ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0140097	catalytic activity, acting on DNA	160/4142	336/18639	0.476190476190476	2.14285714285714	3.60864365217077e-25	4.68401946051766e-22
GO:0008094	ATP-dependent activity, acting on DNA	113/4142	210/18639	0.538095238095238	2.42142857142857	1.30023488293196e-23	8.4385243902284e-21
GO:0004386	helicase activity	89/4142	155/18639	0.574193548387097	2.58387096774194	1.93906118798703e-21	8.38967140669054e-19
GO:0003697	single-stranded DNA binding	75/4142	121/18639	0.619834710743802	2.78925619834711	4.87136528830501e-21	1.58075803605498e-18
GO:0003712	transcription coregulator activity	190/4142	495/18639	0.383838383838384	1.72727272727273	1.37627177684812e-16	3.57280153269772e-14
GO:0003689	DNA clamp loader activity	81/4142	160/18639	0.50625	2.278125	2.65967274799899e-15	5.75375871150448e-13
GO:0016887	ATP hydrolysis activity	163/4142	417/18639	0.390887290167866	1.7589928057554	3.14081345293869e-15	5.8239655170206e-13
GO:0003678	DNA helicase activity	48/4142	74/18639	0.648648648648649	2.91891891891892	4.29029083131638e-15	6.96099687381082e-13
GO:0140658	ATP-dependent chromatin remodeler activity	79/4142	158/18639	0.5	2.25	1.41498518538087e-14	2.04072307847153e-12
GO:0140104	molecular carrier activity	109/4142	249/18639	0.437751004016064	1.96987951807229	2.18887432687467e-14	2.84115887628332e-12
GO:0061775	cohesin loader activity	76/4142	153/18639	0.496732026143791	2.23529411764706	6.95297251056934e-14	8.20450756247183e-12
GO:0015616	DNA translocase activity	75/4142	152/18639	0.493421052631579	2.22039473684211	1.57799252852748e-13	1.70686191835722e-11
GO:0140713	histone chaperone activity	79/4142	164/18639	0.481707317073171	2.16768292682927	1.84991735834562e-13	1.84707133164047e-11
GO:0017116	single-stranded DNA helicase activity	39/4142	58/18639	0.672413793103448	3.02586206896552	2.78589626533149e-13	2.56521089371163e-11
GO:0000510	H3-H4 histone complex chaperone activity	74/4142	151/18639	0.490066225165563	2.20529801324503	3.55730324243524e-13	2.56521089371163e-11
GO:0140584	chromatin extrusion motor activity	74/4142	151/18639	0.490066225165563	2.20529801324503	3.55730324243524e-13	2.56521089371163e-11
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	74/4142	151/18639	0.490066225165563	2.20529801324503	3.55730324243524e-13	2.56521089371163e-11
GO:0140849	ATP-dependent H2AZ histone chaperone activity	74/4142	151/18639	0.490066225165563	2.20529801324503	3.55730324243524e-13	2.56521089371163e-11
GO:0140674	ATP-dependent histone chaperone activity	74/4142	152/18639	0.486842105263158	2.19078947368421	5.43511084280919e-13	3.71303888103491e-11
GO:0140597	protein carrier chaperone	86/4142	188/18639	0.457446808510638	2.05851063829787	6.26311469500141e-13	4.06476143705592e-11
GO:0140098	catalytic activity, acting on RNA	147/4142	387/18639	0.37984496124031	1.7093023255814	1.02643668182067e-12	6.34435625239632e-11
GO:0042393	histone binding	104/4142	247/18639	0.421052631578947	1.89473684210526	1.68712764694461e-12	9.95405311697323e-11
GO:0004674	protein serine/threonine kinase activity	158/4142	433/18639	0.364896073903002	1.64203233256351	6.30550463171013e-12	3.55849783128685e-10
GO:0003725	double-stranded RNA binding	44/4142	75/18639	0.586666666666667	2.64	9.42744094694249e-12	5.09867431213807e-10
GO:0140297	DNA-binding transcription factor binding	173/4142	488/18639	0.354508196721311	1.5952868852459	1.02568448337528e-11	5.32535383768447e-10
GO:0106310	protein serine kinase activity	135/4142	361/18639	0.373961218836565	1.68282548476454	3.10370745567334e-11	1.54946626056308e-09
GO:0003688	DNA replication origin binding	16/4142	16/18639	1	4.5	3.45779068871532e-11	1.66230085701944e-09
GO:0030695	GTPase regulator activity	169/4142	489/18639	0.34560327198364	1.55521472392638	1.76571438233142e-10	8.18534738666496e-09
GO:0060589	nucleoside-triphosphatase regulator activity	169/4142	490/18639	0.344897959183673	1.55204081632653	2.11258482164146e-10	9.45563827065729e-09
GO:0015631	tubulin binding	139/4142	385/18639	0.361038961038961	1.62467532467532	2.71609408571921e-10	1.17516337442118e-08
GO:0044389	ubiquitin-like protein ligase binding	120/4142	322/18639	0.372670807453416	1.67701863354037	4.91754628192676e-10	2.0590242174003e-08
GO:0019787	ubiquitin-like protein transferase activity	164/4142	479/18639	0.342379958246347	1.54070981210856	7.26316840149565e-10	2.94612268285667e-08
GO:0003713	transcription coactivator activity	99/4142	256/18639	0.38671875	1.740234375	1.67147968069381e-09	6.57448674406233e-08
GO:0016755	aminoacyltransferase activity	167/4142	496/18639	0.336693548387097	1.51512096774194	2.06973032520751e-09	7.90149988858631e-08
GO:0043138	3'-5' DNA helicase activity	30/4142	48/18639	0.625	2.8125	2.26889398906334e-09	8.41435542229777e-08
GO:0031625	ubiquitin protein ligase binding	112/4142	302/18639	0.370860927152318	1.66887417218543	2.55027492419718e-09	9.19515792113318e-08
GO:0140030	modification-dependent protein binding	73/4142	173/18639	0.421965317919075	1.89884393063584	2.98735080131509e-09	1.04799495678567e-07
GO:0000217	DNA secondary structure binding	26/4142	39/18639	0.666666666666667	3	3.55489778397034e-09	1.21427824305092e-07
GO:1990518	single-stranded 3'-5' DNA helicase activity	29/4142	47/18639	0.617021276595745	2.77659574468085	6.45097494642679e-09	2.14701678986204e-07
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	124/4142	349/18639	0.355300859598854	1.59885386819484	7.46170789742784e-09	2.42132421271534e-07
GO:0009378	four-way junction helicase activity	29/4142	48/18639	0.604166666666667	2.71875	1.28341511445078e-08	3.9663638537074e-07
GO:0036121	double-stranded DNA helicase activity	29/4142	48/18639	0.604166666666667	2.71875	1.28341511445078e-08	3.9663638537074e-07
GO:0004842	ubiquitin-protein transferase activity	151/4142	449/18639	0.33630289532294	1.51336302895323	1.32966067602176e-08	4.01371990110755e-07
GO:0017056	structural constituent of nuclear pore	19/4142	25/18639	0.76	3.42	1.61771270853442e-08	4.77225249017655e-07
GO:0000287	magnesium ion binding	88/4142	230/18639	0.382608695652174	1.72173913043478	2.37552909492451e-08	6.7331907213758e-07
GO:0032182	ubiquitin-like protein binding	54/4142	120/18639	0.45	2.025	2.38618469324566e-08	6.7331907213758e-07
GO:0008017	microtubule binding	101/4142	276/18639	0.365942028985507	1.64673913043478	3.34180434649081e-08	9.22906817392568e-07
GO:0061749	forked DNA-dependent helicase activity	28/4142	47/18639	0.595744680851064	2.68085106382979	3.52978421984253e-08	9.54512482782418e-07
GO:0004677	DNA-dependent protein kinase activity	92/4142	246/18639	0.373983739837398	1.68292682926829	4.14023699786805e-08	1.07480552464654e-06
GO:0140857	histone H3T45 kinase activity	92/4142	246/18639	0.373983739837398	1.68292682926829	4.14023699786805e-08	1.07480552464654e-06
GO:0005096	GTPase activator activity	99/4142	271/18639	0.365313653136531	1.64391143911439	5.02088177551005e-08	1.27786363619844e-06
GO:0004676	3-phosphoinositide-dependent protein kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0004711	ribosomal protein S6 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0035175	histone H3S10 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0035979	histone H2AXS139 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0044022	histone H3S28 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0044023	histone H4S1 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0044024	histone H2AS1 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0044025	histone H2BS14 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0072354	histone H3T3 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0072371	histone H2AS121 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0072518	Rho-dependent protein serine/threonine kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0140823	histone H2BS36 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0140855	histone H3S57 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0140995	histone H2A kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0140997	histone H4 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0140998	histone H2B kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:1990244	histone H2AT120 kinase activity	91/4142	245/18639	0.371428571428571	1.67142857142857	7.09578585896165e-08	1.35446030072533e-06
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	90/4142	243/18639	0.37037037037037	1.66666666666667	9.72172545022006e-08	1.82881154121531e-06
GO:0035173	histone kinase activity	123/4142	360/18639	0.341666666666667	1.5375	1.08852608215209e-07	1.97667215366934e-06
GO:0035402	histone H3T11 kinase activity	91/4142	247/18639	0.368421052631579	1.65789473684211	1.09645912992444e-07	1.97667215366934e-06
GO:0035403	histone H3T6 kinase activity	91/4142	247/18639	0.368421052631579	1.65789473684211	1.09645912992444e-07	1.97667215366934e-06
GO:0004679	AMP-activated protein kinase activity	91/4142	248/18639	0.366935483870968	1.65120967741935	1.35819501609081e-07	2.41498237107654e-06
GO:0003714	transcription corepressor activity	78/4142	204/18639	0.382352941176471	1.72058823529412	1.50052072058051e-07	2.63199445312636e-06
GO:0016779	nucleotidyltransferase activity	57/4142	136/18639	0.419117647058824	1.88602941176471	2.03865645535557e-07	3.52823477206871e-06
GO:0141003	histone H2AX kinase activity	120/4142	354/18639	0.338983050847458	1.52542372881356	2.49740430687211e-07	4.26530367147369e-06
GO:0008186	ATP-dependent activity, acting on RNA	38/4142	79/18639	0.481012658227848	2.16455696202532	3.4309471570592e-07	5.78359663618551e-06
GO:0140996	histone H3 kinase activity	120/4142	357/18639	0.336134453781513	1.51260504201681	4.12953311735279e-07	6.87196664913323e-06
GO:0004518	nuclease activity	78/4142	209/18639	0.373205741626794	1.67942583732057	4.74424654864746e-07	7.79497724068912e-06
GO:0003684	damaged DNA binding	36/4142	74/18639	0.486486486486487	2.18918918918919	4.88909387165104e-07	7.93255480675381e-06
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	31/4142	60/18639	0.516666666666667	2.325	5.62691734440718e-07	9.0169613741241e-06
GO:0000400	four-way junction DNA binding	14/4142	18/18639	0.777777777777778	3.5	8.54049978507537e-07	1.35189862451559e-05
GO:0043130	ubiquitin binding	44/4142	100/18639	0.44	1.98	9.8715381637634e-07	1.5437658477789e-05
GO:0004715	non-membrane spanning protein tyrosine kinase activity	25/4142	45/18639	0.555555555555556	2.5	1.19734537364534e-06	1.85018368451386e-05
GO:0004532	RNA exonuclease activity	23/4142	40/18639	0.575	2.5875	1.41744208393864e-06	2.16451744112041e-05
GO:0003724	RNA helicase activity	36/4142	77/18639	0.467532467532468	2.1038961038961	1.63572677971509e-06	2.46880623263975e-05
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	22/4142	38/18639	0.578947368421053	2.60526315789474	2.05097086665163e-06	3.02518202831115e-05
GO:0042162	telomeric DNA binding	22/4142	38/18639	0.578947368421053	2.60526315789474	2.05097086665163e-06	3.02518202831115e-05
GO:0061733	protein-lysine-acetyltransferase activity	25/4142	47/18639	0.531914893617021	2.3936170212766	3.49007188723142e-06	5.09001495463638e-05
GO:0061659	ubiquitin-like protein ligase activity	120/4142	372/18639	0.32258064516129	1.45161290322581	4.24474065587352e-06	6.12185930147092e-05
GO:0004402	histone acetyltransferase activity	23/4142	42/18639	0.547619047619048	2.46428571428571	4.45230426079396e-06	6.35064937418742e-05
GO:0070034	telomerase RNA binding	15/4142	22/18639	0.681818181818182	3.06818181818182	5.24297703545136e-06	7.39715673045203e-05
GO:0140142	nucleocytoplasmic carrier activity	19/4142	32/18639	0.59375	2.671875	6.14468296076423e-06	8.57612740115266e-05
GO:0004527	exonuclease activity	37/4142	84/18639	0.44047619047619	1.98214285714286	6.78904857487038e-06	9.37466494700186e-05
GO:0001098	basal transcription machinery binding	29/4142	60/18639	0.483333333333333	2.175	7.30037690839188e-06	9.87071794488819e-05
GO:0001099	basal RNA polymerase II transcription machinery binding	29/4142	60/18639	0.483333333333333	2.175	7.30037690839188e-06	9.87071794488819e-05
GO:0002039	p53 binding	32/4142	69/18639	0.463768115942029	2.08695652173913	7.54544629744514e-06	0.000100968961794678
GO:0000175	3'-5'-RNA exonuclease activity	20/4142	35/18639	0.571428571428571	2.57142857142857	7.88537089885911e-06	0.000103385974007264
GO:0010485	histone H4 acetyltransferase activity	20/4142	35/18639	0.571428571428571	2.57142857142857	7.88537089885911e-06	0.000103385974007264
GO:0061630	ubiquitin protein ligase activity	113/4142	353/18639	0.320113314447592	1.44050991501416	1.17694835635133e-05	0.000152767896654403
GO:0001221	transcription coregulator binding	46/4142	115/18639	0.4	1.8	1.30127111975386e-05	0.000167232664697081
GO:0034212	protein N-acetyltransferase activity	26/4142	53/18639	0.490566037735849	2.20754716981132	1.53551224276443e-05	0.000195401459912572
GO:0140789	histone phosphatase activity	52/4142	136/18639	0.382352941176471	1.72058823529412	1.6704311780838e-05	0.000210506763995415
GO:0004721	phosphoprotein phosphatase activity	63/4142	175/18639	0.36	1.62	2.15573743944325e-05	0.000269052615038206
GO:0031267	small GTPase binding	93/4142	283/18639	0.328621908127208	1.47879858657244	2.18687178336018e-05	0.000270339007123953
GO:0140033	acetylation-dependent protein binding	15/4142	24/18639	0.625	2.8125	2.53365894339695e-05	0.000310253708351815
GO:0004540	RNA nuclease activity	47/4142	121/18639	0.388429752066116	1.74793388429752	2.60045640963533e-05	0.000315457235486603
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	49/4142	128/18639	0.3828125	1.72265625	2.78198724588087e-05	0.000334353652329015
GO:0030515	snoRNA binding	18/4142	32/18639	0.5625	2.53125	3.01521387319099e-05	0.000359059413523111
GO:0043021	ribonucleoprotein complex binding	63/4142	177/18639	0.355932203389831	1.60169491525424	3.21705116350529e-05	0.000379612037293624
GO:0001222	transcription corepressor binding	24/4142	49/18639	0.489795918367347	2.20408163265306	3.35052253934719e-05	0.000391799842889428
GO:0008408	3'-5' exonuclease activity	27/4142	58/18639	0.46551724137931	2.0948275862069	3.5116619949752e-05	0.000406976541917662
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	60/4142	167/18639	0.359281437125749	1.61676646706587	3.57667544807724e-05	0.000410842896602147
GO:0140852	histone ubiquitin ligase activity	10/4142	13/18639	0.769230769230769	3.46153846153846	4.2447031799528e-05	0.000483300414699889
GO:0031491	nucleosome binding	32/4142	74/18639	0.432432432432432	1.94594594594595	4.34908236415169e-05	0.000490879035536426
GO:0016791	phosphatase activity	89/4142	273/18639	0.326007326007326	1.46703296703297	4.52897069074167e-05	0.000506776203153681
GO:0070063	RNA polymerase binding	27/4142	59/18639	0.457627118644068	2.0593220338983	5.11187292169618e-05	0.000567112055757405
GO:0051020	GTPase binding	100/4142	315/18639	0.317460317460317	1.42857142857143	5.25327565010475e-05	0.000577860321511522
GO:0031072	heat shock protein binding	49/4142	131/18639	0.374045801526718	1.68320610687023	5.59594980363155e-05	0.000610381751690232
GO:0070577	lysine-acetylated histone binding	14/4142	23/18639	0.608695652173913	2.73913043478261	7.22650710114038e-05	0.000781667184773351
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	23/4142	48/18639	0.479166666666667	2.15625	7.52144521843629e-05	0.000806845941614075
GO:0140463	chromatin-protein adaptor activity	25/4142	54/18639	0.462962962962963	2.08333333333333	7.58995867382671e-05	0.00080752183267435
GO:0016407	acetyltransferase activity	38/4142	96/18639	0.395833333333333	1.78125	9.27046141956365e-05	0.000978297473381594
GO:0010484	histone H3 acetyltransferase activity	16/4142	29/18639	0.551724137931034	2.48275862068965	0.000114471671677332	0.00119825991804175
GO:0043998	histone H2A acetyltransferase activity	14/4142	24/18639	0.583333333333333	2.625	0.000137964945219812	0.00143262799116252
GO:0140566	histone reader activity	18/4142	35/18639	0.514285714285714	2.31428571428571	0.000144611403934057	0.00148972700243179
GO:0005049	nuclear export signal receptor activity	9/4142	12/18639	0.75	3.375	0.000148321932274521	0.00150407709447131
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	9/4142	12/18639	0.75	3.375	0.000148321932274521	0.00150407709447131
GO:0001046	core promoter sequence-specific DNA binding	21/4142	44/18639	0.477272727272727	2.14772727272727	0.000164417824369183	0.00165142910407252
GO:0140938	histone H3 methyltransferase activity	22/4142	47/18639	0.468085106382979	2.1063829787234	0.000165397367896323	0.00165142910407252
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	8/4142	10/18639	0.8	3.6	0.000171683205463531	0.00168821818705806
GO:0098505	G-rich strand telomeric DNA binding	8/4142	10/18639	0.8	3.6	0.000171683205463531	0.00168821818705806
GO:0019902	phosphatase binding	64/4142	190/18639	0.336842105263158	1.51578947368421	0.000179488677518661	0.00175170152946784
GO:0043995	histone H4K5 acetyltransferase activity	16/4142	30/18639	0.533333333333333	2.4	0.000194828757115833	0.00185946857894376
GO:0043996	histone H4K8 acetyltransferase activity	16/4142	30/18639	0.533333333333333	2.4	0.000194828757115833	0.00185946857894376
GO:0043997	histone H4K12 acetyltransferase activity	16/4142	30/18639	0.533333333333333	2.4	0.000194828757115833	0.00185946857894376
GO:0016922	nuclear receptor binding	49/4142	137/18639	0.357664233576642	1.60948905109489	0.000201265666242347	0.00190688200571216
GO:0004722	protein serine/threonine phosphatase activity	39/4142	103/18639	0.378640776699029	1.70388349514563	0.000228794864223806	0.002129321478974
GO:0000993	RNA polymerase II complex binding	18/4142	36/18639	0.5	2.25	0.00022941918207791	0.002129321478974
GO:0017069	snRNA binding	24/4142	54/18639	0.444444444444444	2	0.000229664874465609	0.002129321478974
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	33/4142	83/18639	0.397590361445783	1.78915662650602	0.000236656107568759	0.00217857891932092
GO:0043175	RNA polymerase core enzyme binding	20/4142	42/18639	0.476190476190476	2.14285714285714	0.00024336349351932	0.00222454799005688
