106880168 0.885900115846513 GO:0016790 thiolester hydrolase activity 5/1553 44/18639 0.113636363636364 1.36385588011473 0.30315106880168 0.885900115846513 GO:0005179 hormone activity 13/1553 132/18639 0.0984848484848485 1.18200842943277 0.305729920501093 0.891202718260686 GO:0004540 RNA nuclease activity 12/1553 121/18639 0.0991735537190083 1.19027422264559 0.30741277016611 0.893873541181257 GO:0015035 protein-disulfide reductase activity 4/1553 34/18639 0.117647058823529 1.41199197000114 0.31352593412637 0.907124663005826 GO:0030332 cyclin binding 4/1553 34/18639 0.117647058823529 1.41199197000114 0.31352593412637 0.907124663005826 GO:0019212 phosphatase inhibitor activity 6/1553 56/18639 0.107142857142857 1.28592125839389 0.322836450131554 0.916376524480766 GO:0035035 histone acetyltransferase binding 3/1553 24/18639 0.125 1.50024146812621 0.323046572822768 0.916376524480766 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/1553 24/18639 0.125 1.50024146812621 0.323046572822768 0.916376524480766 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/1553 24/18639 0.125 1.50024146812621 0.323046572822768 0.916376524480766 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/1553 24/18639 0.125 1.50024146812621 0.323046572822768 0.916376524480766 GO:0050699 WW domain binding 3/1553 24/18639 0.125 1.50024146812621 0.323046572822768 0.916376524480766 GO:0070300 phosphatidic acid binding 3/1553 24/18639 0.125 1.50024146812621 0.323046572822768 0.916376524480766 GO:0004705 JUN kinase activity 2/1553 14/18639 0.142857142857143 1.71456167785852 0.327726424278284 0.916376524480766 GO:0005161 platelet-derived growth factor receptor binding 2/1553 14/18639 0.142857142857143 1.71456167785852 0.327726424278284 0.916376524480766 GO:0042043 neurexin family protein binding 2/1553 14/18639 0.142857142857143 1.71456167785852 0.327726424278284 0.916376524480766 GO:0043176 amine binding 2/1553 14/18639 0.142857142857143 1.71456167785852 0.327726424278284 0.916376524480766 GO:0071933 Arp2/3 complex binding 2/1553 14/18639 0.142857142857143 1.71456167785852 0.327726424278284 0.916376524480766 GO:0098821 BMP receptor activity 2/1553 14/18639 0.142857142857143 1.71456167785852 0.327726424278284 0.916376524480766 GO:1901612 cardiolipin binding 2/1553 14/18639 0.142857142857143 1.71456167785852 0.327726424278284 0.916376524480766 GO:0005200 structural constituent of cytoskeleton 11/1553 112/18639 0.0982142857142857 1.17876115352773 0.330005133392156 0.920046522632743 GO:0004623 phospholipase A2 activity 4/1553 35/18639 0.114285714285714 1.37164934228682 0.332984247470855 0.920046522632743 GO:0005343 organic acid:sodium symporter activity 4/1553 35/18639 0.114285714285714 1.37164934228682 0.332984247470855 0.920046522632743 GO:0043015 gamma-tubulin binding 4/1553 35/18639 0.114285714285714 1.37164934228682 0.332984247470855 0.920046522632743 GO:0061631 ubiquitin conjugating enzyme activity 4/1553 35/18639 0.114285714285714 1.37164934228682 0.332984247470855 0.920046522632743 GO:0016835 carbon-oxygen lyase activity 8/1553 79/18639 0.10126582278481 1.21538549316554 0.336316173215397 0.924869476342341 GO:0046332 SMAD binding 8/1553 79/18639 0.10126582278481 1.21538549316554 0.336316173215397 0.924869476342341 GO:0005537 D-mannose binding 3/1553 25/18639 0.12 1.44023180940116 0.34660936701536 0.944267574625956 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/1553 25/18639 0.12 1.44023180940116 0.34660936701536 0.944267574625956 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/1553 25/18639 0.12 1.44023180940116 0.34660936701536 0.944267574625956 GO:0019707 protein-cysteine S-acyltransferase activity 3/1553 25/18639 0.12 1.44023180940116 0.34660936701536 0.944267574625956 GO:0005484 SNAP receptor activity 4/1553 36/18639 0.111111111111111 1.33354797166774 0.352494758807727 0.946736332927173 GO:0016409 palmitoyltransferase activity 4/1553 36/18639 0.111111111111111 1.33354797166774 0.352494758807727 0.946736332927173 GO:0045505 dynein intermediate chain binding 4/1553 36/18639 0.111111111111111 1.33354797166774 0.352494758807727 0.946736332927173 GO:0004722 protein serine/threonine phosphatase activity 10/1553 103/18639 0.0970873786407767 1.16523609174851 0.354993760321944 0.946736332927173 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 21/1553 229/18639 0.091703056768559 1.10061382814499 0.355615494911382 0.946736332927173 GO:0004089 carbonate dehydratase activity 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0005523 tropomyosin binding 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0016846 carbon-sulfur lyase activity 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0017081 chloride channel regulator activity 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0033130 acetylcholine receptor binding 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0051371 muscle alpha-actinin binding 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0140776 protein-containing complex destabilizing activity 2/1553 15/18639 0.133333333333333 1.60025756600129 0.359105588907396 0.946736332927173 GO:0008509 monoatomic anion transmembrane transporter activity 14/1553 149/18639 0.0939597315436242 1.12769828476601 0.359694850331679 0.946736332927173 GO:0001786 phosphatidylserine binding 6/1553 59/18639 0.101694915254237 1.2205354316959 0.368464560487316 0.958940149858332 GO:0015459 potassium channel regulator activity 6/1553 59/18639 0.101694915254237 1.2205354316959 0.368464560487316 0.958940149858332 GO:0005112 Notch binding 3/1553 26/18639 0.115384615384615 1.38483827827035 0.370088394027658 0.958940149858332 GO:0005227 calcium-activated cation channel activity 3/1553 26/18639 0.115384615384615 1.38483827827035 0.370088394027658 0.958940149858332 GO:0008157 protein phosphatase 1 binding 3/1553 26/18639 0.115384615384615 1.38483827827035 0.370088394027658 0.958940149858332 GO:0050681 nuclear androgen receptor binding 3/1553 26/18639 0.115384615384615 1.38483827827035 0.370088394027658 0.958940149858332 GO:0070412 R-SMAD binding 3/1553 26/18639 0.115384615384615 1.38483827827035 0.370088394027658 0.958940149858332 GO:0023023 MHC protein complex binding 4/1553 37/18639 0.108108108108108 1.29750613459564 0.372006700303322 0.959645602994854 GO:0030551 cyclic nucleotide binding 4/1553 37/18639 0.108108108108108 1.29750613459564 0.372006700303322 0.959645602994854 GO:0030295 protein kinase activator activity 13/1553 139/18639 0.0935251798561151 1.12248282507285 0.373877090486534 0.962341473526045 GO:0031490 chromatin DNA binding 12/1553 128/18639 0.09375 1.12518110109466 0.378779069231036 0.972811442122 GO:0008013 beta-catenin binding 10/1553 106/18639 0.0943396226415094 1.13225771179336 0.389290272319205 0.988378192353066 GO:0004707 MAP kinase activity 2/1553 16/18639 0.125 1.50024146812621 0.38992621653723 0.988378192353066 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1553 16/18639 0.125 1.50024146812621 0.38992621653723 0.988378192353066 GO:0015378 sodium:chloride symporter activity 2/1553 16/18639 0.125 1.50024146812621 0.38992621653723 0.988378192353066 GO:0019841 retinol binding 2/1553 16/18639 0.125 1.50024146812621 0.38992621653723 0.988378192353066 GO:0055102 lipase inhibitor activity 2/1553 16/18639 0.125 1.50024146812621 0.38992621653723 0.988378192353066 GO:0042887 amide transmembrane transporter activity 4/1553 38/18639 0.105263157894737 1.26336123631681 0.391472150125292 0.990144310295208 GO:0005044 scavenger receptor activity 3/1553 27/18639 0.111111111111111 1.33354797166774 0.393405852671441 0.990736985345358 GO:0023026 MHC class II protein complex binding 3/1553 27/18639 0.111111111111111 1.33354797166774 0.393405852671441 0.990736985345358 GO:0016836 hydro-lyase activity 6/1553 61/18639 0.0983606557377049 1.18051787655833 0.399048866201407 0.999999999859342 GO:0015103 inorganic anion transmembrane transporter activity 15/1553 165/18639 0.0909090909090909 1.09108470409179 0.401432552787339 0.999999999859342 GO:0016829 lyase activity 18/1553 200/18639 0.09 1.08017385705087 0.401936878301691 0.999999999859342 GO:0005006 epidermal growth factor receptor activity 5/1553 50/18639 0.1 1.20019317450097 0.404897892345119 0.999999999859342 GO:0005017 platelet-derived growth factor receptor activity 5/1553 50/18639 0.1 1.20019317450097 0.404897892345119 0.999999999859342 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1553 50/18639 0.1 1.20019317450097 0.404897892345119 0.999999999859342 GO:0019902 phosphatase binding 17/1553 190/18639 0.0894736842105263 1.07385705086929 0.416309540064421 0.999999999859342 GO:0005242 inward rectifier potassium channel activity 3/1553 28/18639 0.107142857142857 1.28592125839389 0.416491489772809 0.999999999859342 GO:0051393 alpha-actinin binding 3/1553 28/18639 0.107142857142857 1.28592125839389 0.416491489772809 0.999999999859342 GO:0032182 ubiquitin-like protein binding 11/1553 120/18639 0.0916666666666667 1.10017707662589 0.416634722648121 0.999999999859342 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1553 17/18639 0.117647058823529 1.41199197000114 0.420063559530104 0.999999999859342 GO:0015278 intracellularly gated calcium channel activity 2/1553 17/18639 0.117647058823529 1.41199197000114 0.420063559530104 0.999999999859342 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/1553 17/18639 0.117647058823529 1.41199197000114 0.420063559530104 0.999999999859342 GO:0046965 nuclear retinoid X receptor binding 2/1553 17/18639 0.117647058823529 1.41199197000114 0.420063559530104 0.999999999859342 GO:1990226 histone methyltransferase binding 2/1553 17/18639 0.117647058823529 1.41199197000114 0.420063559530104 0.999999999859342 GO:0005021 vascular endothelial growth factor receptor activity 5/1553 51/18639 0.0980392156862745 1.17665997500095 0.421828053312912 0.999999999859342 GO:0005048 signal sequence binding 5/1553 51/18639 0.0980392156862745 1.17665997500095 0.421828053312912 0.999999999859342 GO:0030544 Hsp70 protein binding 5/1553 51/18639 0.0980392156862745 1.17665997500095 0.421828053312912 0.999999999859342 GO:0019903 protein phosphatase binding 13/1553 144/18639 0.0902777777777778 1.08350772698004 0.423691818305277 0.999999999859342 GO:0003697 single-stranded DNA binding 11/1553 121/18639 0.0909090909090909 1.09108470409179 0.427556917896323 0.999999999859342 GO:0015108 chloride transmembrane transporter activity 11/1553 121/18639 0.0909090909090909 1.09108470409179 0.427556917896323 0.999999999859342 GO:0071949 FAD binding 4/1553 40/18639 0.1 1.20019317450097 0.43008671306625 0.999999999859342 GO:0003725 double-stranded RNA binding 7/1553 75/18639 0.0933333333333333 1.1201802962009 0.435351375621586 0.999999999859342 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 