ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0022853	active monoatomic ion transmembrane transporter activity	21/556	118/18639	0.177966101694915	5.96602548469699	4.11827048407749e-11	3.60760494405188e-08
GO:0042625	ATPase-coupled ion transmembrane transporter activity	10/556	24/18639	0.416666666666667	13.9680755395683	6.93027740625972e-10	1.51773075197088e-07
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	10/556	24/18639	0.416666666666667	13.9680755395683	6.93027740625972e-10	1.51773075197088e-07
GO:0046961	proton-transporting ATPase activity, rotational mechanism	10/556	24/18639	0.416666666666667	13.9680755395683	6.93027740625972e-10	1.51773075197088e-07
GO:0015399	primary active transmembrane transporter activity	23/556	166/18639	0.13855421686747	4.64480584207333	8.93531371149487e-10	1.5654669622539e-07
GO:0030695	GTPase regulator activity	41/556	489/18639	0.0838445807770961	2.810753850907	2.75159299735415e-09	3.6548900682053e-07
GO:0060589	nucleoside-triphosphatase regulator activity	41/556	490/18639	0.0836734693877551	2.80501761855821	2.92057425541519e-09	3.6548900682053e-07
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	13/556	54/18639	0.240740740740741	8.07044364508393	4.65413047180508e-09	5.09627286662656e-07
GO:0015078	proton transmembrane transporter activity	23/556	185/18639	0.124324324324324	4.1677717285631	7.56309035212669e-09	7.36140794273665e-07
GO:0005096	GTPase activator activity	28/556	271/18639	0.103321033210332	3.4636703920996	1.18836527239438e-08	1.04100797861747e-06
GO:0042626	ATPase-coupled transmembrane transporter activity	15/556	98/18639	0.153061224489796	5.13112979004551	2.03639438655638e-07	1.62171043874853e-05
GO:0031625	ubiquitin protein ligase binding	26/556	302/18639	0.0860927152317881	2.88611891943399	1.41139286942703e-06	0.000103031679468174
GO:0022804	active transmembrane transporter activity	33/556	457/18639	0.0722100656455142	2.42072556396896	2.90810319829921e-06	0.000195961415516162
GO:0044389	ubiquitin-like protein ligase binding	26/556	322/18639	0.0807453416149068	2.70685687474865	4.60363608479614e-06	0.000279356740935089
GO:0001618	virus receptor activity	12/556	81/18639	0.148148148148148	4.96642685851319	4.7835058379296e-06	0.000279356740935089
GO:0140272	exogenous protein binding	12/556	82/18639	0.146341463414634	4.90586067731181	5.45390859406915e-06	0.000298601495525286
GO:0042277	peptide binding	21/556	249/18639	0.0843373493975904	2.82727312126203	1.96799318117419e-05	0.00101409530982858
GO:0031072	heat shock protein binding	13/556	131/18639	0.099236641221374	3.32674776209567	0.000150337939277965	0.00731644637819431
GO:0005085	guanyl-nucleotide exchange factor activity	18/556	230/18639	0.0782608695652174	2.62356897091023	0.000195900808461296	0.0090320583269524
GO:0042608	T cell receptor binding	4/556	11/18639	0.363636363636364	12.190320470896	0.000218712362488282	0.00957960147698675
GO:0005543	phospholipid binding	29/556	497/18639	0.0583501006036217	1.95609267113472	0.000485384965630882	0.0202474871377453
GO:0043394	proteoglycan binding	6/556	37/18639	0.162162162162162	5.43622399377795	0.00072545645964028	0.0288863572111312
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	8/556	68/18639	0.117647058823529	3.94392721117224	0.000913890355457906	0.0339160633840199
GO:0035091	phosphatidylinositol binding	19/556	284/18639	0.0669014084507042	2.24276142466309	0.000929207216000546	0.0339160633840199
GO:0023026	MHC class II protein complex binding	5/556	27/18639	0.185185185185185	6.20803357314149	0.00108665321529281	0.0374198243176811
GO:0140662	ATP-dependent protein folding chaperone	6/556	40/18639	0.15	5.0285071942446	0.00111063405509099	0.0374198243176811
GO:0017080	sodium channel regulator activity	6/556	41/18639	0.146341463414634	4.90586067731181	0.00126871718226218	0.0411628241356173
GO:0038191	neuropilin binding	4/556	17/18639	0.235294117647059	7.88785442234448	0.00136785041713519	0.0427941773360868
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	4/556	18/18639	0.222222222222222	7.44964028776978	0.00171753089183914	0.0490356515626307
GO:0044183	protein folding chaperone	8/556	75/18639	0.106666666666667	3.5758273381295	0.00173971389813345	0.0490356515626307
GO:0001968	fibronectin binding	5/556	30/18639	0.166666666666667	5.58723021582734	0.0017820771796583	0.0490356515626307
GO:0004879	nuclear receptor activity	7/556	59/18639	0.11864406779661	3.97735032313133	0.00180244664858361	0.0490356515626307
GO:0001223	transcription coactivator binding	6/556	44/18639	0.136363636363636	4.571370176586	0.00184723344927718	0.0490356515626307
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	21/556	349/18639	0.0601719197707736	2.01716620972563	0.00193865886392279	0.0497835196283261
GO:0098531	ligand-modulated transcription factor activity	7/556	60/18639	0.116666666666667	3.91106115107914	0.00198906756505869	0.0497835196283261
GO:0042605	peptide antigen binding	6/556	45/18639	0.133333333333333	4.46978417266187	0.0020786180513243	0.0505797059155579
GO:0044325	transmembrane transporter binding	11/556	136/18639	0.0808823529411765	2.71144995768091	0.0025550026285657	0.0604914135844204
GO:0140311	protein sequestering activity	5/556	33/18639	0.151515151515152	5.07930019620667	0.00275784899389715	0.0635756768066816
GO:0038187	pattern recognition receptor activity	6/556	48/18639	0.125	4.1904226618705	0.00290492315486726	0.063617817091593
GO:0140693	molecular condensate scaffold activity	6/556	48/18639	0.125	4.1904226618705	0.00290492315486726	0.063617817091593
GO:0001540	amyloid-beta binding	8/556	83/18639	0.0963855421686747	3.23116928144232	0.00330779775920939	0.070673922855303
GO:0051117	ATPase binding	8/556	84/18639	0.0952380952380952	3.19270298047276	0.00356291398528882	0.0743122059788812
GO:0050840	extracellular matrix binding	7/556	67/18639	0.104477611940299	3.50244282186191	0.00374726683541067	0.0763396685539475
GO:0019955	cytokine binding	11/556	144/18639	0.0763888888888889	2.56081384892086	0.00396957796158428	0.0790306885079052
GO:0023023	MHC protein complex binding	5/556	37/18639	0.135135135135135	4.53018666148163	0.00459405336396277	0.0894309054851419
GO:0035259	nuclear glucocorticoid receptor binding	3/556	12/18639	0.25	8.38084532374101	0.00474966365164316	0.0904501164965088
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/556	89/18639	0.0898876404494382	3.01333764449115	0.00507463970993121	0.0925596840102134
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/556	89/18639	0.0898876404494382	3.01333764449115	0.00507463970993121	0.0925596840102134
GO:0005315	phosphate transmembrane transporter activity	4/556	24/18639	0.166666666666667	5.58723021582734	0.00517742524714664	0.0925596840102134
GO:0140793	histone H2AXY142 phosphatase activity	8/556	90/18639	0.0888888888888889	2.97985611510791	0.00542830883455961	0.0951039707814843
GO:0140313	molecular sequestering activity	6/556	55/18639	0.109090909090909	3.6570961412688	0.00576176749373905	0.0985341195172058
GO:0019207	kinase regulator activity	17/556	287/18639	0.0592334494773519	1.98570551224526	0.00584905732293916	0.0985341195172058
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/556	41/18639	0.121951219512195	4.08821723109317	0.00716589682768522	0.109088147830148
GO:0008137	NADH dehydrogenase (ubiquinone) activity	5/556	41/18639	0.121951219512195	4.08821723109317	0.00716589682768522	0.109088147830148
GO:0016887	ATP hydrolysis activity	22/556	417/18639	0.052757793764988	1.76861963666477	0.00732036999173561	0.109088147830148
GO:0061980	regulatory RNA binding	6/556	58/18639	0.103448275862069	3.46793599603076	0.00746571571760277	0.109088147830148
GO:0005161	platelet-derived growth factor receptor binding	3/556	14/18639	0.214285714285714	7.18358170606372	0.00751754060749323	0.109088147830148
GO:0005545	1-phosphatidylinositol binding	3/556	14/18639	0.214285714285714	7.18358170606372	0.00751754060749323	0.109088147830148
GO:0001221	transcription coregulator binding	9/556	115/18639	0.0782608695652174	2.62356897091023	0.00752471708588189	0.109088147830148
GO:0017124	SH3 domain binding	9/556	115/18639	0.0782608695652174	2.62356897091023	0.00752471708588189	0.109088147830148
GO:0035198	miRNA binding	5/556	42/18639	0.119047619047619	3.99087872559096	0.0079392028869022	0.109088147830148
GO:0009055	electron transfer activity	9/556	116/18639	0.0775862068965517	2.60095199702307	0.0079488877026536	0.109088147830148
GO:0001671	ATPase activator activity	4/556	27/18639	0.148148148148148	4.96642685851319	0.00796991034375511	0.109088147830148
GO:0015252	proton channel activity	4/556	27/18639	0.148148148148148	4.96642685851319	0.00796991034375511	0.109088147830148
GO:0004725	protein tyrosine phosphatase activity	8/556	98/18639	0.0816326530612245	2.73660255469094	0.00897467399639575	0.115022279104417
GO:0005178	integrin binding	11/556	161/18639	0.0683229813664596	2.29041735555655	0.00902524131673564	0.115022279104417
GO:0045499	chemorepellent activity	4/556	28/18639	0.142857142857143	4.78905447070915	0.00908309559825067	0.115022279104417
GO:0051019	mitogen-activated protein kinase binding	4/556	28/18639	0.142857142857143	4.78905447070915	0.00908309559825067	0.115022279104417
GO:0004129	cytochrome-c oxidase activity	3/556	15/18639	0.2	6.70467625899281	0.00919127801062697	0.115022279104417
GO:0140776	protein-containing complex destabilizing activity	3/556	15/18639	0.2	6.70467625899281	0.00919127801062697	0.115022279104417
GO:0003954	NADH dehydrogenase activity	5/556	44/18639	0.113636363636364	3.809475147155	0.009655938848671	0.11913524551318
GO:0019887	protein kinase regulator activity	15/556	255/18639	0.0588235294117647	1.97196360558612	0.00986169600090106	0.119983968010963
GO:0051082	unfolded protein binding	9/556	121/18639	0.0743801652892562	2.49347464177418	0.0103486167822077	0.124183401386493
GO:0008234	cysteine-type peptidase activity	12/556	187/18639	0.0641711229946524	2.15123302427577	0.0105323233808421	0.124679936238077
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/556	16/18639	0.1875	6.28563399280576	0.0110651695533033	0.129241180382582
GO:0045296	cadherin binding	18/556	334/18639	0.0538922155688623	1.80664929134537	0.0117983121501273	0.135991071625151
GO:0141108	transporter regulator activity	11/556	170/18639	0.0647058823529412	2.16915996614473	0.0132077141886246	0.150259189990067
GO:0042826	histone deacetylase binding	9/556	127/18639	0.0708661417322835	2.3756726901943	0.0139038210781299	0.154811635431182
GO:0051020	GTPase binding	17/556	315/18639	0.053968253968254	1.80919835560123	0.013961323286602	0.154811635431182
GO:0120015	sterol transfer activity	4/556	32/18639	0.125	4.1904226618705	0.0145304945298733	0.159108915102112
GO:0060590	ATPase regulator activity	5/556	49/18639	0.102040816326531	3.42075319336368	0.0150247699873295	0.162490105048156
GO:0004843	cysteine-type deubiquitinase activity	8/556	108/18639	0.0740740740740741	2.48321342925659	0.0155488102113885	0.166106801770444
GO:0004197	cysteine-type endopeptidase activity	7/556	88/18639	0.0795454545454545	2.6666326030085	0.0160847726476988	0.168466351804171
GO:0140416	transcription regulator inhibitor activity	4/556	33/18639	0.121212121212121	4.06344015696534	0.0161543077072493	0.168466351804171
GO:0043395	heparan sulfate proteoglycan binding	3/556	19/18639	0.157894736842105	5.2931654676259	0.0179227158723055	0.183014035740153
GO:0097110	scaffold protein binding	6/556	70/18639	0.0857142857142857	2.87343268242549	0.0179671313626177	0.183014035740153
GO:0001217	DNA-binding transcription repressor activity	15/556	278/18639	0.0539568345323741	1.80881553749806	0.0201660180283589	0.199878088689042
GO:0005518	collagen binding	6/556	72/18639	0.0833333333333333	2.79361510791367	0.0203802643403119	0.199878088689042
GO:0005246	calcium channel regulator activity	5/556	53/18639	0.0943396226415094	3.16258314103434	0.020535420070792	0.199878088689042
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/556	53/18639	0.0943396226415094	3.16258314103434	0.020535420070792	0.199878088689042
GO:0140789	histone phosphatase activity	9/556	136/18639	0.0661764705882353	2.21845905628438	0.0208268707852697	0.200487239647212
GO:0101005	deubiquitinase activity	8/556	115/18639	0.0695652173913043	2.33206130747576	0.0218629223871214	0.206419607560414
GO:0099106	ion channel regulator activity	10/556	160/18639	0.0625	2.09521133093525	0.0219144103916878	0.206419607560414
GO:0061135	endopeptidase regulator activity	11/556	184/18639	0.0597826086956522	2.00411518611198	0.0224330784247151	0.209057198936707
