ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0060589	nucleoside-triphosphatase regulator activity	142/3537	490/18639	0.289795918367347	1.52714337643454	3.74839524319242e-08	3.97986198649537e-05
GO:0030695	GTPase regulator activity	141/3537	489/18639	0.288343558282209	1.51948984529887	5.85704486607118e-08	3.97986198649537e-05
GO:0005096	GTPase activator activity	82/3537	271/18639	0.302583025830258	1.59452785367548	4.60448674246993e-06	0.00208583249433888
GO:0016791	phosphatase activity	81/3537	273/18639	0.296703296703297	1.56354332690211	1.17949636815484e-05	0.00400733891080608
GO:0031267	small GTPase binding	82/3537	283/18639	0.289752650176678	1.52691536518041	2.70868034300239e-05	0.00698444454555981
GO:0016757	glycosyltransferase activity	78/3537	267/18639	0.292134831460674	1.53946879377877	3.08363997596459e-05	0.00698444454555981
GO:0042578	phosphoric ester hydrolase activity	100/3537	363/18639	0.275482093663912	1.45171352666148	3.75149736696892e-05	0.00728326417387251
GO:0052866	phosphatidylinositol phosphate phosphatase activity	17/3537	34/18639	0.5	2.63486005089059	4.3769110892843e-05	0.0074352777129217
GO:0043548	phosphatidylinositol 3-kinase binding	14/3537	26/18639	0.538461538461538	2.83754159326678	7.32025575070639e-05	0.0110535861835667
GO:0005085	guanyl-nucleotide exchange factor activity	67/3537	230/18639	0.291304347826087	1.53509237747538	0.000118207277397596	0.0155087824581478
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	14/3537	27/18639	0.518518518518518	2.73244746018283	0.000125530983840784	0.0155087824581478
GO:0071933	Arp2/3 complex binding	9/3537	14/18639	0.642857142857143	3.3876772082879	0.000249981599603243	0.0283104161550672
GO:0051020	GTPase binding	85/3537	315/18639	0.26984126984127	1.4219879639727	0.000290714938354805	0.03039089240186
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	10/3537	17/18639	0.588235294117647	3.09983535398892	0.000313078068986526	0.0303909354109063
GO:0004721	phosphoprotein phosphatase activity	52/3537	175/18639	0.297142857142857	1.56585968738641	0.000385068006832256	0.0337035784035318
GO:0005049	nuclear export signal receptor activity	8/3537	12/18639	0.666666666666667	3.51314673452078	0.000396804455082052	0.0337035784035318
GO:0001965	G-protein alpha-subunit binding	14/3537	30/18639	0.466666666666667	2.45920271416455	0.000513091315649338	0.04101712340985
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	10/3537	18/18639	0.555555555555556	2.92762227876732	0.000584743718906578	0.0440254551772311
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	7/3537	10/18639	0.7	3.68880407124682	0.000615514090042231	0.0440254551772311
GO:0000149	SNARE binding	34/3537	106/18639	0.320754716981132	1.6902875798166	0.00086935802969733	0.0590728781179335
GO:0030276	clathrin binding	18/3537	46/18639	0.391304347826087	2.0620643876535	0.00116948735998858	0.0756825391535465
GO:0015101	organic cation transmembrane transporter activity	27/3537	81/18639	0.333333333333333	1.75657336726039	0.00150524184983499	0.0929828942693523
GO:0017124	SH3 domain binding	35/3537	115/18639	0.304347826086957	1.60382785706383	0.00205582684737671	0.121472551547172
GO:0003725	double-stranded RNA binding	25/3537	75/18639	0.333333333333333	1.75657336726039	0.00221043299470825	0.125165768325355
GO:0016758	hexosyltransferase activity	54/3537	197/18639	0.274111675126904	1.44449180454915	0.00234973697904672	0.12773170218098
GO:0031625	ubiquitin protein ligase binding	77/3537	302/18639	0.254966887417219	1.34360413191109	0.00298194051066786	0.14260938868764
GO:0015631	tubulin binding	95/3537	385/18639	0.246753246753247	1.30032054459535	0.00309784876123455	0.14260938868764
GO:0019905	syntaxin binding	21/3537	61/18639	0.344262295081967	1.81416593667876	0.00311592438538986	0.14260938868764
GO:0045499	chemorepellent activity	12/3537	28/18639	0.428571428571429	2.25845147219193	0.00313513097664047	0.14260938868764
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	28/3537	89/18639	0.314606741573034	1.65788947022329	0.00325304712974012	0.14260938868764
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	28/3537	89/18639	0.314606741573034	1.65788947022329	0.00325304712974012	0.14260938868764
GO:0044389	ubiquitin-like protein ligase binding	81/3537	322/18639	0.251552795031056	1.32561282063439	0.00349340553234594	0.148360566201817
GO:0004725	protein tyrosine phosphatase activity	30/3537	98/18639	0.306122448979592	1.61317962299424	0.00374692458494893	0.150763976374357
GO:0140789	histone phosphatase activity	39/3537	136/18639	0.286764705882353	1.5111697350696	0.00385999726103623	0.150763976374357
GO:0140793	histone H2AXY142 phosphatase activity	28/3537	90/18639	0.311111111111111	1.6394684761097	0.0038828102819003	0.150763976374357
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	6/3537	10/18639	0.6	3.1618320610687	0.00483223464778672	0.168545935413081
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	8/3537	16/18639	0.5	2.63486005089059	0.00499399654687175	0.168545935413081
GO:0008017	microtubule binding	70/3537	276/18639	0.253623188405797	1.33652321421986	0.00510974293445755	0.168545935413081
GO:0005338	nucleotide-sugar transmembrane transporter activity	7/3537	13/18639	0.538461538461538	2.83754159326678	0.00515004011324158	0.168545935413081
GO:0061459	L-arginine transmembrane transporter activity	7/3537	13/18639	0.538461538461538	2.83754159326678	0.00515004011324158	0.168545935413081
GO:0003779	actin binding	106/3537	443/18639	0.239277652370203	1.26092625460227	0.005153868223324	0.168545935413081
GO:0052742	phosphatidylinositol kinase activity	11/3537	26/18639	0.423076923076923	2.22949696613819	0.00520892515625416	0.168545935413081
GO:0032934	sterol binding	22/3537	68/18639	0.323529411764706	1.70490944469391	0.00590661921294936	0.182583843107189
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	10/3537	23/18639	0.434782608695652	2.29118265294834	0.00606608526108372	0.182583843107189
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/3537	23/18639	0.434782608695652	2.29118265294834	0.00606608526108372	0.182583843107189
GO:0001727	lipid kinase activity	15/3537	41/18639	0.365853658536585	1.92794637870043	0.00618017423320874	0.182583843107189
GO:0016779	nucleotidyltransferase activity	38/3537	136/18639	0.279411764705882	1.47242179314474	0.00686141480320046	0.198397079096796
GO:0043539	protein serine/threonine kinase activator activity	23/3537	73/18639	0.315068493150685	1.66032277179407	0.00708201358738135	0.200509509692734
GO:0038191	neuropilin binding	8/3537	17/18639	0.470588235294118	2.47986828319114	0.00788019525112165	0.21855480298519
GO:0019199	transmembrane receptor protein kinase activity	24/3537	78/18639	0.307692307692308	1.62145233900959	0.00831503717392448	0.220934443947793
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	7/3537	14/18639	0.5	2.63486005089059	0.00862719635560342	0.220934443947793
GO:0030215	semaphorin receptor binding	10/3537	24/18639	0.416666666666667	2.19571670907549	0.00865608142743032	0.220934443947793
GO:0015485	cholesterol binding	18/3537	54/18639	0.333333333333333	1.75657336726039	0.00866754583825896	0.220934443947793
GO:0048185	activin binding	6/3537	11/18639	0.545454545454545	2.87439278278973	0.00893319854155404	0.220934443947793
GO:0019207	kinase regulator activity	71/3537	287/18639	0.247386759581882	1.30365897988315	0.00894142341216232	0.220934443947793
GO:0043130	ubiquitin binding	29/3537	100/18639	0.29	1.52821882951654	0.00983833728506918	0.234623456034671
GO:0030295	protein kinase activator activity	38/3537	139/18639	0.273381294964029	1.44064290552291	0.00998325305421986	0.234623456034671
GO:0008375	acetylglucosaminyltransferase activity	15/3537	43/18639	0.348837209302326	1.83827445410971	0.0101189900983833	0.234623456034671
GO:0008373	sialyltransferase activity	9/3537	21/18639	0.428571428571429	2.25845147219193	0.0101860072892168	0.234623456034671
GO:0005543	phospholipid binding	115/3537	497/18639	0.231388329979879	1.21935173381254	0.0108672559393839	0.246006577323566
GO:0140142	nucleocytoplasmic carrier activity	12/3537	32/18639	0.375	1.97614503816794	0.0110422378342439	0.246006577323566
GO:0000030	mannosyltransferase activity	10/3537	25/18639	0.4	2.10788804071247	0.012014909225042	0.259178756140191
GO:0017056	structural constituent of nuclear pore	10/3537	25/18639	0.4	2.10788804071247	0.012014909225042	0.259178756140191
GO:0008013	beta-catenin binding	30/3537	106/18639	0.283018867924528	1.49143021748524	0.0125319870683529	0.264858117578224
GO:0003712	transcription coregulator activity	114/3537	495/18639	0.23030303030303	1.213632508289	0.0128574415905628	0.264858117578224
GO:0004714	transmembrane receptor protein tyrosine kinase activity	19/3537	60/18639	0.316666666666667	1.66874469889737	0.012862866637353	0.264858117578224
GO:0019887	protein kinase regulator activity	63/3537	255/18639	0.247058823529412	1.30193084867535	0.013527346426815	0.274383041702114
GO:0140035	ubiquitin-like protein reader activity	9/3537	22/18639	0.409090909090909	2.1557945870923	0.0143848169092391	0.275959420651641
GO:0045295	gamma-catenin binding	6/3537	12/18639	0.5	2.63486005089059	0.0150264879530695	0.275959420651641
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	6/3537	12/18639	0.5	2.63486005089059	0.0150264879530695	0.275959420651641
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/3537	12/18639	0.5	2.63486005089059	0.0150264879530695	0.275959420651641
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/3537	12/18639	0.5	2.63486005089059	0.0150264879530695	0.275959420651641
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/3537	12/18639	0.5	2.63486005089059	0.0150264879530695	0.275959420651641
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/3537	12/18639	0.5	2.63486005089059	0.0150264879530695	0.275959420651641
GO:0043022	ribosome binding	31/3537	112/18639	0.276785714285714	1.45858324245729	0.0156047259963474	0.282757635053814
GO:0005160	transforming growth factor beta receptor binding	10/3537	26/18639	0.384615384615385	2.02681542376199	0.0162686492680343	0.283449927631521
GO:0034237	protein kinase A regulatory subunit binding	10/3537	26/18639	0.384615384615385	2.02681542376199	0.0162686492680343	0.283449927631521
GO:0070412	R-SMAD binding	10/3537	26/18639	0.384615384615385	2.02681542376199	0.0162686492680343	0.283449927631521
GO:0050145	nucleoside monophosphate kinase activity	8/3537	19/18639	0.421052631578947	2.21882951653944	0.0171310054282339	0.294696662999619
GO:0031624	ubiquitin conjugating enzyme binding	11/3537	30/18639	0.366666666666667	1.93223070398643	0.0176125063572167	0.299192451743218
GO:0015179	L-amino acid transmembrane transporter activity	19/3537	62/18639	0.306451612903226	1.61491422473939	0.0183988259074471	0.302174666640501
GO:0004713	protein tyrosine kinase activity	37/3537	140/18639	0.264285714285714	1.39271174118502	0.0186551200251077	0.302174666640501
GO:0005109	frizzled binding	13/3537	38/18639	0.342105263157895	1.8027989821883	0.0190799906847131	0.302174666640501
GO:0019902	phosphatase binding	48/3537	190/18639	0.252631578947368	1.33129770992366	0.0191618772646152	0.302174666640501
GO:0005006	epidermal growth factor receptor activity	16/3537	50/18639	0.32	1.68631043256997	0.019344515082946	0.302174666640501
GO:0005017	platelet-derived growth factor receptor activity	16/3537	50/18639	0.32	1.68631043256997	0.019344515082946	0.302174666640501
GO:0005019	platelet-derived growth factor beta-receptor activity	16/3537	50/18639	0.32	1.68631043256997	0.019344515082946	0.302174666640501
GO:0141003	histone H2AX kinase activity	83/3537	354/18639	0.234463276836158	1.23555584307299	0.0199013693900808	0.307340465921816
GO:0016829	lyase activity	50/3537	200/18639	0.25	1.31743002544529	0.0206689277570039	0.314099440141027
GO:0042054	histone methyltransferase activity	20/3537	67/18639	0.298507462686567	1.5730507766511	0.0211369297023169	0.314099440141027
GO:0035091	phosphatidylinositol binding	68/3537	284/18639	0.23943661971831	1.26176396803211	0.0211541905947859	0.314099440141027
GO:0140030	modification-dependent protein binding	44/3537	173/18639	0.254335260115607	1.34027563282296	0.0215535977992362	0.314099440141027
GO:0005010	insulin-like growth factor receptor activity	16/3537	51/18639	0.313725490196078	1.65324552212743	0.023353293062545	0.314099440141027
GO:0005030	neurotrophin receptor activity	16/3537	51/18639	0.313725490196078	1.65324552212743	0.023353293062545	0.314099440141027
GO:0005035	death receptor activity	6/3537	13/18639	0.461538461538462	2.43217850851439	0.023492014672922	0.314099440141027
GO:0046975	histone H3K36 methyltransferase activity	6/3537	13/18639	0.461538461538462	2.43217850851439	0.023492014672922	0.314099440141027
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	6/3537	13/18639	0.461538461538462	2.43217850851439	0.023492014672922	0.314099440141027
GO:0140938	histone H3 methyltransferase activity	15/3537	47/18639	0.319148936170213	1.68182556439825	0.0236733682973612	0.314099440141027
GO:0016776	phosphotransferase activity, phosphate group as acceptor	13/3537	39/18639	0.333333333333333	1.75657336726039	0.0237743035590038	0.314099440141027
GO:0052745	inositol phosphate phosphatase activity	8/3537	20/18639	0.4	2.10788804071247	0.0238989799048571	0.314099440141027
GO:0032182	ubiquitin-like protein binding	32/3537	120/18639	0.266666666666667	1.40525869380831	0.0240707579966357	0.314099440141027
GO:0140996	histone H3 kinase activity	83/3537	357/18639	0.23249299719888	1.22517302086229	0.024197192286249	0.314099440141027
GO:0035591	signaling adaptor activity	34/3537	129/18639	0.263565891472868	1.38891847643845	0.0242835999953975	0.314099440141027
GO:0001618	virus receptor activity	23/3537	81/18639	0.283950617283951	1.49634027581441	0.0254540257618495	0.314099440141027
GO:0035035	histone acetyltransferase binding	9/3537	24/18639	0.375	1.97614503816794	0.0263784678935699	0.314099440141027
GO:0004955	prostaglandin receptor activity	5/3537	10/18639	0.5	2.63486005089059	0.0264621486843075	0.314099440141027
GO:0005031	tumor necrosis factor receptor activity	5/3537	10/18639	0.5	2.63486005089059	0.0264621486843075	0.314099440141027
GO:0016303	1-phosphatidylinositol-3-kinase activity	5/3537	10/18639	0.5	2.63486005089059	0.0264621486843075	0.314099440141027
GO:0016427	tRNA (cytidine) methyltransferase activity	5/3537	10/18639	0.5	2.63486005089059	0.0264621486843075	0.314099440141027
GO:0140999	histone H3K4 trimethyltransferase activity	5/3537	10/18639	0.5	2.63486005089059	0.0264621486843075	0.314099440141027
GO:0019209	kinase activator activity	38/3537	148/18639	0.256756756756757	1.35303624234922	0.0268990021552576	0.314099440141027
GO:0036408	histone H3K14 acetyltransferase activity	10/3537	28/18639	0.357142857142857	1.88204289349328	0.0279521622489519	0.314099440141027
GO:0005496	steroid binding	29/3537	108/18639	0.268518518518519	1.41501743473754	0.0280406434771792	0.314099440141027
GO:0016279	protein-lysine N-methyltransferase activity	20/3537	69/18639	0.289855072463768	1.52745510196556	0.0288142209354544	0.314099440141027
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	7/3537	17/18639	0.411764705882353	2.16988474779225	0.0288587717308708	0.314099440141027
GO:0008484	sulfuric ester hydrolase activity	7/3537	17/18639	0.411764705882353	2.16988474779225	0.0288587717308708	0.314099440141027
GO:0019198	transmembrane receptor protein phosphatase activity	7/3537	17/18639	0.411764705882353	2.16988474779225	0.0288587717308708	0.314099440141027
GO:0070403	NAD+ binding	7/3537	17/18639	0.411764705882353	2.16988474779225	0.0288587717308708	0.314099440141027
GO:0140272	exogenous protein binding	23/3537	82/18639	0.280487804878049	1.47809222367033	0.0292081041027294	0.314099440141027
GO:0035173	histone kinase activity	83/3537	360/18639	0.230555555555556	1.21496324568844	0.0292113300167425	0.314099440141027
GO:0016409	palmitoyltransferase activity	12/3537	36/18639	0.333333333333333	1.75657336726039	0.029246706400539	0.314099440141027
GO:0044390	ubiquitin-like protein conjugating enzyme binding	12/3537	36/18639	0.333333333333333	1.75657336726039	0.029246706400539	0.314099440141027
GO:0038024	cargo receptor activity	19/3537	65/18639	0.292307692307692	1.54037972205911	0.0299484276219027	0.314099440141027
GO:0033218	amide binding	59/3537	247/18639	0.238866396761134	1.25875905265218	0.0313150787296986	0.314099440141027
GO:0015174	basic amino acid transmembrane transporter activity	8/3537	21/18639	0.380952380952381	2.00751241972616	0.0323377322837126	0.314099440141027
GO:0005003	ephrin receptor activity	16/3537	53/18639	0.30188679245283	1.59085889865092	0.0332006579848684	0.314099440141027
GO:0005005	transmembrane-ephrin receptor activity	16/3537	53/18639	0.30188679245283	1.59085889865092	0.0332006579848684	0.314099440141027
GO:0051018	protein kinase A binding	16/3537	53/18639	0.30188679245283	1.59085889865092	0.0332006579848684	0.314099440141027
GO:1901505	carbohydrate derivative transmembrane transporter activity	16/3537	53/18639	0.30188679245283	1.59085889865092	0.0332006579848684	0.314099440141027
GO:0016278	lysine N-methyltransferase activity	20/3537	70/18639	0.285714285714286	1.50563431479462	0.0333607606834045	0.314099440141027
GO:0001540	amyloid-beta binding	23/3537	83/18639	0.27710843373494	1.46028388362611	0.0333671395426466	0.314099440141027
GO:0005004	GPI-linked ephrin receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0005008	hepatocyte growth factor receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0005009	insulin receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0005011	macrophage colony-stimulating factor receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0005018	platelet-derived growth factor alpha-receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0005020	stem cell factor receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0008288	boss receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0016763	pentosyltransferase activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0036332	placental growth factor receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0038062	protein tyrosine kinase collagen receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0060175	brain-derived neurotrophic factor receptor activity	15/3537	49/18639	0.306122448979592	1.61317962299424	0.0341552537836662	0.314099440141027
GO:0043178	alcohol binding	25/3537	92/18639	0.271739130434783	1.43198915809271	0.0343328395210337	0.314099440141027
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	9/3537	25/18639	0.36	1.89709923664122	0.0344579696446168	0.314099440141027
GO:0005161	platelet-derived growth factor receptor binding	6/3537	14/18639	0.428571428571429	2.25845147219193	0.0346406284109109	0.314099440141027
GO:0008191	metalloendopeptidase inhibitor activity	6/3537	14/18639	0.428571428571429	2.25845147219193	0.0346406284109109	0.314099440141027
GO:0032036	myosin heavy chain binding	6/3537	14/18639	0.428571428571429	2.25845147219193	0.0346406284109109	0.314099440141027
