ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0023023 MHC protein complex binding 6/124 37/18639 0.162162162162162 24.3753269398431 1.50727589597538e-07 5.75779392262595e-05 GO:0023026 MHC class II protein complex binding 5/124 27/18639 0.185185185185185 27.8360215053763 8.62746757446478e-07 0.000164784630672277 GO:0042605 peptide antigen binding 4/124 45/18639 0.0888888888888889 13.3612903225806 0.000225137931276525 0.0286675632492108 GO:0140375 immune receptor activity 6/124 156/18639 0.0384615384615385 5.78132754342432 0.000618804304623948 0.059095811091587 GO:0004540 RNA nuclease activity 5/124 121/18639 0.0413223140495868 6.21134364169555 0.00129160727480438 0.0810958389232948 GO:0042277 peptide binding 7/124 249/18639 0.0281124497991968 4.22570928876798 0.00139627197286813 0.0810958389232948 GO:0031072 heat shock protein binding 5/124 131/18639 0.0381679389312977 5.73719527210047 0.00183453782190058 0.0810958389232948 GO:0032395 MHC class II receptor activity 2/124 10/18639 0.2 30.0629032258065 0.00190787086478013 0.0810958389232948 GO:0001618 virus receptor activity 4/124 81/18639 0.0493827160493827 7.42293906810036 0.00209152065684015 0.0810958389232948 GO:0140272 exogenous protein binding 4/124 82/18639 0.0487804878048781 7.3324154209284 0.00218760978801271 0.0810958389232948 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 8/124 349/18639 0.0229226361031519 3.44560495424716 0.00233856465063743 0.0810958389232948 GO:0017080 sodium channel regulator activity 3/124 41/18639 0.0731707317073171 10.9986231313926 0.00254751326460612 0.0810958389232948 GO:0035259 nuclear glucocorticoid receptor binding 2/124 12/18639 0.166666666666667 25.0524193548387 0.00277394606973253 0.0815113383567559 GO:0140297 DNA-binding transcription factor binding 9/124 488/18639 0.0184426229508197 2.77219394500264 0.00535414162255649 0.146091578558327 GO:0004519 endonuclease activity 4/124 127/18639 0.031496062992126 4.73431546863094 0.0102896723614436 0.225474881031405 GO:0042826 histone deacetylase binding 4/124 127/18639 0.031496062992126 4.73431546863094 0.0102896723614436 0.225474881031405 GO:0004521 RNA endonuclease activity 3/124 73/18639 0.0410958904109589 6.17730888201502 0.0127454142831113 0.225474881031405 GO:0030247 polysaccharide binding 2/124 26/18639 0.0769230769230769 11.5626550868486 0.0128549559916088 0.225474881031405 GO:0002020 protease binding 4/124 136/18639 0.0294117647058824 4.42101518026565 0.0129725234351107 0.225474881031405 GO:0044325 transmembrane transporter binding 4/124 136/18639 0.0294117647058824 4.42101518026565 0.0129725234351107 0.225474881031405 GO:0140789 histone phosphatase activity 4/124 136/18639 0.0294117647058824 4.42101518026565 0.0129725234351107 0.225474881031405 GO:0004518 nuclease activity 5/124 209/18639 0.0239234449760766 3.59604105571848 0.012985464352594 0.225474881031405 GO:0044183 protein folding chaperone 3/124 75/18639 0.04 6.01258064516129 0.0137058316256951 0.227635986131111 GO:0019955 cytokine binding 4/124 144/18639 0.0277777777777778 4.17540322580645 0.0157008145555213 0.249904631675381 GO:0001540 amyloid-beta binding 3/124 83/18639 0.036144578313253 5.43305479984454 0.0179510735343444 0.264460257372022 GO:0005164 tumor necrosis factor receptor binding 2/124 31/18639 0.0645161290322581 9.69771071800208 0.0179999128054256 0.264460257372022 GO:0030515 snoRNA binding 2/124 32/18639 0.0625 9.39465725806452 0.0191173703851684 0.270475388412383 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/124 89/18639 0.0337078651685393 5.06678144255165 0.0215626230465466 0.273565664153521 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/124 89/18639 0.0337078651685393 5.06678144255165 0.0215626230465466 0.273565664153521 GO:0099106 ion channel regulator activity 4/124 160/18639 0.025 3.75786290322581 0.0221780866422798 0.273565664153521 GO:0140793 histone H2AXY142 phosphatase activity 3/124 90/18639 0.0333333333333333 5.01048387096774 0.0222003549443957 0.273565664153521 GO:0016247 channel regulator activity 4/124 168/18639 0.0238095238095238 3.57891705069124 0.0259466879629968 0.296974370147485 GO:0004896 cytokine receptor activity 3/124 96/18639 0.03125 4.69732862903226 0.0262417113686762 0.296974370147485 GO:0141108 transporter regulator activity 4/124 170/18639 0.0235294117647059 3.53681214421252 0.0269453574288662 0.296974370147485 GO:0004725 protein tyrosine phosphatase activity 3/124 98/18639 0.0306122448979592 4.60146477946017 0.0276706199377362 0.296974370147485 GO:0003823 antigen binding 4/124 174/18639 0.0229885057471264 3.45550611790879 0.0290111743049572 0.296974370147485 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/124 40/18639 0.05 7.51572580645161 0.0290475382088396 0.296974370147485 GO:0004721 phosphoprotein phosphatase activity 4/124 175/18639 0.0228571428571429 3.43576036866359 0.0295419530513205 0.296974370147485 GO:0042287 MHC protein binding 2/124 41/18639 0.0487804878048781 7.3324154209284 0.0304065138470054 0.297827904860412 GO:0061135 endopeptidase regulator activity 4/124 184/18639 0.0217391304347826 3.26770687237027 0.0345785269108354 0.330224931998478 GO:0005126 cytokine receptor binding 5/124 275/18639 0.0181818181818182 2.73299120234604 0.0368372873753886 0.331913271225018 GO:0030246 carbohydrate binding 5/124 280/18639 0.0178571428571429 2.68418778801843 0.0393135916718144 0.331913271225018 GO:0038187 pattern recognition receptor activity 2/124 48/18639 0.0416666666666667 6.26310483870968 0.0405934991269194 0.331913271225018 GO:0032813 tumor necrosis factor receptor superfamily binding 2/124 50/18639 0.04 6.01258064516129 0.0437095936915945 0.331913271225018 GO:0005080 protein kinase C binding 2/124 52/18639 