ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 146/3523 495/18639 0.294949494949495 1.56047789848528 5.28464778207475e-09 7.01801225459527e-06 GO:0030695 GTPase regulator activity 143/3523 489/18639 0.292433537832311 1.54716682136147 1.38713549037324e-08 7.08053408645752e-06 GO:0060589 nucleoside-triphosphatase regulator activity 143/3523 490/18639 0.291836734693878 1.54400933805256 1.59951824242263e-08 7.08053408645752e-06 GO:0004674 protein serine/threonine kinase activity 129/3523 433/18639 0.297921478060046 1.57620165471507 2.13932543684911e-08 7.10256045033903e-06 GO:0106310 protein serine kinase activity 109/3523 361/18639 0.301939058171745 1.59745731060549 1.23419972109088e-07 3.27803445921737e-05 GO:0005085 guanyl-nucleotide exchange factor activity 72/3523 230/18639 0.31304347826087 1.65620703698676 3.983773046672e-06 0.000881741767663402 GO:0031267 small GTPase binding 84/3523 283/18639 0.296819787985866 1.57037298559993 6.89884712331166e-06 0.00114535243541114 GO:0005096 GTPase activator activity 81/3523 271/18639 0.298892988929889 1.58134158974289 7.49596583695459e-06 0.00114535243541114 GO:0003779 actin binding 121/3523 443/18639 0.27313769751693 1.44507906443885 7.76217764962372e-06 0.00114535243541114 GO:0016779 nucleotidyltransferase activity 47/3523 136/18639 0.345588235294118 1.82839032575846 1.08247963825007e-05 0.00143753295959609 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 98/3523 349/18639 0.28080229226361 1.48562983976765 1.65586551574711e-05 0.00167618501669832 GO:0051020 GTPase binding 89/3523 315/18639 0.282539682539683 1.49482178338267 3.08032062735127e-05 0.00167618501669832 GO:0035403 histone H3T6 kinase activity 73/3523 247/18639 0.295546558704453 1.56363676062796 3.12786672617455e-05 0.00167618501669832 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 72/3523 243/18639 0.296296296296296 1.56760336834138 3.22133658729655e-05 0.00167618501669832 GO:0140297 DNA-binding transcription factor binding 128/3523 488/18639 0.262295081967213 1.38771445722023 3.5182715042386e-05 0.00167618501669832 GO:0035173 histone kinase activity 99/3523 360/18639 0.275 1.45493187624184 3.75235708315271e-05 0.00167618501669832 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 14/3523 25/18639 0.56 2.9627703661652 3.90750443319056e-05 0.00167618501669832 GO:0004676 3-phosphoinositide-dependent protein kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0004711 ribosomal protein S6 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0035175 histone H3S10 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0035979 histone H2AXS139 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0044022 histone H3S28 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0044023 histone H4S1 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0044024 histone H2AS1 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0044025 histone H2BS14 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0072354 histone H3T3 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0072371 histone H2AS121 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0072518 Rho-dependent protein serine/threonine kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0140823 histone H2BS36 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0140855 histone H3S57 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0140995 histone H2A kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0140997 histone H4 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0140998 histone H2B kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:1990244 histone H2AT120 kinase activity 72/3523 245/18639 0.293877551020408 1.55480660615083 4.32691748459064e-05 0.00167618501669832 GO:0140996 histone H3 kinase activity 98/3523 357/18639 0.274509803921569 1.45233841478686 4.41765629400913e-05 0.00167618501669832 GO:0004677 DNA-dependent protein kinase activity 72/3523 246/18639 0.292682926829268 1.54848625409331 5.00220616910832e-05 0.0017953864304259 GO:0140857 histone H3T45 kinase activity 72/3523 246/18639 0.292682926829268 1.54848625409331 5.00220616910832e-05 0.0017953864304259 GO:0141003 histone H2AX kinase activity 97/3523 354/18639 0.274011299435028 1.44970099635807 5.19888075864125e-05 0.00181687201249357 GO:0035402 histone H3T11 kinase activity 72/3523 247/18639 0.291497975708502 1.54221707897552 5.77336296848674e-05 0.00196590410824369 GO:0016791 phosphatase activity 78/3523 273/18639 0.285714285714286 1.51161753375776 6.1482122195929e-05 0.00204120645690484 GO:0004679 AMP-activated protein kinase activity 72/3523 248/18639 0.290322580645161 1.53599846172159 6.65254273589419e-05 0.00215477481787012 GO:0003714 transcription corepressor activity 61/3523 204/18639 0.299019607843137 1.58201148753569 9.33771670681743e-05 0.00295249709206037 GO:0043560 insulin receptor substrate binding 9/3523 13/18639 0.692307692307692 3.66276556256687 0.000103998757877783 0.0031562840300201 GO:0042393 histone binding 71/3523 247/18639 0.287449392712551 1.52079739732309 0.000104575675693437 0.0031562840300201 GO:0042578 phosphoric ester hydrolase activity 97/3523 363/18639 0.267217630853994 1.41375799644837 0.000143936175938444 0.00422990970163524 GO:0016922 nuclear receptor binding 44/3523 137/18639 0.321167883211679 1.69919051239923 0.000146517956532546 0.00422990970163524 GO:0035591 signaling adaptor activity 41/3523 129/18639 0.317829457364341 1.68152803173828 0.000310134025727055 0.0087499197253649 GO:0042054 histone methyltransferase activity 25/3523 67/18639 0.373134328358209 1.97412737617617 0.000316262158748129 0.0087499197253649 GO:0003713 transcription coactivator activity 71/3523 256/18639 0.27734375 1.46733186382345 0.000337122252817798 0.00913670105595992 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 50/3523 167/18639 0.29940119760479 1.58403034974615 0.000368874286358794 0.00979730104568957 GO:0005049 nuclear export signal receptor activity 8/3523 12/18639 0.666666666666667 3.5271075787681 0.000385625065462118 0.0100413742536018 GO:0017124 SH3 domain binding 37/3523 115/18639 0.321739130434783 1.70221278801417 0.000456687418615037 0.0116630940753994 GO:0000287 magnesium ion binding 64/3523 230/18639 0.278260869565217 1.47218403287712 0.000584358183670723 0.0146420314700891 GO:0004721 phosphoprotein phosphatase activity 51/3523 175/18639 0.291428571428571 1.54184988443291 0.000650542980522 0.0159985384839484 GO:0019787 ubiquitin-like protein transferase activity 119/3523 479/18639 0.248434237995825 1.31438142549082 0.000673599955441989 0.0162643771059448 GO:0001727 lipid kinase activity 17/3523 41/18639 0.414634146341463 2.19368885996552 0.000700962381514954 0.0166228221902118 GO:0046975 histone H3K36 methyltransferase activity 8/3523 13/18639 0.615384615384615 3.25579161117055 0.000836227157597053 0.0194826257068226 GO:0140030 modification-dependent protein binding 50/3523 173/18639 0.289017341040462 1.52909288096883 0.000895669195035766 0.0205077360518534 GO:0046332 SMAD binding 27/3523 79/18639 0.341772151898734 1.80820072076086 0.000924613897790776 0.0208116484112907 GO:0005024 transforming growth factor beta receptor activity 9/3523 16/18639 0.5625 2.97599701958558 0.000958563769419656 0.0212162114298217 GO:0004842 ubiquitin-protein transferase activity 111/3523 449/18639 0.247216035634744 1.30793632932046 0.00120039295284383 0.0261331449406002 GO:0050998 nitric-oxide synthase binding 7/3523 11/18639 0.636363636363636 3.36678450700591 0.00138028817342067 0.0294422534500209 GO:0052742 phosphatidylinositol kinase activity 12/3523 26/18639 0.461538461538462 2.44184370837791 0.00139673340915009 0.0294422534500209 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 11/3523 23/18639 0.478260869565217 2.53031630650755 0.00153943154136247 0.0319432044832712 GO:0016755 aminoacyltransferase activity 120/3523 496/18639 0.241935483870968 1.27999871810133 0.00178861689873693 0.036511650230452 GO:0016887 ATP hydrolysis activity 103/3523 417/18639 0.247002398081535 1.30680604537091 0.00181458502651343 0.036511650230452 GO:0051015 actin filament binding 57/3523 209/18639 0.272727272727273 1.44290764585968 0.00187180307097933 0.0371008131083665 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 12/3523 27/18639 0.444444444444444 2.35140505251206 0.00208550920206613 0.0407287679462327 GO:0052866 phosphatidylinositol phosphate phosphatase activity 14/3523 34/18639 0.411764705882353 2.17850762218029 0.00220854447696172 0.0425064792087705 GO:0035035 histone acetyltransferase binding 11/3523 24/18639 0.458333333333333 2.42488646040307 0.00236059986619152 0.0447839517471762 GO:0016763 pentosyltransferase activity 18/3523 49/18639 0.36734693877551 1.94350825768854 0.00257161286141017 0.0457898712804948 GO:0051010 microtubule plus-end binding 10/3523 21/18639 0.476190476190476 2.51936255626292 0.00262097752029796 0.0457898712804948 GO:0019902 phosphatase binding 52/3523 190/18639 0.273684210526316 1.4479704797048 0.00265701884515166 0.0457898712804948 GO:0051018 protein kinase A binding 19/3523 53/18639 0.358490566037736 1.89665218858284 0.00273458472127482 0.0457898712804948 GO:0005025 transforming growth factor beta receptor activity, type I 7/3523 12/18639 0.583333333333333 3.08621913142208 0.00277281652456265 0.0457898712804948 GO:0005026 transforming growth factor beta receptor activity, type II 7/3523 12/18639 0.583333333333333 3.08621913142208 0.00277281652456265 0.0457898712804948 GO:0016361 activin receptor activity, type I 7/3523 12/18639 0.583333333333333 3.08621913142208 0.00277281652456265 0.0457898712804948 GO:0016362 activin receptor activity, type II 7/3523 12/18639 0.583333333333333 3.08621913142208 0.00277281652456265 0.0457898712804948 GO:0017002 activin receptor activity 7/3523 12/18639 0.583333333333333 3.08621913142208 0.00277281652456265 0.0457898712804948 GO:0035259 nuclear glucocorticoid receptor binding 7/3523 12/18639 0.583333333333333 3.08621913142208 0.00277281652456265 0.0457898712804948 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 9/3523 18/18639 0.5 2.64533068407607 0.00282738663027152 0.0457898712804948 GO:0004706 JUN kinase kinase kinase activity 9/3523 18/18639 0.5 2.64533068407607 0.00282738663027152 0.0457898712804948 GO:0015026 coreceptor activity 21/3523 61/18639 0.344262295081967 1.82137522510156 0.00296524609788854 0.0474439375662167 GO:0045499 chemorepellent activity 12/3523 28/18639 0.428571428571429 2.26742630063663 0.00302855833608679 0.0478800651228959 GO:0016279 protein-lysine N-methyltransferase activity 23/3523 69/18639 0.333333333333333 1.76355378938405 0.00308789298183787 0.0482437868221259 GO:0000030 mannosyltransferase activity 11/3523 25/18639 0.44 2.32789100198694 0.00350272996494994 0.0528593794710628 GO:0004709 MAP kinase kinase kinase activity 11/3523 25/18639 0.44 2.32789100198694 0.00350272996494994 0.0528593794710628 GO:0017056 structural constituent of nuclear pore 11/3523 25/18639 0.44 2.32789100198694 0.00350272996494994 0.0528593794710628 GO:0140789 histone phosphatase activity 39/3523 136/18639 0.286764705882353 1.51717495116128 0.0035960789738437 0.0536583469355555 GO:0048156 tau protein binding 16/3523 43/18639 0.372093023255814 1.96861818349847 0.00376535428618448 0.0553186121509382 GO:0016278 lysine N-methyltransferase activity 23/3523 70/18639 0.328571428571429 1.73836016382142 0.00379065791094531 0.0553186121509382 GO:0031625 ubiquitin protein ligase binding 76/3523 302/18639 0.251655629139073 1.33142471516412 0.00406507780026537 0.0586785143342654 GO:0008276 protein methyltransferase activity 29/3523 95/18639 0.305263157894737 1.61504399659381 0.00426239929604411 0.0608652286574901 GO:0031593 polyubiquitin modification-dependent protein binding 20/3523 59/18639 0.338983050847458 1.793444531577 0.00450589873008922 0.0632575862392965 GO:0004386 helicase activity 43/3523 155/18639 0.27741935483871 1.46773186342285 0.00452520383488943 0.0632575862392965 GO:0044389 ubiquitin-like protein ligase binding 80/3523 322/18639 0.248447204968944 1.31445002935457 0.00467086426785818 0.0646136223720381 GO:0071889 14-3-3 protein binding 13/3523 33/18639 0.393939393939394 2.08419993290842 0.00495876380879378 0.065711619992763 GO:0070123 transforming growth factor beta receptor activity, type III 7/3523 13/18639 0.538461538461538 2.84881765977423 0.00503217078602251 0.065711619992763 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 7/3523 13/18639 0.538461538461538 2.84881765977423 0.00503217078602251 0.065711619992763 GO:0140852 histone ubiquitin ligase activity 7/3523 13/18639 0.538461538461538 2.84881765977423 0.00503217078602251 0.065711619992763 GO:0005160 transforming growth factor beta receptor binding 11/3523 26/18639 0.423076923076923 2.23835673267975 0.00504712743920318 0.065711619992763 GO:0070412 R-SMAD binding 11/3523 26/18639 0.423076923076923 2.23835673267975 0.00504712743920318 0.065711619992763 GO:0030159 signaling receptor complex adaptor activity 18/3523 52/18639 0.346153846153846 1.83138278128343 0.00535639318327664 0.0690610693921493 GO:0045296 cadherin binding 82/3523 334/18639 0.245508982035928 1.29890488679184 0.00586136703505435 0.0724368148276931 GO:0019903 protein phosphatase binding 40/3523 144/18639 0.277777777777778 1.46962815782004 0.00587524036163329 0.0724368148276931 GO:0003887 DNA-directed DNA polymerase activity 10/3523 23/18639 0.434782608695652 2.3002875513705 0.00589094578417986 0.0724368148276931 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 10/3523 23/18639 0.434782608695652 2.3002875513705 0.00589094578417986 0.0724368148276931 GO:0005158 insulin receptor binding 10/3523 23/18639 0.434782608695652 2.3002875513705 0.00589094578417986 0.0724368148276931 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 27/3523 89/18639 0.303370786516854 1.60503210045065 0.00623305683039406 0.0752144907544809 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 27/3523 89/18639 0.303370786516854 1.60503210045065 0.00623305683039406 0.0752144907544809 GO:0140303 intramembrane lipid transporter activity 16/3523 45/18639 0.355555555555556 1.88112404200965 0.00628675336878568 0.0752144907544809 GO:0000149 SNARE binding 31/3523 106/18639 0.292452830188679 1.547268890686 0.00644847672922842 0.0764605097894227 GO:0052745 inositol phosphate phosphatase activity 9/3523 20/18639 0.45 2.38079761566846 0.00679297643447044 0.0796649266286486 GO:0004725 protein tyrosine phosphatase activity 29/3523 98/18639 0.295918367346939 1.5656038742491 0.00689869470052303 0.0796649266286486 GO:0008170 N-methyltransferase activity 29/3523 98/18639 0.295918367346939 1.5656038742491 0.00689869470052303 0.0796649266286486 GO:0140793 histone H2AXY142 phosphatase activity 27/3523 90/18639 0.3 1.58719841044564 0.00733426203346779 0.0839646550038382 