GO:0042054	histone methyltransferase activity	28/4142	67/18639	0.417910447761194	1.88059701492537	0.000258383409230125	0.00234532632993498
GO:0036408	histone H3K14 acetyltransferase activity	15/4142	28/18639	0.535714285714286	2.41071428571429	0.000289402405700938	0.00259679150145197
GO:0016741	transferase activity, transferring one-carbon groups	70/4142	215/18639	0.325581395348837	1.46511627906977	0.000290088418883309	0.00259679150145197
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	12/4142	20/18639	0.6	2.7	0.000292194963824678	0.00259773330852351
GO:0005085	guanyl-nucleotide exchange factor activity	74/4142	230/18639	0.321739130434783	1.44782608695652	0.000296741482287919	0.00262020710210693
GO:0044013	histone H2B acetyltransferase activity	13/4142	23/18639	0.565217391304348	2.54347826086956	0.000368479374296394	0.00323166370159946
GO:0008276	protein methyltransferase activity	36/4142	95/18639	0.378947368421053	1.70526315789474	0.000383996139571279	0.00334486343286361
GO:0004535	poly(A)-specific ribonuclease activity	9/4142	13/18639	0.692307692307692	3.11538461538462	0.000386540458343253	0.00334486343286361
GO:0070628	proteasome binding	11/4142	18/18639	0.611111111111111	2.75	0.000422985746783137	0.00363599668426829
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	32/4142	82/18639	0.390243902439024	1.75609756097561	0.000433282072602374	0.00370000085682817
GO:0008080	N-acetyltransferase activity	28/4142	69/18639	0.405797101449275	1.82608695652174	0.000461466090818998	0.00391492147635986
GO:0140296	general transcription initiation factor binding	23/4142	53/18639	0.433962264150943	1.95283018867925	0.000469693189596193	0.00395884259802506
GO:0032404	mismatch repair complex binding	8/4142	11/18639	0.727272727272727	3.27272727272727	0.00050611071513876	0.00421110069391096
GO:0034511	U3 snoRNA binding	8/4142	11/18639	0.727272727272727	3.27272727272727	0.00050611071513876	0.00421110069391096
GO:0008168	methyltransferase activity	66/4142	204/18639	0.323529411764706	1.45588235294118	0.000515575595026886	0.00426252944168725
GO:0043015	gamma-tubulin binding	17/4142	35/18639	0.485714285714286	2.18571428571429	0.000527099623228172	0.00433022348702637
GO:0017124	SH3 domain binding	41/4142	115/18639	0.356521739130435	1.60434782608696	0.000688288958312036	0.00561886206219511
GO:0033192	calmodulin-dependent protein phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:0140791	histone H2AXS140 phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:1990439	MAP kinase serine/threonine phosphatase activity	31/4142	81/18639	0.382716049382716	1.72222222222222	0.000779649691483665	0.00605979221284909
GO:0140036	ubiquitin-modified protein reader activity	11/4142	19/18639	0.578947368421053	2.60526315789474	0.000803121805098633	0.00620507204177396
GO:0004197	cysteine-type endopeptidase activity	33/4142	88/18639	0.375	1.6875	0.000815907759063063	0.00626655781812932
GO:0019207	kinase regulator activity	87/4142	287/18639	0.303135888501742	1.36411149825784	0.000823407730448552	0.00628696020071894
GO:0051087	protein-folding chaperone binding	46/4142	134/18639	0.343283582089552	1.54477611940299	0.000865366479192107	0.00655395266795984
GO:0098847	sequence-specific single stranded DNA binding	9/4142	14/18639	0.642857142857143	2.89285714285714	0.000868474467557083	0.00655395266795984
GO:0032931	histone H3K56 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0034062	5'-3' RNA polymerase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0043992	histone H3K9 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0043993	histone H3K18 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0043994	histone H3K23 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0043999	histone H2AK5 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0044012	histone H2AK9 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0044014	histone H2BK5 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0044015	histone H2BK12 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0044016	histone H3K4 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0044017	histone H3K27 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0044018	histone H3K36 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0046972	histone H4K16 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0061133	endopeptidase activator activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0097747	RNA polymerase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0140035	ubiquitin-like protein reader activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0140908	histone H3K122 acetyltransferase activity	12/4142	22/18639	0.545454545454545	2.45454545454545	0.000955765782886407	0.00656393643484951
GO:0033549	MAP kinase phosphatase activity	31/4142	82/18639	0.378048780487805	1.70121951219512	0.000990186871587984	0.00676453978590107
GO:0019887	protein kinase regulator activity	78/4142	255/18639	0.305882352941176	1.37647058823529	0.00111902787146332	0.00760470249821671
GO:0032183	SUMO binding	10/4142	17/18639	0.588235294117647	2.64705882352941	0.00118436184035019	0.0080067795248674
GO:0043047	single-stranded telomeric DNA binding	8/4142	12/18639	0.666666666666667	3	0.00122168828086724	0.00821632843816411
GO:0043539	protein serine/threonine kinase activator activity	28/4142	73/18639	0.383561643835616	1.72602739726027	0.00131645241324138	0.00880801666179026
GO:0019903	protein phosphatase binding	48/4142	144/18639	0.333333333333333	1.5	0.00139029643960018	0.00925438348000532
GO:0019205	nucleobase-containing compound kinase activity	19/4142	44/18639	0.431818181818182	1.94318181818182	0.00153406897732558	0.0101592935335133
GO:0042578	phosphoric ester hydrolase activity	105/4142	363/18639	0.289256198347107	1.30165289256198	0.00154990844606423	0.0102120871217836
GO:0017018	myosin phosphatase activity	31/4142	84/18639	0.369047619047619	1.66071428571429	0.00156371387393384	0.0102510131735663
GO:0061650	ubiquitin-like protein conjugating enzyme activity	18/4142	41/18639	0.439024390243902	1.97560975609756	0.00161166884678305	0.010512292277007
GO:0019783	ubiquitin-like protein peptidase activity	43/4142	127/18639	0.338582677165354	1.52362204724409	0.00170275479787385	0.0110508786382013
GO:0061631	ubiquitin conjugating enzyme activity	16/4142	35/18639	0.457142857142857	2.05714285714286	0.00172804354446846	0.0111592065707466
GO:0051059	NF-kappaB binding	15/4142	32/18639	0.46875	2.109375	0.0017542514598749	0.0112723682916714
GO:0030145	manganese ion binding	26/4142	68/18639	0.382352941176471	1.72058823529412	0.00202963184011111	0.0129776459530257
GO:0051539	4 iron, 4 sulfur cluster binding	19/4142	45/18639	0.422222222222222	1.9	0.00210849322362555	0.0134158049228724
GO:0004706	JUN kinase kinase kinase activity	10/4142	18/18639	0.555555555555556	2.5	0.002136081957309	0.0135250457589614
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	32/4142	89/18639	0.359550561797753	1.61797752808989	0.00216436527656646	0.0135717204298709
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	32/4142	89/18639	0.359550561797753	1.61797752808989	0.00216436527656646	0.0135717204298709
GO:0070182	DNA polymerase binding	11/4142	21/18639	0.523809523809524	2.35714285714286	0.00239941945275111	0.0149733002388026
GO:0140612	DNA damage sensor activity	12/4142	24/18639	0.5	2.25	0.00255197821221868	0.0157612379255559
GO:0046975	histone H3K36 methyltransferase activity	8/4142	13/18639	0.615384615384615	2.76923076923077	0.00255792479690561	0.0157612379255559
GO:0071889	14-3-3 protein binding	15/4142	33/18639	0.454545454545455	2.04545454545454	0.00256211186617281	0.0157612379255559
GO:0016763	pentosyltransferase activity	20/4142	49/18639	0.408163265306122	1.83673469387755	0.00264547300238217	0.0160989357436867
GO:0140034	methylation-dependent protein binding	28/4142	76/18639	0.368421052631579	1.65789473684211	0.00264849729459961	0.0160989357436867
GO:0140793	histone H2AXY142 phosphatase activity	32/4142	90/18639	0.355555555555556	1.6	0.00265421590843525	0.0160989357436867
GO:0031593	polyubiquitin modification-dependent protein binding	23/4142	59/18639	0.389830508474576	1.75423728813559	0.00268560356298884	0.0161384880775903
GO:0045309	protein phosphorylated amino acid binding	23/4142	59/18639	0.389830508474576	1.75423728813559	0.00268560356298884	0.0161384880775903
GO:0048156	tau protein binding	18/4142	43/18639	0.418604651162791	1.88372093023256	0.00306456061363767	0.0183308740852613
GO:0004519	endonuclease activity	42/4142	127/18639	0.330708661417323	1.48818897637795	0.00314279824975224	0.0187016975455584
GO:0004725	protein tyrosine phosphatase activity	34/4142	98/18639	0.346938775510204	1.56122448979592	0.00315537115753258	0.0187016975455584
GO:0008234	cysteine-type peptidase activity	58/4142	187/18639	0.310160427807487	1.39572192513369	0.00320555100329178	0.0189127509194215
GO:0051540	metal cluster binding	28/4142	77/18639	0.363636363636364	1.63636363636364	0.00329353809494256	0.0193439477250473
GO:0052866	phosphatidylinositol phosphate phosphatase activity	15/4142	34/18639	0.441176470588235	1.98529411764706	0.0036540102270637	0.0212850666786804
GO:0035064	methylated histone binding	27/4142	74/18639	0.364864864864865	1.64189189189189	0.00365683348948053	0.0212850666786804
GO:0019208	phosphatase regulator activity	39/4142	117/18639	0.333333333333333	1.5	0.0037019173396246	0.021451288869789
GO:0032794	GTPase activating protein binding	7/4142	11/18639	0.636363636363636	2.86363636363636	0.00372975736432621	0.021516555817313
GO:0001784	phosphotyrosine residue binding	19/4142	47/18639	0.404255319148936	1.81914893617021	0.00380621467240492	0.02178300835439
GO:0004407	histone deacetylase activity	11/4142	22/18639	0.5	2.25	0.00384307312261579	0.02178300835439
GO:0033558	protein lysine deacetylase activity	11/4142	22/18639	0.5	2.25	0.00384307312261579	0.02178300835439
GO:0050321	tau-protein kinase activity	11/4142	22/18639	0.5	2.25	0.00384307312261579	0.02178300835439
GO:0004709	MAP kinase kinase kinase activity	12/4142	25/18639	0.48	2.16	0.00392466217574044	0.0218635686871721
GO:0008139	nuclear localization sequence binding	12/4142	25/18639	0.48	2.16	0.00392466217574044	0.0218635686871721
GO:0017025	TBP-class protein binding	12/4142	25/18639	0.48	2.16	0.00392466217574044	0.0218635686871721
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	12/4142	25/18639	0.48	2.16	0.00392466217574044	0.0218635686871721
GO:0004536	DNA nuclease activity	24/4142	64/18639	0.375	1.6875	0.0039767435284249	0.0220590303414339
GO:0005525	GTP binding	106/4142	378/18639	0.28042328042328	1.26190476190476	0.00431408127414752	0.0238284148674191
GO:0003727	single-stranded RNA binding	31/4142	89/18639	0.348314606741573	1.56741573033708	0.00437471050185626	0.0240609077602094
GO:0051219	phosphoprotein binding	32/4142	93/18639	0.344086021505376	1.54838709677419	0.00472876434015098	0.0258984646139915
GO:0008474	palmitoyl-(protein) hydrolase activity	8/4142	14/18639	0.571428571428571	2.57142857142857	0.00481052523603698	0.0259089699434689
GO:0030983	mismatched DNA binding	8/4142	14/18639	0.571428571428571	2.57142857142857	0.00481052523603698	0.0259089699434689
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	8/4142	14/18639	0.571428571428571	2.57142857142857	0.00481052523603698	0.0259089699434689
GO:0098599	palmitoyl hydrolase activity	8/4142	14/18639	0.571428571428571	2.57142857142857	0.00481052523603698	0.0259089699434689
GO:0043022	ribosome binding	37/4142	112/18639	0.330357142857143	1.48660714285714	0.00544025652869586	0.0291119791089891
GO:0004659	prenyltransferase activity	9/4142	17/18639	0.529411764705882	2.38235294117647	0.00547251379244478	0.0291119791089891
GO:1990226	histone methyltransferase binding	9/4142	17/18639	0.529411764705882	2.38235294117647	0.00547251379244478	0.0291119791089891
GO:0051536	iron-sulfur cluster binding	27/4142	76/18639	0.355263157894737	1.59868421052632	0.00555831318202762	0.0294477163684565
GO:0016279	protein-lysine N-methyltransferase activity	25/4142	69/18639	0.36231884057971	1.6304347826087	0.00560005017186214	0.0295482322076303
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	13/4142	29/18639	0.448275862068966	2.01724137931035	0.00564978329777338	0.0295571121726226
GO:0097472	cyclin-dependent protein kinase activity	13/4142	29/18639	0.448275862068966	2.01724137931035	0.00564978329777338	0.0295571121726226
GO:0016410	N-acyltransferase activity	32/4142	94/18639	0.340425531914894	1.53191489361702	0.00567004694220572	0.0295571121726226
GO:0061608	nuclear import signal receptor activity	10/4142	20/18639	0.5	2.25	0.00580670964176312	0.0300283231673646
GO:0140664	ATP-dependent DNA damage sensor activity	10/4142	20/18639	0.5	2.25	0.00580670964176312	0.0300283231673646
GO:0003887	DNA-directed DNA polymerase activity	11/4142	23/18639	0.478260869565217	2.15217391304348	0.00590248510877774	0.0301630931936752
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	11/4142	23/18639	0.478260869565217	2.15217391304348	0.00590248510877774	0.0301630931936752
GO:0008171	O-methyltransferase activity	11/4142	23/18639	0.478260869565217	2.15217391304348	0.00590248510877774	0.0301630931936752
GO:0004520	DNA endonuclease activity	17/4142	42/18639	0.404761904761905	1.82142857142857	0.00595278276692575	0.0301824688729282
GO:0035198	miRNA binding	17/4142	42/18639	0.404761904761905	1.82142857142857	0.00595278276692575	0.0301824688729282
GO:0031490	chromatin DNA binding	41/4142	128/18639	0.3203125	1.44140625	0.00652100559224002	0.0329348842752045
GO:0003924	GTPase activity	93/4142	331/18639	0.280966767371601	1.26435045317221	0.00674168803703624	0.0339174847754769
GO:0016278	lysine N-methyltransferase activity	25/4142	70/18639	0.357142857142857	1.60714285714286	0.00690655143286852	0.0346127558295882
GO:0004713	protein tyrosine kinase activity	44/4142	140/18639	0.314285714285714	1.41428571428571	0.00723749685663151	0.035601849232413
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	7/4142	12/18639	0.583333333333333	2.625	0.00724105408116875	0.035601849232413
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	7/4142	12/18639	0.583333333333333	2.625	0.00724105408116875	0.035601849232413
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	7/4142	12/18639	0.583333333333333	2.625	0.00724105408116875	0.035601849232413
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	7/4142	12/18639	0.583333333333333	2.625	0.00724105408116875	0.035601849232413
GO:0004712	protein serine/threonine/tyrosine kinase activity	17/4142	43/18639	0.395348837209302	1.77906976744186	0.00784123571330642	0.0382628720145554
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	17/4142	43/18639	0.395348837209302	1.77906976744186	0.00784123571330642	0.0382628720145554
GO:0035925	mRNA 3'-UTR AU-rich region binding	13/4142	30/18639	0.433333333333333	1.95	0.00797141458249356	0.0387524199553432
GO:0141050	histone H3K deacetylase activity	8/4142	15/18639	0.533333333333333	2.4	0.00831575293681043	0.0401258264385871
GO:0141051	histone H4K deacetylase activity	8/4142	15/18639	0.533333333333333	2.4	0.00831575293681043	0.0401258264385871
GO:0101005	deubiquitinase activity	37/4142	115/18639	0.321739130434783	1.44782608695652	0.00871096213552837	0.0417340036966005
GO:0001091	RNA polymerase II general transcription initiation factor binding	11/4142	24/18639	0.458333333333333	2.0625	0.00873752940586619	0.0417340036966005
GO:0045296	cadherin binding	93/4142	334/18639	0.278443113772455	1.25299401197605	0.00874549230005804	0.0417340036966005
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	9/4142	18/18639	0.5	2.25	0.00880894562758058	0.041882825731134
GO:0004843	cysteine-type deubiquitinase activity	35/4142	108/18639	0.324074074074074	1.45833333333333	0.00932812451970536	0.0441894365933488
GO:1990841	promoter-specific chromatin binding	24/4142	68/18639	0.352941176470588	1.58823529411765	0.0094424169418573	0.0445682079655664
GO:0042826	histone deacetylase binding	40/4142	127/18639	0.31496062992126	1.41732283464567	0.00970619032551332	0.0456472284149141
GO:0046332	SMAD binding	27/4142	79/18639	0.341772151898734	1.5379746835443	0.00989616910416308	0.0463726624447786
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	14/4142	34/18639	0.411764705882353	1.85294117647059	0.0101642954977186	0.0474577537987006
GO:0061980	regulatory RNA binding	21/4142	58/18639	0.362068965517241	1.62931034482759	0.0106744777319919	0.0490371350183584
GO:0001094	TFIID-class transcription factor complex binding	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0004445	inositol-polyphosphate 5-phosphatase activity	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0008641	ubiquitin-like modifier activating enzyme activity	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0030957	Tat protein binding	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0051880	G-quadruplex DNA binding	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	6/4142	10/18639	0.6	2.7	0.0109181294455359	0.0490371350183584
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	66/4142	229/18639	0.2882096069869	1.29694323144105	0.0112730956833284	0.0504568213688283
GO:0140693	molecular condensate scaffold activity	18/4142	48/18639	0.375	1.6875	0.0117522305550159	0.0520185630050389
GO:0019789	SUMO transferase activity	12/4142	28/18639	0.428571428571429	1.92857142857143	0.0117823247484449	0.0520185630050389
GO:0051019	mitogen-activated protein kinase binding	12/4142	28/18639	0.428571428571429	1.92857142857143	0.0117823247484449	0.0520185630050389
GO:0097718	disordered domain specific binding	12/4142	28/18639	0.428571428571429	1.92857142857143	0.0117823247484449	0.0520185630050389
GO:0019211	phosphatase activator activity	11/4142	25/18639	0.44	1.98	0.0125190679438221	0.0550838989528172
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	7/4142	13/18639	0.538461538461538	2.42307692307692	0.0127047049128091	0.0557118478946832