5/1553 52/18639 0.0961538461538462 1.15403189855862 0.438669148560189 0.999999999859342 GO:0030159 signaling receptor complex adaptor activity 5/1553 52/18639 0.0961538461538462 1.15403189855862 0.438669148560189 0.999999999859342 GO:0003785 actin monomer binding 3/1553 29/18639 0.103448275862069 1.24157914603548 0.439282381694501 0.999999999859342 GO:0005416 amino acid:monoatomic cation symporter activity 3/1553 29/18639 0.103448275862069 1.24157914603548 0.439282381694501 0.999999999859342 GO:0016417 S-acyltransferase activity 3/1553 29/18639 0.103448275862069 1.24157914603548 0.439282381694501 0.999999999859342 GO:0141108 transporter regulator activity 15/1553 170/18639 0.0882352941176471 1.05899397750085 0.447729229182638 0.999999999859342 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1553 41/18639 0.0975609756097561 1.17092017024484 0.449154974614382 0.999999999859342 GO:0017080 sodium channel regulator activity 4/1553 41/18639 0.0975609756097561 1.17092017024484 0.449154974614382 0.999999999859342 GO:0042287 MHC protein binding 4/1553 41/18639 0.0975609756097561 1.17092017024484 0.449154974614382 0.999999999859342 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0003746 translation elongation factor activity 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0015373 monoatomic anion:sodium symporter activity 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0016854 racemase and epimerase activity 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0032393 MHC class I receptor activity 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0050811 GABA receptor binding 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0070064 proline-rich region binding 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:1990381 ubiquitin-specific protease binding 2/1553 18/18639 0.111111111111111 1.33354797166774 0.449417508817013 0.999999999859342 GO:0004864 protein phosphatase inhibitor activity 5/1553 53/18639 0.0943396226415094 1.13225771179336 0.455394191533497 0.999999999859342 GO:0005003 ephrin receptor activity 5/1553 53/18639 0.0943396226415094 1.13225771179336 0.455394191533497 0.999999999859342 GO:0005005 transmembrane-ephrin receptor activity 5/1553 53/18639 0.0943396226415094 1.13225771179336 0.455394191533497 0.999999999859342 GO:0016251 RNA polymerase II general transcription initiation factor activity 5/1553 53/18639 0.0943396226415094 1.13225771179336 0.455394191533497 0.999999999859342 GO:0022839 monoatomic ion-gated channel activity 3/1553 30/18639 0.1 1.20019317450097 0.461722658465927 0.999999999859342 GO:0031210 phosphatidylcholine binding 3/1553 30/18639 0.1 1.20019317450097 0.461722658465927 0.999999999859342 GO:0048019 receptor antagonist activity 3/1553 30/18639 0.1 1.20019317450097 0.461722658465927 0.999999999859342 GO:0019209 kinase activator activity 13/1553 148/18639 0.0878378378378378 1.05422373435896 0.463597570645512 0.999999999859342 GO:0099106 ion channel regulator activity 14/1553 160/18639 0.0875 1.05016902768835 0.46498176127176 0.999999999859342 GO:0004402 histone acetyltransferase activity 4/1553 42/18639 0.0952380952380952 1.14304111857235 0.468015076204959 0.999999999859342 GO:0051287 NAD binding 5/1553 54/18639 0.0925925925925926 1.11128997638978 0.471977825863813 0.999999999859342 GO:0003713 transcription coactivator activity 22/1553 256/18639 0.0859375 1.03141600933677 0.472263674098623 0.999999999859342 GO:0008235 metalloexopeptidase activity 6/1553 66/18639 0.0909090909090909 1.09108470409179 0.474761235670498 0.999999999859342 GO:0015245 fatty acid transmembrane transporter activity 2/1553 19/18639 0.105263157894737 1.26336123631681 0.477909358493045 0.999999999859342 GO:0016918 retinal binding 2/1553 19/18639 0.105263157894737 1.26336123631681 0.477909358493045 0.999999999859342 GO:0034987 immunoglobulin receptor binding 2/1553 19/18639 0.105263157894737 1.26336123631681 0.477909358493045 0.999999999859342 GO:0042800 histone H3K4 methyltransferase activity 2/1553 19/18639 0.105263157894737 1.26336123631681 0.477909358493045 0.999999999859342 GO:0070003 threonine-type peptidase activity 2/1553 19/18639 0.105263157894737 1.26336123631681 0.477909358493045 0.999999999859342 GO:0140036 ubiquitin-modified protein reader activity 2/1553 19/18639 0.105263157894737 1.26336123631681 0.477909358493045 0.999999999859342 GO:1990380 K48-linked deubiquitinase activity 2/1553 19/18639 0.105263157894737 1.26336123631681 0.477909358493045 0.999999999859342 GO:0008514 organic anion transmembrane transporter activity 23/1553 269/18639 0.0855018587360595 1.02618747262164 0.480288095177349 0.999999999859342 GO:0005184 neuropeptide hormone activity 3/1553 31/18639 0.0967741935483871 1.1614772656461 0.483763185022417 0.999999999859342 GO:0016411 acylglycerol O-acyltransferase activity 3/1553 31/18639 0.0967741935483871 1.1614772656461 0.483763185022417 0.999999999859342 GO:0008200 ion channel inhibitor activity 4/1553 43/18639 0.0930232558139535 1.11645876697764 0.486634200740454 0.999999999859342 GO:0008173 RNA methyltransferase activity 6/1553 67/18639 0.0895522388059701 1.07479985776206 0.489612903213403 0.999999999859342 GO:0016500 protein-hormone receptor activity 6/1553 67/18639 0.0895522388059701 1.07479985776206 0.489612903213403 0.999999999859342 GO:0042054 histone methyltransferase activity 6/1553 67/18639 0.0895522388059701 1.07479985776206 0.489612903213403 0.999999999859342 GO:0072341 modified amino acid binding 8/1553 91/18639 0.0879120879120879 1.05511487868217 0.491219355632327 0.999999999859342 GO:0046906 tetrapyrrole binding 13/1553 152/18639 0.0855263157894737 1.02648100450741 0.503124020387627 0.999999999859342 GO:0140223 general transcription initiation factor activity 6/1553 68/18639 0.0882352941176471 1.05899397750085 0.504325413439084 0.999999999859342 GO:0016248 channel inhibitor activity 4/1553 44/18639 0.0909090909090909 1.09108470409179 0.504982513934332 0.999999999859342 GO:0031369 translation initiation factor binding 3/1553 32/18639 0.09375 1.12518110109466 0.505361211755486 0.999999999859342 GO:0047498 calcium-dependent phospholipase A2 activity 3/1553 32/18639 0.09375 1.12518110109466 0.505361211755486 0.999999999859342 GO:0160041 neuropeptide activity 3/1553 32/18639 0.09375 1.12518110109466 0.505361211755486 0.999999999859342 GO:0016408 C-acyltransferase activity 2/1553 20/18639 0.1 1.20019317450097 0.505478937978317 0.999999999859342 GO:0030742 GTP-dependent protein binding 2/1553 20/18639 0.1 1.20019317450097 0.505478937978317 0.999999999859342 GO:0042288 MHC class I protein binding 2/1553 20/18639 0.1 1.20019317450097 0.505478937978317 0.999999999859342 GO:0052745 inositol phosphate phosphatase activity 2/1553 20/18639 0.1 1.20019317450097 0.505478937978317 0.999999999859342 GO:0061608 nuclear import signal receptor activity 2/1553 20/18639 0.1 1.20019317450097 0.505478937978317 0.999999999859342 GO:0002039 p53 binding 6/1553 69/18639 0.0869565217391304 1.04364623869649 0.518882734537585 0.999999999859342 GO:0141110 transporter inhibitor activity 4/1553 45/18639 0.0888888888888889 1.06683837733419 0.523033098283553 0.999999999859342 GO:0030296 protein tyrosine kinase activator activity 3/1553 33/18639 0.0909090909090909 1.09108470409179 0.526480004581752 0.999999999859342 GO:0140311 protein sequestering activity 3/1553 33/18639 0.0909090909090909 1.09108470409179 0.526480004581752 0.999999999859342 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 14/1553 167/18639 0.0838323353293413 1.00614996664752 0.531136082915461 0.999999999859342 GO:0016874 ligase activity 14/1553 167/18639 0.0838323353293413 1.00614996664752 0.531136082915461 0.999999999859342 GO:0005123 death receptor binding 2/1553 21/18639 0.0952380952380952 1.14304111857235 0.532082073013248 0.999999999859342 GO:0019200 carbohydrate kinase activity 2/1553 21/18639 0.0952380952380952 1.14304111857235 0.532082073013248 0.999999999859342 GO:0035613 RNA stem-loop binding 2/1553 21/18639 0.0952380952380952 1.14304111857235 0.532082073013248 0.999999999859342 GO:0070182 DNA polymerase binding 2/1553 21/18639 0.0952380952380952 1.14304111857235 0.532082073013248 0.999999999859342 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1553 70/18639 0.0857142857142857 1.02873700671511 0.533269884609209 0.999999999859342 GO:0016247 channel regulator activity 14/1553 168/18639 0.0833333333333333 1.0001609787508 0.540402694080124 0.999999999859342 GO:0008276 protein methyltransferase activity 8/1553 95/18639 0.0842105263157895 1.01068898905344 0.541123566845987 0.999999999859342 GO:0008175 tRNA methyltransferase activity 3/1553 34/18639 0.0882352941176471 1.05899397750085 0.547088463012918 0.999999999859342 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 3/1553 34/18639 0.0882352941176471 1.05899397750085 0.547088463012918 0.999999999859342 GO:0090482 vitamin transmembrane transporter activity 3/1553 34/18639 0.0882352941176471 1.05899397750085 0.547088463012918 0.999999999859342 GO:0140299 molecular sensor activity 6/1553 71/18639 0.0845070422535211 1.01424775309941 0.54747293170287 0.999999999859342 GO:0070063 RNA polymerase binding 5/1553 59/18639 0.0847457627118644 1.01711285974658 0.552003173819029 0.999999999859342 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1553 22/18639 0.0909090909090909 1.09108470409179 0.557688340653339 0.999999999859342 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1553 22/18639 0.0909090909090909 1.09108470409179 0.557688340653339 0.999999999859342 GO:0033691 sialic acid binding 2/1553 22/18639 0.0909090909090909 1.09108470409179 0.557688340653339 0.999999999859342 GO:0140517 protein-RNA adaptor activity 2/1553 22/18639 0.0909090909090909 1.09108470409179 0.557688340653339 0.999999999859342 GO:0140784 metal ion sensor activity 2/1553 22/18639 0.0909090909090909 1.09108470409179 0.557688340653339 0.999999999859342 GO:0043495 protein-membrane adaptor activity 4/1553 47/18639 0.0851063829787234 1.02144099957529 0.558147487525723 0.999999999859342 GO:0140938 histone H3 methyltransferase activity 4/1553 47/18639 0.0851063829787234 1.02144099957529 0.558147487525723 0.999999999859342 GO:0030246 carbohydrate binding 23/1553 280/18639 0.0821428571428571 0.985872964768651 0.560400511156196 0.999999999859342 GO:0005154 epidermal growth factor receptor binding 3/1553 35/18639 0.0857142857142857 1.02873700671511 0.567160733219986 0.999999999859342 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/1553 60/18639 0.0833333333333333 1.0001609787508 0.567298357605435 0.999999999859342 GO:0004222 metalloendopeptidase activity 9/1553 110/18639 0.0818181818181818 0.981976233682608 0.572929201187779 0.999999999859342 GO:0008237 metallopeptidase activity 