GO:0046030	inositol trisphosphate phosphatase activity	6/3537	14/18639	0.428571428571429	2.25845147219193	0.0346406284109109	0.314099440141027
GO:0008009	chemokine activity	14/3537	45/18639	0.311111111111111	1.6394684761097	0.0349847532780459	0.314099440141027
GO:0046915	transition metal ion transmembrane transporter activity	14/3537	45/18639	0.311111111111111	1.6394684761097	0.0349847532780459	0.314099440141027
GO:0046332	SMAD binding	22/3537	79/18639	0.278481012658228	1.46751699036944	0.0349932100666514	0.314099440141027
GO:0010484	histone H3 acetyltransferase activity	10/3537	29/18639	0.344827586206897	1.81714486268316	0.0356089722918553	0.314099440141027
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	13/3537	41/18639	0.317073170731707	1.67088686154037	0.0356340837647779	0.314099440141027
GO:0015291	secondary active transmembrane transporter activity	67/3537	287/18639	0.233449477351916	1.2302134035517	0.0363540092795428	0.314099440141027
GO:0005516	calmodulin binding	50/3537	207/18639	0.241545893719807	1.27287925163796	0.0371274094762615	0.314099440141027
GO:0035401	histone H3Y41 kinase activity	30/3537	115/18639	0.260869565217391	1.374709591769	0.0372555602104387	0.314099440141027
GO:0140801	histone H2AXY142 kinase activity	30/3537	115/18639	0.260869565217391	1.374709591769	0.0372555602104387	0.314099440141027
GO:0022804	active transmembrane transporter activity	102/3537	457/18639	0.223194748358862	1.17617385203869	0.039093295526036	0.314099440141027
GO:0016854	racemase and epimerase activity	7/3537	18/18639	0.388888888888889	2.04933559513712	0.0396781385288254	0.314099440141027
GO:0030228	lipoprotein particle receptor activity	7/3537	18/18639	0.388888888888889	2.04933559513712	0.0396781385288254	0.314099440141027
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	19/3537	67/18639	0.283582089552239	1.49439823781854	0.0402101547647037	0.314099440141027
GO:0005007	fibroblast growth factor receptor activity	15/3537	50/18639	0.3	1.58091603053435	0.0405027132268319	0.314099440141027
GO:0015605	organophosphate ester transmembrane transporter activity	15/3537	50/18639	0.3	1.58091603053435	0.0405027132268319	0.314099440141027
GO:0004954	prostanoid receptor activity	5/3537	11/18639	0.454545454545455	2.39532731899144	0.041069607136602	0.314099440141027
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/3537	11/18639	0.454545454545455	2.39532731899144	0.041069607136602	0.314099440141027
GO:0032794	GTPase activating protein binding	5/3537	11/18639	0.454545454545455	2.39532731899144	0.041069607136602	0.314099440141027
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/3537	11/18639	0.454545454545455	2.39532731899144	0.041069607136602	0.314099440141027
GO:0140031	phosphorylation-dependent protein binding	5/3537	11/18639	0.454545454545455	2.39532731899144	0.041069607136602	0.314099440141027
GO:1901981	phosphatidylinositol phosphate binding	45/3537	185/18639	0.243243243243243	1.28182380854137	0.0413920184815586	0.314099440141027
GO:0003714	transcription corepressor activity	49/3537	204/18639	0.240196078431373	1.26576610287881	0.0423332203731404	0.314099440141027
GO:0008168	methyltransferase activity	49/3537	204/18639	0.240196078431373	1.26576610287881	0.0423332203731404	0.314099440141027
GO:0032931	histone H3K56 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0043992	histone H3K9 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0043993	histone H3K18 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0043994	histone H3K23 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0043999	histone H2AK5 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0044012	histone H2AK9 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0044014	histone H2BK5 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0044015	histone H2BK12 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0044016	histone H3K4 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0044017	histone H3K27 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0044018	histone H3K36 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0070034	telomerase RNA binding	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0140908	histone H3K122 acetyltransferase activity	8/3537	22/18639	0.363636363636364	1.91626185519315	0.0425965410691261	0.314099440141027
GO:0004540	RNA nuclease activity	31/3537	121/18639	0.256198347107438	1.35009357979518	0.0434481873529188	0.314099440141027
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	41/3537	167/18639	0.245508982035928	1.29376361780256	0.0435633529376352	0.314099440141027
GO:0042393	histone binding	58/3537	247/18639	0.234817813765182	1.23742415345469	0.043920615245043	0.314099440141027
GO:0005518	collagen binding	20/3537	72/18639	0.277777777777778	1.46381113938366	0.0440176522784605	0.314099440141027
GO:0004435	phosphatidylinositol phospholipase C activity	9/3537	26/18639	0.346153846153846	1.82413388138579	0.0440876098439841	0.314099440141027
GO:0043995	histone H4K5 acetyltransferase activity	10/3537	30/18639	0.333333333333333	1.75657336726039	0.0446072052591746	0.314099440141027
GO:0043996	histone H4K8 acetyltransferase activity	10/3537	30/18639	0.333333333333333	1.75657336726039	0.0446072052591746	0.314099440141027
GO:0043997	histone H4K12 acetyltransferase activity	10/3537	30/18639	0.333333333333333	1.75657336726039	0.0446072052591746	0.314099440141027
GO:0070566	adenylyltransferase activity	10/3537	30/18639	0.333333333333333	1.75657336726039	0.0446072052591746	0.314099440141027
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	54/3537	229/18639	0.235807860262009	1.24264142138071	0.0470129709480009	0.3293331315378
GO:0005021	vascular endothelial growth factor receptor activity	15/3537	51/18639	0.294117647058824	1.54991767699446	0.0476483049619516	0.332072033042524
GO:0004953	icosanoid receptor activity	6/3537	15/18639	0.4	2.10788804071247	0.0486950979748593	0.332545920340874
GO:0005041	low-density lipoprotein particle receptor activity	6/3537	15/18639	0.4	2.10788804071247	0.0486950979748593	0.332545920340874
GO:0141050	histone H3K deacetylase activity	6/3537	15/18639	0.4	2.10788804071247	0.0486950979748593	0.332545920340874
GO:0141051	histone H4K deacetylase activity	6/3537	15/18639	0.4	2.10788804071247	0.0486950979748593	0.332545920340874
GO:0004521	RNA endonuclease activity	20/3537	73/18639	0.273972602739726	1.44375893199484	0.0501824832327593	0.3409899735666
GO:0002039	p53 binding	19/3537	69/18639	0.27536231884058	1.45108234686728	0.0528134372854928	0.353678965646146
GO:0042800	histone H3K4 methyltransferase activity	7/3537	19/18639	0.368421052631579	1.94147582697201	0.0528306328375038	0.353678965646146
GO:0140036	ubiquitin-modified protein reader activity	7/3537	19/18639	0.368421052631579	1.94147582697201	0.0528306328375038	0.353678965646146
GO:0008514	organic anion transmembrane transporter activity	62/3537	269/18639	0.230483271375465	1.21458232829157	0.0532903989675222	0.355008099004229
GO:0005154	epidermal growth factor receptor binding	11/3537	35/18639	0.314285714285714	1.65619774627408	0.0540952745136849	0.358308478003657
GO:0004602	glutathione peroxidase activity	8/3537	23/18639	0.347826086956522	1.83294612235867	0.0547906573893174	0.358308478003657
GO:0044013	histone H2B acetyltransferase activity	8/3537	23/18639	0.347826086956522	1.83294612235867	0.0547906573893174	0.358308478003657
GO:0070325	lipoprotein particle receptor binding	10/3537	31/18639	0.32258064516129	1.69990971025199	0.0550254629081701	0.358308478003657
GO:0005385	zinc ion transmembrane transporter activity	9/3537	27/18639	0.333333333333333	1.75657336726039	0.0553606185015944	0.358308478003657
GO:0008237	metallopeptidase activity	44/3537	184/18639	0.239130434782609	1.26015045912158	0.0554018281204747	0.358308478003657
GO:0030159	signaling receptor complex adaptor activity	15/3537	52/18639	0.288461538461538	1.52011156782149	0.055631411963776	0.358308478003657
GO:0004300	enoyl-CoA hydratase activity	5/3537	12/18639	0.416666666666667	2.19571670907549	0.0596718351248396	0.371990935480078
GO:0016208	AMP binding	5/3537	12/18639	0.416666666666667	2.19571670907549	0.0596718351248396	0.371990935480078
GO:0017166	vinculin binding	5/3537	12/18639	0.416666666666667	2.19571670907549	0.0596718351248396	0.371990935480078
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/3537	12/18639	0.416666666666667	2.19571670907549	0.0596718351248396	0.371990935480078
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	5/3537	12/18639	0.416666666666667	2.19571670907549	0.0596718351248396	0.371990935480078
GO:1990459	transferrin receptor binding	5/3537	12/18639	0.416666666666667	2.19571670907549	0.0596718351248396	0.371990935480078
GO:1990817	poly(A) RNA polymerase activity	5/3537	12/18639	0.416666666666667	2.19571670907549	0.0596718351248396	0.371990935480078
GO:0001223	transcription coactivator binding	13/3537	44/18639	0.295454545454545	1.55696275734444	0.0605036583716886	0.375454208799656
GO:0015932	nucleobase-containing compound transmembrane transporter activity	16/3537	57/18639	0.280701754385965	1.47921967769296	0.0614067459252751	0.379326216874768
GO:0038064	collagen receptor activity	15/3537	53/18639	0.283018867924528	1.49143021748524	0.0644856569554501	0.392902961539968
GO:0051117	ATPase binding	22/3537	84/18639	0.261904761904762	1.38016478856174	0.0645495581955954	0.392902961539968
GO:0005484	SNAP receptor activity	11/3537	36/18639	0.305555555555556	1.61019225332202	0.065028644483469	0.392902961539968
GO:0005324	long-chain fatty acid transmembrane transporter activity	6/3537	16/18639	0.375	1.97614503816794	0.0657798361456611	0.392902961539968
GO:0034450	ubiquitin-ubiquitin ligase activity	6/3537	16/18639	0.375	1.97614503816794	0.0657798361456611	0.392902961539968
GO:0043023	ribosomal large subunit binding	6/3537	16/18639	0.375	1.97614503816794	0.0657798361456611	0.392902961539968
GO:0070411	I-SMAD binding	6/3537	16/18639	0.375	1.97614503816794	0.0657798361456611	0.392902961539968
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	32/3537	130/18639	0.246153846153846	1.29716187120767	0.065917494651297	0.392902961539968
GO:0016741	transferase activity, transferring one-carbon groups	50/3537	215/18639	0.232558139534884	1.22551630273981	0.0665984862808051	0.393673545634914
GO:0043021	ribonucleoprotein complex binding	42/3537	177/18639	0.23728813559322	1.25044205804977	0.0666261335511627	0.393673545634914
GO:0042626	ATPase-coupled transmembrane transporter activity	25/3537	98/18639	0.255102040816327	1.3443163524952	0.0673720697814763	0.396357761181932
GO:0019789	SUMO transferase activity	9/3537	28/18639	0.321428571428571	1.69383860414395	0.0683435714633724	0.397316043027299
GO:0016004	phospholipase activator activity	7/3537	20/18639	0.35	1.84440203562341	0.0684092151858519	0.397316043027299
GO:0043998	histone H2A acetyltransferase activity	8/3537	24/18639	0.333333333333333	1.75657336726039	0.068996752137191	0.397316043027299
GO:0060229	lipase activator activity	8/3537	24/18639	0.333333333333333	1.75657336726039	0.068996752137191	0.397316043027299
GO:0140033	acetylation-dependent protein binding	8/3537	24/18639	0.333333333333333	1.75657336726039	0.068996752137191	0.397316043027299
GO:0004722	protein serine/threonine phosphatase activity	26/3537	103/18639	0.252427184466019	1.33022060821661	0.0703113204186062	0.403177571514286
GO:0005319	lipid transporter activity	42/3537	178/18639	0.235955056179775	1.24341710266747	0.0717555107540143	0.40820074155221
GO:0008194	UDP-glycosyltransferase activity	35/3537	145/18639	0.241379310344828	1.27200140387821	0.0717880627159517	0.40820074155221
GO:0042169	SH2 domain binding	12/3537	41/18639	0.292682926829268	1.54235710296034	0.0741084074177692	0.417734094023739
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	15/3537	54/18639	0.277777777777778	1.46381113938366	0.0742381841780256	0.417734094023739
GO:0046943	carboxylic acid transmembrane transporter activity	44/3537	188/18639	0.234042553191489	1.23333874722538	0.074386792313278	0.417734094023739
GO:0019213	deacetylase activity	11/3537	37/18639	0.297297297297297	1.56667354377278	0.0772978134041966	0.432295178667914
GO:0005342	organic acid transmembrane transporter activity	44/3537	189/18639	0.232804232804233	1.22681314538821	0.0797749773941831	0.441858410661954
GO:0043177	organic acid binding	44/3537	189/18639	0.232804232804233	1.22681314538821	0.0797749773941831	0.441858410661954
GO:0050660	flavin adenine dinucleotide binding	22/3537	86/18639	0.255813953488372	1.34806793301379	0.0801812254077918	0.441858410661954
GO:0031593	polyubiquitin modification-dependent protein binding	16/3537	59/18639	0.271186440677966	1.42907663777116	0.0803083351239902	0.441858410661954
GO:0005542	folic acid binding	5/3537	13/18639	0.384615384615385	2.02681542376199	0.0822842229072882	0.449093409361465
GO:0039706	co-receptor binding	5/3537	13/18639	0.384615384615385	2.02681542376199	0.0822842229072882	0.449093409361465
GO:0004629	phospholipase C activity	9/3537	29/18639	0.310344827586207	1.63543037641485	0.0830741410905552	0.449791863514201
GO:0016417	S-acyltransferase activity	9/3537	29/18639	0.310344827586207	1.63543037641485	0.0830741410905552	0.449791863514201
GO:0051015	actin filament binding	48/3537	209/18639	0.229665071770335	1.21027064538515	0.0844047603809517	0.455182814911561
GO:0019706	protein-cysteine S-palmitoyltransferase activity	8/3537	25/18639	0.32	1.68631043256997	0.085250296839579	0.45612265120074
GO:0019707	protein-cysteine S-acyltransferase activity	8/3537	25/18639	0.32	1.68631043256997	0.085250296839579	0.45612265120074
GO:0004550	nucleoside diphosphate kinase activity	6/3537	17/18639	0.352941176470588	1.85990121239335	0.0859185985537284	0.457895589939282
GO:0051010	microtubule plus-end binding	7/3537	21/18639	0.333333333333333	1.75657336726039	0.0864449566369216	0.458901156521783
GO:0019787	ubiquitin-like protein transferase activity	103/3537	479/18639	0.215031315240084	1.13315484443311	0.0868377482613279	0.459192606564765
GO:0004222	metalloendopeptidase activity	27/3537	110/18639	0.245454545454545	1.29347675225538	0.0879167082066695	0.463096149042108
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	16/3537	60/18639	0.266666666666667	1.40525869380831	0.0910369714911052	0.465224594107503
GO:0000287	magnesium ion binding	52/3537	230/18639	0.226086956521739	1.19141497953313	0.0938329689941229	0.465224594107503
GO:0030165	PDZ domain binding	21/3537	83/18639	0.253012048192771	1.33330267635427	0.0943445617812791	0.465224594107503
GO:0008175	tRNA methyltransferase activity	10/3537	34/18639	0.294117647058824	1.54991767699446	0.095288602497375	0.465224594107503
GO:0035064	methylated histone binding	19/3537	74/18639	0.256756756756757	1.35303624234922	0.09581459707798	0.465224594107503
GO:0004676	3-phosphoinositide-dependent protein kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0004711	ribosomal protein S6 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0035175	histone H3S10 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0035979	histone H2AXS139 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0044022	histone H3S28 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0044023	histone H4S1 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0044024	histone H2AS1 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0044025	histone H2BS14 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0072354	histone H3T3 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0072371	histone H2AS121 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0072518	Rho-dependent protein serine/threonine kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0140823	histone H2BS36 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0140855	histone H3S57 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0140995	histone H2A kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0140997	histone H4 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0140998	histone H2B kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:1990244	histone H2AT120 kinase activity	55/3537	245/18639	0.224489795918367	1.18299839019577	0.0963146301938446	0.465224594107503
GO:0031406	carboxylic acid binding	43/3537	187/18639	0.229946524064171	1.21175382019567	0.0963325038438754	0.465224594107503
GO:0016887	ATP hydrolysis activity	90/3537	417/18639	0.215827338129496	1.13734966225493	0.0965366707419543	0.465224594107503
GO:0015171	amino acid transmembrane transporter activity	25/3537	102/18639	0.245098039215686	1.29159806416205	0.0989262952119566	0.475055954745756
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	12/3537	43/18639	0.27906976744186	1.47061956328777	0.100276788757322	0.479845619440846
GO:0045296	cadherin binding	73/3537	334/18639	0.218562874251497	1.15176517194618	0.100994634714924	0.481584942377481
GO:0004677	DNA-dependent protein kinase activity	55/3537	246/18639	0.223577235772358	1.17818945365026	0.101959284135565	0.482796749617536
GO:0140857	histone H3T45 kinase activity	55/3537	246/18639	0.223577235772358	1.17818945365026	0.101959284135565	0.482796749617536
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/3537	10/18639	0.4	2.10788804071247	0.103485172603865	0.485232470173542
GO:0005528	FK506 binding	4/3537	10/18639	0.4	2.10788804071247	0.103485172603865	0.485232470173542
GO:0030247	polysaccharide binding	8/3537	26/18639	0.307692307692308	1.62145233900959	0.103544824393177	0.485232470173542
GO:0019842	vitamin binding	35/3537	150/18639	0.233333333333333	1.22960135708227	0.105430848789494	0.489055340004749
GO:0008093	cytoskeletal anchor activity	7/3537	22/18639	0.318181818181818	1.67672912329401	0.106907550568559	0.489055340004749
GO:0046972	histone H4K16 acetyltransferase activity	7/3537	22/18639	0.318181818181818	1.67672912329401	0.106907550568559	0.489055340004749
GO:0019838	growth factor binding	32/3537	136/18639	0.235294117647059	1.23993414159557	0.107697031718982	0.489055340004749
GO:0035402	histone H3T11 kinase activity	55/3537	247/18639	0.222672064777328	1.1734194558622	0.10782235845719	0.489055340004749
GO:0035403	histone H3T6 kinase activity	55/3537	247/18639	0.222672064777328	1.1734194558622	0.10782235845719	0.489055340004749
GO:0008195	phosphatidate phosphatase activity	5/3537	14/18639	0.357142857142857	1.88204289349328	0.108752886516387	0.489055340004749
GO:0008559	ABC-type xenobiotic transporter activity	5/3537	14/18639	0.357142857142857	1.88204289349328	0.108752886516387	0.489055340004749
GO:0042043	neurexin family protein binding	5/3537	14/18639	0.357142857142857	1.88204289349328	0.108752886516387	0.489055340004749
GO:0061665	SUMO ligase activity	5/3537	14/18639	0.357142857142857	1.88204289349328	0.108752886516387	0.489055340004749
GO:0000900	mRNA regulatory element binding translation repressor activity	6/3537	18/18639	0.333333333333333	1.75657336726039	0.10903882856618	0.489055340004749
GO:0017075	syntaxin-1 binding	6/3537	18/18639	0.333333333333333	1.75657336726039	0.10903882856618	0.489055340004749