0.0384615384615385 5.78132754342432 0.0469117423840951 0.331913271225018 GO:0003714 transcription corepressor activity 4/124 204/18639 0.0196078431372549 2.94734345351044 0.0474568308308398 0.331913271225018 GO:0003712 transcription coregulator activity 7/124 495/18639 0.0141414141414141 2.12565982404692 0.0475395440081806 0.331913271225018 GO:0005246 calcium channel regulator activity 2/124 53/18639 0.0377358490566038 5.67224589166159 0.0485442129705863 0.331913271225018 GO:0140313 molecular sequestering activity 2/124 55/18639 0.0363636363636364 5.46598240469208 0.051870230230249 0.331913271225018 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/124 128/18639 0.0234375 3.52299647177419 0.0539105471505104 0.331913271225018 GO:0005179 hormone activity 3/124 132/18639 0.0227272727272727 3.41623900293255 0.0580672707601521 0.331913271225018 GO:0004879 nuclear receptor activity 2/124 59/18639 0.0338983050847458 5.09540732640787 0.0587571812538589 0.331913271225018 GO:0098531 ligand-modulated transcription factor activity 2/124 60/18639 0.0333333333333333 5.01048387096774 0.0605259448881415 0.331913271225018 GO:0061134 peptidase regulator activity 4/124 226/18639 0.0176991150442478 2.66043391378818 0.0643030756617752 0.331913271225018 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0005528 FK506 binding 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0008401 retinoic acid 4-hydroxylase activity 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0015279 store-operated calcium channel activity 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0047429 nucleoside triphosphate diphosphatase activity 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/124 10/18639 0.1 15.0314516129032 0.0645855899029484 0.331913271225018 GO:0003953 NAD+ nucleosidase activity 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0034511 U3 snoRNA binding 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0042608 T cell receptor binding 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0045294 alpha-catenin binding 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0050998 nitric-oxide synthase binding 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0097493 structural molecule activity conferring elasticity 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/124 11/18639 0.0909090909090909 13.6649560117302 0.0708119781606131 0.331913271225018 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/124 67/18639 0.0298507462686567 4.48700048146365 0.0733985437423822 0.331913271225018 GO:0005527 macrolide binding 1/124 12/18639 0.0833333333333333 12.5262096774194 0.0769972538052387 0.331913271225018 GO:0045295 gamma-catenin binding 1/124 12/18639 0.0833333333333333 12.5262096774194 0.0769972538052387 0.331913271225018 GO:0070008 serine-type exopeptidase activity 1/124 12/18639 0.0833333333333333 12.5262096774194 0.0769972538052387 0.331913271225018 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/124 12/18639 0.0833333333333333 12.5262096774194 0.0769972538052387 0.331913271225018 GO:0033218 amide binding 4/124 247/18639 0.0161943319838057 2.43424317617866 0.0829332886771714 0.331913271225018 GO:0008035 high-density lipoprotein particle binding 1/124 13/18639 0.0769230769230769 11.5626550868486 0.0831416861093213 0.331913271225018 GO:0031432 titin binding 1/124 13/18639 0.0769230769230769 11.5626550868486 0.0831416861093213 0.331913271225018 GO:0031994 insulin-like growth factor I binding 1/124 13/18639 0.0769230769230769 11.5626550868486 0.0831416861093213 0.331913271225018 GO:0070700 BMP receptor binding 1/124 13/18639 0.0769230769230769 11.5626550868486 0.0831416861093213 0.331913271225018 GO:0008191 metalloendopeptidase inhibitor activity 1/124 14/18639 0.0714285714285714 10.7367511520737 0.0892455425960844 0.331913271225018 GO:0008392 arachidonate epoxygenase activity 1/124 14/18639 0.0714285714285714 10.7367511520737 0.0892455425960844 0.331913271225018 GO:0016530 metallochaperone activity 1/124 14/18639 0.0714285714285714 10.7367511520737 0.0892455425960844 0.331913271225018 GO:0031404 chloride ion binding 1/124 14/18639 0.0714285714285714 10.7367511520737 0.0892455425960844 0.331913271225018 GO:0019887 protein kinase regulator activity 4/124 255/18639 0.0156862745098039 2.35787476280835 0.0906598952979191 0.331913271225018 GO:0004866 endopeptidase inhibitor activity 3/124 161/18639 0.0186335403726708 2.8008916048888 0.0924207808441079 0.331913271225018 GO:0005041 low-density lipoprotein particle receptor activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0005523 tropomyosin binding 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0017081 chloride channel regulator activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0031386 protein tag activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0033130 acetylcholine receptor binding 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0061578 K63-linked deubiquitinase activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0140776 protein-containing complex destabilizing activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0141047 molecular tag activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0141050 histone H3K deacetylase activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0141051 histone H4K deacetylase activity 1/124 15/18639 0.0666666666666667 10.0209677419355 0.0953090890507464 0.331913271225018 GO:0046332 SMAD binding 2/124 79/18639 0.0253164556962025 3.80543078807677 0.0972402983055852 0.331913271225018 GO:0046982 protein heterodimerization activity 5/124 369/18639 0.013550135501355 2.036782061369 0.100180296379277 0.331913271225018 GO:0005159 insulin-like growth factor receptor binding 1/124 16/18639 