ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0022853	active monoatomic ion transmembrane transporter activity	29/562	118/18639	0.245762711864407	8.15083841003679	1.02495539813011e-18	8.17914407707828e-16
GO:0015078	proton transmembrane transporter activity	35/562	185/18639	0.189189189189189	6.27455035106281	2.19376596266032e-18	8.75312619101469e-16
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	22/562	68/18639	0.323529411764706	10.7300083734561	2.57355117908109e-17	6.8456461363557e-15
GO:0009055	electron transfer activity	25/562	116/18639	0.21551724137931	7.14773285065652	7.10261664664308e-15	1.41697202100529e-12
GO:0015399	primary active transmembrane transporter activity	29/562	166/18639	0.174698795180723	5.79396947219483	1.68142061633859e-14	2.68354730367639e-12
GO:0008137	NADH dehydrogenase (ubiquinone) activity	14/562	41/18639	0.341463414634146	11.3247981946012	7.28596005552276e-12	9.69032687384527e-10
GO:0003954	NADH dehydrogenase activity	14/562	44/18639	0.318181818181818	10.5526528631511	2.18667761438184e-11	2.49281248039529e-09
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	15/562	58/18639	0.258620689655172	8.57727942078783	1.15648426360284e-10	1.15359305294384e-08
GO:0016651	oxidoreductase activity, acting on NAD(P)H	16/562	88/18639	0.181818181818182	6.03008735037205	7.33977487975782e-09	6.5079337267186e-07
GO:0004129	cytochrome-c oxidase activity	7/562	15/18639	0.466666666666667	15.4772241992883	1.13844016071184e-07	9.0847524824805e-06
GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/562	16/18639	0.4375	14.5098976868327	1.97130505352689e-07	1.4300922115586e-05
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	7/562	18/18639	0.388888888888889	12.8976868327402	5.20269830788925e-07	3.45979437474635e-05
GO:0022804	active transmembrane transporter activity	34/562	457/18639	0.074398249452954	2.46745368603845	1.34175110812356e-06	8.23628757140461e-05
GO:0004857	enzyme inhibitor activity	30/562	416/18639	0.0721153846153846	2.39174137695045	1.03715477524802e-05	0.000591178221891374
GO:0015252	proton channel activity	7/562	27/18639	0.259259259259259	8.59845788849348	1.14628015259805e-05	0.000609821041182161
GO:0044548	S100 protein binding	5/562	14/18639	0.357142857142857	11.8448144382308	3.91018943371882e-05	0.00195020698006726
GO:0030414	peptidase inhibitor activity	16/562	169/18639	0.0946745562130177	3.13992714102213	5.44005220140543e-05	0.00235382416704615
GO:0005518	collagen binding	10/562	72/18639	0.138888888888889	4.60631672597865	5.72617447831064e-05	0.00235382416704615
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/562	24/18639	0.25	8.29137010676157	6.19427412380565e-05	0.00235382416704615
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/562	24/18639	0.25	8.29137010676157	6.19427412380565e-05	0.00235382416704615
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/562	24/18639	0.25	8.29137010676157	6.19427412380565e-05	0.00235382416704615
GO:0004866	endopeptidase inhibitor activity	15/562	161/18639	0.093167701863354	3.08995159258195	0.000110688659699439	0.00401497956546148
GO:0023026	MHC class II protein complex binding	6/562	27/18639	0.222222222222222	7.37010676156584	0.000126138943798516	0.00437647291961807
GO:0061135	endopeptidase regulator activity	16/562	184/18639	0.0869565217391304	2.88395481974315	0.000149014624276692	0.00495473625719999
GO:0061134	peptidase regulator activity	17/562	226/18639	0.0752212389380531	2.49474852769817	0.000522199115029771	0.0166685957517503
GO:0005201	extracellular matrix structural constituent	14/562	168/18639	0.0833333333333333	2.76379003558719	0.000583412334047425	0.017906270868071
GO:0008191	metalloendopeptidase inhibitor activity	4/562	14/18639	0.285714285714286	9.47585155058465	0.000643216995788724	0.0183316843799786
GO:0032036	myosin heavy chain binding	4/562	14/18639	0.285714285714286	9.47585155058465	0.000643216995788724	0.0183316843799786
GO:0023023	MHC protein complex binding	6/562	37/18639	0.162162162162162	5.37818601519669	0.000767289690886357	0.0209731449626954
GO:0019211	phosphatase activator activity	5/562	25/18639	0.2	6.63309608540925	0.000788464096341931	0.0209731449626954
GO:0031386	protein tag activity	4/562	15/18639	0.266666666666667	8.844128113879	0.00085631371403985	0.0213543232438688
GO:0141047	molecular tag activity	4/562	15/18639	0.266666666666667	8.844128113879	0.00085631371403985	0.0213543232438688
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	7/562	54/18639	0.12962962962963	4.29922894424674	0.0011315913417844	0.0273639360831501
GO:0045499	chemorepellent activity	5/562	28/18639	0.178571428571429	5.9224072191154	0.00135377901594013	0.0317739898447125
GO:0048306	calcium-dependent protein binding	8/562	80/18639	0.1	3.31654804270463	0.00280536609936552	0.0624280767210246
GO:0043021	ribonucleoprotein complex binding	13/562	177/18639	0.0734463276836158	2.43588274322939	0.00281630421297855	0.0624280767210246
GO:0072542	protein phosphatase activator activity	4/562	21/18639	0.19047619047619	6.31723436705643	0.00325281184554502	0.0701552392633764
GO:0005178	integrin binding	12/562	161/18639	0.0745341614906832	2.47196127406556	0.00357581851862329	0.0749003163967779
GO:0010854	adenylate cyclase regulator activity	3/562	11/18639	0.272727272727273	9.04513102555807	0.00375440182439989	0.0749003163967779
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/562	11/18639	0.272727272727273	9.04513102555807	0.00375440182439989	0.0749003163967779
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/562	22/18639	0.181818181818182	6.03008735037205	0.00388207918371707	0.0755002624413271
GO:0050840	extracellular matrix binding	7/562	67/18639	0.104477611940299	3.4650501938705	0.00397369802322774	0.0755002624413271
GO:0003779	actin binding	24/562	443/18639	0.054176072234763	1.79677546331628	0.0043132793299236	0.0778772203091597
GO:0032934	sterol binding	7/562	68/18639	0.102941176470588	3.41409357337241	0.00431731407928563	0.0778772203091597
GO:0016209	antioxidant activity	8/562	86/18639	0.0930232558139535	3.08516096995779	0.00439157257382479	0.0778772203091597
GO:0010853	cyclase activator activity	3/562	12/18639	0.25	8.29137010676157	0.00489462254156768	0.0849110606124132
GO:0005496	steroid binding	9/562	108/18639	0.0833333333333333	2.76379003558719	0.00537688506561085	0.0884311501549628
GO:0030215	semaphorin receptor binding	4/562	24/18639	0.166666666666667	5.52758007117438	0.00537730706446261	0.0884311501549628
GO:0015485	cholesterol binding	6/562	54/18639	0.111111111111111	3.68505338078292	0.0055407988818899	0.0884311501549628
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/562	54/18639	0.111111111111111	3.68505338078292	0.0055407988818899	0.0884311501549628
GO:0043178	alcohol binding	8/562	92/18639	0.0869565217391304	2.88395481974315	0.00659123111292483	0.10238817566523
GO:0015036	disulfide oxidoreductase activity	5/562	40/18639	0.125	4.14568505338078	0.00674000988193106	0.10238817566523
GO:0043022	ribosome binding	9/562	112/18639	0.0803571428571429	2.66508324860193	0.0068002171807734	0.10238817566523
GO:0019003	GDP binding	7/562	75/18639	0.0933333333333333	3.09544483985765	0.00738690908891692	0.109162100980661
GO:0016530	metallochaperone activity	3/562	14/18639	0.214285714285714	7.10688866293849	0.00774326418259953	0.112347723958444
GO:0031625	ubiquitin protein ligase binding	17/562	302/18639	0.0562913907284768	1.86693101741651	0.0104869862504075	0.149439554068307
GO:0008009	chemokine activity	5/562	45/18639	0.111111111111111	3.68505338078292	0.0110711688363653	0.154081541229645
GO:0005159	insulin-like growth factor receptor binding	3/562	16/18639	0.1875	6.21852758007117	0.0113919936498109	0.154081541229645
GO:0055102	lipase inhibitor activity	3/562	16/18639	0.1875	6.21852758007117	0.0113919936498109	0.154081541229645
GO:0001968	fibronectin binding	4/562	30/18639	0.133333333333333	4.4220640569395	0.0120320493708246	0.160026256631967
GO:0051117	ATPase binding	7/562	84/18639	0.0833333333333333	2.76379003558719	0.0133969261336303	0.16356781437416
GO:0070325	lipoprotein particle receptor binding	4/562	31/18639	0.129032258064516	4.27941682929629	0.0134926773632342	0.16356781437416
GO:0008429	phosphatidylethanolamine binding	3/562	17/18639	0.176470588235294	5.85273184006699	0.0135281650986147	0.16356781437416
GO:0038191	neuropilin binding	3/562	17/18639	0.176470588235294	5.85273184006699	0.0135281650986147	0.16356781437416
GO:0051787	misfolded protein binding	3/562	17/18639	0.176470588235294	5.85273184006699	0.0135281650986147	0.16356781437416
GO:0070492	oligosaccharide binding	3/562	17/18639	0.176470588235294	5.85273184006699	0.0135281650986147	0.16356781437416
GO:0035254	glutamate receptor binding	5/562	49/18639	0.102040816326531	3.38423269663737	0.0156719808374316	0.186315225436573
GO:0098641	cadherin binding involved in cell-cell adhesion	3/562	18/18639	0.166666666666667	5.52758007117438	0.0158764853755475	0.186315225436573
GO:0004197	cysteine-type endopeptidase activity	7/562	88/18639	0.0795454545454545	2.63816321578777	0.0169610811556025	0.196158590756099
GO:0005520	insulin-like growth factor binding	3/562	19/18639	0.157894736842105	5.23665480427046	0.0184390373838825	0.203586027494547
GO:0015035	protein-disulfide reductase activity	4/562	34/18639	0.117647058823529	3.90182122671133	0.0185318101305924	0.203586027494547
GO:0001664	G protein-coupled receptor binding	16/562	297/18639	0.0538720538720539	1.78669254825838	0.0186103515125031	0.203586027494547
GO:0044389	ubiquitin-like protein ligase binding	17/562	322/18639	0.0527950310559006	1.75097256912977	0.0186237844700526	0.203586027494547
GO:0042277	peptide binding	14/562	249/18639	0.0562248995983936	1.86472580714316	0.0192450405055886	0.207534355722429
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/562	20/18639	0.15	4.97482206405694	0.021217083711766	0.219886140285575
GO:0010851	cyclase regulator activity	3/562	20/18639	0.15	4.97482206405694	0.021217083711766	0.219886140285575
GO:0043024	ribosomal small subunit binding	3/562	20/18639	0.15	4.97482206405694	0.021217083711766	0.219886140285575
GO:0019887	protein kinase regulator activity	14/562	255/18639	0.0549019607843137	1.82084990579862	0.0230660034675237	0.235982958552358
GO:0043394	proteoglycan binding	4/562	37/18639	0.108108108108108	3.58545734346446	0.0245996264728744	0.246618474079152
GO:0004867	serine-type endopeptidase inhibitor activity	7/562	95/18639	0.0736842105263158	2.44377224199288	0.0247236565492884	0.246618474079152
GO:0019208	phosphatase regulator activity	8/562	117/18639	0.0683760683760684	2.26772515740487	0.0253333328057106	0.248606611348804
GO:0044183	protein folding chaperone	6/562	75/18639	0.08	2.6532384341637	0.0255460427701779	0.248606611348804
GO:0017022	myosin binding	6/562	76/18639	0.0789473684210526	2.61832740213523	0.0270559221650072	0.254441177208389
GO:0098631	cell adhesion mediator activity	6/562	76/18639	0.0789473684210526	2.61832740213523	0.0270559221650072	0.254441177208389
GO:0034062	5'-3' RNA polymerase activity	3/562	22/18639	0.136363636363636	4.52256551277904	0.0274209789973953	0.254441177208389
GO:0097747	RNA polymerase activity	3/562	22/18639	0.136363636363636	4.52256551277904	0.0274209789973953	0.254441177208389
GO:0004601	peroxidase activity	5/562	57/18639	0.087719298245614	2.90925266903915	0.0283374509393645	0.259922825857619
GO:0042626	ATPase-coupled transmembrane transporter activity	7/562	98/18639	0.0714285714285714	2.36896288764616	0.0286939955934633	0.260202369131633
GO:0005212	structural constituent of eye lens	3/562	23/18639	0.130434782608696	4.32593222961473	0.0308457959886028	0.273499391098945
GO:0005283	amino acid:sodium symporter activity	3/562	23/18639	0.130434782608696	4.32593222961473	0.0308457959886028	0.273499391098945