GO:1990381	ubiquitin-specific protease binding	6/3537	18/18639	0.333333333333333	1.75657336726039	0.10903882856618	0.489055340004749
GO:0010485	histone H4 acetyltransferase activity	10/3537	35/18639	0.285714285714286	1.50563431479462	0.111765933690851	0.497999684871693
GO:0043015	gamma-tubulin binding	10/3537	35/18639	0.285714285714286	1.50563431479462	0.111765933690851	0.497999684871693
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	54/3537	243/18639	0.222222222222222	1.17104891150693	0.113209691677027	0.501420811906458
GO:0140299	molecular sensor activity	18/3537	71/18639	0.253521126760563	1.33598537791635	0.113271662439502	0.501420811906458
GO:0004679	AMP-activated protein kinase activity	55/3537	248/18639	0.221774193548387	1.16868792579824	0.113905301204164	0.502588650443048
GO:0016755	aminoacyltransferase activity	105/3537	496/18639	0.211693548387097	1.11556574735287	0.11510568723462	0.504985604819286
GO:0019205	nucleobase-containing compound kinase activity	12/3537	44/18639	0.272727272727273	1.43719639139486	0.115191712651934	0.504985604819286
GO:0005178	integrin binding	37/3537	161/18639	0.229813664596273	1.21105368798698	0.116409840563478	0.508684801690569
GO:0017022	myosin binding	19/3537	76/18639	0.25	1.31743002544529	0.117906575930282	0.511933024566306
GO:0140034	methylation-dependent protein binding	19/3537	76/18639	0.25	1.31743002544529	0.117906575930282	0.511933024566306
GO:0016500	protein-hormone receptor activity	17/3537	67/18639	0.253731343283582	1.33709316015343	0.120556191640812	0.520113855364648
GO:0050840	extracellular matrix binding	17/3537	67/18639	0.253731343283582	1.33709316015343	0.120556191640812	0.520113855364648
GO:0008276	protein methyltransferase activity	23/3537	95/18639	0.242105263157895	1.27582697201018	0.121933690054846	0.524392040457391
GO:0035254	glutamate receptor binding	13/3537	49/18639	0.26530612244898	1.398089006595	0.123339982841026	0.528766677226986
GO:0035255	ionotropic glutamate receptor binding	8/3537	27/18639	0.296296296296296	1.5613985486759	0.123832911084369	0.529210459634145
GO:0004842	ubiquitin-protein transferase activity	95/3537	449/18639	0.211581291759465	1.11497418634568	0.129324249306535	0.543591394379346
GO:0003887	DNA-directed DNA polymerase activity	7/3537	23/18639	0.304347826086957	1.60382785706383	0.129708691334478	0.543591394379346
GO:0005158	insulin receptor binding	7/3537	23/18639	0.304347826086957	1.60382785706383	0.129708691334478	0.543591394379346
GO:0031681	G-protein beta-subunit binding	7/3537	23/18639	0.304347826086957	1.60382785706383	0.129708691334478	0.543591394379346
GO:0070577	lysine-acetylated histone binding	7/3537	23/18639	0.304347826086957	1.60382785706383	0.129708691334478	0.543591394379346
GO:0051287	NAD binding	14/3537	54/18639	0.259259259259259	1.36622373009141	0.130530585170768	0.543591394379346
GO:0140303	intramembrane lipid transporter activity	12/3537	45/18639	0.266666666666667	1.40525869380831	0.131308439592281	0.543591394379346
GO:0004896	cytokine receptor activity	23/3537	96/18639	0.239583333333333	1.26253710771841	0.132902783421049	0.543591394379346
GO:0003777	microtubule motor activity	17/3537	68/18639	0.25	1.31743002544529	0.133714845960777	0.543591394379346
GO:0015245	fatty acid transmembrane transporter activity	6/3537	19/18639	0.315789473684211	1.66412213740458	0.134981072748646	0.543591394379346
GO:0046527	glucosyltransferase activity	6/3537	19/18639	0.315789473684211	1.66412213740458	0.134981072748646	0.543591394379346
GO:0045309	protein phosphorylated amino acid binding	15/3537	59/18639	0.254237288135593	1.33975934791047	0.136906308917573	0.543591394379346
GO:0008378	galactosyltransferase activity	9/3537	32/18639	0.28125	1.48210877862595	0.137678583135063	0.543591394379346
GO:0015106	bicarbonate transmembrane transporter activity	9/3537	32/18639	0.28125	1.48210877862595	0.137678583135063	0.543591394379346
GO:0042910	xenobiotic transmembrane transporter activity	9/3537	32/18639	0.28125	1.48210877862595	0.137678583135063	0.543591394379346
GO:0070717	poly-purine tract binding	9/3537	32/18639	0.28125	1.48210877862595	0.137678583135063	0.543591394379346
GO:0120015	sterol transfer activity	9/3537	32/18639	0.28125	1.48210877862595	0.137678583135063	0.543591394379346
GO:0033130	acetylcholine receptor binding	5/3537	15/18639	0.333333333333333	1.75657336726039	0.13878178078715	0.543591394379346
GO:0048531	beta-1,3-galactosyltransferase activity	5/3537	15/18639	0.333333333333333	1.75657336726039	0.13878178078715	0.543591394379346
GO:0120283	protein serine/threonine kinase binding	5/3537	15/18639	0.333333333333333	1.75657336726039	0.13878178078715	0.543591394379346
GO:0008172	S-methyltransferase activity	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0008271	secondary active sulfate transmembrane transporter activity	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0032050	clathrin heavy chain binding	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0034713	type I transforming growth factor beta receptor binding	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0045294	alpha-catenin binding	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0050998	nitric-oxide synthase binding	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0180030	inositol phosphate kinase activity	4/3537	11/18639	0.363636363636364	1.91626185519315	0.139151210013729	0.543591394379346
GO:0048020	CCR chemokine receptor binding	13/3537	50/18639	0.26	1.3701272264631	0.13919779635321	0.543591394379346
GO:0017080	sodium channel regulator activity	11/3537	41/18639	0.268292682926829	1.41382734438031	0.139896663846758	0.544755203919038
GO:0015297	antiporter activity	31/3537	135/18639	0.22962962962963	1.21008387522382	0.141629846742417	0.549928462065558
GO:0051959	dynein light intermediate chain binding	8/3537	28/18639	0.285714285714286	1.50563431479462	0.146028646932768	0.565392966329434
GO:0008238	exopeptidase activity	24/3537	102/18639	0.235294117647059	1.23993414159557	0.147321248366205	0.568777206050207
GO:0023023	MHC protein complex binding	10/3537	37/18639	0.27027027027027	1.42424867615707	0.149165518137092	0.574266116567445
GO:0004674	protein serine/threonine kinase activity	91/3537	433/18639	0.210161662817552	1.10749313917341	0.150865399146669	0.579169710283398
GO:0003684	damaged DNA binding	18/3537	74/18639	0.243243243243243	1.28182380854137	0.152215723083845	0.582707514566041
GO:0015295	solute:proton symporter activity	7/3537	24/18639	0.291666666666667	1.53700169635284	0.154707725121596	0.584422380488405
GO:0042625	ATPase-coupled ion transmembrane transporter activity	7/3537	24/18639	0.291666666666667	1.53700169635284	0.154707725121596	0.584422380488405
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	7/3537	24/18639	0.291666666666667	1.53700169635284	0.154707725121596	0.584422380488405
GO:0046961	proton-transporting ATPase activity, rotational mechanism	7/3537	24/18639	0.291666666666667	1.53700169635284	0.154707725121596	0.584422380488405
GO:0015293	symporter activity	33/3537	146/18639	0.226027397260274	1.19110111889574	0.154813875626067	0.584422380488405
GO:0016597	amino acid binding	13/3537	51/18639	0.254901960784314	1.34326198672853	0.156107765786254	0.58466744363375
GO:0016830	carbon-carbon lyase activity	13/3537	51/18639	0.254901960784314	1.34326198672853	0.156107765786254	0.58466744363375
GO:0008170	N-methyltransferase activity	23/3537	98/18639	0.23469387755102	1.23677104429558	0.156525959416978	0.58466744363375
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	28/3537	122/18639	0.229508196721311	1.20944395778584	0.156741867122207	0.58466744363375
GO:0160215	deacylase activity	16/3537	65/18639	0.246153846153846	1.29716187120767	0.157584621518456	0.58466744363375
GO:0048487	beta-tubulin binding	11/3537	42/18639	0.261904761904762	1.38016478856174	0.158815046693813	0.58466744363375
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	9/3537	33/18639	0.272727272727273	1.43719639139486	0.15918098171044	0.58466744363375
GO:0019239	deaminase activity	9/3537	33/18639	0.272727272727273	1.43719639139486	0.15918098171044	0.58466744363375
GO:0030296	protein tyrosine kinase activator activity	9/3537	33/18639	0.272727272727273	1.43719639139486	0.15918098171044	0.58466744363375
GO:0071889	14-3-3 protein binding	9/3537	33/18639	0.272727272727273	1.43719639139486	0.15918098171044	0.58466744363375
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/3537	20/18639	0.3	1.58091603053435	0.163511868846987	0.592567012701479
GO:0015095	magnesium ion transmembrane transporter activity	6/3537	20/18639	0.3	1.58091603053435	0.163511868846987	0.592567012701479
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	6/3537	20/18639	0.3	1.58091603053435	0.163511868846987	0.592567012701479
GO:0031418	L-ascorbic acid binding	6/3537	20/18639	0.3	1.58091603053435	0.163511868846987	0.592567012701479
GO:0140939	histone H4 methyltransferase activity	6/3537	20/18639	0.3	1.58091603053435	0.163511868846987	0.592567012701479
GO:0043495	protein-membrane adaptor activity	12/3537	47/18639	0.25531914893617	1.3454604515186	0.167008257210922	0.601921191871372
GO:0043236	laminin binding	8/3537	29/18639	0.275862068965517	1.45371589014653	0.170011315825039	0.601921191871372
GO:0003713	transcription coactivator activity	55/3537	256/18639	0.21484375	1.13216642811705	0.170522567877782	0.601921191871372
GO:0005024	transforming growth factor beta receptor activity	5/3537	16/18639	0.3125	1.64678753180662	0.171964482896918	0.601921191871372
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/3537	16/18639	0.3125	1.64678753180662	0.171964482896918	0.601921191871372
GO:0022858	alanine transmembrane transporter activity	5/3537	16/18639	0.3125	1.64678753180662	0.171964482896918	0.601921191871372
GO:0008235	metalloexopeptidase activity	16/3537	66/18639	0.242424242424242	1.2775079034621	0.173388489663125	0.601921191871372
GO:0140098	catalytic activity, acting on RNA	81/3537	387/18639	0.209302325581395	1.10296467246583	0.17692901931735	0.601921191871372
GO:0061659	ubiquitin-like protein ligase activity	78/3537	372/18639	0.209677419354839	1.10494131166379	0.177533443963946	0.601921191871372
GO:0004000	adenosine deaminase activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0005025	transforming growth factor beta receptor activity, type I	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0005026	transforming growth factor beta receptor activity, type II	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0005527	macrolide binding	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0008179	adenylate cyclase binding	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0008603	cAMP-dependent protein kinase regulator activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0016361	activin receptor activity, type I	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0016362	activin receptor activity, type II	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0016840	carbon-nitrogen lyase activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0017002	activin receptor activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0031543	peptidyl-proline dioxygenase activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0034452	dynactin binding	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0035251	UDP-glucosyltransferase activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0035497	cAMP response element binding	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0070008	serine-type exopeptidase activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0140829	bicarbonate:monoatomic anion antiporter activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0140900	chloride:bicarbonate antiporter activity	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/3537	12/18639	0.333333333333333	1.75657336726039	0.178890897458174	0.601921191871372
GO:0004712	protein serine/threonine/tyrosine kinase activity	11/3537	43/18639	0.255813953488372	1.34806793301379	0.178937572859481	0.601921191871372
GO:0048156	tau protein binding	11/3537	43/18639	0.255813953488372	1.34806793301379	0.178937572859481	0.601921191871372
GO:0003707	nuclear steroid receptor activity	7/3537	25/18639	0.28	1.47552162849873	0.18171894723127	0.603867467684603
GO:0008139	nuclear localization sequence binding	7/3537	25/18639	0.28	1.47552162849873	0.18171894723127	0.603867467684603
GO:0120020	cholesterol transfer activity	7/3537	25/18639	0.28	1.47552162849873	0.18171894723127	0.603867467684603
GO:0008376	acetylgalactosaminyltransferase activity	9/3537	34/18639	0.264705882352941	1.39492590929502	0.182182238227143	0.603867467684603
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	9/3537	34/18639	0.264705882352941	1.39492590929502	0.182182238227143	0.603867467684603
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	9/3537	34/18639	0.264705882352941	1.39492590929502	0.182182238227143	0.603867467684603
GO:0019903	protein phosphatase binding	32/3537	144/18639	0.222222222222222	1.17104891150693	0.185291616982332	0.61267958024085
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	10/3537	39/18639	0.256410256410256	1.35121028250799	0.192053739308094	0.633497649805095
GO:0017046	peptide hormone binding	13/3537	53/18639	0.245283018867925	1.29257285515387	0.192908491235728	0.634776367044441
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/3537	21/18639	0.285714285714286	1.50563431479462	0.194338633731012	0.636400489736014
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/3537	21/18639	0.285714285714286	1.50563431479462	0.194338633731012	0.636400489736014
GO:0001968	fibronectin binding	8/3537	30/18639	0.266666666666667	1.40525869380831	0.195629986767754	0.63908930773408
GO:1902936	phosphatidylinositol bisphosphate binding	25/3537	111/18639	0.225225225225225	1.18687389679756	0.199867253385859	0.65084458418673
GO:0030020	extracellular matrix structural constituent conferring tensile strength	11/3537	44/18639	0.25	1.31743002544529	0.200186192928663	0.65084458418673
GO:1901682	sulfur compound transmembrane transporter activity	15/3537	63/18639	0.238095238095238	1.25469526232885	0.203154295560371	0.658329170783784
GO:0140566	histone reader activity	9/3537	35/18639	0.257142857142857	1.35507088331516	0.206557112874321	0.658329170783784
GO:0106310	protein serine kinase activity	75/3537	361/18639	0.207756232686981	1.09481719566091	0.206886962349186	0.658329170783784
GO:0004549	tRNA-specific ribonuclease activity	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0004659	prenyltransferase activity	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0005092	GDP-dissociation inhibitor activity	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0008569	minus-end-directed microtubule motor activity	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0017110	nucleoside diphosphate phosphatase activity	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0046965	nuclear retinoid X receptor binding	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0048038	quinone binding	5/3537	17/18639	0.294117647058824	1.54991767699446	0.207816934706581	0.658329170783784
GO:0008143	poly(A) binding	7/3537	26/18639	0.269230769230769	1.41877079663339	0.21051993985583	0.6622606441298
GO:0050750	low-density lipoprotein particle receptor binding	7/3537	26/18639	0.269230769230769	1.41877079663339	0.21051993985583	0.6622606441298
GO:0070006	metalloaminopeptidase activity	7/3537	26/18639	0.269230769230769	1.41877079663339	0.21051993985583	0.6622606441298
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	19/3537	83/18639	0.228915662650602	1.20632146908244	0.216746408362548	0.675582920642244
GO:0004197	cysteine-type endopeptidase activity	20/3537	88/18639	0.227272727272727	1.19766365949572	0.219165436890943	0.675582920642244
GO:0004535	poly(A)-specific ribonuclease activity	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0008035	high-density lipoprotein particle binding	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0019855	calcium channel inhibitor activity	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0031994	insulin-like growth factor I binding	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0043560	insulin receptor substrate binding	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0070123	transforming growth factor beta receptor activity, type III	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0097157	pre-mRNA intronic binding	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0140333	glycerophospholipid flippase activity	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0140852	histone ubiquitin ligase activity	4/3537	13/18639	0.307692307692308	1.62145233900959	0.221827197258567	0.675582920642244
GO:0004715	non-membrane spanning protein tyrosine kinase activity	11/3537	45/18639	0.244444444444444	1.28815380265762	0.222470171949258	0.675582920642244
GO:0051539	4 iron, 4 sulfur cluster binding	11/3537	45/18639	0.244444444444444	1.28815380265762	0.222470171949258	0.675582920642244
GO:0016411	acylglycerol O-acyltransferase activity	8/3537	31/18639	0.258064516129032	1.35992776820159	0.222708718504581	0.675582920642244
GO:0070273	phosphatidylinositol-4-phosphate binding	8/3537	31/18639	0.258064516129032	1.35992776820159	0.222708718504581	0.675582920642244
GO:0004407	histone deacetylase activity	6/3537	22/18639	0.272727272727273	1.43719639139486	0.227125289916932	0.679875041843856
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	6/3537	22/18639	0.272727272727273	1.43719639139486	0.227125289916932	0.679875041843856
GO:0033558	protein lysine deacetylase activity	6/3537	22/18639	0.272727272727273	1.43719639139486	0.227125289916932	0.679875041843856
GO:0034062	5'-3' RNA polymerase activity	6/3537	22/18639	0.272727272727273	1.43719639139486	0.227125289916932	0.679875041843856
GO:0097747	RNA polymerase activity	6/3537	22/18639	0.272727272727273	1.43719639139486	0.227125289916932	0.679875041843856
GO:0140784	metal ion sensor activity	6/3537	22/18639	0.272727272727273	1.43719639139486	0.227125289916932	0.679875041843856
GO:0045505	dynein intermediate chain binding	9/3537	36/18639	0.25	1.31743002544529	0.232162212447352	0.688883071432207
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	9/3537	36/18639	0.25	1.31743002544529	0.232162212447352	0.688883071432207
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	9/3537	36/18639	0.25	1.31743002544529	0.232162212447352	0.688883071432207
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	9/3537	36/18639	0.25	1.31743002544529	0.232162212447352	0.688883071432207
GO:0008374	O-acyltransferase activity	13/3537	55/18639	0.236363636363636	1.24557020587555	0.233294384513222	0.690734354146991
GO:0042562	hormone binding	21/3537	94/18639	0.223404255319149	1.17727789507877	0.237086512475053	0.700436022725211
GO:0004683	calcium/calmodulin-dependent protein kinase activity	7/3537	27/18639	0.259259259259259	1.36622373009141	0.240860399925841	0.705451042024178
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	7/3537	27/18639	0.259259259259259	1.36622373009141	0.240860399925841	0.705451042024178