0.0625 9.39465725806452 0.101332589531723 0.331913271225018 GO:0005521 lamin binding 1/124 16/18639 0.0625 9.39465725806452 0.101332589531723 0.331913271225018 GO:0008296 3'-5'-DNA exonuclease activity 1/124 16/18639 0.0625 9.39465725806452 0.101332589531723 0.331913271225018 GO:0008391 arachidonate monooxygenase activity 1/124 16/18639 0.0625 9.39465725806452 0.101332589531723 0.331913271225018 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/124 16/18639 0.0625 9.39465725806452 0.101332589531723 0.331913271225018 GO:0033192 calmodulin-dependent protein phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:0140791 histone H2AXS140 phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/124 81/18639 0.0246913580246914 3.71146953405018 0.101404409147995 0.331913271225018 GO:0030414 peptidase inhibitor activity 3/124 169/18639 0.0177514792899408 2.66830502004199 0.103098118663036 0.331913271225018 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/124 82/18639 0.024390243902439 3.6662077104642 0.103504897090105 0.331913271225018 GO:0033549 MAP kinase phosphatase activity 2/124 82/18639 0.024390243902439 3.6662077104642 0.103504897090105 0.331913271225018 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/124 83/18639 0.0240963855421687 3.62203653322969 0.105617337177901 0.331913271225018 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/124 17/18639 0.0588235294117647 8.84203036053131 0.107316306381751 0.331913271225018 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/124 17/18639 0.0588235294117647 8.84203036053131 0.107316306381751 0.331913271225018 GO:0017110 nucleoside diphosphate phosphatase activity 1/124 17/18639 0.0588235294117647 8.84203036053131 0.107316306381751 0.331913271225018 GO:0019198 transmembrane receptor protein phosphatase activity 1/124 17/18639 0.0588235294117647 8.84203036053131 0.107316306381751 0.331913271225018 GO:0030548 acetylcholine receptor regulator activity 1/124 17/18639 0.0588235294117647 8.84203036053131 0.107316306381751 0.331913271225018 GO:0017018 myosin phosphatase activity 2/124 84/18639 0.0238095238095238 3.57891705069124 0.107741480711786 0.331913271225018 GO:0016791 phosphatase activity 4/124 273/18639 0.0146520146520147 2.20241049273307 0.109249638335016 0.333866894751809 GO:0030228 lipoprotein particle receptor activity 1/124 18/18639 0.0555555555555556 8.3508064516129 0.113260500238945 0.340673315679346 GO:0099602 neurotransmitter receptor regulator activity 1/124 18/18639 0.0555555555555556 8.3508064516129 0.113260500238945 0.340673315679346 GO:0140098 catalytic activity, acting on RNA 5/124 387/18639 0.0129198966408269 1.942048012003 0.116239717788026 0.34690290777364 GO:0005520 insulin-like growth factor binding 1/124 19/18639 0.0526315789473684 7.91129032258065 0.119165430047782 0.347490032658419 GO:0030506 ankyrin binding 1/124 19/18639 0.0526315789473684 7.91129032258065 0.119165430047782 0.347490032658419 GO:0043395 heparan sulfate proteoglycan binding 1/124 19/18639 0.0526315789473684 7.91129032258065 0.119165430047782 0.347490032658419 GO:0008237 metallopeptidase activity 3/124 184/18639 0.016304347826087 2.4507801542777 0.124349158775375 0.356432663229462 GO:0019207 kinase regulator activity 4/124 287/18639 0.0139372822299652 2.09497583455097 0.124798968406551 0.356432663229462 GO:0016505 peptidase activator activity involved in apoptotic process 1/124 20/18639 0.05 7.51572580645161 0.125031353070021 0.356432663229462 GO:0005248 voltage-gated sodium channel activity 1/124 21/18639 0.0476190476190476 7.15783410138249 0.130858524895538 0.367558503750703 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/124 21/18639 0.0476190476190476 7.15783410138249 0.130858524895538 0.367558503750703 GO:0004407 histone deacetylase activity 1/124 22/18639 0.0454545454545455 6.8324780058651 0.136647199453115 0.37285164422207 GO:0031683 G-protein beta/gamma-subunit complex binding 1/124 22/18639 0.0454545454545455 6.8324780058651 0.136647199453115 0.37285164422207 GO:0033558 protein lysine deacetylase activity 1/124 22/18639 0.0454545454545455 6.8324780058651 0.136647199453115 0.37285164422207 GO:0061133 endopeptidase activator activity 1/124 22/18639 0.0454545454545455 6.8324780058651 0.136647199453115 0.37285164422207 GO:0008236 serine-type peptidase activity 3/124 194/18639 0.0154639175257732 2.32445128034586 0.139326713401872 0.377186963593348 GO:0016849 phosphorus-oxygen lyase activity 1/124 23/18639 0.0434782608695652 6.53541374474053 0.142397629021134 0.377186963593348 GO:0140103 catalytic activity, acting on a glycoprotein 1/124 23/18639 0.0434782608695652 6.53541374474053 0.142397629021134 0.377186963593348 GO:0031625 ubiquitin protein ligase binding 4/124 302/18639 0.0132450331125828 1.99092074343089 0.142438096388675 0.377186963593348 GO:0004857 enzyme inhibitor activity 5/124 416/18639 0.0120192307692308 1.8066648573201 0.144505996195116 0.377186963593348 GO:0017171 serine hydrolase activity 3/124 198/18639 0.0151515151515152 2.2774926686217 0.14548286683741 0.377186963593348 GO:0008238 exopeptidase activity 2/124 102/18639 0.0196078431372549 2.94734345351044 0.147709687639828 0.377186963593348 GO:0019957 C-C chemokine binding 1/124 24/18639 0.0416666666666667 6.26310483870968 0.148110064238226 0.377186963593348 GO:0035035 histone acetyltransferase binding 1/124 24/18639 0.0416666666666667 6.26310483870968 0.148110064238226 0.377186963593348 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/124 24/18639 0.0416666666666667 6.26310483870968 0.148110064238226 0.377186963593348 GO:0004722 protein serine/threonine phosphatase activity 2/124 103/18639 0.0194174757281553 2.9187284685249 0.150012431617023 0.379005006912804 GO:0008483 