GO:0008168 methyltransferase activity 53/3523 204/18639 0.259803921568627 1.37453457113757 0.00764679281551265 0.0867943663162461 GO:0015605 organophosphate ester transmembrane transporter activity 17/3523 50/18639 0.34 1.79882486517173 0.00819114395329689 0.0921850777116803 GO:0008408 3'-5' exonuclease activity 19/3523 58/18639 0.327586206896552 1.73314768956708 0.00836721824570185 0.0933589854091771 GO:0098821 BMP receptor activity 7/3523 14/18639 0.5 2.64533068407607 0.00843605289841962 0.0933589854091771 GO:0048185 activin binding 6/3523 11/18639 0.545454545454545 2.88581529171935 0.00875589753511324 0.0957471717995564 GO:0005154 epidermal growth factor receptor binding 13/3523 35/18639 0.371428571428571 1.96510279388508 0.00879605042134479 0.0957471717995564 GO:0140938 histone H3 methyltransferase activity 16/3523 47/18639 0.340425531914894 1.80107621043477 0.0100187759272951 0.108170198629658 GO:0004879 nuclear receptor activity 19/3523 59/18639 0.322033898305085 1.70377230499815 0.0102013450156178 0.10925311436081 GO:0016757 glycosyltransferase activity 66/3523 267/18639 0.247191011235955 1.30780393370053 0.0106220285601946 0.112006035211759 GO:0140142 nucleocytoplasmic carrier activity 12/3523 32/18639 0.375 1.98399801305705 0.0107001786827818 0.112006035211759 GO:0004527 exonuclease activity 25/3523 84/18639 0.297619047619048 1.57460159766433 0.0107114205360643 0.112006035211759 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 8/3523 18/18639 0.444444444444444 2.35140505251206 0.0115760010076361 0.120101010454224 GO:0061659 ubiquitin-like protein ligase activity 88/3523 372/18639 0.236559139784946 1.25155430214352 0.0122739275353106 0.125237579793157 GO:0098531 ligand-modulated transcription factor activity 19/3523 60/18639 0.316666666666667 1.67537609991485 0.0123429428730201 0.125237579793157 GO:0009378 four-way junction helicase activity 16/3523 48/18639 0.333333333333333 1.76355378938405 0.0124483136541391 0.125237579793157 GO:0043138 3'-5' DNA helicase activity 16/3523 48/18639 0.333333333333333 1.76355378938405 0.0124483136541391 0.125237579793157 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 7/3523 15/18639 0.466666666666667 2.46897530513767 0.0132683318763184 0.131495109938439 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 7/3523 15/18639 0.466666666666667 2.46897530513767 0.0132683318763184 0.131495109938439 GO:0140097 catalytic activity, acting on DNA 80/3523 336/18639 0.238095238095238 1.25968127813146 0.013965912431284 0.135926217891777 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 9/3523 22/18639 0.409090909090909 2.16436146878951 0.0140225089240764 0.135926217891777 GO:0070034 telomerase RNA binding 9/3523 22/18639 0.409090909090909 2.16436146878951 0.0140225089240764 0.135926217891777 GO:0016741 transferase activity, transferring one-carbon groups 54/3523 215/18639 0.251162790697674 1.32881727386147 0.014213417228425 0.136778391879337 GO:0035497 cAMP response element binding 6/3523 12/18639 0.5 2.64533068407607 0.0147389785456638 0.136876667892598 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 6/3523 12/18639 0.5 2.64533068407607 0.0147389785456638 0.136876667892598 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 6/3523 12/18639 0.5 2.64533068407607 0.0147389785456638 0.136876667892598 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 6/3523 12/18639 0.5 2.64533068407607 0.0147389785456638 0.136876667892598 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 6/3523 12/18639 0.5 2.64533068407607 0.0147389785456638 0.136876667892598 GO:0015932 nucleobase-containing compound transmembrane transporter activity 18/3523 57/18639 0.315789473684211 1.67073516889015 0.0150728918178026 0.13900555787529 GO:0043548 phosphatidylinositol 3-kinase binding 10/3523 26/18639 0.384615384615385 2.03486975698159 0.0158351042881598 0.145027713756388 GO:0061630 ubiquitin protein ligase activity 83/3523 353/18639 0.235127478753541 1.24397986843237 0.0169751742212924 0.151975758956617 GO:0005543 phospholipid binding 113/3523 497/18639 0.227364185110664 1.20290691066638 0.0170964682928121 0.151975758956617 GO:0031624 ubiquitin conjugating enzyme binding 11/3523 30/18639 0.366666666666667 1.93990916832245 0.0171178804692487 0.151975758956617 GO:0032452 histone demethylase activity 11/3523 30/18639 0.366666666666667 1.93990916832245 0.0171178804692487 0.151975758956617 GO:0019207 kinase regulator activity 69/3523 287/18639 0.240418118466899 1.27197085157665 0.017165936629136 0.151975758956617 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 13/3523 38/18639 0.342105263157895 1.809963099631 0.01849068761777 0.162620087128467 GO:0003725 double-stranded RNA binding 22/3523 75/18639 0.293333333333333 1.55192733465796 0.0189365244600285 0.165387486193929 GO:0035091 phosphatidylinositol binding 68/3523 284/18639 0.23943661971831 1.2667780740646 0.0195050103366691 0.165387486193929 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 7/3523 16/18639 0.4375 2.31466434856656 0.0198016643861707 0.165387486193929 GO:0005159 insulin-like growth factor receptor binding 7/3523 16/18639 0.4375 2.31466434856656 0.0198016643861707 0.165387486193929 GO:0034450 ubiquitin-ubiquitin ligase activity 7/3523 16/18639 0.4375 2.31466434856656 0.0198016643861707 0.165387486193929 GO:0070411 I-SMAD binding 7/3523 16/18639 0.4375 2.31466434856656 0.0198016643861707 0.165387486193929 GO:0140327 flippase activity 7/3523 16/18639 0.4375 2.31466434856656 0.0198016643861707 0.165387486193929 GO:0140328 floppase activity 7/3523 16/18639 0.4375 2.31466434856656 0.0198016643861707 0.165387486193929 GO:0051117 ATPase binding 24/3523 84/18639 0.285714285714286 1.51161753375776 0.0202711884728857 0.168250864324951 GO:0008013 beta-catenin binding 29/3523 106/18639 0.273584905660377 1.44744509128691 0.0209619559942754 0.17201091955649 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 10/3523 27/18639 0.37037037037037 1.95950421042672 0.0209832597651742 0.17201091955649 GO:0140457 protein demethylase activity 11/3523 31/18639 0.354838709677419 1.87733145321528 0.022107194616754 0.180112603994168 GO:0000175 3'-5'-RNA exonuclease activity 12/3523 35/18639 0.342857142857143 1.81394104050931 0.022761817410311 0.180132259486818 GO:0034061 DNA polymerase activity 12/3523 35/18639 0.342857142857143 1.81394104050931 0.022761817410311 0.180132259486818 GO:0061749 forked DNA-dependent helicase activity 15/3523 47/18639 0.319148936170213 1.6885089472826 0.0228950488513212 0.180132259486818 GO:1990518 single-stranded 3'-5' DNA helicase activity 15/3523 47/18639 0.319148936170213 1.6885089472826 0.0228950488513212 0.180132259486818 GO:0000217 DNA secondary structure binding 13/3523 39/18639 0.333333333333333 1.76355378938405 0.0230575085431652 0.180132259486818 GO:0005338 nucleotide-sugar transmembrane transporter activity 6/3523 13/18639 0.461538461538462 2.44184370837791 0.0230590994824992 0.180132259486818 GO:0140333 glycerophospholipid flippase activity 6/3523 13/18639 0.461538461538462 2.44184370837791 0.0230590994824992 0.180132259486818 GO:0005516 calmodulin binding 51/3523 207/18639 0.246376811594203 1.30349627910995 0.0237601877688325 0.184523563491284 GO:0003697 single-stranded DNA binding 32/3523 121/18639 0.264462809917355 1.39918317174272 0.0255906484623279 0.197578319109141 GO:0016303 1-phosphatidylinositol-3-kinase activity 5/3523 10/18639 0.5 2.64533068407607 0.0260362995814003 0.197578319109141 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 5/3523 10/18639 0.5 2.64533068407607 0.0260362995814003 0.197578319109141 GO:0051864 histone H3K36 demethylase activity 5/3523 10/18639 0.5 2.64533068407607 0.0260362995814003 0.197578319109141 GO:0019887 protein kinase regulator activity 61/3523 255/18639 0.23921568627451 1.26560919002855 0.0262215787831987 0.197853730818681 GO:0046966 nuclear thyroid hormone receptor binding 10/3523 28/18639 0.357142857142857 1.88952191719719 0.0272479276848587 0.19945882645835 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 10/3523 28/18639 0.357142857142857 1.88952191719719 0.0272479276848587 0.19945882645835 GO:0141052 histone H3 demethylase activity 10/3523 28/18639 0.357142857142857 1.88952191719719 0.0272479276848587 0.19945882645835 GO:0032266 phosphatidylinositol-3-phosphate binding 15/3523 48/18639 0.3125 1.65333167754754 0.0276435648500404 0.19945882645835 GO:0036121 double-stranded DNA helicase activity 15/3523 48/18639 0.3125 1.65333167754754 0.0276435648500404 0.19945882645835 GO:0002039 p53 binding 20/3523 69/18639 0.289855072463768 1.533525034247 0.0277195246716823 0.19945882645835 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 7/3523 17/18639 0.411764705882353 2.17850762218029 0.0282814198907694 0.19945882645835 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 7/3523 17/18639 0.411764705882353 2.17850762218029 0.0282814198907694 0.19945882645835 GO:0019198 transmembrane receptor protein phosphatase activity 7/3523 17/18639 0.411764705882353 2.17850762218029 0.0282814198907694 0.19945882645835 GO:0046965 nuclear retinoid X receptor binding 7/3523 17/18639 0.411764705882353 2.17850762218029 0.0282814198907694 0.19945882645835 GO:0004532 RNA exonuclease activity 13/3523 40/18639 0.325 1.71946494464945 0.0284092006634446 0.19945882645835 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 13/3523 40/18639 0.325 1.71946494464945 0.0284092006634446 0.19945882645835 GO:0044390 ubiquitin-like protein conjugating enzyme binding 12/3523 36/18639 0.333333333333333 1.76355378938405 0.0284268711934886 0.19945882645835 GO:0031072 heat shock protein binding 34/3523 131/18639 0.259541984732824 1.37314875203949 0.0285370308938904 0.19945882645835 GO:0019199 transmembrane receptor protein kinase activity 22/3523 78/18639 0.282051282051282 1.4922378217865 0.0293405056761628 0.204001002816462 GO:0044325 transmembrane transporter binding 35/3523 136/18639 0.257352941176471 1.36156726386268 0.02996272176355 0.207242158864554 GO:0031491 nucleosome binding 21/3523 74/18639 0.283783783783784 1.50140390177291 0.0307122668585027 0.211325856933117 GO:0140296 general transcription initiation factor binding 16/3523 53/18639 0.30188679245283 1.59718079038555 0.0321133497786306 0.218700146184726 GO:1901505 carbohydrate derivative transmembrane transporter activity 16/3523 53/18639 0.30188679245283 1.59718079038555 0.0321133497786306 0.218700146184726 GO:0017025 TBP-class protein binding 9/3523 25/18639 0.36 1.90463809253477 0.0336647144649519 0.225935192552511 GO:0008174 mRNA methyltransferase activity 6/3523 14/18639 0.428571428571429 2.26742630063663 0.0340263844205589 0.225935192552511 GO:0032454 histone H3K9 demethylase activity 6/3523 14/18639 0.428571428571429 2.26742630063663 0.0340263844205589 0.225935192552511 GO:0034236 protein kinase A catalytic subunit binding 6/3523 14/18639 0.428571428571429 2.26742630063663 0.0340263844205589 0.225935192552511 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 6/3523 14/18639 0.428571428571429 2.26742630063663 0.0340263844205589 0.225935192552511 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 10/3523 29/18639 0.344827586206897 1.82436598901798 0.0347374168523829 0.229508903382908 GO:0140416 transcription regulator inhibitor activity 11/3523 33/18639 0.333333333333333 1.76355378938405 0.0351329537107217 0.230973081820983 GO:0008237 metallopeptidase activity 45/3523 184/18639 0.244565217391304 1.2939117476459 0.0359330370015237 0.235069325803071 GO:0004143 ATP-dependent diacylglycerol kinase activity 5/3523 11/18639 0.454545454545455 2.40484607643279 0.0404366346199729 0.256494817577019 GO:0005114 type II transforming growth factor beta receptor binding 5/3523 11/18639 0.454545454545455 2.40484607643279 0.0404366346199729 0.256494817577019 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 5/3523 11/18639 0.454545454545455 2.40484607643279 0.0404366346199729 0.256494817577019 GO:0034056 estrogen response element binding 5/3523 11/18639 0.454545454545455 2.40484607643279 0.0404366346199729 0.256494817577019 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 5/3523 11/18639 0.454545454545455 2.40484607643279 0.0404366346199729 0.256494817577019 GO:0045294 alpha-catenin binding 5/3523 11/18639 0.454545454545455 2.40484607643279 0.0404366346199729 0.256494817577019 GO:0030276 clathrin binding 14/3523 46/18639 0.304347826086957 1.61020128595935 0.0405601744662454 0.256494817577019 GO:0050321 tau-protein kinase activity 8/3523 22/18639 0.363636363636364 1.92387686114623 0.0417093164587049 0.261273454043208 GO:0140035 ubiquitin-like protein reader activity 8/3523 22/18639 0.363636363636364 1.92387686114623 0.0417093164587049 0.261273454043208 GO:0008198 ferrous iron binding 9/3523 26/18639 0.346153846153846 1.83138278128343 0.0431039198526654 0.267734545085025 GO:0015215 nucleotide transmembrane transporter activity 10/3523 30/18639 0.333333333333333 1.76355378938405 0.0435471850439498 0.267734545085025 GO:0035925 mRNA 3'-UTR AU-rich region binding 10/3523 30/18639 0.333333333333333 1.76355378938405 0.0435471850439498 0.267734545085025 GO:0070566 adenylyltransferase activity 10/3523 30/18639 0.333333333333333 1.76355378938405 0.0435471850439498 0.267734545085025 GO:0008094 ATP-dependent activity, acting on DNA 50/3523 210/18639 0.238095238095238 1.25968127813146 0.0439492022337472 0.268961016435098 GO:0043539 protein serine/threonine kinase activator activity 20/3523 73/18639 0.273972602739726 1.44949626524716 0.0484227613774138 0.294979023436722 GO:0015631 tubulin binding 86/3523 385/18639 0.223376623376623 1.18181007184697 0.0491545095119579 0.296111742217007 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 17/3523 60/18639 0.283333333333333 1.49902072097644 0.0491841522278612 0.296111742217007 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 22/3523 82/18639 0.268292682926829 1.41944573291887 0.0492776317996675 0.296111742217007 GO:0016776 phosphotransferase activity, phosphate group as acceptor 12/3523 39/18639 0.307692307692308 1.62789580558528 0.0514088253865708 0.30601427599051 GO:0005346 purine ribonucleotide transmembrane transporter activity 7/3523 19/18639 0.368421052631579 1.94919103037184 0.0518472982664644 0.30601427599051 GO:0042800 histone H3K4 methyltransferase activity 7/3523 19/18639 0.368421052631579 1.94919103037184 0.0518472982664644 0.30601427599051 GO:0140036 ubiquitin-modified protein reader activity 7/3523 19/18639 0.368421052631579 1.94919103037184 0.0518472982664644 0.30601427599051 GO:0043015 gamma-tubulin binding 11/3523 35/18639 0.314285714285714 1.66277928713353 0.0527711171205144 0.308722658749089 GO:0061631 ubiquitin conjugating enzyme activity 11/3523 35/18639 0.314285714285714 1.66277928713353 0.0527711171205144 0.308722658749089 