GO:0019001	guanyl nucleotide binding	108/4142	400/18639	0.27	1.215	0.013112516492661	0.0571142496895099
GO:0032561	guanyl ribonucleotide binding	108/4142	400/18639	0.27	1.215	0.013112516492661	0.0571142496895099
GO:0004708	MAP kinase kinase activity	8/4142	16/18639	0.5	2.25	0.0134291901734615	0.0577188372356058
GO:0017070	U6 snRNA binding	8/4142	16/18639	0.5	2.25	0.0134291901734615	0.0577188372356058
GO:0043023	ribosomal large subunit binding	8/4142	16/18639	0.5	2.25	0.0134291901734615	0.0577188372356058
GO:0140328	floppase activity	8/4142	16/18639	0.5	2.25	0.0134291901734615	0.0577188372356058
GO:0042800	histone H3K4 methyltransferase activity	9/4142	19/18639	0.473684210526316	2.13157894736842	0.0134815627786146	0.0577527012760456
GO:0034061	DNA polymerase activity	14/4142	35/18639	0.4	1.8	0.0135415023368576	0.0578186514251354
GO:0019888	protein phosphatase regulator activity	34/4142	107/18639	0.317757009345794	1.42990654205607	0.0140829069272112	0.0599331580049842
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/4142	23/18639	0.434782608695652	1.95652173913043	0.0186752790668122	0.0789867202724597
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	23/4142	68/18639	0.338235294117647	1.52205882352941	0.0186817589550425	0.0789867202724597
GO:0004143	ATP-dependent diacylglycerol kinase activity	6/4142	11/18639	0.545454545454545	2.45454545454545	0.0195441759429875	0.0811284047740176
GO:0019206	nucleoside kinase activity	6/4142	11/18639	0.545454545454545	2.45454545454545	0.0195441759429875	0.0811284047740176
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	6/4142	11/18639	0.545454545454545	2.45454545454545	0.0195441759429875	0.0811284047740176
GO:0070990	snRNP binding	6/4142	11/18639	0.545454545454545	2.45454545454545	0.0195441759429875	0.0811284047740176
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	6/4142	11/18639	0.545454545454545	2.45454545454545	0.0195441759429875	0.0811284047740176
GO:0140416	transcription regulator inhibitor activity	13/4142	33/18639	0.393939393939394	1.77272727272727	0.0195633210279411	0.0811284047740176
GO:0008170	N-methyltransferase activity	31/4142	98/18639	0.316326530612245	1.4234693877551	0.0196674105300017	0.0813003148660582
GO:0052745	inositol phosphate phosphatase activity	9/4142	20/18639	0.45	2.025	0.0197609880724022	0.0814278175173908
GO:0030331	nuclear estrogen receptor binding	15/4142	40/18639	0.375	1.6875	0.0204883891918884	0.0832939320787427
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	8/4142	17/18639	0.470588235294118	2.11764705882353	0.0205017914010318	0.0832939320787427
GO:0004549	tRNA-specific ribonuclease activity	8/4142	17/18639	0.470588235294118	2.11764705882353	0.0205017914010318	0.0832939320787427
GO:0008174	mRNA methyltransferase activity	7/4142	14/18639	0.5	2.25	0.0205988845895812	0.0832939320787427
GO:0034236	protein kinase A catalytic subunit binding	7/4142	14/18639	0.5	2.25	0.0205988845895812	0.0832939320787427
GO:0046030	inositol trisphosphate phosphatase activity	7/4142	14/18639	0.5	2.25	0.0205988845895812	0.0832939320787427
GO:0120013	lipid transfer activity	22/4142	65/18639	0.338461538461538	1.52307692307692	0.0209653055891769	0.0845123188035764
GO:0030544	Hsp70 protein binding	18/4142	51/18639	0.352941176470588	1.58823529411765	0.0227120933741208	0.0912702699678291
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	11/4142	27/18639	0.407407407407407	1.83333333333333	0.0236230477423703	0.0946380122518415
GO:0035035	histone acetyltransferase binding	10/4142	24/18639	0.416666666666667	1.875	0.0257736716817736	0.102547550946328
GO:0001727	lipid kinase activity	15/4142	41/18639	0.365853658536585	1.64634146341463	0.0258343984279271	0.102547550946328
GO:0042169	SH2 domain binding	15/4142	41/18639	0.365853658536585	1.64634146341463	0.0258343984279271	0.102547550946328
GO:0030295	protein kinase activator activity	41/4142	139/18639	0.294964028776978	1.3273381294964	0.0272680647362539	0.107580389141816
GO:0140767	enzyme-substrate adaptor activity	41/4142	139/18639	0.294964028776978	1.3273381294964	0.0272680647362539	0.107580389141816
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/4142	21/18639	0.428571428571429	1.92857142857143	0.0279035444937825	0.109092773352198
GO:0051010	microtubule plus-end binding	9/4142	21/18639	0.428571428571429	1.92857142857143	0.0279035444937825	0.109092773352198
GO:0072542	protein phosphatase activator activity	9/4142	21/18639	0.428571428571429	1.92857142857143	0.0279035444937825	0.109092773352198
GO:0008173	RNA methyltransferase activity	22/4142	67/18639	0.328358208955224	1.47761194029851	0.0296437818270254	0.115548434869306
GO:0000900	mRNA regulatory element binding translation repressor activity	8/4142	18/18639	0.444444444444444	2	0.0298560680197928	0.116027473921231
GO:0046966	nuclear thyroid hormone receptor binding	11/4142	28/18639	0.392857142857143	1.76785714285714	0.0312846920325573	0.120518345628684
GO:0042809	nuclear vitamin D receptor binding	7/4142	15/18639	0.466666666666667	2.1	0.0313466247857557	0.120518345628684
GO:0061578	K63-linked deubiquitinase activity	7/4142	15/18639	0.466666666666667	2.1	0.0313466247857557	0.120518345628684
GO:0004526	ribonuclease P activity	6/4142	12/18639	0.5	2.25	0.0318472978048063	0.120518345628684
GO:0005095	GTPase inhibitor activity	6/4142	12/18639	0.5	2.25	0.0318472978048063	0.120518345628684
GO:0035259	nuclear glucocorticoid receptor binding	6/4142	12/18639	0.5	2.25	0.0318472978048063	0.120518345628684
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	6/4142	12/18639	0.5	2.25	0.0318472978048063	0.120518345628684
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/4142	12/18639	0.5	2.25	0.0318472978048063	0.120518345628684
GO:1990817	poly(A) RNA polymerase activity	6/4142	12/18639	0.5	2.25	0.0318472978048063	0.120518345628684
GO:0019894	kinesin binding	15/4142	42/18639	0.357142857142857	1.60714285714286	0.0321509798322263	0.120612635324364
GO:0048487	beta-tubulin binding	15/4142	42/18639	0.357142857142857	1.60714285714286	0.0321509798322263	0.120612635324364
GO:0051879	Hsp90 protein binding	15/4142	42/18639	0.357142857142857	1.60714285714286	0.0321509798322263	0.120612635324364
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	10/4142	25/18639	0.4	1.8	0.0346100741737414	0.12909159849861
GO:0042974	nuclear retinoic acid receptor binding	10/4142	25/18639	0.4	1.8	0.0346100741737414	0.12909159849861
GO:0003777	microtubule motor activity	22/4142	68/18639	0.323529411764706	1.45588235294118	0.0348864884179737	0.129379034190085
GO:0005548	phospholipid transporter activity	22/4142	68/18639	0.323529411764706	1.45588235294118	0.0348864884179737	0.129379034190085
GO:0016504	peptidase activator activity	19/4142	57/18639	0.333333333333333	1.5	0.0355952112598306	0.13163129406057
GO:0022853	active monoatomic ion transmembrane transporter activity	35/4142	118/18639	0.296610169491525	1.33474576271186	0.0360946957203349	0.133099190468735
GO:0051287	NAD binding	18/4142	54/18639	0.333333333333333	1.5	0.0401039575213453	0.147464410375938
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	8/4142	19/18639	0.421052631578947	1.89473684210526	0.041764799104286	0.15270622320384
GO:0008301	DNA binding, bending	8/4142	19/18639	0.421052631578947	1.89473684210526	0.041764799104286	0.15270622320384
GO:0032451	demethylase activity	14/4142	40/18639	0.35	1.575	0.0445752171427319	0.16216795213673
GO:0016829	lyase activity	55/4142	200/18639	0.275	1.2375	0.0452437906201419	0.16216795213673
GO:0005521	lamin binding	7/4142	16/18639	0.4375	1.96875	0.0452824072619845	0.16216795213673
GO:0034450	ubiquitin-ubiquitin ligase activity	7/4142	16/18639	0.4375	1.96875	0.0452824072619845	0.16216795213673
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	7/4142	16/18639	0.4375	1.96875	0.0452824072619845	0.16216795213673
GO:0004529	DNA exonuclease activity	10/4142	26/18639	0.384615384615385	1.73076923076923	0.0453520544111194	0.16216795213673
GO:0070412	R-SMAD binding	10/4142	26/18639	0.384615384615385	1.73076923076923	0.0453520544111194	0.16216795213673
GO:0120014	phospholipid transfer activity	10/4142	26/18639	0.384615384615385	1.73076923076923	0.0453520544111194	0.16216795213673
GO:0019209	kinase activator activity	42/4142	148/18639	0.283783783783784	1.27702702702703	0.0465430331869144	0.165969387573118
GO:0019104	DNA N-glycosylase activity	6/4142	13/18639	0.461538461538462	2.07692307692308	0.0482552345693753	0.169528347274444
GO:0046974	histone H3K9 methyltransferase activity	6/4142	13/18639	0.461538461538462	2.07692307692308	0.0482552345693753	0.169528347274444
GO:0097157	pre-mRNA intronic binding	6/4142	13/18639	0.461538461538462	2.07692307692308	0.0482552345693753	0.169528347274444
GO:0140333	glycerophospholipid flippase activity	6/4142	13/18639	0.461538461538462	2.07692307692308	0.0482552345693753	0.169528347274444
GO:0140666	annealing activity	6/4142	13/18639	0.461538461538462	2.07692307692308	0.0482552345693753	0.169528347274444
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0032356	oxidized DNA binding	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0033204	ribonuclease P RNA binding	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0042975	peroxisome proliferator activated receptor binding	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0045322	unmethylated CpG binding	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0047429	nucleoside triphosphate diphosphatase activity	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0051864	histone H3K36 demethylase activity	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0070513	death domain binding	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0099122	RNA polymerase II C-terminal domain binding	5/4142	10/18639	0.5	2.25	0.049761402397198	0.169528347274444
GO:0051082	unfolded protein binding	35/4142	121/18639	0.289256198347107	1.30165289256198	0.050588767877313	0.171895865719247
GO:0035591	signaling adaptor activity	37/4142	129/18639	0.286821705426357	1.2906976744186	0.0509975446778659	0.172832409900444
GO:0032452	histone demethylase activity	11/4142	30/18639	0.366666666666667	1.65	0.051568805902609	0.173410129693229
GO:0051721	protein phosphatase 2A binding	11/4142	30/18639	0.366666666666667	1.65	0.051568805902609	0.173410129693229
GO:0070566	adenylyltransferase activity	11/4142	30/18639	0.366666666666667	1.65	0.051568805902609	0.173410129693229
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	14/4142	41/18639	0.341463414634146	1.53658536585366	0.0542926786985566	0.181161688819348
GO:0008137	NADH dehydrogenase (ubiquinone) activity	14/4142	41/18639	0.341463414634146	1.53658536585366	0.0542926786985566	0.181161688819348
GO:0016877	ligase activity, forming carbon-sulfur bonds	14/4142	41/18639	0.341463414634146	1.53658536585366	0.0542926786985566	0.181161688819348
GO:0015399	primary active transmembrane transporter activity	46/4142	166/18639	0.27710843373494	1.24698795180723	0.0558177489944414	0.185772918448166
GO:0042288	MHC class I protein binding	8/4142	20/18639	0.4	1.8	0.0564340064588751	0.186865664243928
GO:0043024	ribosomal small subunit binding	8/4142	20/18639	0.4	1.8	0.0564340064588751	0.186865664243928
GO:0030332	cyclin binding	12/4142	34/18639	0.352941176470588	1.58823529411765	0.0568999827346789	0.187929205062629
GO:0016835	carbon-oxygen lyase activity	24/4142	79/18639	0.30379746835443	1.36708860759494	0.0571333261251834	0.188220957640833
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	19/4142	60/18639	0.316666666666667	1.425	0.0581337234505137	0.190549753297107
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	10/4142	27/18639	0.37037037037037	1.66666666666667	0.0581338230397955	0.190549753297107
GO:0060590	ATPase regulator activity	16/4142	49/18639	0.326530612244898	1.46938775510204	0.0607191677707561	0.198522619059046
GO:0035401	histone H3Y41 kinase activity	33/4142	115/18639	0.28695652173913	1.29130434782609	0.0621213430638269	0.202088980693853
GO:0140801	histone H2AXY142 kinase activity	33/4142	115/18639	0.28695652173913	1.29130434782609	0.0621213430638269	0.202088980693853
GO:0140101	catalytic activity, acting on a tRNA	39/4142	139/18639	0.280575539568345	1.26258992805755	0.0623215938541599	0.202233572056749
GO:0005164	tumor necrosis factor receptor binding	11/4142	31/18639	0.354838709677419	1.59677419354839	0.0644192977769798	0.208000618195323
GO:0140457	protein demethylase activity	11/4142	31/18639	0.354838709677419	1.59677419354839	0.0644192977769798	0.208000618195323
GO:0031492	nucleosomal DNA binding	14/4142	42/18639	0.333333333333333	1.5	0.0653635281317217	0.210525705992493
GO:0051117	ATPase binding	25/4142	84/18639	0.297619047619048	1.33928571428571	0.0658733823305616	0.211642698675913
GO:0030276	clathrin binding	15/4142	46/18639	0.326086956521739	1.46739130434783	0.0686962779268598	0.220167330244603
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	6/4142	14/18639	0.428571428571429	1.92857142857143	0.0689974970542208	0.220588057084676
GO:0005154	epidermal growth factor receptor binding	12/4142	35/18639	0.342857142857143	1.54285714285714	0.0696939122542678	0.222267071513611
GO:0032813	tumor necrosis factor receptor superfamily binding	16/4142	50/18639	0.32	1.44	0.0715404723288899	0.227596894811027
GO:0004521	RNA endonuclease activity	22/4142	73/18639	0.301369863013699	1.35616438356164	0.0717472957061696	0.227696796642074
GO:0141052	histone H3 demethylase activity	10/4142	28/18639	0.357142857142857	1.60714285714286	0.0730500069327054	0.231265631704028
GO:0001618	virus receptor activity	24/4142	81/18639	0.296296296296296	1.33333333333333	0.0736229372759309	0.232512342053913
GO:0016776	phosphotransferase activity, phosphate group as acceptor	13/4142	39/18639	0.333333333333333	1.5	0.0741213955265607	0.233274021405757
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/4142	11/18639	0.454545454545455	2.04545454545454	0.0749424244423734	0.233274021405757
GO:0008526	phosphatidylinositol transfer activity	5/4142	11/18639	0.454545454545455	2.04545454545454	0.0749424244423734	0.233274021405757
GO:0042608	T cell receptor binding	5/4142	11/18639	0.454545454545455	2.04545454545454	0.0749424244423734	0.233274021405757
GO:0140031	phosphorylation-dependent protein binding	5/4142	11/18639	0.454545454545455	2.04545454545454	0.0749424244423734	0.233274021405757
GO:0180030	inositol phosphate kinase activity	5/4142	11/18639	0.454545454545455	2.04545454545454	0.0749424244423734	0.233274021405757
GO:0003779	actin binding	111/4142	443/18639	0.250564334085779	1.127539503386	0.0829453390854225	0.255572029486251
GO:0140272	exogenous protein binding	24/4142	82/18639	0.292682926829268	1.31707317073171	0.0829765899910523	0.255572029486251
GO:0019706	protein-cysteine S-palmitoyltransferase activity	9/4142	25/18639	0.36	1.62	0.0829892709166777	0.255572029486251
GO:0019707	protein-cysteine S-acyltransferase activity	9/4142	25/18639	0.36	1.62	0.0829892709166777	0.255572029486251
GO:0003746	translation elongation factor activity	7/4142	18/18639	0.388888888888889	1.75	0.0834842376750159	0.255572029486251
GO:0008409	5'-3' exonuclease activity	7/4142	18/18639	0.388888888888889	1.75	0.0834842376750159	0.255572029486251
GO:0050811	GABA receptor binding	7/4142	18/18639	0.388888888888889	1.75	0.0834842376750159	0.255572029486251
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	34/4142	122/18639	0.278688524590164	1.25409836065574	0.0838403009003181	0.256058142514383
GO:0016874	ligase activity	45/4142	167/18639	0.269461077844311	1.2125748502994	0.0856546010491508	0.260985145919713
GO:0036002	pre-mRNA binding	18/4142	59/18639	0.305084745762712	1.3728813559322	0.0875618894979641	0.266171739035966
GO:0016757	glycosyltransferase activity	69/4142	267/18639	0.258426966292135	1.16292134831461	0.0886682065819409	0.268904981643363
GO:0016417	S-acyltransferase activity	10/4142	29/18639	0.344827586206897	1.55172413793103	0.0901513814576538	0.272765718256491
GO:0001223	transcription coactivator binding	14/4142	44/18639	0.318181818181818	1.43181818181818	0.0917493453478163	0.275036143790914
GO:0003954	NADH dehydrogenase activity	14/4142	44/18639	0.318181818181818	1.43181818181818	0.0917493453478163	0.275036143790914
GO:0016790	thiolester hydrolase activity	14/4142	44/18639	0.318181818181818	1.43181818181818	0.0917493453478163	0.275036143790914
GO:0043014	alpha-tubulin binding	14/4142	44/18639	0.318181818181818	1.43181818181818	0.0917493453478163	0.275036143790914
GO:0008135	translation factor activity, RNA binding	24/4142	83/18639	0.289156626506024	1.30120481927711	0.0930917423958719	0.278417238778437
GO:0050700	CARD domain binding	6/4142	15/18639	0.4	1.8	0.0940980785665307	0.279986712585095
GO:0120283	protein serine/threonine kinase binding	6/4142	15/18639	0.4	1.8	0.0940980785665307	0.279986712585095
GO:0008649	rRNA methyltransferase activity	8/4142	22/18639	0.363636363636364	1.63636363636364	0.0944793375287147	0.279986712585095
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	8/4142	22/18639	0.363636363636364	1.63636363636364	0.0944793375287147	0.279986712585095
GO:0030159	signaling receptor complex adaptor activity	16/4142	52/18639	0.307692307692308	1.38461538461538	0.0968252723818088	0.286285201712045
GO:0019213	deacetylase activity	12/4142	37/18639	0.324324324324324	1.45945945945946	0.100472045770989	0.296392535024417
GO:0009055	electron transfer activity	32/4142	116/18639	0.275862068965517	1.24137931034483	0.101894474735141	0.299907093438124
GO:0052742	phosphatidylinositol kinase activity	9/4142	26/18639	0.346153846153846	1.55769230769231	0.102914856125503	0.301605726957995
GO:0000049	tRNA binding	23/4142	80/18639	0.2875	1.29375	0.103799070914561	0.301605726957995
GO:0003774	cytoskeletal motor activity	41/4142	153/18639	0.26797385620915	1.20588235294118	0.103858685753416	0.301605726957995
GO:0180051	translation factor activity	24/4142	84/18639	0.285714285714286	1.28571428571429	0.103979086421997	0.301605726957995