GO:0031267	small GTPase binding	15/556	283/18639	0.0530035335689046	1.77685766581081	0.0232182784126269	0.212034768257143
GO:1901981	phosphatidylinositol phosphate binding	11/556	185/18639	0.0594594594594595	1.99328213105192	0.0232366869322896	0.212034768257143
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/556	21/18639	0.142857142857143	4.78905447070915	0.0235441818380187	0.212625807114478
GO:0003725	double-stranded RNA binding	6/556	75/18639	0.08	2.68187050359712	0.024397660839937	0.218085213222294
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/556	22/18639	0.136363636363636	4.571370176586	0.0266718076975396	0.231331718247967
GO:0031683	G-protein beta/gamma-subunit complex binding	3/556	22/18639	0.136363636363636	4.571370176586	0.0266718076975396	0.231331718247967
GO:0061133	endopeptidase activator activity	3/556	22/18639	0.136363636363636	4.571370176586	0.0266718076975396	0.231331718247967
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/556	58/18639	0.0862068965517241	2.88994666335897	0.0290859333469104	0.249796839332289
GO:0016247	channel regulator activity	10/556	168/18639	0.0595238095238095	1.99543936279548	0.0294286020686591	0.250285974875198
GO:0042171	lysophosphatidic acid acyltransferase activity	3/556	23/18639	0.130434782608696	4.37261495151705	0.0300100027278359	0.250369165615088
GO:0071617	lysophospholipid acyltransferase activity	3/556	23/18639	0.130434782608696	4.37261495151705	0.0300100027278359	0.250369165615088
GO:0031593	polyubiquitin modification-dependent protein binding	5/556	59/18639	0.0847457627118644	2.84096451652238	0.031028441942192	0.256423727748681
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/556	24/18639	0.125	4.1904226618705	0.0335575137965057	0.266758082801719
GO:0030215	semaphorin receptor binding	3/556	24/18639	0.125	4.1904226618705	0.0335575137965057	0.266758082801719
GO:0005031	tumor necrosis factor receptor activity	2/556	10/18639	0.2	6.70467625899281	0.0341060562486217	0.266758082801719
GO:0005528	FK506 binding	2/556	10/18639	0.2	6.70467625899281	0.0341060562486217	0.266758082801719
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/556	10/18639	0.2	6.70467625899281	0.0341060562486217	0.266758082801719
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/556	10/18639	0.2	6.70467625899281	0.0341060562486217	0.266758082801719
GO:0051879	Hsp90 protein binding	4/556	42/18639	0.0952380952380952	3.19270298047276	0.0358812990002913	0.271122075608865
GO:0019783	ubiquitin-like protein peptidase activity	8/556	127/18639	0.062992125984252	2.11170905795049	0.036561712726354	0.271122075608865
GO:0140297	DNA-binding transcription factor binding	22/556	488/18639	0.0450819672131148	1.51129997641231	0.0365994879655628	0.271122075608865
GO:0005126	cytokine receptor binding	14/556	275/18639	0.0509090909090909	1.70664486592544	0.0370325822722615	0.271122075608865
GO:0003707	nuclear steroid receptor activity	3/556	25/18639	0.12	4.02280575539568	0.0373125585505789	0.271122075608865
GO:0005537	D-mannose binding	3/556	25/18639	0.12	4.02280575539568	0.0373125585505789	0.271122075608865
GO:0015662	P-type ion transporter activity	3/556	25/18639	0.12	4.02280575539568	0.0373125585505789	0.271122075608865
GO:0140358	P-type transmembrane transporter activity	3/556	25/18639	0.12	4.02280575539568	0.0373125585505789	0.271122075608865
GO:0141003	histone H2AX kinase activity	17/556	354/18639	0.0480225988700565	1.60987989269601	0.0374495104436902	0.271122075608865
GO:0061134	peptidase regulator activity	12/556	226/18639	0.0530973451327434	1.78000254663526	0.0390821540291118	0.280622679750016
GO:0140996	histone H3 kinase activity	17/556	357/18639	0.0476190476190476	1.59635149023638	0.0400293525875453	0.284685310033074
GO:0008199	ferric iron binding	2/556	11/18639	0.181818181818182	6.09516023544801	0.0408757721561782	0.284685310033074
GO:0019864	IgG binding	2/556	11/18639	0.181818181818182	6.09516023544801	0.0408757721561782	0.284685310033074
GO:0015216	purine nucleotide transmembrane transporter activity	3/556	26/18639	0.115384615384615	3.86808245711123	0.0412728702901831	0.284685310033074
GO:0030247	polysaccharide binding	3/556	26/18639	0.115384615384615	3.86808245711123	0.0412728702901831	0.284685310033074
GO:0003712	transcription coregulator activity	22/556	495/18639	0.0444444444444444	1.48992805755396	0.0417093678419872	0.2854484861686
GO:0035173	histone kinase activity	17/556	360/18639	0.0472222222222222	1.58304856115108	0.0427354504694131	0.288159470757648
GO:0003714	transcription corepressor activity	11/556	204/18639	0.053921568627451	1.80763330512061	0.0427633917791031	0.288159470757648
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/556	45/18639	0.0888888888888889	2.97985611510791	0.0445831541073714	0.295870022712556
GO:0008009	chemokine activity	4/556	45/18639	0.0888888888888889	2.97985611510791	0.0445831541073714	0.295870022712556
GO:0042578	phosphoric ester hydrolase activity	17/556	363/18639	0.046831955922865	1.56996551519115	0.0455706138855984	0.300149306494618
GO:0016651	oxidoreductase activity, acting on NAD(P)H	6/556	88/18639	0.0681818181818182	2.285685088293	0.0477863875678693	0.301080291222497
GO:0005527	macrolide binding	2/556	12/18639	0.166666666666667	5.58723021582734	0.0481009938570852	0.301080291222497
GO:0035497	cAMP response element binding	2/556	12/18639	0.166666666666667	5.58723021582734	0.0481009938570852	0.301080291222497
GO:0046875	ephrin receptor binding	3/556	28/18639	0.107142857142857	3.59179085303186	0.049798057645715	0.301080291222497
GO:0061749	forked DNA-dependent helicase activity	4/556	47/18639	0.0851063829787234	2.85305372723098	0.0509827471478203	0.301080291222497
GO:1990518	single-stranded 3'-5' DNA helicase activity	4/556	47/18639	0.0851063829787234	2.85305372723098	0.0509827471478203	0.301080291222497
GO:0002020	protease binding	8/556	136/18639	0.0588235294117647	1.97196360558612	0.0511805227190371	0.301080291222497
GO:0046982	protein heterodimerization activity	17/556	369/18639	0.046070460704607	1.5444376206352	0.0516387632396952	0.301080291222497
GO:0032934	sterol binding	5/556	68/18639	0.0735294117647059	2.46495450698265	0.0521546450161768	0.301080291222497
GO:0043236	laminin binding	3/556	29/18639	0.103448275862069	3.46793599603076	0.0543563468997114	0.301080291222497
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/556	29/18639	0.103448275862069	3.46793599603076	0.0543563468997114	0.301080291222497
GO:0051861	glycolipid binding	3/556	29/18639	0.103448275862069	3.46793599603076	0.0543563468997114	0.301080291222497
GO:0009378	four-way junction helicase activity	4/556	48/18639	0.0833333333333333	2.79361510791367	0.0543610819385776	0.301080291222497
GO:0036121	double-stranded DNA helicase activity	4/556	48/18639	0.0833333333333333	2.79361510791367	0.0543610819385776	0.301080291222497
GO:0043138	3'-5' DNA helicase activity	4/556	48/18639	0.0833333333333333	2.79361510791367	0.0543610819385776	0.301080291222497
GO:0019001	guanyl nucleotide binding	18/556	400/18639	0.045	1.50855215827338	0.0555573720193802	0.301080291222497
GO:0032561	guanyl ribonucleotide binding	18/556	400/18639	0.045	1.50855215827338	0.0555573720193802	0.301080291222497
GO:0005035	death receptor activity	2/556	13/18639	0.153846153846154	5.15744327614831	0.0557486274564348	0.301080291222497
GO:0005172	vascular endothelial growth factor receptor binding	2/556	13/18639	0.153846153846154	5.15744327614831	0.0557486274564348	0.301080291222497
GO:0008035	high-density lipoprotein particle binding	2/556	13/18639	0.153846153846154	5.15744327614831	0.0557486274564348	0.301080291222497
GO:0017154	semaphorin receptor activity	2/556	13/18639	0.153846153846154	5.15744327614831	0.0557486274564348	0.301080291222497
GO:0031432	titin binding	2/556	13/18639	0.153846153846154	5.15744327614831	0.0557486274564348	0.301080291222497
GO:0031994	insulin-like growth factor I binding	2/556	13/18639	0.153846153846154	5.15744327614831	0.0557486274564348	0.301080291222497
GO:0035325	Toll-like receptor binding	2/556	13/18639	0.153846153846154	5.15744327614831	0.0557486274564348	0.301080291222497
GO:0043178	alcohol binding	6/556	92/18639	0.0652173913043478	2.18630747575852	0.057057147492422	0.301080291222497
GO:0001965	G-protein alpha-subunit binding	3/556	30/18639	0.1	3.3523381294964	0.0591068033303898	0.301080291222497
GO:0015215	nucleotide transmembrane transporter activity	3/556	30/18639	0.1	3.3523381294964	0.0591068033303898	0.301080291222497
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/556	30/18639	0.1	3.3523381294964	0.0591068033303898	0.301080291222497
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	13/556	268/18639	0.0485074626865672	1.62613416729303	0.0592656435874292	0.301080291222497
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	12/556	243/18639	0.0493827160493827	1.6554756195044	0.0612139349492969	0.301080291222497
GO:0015605	organophosphate ester transmembrane transporter activity	4/556	50/18639	0.08	2.68187050359712	0.0614716447476141	0.301080291222497
GO:0005525	GTP binding	17/556	378/18639	0.044973544973545	1.50766529633436	0.0617718040800768	0.301080291222497
GO:0005347	ATP transmembrane transporter activity	2/556	14/18639	0.142857142857143	4.78905447070915	0.0637871419312583	0.301080291222497
GO:0008559	ABC-type xenobiotic transporter activity	2/556	14/18639	0.142857142857143	4.78905447070915	0.0637871419312583	0.301080291222497
GO:0071933	Arp2/3 complex binding	2/556	14/18639	0.142857142857143	4.78905447070915	0.0637871419312583	0.301080291222497
GO:0016411	acylglycerol O-acyltransferase activity	3/556	31/18639	0.0967741935483871	3.24419818983523	0.0640453262405216	0.301080291222497
GO:0070325	lipoprotein particle receptor binding	3/556	31/18639	0.0967741935483871	3.24419818983523	0.0640453262405216	0.301080291222497
GO:0004676	3-phosphoinositide-dependent protein kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0004711	ribosomal protein S6 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0035175	histone H3S10 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0035979	histone H2AXS139 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0044022	histone H3S28 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0044023	histone H4S1 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0044024	histone H2AS1 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0044025	histone H2BS14 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0072354	histone H3T3 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0072371	histone H2AS121 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0072518	Rho-dependent protein serine/threonine kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0140823	histone H2BS36 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0140855	histone H3S57 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0140995	histone H2A kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0140997	histone H4 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0140998	histone H2B kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:1990244	histone H2AT120 kinase activity	12/556	245/18639	0.0489795918367347	1.64196153281456	0.064271706002976	0.301080291222497
GO:0004677	DNA-dependent protein kinase activity	12/556	246/18639	0.0487804878048781	1.63528689243727	0.0658376328737543	0.304476251178269
GO:0140857	histone H3T45 kinase activity	12/556	246/18639	0.0487804878048781	1.63528689243727	0.0658376328737543	0.304476251178269
GO:0004896	cytokine receptor activity	6/556	96/18639	0.0625	2.09521133093525	0.0673347225645805	0.304476251178269
GO:0033218	amide binding	12/556	247/18639	0.048582995951417	1.62866629773105	0.0674283759442018	0.304476251178269
GO:0035402	histone H3T11 kinase activity	12/556	247/18639	0.048582995951417	1.62866629773105	0.0674283759442018	0.304476251178269
GO:0035403	histone H3T6 kinase activity	12/556	247/18639	0.048582995951417	1.62866629773105	0.0674283759442018	0.304476251178269
GO:0004679	AMP-activated protein kinase activity	12/556	248/18639	0.0483870967741935	1.62209909491761	0.0690440196363224	0.304476251178269
GO:0005080	protein kinase C binding	4/556	52/18639	0.0769230769230769	2.57872163807416	0.06904812429018	0.304476251178269
GO:0030159	signaling receptor complex adaptor activity	4/556	52/18639	0.0769230769230769	2.57872163807416	0.06904812429018	0.304476251178269
GO:0051059	NF-kappaB binding	3/556	32/18639	0.09375	3.14281699640288	0.0691675502105885	0.304476251178269