transaminase activity 1/124 25/18639 0.04 6.01258064516129 0.153784754113834 0.379005006912804 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/124 25/18639 0.04 6.01258064516129 0.153784754113834 0.379005006912804 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/124 25/18639 0.04 6.01258064516129 0.153784754113834 0.379005006912804 GO:0120020 cholesterol transfer activity 1/124 25/18639 0.04 6.01258064516129 0.153784754113834 0.379005006912804 GO:0019888 protein phosphatase regulator activity 2/124 107/18639 0.0186915887850467 2.80961712390714 0.159294167399506 0.379358756255675 GO:0004529 DNA exonuclease activity 1/124 26/18639 0.0384615384615385 5.78132754342432 0.159421946038724 0.379358756255675 GO:0008157 protein phosphatase 1 binding 1/124 26/18639 0.0384615384615385 5.78132754342432 0.159421946038724 0.379358756255675 GO:0030507 spectrin binding 1/124 26/18639 0.0384615384615385 5.78132754342432 0.159421946038724 0.379358756255675 GO:0070412 R-SMAD binding 1/124 26/18639 0.0384615384615385 5.78132754342432 0.159421946038724 0.379358756255675 GO:0004674 protein serine/threonine kinase activity 5/124 433/18639 0.0115473441108545 1.73573344259852 0.162340349634025 0.379358756255675 GO:0001671 ATPase activator activity 1/124 27/18639 0.037037037037037 5.56720430107527 0.165021885795409 0.379358756255675 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/124 27/18639 0.037037037037037 5.56720430107527 0.165021885795409 0.379358756255675 GO:0005044 scavenger receptor activity 1/124 27/18639 0.037037037037037 5.56720430107527 0.165021885795409 0.379358756255675 GO:0008320 protein transmembrane transporter activity 1/124 27/18639 0.037037037037037 5.56720430107527 0.165021885795409 0.379358756255675 GO:0004222 metalloendopeptidase activity 2/124 110/18639 0.0181818181818182 2.73299120234604 0.166324395706878 0.379358756255675 GO:0044389 ubiquitin-like protein ligase binding 4/124 322/18639 0.0124223602484472 1.86726106992587 0.167385485975917 0.379358756255675 GO:0045499 chemorepellent activity 1/124 28/18639 0.0357142857142857 5.36837557603687 0.170584817568533 0.379358756255675 GO:0051019 mitogen-activated protein kinase binding 1/124 28/18639 0.0357142857142857 5.36837557603687 0.170584817568533 0.379358756255675 GO:0005200 structural constituent of cytoskeleton 2/124 112/18639 0.0178571428571429 2.68418778801843 0.17104124140577 0.379358756255675 GO:0003779 actin binding 5/124 443/18639 0.0112866817155756 1.69655210077915 0.173230953769552 0.379358756255675 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/124 29/18639 0.0344827586206897 5.18325917686318 0.176110983955159 0.379358756255675 GO:0016769 transferase activity, transferring nitrogenous groups 1/124 30/18639 0.0333333333333333 5.01048387096774 0.181600625975017 0.379358756255675 GO:0033612 receptor serine/threonine kinase binding 1/124 30/18639 0.0333333333333333 5.01048387096774 0.181600625975017 0.379358756255675 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/124 30/18639 0.0333333333333333 5.01048387096774 0.181600625975017 0.379358756255675 GO:0070566 adenylyltransferase activity 1/124 30/18639 0.0333333333333333 5.01048387096774 0.181600625975017 0.379358756255675 GO:0019208 phosphatase regulator activity 2/124 117/18639 0.0170940170940171 2.56947890818859 0.182928014293433 0.379358756255675 GO:0070325 lipoprotein particle receptor binding 1/124 31/18639 0.032258064516129 4.84885535900104 0.18705398308067 0.379358756255675 GO:0022884 macromolecule transmembrane transporter activity 1/124 32/18639 0.03125 4.69732862903226 0.192471293167622 0.379358756255675 GO:0071813 lipoprotein particle binding 1/124 32/18639 0.03125 4.69732862903226 0.192471293167622 0.379358756255675 GO:0071814 protein-lipid complex binding 1/124 32/18639 0.03125 4.69732862903226 0.192471293167622 0.379358756255675 GO:0120015 sterol transfer activity 1/124 32/18639 0.03125 4.69732862903226 0.192471293167622 0.379358756255675 GO:0051082 unfolded protein binding 2/124 121/18639 0.0165289256198347 2.48453745667822 0.192523465285499 0.379358756255675 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/124 33/18639 0.0303030303030303 4.5549853372434 0.197852792584359 0.379358756255675 GO:0019956 chemokine binding 1/124 33/18639 0.0303030303030303 4.5549853372434 0.197852792584359 0.379358756255675 GO:0071889 14-3-3 protein binding 1/124 33/18639 0.0303030303030303 4.5549853372434 0.197852792584359 0.379358756255675 GO:0140311 protein sequestering activity 1/124 33/18639 0.0303030303030303 4.5549853372434 0.197852792584359 0.379358756255675 GO:0140416 transcription regulator inhibitor activity 1/124 33/18639 0.0303030303030303 4.5549853372434 0.197852792584359 0.379358756255675 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/124 34/18639 0.0294117647058824 4.42101518026565 0.203198716142326 0.379358756255675 GO:0005125 cytokine activity 3/124 234/18639 0.0128205128205128 1.92710918114144 0.204410129747482 0.379358756255675 GO:0000175 3'-5'-RNA exonuclease activity 1/124 35/18639 0.0285714285714286 4.29470046082949 0.208509297125844 0.379358756255675 GO:0005154 epidermal growth factor receptor binding 1/124 35/18639 0.0285714285714286 4.29470046082949 0.208509297125844 0.379358756255675 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/124 36/18639 0.0277777777777778 4.17540322580645 0.213784767301956 0.379358756255675 GO:0005484 SNAP receptor activity 1/124 36/18639 0.0277777777777778 4.17540322580645 0.213784767301956 0.379358756255675 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/124 36/18639 0.0277777777777778 4.17540322580645 0.213784767301956 0.379358756255675 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/124 