GO:0070273 phosphatidylinositol-4-phosphate binding 10/3523 31/18639 0.32258064516129 1.70666495746843 0.0537567042949955 0.311741935824254 GO:0072349 modified amino acid transmembrane transporter activity 10/3523 31/18639 0.32258064516129 1.70666495746843 0.0537567042949955 0.311741935824254 GO:0001671 ATPase activator activity 9/3523 27/18639 0.333333333333333 1.76355378938405 0.0541642498964109 0.312739668967103 GO:0140098 catalytic activity, acting on RNA 86/3523 387/18639 0.222222222222222 1.17570252625603 0.0546439502671862 0.314143575562006 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 22/3523 83/18639 0.265060240963855 1.40234397710057 0.0555014329683774 0.317697857681057 GO:0001221 transcription coregulator binding 29/3523 115/18639 0.252173913043478 1.33416677979489 0.0567404273350981 0.323396083695323 GO:0004000 adenosine deaminase activity 5/3523 12/18639 0.416666666666667 2.20444223673006 0.0587921032444793 0.32750196474877 GO:0070679 inositol 1,4,5 trisphosphate binding 5/3523 12/18639 0.416666666666667 2.20444223673006 0.0587921032444793 0.32750196474877 GO:1990817 poly(A) RNA polymerase activity 5/3523 12/18639 0.416666666666667 2.20444223673006 0.0587921032444793 0.32750196474877 GO:0001223 transcription coactivator binding 13/3523 44/18639 0.295454545454545 1.56314994968132 0.0588976405409294 0.32750196474877 GO:0043014 alpha-tubulin binding 13/3523 44/18639 0.295454545454545 1.56314994968132 0.0588976405409294 0.32750196474877 GO:0032182 ubiquitin-like protein binding 30/3523 120/18639 0.25 1.32266534203804 0.0589404891377682 0.32750196474877 GO:0019209 kinase activator activity 36/3523 148/18639 0.243243243243243 1.28691763009106 0.0595664695615148 0.329601131573715 GO:0030331 nuclear estrogen receptor binding 12/3523 40/18639 0.3 1.58719841044564 0.0612658074107678 0.335204252040206 GO:0032451 demethylase activity 12/3523 40/18639 0.3 1.58719841044564 0.0612658074107678 0.335204252040206 GO:0008235 metalloexopeptidase activity 18/3523 66/18639 0.272727272727273 1.44290764585968 0.0613363202151882 0.335204252040206 GO:0140658 ATP-dependent chromatin remodeler activity 38/3523 158/18639 0.240506329113924 1.27243754423912 0.0626854727114923 0.341173392462548 GO:0019955 cytokine binding 35/3523 144/18639 0.243055555555556 1.28592463809253 0.0630770877431923 0.341903561318202 GO:0001217 DNA-binding transcription repressor activity 63/3523 278/18639 0.226618705035971 1.19896282803448 0.0645655279866434 0.343703075191618 GO:0003688 DNA replication origin binding 6/3523 16/18639 0.375 1.98399801305705 0.0647031391550485 0.343703075191618 GO:0004707 MAP kinase activity 6/3523 16/18639 0.375 1.98399801305705 0.0647031391550485 0.343703075191618 GO:0022858 alanine transmembrane transporter activity 6/3523 16/18639 0.375 1.98399801305705 0.0647031391550485 0.343703075191618 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 6/3523 16/18639 0.375 1.98399801305705 0.0647031391550485 0.343703075191618 GO:0060590 ATPase regulator activity 14/3523 49/18639 0.285714285714286 1.51161753375776 0.0658095883114821 0.348187781982662 GO:0051393 alpha-actinin binding 9/3523 28/18639 0.321428571428571 1.70056972547747 0.0669140867334619 0.350961902433178 GO:0140939 histone H4 methyltransferase activity 7/3523 20/18639 0.35 1.85173147885325 0.0671826683904513 0.350961902433178 GO:0004722 protein serine/threonine phosphatase activity 26/3523 103/18639 0.252427184466019 1.33550675312578 0.0676194711165246 0.350961902433178 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 8/3523 24/18639 0.333333333333333 1.76355378938405 0.0676553064931428 0.350961902433178 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 8/3523 24/18639 0.333333333333333 1.76355378938405 0.0676553064931428 0.350961902433178 GO:0005319 lipid transporter activity 42/3523 178/18639 0.235955056179775 1.24835830035051 0.0682027176404153 0.351988296596194 GO:0017116 single-stranded DNA helicase activity 16/3523 58/18639 0.275862068965517 1.45949279121438 0.0683832684652245 0.351988296596194 GO:0008173 RNA methyltransferase activity 18/3523 67/18639 0.26865671641791 1.42137171084684 0.0696173326637596 0.356956825395648 GO:0140463 chromatin-protein adaptor activity 15/3523 54/18639 0.277777777777778 1.46962815782004 0.0721723467789756 0.359052999050982 GO:0042169 SH2 domain binding 12/3523 41/18639 0.292682926829268 1.54848625409331 0.0722951096744106 0.359052999050982 GO:0061650 ubiquitin-like protein conjugating enzyme activity 12/3523 41/18639 0.292682926829268 1.54848625409331 0.0722951096744106 0.359052999050982 GO:0019210 kinase inhibitor activity 23/3523 90/18639 0.255555555555556 1.35205790519444 0.0729627660422644 0.359052999050982 GO:0019783 ubiquitin-like protein peptidase activity 31/3523 127/18639 0.244094488188976 1.29142127884029 0.0729929162120307 0.359052999050982 GO:0001618 virus receptor activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0033192 calmodulin-dependent protein phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0140791 histone H2AXS140 phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:1990439 MAP kinase serine/threonine phosphatase activity 21/3523 81/18639 0.259259259259259 1.3716529472987 0.0738113469434624 0.359052999050982 GO:0005548 phospholipid transporter activity 18/3523 68/18639 0.264705882352941 1.40046918568733 0.0786196921034492 0.379661640412293 GO:0030145 manganese ion binding 18/3523 68/18639 0.264705882352941 1.40046918568733 0.0786196921034492 0.379661640412293 GO:1901981 phosphatidylinositol phosphate binding 43/3523 185/18639 0.232432432432432 1.2297212909759 0.0800785143647789 0.384777646816784 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 13/3523 46/18639 0.282608695652174 1.49518690839082 0.0802585904881395 0.384777646816784 GO:0099604 ligand-gated calcium channel activity 9/3523 29/18639 0.310344827586207 1.64192939011618 0.0813935881799475 0.388815414039462 GO:0033549 MAP kinase phosphatase activity 21/3523 82/18639 0.25609756097561 1.35492547233165 0.0822573800257523 0.390135002407854 GO:0140272 exogenous protein binding 21/3523 82/18639 0.25609756097561 1.35492547233165 0.0822573800257523 0.390135002407854 GO:0042974 nuclear retinoic acid receptor binding 8/3523 25/18639 0.32 1.69301163780869 0.0836508792122916 0.391729148727639 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 60/3523 268/18639 0.223880597014925 1.1844764257057 0.0842810507073505 0.391729148727639 GO:0004659 prenyltransferase activity 6/3523 17/18639 0.352941176470588 1.86729224758311 0.0845695314810189 0.391729148727639 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 6/3523 17/18639 0.352941176470588 1.86729224758311 0.0845695314810189 0.391729148727639 GO:0032183 SUMO binding 6/3523 17/18639 0.352941176470588 1.86729224758311 0.0845695314810189 0.391729148727639 GO:0004222 metalloendopeptidase activity 27/3523 110/18639 0.245454545454545 1.29861688127371 0.0846310035663014 0.391729148727639 GO:0008373 sialyltransferase activity 7/3523 21/18639 0.333333333333333 1.76355378938405 0.0849533093626206 0.391729148727639 GO:0009931 calcium-dependent protein serine/threonine kinase activity 7/3523 21/18639 0.333333333333333 1.76355378938405 0.0849533093626206 0.391729148727639 GO:0101005 deubiquitinase activity 28/3523 115/18639 0.243478260869565 1.28816102876748 0.0871339982569435 0.400394289568239 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 16/3523 60/18639 0.266666666666667 1.41084303150724 0.088511078956712 0.405319699498323 GO:0042887 amide transmembrane transporter activity 11/3523 38/18639 0.289473684210526 1.5315072381493 0.0888885012101336 0.405649242635936 GO:0030295 protein kinase activator activity 33/3523 139/18639 0.237410071942446 1.25605629603612 0.0903834266200051 0.411058871751256 GO:0003678 DNA helicase activity 19/3523 74/18639 0.256756756756757 1.35841305398501 0.092918462622222 0.413405348079342 GO:0008175 tRNA methyltransferase activity 10/3523 34/18639 0.294117647058824 1.55607687298592 0.0932892242612593 0.413405348079342 GO:0004540 RNA nuclease activity 29/3523 121/18639 0.239669421487603 1.26800974939184 0.0973056828375328 0.413405348079342 GO:0001968 fibronectin binding 9/3523 30/18639 0.3 1.58719841044564 0.0976134752382324 0.413405348079342 GO:0051721 protein phosphatase 2A binding 9/3523 30/18639 0.3 1.58719841044564 0.0976134752382324 0.413405348079342 GO:0051219 phosphoprotein binding 23/3523 93/18639 0.247311827956989 1.30844313405913 0.0983340180942593 0.413405348079342 GO:0019905 syntaxin binding 16/3523 61/18639 0.262295081967213 1.38771445722023 0.0998545516164241 0.413405348079342 GO:0004860 protein kinase inhibitor activity 21/3523 84/18639 0.25 1.32266534203804 0.101006069119658 0.413405348079342 GO:0017018 myosin phosphatase activity 21/3523 84/18639 0.25 1.32266534203804 0.101006069119658 0.413405348079342 GO:0004112 cyclic-nucleotide phosphodiesterase activity 8/3523 26/18639 0.307692307692308 1.62789580558528 0.101671750038792 0.413405348079342 GO:0015216 purine nucleotide transmembrane transporter activity 8/3523 26/18639 0.307692307692308 1.62789580558528 0.101671750038792 0.413405348079342 GO:0034237 protein kinase A regulatory subunit binding 8/3523 26/18639 0.307692307692308 1.62789580558528 0.101671750038792 0.413405348079342 GO:0070006 metalloaminopeptidase activity 8/3523 26/18639 0.307692307692308 1.62789580558528 0.101671750038792 0.413405348079342 GO:0003680 minor groove of adenine-thymine-rich DNA binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0004955 prostaglandin receptor activity 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0005522 profilin binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0015279 store-operated calcium channel activity 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0016427 tRNA (cytidine) methyltransferase activity 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0016783 sulfurtransferase activity 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0030957 Tat protein binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0031419 cobalamin binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0035374 chondroitin sulfate binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0045322 unmethylated CpG binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0070097 delta-catenin binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0099122 RNA polymerase II C-terminal domain binding 4/3523 10/18639 0.4 2.11626454726086 0.102269275265847 0.413405348079342 GO:0044183 protein folding chaperone 19/3523 75/18639 0.253333333333333 1.34030087993188 0.103360348169765 0.413405348079342 GO:0032931 histone H3K56 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0043992 histone H3K9 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0043993 histone H3K18 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0043994 histone H3K23 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0043999 histone H2AK5 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0044012 histone H2AK9 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0044014 histone H2BK5 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0044015 histone H2BK12 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0044016 histone H3K4 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0044017 histone H3K27 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0044018 histone H3K36 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0140908 histone H3K122 acetyltransferase activity 7/3523 22/18639 0.318181818181818 1.68339225350295 0.105133839384448 0.413405348079342 GO:0016879 ligase activity, forming carbon-nitrogen bonds 13/3523 48/18639 0.270833333333333 1.43288745387454 0.105985319459856 0.413405348079342 GO:0004843 cysteine-type deubiquitinase activity 26/3523 108/18639 0.240740740740741 1.27367773677737 0.107121132576006 0.413405348079342 GO:0005347 ATP transmembrane transporter activity 5/3523 14/18639 0.357142857142857 1.88952191719719 0.107291256248583 0.413405348079342 GO:0005545 1-phosphatidylinositol binding 5/3523 14/18639 0.357142857142857 1.88952191719719 0.107291256248583 0.413405348079342 GO:0019992 diacylglycerol binding 5/3523 14/18639 0.357142857142857 1.88952191719719 0.107291256248583 0.413405348079342 GO:0042043 neurexin family protein binding 5/3523 14/18639 0.357142857142857 1.88952191719719 0.107291256248583 0.413405348079342 GO:0046030 inositol trisphosphate phosphatase activity 5/3523 14/18639 0.357142857142857 1.88952191719719 0.107291256248583 0.413405348079342 GO:0070742 C2H2 zinc finger domain binding 5/3523 14/18639 0.357142857142857 1.88952191719719 0.107291256248583 0.413405348079342 GO:0000400 four-way junction DNA binding 6/3523 18/18639 0.333333333333333 1.76355378938405 0.107398226722419 0.413405348079342 GO:0017075 syntaxin-1 binding 6/3523 18/18639 0.333333333333333 1.76355378938405 0.107398226722419 0.413405348079342 GO:0017128 phospholipid scramblase activity 6/3523 18/18639 0.333333333333333 1.76355378938405 0.107398226722419 0.413405348079342 GO:0030228 lipoprotein particle receptor activity 6/3523 18/18639 0.333333333333333 1.76355378938405 0.107398226722419 0.413405348079342 GO:0070064 proline-rich region binding 6/3523 18/18639 0.333333333333333 1.76355378938405 0.107398226722419 0.413405348079342 GO:0004518 nuclease activity 47/3523 209/18639 0.22488038277512 1.18976595360359 0.108490666213349 0.41640348188245 GO:0140566 histone reader activity 10/3523 35/18639 0.285714285714286 1.51161753375776 0.109496467117557 0.419052761764023 GO:0005178 integrin binding 37/3523 161/18639 0.229813664596273 1.21586627715298 0.111573954526933 0.425776470148754 GO:0005246 calcium channel regulator activity 14/3523 53/18639 0.264150943396226 1.39753319158736 0.113105496023713 0.430384237018598 GO:0098631 cell adhesion mediator activity 19/3523 76/18639 0.25 1.32266534203804 0.114506340720854 0.433231967171779 GO:0140034 methylation-dependent protein binding 19/3523 76/18639 0.25 1.32266534203804 0.114506340720854 0.433231967171779 GO:0016878 acid-thiol ligase activity 9/3523 31/18639 0.290322580645161 1.53599846172159 0.115554881533193 0.435957053057045 GO:0031490 chromatin DNA binding 30/3523 128/18639 0.234375 1.23999875816066 0.116303278929027 0.437537547925631 GO:0016874 ligase activity 38/3523 167/18639 0.227544910179641 1.20386306580707 0.120640128574964 0.452570877817943 GO:0043130 ubiquitin binding 24/3523 100/18639 0.24 1.26975872835651 0.12104337527155 0.452804513691881 GO:0003774 cytoskeletal motor activity 35/3523 153/18639 0.228758169934641 1.21028201232239 0.124786772973596 0.464192813750521 GO:0061775 cohesin loader activity 35/3523 153/18639 0.228758169934641 1.21028201232239 0.124786772973596 0.464192813750521 GO:0005484 