GO:0071813	lipoprotein particle binding	3/556	32/18639	0.09375	3.14281699640288	0.0691675502105885	0.304476251178269
GO:0071814	protein-lipid complex binding	3/556	32/18639	0.09375	3.14281699640288	0.0691675502105885	0.304476251178269
GO:0017081	chloride channel regulator activity	2/556	15/18639	0.133333333333333	4.46978417266187	0.0721865056113555	0.314603875201728
GO:0120283	protein serine/threonine kinase binding	2/556	15/18639	0.133333333333333	4.46978417266187	0.0721865056113555	0.314603875201728
GO:0140296	general transcription initiation factor binding	4/556	53/18639	0.0754716981132075	2.53006651282747	0.0730083450427832	0.315894573315456
GO:0019003	GDP binding	5/556	75/18639	0.0666666666666667	2.23489208633094	0.0732038794326913	0.315894573315456
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/556	33/18639	0.0909090909090909	3.047580117724	0.0744688744609225	0.316673466154214
GO:0019956	chemokine binding	3/556	33/18639	0.0909090909090909	3.047580117724	0.0744688744609225	0.316673466154214
GO:0071889	14-3-3 protein binding	3/556	33/18639	0.0909090909090909	3.047580117724	0.0744688744609225	0.316673466154214
GO:0106310	protein serine kinase activity	16/556	361/18639	0.0443213296398892	1.4858008330178	0.0756532486824654	0.320155777033042
GO:0043130	ubiquitin binding	6/556	100/18639	0.06	2.01140287769784	0.0786197283170501	0.331110009642961
GO:0004721	phosphoprotein phosphatase activity	9/556	175/18639	0.0514285714285714	1.72405960945529	0.0793459143255481	0.332569478225742
GO:0008142	oxysterol binding	2/556	16/18639	0.125	4.1904226618705	0.0809181250482201	0.332790035409581
GO:0015385	sodium:proton antiporter activity	2/556	16/18639	0.125	4.1904226618705	0.0809181250482201	0.332790035409581
GO:0015562	efflux transmembrane transporter activity	2/556	16/18639	0.125	4.1904226618705	0.0809181250482201	0.332790035409581
GO:0015923	mannosidase activity	2/556	16/18639	0.125	4.1904226618705	0.0809181250482201	0.332790035409581
GO:0004519	endonuclease activity	7/556	127/18639	0.0551181102362205	1.84774542570668	0.0859881080595295	0.351988704019383
GO:0003774	cytoskeletal motor activity	8/556	153/18639	0.0522875816993464	1.75285653829877	0.087941452325397	0.358219101601683
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/556	17/18639	0.117647058823529	3.94392721117224	0.0899547861865089	0.358219101601683
GO:0008484	sulfuric ester hydrolase activity	2/556	17/18639	0.117647058823529	3.94392721117224	0.0899547861865089	0.358219101601683
GO:0019198	transmembrane receptor protein phosphatase activity	2/556	17/18639	0.117647058823529	3.94392721117224	0.0899547861865089	0.358219101601683
GO:0048038	quinone binding	2/556	17/18639	0.117647058823529	3.94392721117224	0.0899547861865089	0.358219101601683
GO:0016504	peptidase activator activity	4/556	57/18639	0.0701754385964912	2.35251798561151	0.0899637013154913	0.358219101601683
GO:0035591	signaling adaptor activity	7/556	129/18639	0.0542635658914729	1.81909820980425	0.0915873857433979	0.363034162494193
GO:0005516	calmodulin binding	10/556	207/18639	0.0483091787439614	1.61948701908039	0.092096325767684	0.36340712329951
GO:0017116	single-stranded DNA helicase activity	4/556	58/18639	0.0689655172413793	2.31195733068717	0.09447316560946	0.371114318716982
GO:0140375	immune receptor activity	8/556	156/18639	0.0512820512820513	1.7191477587161	0.0956964148868452	0.374241336789627
GO:0051015	actin filament binding	10/556	209/18639	0.0478468899521531	1.60398953564421	0.0965829366047228	0.376029566514387
GO:0070888	E-box binding	4/556	59/18639	0.0677966101694915	2.2727716132179	0.0990873273307161	0.379742548619142
GO:0004674	protein serine/threonine kinase activity	18/556	433/18639	0.0415704387990762	1.3935816704604	0.0991211034719611	0.379742548619142
GO:0000900	mRNA regulatory element binding translation repressor activity	2/556	18/18639	0.111111111111111	3.72482014388489	0.0992705977554605	0.379742548619142
GO:0035615	clathrin adaptor activity	2/556	18/18639	0.111111111111111	3.72482014388489	0.0992705977554605	0.379742548619142
GO:0001216	DNA-binding transcription activator activity	20/556	491/18639	0.0407331975560081	1.36551451303316	0.0997581832055716	0.379948558643829
GO:0030165	PDZ domain binding	5/556	83/18639	0.0602409638554217	2.01948080090145	0.102109983272818	0.387222274229386
GO:0000146	microfilament motor activity	3/556	38/18639	0.0789473684210526	2.64658273381295	0.103487828833498	0.389078704112205
GO:0043531	ADP binding	3/556	38/18639	0.0789473684210526	2.64658273381295	0.103487828833498	0.389078704112205
GO:0005496	steroid binding	6/556	108/18639	0.0555555555555556	1.86241007194245	0.104162618904016	0.389942111794521
GO:0051087	protein-folding chaperone binding	7/556	134/18639	0.0522388059701493	1.75122141093096	0.106454979295566	0.396827922820917
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/556	19/18639	0.105263157894737	3.52877697841727	0.108840936800538	0.402298146148822
GO:0005520	insulin-like growth factor binding	2/556	19/18639	0.105263157894737	3.52877697841727	0.108840936800538	0.402298146148822
GO:0004866	endopeptidase inhibitor activity	8/556	161/18639	0.0496894409937888	1.6657580767684	0.109456375765294	0.402873046934444
GO:0140597	protein carrier chaperone	9/556	188/18639	0.0478723404255319	1.60484272156743	0.110713624856447	0.405795545498944
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	5/556	86/18639	0.0581395348837209	1.94903379621884	0.114218530331226	0.416897635708976
GO:0003779	actin binding	18/556	443/18639	0.0406320541760722	1.3621238449421	0.115685219193929	0.417065856923494
GO:0016922	nuclear receptor binding	7/556	137/18639	0.0510948905109489	1.71287349682298	0.115960770294386	0.417065856923494
GO:0061791	GTPase motor activity	3/556	40/18639	0.075	2.5142535971223	0.116169028640791	0.417065856923494
GO:1990606	membrane scission GTPase motor activity	3/556	40/18639	0.075	2.5142535971223	0.116169028640791	0.417065856923494
GO:0016791	phosphatase activity	12/556	273/18639	0.043956043956044	1.47355522175666	0.117654292784768	0.420674124405947
GO:0140713	histone chaperone activity	8/556	164/18639	0.0487804878048781	1.63528689243727	0.118205371284038	0.420926444084625
GO:0004857	enzyme inhibitor activity	17/556	416/18639	0.0408653846153846	1.3699458702269	0.119153247996989	0.422583988847621
GO:0003924	GTPase activity	14/556	331/18639	0.0422960725075529	1.41790736595014	0.121198269996082	0.423230862657921
GO:0030295	protein kinase activator activity	7/556	139/18639	0.0503597122302158	1.68822783499819	0.122536110284605	0.423230862657921
GO:0070851	growth factor receptor binding	7/556	139/18639	0.0503597122302158	1.68822783499819	0.122536110284605	0.423230862657921
GO:0001530	lipopolysaccharide binding	3/556	41/18639	0.0731707317073171	2.4529303386559	0.12271762456063	0.423230862657921
GO:0001727	lipid kinase activity	3/556	41/18639	0.0731707317073171	2.4529303386559	0.12271762456063	0.423230862657921
GO:0042169	SH2 domain binding	3/556	41/18639	0.0731707317073171	2.4529303386559	0.12271762456063	0.423230862657921
GO:0042287	MHC protein binding	3/556	41/18639	0.0731707317073171	2.4529303386559	0.12271762456063	0.423230862657921
GO:0001846	opsonin binding	2/556	21/18639	0.0952380952380952	3.19270298047276	0.128652734640474	0.434299124576278
GO:0035613	RNA stem-loop binding	2/556	21/18639	0.0952380952380952	3.19270298047276	0.128652734640474	0.434299124576278
GO:0051010	microtubule plus-end binding	2/556	21/18639	0.0952380952380952	3.19270298047276	0.128652734640474	0.434299124576278
GO:0140312	cargo adaptor activity	2/556	21/18639	0.0952380952380952	3.19270298047276	0.128652734640474	0.434299124576278
GO:0120013	lipid transfer activity	4/556	65/18639	0.0615384615384615	2.06297731045932	0.128856917070042	0.434299124576278
GO:0019894	kinesin binding	3/556	42/18639	0.0714285714285714	2.39452723535457	0.129397341911425	0.434299124576278
GO:0042056	chemoattractant activity	3/556	42/18639	0.0714285714285714	2.39452723535457	0.129397341911425	0.434299124576278
GO:0030414	peptidase inhibitor activity	8/556	169/18639	0.0473372781065089	1.58690562343025	0.133587338006156	0.446650794249591
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	5/556	91/18639	0.0549450549450549	1.84194402719583	0.135833023460996	0.452432427953736
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	19/556	484/18639	0.0392561983471074	1.31600050538082	0.136814478396462	0.453975314679171
GO:1990782	protein tyrosine kinase binding	6/556	117/18639	0.0512820512820513	1.7191477587161	0.137408639299554	0.454226294439281
GO:0000295	adenine nucleotide transmembrane transporter activity	2/556	23/18639	0.0869565217391304	2.9150766343447	0.149216620154476	0.486772980159802
GO:0005158	insulin receptor binding	2/556	23/18639	0.0869565217391304	2.9150766343447	0.149216620154476	0.486772980159802
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/556	23/18639	0.0869565217391304	2.9150766343447	0.149216620154476	0.486772980159802
GO:0032182	ubiquitin-like protein binding	6/556	120/18639	0.05	1.6761690647482	0.149477090939483	0.486772980159802
GO:0004540	RNA nuclease activity	6/556	121/18639	0.0495867768595041	1.66231642784946	0.153602803942178	0.498355763901288
GO:0019209	kinase activator activity	7/556	148/18639	0.0472972972972973	1.58556533151857	0.154380404963877	0.4990303865253
GO:0030291	protein serine/threonine kinase inhibitor activity	3/556	46/18639	0.0652173913043478	2.18630747575852	0.157313400793676	0.505142346235022
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/556	24/18639	0.0833333333333333	2.79361510791367	0.159731084368837	0.505142346235022
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/556	24/18639	0.0833333333333333	2.79361510791367	0.159731084368837	0.505142346235022
GO:0019957	C-C chemokine binding	2/556	24/18639	0.0833333333333333	2.79361510791367	0.159731084368837	0.505142346235022
GO:0030552	cAMP binding	2/556	24/18639	0.0833333333333333	2.79361510791367	0.159731084368837	0.505142346235022
GO:0035035	histone acetyltransferase binding	2/556	24/18639	0.0833333333333333	2.79361510791367	0.159731084368837	0.505142346235022
GO:0043495	protein-membrane adaptor activity	3/556	47/18639	0.0638297872340425	2.13979029542324	0.164563218087712	0.514847782302983
GO:0140359	ABC-type transporter activity	3/556	47/18639	0.0638297872340425	2.13979029542324	0.164563218087712	0.514847782302983
GO:0140938	histone H3 methyltransferase activity	3/556	47/18639	0.0638297872340425	2.13979029542324	0.164563218087712	0.514847782302983
GO:0042379	chemokine receptor binding	4/556	72/18639	0.0555555555555556	1.86241007194245	0.167619901141566	0.522544602847017
GO:0008139	nuclear localization sequence binding	2/556	25/18639	0.08	2.68187050359712	0.170376173570424	0.523682554553304
GO:0017025	TBP-class protein binding	2/556	25/18639	0.08	2.68187050359712	0.170376173570424	0.523682554553304
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/556	25/18639	0.08	2.68187050359712	0.170376173570424	0.523682554553304
GO:0120020	cholesterol transfer activity	2/556	25/18639	0.08	2.68187050359712	0.170376173570424	0.523682554553304
GO:0004521	RNA endonuclease activity	4/556	73/18639	0.0547945205479452	1.83689760520351	0.173465801607807	0.530393019766891
GO:0004518	nuclease activity	9/556	209/18639	0.0430622009569378	1.44359058207979	0.173770315836869	0.530393019766891
GO:0001664	G protein-coupled receptor binding	12/556	297/18639	0.0404040404040404	1.35448005232178	0.178861855155803	0.53068250564264
GO:0003678	DNA helicase activity	4/556	74/18639	0.0540540540540541	1.81207466459265	0.17938098275531	0.53068250564264
GO:0048029	monosaccharide binding	4/556	74/18639	0.0540540540540541	1.81207466459265	0.17938098275531	0.53068250564264
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0008198	ferrous iron binding	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0019865	immunoglobulin binding	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0030507	spectrin binding	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0050750	low-density lipoprotein particle receptor binding	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0051139	metal cation:proton antiporter activity	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0052742	phosphatidylinositol kinase activity	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0070412	R-SMAD binding	2/556	26/18639	0.0769230769230769	2.57872163807416	0.181134782177111	0.53068250564264