GO:0023026	MHC class II protein complex binding	7/3537	27/18639	0.259259259259259	1.36622373009141	0.240860399925841	0.705451042024178
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	7/3537	27/18639	0.259259259259259	1.36622373009141	0.240860399925841	0.705451042024178
GO:0016782	transferase activity, transferring sulphur-containing groups	16/3537	70/18639	0.228571428571429	1.2045074518357	0.243900248288872	0.710752703221797
GO:0004518	nuclease activity	44/3537	209/18639	0.210526315789474	1.10941475826972	0.24488015311455	0.710752703221797
GO:0140767	enzyme-substrate adaptor activity	30/3537	139/18639	0.215827338129496	1.13734966225493	0.245120279457846	0.710752703221797
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/3537	18/18639	0.277777777777778	1.46381113938366	0.24580851399135	0.710752703221797
GO:0015172	acidic amino acid transmembrane transporter activity	5/3537	18/18639	0.277777777777778	1.46381113938366	0.24580851399135	0.710752703221797
GO:0017128	phospholipid scramblase activity	5/3537	18/18639	0.277777777777778	1.46381113938366	0.24580851399135	0.710752703221797
GO:0030246	carbohydrate binding	58/3537	280/18639	0.207142857142857	1.0915848782261	0.248590626749471	0.717271044060576
GO:0022884	macromolecule transmembrane transporter activity	8/3537	32/18639	0.25	1.31743002544529	0.251052096961086	0.718806350899245
GO:0030170	pyridoxal phosphate binding	13/3537	56/18639	0.232142857142857	1.22332788077063	0.254654618664436	0.718806350899245
GO:0170055	lipid transmembrane transporter activity	13/3537	56/18639	0.232142857142857	1.22332788077063	0.254654618664436	0.718806350899245
GO:0101005	deubiquitinase activity	25/3537	115/18639	0.217391304347826	1.14559132647417	0.25689560999485	0.718806350899245
GO:0016836	hydro-lyase activity	14/3537	61/18639	0.229508196721311	1.20944395778584	0.258006480634103	0.718806350899245
GO:0043394	proteoglycan binding	9/3537	37/18639	0.243243243243243	1.28182380854137	0.258839721332792	0.718806350899245
GO:0005283	amino acid:sodium symporter activity	6/3537	23/18639	0.260869565217391	1.374709591769	0.261507618828387	0.718806350899245
GO:0016849	phosphorus-oxygen lyase activity	6/3537	23/18639	0.260869565217391	1.374709591769	0.261507618828387	0.718806350899245
GO:0042171	lysophosphatidic acid acyltransferase activity	6/3537	23/18639	0.260869565217391	1.374709591769	0.261507618828387	0.718806350899245
GO:0071617	lysophospholipid acyltransferase activity	6/3537	23/18639	0.260869565217391	1.374709591769	0.261507618828387	0.718806350899245
GO:0004402	histone acetyltransferase activity	10/3537	42/18639	0.238095238095238	1.25469526232885	0.264916157865613	0.718806350899245
GO:0016859	cis-trans isomerase activity	10/3537	42/18639	0.238095238095238	1.25469526232885	0.264916157865613	0.718806350899245
GO:0019894	kinesin binding	10/3537	42/18639	0.238095238095238	1.25469526232885	0.264916157865613	0.718806350899245
GO:0061630	ubiquitin protein ligase activity	72/3537	353/18639	0.203966005665722	1.07484376013667	0.265365877184587	0.718806350899245
GO:0033192	calmodulin-dependent protein phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:0140791	histone H2AXS140 phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:1990439	MAP kinase serine/threonine phosphatase activity	18/3537	81/18639	0.222222222222222	1.17104891150693	0.26667541037424	0.718806350899245
GO:0004065	arylsulfatase activity	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0005545	1-phosphatidylinositol binding	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0008174	mRNA methyltransferase activity	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0031404	chloride ion binding	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0034236	protein kinase A catalytic subunit binding	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0044548	S100 protein binding	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0070742	C2H2 zinc finger domain binding	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0098821	BMP receptor activity	4/3537	14/18639	0.285714285714286	1.50563431479462	0.267056921555439	0.718806350899245
GO:0061733	protein-lysine-acetyltransferase activity	11/3537	47/18639	0.234042553191489	1.23333874722538	0.269728921174953	0.718806350899245
GO:0061749	forked DNA-dependent helicase activity	11/3537	47/18639	0.234042553191489	1.23333874722538	0.269728921174953	0.718806350899245
GO:0140359	ABC-type transporter activity	11/3537	47/18639	0.234042553191489	1.23333874722538	0.269728921174953	0.718806350899245
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/3537	47/18639	0.234042553191489	1.23333874722538	0.269728921174953	0.718806350899245
GO:0016407	acetyltransferase activity	21/3537	96/18639	0.21875	1.15275127226463	0.27002956847872	0.718806350899245
GO:0015399	primary active transmembrane transporter activity	35/3537	166/18639	0.210843373493976	1.11108556362856	0.271191675195319	0.718806350899245
GO:0015294	solute:monoatomic cation symporter activity	25/3537	116/18639	0.21551724137931	1.13571553917698	0.272110317420069	0.718806350899245
GO:0051019	mitogen-activated protein kinase binding	7/3537	28/18639	0.25	1.31743002544529	0.272470984256866	0.718806350899245
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/3537	28/18639	0.25	1.31743002544529	0.272470984256866	0.718806350899245
GO:0005080	protein kinase C binding	12/3537	52/18639	0.230769230769231	1.21608925425719	0.273580911455738	0.718806350899245
GO:0070279	vitamin B6 binding	13/3537	57/18639	0.228070175438596	1.20186598812553	0.276684982316277	0.718806350899245
GO:0140311	protein sequestering activity	8/3537	33/18639	0.242424242424242	1.2775079034621	0.280450853841293	0.718806350899245
GO:0140416	transcription regulator inhibitor activity	8/3537	33/18639	0.242424242424242	1.2775079034621	0.280450853841293	0.718806350899245
GO:0008173	RNA methyltransferase activity	15/3537	67/18639	0.223880597014925	1.17978808248832	0.281226754915478	0.718806350899245
GO:0042379	chemokine receptor binding	16/3537	72/18639	0.222222222222222	1.17104891150693	0.282866237979406	0.718806350899245
GO:0003724	RNA helicase activity	17/3537	77/18639	0.220779220779221	1.16344469779584	0.28418124770713	0.718806350899245
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	18/3537	82/18639	0.219512195121951	1.15676782722026	0.285224815690679	0.718806350899245
GO:0033549	MAP kinase phosphatase activity	18/3537	82/18639	0.219512195121951	1.15676782722026	0.285224815690679	0.718806350899245
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/3537	19/18639	0.263157894736842	1.38676844783715	0.285389743006601	0.718806350899245
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/3537	19/18639	0.263157894736842	1.38676844783715	0.285389743006601	0.718806350899245
GO:0005520	insulin-like growth factor binding	5/3537	19/18639	0.263157894736842	1.38676844783715	0.285389743006601	0.718806350899245
GO:0042577	lipid phosphatase activity	5/3537	19/18639	0.263157894736842	1.38676844783715	0.285389743006601	0.718806350899245
GO:0008081	phosphoric diester hydrolase activity	19/3537	87/18639	0.218390804597701	1.15085841303267	0.286039245416505	0.718806350899245
GO:0043531	ADP binding	9/3537	38/18639	0.236842105263158	1.24809160305344	0.286421220635329	0.718806350899245
GO:0016922	nuclear receptor binding	29/3537	137/18639	0.211678832116788	1.1154881967274	0.28682905488272	0.718806350899245
GO:0004519	endonuclease activity	27/3537	127/18639	0.21259842519685	1.12033419486686	0.287374174722178	0.718806350899245
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0004382	GDP phosphatase activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0016783	sulfurtransferase activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0030957	Tat protein binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0042975	peroxisome proliferator activated receptor binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0045322	unmethylated CpG binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0047429	nucleoside triphosphate diphosphatase activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0050815	phosphoserine residue binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0051864	histone H3K36 demethylase activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0070097	delta-catenin binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0098505	G-rich strand telomeric DNA binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0099122	RNA polymerase II C-terminal domain binding	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:1990757	ubiquitin ligase activator activity	3/3537	10/18639	0.3	1.58091603053435	0.291493834434188	0.718806350899245
GO:0009378	four-way junction helicase activity	11/3537	48/18639	0.229166666666667	1.20764418999152	0.294475811374899	0.718806350899245
GO:0032266	phosphatidylinositol-3-phosphate binding	11/3537	48/18639	0.229166666666667	1.20764418999152	0.294475811374899	0.718806350899245
GO:0036121	double-stranded DNA helicase activity	11/3537	48/18639	0.229166666666667	1.20764418999152	0.294475811374899	0.718806350899245
GO:0043138	3'-5' DNA helicase activity	11/3537	48/18639	0.229166666666667	1.20764418999152	0.294475811374899	0.718806350899245
GO:0140104	molecular carrier activity	51/3537	249/18639	0.204819277108434	1.0793402618106	0.294494979935571	0.718806350899245
GO:0005315	phosphate transmembrane transporter activity	6/3537	24/18639	0.25	1.31743002544529	0.297107583397317	0.718806350899245
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	6/3537	24/18639	0.25	1.31743002544529	0.297107583397317	0.718806350899245
GO:0070840	dynein complex binding	6/3537	24/18639	0.25	1.31743002544529	0.297107583397317	0.718806350899245
GO:0140612	DNA damage sensor activity	6/3537	24/18639	0.25	1.31743002544529	0.297107583397317	0.718806350899245
GO:0034212	protein N-acetyltransferase activity	12/3537	53/18639	0.226415094339623	1.19314417398819	0.297192351520131	0.718806350899245
GO:0005201	extracellular matrix structural constituent	35/3537	168/18639	0.208333333333333	1.09785835453774	0.297254723477098	0.718806350899245
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	27/3537	128/18639	0.2109375	1.11158158396947	0.302565790873499	0.727355367871112
GO:0022853	active monoatomic ion transmembrane transporter activity	25/3537	118/18639	0.211864406779661	1.11646612325872	0.303506743322106	0.727355367871112
GO:0051213	dioxygenase activity	20/3537	93/18639	0.21505376344086	1.13327314016799	0.304566505097088	0.727355367871112
GO:0051219	phosphoprotein binding	20/3537	93/18639	0.21505376344086	1.13327314016799	0.304566505097088	0.727355367871112
GO:0005416	amino acid:monoatomic cation symporter activity	7/3537	29/18639	0.241379310344828	1.27200140387821	0.305071787848811	0.727355367871112
GO:0035250	UDP-galactosyltransferase activity	7/3537	29/18639	0.241379310344828	1.27200140387821	0.305071787848811	0.727355367871112
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	7/3537	29/18639	0.241379310344828	1.27200140387821	0.305071787848811	0.727355367871112
GO:0099604	ligand-gated calcium channel activity	7/3537	29/18639	0.241379310344828	1.27200140387821	0.305071787848811	0.727355367871112
GO:0004559	alpha-mannosidase activity	4/3537	15/18639	0.266666666666667	1.40525869380831	0.313702427289363	0.738858923199729
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/3537	15/18639	0.266666666666667	1.40525869380831	0.313702427289363	0.738858923199729
GO:0015116	sulfate transmembrane transporter activity	4/3537	15/18639	0.266666666666667	1.40525869380831	0.313702427289363	0.738858923199729
GO:0015929	hexosaminidase activity	4/3537	15/18639	0.266666666666667	1.40525869380831	0.313702427289363	0.738858923199729
GO:0016846	carbon-sulfur lyase activity	4/3537	15/18639	0.266666666666667	1.40525869380831	0.313702427289363	0.738858923199729
GO:0050780	dopamine receptor binding	4/3537	15/18639	0.266666666666667	1.40525869380831	0.313702427289363	0.738858923199729
GO:0140776	protein-containing complex destabilizing activity	4/3537	15/18639	0.266666666666667	1.40525869380831	0.313702427289363	0.738858923199729
GO:0000217	DNA secondary structure binding	9/3537	39/18639	0.230769230769231	1.21608925425719	0.3147314650335	0.74000010550264
GO:0019955	cytokine binding	30/3537	144/18639	0.208333333333333	1.09785835453774	0.315372351427475	0.740226296355679
GO:0016790	thiolester hydrolase activity	10/3537	44/18639	0.227272727272727	1.19766365949572	0.317671475006336	0.744337128506224
GO:0001222	transcription corepressor binding	11/3537	49/18639	0.224489795918367	1.18299839019577	0.319806363568213	0.746764343795878
GO:0060590	ATPase regulator activity	11/3537	49/18639	0.224489795918367	1.18299839019577	0.319806363568213	0.746764343795878
GO:0140463	chromatin-protein adaptor activity	12/3537	54/18639	0.222222222222222	1.17104891150693	0.321336780041498	0.748103299672953
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	13/3537	59/18639	0.220338983050847	1.16112476818907	0.322402612532481	0.748103299672953
GO:0017018	myosin phosphatase activity	18/3537	84/18639	0.214285714285714	1.12922573609596	0.323513257825444	0.748103299672953
GO:0008186	ATP-dependent activity, acting on RNA	17/3537	79/18639	0.215189873417722	1.13399040164911	0.323682663876156	0.748103299672953
GO:0016835	carbon-oxygen lyase activity	17/3537	79/18639	0.215189873417722	1.13399040164911	0.323682663876156	0.748103299672953
GO:0033293	monocarboxylic acid binding	17/3537	79/18639	0.215189873417722	1.13399040164911	0.323682663876156	0.748103299672953
GO:0016408	C-acyltransferase activity	5/3537	20/18639	0.25	1.31743002544529	0.326015701059807	0.750927694870708
GO:0042288	MHC class I protein binding	5/3537	20/18639	0.25	1.31743002544529	0.326015701059807	0.750927694870708
GO:0099106	ion channel regulator activity	33/3537	160/18639	0.20625	1.08687977099237	0.326562375032074	0.750927694870708
GO:0004709	MAP kinase kinase kinase activity	6/3537	25/18639	0.24	1.26473282442748	0.333546100081332	0.759259184240928
GO:0008483	transaminase activity	6/3537	25/18639	0.24	1.26473282442748	0.333546100081332	0.759259184240928
GO:0015271	outward rectifier potassium channel activity	6/3537	25/18639	0.24	1.26473282442748	0.333546100081332	0.759259184240928
GO:0042974	nuclear retinoic acid receptor binding	6/3537	25/18639	0.24	1.26473282442748	0.333546100081332	0.759259184240928
GO:0001221	transcription coregulator binding	24/3537	115/18639	0.208695652173913	1.0997676734152	0.337122550030365	0.759259184240928
GO:0098918	structural constituent of synapse	7/3537	30/18639	0.233333333333333	1.22960135708227	0.338380162090871	0.759259184240928
GO:0000175	3'-5'-RNA exonuclease activity	8/3537	35/18639	0.228571428571429	1.2045074518357	0.341540754828604	0.759259184240928
GO:0005343	organic acid:sodium symporter activity	8/3537	35/18639	0.228571428571429	1.2045074518357	0.341540754828604	0.759259184240928
GO:0016229	steroid dehydrogenase activity	8/3537	35/18639	0.228571428571429	1.2045074518357	0.341540754828604	0.759259184240928
GO:0034061	DNA polymerase activity	8/3537	35/18639	0.228571428571429	1.2045074518357	0.341540754828604	0.759259184240928
GO:0140375	immune receptor activity	32/3537	156/18639	0.205128205128205	1.08096822600639	0.342201393189879	0.759259184240928
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/3537	40/18639	0.225	1.18568702290076	0.343592006377932	0.759259184240928
GO:0071949	FAD binding	9/3537	40/18639	0.225	1.18568702290076	0.343592006377932	0.759259184240928
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	13/3537	60/18639	0.216666666666667	1.14177268871925	0.345905240395842	0.759259184240928
GO:0000099	sulfur amino acid transmembrane transporter activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0002162	dystroglycan binding	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0003953	NAD+ nucleosidase activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0004016	adenylate cyclase activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0004143	ATP-dependent diacylglycerol kinase activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0005114	type II transforming growth factor beta receptor binding	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0005225	volume-sensitive anion channel activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0010854	adenylate cyclase regulator activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0019203	carbohydrate phosphatase activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0019206	nucleoside kinase activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0042608	T cell receptor binding	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0070697	activin receptor binding	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0070990	snRNP binding	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0140537	transcription regulator activator activity	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3537	11/18639	0.272727272727273	1.43719639139486	0.348622318591861	0.759259184240928
GO:0042277	peptide binding	50/3537	249/18639	0.200803212851406	1.0581767272653	0.351981499025468	0.765348571480977
GO:0005126	cytokine receptor binding	55/3537	275/18639	0.2	1.05394402035623	0.354901380501862	0.770464818054362
GO:0003688	DNA replication origin binding	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0004707	MAP kinase activity	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0005159	insulin-like growth factor receptor binding	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0015562	efflux transmembrane transporter activity	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0015923	mannosidase activity	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0097027	ubiquitin-protein transferase activator activity	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0140327	flippase activity	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0140328	floppase activity	4/3537	16/18639	0.25	1.31743002544529	0.360948408753511	0.773704869867542
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	18/3537	86/18639	0.209302325581395	1.10296467246583	0.363034130390875	0.775728589938993
GO:0016209	antioxidant activity	18/3537	86/18639	0.209302325581395	1.10296467246583	0.363034130390875	0.775728589938993
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/3537	21/18639	0.238095238095238	1.25469526232885	0.367164784600055	0.780691210976097
GO:0061891	calcium ion sensor activity	5/3537	21/18639	0.238095238095238	1.25469526232885	0.367164784600055	0.780691210976097
GO:0019783	ubiquitin-like protein peptidase activity	26/3537	127/18639	0.204724409448819	1.07884033579772	0.367473063412936	0.780691210976097
GO:0015026	coreceptor activity	13/3537	61/18639	0.213114754098361	1.12305510365828	0.36971115449798	0.780691210976097
GO:0008198	ferrous iron binding	6/3537	26/18639	0.230769230769231	1.21608925425719	0.370453948148983	0.780691210976097