36/18639 0.0277777777777778 4.17540322580645 0.213784767301956 0.379358756255675 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/124 36/18639 0.0277777777777778 4.17540322580645 0.213784767301956 0.379358756255675 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/124 130/18639 0.0153846153846154 2.31253101736973 0.214336044313712 0.379358756255675 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/124 130/18639 0.0153846153846154 2.31253101736973 0.214336044313712 0.379358756255675 GO:0019213 deacetylase activity 1/124 37/18639 0.027027027027027 4.06255448997385 0.219025356930218 0.379358756255675 GO:0043394 proteoglycan binding 1/124 37/18639 0.027027027027027 4.06255448997385 0.219025356930218 0.379358756255675 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/124 243/18639 0.0123456790123457 1.85573476702509 0.219936848308117 0.379358756255675 GO:0106310 protein serine kinase activity 4/124 361/18639 0.0110803324099723 1.66553480475382 0.219945375344927 0.379358756255675 GO:0042578 phosphoric ester hydrolase activity 4/124 363/18639 0.0110192837465565 1.65635830445215 0.222756430489125 0.379358756255675 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0004711 ribosomal protein S6 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0035175 histone H3S10 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0035979 histone H2AXS139 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0044022 histone H3S28 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0044023 histone H4S1 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0044024 histone H2AS1 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0044025 histone H2BS14 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0072354 histone H3T3 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0072371 histone H2AS121 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0140823 histone H2BS36 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0140855 histone H3S57 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0140995 histone H2A kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0140997 histone H4 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0140998 histone H2B kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:1990244 histone H2AT120 kinase activity 3/124 245/18639 0.0122448979591837 1.84058591178407 0.223420512758248 0.379358756255675 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/124 38/18639 0.0263157894736842 3.95564516129032 0.224231294772421 0.379358756255675 GO:0004677 DNA-dependent protein kinase activity 3/124 246/18639 0.0121951219512195 1.8331038552321 0.225166551210914 0.379358756255675 GO:0140857 histone H3T45 kinase activity 3/124 246/18639 0.0121951219512195 1.8331038552321 0.225166551210914 0.379358756255675 GO:0035402 histone H3T11 kinase activity 3/124 247/18639 0.0121457489878543 1.825682382134 0.226915320832231 0.379358756255675 GO:0035403 histone H3T6 kinase activity 3/124 247/18639 0.0121457489878543 1.825682382134 0.226915320832231 0.379358756255675 GO:0004679 AMP-activated protein kinase activity 3/124 248/18639 0.0120967741935484 1.81832075962539 0.228666767141743 0.379358756255675 GO:0019838 growth factor binding 2/124 136/18639 0.0147058823529412 2.21050759013283 0.229006261623163 0.379358756255675 GO:0000217 DNA secondary structure binding 1/124 39/18639 0.0256410256410256 3.85421836228288 0.229402808102254 0.379358756255675 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/124 39/18639 0.0256410256410256 3.85421836228288 0.229402808102254 0.379358756255675 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/124 39/18639 0.0256410256410256 3.85421836228288 0.229402808102254 0.379358756255675 GO:0016922 nuclear receptor binding 2/124 137/18639 0.0145985401459854 2.19437249823405 0.231458649804679 0.381108638902532 GO:0004532 RNA exonuclease activity 1/124 40/18639 0.025 3.75786290322581 0.234540122714906 0.382596508368681 GO:0140662 ATP-dependent protein folding chaperone 1/124 40/18639 0.025 3.75786290322581 0.234540122714906 0.382596508368681 GO:0030295 protein kinase activator activity 2/124 139/18639 0.0143884892086331 2.16279879322349 0.236368523494787 0.382596508368681 GO:0070851 growth factor receptor binding 2/124 139/18639 0.0143884892086331 2.16279879322349 0.236368523494787 0.382596508368681 GO:0001530 lipopolysaccharide binding 1/124 41/18639 0.024390243902439 3.6662077104642 0.239643462936603 0.384637827066312 GO:0140318 protein transporter activity 1/124 41/18639 0.024390243902439 3.6662077104642 0.239643462936603 0.384637827066312 GO:0003713 transcription coactivator activity 3/124 256/18639 0.01171875 1.7614982358871 0.242768230406192 0.387821789047092 GO:0020037 heme binding 2/124 142/18639 0.0140845070422535 2.11710586097229 0.243744144378042 0.387821789047092 GO:0016859 cis-trans isomerase activity 1/124 42/18639 0.0238095238095238 3.57891705069124 0.24471305163409 0.387821789047092 GO:0019903 protein phosphatase binding 2/124 144/18639 0.0138888888888889 2.08770161290323 0.248666965939642 0.387821789047092 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/124 43/18639 0.0232558139534884 3.4956864216054 0.249749110224043 0.387821789047092 GO:0008200 ion channel inhibitor activity 1/124 43/18639 0.0232558139534884 3.4956864216054 0.249749110224043 0.387821789047092 GO:0008375 acetylglucosaminyltransferase activity 1/124 43/18639 0.0232558139534884 3.4956864216054 0.249749110224043 0.387821789047092 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/124 43/18639 0.0232558139534884 3.4956864216054 0.249749110224043 0.387821789047092 GO:0001223 transcription coactivator binding 1/124 44/18639 0.0227272727272727 3.41623900293255 0.254751858682433 