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	6/556	128/18639	0.046875	1.57140849820144	0.183831764446879	0.536788752184888
GO:0017022	myosin binding	4/556	76/18639	0.0526315789473684	1.76438848920863	0.191408561947421	0.556900192195545
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/556	27/18639	0.0740740740740741	2.48321342925659	0.191990705528601	0.556900192195545
GO:0016798	hydrolase activity, acting on glycosyl bonds	6/556	130/18639	0.0461538461538462	1.54723298284449	0.192873561959755	0.557614654378696
GO:0005048	signal sequence binding	3/556	51/18639	0.0588235294117647	1.97196360558612	0.194476644713851	0.558562428751912
GO:0030544	Hsp70 protein binding	3/556	51/18639	0.0588235294117647	1.97196360558612	0.194476644713851	0.558562428751912
GO:0097718	disordered domain specific binding	2/556	28/18639	0.0714285714285714	2.39452723535457	0.202928601519592	0.580932859252166
GO:0019902	phosphatase binding	8/556	190/18639	0.0421052631578947	1.41151079136691	0.208139390047585	0.593909139028287
GO:0046332	SMAD binding	4/556	79/18639	0.0506329113924051	1.69738639468172	0.209902878857073	0.595161808788624
GO:0008013	beta-catenin binding	5/556	106/18639	0.0471698113207547	1.58129157051717	0.20993721337407	0.595161808788624
GO:0003785	actin monomer binding	2/556	29/18639	0.0689655172413793	2.31195733068717	0.213933953713658	0.597030124752041
GO:0106222	lncRNA binding	2/556	29/18639	0.0689655172413793	2.31195733068717	0.213933953713658	0.597030124752041
GO:0015297	antiporter activity	6/556	135/18639	0.0444444444444444	1.48992805755396	0.216182601105473	0.597030124752041
GO:0030246	carbohydrate binding	11/556	280/18639	0.0392857142857143	1.31698997944502	0.216478047206375	0.597030124752041
GO:0003925	G protein activity	3/556	54/18639	0.0555555555555556	1.86241007194245	0.217717932597369	0.597030124752041
GO:0015485	cholesterol binding	3/556	54/18639	0.0555555555555556	1.86241007194245	0.217717932597369	0.597030124752041
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/556	54/18639	0.0555555555555556	1.86241007194245	0.217717932597369	0.597030124752041
GO:0140463	chromatin-protein adaptor activity	3/556	54/18639	0.0555555555555556	1.86241007194245	0.217717932597369	0.597030124752041
GO:0030971	receptor tyrosine kinase binding	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0033192	calmodulin-dependent protein phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0140791	histone H2AXS140 phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:1990439	MAP kinase serine/threonine phosphatase activity	4/556	81/18639	0.0493827160493827	1.6554756195044	0.222503127093463	0.597030124752041
GO:0015103	inorganic anion transmembrane transporter activity	7/556	165/18639	0.0424242424242424	1.42220405493787	0.223400247879394	0.597030124752041
GO:0008187	poly-pyrimidine tract binding	2/556	30/18639	0.0666666666666667	2.23489208633094	0.224993035883891	0.597030124752041
GO:0051721	protein phosphatase 2A binding	2/556	30/18639	0.0666666666666667	2.23489208633094	0.224993035883891	0.597030124752041
GO:0070566	adenylyltransferase activity	2/556	30/18639	0.0666666666666667	2.23489208633094	0.224993035883891	0.597030124752041
GO:0008374	O-acyltransferase activity	3/556	55/18639	0.0545454545454545	1.8285480706344	0.225590149877769	0.597030124752041
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	4/556	82/18639	0.0487804878048781	1.63528689243727	0.228876438318053	0.602089369269113
GO:0033549	MAP kinase phosphatase activity	4/556	82/18639	0.0487804878048781	1.63528689243727	0.228876438318053	0.602089369269113
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/556	83/18639	0.0481927710843374	1.61558464072116	0.235294993003888	0.602524274678116
GO:0008135	translation factor activity, RNA binding	4/556	83/18639	0.0481927710843374	1.61558464072116	0.235294993003888	0.602524274678116
GO:1902936	phosphatidylinositol bisphosphate binding	5/556	111/18639	0.045045045045045	1.51006222049388	0.237106083857022	0.602524274678116
GO:0004713	protein tyrosine kinase activity	6/556	140/18639	0.0428571428571429	1.43671634121274	0.240390868602419	0.602524274678116
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3/556	57/18639	0.0526315789473684	1.76438848920863	0.241491487048821	0.602524274678116
GO:0004860	protein kinase inhibitor activity	4/556	84/18639	0.0476190476190476	1.59635149023638	0.241756145502267	0.602524274678116
GO:0017018	myosin phosphatase activity	4/556	84/18639	0.0476190476190476	1.59635149023638	0.241756145502267	0.602524274678116
GO:0180051	translation factor activity	4/556	84/18639	0.0476190476190476	1.59635149023638	0.241756145502267	0.602524274678116
GO:0022884	macromolecule transmembrane transporter activity	2/556	32/18639	0.0625	2.09521133093525	0.24722123310944	0.602524274678116
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/556	32/18639	0.0625	2.09521133093525	0.24722123310944	0.602524274678116
GO:0042910	xenobiotic transmembrane transporter activity	2/556	32/18639	0.0625	2.09521133093525	0.24722123310944	0.602524274678116
GO:0070717	poly-purine tract binding	2/556	32/18639	0.0625	2.09521133093525	0.24722123310944	0.602524274678116
GO:0000287	magnesium ion binding	9/556	230/18639	0.0391304347826087	1.31178448545511	0.249793381897978	0.602524274678116
GO:0015459	potassium channel regulator activity	3/556	59/18639	0.0508474576271186	1.70457870991343	0.257569061480072	0.602524274678116
GO:0030296	protein tyrosine kinase activator activity	2/556	33/18639	0.0606060606060606	2.03172007848267	0.258366546570634	0.602524274678116
GO:0035401	histone H3Y41 kinase activity	5/556	115/18639	0.0434782608695652	1.45753831717235	0.259499145547705	0.602524274678116
GO:0140801	histone H2AXY142 kinase activity	5/556	115/18639	0.0434782608695652	1.45753831717235	0.259499145547705	0.602524274678116
GO:0000182	rDNA binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0001094	TFIID-class transcription factor complex binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0003796	lysozyme activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0015203	polyamine transmembrane transporter activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0015643	toxic substance binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0030957	Tat protein binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0032395	MHC class II receptor activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0043208	glycosphingolipid binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0043422	protein kinase B binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0070097	delta-catenin binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0070513	death domain binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0099122	RNA polymerase II C-terminal domain binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0140940	histone H2A methyltransferase activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0141109	transporter activator activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:1905394	retromer complex binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:1990259	histone H2AQ104 methyltransferase activity	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:1990763	arrestin family protein binding	1/556	10/18639	0.1	3.3523381294964	0.261336754702445	0.602524274678116
GO:0008081	phosphoric diester hydrolase activity	4/556	87/18639	0.0459770114942529	1.54130488712478	0.261368977600096	0.602524274678116
GO:0003823	antigen binding	7/556	174/18639	0.0402298850574713	1.34864177623418	0.263669618900342	0.602664494082892
GO:0001098	basal transcription machinery binding	3/556	60/18639	0.05	1.6761690647482	0.265661946363394	0.602664494082892
GO:0001099	basal RNA polymerase II transcription machinery binding	3/556	60/18639	0.05	1.6761690647482	0.265661946363394	0.602664494082892
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3/556	60/18639	0.05	1.6761690647482	0.265661946363394	0.602664494082892
GO:0008376	acetylgalactosaminyltransferase activity	2/556	34/18639	0.0588235294117647	1.97196360558612	0.269517925080673	0.602664494082892
GO:0015026	coreceptor activity	3/556	61/18639	0.0491803278688525	1.64869088335889	0.2737847069277	0.602664494082892
GO:0016229	steroid dehydrogenase activity	2/556	35/18639	0.0571428571428571	1.91562178828366	0.280665107963215	0.602664494082892
GO:0043015	gamma-tubulin binding	2/556	35/18639	0.0571428571428571	1.91562178828366	0.280665107963215	0.602664494082892
GO:0019210	kinase inhibitor activity	4/556	90/18639	0.0444444444444444	1.48992805755396	0.281271682828044	0.602664494082892
GO:0001851	complement component C3b binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0002162	dystroglycan binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0003953	NAD+ nucleosidase activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0005114	type II transforming growth factor beta receptor binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0005225	volume-sensitive anion channel activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0008271	secondary active sulfate transmembrane transporter activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0008432	JUN kinase binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0015173	aromatic amino acid transmembrane transporter activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0015217	ADP transmembrane transporter activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0019215	intermediate filament binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0034056	estrogen response element binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0043522	leucine zipper domain binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0050998	nitric-oxide synthase binding	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0140537	transcription regulator activator activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:1990948	ubiquitin ligase inhibitor activity	1/556	11/18639	0.0909090909090909	3.047580117724	0.283382852957072	0.602664494082892
GO:0005507	copper ion binding	3/556	63/18639	0.0476190476190476	1.59635149023638	0.290101926678876	0.602664494082892
GO:1901682	sulfur compound transmembrane transporter activity	3/556	63/18639	0.0476190476190476	1.59635149023638	0.290101926678876	0.602664494082892
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/556	36/18639	0.0555555555555556	1.86241007194245	0.291798439166572	0.602664494082892
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/556	36/18639	0.0555555555555556	1.86241007194245	0.291798439166572	0.602664494082892
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/556	36/18639	0.0555555555555556	1.86241007194245	0.291798439166572	0.602664494082892
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/556	36/18639	0.0555555555555556	1.86241007194245	0.291798439166572	0.602664494082892
GO:0000510	H3-H4 histone complex chaperone activity	6/556	151/18639	0.0397350993377483	1.33205488589261	0.296129022631942	0.602664494082892
GO:0140584	chromatin extrusion motor activity	6/556	151/18639	0.0397350993377483	1.33205488589261	0.296129022631942	0.602664494082892
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	6/556	151/18639	0.0397350993377483	1.33205488589261	0.296129022631942	0.602664494082892
GO:0140849	ATP-dependent H2AZ histone chaperone activity	6/556	151/18639	0.0397350993377483	1.33205488589261	0.296129022631942	0.602664494082892
GO:0005539	glycosaminoglycan binding	9/556	242/18639	0.0371900826446281	1.24673732088709	0.297523195562647	0.602664494082892
GO:0015616	DNA translocase activity	6/556	152/18639	0.0394736842105263	1.32329136690647	0.301326824477822	0.602664494082892
GO:0140674	ATP-dependent histone chaperone activity	6/556	152/18639	0.0394736842105263	1.32329136690647	0.301326824477822	0.602664494082892
GO:0030551	cyclic nucleotide binding	2/556	37/18639	0.0540540540540541	1.81207466459265	0.30290884043214	0.602664494082892