15/1553 184/18639 0.0815217391304348 0.978418348777961 0.574308186544107 0.999999999859342 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/1553 48/18639 0.0833333333333333 1.0001609787508 0.575171236833125 0.999999999859342 GO:0015297 antiporter activity 11/1553 135/18639 0.0814814814814815 0.977935179223009 0.576268412860575 0.999999999859342 GO:0008170 N-methyltransferase activity 8/1553 98/18639 0.0816326530612245 0.97974953020487 0.577245055443882 0.999999999859342 GO:0004518 nuclease activity 17/1553 209/18639 0.0813397129186603 0.976233682608441 0.578107558370732 0.999999999859342 GO:0000182 rDNA binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0004935 adrenergic receptor activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0004955 prostaglandin receptor activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0005131 growth hormone receptor binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0005337 nucleoside transmembrane transporter activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0005522 profilin binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0008140 cAMP response element binding protein binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0008190 eukaryotic initiation factor 4E binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0008401 retinoic acid 4-hydroxylase activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0015203 polyamine transmembrane transporter activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0019911 structural constituent of myelin sheath 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0032356 oxidized DNA binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0035256 G protein-coupled glutamate receptor binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0035374 chondroitin sulfate binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0043422 protein kinase B binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0050308 sugar-phosphatase activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0051378 serotonin binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0051864 histone H3K36 demethylase activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0051880 G-quadruplex DNA binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0070513 death domain binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0140999 histone H3K4 trimethyltransferase activity 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:1990763 arrestin family protein binding 1/1553 10/18639 0.1 1.20019317450097 0.581126775134594 0.999999999859342 GO:0003887 DNA-directed DNA polymerase activity 2/1553 23/18639 0.0869565217391304 1.04364623869649 0.582279086945151 0.999999999859342 GO:0005212 structural constituent of eye lens 2/1553 23/18639 0.0869565217391304 1.04364623869649 0.582279086945151 0.999999999859342 GO:0016493 C-C chemokine receptor activity 2/1553 23/18639 0.0869565217391304 1.04364623869649 0.582279086945151 0.999999999859342 GO:0099186 structural constituent of postsynapse 2/1553 23/18639 0.0869565217391304 1.04364623869649 0.582279086945151 0.999999999859342 GO:0140789 histone phosphatase activity 11/1553 136/18639 0.0808823529411765 0.970744479375781 0.586321095346787 0.999999999859342 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/1553 36/18639 0.0833333333333333 1.0001609787508 0.586675821802919 0.999999999859342 GO:0003684 damaged DNA binding 6/1553 74/18639 0.0810810810810811 0.973129600946729 0.58885374070884 0.999999999859342 GO:0005004 GPI-linked ephrin receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0005008 hepatocyte growth factor receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0005009 insulin receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0005011 macrophage colony-stimulating factor receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0005020 stem cell factor receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0008288 boss receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0035254 glutamate receptor binding 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0036332 placental growth factor receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0038062 protein tyrosine kinase collagen receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0060175 brain-derived neurotrophic factor receptor activity 4/1553 49/18639 0.0816326530612245 0.97974953020487 0.591816924786607 0.999999999859342 GO:0019213 deacetylase activity 3/1553 37/18639 0.0810810810810811 0.973129600946729 0.605617214876413 0.999999999859342 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1553 24/18639 0.0833333333333333 1.0001609787508 0.605845679138095 0.999999999859342 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1553 24/18639 0.0833333333333333 1.0001609787508 0.605845679138095 0.999999999859342 GO:0070840 dynein complex binding 2/1553 24/18639 0.0833333333333333 1.0001609787508 0.605845679138095 0.999999999859342 GO:0004197 cysteine-type endopeptidase activity 7/1553 88/18639 0.0795454545454545 0.954699116080314 0.607187062899717 0.999999999859342 GO:0005007 fibroblast growth factor receptor activity 4/1553 50/18639 0.08 0.960154539600773 0.608070753694562 0.999999999859342 GO:0032813 tumor necrosis factor receptor superfamily binding 4/1553 50/18639 0.08 0.960154539600773 0.608070753694562 0.999999999859342 GO:0005507 copper ion binding 5/1553 63/18639 0.0793650793650794 0.952534265476957 0.611498090508092 0.999999999859342 GO:0140101 catalytic activity, acting on a tRNA 11/1553 139/18639 0.079136690647482 0.949793159677023 0.61582237236594 0.999999999859342 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0001851 complement component C3b binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0002162 dystroglycan binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0004954 prostanoid receptor activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0005225 volume-sensitive anion channel activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0005536 D-glucose binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0008046 axon guidance receptor activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0008503 benzodiazepine receptor activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0008526 phosphatidylinositol transfer activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0016594 glycine binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0019203 carbohydrate phosphatase activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0019206 nucleoside kinase activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0019215 intermediate filament binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0032050 clathrin heavy chain binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0035252 UDP-xylosyltransferase activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0042285 xylosyltransferase activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0048407 platelet-derived growth factor binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0070697 activin receptor binding 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0140537 transcription regulator activator activity 1/1553 11/18639 0.0909090909090909 1.09108470409179 0.616045993461717 0.999999999859342 GO:0140098 catalytic activity, acting on RNA 31/1553 387/18639 0.0801033591731266 0.961395049341859 0.618614028004874 0.999999999859342 GO:0003743 translation initiation factor activity 4/1553 51/18639 0.0784313725490196 0.941327980000757 0.623921196280235 0.999999999859342 GO:0005010 insulin-like growth factor receptor activity 4/1553 51/18639 0.0784313725490196 0.941327980000757 0.623921196280235 0.999999999859342 GO:0005030 neurotrophin receptor activity 4/1553 51/18639 0.0784313725490196 0.941327980000757 0.623921196280235 0.999999999859342 GO:0043531 ADP binding 3/1553 38/18639 0.0789473684210526 0.947520927237605 0.623972506140794 0.999999999859342 GO:0004713 protein tyrosine kinase activity 11/1553 140/18639 0.0785714285714286 0.943008922822187 0.625422694325711 0.999999999859342 GO:0004536 DNA nuclease activity 5/1553 64/18639 0.078125 0.93765091757888 0.625632694435295 0.999999999859342 GO:0000030 mannosyltransferase activity 2/1553 25/18639 0.08 0.960154539600773 0.628387967148767 0.999999999859342 GO:0003707 nuclear steroid receptor activity 2/1553 25/18639 0.08 0.960154539600773 0.628387967148767 0.999999999859342 GO:0008483 transaminase activity 2/1553 25/18639 0.08 0.960154539600773 0.628387967148767 0.999999999859342 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1553 25/18639 0.08 0.960154539600773 0.628387967148767 0.999999999859342 GO:0017025 TBP-class protein binding 2/1553 25/18639 0.08 0.960154539600773 0.628387967148767 0.999999999859342 GO:0042974 nuclear retinoic acid receptor binding 2/1553 25/18639 0.08 0.960154539600773 0.628387967148767 0.999999999859342 GO:0008168 methyltransferase activity 16/1553 204/18639 0.0784313725490196 0.941327980000757 0.637241434697791 0.999999999859342 GO:0005506 iron ion binding 12/1553 154/18639 0.0779220779220779 0.935215460650103 0.638634835556777 0.999999999859342 GO:0038024 cargo receptor activity 5/1553 65/18639 0.0769230769230769 0.923225518846897 0.639453128413207 0.999999999859342 GO:0000217 DNA secondary structure binding 3/1553 39/18639 0.0769230769230769 0.923225518846897 0.641733036804111 0.999999999859342 GO:0020037 heme binding 11/1553 142/18639 0.0774647887323944 0.92972710700779 0.644249833436537 0.999999999859342 GO:0000287 magnesium ion binding 18/1553 230/18639 0.0782608695652174 0.939281614826843 0.644833800033815 0.999999999859342 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0004032 aldose reductase (NADPH) activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0004126 cytidine deaminase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0004859 phospholipase inhibitor activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0005165 neurotrophin receptor binding 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0010853 cyclase activator activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0015166 polyol transmembrane transporter activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0016208 AMP binding 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0016273 arginine N-methyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0016274 protein-arginine N-methyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0016423 tRNA (guanine) methyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0016801 hydrolase activity, acting on ether bonds 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0016803 ether hydrolase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0031543 peptidyl-proline