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	5/562	59/18639	0.0847457627118644	2.81063393449545	0.0322835997322187	0.283102336113303
GO:0001530	lipopolysaccharide binding	4/562	41/18639	0.0975609756097561	3.2356566270289	0.0343580562943002	0.292210089426703
GO:0017080	sodium channel regulator activity	4/562	41/18639	0.0975609756097561	3.2356566270289	0.0343580562943002	0.292210089426703
GO:0016783	sulfurtransferase activity	2/562	10/18639	0.2	6.63309608540925	0.0347869154079408	0.292210089426703
GO:0030957	Tat protein binding	2/562	10/18639	0.2	6.63309608540925	0.0347869154079408	0.292210089426703
GO:0048487	beta-tubulin binding	4/562	42/18639	0.0952380952380952	3.15861718352822	0.0371014219025853	0.308405569565241
GO:0120020	cholesterol transfer activity	3/562	25/18639	0.12	3.97985765124555	0.0383340759797585	0.315366934348941
GO:0001540	amyloid-beta binding	6/562	83/18639	0.072289156626506	2.39750460918407	0.0392849160668917	0.316165400213869
GO:0003735	structural constituent of ribosome	10/562	175/18639	0.0571428571428571	1.89517031011693	0.0397188245216552	0.316165400213869
GO:0000099	sulfur amino acid transmembrane transporter activity	2/562	11/18639	0.181818181818182	6.03008735037205	0.0416830295376166	0.316165400213869
GO:0008199	ferric iron binding	2/562	11/18639	0.181818181818182	6.03008735037205	0.0416830295376166	0.316165400213869
GO:0019206	nucleoside kinase activity	2/562	11/18639	0.181818181818182	6.03008735037205	0.0416830295376166	0.316165400213869
GO:0050998	nitric-oxide synthase binding	2/562	11/18639	0.181818181818182	6.03008735037205	0.0416830295376166	0.316165400213869
GO:0070990	snRNP binding	2/562	11/18639	0.181818181818182	6.03008735037205	0.0416830295376166	0.316165400213869
GO:0097493	structural molecule activity conferring elasticity	2/562	11/18639	0.181818181818182	6.03008735037205	0.0416830295376166	0.316165400213869
GO:0008198	ferrous iron binding	3/562	26/18639	0.115384615384615	3.82678620312072	0.042393105041208	0.316165400213869
GO:0097602	cullin family protein binding	3/562	26/18639	0.115384615384615	3.82678620312072	0.042393105041208	0.316165400213869
GO:0003924	GTPase activity	16/562	331/18639	0.0483383685800604	1.60316521701734	0.0439433525077798	0.324692549085262
GO:0042605	peptide antigen binding	4/562	45/18639	0.0888888888888889	2.94804270462633	0.0460660654556451	0.334440245957243
GO:0019843	rRNA binding	5/562	65/18639	0.0769230769230769	2.55119080208048	0.0461007857835798	0.334440245957243
GO:0008320	protein transmembrane transporter activity	3/562	27/18639	0.111111111111111	3.68505338078292	0.0466583239687511	0.335435518261832
GO:0004859	phospholipase inhibitor activity	2/562	12/18639	0.166666666666667	5.52758007117438	0.0490407109368264	0.343284976557785
GO:0008179	adenylate cyclase binding	2/562	12/18639	0.166666666666667	5.52758007117438	0.0490407109368264	0.343284976557785
GO:0035259	nuclear glucocorticoid receptor binding	2/562	12/18639	0.166666666666667	5.52758007117438	0.0490407109368264	0.343284976557785
GO:0051537	2 iron, 2 sulfur cluster binding	3/562	28/18639	0.107142857142857	3.55344433146924	0.0511264089183993	0.354772820146806
GO:0005125	cytokine activity	12/562	234/18639	0.0512820512820513	1.70079386805365	0.0519654437836954	0.357486414994732
GO:0019207	kinase regulator activity	14/562	287/18639	0.0487804878048781	1.61782831351445	0.0534909307962674	0.364187517650759
GO:0002020	protease binding	8/562	136/18639	0.0588235294117647	1.95091061335566	0.0538522895774305	0.364187517650759
GO:0005416	amino acid:monoatomic cation symporter activity	3/562	29/18639	0.103448275862069	3.43091176831513	0.0557936659713197	0.367592404342686
GO:0043236	laminin binding	3/562	29/18639	0.103448275862069	3.43091176831513	0.0557936659713197	0.367592404342686
GO:0019855	calcium channel inhibitor activity	2/562	13/18639	0.153846153846154	5.10238160416096	0.0568259628344837	0.367592404342686
GO:0031432	titin binding	2/562	13/18639	0.153846153846154	5.10238160416096	0.0568259628344837	0.367592404342686
GO:0031994	insulin-like growth factor I binding	2/562	13/18639	0.153846153846154	5.10238160416096	0.0568259628344837	0.367592404342686
GO:0008083	growth factor activity	9/562	162/18639	0.0555555555555556	1.84252669039146	0.0571196217274349	0.367592404342686
GO:0030295	protein kinase activator activity	8/562	139/18639	0.0575539568345324	1.90880462889475	0.059703320288239	0.381145996720118
GO:0001965	G-protein alpha-subunit binding	3/562	30/18639	0.1	3.31654804270463	0.0606560678158191	0.384155096166854
GO:0048020	CCR chemokine receptor binding	4/562	50/18639	0.08	2.6532384341637	0.0634411954046712	0.398630503408879
GO:0005161	platelet-derived growth factor receptor binding	2/562	14/18639	0.142857142857143	4.73792577529232	0.0650064126097977	0.399039363558604
GO:0005313	L-glutamate transmembrane transporter activity	2/562	14/18639	0.142857142857143	4.73792577529232	0.0650064126097977	0.399039363558604
GO:0043176	amine binding	2/562	14/18639	0.142857142857143	4.73792577529232	0.0650064126097977	0.399039363558604
GO:0042379	chemokine receptor binding	5/562	72/18639	0.0694444444444444	2.30315836298932	0.0660537007079719	0.40218503947565
GO:0016874	ligase activity	9/562	167/18639	0.0538922155688623	1.78736122061926	0.0665268486350699	0.40218503947565
GO:0043539	protein serine/threonine kinase activator activity	5/562	73/18639	0.0684931506849315	2.27160824842783	0.0692416993990599	0.415450196394359
GO:0022884	macromolecule transmembrane transporter activity	3/562	32/18639	0.09375	3.10926379003559	0.0709487344146738	0.419385852317849
GO:0120015	sterol transfer activity	3/562	32/18639	0.09375	3.10926379003559	0.0709487344146738	0.419385852317849
GO:0005523	tropomyosin binding	2/562	15/18639	0.133333333333333	4.4220640569395	0.0735512450421144	0.419585763086526
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/562	15/18639	0.133333333333333	4.4220640569395	0.0735512450421144	0.419585763086526
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/562	15/18639	0.133333333333333	4.4220640569395	0.0735512450421144	0.419585763086526
GO:0140776	protein-containing complex destabilizing activity	2/562	15/18639	0.133333333333333	4.4220640569395	0.0735512450421144	0.419585763086526
GO:0051082	unfolded protein binding	7/562	121/18639	0.0578512396694215	1.91866415693656	0.073611537383601	0.419585763086526
GO:0019209	kinase activator activity	8/562	148/18639	0.0540540540540541	1.79272867173223	0.079579720186624	0.450387352545574
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/562	16/18639	0.125	4.14568505338078	0.0824311380981577	0.456805890293957
GO:0019841	retinol binding	2/562	16/18639	0.125	4.14568505338078	0.0824311380981577	0.456805890293957
GO:0034450	ubiquitin-ubiquitin ligase activity	2/562	16/18639	0.125	4.14568505338078	0.0824311380981577	0.456805890293957
GO:0098632	cell-cell adhesion mediator activity	4/562	55/18639	0.0727272727272727	2.41203494014882	0.0837723302920033	0.461036686710473
GO:0005343	organic acid:sodium symporter activity	3/562	35/18639	0.0857142857142857	2.84275546517539	0.0877351266915476	0.477860079655453
GO:0008238	exopeptidase activity	6/562	102/18639	0.0588235294117647	1.95091061335566	0.088026856778636	0.477860079655453
GO:0004550	nucleoside diphosphate kinase activity	2/562	17/18639	0.117647058823529	3.90182122671133	0.0916182011647634	0.487408830196542
GO:0032977	membrane insertase activity	2/562	17/18639	0.117647058823529	3.90182122671133	0.0916182011647634	0.487408830196542
GO:0048038	quinone binding	2/562	17/18639	0.117647058823529	3.90182122671133	0.0916182011647634	0.487408830196542
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/562	36/18639	0.0833333333333333	2.76379003558719	0.0936692416874701	0.488549378213079
GO:0045505	dynein intermediate chain binding	3/562	36/18639	0.0833333333333333	2.76379003558719	0.0936692416874701	0.488549378213079
GO:0055106	ubiquitin-protein transferase regulator activity	3/562	36/18639	0.0833333333333333	2.76379003558719	0.0936692416874701	0.488549378213079
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	7/562	130/18639	0.0538461538461538	1.78583356145634	0.0985515811402847	0.507336859619217
GO:0015172	acidic amino acid transmembrane transporter activity	2/562	18/18639	0.111111111111111	3.68505338078292	0.101085915638415	0.507336859619217
GO:0031690	adrenergic receptor binding	2/562	18/18639	0.111111111111111	3.68505338078292	0.101085915638415	0.507336859619217
GO:0050811	GABA receptor binding	2/562	18/18639	0.111111111111111	3.68505338078292	0.101085915638415	0.507336859619217
GO:0070064	proline-rich region binding	2/562	18/18639	0.111111111111111	3.68505338078292	0.101085915638415	0.507336859619217
GO:1990381	ubiquitin-specific protease binding	2/562	18/18639	0.111111111111111	3.68505338078292	0.101085915638415	0.507336859619217
GO:0019888	protein phosphatase regulator activity	6/562	107/18639	0.0560747663551402	1.85974656600259	0.104666620115702	0.519006682047848
GO:0005109	frizzled binding	3/562	38/18639	0.0789473684210526	2.61832740213523	0.106012643074936	0.519006682047848
GO:0005501	retinoid binding	3/562	38/18639	0.0789473684210526	2.61832740213523	0.106012643074936	0.519006682047848
GO:0019840	isoprenoid binding	3/562	38/18639	0.0789473684210526	2.61832740213523	0.106012643074936	0.519006682047848
GO:0004175	endopeptidase activity	17/562	405/18639	0.0419753086419753	1.39213127718466	0.107384573586139	0.522517620254503
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	15/562	349/18639	0.0429799426934097	1.42545044815385	0.108122225798132	0.522918401132785
GO:0004860	protein kinase inhibitor activity	5/562	84/18639	0.0595238095238095	1.97413573970513	0.109699023162684	0.524238760492574
GO:0005525	GTP binding	16/562	378/18639	0.0423280423280423	1.40382985934587	0.10970911403792	0.524238760492574
GO:0016918	retinal binding	2/562	19/18639	0.105263157894737	3.49110320284698	0.110809077786007	0.526343119483535
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/562	39/18639	0.0769230769230769	2.55119080208048	0.112410604902741	0.530790903623594
GO:0016004	phospholipase activator activity	2/562	20/18639	0.1	3.31654804270463	0.120763743794257	0.563564137706531
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/562	20/18639	0.1	3.31654804270463	0.120763743794257	0.563564137706531
GO:0005507	copper ion binding	4/562	63/18639	0.0634920634920635	2.10574478901881	0.121984413940374	0.565950943746619
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/562	41/18639	0.0731707317073171	2.42674247027168	0.125630173616102	0.569618628100281
GO:0042287	MHC protein binding	3/562	41/18639	0.0731707317073171	2.42674247027168	0.125630173616102	0.569618628100281
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/562	41/18639	0.0731707317073171	2.42674247027168	0.125630173616102	0.569618628100281
GO:0140318	protein transporter activity	3/562	41/18639	0.0731707317073171	2.42674247027168	0.125630173616102	0.569618628100281
GO:0005126	cytokine receptor binding	12/562	275/18639	0.0436363636363636	1.44722096408929	0.129173354629696	0.580443817714549
GO:0008373	sialyltransferase activity	2/562	21/18639	0.0952380952380952	3.15861718352822	0.130927176928094	0.580443817714549
GO:0010314	phosphatidylinositol-5-phosphate binding	2/562	21/18639	0.0952380952380952	3.15861718352822	0.130927176928094	0.580443817714549
GO:0019200	carbohydrate kinase activity	2/562	21/18639	0.0952380952380952	3.15861718352822	0.130927176928094	0.580443817714549
GO:0019210	kinase inhibitor activity	5/562	90/18639	0.0555555555555556	1.84252669039146	0.135676173587911	0.598174511177641
GO:0008235	metalloexopeptidase activity	4/562	66/18639	0.0606060606060606	2.01002911679068	0.137938009893527	0.604805120302389
GO:0048156	tau protein binding	3/562	43/18639	0.0697674418604651	2.31387072746834	0.139375545699255	0.60776877304921