GO:0030507	spectrin binding	6/3537	26/18639	0.230769230769231	1.21608925425719	0.370453948148983	0.780691210976097
GO:0097602	cullin family protein binding	6/3537	26/18639	0.230769230769231	1.21608925425719	0.370453948148983	0.780691210976097
GO:0019208	phosphatase regulator activity	24/3537	117/18639	0.205128205128205	1.08096822600639	0.371224318553515	0.780691210976097
GO:0005048	signal sequence binding	11/3537	51/18639	0.215686274509804	1.13660629646261	0.371717279183126	0.780691210976097
GO:0004180	carboxypeptidase activity	10/3537	46/18639	0.217391304347826	1.14559132647417	0.372422939695322	0.780691210976097
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	10/3537	46/18639	0.217391304347826	1.14559132647417	0.372422939695322	0.780691210976097
GO:0015175	neutral L-amino acid transmembrane transporter activity	9/3537	41/18639	0.219512195121951	1.15676782722026	0.372824573895134	0.780691210976097
GO:0042287	MHC protein binding	9/3537	41/18639	0.219512195121951	1.15676782722026	0.372824573895134	0.780691210976097
GO:0016853	isomerase activity	36/3537	180/18639	0.2	1.05394402035623	0.3918757608476	0.813711953164297
GO:0004843	cysteine-type deubiquitinase activity	22/3537	108/18639	0.203703703703704	1.07346150221468	0.393214328105539	0.813711953164297
GO:0070851	growth factor receptor binding	28/3537	139/18639	0.201438848920863	1.06152635143793	0.395703592296923	0.813711953164297
GO:0004601	peroxidase activity	12/3537	57/18639	0.210526315789474	1.10941475826972	0.395889353030583	0.813711953164297
GO:0141108	transporter regulator activity	34/3537	170/18639	0.2	1.05394402035623	0.396524672908872	0.813711953164297
GO:0001784	phosphotyrosine residue binding	10/3537	47/18639	0.212765957446809	1.12121704293216	0.400178079835963	0.813711953164297
GO:0005504	fatty acid binding	10/3537	47/18639	0.212765957446809	1.12121704293216	0.400178079835963	0.813711953164297
GO:0000995	RNA polymerase III general transcription initiation factor activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0003995	acyl-CoA dehydrogenase activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0004126	cytidine deaminase activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0004526	ribonuclease P activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0005095	GTPase inhibitor activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0015269	calcium-activated potassium channel activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0016801	hydrolase activity, acting on ether bonds	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0016803	ether hydrolase activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0043047	single-stranded telomeric DNA binding	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0070410	co-SMAD binding	3/3537	12/18639	0.25	1.31743002544529	0.405199458969756	0.813711953164297
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/3537	32/18639	0.21875	1.15275127226463	0.406016025932761	0.813711953164297
GO:0071813	lipoprotein particle binding	7/3537	32/18639	0.21875	1.15275127226463	0.406016025932761	0.813711953164297
GO:0071814	protein-lipid complex binding	7/3537	32/18639	0.21875	1.15275127226463	0.406016025932761	0.813711953164297
GO:0004364	glutathione transferase activity	6/3537	27/18639	0.222222222222222	1.17104891150693	0.407480676212737	0.813711953164297
GO:0005044	scavenger receptor activity	6/3537	27/18639	0.222222222222222	1.17104891150693	0.407480676212737	0.813711953164297
GO:0008266	poly(U) RNA binding	6/3537	27/18639	0.222222222222222	1.17104891150693	0.407480676212737	0.813711953164297
GO:0008320	protein transmembrane transporter activity	6/3537	27/18639	0.222222222222222	1.17104891150693	0.407480676212737	0.813711953164297
GO:0015278	intracellularly gated calcium channel activity	4/3537	17/18639	0.235294117647059	1.23993414159557	0.408065785383336	0.813711953164297
GO:0030169	low-density lipoprotein particle binding	4/3537	17/18639	0.235294117647059	1.23993414159557	0.408065785383336	0.813711953164297
GO:0032977	membrane insertase activity	4/3537	17/18639	0.235294117647059	1.23993414159557	0.408065785383336	0.813711953164297
GO:0051787	misfolded protein binding	4/3537	17/18639	0.235294117647059	1.23993414159557	0.408065785383336	0.813711953164297
GO:1990226	histone methyltransferase binding	4/3537	17/18639	0.235294117647059	1.23993414159557	0.408065785383336	0.813711953164297
GO:0008649	rRNA methyltransferase activity	5/3537	22/18639	0.227272727272727	1.19766365949572	0.408352871271561	0.813711953164297
GO:0005548	phospholipid transporter activity	14/3537	68/18639	0.205882352941176	1.08494237389612	0.414747837812268	0.825244965720164
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	12/3537	58/18639	0.206896551724138	1.0902869176099	0.421087092916943	0.835412203319892
GO:0017116	single-stranded DNA helicase activity	12/3537	58/18639	0.206896551724138	1.0902869176099	0.421087092916943	0.835412203319892
GO:0003727	single-stranded RNA binding	18/3537	89/18639	0.202247191011236	1.06578608800069	0.423664006381465	0.839299394566197
GO:0004860	protein kinase inhibitor activity	17/3537	84/18639	0.202380952380952	1.06649097297952	0.427007914708439	0.844692512501846
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	10/3537	48/18639	0.208333333333333	1.09785835453774	0.427994466273085	0.845413487885353
GO:0008200	ion channel inhibitor activity	9/3537	43/18639	0.209302325581395	1.10296467246583	0.431711636206757	0.851518307118987
GO:0048029	monosaccharide binding	15/3537	74/18639	0.202702702702703	1.0681865071178	0.434141703777888	0.855070399179927
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	8/3537	38/18639	0.210526315789474	1.10941475826972	0.435641638898399	0.856782904866749
GO:0008080	N-acetyltransferase activity	14/3537	69/18639	0.202898550724638	1.06921857137589	0.437970338058936	0.860118048297824
GO:0016247	channel regulator activity	33/3537	168/18639	0.196428571428571	1.0351235914213	0.443443688148323	0.863237154057407
GO:0019210	kinase inhibitor activity	18/3537	90/18639	0.2	1.05394402035623	0.444012705932998	0.863237154057407
GO:0046875	ephrin receptor binding	6/3537	28/18639	0.214285714285714	1.12922573609596	0.444301501291612	0.863237154057407
GO:0050698	proteoglycan sulfotransferase activity	6/3537	28/18639	0.214285714285714	1.12922573609596	0.444301501291612	0.863237154057407
GO:0051119	sugar transmembrane transporter activity	6/3537	28/18639	0.214285714285714	1.12922573609596	0.444301501291612	0.863237154057407
GO:0004879	nuclear receptor activity	12/3537	59/18639	0.203389830508475	1.07180747832837	0.446283130461912	0.863237154057407
GO:0015459	potassium channel regulator activity	12/3537	59/18639	0.203389830508475	1.07180747832837	0.446283130461912	0.863237154057407
GO:0070888	E-box binding	12/3537	59/18639	0.203389830508475	1.07180747832837	0.446283130461912	0.863237154057407
GO:0000295	adenine nucleotide transmembrane transporter activity	5/3537	23/18639	0.217391304347826	1.14559132647417	0.449143219172442	0.863237154057407
GO:0004022	alcohol dehydrogenase (NAD+) activity	5/3537	23/18639	0.217391304347826	1.14559132647417	0.449143219172442	0.863237154057407
GO:0043274	phospholipase binding	5/3537	23/18639	0.217391304347826	1.14559132647417	0.449143219172442	0.863237154057407
GO:0140102	catalytic activity, acting on a rRNA	5/3537	23/18639	0.217391304347826	1.14559132647417	0.449143219172442	0.863237154057407
GO:0140103	catalytic activity, acting on a glycoprotein	5/3537	23/18639	0.217391304347826	1.14559132647417	0.449143219172442	0.863237154057407
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/3537	54/18639	0.203703703703704	1.07346150221468	0.450841291713701	0.863237154057407
GO:0003774	cytoskeletal motor activity	30/3537	153/18639	0.196078431372549	1.03327845132964	0.453277270158652	0.863237154057407
GO:0061775	cohesin loader activity	30/3537	153/18639	0.196078431372549	1.03327845132964	0.453277270158652	0.863237154057407
GO:0004706	JUN kinase kinase kinase activity	4/3537	18/18639	0.222222222222222	1.17104891150693	0.454425005781046	0.863237154057407
GO:0004970	glutamate-gated receptor activity	4/3537	18/18639	0.222222222222222	1.17104891150693	0.454425005781046	0.863237154057407
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/3537	18/18639	0.222222222222222	1.17104891150693	0.454425005781046	0.863237154057407
GO:0050811	GABA receptor binding	4/3537	18/18639	0.222222222222222	1.17104891150693	0.454425005781046	0.863237154057407
GO:0070064	proline-rich region binding	4/3537	18/18639	0.222222222222222	1.17104891150693	0.454425005781046	0.863237154057407
GO:0070628	proteasome binding	4/3537	18/18639	0.222222222222222	1.17104891150693	0.454425005781046	0.863237154057407
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3537	18/18639	0.222222222222222	1.17104891150693	0.454425005781046	0.863237154057407
GO:0004465	lipoprotein lipase activity	3/3537	13/18639	0.230769230769231	1.21608925425719	0.460211137483113	0.863237154057407
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/3537	13/18639	0.230769230769231	1.21608925425719	0.460211137483113	0.863237154057407
GO:0017154	semaphorin receptor activity	3/3537	13/18639	0.230769230769231	1.21608925425719	0.460211137483113	0.863237154057407
GO:0035673	oligopeptide transmembrane transporter activity	3/3537	13/18639	0.230769230769231	1.21608925425719	0.460211137483113	0.863237154057407
GO:0051011	microtubule minus-end binding	3/3537	13/18639	0.230769230769231	1.21608925425719	0.460211137483113	0.863237154057407
GO:0070700	BMP receptor binding	3/3537	13/18639	0.230769230769231	1.21608925425719	0.460211137483113	0.863237154057407
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/3537	13/18639	0.230769230769231	1.21608925425719	0.460211137483113	0.863237154057407
GO:0016248	channel inhibitor activity	9/3537	44/18639	0.204545454545455	1.07789729354615	0.461036249086864	0.863237154057407
GO:0043014	alpha-tubulin binding	9/3537	44/18639	0.204545454545455	1.07789729354615	0.461036249086864	0.863237154057407
GO:0008028	monocarboxylic acid transmembrane transporter activity	14/3537	70/18639	0.2	1.05394402035623	0.461155389143251	0.863237154057407
GO:0097110	scaffold protein binding	14/3537	70/18639	0.2	1.05394402035623	0.461155389143251	0.863237154057407
GO:0120013	lipid transfer activity	13/3537	65/18639	0.2	1.05394402035623	0.466092713155867	0.871279225830569
GO:0004857	enzyme inhibitor activity	80/3537	416/18639	0.192307692307692	1.01340771188099	0.466907718762148	0.871603832139779
GO:0001098	basal transcription machinery binding	12/3537	60/18639	0.2	1.05394402035623	0.471377602978429	0.876336747534453
GO:0001099	basal RNA polymerase II transcription machinery binding	12/3537	60/18639	0.2	1.05394402035623	0.471377602978429	0.876336747534453
GO:0098531	ligand-modulated transcription factor activity	12/3537	60/18639	0.2	1.05394402035623	0.471377602978429	0.876336747534453
GO:0015035	protein-disulfide reductase activity	7/3537	34/18639	0.205882352941176	1.08494237389612	0.473301396023963	0.878711198355964
GO:0140313	molecular sequestering activity	11/3537	55/18639	0.2	1.05394402035623	0.477074926920477	0.883942855612738
GO:0140101	catalytic activity, acting on a tRNA	27/3537	139/18639	0.194244604316547	1.02361469602944	0.480510260660624	0.883942855612738
GO:0003785	actin monomer binding	6/3537	29/18639	0.206896551724138	1.0902869176099	0.480622296102777	0.883942855612738
GO:0004181	metallocarboxypeptidase activity	6/3537	29/18639	0.206896551724138	1.0902869176099	0.480622296102777	0.883942855612738
GO:0051861	glycolipid binding	6/3537	29/18639	0.206896551724138	1.0902869176099	0.480622296102777	0.883942855612738
GO:0003689	DNA clamp loader activity	31/3537	160/18639	0.19375	1.0210082697201	0.480639950632391	0.883942855612738
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	35/3537	181/18639	0.193370165745856	1.0190066495157	0.480672384325102	0.883942855612738
GO:0052689	carboxylic ester hydrolase activity	18/3537	92/18639	0.195652173913043	1.03103219382675	0.48459595531578	0.887527876280207
GO:0005125	cytokine activity	45/3537	234/18639	0.192307692307692	1.01340771188099	0.486855926913906	0.887527876280207
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0004806	triacylglycerol lipase activity	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0015149	hexose transmembrane transporter activity	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0050699	WW domain binding	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0055056	D-glucose transmembrane transporter activity	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0070300	phosphatidic acid binding	5/3537	24/18639	0.208333333333333	1.09785835453774	0.489152597008002	0.887527876280207
GO:0141110	transporter inhibitor activity	9/3537	45/18639	0.2	1.05394402035623	0.490077349531492	0.888020157351063
GO:0008234	cysteine-type peptidase activity	36/3537	187/18639	0.192513368983957	1.01449157039638	0.491328491665575	0.889101757887506
GO:0004866	endopeptidase inhibitor activity	31/3537	161/18639	0.192546583850932	1.01466660344855	0.49595506086432	0.890218864764236
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	12/3537	61/18639	0.19672131147541	1.03666624953072	0.496275508728743	0.890218864764236
GO:0004532	RNA exonuclease activity	8/3537	40/18639	0.2	1.05394402035623	0.497657328920418	0.890218864764236
GO:0015036	disulfide oxidoreductase activity	8/3537	40/18639	0.2	1.05394402035623	0.497657328920418	0.890218864764236
GO:0015144	carbohydrate transmembrane transporter activity	8/3537	40/18639	0.2	1.05394402035623	0.497657328920418	0.890218864764236
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/3537	19/18639	0.210526315789474	1.10941475826972	0.499501075854232	0.890218864764236
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/3537	19/18639	0.210526315789474	1.10941475826972	0.499501075854232	0.890218864764236
GO:0031420	alkali metal ion binding	4/3537	19/18639	0.210526315789474	1.10941475826972	0.499501075854232	0.890218864764236
GO:0043395	heparan sulfate proteoglycan binding	4/3537	19/18639	0.210526315789474	1.10941475826972	0.499501075854232	0.890218864764236
GO:1990380	K48-linked deubiquitinase activity	4/3537	19/18639	0.210526315789474	1.10941475826972	0.499501075854232	0.890218864764236
GO:0140297	DNA-binding transcription factor binding	93/3537	488/18639	0.190573770491803	1.00427042923289	0.50029737358537	0.890218864764236
GO:0000510	H3-H4 histone complex chaperone activity	29/3537	151/18639	0.19205298013245	1.01206545001095	0.504321215119037	0.890218864764236
GO:0140584	chromatin extrusion motor activity	29/3537	151/18639	0.19205298013245	1.01206545001095	0.504321215119037	0.890218864764236
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	29/3537	151/18639	0.19205298013245	1.01206545001095	0.504321215119037	0.890218864764236
GO:0140849	ATP-dependent H2AZ histone chaperone activity	29/3537	151/18639	0.19205298013245	1.01206545001095	0.504321215119037	0.890218864764236
GO:0016298	lipase activity	25/3537	130/18639	0.192307692307692	1.01340771188099	0.505966392749147	0.890218864764236
GO:0004620	phospholipase activity	21/3537	109/18639	0.192660550458716	1.01526717557252	0.507940944880119	0.890218864764236
GO:0016651	oxidoreductase activity, acting on NAD(P)H	17/3537	88/18639	0.193181818181818	1.01801411057136	0.510416186926111	0.890218864764236
GO:0004705	JUN kinase activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0005313	L-glutamate transmembrane transporter activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0005347	ATP transmembrane transporter activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0008474	palmitoyl-(protein) hydrolase activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0015926	glucosidase activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0019992	diacylglycerol binding	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0030983	mismatched DNA binding	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0032454	histone H3K9 demethylase activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0043176	amine binding	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0098599	palmitoyl hydrolase activity	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0098847	sequence-specific single stranded DNA binding	3/3537	14/18639	0.214285714285714	1.12922573609596	0.512889560008841	0.890218864764236
GO:0004175	endopeptidase activity	77/3537	405/18639	0.190123456790123	1.00189740206704	0.513039221948611	0.890218864764236
GO:0008187	poly-pyrimidine tract binding	6/3537	30/18639	0.2	1.05394402035623	0.516182829605753	0.890218864764236
GO:0015215	nucleotide transmembrane transporter activity	6/3537	30/18639	0.2	1.05394402035623	0.516182829605753	0.890218864764236
GO:0016769	transferase activity, transferring nitrogenous groups	6/3537	30/18639	0.2	1.05394402035623	0.516182829605753	0.890218864764236
GO:0022839	monoatomic ion-gated channel activity	6/3537	30/18639	0.2	1.05394402035623	0.516182829605753	0.890218864764236
GO:0033612	receptor serine/threonine kinase binding	6/3537	30/18639	0.2	1.05394402035623	0.516182829605753	0.890218864764236
GO:0030291	protein serine/threonine kinase inhibitor activity	9/3537	46/18639	0.195652173913043	1.03103219382675	0.518695989761911	0.893419328373177
GO:0015616	DNA translocase activity	29/3537	152/18639	0.190789473684211	1.00540712468193	0.520042516160866	0.893473804630362
GO:0140674	ATP-dependent histone chaperone activity	29/3537	152/18639	0.190789473684211	1.00540712468193	0.520042516160866	0.893473804630362
GO:0061135	endopeptidase regulator activity	35/3537	184/18639	0.190217391304348	1.0023924106649	0.52372719793776	0.898668260097747
GO:0015645	fatty acid ligase activity	5/3537	25/18639	0.2	1.05394402035623	0.528054221239669	0.899280309103648
GO:0015662	P-type ion transporter activity	5/3537	25/18639	0.2	1.05394402035623	0.528054221239669	0.899280309103648
GO:0019211	phosphatase activator activity	5/3537	25/18639	0.2	1.05394402035623	0.528054221239669	0.899280309103648
GO:0047617	fatty acyl-CoA hydrolase activity	5/3537	25/18639	0.2	1.05394402035623	0.528054221239669	0.899280309103648
GO:0120515	fatty acid-CoA ligase activity	5/3537	25/18639	0.2	1.05394402035623	0.528054221239669	0.899280309103648
GO:0140358	P-type transmembrane transporter activity	5/3537	25/18639	0.2	1.05394402035623	0.528054221239669	0.899280309103648
GO:0140658	ATP-dependent chromatin remodeler activity	30/3537	158/18639	0.189873417721519	1.00057976616098	0.530938334507173	0.903060321145491
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	66/3537	349/18639	0.189111747851003	0.996565979133402	0.53450290147532	0.9079868038812
GO:0030414	peptidase inhibitor activity	32/3537	169/18639	0.189349112426035	0.997816824005902	0.536804229237289	0.909016655500536
GO:0004527	exonuclease activity	16/3537	84/18639	0.19047619047619	1.00375620986308	0.537490885898146	0.909016655500536
GO:0015078	proton transmembrane transporter activity	35/3537	185/18639	0.189189189189189	0.996974073309951	0.537927800032978	0.909016655500536
