category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 3/7 174/9376 23.0935960591133 HSPH1/HSPA1A/HSP90AA1 8.04059074849044 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 3/7 216/9376 18.6031746031746 APOA1/HSPA1A/HSP90AA1 7.15415218223182 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/7 82/9376 32.6689895470383 HSPA1A/HSP90AA1 7.87277496089499 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 2/7 139/9376 19.2723535457348 HSPA1A/HSP90AA1 5.93231845785552 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 2/7 142/9376 18.8651911468813 KLF2/HSP90AA1 5.86333817112987 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 2/7 187/9376 14.3254392666157 NAMPT/HSP90AA1 5.03102239427487 Organismal Systems Digestive system hsa04977 Vitamin digestion and absorption 1/7 26/9376 51.5164835164835 APOA1 7.05020943961783 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 1/7 37/9376 36.2007722007722 APOA1 5.86395871195378 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/7 362/9376 7.40015785319653 PRL/HSP90AA1 3.39448764785385 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/7 38/9376 35.2481203007519 NAMPT 5.78215384341576 Organismal Systems Digestive system hsa04975 Fat digestion and absorption 1/7 43/9376 31.1495016611296 APOA1 5.4161635700541 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/7 52/9376 25.7582417582418 APOA1 4.89337363294423 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/7 56/9376 23.9183673469388 HSPA1A 4.70173093579129 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 1/7 62/9376 21.6036866359447 HSPA1A 4.44898255369166 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/7 71/9376 18.8651911468813 PRL 4.13015824363711 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/7 76/9376 17.6240601503759 APOA1 3.97731934187549 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/7 94/9376 14.2492401215805 HSP90AA1 3.5287602654778 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/7 106/9376 12.6361185983827 HSP90AA1 3.2931327906014 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/7 109/9376 12.2883355176933 HSP90AA1 3.24012388374589 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/7 110/9376 12.1766233766234 HSP90AA1 3.22291498675069 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/7 112/9376 11.9591836734694 HSPA1A 3.18915760772773 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/7 133/9376 10.0708915145005 KLF2 2.87976703259153 Human Diseases Infectious disease: viral hsa05162 Measles 1/7 136/9376 9.84873949579832 HSPA1A 2.84120726894236 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/7 140/9376 9.56734693877551 KLF2 2.79162094867456 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/7 168/9376 7.97278911564626 HSP90AA1 2.49268014798942 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/7 168/9376 7.97278911564626 PRL 2.49268014798942 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/7 217/9376 6.1724818959842 HSP90AA1 2.10713739941738 NA NA hsa04081 Hormone signaling 1/7 219/9376 6.11611219830398 PRL 2.09398491742935 Genetic Information Processing Transcription hsa03040 Spliceosome 1/7 243/9376 5.51205173427396 HSPA1A 1.94786348920636 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/7 248/9376 5.40092165898618 HSP90AA1 1.91986062301137 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/7 250/9376 5.35771428571429 HSPA1A 1.90887092525785 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/7 275/9376 4.87064935064935 HSPA1A 1.78071188785521 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/7 298/9376 4.49472674976031 PRL 1.67576959281918 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/7 300/9376 4.4647619047619 HSPA1A 1.66715054274408 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/7 370/9376 3.62007722007722 PRL 1.40551997039367