GO:0031683	G-protein beta/gamma-subunit complex binding	2/562	22/18639	0.0909090909090909	3.01504367518602	0.141277796721164	0.609403685316154
GO:0070034	telomerase RNA binding	2/562	22/18639	0.0909090909090909	3.01504367518602	0.141277796721164	0.609403685316154
GO:0019955	cytokine binding	7/562	144/18639	0.0486111111111111	1.61221085409253	0.145346547840744	0.621551493758692
GO:0019205	nucleobase-containing compound kinase activity	3/562	44/18639	0.0681818181818182	2.26128275638952	0.146430677727612	0.621551493758692
GO:0030547	signaling receptor inhibitor activity	3/562	44/18639	0.0681818181818182	2.26128275638952	0.146430677727612	0.621551493758692
GO:0140223	general transcription initiation factor activity	4/562	68/18639	0.0588235294117647	1.95091061335566	0.149014461333906	0.629172170076493
GO:0003887	DNA-directed DNA polymerase activity	2/562	23/18639	0.0869565217391304	2.88395481974315	0.151795130124265	0.630898509578975
GO:0004602	glutathione peroxidase activity	2/562	23/18639	0.0869565217391304	2.88395481974315	0.151795130124265	0.630898509578975
GO:0008171	O-methyltransferase activity	2/562	23/18639	0.0869565217391304	2.88395481974315	0.151795130124265	0.630898509578975
GO:0019001	guanyl nucleotide binding	16/562	400/18639	0.04	1.32661921708185	0.15431650423172	0.632986742865274
GO:0032561	guanyl ribonucleotide binding	16/562	400/18639	0.04	1.32661921708185	0.15431650423172	0.632986742865274
GO:0008080	N-acetyltransferase activity	4/562	69/18639	0.0579710144927536	1.92263654649544	0.154677211602417	0.632986742865274
GO:0000287	magnesium ion binding	10/562	230/18639	0.0434782608695652	1.44197740987158	0.158500785161029	0.645324625298475
GO:0004180	carboxypeptidase activity	3/562	46/18639	0.0652173913043478	2.16296611480736	0.160876370478656	0.648214460515319
GO:0030291	protein serine/threonine kinase inhibitor activity	3/562	46/18639	0.0652173913043478	2.16296611480736	0.160876370478656	0.648214460515319
GO:0060229	lipase activator activity	2/562	24/18639	0.0833333333333333	2.76379003558719	0.16245976454018	0.648214460515319
GO:0070840	dynein complex binding	2/562	24/18639	0.0833333333333333	2.76379003558719	0.16245976454018	0.648214460515319
GO:0004896	cytokine receptor activity	5/562	96/18639	0.0520833333333333	1.72736877224199	0.164097192913922	0.649945501172175
GO:0003714	transcription corepressor activity	9/562	204/18639	0.0441176470588235	1.46318296001675	0.164522545409498	0.649945501172175
GO:0005504	fatty acid binding	3/562	47/18639	0.0638297872340425	2.11694555917317	0.168255203879492	0.661417008353866
GO:0001848	complement binding	2/562	25/18639	0.08	2.6532384341637	0.173253302675869	0.667904036402625
GO:0017025	TBP-class protein binding	2/562	25/18639	0.08	2.6532384341637	0.173253302675869	0.667904036402625
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/562	25/18639	0.08	2.6532384341637	0.173253302675869	0.667904036402625
GO:0019707	protein-cysteine S-acyltransferase activity	2/562	25/18639	0.08	2.6532384341637	0.173253302675869	0.667904036402625
GO:0004521	RNA endonuclease activity	4/562	73/18639	0.0547945205479452	1.81728659874226	0.178096428899596	0.68327379933595
GO:0051015	actin filament binding	9/562	209/18639	0.0430622009569378	1.42817858298285	0.181354848819911	0.692445786403296
GO:0005160	transforming growth factor beta receptor binding	2/562	26/18639	0.0769230769230769	2.55119080208048	0.184158319145424	0.696485017431509
GO:0050750	low-density lipoprotein particle receptor binding	2/562	26/18639	0.0769230769230769	2.55119080208048	0.184158319145424	0.696485017431509
GO:0008237	metallopeptidase activity	8/562	184/18639	0.0434782608695652	1.44197740987158	0.192737123211423	0.725491624163752
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/562	27/18639	0.0740740740740741	2.45670225385528	0.195158318759558	0.727739898925828
GO:0035255	ionotropic glutamate receptor binding	2/562	27/18639	0.0740740740740741	2.45670225385528	0.195158318759558	0.727739898925828
GO:0051536	iron-sulfur cluster binding	4/562	76/18639	0.0526315789473684	1.74555160142349	0.196391406127742	0.728931823674131
GO:0051540	metal cluster binding	4/562	77/18639	0.051948051948052	1.7228821001063	0.202614212938413	0.748546953355803
GO:0008234	cysteine-type peptidase activity	8/562	187/18639	0.0427807486631016	1.41884408244048	0.204312642202833	0.751343264874935
GO:0051019	mitogen-activated protein kinase binding	2/562	28/18639	0.0714285714285714	2.36896288764616	0.206237696439647	0.754943494306598
GO:0099106	ion channel regulator activity	7/562	160/18639	0.04375	1.45098976868327	0.209303136811679	0.76083594543796
GO:0045296	cadherin binding	13/562	334/18639	0.0389221556886228	1.29087199266947	0.210608628708677	0.76083594543796
GO:0033218	amide binding	10/562	247/18639	0.0404858299595142	1.34273200109499	0.21369124950494	0.76083594543796
GO:0005246	calcium channel regulator activity	3/562	53/18639	0.0566037735849057	1.87729134492715	0.214349497401661	0.76083594543796
GO:0016251	RNA polymerase II general transcription initiation factor activity	3/562	53/18639	0.0566037735849057	1.87729134492715	0.214349497401661	0.76083594543796
GO:0034212	protein N-acetyltransferase activity	3/562	53/18639	0.0566037735849057	1.87729134492715	0.214349497401661	0.76083594543796
GO:0046332	SMAD binding	4/562	79/18639	0.0506329113924051	1.67926483174918	0.215229934234655	0.76083594543796
GO:0003785	actin monomer binding	2/562	29/18639	0.0689655172413793	2.28727451221009	0.21738169869656	0.76083594543796
GO:0004181	metallocarboxypeptidase activity	2/562	29/18639	0.0689655172413793	2.28727451221009	0.21738169869656	0.76083594543796
GO:0016417	S-acyltransferase activity	2/562	29/18639	0.0689655172413793	2.28727451221009	0.21738169869656	0.76083594543796
GO:0003925	G protein activity	3/562	54/18639	0.0555555555555556	1.84252669039146	0.222283173515512	0.771225967240776
GO:0050661	NADP binding	3/562	54/18639	0.0555555555555556	1.84252669039146	0.222283173515512	0.771225967240776
GO:0044325	transmembrane transporter binding	6/562	136/18639	0.0441176470588235	1.46318296001675	0.228007332866014	0.78284959879853
GO:0015101	organic cation transmembrane transporter activity	4/562	81/18639	0.0493827160493827	1.63780150257019	0.228054024442363	0.78284959879853
GO:0016769	transferase activity, transferring nitrogenous groups	2/562	30/18639	0.0666666666666667	2.21103202846975	0.228576386616613	0.78284959879853
GO:0016922	nuclear receptor binding	6/562	137/18639	0.0437956204379562	1.45250279242538	0.23291866065024	0.79431235555082
GO:0070273	phosphatidylinositol-4-phosphate binding	2/562	31/18639	0.0645161290322581	2.13970841464815	0.239808600299038	0.803435586623781
GO:0072349	modified amino acid transmembrane transporter activity	2/562	31/18639	0.0645161290322581	2.13970841464815	0.239808600299038	0.803435586623781
GO:0016247	channel regulator activity	7/562	168/18639	0.0416666666666667	1.38189501779359	0.244654850404898	0.803435586623781
GO:0005200	structural constituent of cytoskeleton	5/562	112/18639	0.0446428571428571	1.48060180477885	0.24939006954685	0.803435586623781
GO:0030515	snoRNA binding	2/562	32/18639	0.0625	2.07284252669039	0.251065924691329	0.803435586623781
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/562	32/18639	0.0625	2.07284252669039	0.251065924691329	0.803435586623781
GO:0141108	transporter regulator activity	7/562	170/18639	0.0411764705882353	1.36563742934896	0.253775263800947	0.803435586623781
GO:0001786	phosphatidylserine binding	3/562	59/18639	0.0508474576271186	1.68638036069727	0.262708590123243	0.803435586623781
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0005381	iron ion transmembrane transporter activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0005522	profilin binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0005528	FK506 binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0008401	retinoic acid 4-hydroxylase activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0015187	glycine transmembrane transporter activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0015203	polyamine transmembrane transporter activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0031434	mitogen-activated protein kinase kinase binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0032395	MHC class II receptor activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0035256	G protein-coupled glutamate receptor binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0047429	nucleoside triphosphate diphosphatase activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0050815	phosphoserine residue binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0051378	serotonin binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0051880	G-quadruplex DNA binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:1905394	retromer complex binding	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:1990757	ubiquitin ligase activator activity	1/562	10/18639	0.1	3.31654804270463	0.263784616159688	0.803435586623781
GO:0016229	steroid dehydrogenase activity	2/562	35/18639	0.0571428571428571	1.89517031011693	0.284874904163232	0.807282140061862
GO:0034061	DNA polymerase activity	2/562	35/18639	0.0571428571428571	1.89517031011693	0.284874904163232	0.807282140061862
GO:0043015	gamma-tubulin binding	2/562	35/18639	0.0571428571428571	1.89517031011693	0.284874904163232	0.807282140061862
GO:0061631	ubiquitin conjugating enzyme activity	2/562	35/18639	0.0571428571428571	1.89517031011693	0.284874904163232	0.807282140061862
GO:0001851	complement component C3b binding	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0003953	NAD+ nucleosidase activity	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0005114	type II transforming growth factor beta receptor binding	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0008503	benzodiazepine receptor activity	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0032050	clathrin heavy chain binding	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0032794	GTPase activating protein binding	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0034713	type I transforming growth factor beta receptor binding	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0048185	activin binding	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0180030	inositol phosphate kinase activity	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:1990948	ubiquitin ligase inhibitor activity	1/562	11/18639	0.0909090909090909	3.01504367518602	0.285994774821894	0.807282140061862
GO:0015179	L-amino acid transmembrane transporter activity	3/562	62/18639	0.0483870967741935	1.60478131098611	0.287390653994622	0.807282140061862
GO:0072341	modified amino acid binding	4/562	91/18639	0.043956043956044	1.45782331547456	0.294538223234427	0.807282140061862
GO:1901682	sulfur compound transmembrane transporter activity	3/562	63/18639	0.0476190476190476	1.57930859176411	0.295660965997335	0.807282140061862
GO:0004190	aspartic-type endopeptidase activity	2/562	36/18639	0.0555555555555556	1.84252669039146	0.296122296073571	0.807282140061862
GO:0016409	palmitoyltransferase activity	2/562	36/18639	0.0555555555555556	1.84252669039146	0.296122296073571	0.807282140061862
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/562	36/18639	0.0555555555555556	1.84252669039146	0.296122296073571	0.807282140061862
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/562	36/18639	0.0555555555555556	1.84252669039146	0.296122296073571	0.807282140061862
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/562	36/18639	0.0555555555555556	1.84252669039146	0.296122296073571	0.807282140061862
GO:0004540	RNA nuclease activity	5/562	121/18639	0.0413223140495868	1.37047439781183	0.301532985348109	0.807282140061862
GO:0070001	aspartic-type peptidase activity	2/562	37/18639	0.0540540540540541	1.79272867173223	0.307342791877745	0.807282140061862