GO:0005078	MAP-kinase scaffold activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0005095	GTPase inhibitor activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0008179	adenylate cyclase binding	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0008603	cAMP-dependent protein kinase regulator activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0016273	arginine N-methyltransferase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0016274	protein-arginine N-methyltransferase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0036009	protein-glutamine N-methyltransferase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0045295	gamma-catenin binding	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0070008	serine-type exopeptidase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0070679	inositol 1,4,5 trisphosphate binding	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0097677	STAT family protein binding	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/556	12/18639	0.0833333333333333	2.79361510791367	0.304772112875252	0.602664494082892
GO:0061775	cohesin loader activity	6/556	153/18639	0.0392156862745098	1.31464240372408	0.306541524603503	0.603441762904409
GO:1901681	sulfur compound binding	10/556	275/18639	0.0363636363636364	1.2190320470896	0.30654290467176	0.603441762904409
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	3/556	67/18639	0.0447761194029851	1.50104692365511	0.322903815258185	0.623980493029092
GO:0042054	histone methyltransferase activity	3/556	67/18639	0.0447761194029851	1.50104692365511	0.322903815258185	0.623980493029092
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/556	39/18639	0.0512820512820513	1.7191477587161	0.325027275459269	0.623980493029092
GO:0008253	5'-nucleotidase activity	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0035673	oligopeptide transmembrane transporter activity	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0039706	co-receptor binding	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0045159	myosin II binding	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0046974	histone H3K9 methyltransferase activity	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0070700	BMP receptor binding	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0071714	icosanoid transmembrane transporter activity	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0140333	glycerophospholipid flippase activity	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/556	13/18639	0.0769230769230769	2.57872163807416	0.325524069993488	0.623980493029092
GO:0140104	molecular carrier activity	9/556	249/18639	0.036144578313253	1.21168848054087	0.326353922381584	0.624205318790978
GO:1990841	promoter-specific chromatin binding	3/556	68/18639	0.0441176470588235	1.47897270418959	0.331115613437937	0.631933066169134
GO:0140658	ATP-dependent chromatin remodeler activity	6/556	158/18639	0.0379746835443038	1.27303979601129	0.332829605627882	0.633823335934837
GO:0008170	N-methyltransferase activity	4/556	98/18639	0.0408163265306122	1.36830127734547	0.335253403940398	0.634235514717673
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/556	40/18639	0.05	1.6761690647482	0.336019814765505	0.634235514717673
GO:0050997	quaternary ammonium group binding	2/556	40/18639	0.05	1.6761690647482	0.336019814765505	0.634235514717673
GO:0002039	p53 binding	3/556	69/18639	0.0434782608695652	1.45753831717235	0.339324316330022	0.634235514717673
GO:0016279	protein-lysine N-methyltransferase activity	3/556	69/18639	0.0434782608695652	1.45753831717235	0.339324316330022	0.634235514717673
GO:0003689	DNA clamp loader activity	6/556	160/18639	0.0375	1.25712679856115	0.343424482439217	0.634235514717673
GO:0004705	JUN kinase activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0008191	metalloendopeptidase inhibitor activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0015386	potassium:proton antiporter activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0019763	immunoglobulin receptor activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0019992	diacylglycerol binding	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0032454	histone H3K9 demethylase activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0034236	protein kinase A catalytic subunit binding	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0046030	inositol trisphosphate phosphatase activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0061665	SUMO ligase activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0061783	peptidoglycan muralytic activity	1/556	14/18639	0.0714285714285714	2.39452723535457	0.345657679844428	0.634235514717673
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	5/556	130/18639	0.0384615384615385	1.28936081903708	0.346837098631679	0.634235514717673
GO:0140828	metal cation:monoatomic cation antiporter activity	2/556	41/18639	0.0487804878048781	1.63528689243727	0.346958388622166	0.634235514717673
GO:0016278	lysine N-methyltransferase activity	3/556	70/18639	0.0428571428571429	1.43671634121274	0.347526309434341	0.634235514717673
GO:0015291	secondary active transmembrane transporter activity	10/556	287/18639	0.0348432055749129	1.16806206602662	0.353618768134803	0.635999223834171
GO:0016859	cis-trans isomerase activity	2/556	42/18639	0.0476190476190476	1.59635149023638	0.357836440957703	0.635999223834171
GO:0008236	serine-type peptidase activity	7/556	194/18639	0.0360824742268041	1.20960654157087	0.358788403483167	0.635999223834171
GO:0000774	adenyl-nucleotide exchange factor activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0004559	alpha-mannosidase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0004953	icosanoid receptor activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0005523	tropomyosin binding	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0008252	nucleotidase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0015116	sulfate transmembrane transporter activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0016846	carbon-sulfur lyase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0031005	filamin binding	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0033130	acetylcholine receptor binding	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0047372	monoacylglycerol lipase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0050700	CARD domain binding	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0050780	dopamine receptor binding	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0061578	K63-linked deubiquitinase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0141050	histone H3K deacetylase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0141051	histone H4K deacetylase activity	1/556	15/18639	0.0666666666666667	2.23489208633094	0.36519133514679	0.635999223834171
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/556	43/18639	0.0465116279069767	1.55922703697507	0.368647853404483	0.638010884909589
GO:0008375	acetylglucosaminyltransferase activity	2/556	43/18639	0.0465116279069767	1.55922703697507	0.368647853404483	0.638010884909589
GO:0048156	tau protein binding	2/556	43/18639	0.0465116279069767	1.55922703697507	0.368647853404483	0.638010884909589
GO:0004722	protein serine/threonine phosphatase activity	4/556	103/18639	0.0388349514563107	1.30187888524132	0.369259724485344	0.638010884909589
GO:0043539	protein serine/threonine kinase activator activity	3/556	73/18639	0.0410958904109589	1.37767320390263	0.372057579518363	0.641579605626154
GO:0017171	serine hydrolase activity	7/556	198/18639	0.0353535353535354	1.18517004578156	0.378303544453569	0.642193063088444
GO:0001046	core promoter sequence-specific DNA binding	2/556	44/18639	0.0454545454545455	1.523790058862	0.379386925100249	0.642193063088444
GO:0019205	nucleobase-containing compound kinase activity	2/556	44/18639	0.0454545454545455	1.523790058862	0.379386925100249	0.642193063088444
GO:0003730	mRNA 3'-UTR binding	9/556	262/18639	0.0343511450381679	1.15156653303312	0.381088515885041	0.642193063088444
GO:0019838	growth factor binding	5/556	136/18639	0.0367647058823529	1.23247725349132	0.382445665037058	0.642193063088444
GO:0003688	DNA replication origin binding	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0004707	MAP kinase activity	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0005159	insulin-like growth factor receptor binding	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0005521	lamin binding	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0019841	retinol binding	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0030275	LRR domain binding	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0140327	flippase activity	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0140328	floppase activity	1/556	16/18639	0.0625	2.09521133093525	0.384142882486695	0.642193063088444
GO:0005125	cytokine activity	8/556	234/18639	0.0341880341880342	1.14609850581074	0.398230462593528	0.65058295817487
GO:0016757	glycosyltransferase activity	9/556	267/18639	0.0337078651685393	1.13000161668418	0.402354708924347	0.65058295817487
GO:0004550	nucleoside diphosphate kinase activity	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0005092	GDP-dissociation inhibitor activity	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0008429	phosphatidylethanolamine binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0015278	intracellularly gated calcium channel activity	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0016018	cyclosporin A binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0016805	dipeptidase activity	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0032183	SUMO binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0036041	long-chain fatty acid binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0046965	nuclear retinoid X receptor binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0051787	misfolded protein binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0070403	NAD+ binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0070492	oligosaccharide binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:1990226	histone methyltransferase binding	1/556	17/18639	0.0588235294117647	1.97196360558612	0.402529638505456	0.65058295817487
GO:0008201	heparin binding	6/556	172/18639	0.0348837209302326	1.1694202777313	0.40738695377262	0.657220941997818
GO:0001784	phosphotyrosine residue binding	2/556	47/18639	0.0425531914893617	1.42652686361549	0.411118947965533	0.660807703518912
GO:0005504	fatty acid binding	2/556	47/18639	0.0425531914893617	1.42652686361549	0.411118947965533	0.660807703518912
GO:0004706	JUN kinase kinase kinase activity	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0008409	5'-3' exonuclease activity	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0015172	acidic amino acid transmembrane transporter activity	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0017075	syntaxin-1 binding	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0034185	apolipoprotein binding	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0070064	proline-rich region binding	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0098641	cadherin binding involved in cell-cell adhesion	1/556	18/18639	0.0555555555555556	1.86241007194245	0.420368405608397	0.664908430527356
GO:0033293	monocarboxylic acid binding	3/556	79/18639	0.0379746835443038	1.27303979601129	0.420501450356342	0.664908430527356
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/556	48/18639	0.0416666666666667	1.39680755395683	0.421519335826456	0.665317005736893
GO:0048306	calcium-dependent protein binding	3/556	80/18639	0.0375	1.25712679856115	0.428462115262691	0.667950743545189
GO:0004252	serine-type endopeptidase activity	6/556	176/18639	0.0340909090909091	1.1428425441465	0.428665799877164	0.667950743545189
GO:0019903	protein phosphatase binding	5/556	144/18639	0.0347222222222222	1.16400629496403	0.42975338075886	0.667950743545189
GO:0001222	transcription corepressor binding	2/556	49/18639	0.0408163265306122	1.36830127734547	0.431824489430496	0.667950743545189
GO:0016763	pentosyltransferase activity	2/556	49/18639	0.0408163265306122	1.36830127734547	0.431824489430496	0.667950743545189
GO:0043021	ribonucleoprotein complex binding	6/556	177/18639	0.0338983050847458	1.13638580660895	0.433968884889345	0.667950743545189
GO:0015101	organic cation transmembrane transporter activity	3/556	81/18639	0.037037037037037	1.2416067146283	0.436383614807661	0.667950743545189
