ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0060589	nucleoside-triphosphatase regulator activity	154/3237	490/18639	0.314285714285714	1.80969151330597	1.00223107600965e-14	1.2383517718896e-11
GO:0030695	GTPase regulator activity	153/3237	489/18639	0.312883435582822	1.80161703918079	1.8635843068316e-14	1.2383517718896e-11
GO:0005096	GTPase activator activity	86/3237	271/18639	0.317343173431734	1.82729669743407	4.72462965744906e-09	2.09301093824994e-06
GO:0005085	guanyl-nucleotide exchange factor activity	75/3237	230/18639	0.326086956521739	1.87764435669098	1.23203122718909e-08	4.09342375233574e-06
GO:0004674	protein serine/threonine kinase activity	116/3237	433/18639	0.267898383371824	1.54258818896121	4.84988059230958e-07	0.000128909826143589
GO:0031267	small GTPase binding	79/3237	283/18639	0.279151943462898	1.60738741866078	6.15005664086333e-06	0.00136223754595123
GO:0023026	MHC class II protein complex binding	15/3237	27/18639	0.555555555555556	3.19894964473278	8.05871134160705e-06	0.00153000391042797
GO:0019787	ubiquitin-like protein transferase activity	120/3237	479/18639	0.250521920668058	1.44253261641395	1.11175958755169e-05	0.00184691061482025
GO:0044389	ubiquitin-like protein ligase binding	86/3237	322/18639	0.267080745341615	1.53788013976594	1.58804084477823e-05	0.00234500698078919
GO:0035497	cAMP response element binding	9/3237	12/18639	0.75	4.31858202038925	1.88567431907832e-05	0.00238344987351714
GO:0106310	protein serine kinase activity	94/3237	361/18639	0.260387811634349	1.4993414955368	1.97275760787724e-05	0.00238344987351714
GO:0042605	peptide antigen binding	20/3237	45/18639	0.444444444444444	2.55915971578622	2.15832610850037e-05	0.00239034616516416
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	18/3237	39/18639	0.461538461538462	2.65758893562415	2.96289201361904e-05	0.00302898729699977
GO:0016755	aminoacyltransferase activity	121/3237	496/18639	0.243951612903226	1.40470006577177	3.73781013817697e-05	0.00354824976688371
GO:0023023	MHC protein complex binding	17/3237	37/18639	0.459459459459459	2.64561781429251	5.28574327322315e-05	0.00468316854007571
GO:0008017	microtubule binding	73/3237	276/18639	0.264492753623188	1.52297820042713	9.37197962731172e-05	0.00760795169108276
GO:0015631	tubulin binding	96/3237	385/18639	0.249350649350649	1.43578830807746	9.73176664773566e-05	0.00760795169108276
GO:0004842	ubiquitin-protein transferase activity	109/3237	449/18639	0.242761692650334	1.39784837482532	0.000109233666325731	0.00788337420207819
GO:0051020	GTPase binding	81/3237	315/18639	0.257142857142857	1.48065669270489	0.000112704371587273	0.00788337420207819
GO:0016798	hydrolase activity, acting on glycosyl bonds	40/3237	130/18639	0.307692307692308	1.77172595708277	0.000124206404784682	0.00825351559794211
GO:0043539	protein serine/threonine kinase activator activity	26/3237	73/18639	0.356164383561644	2.05083347086978	0.000140458100932093	0.00888899124470246
GO:0000287	magnesium ion binding	62/3237	230/18639	0.269565217391304	1.55218600153121	0.000172748003328414	0.0104355498374301
GO:0019887	protein kinase regulator activity	67/3237	255/18639	0.262745098039216	1.51291500845009	0.000218430942250817	0.0120994020393484
GO:0031625	ubiquitin protein ligase binding	77/3237	302/18639	0.254966887417219	1.46812722105948	0.000218499359627059	0.0120994020393484
GO:0140297	DNA-binding transcription factor binding	115/3237	488/18639	0.235655737704918	1.3569315091387	0.000256220422185306	0.0136206776433709
GO:0032395	MHC class II receptor activity	7/3237	10/18639	0.7	4.0306765523633	0.000347708651027067	0.0177732614313451
GO:0032182	ubiquitin-like protein binding	36/3237	120/18639	0.3	1.7274328081557	0.000453476267209494	0.0221958650586144
GO:0061659	ubiquitin-like protein ligase activity	90/3237	372/18639	0.241935483870968	1.39309097431911	0.000467632973394434	0.0221958650586144
GO:0019207	kinase regulator activity	72/3237	287/18639	0.250871080139373	1.44454311483403	0.000565588086489644	0.0259195367911978
GO:0004518	nuclease activity	55/3237	209/18639	0.263157894736842	1.51529193697868	0.00073154896696406	0.0324076192365079
GO:0004540	RNA nuclease activity	35/3237	121/18639	0.289256198347107	1.66556882329062	0.00111639084465248	0.0478607558884885
GO:0005543	phospholipid binding	113/3237	497/18639	0.227364185110664	1.30918784253249	0.00115519825702826	0.0479768276122051
GO:0000217	DNA secondary structure binding	15/3237	39/18639	0.384615384615385	2.21465744635346	0.00144354442827477	0.0580826466677598
GO:0004706	JUN kinase kinase kinase activity	9/3237	18/18639	0.5	2.8790546802595	0.00152493892032024	0.0580826466677598
GO:0004712	protein serine/threonine/tyrosine kinase activity	16/3237	43/18639	0.372093023255814	2.14255232019312	0.00152964080765357	0.0580826466677598
GO:0140313	molecular sequestering activity	19/3237	55/18639	0.345454545454545	1.98916505181565	0.00162050760954752	0.0598237392524625
GO:0140098	catalytic activity, acting on RNA	90/3237	387/18639	0.232558139534884	1.3390952001207	0.00173139122390403	0.0606879735821785
GO:0017025	TBP-class protein binding	11/3237	25/18639	0.44	2.53356811862836	0.00173524679918945	0.0606879735821785
GO:0140375	immune receptor activity	42/3237	156/18639	0.269230769230769	1.55026021244742	0.00182731249561544	0.0622691873505876
GO:0061133	endopeptidase activator activity	10/3237	22/18639	0.454545454545455	2.61732243659954	0.00208300922252823	0.0692079814185005
GO:0140296	general transcription initiation factor binding	18/3237	53/18639	0.339622641509434	1.95558431111966	0.0026373468506945	0.084774392328053
GO:0043130	ubiquitin binding	29/3237	100/18639	0.29	1.66985171455051	0.00272570248176536	0.084774392328053
GO:0061630	ubiquitin protein ligase activity	82/3237	353/18639	0.232294617563739	1.33757781179195	0.00278254418811841	0.084774392328053
GO:0015923	mannosidase activity	8/3237	16/18639	0.5	2.8790546802595	0.002806676645925	0.084774392328053
GO:0005338	nucleotide-sugar transmembrane transporter activity	7/3237	13/18639	0.538461538461538	3.10052042489485	0.00305453580079155	0.0902106239833772
GO:0005164	tumor necrosis factor receptor binding	12/3237	31/18639	0.387096774193548	2.22894555891058	0.0039776475253248	0.106093389394468
GO:0043021	ribonucleoprotein complex binding	45/3237	177/18639	0.254237288135593	1.46392610860653	0.00427849132494922	0.106093389394468
GO:0035091	phosphatidylinositol binding	67/3237	284/18639	0.235915492957746	1.35842720829145	0.0043822185678543	0.106093389394468
GO:0004659	prenyltransferase activity	8/3237	17/18639	0.470588235294118	2.70969852259718	0.00450090635542941	0.106093389394468
GO:0017110	nucleoside diphosphate phosphatase activity	8/3237	17/18639	0.470588235294118	2.70969852259718	0.00450090635542941	0.106093389394468
GO:0019208	phosphatase regulator activity	32/3237	117/18639	0.273504273504274	1.57486751740691	0.00462996949721024	0.106093389394468
GO:0035173	histone kinase activity	82/3237	360/18639	0.227777777777778	1.31156935434044	0.00482307830329886	0.106093389394468
GO:0004677	DNA-dependent protein kinase activity	59/3237	246/18639	0.239837398373984	1.38100996857976	0.00494463189236277	0.106093389394468
GO:0140857	histone H3T45 kinase activity	59/3237	246/18639	0.239837398373984	1.38100996857976	0.00494463189236277	0.106093389394468
GO:0016779	nucleotidyltransferase activity	36/3237	136/18639	0.264705882352941	1.52420541896091	0.00499557107128512	0.106093389394468
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	7/3237	14/18639	0.5	2.8790546802595	0.00519914785180554	0.106093389394468
GO:0032266	phosphatidylinositol-3-phosphate binding	16/3237	48/18639	0.333333333333333	1.91936978683967	0.00548031846625645	0.106093389394468
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	9/3237	21/18639	0.428571428571429	2.46776115450814	0.00560739656999587	0.106093389394468
GO:0051010	microtubule plus-end binding	9/3237	21/18639	0.428571428571429	2.46776115450814	0.00560739656999587	0.106093389394468
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	14/3237	40/18639	0.35	2.01533827618165	0.00561202549867341	0.106093389394468
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/3237	11/18639	0.545454545454545	3.14078692391945	0.00568456327638619	0.106093389394468
GO:0042608	T cell receptor binding	6/3237	11/18639	0.545454545454545	3.14078692391945	0.00568456327638619	0.106093389394468
GO:0140031	phosphorylation-dependent protein binding	6/3237	11/18639	0.545454545454545	3.14078692391945	0.00568456327638619	0.106093389394468
GO:0004679	AMP-activated protein kinase activity	59/3237	248/18639	0.237903225806452	1.36987279141379	0.00593471102740849	0.106093389394468
GO:1901981	phosphatidylinositol phosphate binding	46/3237	185/18639	0.248648648648649	1.43174611126418	0.00607438609010482	0.106093389394468
GO:0052689	carboxylic ester hydrolase activity	26/3237	92/18639	0.282608695652174	1.62729177579885	0.00636595054582291	0.106093389394468
GO:0004709	MAP kinase kinase kinase activity	10/3237	25/18639	0.4	2.3032437442076	0.0063792204546974	0.106093389394468
GO:0141003	histone H2AX kinase activity	80/3237	354/18639	0.225988700564972	1.30126765209469	0.00654459705570633	0.106093389394468
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	79/3237	349/18639	0.226361031518625	1.30341157444413	0.00656901732772447	0.106093389394468
GO:0001221	transcription coregulator binding	31/3237	115/18639	0.269565217391304	1.55218600153121	0.00660452196508335	0.106093389394468
GO:0004676	3-phosphoinositide-dependent protein kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0004711	ribosomal protein S6 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0035175	histone H3S10 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0035979	histone H2AXS139 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0044022	histone H3S28 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0044023	histone H4S1 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0044024	histone H2AS1 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0044025	histone H2BS14 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0072354	histone H3T3 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0072371	histone H2AS121 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0072518	Rho-dependent protein serine/threonine kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0140823	histone H2BS36 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0140855	histone H3S57 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0140995	histone H2A kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0140997	histone H4 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0140998	histone H2B kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:1990244	histone H2AT120 kinase activity	58/3237	245/18639	0.236734693877551	1.36314425677593	0.00704826594952735	0.106093389394468
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	12/3237	33/18639	0.363636363636364	2.09385794927964	0.00713164840358666	0.106093389394468
GO:0140311	protein sequestering activity	12/3237	33/18639	0.363636363636364	2.09385794927964	0.00713164840358666	0.106093389394468
GO:0042169	SH2 domain binding	14/3237	41/18639	0.341463414634146	1.96618368407966	0.00718465390933191	0.106093389394468
GO:0140030	modification-dependent protein binding	43/3237	173/18639	0.248554913294798	1.43120637284576	0.00783425385709309	0.11441454259425
GO:0140035	ubiquitin-like protein reader activity	9/3237	22/18639	0.409090909090909	2.35559019293959	0.00804735704131962	0.116231869417427
GO:0140996	histone H3 kinase activity	80/3237	357/18639	0.224089635854342	1.29033262980818	0.00813493668537458	0.116231869417427
GO:0004559	alpha-mannosidase activity	7/3237	15/18639	0.466666666666667	2.68711770157553	0.00830135077365149	0.116231869417427
GO:0035402	histone H3T11 kinase activity	58/3237	247/18639	0.234817813765182	1.3521066514579	0.00839598153805345	0.116231869417427
GO:0035403	histone H3T6 kinase activity	58/3237	247/18639	0.234817813765182	1.3521066514579	0.00839598153805345	0.116231869417427
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	57/3237	243/18639	0.234567901234568	1.35066762777606	0.00911528574465091	0.123124460924895
GO:0001968	fibronectin binding	11/3237	30/18639	0.366666666666667	2.11130676552363	0.00917179957228341	0.123124460924895
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/3237	30/18639	0.366666666666667	2.11130676552363	0.00917179957228341	0.123124460924895
GO:0008175	tRNA methyltransferase activity	12/3237	34/18639	0.352941176470588	2.03227389194788	0.00931187166965388	0.1237547744897
GO:0035259	nuclear glucocorticoid receptor binding	6/3237	12/18639	0.5	2.8790546802595	0.00971165096959633	0.126537099397976
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	6/3237	12/18639	0.5	2.8790546802595	0.00971165096959633	0.126537099397976
GO:0008574	plus-end-directed microtubule motor activity	8/3237	19/18639	0.421052631578947	2.42446709916589	0.0101019336194762	0.130344366798872
GO:0004521	RNA endonuclease activity	21/3237	73/18639	0.287671232876712	1.65644241877944	0.0108104893626972	0.138145580413698
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	18/3237	60/18639	0.3	1.7274328081557	0.0112163514891811	0.141966963134493
GO:0004683	calcium/calmodulin-dependent protein kinase activity	10/3237	27/18639	0.37037037037037	2.13263309648852	0.011811834354085	0.146709606136251
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	10/3237	27/18639	0.37037037037037	2.13263309648852	0.011811834354085	0.146709606136251
GO:0043015	gamma-tubulin binding	12/3237	35/18639	0.342857142857143	1.97420892360651	0.0119761445983707	0.146926927113538
GO:0017124	SH3 domain binding	30/3237	115/18639	0.260869565217391	1.50211548535278	0.0120504402222541	0.146926927113538
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	7/3237	16/18639	0.4375	2.51917284522706	0.0125749862063277	0.150499380892619
GO:0001540	amyloid-beta binding	23/3237	83/18639	0.27710843373494	1.59562066616792	0.0126237694310425	0.150499380892619
GO:0003678	DNA helicase activity	21/3237	74/18639	0.283783783783784	1.63405806176891	0.0126831682919287	0.150499380892619
GO:0038187	pattern recognition receptor activity	15/3237	48/18639	0.3125	1.79940917516219	0.0133856790666386	0.156756536905655
GO:0004197	cysteine-type endopeptidase activity	24/3237	88/18639	0.272727272727273	1.57039346195973	0.0134463846555641	0.156756536905655
GO:0001217	DNA-binding transcription repressor activity	63/3237	278/18639	0.226618705035971	1.30489528673632	0.0136355274961473	0.157579269933737
GO:0003697	single-stranded DNA binding	31/3237	121/18639	0.256198347107438	1.47521810062883	0.0140793253616479	0.161242248704774
GO:0001614	purinergic nucleotide receptor activity	8/3237	20/18639	0.4	2.3032437442076	0.0143164675298445	0.161242248704774
GO:0016502	nucleotide receptor activity	8/3237	20/18639	0.4	2.3032437442076	0.0143164675298445	0.161242248704774
GO:0004527	exonuclease activity	23/3237	84/18639	0.273809523809524	1.57662518204687	0.0145983530750064	0.161676760305696
GO:0004860	protein kinase inhibitor activity	23/3237	84/18639	0.273809523809524	1.57662518204687	0.0145983530750064	0.161676760305696
GO:0043022	ribosome binding	29/3237	112/18639	0.258928571428571	1.49093903084867	0.0148480893011203	0.162620550256467
GO:0042277	peptide binding	57/3237	249/18639	0.228915662650602	1.31812141987784	0.0149599065955831	0.162620550256467
GO:0005484	SNAP receptor activity	12/3237	36/18639	0.333333333333333	1.91936978683967	0.0151880095825492	0.162620550256467
GO:0004622	lysophospholipase activity	9/3237	24/18639	0.375	2.15929101019462	0.0152338453168164	0.162620550256467
GO:0035325	Toll-like receptor binding	6/3237	13/18639	0.461538461538462	2.65758893562415	0.0154177496857147	0.162620550256467
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	6/3237	13/18639	0.461538461538462	2.65758893562415	0.0154177496857147	0.162620550256467
GO:0005126	cytokine receptor binding	62/3237	275/18639	0.225454545454545	1.29819192855337	0.0159063636785612	0.166453207313448
GO:0004519	endonuclease activity	32/3237	127/18639	0.251968503937008	1.45086220107565	0.0162420390725166	0.168638046307614
GO:0005525	GTP binding	82/3237	378/18639	0.216931216931217	1.24911367080042	0.0167040767017962	0.172090836718505
GO:0008408	3'-5' exonuclease activity	17/3237	58/18639	0.293103448275862	1.68772170911764	0.0170719740326607	0.172910240551018
GO:0051536	iron-sulfur cluster binding	21/3237	76/18639	0.276315789473684	1.59105653382762	0.0171969024958337	0.172910240551018
GO:0004715	non-membrane spanning protein tyrosine kinase activity	14/3237	45/18639	0.311111111111111	1.79141180105036	0.0172372663293768	0.172910240551018
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	13/3237	41/18639	0.317073170731707	1.82574199235968	0.0181664160766578	0.172910240551018
GO:0017080	sodium channel regulator activity	13/3237	41/18639	0.317073170731707	1.82574199235968	0.0181664160766578	0.172910240551018
GO:0005092	GDP-dissociation inhibitor activity	7/3237	17/18639	0.411764705882353	2.37098620727253	0.0182268421019564	0.172910240551018
GO:0032183	SUMO binding	7/3237	17/18639	0.411764705882353	2.37098620727253	0.0182268421019564	0.172910240551018
GO:0032977	membrane insertase activity	7/3237	17/18639	0.411764705882353	2.37098620727253	0.0182268421019564	0.172910240551018
GO:0003925	G protein activity	16/3237	54/18639	0.296296296296296	1.70610647719081	0.0183169803373002	0.172910240551018
GO:0004382	GDP phosphatase activity	5/3237	10/18639	0.5	2.8790546802595	0.0183448787943517	0.172910240551018
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	5/3237	10/18639	0.5	2.8790546802595	0.0183448787943517	0.172910240551018
GO:1905394	retromer complex binding	5/3237	10/18639	0.5	2.8790546802595	0.0183448787943517	0.172910240551018
GO:0005518	collagen binding	20/3237	72/18639	0.277777777777778	1.59947482236639	0.0186571273901539	0.174614945785314
GO:0051540	metal cluster binding	21/3237	77/18639	0.272727272727273	1.57039346195973	0.0198808011639581	0.18292789322571
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	60/3237	268/18639	0.223880597014925	1.28912896131022	0.0200344771196192	0.18292789322571