SNAP receptor activity 10/3523 36/18639 0.277777777777778 1.46962815782004 0.127194113959539 0.469551177668903 GO:0000295 adenine nucleotide transmembrane transporter activity 7/3523 23/18639 0.304347826086957 1.61020128595935 0.127641547544032 0.469551177668903 GO:0044013 histone H2B acetyltransferase activity 7/3523 23/18639 0.304347826086957 1.61020128595935 0.127641547544032 0.469551177668903 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 7/3523 23/18639 0.304347826086957 1.61020128595935 0.127641547544032 0.469551177668903 GO:0004715 non-membrane spanning protein tyrosine kinase activity 12/3523 45/18639 0.266666666666667 1.41084303150724 0.128455101547524 0.469940426598105 GO:0051539 4 iron, 4 sulfur cluster binding 12/3523 45/18639 0.266666666666667 1.41084303150724 0.128455101547524 0.469940426598105 GO:1990841 promoter-specific chromatin binding 17/3523 68/18639 0.25 1.32266534203804 0.130199668265596 0.470968398373417 GO:0008574 plus-end-directed microtubule motor activity 6/3523 19/18639 0.315789473684211 1.67073516889015 0.133037116779014 0.470968398373417 GO:0046624 sphingolipid transporter activity 6/3523 19/18639 0.315789473684211 1.67073516889015 0.133037116779014 0.470968398373417 GO:1990380 K48-linked deubiquitinase activity 6/3523 19/18639 0.315789473684211 1.67073516889015 0.133037116779014 0.470968398373417 GO:0045309 protein phosphorylated amino acid binding 15/3523 59/18639 0.254237288135593 1.34508339868275 0.133568885088011 0.470968398373417 GO:0070063 RNA polymerase binding 15/3523 59/18639 0.254237288135593 1.34508339868275 0.133568885088011 0.470968398373417 GO:0070717 poly-purine tract binding 9/3523 32/18639 0.28125 1.48799850979279 0.135170183004977 0.470968398373417 GO:0005041 low-density lipoprotein particle receptor activity 5/3523 15/18639 0.333333333333333 1.76355378938405 0.137004341314514 0.470968398373417 GO:0005523 tropomyosin binding 5/3523 15/18639 0.333333333333333 1.76355378938405 0.137004341314514 0.470968398373417 GO:0015556 C4-dicarboxylate transmembrane transporter activity 5/3523 15/18639 0.333333333333333 1.76355378938405 0.137004341314514 0.470968398373417 GO:0031005 filamin binding 5/3523 15/18639 0.333333333333333 1.76355378938405 0.137004341314514 0.470968398373417 GO:0033130 acetylcholine receptor binding 5/3523 15/18639 0.333333333333333 1.76355378938405 0.137004341314514 0.470968398373417 GO:0051371 muscle alpha-actinin binding 5/3523 15/18639 0.333333333333333 1.76355378938405 0.137004341314514 0.470968398373417 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 11/3523 41/18639 0.268292682926829 1.41944573291887 0.137047979960238 0.470968398373417 GO:0016877 ligase activity, forming carbon-sulfur bonds 11/3523 41/18639 0.268292682926829 1.41944573291887 0.137047979960238 0.470968398373417 GO:0043178 alcohol binding 22/3523 92/18639 0.239130434782609 1.26515815325377 0.137076732091244 0.470968398373417 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0002162 dystroglycan binding 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0004954 prostanoid receptor activity 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0005225 volume-sensitive anion channel activity 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0005536 D-glucose binding 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0035252 UDP-xylosyltransferase activity 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0042285 xylosyltransferase activity 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0140031 phosphorylation-dependent protein binding 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0180030 inositol phosphate kinase activity 4/3523 11/18639 0.363636363636364 1.92387686114623 0.137602212777775 0.470968398373417 GO:0098632 cell-cell adhesion mediator activity 14/3523 55/18639 0.254545454545455 1.34671380280236 0.142738625535443 0.487292788460331 GO:0099106 ion channel regulator activity 36/3523 160/18639 0.225 1.19039880783423 0.14358145595844 0.488913265417456 GO:0005262 calcium channel activity 30/3523 131/18639 0.229007633587786 1.21160184003484 0.144678556879563 0.491389062752071 GO:0030291 protein serine/threonine kinase inhibitor activity 12/3523 46/18639 0.260869565217391 1.3801725308223 0.145465634862601 0.492801946677384 GO:0042805 actinin binding 10/3523 37/18639 0.27027027027027 1.42990847787896 0.146334932884479 0.49448547295315 GO:0140104 molecular carrier activity 54/3523 249/18639 0.216867469879518 1.14737234490046 0.147399681432134 0.49681923081694 GO:0035064 methylated histone binding 18/3523 74/18639 0.243243243243243 1.28691763009106 0.148226195914699 0.497040474167088 GO:0001098 basal transcription machinery binding 15/3523 60/18639 0.25 1.32266534203804 0.148588153798444 0.497040474167088 GO:0001099 basal RNA polymerase II transcription machinery binding 15/3523 60/18639 0.25 1.32266534203804 0.148588153798444 0.497040474167088 GO:1990782 protein tyrosine kinase binding 27/3523 117/18639 0.230769230769231 1.22092185418896 0.14963804234367 0.497183207600868 GO:0000510 H3-H4 histone complex chaperone activity 34/3523 151/18639 0.225165562913907 1.19127474514684 0.150502748083998 0.497183207600868 GO:0140584 chromatin extrusion motor activity 34/3523 151/18639 0.225165562913907 1.19127474514684 0.150502748083998 0.497183207600868 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 34/3523 151/18639 0.225165562913907 1.19127474514684 0.150502748083998 0.497183207600868 GO:0140849 ATP-dependent H2AZ histone chaperone activity 34/3523 151/18639 0.225165562913907 1.19127474514684 0.150502748083998 0.497183207600868 GO:0001091 RNA polymerase II general transcription initiation factor binding 7/3523 24/18639 0.291666666666667 1.54310956571104 0.152341764447339 0.499516964107335 GO:0030215 semaphorin receptor binding 7/3523 24/18639 0.291666666666667 1.54310956571104 0.152341764447339 0.499516964107335 GO:0043998 histone H2A acetyltransferase activity 7/3523 24/18639 0.291666666666667 1.54310956571104 0.152341764447339 0.499516964107335 GO:0030544 Hsp70 protein binding 13/3523 51/18639 0.254901960784314 1.3485999565878 0.152713770653297 0.499516964107335 GO:0042826 histone deacetylase binding 29/3523 127/18639 0.228346456692913 1.20810377697962 0.15333925467084 0.500330541039005 GO:0038024 cargo receptor activity 16/3523 65/18639 0.246153846153846 1.30231664446822 0.153750469647426 0.500442705126916 GO:0019894 kinesin binding 11/3523 42/18639 0.261904761904762 1.38564940594461 0.155685918504535 0.504270487253713 GO:0031492 nucleosomal DNA binding 11/3523 42/18639 0.261904761904762 1.38564940594461 0.155685918504535 0.504270487253713 GO:0015085 calcium ion transmembrane transporter activity 33/3523 147/18639 0.224489795918367 1.18769949080966 0.159123149742284 0.514149739313269 GO:0015616 DNA translocase activity 34/3523 152/18639 0.223684210526316 1.18343741129719 0.160292348882625 0.51479298075472 GO:0140674 ATP-dependent histone chaperone activity 34/3523 152/18639 0.223684210526316 1.18343741129719 0.160292348882625 0.51479298075472 GO:0000339 RNA cap binding 6/3523 20/18639 0.3 1.58719841044564 0.161260451802684 0.51479298075472 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6/3523 20/18639 0.3 1.58719841044564 0.161260451802684 0.51479298075472 GO:0016004 phospholipase activator activity 6/3523 20/18639 0.3 1.58719841044564 0.161260451802684 0.51479298075472 GO:0001784 phosphotyrosine residue binding 12/3523 47/18639 0.25531914893617 1.35080715782608 0.163600619179383 0.521011084580866 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 29/3523 128/18639 0.2265625 1.19866546622197 0.164188176857835 0.521309873129875 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 15/3523 61/18639 0.245901639344262 1.30098230364397 0.16447954581432 0.521309873129875 GO:0008234 cysteine-type peptidase activity 41/3523 187/18639 0.219251336898396 1.15998457804405 0.166191481035922 0.523899154893014 GO:0005109 frizzled binding 10/3523 38/18639 0.263157894736842 1.39227930740846 0.166851515625316 0.523899154893014 GO:0042162 telomeric DNA binding 10/3523 38/18639 0.263157894736842 1.39227930740846 0.166851515625316 0.523899154893014 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 8/3523 29/18639 0.275862068965517 1.45949279121438 0.167269007285119 0.523899154893014 GO:0097472 cyclin-dependent protein kinase activity 8/3523 29/18639 0.275862068965517 1.45949279121438 0.167269007285119 0.523899154893014 GO:0008296 3'-5'-DNA exonuclease activity 5/3523 16/18639 0.3125 1.65333167754754 0.169868524114271 0.52954319254402 GO:0016722 oxidoreductase activity, acting on metal ions 5/3523 16/18639 0.3125 1.65333167754754 0.169868524114271 0.52954319254402 GO:0051087 protein-folding chaperone binding 30/3523 134/18639 0.223880597014925 1.1844764257057 0.176771236478248 0.534991310031899 GO:0000340 RNA 7-methylguanosine cap binding 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0005165 neurotrophin receptor binding 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0008603 cAMP-dependent protein kinase regulator activity 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0016208 AMP binding 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0016423 tRNA (guanine) methyltransferase activity 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0017166 vinculin binding 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0035014 phosphatidylinositol 3-kinase regulator activity 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0045295 gamma-catenin binding 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0097677 STAT family protein binding 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 4/3523 12/18639 0.333333333333333 1.76355378938405 0.177007267544423 0.534991310031899 GO:0017022 myosin binding 18/3523 76/18639 0.236842105263158 1.25305137666761 0.17725615693828 0.534991310031899 GO:0003707 nuclear steroid receptor activity 7/3523 25/18639 0.28 1.4813851830826 0.179054886483191 0.536892885125867 GO:0008139 nuclear localization sequence binding 7/3523 25/18639 0.28 1.4813851830826 0.179054886483191 0.536892885125867 GO:0090482 vitamin transmembrane transporter activity 9/3523 34/18639 0.264705882352941 1.40046918568733 0.179099057312319 0.536892885125867 GO:0015297 antiporter activity 30/3523 135/18639 0.222222222222222 1.17570252625603 0.188263976896492 0.563095858825544 GO:0004713 protein tyrosine kinase activity 31/3523 140/18639 0.221428571428571 1.17150358866226 0.189287237192377 0.564024766418728 GO:0005518 collagen binding 17/3523 72/18639 0.236111111111111 1.24918393414703 0.189423980288217 0.564024766418728 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 6/3523 21/18639 0.285714285714286 1.51161753375776 0.191783308778708 0.567118694749866 GO:0070182 DNA polymerase binding 6/3523 21/18639 0.285714285714286 1.51161753375776 0.191783308778708 0.567118694749866 GO:0003689 DNA clamp loader activity 35/3523 160/18639 0.21875 1.15733217428328 0.192418149266471 0.567118694749866 GO:0008187 poly-pyrimidine tract binding 8/3523 30/18639 0.266666666666667 1.41084303150724 0.192598291665805 0.567118694749866 GO:0031210 phosphatidylcholine binding 8/3523 30/18639 0.266666666666667 1.41084303150724 0.192598291665805 0.567118694749866 GO:0001046 core promoter sequence-specific DNA binding 11/3523 44/18639 0.25 1.32266534203804 0.196501109644578 0.577330693823007 GO:0008081 phosphoric diester hydrolase activity 20/3523 87/18639 0.229885057471264 1.21624399267865 0.1983515271867 0.581480856741583 GO:0019838 growth factor binding 30/3523 136/18639 0.220588235294118 1.16705765473944 0.200137934830353 0.585425501001562 GO:0003777 microtubule motor activity 16/3523 68/18639 0.235294117647059 1.24486149838874 0.202636606449704 0.591237183534638 GO:0035254 glutamate receptor binding 12/3523 49/18639 0.244897959183673 1.29567217179236 0.203015177478761 0.591237183534638 GO:0008238 exopeptidase activity 23/3523 102/18639 0.225490196078431 1.19299226928921 0.204495010962206 0.591722724398016 GO:0015278 intracellularly gated calcium channel activity 5/3523 17/18639 0.294117647058824 1.55607687298592 0.205409771044793 0.591722724398016 GO:0038191 neuropilin binding 5/3523 17/18639 0.294117647058824 1.55607687298592 0.205409771044793 0.591722724398016 GO:0045125 bioactive lipid receptor activity 5/3523 17/18639 0.294117647058824 1.55607687298592 0.205409771044793 0.591722724398016 GO:1990226 histone methyltransferase binding 5/3523 17/18639 0.294117647058824 1.55607687298592 0.205409771044793 0.591722724398016 GO:0030247 polysaccharide binding 7/3523 26/18639 0.269230769230769 1.42440882988712 0.207564463067969 0.596635512888014 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 13/3523 54/18639 0.240740740740741 1.27367773677737 0.208478197810884 0.597437122997459 GO:0019208 phosphatase regulator activity 26/3523 117/18639 0.222222222222222 1.17570252625603 0.208743091167787 0.597437122997459 GO:0030165 PDZ domain binding 19/3523 83/18639 0.228915662650602 1.21111525295049 0.211511392734061 0.603163552638496 GO:0004177 aminopeptidase activity 10/3523 40/18639 0.25 1.32266534203804 0.211652270730075 0.603163552638496 GO:0004197 cysteine-type endopeptidase activity 20/3523 88/18639 0.227272727272727 1.2024230382164 0.213745871446537 0.607825518803 GO:0016758 hexosyltransferase activity 42/3523 197/18639 0.213197969543147 1.12795826123041 0.215491757164339 0.611441006746442 GO:0005164 tumor necrosis factor receptor binding 8/3523 31/18639 0.258064516129032 1.36533196597475 0.219395999538018 0.611441006746442 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0008035 high-density lipoprotein particle binding 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0009982 pseudouridine synthase activity 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0019855 calcium channel inhibitor activity 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0031994 insulin-like growth factor I binding 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0035673 oligopeptide transmembrane transporter activity 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0046974 histone H3K9 methyltransferase activity 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0061459 L-arginine transmembrane transporter activity 4/3523 13/18639 0.307692307692308 1.62789580558528 0.219621506188293 0.611441006746442 GO:0032813 tumor necrosis factor receptor superfamily binding 12/3523 50/18639 0.24 1.26975872835651 0.224153003038906 0.615371218629064 GO:0008093 cytoskeletal anchor activity 6/3523 22/18639 0.272727272727273 1.44290764585968 0.224276859801556 0.615371218629064 GO:0034062 5'-3' RNA polymerase activity 6/3523 22/18639 0.272727272727273 1.44290764585968 0.224276859801556 0.615371218629064 GO:0046972 histone H4K16 