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0005229	intracellularly calcium-gated chloride channel activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0008574	plus-end-directed microtubule motor activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0016918	retinal binding	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0022821	solute:potassium antiporter activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0030506	ankyrin binding	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0050145	nucleoside monophosphate kinase activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0097001	ceramide binding	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0140036	ubiquitin-modified protein reader activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0141147	intracellularly calcium-gated channel activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:1990380	K48-linked deubiquitinase activity	1/556	19/18639	0.0526315789473684	1.76438848920863	0.437675487208834	0.667950743545189
GO:0005319	lipid transporter activity	6/556	178/18639	0.0337078651685393	1.13000161668418	0.439263553006085	0.669208473797096
GO:0032813	tumor necrosis factor receptor superfamily binding	2/556	50/18639	0.04	1.34093525179856	0.442030832188387	0.671090136909926
GO:0048020	CCR chemokine receptor binding	2/556	50/18639	0.04	1.34093525179856	0.442030832188387	0.671090136909926
GO:0015085	calcium ion transmembrane transporter activity	5/556	147/18639	0.0340136054421769	1.14025106445456	0.447325854790954	0.677062638449602
GO:0003743	translation initiation factor activity	2/556	51/18639	0.0392156862745098	1.31464240372408	0.452135084738369	0.677062638449602
GO:0005021	vascular endothelial growth factor receptor activity	2/556	51/18639	0.0392156862745098	1.31464240372408	0.452135084738369	0.677062638449602
GO:0016597	amino acid binding	2/556	51/18639	0.0392156862745098	1.31464240372408	0.452135084738369	0.677062638449602
GO:0016004	phospholipase activator activity	1/556	20/18639	0.05	1.6761690647482	0.454466702520966	0.677062638449602
GO:0016505	peptidase activator activity involved in apoptotic process	1/556	20/18639	0.05	1.6761690647482	0.454466702520966	0.677062638449602
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/556	20/18639	0.05	1.6761690647482	0.454466702520966	0.677062638449602
GO:0042288	MHC class I protein binding	1/556	20/18639	0.05	1.6761690647482	0.454466702520966	0.677062638449602
GO:0043024	ribosomal small subunit binding	1/556	20/18639	0.05	1.6761690647482	0.454466702520966	0.677062638449602
GO:0052745	inositol phosphate phosphatase activity	1/556	20/18639	0.05	1.6761690647482	0.454466702520966	0.677062638449602
GO:0140939	histone H4 methyltransferase activity	1/556	20/18639	0.05	1.6761690647482	0.454466702520966	0.677062638449602
GO:0019208	phosphatase regulator activity	4/556	117/18639	0.0341880341880342	1.14609850581074	0.463148202817844	0.688824831355571
GO:0005123	death receptor binding	1/556	21/18639	0.0476190476190476	1.59635149023638	0.47075740091499	0.692620480653431
GO:0008373	sialyltransferase activity	1/556	21/18639	0.0476190476190476	1.59635149023638	0.47075740091499	0.692620480653431
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/556	21/18639	0.0476190476190476	1.59635149023638	0.47075740091499	0.692620480653431
GO:0015125	bile acid transmembrane transporter activity	1/556	21/18639	0.0476190476190476	1.59635149023638	0.47075740091499	0.692620480653431
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/556	21/18639	0.0476190476190476	1.59635149023638	0.47075740091499	0.692620480653431
GO:0070182	DNA polymerase binding	1/556	21/18639	0.0476190476190476	1.59635149023638	0.47075740091499	0.692620480653431
GO:0038064	collagen receptor activity	2/556	53/18639	0.0377358490566038	1.26503325641374	0.472025601541208	0.692620480653431
GO:0051018	protein kinase A binding	2/556	53/18639	0.0377358490566038	1.26503325641374	0.472025601541208	0.692620480653431
GO:0016209	antioxidant activity	3/556	86/18639	0.0348837209302326	1.1694202777313	0.475326066347751	0.696297047024465
GO:0015631	tubulin binding	12/556	385/18639	0.0311688311688312	1.04488461179109	0.479806634454765	0.701687164912144
GO:0004407	histone deacetylase activity	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0008093	cytoskeletal anchor activity	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0033558	protein lysine deacetylase activity	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0050321	tau-protein kinase activity	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0070034	telomerase RNA binding	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0140035	ubiquitin-like protein reader activity	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0140517	protein-RNA adaptor activity	1/556	22/18639	0.0454545454545455	1.523790058862	0.486562475847382	0.702189009624887
GO:0003697	single-stranded DNA binding	4/556	121/18639	0.0330578512396694	1.10821095189964	0.489147463579403	0.704758516604535
GO:0004386	helicase activity	5/556	155/18639	0.032258064516129	1.08139939661174	0.493427518118526	0.709131012032091
GO:0003713	transcription coactivator activity	8/556	256/18639	0.03125	1.04760566546763	0.497267236609545	0.709131012032091
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0004602	glutathione peroxidase activity	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0005212	structural constituent of eye lens	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0016493	C-C chemokine receptor activity	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0017134	fibroblast growth factor binding	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0031681	G-protein beta-subunit binding	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0043274	phospholipase binding	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0099186	structural constituent of postsynapse	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0140103	catalytic activity, acting on a glycoprotein	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/556	23/18639	0.0434782608695652	1.45753831717235	0.501896378378877	0.709131012032091
GO:0016755	aminoacyltransferase activity	15/556	496/18639	0.030241935483871	1.01381193432351	0.515618429026061	0.72084914352883
GO:0004806	triacylglycerol lipase activity	1/556	24/18639	0.0416666666666667	1.39680755395683	0.516773130292357	0.72084914352883
GO:0005540	hyaluronic acid binding	1/556	24/18639	0.0416666666666667	1.39680755395683	0.516773130292357	0.72084914352883
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/556	24/18639	0.0416666666666667	1.39680755395683	0.516773130292357	0.72084914352883
GO:0050431	transforming growth factor beta binding	1/556	24/18639	0.0416666666666667	1.39680755395683	0.516773130292357	0.72084914352883
GO:0060229	lipase activator activity	1/556	24/18639	0.0416666666666667	1.39680755395683	0.516773130292357	0.72084914352883
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/556	24/18639	0.0416666666666667	1.39680755395683	0.516773130292357	0.72084914352883
GO:0070840	dynein complex binding	1/556	24/18639	0.0416666666666667	1.39680755395683	0.516773130292357	0.72084914352883
GO:0051213	dioxygenase activity	3/556	93/18639	0.032258064516129	1.08139939661174	0.527640361204196	0.72482359977641
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/556	59/18639	0.0338983050847458	1.13638580660895	0.528987475075971	0.72482359977641
GO:0036002	pre-mRNA binding	2/556	59/18639	0.0338983050847458	1.13638580660895	0.528987475075971	0.72482359977641
GO:0045309	protein phosphorylated amino acid binding	2/556	59/18639	0.0338983050847458	1.13638580660895	0.528987475075971	0.72482359977641
GO:0070063	RNA polymerase binding	2/556	59/18639	0.0338983050847458	1.13638580660895	0.528987475075971	0.72482359977641
GO:0000030	mannosyltransferase activity	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0001848	complement binding	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0004709	MAP kinase kinase kinase activity	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0017056	structural constituent of nuclear pore	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0019707	protein-cysteine S-acyltransferase activity	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0042974	nuclear retinoic acid receptor binding	1/556	25/18639	0.04	1.34093525179856	0.531206336822438	0.72482359977641
GO:0008083	growth factor activity	5/556	162/18639	0.0308641975308642	1.03467226219025	0.532560262783046	0.725457812945035
GO:0031490	chromatin DNA binding	4/556	128/18639	0.03125	1.04760566546763	0.533327433260962	0.725457812945035
GO:0042562	hormone binding	3/556	94/18639	0.0319148936170213	1.06989514771162	0.534876558998588	0.725840818132565
GO:0016758	hexosyltransferase activity	6/556	197/18639	0.0304568527918782	1.02101668918672	0.537209514522123	0.725840818132565
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/556	60/18639	0.0333333333333333	1.11744604316547	0.538067665721232	0.725840818132565
GO:0004867	serine-type endopeptidase inhibitor activity	3/556	95/18639	0.0315789473684211	1.05863309352518	0.542049595822866	0.725840818132565
GO:0008276	protein methyltransferase activity	3/556	95/18639	0.0315789473684211	1.05863309352518	0.542049595822866	0.725840818132565
GO:0001637	G protein-coupled chemoattractant receptor activity	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0004529	DNA exonuclease activity	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0004950	chemokine receptor activity	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0005160	transforming growth factor beta receptor binding	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0008143	poly(A) binding	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0034237	protein kinase A regulatory subunit binding	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0043548	phosphatidylinositol 3-kinase binding	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0050681	nuclear androgen receptor binding	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0070006	metalloaminopeptidase activity	1/556	26/18639	0.0384615384615385	1.28936081903708	0.545209199008251	0.725840818132565
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	2/556	61/18639	0.0327868852459016	1.09912725557259	0.547026410087115	0.726053235206534
GO:0016836	hydro-lyase activity	2/556	61/18639	0.0327868852459016	1.09912725557259	0.547026410087115	0.726053235206534
GO:0004175	endopeptidase activity	12/556	405/18639	0.0296296296296296	0.993285371702638	0.5508454844414	0.728428578119283
GO:0005262	calcium channel activity	4/556	131/18639	0.0305343511450382	1.02361469602944	0.551673971786915	0.728428578119283
GO:0008514	organic anion transmembrane transporter activity	8/556	269/18639	0.0297397769516729	0.996977882378112	0.553603748282032	0.728428578119283
GO:0061659	ubiquitin-like protein ligase activity	11/556	372/18639	0.0295698924731183	0.991282780227431	0.55486947220018	0.728428578119283
GO:0015179	L-amino acid transmembrane transporter activity	2/556	62/18639	0.032258064516129	1.08139939661174	0.555862862625503	0.728428578119283
GO:0004364	glutathione transferase activity	1/556	27/18639	0.037037037037037	1.2416067146283	0.558794525680546	0.728428578119283
GO:0005104	fibroblast growth factor receptor binding	1/556	27/18639	0.037037037037037	1.2416067146283	0.558794525680546	0.728428578119283
GO:0008266	poly(U) RNA binding	1/556	27/18639	0.037037037037037	1.2416067146283	0.558794525680546	0.728428578119283
GO:0008320	protein transmembrane transporter activity	1/556	27/18639	0.037037037037037	1.2416067146283	0.558794525680546	0.728428578119283
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/556	27/18639	0.037037037037037	1.2416067146283	0.558794525680546	0.728428578119283
GO:0035255	ionotropic glutamate receptor binding	1/556	27/18639	0.037037037037037	1.2416067146283	0.558794525680546	0.728428578119283
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/556	27/18639	0.037037037037037	1.2416067146283	0.558794525680546	0.728428578119283
GO:0016874	ligase activity	5/556	167/18639	0.029940119760479	1.00369405074743	0.559659485742971	0.728472079510911
GO:0005201	extracellular matrix structural constituent	5/556	168/18639	0.0297619047619048	0.997719681397739	0.564985061574466	0.733601576430847
GO:0005261	monoatomic cation channel activity	10/556	341/18639	0.0293255131964809	0.98309036055613	0.566897867258916	0.733601576430847
GO:0019787	ubiquitin-like protein transferase activity	14/556	479/18639	0.0292275574112735	0.979806551418573	0.569546060809381	0.733601576430847
GO:0019789	SUMO transferase activity	1/556	28/18639	0.0357142857142857	1.19726361767729	0.571974745093914	0.733601576430847
GO:0046625	sphingolipid binding	1/556	28/18639	0.0357142857142857	1.19726361767729	0.571974745093914	0.733601576430847
GO:0046966	nuclear thyroid hormone receptor binding	1/556	28/18639	0.0357142857142857	1.19726361767729	0.571974745093914	0.733601576430847