dioxygenase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0045295 gamma-catenin binding 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0140900 chloride:bicarbonate antiporter activity 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:1990459 transferrin receptor binding 1/1553 12/18639 0.0833333333333333 1.0001609787508 0.648055901780052 0.999999999859342 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1553 26/18639 0.0769230769230769 0.923225518846897 0.649912931575527 0.999999999859342 GO:0004435 phosphatidylinositol phospholipase C activity 2/1553 26/18639 0.0769230769230769 0.923225518846897 0.649912931575527 0.999999999859342 GO:0004950 chemokine receptor activity 2/1553 26/18639 0.0769230769230769 0.923225518846897 0.649912931575527 0.999999999859342 GO:0034237 protein kinase A regulatory subunit binding 2/1553 26/18639 0.0769230769230769 0.923225518846897 0.649912931575527 0.999999999859342 GO:0050750 low-density lipoprotein particle receptor binding 2/1553 26/18639 0.0769230769230769 0.923225518846897 0.649912931575527 0.999999999859342 GO:0097602 cullin family protein binding 2/1553 26/18639 0.0769230769230769 0.923225518846897 0.649912931575527 0.999999999859342 GO:0016798 hydrolase activity, acting on glycosyl bonds 10/1553 130/18639 0.0769230769230769 0.923225518846897 0.650616743938155 0.999999999859342 GO:0038064 collagen receptor activity 4/1553 53/18639 0.0754716981132075 0.905806169434691 0.654376391445211 0.999999999859342 GO:0051018 protein kinase A binding 4/1553 53/18639 0.0754716981132075 0.905806169434691 0.654376391445211 0.999999999859342 GO:0140375 immune receptor activity 12/1553 156/18639 0.0769230769230769 0.923225518846897 0.656361884853372 0.999999999859342 GO:0046982 protein heterodimerization activity 29/1553 369/18639 0.0785907859078591 0.943241248252792 0.657639521176239 0.999999999859342 GO:0004532 RNA exonuclease activity 3/1553 40/18639 0.075 0.900144880875724 0.658893549539613 0.999999999859342 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1553 40/18639 0.075 0.900144880875724 0.658893549539613 0.999999999859342 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/1553 40/18639 0.075 0.900144880875724 0.658893549539613 0.999999999859342 GO:0050997 quaternary ammonium group binding 3/1553 40/18639 0.075 0.900144880875724 0.658893549539613 0.999999999859342 GO:0001671 ATPase activator activity 2/1553 27/18639 0.0740740740740741 0.889031981111826 0.670433497887853 0.999999999859342 GO:0004364 glutathione transferase activity 2/1553 27/18639 0.0740740740740741 0.889031981111826 0.670433497887853 0.999999999859342 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/1553 27/18639 0.0740740740740741 0.889031981111826 0.670433497887853 0.999999999859342 GO:0005385 zinc ion transmembrane transporter activity 2/1553 27/18639 0.0740740740740741 0.889031981111826 0.670433497887853 0.999999999859342 GO:0008320 protein transmembrane transporter activity 2/1553 27/18639 0.0740740740740741 0.889031981111826 0.670433497887853 0.999999999859342 GO:0008395 steroid hydroxylase activity 2/1553 27/18639 0.0740740740740741 0.889031981111826 0.670433497887853 0.999999999859342 GO:0001727 lipid kinase activity 3/1553 41/18639 0.0731707317073171 0.878190127683633 0.675451858086342 0.999999999859342 GO:0015101 organic cation transmembrane transporter activity 6/1553 81/18639 0.0740740740740741 0.889031981111826 0.677039888870617 0.999999999859342 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0004993 G protein-coupled serotonin receptor activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0008253 5'-nucleotidase activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0009982 pseudouridine synthase activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0017154 semaphorin receptor activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0019104 DNA N-glycosylase activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0031432 titin binding 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0032396 inhibitory MHC class I receptor activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0035673 oligopeptide transmembrane transporter activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0045159 myosin II binding 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0046974 histone H3K9 methyltransferase activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0070700 BMP receptor binding 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0071837 HMG box domain binding 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0097157 pre-mRNA intronic binding 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:1901338 catecholamine binding 1/1553 13/18639 0.0769230769230769 0.923225518846897 0.677398747355592 0.999999999859342 GO:0008374 O-acyltransferase activity 4/1553 55/18639 0.0727272727272727 0.87286776327343 0.683130781010741 0.999999999859342 GO:0036408 histone H3K14 acetyltransferase activity 2/1553 28/18639 0.0714285714285714 0.857280838929261 0.689967498512087 0.999999999859342 GO:0046625 sphingolipid binding 2/1553 28/18639 0.0714285714285714 0.857280838929261 0.689967498512087 0.999999999859342 GO:0046966 nuclear thyroid hormone receptor binding 2/1553 28/18639 0.0714285714285714 0.857280838929261 0.689967498512087 0.999999999859342 GO:0050698 proteoglycan sulfotransferase activity 2/1553 28/18639 0.0714285714285714 0.857280838929261 0.689967498512087 0.999999999859342 GO:0004520 DNA endonuclease activity 3/1553 42/18639 0.0714285714285714 0.857280838929261 0.691408533615679 0.999999999859342 GO:0048487 beta-tubulin binding 3/1553 42/18639 0.0714285714285714 0.857280838929261 0.691408533615679 0.999999999859342 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 9/1553 122/18639 0.0737704918032787 0.885388407418745 0.696519098278099 0.999999999859342 GO:0170055 lipid transmembrane transporter activity 4/1553 56/18639 0.0714285714285714 0.857280838929261 0.696861786548069 0.999999999859342 GO:0008135 translation factor activity, RNA binding 6/1553 83/18639 0.072289156626506 0.867609523735638 0.699854760883048 0.999999999859342 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1553 70/18639 0.0714285714285714 0.857280838929261 0.703642224067994 0.999999999859342 GO:0004065 arylsulfatase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0005313 L-glutamate transmembrane transporter activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0008174 mRNA methyltransferase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0008195 phosphatidate phosphatase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0008331 high voltage-gated calcium channel activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0008494 translation activator activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0015926 glucosidase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0016530 metallochaperone activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0034236 protein kinase A catalytic subunit binding 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0042813 Wnt receptor activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0061665 SUMO ligase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0098599 palmitoyl hydrolase activity 1/1553 14/18639 0.0714285714285714 0.857280838929261 0.704296618361539 0.999999999859342 GO:0008375 acetylglucosaminyltransferase activity 3/1553 43/18639 0.0697674418604651 0.837344075233232 0.706766608581321 0.999999999859342 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1553 43/18639 0.0697674418604651 0.837344075233232 0.706766608581321 0.999999999859342 GO:0004629 phospholipase C activity 2/1553 29/18639 0.0689655172413793 0.827719430690321 0.708536766424501 0.999999999859342 GO:0010484 histone H3 acetyltransferase activity 2/1553 29/18639 0.0689655172413793 0.827719430690321 0.708536766424501 0.999999999859342 GO:0035250 UDP-galactosyltransferase activity 2/1553 29/18639 0.0689655172413793 0.827719430690321 0.708536766424501 0.999999999859342 GO:0099604 ligand-gated calcium channel activity 2/1553 29/18639 0.0689655172413793 0.827719430690321 0.708536766424501 0.999999999859342 GO:0180051 translation factor activity 6/1553 84/18639 0.0714285714285714 0.857280838929261 0.710847202602454 0.999999999859342 GO:0016741 transferase activity, transferring one-carbon groups 16/1553 215/18639 0.0744186046511628 0.893167013582114 0.718034300517137 0.999999999859342 GO:0004725 protein tyrosine phosphatase activity 7/1553 98/18639 0.0714285714285714 0.857280838929261 0.718112121847801 0.999999999859342 GO:0042626 ATPase-coupled transmembrane transporter activity 7/1553 98/18639 0.0714285714285714 0.857280838929261 0.718112121847801 0.999999999859342 GO:0008408 3'-5' exonuclease activity 4/1553 58/18639 0.0689655172413793 0.827719430690321 0.723028201571526 0.999999999859342 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0016769 transferase activity, transferring nitrogenous groups 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0033612 receptor serine/threonine kinase binding 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0043995 histone H4K5 acetyltransferase activity 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0043996 histone H4K8 acetyltransferase activity 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0043997 histone H4K12 acetyltransferase activity 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0051721 protein phosphatase 2A binding 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0098918 structural constituent of synapse 2/1553 30/18639 0.0666666666666667 0.800128783000644 0.726166345564399 0.999999999859342 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0004953 icosanoid receptor activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0005041 low-density lipoprotein particle receptor activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0008242 omega peptidase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0008252 nucleotidase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0010181 FMN binding 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0015116 sulfate transmembrane transporter activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0015250 water channel activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0015929 hexosaminidase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0030553 cGMP binding 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0031005 filamin binding 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0034483 heparan sulfate sulfotransferase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0042809 nuclear vitamin D receptor binding 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0045504 dynein