GO:0000995	RNA polymerase III general transcription initiation factor activity	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0004126	cytidine deaminase activity	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0016273	arginine N-methyltransferase activity	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0016274	protein-arginine N-methyltransferase activity	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0017166	vinculin binding	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0034452	dynactin binding	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0070008	serine-type exopeptidase activity	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0097677	STAT family protein binding	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/4142	12/18639	0.416666666666667	1.875	0.105724657754921	0.301605726957995
GO:0140303	intramembrane lipid transporter activity	14/4142	45/18639	0.311111111111111	1.4	0.107110975585197	0.304241540739076
GO:0008574	plus-end-directed microtubule motor activity	7/4142	19/18639	0.368421052631579	1.65789473684211	0.107820576841275	0.304241540739076
GO:0050145	nucleoside monophosphate kinase activity	7/4142	19/18639	0.368421052631579	1.65789473684211	0.107820576841275	0.304241540739076
GO:0120227	acyl-CoA binding	7/4142	19/18639	0.368421052631579	1.65789473684211	0.107820576841275	0.304241540739076
GO:1990380	K48-linked deubiquitinase activity	7/4142	19/18639	0.368421052631579	1.65789473684211	0.107820576841275	0.304241540739076
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	18/4142	61/18639	0.295081967213115	1.32786885245902	0.113865900072417	0.320602903023857
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	11/4142	34/18639	0.323529411764706	1.45588235294118	0.114520669907749	0.321748548788438
GO:0035091	phosphatidylinositol binding	72/4142	284/18639	0.253521126760563	1.14084507042254	0.114806033126874	0.321853630666701
GO:0043274	phospholipase binding	8/4142	23/18639	0.347826086956522	1.56521739130435	0.117855996511268	0.328982975207797
GO:0140102	catalytic activity, acting on a rRNA	8/4142	23/18639	0.347826086956522	1.56521739130435	0.117855996511268	0.328982975207797
GO:0000062	fatty-acyl-CoA binding	6/4142	16/18639	0.375	1.6875	0.123387481349259	0.340035988941269
GO:0004707	MAP kinase activity	6/4142	16/18639	0.375	1.6875	0.123387481349259	0.340035988941269
GO:0015562	efflux transmembrane transporter activity	6/4142	16/18639	0.375	1.6875	0.123387481349259	0.340035988941269
GO:0030275	LRR domain binding	6/4142	16/18639	0.375	1.6875	0.123387481349259	0.340035988941269
GO:0070411	I-SMAD binding	6/4142	16/18639	0.375	1.6875	0.123387481349259	0.340035988941269
GO:0140327	flippase activity	6/4142	16/18639	0.375	1.6875	0.123387481349259	0.340035988941269
GO:0001671	ATPase activator activity	9/4142	27/18639	0.333333333333333	1.5	0.125305372668356	0.34458977483798
GO:0016004	phospholipase activator activity	7/4142	20/18639	0.35	1.575	0.135490268585644	0.371810504490837
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/4142	13/18639	0.384615384615385	1.73076923076923	0.141643047245888	0.386245116229332
GO:0005035	death receptor activity	5/4142	13/18639	0.384615384615385	1.73076923076923	0.141643047245888	0.386245116229332
GO:0035673	oligopeptide transmembrane transporter activity	5/4142	13/18639	0.384615384615385	1.73076923076923	0.141643047245888	0.386245116229332
GO:0043495	protein-membrane adaptor activity	14/4142	47/18639	0.297872340425532	1.34042553191489	0.142143278708079	0.386796594891167
GO:0005048	signal sequence binding	15/4142	51/18639	0.294117647058824	1.32352941176471	0.143277994097103	0.388583999811922
GO:0019003	GDP binding	21/4142	75/18639	0.28	1.26	0.143506148833478	0.388583999811922
GO:0050699	WW domain binding	8/4142	24/18639	0.333333333333333	1.5	0.143997614722291	0.388583999811922
GO:0070300	phosphatidic acid binding	8/4142	24/18639	0.333333333333333	1.5	0.143997614722291	0.388583999811922
GO:0051537	2 iron, 2 sulfur cluster binding	9/4142	28/18639	0.321428571428571	1.44642857142857	0.150057914332612	0.404097868887407
GO:0038191	neuropilin binding	6/4142	17/18639	0.352941176470588	1.58823529411765	0.156528559340862	0.417195215655933
GO:0046965	nuclear retinoid X receptor binding	6/4142	17/18639	0.352941176470588	1.58823529411765	0.156528559340862	0.417195215655933
GO:0051787	misfolded protein binding	6/4142	17/18639	0.352941176470588	1.58823529411765	0.156528559340862	0.417195215655933
GO:0070403	NAD+ binding	6/4142	17/18639	0.352941176470588	1.58823529411765	0.156528559340862	0.417195215655933
GO:1901567	fatty acid derivative binding	6/4142	17/18639	0.352941176470588	1.58823529411765	0.156528559340862	0.417195215655933
GO:0044390	ubiquitin-like protein conjugating enzyme binding	11/4142	36/18639	0.305555555555556	1.375	0.157443121646239	0.418772893231186
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	12/4142	40/18639	0.3	1.35	0.159550833475514	0.423471679919446
GO:0016853	isomerase activity	46/4142	180/18639	0.255555555555556	1.15	0.160710413297603	0.423471679919446
GO:0003680	minor groove of adenine-thymine-rich DNA binding	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0005031	tumor necrosis factor receptor activity	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0005131	growth hormone receptor binding	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0005522	profilin binding	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0016783	sulfurtransferase activity	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0031434	mitogen-activated protein kinase kinase binding	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0140999	histone H3K4 trimethyltransferase activity	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:1905394	retromer complex binding	4/4142	10/18639	0.4	1.8	0.1631246840984	0.423471679919446
GO:0005123	death receptor binding	7/4142	21/18639	0.333333333333333	1.5	0.166239795967462	0.428984602715239
GO:0035613	RNA stem-loop binding	7/4142	21/18639	0.333333333333333	1.5	0.166239795967462	0.428984602715239
GO:0140312	cargo adaptor activity	7/4142	21/18639	0.333333333333333	1.5	0.166239795967462	0.428984602715239
GO:0035250	UDP-galactosyltransferase activity	9/4142	29/18639	0.310344827586207	1.39655172413793	0.177015854126343	0.454983324071274
GO:0106222	lncRNA binding	9/4142	29/18639	0.310344827586207	1.39655172413793	0.177015854126343	0.454983324071274
GO:0160215	deacylase activity	18/4142	65/18639	0.276923076923077	1.24615384615385	0.179201271878695	0.459690219167086
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	10/4142	33/18639	0.303030303030303	1.36363636363636	0.179821763862914	0.460372089731878
GO:0044548	S100 protein binding	5/4142	14/18639	0.357142857142857	1.60714285714286	0.182001686241258	0.461800426460966
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/4142	14/18639	0.357142857142857	1.60714285714286	0.182001686241258	0.461800426460966
GO:0061665	SUMO ligase activity	5/4142	14/18639	0.357142857142857	1.60714285714286	0.182001686241258	0.461800426460966
GO:0016860	intramolecular oxidoreductase activity	15/4142	53/18639	0.283018867924528	1.27358490566038	0.182158565753478	0.461800426460966
GO:0051018	protein kinase A binding	15/4142	53/18639	0.283018867924528	1.27358490566038	0.182158565753478	0.461800426460966
GO:0019210	kinase inhibitor activity	24/4142	90/18639	0.266666666666667	1.2	0.185447908444021	0.469222973022105
GO:0008308	voltage-gated monoatomic anion channel activity	6/4142	18/18639	0.333333333333333	1.5	0.193050720173786	0.484680531500143
GO:0008525	phosphatidylcholine transporter activity	6/4142	18/18639	0.333333333333333	1.5	0.193050720173786	0.484680531500143
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	6/4142	18/18639	0.333333333333333	1.5	0.193050720173786	0.484680531500143
GO:0035615	clathrin adaptor activity	6/4142	18/18639	0.333333333333333	1.5	0.193050720173786	0.484680531500143
GO:0140517	protein-RNA adaptor activity	7/4142	22/18639	0.318181818181818	1.43181818181818	0.199728009905544	0.500476750689954
GO:0015485	cholesterol binding	15/4142	54/18639	0.277777777777778	1.25	0.203354034634581	0.508580996061052
GO:0031624	ubiquitin conjugating enzyme binding	9/4142	30/18639	0.3	1.35	0.205975790508272	0.513193349943334
GO:0030291	protein serine/threonine kinase inhibitor activity	13/4142	46/18639	0.282608695652174	1.27173913043478	0.205989010262309	0.513193349943334
GO:0008376	acetylgalactosaminyltransferase activity	10/4142	34/18639	0.294117647058824	1.32352941176471	0.207030553010899	0.514339045683058
GO:0043531	ADP binding	11/4142	38/18639	0.289473684210526	1.30263157894737	0.20724138743624	0.514339045683058
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/4142	11/18639	0.363636363636364	1.63636363636364	0.213514546758986	0.523897696962503
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	4/4142	11/18639	0.363636363636364	1.63636363636364	0.213514546758986	0.523897696962503
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/4142	11/18639	0.363636363636364	1.63636363636364	0.213514546758986	0.523897696962503
GO:0015173	aromatic amino acid transmembrane transporter activity	4/4142	11/18639	0.363636363636364	1.63636363636364	0.213514546758986	0.523897696962503
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/4142	11/18639	0.363636363636364	1.63636363636364	0.213514546758986	0.523897696962503
GO:0140537	transcription regulator activator activity	4/4142	11/18639	0.363636363636364	1.63636363636364	0.213514546758986	0.523897696962503
GO:0004860	protein kinase inhibitor activity	22/4142	84/18639	0.261904761904762	1.17857142857143	0.224830538065778	0.547178414406812
GO:0000774	adenyl-nucleotide exchange factor activity	5/4142	15/18639	0.333333333333333	1.5	0.225953490078622	0.547178414406812
GO:0004129	cytochrome-c oxidase activity	5/4142	15/18639	0.333333333333333	1.5	0.225953490078622	0.547178414406812
GO:0004953	icosanoid receptor activity	5/4142	15/18639	0.333333333333333	1.5	0.225953490078622	0.547178414406812
GO:0016846	carbon-sulfur lyase activity	5/4142	15/18639	0.333333333333333	1.5	0.225953490078622	0.547178414406812
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/4142	15/18639	0.333333333333333	1.5	0.225953490078622	0.547178414406812
GO:0047372	monoacylglycerol lipase activity	5/4142	15/18639	0.333333333333333	1.5	0.225953490078622	0.547178414406812
GO:0008375	acetylglucosaminyltransferase activity	12/4142	43/18639	0.27906976744186	1.25581395348837	0.232524803056109	0.56204319248944
GO:0005319	lipid transporter activity	44/4142	178/18639	0.247191011235955	1.1123595505618	0.234977949616437	0.565922497553778
GO:0042171	lysophosphatidic acid acyltransferase activity	7/4142	23/18639	0.304347826086957	1.3695652173913	0.23554701576554	0.565922497553778
GO:0071617	lysophospholipid acyltransferase activity	7/4142	23/18639	0.304347826086957	1.3695652173913	0.23554701576554	0.565922497553778
GO:0072349	modified amino acid transmembrane transporter activity	9/4142	31/18639	0.290322580645161	1.30645161290323	0.236695826199565	0.565922497553778
GO:0004683	calcium/calmodulin-dependent protein kinase activity	8/4142	27/18639	0.296296296296296	1.33333333333333	0.2367456981292	0.565922497553778
GO:0005385	zinc ion transmembrane transporter activity	8/4142	27/18639	0.296296296296296	1.33333333333333	0.2367456981292	0.565922497553778
GO:0051015	actin filament binding	51/4142	209/18639	0.244019138755981	1.09808612440191	0.246143576427856	0.587305812873818
GO:0019212	phosphatase inhibitor activity	15/4142	56/18639	0.267857142857143	1.20535714285714	0.24884341758885	0.592658267945555
GO:0005484	SNAP receptor activity	10/4142	36/18639	0.277777777777778	1.25	0.265959784927014	0.620925795450451
GO:0016409	palmitoyltransferase activity	10/4142	36/18639	0.277777777777778	1.25	0.265959784927014	0.620925795450451
GO:0000340	RNA 7-methylguanosine cap binding	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0003995	acyl-CoA dehydrogenase activity	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0004300	enoyl-CoA hydratase activity	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0008179	adenylate cyclase binding	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0016840	carbon-nitrogen lyase activity	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0035197	siRNA binding	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0035497	cAMP response element binding	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0042301	phosphate ion binding	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0070679	inositol 1,4,5 trisphosphate binding	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0097371	MDM2/MDM4 family protein binding	4/4142	12/18639	0.333333333333333	1.5	0.267409491261019	0.620925795450451
GO:0008378	galactosyltransferase activity	9/4142	32/18639	0.28125	1.265625	0.268904619088027	0.622171471615435
GO:0031369	translation initiation factor binding	9/4142	32/18639	0.28125	1.265625	0.268904619088027	0.622171471615435
GO:0046875	ephrin receptor binding	8/4142	28/18639	0.285714285714286	1.28571428571429	0.271420811647835	0.623757734885637
GO:0008296	3'-5'-DNA exonuclease activity	5/4142	16/18639	0.3125	1.40625	0.272574403137424	0.623757734885637
GO:0016675	oxidoreductase activity, acting on a heme group of donors	5/4142	16/18639	0.3125	1.40625	0.272574403137424	0.623757734885637
GO:0022858	alanine transmembrane transporter activity	5/4142	16/18639	0.3125	1.40625	0.272574403137424	0.623757734885637
GO:0097027	ubiquitin-protein transferase activator activity	5/4142	16/18639	0.3125	1.40625	0.272574403137424	0.623757734885637
GO:0004622	lysophospholipase activity	7/4142	24/18639	0.291666666666667	1.3125	0.273243827959819	0.623757734885637
GO:0060229	lipase activator activity	7/4142	24/18639	0.291666666666667	1.3125	0.273243827959819	0.623757734885637
GO:0015095	magnesium ion transmembrane transporter activity	6/4142	20/18639	0.3	1.35	0.273915184040688	0.623757734885637
GO:0140939	histone H4 methyltransferase activity	6/4142	20/18639	0.3	1.35	0.273915184040688	0.623757734885637
GO:0097110	scaffold protein binding	18/4142	70/18639	0.257142857142857	1.15714285714286	0.281662000319356	0.640275440305647
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	32/4142	130/18639	0.246153846153846	1.10769230769231	0.285697514315751	0.648313590178051
GO:0046915	transition metal ion transmembrane transporter activity	12/4142	45/18639	0.266666666666667	1.2	0.287219076207363	0.650628902124184
GO:0042287	MHC protein binding	11/4142	41/18639	0.268292682926829	1.20731707317073	0.292182640738457	0.660719630101946
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	15/4142	58/18639	0.258620689655172	1.16379310344828	0.297782800686917	0.672212304854988
GO:0044183	protein folding chaperone	19/4142	75/18639	0.253333333333333	1.14	0.298471223710633	0.672596611764587
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	14/4142	54/18639	0.259259259259259	1.16666666666667	0.303571941674801	0.681723841338913
GO:0050661	NADP binding	14/4142	54/18639	0.259259259259259	1.16666666666667	0.303571941674801	0.681723841338913
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	8/4142	29/18639	0.275862068965517	1.24137931034483	0.307384604989356	0.689093639509817
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	17/4142	67/18639	0.253731343283582	1.14179104477612	0.310334987320277	0.694508299209861
GO:0015662	P-type ion transporter activity	7/4142	25/18639	0.28	1.26	0.312341318555085	0.69659627402835
GO:0140358	P-type transmembrane transporter activity	7/4142	25/18639	0.28	1.26	0.312341318555085	0.69659627402835
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/4142	21/18639	0.285714285714286	1.28571428571429	0.316985339269979	0.703328154482792
GO:0008373	sialyltransferase activity	6/4142	21/18639	0.285714285714286	1.28571428571429	0.316985339269979	0.703328154482792
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/4142	21/18639	0.285714285714286	1.28571428571429	0.316985339269979	0.703328154482792
GO:0004550	nucleoside diphosphate kinase activity	5/4142	17/18639	0.294117647058824	1.32352941176471	0.320926838052658	0.704844392203637
GO:0005092	GDP-dissociation inhibitor activity	5/4142	17/18639	0.294117647058824	1.32352941176471	0.320926838052658	0.704844392203637
GO:0008429	phosphatidylethanolamine binding	5/4142	17/18639	0.294117647058824	1.32352941176471	0.320926838052658	0.704844392203637
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/4142	17/18639	0.294117647058824	1.32352941176471	0.320926838052658	0.704844392203637
GO:0017110	nucleoside diphosphate phosphatase activity	5/4142	17/18639	0.294117647058824	1.32352941176471	0.320926838052658	0.704844392203637
GO:0032977	membrane insertase activity	5/4142	17/18639	0.294117647058824	1.32352941176471	0.320926838052658	0.704844392203637
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/4142	13/18639	0.307692307692308	1.38461538461538	0.323305688601077	0.705295434965038
GO:0003964	RNA-directed DNA polymerase activity	4/4142	13/18639	0.307692307692308	1.38461538461538	0.323305688601077	0.705295434965038
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/4142	13/18639	0.307692307692308	1.38461538461538	0.323305688601077	0.705295434965038
GO:0009982	pseudouridine synthase activity	4/4142	13/18639	0.307692307692308	1.38461538461538	0.323305688601077	0.705295434965038
GO:0042887	amide transmembrane transporter activity	10/4142	38/18639	0.263157894736842	1.18421052631579	0.329360715250616	0.717299007374665
GO:1901981	phosphatidylinositol phosphate binding	44/4142	185/18639	0.237837837837838	1.07027027027027	0.330824877846627	0.7192808901925
GO:0032934	sterol binding	17/4142	68/18639	0.25	1.125	0.334341380445726	0.725710889328682
GO:0015101	organic cation transmembrane transporter activity	20/4142	81/18639	0.246913580246914	1.11111111111111	0.336484040047103	0.727927139968566
GO:0030971	receptor tyrosine kinase binding	20/4142	81/18639	0.246913580246914	1.11111111111111	0.336484040047103	0.727927139968566
GO:0003743	translation initiation factor activity	13/4142	51/18639	0.254901960784314	1.14705882352941	0.337488704196575	0.728885753822219