GO:0000993	RNA polymerase II complex binding	7/3537	36/18639	0.194444444444444	1.02466779756856	0.538453574450281	0.909016655500536
GO:0004190	aspartic-type endopeptidase activity	7/3537	36/18639	0.194444444444444	1.02466779756856	0.538453574450281	0.909016655500536
GO:0001972	retinoic acid binding	4/3537	20/18639	0.2	1.05394402035623	0.542872419552838	0.911945139891603
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	4/3537	20/18639	0.2	1.05394402035623	0.542872419552838	0.911945139891603
GO:0030742	GTP-dependent protein binding	4/3537	20/18639	0.2	1.05394402035623	0.542872419552838	0.911945139891603
GO:0061608	nuclear import signal receptor activity	4/3537	20/18639	0.2	1.05394402035623	0.542872419552838	0.911945139891603
GO:0001664	G protein-coupled receptor binding	56/3537	297/18639	0.188552188552189	0.993617258248301	0.545166712052905	0.911982380965417
GO:0005164	tumor necrosis factor receptor binding	6/3537	31/18639	0.193548387096774	1.01994582615119	0.550758468758284	0.911982380965417
GO:0005310	dicarboxylic acid transmembrane transporter activity	6/3537	31/18639	0.193548387096774	1.01994582615119	0.550758468758284	0.911982380965417
GO:0005452	solute:inorganic anion antiporter activity	6/3537	31/18639	0.193548387096774	1.01994582615119	0.550758468758284	0.911982380965417
GO:0016878	acid-thiol ligase activity	6/3537	31/18639	0.193548387096774	1.01994582615119	0.550758468758284	0.911982380965417
GO:0015103	inorganic anion transmembrane transporter activity	31/3537	165/18639	0.187878787878788	0.990068625183129	0.556364541116142	0.911982380965417
GO:0000774	adenyl-nucleotide exchange factor activity	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0008242	omega peptidase activity	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0017081	chloride channel regulator activity	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0031005	filamin binding	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0140161	monocarboxylate:sodium symporter activity	3/3537	15/18639	0.2	1.05394402035623	0.562686343188711	0.911982380965417
GO:0005246	calcium channel regulator activity	10/3537	53/18639	0.188679245283019	0.994286811656825	0.563476585867734	0.911982380965417
GO:0005544	calcium-dependent phospholipid binding	10/3537	53/18639	0.188679245283019	0.994286811656825	0.563476585867734	0.911982380965417
GO:0008146	sulfotransferase activity	10/3537	53/18639	0.188679245283019	0.994286811656825	0.563476585867734	0.911982380965417
GO:0004112	cyclic-nucleotide phosphodiesterase activity	5/3537	26/18639	0.192307692307692	1.01340771188099	0.565578095785071	0.911982380965417
GO:0005227	calcium-activated cation channel activity	5/3537	26/18639	0.192307692307692	1.01340771188099	0.565578095785071	0.911982380965417
GO:0008066	glutamate receptor activity	5/3537	26/18639	0.192307692307692	1.01340771188099	0.565578095785071	0.911982380965417
GO:0015145	monosaccharide transmembrane transporter activity	5/3537	26/18639	0.192307692307692	1.01340771188099	0.565578095785071	0.911982380965417
GO:0015216	purine nucleotide transmembrane transporter activity	5/3537	26/18639	0.192307692307692	1.01340771188099	0.565578095785071	0.911982380965417
GO:0016289	acyl-CoA hydrolase activity	5/3537	26/18639	0.192307692307692	1.01340771188099	0.565578095785071	0.911982380965417
GO:0050681	nuclear androgen receptor binding	5/3537	26/18639	0.192307692307692	1.01340771188099	0.565578095785071	0.911982380965417
GO:0048306	calcium-dependent protein binding	15/3537	80/18639	0.1875	0.988072519083969	0.565836503293717	0.911982380965417
GO:0004386	helicase activity	29/3537	155/18639	0.187096774193548	0.985947631946155	0.566476925099511	0.911982380965417
GO:0003924	GTPase activity	62/3537	331/18639	0.187311178247734	0.987077481300401	0.568197561122794	0.911982380965417
GO:0019888	protein phosphatase regulator activity	20/3537	107/18639	0.186915887850467	0.984994411547882	0.569159077362554	0.911982380965417
GO:0070001	aspartic-type peptidase activity	7/3537	37/18639	0.189189189189189	0.996974073309951	0.569773151888468	0.911982380965417
GO:0072341	modified amino acid binding	17/3537	91/18639	0.186813186813187	0.984453205827252	0.571072032581444	0.911982380965417
GO:0016879	ligase activity, forming carbon-nitrogen bonds	9/3537	48/18639	0.1875	0.988072519083969	0.57417484139564	0.911982380965417
GO:0140597	protein carrier chaperone	35/3537	188/18639	0.186170212765957	0.981064912565643	0.57984010226475	0.911982380965417
GO:0009975	cyclase activity	4/3537	21/18639	0.19047619047619	1.00375620986308	0.584215392482905	0.911982380965417
GO:0010314	phosphatidylinositol-5-phosphate binding	4/3537	21/18639	0.19047619047619	1.00375620986308	0.584215392482905	0.911982380965417
GO:0015125	bile acid transmembrane transporter activity	4/3537	21/18639	0.19047619047619	1.00375620986308	0.584215392482905	0.911982380965417
GO:0035613	RNA stem-loop binding	4/3537	21/18639	0.19047619047619	1.00375620986308	0.584215392482905	0.911982380965417
GO:0036122	BMP binding	4/3537	21/18639	0.19047619047619	1.00375620986308	0.584215392482905	0.911982380965417
GO:0072542	protein phosphatase activator activity	4/3537	21/18639	0.19047619047619	1.00375620986308	0.584215392482905	0.911982380965417
GO:0016874	ligase activity	31/3537	167/18639	0.18562874251497	0.978211515899499	0.585776922184638	0.911982380965417
GO:0030971	receptor tyrosine kinase binding	15/3537	81/18639	0.185185185185185	0.975874092922439	0.586774361451877	0.911982380965417
GO:0000182	rDNA binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0005345	purine nucleobase transmembrane transporter activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0005522	profilin binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0008140	cAMP response element binding protein binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0008190	eukaryotic initiation factor 4E binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0008401	retinoic acid 4-hydroxylase activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0008519	ammonium channel activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0015187	glycine transmembrane transporter activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0015203	polyamine transmembrane transporter activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0016868	intramolecular phosphotransferase activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0019531	oxalate transmembrane transporter activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0031419	cobalamin binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0031434	mitogen-activated protein kinase kinase binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0033204	ribonuclease P RNA binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0035256	G protein-coupled glutamate receptor binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0043121	neurotrophin binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0043208	glycosphingolipid binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0043295	glutathione binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0043422	protein kinase B binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0050308	sugar-phosphatase activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0051378	serotonin binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0070513	death domain binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0140135	mechanosensitive monoatomic cation channel activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0140940	histone H2A methyltransferase activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0141109	transporter activator activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:1905394	retromer complex binding	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:1990259	histone H2AQ104 methyltransferase activity	2/3537	10/18639	0.2	1.05394402035623	0.592553673577972	0.911982380965417
GO:0051536	iron-sulfur cluster binding	14/3537	76/18639	0.184210526315789	0.970737913486005	0.59545423908337	0.913353269363944
GO:0098631	cell adhesion mediator activity	14/3537	76/18639	0.184210526315789	0.970737913486005	0.59545423908337	0.913353269363944
GO:1901681	sulfur compound binding	51/3537	275/18639	0.185454545454545	0.977293546148508	0.597310871745302	0.913353269363944
GO:0000146	microfilament motor activity	7/3537	38/18639	0.184210526315789	0.970737913486005	0.600060912886225	0.913353269363944
GO:0005501	retinoid binding	7/3537	38/18639	0.184210526315789	0.970737913486005	0.600060912886225	0.913353269363944
GO:0019840	isoprenoid binding	7/3537	38/18639	0.184210526315789	0.970737913486005	0.600060912886225	0.913353269363944
GO:0042162	telomeric DNA binding	7/3537	38/18639	0.184210526315789	0.970737913486005	0.600060912886225	0.913353269363944
GO:0042887	amide transmembrane transporter activity	7/3537	38/18639	0.184210526315789	0.970737913486005	0.600060912886225	0.913353269363944
GO:0001671	ATPase activator activity	5/3537	27/18639	0.185185185185185	0.975874092922439	0.601509327506056	0.913353269363944
GO:0008395	steroid hydroxylase activity	5/3537	27/18639	0.185185185185185	0.975874092922439	0.601509327506056	0.913353269363944
GO:0015252	proton channel activity	5/3537	27/18639	0.185185185185185	0.975874092922439	0.601509327506056	0.913353269363944
GO:0016405	CoA-ligase activity	5/3537	27/18639	0.185185185185185	0.975874092922439	0.601509327506056	0.913353269363944
GO:0000062	fatty-acyl-CoA binding	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0004708	MAP kinase kinase activity	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0005521	lamin binding	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0008142	oxysterol binding	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0022841	potassium ion leak channel activity	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0055102	lipase inhibitor activity	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	3/3537	16/18639	0.1875	0.988072519083969	0.609241251135296	0.914871668831897
GO:0098632	cell-cell adhesion mediator activity	10/3537	55/18639	0.181818181818182	0.958130927596576	0.613964536232133	0.9209468043482
GO:0051540	metal cluster binding	14/3537	77/18639	0.181818181818182	0.958130927596576	0.616456736941032	0.923665606949132
GO:0140713	histone chaperone activity	30/3537	164/18639	0.182926829268293	0.963973189350214	0.62010060035095	0.928102109996631
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/3537	22/18639	0.181818181818182	0.958130927596576	0.623295952752092	0.929812513490771
GO:0050321	tau-protein kinase activity	4/3537	22/18639	0.181818181818182	0.958130927596576	0.623295952752092	0.929812513490771
GO:0061133	endopeptidase activator activity	4/3537	22/18639	0.181818181818182	0.958130927596576	0.623295952752092	0.929812513490771
GO:0015108	chloride transmembrane transporter activity	22/3537	121/18639	0.181818181818182	0.958130927596576	0.624910835843791	0.931199370517228
GO:0032813	tumor necrosis factor receptor superfamily binding	9/3537	50/18639	0.18	0.948549618320611	0.626628324913665	0.932735918464043
GO:0042826	histone deacetylase binding	23/3537	127/18639	0.181102362204724	0.954358758590291	0.634091322244711	0.935173027273273
GO:0016866	intramolecular transferase activity	5/3537	28/18639	0.178571428571429	0.941021446746638	0.635684941900501	0.935173027273273
GO:0141052	histone H3 demethylase activity	5/3537	28/18639	0.178571428571429	0.941021446746638	0.635684941900501	0.935173027273273
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0005536	D-glucose binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0008046	axon guidance receptor activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0008199	ferric iron binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0008432	JUN kinase binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0015173	aromatic amino acid transmembrane transporter activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0015205	nucleobase transmembrane transporter activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0015217	ADP transmembrane transporter activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0016594	glycine binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0019215	intermediate filament binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0034056	estrogen response element binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0035252	UDP-xylosyltransferase activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0042285	xylosyltransferase activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0047676	arachidonate-CoA ligase activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0048407	platelet-derived growth factor binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0097493	structural molecule activity conferring elasticity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:1900750	oligopeptide binding	2/3537	11/18639	0.181818181818182	0.958130927596576	0.646760641352663	0.935173027273273
GO:0016831	carboxy-lyase activity	6/3537	34/18639	0.176470588235294	0.929950606196677	0.646864602582986	0.935173027273273
GO:1990782	protein tyrosine kinase binding	21/3537	117/18639	0.179487179487179	0.945847197755595	0.648705465302608	0.935173027273273
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:0008429	phosphatidylethanolamine binding	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:0030548	acetylcholine receptor regulator activity	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:0032183	SUMO binding	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:0036041	long-chain fatty acid binding	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:0045236	CXCR chemokine receptor binding	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:1901567	fatty acid derivative binding	3/3537	17/18639	0.176470588235294	0.929950606196677	0.652350279510716	0.935173027273273
GO:0008201	heparin binding	31/3537	172/18639	0.180232558139535	0.949775134623351	0.655866660465274	0.938031879476869
GO:0015370	solute:sodium symporter activity	14/3537	79/18639	0.177215189873418	0.933874448416916	0.656833724521297	0.938031879476869
GO:0004177	aminopeptidase activity	7/3537	40/18639	0.175	0.922201017811705	0.657105481428977	0.938031879476869
GO:0050997	quaternary ammonium group binding	7/3537	40/18639	0.175	0.922201017811705	0.657105481428977	0.938031879476869
GO:0008171	O-methyltransferase activity	4/3537	23/18639	0.173913043478261	0.916473061179334	0.659959686137281	0.939146820377554
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3537	23/18639	0.173913043478261	0.916473061179334	0.659959686137281	0.939146820377554
GO:0099186	structural constituent of postsynapse	4/3537	23/18639	0.173913043478261	0.916473061179334	0.659959686137281	0.939146820377554
GO:0003678	DNA helicase activity	13/3537	74/18639	0.175675675675676	0.925761639502098	0.667542094647022	0.948943207767053
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	16/3537	91/18639	0.175824175824176	0.926544193719766	0.67432789087587	0.955749289097955
GO:0008137	NADH dehydrogenase (ubiquinone) activity	7/3537	41/18639	0.170731707317073	0.8997083100602	0.683702530402294	0.955749289097955
GO:0016877	ligase activity, forming carbon-sulfur bonds	7/3537	41/18639	0.170731707317073	0.8997083100602	0.683702530402294	0.955749289097955
GO:0140318	protein transporter activity	7/3537	41/18639	0.170731707317073	0.8997083100602	0.683702530402294	0.955749289097955
GO:0008408	3'-5' exonuclease activity	10/3537	58/18639	0.172413793103448	0.908572431341581	0.683743965861248	0.955749289097955
GO:0044325	transmembrane transporter binding	24/3537	136/18639	0.176470588235294	0.929950606196677	0.68773442963003	0.955749289097955
GO:0005253	monoatomic anion channel activity	18/3537	103/18639	0.174757281553398	0.920921959534573	0.690014474540661	0.955749289097955
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0008308	voltage-gated monoatomic anion channel activity	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0008525	phosphatidylcholine transporter activity	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0015280	ligand-gated sodium channel activity	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0031690	adrenergic receptor binding	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0034185	apolipoprotein binding	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0099602	neurotransmitter receptor regulator activity	3/3537	18/18639	0.166666666666667	0.878286683630195	0.691935334256649	0.955749289097955
GO:0048027	mRNA 5'-UTR binding	4/3537	24/18639	0.166666666666667	0.878286683630195	0.694121103963136	0.955749289097955
GO:0050431	transforming growth factor beta binding	4/3537	24/18639	0.166666666666667	0.878286683630195	0.694121103963136	0.955749289097955
GO:0005247	voltage-gated chloride channel activity	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0005436	sodium:phosphate symporter activity	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0015166	polyol transmembrane transporter activity	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0016273	arginine N-methyltransferase activity	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0016274	protein-arginine N-methyltransferase activity	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0016423	tRNA (guanine) methyltransferase activity	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0035259	nuclear glucocorticoid receptor binding	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0036009	protein-glutamine N-methyltransferase activity	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0042301	phosphate ion binding	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0070679	inositol 1,4,5 trisphosphate binding	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0097677	STAT family protein binding	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/3537	12/18639	0.166666666666667	0.878286683630195	0.695072877829245	0.955749289097955
GO:0031072	heat shock protein binding	23/3537	131/18639	0.175572519083969	0.925218033137152	0.695166656359218	0.955749289097955
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/3537	53/18639	0.169811320754717	0.894858130491142	0.698335350629306	0.955749289097955
GO:0140296	general transcription initiation factor binding	9/3537	53/18639	0.169811320754717	0.894858130491142	0.698335350629306	0.955749289097955
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/3537	30/18639	0.166666666666667	0.878286683630195	0.698351025808881	0.955749289097955
GO:0031210	phosphatidylcholine binding	5/3537	30/18639	0.166666666666667	0.878286683630195	0.698351025808881	0.955749289097955
GO:0032452	histone demethylase activity	5/3537	30/18639	0.166666666666667	0.878286683630195	0.698351025808881	0.955749289097955
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/3537	30/18639	0.166666666666667	0.878286683630195	0.698351025808881	0.955749289097955