GO:0050698	proteoglycan sulfotransferase activity	1/556	28/18639	0.0357142857142857	1.19726361767729	0.571974745093914	0.733601576430847
GO:0051537	2 iron, 2 sulfur cluster binding	1/556	28/18639	0.0357142857142857	1.19726361767729	0.571974745093914	0.733601576430847
GO:0051959	dynein light intermediate chain binding	1/556	28/18639	0.0357142857142857	1.19726361767729	0.571974745093914	0.733601576430847
GO:0141052	histone H3 demethylase activity	1/556	28/18639	0.0357142857142857	1.19726361767729	0.571974745093914	0.733601576430847
GO:0004536	DNA nuclease activity	2/556	64/18639	0.03125	1.04760566546763	0.573166292111109	0.734055075861596
GO:0016779	nucleotidyltransferase activity	4/556	136/18639	0.0294117647058824	0.98598180279306	0.581381367710113	0.74131901389873
GO:0019843	rRNA binding	2/556	65/18639	0.0307692307692308	1.03148865522966	0.581632334466822	0.74131901389873
GO:0038024	cargo receptor activity	2/556	65/18639	0.0307692307692308	1.03148865522966	0.581632334466822	0.74131901389873
GO:0008017	microtubule binding	8/556	276/18639	0.0289855072463768	0.971692211448233	0.582833378024327	0.74131901389873
GO:0004842	ubiquitin-protein transferase activity	13/556	449/18639	0.0289532293986637	0.970610148851965	0.5834863126604	0.74131901389873
GO:0016417	S-acyltransferase activity	1/556	29/18639	0.0344827586206897	1.15597866534359	0.584761916214637	0.74131901389873
GO:0099604	ligand-gated calcium channel activity	1/556	29/18639	0.0344827586206897	1.15597866534359	0.584761916214637	0.74131901389873
GO:0008235	metalloexopeptidase activity	2/556	66/18639	0.0303030303030303	1.01586003924133	0.589974199617072	0.746126382342757
GO:0008238	exopeptidase activity	3/556	102/18639	0.0294117647058824	0.98598180279306	0.590409990870519	0.746126382342757
GO:0140030	modification-dependent protein binding	5/556	173/18639	0.0289017341040462	0.968883852455608	0.591109257244147	0.746126382342757
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/556	30/18639	0.0333333333333333	1.11744604316547	0.597167739674318	0.746246704642943
GO:0031210	phosphatidylcholine binding	1/556	30/18639	0.0333333333333333	1.11744604316547	0.597167739674318	0.746246704642943
GO:0031624	ubiquitin conjugating enzyme binding	1/556	30/18639	0.0333333333333333	1.11744604316547	0.597167739674318	0.746246704642943
GO:0032452	histone demethylase activity	1/556	30/18639	0.0333333333333333	1.11744604316547	0.597167739674318	0.746246704642943
GO:0033612	receptor serine/threonine kinase binding	1/556	30/18639	0.0333333333333333	1.11744604316547	0.597167739674318	0.746246704642943
GO:0048019	receptor antagonist activity	1/556	30/18639	0.0333333333333333	1.11744604316547	0.597167739674318	0.746246704642943
GO:0098918	structural constituent of synapse	1/556	30/18639	0.0333333333333333	1.11744604316547	0.597167739674318	0.746246704642943
GO:0008094	ATP-dependent activity, acting on DNA	6/556	210/18639	0.0285714285714286	0.957810894141829	0.599804800746805	0.748474366743876
GO:0003777	microtubule motor activity	2/556	68/18639	0.0294117647058824	0.98598180279306	0.606284966161617	0.752697215680801
GO:0030145	manganese ion binding	2/556	68/18639	0.0294117647058824	0.98598180279306	0.606284966161617	0.752697215680801
GO:0005164	tumor necrosis factor receptor binding	1/556	31/18639	0.032258064516129	1.08139939661174	0.609203568399187	0.752697215680801
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/556	31/18639	0.032258064516129	1.08139939661174	0.609203568399187	0.752697215680801
GO:0005452	solute:inorganic anion antiporter activity	1/556	31/18639	0.032258064516129	1.08139939661174	0.609203568399187	0.752697215680801
GO:0072349	modified amino acid transmembrane transporter activity	1/556	31/18639	0.032258064516129	1.08139939661174	0.609203568399187	0.752697215680801
GO:0140457	protein demethylase activity	1/556	31/18639	0.032258064516129	1.08139939661174	0.609203568399187	0.752697215680801
GO:0061630	ubiquitin protein ligase activity	10/556	353/18639	0.028328611898017	0.949670858214278	0.610817635451503	0.753628519233122
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/556	70/18639	0.0285714285714286	0.957810894141829	0.622098871117253	0.766467807452481
GO:0016853	isomerase activity	5/556	180/18639	0.0277777777777778	0.931205035971223	0.626183824180647	0.770417176941357
GO:0008194	UDP-glycosyltransferase activity	4/556	145/18639	0.0275862068965517	0.92478293227487	0.631884204052932	0.776340200210895
GO:0015020	glucuronosyltransferase activity	1/556	34/18639	0.0294117647058824	0.98598180279306	0.643199614323379	0.786931371714078
GO:0030332	cyclin binding	1/556	34/18639	0.0294117647058824	0.98598180279306	0.643199614323379	0.786931371714078
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/556	34/18639	0.0294117647058824	0.98598180279306	0.643199614323379	0.786931371714078
GO:0043022	ribosome binding	3/556	112/18639	0.0267857142857143	0.897947713257965	0.653535156371073	0.794429205375664
GO:0005154	epidermal growth factor receptor binding	1/556	35/18639	0.0285714285714286	0.957810894141829	0.653862393922207	0.794429205375664
GO:0010485	histone H4 acetyltransferase activity	1/556	35/18639	0.0285714285714286	0.957810894141829	0.653862393922207	0.794429205375664
GO:0061631	ubiquitin conjugating enzyme activity	1/556	35/18639	0.0285714285714286	0.957810894141829	0.653862393922207	0.794429205375664
GO:0140566	histone reader activity	1/556	35/18639	0.0285714285714286	0.957810894141829	0.653862393922207	0.794429205375664
GO:0031406	carboxylic acid binding	5/556	187/18639	0.0267379679144385	0.896347093448236	0.659389553426806	0.799238187677426
GO:0000993	RNA polymerase II complex binding	1/556	36/18639	0.0277777777777778	0.931205035971223	0.664207078343797	0.799238187677426
GO:0004033	aldo-keto reductase (NADPH) activity	1/556	36/18639	0.0277777777777778	0.931205035971223	0.664207078343797	0.799238187677426
GO:0004190	aspartic-type endopeptidase activity	1/556	36/18639	0.0277777777777778	0.931205035971223	0.664207078343797	0.799238187677426
GO:0016409	palmitoyltransferase activity	1/556	36/18639	0.0277777777777778	0.931205035971223	0.664207078343797	0.799238187677426
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/556	36/18639	0.0277777777777778	0.931205035971223	0.664207078343797	0.799238187677426
GO:0055106	ubiquitin-protein transferase regulator activity	1/556	36/18639	0.0277777777777778	0.931205035971223	0.664207078343797	0.799238187677426
GO:0051536	iron-sulfur cluster binding	2/556	76/18639	0.0263157894736842	0.882194244604317	0.66658626319965	0.799903515839579
GO:0098631	cell adhesion mediator activity	2/556	76/18639	0.0263157894736842	0.882194244604317	0.66658626319965	0.799903515839579
GO:0043177	organic acid binding	5/556	189/18639	0.0264550264550265	0.886861939020212	0.668520033027396	0.801126605926127
GO:0003724	RNA helicase activity	2/556	77/18639	0.025974025974026	0.870737176492572	0.67357596643118	0.802495911800294
GO:0051540	metal cluster binding	2/556	77/18639	0.025974025974026	0.870737176492572	0.67357596643118	0.802495911800294
GO:0019213	deacetylase activity	1/556	37/18639	0.027027027027027	0.906037332296325	0.67424314050801	0.802495911800294
GO:0042805	actinin binding	1/556	37/18639	0.027027027027027	0.906037332296325	0.67424314050801	0.802495911800294
GO:0070001	aspartic-type peptidase activity	1/556	37/18639	0.027027027027027	0.906037332296325	0.67424314050801	0.802495911800294
GO:0005506	iron ion binding	4/556	154/18639	0.025974025974026	0.870737176492572	0.678301698763558	0.806231055789521
GO:0019199	transmembrane receptor protein kinase activity	2/556	78/18639	0.0256410256410256	0.859573879358052	0.680446280383348	0.807501725107972
GO:0005109	frizzled binding	1/556	38/18639	0.0263157894736842	0.882194244604317	0.683979771723876	0.807501725107972
GO:0005501	retinoid binding	1/556	38/18639	0.0263157894736842	0.882194244604317	0.683979771723876	0.807501725107972
GO:0019840	isoprenoid binding	1/556	38/18639	0.0263157894736842	0.882194244604317	0.683979771723876	0.807501725107972
GO:0042887	amide transmembrane transporter activity	1/556	38/18639	0.0263157894736842	0.882194244604317	0.683979771723876	0.807501725107972
GO:0008186	ATP-dependent activity, acting on RNA	2/556	79/18639	0.0253164556962025	0.848693197340861	0.687198094150284	0.809120336660818
GO:0016835	carbon-oxygen lyase activity	2/556	79/18639	0.0253164556962025	0.848693197340861	0.687198094150284	0.809120336660818
GO:0016776	phosphotransferase activity, phosphate group as acceptor	1/556	39/18639	0.0256410256410256	0.859573879358052	0.693425890046629	0.814264181877811
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/556	39/18639	0.0256410256410256	0.859573879358052	0.693425890046629	0.814264181877811
GO:0004177	aminopeptidase activity	1/556	40/18639	0.025	0.838084532374101	0.702590148387171	0.820625293316215
GO:0030331	nuclear estrogen receptor binding	1/556	40/18639	0.025	0.838084532374101	0.702590148387171	0.820625293316215
GO:0032451	demethylase activity	1/556	40/18639	0.025	0.838084532374101	0.702590148387171	0.820625293316215
GO:0071949	FAD binding	1/556	40/18639	0.025	0.838084532374101	0.702590148387171	0.820625293316215
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/556	122/18639	0.0245901639344262	0.824345441679443	0.709385969148928	0.826359187466038
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/556	122/18639	0.0245901639344262	0.824345441679443	0.709385969148928	0.826359187466038
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/556	41/18639	0.024390243902439	0.817643446218635	0.711480942381296	0.826601200962885
GO:0140318	protein transporter activity	1/556	41/18639	0.024390243902439	0.817643446218635	0.711480942381296	0.826601200962885
GO:0004402	histone acetyltransferase activity	1/556	42/18639	0.0238095238095238	0.798175745118191	0.720106418025773	0.831110964677968
GO:0004520	DNA endonuclease activity	1/556	42/18639	0.0238095238095238	0.798175745118191	0.720106418025773	0.831110964677968
GO:0008307	structural constituent of muscle	1/556	42/18639	0.0238095238095238	0.798175745118191	0.720106418025773	0.831110964677968
GO:0043175	RNA polymerase core enzyme binding	1/556	42/18639	0.0238095238095238	0.798175745118191	0.720106418025773	0.831110964677968
GO:0048487	beta-tubulin binding	1/556	42/18639	0.0238095238095238	0.798175745118191	0.720106418025773	0.831110964677968
GO:0140098	catalytic activity, acting on RNA	10/556	387/18639	0.0258397932816537	0.866237242763928	0.721867957022279	0.832047803094101
GO:0005245	voltage-gated calcium channel activity	1/556	43/18639	0.0232558139534884	0.779613518487536	0.728474479088185	0.837458849975394
GO:0008200	ion channel inhibitor activity	1/556	43/18639	0.0232558139534884	0.779613518487536	0.728474479088185	0.837458849975394
GO:0050660	flavin adenine dinucleotide binding	2/556	86/18639	0.0232558139534884	0.779613518487536	0.731227682356987	0.839067178181089
GO:0008168	methyltransferase activity	5/556	204/18639	0.0245098039215686	0.82165150232755	0.731789182797205	0.839067178181089
GO:0016248	channel inhibitor activity	1/556	44/18639	0.0227272727272727	0.761895029431001	0.736592794297207	0.840176155995252
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/556	44/18639	0.0227272727272727	0.761895029431001	0.736592794297207	0.840176155995252
GO:0030547	signaling receptor inhibitor activity	1/556	44/18639	0.0227272727272727	0.761895029431001	0.736592794297207	0.840176155995252
GO:0043014	alpha-tubulin binding	1/556	44/18639	0.0227272727272727	0.761895029431001	0.736592794297207	0.840176155995252
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	4/556	167/18639	0.0239520958083832	0.802955240597941	0.73787332045198	0.840542300020721
GO:0051539	4 iron, 4 sulfur cluster binding	1/556	45/18639	0.0222222222222222	0.744964028776978	0.744468804319834	0.844759938580537
GO:0140303	intramembrane lipid transporter activity	1/556	45/18639	0.0222222222222222	0.744964028776978	0.744468804319834	0.844759938580537
GO:0141110	transporter inhibitor activity	1/556	45/18639	0.0222222222222222	0.744964028776978	0.744468804319834	0.844759938580537
GO:0003727	single-stranded RNA binding	2/556	89/18639	0.0224719101123595	0.753334411122787	0.748427578316619	0.848153374651175
GO:0004180	carboxypeptidase activity	1/556	46/18639	0.0217391304347826	0.728769158586174	0.752109728531847	0.850126609282449
GO:0030276	clathrin binding	1/556	46/18639	0.0217391304347826	0.728769158586174	0.752109728531847	0.850126609282449