acetyltransferase activity 6/3523 22/18639 0.272727272727273 1.44290764585968 0.224276859801556 0.615371218629064 GO:0061133 endopeptidase activator activity 6/3523 22/18639 0.272727272727273 1.44290764585968 0.224276859801556 0.615371218629064 GO:0097747 RNA polymerase activity 6/3523 22/18639 0.272727272727273 1.44290764585968 0.224276859801556 0.615371218629064 GO:0140784 metal ion sensor activity 6/3523 22/18639 0.272727272727273 1.44290764585968 0.224276859801556 0.615371218629064 GO:0016247 channel regulator activity 36/3523 168/18639 0.214285714285714 1.13371315031832 0.226447061117162 0.620044736419775 GO:0000993 RNA polymerase II complex binding 9/3523 36/18639 0.25 1.32266534203804 0.228524977494161 0.62444685208281 GO:0003727 single-stranded RNA binding 20/3523 89/18639 0.224719101123595 1.18891266700048 0.229671853899249 0.626292036916228 GO:0042562 hormone binding 21/3523 94/18639 0.223404255319149 1.18195626309782 0.231242860672075 0.629283850353516 GO:0017080 sodium channel regulator activity 10/3523 41/18639 0.24390243902439 1.29040521174443 0.23571817097841 0.640150779262429 GO:0016405 CoA-ligase activity 7/3523 27/18639 0.259259259259259 1.3716529472987 0.23762580734404 0.64293614873896 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 98/3523 484/18639 0.202479338842975 1.07124961586552 0.237712085113576 0.64293614873896 GO:0140713 histone chaperone activity 35/3523 164/18639 0.213414634146341 1.12910456027637 0.238272197042136 0.643141214780401 GO:0097110 scaffold protein binding 16/3523 70/18639 0.228571428571429 1.2092940270062 0.238759813371574 0.643150166647971 GO:0000900 mRNA regulatory element binding translation repressor activity 5/3523 18/18639 0.277777777777778 1.46962815782004 0.243106518861091 0.649588444763639 GO:0008308 voltage-gated monoatomic anion channel activity 5/3523 18/18639 0.277777777777778 1.46962815782004 0.243106518861091 0.649588444763639 GO:0008525 phosphatidylcholine transporter activity 5/3523 18/18639 0.277777777777778 1.46962815782004 0.243106518861091 0.649588444763639 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 5/3523 18/18639 0.277777777777778 1.46962815782004 0.243106518861091 0.649588444763639 GO:0005021 vascular endothelial growth factor receptor activity 12/3523 51/18639 0.235294117647059 1.24486149838874 0.246134305311401 0.655042800508097 GO:0016597 amino acid binding 12/3523 51/18639 0.235294117647059 1.24486149838874 0.246134305311401 0.655042800508097 GO:0008017 microtubule binding 57/3523 276/18639 0.206521739130435 1.09263658690099 0.248378402834709 0.659693037928986 GO:0035401 histone H3Y41 kinase activity 25/3523 115/18639 0.217391304347826 1.15014377568525 0.250170222550649 0.660505741023734 GO:0140801 histone H2AXY142 kinase activity 25/3523 115/18639 0.217391304347826 1.15014377568525 0.250170222550649 0.660505741023734 GO:0141108 transporter regulator activity 36/3523 170/18639 0.211764705882353 1.12037534854987 0.250176496788357 0.660505741023734 GO:0001216 DNA-binding transcription activator activity 99/3523 491/18639 0.20162932790224 1.06675249581886 0.250912205758168 0.661133748505649 GO:0016836 hydro-lyase activity 14/3523 61/18639 0.229508196721311 1.21425015006771 0.253057124068623 0.665465070818082 GO:0030551 cyclic nucleotide binding 9/3523 37/18639 0.243243243243243 1.28691763009106 0.254943206118701 0.667780232200464 GO:0043394 proteoglycan binding 9/3523 37/18639 0.243243243243243 1.28691763009106 0.254943206118701 0.667780232200464 GO:0016849 phosphorus-oxygen lyase activity 6/3523 23/18639 0.260869565217391 1.3801725308223 0.25838344059833 0.670182049051918 GO:0042171 lysophosphatidic acid acyltransferase activity 6/3523 23/18639 0.260869565217391 1.3801725308223 0.25838344059833 0.670182049051918 GO:0070577 lysine-acetylated histone binding 6/3523 23/18639 0.260869565217391 1.3801725308223 0.25838344059833 0.670182049051918 GO:0071617 lysophospholipid acyltransferase activity 6/3523 23/18639 0.260869565217391 1.3801725308223 0.25838344059833 0.670182049051918 GO:0099186 structural constituent of postsynapse 6/3523 23/18639 0.260869565217391 1.3801725308223 0.25838344059833 0.670182049051918 GO:0043175 RNA polymerase core enzyme binding 10/3523 42/18639 0.238095238095238 1.25968127813146 0.260728249876495 0.672770437755098 GO:0051879 Hsp90 protein binding 10/3523 42/18639 0.238095238095238 1.25968127813146 0.260728249876495 0.672770437755098 GO:0030971 receptor tyrosine kinase binding 18/3523 81/18639 0.222222222222222 1.17570252625603 0.26090118632822 0.672770437755098 GO:0004705 JUN kinase activity 4/3523 14/18639 0.285714285714286 1.51161753375776 0.264553606164177 0.674332416479898 GO:0008195 phosphatidate phosphatase activity 4/3523 14/18639 0.285714285714286 1.51161753375776 0.264553606164177 0.674332416479898 GO:0008331 high voltage-gated calcium channel activity 4/3523 14/18639 0.285714285714286 1.51161753375776 0.264553606164177 0.674332416479898 GO:0008559 ABC-type xenobiotic transporter activity 4/3523 14/18639 0.285714285714286 1.51161753375776 0.264553606164177 0.674332416479898 GO:0031404 chloride ion binding 4/3523 14/18639 0.285714285714286 1.51161753375776 0.264553606164177 0.674332416479898 GO:0061665 SUMO ligase activity 4/3523 14/18639 0.285714285714286 1.51161753375776 0.264553606164177 0.674332416479898 GO:0140359 ABC-type transporter activity 11/3523 47/18639 0.234042553191489 1.23823989467391 0.265269530757349 0.674861947980383 GO:0036408 histone H3K14 acetyltransferase activity 7/3523 28/18639 0.25 1.32266534203804 0.268974664292892 0.680377817487545 GO:0046875 ephrin receptor binding 7/3523 28/18639 0.25 1.32266534203804 0.268974664292892 0.680377817487545 GO:0097718 disordered domain specific binding 7/3523 28/18639 0.25 1.32266534203804 0.268974664292892 0.680377817487545 GO:0019239 deaminase activity 8/3523 33/18639 0.242424242424242 1.28258457409749 0.276618977947929 0.692146001418312 GO:0003724 RNA helicase activity 17/3523 77/18639 0.220779220779221 1.16806809426736 0.278374491872783 0.692146001418312 GO:0019888 protein phosphatase regulator activity 23/3523 107/18639 0.214953271028037 1.13724496698597 0.280744406888777 0.692146001418312 GO:0000146 microfilament motor activity 9/3523 38/18639 0.236842105263158 1.25305137666761 0.282282006616649 0.692146001418312 GO:0043531 ADP binding 9/3523 38/18639 0.236842105263158 1.25305137666761 0.282282006616649 0.692146001418312 GO:0005520 insulin-like growth factor binding 5/3523 19/18639 0.263157894736842 1.39227930740846 0.28241701960469 0.692146001418312 GO:0042577 lipid phosphatase activity 5/3523 19/18639 0.263157894736842 1.39227930740846 0.28241701960469 0.692146001418312 GO:0043395 heparan sulfate proteoglycan binding 5/3523 19/18639 0.263157894736842 1.39227930740846 0.28241701960469 0.692146001418312 GO:0050145 nucleoside monophosphate kinase activity 5/3523 19/18639 0.263157894736842 1.39227930740846 0.28241701960469 0.692146001418312 GO:0005245 voltage-gated calcium channel activity 10/3523 43/18639 0.232558139534884 1.23038636468654 0.286546335987072 0.692146001418312 GO:0008200 ion channel inhibitor activity 10/3523 43/18639 0.232558139534884 1.23038636468654 0.286546335987072 0.692146001418312 GO:0005126 cytokine receptor binding 56/3523 275/18639 0.203636363636364 1.07737104224189 0.288664283185509 0.692146001418312 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0004445 inositol-polyphosphate 5-phosphatase activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0004862 cAMP-dependent protein kinase inhibitor activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0005031 tumor necrosis factor receptor activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0008140 cAMP response element binding protein binding 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0008239 dipeptidyl-peptidase activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0015203 polyamine transmembrane transporter activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0031996 thioesterase binding 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0035256 G protein-coupled glutamate receptor binding 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0043422 protein kinase B binding 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0140940 histone H2A methyltransferase activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0140999 histone H3K4 trimethyltransferase activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:1905394 retromer complex binding 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:1990259 histone H2AQ104 methyltransferase activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:1990757 ubiquitin ligase activator activity 3/3523 10/18639 0.3 1.58719841044564 0.289262824387924 0.692146001418312 GO:0017046 peptide hormone binding 12/3523 53/18639 0.226415094339623 1.19788559278916 0.292251995291857 0.694082427800867 GO:0030552 cAMP binding 6/3523 24/18639 0.25 1.32266534203804 0.293730665981993 0.694082427800867 GO:0050431 transforming growth factor beta binding 6/3523 24/18639 0.25 1.32266534203804 0.293730665981993 0.694082427800867 GO:0050699 WW domain binding 6/3523 24/18639 0.25 1.32266534203804 0.293730665981993 0.694082427800867 GO:0060229 lipase activator activity 6/3523 24/18639 0.25 1.32266534203804 0.293730665981993 0.694082427800867 GO:0070300 phosphatidic acid binding 6/3523 24/18639 0.25 1.32266534203804 0.293730665981993 0.694082427800867 GO:0140033 acetylation-dependent protein binding 6/3523 24/18639 0.25 1.32266534203804 0.293730665981993 0.694082427800867 GO:0001540 amyloid-beta binding 18/3523 83/18639 0.216867469879518 1.14737234490046 0.297978846018776 0.701669046222067 GO:0051213 dioxygenase activity 20/3523 93/18639 0.21505376344086 1.13777663831229 0.297997998546119 0.701669046222067 GO:0004181 metallocarboxypeptidase activity 7/3523 29/18639 0.241379310344828 1.27705619231259 0.301335555159001 0.704531016287242 GO:0010484 histone H3 acetyltransferase activity 7/3523 29/18639 0.241379310344828 1.27705619231259 0.301335555159001 0.704531016287242 GO:0043236 laminin binding 7/3523 29/18639 0.241379310344828 1.27705619231259 0.301335555159001 0.704531016287242 GO:0106222 lncRNA binding 7/3523 29/18639 0.241379310344828 1.27705619231259 0.301335555159001 0.704531016287242 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 8/3523 34/18639 0.235294117647059 1.24486149838874 0.306625107374271 0.715638211938545 GO:0000774 adenyl-nucleotide exchange factor activity 4/3523 15/18639 0.266666666666667 1.41084303150724 0.3109351570186 0.719376112405402 GO:0004953 icosanoid receptor activity 4/3523 15/18639 0.266666666666667 1.41084303150724 0.3109351570186 0.719376112405402 GO:0034483 heparan sulfate sulfotransferase activity 4/3523 15/18639 0.266666666666667 1.41084303150724 0.3109351570186 0.719376112405402 GO:0042809 nuclear vitamin D receptor binding 4/3523 15/18639 0.266666666666667 1.41084303150724 0.3109351570186 0.719376112405402 GO:0120283 protein serine/threonine kinase binding 4/3523 15/18639 0.266666666666667 1.41084303150724 0.3109351570186 0.719376112405402 GO:0016248 channel inhibitor activity 10/3523 44/18639 0.227272727272727 1.2024230382164 0.313030226087804 0.722963722164529 GO:0001222 transcription corepressor binding 11/3523 49/18639 0.224489795918367 1.18769949080966 0.314903610611759 0.726027768910445 GO:0001786 phosphatidylserine binding 13/3523 59/18639 0.220338983050847 1.16573894552505 0.317019352832456 0.728139565607484 GO:0008186 ATP-dependent activity, acting on RNA 17/3523 79/18639 0.215189873417722 1.13849675010869 0.317464464221938 0.728139565607484 GO:0016835 carbon-oxygen lyase activity 17/3523 79/18639 0.215189873417722 1.13849675010869 0.317464464221938 0.728139565607484 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 5/3523 20/18639 0.25 1.32266534203804 0.322802542205358 0.739106510428821 GO:0015645 fatty acid ligase activity 6/3523 25/18639 0.24 1.26975872835651 0.329944070034247 0.740206143911461 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 6/3523 25/18639 0.24 1.26975872835651 0.329944070034247 0.740206143911461 GO:0120515 fatty acid-CoA ligase activity 6/3523 25/18639 0.24 1.26975872835651 0.329944070034247 0.740206143911461 GO:0001965 G-protein alpha-subunit binding 7/3523 30/18639 0.233333333333333 1.23448765256883 0.3344295049178 0.740206143911461 GO:0043995 histone H4K5 acetyltransferase activity 7/3523 30/18639 0.233333333333333 1.23448765256883 0.3344295049178 0.740206143911461 GO:0043996 histone H4K8 acetyltransferase activity 7/3523 30/18639 0.233333333333333 1.23448765256883 0.3344295049178 0.740206143911461 GO:0043997 histone H4K12 acetyltransferase activity 7/3523 30/18639 0.233333333333333 1.23448765256883 0.3344295049178 0.740206143911461 GO:0098918 structural constituent of synapse 7/3523 30/18639 0.233333333333333 1.23448765256883 0.3344295049178 0.740206143911461 GO:0005343 organic acid:sodium symporter activity 8/3523 35/18639 0.228571428571429 1.2092940270062 0.337271876489461 0.740206143911461 GO:0015036 disulfide oxidoreductase activity 9/3523 40/18639 0.225 1.19039880783423 0.339028957901041 0.740206143911461 GO:0050997 quaternary ammonium group binding 9/3523 40/18639 0.225 1.19039880783423 0.339028957901041 0.740206143911461 GO:0061791 GTPase motor activity 9/3523 40/18639 0.225 1.19039880783423 0.339028957901041 0.740206143911461 GO:0071949 FAD binding 9/3523 40/18639 0.225 1.19039880783423 0.339028957901041 0.740206143911461 GO:1990606 membrane scission GTPase motor activity 9/3523 40/18639 0.225 1.19039880783423 0.339028957901041 0.740206143911461 GO:0008028 monocarboxylic acid transmembrane transporter activity 15/3523 70/18639 0.214285714285714 1.13371315031832 0.339226603600416 0.740206143911461 GO:0016782 transferase activity, transferring sulphur-containing groups 15/3523 70/18639 0.214285714285714 1.13371315031832 0.339226603600416 0.740206143911461 GO:0120013 lipid transfer activity 14/3523 65/18639 0.215384615384615 1.13952706390969 0.339870114032289 0.740206143911461 GO:0008009 chemokine activity 10/3523 45/18639 0.222222222222222 1.17570252625603 0.340034292222276 0.740206143911461 GO:0141110 transporter inhibitor activity 10/3523 45/18639 0.222222222222222 1.17570252625603 0.340034292222276 0.740206143911461 GO:0004714 transmembrane receptor protein tyrosine kinase activity 13/3523 60/18639 0.216666666666667 1.14630996309963 0.340334025539816 0.740206143911461 GO:0000099 sulfur amino acid transmembrane transporter activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0003953 NAD+ nucleosidase activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0004016 adenylate cyclase activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0008046 axon guidance receptor activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0008199 ferric iron binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0008432 JUN kinase binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0008526 phosphatidylinositol transfer activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0015217 ADP transmembrane transporter activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0032050 clathrin heavy chain binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0032404 mismatch repair complex binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0034713 type I transforming growth factor beta receptor binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0070697 activin receptor binding 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0097493 structural molecule activity conferring elasticity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:0140537 transcription regulator activator activity 3/3523 11/18639 0.272727272727273 1.44290764585968 0.34613555374173 0.740206143911461 GO:1902936 phosphatidylinositol bisphosphate binding 23/3523 111/18639 0.207207207207207 1.09626316637387 0.347979577286604 0.742953181087797 GO:0046943 carboxylic acid transmembrane transporter activity 38/3523 188/18639 0.202127659574468 1.06938899994565 0.350371653279391 0.745662749286909 GO:0140597 protein carrier chaperone 38/3523 188/18639 0.202127659574468 1.06938899994565 0.350371653279391 0.745662749286909 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 18/3523 86/18639 0.209302325581395 1.10734772821789 0.356278238740443 0.750243454771592 GO:0004708 MAP kinase kinase activity 4/3523 16/18639 0.25 1.32266534203804 0.357957367986709 0.750243454771592 GO:0005324 long-chain fatty acid transmembrane transporter activity 4/3523 16/18639 0.25 1.32266534203804 0.357957367986709 0.750243454771592 GO:0008142 oxysterol binding 4/3523 16/18639 0.25 1.32266534203804 0.357957367986709 0.750243454771592 GO:0015562 efflux transmembrane transporter activity 4/3523 16/18639 0.25 1.32266534203804 0.357957367986709 0.750243454771592 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 4/3523 16/18639 0.25 1.32266534203804 0.357957367986709 0.750243454771592 GO:0043023 ribosomal large subunit binding 4/3523 16/18639 0.25 1.32266534203804 0.357957367986709 0.750243454771592 GO:0097027 ubiquitin-protein transferase activator activity 4/3523 16/18639 0.25 1.32266534203804 0.357957367986709 0.750243454771592 GO:0051536 iron-sulfur cluster binding 16/3523 76/18639 0.210526315789474 1.11382344592677 0.359498636311111 0.750243454771592 GO:0015291 secondary active transmembrane transporter activity 57/3523 287/18639 0.198606271777003 1.05075852956332 0.361007500108245 0.750243454771592 GO:0005342 organic acid transmembrane transporter activity 38/3523 189/18639 0.201058201058201 1.06373085708879 0.363730463100908 0.750243454771592 GO:0043177 organic acid binding 38/3523 189/18639 0.201058201058201 1.06373085708879 0.363730463100908 0.750243454771592 GO:0005123 death receptor binding 5/3523 21/18639 0.238095238095238 1.25968127813146 0.363746052651186 0.750243454771592 GO:0005248 voltage-gated sodium channel activity 5/3523 21/18639 0.238095238095238 1.25968127813146 0.363746052651186 0.750243454771592 GO:0009975 cyclase activity 5/3523 21/18639 0.238095238095238 1.25968127813146 0.363746052651186 0.750243454771592 GO:0061891 calcium ion sensor activity 5/3523 21/18639 0.238095238095238 1.25968127813146 0.363746052651186 0.750243454771592 GO:0140312 cargo adaptor activity 5/3523 21/18639 0.238095238095238 1.25968127813146 0.363746052651186 0.750243454771592 GO:0005048 signal sequence binding 11/3523 51/18639 0.215686274509804 1.14112304018968 0.366450484215749 0.750243454771592 GO:0004529 DNA exonuclease activity 6/3523 26/18639 0.230769230769231 1.22092185418896 0.36665795212413 0.750243454771592 GO:0008143 poly(A) binding 6/3523 26/18639 0.230769230769231 1.22092185418896 0.36665795212413 0.750243454771592 GO:0015145 monosaccharide transmembrane transporter activity 6/3523 26/18639 0.230769230769231 1.22092185418896 0.36665795212413 0.750243454771592 GO:0005310 dicarboxylic acid transmembrane transporter activity 7/3523 31/18639 0.225806451612903 1.1946654702279 0.367980943986903 0.750243454771592 GO:0070325 lipoprotein particle receptor binding 7/3523 31/18639 0.225806451612903 1.1946654702279 0.367980943986903 0.750243454771592 GO:0001530 lipopolysaccharide binding 9/3523 41/18639 0.219512195121951 1.16136469056998 0.368085116723031 0.750243454771592 GO:0015175 neutral L-amino acid transmembrane transporter activity 9/3523 41/18639 0.219512195121951 1.16136469056998 0.368085116723031 0.750243454771592 GO:0140318 protein transporter activity 9/3523 41/18639 0.219512195121951 1.16136469056998 0.368085116723031 0.750243454771592 GO:0004190 aspartic-type endopeptidase activity 8/3523 36/18639 0.222222222222222 1.17570252625603 0.368342419059547 0.750243454771592 GO:0055106 ubiquitin-protein transferase regulator activity 8/3523 36/18639 0.222222222222222 1.17570252625603 0.368342419059547 0.750243454771592 GO:0051540 metal cluster binding 16/3523 77/18639 0.207792207792208 1.09935820636928 0.380777100426083 0.774382832106949 GO:0050840 extracellular matrix binding 14/3523 67/18639 0.208955223880597 1.10551133065866 0.385459950266913 0.782306923770977 GO:0008514 organic anion transmembrane transporter activity 53/3523 269/18639 0.197026022304833 1.04239796472886 0.391902928204124 0.782306923770977 GO:0004175 endopeptidase activity 79/3523 405/18639 0.195061728395062 1.03200555082474 0.396624938315359 0.782306923770977 GO:0035198 miRNA binding 9/3523 42/18639 0.214285714285714 1.13371315031832 0.397364262226632 0.782306923770977 GO:0023023 MHC protein complex binding 8/3523 37/18639 0.216216216216216 1.14392678230317 0.399624960560469 0.782306923770977 GO:0070001 aspartic-type peptidase activity 8/3523 37/18639 0.216216216216216 1.14392678230317 0.399624960560469 0.782306923770977 GO:0042910 xenobiotic transmembrane transporter activity 7/3523 32/18639 0.21875 1.15733217428328 0.40172365222284 0.782306923770977 GO:0043425 bHLH transcription factor binding 7/3523 32/18639 0.21875 1.15733217428328 0.40172365222284 0.782306923770977 GO:0071813 lipoprotein particle binding 7/3523 32/18639 0.21875 1.15733217428328 0.40172365222284 0.782306923770977 GO:0071814 protein-lipid complex binding 7/3523 32/18639 0.21875 1.15733217428328 0.40172365222284 0.782306923770977 GO:0004857 enzyme inhibitor activity 81/3523 416/18639 0.194711538461538 1.03015281447193 0.401784597482736 0.782306923770977 GO:0000995 RNA polymerase III general transcription initiation factor activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0003995 acyl-CoA dehydrogenase activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0004300 enoyl-CoA hydratase activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0005078 MAP-kinase scaffold activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0005095 GTPase inhibitor activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0005247 voltage-gated chloride channel activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0008504 monoamine transmembrane transporter activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0015269 calcium-activated potassium channel activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0016273 arginine N-methyltransferase activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0016274 protein-arginine N-methyltransferase activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0035251 UDP-glucosyltransferase activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0036009 protein-glutamine N-methyltransferase activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0070008 serine-type exopeptidase activity 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0070410 co-SMAD binding 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:1990459 transferrin receptor binding 3/3523 12/18639 0.25 1.32266534203804 0.402511649140832 0.782306923770977 GO:0005044 scavenger receptor activity 6/3523 27/18639 0.222222222222222 1.17570252625603 0.403524279204156 0.782306923770977 GO:0005385 zinc ion transmembrane transporter activity 6/3523 27/18639 0.222222222222222 1.17570252625603 0.403524279204156 0.782306923770977 GO:0008266 poly(U) RNA binding 6/3523 27/18639 0.222222222222222 1.17570252625603 0.403524279204156 0.782306923770977 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 6/3523 27/18639 0.222222222222222 1.17570252625603 0.403524279204156 0.782306923770977 GO:0016881 acid-amino acid ligase activity 5/3523 22/18639 0.227272727272727 1.2024230382164 0.404766403489314 0.78233642681403 GO:0030169 low-density lipoprotein particle binding 4/3523 17/18639 0.235294117647059 1.24486149838874 0.404895090122684 0.78233642681403 GO:0004521 RNA endonuclease activity 15/3523 73/18639 0.205479452054795 1.08712219893537 0.40530682353016 0.78233642681403 GO:0031406 carboxylic acid binding 37/3523 187/18639 0.197860962566845 1.0468153509178 0.407162636974872 0.78477791277595 GO:0032934 sterol binding 14/3523 68/18639 0.205882352941176 1.08925381109015 0.408513067053958 0.785101813383004 GO:0140223 general transcription initiation factor activity 14/3523 68/18639 0.205882352941176 1.08925381109015 0.408513067053958 0.785101813383004 GO:0061980 regulatory RNA binding 12/3523 58/18639 0.206896551724138 1.09461959341079 0.415304988237067 0.79700148031622 GO:0005003 ephrin receptor activity 11/3523 53/18639 0.207547169811321 1.09806179339007 0.41892135747713 0.800471313280041 GO:0005005 transmembrane-ephrin receptor activity 11/3523 53/18639 0.207547169811321 1.09806179339007 0.41892135747713 0.800471313280041 GO:0016251 RNA polymerase II general transcription initiation factor activity 11/3523 53/18639 0.207547169811321 1.09806179339007 0.41892135747713 0.800471313280041 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 10/3523 48/18639 0.208333333333333 1.10222111836503 0.422710716246067 0.805394305846165 GO:0140693 molecular condensate scaffold activity 10/3523 48/18639 0.208333333333333 1.10222111836503 0.422710716246067 0.805394305846165 GO:0033293 monocarboxylic acid binding 16/3523 79/18639 0.20253164556962 1.07152635304347 0.423733565386164 0.806186496895166 GO:0003684 damaged DNA binding 15/3523 74/18639 0.202702702702703 1.07243135840922 0.42758671562333 0.812353588480375 GO:0051082 unfolded protein binding 24/3523 121/18639 0.198347107438017 1.04938737880704 0.43253069242521 0.818596904327919 GO:0019956 chemokine binding 7/3523 33/18639 0.212121212121212 1.1222615023353 0.435405679912239 0.818596904327919 GO:0030296 protein tyrosine kinase activator activity 7/3523 33/18639 0.212121212121212 1.1222615023353 0.435405679912239 0.818596904327919 GO:0140311 protein sequestering activity 7/3523 33/18639 0.212121212121212 1.1222615023353 0.435405679912239 0.818596904327919 GO:0005525 GTP binding 73/3523 378/18639 0.193121693121693 1.02174148115108 0.439309124530175 0.818596904327919 GO:0019789 SUMO transferase activity 6/3523 28/18639 0.214285714285714 1.13371315031832 0.44021962872541 0.818596904327919 GO:0051119 sugar transmembrane transporter activity 6/3523 28/18639 0.214285714285714 1.13371315031832 0.44021962872541 0.818596904327919 GO:0070888 E-box binding 12/3523 59/18639 0.203389830508475 1.0760667189462 0.440399193021223 0.818596904327919 GO:0015485 cholesterol binding 11/3523 54/18639 0.203703703703704 1.0777273157347 0.445202145994355 0.818596904327919 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 11/3523 54/18639 0.203703703703704 1.0777273157347 0.445202145994355 0.818596904327919 GO:0005283 amino acid:sodium symporter activity 5/3523 23/18639 0.217391304347826 1.15014377568525 0.445428337625698 0.818596904327919 GO:0043274 phospholipase binding 5/3523 23/18639 0.217391304347826 1.15014377568525 0.445428337625698 0.818596904327919 GO:0019001 guanyl nucleotide binding 77/3523 400/18639 0.1925 1.01845231336929 0.449005094904567 0.818596904327919 GO:0032561 guanyl ribonucleotide binding 77/3523 400/18639 0.1925 1.01845231336929 0.449005094904567 0.818596904327919 GO:0005004 GPI-linked ephrin receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0005008 hepatocyte growth factor receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0005009 insulin receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0005011 macrophage colony-stimulating factor receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0005018 platelet-derived growth factor alpha-receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0005020 stem cell factor receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0008288 boss receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0036332 placental growth factor receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0038062 protein tyrosine kinase collagen receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0060175 brain-derived neurotrophic factor receptor activity 10/3523 49/18639 0.204081632653061 1.07972680982697 0.450353563844607 0.818596904327919 GO:0004970 glutamate-gated receptor activity 4/3523 18/18639 0.222222222222222 1.17570252625603 0.451120396197425 0.818596904327919 GO:0015172 acidic amino acid transmembrane transporter activity 4/3523 18/18639 0.222222222222222 1.17570252625603 0.451120396197425 0.818596904327919 GO:0034185 apolipoprotein binding 4/3523 18/18639 0.222222222222222 1.17570252625603 0.451120396197425 0.818596904327919 GO:0050811 GABA receptor binding 4/3523 18/18639 0.222222222222222 1.17570252625603 0.451120396197425 0.818596904327919 GO:0098641 cadherin binding involved in cell-cell adhesion 4/3523 18/18639 0.222222222222222 1.17570252625603 0.451120396197425 0.818596904327919 GO:0099602 neurotransmitter receptor regulator activity 4/3523 18/18639 0.222222222222222 1.17570252625603 0.451120396197425 0.818596904327919 GO:1901611 phosphatidylglycerol binding 4/3523 18/18639 0.222222222222222 1.17570252625603 0.451120396197425 0.818596904327919 GO:0003954 NADH dehydrogenase activity 9/3523 44/18639 0.204545454545455 1.08218073439476 0.455927383108436 0.818596904327919 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0004535 poly(A)-specific ribonuclease activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0005035 death receptor activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0005172 vascular endothelial growth factor receptor binding 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0008253 5'-nucleotidase activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0015651 quaternary ammonium group transmembrane transporter activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0017154 semaphorin receptor activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0039706 co-receptor binding 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0071714 icosanoid transmembrane transporter activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0097157 pre-mRNA intronic binding 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0140666 annealing activity 3/3523 13/18639 0.230769230769231 1.22092185418896 0.457378692026593 0.818596904327919 GO:0043022 ribosome binding 22/3523 112/18639 0.196428571428571 1.03923705445846 0.458297776584013 0.819137883315705 GO:0050660 flavin adenine dinucleotide binding 17/3523 86/18639 0.197674418604651 1.04582840998356 0.461774869118085 0.824243314769915 GO:0042277 peptide binding 48/3523 249/18639 0.192771084337349 1.01988652880041 0.465175444816926 0.829198645257555 GO:0015101 organic cation transmembrane transporter activity 16/3523 81/18639 0.197530864197531 1.04506891222758 0.466789241383202 0.830959936403341 GO:0008376 acetylgalactosaminyltransferase activity 7/3523 34/18639 0.205882352941176 1.08925381109015 0.468793235755417 0.831184802514277 GO:0015035 protein-disulfide reductase activity 7/3523 34/18639 0.205882352941176 1.08925381109015 0.468793235755417 0.831184802514277 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 7/3523 34/18639 0.205882352941176 1.08925381109015 0.468793235755417 0.831184802514277 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 35/3523 181/18639 0.193370165745856 1.02305606566478 0.470322524859424 0.832549752154566 GO:0070851 growth factor receptor binding 27/3523 139/18639 0.194244604316547 1.02768242402955 0.471443835557405 0.832549752154566 GO:0140101 catalytic activity, acting on a tRNA 27/3523 139/18639 0.194244604316547 1.02768242402955 0.471443835557405 0.832549752154566 GO:0005416 amino acid:monoatomic cation symporter activity 6/3523 29/18639 0.206896551724138 1.09461959341079 0.476450256612299 0.836022315267822 GO:0016417 S-acyltransferase activity 6/3523 29/18639 0.206896551724138 1.09461959341079 0.476450256612299 0.836022315267822 GO:0035250 UDP-galactosyltransferase activity 6/3523 29/18639 0.206896551724138 1.09461959341079 0.476450256612299 0.836022315267822 GO:0005006 epidermal growth factor receptor activity 10/3523 50/18639 0.2 1.05813227363043 0.477816970849606 0.836022315267822 GO:0005007 fibroblast growth factor receptor activity 10/3523 50/18639 0.2 1.05813227363043 0.477816970849606 0.836022315267822 GO:0005017 platelet-derived growth factor receptor activity 10/3523 50/18639 0.2 1.05813227363043 0.477816970849606 0.836022315267822 GO:0005019 platelet-derived growth factor beta-receptor activity 10/3523 50/18639 0.2 1.05813227363043 0.477816970849606 0.836022315267822 GO:0008194 UDP-glycosyltransferase activity 28/3523 145/18639 0.193103448275862 1.02164495385007 0.483383742535542 0.843642901259702 GO:0005315 phosphate transmembrane transporter activity 5/3523 24/18639 0.208333333333333 1.10222111836503 0.485348777531937 0.843642901259702 GO:0015149 hexose transmembrane transporter activity 5/3523 24/18639 0.208333333333333 1.10222111836503 0.485348777531937 0.843642901259702 GO:0019957 C-C chemokine binding 5/3523 24/18639 0.208333333333333 1.10222111836503 0.485348777531937 0.843642901259702 GO:0055056 D-glucose transmembrane transporter activity 5/3523 24/18639 0.208333333333333 1.10222111836503 0.485348777531937 0.843642901259702 GO:0022804 active transmembrane transporter activity 87/3523 457/18639 0.190371991247265 1.0071937396701 0.489380726964352 0.847605310638337 GO:0042626 ATPase-coupled transmembrane transporter activity 19/3523 98/18639 0.193877551020408 1.02574046933562 0.491725729623572 0.847605310638337 GO:0015144 carbohydrate transmembrane transporter activity 8/3523 40/18639 0.2 1.05813227363043 0.492774476515606 0.847605310638337 GO:0140662 ATP-dependent protein folding chaperone 8/3523 40/18639 0.2 1.05813227363043 0.492774476515606 0.847605310638337 GO:0003756 protein disulfide isomerase activity 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0015245 fatty acid transmembrane transporter activity 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0016918 retinal binding 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0030506 ankyrin binding 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0031420 alkali metal ion binding 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0046527 glucosyltransferase activity 4/3523 19/18639 0.210526315789474 1.11382344592677 0.49610796328882 0.847605310638337 GO:0170055 lipid transmembrane transporter activity 11/3523 56/18639 0.196428571428571 1.03923705445846 0.497290631735451 0.847605310638337 GO:0010485 histone H4 acetyltransferase activity 7/3523 35/18639 0.2 1.05813227363043 0.501673575571906 0.847605310638337 GO:0005010 insulin-like growth factor receptor activity 10/3523 51/18639 0.196078431372549 1.03738458199062 0.50497952856518 0.847605310638337 GO:0005030 neurotrophin receptor activity 10/3523 51/18639 0.196078431372549 1.03738458199062 0.50497952856518 0.847605310638337 GO:0016500 protein-hormone receptor activity 13/3523 67/18639 0.194029850746269 1.02654623561161 0.507437866212496 0.847605310638337 GO:0005161 platelet-derived growth factor receptor binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0005313 L-glutamate transmembrane transporter activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0008191 metalloendopeptidase inhibitor activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0008474 palmitoyl-(protein) hydrolase activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0008494 translation activator activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0016530 metallochaperone activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0030983 mismatched DNA binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0032036 myosin heavy chain binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0042813 Wnt receptor activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0044548 S100 protein binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0071933 Arp2/3 complex binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0098599 palmitoyl hydrolase activity 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0098847 sequence-specific single stranded DNA binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:1901612 cardiolipin binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:1990825 sequence-specific mRNA binding 3/3523 14/18639 0.214285714285714 1.13371315031832 0.509967351807252 0.847605310638337 GO:0016829 lyase activity 38/3523 200/18639 0.19 1.00522565994891 0.51453651596655 0.853567235806717 GO:0015179 L-amino acid transmembrane transporter activity 12/3523 62/18639 0.193548387096774 1.02399897448106 0.514839876416552 0.853567235806717 GO:0030246 carbohydrate binding 53/3523 280/18639 0.189285714285714 1.00144661611451 0.519799012980126 0.860714575109235 GO:0008137 NADH dehydrogenase (ubiquinone) activity 8/3523 41/18639 0.195121951219512 1.03232416939554 0.523002200101684 0.864940126693694 GO:0047617 fatty acyl-CoA hydrolase activity 5/3523 25/18639 0.2 1.05813227363043 0.524199954406359 0.865842710760752 GO:1901682 sulfur compound transmembrane transporter activity 12/3523 63/18639 0.19047619047619 1.00774502250517 0.539074871626948 0.884405895120077 GO:0001972 retinoic acid binding 4/3523 20/18639 0.2 1.05813227363043 0.539434318559685 0.884405895120077 GO:0016408 C-acyltransferase activity 4/3523 20/18639 0.2 1.05813227363043 0.539434318559685 0.884405895120077 GO:0030742 GTP-dependent protein binding 4/3523 20/18639 0.2 1.05813227363043 0.539434318559685 0.884405895120077 GO:0061608 nuclear import signal receptor activity 4/3523 20/18639 0.2 1.05813227363043 0.539434318559685 0.884405895120077 GO:0140664 ATP-dependent DNA damage sensor activity 4/3523 20/18639 0.2 1.05813227363043 0.539434318559685 0.884405895120077 GO:0016411 acylglycerol O-acyltransferase activity 6/3523 31/18639 0.193548387096774 1.02399897448106 0.546509324667688 0.891628213871964 GO:0017147 Wnt-protein binding 6/3523 31/18639 0.193548387096774 1.02399897448106 0.546509324667688 0.891628213871964 GO:0004520 DNA endonuclease activity 8/3523 42/18639 0.19047619047619 1.00774502250517 0.55256406783699 0.891628213871964 GO:0008307 structural constituent of muscle 8/3523 42/18639 0.19047619047619 1.00774502250517 0.55256406783699 0.891628213871964 GO:0048487 beta-tubulin binding 8/3523 42/18639 0.19047619047619 1.00774502250517 0.55256406783699 0.891628213871964 GO:0016407 acetyltransferase activity 18/3523 96/18639 0.1875 0.991999006528527 0.556496678711202 0.891628213871964 GO:0038064 collagen receptor activity 10/3523 53/18639 0.188679245283019 0.99823799399097 0.557963411385793 0.891628213871964 GO:0005402 carbohydrate:monoatomic cation symporter activity 3/3523 15/18639 0.2 1.05813227363043 0.559725400504415 0.891628213871964 GO:0008252 nucleotidase activity 3/3523 15/18639 0.2 1.05813227363043 0.559725400504415 0.891628213871964 GO:0017081 chloride channel regulator activity 3/3523 15/18639 0.2 1.05813227363043 0.559725400504415 0.891628213871964 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/3523 15/18639 0.2 1.05813227363043 0.559725400504415 0.891628213871964 GO:0061578 K63-linked deubiquitinase activity 3/3523 15/18639 0.2 1.05813227363043 0.559725400504415 0.891628213871964 GO:0140161 monocarboxylate:sodium symporter activity 3/3523 15/18639 0.2 1.05813227363043 0.559725400504415 0.891628213871964 GO:0140776 protein-containing complex destabilizing activity 3/3523 15/18639 0.2 1.05813227363043 0.559725400504415 0.891628213871964 GO:0008066 glutamate receptor activity 5/3523 26/18639 0.192307692307692 1.0174348784908 0.561709954949746 0.891628213871964 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 5/3523 26/18639 0.192307692307692 1.0174348784908 0.561709954949746 0.891628213871964 GO:0016289 acyl-CoA hydrolase activity 5/3523 26/18639 0.192307692307692 1.0174348784908 0.561709954949746 0.891628213871964 GO:0050681 nuclear androgen receptor binding 5/3523 26/18639 0.192307692307692 1.0174348784908 0.561709954949746 0.891628213871964 GO:0120014 phospholipid transfer activity 5/3523 26/18639 0.192307692307692 1.0174348784908 0.561709954949746 0.891628213871964 GO:0019842 vitamin binding 28/3523 150/18639 0.186666666666667 0.987590122055067 0.562537575634679 0.891628213871964 GO:0004536 DNA nuclease activity 12/3523 64/18639 0.1875 0.991999006528527 0.562886937629411 0.891628213871964 GO:0072341 modified amino acid binding 17/3523 91/18639 0.186813186813187 0.988365310533917 0.563872918174389 0.891628213871964 GO:0019213 deacetylase activity 7/3523 37/18639 0.189189189189189 1.00093593451527 0.565177757622506 0.891628213871964 GO:0015171 amino acid transmembrane transporter activity 19/3523 102/18639 0.186274509803922 0.985515352891085 0.568339052837823 0.891628213871964 GO:0015459 potassium channel regulator activity 11/3523 59/18639 0.186440677966102 0.986394492367349 0.572746204112091 0.891628213871964 GO:0008378 galactosyltransferase activity 6/3523 32/18639 0.1875 0.991999006528527 0.579921402924191 0.891628213871964 GO:0030515 snoRNA binding 6/3523 32/18639 0.1875 0.991999006528527 0.579921402924191 0.891628213871964 GO:0120015 sterol transfer activity 6/3523 32/18639 0.1875 0.991999006528527 0.579921402924191 0.891628213871964 GO:0010314 phosphatidylinositol-5-phosphate binding 4/3523 21/18639 0.19047619047619 1.00774502250517 0.580772734067567 0.891628213871964 GO:0015125 bile acid transmembrane transporter activity 4/3523 21/18639 0.19047619047619 1.00774502250517 0.580772734067567 0.891628213871964 GO:0015174 basic amino acid transmembrane transporter activity 4/3523 21/18639 0.19047619047619 1.00774502250517 0.580772734067567 0.891628213871964 GO:0019200 carbohydrate kinase activity 4/3523 21/18639 0.19047619047619 1.00774502250517 0.580772734067567 0.891628213871964 GO:0036122 BMP binding 4/3523 21/18639 0.19047619047619 1.00774502250517 0.580772734067567 0.891628213871964 GO:0008375 acetylglucosaminyltransferase activity 8/3523 43/18639 0.186046511627907 0.984309091749236 0.581333358960326 0.891628213871964 GO:0017069 snRNA binding 10/3523 54/18639 0.185185185185185 0.97975210521336 0.58359097170203 0.891628213871964 GO:1901681 sulfur compound binding 51/3523 275/18639 0.185454545454545 0.981177199184579 0.584902205273016 0.891628213871964 GO:0160215 deacylase activity 12/3523 65/18639 0.184615384615385 0.976737483351165 0.586206084976689 0.891628213871964 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 24/3523 130/18639 0.184615384615385 0.976737483351165 0.58661667075024 0.891628213871964 GO:0001094 TFIID-class transcription factor complex binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0004382 GDP phosphatase activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0005131 growth hormone receptor binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0005345 purine nucleobase transmembrane transporter activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0008190 eukaryotic initiation factor 4E binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0015187 glycine transmembrane transporter activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0031434 mitogen-activated protein kinase kinase binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0031956 medium-chain fatty acid-CoA ligase activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0032052 bile acid binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0032356 oxidized DNA binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0042975 peroxisome proliferator activated receptor binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0043295 glutathione binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0047429 nucleoside triphosphate diphosphatase activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0050815 phosphoserine residue binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0051880 G-quadruplex DNA binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0070739 protein-glutamic acid ligase activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0070740 tubulin-glutamic acid ligase activity 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0097177 mitochondrial ribosome binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0098505 G-rich strand telomeric DNA binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:1990763 arrestin family protein binding 2/3523 10/18639 0.2 1.05813227363043 0.590166566260133 0.891628213871964 GO:0005501 retinoid binding 7/3523 38/18639 0.184210526315789 0.974595515185921 0.595494835001188 0.89763580122767 GO:0019840 isoprenoid binding 7/3523 38/18639 0.184210526315789 0.974595515185921 0.595494835001188 0.89763580122767 