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/562	122/18639	0.040983606557377	1.35924100110845	0.30743927524532	0.807282140061862
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0004126	cytidine deaminase activity	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0005025	transforming growth factor beta receptor activity, type I	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0005026	transforming growth factor beta receptor activity, type II	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0005527	macrolide binding	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0008603	cAMP-dependent protein kinase regulator activity	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0015269	calcium-activated potassium channel activity	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0016361	activin receptor activity, type I	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0016362	activin receptor activity, type II	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0017002	activin receptor activity	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0070008	serine-type exopeptidase activity	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0097371	MDM2/MDM4 family protein binding	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:1990459	transferrin receptor binding	1/562	12/18639	0.0833333333333333	2.76379003558719	0.3075360533569	0.807282140061862
GO:0120013	lipid transfer activity	3/562	65/18639	0.0461538461538462	1.53071448124829	0.312239719521215	0.81416918976357
GO:0016410	N-acyltransferase activity	4/562	94/18639	0.0425531914893617	1.41129703944878	0.314995206202406	0.81416918976357
GO:0008017	microtubule binding	10/562	276/18639	0.036231884057971	1.20164784155965	0.321989862740489	0.81416918976357
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0004993	G protein-coupled serotonin receptor activity	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0005542	folic acid binding	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0008035	high-density lipoprotein particle binding	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0019104	DNA N-glycosylase activity	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0035325	Toll-like receptor binding	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0035673	oligopeptide transmembrane transporter activity	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0039706	co-receptor binding	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0045159	myosin II binding	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0070123	transforming growth factor beta receptor activity, type III	1/562	13/18639	0.0769230769230769	2.55119080208048	0.328428560900435	0.81416918976357
GO:0016407	acetyltransferase activity	4/562	96/18639	0.0416666666666667	1.38189501779359	0.328701726043341	0.81416918976357
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	3/562	67/18639	0.0447761194029851	1.48502151165879	0.328841641970883	0.81416918976357
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/562	39/18639	0.0512820512820513	1.70079386805365	0.32966927015764	0.81416918976357
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/562	39/18639	0.0512820512820513	1.70079386805365	0.32966927015764	0.81416918976357
GO:0140375	immune receptor activity	6/562	156/18639	0.0384615384615385	1.27559540104024	0.331149652629448	0.81416918976357
GO:0005543	phospholipid binding	17/562	497/18639	0.03420523138833	1.13443293211225	0.331585196332281	0.81416918976357
GO:0005261	monoatomic cation channel activity	12/562	341/18639	0.0351906158357771	1.16711368071717	0.333558015645302	0.81650090946304
GO:0030246	carbohydrate binding	10/562	280/18639	0.0357142857142857	1.18448144382308	0.337862134242016	0.817856275556909
GO:0071855	neuropeptide receptor binding	2/562	40/18639	0.05	1.65827402135231	0.340759667218189	0.817856275556909
GO:0140662	ATP-dependent protein folding chaperone	2/562	40/18639	0.05	1.65827402135231	0.340759667218189	0.817856275556909
GO:0004705	JUN kinase activity	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:0008195	phosphatidate phosphatase activity	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:0019992	diacylglycerol binding	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:0031404	chloride ion binding	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:0071933	Arp2/3 complex binding	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:0098821	BMP receptor activity	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:1901612	cardiolipin binding	1/562	14/18639	0.0714285714285714	2.36896288764616	0.348691803076638	0.817856275556909
GO:0016859	cis-trans isomerase activity	2/562	42/18639	0.0476190476190476	1.57930859176411	0.362759542508739	0.817856275556909
GO:0031492	nucleosomal DNA binding	2/562	42/18639	0.0476190476190476	1.57930859176411	0.362759542508739	0.817856275556909
GO:0042056	chemoattractant activity	2/562	42/18639	0.0476190476190476	1.57930859176411	0.362759542508739	0.817856275556909
GO:0005179	hormone activity	5/562	132/18639	0.0378787878787879	1.25626819799418	0.367152316080265	0.817856275556909
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	5/562	132/18639	0.0378787878787879	1.25626819799418	0.367152316080265	0.817856275556909
GO:0000774	adenyl-nucleotide exchange factor activity	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0008242	omega peptidase activity	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0017081	chloride channel regulator activity	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0031005	filamin binding	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0033130	acetylcholine receptor binding	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0050780	dopamine receptor binding	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0051371	muscle alpha-actinin binding	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0061578	K63-linked deubiquitinase activity	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0120283	protein serine/threonine kinase binding	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0140161	monocarboxylate:sodium symporter activity	1/562	15/18639	0.0666666666666667	2.21103202846975	0.368344700079104	0.817856275556909
GO:0008236	serine-type peptidase activity	7/562	194/18639	0.0360824742268041	1.19669259272847	0.368990890193179	0.817856275556909
GO:0015171	amino acid transmembrane transporter activity	4/562	102/18639	0.0392156862745098	1.30060707557044	0.369946408304639	0.817856275556909
GO:0008200	ion channel inhibitor activity	2/562	43/18639	0.0465116279069767	1.5425804849789	0.373656322840909	0.817856275556909
GO:0005216	monoatomic ion channel activity	15/562	448/18639	0.0334821428571429	1.11045135358414	0.376079452427489	0.817856275556909
GO:0016248	channel inhibitor activity	2/562	44/18639	0.0454545454545455	1.50752183759301	0.384476591655828	0.817856275556909
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/562	44/18639	0.0454545454545455	1.50752183759301	0.384476591655828	0.817856275556909
GO:0031491	nucleosome binding	3/562	74/18639	0.0405405405405405	1.34454650379917	0.386692374985777	0.817856275556909
GO:0004707	MAP kinase activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0005024	transforming growth factor beta receptor activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0005149	interleukin-1 receptor binding	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0005521	lamin binding	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0008142	oxysterol binding	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0008296	3'-5'-DNA exonuclease activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0015378	sodium:chloride symporter activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0015562	efflux transmembrane transporter activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0016722	oxidoreductase activity, acting on metal ions	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0017070	U6 snRNA binding	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0022858	alanine transmembrane transporter activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0030275	LRR domain binding	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0070411	I-SMAD binding	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0097027	ubiquitin-protein transferase activator activity	1/562	16/18639	0.0625	2.07284252669039	0.387405604211167	0.817856275556909
GO:0017171	serine hydrolase activity	7/562	198/18639	0.0353535353535354	1.17251698479456	0.388748017406639	0.818524849315297
GO:0016779	nucleotidyltransferase activity	5/562	136/18639	0.0367647058823529	1.21931913334729	0.39115688042712	0.819273466091449
GO:0019838	growth factor binding	5/562	136/18639	0.0367647058823529	1.21931913334729	0.39115688042712	0.819273466091449
GO:0046915	transition metal ion transmembrane transporter activity	2/562	45/18639	0.0444444444444444	1.47402135231317	0.39521505737916	0.823450693964935
GO:0141110	transporter inhibitor activity	2/562	45/18639	0.0444444444444444	1.47402135231317	0.39521505737916	0.823450693964935
GO:0000149	SNARE binding	4/562	106/18639	0.0377358490566038	1.25152756328476	0.397374429185656	0.825793735651442
GO:0140297	DNA-binding transcription factor binding	16/562	488/18639	0.0327868852459016	1.08739280088676	0.401748138451262	0.826280787978191
GO:0004549	tRNA-specific ribonuclease activity	1/562	17/18639	0.0588235294117647	1.95091061335566	0.405892316901567	0.826280787978191
GO:0005092	GDP-dissociation inhibitor activity	1/562	17/18639	0.0588235294117647	1.95091061335566	0.405892316901567	0.826280787978191
GO:0015278	intracellularly gated calcium channel activity	1/562	17/18639	0.0588235294117647	1.95091061335566	0.405892316901567	0.826280787978191
GO:0017110	nucleoside diphosphate phosphatase activity	1/562	17/18639	0.0588235294117647	1.95091061335566	0.405892316901567	0.826280787978191
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/562	17/18639	0.0588235294117647	1.95091061335566	0.405892316901567	0.826280787978191
GO:0030548	acetylcholine receptor regulator activity	1/562	17/18639	0.0588235294117647	1.95091061335566	0.405892316901567	0.826280787978191
GO:0070402	NADPH binding	1/562	17/18639	0.0588235294117647	1.95091061335566	0.405892316901567	0.826280787978191
GO:0070851	growth factor receptor binding	5/562	139/18639	0.0359712230215827	1.19300289305922	0.40912037380738	0.828439884331823
GO:0061733	protein-lysine-acetyltransferase activity	2/562	47/18639	0.0425531914893617	1.41129703944878	0.416427331963311	0.828439884331823
GO:0000900	mRNA regulatory element binding translation repressor activity	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0004706	JUN kinase kinase kinase activity	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0015373	monoatomic anion:sodium symporter activity	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0016854	racemase and epimerase activity	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0017075	syntaxin-1 binding	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0035615	clathrin adaptor activity	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0070628	proteasome binding	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0099602	neurotransmitter receptor regulator activity	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:1901611	phosphatidylglycerol binding	1/562	18/18639	0.0555555555555556	1.84252669039146	0.423822105211165	0.828439884331823
GO:0004222	metalloendopeptidase activity	4/562	110/18639	0.0363636363636364	1.20601747007441	0.42459982886685	0.828439884331823
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/562	48/18639	0.0416666666666667	1.38189501779359	0.426892421701786	0.828439884331823