GO:0031593	polyubiquitin modification-dependent protein binding	17/3237	59/18639	0.288135593220339	1.65911625642073	0.0202047985466745	0.18292789322571
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	9/3237	25/18639	0.36	2.07291936978684	0.0202145718017584	0.18292789322571
GO:0032934	sterol binding	19/3237	68/18639	0.279411764705882	1.60888349779207	0.020233559295846	0.18292789322571
GO:0140597	protein carrier chaperone	44/3237	188/18639	0.234042553191489	1.34764261629168	0.0206956838450164	0.185841647500181
GO:0030295	protein kinase activator activity	34/3237	139/18639	0.244604316546763	1.40845840473127	0.0209317030440023	0.186699552654222
GO:0140097	catalytic activity, acting on DNA	73/3237	336/18639	0.217261904761905	1.25101780749371	0.0220918089062548	0.195733426909418
GO:0008474	palmitoyl-(protein) hydrolase activity	6/3237	14/18639	0.428571428571429	2.46776115450814	0.0230817010611466	0.201813030988578
GO:0098599	palmitoyl hydrolase activity	6/3237	14/18639	0.428571428571429	2.46776115450814	0.0230817010611466	0.201813030988578
GO:0043531	ADP binding	12/3237	38/18639	0.315789473684211	1.81835032437442	0.0235088546115005	0.203845150849736
GO:0009055	electron transfer activity	29/3237	116/18639	0.25	1.43952734012975	0.0236208827922192	0.203845150849736
GO:0003684	damaged DNA binding	20/3237	74/18639	0.27027027027027	1.55624577311324	0.0249273653093555	0.212218805853714
GO:0019888	protein phosphatase regulator activity	27/3237	107/18639	0.252336448598131	1.45298086667302	0.0252065262778228	0.212218805853714
GO:0000900	mRNA regulatory element binding translation repressor activity	7/3237	18/18639	0.388888888888889	2.23926475131294	0.0254464905191454	0.212218805853714
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	7/3237	18/18639	0.388888888888889	2.23926475131294	0.0254464905191454	0.212218805853714
GO:0030228	lipoprotein particle receptor activity	7/3237	18/18639	0.388888888888889	2.23926475131294	0.0254464905191454	0.212218805853714
GO:0038024	cargo receptor activity	18/3237	65/18639	0.276923076923077	1.59455336137449	0.0255492919011244	0.212218805853714
GO:0004529	DNA exonuclease activity	9/3237	26/18639	0.346153846153846	1.99319170171811	0.0262689535208722	0.214070961498055
GO:0005160	transforming growth factor beta receptor binding	9/3237	26/18639	0.346153846153846	1.99319170171811	0.0262689535208722	0.214070961498055
GO:0070034	telomerase RNA binding	8/3237	22/18639	0.363636363636364	2.09385794927964	0.0263207751108332	0.214070961498055
GO:0016887	ATP hydrolysis activity	88/3237	417/18639	0.211031175059952	1.21514058447403	0.0264165821562687	0.214070961498055
GO:0003725	double-stranded RNA binding	20/3237	75/18639	0.266666666666667	1.53549582947173	0.0286082689809459	0.22554685406126
GO:0005114	type II transforming growth factor beta receptor binding	5/3237	11/18639	0.454545454545455	2.61732243659954	0.0288951417259897	0.22554685406126
GO:0005225	volume-sensitive anion channel activity	5/3237	11/18639	0.454545454545455	2.61732243659954	0.0288951417259897	0.22554685406126
GO:0010854	adenylate cyclase regulator activity	5/3237	11/18639	0.454545454545455	2.61732243659954	0.0288951417259897	0.22554685406126
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/3237	11/18639	0.454545454545455	2.61732243659954	0.0288951417259897	0.22554685406126
GO:0032794	GTPase activating protein binding	5/3237	11/18639	0.454545454545455	2.61732243659954	0.0288951417259897	0.22554685406126
GO:0008234	cysteine-type peptidase activity	43/3237	187/18639	0.229946524064171	1.32405723263271	0.0290207013126227	0.22554685406126
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	14/3237	48/18639	0.291666666666667	1.67944856348471	0.0300167161531044	0.23035115594894
GO:0140693	molecular condensate scaffold activity	14/3237	48/18639	0.291666666666667	1.67944856348471	0.0300167161531044	0.23035115594894
GO:0016504	peptidase activator activity	16/3237	57/18639	0.280701754385965	1.61631139944393	0.0301588420881231	0.23035115594894
GO:0019209	kinase activator activity	35/3237	148/18639	0.236486486486486	1.36171505147409	0.0311744435129188	0.236747631020966
GO:0140104	molecular carrier activity	55/3237	249/18639	0.220883534136546	1.27187154549616	0.0317815460916719	0.239986788385409
GO:0019210	kinase inhibitor activity	23/3237	90/18639	0.255555555555556	1.47151683657708	0.0320674744738169	0.24077781681188
GO:0001046	core promoter sequence-specific DNA binding	13/3237	44/18639	0.295454545454545	1.7012595837897	0.0323455335483963	0.241501202729318
GO:1901505	carbohydrate derivative transmembrane transporter activity	15/3237	53/18639	0.283018867924528	1.62965359259972	0.0327409917656798	0.243088145567533
GO:0005041	low-density lipoprotein particle receptor activity	6/3237	15/18639	0.4	2.3032437442076	0.0329352679194766	0.243172061472135
GO:0003887	DNA-directed DNA polymerase activity	8/3237	23/18639	0.347826086956522	2.00282064713704	0.0343762471991732	0.251022156745611
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	8/3237	23/18639	0.347826086956522	2.00282064713704	0.0343762471991732	0.251022156745611
GO:0016763	pentosyltransferase activity	14/3237	49/18639	0.285714285714286	1.64517410300543	0.0355158453649769	0.25792654912598
GO:0016741	transferase activity, transferring one-carbon groups	48/3237	215/18639	0.223255813953488	1.28553139211587	0.035928473081248	0.259505112635753
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	31/3237	130/18639	0.238461538461538	1.37308761673915	0.0366570171982969	0.263336085711008
GO:0019902	phosphatase binding	43/3237	190/18639	0.226315789473684	1.30315106580167	0.0369128500767804	0.263748267484092
GO:0055106	ubiquitin-protein transferase regulator activity	11/3237	36/18639	0.305555555555556	1.75942230460303	0.0372353022069892	0.264318126485787
GO:0004386	helicase activity	36/3237	155/18639	0.232258064516129	1.33736733534635	0.0373903745517893	0.264318126485787
GO:0000149	SNARE binding	26/3237	106/18639	0.245283018867925	1.41236644691975	0.0383385840058256	0.269180326231776
GO:0051539	4 iron, 4 sulfur cluster binding	13/3237	45/18639	0.288888888888889	1.66345381526104	0.0384832671061229	0.269180326231776
GO:0003777	microtubule motor activity	18/3237	68/18639	0.264705882352941	1.52420541896091	0.0391016651583709	0.272073890028665
GO:0002020	protease binding	32/3237	136/18639	0.235294117647059	1.35484926129859	0.0404775119815876	0.276157351604959
GO:0005178	integrin binding	37/3237	161/18639	0.229813664596273	1.32329221328697	0.0407031225016244	0.276157351604959
GO:0001530	lipopolysaccharide binding	12/3237	41/18639	0.292682926829268	1.68530030063971	0.0416343332141729	0.276157351604959
GO:0061650	ubiquitin-like protein conjugating enzyme activity	12/3237	41/18639	0.292682926829268	1.68530030063971	0.0416343332141729	0.276157351604959
GO:0015605	organophosphate ester transmembrane transporter activity	14/3237	50/18639	0.28	1.61227062094532	0.0417030888222469	0.276157351604959
GO:0032813	tumor necrosis factor receptor superfamily binding	14/3237	50/18639	0.28	1.61227062094532	0.0417030888222469	0.276157351604959
GO:0046875	ephrin receptor binding	9/3237	28/18639	0.321428571428571	1.85082086588111	0.0419881086935151	0.276157351604959
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	9/3237	28/18639	0.321428571428571	1.85082086588111	0.0419881086935151	0.276157351604959
GO:0000995	RNA polymerase III general transcription initiation factor activity	5/3237	12/18639	0.416666666666667	2.39921223354958	0.0425976351234135	0.276157351604959
GO:0004875	complement receptor activity	5/3237	12/18639	0.416666666666667	2.39921223354958	0.0425976351234135	0.276157351604959
GO:0005095	GTPase inhibitor activity	5/3237	12/18639	0.416666666666667	2.39921223354958	0.0425976351234135	0.276157351604959
GO:0008603	cAMP-dependent protein kinase regulator activity	5/3237	12/18639	0.416666666666667	2.39921223354958	0.0425976351234135	0.276157351604959
GO:0016423	tRNA (guanine) methyltransferase activity	5/3237	12/18639	0.416666666666667	2.39921223354958	0.0425976351234135	0.276157351604959
GO:0097677	STAT family protein binding	5/3237	12/18639	0.416666666666667	2.39921223354958	0.0425976351234135	0.276157351604959
GO:0019001	guanyl nucleotide binding	83/3237	400/18639	0.2075	1.19480769230769	0.0433111996448158	0.278070455690629
GO:0032561	guanyl ribonucleotide binding	83/3237	400/18639	0.2075	1.19480769230769	0.0433111996448158	0.278070455690629
GO:0004857	enzyme inhibitor activity	86/3237	416/18639	0.206730769230769	1.19037837741499	0.0436246817950362	0.27873654858463
GO:0030215	semaphorin receptor binding	8/3237	24/18639	0.333333333333333	1.91936978683967	0.0439474481403515	0.279455304203479
GO:0043394	proteoglycan binding	11/3237	37/18639	0.297297297297297	1.71187035042457	0.0449454593891354	0.282087026109827
GO:0004708	MAP kinase kinase activity	6/3237	16/18639	0.375	2.15929101019462	0.045151436947366	0.282087026109827
GO:0097027	ubiquitin-protein transferase activator activity	6/3237	16/18639	0.375	2.15929101019462	0.045151436947366	0.282087026109827
GO:0043024	ribosomal small subunit binding	7/3237	20/18639	0.35	2.01533827618165	0.0452103360130874	0.282087026109827
GO:0005496	steroid binding	26/3237	108/18639	0.240740740740741	1.38621151271754	0.0471011359887972	0.292511260416409
GO:0046332	SMAD binding	20/3237	79/18639	0.253164556962025	1.45774920519468	0.0474945657410019	0.293582687766472
GO:0022853	active monoatomic ion transmembrane transporter activity	28/3237	118/18639	0.23728813559322	1.36633103469942	0.0478349835769174	0.294318023952422
GO:0140416	transcription regulator inhibitor activity	10/3237	33/18639	0.303030303030303	1.7448816243997	0.0483684696515569	0.296229014594097
GO:0051117	ATPase binding	21/3237	84/18639	0.25	1.43952734012975	0.0486269280965674	0.296445813946505
GO:0008168	methyltransferase activity	45/3237	204/18639	0.220588235294118	1.27017118246743	0.0490505508044449	0.297662931594097
GO:0019894	kinesin binding	12/3237	42/18639	0.285714285714286	1.64517410300543	0.049393711430218	0.298382920412544
GO:0097110	scaffold protein binding	18/3237	70/18639	0.257142857142857	1.48065669270489	0.0506452272777414	0.304558855439449
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	9/3237	29/18639	0.310344827586207	1.78699945671279	0.0518132209781421	0.310179147206986
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	16/3237	61/18639	0.262295081967213	1.51032376669351	0.0536563077354417	0.319772345203596
GO:0003707	nuclear steroid receptor activity	8/3237	25/18639	0.32	1.84259499536608	0.0551158605349837	0.327004368977649
GO:0003924	GTPase activity	69/3237	331/18639	0.208459214501511	1.20033095430759	0.0558461509057714	0.329864598016756
GO:0004713	protein tyrosine kinase activity	32/3237	140/18639	0.228571428571429	1.31613928240434	0.0574058942385535	0.336472367137404
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	7/3237	21/18639	0.333333333333333	1.91936978683967	0.057977556113217	0.336472367137404
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/3237	21/18639	0.333333333333333	1.91936978683967	0.057977556113217	0.336472367137404
GO:0008373	sialyltransferase activity	7/3237	21/18639	0.333333333333333	1.91936978683967	0.057977556113217	0.336472367137404
GO:0015932	nucleobase-containing compound transmembrane transporter activity	15/3237	57/18639	0.263157894736842	1.51529193697868	0.0589111913780172	0.336966708794623
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	5/3237	13/18639	0.384615384615385	2.21465744635346	0.0595850635219752	0.336966708794623
GO:0004535	poly(A)-specific ribonuclease activity	5/3237	13/18639	0.384615384615385	2.21465744635346	0.0595850635219752	0.336966708794623
GO:0035673	oligopeptide transmembrane transporter activity	5/3237	13/18639	0.384615384615385	2.21465744635346	0.0595850635219752	0.336966708794623
GO:0140852	histone ubiquitin ligase activity	5/3237	13/18639	0.384615384615385	2.21465744635346	0.0595850635219752	0.336966708794623
GO:0001618	virus receptor activity	20/3237	81/18639	0.246913580246914	1.42175539765901	0.0597178028476775	0.336966708794623
GO:0070402	NADPH binding	6/3237	17/18639	0.352941176470588	2.03227389194788	0.0598375795903168	0.336966708794623
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	22/3237	91/18639	0.241758241758242	1.39207039485075	0.0613589229014056	0.344075985383832
GO:0036121	double-stranded DNA helicase activity	13/3237	48/18639	0.270833333333333	1.55948795180723	0.0617271104390605	0.344686259552569
GO:0008173	RNA methyltransferase activity	17/3237	67/18639	0.253731343283582	1.46101282281825	0.0629139454909737	0.349843655052318
GO:0016251	RNA polymerase II general transcription initiation factor activity	14/3237	53/18639	0.264150943396226	1.52101001975974	0.0647327667970486	0.358457696138657
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	37/3237	167/18639	0.221556886227545	1.27574878047427	0.065191532868295	0.359500195775785
GO:0140272	exogenous protein binding	20/3237	82/18639	0.24390243902439	1.40441691719976	0.0665847166446279	0.365665654631035
GO:0017116	single-stranded DNA helicase activity	15/3237	58/18639	0.258620689655172	1.48916621392733	0.0672019619867228	0.36702392301082
GO:0016790	thiolester hydrolase activity	12/3237	44/18639	0.272727272727273	1.57039346195973	0.0677350391316297	0.36702392301082
GO:0043178	alcohol binding	22/3237	92/18639	0.239130434782609	1.37693919490672	0.0679252251207036	0.36702392301082
GO:0008198	ferrous iron binding	8/3237	26/18639	0.307692307692308	1.77172595708277	0.0679367080968109	0.36702392301082
GO:0008238	exopeptidase activity	24/3237	102/18639	0.235294117647059	1.35484926129859	0.0686287797673364	0.369261734051782
GO:0061631	ubiquitin conjugating enzyme activity	10/3237	35/18639	0.285714285714286	1.64517410300543	0.0693362680640473	0.371564113939996
GO:0140223	general transcription initiation factor activity	17/3237	68/18639	0.25	1.43952734012975	0.0708513722685078	0.378158529095771
GO:0001222	transcription corepressor binding	13/3237	49/18639	0.26530612244898	1.52766166707647	0.0711922894935906	0.378458210947928
GO:0008093	cytoskeletal anchor activity	7/3237	22/18639	0.318181818181818	1.83212570561968	0.0727507205809961	0.381061739984268
GO:0033691	sialic acid binding	7/3237	22/18639	0.318181818181818	1.83212570561968	0.0727507205809961	0.381061739984268
GO:0015485	cholesterol binding	14/3237	54/18639	0.259259259259259	1.49284316754196	0.0739881942118995	0.381061739984268
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	14/3237	54/18639	0.259259259259259	1.49284316754196	0.0739881942118995	0.381061739984268
GO:0050661	NADP binding	14/3237	54/18639	0.259259259259259	1.49284316754196	0.0739881942118995	0.381061739984268
GO:0051287	NAD binding	14/3237	54/18639	0.259259259259259	1.49284316754196	0.0739881942118995	0.381061739984268
GO:0051219	phosphoprotein binding	22/3237	93/18639	0.236559139784946	1.36213339711202	0.0749587897893888	0.381061739984268
GO:0140713	histone chaperone activity	36/3237	164/18639	0.219512195121951	1.26397522547978	0.0760760408354771	0.381061739984268
GO:0045309	protein phosphorylated amino acid binding	15/3237	59/18639	0.254237288135593	1.46392610860653	0.0762356288986568	0.381061739984268
GO:0000400	four-way junction DNA binding	6/3237	18/18639	0.333333333333333	1.91936978683967	0.0770331241259025	0.381061739984268
GO:0016854	racemase and epimerase activity	6/3237	18/18639	0.333333333333333	1.91936978683967	0.0770331241259025	0.381061739984268
GO:0032393	MHC class I receptor activity	6/3237	18/18639	0.333333333333333	1.91936978683967	0.0770331241259025	0.381061739984268
GO:0004536	DNA nuclease activity	16/3237	64/18639	0.25	1.43952734012975	0.078025481918592	0.381061739984268
GO:0003680	minor groove of adenine-thymine-rich DNA binding	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0004090	carbonyl reductase (NADPH) activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0005528	FK506 binding	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0008140	cAMP response element binding protein binding	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0008239	dipeptidyl-peptidase activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0015658	branched-chain amino acid transmembrane transporter activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0016427	tRNA (cytidine) methyltransferase activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0031434	mitogen-activated protein kinase kinase binding	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0043422	protein kinase B binding	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0050308	sugar-phosphatase activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:1990757	ubiquitin ligase activator activity	4/3237	10/18639	0.4	2.3032437442076	0.07913697534662	0.381061739984268
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/3237	14/18639	0.357142857142857	2.05646762875679	0.0798647093335466	0.381799275914689
GO:0061665	SUMO ligase activity	5/3237	14/18639	0.357142857142857	2.05646762875679	0.0798647093335466	0.381799275914689
GO:0044390	ubiquitin-like protein conjugating enzyme binding	10/3237	36/18639	0.277777777777778	1.59947482236639	0.0816827933936849	0.389091155627983
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	15/3237	60/18639	0.25	1.43952734012975	0.0860258505582373	0.408315554971062
GO:0035401	histone H3Y41 kinase activity	26/3237	115/18639	0.226086956521739	1.30183342063908	0.0891537539318332	0.417537071996798
GO:0140801	histone H2AXY142 kinase activity	26/3237	115/18639	0.226086956521739	1.30183342063908	0.0891537539318332	0.417537071996798
GO:0042171	lysophosphatidic acid acyltransferase activity	7/3237	23/18639	0.304347826086957	1.75246806624491	0.0895395526855436	0.417537071996798
GO:0071617	lysophospholipid acyltransferase activity	7/3237	23/18639	0.304347826086957	1.75246806624491	0.0895395526855436	0.417537071996798
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	7/3237	23/18639	0.304347826086957	1.75246806624491	0.0895395526855436	0.417537071996798