0.390824136613211 GO:0016248 channel inhibitor activity 1/124 44/18639 0.0227272727272727 3.41623900293255 0.254751858682433 0.390824136613211 GO:0030547 signaling receptor inhibitor activity 1/124 44/18639 0.0227272727272727 3.41623900293255 0.254751858682433 0.390824136613211 GO:0019209 kinase activator activity 2/124 148/18639 0.0135135135135135 2.03127724498692 0.258522019417695 0.392148691468609 GO:0008009 chemokine activity 1/124 45/18639 0.0222222222222222 3.34032258064516 0.259721515553817 0.392148691468609 GO:0051539 4 iron, 4 sulfur cluster binding 1/124 45/18639 0.0222222222222222 3.34032258064516 0.259721515553817 0.392148691468609 GO:0141110 transporter inhibitor activity 1/124 45/18639 0.0222222222222222 3.34032258064516 0.259721515553817 0.392148691468609 GO:0004180 carboxypeptidase activity 1/124 46/18639 0.0217391304347826 3.26770687237027 0.264658297960578 0.396468509101729 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/124 46/18639 0.0217391304347826 3.26770687237027 0.264658297960578 0.396468509101729 GO:0046906 tetrapyrrole binding 2/124 152/18639 0.0131578947368421 1.97782258064516 0.268383413341854 0.400478374596048 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/124 48/18639 0.0208333333333333 3.13155241935484 0.274434100813921 0.407913721832365 GO:0060590 ATPase regulator activity 1/124 49/18639 0.0204081632653061 3.06764318630678 0.279273548476719 0.413498044643824 GO:0005272 sodium channel activity 1/124 51/18639 0.0196078431372549 2.94734345351044 0.288856593907978 0.424396995664799 GO:0030544 Hsp70 protein binding 1/124 51/18639 0.0196078431372549 2.94734345351044 0.288856593907978 0.424396995664799 GO:0005178 integrin binding 2/124 161/18639 0.0124223602484472 1.86726106992587 0.290558455080745 0.425261800156493 GO:0004864 protein phosphatase inhibitor activity 1/124 53/18639 0.0188679245283019 2.8361229458308 0.298313233635947 0.430021340562007 GO:0005544 calcium-dependent phospholipid binding 1/124 53/18639 0.0188679245283019 2.8361229458308 0.298313233635947 0.430021340562007 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/124 53/18639 0.0188679245283019 2.8361229458308 0.298313233635947 0.430021340562007 GO:0016860 intramolecular oxidoreductase activity 1/124 53/18639 0.0188679245283019 2.8361229458308 0.298313233635947 0.430021340562007 GO:0015485 cholesterol binding 1/124 54/18639 0.0185185185185185 2.78360215053763 0.302994669072789 0.431880461141065 GO:0017069 snRNA binding 1/124 54/18639 0.0185185185185185 2.78360215053763 0.302994669072789 0.431880461141065 GO:0050661 NADP binding 1/124 54/18639 0.0185185185185185 2.78360215053763 0.302994669072789 0.431880461141065 GO:0005201 extracellular matrix structural constituent 2/124 168/18639 0.0119047619047619 1.78945852534562 0.307755432659803 0.437035595821728 GO:0019212 phosphatase inhibitor activity 1/124 56/18639 0.0178571428571429 2.68418778801843 0.312264794745333 0.441796857750804 GO:0001664 G protein-coupled receptor binding 3/124 297/18639 0.0101010101010101 1.5183284457478 0.316693006397439 0.443363319235601 GO:0004601 peroxidase activity 1/124 57/18639 0.0175438596491228 2.63709677419355 0.31685389044848 0.443363319235601 GO:0016504 peptidase activator activity 1/124 57/18639 0.0175438596491228 2.63709677419355 0.31685389044848 0.443363319235601 GO:0008408 3'-5' exonuclease activity 1/124 58/18639 0.0172413793103448 2.59162958843159 0.321412609509097 0.447875970595203 GO:0015459 potassium channel regulator activity 1/124 59/18639 0.0169491525423729 2.54770366320394 0.325941151375566 0.447875970595203 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/124 59/18639 0.0169491525423729 2.54770366320394 0.325941151375566 0.447875970595203 GO:0031593 polyubiquitin modification-dependent protein binding 1/124 59/18639 0.0169491525423729 2.54770366320394 0.325941151375566 0.447875970595203 GO:0070063 RNA polymerase binding 1/124 59/18639 0.0169491525423729 2.54770366320394 0.325941151375566 0.447875970595203 GO:0004252 serine-type endopeptidase activity 2/124 176/18639 0.0113636363636364 1.70811950146628 0.327311112314387 0.44814639750572 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/124 60/18639 0.0166666666666667 2.50524193548387 0.330439714197387 0.449209860581501 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/124 60/18639 0.0166666666666667 2.50524193548387 0.330439714197387 0.449209860581501 GO:0015026 coreceptor activity 1/124 61/18639 0.0163934426229508 2.46417239555791 0.334908494833564 0.452067296913149 GO:0016836 hydro-lyase activity 1/124 61/18639 0.0163934426229508 2.46417239555791 0.334908494833564 0.452067296913149 GO:0016853 isomerase activity 2/124 180/18639 0.0111111111111111 1.67016129032258 0.337037073798722 0.453338599264478 GO:0004536 DNA nuclease activity 1/124 64/18639 0.015625 2.34866431451613 0.348138093035538 0.466627198384475 GO:0038024 cargo receptor activity 1/124 65/18639 0.0153846153846154 2.31253101736973 0.352489687999931 0.467538405611019 GO:0120013 lipid transfer activity 1/124 65/18639 0.0153846153846154 2.31253101736973 0.352489687999931 0.467538405611019 GO:0160215 deacylase activity 1/124 65/18639 0.0153846153846154 2.31253101736973 0.352489687999931 0.467538405611019 GO:0008235 metalloexopeptidase activity 1/124 66/18639 0.0151515151515152 2.2774926686217 0.356812466006176 0.471634470637922 GO:0019902 phosphatase binding 2/124 190/18639 0.0105263157894737 1.58225806451613 0.361162084932831 0.474735472584821 GO:0003777 microtubule motor activity 1/124 68/18639 0.0147058823529412 2.21050759013283 0.365372327067898 0.474735472584821 GO:0030145 manganese ion binding 1/124 68/18639 0.0147058823529412 2.21050759013283 0.365372327067898 