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/3537	36/18639	0.166666666666667	0.878286683630195	0.703460116246537	0.96080632962718
GO:0055106	ubiquitin-protein transferase regulator activity	6/3537	36/18639	0.166666666666667	0.878286683630195	0.703460116246537	0.96080632962718
GO:0001786	phosphatidylserine binding	10/3537	59/18639	0.169491525423729	0.893172898606978	0.705218933521959	0.961276359735548
GO:0036002	pre-mRNA binding	10/3537	59/18639	0.169491525423729	0.893172898606978	0.705218933521959	0.961276359735548
GO:0004520	DNA endonuclease activity	7/3537	42/18639	0.166666666666667	0.878286683630195	0.708945394751958	0.962494297170741
GO:0008307	structural constituent of muscle	7/3537	42/18639	0.166666666666667	0.878286683630195	0.708945394751958	0.962494297170741
GO:0035198	miRNA binding	7/3537	42/18639	0.166666666666667	0.878286683630195	0.708945394751958	0.962494297170741
GO:0043175	RNA polymerase core enzyme binding	7/3537	42/18639	0.166666666666667	0.878286683630195	0.708945394751958	0.962494297170741
GO:0003697	single-stranded DNA binding	21/3537	121/18639	0.173553719008264	0.914579521796732	0.710912520295723	0.964201711658571
GO:0008509	monoatomic anion transmembrane transporter activity	26/3537	149/18639	0.174496644295302	0.919548474136312	0.71483027405744	0.966862335489626
GO:0008094	ATP-dependent activity, acting on DNA	37/3537	210/18639	0.176190476190476	0.928474494123349	0.719415888048444	0.966862335489626
GO:0050661	NADP binding	9/3537	54/18639	0.166666666666667	0.878286683630195	0.72018731748371	0.966862335489626
GO:0016410	N-acyltransferase activity	16/3537	94/18639	0.170212765957447	0.896973634345731	0.725454028190016	0.966862335489626
GO:0005251	delayed rectifier potassium channel activity	4/3537	25/18639	0.16	0.843155216284987	0.725752891148559	0.966862335489626
GO:0072349	modified amino acid transmembrane transporter activity	5/3537	31/18639	0.161290322580645	0.849954855125995	0.726734209857073	0.966862335489626
GO:0140457	protein demethylase activity	5/3537	31/18639	0.161290322580645	0.849954855125995	0.726734209857073	0.966862335489626
GO:0005229	intracellularly calcium-gated chloride channel activity	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0016918	retinal binding	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0022840	leak channel activity	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0022842	narrow pore channel activity	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0030506	ankyrin binding	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0034987	immunoglobulin receptor binding	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0046624	sphingolipid transporter activity	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0070003	threonine-type peptidase activity	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0097001	ceramide binding	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0120227	acyl-CoA binding	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0141147	intracellularly calcium-gated channel activity	3/3537	19/18639	0.157894736842105	0.83206106870229	0.728016757707103	0.966862335489626
GO:0005254	chloride channel activity	14/3537	83/18639	0.168674698795181	0.888868450902848	0.730178153227108	0.966862335489626
GO:0051087	protein-folding chaperone binding	23/3537	134/18639	0.171641791044776	0.90450419657438	0.736962697670679	0.966862335489626
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0004993	G protein-coupled serotonin receptor activity	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0005172	vascular endothelial growth factor receptor binding	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0008253	5'-nucleotidase activity	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0009982	pseudouridine synthase activity	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0030955	potassium ion binding	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0031432	titin binding	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0035325	Toll-like receptor binding	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0045159	myosin II binding	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0046974	histone H3K9 methyltransferase activity	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0071714	icosanoid transmembrane transporter activity	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0089720	caspase binding	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:1901338	catecholamine binding	2/3537	13/18639	0.153846153846154	0.810726169504796	0.737775012437632	0.966862335489626
GO:0005267	potassium channel activity	21/3537	124/18639	0.169354838709677	0.892452597882295	0.753015157080522	0.984096787282732
GO:0043425	bHLH transcription factor binding	5/3537	32/18639	0.15625	0.823393765903308	0.753136735580829	0.984096787282732
GO:0008157	protein phosphatase 1 binding	4/3537	26/18639	0.153846153846154	0.810726169504796	0.754875581214647	0.984096787282732
GO:0120014	phospholipid transfer activity	4/3537	26/18639	0.153846153846154	0.810726169504796	0.754875581214647	0.984096787282732
GO:0003954	NADH dehydrogenase activity	7/3537	44/18639	0.159090909090909	0.838364561647004	0.755270749916034	0.984096787282732
GO:0030547	signaling receptor inhibitor activity	7/3537	44/18639	0.159090909090909	0.838364561647004	0.755270749916034	0.984096787282732
GO:0016798	hydrolase activity, acting on glycosyl bonds	22/3537	130/18639	0.169230769230769	0.891798786455275	0.75796773574331	0.986428189265948
GO:0000339	RNA cap binding	3/3537	20/18639	0.15	0.790458015267176	0.76068928796962	0.986428189265948
GO:0010851	cyclase regulator activity	3/3537	20/18639	0.15	0.790458015267176	0.76068928796962	0.986428189265948
GO:0043024	ribosomal small subunit binding	3/3537	20/18639	0.15	0.790458015267176	0.76068928796962	0.986428189265948
GO:0140664	ATP-dependent DNA damage sensor activity	3/3537	20/18639	0.15	0.790458015267176	0.76068928796962	0.986428189265948
GO:0002020	protease binding	23/3537	136/18639	0.169117647058824	0.891202664271816	0.76276148214634	0.98817240632686
GO:0140223	general transcription initiation factor activity	11/3537	68/18639	0.161764705882353	0.852454722346954	0.767340637479837	0.992213060261749
GO:1990841	promoter-specific chromatin binding	11/3537	68/18639	0.161764705882353	0.852454722346954	0.767340637479837	0.992213060261749
GO:0031491	nucleosome binding	12/3537	74/18639	0.162162162162162	0.854549205694244	0.770878134920052	0.9958154979942
GO:0005344	oxygen carrier activity	2/3537	14/18639	0.142857142857143	0.75281715739731	0.775255921175764	0.9958154979942
GO:0008331	high voltage-gated calcium channel activity	2/3537	14/18639	0.142857142857143	0.75281715739731	0.775255921175764	0.9958154979942
GO:0015386	potassium:proton antiporter activity	2/3537	14/18639	0.142857142857143	0.75281715739731	0.775255921175764	0.9958154979942
GO:0016530	metallochaperone activity	2/3537	14/18639	0.142857142857143	0.75281715739731	0.775255921175764	0.9958154979942
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/3537	14/18639	0.142857142857143	0.75281715739731	0.775255921175764	0.9958154979942
GO:1901474	azole transmembrane transporter activity	2/3537	14/18639	0.142857142857143	0.75281715739731	0.775255921175764	0.9958154979942
GO:0042605	peptide antigen binding	7/3537	45/18639	0.155555555555556	0.819734238054849	0.776345212598085	0.995866687285796
GO:0005272	sodium channel activity	8/3537	51/18639	0.156862745098039	0.826622761063713	0.777494153944246	0.995866687285796
GO:0030544	Hsp70 protein binding	8/3537	51/18639	0.156862745098039	0.826622761063713	0.777494153944246	0.995866687285796
GO:0019003	GDP binding	12/3537	75/18639	0.16	0.843155216284987	0.78682390123102	1
GO:0005123	death receptor binding	3/3537	21/18639	0.142857142857143	0.75281715739731	0.790101603884073	1
GO:0005248	voltage-gated sodium channel activity	3/3537	21/18639	0.142857142857143	0.75281715739731	0.790101603884073	1
GO:0140312	cargo adaptor activity	3/3537	21/18639	0.142857142857143	0.75281715739731	0.790101603884073	1
GO:1904047	S-adenosyl-L-methionine binding	3/3537	21/18639	0.142857142857143	0.75281715739731	0.790101603884073	1
GO:0009055	electron transfer activity	19/3537	116/18639	0.163793103448276	0.863143809774502	0.795878471361464	1
GO:0030331	nuclear estrogen receptor binding	6/3537	40/18639	0.15	0.790458015267176	0.79720135054671	1
GO:0032451	demethylase activity	6/3537	40/18639	0.15	0.790458015267176	0.79720135054671	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	6/3537	40/18639	0.15	0.790458015267176	0.79720135054671	1
GO:0046873	metal ion transmembrane transporter activity	79/3537	450/18639	0.175555555555556	0.925128640090472	0.798259067242542	1
GO:0015020	glucuronosyltransferase activity	5/3537	34/18639	0.147058823529412	0.774958838497231	0.800121042755832	1
GO:0030332	cyclin binding	5/3537	34/18639	0.147058823529412	0.774958838497231	0.800121042755832	1
GO:0090482	vitamin transmembrane transporter activity	5/3537	34/18639	0.147058823529412	0.774958838497231	0.800121042755832	1
GO:0008083	growth factor activity	27/3537	162/18639	0.166666666666667	0.878286683630195	0.801825426443164	1
GO:0046625	sphingolipid binding	4/3537	28/18639	0.142857142857143	0.75281715739731	0.805858478374545	1
GO:0046966	nuclear thyroid hormone receptor binding	4/3537	28/18639	0.142857142857143	0.75281715739731	0.805858478374545	1
GO:0097718	disordered domain specific binding	4/3537	28/18639	0.142857142857143	0.75281715739731	0.805858478374545	1
GO:0004129	cytochrome-c oxidase activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0005523	tropomyosin binding	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0008252	nucleotidase activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0031386	protein tag activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0034483	heparan sulfate sulfotransferase activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0045504	dynein heavy chain binding	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0047372	monoacylglycerol lipase activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0051371	muscle alpha-actinin binding	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0061578	K63-linked deubiquitinase activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0141047	molecular tag activity	2/3537	15/18639	0.133333333333333	0.702629346904156	0.807958933173772	1
GO:0140097	catalytic activity, acting on DNA	58/3537	336/18639	0.172619047619048	0.909654065188416	0.809452746681883	1
GO:0070063	RNA polymerase binding	9/3537	59/18639	0.152542372881356	0.80385560874628	0.813339673905203	1
GO:0005539	glycosaminoglycan binding	41/3537	242/18639	0.169421487603306	0.89280381889681	0.813712127307276	1
GO:0004497	monooxygenase activity	17/3537	106/18639	0.160377358490566	0.845143789908301	0.814174211797048	1
GO:0015377	chloride:monoatomic cation symporter activity	3/3537	22/18639	0.136363636363636	0.718598195697432	0.816439338273333	1
GO:0033691	sialic acid binding	3/3537	22/18639	0.136363636363636	0.718598195697432	0.816439338273333	1
GO:0140517	protein-RNA adaptor activity	3/3537	22/18639	0.136363636363636	0.718598195697432	0.816439338273333	1
GO:0061650	ubiquitin-like protein conjugating enzyme activity	6/3537	41/18639	0.146341463414634	0.771178551480171	0.816658291142895	1
GO:0061134	peptidase regulator activity	38/3537	226/18639	0.168141592920354	0.886059132157896	0.820408125079141	1
GO:0061631	ubiquitin conjugating enzyme activity	5/3537	35/18639	0.142857142857143	0.75281715739731	0.820814712223944	1
GO:0004867	serine-type endopeptidase inhibitor activity	15/3537	95/18639	0.157894736842105	0.83206106870229	0.821731332779596	1
GO:0015085	calcium ion transmembrane transporter activity	24/3537	147/18639	0.163265306122449	0.860362465596926	0.822659389003647	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/3537	60/18639	0.15	0.790458015267176	0.82879683895537	1
GO:0017069	snRNA binding	8/3537	54/18639	0.148148148148148	0.780699274337951	0.829636684258663	1
GO:0038187	pattern recognition receptor activity	7/3537	48/18639	0.145833333333333	0.768500848176421	0.831444719826314	1
GO:0005262	calcium channel activity	21/3537	131/18639	0.16030534351145	0.844764291125226	0.835012896456869	1
GO:0005506	iron ion binding	25/3537	154/18639	0.162337662337662	0.855474042496943	0.835029927187034	1
GO:0005149	interleukin-1 receptor binding	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0015378	sodium:chloride symporter activity	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0015385	sodium:proton antiporter activity	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0017070	U6 snRNA binding	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0019841	retinol binding	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0030275	LRR domain binding	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/3537	16/18639	0.125	0.658715012722646	0.836347173464983	1
GO:0005212	structural constituent of eye lens	3/3537	23/18639	0.130434782608696	0.6873547958845	0.839911286093741	1
GO:0048019	receptor antagonist activity	4/3537	30/18639	0.133333333333333	0.702629346904156	0.84785079143379	1
GO:0051721	protein phosphatase 2A binding	4/3537	30/18639	0.133333333333333	0.702629346904156	0.84785079143379	1
GO:0051082	unfolded protein binding	19/3537	121/18639	0.15702479338843	0.827476710197043	0.850960281204143	1
GO:0005245	voltage-gated calcium channel activity	6/3537	43/18639	0.13953488372093	0.735309781643884	0.851119376855119	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	10/3537	68/18639	0.147058823529412	0.774958838497231	0.85547617454102	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	19/3537	122/18639	0.155737704918033	0.820694114211822	0.860489327275045	1
GO:0004622	lysophospholipase activity	3/3537	24/18639	0.125	0.658715012722646	0.860738454969542	1
GO:0005540	hyaluronic acid binding	3/3537	24/18639	0.125	0.658715012722646	0.860738454969542	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/3537	24/18639	0.125	0.658715012722646	0.860738454969542	1
GO:0019957	C-C chemokine binding	3/3537	24/18639	0.125	0.658715012722646	0.860738454969542	1
GO:0030552	cAMP binding	3/3537	24/18639	0.125	0.658715012722646	0.860738454969542	1
GO:0009881	photoreceptor activity	2/3537	17/18639	0.117647058823529	0.619967070797785	0.860880092658885	1
GO:0016018	cyclosporin A binding	2/3537	17/18639	0.117647058823529	0.619967070797785	0.860880092658885	1
GO:0045125	bioactive lipid receptor activity	2/3537	17/18639	0.117647058823529	0.619967070797785	0.860880092658885	1
GO:0070492	oligosaccharide binding	2/3537	17/18639	0.117647058823529	0.619967070797785	0.860880092658885	1
GO:0017147	Wnt-protein binding	4/3537	31/18639	0.129032258064516	0.679963884100796	0.865793988704414	1
GO:0001046	core promoter sequence-specific DNA binding	6/3537	44/18639	0.136363636363636	0.718598195697432	0.866253370582343	1
GO:0017171	serine hydrolase activity	32/3537	198/18639	0.161616161616162	0.851671935641401	0.866853376368409	1
GO:0005200	structural constituent of cytoskeleton	17/3537	112/18639	0.151785714285714	0.799868229734642	0.876740205088015	1
GO:0001094	TFIID-class transcription factor complex binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0003796	lysozyme activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0004090	carbonyl reductase (NADPH) activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0005131	growth hormone receptor binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0005337	nucleoside transmembrane transporter activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0005381	iron ion transmembrane transporter activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0008239	dipeptidyl-peptidase activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0015279	store-operated calcium channel activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0015643	toxic substance binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0019911	structural constituent of myelin sheath	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0031720	haptoglobin binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0031996	thioesterase binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0032052	bile acid binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0032356	oxidized DNA binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0032395	MHC class II receptor activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0035374	chondroitin sulfate binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0051880	G-quadruplex DNA binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0070739	protein-glutamic acid ligase activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0070740	tubulin-glutamic acid ligase activity	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0071723	lipopeptide binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0097177	mitochondrial ribosome binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:1990763	arrestin family protein binding	1/3537	10/18639	0.1	0.526972010178117	0.878136706008607	1
GO:0008236	serine-type peptidase activity	31/3537	194/18639	0.15979381443299	0.842068676057816	0.878978808856931	1
GO:0005537	D-mannose binding	3/3537	25/18639	0.12	0.63236641221374	0.879145577308766	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/3537	25/18639	0.12	0.63236641221374	0.879145577308766	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/3537	25/18639	0.12	0.63236641221374	0.879145577308766	1
GO:0017025	TBP-class protein binding	3/3537	25/18639	0.12	0.63236641221374	0.879145577308766	1
GO:0004536	DNA nuclease activity	9/3537	64/18639	0.140625	0.741054389312977	0.880872843567108	1
GO:0031369	translation initiation factor binding	4/3537	32/18639	0.125	0.658715012722646	0.881887882007784	1
GO:0000400	four-way junction DNA binding	2/3537	18/18639	0.111111111111111	0.585524455753463	0.881998187459165	1
GO:0003746	translation elongation factor activity	2/3537	18/18639	0.111111111111111	0.585524455753463	0.881998187459165	1
GO:0008409	5'-3' exonuclease activity	2/3537	18/18639	0.111111111111111	0.585524455753463	0.881998187459165	1
GO:0015373	monoatomic anion:sodium symporter activity	2/3537	18/18639	0.111111111111111	0.585524455753463	0.881998187459165	1
GO:0032393	MHC class I receptor activity	2/3537	18/18639	0.111111111111111	0.585524455753463	0.881998187459165	1
GO:0035615	clathrin adaptor activity	2/3537	18/18639	0.111111111111111	0.585524455753463	0.881998187459165	1
GO:0061980	regulatory RNA binding	8/3537	58/18639	0.137931034482759	0.726857945073265	0.883686103528217	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/3537	39/18639	0.128205128205128	0.675605141253996	0.886851600654269	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	20/3537	132/18639	0.151515151515152	0.798442439663814	0.894432991575484	1
GO:0051139	metal cation:proton antiporter activity	3/3537	26/18639	0.115384615384615	0.608044627128597	0.895354707234086	1
GO:0019956	chemokine binding	4/3537	33/18639	0.121212121212121	0.638753951731051	0.896274716634277	1