GO:0042578	phosphoric ester hydrolase activity	73/3237	363/18639	0.201101928374656	1.15796689619253	0.0944983547798603	0.439119977281239
GO:0140036	ubiquitin-modified protein reader activity	6/3237	19/18639	0.315789473684211	1.81835032437442	0.0967111127791099	0.447836476945774
GO:0016791	phosphatase activity	56/3237	273/18639	0.205128205128205	1.18115063805518	0.0982775682135682	0.451938580615364
GO:0051019	mitogen-activated protein kinase binding	8/3237	28/18639	0.285714285714286	1.64517410300543	0.0986171470116294	0.451938580615364
GO:0051537	2 iron, 2 sulfur cluster binding	8/3237	28/18639	0.285714285714286	1.64517410300543	0.0986171470116294	0.451938580615364
GO:0016922	nuclear receptor binding	30/3237	137/18639	0.218978102189781	1.26089985996766	0.100557393801914	0.459246654167506
GO:0001784	phosphotyrosine residue binding	12/3237	47/18639	0.25531914893617	1.47015558140911	0.1026497020211	0.461370750831148
GO:0061733	protein-lysine-acetyltransferase activity	12/3237	47/18639	0.25531914893617	1.47015558140911	0.1026497020211	0.461370750831148
GO:0061749	forked DNA-dependent helicase activity	12/3237	47/18639	0.25531914893617	1.47015558140911	0.1026497020211	0.461370750831148
GO:0017081	chloride channel regulator activity	5/3237	15/18639	0.333333333333333	1.91936978683967	0.103329430040582	0.461370750831148
GO:0033130	acetylcholine receptor binding	5/3237	15/18639	0.333333333333333	1.91936978683967	0.103329430040582	0.461370750831148
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	27/3237	122/18639	0.221311475409836	1.27433567814765	0.103725060927638	0.461370750831148
GO:0071889	14-3-3 protein binding	9/3237	33/18639	0.272727272727273	1.57039346195973	0.105266230013094	0.461370750831148
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0008199	ferric iron binding	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0019203	carbohydrate phosphatase activity	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0019206	nucleoside kinase activity	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0019864	IgG binding	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0034056	estrogen response element binding	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0048185	activin binding	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0070990	snRNP binding	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0140537	transcription regulator activator activity	4/3237	11/18639	0.363636363636364	2.09385794927964	0.107846594558409	0.461370750831148
GO:0001091	RNA polymerase II general transcription initiation factor binding	7/3237	24/18639	0.291666666666667	1.67944856348471	0.108312772204152	0.461370750831148
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	7/3237	24/18639	0.291666666666667	1.67944856348471	0.108312772204152	0.461370750831148
GO:0035035	histone acetyltransferase binding	7/3237	24/18639	0.291666666666667	1.67944856348471	0.108312772204152	0.461370750831148
GO:0060229	lipase activator activity	7/3237	24/18639	0.291666666666667	1.67944856348471	0.108312772204152	0.461370750831148
GO:0070300	phosphatidic acid binding	7/3237	24/18639	0.291666666666667	1.67944856348471	0.108312772204152	0.461370750831148
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	16/3237	67/18639	0.238805970149254	1.37507089206424	0.108680443507852	0.461457857578068
GO:0008200	ion channel inhibitor activity	11/3237	43/18639	0.255813953488372	1.47300472013277	0.113719655668937	0.479788642488945
GO:0008375	acetylglucosaminyltransferase activity	11/3237	43/18639	0.255813953488372	1.47300472013277	0.113719655668937	0.479788642488945
GO:0019903	protein phosphatase binding	31/3237	144/18639	0.215277777777778	1.23959298733395	0.114368882003112	0.481000772728277
GO:0140101	catalytic activity, acting on a tRNA	30/3237	139/18639	0.215827338129496	1.24275741593935	0.115894007988144	0.485877402574898
GO:0009378	four-way junction helicase activity	12/3237	48/18639	0.25	1.43952734012975	0.11629056588178	0.486006798921024
GO:0003689	DNA clamp loader activity	34/3237	160/18639	0.2125	1.22359823911029	0.117142150029821	0.487790974693832
GO:0034212	protein N-acetyltransferase activity	13/3237	53/18639	0.245283018867925	1.41236644691975	0.118089272359214	0.487790974693832
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/3237	20/18639	0.3	1.7274328081557	0.118782874250262	0.487790974693832
GO:0016004	phospholipase activator activity	6/3237	20/18639	0.3	1.7274328081557	0.118782874250262	0.487790974693832
GO:0042288	MHC class I protein binding	6/3237	20/18639	0.3	1.7274328081557	0.118782874250262	0.487790974693832
GO:0035591	signaling adaptor activity	28/3237	129/18639	0.217054263565891	1.24982218677932	0.118919695862153	0.487790974693832
GO:0030165	PDZ domain binding	19/3237	83/18639	0.228915662650602	1.31812141987784	0.119646370700869	0.489261620496783
GO:0003713	transcription coactivator activity	52/3237	256/18639	0.203125	1.16961596385542	0.122171073786422	0.498053242521946
GO:0016757	glycosyltransferase activity	54/3237	267/18639	0.202247191011236	1.16456144370047	0.123997953331675	0.503954984641577
GO:0000510	H3-H4 histone complex chaperone activity	32/3237	151/18639	0.211920529801325	1.22026158633515	0.128675924616845	0.507263556649113
GO:0140584	chromatin extrusion motor activity	32/3237	151/18639	0.211920529801325	1.22026158633515	0.128675924616845	0.507263556649113
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	32/3237	151/18639	0.211920529801325	1.22026158633515	0.128675924616845	0.507263556649113
GO:0140849	ATP-dependent H2AZ histone chaperone activity	32/3237	151/18639	0.211920529801325	1.22026158633515	0.128675924616845	0.507263556649113
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	7/3237	25/18639	0.28	1.61227062094532	0.129000460075495	0.507263556649113
GO:0047617	fatty acyl-CoA hydrolase activity	7/3237	25/18639	0.28	1.61227062094532	0.129000460075495	0.507263556649113
GO:0001223	transcription coactivator binding	11/3237	44/18639	0.25	1.43952734012975	0.129047861181373	0.507263556649113
GO:0016248	channel inhibitor activity	11/3237	44/18639	0.25	1.43952734012975	0.129047861181373	0.507263556649113
GO:0019205	nucleobase-containing compound kinase activity	11/3237	44/18639	0.25	1.43952734012975	0.129047861181373	0.507263556649113
GO:0005159	insulin-like growth factor receptor binding	5/3237	16/18639	0.3125	1.79940917516219	0.12977397235568	0.507263556649113
GO:0005521	lamin binding	5/3237	16/18639	0.3125	1.79940917516219	0.12977397235568	0.507263556649113
GO:0008296	3'-5'-DNA exonuclease activity	5/3237	16/18639	0.3125	1.79940917516219	0.12977397235568	0.507263556649113
GO:0034450	ubiquitin-ubiquitin ligase activity	5/3237	16/18639	0.3125	1.79940917516219	0.12977397235568	0.507263556649113
GO:0140463	chromatin-protein adaptor activity	13/3237	54/18639	0.240740740740741	1.38621151271754	0.13207254104007	0.514734331502206
GO:0004879	nuclear receptor activity	14/3237	59/18639	0.23728813559322	1.36633103469942	0.132674449387335	0.515568255075344
GO:0008106	alcohol dehydrogenase (NADP+) activity	8/3237	30/18639	0.266666666666667	1.53549582947173	0.135872458520771	0.518654270267175
GO:0031624	ubiquitin conjugating enzyme binding	8/3237	30/18639	0.266666666666667	1.53549582947173	0.135872458520771	0.518654270267175
GO:0051721	protein phosphatase 2A binding	8/3237	30/18639	0.266666666666667	1.53549582947173	0.135872458520771	0.518654270267175
GO:0031072	heat shock protein binding	28/3237	131/18639	0.213740458015267	1.23074093201933	0.136641312122031	0.518654270267175
GO:0015616	DNA translocase activity	32/3237	152/18639	0.210526315789474	1.21223354958295	0.137081091322776	0.518654270267175
GO:0140674	ATP-dependent histone chaperone activity	32/3237	152/18639	0.210526315789474	1.21223354958295	0.137081091322776	0.518654270267175
GO:0005049	nuclear export signal receptor activity	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0005527	macrolide binding	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0070008	serine-type exopeptidase activity	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/3237	12/18639	0.333333333333333	1.91936978683967	0.140471074275906	0.518654270267175
GO:0000175	3'-5'-RNA exonuclease activity	9/3237	35/18639	0.257142857142857	1.48065669270489	0.140493256054314	0.518654270267175
GO:0004623	phospholipase A2 activity	9/3237	35/18639	0.257142857142857	1.48065669270489	0.140493256054314	0.518654270267175
GO:0016229	steroid dehydrogenase activity	9/3237	35/18639	0.257142857142857	1.48065669270489	0.140493256054314	0.518654270267175
GO:0034061	DNA polymerase activity	9/3237	35/18639	0.257142857142857	1.48065669270489	0.140493256054314	0.518654270267175
GO:0010314	phosphatidylinositol-5-phosphate binding	6/3237	21/18639	0.285714285714286	1.64517410300543	0.143105001505081	0.522633891891761
GO:0035613	RNA stem-loop binding	6/3237	21/18639	0.285714285714286	1.64517410300543	0.143105001505081	0.522633891891761
GO:0140312	cargo adaptor activity	6/3237	21/18639	0.285714285714286	1.64517410300543	0.143105001505081	0.522633891891761
GO:0004532	RNA exonuclease activity	10/3237	40/18639	0.25	1.43952734012975	0.143537524861168	0.522633891891761
GO:0071949	FAD binding	10/3237	40/18639	0.25	1.43952734012975	0.143537524861168	0.522633891891761
GO:0008009	chemokine activity	11/3237	45/18639	0.244444444444444	1.40753784368242	0.145442977488583	0.523304791855665
GO:0141110	transporter inhibitor activity	11/3237	45/18639	0.244444444444444	1.40753784368242	0.145442977488583	0.523304791855665
GO:0061775	cohesin loader activity	32/3237	153/18639	0.209150326797386	1.20431045448763	0.14580916298323	0.523304791855665
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	28/3237	132/18639	0.212121212121212	1.22141713707979	0.146062909720998	0.523304791855665
GO:0160215	deacylase activity	15/3237	65/18639	0.230769230769231	1.32879446781208	0.14643393912413	0.523304791855665
GO:0001098	basal transcription machinery binding	14/3237	60/18639	0.233333333333333	1.34355885078777	0.146871849030973	0.523304791855665
GO:0001099	basal RNA polymerase II transcription machinery binding	14/3237	60/18639	0.233333333333333	1.34355885078777	0.146871849030973	0.523304791855665
GO:0098531	ligand-modulated transcription factor activity	14/3237	60/18639	0.233333333333333	1.34355885078777	0.146871849030973	0.523304791855665
GO:0042826	histone deacetylase binding	27/3237	127/18639	0.21259842519685	1.22416498215758	0.148372436542671	0.52723788279468
GO:0004896	cytokine receptor activity	21/3237	96/18639	0.21875	1.25958642261353	0.150700825874471	0.534059291082512
GO:0016289	acyl-CoA hydrolase activity	7/3237	26/18639	0.269230769230769	1.55026021244742	0.151497631857116	0.534059291082512
GO:0070412	R-SMAD binding	7/3237	26/18639	0.269230769230769	1.55026021244742	0.151497631857116	0.534059291082512
GO:0004721	phosphoprotein phosphatase activity	36/3237	175/18639	0.205714285714286	1.18452535416391	0.15295368961327	0.537765749989513
GO:0016411	acylglycerol O-acyltransferase activity	8/3237	31/18639	0.258064516129032	1.48596370594039	0.15681325572423	0.545728389546559
GO:0047499	calcium-independent phospholipase A2 activity	8/3237	31/18639	0.258064516129032	1.48596370594039	0.15681325572423	0.545728389546559
GO:0070273	phosphatidylinositol-4-phosphate binding	8/3237	31/18639	0.258064516129032	1.48596370594039	0.15681325572423	0.545728389546559
GO:0008429	phosphatidylethanolamine binding	5/3237	17/18639	0.294117647058824	1.69356157662324	0.158914136007914	0.545728389546559
GO:0015278	intracellularly gated calcium channel activity	5/3237	17/18639	0.294117647058824	1.69356157662324	0.158914136007914	0.545728389546559
GO:0030169	low-density lipoprotein particle binding	5/3237	17/18639	0.294117647058824	1.69356157662324	0.158914136007914	0.545728389546559
GO:0038191	neuropilin binding	5/3237	17/18639	0.294117647058824	1.69356157662324	0.158914136007914	0.545728389546559
GO:0051787	misfolded protein binding	5/3237	17/18639	0.294117647058824	1.69356157662324	0.158914136007914	0.545728389546559
GO:0070403	NAD+ binding	5/3237	17/18639	0.294117647058824	1.69356157662324	0.158914136007914	0.545728389546559
GO:0140299	molecular sensor activity	16/3237	71/18639	0.225352112676056	1.29760210941273	0.159414977965586	0.54603738586666
GO:0019905	syntaxin binding	14/3237	61/18639	0.229508196721311	1.32153329585682	0.161852061345336	0.552959870251805
GO:0030291	protein serine/threonine kinase inhibitor activity	11/3237	46/18639	0.239130434782609	1.37693919490672	0.162865197610918	0.554994481089513
GO:0008649	rRNA methyltransferase activity	6/3237	22/18639	0.272727272727273	1.57039346195973	0.169487856851613	0.569651754076416
GO:0031683	G-protein beta/gamma-subunit complex binding	6/3237	22/18639	0.272727272727273	1.57039346195973	0.169487856851613	0.569651754076416
GO:0034062	5'-3' RNA polymerase activity	6/3237	22/18639	0.272727272727273	1.57039346195973	0.169487856851613	0.569651754076416
GO:0046972	histone H4K16 acetyltransferase activity	6/3237	22/18639	0.272727272727273	1.57039346195973	0.169487856851613	0.569651754076416
GO:0097747	RNA polymerase activity	6/3237	22/18639	0.272727272727273	1.57039346195973	0.169487856851613	0.569651754076416
GO:0004722	protein serine/threonine phosphatase activity	22/3237	103/18639	0.213592233009709	1.22988743622736	0.172034150751593	0.569651754076416
GO:0004725	protein tyrosine phosphatase activity	21/3237	98/18639	0.214285714285714	1.23388057725407	0.174829105059019	0.569651754076416
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	7/3237	27/18639	0.259259259259259	1.49284316754196	0.175668705384848	0.569651754076416
GO:0035255	ionotropic glutamate receptor binding	7/3237	27/18639	0.259259259259259	1.49284316754196	0.175668705384848	0.569651754076416
GO:0050840	extracellular matrix binding	15/3237	67/18639	0.223880597014925	1.28912896131022	0.175773172444213	0.569651754076416
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0005542	folic acid binding	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0008035	high-density lipoprotein particle binding	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0017154	semaphorin receptor activity	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0019104	DNA N-glycosylase activity	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0030955	potassium ion binding	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0043560	insulin receptor substrate binding	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0051011	microtubule minus-end binding	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0097157	pre-mRNA intronic binding	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0140666	annealing activity	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	4/3237	13/18639	0.307692307692308	1.77172595708277	0.176420412388765	0.569651754076416
GO:0008094	ATP-dependent activity, acting on DNA	42/3237	210/18639	0.2	1.1516218721038	0.177556701458269	0.569651754076416
GO:0031369	translation initiation factor binding	8/3237	32/18639	0.25	1.43952734012975	0.179168121297172	0.569651754076416
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/3237	32/18639	0.25	1.43952734012975	0.179168121297172	0.569651754076416
GO:0070717	poly-purine tract binding	8/3237	32/18639	0.25	1.43952734012975	0.179168121297172	0.569651754076416
GO:0071813	lipoprotein particle binding	8/3237	32/18639	0.25	1.43952734012975	0.179168121297172	0.569651754076416
GO:0071814	protein-lipid complex binding	8/3237	32/18639	0.25	1.43952734012975	0.179168121297172	0.569651754076416
GO:0120015	sterol transfer activity	8/3237	32/18639	0.25	1.43952734012975	0.179168121297172	0.569651754076416
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/3237	47/18639	0.234042553191489	1.34764261629168	0.181264376818918	0.574941185661913
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	18/3237	83/18639	0.216867469879518	1.24874660830533	0.183259918521313	0.579886742178155
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/3237	18/18639	0.277777777777778	1.59947482236639	0.190406832885611	0.597324421812135
GO:0035615	clathrin adaptor activity	5/3237	18/18639	0.277777777777778	1.59947482236639	0.190406832885611	0.597324421812135
GO:0050811	GABA receptor binding	5/3237	18/18639	0.277777777777778	1.59947482236639	0.190406832885611	0.597324421812135
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	15/3237	68/18639	0.220588235294118	1.27017118246743	0.19146742189012	0.597324421812135
GO:0030145	manganese ion binding	15/3237	68/18639	0.220588235294118	1.27017118246743	0.19146742189012	0.597324421812135
GO:1990841	promoter-specific chromatin binding	15/3237	68/18639	0.220588235294118	1.27017118246743	0.19146742189012	0.597324421812135
GO:0140658	ATP-dependent chromatin remodeler activity	32/3237	158/18639	0.20253164556962	1.16619936415575	0.194159458399849	0.601713448117124
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	19/3237	89/18639	0.213483146067416	1.22925930168383	0.194232557744354	0.601713448117124
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	19/3237	89/18639	0.213483146067416	1.22925930168383	0.194232557744354	0.601713448117124
GO:0004602	glutathione peroxidase activity	6/3237	23/18639	0.260869565217391	1.50211548535278	0.197704905380813	0.607660677730735
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/3237	23/18639	0.260869565217391	1.50211548535278	0.197704905380813	0.607660677730735
GO:0140102	catalytic activity, acting on a rRNA	6/3237	23/18639	0.260869565217391	1.50211548535278	0.197704905380813	0.607660677730735
GO:0003774	cytoskeletal motor activity	31/3237	153/18639	0.202614379084967	1.1666757527849	0.1979812441365	0.607660677730735
GO:0005544	calcium-dependent phospholipid binding	12/3237	53/18639	0.226415094339623	1.30372287407977	0.198676258933597	0.608388820559333
GO:0043138	3'-5' DNA helicase activity	11/3237	48/18639	0.229166666666667	1.31956672845227	0.200580915205635	0.609561616892478
GO:0019789	SUMO transferase activity	7/3237	28/18639	0.25	1.43952734012975	0.20135255817592	0.609561616892478
GO:0045499	chemorepellent activity	7/3237	28/18639	0.25	1.43952734012975	0.20135255817592	0.609561616892478