GO:0032266	phosphatidylinositol-3-phosphate binding	2/562	48/18639	0.0416666666666667	1.38189501779359	0.426892421701786	0.828439884331823
GO:0015370	solute:sodium symporter activity	3/562	79/18639	0.0379746835443038	1.25944862381188	0.427304632742331	0.828439884331823
GO:0033293	monocarboxylic acid binding	3/562	79/18639	0.0379746835443038	1.25944862381188	0.427304632742331	0.828439884331823
GO:0001222	transcription corepressor binding	2/562	49/18639	0.0408163265306122	1.35369307865495	0.437258235390602	0.828439884331823
GO:0060590	ATPase regulator activity	2/562	49/18639	0.0408163265306122	1.35369307865495	0.437258235390602	0.828439884331823
GO:0004252	serine-type endopeptidase activity	6/562	176/18639	0.0340909090909091	1.13064137819476	0.438736656444781	0.828439884331823
GO:0019903	protein phosphatase binding	5/562	144/18639	0.0347222222222222	1.15157918149466	0.438879321900807	0.828439884331823
GO:0003756	protein disulfide isomerase activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0015245	fatty acid transmembrane transporter activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0042577	lipid phosphatase activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0043395	heparan sulfate proteoglycan binding	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0050145	nucleoside monophosphate kinase activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0099589	serotonin receptor activity	1/562	19/18639	0.0526315789473684	1.74555160142349	0.441211717845896	0.828439884331823
GO:0001618	virus receptor activity	3/562	81/18639	0.037037037037037	1.22835112692764	0.443290132097729	0.83038855730983
GO:0005539	glycosaminoglycan binding	8/562	242/18639	0.0330578512396694	1.09637951824946	0.446338779899606	0.834141326369755
GO:0140272	exogenous protein binding	3/562	82/18639	0.0365853658536585	1.21337123513584	0.451217454106366	0.841288617702991
GO:0016830	carbon-carbon lyase activity	2/562	51/18639	0.0392156862745098	1.30060707557044	0.457678209981039	0.844148287223778
GO:0001972	retinoic acid binding	1/562	20/18639	0.05	1.65827402135231	0.458077400690719	0.844148287223778
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/562	20/18639	0.05	1.65827402135231	0.458077400690719	0.844148287223778
GO:0042288	MHC class I protein binding	1/562	20/18639	0.05	1.65827402135231	0.458077400690719	0.844148287223778
GO:0052745	inositol phosphate phosphatase activity	1/562	20/18639	0.05	1.65827402135231	0.458077400690719	0.844148287223778
GO:0030165	PDZ domain binding	3/562	83/18639	0.036144578313253	1.19875230459203	0.459098191297143	0.844148287223778
GO:0008509	monoatomic anion transmembrane transporter activity	5/562	149/18639	0.0335570469798658	1.11293558480021	0.468283057276869	0.859057194728601
GO:0001846	opsonin binding	1/562	21/18639	0.0476190476190476	1.57930859176411	0.47443491187885	0.85931957206287
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/562	21/18639	0.0476190476190476	1.57930859176411	0.47443491187885	0.85931957206287
GO:0051428	peptide hormone receptor binding	1/562	21/18639	0.0476190476190476	1.57930859176411	0.47443491187885	0.85931957206287
GO:0140312	cargo adaptor activity	1/562	21/18639	0.0476190476190476	1.57930859176411	0.47443491187885	0.85931957206287
GO:0005544	calcium-dependent phospholipid binding	2/562	53/18639	0.0377358490566038	1.25152756328476	0.477662540708855	0.85931957206287
GO:0016860	intramolecular oxidoreductase activity	2/562	53/18639	0.0377358490566038	1.25152756328476	0.477662540708855	0.85931957206287
GO:0017046	peptide hormone binding	2/562	53/18639	0.0377358490566038	1.25152756328476	0.477662540708855	0.85931957206287
GO:0140296	general transcription initiation factor binding	2/562	53/18639	0.0377358490566038	1.25152756328476	0.477662540708855	0.85931957206287
GO:0140104	molecular carrier activity	8/562	249/18639	0.0321285140562249	1.06555760408181	0.478117656636484	0.85931957206287
GO:0050660	flavin adenine dinucleotide binding	3/562	86/18639	0.0348837209302326	1.15693536373417	0.482440402059023	0.86514031650135
GO:0005243	gap junction channel activity	1/562	22/18639	0.0454545454545455	1.50752183759301	0.490299536410168	0.869464511234032
GO:0015377	chloride:monoatomic cation symporter activity	1/562	22/18639	0.0454545454545455	1.50752183759301	0.490299536410168	0.869464511234032
GO:0033691	sialic acid binding	1/562	22/18639	0.0454545454545455	1.50752183759301	0.490299536410168	0.869464511234032
GO:0050321	tau-protein kinase activity	1/562	22/18639	0.0454545454545455	1.50752183759301	0.490299536410168	0.869464511234032
GO:0061133	endopeptidase activator activity	1/562	22/18639	0.0454545454545455	1.50752183759301	0.490299536410168	0.869464511234032
GO:0015631	tubulin binding	12/562	385/18639	0.0311688311688312	1.03372926006378	0.494787919512275	0.874533061549155
GO:0031406	carboxylic acid binding	6/562	187/18639	0.0320855614973262	1.06413306183036	0.496818693992114	0.874533061549155
GO:0140313	molecular sequestering activity	2/562	55/18639	0.0363636363636364	1.20601747007441	0.497190885962859	0.874533061549155
GO:0015108	chloride transmembrane transporter activity	4/562	121/18639	0.0330578512396694	1.09637951824946	0.497541365843755	0.874533061549155
GO:0046943	carboxylic acid transmembrane transporter activity	6/562	188/18639	0.0319148936170213	1.05847277958658	0.502005027657752	0.876025244669477
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/562	23/18639	0.0434782608695652	1.44197740987158	0.505686100332255	0.876025244669477
GO:0031681	G-protein beta-subunit binding	1/562	23/18639	0.0434782608695652	1.44197740987158	0.505686100332255	0.876025244669477
GO:0099186	structural constituent of postsynapse	1/562	23/18639	0.0434782608695652	1.44197740987158	0.505686100332255	0.876025244669477
GO:0019212	phosphatase inhibitor activity	2/562	56/18639	0.0357142857142857	1.18448144382308	0.506778796394691	0.876025244669477
GO:0170055	lipid transmembrane transporter activity	2/562	56/18639	0.0357142857142857	1.18448144382308	0.506778796394691	0.876025244669477
GO:0005342	organic acid transmembrane transporter activity	6/562	189/18639	0.0317460317460317	1.05287239450941	0.507172510071802	0.876025244669477
GO:0043177	organic acid binding	6/562	189/18639	0.0317460317460317	1.05287239450941	0.507172510071802	0.876025244669477
GO:0019902	phosphatase binding	6/562	190/18639	0.0315789473684211	1.04733096085409	0.512320456881605	0.883005884646913
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/562	24/18639	0.0416666666666667	1.38189501779359	0.520608984497128	0.883927594954698
GO:0005540	hyaluronic acid binding	1/562	24/18639	0.0416666666666667	1.38189501779359	0.520608984497128	0.883927594954698
GO:0035035	histone acetyltransferase binding	1/562	24/18639	0.0416666666666667	1.38189501779359	0.520608984497128	0.883927594954698
GO:0048027	mRNA 5'-UTR binding	1/562	24/18639	0.0416666666666667	1.38189501779359	0.520608984497128	0.883927594954698
GO:0050431	transforming growth factor beta binding	1/562	24/18639	0.0416666666666667	1.38189501779359	0.520608984497128	0.883927594954698
GO:0050699	WW domain binding	1/562	24/18639	0.0416666666666667	1.38189501779359	0.520608984497128	0.883927594954698
GO:0070300	phosphatidic acid binding	1/562	24/18639	0.0416666666666667	1.38189501779359	0.520608984497128	0.883927594954698
GO:0008408	3'-5' exonuclease activity	2/562	58/18639	0.0344827586206897	1.14363725610504	0.525593538552429	0.884962583534546
GO:0015459	potassium channel regulator activity	2/562	59/18639	0.0338983050847458	1.12425357379818	0.534817571830646	0.884962583534546
GO:0045309	protein phosphorylated amino acid binding	2/562	59/18639	0.0338983050847458	1.12425357379818	0.534817571830646	0.884962583534546
GO:0070063	RNA polymerase binding	2/562	59/18639	0.0338983050847458	1.12425357379818	0.534817571830646	0.884962583534546
GO:0003707	nuclear steroid receptor activity	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0004709	MAP kinase kinase kinase activity	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0008483	transaminase activity	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0015271	outward rectifier potassium channel activity	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0015662	P-type ion transporter activity	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0140358	P-type transmembrane transporter activity	1/562	25/18639	0.04	1.32661921708185	0.535082137906347	0.884962583534546
GO:0004519	endonuclease activity	4/562	127/18639	0.031496062992126	1.04458206069437	0.535635247928804	0.884962583534546
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	4/562	128/18639	0.03125	1.0364212633452	0.541843849471083	0.887038531060959
GO:0042562	hormone binding	3/562	94/18639	0.0319148936170213	1.05847277958658	0.542179671312571	0.887038531060959
GO:0001098	basal transcription machinery binding	2/562	60/18639	0.0333333333333333	1.10551601423488	0.543917835091786	0.887038531060959
GO:0001099	basal RNA polymerase II transcription machinery binding	2/562	60/18639	0.0333333333333333	1.10551601423488	0.543917835091786	0.887038531060959
GO:0004529	DNA exonuclease activity	1/562	26/18639	0.0384615384615385	1.27559540104024	0.549119090656784	0.887038531060959
GO:0005227	calcium-activated cation channel activity	1/562	26/18639	0.0384615384615385	1.27559540104024	0.549119090656784	0.887038531060959
GO:0008157	protein phosphatase 1 binding	1/562	26/18639	0.0384615384615385	1.27559540104024	0.549119090656784	0.887038531060959
GO:0019865	immunoglobulin binding	1/562	26/18639	0.0384615384615385	1.27559540104024	0.549119090656784	0.887038531060959
GO:0050681	nuclear androgen receptor binding	1/562	26/18639	0.0384615384615385	1.27559540104024	0.549119090656784	0.887038531060959
GO:0070006	metalloaminopeptidase activity	1/562	26/18639	0.0384615384615385	1.27559540104024	0.549119090656784	0.887038531060959
GO:0070412	R-SMAD binding	1/562	26/18639	0.0384615384615385	1.27559540104024	0.549119090656784	0.887038531060959
GO:0016836	hydro-lyase activity	2/562	61/18639	0.0327868852459016	1.08739280088676	0.552893394906583	0.889534131321479
GO:0019905	syntaxin binding	2/562	61/18639	0.0327868852459016	1.08739280088676	0.552893394906583	0.889534131321479
GO:0004364	glutathione transferase activity	1/562	27/18639	0.037037037037037	1.22835112692764	0.562732966498985	0.899921657848076
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/562	27/18639	0.037037037037037	1.22835112692764	0.562732966498985	0.899921657848076
GO:0008395	steroid hydroxylase activity	1/562	27/18639	0.037037037037037	1.22835112692764	0.562732966498985	0.899921657848076
GO:0046966	nuclear thyroid hormone receptor binding	1/562	28/18639	0.0357142857142857	1.18448144382308	0.575936495019701	0.91371237182052
GO:0051393	alpha-actinin binding	1/562	28/18639	0.0357142857142857	1.18448144382308	0.575936495019701	0.91371237182052
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/562	28/18639	0.0357142857142857	1.18448144382308	0.575936495019701	0.91371237182052
GO:0097718	disordered domain specific binding	1/562	28/18639	0.0357142857142857	1.18448144382308	0.575936495019701	0.91371237182052
GO:0051087	protein-folding chaperone binding	4/562	134/18639	0.0298507462686567	0.990014341105859	0.57817144939205	0.91503735133544
GO:0004536	DNA nuclease activity	2/562	64/18639	0.03125	1.0364212633452	0.579064990506764	0.91503735133544
GO:0035250	UDP-galactosyltransferase activity	1/562	29/18639	0.0344827586206897	1.14363725610504	0.588742023459813	0.924834910867975
GO:0051861	glycolipid binding	1/562	29/18639	0.0344827586206897	1.14363725610504	0.588742023459813	0.924834910867975
GO:0099604	ligand-gated calcium channel activity	1/562	29/18639	0.0344827586206897	1.14363725610504	0.588742023459813	0.924834910867975
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/562	30/18639	0.0333333333333333	1.10551601423488	0.601161528178545	0.931508542692192