GO:0031210	phosphatidylcholine binding	8/4142	30/18639	0.266666666666667	1.2	0.344260537527931	0.742276042709726
GO:0140359	ABC-type transporter activity	12/4142	47/18639	0.25531914893617	1.14893617021277	0.345198647615878	0.743064418914443
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	15/4142	60/18639	0.25	1.125	0.349242184644168	0.749770256360095
GO:0005160	transforming growth factor beta receptor binding	7/4142	26/18639	0.269230769230769	1.21153846153846	0.352357362388026	0.749770256360095
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	7/4142	26/18639	0.269230769230769	1.21153846153846	0.352357362388026	0.749770256360095
GO:0034237	protein kinase A regulatory subunit binding	7/4142	26/18639	0.269230769230769	1.21153846153846	0.352357362388026	0.749770256360095
GO:0043548	phosphatidylinositol 3-kinase binding	7/4142	26/18639	0.269230769230769	1.21153846153846	0.352357362388026	0.749770256360095
GO:0050681	nuclear androgen receptor binding	7/4142	26/18639	0.269230769230769	1.21153846153846	0.352357362388026	0.749770256360095
GO:0097602	cullin family protein binding	7/4142	26/18639	0.269230769230769	1.21153846153846	0.352357362388026	0.749770256360095
GO:1990782	protein tyrosine kinase binding	28/4142	117/18639	0.239316239316239	1.07692307692308	0.362222132596718	0.769499718675189
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/4142	18/18639	0.277777777777778	1.25	0.370109960313762	0.783691237336482
GO:1901611	phosphatidylglycerol binding	5/4142	18/18639	0.277777777777778	1.25	0.370109960313762	0.783691237336482
GO:0016836	hydro-lyase activity	15/4142	61/18639	0.245901639344262	1.10655737704918	0.375604798619012	0.789576187336232
GO:0004705	JUN kinase activity	4/4142	14/18639	0.285714285714286	1.28571428571429	0.379827289545004	0.789576187336232
GO:0005545	1-phosphatidylinositol binding	4/4142	14/18639	0.285714285714286	1.28571428571429	0.379827289545004	0.789576187336232
GO:0008559	ABC-type xenobiotic transporter activity	4/4142	14/18639	0.285714285714286	1.28571428571429	0.379827289545004	0.789576187336232
GO:0042043	neurexin family protein binding	4/4142	14/18639	0.285714285714286	1.28571428571429	0.379827289545004	0.789576187336232
GO:0070742	C2H2 zinc finger domain binding	4/4142	14/18639	0.285714285714286	1.28571428571429	0.379827289545004	0.789576187336232
GO:1990825	sequence-specific mRNA binding	4/4142	14/18639	0.285714285714286	1.28571428571429	0.379827289545004	0.789576187336232
GO:0016411	acylglycerol O-acyltransferase activity	8/4142	31/18639	0.258064516129032	1.16129032258065	0.381674350163885	0.789576187336232
GO:0016878	acid-thiol ligase activity	8/4142	31/18639	0.258064516129032	1.16129032258065	0.381674350163885	0.789576187336232
GO:0015932	nucleobase-containing compound transmembrane transporter activity	14/4142	57/18639	0.245614035087719	1.10526315789474	0.384777285439623	0.789576187336232
GO:0004090	carbonyl reductase (NADPH) activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0004955	prostaglandin receptor activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0008140	cAMP response element binding protein binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0008190	eukaryotic initiation factor 4E binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0008239	dipeptidyl-peptidase activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0016427	tRNA (cytidine) methyltransferase activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0031419	cobalamin binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0031996	thioesterase binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0043422	protein kinase B binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0050815	phosphoserine residue binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0097177	mitochondrial ribosome binding	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0140940	histone H2A methyltransferase activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:1990259	histone H2AQ104 methyltransferase activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:1990757	ubiquitin ligase activator activity	3/4142	10/18639	0.3	1.35	0.389921676488848	0.789576187336232
GO:0008194	UDP-glycosyltransferase activity	34/4142	145/18639	0.23448275862069	1.0551724137931	0.392353418311069	0.790478769726984
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	7/4142	27/18639	0.259259259259259	1.16666666666667	0.392821444878616	0.790478769726984
GO:0004177	aminopeptidase activity	10/4142	40/18639	0.25	1.125	0.395239384863492	0.790478769726984
GO:0015036	disulfide oxidoreductase activity	10/4142	40/18639	0.25	1.125	0.395239384863492	0.790478769726984
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	10/4142	40/18639	0.25	1.125	0.395239384863492	0.790478769726984
GO:0050997	quaternary ammonium group binding	10/4142	40/18639	0.25	1.125	0.395239384863492	0.790478769726984
GO:0061791	GTPase motor activity	10/4142	40/18639	0.25	1.125	0.395239384863492	0.790478769726984
GO:1990606	membrane scission GTPase motor activity	10/4142	40/18639	0.25	1.125	0.395239384863492	0.790478769726984
GO:0005158	insulin receptor binding	6/4142	23/18639	0.260869565217391	1.17391304347826	0.405219127904972	0.805915355491408
GO:0016849	phosphorus-oxygen lyase activity	6/4142	23/18639	0.260869565217391	1.17391304347826	0.405219127904972	0.805915355491408
GO:0055106	ubiquitin-protein transferase regulator activity	9/4142	36/18639	0.25	1.125	0.406683018372012	0.805915355491408
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	9/4142	36/18639	0.25	1.125	0.406683018372012	0.805915355491408
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	9/4142	36/18639	0.25	1.125	0.406683018372012	0.805915355491408
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	9/4142	36/18639	0.25	1.125	0.406683018372012	0.805915355491408
GO:0051213	dioxygenase activity	22/4142	93/18639	0.236559139784946	1.06451612903226	0.408976147564823	0.809224145638934
GO:0008238	exopeptidase activity	24/4142	102/18639	0.235294117647059	1.05882352941176	0.412968453583719	0.815879836760529
GO:0070717	poly-purine tract binding	8/4142	32/18639	0.25	1.125	0.419264260522504	0.823368879103621
GO:0120015	sterol transfer activity	8/4142	32/18639	0.25	1.125	0.419264260522504	0.823368879103621
GO:0031420	alkali metal ion binding	5/4142	19/18639	0.263157894736842	1.18421052631579	0.419296478495758	0.823368879103621
GO:0046624	sphingolipid transporter activity	5/4142	19/18639	0.263157894736842	1.18421052631579	0.419296478495758	0.823368879103621
GO:0042626	ATPase-coupled transmembrane transporter activity	23/4142	98/18639	0.23469387755102	1.05612244897959	0.421720121403705	0.826877216891252
GO:0003925	G protein activity	13/4142	54/18639	0.240740740740741	1.08333333333333	0.423390145746693	0.828899561356271
GO:0140318	protein transporter activity	10/4142	41/18639	0.24390243902439	1.09756097560976	0.428483495871568	0.837607797652554
GO:0016866	intramolecular transferase activity	7/4142	28/18639	0.25	1.125	0.43328832262221	0.840481805612999
GO:0015605	organophosphate ester transmembrane transporter activity	12/4142	50/18639	0.24	1.08	0.435127610591964	0.840481805612999
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/4142	15/18639	0.266666666666667	1.2	0.435781398441871	0.840481805612999
GO:0015929	hexosaminidase activity	4/4142	15/18639	0.266666666666667	1.2	0.435781398441871	0.840481805612999
GO:0031386	protein tag activity	4/4142	15/18639	0.266666666666667	1.2	0.435781398441871	0.840481805612999
GO:0050780	dopamine receptor binding	4/4142	15/18639	0.266666666666667	1.2	0.435781398441871	0.840481805612999
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/4142	15/18639	0.266666666666667	1.2	0.435781398441871	0.840481805612999
GO:0140776	protein-containing complex destabilizing activity	4/4142	15/18639	0.266666666666667	1.2	0.435781398441871	0.840481805612999
GO:0141047	molecular tag activity	4/4142	15/18639	0.266666666666667	1.2	0.435781398441871	0.840481805612999
GO:0140223	general transcription initiation factor activity	16/4142	68/18639	0.235294117647059	1.05882352941176	0.444254838004435	0.850477539877435
GO:0030552	cAMP binding	6/4142	24/18639	0.25	1.125	0.449210894553357	0.850477539877435
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/4142	24/18639	0.25	1.125	0.449210894553357	0.850477539877435
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/4142	24/18639	0.25	1.125	0.449210894553357	0.850477539877435
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/4142	24/18639	0.25	1.125	0.449210894553357	0.850477539877435
GO:0070840	dynein complex binding	6/4142	24/18639	0.25	1.125	0.449210894553357	0.850477539877435
GO:0002162	dystroglycan binding	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0003953	NAD+ nucleosidase activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0004954	prostanoid receptor activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0005114	type II transforming growth factor beta receptor binding	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0005225	volume-sensitive anion channel activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0005536	D-glucose binding	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0008172	S-methyltransferase activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0008432	JUN kinase binding	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0019107	myristoyltransferase activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0032050	clathrin heavy chain binding	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0035252	UDP-xylosyltransferase activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0042285	xylosyltransferase activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0043522	leucine zipper domain binding	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0047676	arachidonate-CoA ligase activity	3/4142	11/18639	0.272727272727273	1.22727272727273	0.456074350137546	0.850477539877435
GO:0019239	deaminase activity	8/4142	33/18639	0.242424242424242	1.09090909090909	0.456689403154524	0.850477539877435
GO:0016830	carbon-carbon lyase activity	12/4142	51/18639	0.235294117647059	1.05882352941176	0.465170351021315	0.865030251612703
GO:0000339	RNA cap binding	5/4142	20/18639	0.25	1.125	0.467756909980781	0.866117645014342
GO:0016505	peptidase activator activity involved in apoptotic process	5/4142	20/18639	0.25	1.125	0.467756909980781	0.866117645014342
GO:0030742	GTP-dependent protein binding	5/4142	20/18639	0.25	1.125	0.467756909980781	0.866117645014342
GO:0044325	transmembrane transporter binding	31/4142	136/18639	0.227941176470588	1.02573529411765	0.469564436619237	0.868225981099387
GO:0051861	glycolipid binding	7/4142	29/18639	0.241379310344828	1.08620689655172	0.473348596414481	0.873977920549071
GO:0043178	alcohol binding	21/4142	92/18639	0.228260869565217	1.02717391304348	0.485181289017007	0.894553001625107
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/4142	16/18639	0.25	1.125	0.490183730210019	0.898670172051702
GO:0005159	insulin-like growth factor receptor binding	4/4142	16/18639	0.25	1.125	0.490183730210019	0.898670172051702
GO:0015923	mannosidase activity	4/4142	16/18639	0.25	1.125	0.490183730210019	0.898670172051702
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/4142	16/18639	0.25	1.125	0.490183730210019	0.898670172051702
GO:0003707	nuclear steroid receptor activity	6/4142	25/18639	0.24	1.08	0.492432865921233	0.898984331878707
GO:0047617	fatty acyl-CoA hydrolase activity	6/4142	25/18639	0.24	1.08	0.492432865921233	0.898984331878707
GO:0120020	cholesterol transfer activity	6/4142	25/18639	0.24	1.08	0.492432865921233	0.898984331878707
GO:0008175	tRNA methyltransferase activity	8/4142	34/18639	0.235294117647059	1.05882352941176	0.4936364382665	0.899915866390334
GO:0016879	ligase activity, forming carbon-nitrogen bonds	11/4142	48/18639	0.229166666666667	1.03125	0.510139834447564	0.922758222035314
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	9/4142	39/18639	0.230769230769231	1.03846153846154	0.511181338890926	0.922758222035314
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	9/4142	39/18639	0.230769230769231	1.03846153846154	0.511181338890926	0.922758222035314
GO:0008187	poly-pyrimidine tract binding	7/4142	30/18639	0.233333333333333	1.05	0.512636266510388	0.922758222035314
GO:0016769	transferase activity, transferring nitrogenous groups	7/4142	30/18639	0.233333333333333	1.05	0.512636266510388	0.922758222035314
GO:0003720	telomerase activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0005078	MAP-kinase scaffold activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0008603	cAMP-dependent protein kinase regulator activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0010853	cyclase activator activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0015132	prostaglandin transmembrane transporter activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0016423	tRNA (guanine) methyltransferase activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0016801	hydrolase activity, acting on ether bonds	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0016803	ether hydrolase activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0035251	UDP-glucosyltransferase activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0036009	protein-glutamine N-methyltransferase activity	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0045295	gamma-catenin binding	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:1990459	transferrin receptor binding	3/4142	12/18639	0.25	1.125	0.518962636429722	0.922758222035314
GO:0140299	molecular sensor activity	16/4142	71/18639	0.225352112676056	1.01408450704225	0.521108330538201	0.925305900189583
GO:0004864	protein phosphatase inhibitor activity	12/4142	53/18639	0.226415094339623	1.0188679245283	0.524355061246749	0.928530517732987
GO:0016251	RNA polymerase II general transcription initiation factor activity	12/4142	53/18639	0.226415094339623	1.0188679245283	0.524355061246749	0.928530517732987
GO:0004435	phosphatidylinositol phospholipase C activity	6/4142	26/18639	0.230769230769231	1.03846153846154	0.534455516981195	0.941279865728074
GO:0008157	protein phosphatase 1 binding	6/4142	26/18639	0.230769230769231	1.03846153846154	0.534455516981195	0.941279865728074
GO:0016289	acyl-CoA hydrolase activity	6/4142	26/18639	0.230769230769231	1.03846153846154	0.534455516981195	0.941279865728074
GO:0070006	metalloaminopeptidase activity	6/4142	26/18639	0.230769230769231	1.03846153846154	0.534455516981195	0.941279865728074
GO:0016018	cyclosporin A binding	4/4142	17/18639	0.235294117647059	1.05882352941176	0.542262773950746	0.952445305261256
GO:0048038	quinone binding	4/4142	17/18639	0.235294117647059	1.05882352941176	0.542262773950746	0.952445305261256
GO:0071949	FAD binding	9/4142	40/18639	0.225	1.0125	0.544841906189213	0.954392434863156
GO:0140662	ATP-dependent protein folding chaperone	9/4142	40/18639	0.225	1.0125	0.544841906189213	0.954392434863156
GO:1901682	sulfur compound transmembrane transporter activity	14/4142	63/18639	0.222222222222222	1	0.549297931984851	0.960901234119052
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	12/4142	54/18639	0.222222222222222	1	0.55320217996105	0.966428572798713
GO:0042605	peptide antigen binding	10/4142	45/18639	0.222222222222222	1	0.558220636248778	0.973884927218971
GO:0031683	G-protein beta/gamma-subunit complex binding	5/4142	22/18639	0.227272727272727	1.02272727272727	0.560142492900337	0.975926115147164
GO:0008266	poly(U) RNA binding	6/4142	27/18639	0.222222222222222	1	0.574922394724788	0.993115652410932
GO:0016405	CoA-ligase activity	6/4142	27/18639	0.222222222222222	1	0.574922394724788	0.993115652410932
GO:0015175	neutral L-amino acid transmembrane transporter activity	9/4142	41/18639	0.219512195121951	0.98780487804878	0.577567709091051	0.993115652410932
GO:0008035	high-density lipoprotein particle binding	3/4142	13/18639	0.230769230769231	1.03846153846154	0.577659720778316	0.993115652410932
GO:0008253	5'-nucleotidase activity	3/4142	13/18639	0.230769230769231	1.03846153846154	0.577659720778316	0.993115652410932
GO:0019855	calcium channel inhibitor activity	3/4142	13/18639	0.230769230769231	1.03846153846154	0.577659720778316	0.993115652410932
GO:0030955	potassium ion binding	3/4142	13/18639	0.230769230769231	1.03846153846154	0.577659720778316	0.993115652410932
GO:0031432	titin binding	3/4142	13/18639	0.230769230769231	1.03846153846154	0.577659720778316	0.993115652410932
GO:0071714	icosanoid transmembrane transporter activity	3/4142	13/18639	0.230769230769231	1.03846153846154	0.577659720778316	0.993115652410932
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/4142	13/18639	0.230769230769231	1.03846153846154	0.577659720778316	0.993115652410932
GO:0140313	molecular sequestering activity	12/4142	55/18639	0.218181818181818	0.981818181818182	0.581378435449439	0.998186784673772
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	10/4142	46/18639	0.217391304347826	0.978260869565217	0.588890546875262	1
GO:0015172	acidic amino acid transmembrane transporter activity	4/4142	18/18639	0.222222222222222	1	0.591449292132741	1
GO:0017128	phospholipid scramblase activity	4/4142	18/18639	0.222222222222222	1	0.591449292132741	1
GO:0030228	lipoprotein particle receptor activity	4/4142	18/18639	0.222222222222222	1	0.591449292132741	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	4/4142	18/18639	0.222222222222222	1	0.591449292132741	1
GO:1990381	ubiquitin-specific protease binding	4/4142	18/18639	0.222222222222222	1	0.591449292132741	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	19/4142	88/18639	0.215909090909091	0.971590909090909	0.598280988996216	1
GO:0019843	rRNA binding	14/4142	65/18639	0.215384615384615	0.969230769230769	0.601083595340202	1
GO:0140103	catalytic activity, acting on a glycoprotein	5/4142	23/18639	0.217391304347826	0.978260869565217	0.603176760954604	1