GO:0046966	nuclear thyroid hormone receptor binding	7/3237	28/18639	0.25	1.43952734012975	0.20135255817592	0.609561616892478
GO:0097718	disordered domain specific binding	7/3237	28/18639	0.25	1.43952734012975	0.20135255817592	0.609561616892478
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	9/3237	38/18639	0.236842105263158	1.36376274328082	0.202893226277195	0.612829767550891
GO:0008080	N-acetyltransferase activity	15/3237	69/18639	0.217391304347826	1.25176290446065	0.207801720849544	0.626232396845905
GO:0140793	histone H2AXY142 phosphatase activity	19/3237	90/18639	0.211111111111111	1.21560086499846	0.208509814401906	0.626944668190346
GO:0001786	phosphatidylserine binding	13/3237	59/18639	0.220338983050847	1.26873596079232	0.214494451055697	0.633684567203596
GO:0070063	RNA polymerase binding	13/3237	59/18639	0.220338983050847	1.26873596079232	0.214494451055697	0.633684567203596
GO:1990782	protein tyrosine kinase binding	24/3237	117/18639	0.205128205128205	1.18115063805518	0.214986657172177	0.633684567203596
GO:0005161	platelet-derived growth factor receptor binding	4/3237	14/18639	0.285714285714286	1.64517410300543	0.215042693610852	0.633684567203596
GO:0019763	immunoglobulin receptor activity	4/3237	14/18639	0.285714285714286	1.64517410300543	0.215042693610852	0.633684567203596
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	4/3237	14/18639	0.285714285714286	1.64517410300543	0.215042693610852	0.633684567203596
GO:0032036	myosin heavy chain binding	4/3237	14/18639	0.285714285714286	1.64517410300543	0.215042693610852	0.633684567203596
GO:0044548	S100 protein binding	4/3237	14/18639	0.285714285714286	1.64517410300543	0.215042693610852	0.633684567203596
GO:1901612	cardiolipin binding	4/3237	14/18639	0.285714285714286	1.64517410300543	0.215042693610852	0.633684567203596
GO:0035254	glutamate receptor binding	11/3237	49/18639	0.224489795918367	1.29263679521855	0.220746775583706	0.644168475484328
GO:0060590	ATPase regulator activity	11/3237	49/18639	0.224489795918367	1.29263679521855	0.220746775583706	0.644168475484328
GO:0015399	primary active transmembrane transporter activity	33/3237	166/18639	0.198795180722892	1.14468439094655	0.22212819330391	0.644168475484328
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/3237	19/18639	0.263157894736842	1.51529193697868	0.223869590066505	0.644168475484328
GO:0008301	DNA binding, bending	5/3237	19/18639	0.263157894736842	1.51529193697868	0.223869590066505	0.644168475484328
GO:0031420	alkali metal ion binding	5/3237	19/18639	0.263157894736842	1.51529193697868	0.223869590066505	0.644168475484328
GO:0050145	nucleoside monophosphate kinase activity	5/3237	19/18639	0.263157894736842	1.51529193697868	0.223869590066505	0.644168475484328
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0015295	solute:proton symporter activity	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0043998	histone H2A acetyltransferase activity	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0050699	WW domain binding	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0070840	dynein complex binding	6/3237	24/18639	0.25	1.43952734012975	0.227502283106367	0.644168475484328
GO:0008376	acetylgalactosaminyltransferase activity	8/3237	34/18639	0.235294117647059	1.35484926129859	0.227623182400773	0.644168475484328
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/3237	34/18639	0.235294117647059	1.35484926129859	0.227623182400773	0.644168475484328
GO:0050660	flavin adenine dinucleotide binding	18/3237	86/18639	0.209302325581395	1.20518568010863	0.227809769358641	0.644168475484328
GO:0051861	glycolipid binding	7/3237	29/18639	0.241379310344828	1.38988846633217	0.228367894936257	0.64437565259084
GO:0140034	methylation-dependent protein binding	16/3237	76/18639	0.210526315789474	1.21223354958295	0.237294432306632	0.647977590028211
GO:0008374	O-acyltransferase activity	12/3237	55/18639	0.218181818181818	1.25631476956778	0.237456678588575	0.647977590028211
GO:0061135	endopeptidase regulator activity	36/3237	184/18639	0.195652173913043	1.12658661401459	0.240679805689187	0.647977590028211
GO:0016298	lipase activity	26/3237	130/18639	0.2	1.1516218721038	0.24430529403513	0.647977590028211
GO:0000182	rDNA binding	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0001094	TFIID-class transcription factor complex binding	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0005345	purine nucleobase transmembrane transporter activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0008190	eukaryotic initiation factor 4E binding	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0015279	store-operated calcium channel activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0071723	lipopeptide binding	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0097177	mitochondrial ribosome binding	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0099122	RNA polymerase II C-terminal domain binding	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:1990763	arrestin family protein binding	3/3237	10/18639	0.3	1.7274328081557	0.244514679829122	0.647977590028211
GO:0046915	transition metal ion transmembrane transporter activity	10/3237	45/18639	0.222222222222222	1.27957985789311	0.245829950204633	0.647977590028211
GO:0005125	cytokine activity	45/3237	234/18639	0.192307692307692	1.10732872317673	0.248031756984686	0.647977590028211
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	17/3237	82/18639	0.207317073170732	1.19375437961979	0.248969481091839	0.647977590028211
GO:0030331	nuclear estrogen receptor binding	9/3237	40/18639	0.225	1.29557460611677	0.249795959788038	0.647977590028211
GO:0044325	transmembrane transporter binding	27/3237	136/18639	0.198529411764706	1.14315406422068	0.251941925531799	0.647977590028211
GO:0140789	histone phosphatase activity	27/3237	136/18639	0.198529411764706	1.14315406422068	0.251941925531799	0.647977590028211
GO:0004620	phospholipase activity	22/3237	109/18639	0.201834862385321	1.16218721037998	0.252276350615003	0.647977590028211
GO:0015026	coreceptor activity	13/3237	61/18639	0.213114754098361	1.22713806043848	0.252521589140198	0.647977590028211
GO:0005516	calmodulin binding	40/3237	207/18639	0.193236714975845	1.11267813729836	0.252626564636625	0.647977590028211
GO:0010485	histone H4 acetyltransferase activity	8/3237	35/18639	0.228571428571429	1.31613928240434	0.253439456873798	0.647977590028211
GO:0140566	histone reader activity	8/3237	35/18639	0.228571428571429	1.31613928240434	0.253439456873798	0.647977590028211
GO:0003724	RNA helicase activity	16/3237	77/18639	0.207792207792208	1.19649025673122	0.254506911977645	0.647977590028211
GO:0004129	cytochrome-c oxidase activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0008242	omega peptidase activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0015929	hexosaminidase activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0016846	carbon-sulfur lyase activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0031386	protein tag activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0048531	beta-1,3-galactosyltransferase activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0050700	CARD domain binding	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0050780	dopamine receptor binding	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0061578	K63-linked deubiquitinase activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0141047	molecular tag activity	4/3237	15/18639	0.266666666666667	1.53549582947173	0.255665698545496	0.647977590028211
GO:0015215	nucleotide transmembrane transporter activity	7/3237	30/18639	0.233333333333333	1.34355885078777	0.256518679932275	0.647977590028211
GO:0070566	adenylyltransferase activity	7/3237	30/18639	0.233333333333333	1.34355885078777	0.256518679932275	0.647977590028211
GO:0019212	phosphatase inhibitor activity	12/3237	56/18639	0.214285714285714	1.23388057725407	0.257860811292133	0.647977590028211
GO:0000030	mannosyltransferase activity	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0005537	D-mannose binding	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0015662	P-type ion transporter activity	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0019211	phosphatase activator activity	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0019706	protein-cysteine S-palmitoyltransferase activity	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0019707	protein-cysteine S-acyltransferase activity	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0042974	nuclear retinoic acid receptor binding	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0120020	cholesterol transfer activity	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0140358	P-type transmembrane transporter activity	6/3237	25/18639	0.24	1.38194624652456	0.258608121958221	0.647977590028211
GO:0010851	cyclase regulator activity	5/3237	20/18639	0.25	1.43952734012975	0.258898495338585	0.647977590028211
GO:0016505	peptidase activator activity involved in apoptotic process	5/3237	20/18639	0.25	1.43952734012975	0.258898495338585	0.647977590028211
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	5/3237	20/18639	0.25	1.43952734012975	0.258898495338585	0.647977590028211
GO:0052745	inositol phosphate phosphatase activity	5/3237	20/18639	0.25	1.43952734012975	0.258898495338585	0.647977590028211
GO:0141108	transporter regulator activity	33/3237	170/18639	0.194117647058824	1.11775064057134	0.267954927479605	0.6693836440233
GO:0004180	carboxypeptidase activity	10/3237	46/18639	0.217391304347826	1.25176290446065	0.268875714813999	0.670423686656294
GO:0042287	MHC protein binding	9/3237	41/18639	0.219512195121951	1.26397522547978	0.274494340126611	0.68315164424769
GO:0003779	actin binding	82/3237	443/18639	0.18510158013544	1.06583514122474	0.278221348687562	0.690313696455588
GO:0099106	ion channel regulator activity	31/3237	160/18639	0.19375	1.11563368860056	0.279727300467386	0.690313696455588
GO:0000993	RNA polymerase II complex binding	8/3237	36/18639	0.222222222222222	1.27957985789311	0.280108803521209	0.690313696455588
GO:0004033	aldo-keto reductase (NADPH) activity	8/3237	36/18639	0.222222222222222	1.27957985789311	0.280108803521209	0.690313696455588
GO:0016409	palmitoyltransferase activity	8/3237	36/18639	0.222222222222222	1.27957985789311	0.280108803521209	0.690313696455588
GO:0019955	cytokine binding	28/3237	144/18639	0.194444444444444	1.11963237565647	0.285498842751811	0.690313696455588
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	11/3237	52/18639	0.211538461538462	1.2180615954944	0.285557380535377	0.690313696455588
GO:0070325	lipoprotein particle receptor binding	7/3237	31/18639	0.225806451612903	1.30021824269784	0.285599428659621	0.690313696455588
GO:0072349	modified amino acid transmembrane transporter activity	7/3237	31/18639	0.225806451612903	1.30021824269784	0.285599428659621	0.690313696455588
GO:0003712	transcription coregulator activity	91/3237	495/18639	0.183838383838384	1.05856151880248	0.28982083336014	0.690313696455588
GO:0008186	ATP-dependent activity, acting on RNA	16/3237	79/18639	0.20253164556962	1.16619936415575	0.290252220490221	0.690313696455588
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/3237	26/18639	0.230769230769231	1.32879446781208	0.290741268988553	0.690313696455588
GO:0008143	poly(A) binding	6/3237	26/18639	0.230769230769231	1.32879446781208	0.290741268988553	0.690313696455588
GO:0019865	immunoglobulin binding	6/3237	26/18639	0.230769230769231	1.32879446781208	0.290741268988553	0.690313696455588
GO:0043495	protein-membrane adaptor activity	10/3237	47/18639	0.212765957446809	1.22512965117426	0.292554454812669	0.690313696455588
GO:0070182	DNA polymerase binding	5/3237	21/18639	0.238095238095238	1.37097841917119	0.295083962161556	0.690313696455588
GO:0072542	protein phosphatase activator activity	5/3237	21/18639	0.238095238095238	1.37097841917119	0.295083962161556	0.690313696455588
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0003953	NAD+ nucleosidase activity	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0015173	aromatic amino acid transmembrane transporter activity	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0015205	nucleobase transmembrane transporter activity	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0032050	clathrin heavy chain binding	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0034713	type I transforming growth factor beta receptor binding	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0050998	nitric-oxide synthase binding	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0180030	inositol phosphate kinase activity	3/3237	11/18639	0.272727272727273	1.57039346195973	0.29576521180564	0.690313696455588
GO:0035064	methylated histone binding	15/3237	74/18639	0.202702702702703	1.16718432983493	0.297626772728313	0.690313696455588
GO:0003688	DNA replication origin binding	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0005149	interleukin-1 receptor binding	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0008142	oxysterol binding	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0043023	ribosomal large subunit binding	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0055102	lipase inhibitor activity	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0140328	floppase activity	4/3237	16/18639	0.25	1.43952734012975	0.297629607275434	0.690313696455588
GO:0004402	histone acetyltransferase activity	9/3237	42/18639	0.214285714285714	1.23388057725407	0.299854151279259	0.69185098446204
GO:0004520	DNA endonuclease activity	9/3237	42/18639	0.214285714285714	1.23388057725407	0.299854151279259	0.69185098446204
GO:0043175	RNA polymerase core enzyme binding	9/3237	42/18639	0.214285714285714	1.23388057725407	0.299854151279259	0.69185098446204
GO:0001216	DNA-binding transcription activator activity	90/3237	491/18639	0.183299389002037	1.05545792759004	0.301639449217352	0.69476400001709
GO:0019213	deacetylase activity	8/3237	37/18639	0.216216216216216	1.24499661849059	0.307469098158268	0.706966144381208
GO:0072341	modified amino acid binding	18/3237	91/18639	0.197802197802198	1.13896668669607	0.310828053949952	0.712104675463363
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	43/3237	229/18639	0.187772925764192	1.08121704149483	0.31087314638716	0.712104675463363
GO:0016247	channel regulator activity	32/3237	168/18639	0.19047619047619	1.09678273533695	0.311311374299634	0.712104675463363
GO:0043425	bHLH transcription factor binding	7/3237	32/18639	0.21875	1.25958642261353	0.315400194721106	0.718982605118954
GO:0047498	calcium-dependent phospholipase A2 activity	7/3237	32/18639	0.21875	1.25958642261353	0.315400194721106	0.718982605118954
GO:0019003	GDP binding	15/3237	75/18639	0.2	1.1516218721038	0.316888795353912	0.721139056550255
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/3237	59/18639	0.203389830508475	1.17114088688522	0.322253404003424	0.723376863731978
GO:0016853	isomerase activity	34/3237	180/18639	0.188888888888889	1.08764287920914	0.322900549860554	0.723376863731978
GO:0001671	ATPase activator activity	6/3237	27/18639	0.222222222222222	1.27957985789311	0.323619144303897	0.723376863731978
GO:0042393	histone binding	46/3237	247/18639	0.186234817813765	1.07236044770799	0.324699785135339	0.723376863731978
GO:0033192	calmodulin-dependent protein phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:0140791	histone H2AXS140 phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/3237	81/18639	0.197530864197531	1.13740431812721	0.3274534013808	0.723376863731978
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0032931	histone H3K56 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0043992	histone H3K9 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0043993	histone H3K18 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0043994	histone H3K23 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0043999	histone H2AK5 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0044012	histone H2AK9 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0044014	histone H2BK5 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0044015	histone H2BK12 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0044016	histone H3K4 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0044017	histone H3K27 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0044018	histone H3K36 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0140784	metal ion sensor activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0140908	histone H3K122 acetyltransferase activity	5/3237	22/18639	0.227272727272727	1.30866121829977	0.332023993135069	0.723376863731978
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	88/3237	484/18639	0.181818181818182	1.04692897463982	0.333942677989345	0.726366315953911
GO:0005109	frizzled binding	8/3237	38/18639	0.210526315789474	1.21223354958295	0.335355997326554	0.72824856282188
GO:0017022	myosin binding	15/3237	76/18639	0.197368421052632	1.13646895273401	0.3364611797098	0.728299042506603
GO:0008170	N-methyltransferase activity	19/3237	98/18639	0.193877551020408	1.11636814132511	0.337303217375446	0.728299042506603
GO:0061134	peptidase regulator activity	42/3237	226/18639	0.185840707964602	1.07009112009645	0.339685297421288	0.728299042506603
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/3237	17/18639	0.235294117647059	1.35484926129859	0.340311290742363	0.728299042506603
GO:0004549	tRNA-specific ribonuclease activity	4/3237	17/18639	0.235294117647059	1.35484926129859	0.340311290742363	0.728299042506603
GO:0004550	nucleoside diphosphate kinase activity	4/3237	17/18639	0.235294117647059	1.35484926129859	0.340311290742363	0.728299042506603
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/3237	17/18639	0.235294117647059	1.35484926129859	0.340311290742363	0.728299042506603
GO:0046965	nuclear retinoid X receptor binding	4/3237	17/18639	0.235294117647059	1.35484926129859	0.340311290742363	0.728299042506603
GO:1990226	histone methyltransferase binding	4/3237	17/18639	0.235294117647059	1.35484926129859	0.340311290742363	0.728299042506603