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/562	30/18639	0.0333333333333333	1.10551601423488	0.601161528178545	0.931508542692192
GO:0022839	monoatomic ion-gated channel activity	1/562	30/18639	0.0333333333333333	1.10551601423488	0.601161528178545	0.931508542692192
GO:0031210	phosphatidylcholine binding	1/562	30/18639	0.0333333333333333	1.10551601423488	0.601161528178545	0.931508542692192
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/562	30/18639	0.0333333333333333	1.10551601423488	0.601161528178545	0.931508542692192
GO:0048019	receptor antagonist activity	1/562	30/18639	0.0333333333333333	1.10551601423488	0.601161528178545	0.931508542692192
GO:0098918	structural constituent of synapse	1/562	30/18639	0.0333333333333333	1.10551601423488	0.601161528178545	0.931508542692192
GO:0005253	monoatomic anion channel activity	3/562	103/18639	0.029126213592233	0.965984866807173	0.604368630040305	0.933214732354299
GO:0004518	nuclease activity	6/562	209/18639	0.0287081339712919	0.952119055321902	0.605627485951943	0.933214732354299
GO:0003823	antigen binding	5/562	174/18639	0.028735632183908	0.953031046754203	0.605770966615949	0.933214732354299
GO:0030145	manganese ion binding	2/562	68/18639	0.0294117647058824	0.975455306677831	0.612185324132975	0.935635439898557
GO:0005164	tumor necrosis factor receptor binding	1/562	31/18639	0.032258064516129	1.06985420732407	0.613206625774528	0.935635439898557
GO:0005184	neuropeptide hormone activity	1/562	31/18639	0.032258064516129	1.06985420732407	0.613206625774528	0.935635439898557
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/562	31/18639	0.032258064516129	1.06985420732407	0.613206625774528	0.935635439898557
GO:0047499	calcium-independent phospholipase A2 activity	1/562	31/18639	0.032258064516129	1.06985420732407	0.613206625774528	0.935635439898557
GO:0140098	catalytic activity, acting on RNA	11/562	387/18639	0.0284237726098191	0.94268807415377	0.621868846131669	0.935635439898557
GO:0004497	monooxygenase activity	3/562	106/18639	0.0283018867924528	0.938645672463574	0.623814595178229	0.935635439898557
GO:0008013	beta-catenin binding	3/562	106/18639	0.0283018867924528	0.938645672463574	0.623814595178229	0.935635439898557
GO:0008378	galactosyltransferase activity	1/562	32/18639	0.03125	1.0364212633452	0.624888583873986	0.935635439898557
GO:0051059	NF-kappaB binding	1/562	32/18639	0.03125	1.0364212633452	0.624888583873986	0.935635439898557
GO:0071813	lipoprotein particle binding	1/562	32/18639	0.03125	1.0364212633452	0.624888583873986	0.935635439898557
GO:0071814	protein-lipid complex binding	1/562	32/18639	0.03125	1.0364212633452	0.624888583873986	0.935635439898557
GO:0160041	neuropeptide activity	1/562	32/18639	0.03125	1.0364212633452	0.624888583873986	0.935635439898557
GO:0005319	lipid transporter activity	5/562	178/18639	0.0280898876404494	0.931614618737255	0.62582276186929	0.935635439898557
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/562	70/18639	0.0285714285714286	0.947585155058465	0.627984148634224	0.935635439898557
GO:0016782	transferase activity, transferring sulphur-containing groups	2/562	70/18639	0.0285714285714286	0.947585155058465	0.627984148634224	0.935635439898557
GO:0097110	scaffold protein binding	2/562	70/18639	0.0285714285714286	0.947585155058465	0.627984148634224	0.935635439898557
GO:0016853	isomerase activity	5/562	180/18639	0.0277777777777778	0.921263345195729	0.635615928285058	0.935635439898557
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/562	33/18639	0.0303030303030303	1.00501455839534	0.636218331595962	0.935635439898557
GO:0019239	deaminase activity	1/562	33/18639	0.0303030303030303	1.00501455839534	0.636218331595962	0.935635439898557
GO:0019956	chemokine binding	1/562	33/18639	0.0303030303030303	1.00501455839534	0.636218331595962	0.935635439898557
GO:0030296	protein tyrosine kinase activator activity	1/562	33/18639	0.0303030303030303	1.00501455839534	0.636218331595962	0.935635439898557
GO:0140311	protein sequestering activity	1/562	33/18639	0.0303030303030303	1.00501455839534	0.636218331595962	0.935635439898557
GO:0140416	transcription regulator inhibitor activity	1/562	33/18639	0.0303030303030303	1.00501455839534	0.636218331595962	0.935635439898557
GO:0008175	tRNA methyltransferase activity	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0008376	acetylgalactosaminyltransferase activity	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0016831	carboxy-lyase activity	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0019825	oxygen binding	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0030332	cyclin binding	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0051427	hormone receptor binding	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:0090482	vitamin transmembrane transporter activity	1/562	34/18639	0.0294117647058824	0.975455306677831	0.647206469704265	0.935635439898557
GO:1902936	phosphatidylinositol bisphosphate binding	3/562	111/18639	0.027027027027027	0.896364335866115	0.65474641545957	0.943485477435981
GO:0000175	3'-5'-RNA exonuclease activity	1/562	35/18639	0.0285714285714286	0.947585155058465	0.657863280455472	0.943485477435981
GO:0004623	phospholipase A2 activity	1/562	35/18639	0.0285714285714286	0.947585155058465	0.657863280455472	0.943485477435981
GO:0005154	epidermal growth factor receptor binding	1/562	35/18639	0.0285714285714286	0.947585155058465	0.657863280455472	0.943485477435981
GO:1901981	phosphatidylinositol phosphate binding	5/562	185/18639	0.027027027027027	0.896364335866115	0.659399980420119	0.943485477435981
GO:0003725	double-stranded RNA binding	2/562	75/18639	0.0266666666666667	0.8844128113879	0.665282821470622	0.943485477435981
GO:0019842	vitamin binding	4/562	150/18639	0.0266666666666667	0.8844128113879	0.666460105402417	0.943485477435981
GO:0000993	RNA polymerase II complex binding	1/562	36/18639	0.0277777777777778	0.921263345195729	0.668198737152097	0.943485477435981
GO:0004033	aldo-keto reductase (NADPH) activity	1/562	36/18639	0.0277777777777778	0.921263345195729	0.668198737152097	0.943485477435981
GO:0005484	SNAP receptor activity	1/562	36/18639	0.0277777777777778	0.921263345195729	0.668198737152097	0.943485477435981
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/562	36/18639	0.0277777777777778	0.921263345195729	0.668198737152097	0.943485477435981
GO:0140597	protein carrier chaperone	5/562	188/18639	0.0265957446808511	0.882060649655486	0.673181361628387	0.943485477435981
GO:0001221	transcription coregulator binding	3/562	115/18639	0.0260869565217391	0.865186445922946	0.678148740436291	0.943485477435981
GO:0017124	SH3 domain binding	3/562	115/18639	0.0260869565217391	0.865186445922946	0.678148740436291	0.943485477435981
GO:0022829	wide pore channel activity	1/562	37/18639	0.027027027027027	0.896364335866115	0.678222513409718	0.943485477435981
GO:0030551	cyclic nucleotide binding	1/562	37/18639	0.027027027027027	0.896364335866115	0.678222513409718	0.943485477435981
GO:0042805	actinin binding	1/562	37/18639	0.027027027027027	0.896364335866115	0.678222513409718	0.943485477435981
GO:0003724	RNA helicase activity	2/562	77/18639	0.025974025974026	0.86144105005315	0.679336192741341	0.943485477435981
GO:0015294	solute:monoatomic cation symporter activity	3/562	116/18639	0.0258620689655172	0.857727942078783	0.683812518359326	0.943485477435981
GO:0019199	transmembrane receptor protein kinase activity	2/562	78/18639	0.0256410256410256	0.850396934026827	0.686180535624567	0.943485477435981
GO:0005506	iron ion binding	4/562	154/18639	0.025974025974026	0.86144105005315	0.68644351722893	0.943485477435981
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/562	38/18639	0.0263157894736842	0.872775800711744	0.687943992146614	0.943485477435981
GO:0042887	amide transmembrane transporter activity	1/562	38/18639	0.0263157894736842	0.872775800711744	0.687943992146614	0.943485477435981
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	6/562	229/18639	0.0262008733624454	0.868964552673701	0.692330872204643	0.943485477435981
GO:0008186	ATP-dependent activity, acting on RNA	2/562	79/18639	0.0253164556962025	0.839632415874589	0.692904585050079	0.943485477435981
GO:0016835	carbon-oxygen lyase activity	2/562	79/18639	0.0253164556962025	0.839632415874589	0.692904585050079	0.943485477435981
GO:0000217	DNA secondary structure binding	1/562	39/18639	0.0256410256410256	0.850396934026827	0.697372274304219	0.943485477435981
GO:0016757	glycosyltransferase activity	7/562	267/18639	0.0262172284644195	0.869506977488104	0.698327342711109	0.943485477435981
GO:0008514	organic anion transmembrane transporter activity	7/562	269/18639	0.0260223048327138	0.863042241595999	0.705631885996522	0.943485477435981
GO:0033192	calmodulin-dependent protein phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:0140791	histone H2AXS140 phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:1990439	MAP kinase serine/threonine phosphatase activity	2/562	81/18639	0.0246913580246914	0.818900751285093	0.705995921091102	0.943485477435981
GO:0004177	aminopeptidase activity	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:0004532	RNA exonuclease activity	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:0030331	nuclear estrogen receptor binding	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:0050997	quaternary ammonium group binding	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:0061791	GTPase motor activity	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:0071949	FAD binding	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:1990606	membrane scission GTPase motor activity	1/562	40/18639	0.025	0.829137010676157	0.706516187306425	0.943485477435981
GO:0003697	single-stranded DNA binding	3/562	121/18639	0.0247933884297521	0.822284638687098	0.711016428073634	0.943485477435981
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	2/562	82/18639	0.024390243902439	0.808914156757226	0.71236538276572	0.943485477435981
GO:0033549	MAP kinase phosphatase activity	2/562	82/18639	0.024390243902439	0.808914156757226	0.71236538276572	0.943485477435981
GO:0005096	GTPase activator activity	7/562	271/18639	0.025830258302583	0.856672926159867	0.712818755542644	0.943485477435981
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/562	41/18639	0.024390243902439	0.808914156757226	0.715384293265551	0.943485477435981
GO:0008227	G protein-coupled amine receptor activity	1/562	41/18639	0.024390243902439	0.808914156757226	0.715384293265551	0.943485477435981
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	2/562	83/18639	0.0240963855421687	0.799168203061356	0.718618893666179	0.943485477435981
GO:0005254	chloride channel activity	2/562	83/18639	0.0240963855421687	0.799168203061356	0.718618893666179	0.943485477435981
GO:0008135	translation factor activity, RNA binding	2/562	83/18639	0.0240963855421687	0.799168203061356	0.718618893666179	0.943485477435981
GO:0004402	histone acetyltransferase activity	1/562	42/18639	0.0238095238095238	0.789654295882054	0.723984896942546	0.943485477435981
GO:0008307	structural constituent of muscle	1/562	42/18639	0.0238095238095238	0.789654295882054	0.723984896942546	0.943485477435981
GO:0019894	kinesin binding	1/562	42/18639	0.0238095238095238	0.789654295882054	0.723984896942546	0.943485477435981
GO:0043175	RNA polymerase core enzyme binding	1/562	42/18639	0.0238095238095238	0.789654295882054	0.723984896942546	0.943485477435981
GO:0004527	exonuclease activity	2/562	84/18639	0.0238095238095238	0.789654295882054	0.724757641188291	0.943485477435981
GO:0017018	myosin phosphatase activity	2/562	84/18639	0.0238095238095238	0.789654295882054	0.724757641188291	0.943485477435981
GO:0180051	translation factor activity	2/562	84/18639	0.0238095238095238	0.789654295882054	0.724757641188291	0.943485477435981