heavy chain binding 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0047372 monoacylglycerol lipase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0048531 beta-1,3-galactosyltransferase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0050780 dopamine receptor binding 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0061578 K63-linked deubiquitinase activity 1/1553 15/18639 0.0666666666666667 0.800128783000644 0.728953120465406 0.999999999859342 GO:0070851 growth factor receptor binding 10/1553 139/18639 0.0719424460431655 0.863448326979112 0.73092668620636 0.999999999859342 GO:0036002 pre-mRNA binding 4/1553 59/18639 0.0677966101694915 0.813690287797265 0.735466385408072 0.999999999859342 GO:0045309 protein phosphorylated amino acid binding 4/1553 59/18639 0.0677966101694915 0.813690287797265 0.735466385408072 0.999999999859342 GO:0005164 tumor necrosis factor receptor binding 2/1553 31/18639 0.0645161290322581 0.774318177097397 0.742883804912122 0.999999999859342 GO:0005452 solute:inorganic anion antiporter activity 2/1553 31/18639 0.0645161290322581 0.774318177097397 0.742883804912122 0.999999999859342 GO:0008327 methyl-CpG binding 2/1553 31/18639 0.0645161290322581 0.774318177097397 0.742883804912122 0.999999999859342 GO:0017147 Wnt-protein binding 2/1553 31/18639 0.0645161290322581 0.774318177097397 0.742883804912122 0.999999999859342 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/1553 60/18639 0.0666666666666667 0.800128783000644 0.747478387393974 0.999999999859342 GO:0031491 nucleosome binding 5/1553 74/18639 0.0675675675675676 0.810941334122274 0.748935271314664 0.999999999859342 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/1553 46/18639 0.0652173913043478 0.782734679022369 0.749310755520522 0.999999999859342 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1553 46/18639 0.0652173913043478 0.782734679022369 0.749310755520522 0.999999999859342 GO:0005516 calmodulin binding 15/1553 207/18639 0.072463768115942 0.869705198913743 0.750715739137765 0.999999999859342 GO:0000062 fatty-acyl-CoA binding 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0003688 DNA replication origin binding 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0005521 lamin binding 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0008142 oxysterol binding 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0008296 3'-5'-DNA exonuclease activity 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0022841 potassium ion leak channel activity 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0030275 LRR domain binding 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/1553 16/18639 0.0625 0.750120734063104 0.751554914060618 0.999999999859342 GO:0016791 phosphatase activity 20/1553 273/18639 0.0732600732600733 0.879262398901807 0.758533188554233 0.999999999859342 GO:0008378 galactosyltransferase activity 2/1553 32/18639 0.0625 0.750120734063104 0.758718644455898 0.999999999859342 GO:0015106 bicarbonate transmembrane transporter activity 2/1553 32/18639 0.0625 0.750120734063104 0.758718644455898 0.999999999859342 GO:0022884 macromolecule transmembrane transporter activity 2/1553 32/18639 0.0625 0.750120734063104 0.758718644455898 0.999999999859342 GO:0140142 nucleocytoplasmic carrier activity 2/1553 32/18639 0.0625 0.750120734063104 0.758718644455898 0.999999999859342 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/1553 89/18639 0.0674157303370786 0.809118994045595 0.761621943695388 0.999999999859342 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/1553 89/18639 0.0674157303370786 0.809118994045595 0.761621943695388 0.999999999859342 GO:0140359 ABC-type transporter activity 3/1553 47/18639 0.0638297872340425 0.766080749681468 0.762344614701985 0.999999999859342 GO:0015291 secondary active transmembrane transporter activity 21/1553 287/18639 0.0731707317073171 0.878190127683633 0.764612372350042 0.999999999859342 GO:0005253 monoatomic anion channel activity 7/1553 103/18639 0.0679611650485437 0.815665264223957 0.764850944572474 0.999999999859342 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/1553 130/18639 0.0692307692307692 0.830902966962207 0.765066227847011 0.999999999859342 GO:0015179 L-amino acid transmembrane transporter activity 4/1553 62/18639 0.0645161290322581 0.774318177097397 0.770241568128589 0.999999999859342 GO:0140793 histone H2AXY142 phosphatase activity 6/1553 90/18639 0.0666666666666667 0.800128783000644 0.77094227239054 0.999999999859342 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0008484 sulfuric ester hydrolase activity 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0016805 dipeptidase activity 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0019198 transmembrane receptor protein phosphatase activity 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0031489 myosin V binding 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0036041 long-chain fatty acid binding 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0045125 bioactive lipid receptor activity 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0045236 CXCR chemokine receptor binding 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0070402 NADPH binding 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:1901567 fatty acid derivative binding 1/1553 17/18639 0.0588235294117647 0.705995985000568 0.772273123718775 0.999999999859342 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/1553 48/18639 0.0625 0.750120734063104 0.774822839893243 0.999999999859342 GO:0001217 DNA-binding transcription repressor activity 20/1553 278/18639 0.0719424460431655 0.863448326979112 0.785390389107551 0.999999999859342 GO:0140030 modification-dependent protein binding 12/1553 173/18639 0.069364161849711 0.832503936070034 0.785966548406787 0.999999999859342 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1553 34/18639 0.0588235294117647 0.705995985000568 0.787865114981006 0.999999999859342 GO:0016831 carboxy-lyase activity 2/1553 34/18639 0.0588235294117647 0.705995985000568 0.787865114981006 0.999999999859342 GO:0052689 carboxylic ester hydrolase activity 6/1553 92/18639 0.0652173913043478 0.782734679022369 0.788760940341425 0.999999999859342 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1553 18/18639 0.0555555555555556 0.66677398583387 0.791264630477702 0.999999999859342 GO:0005372 water transmembrane transporter activity 1/1553 18/18639 0.0555555555555556 0.66677398583387 0.791264630477702 0.999999999859342 GO:0008308 voltage-gated monoatomic anion channel activity 1/1553 18/18639 0.0555555555555556 0.66677398583387 0.791264630477702 0.999999999859342 GO:0008525 phosphatidylcholine transporter activity 1/1553 18/18639 0.0555555555555556 0.66677398583387 0.791264630477702 0.999999999859342 GO:0017075 syntaxin-1 binding 1/1553 18/18639 0.0555555555555556 0.66677398583387 0.791264630477702 0.999999999859342 GO:0030228 lipoprotein particle receptor activity 1/1553 18/18639 0.0555555555555556 0.66677398583387 0.791264630477702 0.999999999859342 GO:0031690 adrenergic receptor binding 1/1553 18/18639 0.0555555555555556 0.66677398583387 0.791264630477702 0.999999999859342 GO:0005216 monoatomic ion channel activity 33/1553 448/18639 0.0736607142857143 0.884070865145801 0.796346579165766 0.999999999859342 GO:0051213 dioxygenase activity 6/1553 93/18639 0.0645161290322581 0.774318177097397 0.79726445507179 0.999999999859342 GO:0015370 solute:sodium symporter activity 5/1553 79/18639 0.0632911392405063 0.759615933228459 0.798047841461577 0.999999999859342 GO:0004721 phosphoprotein phosphatase activity 12/1553 175/18639 0.0685714285714286 0.822989605372091 0.798606294060722 0.999999999859342 GO:0000175 3'-5'-RNA exonuclease activity 2/1553 35/18639 0.0571428571428571 0.685824671143409 0.801241138118037 0.999999999859342 GO:0010485 histone H4 acetyltransferase activity 2/1553 35/18639 0.0571428571428571 0.685824671143409 0.801241138118037 0.999999999859342 GO:0034061 DNA polymerase activity 2/1553 35/18639 0.0571428571428571 0.685824671143409 0.801241138118037 0.999999999859342 GO:0008528 G protein-coupled peptide receptor activity 8/1553 122/18639 0.0655737704918033 0.787011917705551 0.806882613018537 0.999999999859342 GO:0022840 leak channel activity 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0022842 narrow pore channel activity 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0031420 alkali metal ion binding 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0042577 lipid phosphatase activity 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0042834 peptidoglycan binding 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0046624 sphingolipid transporter activity 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0097001 ceramide binding 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0099589 serotonin receptor activity 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0120227 acyl-CoA binding 1/1553 19/18639 0.0526315789473684 0.631680618158403 0.808673256699072 0.999999999859342 GO:0016779 nucleotidyltransferase activity 9/1553 136/18639 0.0661764705882353 0.794245483125639 0.808752215649978 0.999999999859342 GO:0016597 amino acid binding 3/1553 51/18639 0.0588235294117647 0.705995985000568 0.809053726550139 0.999999999859342 GO:0016830 carbon-carbon lyase activity 3/1553 51/18639 0.0588235294117647 0.705995985000568 0.809053726550139 0.999999999859342 GO:0004620 phospholipase activity 7/1553 109/18639 0.0642201834862385 0.770766258853831 0.813159829600231 0.999999999859342 GO:0000993 RNA polymerase II complex binding 2/1553 36/18639 0.0555555555555556 0.66677398583387 0.813862627313044 0.999999999859342 GO:0004033 aldo-keto reductase (NADPH) activity 2/1553 36/18639 0.0555555555555556 0.66677398583387 0.813862627313044 0.999999999859342 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1553 67/18639 0.0597014925373134 0.716533238508039 0.820087221822355 0.999999999859342 GO:0005326 neurotransmitter transmembrane transporter activity 1/1553 20/18639 0.05 0.600096587250483 0.824630852421217 0.999999999859342 GO:0030627 pre-mRNA 5'-splice site binding 1/1553 20/18639 0.05 0.600096587250483 0.824630852421217 0.999999999859342 GO:0031418 L-ascorbic acid binding 1/1553 20/18639 0.05 0.600096587250483 0.824630852421217 0.999999999859342 GO:0140664 ATP-dependent DNA damage sensor activity 1/1553 20/18639 0.05 0.600096587250483 0.824630852421217 0.999999999859342 GO:0140939 histone H4 methyltransferase activity 1/1553 20/18639 0.05 0.600096587250483 0.824630852421217 0.999999999859342 GO:0030280 structural constituent of skin epidermis 2/1553 37/18639 0.0540540540540541 0.648753067297819 0.825762365166566 0.999999999859342 GO:0140767 enzyme-substrate adaptor