GO:0003714	transcription corepressor activity	38/3237	204/18639	0.186274509803922	1.07258899852805	0.343955523764174	0.728497270371245
GO:0033549	MAP kinase phosphatase activity	16/3237	82/18639	0.195121951219512	1.1235335337598	0.346479806299337	0.728497270371245
GO:0005247	voltage-gated chloride channel activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0008179	adenylate cyclase binding	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0010853	cyclase activator activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0015269	calcium-activated potassium channel activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0016273	arginine N-methyltransferase activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0016274	protein-arginine N-methyltransferase activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0016840	carbon-nitrogen lyase activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0034452	dynactin binding	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0042301	phosphate ion binding	3/3237	12/18639	0.25	1.43952734012975	0.347529924315553	0.728497270371245
GO:0030547	signaling receptor inhibitor activity	9/3237	44/18639	0.204545454545455	1.1777950964698	0.352028945779984	0.735607655568552
GO:0043014	alpha-tubulin binding	9/3237	44/18639	0.204545454545455	1.1777950964698	0.352028945779984	0.735607655568552
GO:0019783	ubiquitin-like protein peptidase activity	24/3237	127/18639	0.188976377952756	1.08814665080674	0.358844480829249	0.748672394069188
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/3237	39/18639	0.205128205128205	1.18115063805518	0.36360585162257	0.757417205025699
GO:0048020	CCR chemokine receptor binding	10/3237	50/18639	0.2	1.1516218721038	0.366298705170362	0.761498489174904
GO:0042379	chemokine receptor binding	14/3237	72/18639	0.194444444444444	1.11963237565647	0.366711085832911	0.761498489174904
GO:0000295	adenine nucleotide transmembrane transporter activity	5/3237	23/18639	0.217391304347826	1.25176290446065	0.369334850844584	0.762183255857844
GO:0008171	O-methyltransferase activity	5/3237	23/18639	0.217391304347826	1.25176290446065	0.369334850844584	0.762183255857844
GO:0043274	phospholipase binding	5/3237	23/18639	0.217391304347826	1.25176290446065	0.369334850844584	0.762183255857844
GO:0044013	histone H2B acetyltransferase activity	5/3237	23/18639	0.217391304347826	1.25176290446065	0.369334850844584	0.762183255857844
GO:1902936	phosphatidylinositol bisphosphate binding	21/3237	111/18639	0.189189189189189	1.08937204117927	0.370107908308431	0.762594434328535
GO:0070851	growth factor receptor binding	26/3237	139/18639	0.18705035971223	1.07705642714744	0.371705847588859	0.763519430364133
GO:0140767	enzyme-substrate adaptor activity	26/3237	139/18639	0.18705035971223	1.07705642714744	0.371705847588859	0.763519430364133
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	24/3237	128/18639	0.1875	1.07964550509731	0.374416528754835	0.76676338385539
GO:0003727	single-stranded RNA binding	17/3237	89/18639	0.191011235955056	1.09986358571711	0.374439003854137	0.76676338385539
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/3237	34/18639	0.205882352941176	1.18549310363626	0.376326521896323	0.768261056221525
GO:0030332	cyclin binding	7/3237	34/18639	0.205882352941176	1.18549310363626	0.376326521896323	0.768261056221525
GO:0042054	histone methyltransferase activity	13/3237	67/18639	0.194029850746269	1.11724509980219	0.37783283926734	0.769176086913997
GO:0008276	protein methyltransferase activity	18/3237	95/18639	0.189473684210526	1.09101019462465	0.382532863863284	0.769176086913997
GO:0008308	voltage-gated monoatomic anion channel activity	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0008409	5'-3' exonuclease activity	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0017075	syntaxin-1 binding	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0031690	adrenergic receptor binding	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0034185	apolipoprotein binding	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0070064	proline-rich region binding	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:1901611	phosphatidylglycerol binding	4/3237	18/18639	0.222222222222222	1.27957985789311	0.383141135844293	0.769176086913997
GO:0017018	myosin phosphatase activity	16/3237	84/18639	0.19047619047619	1.09678273533695	0.385135947450516	0.772014591495831
GO:0033218	amide binding	45/3237	247/18639	0.182186234817814	1.04904826406217	0.386787850033082	0.774158211888503
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/3237	29/18639	0.206896551724138	1.19133297114186	0.390511537392428	0.774611691335129
GO:0010484	histone H3 acetyltransferase activity	6/3237	29/18639	0.206896551724138	1.19133297114186	0.390511537392428	0.774611691335129
GO:0016417	S-acyltransferase activity	6/3237	29/18639	0.206896551724138	1.19133297114186	0.390511537392428	0.774611691335129
GO:0043236	laminin binding	6/3237	29/18639	0.206896551724138	1.19133297114186	0.390511537392428	0.774611691335129
GO:0097472	cyclin-dependent protein kinase activity	6/3237	29/18639	0.206896551724138	1.19133297114186	0.390511537392428	0.774611691335129
GO:0099604	ligand-gated calcium channel activity	6/3237	29/18639	0.206896551724138	1.19133297114186	0.390511537392428	0.774611691335129
GO:0004177	aminopeptidase activity	8/3237	40/18639	0.2	1.1516218721038	0.392058324581203	0.776520884304648
GO:0005035	death receptor activity	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0019855	calcium channel inhibitor activity	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0031432	titin binding	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0031994	insulin-like growth factor I binding	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0032396	inhibitory MHC class I receptor activity	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0046975	histone H3K36 methyltransferase activity	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0061459	L-arginine transmembrane transporter activity	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0071714	icosanoid transmembrane transporter activity	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0089720	caspase binding	3/3237	13/18639	0.230769230769231	1.32879446781208	0.398862777893589	0.778397403554448
GO:0004601	peroxidase activity	11/3237	57/18639	0.192982456140351	1.1112140871177	0.40263198251725	0.784601033380389
GO:0030276	clathrin binding	9/3237	46/18639	0.195652173913043	1.12658661401459	0.405263203288374	0.788572177408856
GO:0005154	epidermal growth factor receptor binding	7/3237	35/18639	0.2	1.1516218721038	0.407048288151955	0.790887682681211
GO:0045296	cadherin binding	60/3237	334/18639	0.179640718562874	1.03439090308725	0.408122310046437	0.791816861389364
GO:0001727	lipid kinase activity	8/3237	41/18639	0.195121951219512	1.1235335337598	0.420558684448984	0.8057555631919
GO:0008137	NADH dehydrogenase (ubiquinone) activity	8/3237	41/18639	0.195121951219512	1.1235335337598	0.420558684448984	0.8057555631919
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/3237	41/18639	0.195121951219512	1.1235335337598	0.420558684448984	0.8057555631919
GO:0140318	protein transporter activity	8/3237	41/18639	0.195121951219512	1.1235335337598	0.420558684448984	0.8057555631919
GO:0002039	p53 binding	13/3237	69/18639	0.188405797101449	1.0848611838659	0.421516318717271	0.8057555631919
GO:0001965	G-protein alpha-subunit binding	6/3237	30/18639	0.2	1.1516218721038	0.424009751757465	0.8057555631919
GO:0043995	histone H4K5 acetyltransferase activity	6/3237	30/18639	0.2	1.1516218721038	0.424009751757465	0.8057555631919
GO:0043996	histone H4K8 acetyltransferase activity	6/3237	30/18639	0.2	1.1516218721038	0.424009751757465	0.8057555631919
GO:0043997	histone H4K12 acetyltransferase activity	6/3237	30/18639	0.2	1.1516218721038	0.424009751757465	0.8057555631919
GO:0003756	protein disulfide isomerase activity	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0005520	insulin-like growth factor binding	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0042800	histone H3K4 methyltransferase activity	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0042834	peptidoglycan binding	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0046527	glucosyltransferase activity	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0097001	ceramide binding	4/3237	19/18639	0.210526315789474	1.21223354958295	0.425613548051703	0.8057555631919
GO:0005504	fatty acid binding	9/3237	47/18639	0.191489361702128	1.10261668605683	0.431957380558936	0.816602217301317
GO:0042626	ATPase-coupled transmembrane transporter activity	18/3237	98/18639	0.183673469387755	1.05761192336063	0.437704820080505	0.826292195862204
GO:0004864	protein phosphatase inhibitor activity	10/3237	53/18639	0.188679245283019	1.08643572839981	0.441808029161739	0.83035811503037
GO:0016860	intramolecular oxidoreductase activity	10/3237	53/18639	0.188679245283019	1.08643572839981	0.441808029161739	0.83035811503037
GO:0008081	phosphoric diester hydrolase activity	16/3237	87/18639	0.183908045977011	1.05896264101499	0.443880016544074	0.83035811503037
GO:0048487	beta-tubulin binding	8/3237	42/18639	0.19047619047619	1.09678273533695	0.448959751077155	0.83035811503037
GO:0005347	ATP transmembrane transporter activity	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0005545	1-phosphatidylinositol binding	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0008191	metalloendopeptidase inhibitor activity	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0015926	glucosidase activity	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0016530	metallochaperone activity	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0042813	Wnt receptor activity	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0046030	inositol trisphosphate phosphatase activity	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0070742	C2H2 zinc finger domain binding	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0071933	Arp2/3 complex binding	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:1990825	sequence-specific mRNA binding	3/3237	14/18639	0.214285714285714	1.23388057725407	0.448995528152516	0.83035811503037
GO:0015459	potassium channel regulator activity	11/3237	59/18639	0.186440677966102	1.07354581297812	0.450480211389689	0.83035811503037
GO:0036002	pre-mRNA binding	11/3237	59/18639	0.186440677966102	1.07354581297812	0.450480211389689	0.83035811503037
GO:0070888	E-box binding	11/3237	59/18639	0.186440677966102	1.07354581297812	0.450480211389689	0.83035811503037
GO:0120013	lipid transfer activity	12/3237	65/18639	0.184615384615385	1.06303557424966	0.458228166794559	0.843469852728488
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	22/3237	122/18639	0.180327868852459	1.03834758960179	0.459938036641029	0.845446266522722
GO:0015078	proton transmembrane transporter activity	33/3237	185/18639	0.178378378378378	1.02712221025474	0.462891125009823	0.849564270348354
GO:0016651	oxidoreductase activity, acting on NAD(P)H	16/3237	88/18639	0.181818181818182	1.04692897463982	0.463468244547404	0.849564270348354
GO:0031490	chromatin DNA binding	23/3237	128/18639	0.1796875	1.03466027571826	0.464772152108606	0.849564270348354
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	10/3237	54/18639	0.185185185185185	1.06631654824426	0.466880250264336	0.849564270348354
GO:0017069	snRNA binding	10/3237	54/18639	0.185185185185185	1.06631654824426	0.466880250264336	0.849564270348354
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	4/3237	20/18639	0.2	1.1516218721038	0.467292311229982	0.849564270348354
GO:0030742	GTP-dependent protein binding	4/3237	20/18639	0.2	1.1516218721038	0.467292311229982	0.849564270348354
GO:0140939	histone H4 methyltransferase activity	4/3237	20/18639	0.2	1.1516218721038	0.467292311229982	0.849564270348354
GO:0016410	N-acyltransferase activity	17/3237	94/18639	0.180851063829787	1.04136020349812	0.469189207463607	0.851023190453563
GO:0051087	protein-folding chaperone binding	24/3237	134/18639	0.17910447761194	1.03130316904818	0.469375469226833	0.851023190453563
GO:0046982	protein heterodimerization activity	65/3237	369/18639	0.176151761517615	1.01430110686649	0.471195865757431	0.853159816882325
GO:0048156	tau protein binding	8/3237	43/18639	0.186046511627907	1.07127616009656	0.477123493096301	0.859881014469526
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/3237	26/18639	0.192307692307692	1.10732872317673	0.480084057739946	0.859881014469526
GO:0008157	protein phosphatase 1 binding	5/3237	26/18639	0.192307692307692	1.10732872317673	0.480084057739946	0.859881014469526
GO:0015216	purine nucleotide transmembrane transporter activity	5/3237	26/18639	0.192307692307692	1.10732872317673	0.480084057739946	0.859881014469526
GO:0030507	spectrin binding	5/3237	26/18639	0.192307692307692	1.10732872317673	0.480084057739946	0.859881014469526
GO:0050750	low-density lipoprotein particle receptor binding	5/3237	26/18639	0.192307692307692	1.10732872317673	0.480084057739946	0.859881014469526
GO:0052742	phosphatidylinositol kinase activity	5/3237	26/18639	0.192307692307692	1.10732872317673	0.480084057739946	0.859881014469526
GO:0070006	metalloaminopeptidase activity	5/3237	26/18639	0.192307692307692	1.10732872317673	0.480084057739946	0.859881014469526
GO:0008235	metalloexopeptidase activity	12/3237	66/18639	0.181818181818182	1.04692897463982	0.480906777662604	0.860195299479947
GO:0017171	serine hydrolase activity	35/3237	198/18639	0.176767676767677	1.01784761423316	0.483416484557026	0.863522188140172
GO:0005200	structural constituent of cytoskeleton	20/3237	112/18639	0.178571428571429	1.02823381437839	0.484302513318664	0.863943678121483
GO:0022804	active transmembrane transporter activity	80/3237	457/18639	0.175054704595186	1.00798413313243	0.48816966776432	0.869674917505068
GO:0042910	xenobiotic transmembrane transporter activity	6/3237	32/18639	0.1875	1.07964550509731	0.48995777574245	0.870526582836518
GO:0140142	nucleocytoplasmic carrier activity	6/3237	32/18639	0.1875	1.07964550509731	0.48995777574245	0.870526582836518
GO:0000774	adenyl-nucleotide exchange factor activity	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0004467	long-chain fatty acid-CoA ligase activity	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0004953	icosanoid receptor activity	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0034483	heparan sulfate sulfotransferase activity	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0047372	monoacylglycerol lipase activity	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0120283	protein serine/threonine kinase binding	3/3237	15/18639	0.2	1.1516218721038	0.497327985554271	0.872065501448085
GO:0042162	telomeric DNA binding	7/3237	38/18639	0.184210526315789	1.06070435588508	0.498041922948906	0.872065501448085
GO:0042887	amide transmembrane transporter activity	7/3237	38/18639	0.184210526315789	1.06070435588508	0.498041922948906	0.872065501448085
GO:0030246	carbohydrate binding	49/3237	280/18639	0.175	1.00766913809082	0.501346047367283	0.876695917040947
GO:0003954	NADH dehydrogenase activity	8/3237	44/18639	0.181818181818182	1.04692897463982	0.504922281388816	0.881789371834082
GO:0016407	acetyltransferase activity	17/3237	96/18639	0.177083333333333	1.01966519925857	0.506843929554162	0.883353462524387
GO:0019200	carbohydrate kinase activity	4/3237	21/18639	0.19047619047619	1.09678273533695	0.507811922775494	0.883353462524387
GO:0061891	calcium ion sensor activity	4/3237	21/18639	0.19047619047619	1.09678273533695	0.507811922775494	0.883353462524387
GO:0004364	glutathione transferase activity	5/3237	27/18639	0.185185185185185	1.06631654824426	0.515644265339048	0.890499197630547
GO:0005044	scavenger receptor activity	5/3237	27/18639	0.185185185185185	1.06631654824426	0.515644265339048	0.890499197630547
GO:0016405	CoA-ligase activity	5/3237	27/18639	0.185185185185185	1.06631654824426	0.515644265339048	0.890499197630547
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/3237	27/18639	0.185185185185185	1.06631654824426	0.515644265339048	0.890499197630547
GO:0019956	chemokine binding	6/3237	33/18639	0.181818181818182	1.04692897463982	0.522012586247268	0.890499197630547
GO:0008237	metallopeptidase activity	32/3237	184/18639	0.173913043478261	1.00141032356852	0.527151810523287	0.890499197630547
GO:0140303	intramembrane lipid transporter activity	8/3237	45/18639	0.177777777777778	1.02366388631449	0.532239813651517	0.890499197630547
GO:0101005	deubiquitinase activity	20/3237	115/18639	0.173913043478261	1.00141032356852	0.535849520740762	0.890499197630547
GO:0016597	amino acid binding	9/3237	51/18639	0.176470588235294	1.01613694597394	0.536551654454778	0.890499197630547
GO:0030544	Hsp70 protein binding	9/3237	51/18639	0.176470588235294	1.01613694597394	0.536551654454778	0.890499197630547
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	15/3237	86/18639	0.174418604651163	1.00432140009052	0.537221262525651	0.890499197630547
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0005031	tumor necrosis factor receptor activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0005337	nucleoside transmembrane transporter activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0005381	iron ion transmembrane transporter activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0008519	ammonium channel activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0016868	intramolecular phosphotransferase activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0031419	cobalamin binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0032356	oxidized DNA binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0033204	ribonuclease P RNA binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0043208	glycosphingolipid binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0045322	unmethylated CpG binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0047429	nucleoside triphosphate diphosphatase activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0050815	phosphoserine residue binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0051880	G-quadruplex DNA binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0070513	death domain binding	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0140999	histone H3K4 trimethyltransferase activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0141109	transporter activator activity	2/3237	10/18639	0.2	1.1516218721038	0.539644868450621	0.890499197630547