GO:0015078	proton transmembrane transporter activity	40/4142	185/18639	0.216216216216216	0.972972972972973	0.60691712393865	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	28/4142	130/18639	0.215384615384615	0.969230769230769	0.608728228021541	1
GO:0016859	cis-trans isomerase activity	9/4142	42/18639	0.214285714285714	0.964285714285714	0.609191390193903	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/4142	28/18639	0.214285714285714	0.964285714285714	0.613549868934582	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	58/4142	268/18639	0.216417910447761	0.973880597014925	0.614847934574241	1
GO:0005200	structural constituent of cytoskeleton	24/4142	112/18639	0.214285714285714	0.964285714285714	0.616921938858421	1
GO:0140311	protein sequestering activity	7/4142	33/18639	0.212121212121212	0.954545454545455	0.622937658364544	1
GO:0008235	metalloexopeptidase activity	14/4142	66/18639	0.212121212121212	0.954545454545455	0.625950920457856	1
GO:0016530	metallochaperone activity	3/4142	14/18639	0.214285714285714	0.964285714285714	0.631614020205582	1
GO:0019992	diacylglycerol binding	3/4142	14/18639	0.214285714285714	0.964285714285714	0.631614020205582	1
GO:0071933	Arp2/3 complex binding	3/4142	14/18639	0.214285714285714	0.964285714285714	0.631614020205582	1
GO:1901474	azole transmembrane transporter activity	3/4142	14/18639	0.214285714285714	0.964285714285714	0.631614020205582	1
GO:1901612	cardiolipin binding	3/4142	14/18639	0.214285714285714	0.964285714285714	0.631614020205582	1
GO:0002020	protease binding	29/4142	136/18639	0.213235294117647	0.959558823529412	0.632941313022628	1
GO:0003756	protein disulfide isomerase activity	4/4142	19/18639	0.210526315789474	0.947368421052632	0.637356709102604	1
GO:0005520	insulin-like growth factor binding	4/4142	19/18639	0.210526315789474	0.947368421052632	0.637356709102604	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/4142	19/18639	0.210526315789474	0.947368421052632	0.637356709102604	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/4142	19/18639	0.210526315789474	0.947368421052632	0.637356709102604	1
GO:0046527	glucosyltransferase activity	4/4142	19/18639	0.210526315789474	0.947368421052632	0.637356709102604	1
GO:0070003	threonine-type peptidase activity	4/4142	19/18639	0.210526315789474	0.947368421052632	0.637356709102604	1
GO:0005315	phosphate transmembrane transporter activity	5/4142	24/18639	0.208333333333333	0.9375	0.643694094218091	1
GO:0030215	semaphorin receptor binding	5/4142	24/18639	0.208333333333333	0.9375	0.643694094218091	1
GO:0016758	hexosyltransferase activity	42/4142	197/18639	0.213197969543147	0.959390862944163	0.647641885380035	1
GO:0004629	phospholipase C activity	6/4142	29/18639	0.206896551724138	0.931034482758621	0.650124113939825	1
GO:0015035	protein-disulfide reductase activity	7/4142	34/18639	0.205882352941176	0.926470588235294	0.65646019690848	1
GO:0016831	carboxy-lyase activity	7/4142	34/18639	0.205882352941176	0.926470588235294	0.65646019690848	1
GO:0005516	calmodulin binding	44/4142	207/18639	0.21256038647343	0.956521739130435	0.65818591456831	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	19/4142	91/18639	0.208791208791209	0.93956043956044	0.661254147214101	1
GO:0005543	phospholipid binding	107/4142	497/18639	0.215291750503018	0.968812877263581	0.664026797642946	1
GO:0035254	glutamate receptor binding	10/4142	49/18639	0.204081632653061	0.918367346938776	0.674382810543094	1
GO:0004467	long-chain fatty acid-CoA ligase activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0004559	alpha-mannosidase activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0005041	low-density lipoprotein particle receptor activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0008242	omega peptidase activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0008252	nucleotidase activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0048531	beta-1,3-galactosyltransferase activity	3/4142	15/18639	0.2	0.9	0.680572175646511	1
GO:0008483	transaminase activity	5/4142	25/18639	0.2	0.9	0.681509401292305	1
GO:0001965	G-protein alpha-subunit binding	6/4142	30/18639	0.2	0.9	0.684496075797185	1
GO:0000182	rDNA binding	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0004382	GDP phosphatase activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0005337	nucleoside transmembrane transporter activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0005345	purine nucleobase transmembrane transporter activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0015187	glycine transmembrane transporter activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0015203	polyamine transmembrane transporter activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0015279	store-operated calcium channel activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0016868	intramolecular phosphotransferase activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0035256	G protein-coupled glutamate receptor binding	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0043295	glutathione binding	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:1990763	arrestin family protein binding	2/4142	10/18639	0.2	0.9	0.687592729001312	1
GO:0008374	O-acyltransferase activity	11/4142	55/18639	0.2	0.9	0.704611186850175	1
GO:0046982	protein heterodimerization activity	78/4142	369/18639	0.211382113821138	0.951219512195122	0.712742158178498	1
GO:0005496	steroid binding	22/4142	108/18639	0.203703703703704	0.916666666666667	0.714212770664098	1
GO:0005112	Notch binding	5/4142	26/18639	0.192307692307692	0.865384615384615	0.716522230890189	1
GO:0005227	calcium-activated cation channel activity	5/4142	26/18639	0.192307692307692	0.865384615384615	0.716522230890189	1
GO:0008143	poly(A) binding	5/4142	26/18639	0.192307692307692	0.865384615384615	0.716522230890189	1
GO:0008198	ferrous iron binding	5/4142	26/18639	0.192307692307692	0.865384615384615	0.716522230890189	1
GO:0047499	calcium-independent phospholipase A2 activity	6/4142	31/18639	0.193548387096774	0.870967741935484	0.716575095881761	1
GO:0004190	aspartic-type endopeptidase activity	7/4142	36/18639	0.194444444444444	0.875	0.717835739935565	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/4142	21/18639	0.19047619047619	0.857142857142857	0.718552807837213	1
GO:0009975	cyclase activity	4/4142	21/18639	0.19047619047619	0.857142857142857	0.718552807837213	1
GO:0019200	carbohydrate kinase activity	4/4142	21/18639	0.19047619047619	0.857142857142857	0.718552807837213	1
GO:1904047	S-adenosyl-L-methionine binding	4/4142	21/18639	0.19047619047619	0.857142857142857	0.718552807837213	1
GO:0004812	aminoacyl-tRNA ligase activity	8/4142	41/18639	0.195121951219512	0.878048780487805	0.71983602577002	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	8/4142	41/18639	0.195121951219512	0.878048780487805	0.71983602577002	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/4142	16/18639	0.1875	0.84375	0.724507970747239	1
GO:0008142	oxysterol binding	3/4142	16/18639	0.1875	0.84375	0.724507970747239	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/4142	16/18639	0.1875	0.84375	0.724507970747239	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/4142	16/18639	0.1875	0.84375	0.724507970747239	1
GO:0001217	DNA-binding transcription repressor activity	58/4142	278/18639	0.20863309352518	0.938848920863309	0.730266324349775	1
GO:0004620	phospholipase activity	22/4142	109/18639	0.201834862385321	0.908256880733945	0.730983227851047	1
GO:0000099	sulfur amino acid transmembrane transporter activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0001851	complement component C3b binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0004016	adenylate cyclase activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0008199	ferric iron binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0010854	adenylate cyclase regulator activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0015205	nucleobase transmembrane transporter activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0015217	ADP transmembrane transporter activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0034056	estrogen response element binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0034713	type I transforming growth factor beta receptor binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0050786	RAGE receptor binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0050998	nitric-oxide synthase binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0070697	activin receptor binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0097493	structural molecule activity conferring elasticity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:1900750	oligopeptide binding	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:1990948	ubiquitin ligase inhibitor activity	2/4142	11/18639	0.181818181818182	0.818181818181818	0.739041257637704	1
GO:0023023	MHC protein complex binding	7/4142	37/18639	0.189189189189189	0.851351351351351	0.745569300734048	1
GO:0070001	aspartic-type peptidase activity	7/4142	37/18639	0.189189189189189	0.851351351351351	0.745569300734048	1
GO:0022884	macromolecule transmembrane transporter activity	6/4142	32/18639	0.1875	0.84375	0.746321761787624	1
GO:0042910	xenobiotic transmembrane transporter activity	6/4142	32/18639	0.1875	0.84375	0.746321761787624	1
GO:0043425	bHLH transcription factor binding	6/4142	32/18639	0.1875	0.84375	0.746321761787624	1
GO:0047498	calcium-dependent phospholipase A2 activity	6/4142	32/18639	0.1875	0.84375	0.746321761787624	1
GO:0071813	lipoprotein particle binding	6/4142	32/18639	0.1875	0.84375	0.746321761787624	1
GO:0071814	protein-lipid complex binding	6/4142	32/18639	0.1875	0.84375	0.746321761787624	1
GO:0050660	flavin adenine dinucleotide binding	17/4142	86/18639	0.197674418604651	0.88953488372093	0.747118115231449	1
GO:0005080	protein kinase C binding	10/4142	52/18639	0.192307692307692	0.865384615384615	0.748376687673267	1
GO:0015252	proton channel activity	5/4142	27/18639	0.185185185185185	0.833333333333333	0.748704011836871	1
GO:0015179	L-amino acid transmembrane transporter activity	12/4142	62/18639	0.193548387096774	0.870967741935484	0.752306301743074	1
GO:0008970	phospholipase A1 activity	4/4142	22/18639	0.181818181818182	0.818181818181818	0.753755100045408	1
GO:0000149	SNARE binding	21/4142	106/18639	0.19811320754717	0.891509433962264	0.759629368341027	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0015278	intracellularly gated calcium channel activity	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0016805	dipeptidase activity	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0019198	transmembrane receptor protein phosphatase activity	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0030169	low-density lipoprotein particle binding	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0031489	myosin V binding	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0045125	bioactive lipid receptor activity	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0070402	NADPH binding	3/4142	17/18639	0.176470588235294	0.794117647058824	0.763560512917916	1
GO:0032266	phosphatidylinositol-3-phosphate binding	9/4142	48/18639	0.1875	0.84375	0.76991041140911	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	10/4142	53/18639	0.188679245283019	0.849056603773585	0.770291579069794	1
GO:0045499	chemorepellent activity	5/4142	28/18639	0.178571428571429	0.803571428571429	0.778085347250412	1
GO:0046625	sphingolipid binding	5/4142	28/18639	0.178571428571429	0.803571428571429	0.778085347250412	1
GO:0051959	dynein light intermediate chain binding	5/4142	28/18639	0.178571428571429	0.803571428571429	0.778085347250412	1
GO:0001540	amyloid-beta binding	16/4142	83/18639	0.192771084337349	0.867469879518072	0.779144194476245	1
GO:0005247	voltage-gated chloride channel activity	2/4142	12/18639	0.166666666666667	0.75	0.7830569818793	1
GO:0005436	sodium:phosphate symporter activity	2/4142	12/18639	0.166666666666667	0.75	0.7830569818793	1
GO:0015166	polyol transmembrane transporter activity	2/4142	12/18639	0.166666666666667	0.75	0.7830569818793	1
GO:0015269	calcium-activated potassium channel activity	2/4142	12/18639	0.166666666666667	0.75	0.7830569818793	1
GO:0070410	co-SMAD binding	2/4142	12/18639	0.166666666666667	0.75	0.7830569818793	1
GO:0017134	fibroblast growth factor binding	4/4142	23/18639	0.173913043478261	0.782608695652174	0.785455803011893	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/4142	23/18639	0.173913043478261	0.782608695652174	0.785455803011893	1
GO:0004879	nuclear receptor activity	11/4142	59/18639	0.186440677966102	0.838983050847458	0.790796198091242	1
GO:0016248	channel inhibitor activity	8/4142	44/18639	0.181818181818182	0.818181818181818	0.792735280429107	1
GO:0017075	syntaxin-1 binding	3/4142	18/18639	0.166666666666667	0.75	0.797982757074951	1
GO:0031690	adrenergic receptor binding	3/4142	18/18639	0.166666666666667	0.75	0.797982757074951	1
GO:0070064	proline-rich region binding	3/4142	18/18639	0.166666666666667	0.75	0.797982757074951	1
GO:0098641	cadherin binding involved in cell-cell adhesion	3/4142	18/18639	0.166666666666667	0.75	0.797982757074951	1
GO:0098531	ligand-modulated transcription factor activity	11/4142	60/18639	0.183333333333333	0.825	0.809203215354566	1
GO:0141110	transporter inhibitor activity	8/4142	45/18639	0.177777777777778	0.8	0.813607375495629	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/4142	24/18639	0.166666666666667	0.75	0.813808144770653	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/4142	24/18639	0.166666666666667	0.75	0.813808144770653	1
GO:0004806	triacylglycerol lipase activity	4/4142	24/18639	0.166666666666667	0.75	0.813808144770653	1
GO:0005542	folic acid binding	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0031994	insulin-like growth factor I binding	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0043560	insulin receptor substrate binding	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0051011	microtubule minus-end binding	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0061459	L-arginine transmembrane transporter activity	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0071837	HMG box domain binding	2/4142	13/18639	0.153846153846154	0.692307692307692	0.820401938443115	1
GO:0004623	phospholipase A2 activity	6/4142	35/18639	0.171428571428571	0.771428571428571	0.821786302382006	1
GO:0016298	lipase activity	25/4142	130/18639	0.192307692307692	0.865384615384615	0.822971856744344	1
GO:0017022	myosin binding	14/4142	76/18639	0.184210526315789	0.828947368421053	0.824920499088742	1
GO:0015245	fatty acid transmembrane transporter activity	3/4142	19/18639	0.157894736842105	0.710526315789474	0.828100141069766	1
GO:0034987	immunoglobulin receptor binding	3/4142	19/18639	0.157894736842105	0.710526315789474	0.828100141069766	1
GO:0097001	ceramide binding	3/4142	19/18639	0.157894736842105	0.710526315789474	0.828100141069766	1
GO:0008013	beta-catenin binding	20/4142	106/18639	0.188679245283019	0.849056603773585	0.828564096868185	1
GO:0001968	fibronectin binding	5/4142	30/18639	0.166666666666667	0.75	0.828793509868704	1
GO:0015215	nucleotide transmembrane transporter activity	5/4142	30/18639	0.166666666666667	0.75	0.828793509868704	1
GO:0022839	monoatomic ion-gated channel activity	5/4142	30/18639	0.166666666666667	0.75	0.828793509868704	1
GO:0016597	amino acid binding	9/4142	51/18639	0.176470588235294	0.794117647058824	0.829874946130765	1
GO:0004180	carboxypeptidase activity	8/4142	46/18639	0.173913043478261	0.782608695652174	0.832829014988541	1
GO:0017080	sodium channel regulator activity	7/4142	41/18639	0.170731707317073	0.768292682926829	0.836929357156013	1
GO:0000030	mannosyltransferase activity	4/4142	25/18639	0.16	0.72	0.839007905433196	1
GO:0015645	fatty acid ligase activity	4/4142	25/18639	0.16	0.72	0.839007905433196	1
GO:0120515	fatty acid-CoA ligase activity	4/4142	25/18639	0.16	0.72	0.839007905433196	1
GO:0052689	carboxylic ester hydrolase activity	17/4142	92/18639	0.184782608695652	0.831521739130435	0.839378360624007	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/4142	36/18639	0.166666666666667	0.75	0.842576414871294	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	23/4142	122/18639	0.188524590163934	0.848360655737705	0.84335700282074	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	25/4142	132/18639	0.189393939393939	0.852272727272727	0.845347245260121	1
GO:0008327	methyl-CpG binding	5/4142	31/18639	0.161290322580645	0.725806451612903	0.850373974096962	1
GO:0070273	phosphatidylinositol-4-phosphate binding	5/4142	31/18639	0.161290322580645	0.725806451612903	0.850373974096962	1
GO:0070325	lipoprotein particle receptor binding	5/4142	31/18639	0.161290322580645	0.725806451612903	0.850373974096962	1
GO:0005504	fatty acid binding	8/4142	47/18639	0.170212765957447	0.765957446808511	0.85045983211394	1
GO:0005161	platelet-derived growth factor receptor binding	2/4142	14/18639	0.142857142857143	0.642857142857143	0.851866591482704	1
GO:0005347	ATP transmembrane transporter activity	2/4142	14/18639	0.142857142857143	0.642857142857143	0.851866591482704	1
GO:0015926	glucosidase activity	2/4142	14/18639	0.142857142857143	0.642857142857143	0.851866591482704	1
GO:0031404	chloride ion binding	2/4142	14/18639	0.142857142857143	0.642857142857143	0.851866591482704	1
GO:0032036	myosin heavy chain binding	2/4142	14/18639	0.142857142857143	0.642857142857143	0.851866591482704	1
GO:0032454	histone H3K9 demethylase activity	2/4142	14/18639	0.142857142857143	0.642857142857143	0.851866591482704	1
GO:0042277	peptide binding	49/4142	249/18639	0.196787148594378	0.885542168674699	0.853235835695424	1
GO:0001972	retinoic acid binding	3/4142	20/18639	0.15	0.675	0.854278402632127	1
GO:0010851	cyclase regulator activity	3/4142	20/18639	0.15	0.675	0.854278402632127	1
GO:0004857	enzyme inhibitor activity	84/4142	416/18639	0.201923076923077	0.908653846153846	0.857355610738056	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/4142	26/18639	0.153846153846154	0.692307692307692	0.861278028077379	1