GO:0140662	ATP-dependent protein folding chaperone	5/3537	40/18639	0.125	0.658715012722646	0.899658779241063	1
GO:0003756	protein disulfide isomerase activity	2/3537	19/18639	0.105263157894737	0.55470737913486	0.900113649782937	1
GO:0008301	DNA binding, bending	2/3537	19/18639	0.105263157894737	0.55470737913486	0.900113649782937	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/3537	19/18639	0.105263157894737	0.55470737913486	0.900113649782937	1
GO:0008574	plus-end-directed microtubule motor activity	2/3537	19/18639	0.105263157894737	0.55470737913486	0.900113649782937	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/3537	19/18639	0.105263157894737	0.55470737913486	0.900113649782937	1
GO:0022821	solute:potassium antiporter activity	2/3537	19/18639	0.105263157894737	0.55470737913486	0.900113649782937	1
GO:0099589	serotonin receptor activity	2/3537	19/18639	0.105263157894737	0.55470737913486	0.900113649782937	1
GO:0001851	complement component C3b binding	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0008503	benzodiazepine receptor activity	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0008526	phosphatidylinositol transfer activity	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0019107	myristoyltransferase activity	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0019864	IgG binding	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0043522	leucine zipper domain binding	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3537	11/18639	0.0909090909090909	0.479065463798288	0.901274312474201	1
GO:0003925	G protein activity	7/3537	54/18639	0.12962962962963	0.683111865045707	0.90909516975869	1
GO:0005249	voltage-gated potassium channel activity	14/3537	98/18639	0.142857142857143	0.75281715739731	0.909920727853746	1
GO:0001530	lipopolysaccharide binding	5/3537	41/18639	0.121951219512195	0.642648792900143	0.911186624810253	1
GO:0004812	aminoacyl-tRNA ligase activity	5/3537	41/18639	0.121951219512195	0.642648792900143	0.911186624810253	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/3537	41/18639	0.121951219512195	0.642648792900143	0.911186624810253	1
GO:0000049	tRNA binding	11/3537	80/18639	0.1375	0.724586513994911	0.9141217508972	1
GO:0005525	GTP binding	62/3537	378/18639	0.164021164021164	0.864345625159875	0.914340146261454	1
GO:0140693	molecular condensate scaffold activity	6/3537	48/18639	0.125	0.658715012722646	0.914535017833752	1
GO:0030145	manganese ion binding	9/3537	68/18639	0.132352941176471	0.697462954647508	0.919175347239261	1
GO:0000340	RNA 7-methylguanosine cap binding	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0003720	telomerase activity	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0004859	phospholipase inhibitor activity	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0005078	MAP-kinase scaffold activity	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0005165	neurotrophin receptor binding	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0008504	monoamine transmembrane transporter activity	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0010853	cyclase activator activity	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0015132	prostaglandin transmembrane transporter activity	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0035197	siRNA binding	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/3537	12/18639	0.0833333333333333	0.439143341815098	0.920019897441925	1
GO:0015079	potassium ion transmembrane transporter activity	24/3537	160/18639	0.15	0.790458015267176	0.921014753211105	1
GO:0042056	chemoattractant activity	5/3537	42/18639	0.119047619047619	0.627347631164425	0.92153475781956	1
GO:0051879	Hsp90 protein binding	5/3537	42/18639	0.119047619047619	0.627347631164425	0.92153475781956	1
GO:0051393	alpha-actinin binding	3/3537	28/18639	0.107142857142857	0.564612868047982	0.922027197467048	1
GO:0051537	2 iron, 2 sulfur cluster binding	3/3537	28/18639	0.107142857142857	0.564612868047982	0.922027197467048	1
GO:0044183	protein folding chaperone	10/3537	75/18639	0.133333333333333	0.702629346904156	0.924032691861905	1
GO:0022843	voltage-gated monoatomic cation channel activity	21/3537	143/18639	0.146853146853147	0.77387497998185	0.926048100425666	1
GO:0019212	phosphatase inhibitor activity	7/3537	56/18639	0.125	0.658715012722646	0.92701674506158	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	7/3537	56/18639	0.125	0.658715012722646	0.92701674506158	1
GO:0070182	DNA polymerase binding	2/3537	21/18639	0.0952380952380952	0.50187810493154	0.928816155187962	1
GO:0005507	copper ion binding	8/3537	63/18639	0.126984126984127	0.669170806575387	0.930445817375531	1
GO:0003964	RNA-directed DNA polymerase activity	1/3537	13/18639	0.0769230769230769	0.405363084752398	0.935206971192282	1
GO:0019104	DNA N-glycosylase activity	1/3537	13/18639	0.0769230769230769	0.405363084752398	0.935206971192282	1
GO:0032396	inhibitory MHC class I receptor activity	1/3537	13/18639	0.0769230769230769	0.405363084752398	0.935206971192282	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/3537	13/18639	0.0769230769230769	0.405363084752398	0.935206971192282	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/3537	13/18639	0.0769230769230769	0.405363084752398	0.935206971192282	1
GO:0071837	HMG box domain binding	1/3537	13/18639	0.0769230769230769	0.405363084752398	0.935206971192282	1
GO:0140666	annealing activity	1/3537	13/18639	0.0769230769230769	0.405363084752398	0.935206971192282	1
GO:0030551	cyclic nucleotide binding	4/3537	37/18639	0.108108108108108	0.569699470462829	0.93949855956658	1
GO:0042805	actinin binding	4/3537	37/18639	0.108108108108108	0.569699470462829	0.93949855956658	1
GO:0008970	phospholipase A1 activity	2/3537	22/18639	0.0909090909090909	0.479065463798288	0.940053836879424	1
GO:0016881	acid-amino acid ligase activity	2/3537	22/18639	0.0909090909090909	0.479065463798288	0.940053836879424	1
GO:0015081	sodium ion transmembrane transporter activity	24/3537	164/18639	0.146341463414634	0.771178551480171	0.940142236573127	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	6/3537	52/18639	0.115384615384615	0.608044627128597	0.946873922718758	1
GO:0019001	guanyl nucleotide binding	64/3537	400/18639	0.16	0.843155216284987	0.947499997036527	1
GO:0032561	guanyl ribonucleotide binding	64/3537	400/18639	0.16	0.843155216284987	0.947499997036527	1
GO:0008494	translation activator activity	1/3537	14/18639	0.0714285714285714	0.376408578698655	0.94751089811663	1
GO:0019763	immunoglobulin receptor activity	1/3537	14/18639	0.0714285714285714	0.376408578698655	0.94751089811663	1
GO:0042813	Wnt receptor activity	1/3537	14/18639	0.0714285714285714	0.376408578698655	0.94751089811663	1
GO:0061783	peptidoglycan muralytic activity	1/3537	14/18639	0.0714285714285714	0.376408578698655	0.94751089811663	1
GO:1901612	cardiolipin binding	1/3537	14/18639	0.0714285714285714	0.376408578698655	0.94751089811663	1
GO:1990825	sequence-specific mRNA binding	1/3537	14/18639	0.0714285714285714	0.376408578698655	0.94751089811663	1
GO:0016493	C-C chemokine receptor activity	2/3537	23/18639	0.0869565217391304	0.458236530589667	0.949591222668537	1
GO:0008327	methyl-CpG binding	3/3537	31/18639	0.0967741935483871	0.509972913075597	0.950535122430814	1
GO:0047499	calcium-independent phospholipase A2 activity	3/3537	31/18639	0.0967741935483871	0.509972913075597	0.950535122430814	1
GO:0005244	voltage-gated monoatomic ion channel activity	25/3537	173/18639	0.144508670520231	0.761520245922135	0.951577448798156	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/3537	46/18639	0.108695652173913	0.572795663237084	0.95300464856016	1
GO:0016860	intramolecular oxidoreductase activity	6/3537	53/18639	0.113207547169811	0.596572086994095	0.953011658081273	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	6/3537	53/18639	0.113207547169811	0.596572086994095	0.953011658081273	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	78/3537	484/18639	0.161157024793388	0.849252413096965	0.956203133762027	1
GO:0004089	carbonate dehydratase activity	1/3537	15/18639	0.0666666666666667	0.351314673452078	0.957478895612548	1
GO:0008020	G protein-coupled photoreceptor activity	1/3537	15/18639	0.0666666666666667	0.351314673452078	0.957478895612548	1
GO:0015250	water channel activity	1/3537	15/18639	0.0666666666666667	0.351314673452078	0.957478895612548	1
GO:0042809	nuclear vitamin D receptor binding	1/3537	15/18639	0.0666666666666667	0.351314673452078	0.957478895612548	1
GO:0050700	CARD domain binding	1/3537	15/18639	0.0666666666666667	0.351314673452078	0.957478895612548	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/3537	15/18639	0.0666666666666667	0.351314673452078	0.957478895612548	1
GO:0030515	snoRNA binding	3/3537	32/18639	0.09375	0.494036259541985	0.957636561095265	1
GO:0022832	voltage-gated channel activity	25/3537	175/18639	0.142857142857143	0.75281715739731	0.958134748837916	1
GO:0099095	ligand-gated monoatomic anion channel activity	5/3537	47/18639	0.106382978723404	0.560608521466082	0.958820829271748	1
GO:0004252	serine-type endopeptidase activity	25/3537	176/18639	0.142045454545455	0.748539787184825	0.961115569407661	1
GO:0046906	tetrapyrrole binding	21/3537	152/18639	0.138157894736842	0.728053435114504	0.962760063507222	1
GO:0098960	postsynaptic neurotransmitter receptor activity	8/3537	69/18639	0.115942028985507	0.610982040786223	0.964231247637886	1
GO:0001848	complement binding	2/3537	25/18639	0.08	0.421577608142494	0.964496848717509	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/3537	25/18639	0.08	0.421577608142494	0.964496848717509	1
GO:0008296	3'-5'-DNA exonuclease activity	1/3537	16/18639	0.0625	0.329357506361323	0.965554343755719	1
GO:0140828	metal cation:monoatomic cation antiporter activity	4/3537	41/18639	0.0975609756097561	0.514119034320114	0.965660040521287	1
GO:0008528	G protein-coupled peptide receptor activity	16/3537	122/18639	0.131147540983607	0.691110833020481	0.966708063633474	1
GO:0001216	DNA-binding transcription activator activity	78/3537	491/18639	0.158859470468432	0.837144944885807	0.968393280041166	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/3537	34/18639	0.0882352941176471	0.464975303098339	0.969064120288779	1
GO:0019825	oxygen binding	3/3537	34/18639	0.0882352941176471	0.464975303098339	0.969064120288779	1
GO:0020037	heme binding	19/3537	142/18639	0.133802816901408	0.705103393900297	0.96962305554508	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/3537	26/18639	0.0769230769230769	0.405363084752398	0.970258693841127	1
GO:0004529	DNA exonuclease activity	2/3537	26/18639	0.0769230769230769	0.405363084752398	0.970258693841127	1
GO:0004950	chemokine receptor activity	2/3537	26/18639	0.0769230769230769	0.405363084752398	0.970258693841127	1
GO:0005112	Notch binding	2/3537	26/18639	0.0769230769230769	0.405363084752398	0.970258693841127	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/3537	26/18639	0.0769230769230769	0.405363084752398	0.970258693841127	1
GO:0019865	immunoglobulin binding	2/3537	26/18639	0.0769230769230769	0.405363084752398	0.970258693841127	1
GO:0016504	peptidase activator activity	6/3537	57/18639	0.105263157894737	0.55470737913486	0.971650985553437	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/3537	17/18639	0.0588235294117647	0.309983535398892	0.972096484449271	1
GO:0016805	dipeptidase activity	1/3537	17/18639	0.0588235294117647	0.309983535398892	0.972096484449271	1
GO:0031489	myosin V binding	1/3537	17/18639	0.0588235294117647	0.309983535398892	0.972096484449271	1
GO:0070402	NADPH binding	1/3537	17/18639	0.0588235294117647	0.309983535398892	0.972096484449271	1
GO:0001217	DNA-binding transcription repressor activity	41/3537	278/18639	0.147482014388489	0.777188935874201	0.97343992426112	1
GO:0004623	phospholipase A2 activity	3/3537	35/18639	0.0857142857142857	0.451690294438386	0.973618296753141	1
GO:0005104	fibroblast growth factor receptor binding	2/3537	27/18639	0.0740740740740741	0.390349637168976	0.975112945428989	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	39/3537	268/18639	0.145522388059701	0.766862253617409	0.976651367441263	1
GO:0005372	water transmembrane transporter activity	1/3537	18/18639	0.0555555555555556	0.292762227876732	0.977396384272219	1
GO:1901611	phosphatidylglycerol binding	1/3537	18/18639	0.0555555555555556	0.292762227876732	0.977396384272219	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	3/3537	36/18639	0.0833333333333333	0.439143341815098	0.977530945672121	1
GO:0005242	inward rectifier potassium channel activity	2/3537	28/18639	0.0714285714285714	0.376408578698655	0.979196464502985	1
GO:0030280	structural constituent of skin epidermis	3/3537	37/18639	0.0810810810810811	0.427274602847122	0.98088674444614	1
GO:0001653	peptide receptor activity	16/3537	128/18639	0.125	0.658715012722646	0.980908738775867	1
GO:0031490	chromatin DNA binding	16/3537	128/18639	0.125	0.658715012722646	0.980908738775867	1
GO:0042834	peptidoglycan binding	1/3537	19/18639	0.0526315789473684	0.27735368956743	0.981689869521623	1
GO:0004864	protein phosphatase inhibitor activity	5/3537	53/18639	0.0943396226415094	0.497143405828412	0.981898685684739	1
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/3537	29/18639	0.0689655172413793	0.363428972536632	0.982626868544537	1
GO:0097472	cyclin-dependent protein kinase activity	2/3537	29/18639	0.0689655172413793	0.363428972536632	0.982626868544537	1
GO:0106222	lncRNA binding	2/3537	29/18639	0.0689655172413793	0.363428972536632	0.982626868544537	1
GO:0099094	ligand-gated monoatomic cation channel activity	17/3537	136/18639	0.125	0.658715012722646	0.983456268590951	1
GO:0030594	neurotransmitter receptor activity	11/3537	97/18639	0.11340206185567	0.597597124944256	0.984766766632734	1
GO:0001614	purinergic nucleotide receptor activity	1/3537	20/18639	0.05	0.263486005089059	0.985168007625921	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/3537	20/18639	0.05	0.263486005089059	0.985168007625921	1
GO:0015464	acetylcholine receptor activity	1/3537	20/18639	0.05	0.263486005089059	0.985168007625921	1
GO:0016502	nucleotide receptor activity	1/3537	20/18639	0.05	0.263486005089059	0.985168007625921	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/3537	30/18639	0.0666666666666667	0.351314673452078	0.98550490432957	1
GO:0005216	monoatomic ion channel activity	68/3537	448/18639	0.151785714285714	0.799868229734642	0.985522312411977	1
GO:0022824	transmitter-gated monoatomic ion channel activity	6/3537	63/18639	0.0952380952380952	0.50187810493154	0.987214448880473	1
GO:0022835	transmitter-gated channel activity	6/3537	63/18639	0.0952380952380952	0.50187810493154	0.987214448880473	1
GO:0008188	neuropeptide receptor activity	4/3537	48/18639	0.0833333333333333	0.439143341815098	0.987914921587845	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/3537	21/18639	0.0476190476190476	0.25093905246577	0.987985600247819	1
GO:0001846	opsonin binding	1/3537	21/18639	0.0476190476190476	0.25093905246577	0.987985600247819	1
GO:0019200	carbohydrate kinase activity	1/3537	21/18639	0.0476190476190476	0.25093905246577	0.987985600247819	1
GO:0051428	peptide hormone receptor binding	1/3537	21/18639	0.0476190476190476	0.25093905246577	0.987985600247819	1
GO:0061791	GTPase motor activity	3/3537	40/18639	0.075	0.395229007633588	0.988315002291595	1
GO:1990606	membrane scission GTPase motor activity	3/3537	40/18639	0.075	0.395229007633588	0.988315002291595	1
GO:0047498	calcium-dependent phospholipase A2 activity	2/3537	32/18639	0.0625	0.329357506361323	0.989935283581421	1
GO:0008227	G protein-coupled amine receptor activity	3/3537	41/18639	0.0731707317073171	0.385589275740086	0.99010355190504	1
GO:0005243	gap junction channel activity	1/3537	22/18639	0.0454545454545455	0.239532731899144	0.990268065170123	1
GO:0031683	G-protein beta/gamma-subunit complex binding	1/3537	22/18639	0.0454545454545455	0.239532731899144	0.990268065170123	1
GO:0019843	rRNA binding	6/3537	65/18639	0.0923076923076923	0.486435701702877	0.990283860124131	1
GO:0042923	neuropeptide binding	2/3537	33/18639	0.0606060606060606	0.319376975865525	0.991623189261425	1
GO:0031492	nucleosomal DNA binding	3/3537	42/18639	0.0714285714285714	0.376408578698655	0.991626532273007	1
GO:0017134	fibroblast growth factor binding	1/3537	23/18639	0.0434782608695652	0.229118265294833	0.992117012556559	1
GO:0051427	hormone receptor binding	2/3537	34/18639	0.0588235294117647	0.309983535398892	0.993033131072215	1
GO:0005261	monoatomic cation channel activity	48/3537	341/18639	0.140762463343109	0.741778782655414	0.993344764736207	1
GO:0015276	ligand-gated monoatomic ion channel activity	23/3537	186/18639	0.123655913978495	0.651632055596596	0.994086224821985	1
GO:0022834	ligand-gated channel activity	23/3537	188/18639	0.122340425531915	0.644699799685994	0.995087891545995	1
GO:0004033	aldo-keto reductase (NADPH) activity	2/3537	36/18639	0.0555555555555556	0.292762227876732	0.995190896052054	1
GO:0022829	wide pore channel activity	2/3537	37/18639	0.0540540540540541	0.284849735231415	0.996008276143821	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	6/3537	73/18639	0.0821917808219178	0.433127679598452	0.996884876977063	1
GO:0022836	gated channel activity	42/3537	318/18639	0.132075471698113	0.696000768159777	0.997657647451043	1
GO:0008135	translation factor activity, RNA binding	7/3537	83/18639	0.0843373493975904	0.444434225451424	0.997708784448908	1
GO:0180051	translation factor activity	7/3537	84/18639	0.0833333333333333	0.439143341815098	0.998012128906023	1
GO:0005184	neuropeptide hormone activity	1/3537	31/18639	0.032258064516129	0.169990971025199	0.998539750940572	1
GO:0005179	hormone activity	13/3537	132/18639	0.0984848484848485	0.518987585781479	0.998671785303193	1
GO:0051059	NF-kappaB binding	1/3537	32/18639	0.03125	0.164678753180662	0.998817314403771	1
GO:0160041	neuropeptide activity	1/3537	32/18639	0.03125	0.164678753180662	0.998817314403771	1
GO:0046982	protein heterodimerization activity	47/3537	369/18639	0.127371273712737	0.671210961473482	0.999513092270439	1
GO:0003743	translation initiation factor activity	2/3537	51/18639	0.0392156862745098	0.206655690265928	0.999720970654902	1
GO:0071855	neuropeptide receptor binding	1/3537	40/18639	0.025	0.131743002544529	0.999781117504094	1
GO:0003823	antigen binding	15/3537	174/18639	0.0862068965517241	0.454286215670791	0.999957323236209	1
GO:0003730	mRNA 3'-UTR binding	22/3537	262/18639	0.083969465648855	0.442495581065595	0.999999536199736	1
GO:0003735	structural constituent of ribosome	11/3537	175/18639	0.0628571428571429	0.331239549254816	0.999999651059828	1
GO:0030527	structural constituent of chromatin	1/3537	98/18639	0.0102040816326531	0.0537726540998079	0.999999998957868	1
GO:0004984	olfactory receptor activity	1/3537	419/18639	0.00238663484486874	0.0125768976176162	1	1
GO:0030371	translation repressor activity	6/3537	329/18639	0.0182370820668693	0.096104317965614	1	1
GO:0045182	translation regulator activity	9/3537	356/18639	0.0252808988764045	0.133223261000086	1	1