GO:0000062	fatty-acyl-CoA binding	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0004707	MAP kinase activity	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0005024	transforming growth factor beta receptor activity	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0015385	sodium:proton antiporter activity	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0016722	oxidoreductase activity, acting on metal ions	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0017070	U6 snRNA binding	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0019841	retinol binding	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0030275	LRR domain binding	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0070411	I-SMAD binding	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/3237	16/18639	0.1875	1.07964550509731	0.543412226695541	0.890499197630547
GO:0005507	copper ion binding	11/3237	63/18639	0.174603174603175	1.00538417405887	0.54414210118927	0.890597108966182
GO:0016758	hexosyltransferase activity	34/3237	197/18639	0.17258883248731	0.993785371866223	0.545689502202157	0.892031178876588
GO:0015377	chloride:monoatomic cation symporter activity	4/3237	22/18639	0.181818181818182	1.04692897463982	0.546875907140033	0.892621760592877
GO:0016279	protein-lysine N-methyltransferase activity	12/3237	69/18639	0.173913043478261	1.00141032356852	0.547548318235626	0.892621760592877
GO:0036408	histone H3K14 acetyltransferase activity	5/3237	28/18639	0.178571428571429	1.02823381437839	0.550139849785742	0.892621760592877
GO:0046625	sphingolipid binding	5/3237	28/18639	0.178571428571429	1.02823381437839	0.550139849785742	0.892621760592877
GO:0050698	proteoglycan sulfotransferase activity	5/3237	28/18639	0.178571428571429	1.02823381437839	0.550139849785742	0.892621760592877
GO:0051015	actin filament binding	36/3237	209/18639	0.172248803827751	0.991827449658775	0.550524549306687	0.892621760592877
GO:0044183	protein folding chaperone	13/3237	75/18639	0.173333333333333	0.998072289156627	0.550752327830067	0.892621760592877
GO:0030971	receptor tyrosine kinase binding	14/3237	81/18639	0.172839506172839	0.995228778361308	0.553784180378884	0.895938053069642
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/3237	40/18639	0.175	1.00766913809082	0.556169220302825	0.895938053069642
GO:0061791	GTPase motor activity	7/3237	40/18639	0.175	1.00766913809082	0.556169220302825	0.895938053069642
GO:0140662	ATP-dependent protein folding chaperone	7/3237	40/18639	0.175	1.00766913809082	0.556169220302825	0.895938053069642
GO:1990606	membrane scission GTPase motor activity	7/3237	40/18639	0.175	1.00766913809082	0.556169220302825	0.895938053069642
GO:0051213	dioxygenase activity	16/3237	93/18639	0.172043010752688	0.990642470626925	0.559420575299536	0.900084678659907
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	10/3237	58/18639	0.172413793103448	0.992777475951552	0.564227767269873	0.906721526846023
GO:0031406	carboxylic acid binding	32/3237	187/18639	0.171122994652406	0.985344917308064	0.567162666964104	0.91033717922137
GO:0016278	lysine N-methyltransferase activity	12/3237	70/18639	0.171428571428571	0.987104461803257	0.569095430180465	0.912337547297755
GO:0015297	antiporter activity	23/3237	135/18639	0.17037037037037	0.981011224384718	0.576057074625235	0.915561278538314
GO:0008236	serine-type peptidase activity	33/3237	194/18639	0.170103092783505	0.979472210809933	0.582194391468233	0.915561278538314
GO:0004181	metallocarboxypeptidase activity	5/3237	29/18639	0.172413793103448	0.992777475951552	0.583395748201016	0.915561278538314
GO:0016829	lyase activity	34/3237	200/18639	0.17	0.97887859128823	0.584081929705944	0.915561278538314
GO:0004022	alcohol dehydrogenase (NAD+) activity	4/3237	23/18639	0.173913043478261	1.00141032356852	0.584252971623285	0.915561278538314
GO:0005158	insulin receptor binding	4/3237	23/18639	0.173913043478261	1.00141032356852	0.584252971623285	0.915561278538314
GO:0070577	lysine-acetylated histone binding	4/3237	23/18639	0.173913043478261	1.00141032356852	0.584252971623285	0.915561278538314
GO:0140938	histone H3 methyltransferase activity	8/3237	47/18639	0.170212765957447	0.980103720939404	0.585025957481939	0.915561278538314
GO:0005246	calcium channel regulator activity	9/3237	53/18639	0.169811320754717	0.97779215555983	0.586167478174396	0.915561278538314
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:0019198	transmembrane receptor protein phosphatase activity	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:0030548	acetylcholine receptor regulator activity	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:0036041	long-chain fatty acid binding	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:0048038	quinone binding	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:1901567	fatty acid derivative binding	3/3237	17/18639	0.176470588235294	1.01613694597394	0.586933855828364	0.915561278538314
GO:0043177	organic acid binding	32/3237	189/18639	0.169312169312169	0.97491798696618	0.593231648866487	0.915561278538314
GO:0000099	sulfur amino acid transmembrane transporter activity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0001851	complement component C3b binding	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0002162	dystroglycan binding	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0005536	D-glucose binding	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0015217	ADP transmembrane transporter activity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0034511	U3 snoRNA binding	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0035252	UDP-xylosyltransferase activity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0042285	xylosyltransferase activity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0043522	leucine zipper domain binding	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0047676	arachidonate-CoA ligase activity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0050786	RAGE receptor binding	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0097493	structural molecule activity conferring elasticity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:1990948	ubiquitin ligase inhibitor activity	2/3237	11/18639	0.181818181818182	1.04692897463982	0.593840347705061	0.915561278538314
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/3237	30/18639	0.166666666666667	0.959684893419833	0.615272947489726	0.942421763067089
GO:0008187	poly-pyrimidine tract binding	5/3237	30/18639	0.166666666666667	0.959684893419833	0.615272947489726	0.942421763067089
GO:0048019	receptor antagonist activity	5/3237	30/18639	0.166666666666667	0.959684893419833	0.615272947489726	0.942421763067089
GO:0004843	cysteine-type deubiquitinase activity	18/3237	108/18639	0.166666666666667	0.959684893419833	0.615921093377751	0.942421763067089
GO:0004806	triacylglycerol lipase activity	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0005315	phosphate transmembrane transporter activity	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0005540	hyaluronic acid binding	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0019957	C-C chemokine binding	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0048027	mRNA 5'-UTR binding	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0050431	transforming growth factor beta binding	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0140033	acetylation-dependent protein binding	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0140612	DNA damage sensor activity	4/3237	24/18639	0.166666666666667	0.959684893419833	0.619771723792804	0.942421763067089
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/3237	18/18639	0.166666666666667	0.959684893419833	0.627692399825178	0.944401251532551
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/3237	18/18639	0.166666666666667	0.959684893419833	0.627692399825178	0.944401251532551
GO:0017128	phospholipid scramblase activity	3/3237	18/18639	0.166666666666667	0.959684893419833	0.627692399825178	0.944401251532551
GO:0070628	proteasome binding	3/3237	18/18639	0.166666666666667	0.959684893419833	0.627692399825178	0.944401251532551
GO:0098641	cadherin binding involved in cell-cell adhesion	3/3237	18/18639	0.166666666666667	0.959684893419833	0.627692399825178	0.944401251532551
GO:0099602	neurotransmitter receptor regulator activity	3/3237	18/18639	0.166666666666667	0.959684893419833	0.627692399825178	0.944401251532551
GO:0016835	carbon-oxygen lyase activity	13/3237	79/18639	0.164556962025316	0.947536983376544	0.630885140770352	0.944401251532551
GO:0005253	monoatomic anion channel activity	17/3237	103/18639	0.16504854368932	0.950367564357505	0.631900352110947	0.944401251532551
GO:0098632	cell-cell adhesion mediator activity	9/3237	55/18639	0.163636363636364	0.942236077175836	0.633167072938614	0.944401251532551
GO:0008194	UDP-glycosyltransferase activity	24/3237	145/18639	0.16551724137931	0.953066376913489	0.6365803634846	0.944401251532551
GO:0004175	endopeptidase activity	68/3237	405/18639	0.167901234567901	0.966793670408128	0.642093294097981	0.944401251532551
GO:0004000	adenosine deaminase activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0004032	aldose reductase (NADPH) activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0004300	enoyl-CoA hydratase activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0004526	ribonuclease P activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0005025	transforming growth factor beta receptor activity, type I	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0005026	transforming growth factor beta receptor activity, type II	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0005078	MAP-kinase scaffold activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0015132	prostaglandin transmembrane transporter activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0016208	AMP binding	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0016361	activin receptor activity, type I	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0016362	activin receptor activity, type II	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0016801	hydrolase activity, acting on ether bonds	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0016803	ether hydrolase activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0017002	activin receptor activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0035251	UDP-glucosyltransferase activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0070410	co-SMAD binding	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0070679	inositol 1,4,5 trisphosphate binding	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0097371	MDM2/MDM4 family protein binding	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:1990459	transferrin receptor binding	2/3237	12/18639	0.166666666666667	0.959684893419833	0.643102432382963	0.944401251532551
GO:0008327	methyl-CpG binding	5/3237	31/18639	0.161290322580645	0.928727316212742	0.645666162526029	0.946075336270224
GO:0016878	acid-thiol ligase activity	5/3237	31/18639	0.161290322580645	0.928727316212742	0.645666162526029	0.946075336270224
GO:0048306	calcium-dependent protein binding	13/3237	80/18639	0.1625	0.935692771084337	0.649760122542417	0.950087891642324
GO:0008139	nuclear localization sequence binding	4/3237	25/18639	0.16	0.92129749768304	0.653314531566659	0.950087891642324
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/3237	25/18639	0.16	0.92129749768304	0.653314531566659	0.950087891642324
GO:0015645	fatty acid ligase activity	4/3237	25/18639	0.16	0.92129749768304	0.653314531566659	0.950087891642324
GO:0017056	structural constituent of nuclear pore	4/3237	25/18639	0.16	0.92129749768304	0.653314531566659	0.950087891642324
GO:0120515	fatty acid-CoA ligase activity	4/3237	25/18639	0.16	0.92129749768304	0.653314531566659	0.950087891642324
GO:0015179	L-amino acid transmembrane transporter activity	10/3237	62/18639	0.161290322580645	0.928727316212742	0.653408828413156	0.950087891642324
GO:0030170	pyridoxal phosphate binding	9/3237	56/18639	0.160714285714286	0.925410432940553	0.655544359687576	0.95111184937204
GO:0170055	lipid transmembrane transporter activity	9/3237	56/18639	0.160714285714286	0.925410432940553	0.655544359687576	0.95111184937204
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:0005229	intracellularly calcium-gated chloride channel activity	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:0016918	retinal binding	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:0043395	heparan sulfate proteoglycan binding	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:0070003	threonine-type peptidase activity	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:0120227	acyl-CoA binding	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:0141147	intracellularly calcium-gated channel activity	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:1990380	K48-linked deubiquitinase activity	3/3237	19/18639	0.157894736842105	0.90917516218721	0.665582184532705	0.957314635545416
GO:0008378	galactosyltransferase activity	5/3237	32/18639	0.15625	0.899704587581094	0.674501048967433	0.966633343738433
GO:0030515	snoRNA binding	5/3237	32/18639	0.15625	0.899704587581094	0.674501048967433	0.966633343738433
GO:0051059	NF-kappaB binding	5/3237	32/18639	0.15625	0.899704587581094	0.674501048967433	0.966633343738433
GO:0070279	vitamin B6 binding	9/3237	57/18639	0.157894736842105	0.90917516218721	0.677116250360164	0.966633343738433
GO:0005506	iron ion binding	25/3237	154/18639	0.162337662337662	0.934758013071266	0.677767303214132	0.966633343738433
GO:0001664	G protein-coupled receptor binding	49/3237	297/18639	0.164983164983165	0.949991106617613	0.678209010582576	0.966633343738433
GO:0005319	lipid transporter activity	29/3237	178/18639	0.162921348314607	0.938118940758713	0.678318025907693	0.966633343738433
GO:0005112	Notch binding	4/3237	26/18639	0.153846153846154	0.885862978541385	0.684810981353334	0.966633343738433
GO:0005227	calcium-activated cation channel activity	4/3237	26/18639	0.153846153846154	0.885862978541385	0.684810981353334	0.966633343738433
GO:0030247	polysaccharide binding	4/3237	26/18639	0.153846153846154	0.885862978541385	0.684810981353334	0.966633343738433
GO:0043548	phosphatidylinositol 3-kinase binding	4/3237	26/18639	0.153846153846154	0.885862978541385	0.684810981353334	0.966633343738433
GO:0003964	RNA-directed DNA polymerase activity	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0004465	lipoprotein lipase activity	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0008253	5'-nucleotidase activity	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0070123	transforming growth factor beta receptor activity, type III	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0071837	HMG box domain binding	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0140333	glycerophospholipid flippase activity	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:1901338	catecholamine binding	2/3237	13/18639	0.153846153846154	0.885862978541385	0.687509642290122	0.966633343738433
GO:0098631	cell adhesion mediator activity	12/3237	76/18639	0.157894736842105	0.90917516218721	0.688062560704708	0.966633343738433
GO:0004866	endopeptidase inhibitor activity	26/3237	161/18639	0.161490683229814	0.929881014742199	0.690502539175967	0.969036826362049
GO:0015291	secondary active transmembrane transporter activity	47/3237	287/18639	0.163763066202091	0.94296564440555	0.695925582249928	0.975617192837716
GO:0019239	deaminase activity	5/3237	33/18639	0.151515151515152	0.872440812199848	0.701731131596034	0.982610603484725
GO:0030159	signaling receptor complex adaptor activity	8/3237	52/18639	0.153846153846154	0.885862978541385	0.702762088115131	0.982610603484725
GO:0008135	translation factor activity, RNA binding	13/3237	83/18639	0.156626506024096	0.901872550442735	0.703132192561304	0.982610603484725
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/3237	46/18639	0.152173913043478	0.876234033122456	0.708948889951109	0.989698607925445
GO:0015252	proton channel activity	4/3237	27/18639	0.148148148148148	0.853053238595407	0.714231279790601	0.992430883211676
GO:0015036	disulfide oxidoreductase activity	6/3237	40/18639	0.15	0.86371640407785	0.716887469018568	0.992430883211676
GO:0180051	translation factor activity	13/3237	84/18639	0.154761904761905	0.891135972461274	0.719771161503352	0.992430883211676
GO:0019199	transmembrane receptor protein kinase activity	12/3237	78/18639	0.153846153846154	0.885862978541385	0.723011202327404	0.992430883211676
GO:0004252	serine-type endopeptidase activity	28/3237	176/18639	0.159090909090909	0.916062852809841	0.725497052765373	0.992430883211676
GO:0004705	JUN kinase activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0005313	L-glutamate transmembrane transporter activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0008174	mRNA methyltransferase activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0008195	phosphatidate phosphatase activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0008494	translation activator activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0008559	ABC-type xenobiotic transporter activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0015386	potassium:proton antiporter activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0019992	diacylglycerol binding	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0030983	mismatched DNA binding	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0031404	chloride ion binding	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0034236	protein kinase A catalytic subunit binding	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0043176	amine binding	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0098821	BMP receptor activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:1901474	azole transmembrane transporter activity	2/3237	14/18639	0.142857142857143	0.822587051502714	0.72726199464639	0.992430883211676
