category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04612 Antigen processing and presentation 4/34 82/9376 13.4519368723099 KLRC3/KLRC2/KLRC1/PSME2 6.83199701034121 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 6/34 298/9376 5.55230951440979 PRL/IL1RL1/XCL1/PRLR/XCL2/CCL3 4.81781356877293 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 5/34 238/9376 5.79337617399901 ISG15/MX1/RPL35/RPL36AL/RPL28 4.51865911611922 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 3/34 100/9376 8.27294117647059 XCL1/XCL2/CCL3 4.41097778223532 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 4/34 204/9376 5.40715109573241 LUM/ACTB/DCN/MMP9 3.83924799503769 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 4/34 232/9376 4.75456389452333 RGCC/ACTB/PFN1/CFL1 3.49333752043893 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 3/34 133/9376 6.2202565236621 KLRC3/KLRC2/KLRC1 3.65776966612794 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 3/34 142/9376 5.82601491300746 ACTB/MMP9/GSTP1 3.49577169770192 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 2/34 71/9376 7.76801988400994 PRL/PRLR 3.45332757752917 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 3/34 193/9376 4.28649801889668 XCL1/XCL2/CCL3 2.78307495059245 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 3/34 216/9376 3.83006535947712 APOA1/MMP9/CCL3 2.53852105290629 Genetic Information Processing Translation hsa03010 Ribosome 3/34 222/9376 3.72655007949126 RPL35/RPL36AL/RPL28 2.48021698530798 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 2/34 99/9376 5.57100415923945 ACTB/TPM3 2.75823078071024 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/34 233/9376 3.55061853067407 ACTB/DCN/TPM3 2.37839660602815 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 3/34 235/9376 3.52040050062578 ACTB/ATP5F1E/ATP5MG 2.36054236463379 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 2/34 105/9376 5.25266106442577 ACTB/TPM3 2.64360944734577 Human Diseases Cancer: specific types hsa05215 Prostate cancer 2/34 106/9376 5.2031076581576 MMP9/GSTP1 2.6253592800434 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 3/34 253/9376 3.26993722390142 ACTB/PFN1/SEPTIN7 2.20805778723933 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 2/34 116/9376 4.75456389452333 ACTB/MMP9 2.45464202870576 Organismal Systems Immune system hsa04611 Platelet activation 2/34 126/9376 4.37721755368814 ACTB/VAMP8 2.30238851052829 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 2/34 138/9376 3.99658994032396 ATP5F1E/ATP5MG 2.13935593733089 Organismal Systems Digestive system hsa04977 Vitamin digestion and absorption 1/34 26/9376 10.606334841629 APOA1 2.95899174982584 Genetic Information Processing Folding, sorting and degradation hsa04130 SNARE interactions in vesicular transport 1/34 33/9376 8.35650623885918 VAMP8 2.55382167356577 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 2/34 168/9376 3.28291316526611 PRL/PRLR 1.80121909950925 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 2/34 170/9376 3.24429065743945 ACTB/GSTP1 1.78144837863203 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 1/34 37/9376 7.45310015898251 APOA1 2.3725984669621 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/34 37/9376 7.45310015898251 TPM3 2.3725984669621 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/34 173/9376 3.18803128187691 ACTB/MX1 1.75233458508305 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 2/34 178/9376 3.09847984137475 LGR4/DKK1 1.70519191723813 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/34 41/9376 6.72596843615495 MMP9 2.21660792766057 Organismal Systems Digestive system hsa04975 Fat digestion and absorption 1/34 43/9376 6.41313269493844 APOA1 2.14623579330221 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 3/34 368/9376 2.24808184143223 ACTB/PFN1/ATP5F1E 1.47352649931344 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/34 45/9376 6.1281045751634 KLRC1 2.08019572916788 Genetic Information Processing Folding, sorting and degradation hsa03050 Proteasome 1/34 46/9376 5.99488491048593 PSME2 2.04865460901091 Cellular Processes Cell motility hsa04814 Motor proteins 2/34 194/9376 2.84293511218921 ACTB/TPM3 1.56475890010106 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/34 50/9376 5.51529411764706 KLRB1 1.9312055752829 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 1/34 51/9376 5.40715109573241 ACTB 1.90381074342845 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 2/34 205/9376 2.69038737446198 MMP9/ATP5F1E 1.47625026762012 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/34 52/9376 5.30316742081448 APOA1 1.87712825947756 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 2/34 212/9376 2.6015538290788 ACTB/PFN1 1.42289251747478 NA NA hsa04081 Hormone signaling 2/34 219/9376 2.51839914047811 PRL/PRLR 1.37162870342609 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 1/34 59/9376 4.67397806580259 GSTP1 1.7077711889639 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/34 70/9376 3.93949579831933 GSTP1 1.48917420500881 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/34 70/9376 3.93949579831933 ACTB 1.48917420500881 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 2/34 248/9376 2.22390891840607 ACTB/PFN1 1.17839879402137 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 1/34 72/9376 3.83006535947712 ISG15 1.45422976048043 Metabolism Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450 1/34 73/9376 3.77759871071716 GSTP1 1.43722441671385 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/34 73/9376 3.77759871071716 MX1 1.43722441671385 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 1/34 75/9376 3.67686274509804 GSTP1 1.40409689275682 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/34 76/9376 3.62848297213622 APOA1 1.38795586059867 Organismal