GO:0050750	low-density lipoprotein particle receptor binding	4/4142	26/18639	0.153846153846154	0.692307692307692	0.861278028077379	1
GO:0030551	cyclic nucleotide binding	6/4142	37/18639	0.162162162162162	0.72972972972973	0.861351985349471	1
GO:0042805	actinin binding	6/4142	37/18639	0.162162162162162	0.72972972972973	0.861351985349471	1
GO:0008200	ion channel inhibitor activity	7/4142	43/18639	0.162790697674419	0.732558139534884	0.871664127780944	1
GO:0015174	basic amino acid transmembrane transporter activity	3/4142	21/18639	0.142857142857143	0.642857142857143	0.876899335097945	1
GO:0048306	calcium-dependent protein binding	14/4142	80/18639	0.175	0.7875	0.877618844075874	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/4142	15/18639	0.133333333333333	0.6	0.878219578534426	1
GO:0010181	FMN binding	2/4142	15/18639	0.133333333333333	0.6	0.878219578534426	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/4142	15/18639	0.133333333333333	0.6	0.878219578534426	1
GO:0031005	filamin binding	2/4142	15/18639	0.133333333333333	0.6	0.878219578534426	1
GO:0033130	acetylcholine receptor binding	2/4142	15/18639	0.133333333333333	0.6	0.878219578534426	1
GO:0051371	muscle alpha-actinin binding	2/4142	15/18639	0.133333333333333	0.6	0.878219578534426	1
GO:0140161	monocarboxylate:sodium symporter activity	2/4142	15/18639	0.133333333333333	0.6	0.878219578534426	1
GO:0000146	microfilament motor activity	6/4142	38/18639	0.157894736842105	0.710526315789474	0.87823436676995	1
GO:0008320	protein transmembrane transporter activity	4/4142	27/18639	0.148148148148148	0.666666666666667	0.880856117858337	1
GO:0038024	cargo receptor activity	11/4142	65/18639	0.169230769230769	0.761538461538462	0.883481612223736	1
GO:1902936	phosphatidylinositol bisphosphate binding	20/4142	111/18639	0.18018018018018	0.810810810810811	0.883611236027116	1
GO:0019956	chemokine binding	5/4142	33/18639	0.151515151515152	0.681818181818182	0.886768339956895	1
GO:0030296	protein tyrosine kinase activator activity	5/4142	33/18639	0.151515151515152	0.681818181818182	0.886768339956895	1
GO:0015377	chloride:monoatomic cation symporter activity	3/4142	22/18639	0.136363636363636	0.613636363636364	0.896343161685188	1
GO:0016881	acid-amino acid ligase activity	3/4142	22/18639	0.136363636363636	0.613636363636364	0.896343161685188	1
GO:0140784	metal ion sensor activity	3/4142	22/18639	0.136363636363636	0.613636363636364	0.896343161685188	1
GO:0008081	phosphoric diester hydrolase activity	15/4142	87/18639	0.172413793103448	0.775862068965517	0.89717386484885	1
GO:0005126	cytokine receptor binding	53/4142	275/18639	0.192727272727273	0.867272727272727	0.897407280134681	1
GO:0019905	syntaxin binding	10/4142	61/18639	0.163934426229508	0.737704918032787	0.89821383320743	1
GO:0008009	chemokine activity	7/4142	45/18639	0.155555555555556	0.7	0.900041998163395	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/4142	16/18639	0.125	0.5625	0.900178379646882	1
GO:0015385	sodium:proton antiporter activity	2/4142	16/18639	0.125	0.5625	0.900178379646882	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/4142	16/18639	0.125	0.5625	0.900178379646882	1
GO:0055102	lipase inhibitor activity	2/4142	16/18639	0.125	0.5625	0.900178379646882	1
GO:0090482	vitamin transmembrane transporter activity	5/4142	34/18639	0.147058823529412	0.661764705882353	0.901922892613171	1
GO:0030170	pyridoxal phosphate binding	9/4142	56/18639	0.160714285714286	0.723214285714286	0.90200012512093	1
GO:0008237	metallopeptidase activity	34/4142	184/18639	0.184782608695652	0.831521739130435	0.908295744837093	1
GO:0070279	vitamin B6 binding	9/4142	57/18639	0.157894736842105	0.710526315789474	0.912819717211485	1
GO:0003785	actin monomer binding	4/4142	29/18639	0.137931034482759	0.620689655172414	0.912903082362784	1
GO:0004181	metallocarboxypeptidase activity	4/4142	29/18639	0.137931034482759	0.620689655172414	0.912903082362784	1
GO:0043236	laminin binding	4/4142	29/18639	0.137931034482759	0.620689655172414	0.912903082362784	1
GO:0004602	glutathione peroxidase activity	3/4142	23/18639	0.130434782608696	0.58695652173913	0.912976265486182	1
GO:0005283	amino acid:sodium symporter activity	3/4142	23/18639	0.130434782608696	0.58695652173913	0.912976265486182	1
GO:0099186	structural constituent of postsynapse	3/4142	23/18639	0.130434782608696	0.58695652173913	0.912976265486182	1
GO:0003735	structural constituent of ribosome	32/4142	175/18639	0.182857142857143	0.822857142857143	0.913954651460815	1
GO:0016229	steroid dehydrogenase activity	5/4142	35/18639	0.142857142857143	0.642857142857143	0.915278990985032	1
GO:0008484	sulfuric ester hydrolase activity	2/4142	17/18639	0.117647058823529	0.529411764705882	0.918394095210744	1
GO:0008569	minus-end-directed microtubule motor activity	2/4142	17/18639	0.117647058823529	0.529411764705882	0.918394095210744	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/4142	17/18639	0.117647058823529	0.529411764705882	0.918394095210744	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/4142	17/18639	0.117647058823529	0.529411764705882	0.918394095210744	1
GO:0045236	CXCR chemokine receptor binding	2/4142	17/18639	0.117647058823529	0.529411764705882	0.918394095210744	1
GO:0001530	lipopolysaccharide binding	6/4142	41/18639	0.146341463414634	0.658536585365854	0.918821081132591	1
GO:0033293	monocarboxylic acid binding	13/4142	79/18639	0.164556962025316	0.740506329113924	0.918947444717768	1
GO:0003796	lysozyme activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0005528	FK506 binding	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0015643	toxic substance binding	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0019911	structural constituent of myelin sheath	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0032052	bile acid binding	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0043121	neurotrophin binding	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0043208	glycosphingolipid binding	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0050308	sugar-phosphatase activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0070097	delta-catenin binding	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0070739	protein-glutamic acid ligase activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0070740	tubulin-glutamic acid ligase activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0141109	transporter activator activity	1/4142	10/18639	0.1	0.45	0.919042774876064	1
GO:0005178	integrin binding	29/4142	161/18639	0.180124223602484	0.81055900621118	0.91984620803861	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/4142	30/18639	0.133333333333333	0.6	0.925843016592642	1
GO:0033612	receptor serine/threonine kinase binding	4/4142	30/18639	0.133333333333333	0.6	0.925843016592642	1
GO:0098918	structural constituent of synapse	4/4142	30/18639	0.133333333333333	0.6	0.925843016592642	1
GO:0004033	aldo-keto reductase (NADPH) activity	5/4142	36/18639	0.138888888888889	0.625	0.927005212938861	1
GO:0045505	dynein intermediate chain binding	5/4142	36/18639	0.138888888888889	0.625	0.927005212938861	1
GO:0015295	solute:proton symporter activity	3/4142	24/18639	0.125	0.5625	0.927143139874115	1
GO:0048027	mRNA 5'-UTR binding	3/4142	24/18639	0.125	0.5625	0.927143139874115	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/4142	24/18639	0.125	0.5625	0.927143139874115	1
GO:0005246	calcium channel regulator activity	8/4142	53/18639	0.150943396226415	0.679245283018868	0.927160275661886	1
GO:0001786	phosphatidylserine binding	9/4142	59/18639	0.152542372881356	0.686440677966102	0.931433764677054	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/4142	86/18639	0.162790697674419	0.732558139534884	0.932109240744613	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	11/4142	70/18639	0.157142857142857	0.707142857142857	0.932325547800142	1
GO:0016782	transferase activity, transferring sulphur-containing groups	11/4142	70/18639	0.157142857142857	0.707142857142857	0.932325547800142	1
GO:0038187	pattern recognition receptor activity	7/4142	48/18639	0.145833333333333	0.65625	0.932510251019087	1
GO:0032393	MHC class I receptor activity	2/4142	18/18639	0.111111111111111	0.5	0.933445512477718	1
GO:0034185	apolipoprotein binding	2/4142	18/18639	0.111111111111111	0.5	0.933445512477718	1
GO:0099602	neurotransmitter receptor regulator activity	2/4142	18/18639	0.111111111111111	0.5	0.933445512477718	1
GO:0001216	DNA-binding transcription activator activity	96/4142	491/18639	0.195519348268839	0.879837067209776	0.934525647996822	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/4142	31/18639	0.129032258064516	0.580645161290323	0.937023615480891	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0019203	carbohydrate phosphatase activity	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0019215	intermediate filament binding	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0019864	IgG binding	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0045294	alpha-catenin binding	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0048185	activin binding	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/4142	11/18639	0.0909090909090909	0.409090909090909	0.9370429265999	1
GO:0022829	wide pore channel activity	5/4142	37/18639	0.135135135135135	0.608108108108108	0.937263529749703	1
GO:0070851	growth factor receptor binding	24/4142	139/18639	0.172661870503597	0.776978417266187	0.938386840851977	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/4142	25/18639	0.12	0.54	0.93916158093424	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	94/4142	484/18639	0.194214876033058	0.87396694214876	0.942043319602367	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	32/4142	181/18639	0.176795580110497	0.795580110497238	0.944575822797109	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/4142	19/18639	0.105263157894737	0.473684210526316	0.945839085584535	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/4142	19/18639	0.105263157894737	0.473684210526316	0.945839085584535	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/4142	19/18639	0.105263157894737	0.473684210526316	0.945839085584535	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/4142	19/18639	0.105263157894737	0.473684210526316	0.945839085584535	1
GO:0042834	peptidoglycan binding	2/4142	19/18639	0.105263157894737	0.473684210526316	0.945839085584535	1
GO:0043395	heparan sulfate proteoglycan binding	2/4142	19/18639	0.105263157894737	0.473684210526316	0.945839085584535	1
GO:0141147	intracellularly calcium-gated channel activity	2/4142	19/18639	0.105263157894737	0.473684210526316	0.945839085584535	1
GO:0005109	frizzled binding	5/4142	38/18639	0.131578947368421	0.592105263157895	0.946207342322393	1
GO:0005518	collagen binding	11/4142	72/18639	0.152777777777778	0.6875	0.946239726199867	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/4142	32/18639	0.125	0.5625	0.946649431649248	1
GO:0048020	CCR chemokine receptor binding	7/4142	50/18639	0.14	0.63	0.948627971163129	1
GO:0015216	purine nucleotide transmembrane transporter activity	3/4142	26/18639	0.115384615384615	0.519230769230769	0.949320305219918	1
GO:0030247	polysaccharide binding	3/4142	26/18639	0.115384615384615	0.519230769230769	0.949320305219918	1
GO:0051139	metal cation:proton antiporter activity	3/4142	26/18639	0.115384615384615	0.519230769230769	0.949320305219918	1
GO:0170055	lipid transmembrane transporter activity	8/4142	56/18639	0.142857142857143	0.642857142857143	0.950635945106121	1
GO:0004000	adenosine deaminase activity	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0004032	aldose reductase (NADPH) activity	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0004859	phospholipase inhibitor activity	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0005527	macrolide binding	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0016208	AMP binding	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0016361	activin receptor activity, type I	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0016362	activin receptor activity, type II	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0017002	activin receptor activity	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0031543	peptidyl-proline dioxygenase activity	1/4142	12/18639	0.0833333333333333	0.375	0.951041648847228	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/4142	20/18639	0.1	0.45	0.95601249480147	1
GO:0031418	L-ascorbic acid binding	2/4142	20/18639	0.1	0.45	0.95601249480147	1
GO:0004364	glutathione transferase activity	3/4142	27/18639	0.111111111111111	0.5	0.957878328640116	1
GO:0023026	MHC class II protein complex binding	3/4142	27/18639	0.111111111111111	0.5	0.957878328640116	1
GO:0005507	copper ion binding	9/4142	63/18639	0.142857142857143	0.642857142857143	0.958564457636962	1
GO:0002161	aminoacyl-tRNA editing activity	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0004465	lipoprotein lipase activity	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0005172	vascular endothelial growth factor receptor binding	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0008417	fucosyltransferase activity	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0017154	semaphorin receptor activity	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0032396	inhibitory MHC class I receptor activity	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0035325	Toll-like receptor binding	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0045159	myosin II binding	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0070700	BMP receptor binding	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0089720	caspase binding	1/4142	13/18639	0.0769230769230769	0.346153846153846	0.961928291380904	1
GO:0051427	hormone receptor binding	4/4142	34/18639	0.117647058823529	0.529411764705882	0.961973692566886	1
GO:0001846	opsonin binding	2/4142	21/18639	0.0952380952380952	0.428571428571429	0.964340195822893	1
GO:0010314	phosphatidylinositol-5-phosphate binding	2/4142	21/18639	0.0952380952380952	0.428571428571429	0.964340195822893	1
GO:0015125	bile acid transmembrane transporter activity	2/4142	21/18639	0.0952380952380952	0.428571428571429	0.964340195822893	1
GO:0061891	calcium ion sensor activity	2/4142	21/18639	0.0952380952380952	0.428571428571429	0.964340195822893	1
GO:0005253	monoatomic anion channel activity	16/4142	103/18639	0.155339805825243	0.699029126213592	0.964987637773234	1
GO:0050698	proteoglycan sulfotransferase activity	3/4142	28/18639	0.107142857142857	0.482142857142857	0.965065578521771	1
GO:0051393	alpha-actinin binding	3/4142	28/18639	0.107142857142857	0.482142857142857	0.965065578521771	1
GO:0005544	calcium-dependent phospholipid binding	7/4142	53/18639	0.132075471698113	0.594339622641509	0.96639650653608	1
GO:0015459	potassium channel regulator activity	8/4142	59/18639	0.135593220338983	0.610169491525424	0.967121638407078	1
GO:0070888	E-box binding	8/4142	59/18639	0.135593220338983	0.610169491525424	0.967121638407078	1
GO:0005343	organic acid:sodium symporter activity	4/4142	35/18639	0.114285714285714	0.514285714285714	0.967998815351641	1
GO:0004065	arylsulfatase activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0005313	L-glutamate transmembrane transporter activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0008191	metalloendopeptidase inhibitor activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0008195	phosphatidate phosphatase activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0008494	translation activator activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0015386	potassium:proton antiporter activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0019763	immunoglobulin receptor activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0042813	Wnt receptor activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0061783	peptidoglycan muralytic activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0098821	BMP receptor activity	1/4142	14/18639	0.0714285714285714	0.321428571428571	0.970394575988457	1
GO:0004222	metalloendopeptidase activity	17/4142	110/18639	0.154545454545455	0.695454545454545	0.970472111121062	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/4142	29/18639	0.103448275862069	0.46551724137931	0.971084328078577	1
GO:0099604	ligand-gated calcium channel activity	3/4142	29/18639	0.103448275862069	0.46551724137931	0.971084328078577	1
GO:0008093	cytoskeletal anchor activity	2/4142	22/18639	0.0909090909090909	0.409090909090909	0.971139899236664	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/4142	22/18639	0.0909090909090909	0.409090909090909	0.971139899236664	1
GO:0033691	sialic acid binding	2/4142	22/18639	0.0909090909090909	0.409090909090909	0.971139899236664	1
GO:0030165	PDZ domain binding	12/4142	83/18639	0.144578313253012	0.650602409638554	0.971995165789902	1
GO:0042379	chemokine receptor binding	10/4142	72/18639	0.138888888888889	0.625	0.973058209337915	1
GO:0098632	cell-cell adhesion mediator activity	7/4142	55/18639	0.127272727272727	0.572727272727273	0.974914368425038	1
GO:0022804	active transmembrane transporter activity	85/4142	457/18639	0.185995623632385	0.836980306345733	0.975794874751896	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/4142	30/18639	0.1	0.45	0.976111140465903	1
GO:0000295	adenine nucleotide transmembrane transporter activity	2/4142	23/18639	0.0869565217391304	0.391304347826087	0.976679292927186	1
GO:0016493	C-C chemokine receptor activity	2/4142	23/18639	0.0869565217391304	0.391304347826087	0.976679292927186	1
GO:0031681	G-protein beta-subunit binding	2/4142	23/18639	0.0869565217391304	0.391304347826087	0.976679292927186	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/4142	15/18639	0.0666666666666667	0.3	0.976978504378031	1
GO:0005523	tropomyosin binding	1/4142	15/18639	0.0666666666666667	0.3	0.976978504378031	1
GO:0015116	sulfate transmembrane transporter activity	1/4142	15/18639	0.0666666666666667	0.3	0.976978504378031	1