0.474735472584821 GO:0032934 sterol binding 1/124 68/18639 0.0147058823529412 2.21050759013283 0.365372327067898 0.474735472584821 GO:0140223 general transcription initiation factor activity 1/124 68/18639 0.0147058823529412 2.21050759013283 0.365372327067898 0.474735472584821 GO:0140299 molecular sensor activity 1/124 71/18639 0.0140845070422535 2.11710586097229 0.378000683791392 0.488446980325343 GO:0003924 GTPase activity 3/124 331/18639 0.00906344410876133 1.36236721567099 0.378482476901313 0.488446980325343 GO:0005518 collagen binding 1/124 72/18639 0.0138888888888889 2.08770161290323 0.38215449223656 0.489875892732771 GO:0042379 chemokine receptor binding 1/124 72/18639 0.0138888888888889 2.08770161290323 0.38215449223656 0.489875892732771 GO:0016829 lyase activity 2/124 200/18639 0.01 1.50314516129032 0.384962410040443 0.491824885068392 GO:0043539 protein serine/threonine kinase activator activity 1/124 73/18639 0.0136986301369863 2.05910296067167 0.386280783126992 0.491864197181704 GO:0003725 double-stranded RNA binding 1/124 75/18639 0.0133333333333333 2.0041935483871 0.394451534353213 0.500599621670855 GO:0017022 myosin binding 1/124 76/18639 0.0131578947368421 1.97782258064516 0.398496352805066 0.502394741820248 GO:0051536 iron-sulfur cluster binding 1/124 76/18639 0.0131578947368421 1.97782258064516 0.398496352805066 0.502394741820248 GO:0051540 metal cluster binding 1/124 77/18639 0.012987012987013 1.95213657310431 0.402514369949503 0.505791083291809 GO:0051015 actin filament binding 2/124 209/18639 0.00956937799043062 1.43841642228739 0.40605649635793 0.50856912002862 GO:0016835 carbon-oxygen lyase activity 1/124 79/18639 0.0126582278481013 1.90271539403838 0.410470703781393 0.512417675962393 GO:0048306 calcium-dependent protein binding 1/124 80/18639 0.0125 1.8789314516129 0.414409369338026 0.515649443280541 GO:0030971 receptor tyrosine kinase binding 1/124 81/18639 0.0123456790123457 1.85573476702509 0.418321931340401 0.518827849909199 GO:0141003 histone H2AX kinase activity 3/124 354/18639 0.00847457627118644 1.27385183160197 0.419698403176182 0.51885045311748 GO:0140996 histone H3 kinase activity 3/124 357/18639 0.00840336134453781 1.26314719436162 0.42501451539928 0.521841524264491 GO:0030165 PDZ domain binding 1/124 83/18639 0.0120481927710843 1.81101826661485 0.426069429980862 0.521841524264491 GO:0004527 exonuclease activity 1/124 84/18639 0.0119047619047619 1.78945852534562 0.429904706478079 0.521841524264491 GO:0004860 protein kinase inhibitor activity 1/124 84/18639 0.0119047619047619 1.78945852534562 0.429904706478079 0.521841524264491 GO:0051117 ATPase binding 1/124 84/18639 0.0119047619047619 1.78945852534562 0.429904706478079 0.521841524264491 GO:0035173 histone kinase activity 3/124 360/18639 0.00833333333333333 1.25262096774194 0.430314345924908 0.521841524264491 GO:0016209 antioxidant activity 1/124 86/18639 0.0116279069767442 1.7478432108027 0.437499155179652 0.528875561008313 GO:0019210 kinase inhibitor activity 1/124 90/18639 0.0111111111111111 1.67016129032258 0.452388278211039 0.545149281629706 GO:0000287 magnesium ion binding 2/124 230/18639 0.00869565217391304 1.30708274894811 0.453872603102127 0.545218032657272 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/124 91/18639 0.010989010989011 1.65180786954981 0.456049060652239 0.546115176078857 GO:0043178 alcohol binding 1/124 92/18639 0.0108695652173913 1.63385343618513 0.459685566824286 0.548749645396492 GO:0042562 hormone binding 1/124 94/18639 0.0106382978723404 1.59909059711736 0.466886388064926 0.555609346544553 GO:0004867 serine-type endopeptidase inhibitor activity 1/124 95/18639 0.0105263157894737 1.58225806451613 0.470451019387652 0.558112700018891 GO:0043130 ubiquitin binding 1/124 100/18639 0.01 1.50314516129032 0.487922615789033 0.577047799478052 GO:0004175 endopeptidase activity 3/124 405/18639 0.00740740740740741 1.11344086021505 0.507419177471225 0.593601367867168 GO:0000149 SNARE binding 1/124 106/18639 0.00943396226415094 1.4180614729154 0.508135202336555 0.593601367867168 GO:0004497 monooxygenase activity 1/124 106/18639 0.00943396226415094 1.4180614729154 0.508135202336555 0.593601367867168 GO:0008013 beta-catenin binding 1/124 106/18639 0.00943396226415094 1.4180614729154 0.508135202336555 0.593601367867168 GO:0004843 cysteine-type deubiquitinase activity 1/124 108/18639 0.00925925925925926 1.39180107526882 0.514695266046654 0.597609701002498 GO:0005496 steroid binding 1/124 108/18639 0.00925925925925926 1.39180107526882 0.514695266046654 0.597609701002498 GO:0001221 transcription coregulator binding 1/124 115/18639 0.00869565217391304 1.30708274894811 0.536979408663908 0.617849801534979 GO:0017124 SH3 domain binding 1/124 115/18639 0.00869565217391304 1.30708274894811 0.536979408663908 0.617849801534979 GO:0101005 deubiquitinase activity 1/124 115/18639 0.00869565217391304 1.30708274894811 0.536979408663908 0.617849801534979 GO:0005096 GTPase activator activity 2/124 271/18639 0.00738007380073801 1.10933222235448 0.540556902385361 0.620098308442066 GO:1990782 protein tyrosine kinase binding 1/124 117/18639 0.00854700854700855 1.28473945409429 0.543157763849177 0.621216364641873 GO:0008017 microtubule binding 2/124 276/18639 0.0072463768115942 1.08923562412342 0.550467457420874 0.627697220103803 GO:0032182 ubiquitin-like protein binding 1/124 120/18639 0.00833333333333333 1.25262096774194 0.552272285206807 0.627880990919644 GO:0003697 single-stranded DNA binding 1/124 121/18639 0.00826446280991736 1.24226872833911 0.555270192039485 0.629416063380069 GO:0019783 ubiquitin-like protein peptidase activity 1/124 127/18639 0.0078740157480315 1.18357886715773 0.572844029231833 0.647415441321185 