GO:0015035	protein-disulfide reductase activity	5/3237	34/18639	0.147058823529412	0.846780788311618	0.727334597628422	0.992430883211676
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	5/3237	34/18639	0.147058823529412	0.846780788311618	0.727334597628422	0.992430883211676
GO:0005123	death receptor binding	3/3237	21/18639	0.142857142857143	0.822587051502714	0.732701613838879	0.995665076474304
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/3237	21/18639	0.142857142857143	0.822587051502714	0.732701613838879	0.995665076474304
GO:0015125	bile acid transmembrane transporter activity	3/3237	21/18639	0.142857142857143	0.822587051502714	0.732701613838879	0.995665076474304
GO:0015174	basic amino acid transmembrane transporter activity	3/3237	21/18639	0.142857142857143	0.822587051502714	0.732701613838879	0.995665076474304
GO:0004714	transmembrane receptor protein tyrosine kinase activity	9/3237	60/18639	0.15	0.86371640407785	0.736721296620014	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/3237	41/18639	0.146341463414634	0.842650150319853	0.739652914591804	1
GO:0016866	intramolecular transferase activity	4/3237	28/18639	0.142857142857143	0.822587051502714	0.741579851458078	1
GO:0051959	dynein light intermediate chain binding	4/3237	28/18639	0.142857142857143	0.822587051502714	0.741579851458078	1
GO:0016209	antioxidant activity	13/3237	86/18639	0.151162790697674	0.870411880078453	0.751240982971612	1
GO:0016874	ligase activity	26/3237	167/18639	0.155688622754491	0.896472116008946	0.760499170955696	1
GO:0042056	chemoattractant activity	6/3237	42/18639	0.142857142857143	0.822587051502714	0.761075918091404	1
GO:0051879	Hsp90 protein binding	6/3237	42/18639	0.142857142857143	0.822587051502714	0.761075918091404	1
GO:0008970	phospholipase A1 activity	3/3237	22/18639	0.136363636363636	0.785196730979863	0.762042514896591	1
GO:0050321	tau-protein kinase activity	3/3237	22/18639	0.136363636363636	0.785196730979863	0.762042514896591	1
GO:0140517	protein-RNA adaptor activity	3/3237	22/18639	0.136363636363636	0.785196730979863	0.762042514896591	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0005523	tropomyosin binding	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0008252	nucleotidase activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0140161	monocarboxylate:sodium symporter activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0140776	protein-containing complex destabilizing activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0141050	histone H3K deacetylase activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0141051	histone H4K deacetylase activity	2/3237	15/18639	0.133333333333333	0.767747914735866	0.762636457583639	1
GO:0008509	monoatomic anion transmembrane transporter activity	23/3237	149/18639	0.154362416107383	0.888835673100248	0.764913010169344	1
GO:0005548	phospholipid transporter activity	10/3237	68/18639	0.147058823529412	0.846780788311618	0.765601044816221	1
GO:0003785	actin monomer binding	4/3237	29/18639	0.137931034482759	0.794221980761241	0.766889307979208	1
GO:0004629	phospholipase C activity	4/3237	29/18639	0.137931034482759	0.794221980761241	0.766889307979208	1
GO:0035250	UDP-galactosyltransferase activity	4/3237	29/18639	0.137931034482759	0.794221980761241	0.766889307979208	1
GO:0106222	lncRNA binding	4/3237	29/18639	0.137931034482759	0.794221980761241	0.766889307979208	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/3237	43/18639	0.13953488372093	0.803457120072418	0.781168967994169	1
GO:0030414	peptidase inhibitor activity	26/3237	169/18639	0.153846153846154	0.885862978541385	0.781397133870914	1
GO:1901682	sulfur compound transmembrane transporter activity	9/3237	63/18639	0.142857142857143	0.822587051502714	0.788393426096049	1
GO:0005283	amino acid:sodium symporter activity	3/3237	23/18639	0.130434782608696	0.751057742676391	0.788710946387587	1
GO:0140103	catalytic activity, acting on a glycoprotein	3/3237	23/18639	0.130434782608696	0.751057742676391	0.788710946387587	1
GO:0016769	transferase activity, transferring nitrogenous groups	4/3237	30/18639	0.133333333333333	0.767747914735866	0.790214901900666	1
GO:0022839	monoatomic ion-gated channel activity	4/3237	30/18639	0.133333333333333	0.767747914735866	0.790214901900666	1
GO:0031210	phosphatidylcholine binding	4/3237	30/18639	0.133333333333333	0.767747914735866	0.790214901900666	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/3237	16/18639	0.125	0.719763670064875	0.793954204853368	1
GO:0022858	alanine transmembrane transporter activity	2/3237	16/18639	0.125	0.719763670064875	0.793954204853368	1
GO:0140327	flippase activity	2/3237	16/18639	0.125	0.719763670064875	0.793954204853368	1
GO:0016830	carbon-carbon lyase activity	7/3237	51/18639	0.137254901960784	0.79032873575751	0.805983998806649	1
GO:0061980	regulatory RNA binding	8/3237	58/18639	0.137931034482759	0.794221980761241	0.812212216404679	1
GO:0030552	cAMP binding	3/3237	24/18639	0.125	0.719763670064875	0.812845121043984	1
GO:0015294	solute:monoatomic cation symporter activity	17/3237	116/18639	0.146551724137931	0.843860854558819	0.813657186506329	1
GO:0000146	microfilament motor activity	5/3237	38/18639	0.131578947368421	0.757645968489342	0.813731536366381	1
GO:0004222	metalloendopeptidase activity	16/3237	110/18639	0.145454545454545	0.837543179711854	0.817379013649094	1
GO:0019843	rRNA binding	9/3237	65/18639	0.138461538461538	0.797276680687246	0.818456732864667	1
GO:0008484	sulfuric ester hydrolase activity	2/3237	17/18639	0.117647058823529	0.677424630649294	0.821556918056702	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/3237	17/18639	0.117647058823529	0.677424630649294	0.821556918056702	1
GO:0045125	bioactive lipid receptor activity	2/3237	17/18639	0.117647058823529	0.677424630649294	0.821556918056702	1
GO:0070492	oligosaccharide binding	2/3237	17/18639	0.117647058823529	0.677424630649294	0.821556918056702	1
GO:0005080	protein kinase C binding	7/3237	52/18639	0.134615384615385	0.775130106223711	0.822040740469774	1
GO:0019838	growth factor binding	20/3237	136/18639	0.147058823529412	0.846780788311618	0.824647933146089	1
GO:0003823	antigen binding	26/3237	174/18639	0.149425287356322	0.860407145824678	0.828167810438663	1
GO:0005201	extracellular matrix structural constituent	25/3237	168/18639	0.148809523809524	0.856861511981994	0.830295552987159	1
GO:0015106	bicarbonate transmembrane transporter activity	4/3237	32/18639	0.125	0.719763670064875	0.831219312954559	1
GO:0001848	complement binding	3/3237	25/18639	0.12	0.69097312326228	0.834599292336347	1
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	8/3237	60/18639	0.133333333333333	0.767747914735866	0.840928044771181	1
GO:0003746	translation elongation factor activity	2/3237	18/18639	0.111111111111111	0.639789928946555	0.845789982835642	1
GO:0008525	phosphatidylcholine transporter activity	2/3237	18/18639	0.111111111111111	0.639789928946555	0.845789982835642	1
GO:0015172	acidic amino acid transmembrane transporter activity	2/3237	18/18639	0.111111111111111	0.639789928946555	0.845789982835642	1
GO:1990381	ubiquitin-specific protease binding	2/3237	18/18639	0.111111111111111	0.639789928946555	0.845789982835642	1
GO:0050997	quaternary ammonium group binding	5/3237	40/18639	0.125	0.719763670064875	0.847894437526182	1
GO:0048029	monosaccharide binding	10/3237	74/18639	0.135135135135135	0.778122886556622	0.849527081877794	1
GO:0003796	lysozyme activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0004935	adrenergic receptor activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0004955	prostaglandin receptor activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0005131	growth hormone receptor binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0005522	profilin binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0015187	glycine transmembrane transporter activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0015203	polyamine transmembrane transporter activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0015643	toxic substance binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0030957	Tat protein binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0031996	thioesterase binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0035374	chondroitin sulfate binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0042975	peroxisome proliferator activated receptor binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0043295	glutathione binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0051378	serotonin binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0051864	histone H3K36 demethylase activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0098505	G-rich strand telomeric DNA binding	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0140940	histone H2A methyltransferase activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/3237	10/18639	0.1	0.5758109360519	0.851637323033738	1
GO:0016836	hydro-lyase activity	8/3237	61/18639	0.131147540983607	0.755161883346754	0.853923634916033	1
GO:0015101	organic cation transmembrane transporter activity	11/3237	81/18639	0.135802469135802	0.781965468712457	0.853968064724908	1
GO:0001637	G protein-coupled chemoattractant receptor activity	3/3237	26/18639	0.115384615384615	0.664397233906038	0.85413689811674	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/3237	26/18639	0.115384615384615	0.664397233906038	0.85413689811674	1
GO:0004950	chemokine receptor activity	3/3237	26/18639	0.115384615384615	0.664397233906038	0.85413689811674	1
GO:0050681	nuclear androgen receptor binding	3/3237	26/18639	0.115384615384615	0.664397233906038	0.85413689811674	1
GO:0051139	metal cation:proton antiporter activity	3/3237	26/18639	0.115384615384615	0.664397233906038	0.85413689811674	1
GO:0097602	cullin family protein binding	3/3237	26/18639	0.115384615384615	0.664397233906038	0.85413689811674	1
GO:0015103	inorganic anion transmembrane transporter activity	24/3237	165/18639	0.145454545454545	0.837543179711854	0.85726038400327	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	6/3237	48/18639	0.125	0.719763670064875	0.862785748075452	1
GO:0004867	serine-type endopeptidase inhibitor activity	13/3237	95/18639	0.136842105263158	0.787951807228916	0.862787948993677	1
GO:0051082	unfolded protein binding	17/3237	121/18639	0.140495867768595	0.808990571312587	0.862807685009807	1
GO:0090482	vitamin transmembrane transporter activity	4/3237	34/18639	0.117647058823529	0.677424630649294	0.865312438980526	1
GO:0015245	fatty acid transmembrane transporter activity	2/3237	19/18639	0.105263157894737	0.606116774791474	0.866990900283047	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/3237	19/18639	0.105263157894737	0.606116774791474	0.866990900283047	1
GO:0022821	solute:potassium antiporter activity	2/3237	19/18639	0.105263157894737	0.606116774791474	0.866990900283047	1
GO:0042577	lipid phosphatase activity	2/3237	19/18639	0.105263157894737	0.606116774791474	0.866990900283047	1
GO:0008266	poly(U) RNA binding	3/3237	27/18639	0.111111111111111	0.639789928946555	0.871625100407507	1
GO:0008320	protein transmembrane transporter activity	3/3237	27/18639	0.111111111111111	0.639789928946555	0.871625100407507	1
GO:0008395	steroid hydroxylase activity	3/3237	27/18639	0.111111111111111	0.639789928946555	0.871625100407507	1
GO:0005254	chloride channel activity	11/3237	83/18639	0.132530120481928	0.763122927297699	0.874698570578345	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0004954	prostanoid receptor activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0008046	axon guidance receptor activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0008172	S-methyltransferase activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0008432	JUN kinase binding	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0008503	benzodiazepine receptor activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0008526	phosphatidylinositol transfer activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0016594	glycine binding	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0019107	myristoyltransferase activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0032404	mismatch repair complex binding	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0048407	platelet-derived growth factor binding	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0070697	activin receptor binding	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:1900750	oligopeptide binding	1/3237	11/18639	0.0909090909090909	0.523464487319909	0.877417020566605	1
GO:0005343	organic acid:sodium symporter activity	4/3237	35/18639	0.114285714285714	0.658069641202171	0.88002229240019	1
GO:0008083	growth factor activity	23/3237	162/18639	0.141975308641975	0.817509353653932	0.881753875365676	1
GO:0015095	magnesium ion transmembrane transporter activity	2/3237	20/18639	0.1	0.5758109360519	0.885481609746103	1
GO:0016408	C-acyltransferase activity	2/3237	20/18639	0.1	0.5758109360519	0.885481609746103	1
GO:0061608	nuclear import signal receptor activity	2/3237	20/18639	0.1	0.5758109360519	0.885481609746103	1
GO:0140664	ATP-dependent DNA damage sensor activity	2/3237	20/18639	0.1	0.5758109360519	0.885481609746103	1
GO:0141052	histone H3 demethylase activity	3/3237	28/18639	0.107142857142857	0.616940288627036	0.887230530281439	1
GO:0005006	epidermal growth factor receptor activity	6/3237	50/18639	0.12	0.69097312326228	0.887491102972407	1
GO:0005017	platelet-derived growth factor receptor activity	6/3237	50/18639	0.12	0.69097312326228	0.887491102972407	1
GO:0005019	platelet-derived growth factor beta-receptor activity	6/3237	50/18639	0.12	0.69097312326228	0.887491102972407	1
GO:0019842	vitamin binding	21/3237	150/18639	0.14	0.80613531047266	0.887527843459727	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/3237	36/18639	0.111111111111111	0.639789928946555	0.8933152678557	1
GO:0045505	dynein intermediate chain binding	4/3237	36/18639	0.111111111111111	0.639789928946555	0.8933152678557	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	4/3237	36/18639	0.111111111111111	0.639789928946555	0.8933152678557	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	4/3237	36/18639	0.111111111111111	0.639789928946555	0.8933152678557	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	4/3237	36/18639	0.111111111111111	0.639789928946555	0.8933152678557	1
GO:0005021	vascular endothelial growth factor receptor activity	6/3237	51/18639	0.117647058823529	0.677424630649294	0.898358716861174	1
GO:0000340	RNA 7-methylguanosine cap binding	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0003720	telomerase activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0003995	acyl-CoA dehydrogenase activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0004126	cytidine deaminase activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0004859	phospholipase inhibitor activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0005165	neurotrophin receptor binding	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0005436	sodium:phosphate symporter activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0015166	polyol transmembrane transporter activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0017166	vinculin binding	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0031543	peptidyl-proline dioxygenase activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0035197	siRNA binding	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0043047	single-stranded telomeric DNA binding	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:1990817	poly(A) RNA polymerase activity	1/3237	12/18639	0.0833333333333333	0.479842446709917	0.898718346765118	1
GO:0033293	monocarboxylic acid binding	10/3237	79/18639	0.126582278481013	0.728874602597342	0.899662298369157	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/3237	29/18639	0.103448275862069	0.595666485570931	0.901116055931696	1
GO:0001846	opsonin binding	2/3237	21/18639	0.0952380952380952	0.548391367668476	0.901563714578443	1
GO:0051428	peptide hormone receptor binding	2/3237	21/18639	0.0952380952380952	0.548391367668476	0.901563714578443	1
GO:0015293	symporter activity	20/3237	146/18639	0.136986301369863	0.788782104180685	0.903628374384464	1
GO:0030551	cyclic nucleotide binding	4/3237	37/18639	0.108108108108108	0.622498309245297	0.905296504474496	1
GO:0042805	actinin binding	4/3237	37/18639	0.108108108108108	0.622498309245297	0.905296504474496	1
GO:0070001	aspartic-type peptidase activity	4/3237	37/18639	0.108108108108108	0.622498309245297	0.905296504474496	1
GO:0000049	tRNA binding	10/3237	80/18639	0.125	0.719763670064875	0.907808923941495	1
GO:0032452	histone demethylase activity	3/3237	30/18639	0.1	0.5758109360519	0.913438406379588	1
GO:0016500	protein-hormone receptor activity	8/3237	67/18639	0.119402985074627	0.687535446032119	0.914936104560224	1
GO:0004407	histone deacetylase activity	2/3237	22/18639	0.0909090909090909	0.523464487319909	0.915515834546628	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/3237	22/18639	0.0909090909090909	0.523464487319909	0.915515834546628	1
GO:0033558	protein lysine deacetylase activity	2/3237	22/18639	0.0909090909090909	0.523464487319909	0.915515834546628	1
GO:0002161	aminoacyl-tRNA editing activity	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0004993	G protein-coupled serotonin receptor activity	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0005172	vascular endothelial growth factor receptor binding	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0008417	fucosyltransferase activity	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0009982	pseudouridine synthase activity	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0039706	co-receptor binding	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0045159	myosin II binding	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0070700	BMP receptor binding	1/3237	13/18639	0.0769230769230769	0.442931489270692	0.916319072138035	1