activity 9/1553 139/18639 0.0647482014388489 0.777103494281201 0.828167810647972 0.999999999859342 GO:0030145 manganese ion binding 4/1553 68/18639 0.0588235294117647 0.705995985000568 0.828907282758121 0.999999999859342 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 12/1553 181/18639 0.0662983425414365 0.795708181989591 0.833254495915608 0.999999999859342 GO:0005261 monoatomic cation channel activity 24/1553 341/18639 0.0703812316715543 0.844710738651706 0.834183347873506 0.999999999859342 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/1553 38/18639 0.0526315789473684 0.631680618158403 0.83697291289022 0.999999999859342 GO:0016279 protein-lysine N-methyltransferase activity 4/1553 69/18639 0.0579710144927536 0.695764159130995 0.837364791158651 0.999999999859342 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1553 21/18639 0.0476190476190476 0.571520559286174 0.839258291391616 0.999999999859342 GO:0001846 opsonin binding 1/1553 21/18639 0.0476190476190476 0.571520559286174 0.839258291391616 0.999999999859342 GO:0005248 voltage-gated sodium channel activity 1/1553 21/18639 0.0476190476190476 0.571520559286174 0.839258291391616 0.999999999859342 GO:0015125 bile acid transmembrane transporter activity 1/1553 21/18639 0.0476190476190476 0.571520559286174 0.839258291391616 0.999999999859342 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1553 21/18639 0.0476190476190476 0.571520559286174 0.839258291391616 0.999999999859342 GO:0061891 calcium ion sensor activity 1/1553 21/18639 0.0476190476190476 0.571520559286174 0.839258291391616 0.999999999859342 GO:1904047 S-adenosyl-L-methionine binding 1/1553 21/18639 0.0476190476190476 0.571520559286174 0.839258291391616 0.999999999859342 GO:0004527 exonuclease activity 5/1553 84/18639 0.0595238095238095 0.714400699107718 0.839266017374863 0.999999999859342 GO:0016278 lysine N-methyltransferase activity 4/1553 70/18639 0.0571428571428571 0.685824671143409 0.845469189164146 0.999999999859342 GO:0001653 peptide receptor activity 8/1553 128/18639 0.0625 0.750120734063104 0.846183097157691 0.999999999859342 GO:0005243 gap junction channel activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0008970 phospholipase A1 activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0016881 acid-amino acid ligase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0032931 histone H3K56 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0043992 histone H3K9 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0043993 histone H3K18 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0043994 histone H3K23 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0043999 histone H2AK5 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0044012 histone H2AK9 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0044014 histone H2BK5 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0044015 histone H2BK12 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0044016 histone H3K4 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0044017 histone H3K27 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0044018 histone H3K36 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0046972 histone H4K16 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0050321 tau-protein kinase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0140908 histone H3K122 acetyltransferase activity 1/1553 22/18639 0.0454545454545455 0.545542352045894 0.852666384283915 0.999999999859342 GO:0017124 SH3 domain binding 7/1553 115/18639 0.0608695652173913 0.730552367087544 0.853408509493974 0.999999999859342 GO:0035401 histone H3Y41 kinase activity 7/1553 115/18639 0.0608695652173913 0.730552367087544 0.853408509493974 0.999999999859342 GO:0140801 histone H2AXY142 kinase activity 7/1553 115/18639 0.0608695652173913 0.730552367087544 0.853408509493974 0.999999999859342 GO:0016757 glycosyltransferase activity 18/1553 267/18639 0.0674157303370786 0.809118994045595 0.856364654122469 0.999999999859342 GO:0004177 aminopeptidase activity 2/1553 40/18639 0.05 0.600096587250483 0.857454465503899 0.999999999859342 GO:0015144 carbohydrate transmembrane transporter activity 2/1553 40/18639 0.05 0.600096587250483 0.857454465503899 0.999999999859342 GO:0032451 demethylase activity 2/1553 40/18639 0.05 0.600096587250483 0.857454465503899 0.999999999859342 GO:0071855 neuropeptide receptor binding 2/1553 40/18639 0.05 0.600096587250483 0.857454465503899 0.999999999859342 GO:0015294 solute:monoatomic cation symporter activity 7/1553 116/18639 0.0603448275862069 0.724254501854031 0.859381462530325 0.999999999859342 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 18/1553 268/18639 0.0671641791044776 0.806099893321544 0.860357866167663 0.999999999859342 GO:0015171 amino acid transmembrane transporter activity 6/1553 102/18639 0.0588235294117647 0.705995985000568 0.862280924148009 0.999999999859342 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1553 23/18639 0.0434782608695652 0.521823119348246 0.864956715981131 0.999999999859342 GO:0043274 phospholipase binding 1/1553 23/18639 0.0434782608695652 0.521823119348246 0.864956715981131 0.999999999859342 GO:0044013 histone H2B acetyltransferase activity 1/1553 23/18639 0.0434782608695652 0.521823119348246 0.864956715981131 0.999999999859342 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1553 23/18639 0.0434782608695652 0.521823119348246 0.864956715981131 0.999999999859342 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1553 23/18639 0.0434782608695652 0.521823119348246 0.864956715981131 0.999999999859342 GO:0008227 G protein-coupled amine receptor activity 2/1553 41/18639 0.0487804878048781 0.585460085122422 0.866787932550954 0.999999999859342 GO:0042169 SH2 domain binding 2/1553 41/18639 0.0487804878048781 0.585460085122422 0.866787932550954 0.999999999859342 GO:0043175 RNA polymerase core enzyme binding 2/1553 42/18639 0.0476190476190476 0.571520559286174 0.875556902497717 0.999999999859342 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0005540 hyaluronic acid binding 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0015149 hexose transmembrane transporter activity 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0030552 cAMP binding 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0043998 histone H2A acetyltransferase activity 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0055056 D-glucose transmembrane transporter activity 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0140612 DNA damage sensor activity 1/1553 24/18639 0.0416666666666667 0.500080489375402 0.876222413235176 0.999999999859342 GO:0004674 protein serine/threonine kinase activity 30/1553 433/18639 0.069284064665127 0.83154261512769 0.878364300415389 0.999999999859342 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/1553 43/18639 0.0465116279069767 0.558229383488821 0.883790575371688 0.999999999859342 GO:0005319 lipid transporter activity 11/1553 178/18639 0.0617977528089888 0.741692411208462 0.884849171707807 0.999999999859342 GO:0000149 SNARE binding 6/1553 106/18639 0.0566037735849057 0.679354627076018 0.885081812506829 0.999999999859342 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/1553 91/18639 0.0549450549450549 0.659446799176355 0.885106700861698 0.999999999859342 GO:0001098 basal transcription machinery binding 3/1553 60/18639 0.05 0.600096587250483 0.886401575047572 0.999999999859342 GO:0001099 basal RNA polymerase II transcription machinery binding 3/1553 60/18639 0.05 0.600096587250483 0.886401575047572 0.999999999859342 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1553 60/18639 0.05 0.600096587250483 0.886401575047572 0.999999999859342 GO:0019842 vitamin binding 9/1553 150/18639 0.06 0.72011590470058 0.886526802715134 0.999999999859342 GO:0001848 complement binding 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0008139 nuclear localization sequence binding 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0015645 fatty acid ligase activity 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0015662 P-type ion transporter activity 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0017056 structural constituent of nuclear pore 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0120515 fatty acid-CoA ligase activity 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0140358 P-type transmembrane transporter activity 1/1553 25/18639 0.04 0.480077269800386 0.886548848488777 0.999999999859342 GO:0099094 ligand-gated monoatomic cation channel activity 8/1553 136/18639 0.0588235294117647 0.705995985000568 0.888370897662193 0.999999999859342 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1553 44/18639 0.0454545454545455 0.545542352045894 0.891517207606838 0.999999999859342 GO:0043014 alpha-tubulin binding 2/1553 44/18639 0.0454545454545455 0.545542352045894 0.891517207606838 0.999999999859342 GO:0019905 syntaxin binding 3/1553 61/18639 0.0491803278688525 0.590258938279164 0.892987773487838 0.999999999859342 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0004529 DNA exonuclease activity 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0008066 glutamate receptor activity 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0008143 poly(A) binding 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0015145 monosaccharide transmembrane transporter activity 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0019865 immunoglobulin binding 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0030247 polysaccharide binding 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0030507 spectrin binding 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0043548 phosphatidylinositol 3-kinase binding 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0120014 phospholipid transfer activity 1/1553 26/18639 0.0384615384615385 0.461612759423448 0.896014285165307 0.999999999859342 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/1553 45/18639 0.0444444444444444 0.533419188667096 0.898764066504765 0.999999999859342 GO:0042605 peptide antigen binding 2/1553 45/18639 0.0444444444444444 0.533419188667096 0.898764066504765 0.999999999859342 GO:0046915 transition metal ion transmembrane transporter activity 2/1553 45/18639 0.0444444444444444 0.533419188667096 0.898764066504765 0.999999999859342 GO:0005267 potassium channel activity 7/1553 124/18639 0.0564516129032258 0.677528404960223 0.900318566549607 0.999999999859342 GO:0016405 CoA-ligase activity 1/1553 27/18639 0.037037037037037 0.444515990555913 0.904690469291363 0.999999999859342 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1553 27/18639 0.037037037037037 0.444515990555913 0.904690469291363 0.999999999859342 GO:0035255 ionotropic glutamate receptor