Systems Digestive system hsa04971 Gastric acid secretion 1/34 76/9376 3.62848297213622 ACTB 1.38795586059867 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/34 78/9376 3.53544494720965 ACTB 1.35647527058173 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/34 78/9376 3.53544494720965 CFL1 1.35647527058173 Metabolism Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450 1/34 79/9376 3.49069247952345 GSTP1 1.3411192764478 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/34 82/9376 3.36298421807748 GSTP1 1.29649718585459 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 1/34 86/9376 3.20656634746922 ACTB 1.24011946509473 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 1/34 87/9376 3.16970926301555 TPM3 1.22654038748558 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/34 93/9376 2.9652118912081 ACTB 1.14897835578995 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/34 94/9376 2.93366708385482 MMP9 1.1366585274453 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/34 95/9376 2.90278637770898 CCL3 1.12450040229605 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 1/34 98/9376 2.81392557022809 CFL1 1.08895637556743 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/34 99/9376 2.78550207961973 MMP9 1.07740588795454 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 1/34 103/9376 2.67732724157624 COL14A1 1.03259840087601 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/34 103/9376 2.67732724157624 CCL3 1.03259840087601 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/34 109/9376 2.52995143011333 CCL3 0.969229170871865 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/34 110/9376 2.50695187165775 DCN 0.959079795776242 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 2/34 333/9376 1.65624447977389 ISG15/MX1 0.735591462075341 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 1/34 117/9376 2.35696329813977 ACTB 0.891013235944808 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/34 119/9376 2.3173504695996 MMP9 0.872458633623497 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/34 122/9376 2.26036644165863 ACTB 0.845312252941774 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/34 130/9376 2.12126696832579 MMP9 0.77662063415708 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/34 362/9376 1.52356191095223 PRL/PRLR 0.612870500502541 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 2/34 370/9376 1.4906200317965 PRL/PRLR 0.580878540089782 Human Diseases Infectious disease: viral hsa05162 Measles 1/34 136/9376 2.02768166089965 MX1 0.728278083011644 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/34 137/9376 2.01288106483469 ACTB 0.720462561156388 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/34 138/9376 1.99829497016198 ACTB 0.712712888368271 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/34 139/9376 1.98391874735506 MMP9 0.705027941444912 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 2/34 388/9376 1.4214675560946 ATP5F1E/DKK1 0.51150943058739 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 1/34 154/9376 1.79067990832697 TPM3 0.596834156976541 NA NA hsa04518 Integrin signaling 1/34 154/9376 1.79067990832697 ACTB 0.596834156976541 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/34 154/9376 1.79067990832697 ACTB 0.596834156976541 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/34 155/9376 1.77912713472486 ACTB 0.590052063019178 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/34 156/9376 1.76772247360483 MX1 0.583319181630171 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/34 157/9376 1.75646309479206 ACTB 0.576634774155491 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/34 163/9376 1.69180801154818 MMP9 0.537506869405836 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/34 169/9376 1.63174382178907 VAMP8 0.49995446272056 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/34 170/9376 1.62214532871972 ACTB 0.493839683129879 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/34 184/9376 1.49872122762148 CFL1 0.412161026412039 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/34 195/9376 1.41417797888386 ACTB 0.352585527326782 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/34 200/9376 1.37882352941176 ACTB 0.326685912183308 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/34 201/9376 1.37196371085748 MMP9 0.321588662357798 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/34 203/9376 1.35844682700666 ACTB 0.311474306674279 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 2/34 480/9376 1.14901960784314 ATP5F1E/DKK1 0.202195652315222 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/34 205/9376 1.34519368723099 ISG15 0.301464788991173 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/34 214/9376 1.28862012094557 CFL1 0.257657929497959 NA NA hsa04382 Cornified envelope formation 1/34 217/9376 1.27080509623204 S100A11 0.243482546734595 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/34 227/9376 1.2148224928738 CCL3 0.197656468683263 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/34 227/9376 1.2148224928738 ATP5F1E 0.197656468683263 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/34 250/9376 1.10305882352941 VAMP8 0.0996368795661827 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/34 268/9376 1.02897278314311 ATP5F1E 0.0290302828355838 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/34 275/9376 1.0027807486631 ATP5F1E 0.00282350585123292 NA NA hsa04517 IgSF CAM signaling 1/34 299/9376 0.922289986228605 ACTB -0.0823847024716698 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/34 308/9376 0.895339954163484 ATP5F1E -0.112669323936253 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/34 323/9376 0.85376069932617 MMP9 -0.16135196835648 NA NA hsa04519 Cadherin signaling 1/34 404/9376 0.682585905649388 ACTB -0.393439013504302