GO:0005003	ephrin receptor activity	6/3237	53/18639	0.113207547169811	0.651861437039887	0.917412254171606	1
GO:0005005	transmembrane-ephrin receptor activity	6/3237	53/18639	0.113207547169811	0.651861437039887	0.917412254171606	1
GO:0038064	collagen receptor activity	6/3237	53/18639	0.113207547169811	0.651861437039887	0.917412254171606	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/3237	46/18639	0.108695652173913	0.625881452230326	0.920550603324278	1
GO:0005452	solute:inorganic anion antiporter activity	3/3237	31/18639	0.0967741935483871	0.557236389727645	0.924346500282097	1
GO:0017147	Wnt-protein binding	3/3237	31/18639	0.0967741935483871	0.557236389727645	0.924346500282097	1
GO:0140457	protein demethylase activity	3/3237	31/18639	0.0967741935483871	0.557236389727645	0.924346500282097	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4/3237	39/18639	0.102564102564103	0.59057531902759	0.92573174362951	1
GO:0016493	C-C chemokine receptor activity	2/3237	23/18639	0.0869565217391304	0.500705161784261	0.927592490561774	1
GO:0016849	phosphorus-oxygen lyase activity	2/3237	23/18639	0.0869565217391304	0.500705161784261	0.927592490561774	1
GO:0017134	fibroblast growth factor binding	2/3237	23/18639	0.0869565217391304	0.500705161784261	0.927592490561774	1
GO:0031681	G-protein beta-subunit binding	2/3237	23/18639	0.0869565217391304	0.500705161784261	0.927592490561774	1
GO:0140359	ABC-type transporter activity	5/3237	47/18639	0.106382978723404	0.612564825587128	0.929088222479599	1
GO:0004065	arylsulfatase activity	1/3237	14/18639	0.0714285714285714	0.411293525751357	0.930861924252776	1
GO:0005344	oxygen carrier activity	1/3237	14/18639	0.0714285714285714	0.411293525751357	0.930861924252776	1
GO:0008331	high voltage-gated calcium channel activity	1/3237	14/18639	0.0714285714285714	0.411293525751357	0.930861924252776	1
GO:0042043	neurexin family protein binding	1/3237	14/18639	0.0714285714285714	0.411293525751357	0.930861924252776	1
GO:0061783	peptidoglycan muralytic activity	1/3237	14/18639	0.0714285714285714	0.411293525751357	0.930861924252776	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/3237	14/18639	0.0714285714285714	0.411293525751357	0.930861924252776	1
GO:0098847	sequence-specific single stranded DNA binding	1/3237	14/18639	0.0714285714285714	0.411293525751357	0.930861924252776	1
GO:0022884	macromolecule transmembrane transporter activity	3/3237	32/18639	0.09375	0.539822752548656	0.933980347247015	1
GO:0015144	carbohydrate transmembrane transporter activity	4/3237	40/18639	0.1	0.5758109360519	0.934380333196547	1
GO:0032451	demethylase activity	4/3237	40/18639	0.1	0.5758109360519	0.934380333196547	1
GO:0015149	hexose transmembrane transporter activity	2/3237	24/18639	0.0833333333333333	0.479842446709917	0.938024069608846	1
GO:0055056	D-glucose transmembrane transporter activity	2/3237	24/18639	0.0833333333333333	0.479842446709917	0.938024069608846	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/3237	24/18639	0.0833333333333333	0.479842446709917	0.938024069608846	1
GO:0004497	monooxygenase activity	13/3237	106/18639	0.122641509433962	0.706183223459877	0.941091224280513	1
GO:0004812	aminoacyl-tRNA ligase activity	4/3237	41/18639	0.0975609756097561	0.561766766879902	0.942104911663397	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	4/3237	41/18639	0.0975609756097561	0.561766766879902	0.942104911663397	1
GO:0140828	metal cation:monoatomic cation antiporter activity	4/3237	41/18639	0.0975609756097561	0.561766766879902	0.942104911663397	1
GO:0030296	protein tyrosine kinase activator activity	3/3237	33/18639	0.0909090909090909	0.523464487319909	0.942470406795454	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/3237	15/18639	0.0666666666666667	0.383873957367933	0.942878029014858	1
GO:0015116	sulfate transmembrane transporter activity	1/3237	15/18639	0.0666666666666667	0.383873957367933	0.942878029014858	1
GO:0031005	filamin binding	1/3237	15/18639	0.0666666666666667	0.383873957367933	0.942878029014858	1
GO:0051371	muscle alpha-actinin binding	1/3237	15/18639	0.0666666666666667	0.383873957367933	0.942878029014858	1
GO:0005004	GPI-linked ephrin receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0005008	hepatocyte growth factor receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0005009	insulin receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0005011	macrophage colony-stimulating factor receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0005020	stem cell factor receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0008288	boss receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0036332	placental growth factor receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0038062	protein tyrosine kinase collagen receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0060175	brain-derived neurotrophic factor receptor activity	5/3237	49/18639	0.102040816326531	0.587562179644796	0.943746136116117	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	24/3237	181/18639	0.132596685082873	0.76350621354948	0.945207096881494	1
GO:0015108	chloride transmembrane transporter activity	15/3237	121/18639	0.12396694214876	0.713815209981694	0.946771099544959	1
GO:0005251	delayed rectifier potassium channel activity	2/3237	25/18639	0.08	0.46064874884152	0.947017528502107	1
GO:0008483	transaminase activity	2/3237	25/18639	0.08	0.46064874884152	0.947017528502107	1
GO:0015271	outward rectifier potassium channel activity	2/3237	25/18639	0.08	0.46064874884152	0.947017528502107	1
GO:0016859	cis-trans isomerase activity	4/3237	42/18639	0.0952380952380952	0.548391367668476	0.948990505012243	1
GO:0035198	miRNA binding	4/3237	42/18639	0.0952380952380952	0.548391367668476	0.948990505012243	1
GO:0015020	glucuronosyltransferase activity	3/3237	34/18639	0.0882352941176471	0.508068472986971	0.949937306906576	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/3237	34/18639	0.0882352941176471	0.508068472986971	0.949937306906576	1
GO:0005007	fibroblast growth factor receptor activity	5/3237	50/18639	0.1	0.5758109360519	0.949996695354307	1
GO:0042562	hormone binding	11/3237	94/18639	0.117021276595745	0.67382130814584	0.950168541999486	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/3237	16/18639	0.0625	0.359881835032437	0.952806283958957	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/3237	16/18639	0.0625	0.359881835032437	0.952806283958957	1
GO:0015378	sodium:chloride symporter activity	1/3237	16/18639	0.0625	0.359881835032437	0.952806283958957	1
GO:0015562	efflux transmembrane transporter activity	1/3237	16/18639	0.0625	0.359881835032437	0.952806283958957	1
GO:0015145	monosaccharide transmembrane transporter activity	2/3237	26/18639	0.0769230769230769	0.442931489270692	0.954757581034221	1
GO:0120014	phospholipid transfer activity	2/3237	26/18639	0.0769230769230769	0.442931489270692	0.954757581034221	1
GO:0003743	translation initiation factor activity	5/3237	51/18639	0.0980392156862745	0.564520525541078	0.955609519103561	1
GO:0005010	insulin-like growth factor receptor activity	5/3237	51/18639	0.0980392156862745	0.564520525541078	0.955609519103561	1
GO:0005030	neurotrophin receptor activity	5/3237	51/18639	0.0980392156862745	0.564520525541078	0.955609519103561	1
GO:0005048	signal sequence binding	5/3237	51/18639	0.0980392156862745	0.564520525541078	0.955609519103561	1
GO:0046906	tetrapyrrole binding	19/3237	152/18639	0.125	0.719763670064875	0.959938016903275	1
GO:0009881	photoreceptor activity	1/3237	17/18639	0.0588235294117647	0.338712315324647	0.961009369327848	1
GO:0016805	dipeptidase activity	1/3237	17/18639	0.0588235294117647	0.338712315324647	0.961009369327848	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/3237	17/18639	0.0588235294117647	0.338712315324647	0.961009369327848	1
GO:0031489	myosin V binding	1/3237	17/18639	0.0588235294117647	0.338712315324647	0.961009369327848	1
GO:0045236	CXCR chemokine receptor binding	1/3237	17/18639	0.0588235294117647	0.338712315324647	0.961009369327848	1
GO:0005385	zinc ion transmembrane transporter activity	2/3237	27/18639	0.0740740740740741	0.426526619297704	0.961408179484358	1
GO:0004190	aspartic-type endopeptidase activity	3/3237	36/18639	0.0833333333333333	0.479842446709917	0.96223516421299	1
GO:0008146	sulfotransferase activity	5/3237	53/18639	0.0943396226415094	0.543217864199906	0.965144037015089	1
GO:0051018	protein kinase A binding	5/3237	53/18639	0.0943396226415094	0.543217864199906	0.965144037015089	1
GO:0015085	calcium ion transmembrane transporter activity	18/3237	147/18639	0.122448979591837	0.705074615573755	0.965165099355404	1
GO:0051119	sugar transmembrane transporter activity	2/3237	28/18639	0.0714285714285714	0.411293525751357	0.967114152499967	1
GO:0015373	monoatomic anion:sodium symporter activity	1/3237	18/18639	0.0555555555555556	0.319894964473278	0.967786980297978	1
GO:0008013	beta-catenin binding	12/3237	106/18639	0.113207547169811	0.651861437039887	0.967962538612663	1
GO:0008514	organic anion transmembrane transporter activity	36/3237	269/18639	0.133828996282528	0.770601996203286	0.968837088079142	1
GO:0020037	heme binding	17/3237	142/18639	0.119718309859155	0.689351120625514	0.970047289223128	1
GO:0005501	retinoid binding	3/3237	38/18639	0.0789473684210526	0.454587581093605	0.971646904453509	1
GO:0019840	isoprenoid binding	3/3237	38/18639	0.0789473684210526	0.454587581093605	0.971646904453509	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/3237	19/18639	0.0526315789473684	0.303058387395737	0.973386762521029	1
GO:0030506	ankyrin binding	1/3237	19/18639	0.0526315789473684	0.303058387395737	0.973386762521029	1
GO:0034987	immunoglobulin receptor binding	1/3237	19/18639	0.0526315789473684	0.303058387395737	0.973386762521029	1
GO:0046624	sphingolipid transporter activity	1/3237	19/18639	0.0526315789473684	0.303058387395737	0.973386762521029	1
GO:0099589	serotonin receptor activity	1/3237	19/18639	0.0526315789473684	0.303058387395737	0.973386762521029	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/3237	47/18639	0.0851063829787234	0.490051860469702	0.973423730723864	1
GO:0008201	heparin binding	21/3237	172/18639	0.122093023255814	0.703024980063366	0.975136473088992	1
GO:0033612	receptor serine/threonine kinase binding	2/3237	30/18639	0.0666666666666667	0.383873957367933	0.976186078537794	1
GO:0015171	amino acid transmembrane transporter activity	11/3237	102/18639	0.107843137254902	0.620972578095186	0.976372772137435	1
GO:0005262	calcium channel activity	15/3237	131/18639	0.114503816793893	0.659325499296069	0.976776856184792	1
GO:0000339	RNA cap binding	1/3237	20/18639	0.05	0.28790546802595	0.978013349509183	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/3237	20/18639	0.05	0.28790546802595	0.978013349509183	1
GO:0031418	L-ascorbic acid binding	1/3237	20/18639	0.05	0.28790546802595	0.978013349509183	1
GO:0005539	glycosaminoglycan binding	31/3237	242/18639	0.128099173553719	0.737609050314417	0.978819539929136	1
GO:0008227	G protein-coupled amine receptor activity	3/3237	41/18639	0.0731707317073171	0.421325075159927	0.981702396234155	1
GO:0005248	voltage-gated sodium channel activity	1/3237	21/18639	0.0476190476190476	0.274195683834238	0.98183583125572	1
GO:0036122	BMP binding	1/3237	21/18639	0.0476190476190476	0.274195683834238	0.98183583125572	1
GO:1904047	S-adenosyl-L-methionine binding	1/3237	21/18639	0.0476190476190476	0.274195683834238	0.98183583125572	1
GO:0008307	structural constituent of muscle	3/3237	42/18639	0.0714285714285714	0.411293525751357	0.984218695558918	1
GO:0031492	nucleosomal DNA binding	3/3237	42/18639	0.0714285714285714	0.411293525751357	0.984218695558918	1
GO:0016881	acid-amino acid ligase activity	1/3237	22/18639	0.0454545454545455	0.261732243659955	0.984993926337106	1
GO:0005245	voltage-gated calcium channel activity	3/3237	43/18639	0.0697674418604651	0.401728560036209	0.986401348774632	1
GO:0005212	structural constituent of eye lens	1/3237	23/18639	0.0434782608695652	0.25035258089213	0.987603082508712	1
GO:0016831	carboxy-lyase activity	2/3237	34/18639	0.0588235294117647	0.338712315324647	0.987633467403812	1
GO:0051427	hormone receptor binding	2/3237	34/18639	0.0588235294117647	0.338712315324647	0.987633467403812	1
GO:0017046	peptide hormone binding	4/3237	53/18639	0.0754716981132075	0.434574291359924	0.988275196984626	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/3237	44/18639	0.0681818181818182	0.392598365489932	0.988292375043186	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	6/3237	70/18639	0.0857142857142857	0.493552230901628	0.988393949272638	1
GO:0016782	transferase activity, transferring sulphur-containing groups	6/3237	70/18639	0.0857142857142857	0.493552230901628	0.988393949272638	1
GO:0015370	solute:sodium symporter activity	7/3237	79/18639	0.0886075949367089	0.510212221818139	0.989563944719265	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/3237	36/18639	0.0555555555555556	0.319894964473278	0.991125878471974	1
GO:0022829	wide pore channel activity	2/3237	37/18639	0.0540540540540541	0.311249154622649	0.992489690750276	1
GO:0031491	nucleosome binding	6/3237	74/18639	0.0810810810810811	0.466873731933973	0.992985604503938	1
GO:0008066	glutamate receptor activity	1/3237	26/18639	0.0384615384615385	0.221465744635346	0.993010853269203	1
GO:0034237	protein kinase A regulatory subunit binding	1/3237	26/18639	0.0384615384615385	0.221465744635346	0.993010853269203	1
GO:0046943	carboxylic acid transmembrane transporter activity	21/3237	188/18639	0.111702127659574	0.643193066866484	0.993181062911503	1
GO:0005342	organic acid transmembrane transporter activity	21/3237	189/18639	0.111111111111111	0.639789928946555	0.993741222004737	1
GO:0005104	fibroblast growth factor receptor binding	1/3237	27/18639	0.037037037037037	0.213263309648852	0.994226340722467	1
GO:0005242	inward rectifier potassium channel activity	1/3237	28/18639	0.0357142857142857	0.205646762875679	0.995230495841818	1
GO:0008527	taste receptor activity	1/3237	28/18639	0.0357142857142857	0.205646762875679	0.995230495841818	1
GO:0051393	alpha-actinin binding	1/3237	28/18639	0.0357142857142857	0.205646762875679	0.995230495841818	1
GO:0071855	neuropeptide receptor binding	2/3237	40/18639	0.05	0.28790546802595	0.995462921426113	1
GO:0005272	sodium channel activity	3/3237	51/18639	0.0588235294117647	0.338712315324647	0.99598405763771	1
GO:0003735	structural constituent of ribosome	18/3237	175/18639	0.102857142857143	0.592262677081954	0.996929951369013	1
GO:0005184	neuropeptide hormone activity	1/3237	31/18639	0.032258064516129	0.185745463242548	0.997311500293994	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/3237	31/18639	0.032258064516129	0.185745463242548	0.997311500293994	1
GO:0005179	hormone activity	12/3237	132/18639	0.0909090909090909	0.523464487319909	0.9976881556543	1
GO:0160041	neuropeptide activity	1/3237	32/18639	0.03125	0.179940917516219	0.997779184814004	1
GO:0042923	neuropeptide binding	1/3237	33/18639	0.0303030303030303	0.17448816243997	0.998165532895751	1
GO:1901681	sulfur compound binding	31/3237	275/18639	0.112727272727273	0.649095964276687	0.998168787127557	1
GO:0019825	oxygen binding	1/3237	34/18639	0.0294117647058824	0.169356157662324	0.998484686395506	1
GO:0099094	ligand-gated monoatomic cation channel activity	12/3237	136/18639	0.0882352941176471	0.508068472986971	0.99851750721774	1
GO:0015079	potassium ion transmembrane transporter activity	15/3237	160/18639	0.09375	0.539822752548656	0.998584483095966	1
GO:0008188	neuropeptide receptor activity	2/3237	48/18639	0.0416666666666667	0.239921223354958	0.998841369637973	1
GO:0015081	sodium ion transmembrane transporter activity	15/3237	164/18639	0.0914634146341463	0.526656343949908	0.999074083914738	1
GO:0030280	structural constituent of skin epidermis	1/3237	37/18639	0.027027027027027	0.155624577311324	0.999146013897723	1
GO:0022832	voltage-gated channel activity	16/3237	175/18639	0.0914285714285714	0.526455712961737	0.999340231344721	1
GO:0005244	voltage-gated monoatomic ion channel activity	15/3237	173/18639	0.0867052023121387	0.49925803703922	0.999653939812096	1
GO:0005267	potassium channel activity	9/3237	124/18639	0.0725806451612903	0.417927292295734	0.999688189410175	1
GO:0005249	voltage-gated potassium channel activity	6/3237	98/18639	0.0612244897959184	0.352537307786877	0.999729608818487	1
GO:0008528	G protein-coupled peptide receptor activity	8/3237	122/18639	0.0655737704918033	0.377580941673377	0.999874658281424	1
GO:0022843	voltage-gated monoatomic cation channel activity	10/3237	143/18639	0.0699300699300699	0.402664990246084	0.99991714382892	1
GO:0015276	ligand-gated monoatomic ion channel activity	15/3237	186/18639	0.0806451612903226	0.464363658106371	0.999921740010211	1
GO:0046873	metal ion transmembrane transporter activity	50/3237	450/18639	0.111111111111111	0.639789928946555	0.999927907706863	1
GO:0022834	ligand-gated channel activity	15/3237	188/18639	0.0797872340425532	0.459423619190346	0.999938128846039	1
GO:0001653	peptide receptor activity	8/3237	128/18639	0.0625	0.359881835032437	0.999944958139398	1
GO:0005216	monoatomic ion channel activity	49/3237	448/18639	0.109375	0.629793211306766	0.999952566624481	1
GO:0005261	monoatomic cation channel activity	33/3237	341/18639	0.0967741935483871	0.557236389727645	0.999981541210916	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/3237	73/18639	0.0273972602739726	0.157756420836137	0.999985724377965	1
GO:0022836	gated channel activity	28/3237	318/18639	0.0880503144654088	0.507003339919912	0.999996242017928	1
GO:0003730	mRNA 3'-UTR binding	21/3237	262/18639	0.0801526717557252	0.461527849507248	0.999996406453073	1
GO:0030594	neurotransmitter receptor activity	3/3237	97/18639	0.0309278350515464	0.178085856510897	0.999997994486184	1
GO:0030527	structural constituent of chromatin	2/3237	98/18639	0.0204081632653061	0.117512435928959	0.999999843405871	1
GO:0030371	translation repressor activity	9/3237	329/18639	0.027355623100304	0.15751666943669	1	1
GO:0045182	translation regulator activity	11/3237	356/18639	0.0308988764044944	0.177919109454239	1	1