binding 1/1553 27/18639 0.037037037037037 0.444515990555913 0.904690469291363 0.999999999859342 GO:0030276 clathrin binding 2/1553 46/18639 0.0434782608695652 0.521823119348246 0.905557398822231 0.999999999859342 GO:0005543 phospholipid binding 34/1553 497/18639 0.06841046277666 0.821057704889997 0.906359410226578 0.999999999859342 GO:0000049 tRNA binding 4/1553 80/18639 0.05 0.600096587250483 0.909266330415718 0.999999999859342 GO:0001784 phosphotyrosine residue binding 2/1553 47/18639 0.0425531914893617 0.510720499787645 0.911922411449798 0.999999999859342 GO:0016866 intramolecular transferase activity 1/1553 28/18639 0.0357142857142857 0.428640419464631 0.912643171912817 0.999999999859342 GO:0019789 SUMO transferase activity 1/1553 28/18639 0.0357142857142857 0.428640419464631 0.912643171912817 0.999999999859342 GO:0051119 sugar transmembrane transporter activity 1/1553 28/18639 0.0357142857142857 0.428640419464631 0.912643171912817 0.999999999859342 GO:0141052 histone H3 demethylase activity 1/1553 28/18639 0.0357142857142857 0.428640419464631 0.912643171912817 0.999999999859342 GO:0160215 deacylase activity 3/1553 65/18639 0.0461538461538462 0.553935311308138 0.916030202977273 0.999999999859342 GO:0008234 cysteine-type peptidase activity 11/1553 187/18639 0.0588235294117647 0.705995985000568 0.917607757061147 0.999999999859342 GO:0008188 neuropeptide receptor activity 2/1553 48/18639 0.0416666666666667 0.500080489375402 0.917883262387039 0.999999999859342 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/1553 29/18639 0.0344827586206897 0.413859715345161 0.919932686394543 0.999999999859342 GO:0097472 cyclin-dependent protein kinase activity 1/1553 29/18639 0.0344827586206897 0.413859715345161 0.919932686394543 0.999999999859342 GO:0046943 carboxylic acid transmembrane transporter activity 11/1553 188/18639 0.0585106382978723 0.702240687208012 0.920707807382575 0.999999999859342 GO:0005254 chloride channel activity 4/1553 83/18639 0.0481927710843374 0.578406349157092 0.92319185212364 0.999999999859342 GO:0030165 PDZ domain binding 4/1553 83/18639 0.0481927710843374 0.578406349157092 0.92319185212364 0.999999999859342 GO:0005342 organic acid transmembrane transporter activity 11/1553 189/18639 0.0582010582010582 0.698525128016435 0.923708383206662 0.999999999859342 GO:0016298 lipase activity 7/1553 130/18639 0.0538461538461538 0.646257863192828 0.923939806135762 0.999999999859342 GO:0032452 histone demethylase activity 1/1553 30/18639 0.0333333333333333 0.400064391500322 0.926614284354203 0.999999999859342 GO:0015293 symporter activity 8/1553 146/18639 0.0547945205479452 0.657640095616968 0.927103598204878 0.999999999859342 GO:0005262 calcium channel activity 7/1553 131/18639 0.0534351145038168 0.641324597061585 0.927362922076304 0.999999999859342 GO:0003730 mRNA 3'-UTR binding 16/1553 262/18639 0.0610687022900763 0.732942396641811 0.928299295189841 0.999999999859342 GO:1990841 promoter-specific chromatin binding 3/1553 68/18639 0.0441176470588235 0.529496988750426 0.930239146310535 0.999999999859342 GO:0016878 acid-thiol ligase activity 1/1553 31/18639 0.032258064516129 0.387159088548699 0.932738633668939 0.999999999859342 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1553 31/18639 0.032258064516129 0.387159088548699 0.932738633668939 0.999999999859342 GO:0140457 protein demethylase activity 1/1553 31/18639 0.032258064516129 0.387159088548699 0.932738633668939 0.999999999859342 GO:0042578 phosphoric ester hydrolase activity 23/1553 363/18639 0.0633608815426997 0.760452975579125 0.935989391708361 0.999999999859342 GO:0042910 xenobiotic transmembrane transporter activity 1/1553 32/18639 0.03125 0.375060367031552 0.938352181708069 0.999999999859342 GO:0070717 poly-purine tract binding 1/1553 32/18639 0.03125 0.375060367031552 0.938352181708069 0.999999999859342 GO:0005544 calcium-dependent phospholipid binding 2/1553 53/18639 0.0377358490566038 0.452903084717346 0.942397733647304 0.999999999859342 GO:0008146 sulfotransferase activity 2/1553 53/18639 0.0377358490566038 0.452903084717346 0.942397733647304 0.999999999859342 GO:0140296 general transcription initiation factor binding 2/1553 53/18639 0.0377358490566038 0.452903084717346 0.942397733647304 0.999999999859342 GO:0019239 deaminase activity 1/1553 33/18639 0.0303030303030303 0.363694901363929 0.943497506682937 0.999999999859342 GO:0004497 monooxygenase activity 5/1553 106/18639 0.0471698113207547 0.566128855896682 0.947029394747209 0.999999999859342 GO:0015020 glucuronosyltransferase activity 1/1553 34/18639 0.0294117647058824 0.352997992500284 0.948213639764814 0.999999999859342 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1553 34/18639 0.0294117647058824 0.352997992500284 0.948213639764814 0.999999999859342 GO:0019825 oxygen binding 1/1553 34/18639 0.0294117647058824 0.352997992500284 0.948213639764814 0.999999999859342 GO:0051427 hormone receptor binding 1/1553 34/18639 0.0294117647058824 0.352997992500284 0.948213639764814 0.999999999859342 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1553 34/18639 0.0294117647058824 0.352997992500284 0.948213639764814 0.999999999859342 GO:0004843 cysteine-type deubiquitinase activity 5/1553 108/18639 0.0462962962962963 0.555644988194892 0.952461987426028 0.999999999859342 GO:0030170 pyridoxal phosphate binding 2/1553 56/18639 0.0357142857142857 0.428640419464631 0.95357870985467 0.999999999859342 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1553 36/18639 0.0277777777777778 0.333386992916935 0.956498467061154 0.999999999859342 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1553 36/18639 0.0277777777777778 0.333386992916935 0.956498467061154 0.999999999859342 GO:0140597 protein carrier chaperone 10/1553 188/18639 0.0531914893617021 0.638400624734556 0.956588315827315 0.999999999859342 GO:0051219 phosphoprotein binding 4/1553 93/18639 0.043010752688172 0.516212118064932 0.956787828532611 0.999999999859342 GO:0070279 vitamin B6 binding 2/1553 57/18639 0.0350877192982456 0.421120412105602 0.956820787529653 0.999999999859342 GO:0140104 molecular carrier activity 14/1553 249/18639 0.0562248995983936 0.674807407349941 0.959286783821001 0.999999999859342 GO:0022829 wide pore channel activity 1/1553 37/18639 0.027027027027027 0.32437653364891 0.960130025447114 0.999999999859342 GO:0003724 RNA helicase activity 3/1553 77/18639 0.038961038961039 0.467607730325052 0.960632570581934 0.999999999859342 GO:0015079 potassium ion transmembrane transporter activity 8/1553 160/18639 0.05 0.600096587250483 0.96152814022524 0.999999999859342 GO:0008194 UDP-glycosyltransferase activity 7/1553 145/18639 0.0482758620689655 0.579403601483225 0.962892791801247 0.999999999859342 GO:0000146 microfilament motor activity 1/1553 38/18639 0.0263157894736842 0.315840309079202 0.96345859605676 0.999999999859342 GO:0042162 telomeric DNA binding 1/1553 38/18639 0.0263157894736842 0.315840309079202 0.96345859605676 0.999999999859342 GO:0008186 ATP-dependent activity, acting on RNA 3/1553 79/18639 0.0379746835443038 0.455769559937076 0.965434149987356 0.999999999859342 GO:0031267 small GTPase binding 16/1553 283/18639 0.0565371024734982 0.678554444947543 0.966016467964857 0.999999999859342 GO:0015085 calcium ion transmembrane transporter activity 7/1553 147/18639 0.0476190476190476 0.571520559286174 0.966417570567061 0.999999999859342 GO:0101005 deubiquitinase activity 5/1553 115/18639 0.0434782608695652 0.521823119348246 0.967713578265431 0.999999999859342 GO:0005249 voltage-gated potassium channel activity 4/1553 98/18639 0.0408163265306122 0.489874765102435 0.967918583464423 0.999999999859342 GO:0061791 GTPase motor activity 1/1553 40/18639 0.025 0.300048293625241 0.969305724272045 0.999999999859342 GO:1990606 membrane scission GTPase motor activity 1/1553 40/18639 0.025 0.300048293625241 0.969305724272045 0.999999999859342 GO:0051020 GTPase binding 18/1553 315/18639 0.0571428571428571 0.685824671143409 0.969485778040012 0.999999999859342 GO:0004812 aminoacyl-tRNA ligase activity 1/1553 41/18639 0.024390243902439 0.292730042561211 0.971868669065072 0.999999999859342 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1553 41/18639 0.024390243902439 0.292730042561211 0.971868669065072 0.999999999859342 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/1553 41/18639 0.024390243902439 0.292730042561211 0.971868669065072 0.999999999859342 GO:0005085 guanyl-nucleotide exchange factor activity 12/1553 230/18639 0.0521739130434783 0.626187743217895 0.973709542842282 0.999999999859342 GO:0019894 kinesin binding 1/1553 42/18639 0.0238095238095238 0.285760279643087 0.974217736542325 0.999999999859342 GO:0035198 miRNA binding 1/1553 42/18639 0.0238095238095238 0.285760279643087 0.974217736542325 0.999999999859342 GO:0005245 voltage-gated calcium channel activity 1/1553 43/18639 0.0232558139534884 0.279114691744411 0.976370764189245 0.999999999859342 GO:0015276 ligand-gated monoatomic ion channel activity 9/1553 186/18639 0.0483870967741935 0.580738632823048 0.976390551068476 0.999999999859342 GO:0022834 ligand-gated channel activity 9/1553 188/18639 0.0478723404255319 0.574560562261101 0.97853912330639 0.999999999859342 GO:0005244 voltage-gated monoatomic ion channel activity 8/1553 173/18639 0.046242774566474 0.555002624046689 0.979565898341326 0.999999999859342 GO:0008081 phosphoric diester hydrolase activity 3/1553 87/18639 0.0344827586206897 0.413859715345161 0.979646496720116 0.999999999859342 GO:0022832 voltage-gated channel activity 8/1553 175/18639 0.0457142857142857 0.548659736914727 0.981517750169251 0.999999999859342 GO:0003727 single-stranded RNA binding 3/1553 89/18639 0.0337078651685393 0.404559497022797 0.982208902322227 0.999999999859342 GO:0005096 GTPase activator activity 14/1553 271/18639 0.0516605166051661 0.620025994207141 0.983209705835264 0.999999999859342 GO:0061749 forked DNA-dependent helicase activity 1/1553 47/18639 0.0212765957446809 0.255360249893823 0.98332971855366 0.999999999859342 GO:0099095 ligand-gated monoatomic anion channel activity 1/1553 47/18639 0.0212765957446809 0.255360249893823 0.98332971855366 0.999999999859342 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1553 47/18639 0.0212765957446809 0.255360249893823 0.98332971855366 0.999999999859342 GO:0019783 ubiquitin-like protein peptidase activity 5/1553 127/18639 0.0393700787401575 0.472516997835026 0.983805584213947 0.999999999859342 GO:0009378 four-way junction helicase activity 1/1553 48/18639 0.0208333333333333 0.250040244687701 0.984722196344439 0.999999999859342 GO:0032266 phosphatidylinositol-3-phosphate binding 1/1553 48/18639 0.0208333333333333 0.250040244687701 0.984722196344439 0.999999999859342 GO:0036121 double-stranded