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/562	43/18639	0.0232558139534884	0.771290242489448	0.732326053468776	0.947933239311312
GO:0008375	acetylglucosaminyltransferase activity	1/562	43/18639	0.0232558139534884	0.771290242489448	0.732326053468776	0.947933239311312
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/562	43/18639	0.0232558139534884	0.771290242489448	0.732326053468776	0.947933239311312
GO:0003712	transcription coregulator activity	13/562	495/18639	0.0262626262626263	0.871012617275962	0.73322344485755	0.947933239311312
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/562	86/18639	0.0232558139534884	0.771290242489448	0.736695761950928	0.947933239311312
GO:0015103	inorganic anion transmembrane transporter activity	4/562	165/18639	0.0242424242424242	0.804011646716273	0.736974014084401	0.947933239311312
GO:0001223	transcription coactivator binding	1/562	44/18639	0.0227272727272727	0.753760918796506	0.740415575836519	0.947933239311312
GO:0016790	thiolester hydrolase activity	1/562	44/18639	0.0227272727272727	0.753760918796506	0.740415575836519	0.947933239311312
GO:0043014	alpha-tubulin binding	1/562	44/18639	0.0227272727272727	0.753760918796506	0.740415575836519	0.947933239311312
GO:0019783	ubiquitin-like protein peptidase activity	3/562	127/18639	0.0236220472440945	0.783436545520778	0.741241029235913	0.947933239311312
GO:0042826	histone deacetylase binding	3/562	127/18639	0.0236220472440945	0.783436545520778	0.741241029235913	0.947933239311312
GO:0051539	4 iron, 4 sulfur cluster binding	1/562	45/18639	0.0222222222222222	0.737010676156584	0.748261042165095	0.953152862991222
GO:0005516	calmodulin binding	5/562	207/18639	0.0241545893719807	0.801098561039765	0.751713944126514	0.953152862991222
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/562	130/18639	0.0230769230769231	0.765357240624145	0.755385552353024	0.953152862991222
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/562	46/18639	0.0217391304347826	0.720988704935788	0.755869802749327	0.953152862991222
GO:0030276	clathrin binding	1/562	46/18639	0.0217391304347826	0.720988704935788	0.755869802749327	0.953152862991222
GO:0005262	calcium channel activity	3/562	131/18639	0.0229007633587786	0.759514818939991	0.759959969164589	0.953152862991222
GO:0031072	heat shock protein binding	3/562	131/18639	0.0229007633587786	0.759514818939991	0.759959969164589	0.953152862991222
GO:0001784	phosphotyrosine residue binding	1/562	47/18639	0.0212765957446809	0.705648519724389	0.763248986896849	0.953152862991222
GO:0043495	protein-membrane adaptor activity	1/562	47/18639	0.0212765957446809	0.705648519724389	0.763248986896849	0.953152862991222
GO:0061749	forked DNA-dependent helicase activity	1/562	47/18639	0.0212765957446809	0.705648519724389	0.763248986896849	0.953152862991222
GO:0140359	ABC-type transporter activity	1/562	47/18639	0.0212765957446809	0.705648519724389	0.763248986896849	0.953152862991222
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/562	47/18639	0.0212765957446809	0.705648519724389	0.763248986896849	0.953152862991222
GO:0008201	heparin binding	4/562	172/18639	0.0232558139534884	0.771290242489448	0.765786523231894	0.953152862991222
GO:0052689	carboxylic ester hydrolase activity	2/562	92/18639	0.0217391304347826	0.720988704935788	0.769888438251106	0.953152862991222
GO:0008188	neuropeptide receptor activity	1/562	48/18639	0.0208333333333333	0.690947508896797	0.770405509560574	0.953152862991222
GO:0009378	four-way junction helicase activity	1/562	48/18639	0.0208333333333333	0.690947508896797	0.770405509560574	0.953152862991222
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/562	48/18639	0.0208333333333333	0.690947508896797	0.770405509560574	0.953152862991222
GO:0036121	double-stranded DNA helicase activity	1/562	48/18639	0.0208333333333333	0.690947508896797	0.770405509560574	0.953152862991222
GO:0038187	pattern recognition receptor activity	1/562	48/18639	0.0208333333333333	0.690947508896797	0.770405509560574	0.953152862991222
GO:0043138	3'-5' DNA helicase activity	1/562	48/18639	0.0208333333333333	0.690947508896797	0.770405509560574	0.953152862991222
GO:0140693	molecular condensate scaffold activity	1/562	48/18639	0.0208333333333333	0.690947508896797	0.770405509560574	0.953152862991222
GO:0051219	phosphoprotein binding	2/562	93/18639	0.021505376344086	0.713236138216049	0.775052379679106	0.957417645485954
GO:0016763	pentosyltransferase activity	1/562	49/18639	0.0204081632653061	0.676846539327475	0.777346077772449	0.958766877994457
GO:0015605	organophosphate ester transmembrane transporter activity	1/562	50/18639	0.02	0.663309608540925	0.784077196884438	0.963833241028801
GO:0032813	tumor necrosis factor receptor superfamily binding	1/562	50/18639	0.02	0.663309608540925	0.784077196884438	0.963833241028801
GO:0008276	protein methyltransferase activity	2/562	95/18639	0.0210526315789474	0.698220640569395	0.785077201339249	0.963833241028801
GO:0003743	translation initiation factor activity	1/562	51/18639	0.0196078431372549	0.650303537785221	0.790605176622506	0.96468338064948
GO:0005010	insulin-like growth factor receptor activity	1/562	51/18639	0.0196078431372549	0.650303537785221	0.790605176622506	0.96468338064948
GO:0005048	signal sequence binding	1/562	51/18639	0.0196078431372549	0.650303537785221	0.790605176622506	0.96468338064948
GO:0016597	amino acid binding	1/562	51/18639	0.0196078431372549	0.650303537785221	0.790605176622506	0.96468338064948
GO:0030594	neurotransmitter receptor activity	2/562	97/18639	0.0206185567010309	0.683824338701985	0.794707392756151	0.966497017163265
GO:0005080	protein kinase C binding	1/562	52/18639	0.0192307692307692	0.637797700520121	0.796936136959183	0.966497017163265
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/562	52/18639	0.0192307692307692	0.637797700520121	0.796936136959183	0.966497017163265
GO:0030159	signaling receptor complex adaptor activity	1/562	52/18639	0.0192307692307692	0.637797700520121	0.796936136959183	0.966497017163265
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	4/562	181/18639	0.0220994475138122	0.732938793967873	0.799141792609142	0.967701290594986
GO:0004864	protein phosphatase inhibitor activity	1/562	53/18639	0.0188679245283019	0.625763781642382	0.803076013810151	0.969522933465205
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/562	53/18639	0.0188679245283019	0.625763781642382	0.803076013810151	0.969522933465205
GO:0030695	GTPase regulator activity	12/562	489/18639	0.0245398773006135	0.813876820295614	0.805278023690344	0.970712783844251
GO:0060589	nucleoside-triphosphatase regulator activity	12/562	490/18639	0.0244897959183673	0.81221584719297	0.807414871308099	0.970836677472129
GO:0017069	snRNA binding	1/562	54/18639	0.0185185185185185	0.61417556346382	0.809030564560108	0.970836677472129
GO:0051287	NAD binding	1/562	54/18639	0.0185185185185185	0.61417556346382	0.809030564560108	0.970836677472129
GO:0008194	UDP-glycosyltransferase activity	3/562	145/18639	0.0206896551724138	0.686182353663026	0.816974108913001	0.978896905274137
GO:0030170	pyridoxal phosphate binding	1/562	56/18639	0.0178571428571429	0.59224072191154	0.820405856641716	0.979004238884219
GO:0015293	symporter activity	3/562	146/18639	0.0205479452054795	0.681482474528348	0.820568852292141	0.979004238884219
GO:0004722	protein serine/threonine phosphatase activity	2/562	103/18639	0.0194174757281553	0.643989911204782	0.821344479091664	0.979004238884219
GO:0015085	calcium ion transmembrane transporter activity	3/562	147/18639	0.0204081632653061	0.676846539327475	0.824103352828823	0.979004238884219
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/562	57/18639	0.0175438596491228	0.581850533807829	0.825837267531635	0.979004238884219
GO:0016504	peptidase activator activity	1/562	57/18639	0.0175438596491228	0.581850533807829	0.825837267531635	0.979004238884219
GO:0070279	vitamin B6 binding	1/562	57/18639	0.0175438596491228	0.581850533807829	0.825837267531635	0.979004238884219
GO:0005085	guanyl-nucleotide exchange factor activity	5/562	230/18639	0.0217391304347826	0.720988704935788	0.826878266927273	0.979004238884219
GO:0017116	single-stranded DNA helicase activity	1/562	58/18639	0.0172413793103448	0.571818628052522	0.831104701373376	0.982550446956968
GO:0004879	nuclear receptor activity	1/562	59/18639	0.0169491525423729	0.562126786899089	0.836213100158595	0.982860526964864
GO:0070888	E-box binding	1/562	59/18639	0.0169491525423729	0.562126786899089	0.836213100158595	0.982860526964864
GO:0004843	cysteine-type deubiquitinase activity	2/562	108/18639	0.0185185185185185	0.61417556346382	0.841129953094097	0.982860526964864
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/562	60/18639	0.0166666666666667	0.552758007117438	0.841167257193626	0.982860526964864
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/562	60/18639	0.0166666666666667	0.552758007117438	0.841167257193626	0.982860526964864
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/562	60/18639	0.0166666666666667	0.552758007117438	0.841167257193626	0.982860526964864
GO:0098531	ligand-modulated transcription factor activity	1/562	60/18639	0.0166666666666667	0.552758007117438	0.841167257193626	0.982860526964864
GO:0051020	GTPase binding	7/562	315/18639	0.0222222222222222	0.737010676156584	0.841220225459903	0.982860526964864
GO:0003774	cytoskeletal motor activity	3/562	153/18639	0.0196078431372549	0.650303537785221	0.844083353060807	0.984089669983864
GO:0015026	coreceptor activity	1/562	61/18639	0.0163934426229508	0.543696400443381	0.845971821565076	0.984089669983864
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/562	61/18639	0.0163934426229508	0.543696400443381	0.845971821565076	0.984089669983864
GO:0016758	hexosyltransferase activity	4/562	197/18639	0.0203045685279188	0.67341077009231	0.848886394057218	0.986042711000961
GO:0016829	lyase activity	4/562	200/18639	0.02	0.663309608540925	0.856955631061256	0.993968886027445
GO:0035091	phosphatidylinositol binding	6/562	284/18639	0.0211267605633803	0.700679163951682	0.861044924674942	0.99726248169899
GO:0101005	deubiquitinase activity	2/562	115/18639	0.0173913043478261	0.576790963948631	0.865498423018972	0.999983397978658
GO:0008168	methyltransferase activity	4/562	204/18639	0.0196078431372549	0.650303537785221	0.867142234186731	0.999983397978658
GO:0008173	RNA methyltransferase activity	1/562	67/18639	0.0149253731343284	0.495007170552929	0.871901003802469	0.999983397978658
GO:0016500	protein-hormone receptor activity	1/562	67/18639	0.0149253731343284	0.495007170552929	0.871901003802469	0.999983397978658
GO:0046873	metal ion transmembrane transporter activity	10/562	450/18639	0.0222222222222222	0.737010676156584	0.875385786997833	0.999983397978658
GO:0015081	sodium ion transmembrane transporter activity	3/562	164/18639	0.0182926829268293	0.606685617567919	0.875637933895932	0.999983397978658
GO:0003777	microtubule motor activity	1/562	68/18639	0.0147058823529412	0.487727653338916	0.875777357230372	0.999983397978658
GO:1990841	promoter-specific chromatin binding	1/562	68/18639	0.0147058823529412	0.487727653338916	0.875777357230372	0.999983397978658
GO:0002039	p53 binding	1/562	69/18639	0.0144927536231884	0.480659136623859	0.879536612264378	0.999983397978658
GO:0140097	catalytic activity, acting on DNA	7/562	336/18639	0.0208333333333333	0.690947508896797	0.883872175178241	0.999983397978658
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	2/562	122/18639	0.0163934426229508	0.543696400443381	0.886395914778746	0.999983397978658
GO:0140299	molecular sensor activity	1/562	71/18639	0.0140845070422535	0.467119442634454	0.886717845800871	0.999983397978658
GO:0003713	transcription coactivator activity	5/562	256/18639	0.01953125	0.647763289590747	0.88847461103197	0.999983397978658