GO:0017081	chloride channel regulator activity	1/4142	15/18639	0.0666666666666667	0.3	0.976978504378031	1
GO:0034483	heparan sulfate sulfotransferase activity	1/4142	15/18639	0.0666666666666667	0.3	0.976978504378031	1
GO:0004175	endopeptidase activity	74/4142	405/18639	0.182716049382716	0.822222222222222	0.978790008325387	1
GO:0072341	modified amino acid binding	13/4142	91/18639	0.142857142857143	0.642857142857143	0.979061718778159	1
GO:0005540	hyaluronic acid binding	2/4142	24/18639	0.0833333333333333	0.375	0.981182579568374	1
GO:0015149	hexose transmembrane transporter activity	2/4142	24/18639	0.0833333333333333	0.375	0.981182579568374	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/4142	24/18639	0.0833333333333333	0.375	0.981182579568374	1
GO:0019957	C-C chemokine binding	2/4142	24/18639	0.0833333333333333	0.375	0.981182579568374	1
GO:0050431	transforming growth factor beta binding	2/4142	24/18639	0.0833333333333333	0.375	0.981182579568374	1
GO:0055056	D-glucose transmembrane transporter activity	2/4142	24/18639	0.0833333333333333	0.375	0.981182579568374	1
GO:0016247	channel regulator activity	27/4142	168/18639	0.160714285714286	0.723214285714286	0.981316694006343	1
GO:0061135	endopeptidase regulator activity	30/4142	184/18639	0.16304347826087	0.733695652173913	0.9816569582426	1
GO:0005024	transforming growth factor beta receptor activity	1/4142	16/18639	0.0625	0.28125	0.982098512693441	1
GO:0005149	interleukin-1 receptor binding	1/4142	16/18639	0.0625	0.28125	0.982098512693441	1
GO:0015378	sodium:chloride symporter activity	1/4142	16/18639	0.0625	0.28125	0.982098512693441	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/4142	16/18639	0.0625	0.28125	0.982098512693441	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/4142	16/18639	0.0625	0.28125	0.982098512693441	1
GO:0015106	bicarbonate transmembrane transporter activity	3/4142	32/18639	0.09375	0.421875	0.983780088666839	1
GO:0098631	cell adhesion mediator activity	10/4142	76/18639	0.131578947368421	0.592105263157895	0.984194827249223	1
GO:0141108	transporter regulator activity	27/4142	170/18639	0.158823529411765	0.714705882352941	0.984537231148966	1
GO:0001848	complement binding	2/4142	25/18639	0.08	0.36	0.984836579449603	1
GO:0005537	D-mannose binding	2/4142	25/18639	0.08	0.36	0.984836579449603	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/4142	25/18639	0.08	0.36	0.984836579449603	1
GO:0099106	ion channel regulator activity	25/4142	160/18639	0.15625	0.703125	0.985515625847646	1
GO:0009881	photoreceptor activity	1/4142	17/18639	0.0588235294117647	0.264705882352941	0.98608003878611	1
GO:0030548	acetylcholine receptor regulator activity	1/4142	17/18639	0.0588235294117647	0.264705882352941	0.98608003878611	1
GO:0036041	long-chain fatty acid binding	1/4142	17/18639	0.0588235294117647	0.264705882352941	0.98608003878611	1
GO:0046943	carboxylic acid transmembrane transporter activity	30/4142	188/18639	0.159574468085106	0.718085106382979	0.987294531161886	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/4142	26/18639	0.0769230769230769	0.346153846153846	0.987796268968744	1
GO:0004950	chemokine receptor activity	2/4142	26/18639	0.0769230769230769	0.346153846153846	0.987796268968744	1
GO:0015145	monosaccharide transmembrane transporter activity	2/4142	26/18639	0.0769230769230769	0.346153846153846	0.987796268968744	1
GO:0030507	spectrin binding	2/4142	26/18639	0.0769230769230769	0.346153846153846	0.987796268968744	1
GO:0005342	organic acid transmembrane transporter activity	30/4142	189/18639	0.158730158730159	0.714285714285714	0.988433244827886	1
GO:0061134	peptidase regulator activity	37/4142	226/18639	0.163716814159292	0.736725663716814	0.988556699359278	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/4142	34/18639	0.0882352941176471	0.397058823529412	0.989056903344942	1
GO:0015171	amino acid transmembrane transporter activity	14/4142	102/18639	0.137254901960784	0.617647058823529	0.989155936059124	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/4142	18/18639	0.0555555555555556	0.25	0.989176187392486	1
GO:0015373	monoatomic anion:sodium symporter activity	1/4142	18/18639	0.0555555555555556	0.25	0.989176187392486	1
GO:0016854	racemase and epimerase activity	1/4142	18/18639	0.0555555555555556	0.25	0.989176187392486	1
GO:0008514	organic anion transmembrane transporter activity	45/4142	269/18639	0.16728624535316	0.752788104089219	0.989831903871693	1
GO:0035255	ionotropic glutamate receptor binding	2/4142	27/18639	0.0740740740740741	0.333333333333333	0.990189704195034	1
GO:0008307	structural constituent of muscle	4/4142	42/18639	0.0952380952380952	0.428571428571429	0.990910039256629	1
GO:0042056	chemoattractant activity	4/4142	42/18639	0.0952380952380952	0.428571428571429	0.990910039256629	1
GO:0048029	monosaccharide binding	9/4142	74/18639	0.121621621621622	0.547297297297297	0.99097038196133	1
GO:0022821	solute:potassium antiporter activity	1/4142	19/18639	0.0526315789473684	0.236842105263158	0.991583804159594	1
GO:0030506	ankyrin binding	1/4142	19/18639	0.0526315789473684	0.236842105263158	0.991583804159594	1
GO:0042577	lipid phosphatase activity	1/4142	19/18639	0.0526315789473684	0.236842105263158	0.991583804159594	1
GO:0051119	sugar transmembrane transporter activity	2/4142	28/18639	0.0714285714285714	0.321428571428571	0.992122329246824	1
GO:0015294	solute:monoatomic cation symporter activity	16/4142	116/18639	0.137931034482759	0.620689655172414	0.992134440502123	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/4142	20/18639	0.05	0.225	0.993455978336337	1
GO:0015464	acetylcholine receptor activity	1/4142	20/18639	0.05	0.225	0.993455978336337	1
GO:0016408	C-acyltransferase activity	1/4142	20/18639	0.05	0.225	0.993455978336337	1
GO:0030627	pre-mRNA 5'-splice site binding	1/4142	20/18639	0.05	0.225	0.993455978336337	1
GO:0043394	proteoglycan binding	3/4142	37/18639	0.0810810810810811	0.364864864864865	0.993999355504103	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/4142	52/18639	0.0961538461538462	0.432692307692308	0.994887626120838	1
GO:0051428	peptide hormone receptor binding	1/4142	21/18639	0.0476190476190476	0.214285714285714	0.99491176746201	1
GO:0005501	retinoid binding	3/4142	38/18639	0.0789473684210526	0.355263157894737	0.995100940116452	1
GO:0019840	isoprenoid binding	3/4142	38/18639	0.0789473684210526	0.355263157894737	0.995100940116452	1
GO:0008509	monoatomic anion transmembrane transporter activity	21/4142	149/18639	0.140939597315436	0.634228187919463	0.995520047009557	1
GO:0015370	solute:sodium symporter activity	9/4142	79/18639	0.113924050632911	0.512658227848101	0.995732385489752	1
GO:0005452	solute:inorganic anion antiporter activity	2/4142	31/18639	0.0645161290322581	0.290322580645161	0.99594508743791	1
GO:0019842	vitamin binding	21/4142	150/18639	0.14	0.63	0.996011848246215	1
GO:0015026	coreceptor activity	6/4142	61/18639	0.0983606557377049	0.442622950819672	0.996563249775687	1
GO:0015293	symporter activity	20/4142	146/18639	0.136986301369863	0.616438356164384	0.99672568254751	1
GO:0015297	antiporter activity	18/4142	135/18639	0.133333333333333	0.6	0.996905131239161	1
GO:0005212	structural constituent of eye lens	1/4142	23/18639	0.0434782608695652	0.195652173913043	0.996923964289746	1
GO:0033218	amide binding	38/4142	247/18639	0.153846153846154	0.692307692307692	0.997301940469995	1
GO:0031406	carboxylic acid binding	27/4142	187/18639	0.144385026737968	0.649732620320856	0.997304096576664	1
GO:0140828	metal cation:monoatomic cation antiporter activity	3/4142	41/18639	0.0731707317073171	0.329268292682927	0.997352162003596	1
GO:0042923	neuropeptide binding	2/4142	33/18639	0.0606060606060606	0.272727272727273	0.997406982780478	1
GO:0005506	iron ion binding	21/4142	154/18639	0.136363636363636	0.613636363636364	0.997517263804141	1
GO:0043177	organic acid binding	27/4142	189/18639	0.142857142857143	0.642857142857143	0.997838096593763	1
GO:0004896	cytokine receptor activity	11/4142	96/18639	0.114583333333333	0.515625	0.99785739046956	1
GO:0005245	voltage-gated calcium channel activity	3/4142	43/18639	0.0697674418604651	0.313953488372093	0.998252230161549	1
GO:0019865	immunoglobulin binding	1/4142	26/18639	0.0384615384615385	0.173076923076923	0.99855430081297	1
GO:0015103	inorganic anion transmembrane transporter activity	22/4142	165/18639	0.133333333333333	0.6	0.9986910608049	1
GO:0050840	extracellular matrix binding	6/4142	67/18639	0.0895522388059701	0.402985074626866	0.998810574356891	1
GO:0005044	scavenger receptor activity	1/4142	27/18639	0.037037037037037	0.166666666666667	0.998876016067506	1
GO:0008395	steroid hydroxylase activity	1/4142	27/18639	0.037037037037037	0.166666666666667	0.998876016067506	1
GO:0008146	sulfotransferase activity	4/4142	53/18639	0.0754716981132075	0.339622641509434	0.99890489428379	1
GO:0030280	structural constituent of skin epidermis	2/4142	37/18639	0.0540540540540541	0.243243243243243	0.998949035928965	1
GO:0019955	cytokine binding	18/4142	144/18639	0.125	0.5625	0.999031026779161	1
GO:0140375	immune receptor activity	20/4142	156/18639	0.128205128205128	0.576923076923077	0.999057316053452	1
GO:0005254	chloride channel activity	8/4142	83/18639	0.0963855421686747	0.433734939759036	0.999212774028428	1
GO:0015144	carbohydrate transmembrane transporter activity	2/4142	40/18639	0.05	0.225	0.999469705284758	1
GO:0048019	receptor antagonist activity	1/4142	30/18639	0.0333333333333333	0.15	0.999471838762307	1
GO:0004497	monooxygenase activity	11/4142	106/18639	0.10377358490566	0.466981132075472	0.999540561135343	1
GO:0005184	neuropeptide hormone activity	1/4142	31/18639	0.032258064516129	0.145161290322581	0.999589397139787	1
GO:0017147	Wnt-protein binding	1/4142	31/18639	0.032258064516129	0.145161290322581	0.999589397139787	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	4/4142	59/18639	0.0677966101694915	0.305084745762712	0.999672379061018	1
GO:0015108	chloride transmembrane transporter activity	13/4142	121/18639	0.107438016528926	0.483471074380165	0.999673566742169	1
GO:0160041	neuropeptide activity	1/4142	32/18639	0.03125	0.140625	0.999680794229587	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/4142	44/18639	0.0454545454545455	0.204545454545455	0.999788575599035	1
GO:0030547	signaling receptor inhibitor activity	2/4142	44/18639	0.0454545454545455	0.204545454545455	0.999788575599035	1
GO:0015020	glucuronosyltransferase activity	1/4142	34/18639	0.0294117647058824	0.132352941176471	0.999807092900771	1
GO:0019825	oxygen binding	1/4142	34/18639	0.0294117647058824	0.132352941176471	0.999807092900771	1
GO:0030246	carbohydrate binding	39/4142	280/18639	0.139285714285714	0.626785714285714	0.99984788149222	1
GO:0046906	tetrapyrrole binding	17/4142	152/18639	0.111842105263158	0.503289473684211	0.999864262250064	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/4142	46/18639	0.0434782608695652	0.195652173913043	0.999866879990364	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/4142	36/18639	0.0277777777777778	0.125	0.999883426738136	1
GO:0042562	hormone binding	8/4142	94/18639	0.0851063829787234	0.382978723404255	0.9998846135279	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/4142	47/18639	0.0425531914893617	0.191489361702128	0.999894437950289	1
GO:0004866	endopeptidase inhibitor activity	18/4142	161/18639	0.111801242236025	0.503105590062112	0.999909504375357	1
GO:0004601	peroxidase activity	3/4142	57/18639	0.0526315789473684	0.236842105263158	0.99991287302132	1
GO:0019838	growth factor binding	14/4142	136/18639	0.102941176470588	0.463235294117647	0.999913778841039	1
GO:0017171	serine hydrolase activity	24/4142	198/18639	0.121212121212121	0.545454545454546	0.99991465544025	1
GO:0008188	neuropeptide receptor activity	2/4142	48/18639	0.0416666666666667	0.1875	0.999916325086097	1
GO:0015291	secondary active transmembrane transporter activity	39/4142	287/18639	0.13588850174216	0.611498257839721	0.999931314498381	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/4142	60/18639	0.05	0.225	0.999954924375613	1
GO:0071855	neuropeptide receptor binding	1/4142	40/18639	0.025	0.1125	0.999957438180767	1
GO:0005010	insulin-like growth factor receptor activity	2/4142	51/18639	0.0392156862745098	0.176470588235294	0.999958422416345	1
GO:0020037	heme binding	14/4142	142/18639	0.0985915492957746	0.443661971830986	0.999966706006276	1
GO:0016209	antioxidant activity	6/4142	86/18639	0.0697674418604651	0.313953488372093	0.999966882438921	1
GO:0008236	serine-type peptidase activity	22/4142	194/18639	0.11340206185567	0.510309278350515	0.999972321946676	1
GO:0030414	peptidase inhibitor activity	18/4142	169/18639	0.106508875739645	0.479289940828402	0.999972350639442	1
GO:0003730	mRNA 3'-UTR binding	33/4142	262/18639	0.125954198473282	0.566793893129771	0.999978607715958	1
GO:0001664	G protein-coupled receptor binding	39/4142	297/18639	0.131313131313131	0.590909090909091	0.999978856169774	1
GO:0016500	protein-hormone receptor activity	3/4142	67/18639	0.0447761194029851	0.201492537313433	0.9999904808869	1
GO:0005262	calcium channel activity	11/4142	131/18639	0.083969465648855	0.377862595419847	0.999993135388301	1
GO:0019199	transmembrane receptor protein kinase activity	4/4142	78/18639	0.0512820512820513	0.230769230769231	0.99999393066465	1
GO:0003823	antigen binding	17/4142	174/18639	0.0977011494252874	0.439655172413793	0.999995338398046	1
GO:0005006	epidermal growth factor receptor activity	1/4142	50/18639	0.02	0.09	0.999996575439199	1
GO:0005030	neurotrophin receptor activity	1/4142	51/18639	0.0196078431372549	0.0882352941176471	0.999997338499656	1
GO:1901681	sulfur compound binding	32/4142	275/18639	0.116363636363636	0.523636363636364	0.999998252130804	1
GO:0017046	peptide hormone binding	1/4142	53/18639	0.0188679245283019	0.0849056603773585	0.999998392504668	1
GO:0038064	collagen receptor activity	1/4142	53/18639	0.0188679245283019	0.0849056603773585	0.999998392504668	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/4142	53/18639	0.0188679245283019	0.0849056603773585	0.999998392504668	1
GO:0015085	calcium ion transmembrane transporter activity	12/4142	147/18639	0.0816326530612245	0.36734693877551	0.999998589857224	1
GO:0004252	serine-type endopeptidase activity	16/4142	176/18639	0.0909090909090909	0.409090909090909	0.999998870308816	1
GO:0015081	sodium ion transmembrane transporter activity	14/4142	164/18639	0.0853658536585366	0.384146341463415	0.999999158476595	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/4142	56/18639	0.0178571428571429	0.0803571428571429	0.999999245543409	1
GO:0005244	voltage-gated monoatomic ion channel activity	15/4142	173/18639	0.0867052023121387	0.390173410404624	0.99999941027209	1
GO:0022832	voltage-gated channel activity	15/4142	175/18639	0.0857142857142857	0.385714285714286	0.999999581826712	1
GO:0099094	ligand-gated monoatomic cation channel activity	9/4142	136/18639	0.0661764705882353	0.297794117647059	0.999999824522411	1
GO:0004867	serine-type endopeptidase inhibitor activity	4/4142	95/18639	0.0421052631578947	0.189473684210526	0.999999852757496	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/4142	63/18639	0.0158730158730159	0.0714285714285714	0.999999870918638	1
GO:0022835	transmitter-gated channel activity	1/4142	63/18639	0.0158730158730159	0.0714285714285714	0.999999870918638	1
GO:0005179	hormone activity	8/4142	132/18639	0.0606060606060606	0.272727272727273	0.999999918264085	1
GO:0005125	cytokine activity	22/4142	234/18639	0.094017094017094	0.423076923076923	0.999999938435197	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/4142	69/18639	0.0144927536231884	0.0652173913043478	0.99999997159663	1
GO:0008083	growth factor activity	11/4142	162/18639	0.0679012345679012	0.305555555555556	0.999999977440177	1
GO:0008528	G protein-coupled peptide receptor activity	6/4142	122/18639	0.0491803278688525	0.221311475409836	0.999999979356466	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/4142	73/18639	0.0136986301369863	0.0616438356164384	0.999999989650806	1
GO:0022843	voltage-gated monoatomic cation channel activity	8/4142	143/18639	0.0559440559440559	0.251748251748252	0.999999991186575	1
GO:0005249	voltage-gated potassium channel activity	3/4142	98/18639	0.0306122448979592	0.137755102040816	0.999999992098563	1
GO:0015079	potassium ion transmembrane transporter activity	10/4142	160/18639	0.0625	0.28125	0.999999992623735	1
GO:0005201	extracellular matrix structural constituent	11/4142	168/18639	0.0654761904761905	0.294642857142857	0.999999992894751	1
GO:0001653	peptide receptor activity	6/4142	128/18639	0.046875	0.2109375	0.999999994266839	1
GO:0008201	heparin binding	11/4142	172/18639	0.063953488372093	0.287790697674419	0.999999996735185	1
GO:0005267	potassium channel activity	5/4142	124/18639	0.0403225806451613	0.181451612903226	0.999999998110833	1
GO:0030527	structural constituent of chromatin	2/4142	98/18639	0.0204081632653061	0.0918367346938775	0.999999999453882	1
GO:0022834	ligand-gated channel activity	11/4142	188/18639	0.0585106382978723	0.263297872340426	0.999999999862105	1
GO:0015276	ligand-gated monoatomic ion channel activity	10/4142	186/18639	0.0537634408602151	0.241935483870968	0.9999999999607	1
GO:0030594	neurotransmitter receptor activity	1/4142	97/18639	0.0103092783505155	0.0463917525773196	0.999999999975908	1
GO:0046873	metal ion transmembrane transporter activity	47/4142	450/18639	0.104444444444444	0.47	0.999999999986061	1
GO:0005539	glycosaminoglycan binding	16/4142	242/18639	0.0661157024793388	0.297520661157025	0.999999999992364	1
GO:0022836	gated channel activity	24/4142	318/18639	0.0754716981132075	0.339622641509434	0.999999999999647	1
GO:0005216	monoatomic ion channel activity	42/4142	448/18639	0.09375	0.421875	0.999999999999873	1
GO:0005261	monoatomic cation channel activity	25/4142	341/18639	0.0733137829912024	0.329912023460411	0.99999999999998	1
GO:0030371	translation repressor activity	10/4142	329/18639	0.0303951367781155	0.13677811550152	1	1
GO:0045182	translation regulator activity	12/4142	356/18639	0.0337078651685393	0.151685393258427	1	1