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3/556	132/18639	0.0227272727272727	0.761895029431001	0.758059063089941	0.854670004586835
GO:0061733	protein-lysine-acetyltransferase activity	1/556	47/18639	0.0212765957446809	0.713263431807745	0.759522571587637	0.854670004586835
GO:0099095	ligand-gated monoatomic anion channel activity	1/556	47/18639	0.0212765957446809	0.713263431807745	0.759522571587637	0.854670004586835
GO:0052689	carboxylic ester hydrolase activity	2/556	92/18639	0.0217391304347826	0.728769158586174	0.76467366175208	0.854670004586835
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/556	48/18639	0.0208333333333333	0.698403776978417	0.766714129795321	0.854670004586835
GO:0051219	phosphoprotein binding	2/556	93/18639	0.021505376344086	0.720932931074495	0.769883184841045	0.854670004586835
GO:0016741	transferase activity, transferring one-carbon groups	5/556	215/18639	0.0232558139534884	0.779613518487536	0.772311149180272	0.854670004586835
GO:0005004	GPI-linked ephrin receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0005008	hepatocyte growth factor receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0005009	insulin receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0005011	macrophage colony-stimulating factor receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0005020	stem cell factor receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0008288	boss receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0035254	glutamate receptor binding	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0036332	placental growth factor receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0038062	protein tyrosine kinase collagen receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0060175	brain-derived neurotrophic factor receptor activity	1/556	49/18639	0.0204081632653061	0.684150638672735	0.773690997302922	0.854670004586835
GO:0005006	epidermal growth factor receptor activity	1/556	50/18639	0.02	0.670467625899281	0.780459572101178	0.857820056663277
GO:0005007	fibroblast growth factor receptor activity	1/556	50/18639	0.02	0.670467625899281	0.780459572101178	0.857820056663277
GO:0005017	platelet-derived growth factor receptor activity	1/556	50/18639	0.02	0.670467625899281	0.780459572101178	0.857820056663277
GO:0005019	platelet-derived growth factor beta-receptor activity	1/556	50/18639	0.02	0.670467625899281	0.780459572101178	0.857820056663277
GO:0005216	monoatomic ion channel activity	11/556	448/18639	0.0245535714285714	0.823118737153135	0.785455889281887	0.861110444638151
GO:0005010	insulin-like growth factor receptor activity	1/556	51/18639	0.0196078431372549	0.65732120186204	0.787026061848434	0.861110444638151
GO:0005030	neurotrophin receptor activity	1/556	51/18639	0.0196078431372549	0.65732120186204	0.787026061848434	0.861110444638151
GO:0140767	enzyme-substrate adaptor activity	3/556	139/18639	0.0215827338129496	0.723526214999224	0.788055889464506	0.861110444638151
GO:0140097	catalytic activity, acting on DNA	8/556	336/18639	0.0238095238095238	0.798175745118191	0.788368238127622	0.861110444638151
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/556	52/18639	0.0192307692307692	0.644680409518539	0.793396489522862	0.862985091901264
GO:0004864	protein phosphatase inhibitor activity	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0005003	ephrin receptor activity	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0005005	transmembrane-ephrin receptor activity	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0005544	calcium-dependent phospholipid binding	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0008146	sulfotransferase activity	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0016860	intramolecular oxidoreductase activity	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0034212	protein N-acetyltransferase activity	1/556	53/18639	0.0188679245283019	0.632516628206868	0.799576698907125	0.862985091901264
GO:0020037	heme binding	3/556	142/18639	0.0211267605633803	0.708240449893606	0.799935952766925	0.862985091901264
GO:0008237	metallopeptidase activity	4/556	184/18639	0.0217391304347826	0.728769158586174	0.802690531039223	0.864805621668562
GO:0017069	snRNA binding	1/556	54/18639	0.0185185185185185	0.620803357314149	0.805572359910441	0.864805621668562
GO:0050661	NADP binding	1/556	54/18639	0.0185185185185185	0.620803357314149	0.805572359910441	0.864805621668562
GO:0051287	NAD binding	1/556	54/18639	0.0185185185185185	0.620803357314149	0.805572359910441	0.864805621668562
GO:0098632	cell-cell adhesion mediator activity	1/556	55/18639	0.0181818181818182	0.609516023544801	0.811388973732867	0.869983771101581
GO:0015171	amino acid transmembrane transporter activity	2/556	102/18639	0.0196078431372549	0.65732120186204	0.812402544371349	0.870005658764427
GO:0046943	carboxylic acid transmembrane transporter activity	4/556	188/18639	0.0212765957446809	0.713263431807745	0.81589904620635	0.870705504890242
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	5/556	229/18639	0.0218340611353712	0.731951556658603	0.816915249980778	0.870705504890242
GO:0019212	phosphatase inhibitor activity	1/556	56/18639	0.0178571428571429	0.598631808838643	0.81703187787646	0.870705504890242
GO:0170055	lipid transmembrane transporter activity	1/556	56/18639	0.0178571428571429	0.598631808838643	0.81703187787646	0.870705504890242
GO:0005342	organic acid transmembrane transporter activity	4/556	189/18639	0.0211640211640212	0.70948955121617	0.819085619464274	0.871833539065254
GO:0004601	peroxidase activity	1/556	57/18639	0.0175438596491228	0.588129496402878	0.822506251007854	0.874411985294757
GO:0004497	monooxygenase activity	2/556	106/18639	0.0188679245283019	0.632516628206868	0.82894473000596	0.880188586042692
GO:0001786	phosphatidylserine binding	1/556	59/18639	0.0169491525423729	0.568192903304475	0.832969352893907	0.883391226555765
GO:0046906	tetrapyrrole binding	3/556	152/18639	0.0197368421052632	0.661645683453237	0.835570202580353	0.885077989673989
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/556	60/18639	0.0166666666666667	0.558723021582734	0.837967686574799	0.886545523477686
GO:0019905	syntaxin binding	1/556	61/18639	0.0163934426229508	0.549563627786296	0.842816707849594	0.890600043517786
GO:0004222	metalloendopeptidase activity	2/556	110/18639	0.0181818181818182	0.609516023544801	0.844162332300294	0.890947232644648
GO:0016829	lyase activity	4/556	200/18639	0.02	0.670467625899281	0.851222345925274	0.896322219541096
GO:0005200	structural constituent of cytoskeleton	2/556	112/18639	0.0178571428571429	0.598631808838643	0.851301468787891	0.896322219541096
GO:0015079	potassium ion transmembrane transporter activity	3/556	160/18639	0.01875	0.628563399280575	0.860012435764493	0.904156735287507
GO:0160215	deacylase activity	1/556	65/18639	0.0153846153846154	0.515744327614831	0.860806754828517	0.904156735287507
GO:0016500	protein-hormone receptor activity	1/556	67/18639	0.0149253731343284	0.500348974551702	0.869015555881942	0.911685780781535
GO:0015081	sodium ion transmembrane transporter activity	3/556	164/18639	0.0182926829268293	0.613232584663976	0.870996134702798	0.912521159163929
GO:0005548	phospholipid transporter activity	1/556	68/18639	0.0147058823529412	0.49299090139653	0.87293690796732	0.912521159163929
GO:0140223	general transcription initiation factor activity	1/556	68/18639	0.0147058823529412	0.49299090139653	0.87293690796732	0.912521159163929
GO:0008080	N-acetyltransferase activity	1/556	69/18639	0.0144927536231884	0.485846105724116	0.876741069249436	0.915405454901676
GO:0015108	chloride transmembrane transporter activity	2/556	121/18639	0.0165289256198347	0.554105475949819	0.879876448754354	0.917072562947435
GO:0016782	transferase activity, transferring sulphur-containing groups	1/556	70/18639	0.0142857142857143	0.478905447070915	0.880431535889033	0.917072562947435
GO:0140299	molecular sensor activity	1/556	71/18639	0.0140845070422535	0.472160299929071	0.884011699928329	0.919708134367241
GO:0031491	nucleosome binding	1/556	74/18639	0.0135135135135135	0.453018666148163	0.894122799449631	0.929124047826663
GO:0003735	structural constituent of ribosome	3/556	175/18639	0.0171428571428571	0.574686536485098	0.897369008931576	0.930290238845042
GO:0022832	voltage-gated channel activity	3/556	175/18639	0.0171428571428571	0.574686536485098	0.897369008931576	0.930290238845042
GO:0016298	lipase activity	2/556	130/18639	0.0153846153846154	0.515744327614831	0.903306552750475	0.93533870001113
GO:0005179	hormone activity	2/556	132/18639	0.0151515151515152	0.507930019620667	0.907899356389774	0.938984458320475
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3/556	181/18639	0.0165745856353591	0.555636154060177	0.909615784797753	0.939650268258056
GO:0000049	tRNA binding	1/556	80/18639	0.0125	0.41904226618705	0.911781538149696	0.940778124168591
GO:0005254	chloride channel activity	1/556	83/18639	0.0120481927710843	0.40389616018029	0.919475461934222	0.947600593711033
GO:0004527	exonuclease activity	1/556	84/18639	0.0119047619047619	0.399087872559096	0.921888247187755	0.948970745636279
GO:0046873	metal ion transmembrane transporter activity	9/556	450/18639	0.02	0.670467625899281	0.923729527551111	0.949750077622973
GO:0022843	voltage-gated monoatomic cation channel activity	2/556	143/18639	0.013986013986014	0.468858479649847	0.929714608215247	0.954783114650125
GO:0072341	modified amino acid binding	1/556	91/18639	0.010989010989011	0.368388805439165	0.936873294547287	0.9610082037745
GO:0042393	histone binding	4/556	247/18639	0.0161943319838057	0.542888765910349	0.939448163121672	0.96140751912111
GO:0008509	monoatomic anion transmembrane transporter activity	2/556	149/18639	0.0134228187919463	0.449978272415625	0.93945757576218	0.96140751912111
GO:0019842	vitamin binding	2/556	150/18639	0.0133333333333333	0.446978417266187	0.940951425427975	0.961812658897207
GO:0016410	N-acyltransferase activity	1/556	94/18639	0.0106382978723404	0.356631715903873	0.942382021256492	0.962152273450684
GO:0016407	acetyltransferase activity	1/556	96/18639	0.0104166666666667	0.349201888489209	0.945785224536991	0.964502743532485
GO:0005249	voltage-gated potassium channel activity	1/556	98/18639	0.0102040816326531	0.342075319336368	0.948987757903803	0.966643344097362
GO:0005253	monoatomic anion channel activity	1/556	103/18639	0.00970873786407767	0.32546972131033	0.956191981396295	0.972850378284732
GO:0000149	SNARE binding	1/556	106/18639	0.00943396226415094	0.316258314103434	0.960017270666552	0.975609198496403
GO:0019888	protein phosphatase regulator activity	1/556	107/18639	0.00934579439252336	0.313302628924897	0.961216774120358	0.975696285202125
GO:0022836	gated channel activity	5/556	318/18639	0.0157232704402516	0.52709719017239	0.962627449963661	0.975761802777369
GO:0004620	phospholipase activity	1/556	109/18639	0.00917431192660551	0.307553956834532	0.963509086075826	0.975761802777369
GO:0005244	voltage-gated monoatomic ion channel activity	2/556	173/18639	0.0115606936416185	0.387553540982243	0.967030064598983	0.97819669352045
GO:0008528	G protein-coupled peptide receptor activity	1/556	122/18639	0.00819672131147541	0.274781813893148	0.97544560154677	0.984363700133854
GO:0015276	ligand-gated monoatomic ion channel activity	2/556	186/18639	0.010752688172043	0.360466465537248	0.976427733307762	0.984363700133854
GO:0005267	potassium channel activity	1/556	124/18639	0.00806451612903226	0.270349849152936	0.976898065640745	0.984363700133854
GO:0022834	ligand-gated channel activity	2/556	188/18639	0.0106382978723404	0.356631715903873	0.97762148300965	0.984363700133854
GO:0001653	peptide receptor activity	1/556	128/18639	0.0078125	0.261901416366906	0.97955073400533	0.985173872547266
GO:0099094	ligand-gated monoatomic cation channel activity	1/556	136/18639	0.00735294117647059	0.246495450698265	0.983978557875477	0.988492220984998
GO:0140101	catalytic activity, acting on a tRNA	1/556	139/18639	0.00719424460431655	0.241175404999741	0.985379959839964	0.988766145268967
GO:0015293	symporter activity	1/556	146/18639	0.00684931506849315	0.229612200650439	0.988192280927132	0.990453590494471
GO:0045182	translation regulator activity	4/556	356/18639	0.0112359550561798	0.376667205561394	0.994332995064901	0.99546937563069
GO:0030371	translation repressor activity	2/556	329/18639	0.0060790273556231	0.20378955194507	0.999513582335915	0.999513582335915