GO:0005267	potassium channel activity	2/562	124/18639	0.0161290322580645	0.534927103662037	0.891790117527197	0.999983397978658
GO:0016741	transferase activity, transferring one-carbon groups	4/562	215/18639	0.0186046511627907	0.617032193991558	0.892000069115482	0.999983397978658
GO:0003678	DNA helicase activity	1/562	74/18639	0.0135135135135135	0.448182167933058	0.896696350649213	0.999983397978658
GO:0003684	damaged DNA binding	1/562	74/18639	0.0135135135135135	0.448182167933058	0.896696350649213	0.999983397978658
GO:0035064	methylated histone binding	1/562	74/18639	0.0135135135135135	0.448182167933058	0.896696350649213	0.999983397978658
GO:0048029	monosaccharide binding	1/562	74/18639	0.0135135135135135	0.448182167933058	0.896696350649213	0.999983397978658
GO:0031490	chromatin DNA binding	2/562	128/18639	0.015625	0.518210631672598	0.9018721417903	0.999983397978658
GO:0140034	methylation-dependent protein binding	1/562	76/18639	0.0131578947368421	0.436387900355872	0.90285626676226	0.999983397978658
GO:0015297	antiporter activity	2/562	135/18639	0.0148148148148148	0.491340450771056	0.91743615831004	0.999983397978658
GO:0016791	phosphatase activity	5/562	273/18639	0.0183150183150183	0.607426381447734	0.917689049770002	0.999983397978658
GO:0099094	ligand-gated monoatomic cation channel activity	2/562	136/18639	0.0147058823529412	0.487727653338916	0.919460548358503	0.999983397978658
GO:0140789	histone phosphatase activity	2/562	136/18639	0.0147058823529412	0.487727653338916	0.919460548358503	0.999983397978658
GO:0140101	catalytic activity, acting on a tRNA	2/562	139/18639	0.0143884892086331	0.477201157223687	0.925257222409734	0.999983397978658
GO:0140767	enzyme-substrate adaptor activity	2/562	139/18639	0.0143884892086331	0.477201157223687	0.925257222409734	0.999983397978658
GO:0020037	heme binding	2/562	142/18639	0.0140845070422535	0.467119442634454	0.93065903989453	0.999983397978658
GO:0046982	protein heterodimerization activity	7/562	369/18639	0.018970189701897	0.62915545525562	0.93135808044874	0.999983397978658
GO:0031267	small GTPase binding	5/562	283/18639	0.0176678445229682	0.585962551714598	0.931529717638037	0.999983397978658
GO:0015291	secondary active transmembrane transporter activity	5/562	287/18639	0.0174216027874564	0.577795826255161	0.936458503787581	0.999983397978658
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/562	91/18639	0.010989010989011	0.36445582886864	0.938755786377981	0.999983397978658
GO:0000510	H3-H4 histone complex chaperone activity	2/562	151/18639	0.0132450331125828	0.439277886450944	0.944734207856542	0.999983397978658
GO:0140584	chromatin extrusion motor activity	2/562	151/18639	0.0132450331125828	0.439277886450944	0.944734207856542	0.999983397978658
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	2/562	151/18639	0.0132450331125828	0.439277886450944	0.944734207856542	0.999983397978658
GO:0140849	ATP-dependent H2AZ histone chaperone activity	2/562	151/18639	0.0132450331125828	0.439277886450944	0.944734207856542	0.999983397978658
GO:0015616	DNA translocase activity	2/562	152/18639	0.0131578947368421	0.436387900355872	0.946118717388121	0.999983397978658
GO:0046906	tetrapyrrole binding	2/562	152/18639	0.0131578947368421	0.436387900355872	0.946118717388121	0.999983397978658
GO:0140674	ATP-dependent histone chaperone activity	2/562	152/18639	0.0131578947368421	0.436387900355872	0.946118717388121	0.999983397978658
GO:0061775	cohesin loader activity	2/562	153/18639	0.0130718954248366	0.433535691856814	0.947470179167291	0.999983397978658
GO:0004386	helicase activity	2/562	155/18639	0.0129032258064516	0.427941682929629	0.950076863663538	0.999983397978658
GO:0005249	voltage-gated potassium channel activity	1/562	98/18639	0.0102040816326531	0.338423269663737	0.950624420266452	0.999983397978658
GO:0043130	ubiquitin binding	1/562	100/18639	0.01	0.331654804270463	0.953572400155317	0.999983397978658
GO:0140658	ATP-dependent chromatin remodeler activity	2/562	158/18639	0.0126582278481013	0.419816207937294	0.95375682358273	0.999983397978658
GO:0003689	DNA clamp loader activity	2/562	160/18639	0.0125	0.414568505338078	0.956064630309915	0.999983397978658
GO:0015079	potassium ion transmembrane transporter activity	2/562	160/18639	0.0125	0.414568505338078	0.956064630309915	0.999983397978658
GO:0140713	histone chaperone activity	2/562	164/18639	0.0121951219512195	0.404457078378613	0.96035406876756	0.999983397978658
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/562	167/18639	0.0119760479041916	0.397191382359835	0.963304712538309	0.999983397978658
GO:0004620	phospholipase activity	1/562	109/18639	0.00917431192660551	0.304270462633452	0.964809285415524	0.999983397978658
GO:1901681	sulfur compound binding	4/562	275/18639	0.0145454545454545	0.482406988029764	0.968036728550579	0.999983397978658
GO:0005244	voltage-gated monoatomic ion channel activity	2/562	173/18639	0.0115606936416185	0.383415958694176	0.968586148655511	0.999983397978658
GO:0016887	ATP hydrolysis activity	7/562	417/18639	0.0167865707434053	0.556734683427635	0.970070886414252	0.999983397978658
GO:0004721	phosphoprotein phosphatase activity	2/562	175/18639	0.0114285714285714	0.379034062023386	0.97017809875334	0.999983397978658
GO:0022832	voltage-gated channel activity	2/562	175/18639	0.0114285714285714	0.379034062023386	0.97017809875334	0.999983397978658
GO:1990782	protein tyrosine kinase binding	1/562	117/18639	0.00854700854700855	0.283465644675609	0.972495604082206	0.999983397978658
GO:0032182	ubiquitin-like protein binding	1/562	120/18639	0.00833333333333333	0.276379003558719	0.974924172882262	0.999983397978658
GO:0008528	G protein-coupled peptide receptor activity	1/562	122/18639	0.00819672131147541	0.271848200221691	0.976423081897448	0.999983397978658
GO:0015276	ligand-gated monoatomic ion channel activity	2/562	186/18639	0.010752688172043	0.356618069108024	0.977635592710405	0.999983397978658
GO:0022834	ligand-gated channel activity	2/562	188/18639	0.0106382978723404	0.352824259862194	0.97878209043187	0.999983397978658
GO:0001653	peptide receptor activity	1/562	128/18639	0.0078125	0.259105315836299	0.98040412238987	0.999983397978658
GO:0035591	signaling adaptor activity	1/562	129/18639	0.00775193798449612	0.257096747496483	0.980999059628101	0.999983397978658
GO:0016298	lipase activity	1/562	130/18639	0.00769230769230769	0.255119080208048	0.981575965543229	0.999983397978658
GO:0004842	ubiquitin-protein transferase activity	7/562	449/18639	0.0155902004454343	0.517056487726779	0.983420482345733	0.999983397978658
GO:0042578	phosphoric ester hydrolase activity	5/562	363/18639	0.0137741046831956	0.45682479927061	0.986091641015857	0.999983397978658
GO:0004713	protein tyrosine kinase activity	1/562	140/18639	0.00714285714285714	0.236896288764616	0.986465546156943	0.999983397978658
GO:0003730	mRNA 3'-UTR binding	3/562	262/18639	0.0114503816793893	0.379757409469995	0.986599903506503	0.999983397978658
GO:0022843	voltage-gated monoatomic cation channel activity	1/562	143/18639	0.00699300699300699	0.231926436552771	0.987662044608984	0.999983397978658
GO:0008094	ATP-dependent activity, acting on DNA	2/562	210/18639	0.00952380952380952	0.315861718352822	0.988173019707726	0.999983397978658
GO:0019787	ubiquitin-like protein transferase activity	7/562	479/18639	0.0146137787056367	0.484672991626981	0.990693891227278	0.999983397978658
GO:0004674	protein serine/threonine kinase activity	6/562	433/18639	0.0138568129330254	0.459567858111496	0.991046113588006	0.999983397978658
GO:0016755	aminoacyltransferase activity	7/562	496/18639	0.0141129032258065	0.468061215704282	0.99335348776937	0.999983397978658
GO:0061630	ubiquitin protein ligase activity	4/562	353/18639	0.0113314447592068	0.375812809371629	0.994439971915822	0.999983397978658
GO:0140030	modification-dependent protein binding	1/562	173/18639	0.00578034682080925	0.191707979347088	0.995114565075235	0.999983397978658
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	2/562	243/18639	0.00823045267489712	0.272966917095031	0.995159396860461	0.999983397978658
GO:0106310	protein serine kinase activity	4/562	361/18639	0.0110803324099723	0.367484547668103	0.995390740778171	0.999983397978658
GO:0004676	3-phosphoinositide-dependent protein kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0004711	ribosomal protein S6 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0035175	histone H3S10 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0035979	histone H2AXS139 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0044022	histone H3S28 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0044023	histone H4S1 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0044024	histone H2AS1 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0044025	histone H2BS14 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0072354	histone H3T3 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0072371	histone H2AS121 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0072518	Rho-dependent protein serine/threonine kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0140823	histone H2BS36 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0140855	histone H3S57 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0140995	histone H2A kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0140997	histone H4 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0140998	histone H2B kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:1990244	histone H2AT120 kinase activity	2/562	245/18639	0.00816326530612245	0.27073861573099	0.995417075766768	0.999983397978658
GO:0004677	DNA-dependent protein kinase activity	2/562	246/18639	0.00813008130081301	0.269638052252409	0.995540823465491	0.999983397978658
GO:0140857	histone H3T45 kinase activity	2/562	246/18639	0.00813008130081301	0.269638052252409	0.995540823465491	0.999983397978658
GO:0035402	histone H3T11 kinase activity	2/562	247/18639	0.00809716599190283	0.268546400218998	0.995661293210967	0.999983397978658
GO:0035403	histone H3T6 kinase activity	2/562	247/18639	0.00809716599190283	0.268546400218998	0.995661293210967	0.999983397978658
GO:0042393	histone binding	2/562	247/18639	0.00809716599190283	0.268546400218998	0.995661293210967	0.999983397978658
GO:0004679	AMP-activated protein kinase activity	2/562	248/18639	0.00806451612903226	0.267463551831018	0.995778569694695	0.999983397978658
GO:0061659	ubiquitin-like protein ligase activity	4/562	372/18639	0.010752688172043	0.356618069108024	0.996445951433201	0.999983397978658
GO:0022836	gated channel activity	3/562	318/18639	0.00943396226415094	0.312881890821191	0.996663316203475	0.999983397978658
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	2/562	268/18639	0.00746268656716418	0.247503585276465	0.997566796993904	0.999983397978658
GO:0001217	DNA-binding transcription repressor activity	2/562	278/18639	0.00719424460431655	0.238600578611844	0.998156318045821	0.999983397978658
GO:0141003	histone H2AX kinase activity	2/562	354/18639	0.00564971751412429	0.18737559563303	0.999783967930435	0.999983397978658
GO:0140996	histone H3 kinase activity	2/562	357/18639	0.00560224089635854	0.185801010795777	0.999801721032101	0.999983397978658
GO:0035173	histone kinase activity	2/562	360/18639	0.00555555555555556	0.184252669039146	0.999818028864952	0.999983397978658
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	3/562	484/18639	0.00619834710743802	0.205571159671774	0.999959226295508	0.999983397978658
GO:0030371	translation repressor activity	1/562	329/18639	0.00303951367781155	0.100806931389198	0.999961454311404	0.999983397978658
GO:0001216	DNA-binding transcription activator activity	3/562	491/18639	0.00610997963340122	0.20264040994122	0.999966365962186	0.999983397978658
GO:0045182	translation regulator activity	1/562	356/18639	0.00280898876404494	0.0931614618737255	0.999983397978658	0.999983397978658