GO:0031490 chromatin DNA binding 1/124 128/18639 0.0078125 1.17433215725806 0.575705272769822 0.648668274109338 GO:0004842 ubiquitin-protein transferase activity 3/124 449/18639 0.0066815144766147 1.00432861556146 0.577348725647055 0.648668274109338 GO:0005262 calcium channel activity 1/124 131/18639 0.00763358778625954 1.14743905442009 0.584175431211038 0.654413532910899 GO:0051087 protein-folding chaperone binding 1/124 134/18639 0.00746268656716418 1.12175012036591 0.592477837196158 0.661773490669393 GO:0016779 nucleotidyltransferase activity 1/124 136/18639 0.00735294117647059 1.10525379506641 0.597921208961347 0.665906419309722 GO:0019787 ubiquitin-like protein transferase activity 3/124 479/18639 0.00626304801670146 0.941427032123375 0.621367844984169 0.688194981526749 GO:0008194 UDP-glycosyltransferase activity 1/124 145/18639 0.00689655172413793 1.03665183537264 0.62153735242599 0.688194981526749 GO:0015085 calcium ion transmembrane transporter activity 1/124 147/18639 0.00680272108843537 1.02254772876893 0.6265955659878 0.691781519330935 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/124 484/18639 0.00619834710743802 0.931701546254332 0.628398395832028 0.691781519330935 GO:0001216 DNA-binding transcription activator activity 3/124 491/18639 0.00610997963340122 0.918418632152947 0.638091658067382 0.700433946499252 GO:0003774 cytoskeletal motor activity 1/124 153/18639 0.0065359477124183 0.982447817836812 0.641371328248069 0.701865808110528 GO:0005506 iron ion binding 1/124 154/18639 0.00649350649350649 0.976068286552157 0.643776930070921 0.701865808110528 GO:0016755 aminoacyltransferase activity 3/124 496/18639 0.00604838709677419 0.909160379812695 0.644908111640825 0.701865808110528 GO:0045296 cadherin binding 2/124 334/18639 0.00598802395209581 0.900086922928337 0.654397538356352 0.710170055829905 GO:0005261 monoatomic cation channel activity 2/124 341/18639 0.00586510263929619 0.881610065272916 0.665569274408303 0.719724441743613 GO:0015081 sodium ion transmembrane transporter activity 1/124 164/18639 0.00609756097560976 0.91655192761605 0.666969770621044 0.719724441743613 GO:0061630 ubiquitin protein ligase activity 2/124 353/18639 0.0056657223796034 0.851640318011514 0.684048586224321 0.73442752972502 GO:0008201 heparin binding 1/124 172/18639 0.00581395348837209 0.87392160540135 0.684440315659967 0.73442752972502 GO:0140030 modification-dependent protein binding 1/124 173/18639 0.00578034682080925 0.868870035427932 0.686559198037081 0.734637573249761 GO:0005319 lipid transporter activity 1/124 178/18639 0.00561797752808989 0.844463573758608 0.69694376113788 0.743666247918073 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/124 181/18639 0.00552486187845304 0.830466939939405 0.703009922419343 0.748049555332003 GO:0061659 ubiquitin-like protein ligase activity 2/124 372/18639 0.00537634408602151 0.808142559833507 0.711605524594774 0.755092528875566 GO:0008234 cysteine-type peptidase activity 1/124 187/18639 0.0053475935828877 0.803820941866483 0.714783225280927 0.756363412901147 GO:0005525 GTP binding 2/124 378/18639 0.00529100529100529 0.79531490015361 0.719884125932843 0.759656729575541 GO:0015631 tubulin binding 2/124 385/18639 0.00519480519480519 0.780854629241726 0.729291238867178 0.767463507568215 GO:0016758 hexosyltransferase activity 1/124 197/18639 0.0050761421319797 0.763017848370722 0.733385233779562 0.769651536548881 GO:0019001 guanyl nucleotide binding 2/124 400/18639 0.005 0.751572580645161 0.748557856417284 0.781281697134979 GO:0032561 guanyl ribonucleotide binding 2/124 400/18639 0.005 0.751572580645161 0.748557856417284 0.781281697134979 GO:0005516 calmodulin binding 1/124 207/18639 0.00483091787439614 0.726157082748948 0.750783155561507 0.78146911559808 GO:0016887 ATP hydrolysis activity 2/124 417/18639 0.00479616306954436 0.720932931074495 0.768971448234469 0.798225796808607 GO:0005085 guanyl-nucleotide exchange factor activity 1/124 230/18639 0.00434782608695652 0.653541374474053 0.786640909719384 0.814354546105162 GO:0005216 monoatomic ion channel activity 2/124 448/18639 0.00446428571428571 0.671046947004608 0.802529710434111 0.826167654741737 GO:0005539 glycosaminoglycan binding 1/124 242/18639 0.00413223140495868 0.621134364169555 0.803266738942763 0.826167654741737 GO:0046873 metal ion transmembrane transporter activity 2/124 450/18639 0.00444444444444444 0.668064516129032 0.804540229224938 0.826167654741737 GO:0042393 histone binding 1/124 247/18639 0.00404858299595142 0.608560794044665 0.809808800253207 0.829348422779424 GO:0140104 molecular carrier activity 1/124 249/18639 0.00401606425702811 0.603672755538282 0.812364785922024 0.829741572786666 GO:0003730 mRNA 3'-UTR binding 1/124 262/18639 0.00381679389312977 0.573719527210047 0.828167919054029 0.843627053543037 GO:0016757 glycosyltransferase activity 1/124 267/18639 0.00374531835205993 0.562975715839072 0.833888065402222 0.84719478985013 GO:0030695 GTPase regulator activity 2/124 489/18639 0.00408997955010225 0.614783297051257 0.840288269908416 0.849319952641248 GO:0060589 nucleoside-triphosphatase regulator activity 2/124 490/18639 0.00408163265306122 0.613528637261356 0.841122575847874 0.849319952641248 GO:1901681 sulfur compound binding 1/124 275/18639 0.00363636363636364 0.546598240469208 0.842649900657154 0.849319952641248 GO:0005543 phospholipid binding 2/124 497/18639 0.00402414486921529 0.604887388849224 0.846853952234638 0.851311078299031 GO:0022836 gated channel activity 1/124 318/18639 0.00314465408805031 0.472687157638466 0.882457137269534 0.884773297734809 GO:0140097 catalytic activity, acting on DNA 1/124 336/18639 0.00297619047619048 0.447364631336406 0.895988178945125 0.895988178945125