DNA helicase activity 1/1553 48/18639 0.0208333333333333 0.250040244687701 0.984722196344439 0.999999999859342 GO:0043138 3'-5' DNA helicase activity 1/1553 48/18639 0.0208333333333333 0.250040244687701 0.984722196344439 0.999999999859342 GO:0140693 molecular condensate scaffold activity 1/1553 48/18639 0.0208333333333333 0.250040244687701 0.984722196344439 0.999999999859342 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 12/1553 243/18639 0.0493827160493827 0.592687987407884 0.985105462736153 0.999999999859342 GO:0016758 hexosyltransferase activity 9/1553 197/18639 0.0456852791878173 0.548311602563893 0.986159797888108 0.999999999859342 GO:0004676 3-phosphoinositide-dependent protein kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0004711 ribosomal protein S6 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0035175 histone H3S10 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0035979 histone H2AXS139 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0044022 histone H3S28 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0044023 histone H4S1 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0044024 histone H2AS1 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0044025 histone H2BS14 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0072354 histone H3T3 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0072371 histone H2AS121 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0072518 Rho-dependent protein serine/threonine kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0140823 histone H2BS36 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0140855 histone H3S57 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0140995 histone H2A kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0140997 histone H4 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0140998 histone H2B kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:1990244 histone H2AT120 kinase activity 12/1553 245/18639 0.0489795918367347 0.587849718122922 0.986386345055025 0.999999999859342 GO:0004677 DNA-dependent protein kinase activity 12/1553 246/18639 0.0487804878048781 0.585460085122422 0.986988012049324 0.999999999859342 GO:0140857 histone H3T45 kinase activity 12/1553 246/18639 0.0487804878048781 0.585460085122422 0.986988012049324 0.999999999859342 GO:0035402 histone H3T11 kinase activity 12/1553 247/18639 0.048582995951417 0.583089801376988 0.987565073831206 0.999999999859342 GO:0035403 histone H3T6 kinase activity 12/1553 247/18639 0.048582995951417 0.583089801376988 0.987565073831206 0.999999999859342 GO:0035064 methylated histone binding 2/1553 74/18639 0.027027027027027 0.32437653364891 0.987754971456587 0.999999999859342 GO:0004679 AMP-activated protein kinase activity 12/1553 248/18639 0.0483870967741935 0.580738632823048 0.988118429015425 0.999999999859342 GO:0005272 sodium channel activity 1/1553 51/18639 0.0196078431372549 0.235331995000189 0.988240140718664 0.999999999859342 GO:0140034 methylation-dependent protein binding 2/1553 76/18639 0.0263157894736842 0.315840309079202 0.98947483879275 0.999999999859342 GO:0030594 neurotransmitter receptor activity 3/1553 97/18639 0.0309278350515464 0.371193765309577 0.989693224536593 0.999999999859342 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1553 53/18639 0.0188679245283019 0.226451542358673 0.990123138972531 0.999999999859342 GO:0106310 protein serine kinase activity 19/1553 361/18639 0.0526315789473684 0.631680618158403 0.990682886708079 0.999999999859342 GO:0140463 chromatin-protein adaptor activity 1/1553 54/18639 0.0185185185185185 0.222257995277957 0.990948424949915 0.999999999859342 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1553 56/18639 0.0178571428571429 0.214320209732315 0.992397994283934 0.999999999859342 GO:0140658 ATP-dependent chromatin remodeler activity 6/1553 158/18639 0.0379746835443038 0.455769559937076 0.992587184990448 0.999999999859342 GO:0030971 receptor tyrosine kinase binding 2/1553 81/18639 0.0246913580246914 0.296343993703942 0.99280746870616 0.999999999859342 GO:0141003 histone H2AX kinase activity 18/1553 354/18639 0.0508474576271186 0.610267715847949 0.993304826971064 0.999999999859342 GO:0030695 GTPase regulator activity 27/1553 489/18639 0.0552147239263804 0.662683347883969 0.993480337771934 0.999999999859342 GO:0017116 single-stranded DNA helicase activity 1/1553 58/18639 0.0172413793103448 0.20692985767258 0.993615546876049 0.999999999859342 GO:0061980 regulatory RNA binding 1/1553 58/18639 0.0172413793103448 0.20692985767258 0.993615546876049 0.999999999859342 GO:0060589 nucleoside-triphosphatase regulator activity 27/1553 490/18639 0.0551020408163265 0.661330932888287 0.993711436462433 0.999999999859342 GO:0022843 voltage-gated monoatomic cation channel activity 5/1553 143/18639 0.034965034965035 0.419647963112226 0.993830066120952 0.999999999859342 GO:0140996 histone H3 kinase activity 18/1553 357/18639 0.0504201680672269 0.605139415714773 0.994091491809389 0.999999999859342 GO:0015081 sodium ion transmembrane transporter activity 6/1553 164/18639 0.0365853658536585 0.439095063841817 0.994788239546844 0.999999999859342 GO:0035173 histone kinase activity 18/1553 360/18639 0.05 0.600096587250483 0.994791500098329 0.999999999859342 GO:0016755 aminoacyltransferase activity 27/1553 496/18639 0.0544354838709677 0.653330961925929 0.994946636245247 0.999999999859342 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/1553 86/18639 0.0232558139534884 0.279114691744411 0.995099989884701 0.999999999859342 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1553 63/18639 0.0158730158730159 0.190506853095391 0.995873563435921 0.999999999859342 GO:0022835 transmitter-gated channel activity 1/1553 63/18639 0.0158730158730159 0.190506853095391 0.995873563435921 0.999999999859342 GO:0000510 H3-H4 histone complex chaperone activity 5/1553 151/18639 0.033112582781457 0.397414958444028 0.996254236647937 0.999999999859342 GO:0140584 chromatin extrusion motor activity 5/1553 151/18639 0.033112582781457 0.397414958444028 0.996254236647937 0.999999999859342 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/1553 151/18639 0.033112582781457 0.397414958444028 0.996254236647937 0.999999999859342 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/1553 151/18639 0.033112582781457 0.397414958444028 0.996254236647937 0.999999999859342 GO:0015616 DNA translocase activity 5/1553 152/18639 0.0328947368421053 0.394800386349002 0.996483240278766 0.999999999859342 GO:0140674 ATP-dependent histone chaperone activity 5/1553 152/18639 0.0328947368421053 0.394800386349002 0.996483240278766 0.999999999859342 GO:0015631 tubulin binding 19/1553 385/18639 0.0493506493506494 0.592303125078399 0.996530347254611 0.999999999859342 GO:0003774 cytoskeletal motor activity 5/1553 153/18639 0.0326797385620915 0.392219991666982 0.996698739431712 0.999999999859342 GO:0061775 cohesin loader activity 5/1553 153/18639 0.0326797385620915 0.392219991666982 0.996698739431712 0.999999999859342 GO:0016887 ATP hydrolysis activity 21/1553 417/18639 0.0503597122302158 0.604413828885379 0.996707366914168 0.999999999859342 GO:0019787 ubiquitin-like protein transferase activity 25/1553 479/18639 0.0521920668058455 0.626405623434742 0.996883809186714 0.999999999859342 GO:0004842 ubiquitin-protein transferase activity 23/1553 449/18639 0.0512249443207127 0.614798285379114 0.996907278219839 0.999999999859342 GO:0046873 metal ion transmembrane transporter activity 23/1553 450/18639 0.0511111111111111 0.61343206696716 0.997029309942305 0.999999999859342 GO:0003823 antigen binding 6/1553 174/18639 0.0344827586206897 0.413859715345161 0.997139369761693 0.999999999859342 GO:0003777 microtubule motor activity 1/1553 68/18639 0.0147058823529412 0.176498996250142 0.99733330513665 0.999999999859342 GO:0005548 phospholipid transporter activity 1/1553 68/18639 0.0147058823529412 0.176498996250142 0.99733330513665 0.999999999859342 GO:1990782 protein tyrosine kinase binding 3/1553 117/18639 0.0256410256410256 0.307741839615632 0.997483869184715 0.999999999859342 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1553 69/18639 0.0144927536231884 0.173941039782749 0.997556307512547 0.999999999859342 GO:0003689 DNA clamp loader activity 5/1553 160/18639 0.03125 0.375060367031552 0.997888105177926 0.999999999859342 GO:0140097 catalytic activity, acting on DNA 15/1553 336/18639 0.0446428571428571 0.535800524330788 0.998172090625647 0.999999999859342 GO:0061630 ubiquitin protein ligase activity 16/1553 353/18639 0.0453257790368272 0.54399690628939 0.998244933174997 0.999999999859342 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1553 73/18639 0.0136986301369863 0.164410023904242 0.998276869671149 0.999999999859342 GO:0140713 histone chaperone activity 5/1553 164/18639 0.0304878048780488 0.365912553201514 0.998368896106829 0.999999999859342 GO:0003678 DNA helicase activity 1/1553 74/18639 0.0135135135135135 0.162188266824455 0.998421005263129 0.999999999859342 GO:0061659 ubiquitin-like protein ligase activity 17/1553 372/18639 0.0456989247311828 0.54847537544399 0.998470514228224 0.999999999859342 GO:0008017 microtubule binding 11/1553 276/18639 0.0398550724637681 0.478337859402559 0.998678900632651 0.999999999859342 GO:0008094 ATP-dependent activity, acting on DNA 7/1553 210/18639 0.0333333333333333 0.400064391500322 0.999009373059424 0.999999999859342 GO:1902936 phosphatidylinositol bisphosphate binding 2/1553 111/18639 0.018018018018018 0.216251022432606 0.999307144592937 0.999999999859342 GO:0022836 gated channel activity 12/1553 318/18639 0.0377358490566038 0.452903084717346 0.99965090049353 0.999999999859342 GO:0042393 histone binding 8/1553 247/18639 0.0323886639676113 0.388726534251325 0.999674065498072 0.999999999859342 GO:0004386 helicase activity 3/1553 155/18639 0.0193548387096774 0.232295453129219 0.999848259097607 0.999999999859342 GO:0001216 DNA-binding transcription activator activity 21/1553 491/18639 0.0427698574338086 0.513320909664364 0.999881889324882 0.999999999859342 GO:1901981 phosphatidylinositol phosphate binding 4/1553 185/18639 0.0216216216216216 0.259501226919128 0.999909085182344 0.999999999859342 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 20/1553 484/18639 0.0413223140495868 0.495947592768994 0.999926024037325 0.999999999859342 GO:0035091 phosphatidylinositol binding 5/1553 284/18639 0.0176056338028169 0.211301615229043 0.999999654469541 0.999999999859342 GO:0045182 translation regulator activity 5/1553 356/18639 0.0140449438202247 0.168566457092832 0.999999998569103 0.999999999859342 GO:0030371 translation repressor activity 3/1553 329/18639 0.00911854103343465 0.109440107097353 0.999999999859342 0.999999999859342