GO:0004683 calcium/calmodulin-dependent protein kinase activity 5/3523 27/18639 0.185185185185185 0.97975210521336 0.597661244891926 0.897844042100088 GO:0023026 MHC class II protein complex binding 5/3523 27/18639 0.185185185185185 0.97975210521336 0.597661244891926 0.897844042100088 GO:0035255 ionotropic glutamate receptor binding 5/3523 27/18639 0.185185185185185 0.97975210521336 0.597661244891926 0.897844042100088 GO:0140299 molecular sensor activity 13/3523 71/18639 0.183098591549296 0.968712644872928 0.598577220441092 0.898204009882225 GO:0005521 lamin binding 3/3523 16/18639 0.1875 0.991999006528527 0.606287254162348 0.903646996102803 GO:0015378 sodium:chloride symporter activity 3/3523 16/18639 0.1875 0.991999006528527 0.606287254162348 0.903646996102803 GO:0019841 retinol binding 3/3523 16/18639 0.1875 0.991999006528527 0.606287254162348 0.903646996102803 GO:0055102 lipase inhibitor activity 3/3523 16/18639 0.1875 0.991999006528527 0.606287254162348 0.903646996102803 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/3523 16/18639 0.1875 0.991999006528527 0.606287254162348 0.903646996102803 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 3/3523 16/18639 0.1875 0.991999006528527 0.606287254162348 0.903646996102803 GO:0140313 molecular sequestering activity 10/3523 55/18639 0.181818181818182 0.961938430573117 0.608530993596222 0.905956772198138 GO:0019205 nucleobase-containing compound kinase activity 8/3523 44/18639 0.181818181818182 0.961938430573117 0.609201353594079 0.905956772198138 GO:0003924 GTPase activity 61/3523 331/18639 0.18429003021148 0.97501614337547 0.609929943600704 0.90602568803326 GO:0008649 rRNA methyltransferase activity 4/3523 22/18639 0.181818181818182 0.961938430573117 0.619885251973846 0.916712265725242 GO:0015377 chloride:monoatomic cation symporter activity 4/3523 22/18639 0.181818181818182 0.961938430573117 0.619885251973846 0.916712265725242 GO:0033691 sialic acid binding 4/3523 22/18639 0.181818181818182 0.961938430573117 0.619885251973846 0.916712265725242 GO:0140517 protein-RNA adaptor activity 4/3523 22/18639 0.181818181818182 0.961938430573117 0.619885251973846 0.916712265725242 GO:0048020 CCR chemokine receptor binding 9/3523 50/18639 0.18 0.952319046267386 0.621506437376304 0.918087373565886 GO:0004519 endonuclease activity 23/3523 127/18639 0.181102362204724 0.958151271397632 0.625951694416569 0.923626500205782 GO:0050698 proteoglycan sulfotransferase activity 5/3523 28/18639 0.178571428571429 0.944760958598597 0.631887683188995 0.925386190291262 GO:0051019 mitogen-activated protein kinase binding 5/3523 28/18639 0.178571428571429 0.944760958598597 0.631887683188995 0.925386190291262 GO:0051959 dynein light intermediate chain binding 5/3523 28/18639 0.178571428571429 0.944760958598597 0.631887683188995 0.925386190291262 GO:0019212 phosphatase inhibitor activity 10/3523 56/18639 0.178571428571429 0.944760958598597 0.63271368095726 0.925386190291262 GO:0046915 transition metal ion transmembrane transporter activity 8/3523 45/18639 0.177777777777778 0.940562021004825 0.636077180137669 0.925386190291262 GO:0043021 ribonucleoprotein complex binding 32/3523 177/18639 0.180790960451977 0.956503750174399 0.64057097035827 0.925386190291262 GO:0015020 glucuronosyltransferase activity 6/3523 34/18639 0.176470588235294 0.933646123791555 0.642730887812789 0.925386190291262 GO:0001851 complement component C3b binding 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0010854 adenylate cyclase regulator activity 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0015205 nucleobase transmembrane transporter activity 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0019215 intermediate filament binding 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0042608 T cell receptor binding 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0070990 snRNP binding 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:1900750 oligopeptide binding 2/3523 11/18639 0.181818181818182 0.961938430573117 0.644395680153111 0.925386190291262 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0004549 tRNA-specific ribonuclease activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0004550 nucleoside diphosphate kinase activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0005092 GDP-dissociation inhibitor activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0008429 phosphatidylethanolamine binding 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0008484 sulfuric ester hydrolase activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0008569 minus-end-directed microtubule motor activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0017110 nucleoside diphosphate phosphatase activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0030548 acetylcholine receptor regulator activity 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0045236 CXCR chemokine receptor binding 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0048038 quinone binding 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0051787 misfolded protein binding 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0070402 NADPH binding 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0070403 NAD+ binding 3/3523 17/18639 0.176470588235294 0.933646123791555 0.649442717885133 0.925386190291262 GO:0004602 glutathione peroxidase activity 4/3523 23/18639 0.173913043478261 0.920115020548199 0.656613023415561 0.931557574388798 GO:0008171 O-methyltransferase activity 4/3523 23/18639 0.173913043478261 0.920115020548199 0.656613023415561 0.931557574388798 GO:0031681 G-protein beta-subunit binding 4/3523 23/18639 0.173913043478261 0.920115020548199 0.656613023415561 0.931557574388798 GO:0140102 catalytic activity, acting on a rRNA 4/3523 23/18639 0.173913043478261 0.920115020548199 0.656613023415561 0.931557574388798 GO:0022853 active monoatomic ion transmembrane transporter activity 21/3523 118/18639 0.177966101694915 0.941558379077924 0.657281210242698 0.931557574388798 GO:0004180 carboxypeptidase activity 8/3523 46/18639 0.173913043478261 0.920115020548199 0.661887326138763 0.937085681356373 GO:0003785 actin monomer binding 5/3523 29/18639 0.172413793103448 0.91218299450899 0.664270480392473 0.939458144793614 GO:0005201 extracellular matrix structural constituent 30/3523 168/18639 0.178571428571429 0.944760958598597 0.66628662436952 0.941307060811406 GO:0000049 tRNA binding 14/3523 80/18639 0.175 0.925865739426625 0.66999646127905 0.945239092936811 GO:0005080 protein kinase C binding 9/3523 52/18639 0.173076923076923 0.915691390641717 0.67049339273078 0.945239092936811 GO:0008080 N-acetyltransferase activity 12/3523 69/18639 0.173913043478261 0.920115020548199 0.673408573061681 0.94723415963522 GO:0061733 protein-lysine-acetyltransferase activity 8/3523 47/18639 0.170212765957447 0.900538105217386 0.686574874036728 0.94723415963522 GO:0003746 translation elongation factor activity 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0015280 ligand-gated sodium channel activity 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0015373 monoatomic anion:sodium symporter activity 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0016854 racemase and epimerase activity 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0031690 adrenergic receptor binding 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0035615 clathrin adaptor activity 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0070628 proteasome binding 3/3523 18/18639 0.166666666666667 0.881776894692024 0.689107182222674 0.94723415963522 GO:0004620 phospholipase activity 19/3523 109/18639 0.174311926605505 0.922225376099915 0.690326432996348 0.94723415963522 GO:0004622 lysophospholipase activity 4/3523 24/18639 0.166666666666667 0.881776894692024 0.690865872592286 0.94723415963522 GO:0048027 mRNA 5'-UTR binding 4/3523 24/18639 0.166666666666667 0.881776894692024 0.690865872592286 0.94723415963522 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/3523 24/18639 0.166666666666667 0.881776894692024 0.690865872592286 0.94723415963522 GO:0140612 DNA damage sensor activity 4/3523 24/18639 0.166666666666667 0.881776894692024 0.690865872592286 0.94723415963522 GO:0003720 telomerase activity 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0008179 adenylate cyclase binding 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0015132 prostaglandin transmembrane transporter activity 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0015166 polyol transmembrane transporter activity 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0015368 calcium:monoatomic cation antiporter activity 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0031543 peptidyl-proline dioxygenase activity 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0034452 dynactin binding 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0035197 siRNA binding 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0042301 phosphate ion binding 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0043047 single-stranded telomeric DNA binding 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/3523 12/18639 0.166666666666667 0.881776894692024 0.692772486355567 0.94723415963522 GO:0004864 protein phosphatase inhibitor activity 9/3523 53/18639 0.169811320754717 0.898414194591873 0.693510888914981 0.94723415963522 GO:0016860 intramolecular oxidoreductase activity 9/3523 53/18639 0.169811320754717 0.898414194591873 0.693510888914981 0.94723415963522 GO:0034212 protein N-acetyltransferase activity 9/3523 53/18639 0.169811320754717 0.898414194591873 0.693510888914981 0.94723415963522 GO:0033218 amide binding 44/3523 247/18639 0.178137651821862 0.942465992707264 0.694621445994719 0.94723415963522 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 5/3523 30/18639 0.166666666666667 0.881776894692024 0.694733487563783 0.94723415963522 GO:0017171 serine hydrolase activity 35/3523 198/18639 0.176767676767677 0.935217918612753 0.698515133785035 0.950757092973414 GO:0016409 palmitoyltransferase activity 6/3523 36/18639 0.166666666666667 0.881776894692024 0.699526799537415 0.950757092973414 GO:0045505 dynein intermediate chain binding 6/3523 36/18639 0.166666666666667 0.881776894692024 0.699526799537415 0.950757092973414 GO:0036002 pre-mRNA binding 10/3523 59/18639 0.169491525423729 0.896722265788499 0.700181051903613 0.950757092973414 GO:0001664 G protein-coupled receptor binding 53/3523 297/18639 0.178451178451178 0.944124755932874 0.702835032716608 0.953386030079321 GO:0004402 histone acetyltransferase activity 7/3523 42/18639 0.166666666666667 0.881776894692024 0.704732016363915 0.954983793603346 GO:0015399 primary active transmembrane transporter activity 29/3523 166/18639 0.174698795180723 0.924272166725374 0.711828686708267 0.963617223189173 GO:0016651 oxidoreductase activity, acting on NAD(P)H 15/3523 88/18639 0.170454545454545 0.901817278662297 0.713248426627672 0.964555917068787 GO:0050661 NADP binding 9/3523 54/18639 0.166666666666667 0.881776894692024 0.715494872357571 0.96542094530312 GO:0051287 NAD binding 9/3523 54/18639 0.166666666666667 0.881776894692024 0.715494872357571 0.96542094530312 GO:0008236 serine-type peptidase activity 34/3523 194/18639 0.175257731958763 0.92722931194419 0.716152292005694 0.96542094530312 GO:0008201 heparin binding 30/3523 172/18639 0.174418604651163 0.922789773514909 0.717566544527131 0.96542094530312 GO:0140767 enzyme-substrate adaptor activity 24/3523 139/18639 0.172661870503597 0.913495488026269 0.721867879466564 0.96542094530312 GO:0015271 outward rectifier potassium channel activity 4/3523 25/18639 0.16 0.846505818904343 0.722611761770558 0.96542094530312 GO:0015296 monoatomic anion:monoatomic cation symporter activity 4/3523 25/18639 0.16 0.846505818904343 0.722611761770558 0.96542094530312 GO:0015662 P-type ion transporter activity 4/3523 25/18639 0.16 0.846505818904343 0.722611761770558 0.96542094530312 GO:0019211 phosphatase activator activity 4/3523 25/18639 0.16 0.846505818904343 0.722611761770558 0.96542094530312 GO:0019706 protein-cysteine S-palmitoyltransferase activity 4/3523 25/18639 0.16 0.846505818904343 0.722611761770558 0.96542094530312 GO:0019707 protein-cysteine S-acyltransferase activity 4/3523 25/18639 0.16 0.846505818904343 0.722611761770558 0.96542094530312 GO:0140358 P-type transmembrane transporter activity 4/3523 25/18639 0.16 0.846505818904343 0.722611761770558 0.96542094530312 GO:0008301 DNA binding, bending 3/3523 19/18639 0.157894736842105 0.835367584445075 0.725294535772772 0.967059381030363 GO:0008381 mechanosensitive monoatomic ion channel activity 3/3523 19/18639 0.157894736842105 0.835367584445075 0.725294535772772 0.967059381030363 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/3523 43/18639 0.162790697674419 0.861270455280581 0.728726199747947 0.970660374388438 GO:0002161 aminoacyl-tRNA editing activity 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0003964 RNA-directed DNA polymerase activity 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0005542 folic acid binding 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0030955 potassium ion binding 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0051011 microtubule minus-end binding 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0071837 HMG box domain binding 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/3523 13/18639 0.153846153846154 0.813947902792638 0.735571358051744 0.971978869146981 GO:0008374 O-acyltransferase activity 9/3523 55/18639 0.163636363636364 0.865744587515805 0.7364225877674 0.972136378285395 GO:0022884 macromolecule transmembrane transporter activity 5/3523 32/18639 0.15625 0.826665838773772 0.749778269709826 0.984693187633171 GO:0051059 NF-kappaB binding 5/3523 32/18639 0.15625 0.826665838773772 0.749778269709826 0.984693187633171 GO:0004896 cytokine receptor activity 16/3523 96/18639 0.166666666666667 0.881776894692024 0.750755848074592 0.984693187633171 GO:0016790 thiolester hydrolase activity 7/3523 44/18639 0.159090909090909 0.841696126751477 0.751339008479759 0.984693187633171 GO:0004435 phosphatidylinositol phospholipase C activity 4/3523 26/18639 0.153846153846154 0.813947902792638 0.751866635737979 0.984693187633171 GO:0008157 protein phosphatase 1 binding 4/3523 26/18639 0.153846153846154 0.813947902792638 0.751866635737979 0.984693187633171 GO:0030507 spectrin binding 4/3523 26/18639 0.153846153846154 0.813947902792638 0.751866635737979 0.984693187633171 GO:0050750 low-density lipoprotein particle receptor binding 4/3523 26/18639 0.153846153846154 0.813947902792638 0.751866635737979 0.984693187633171 GO:0030170 pyridoxal phosphate binding 9/3523 56/18639 0.160714285714286 0.850284862738737 0.756281740135299 0.985076352307071 GO:0001614 purinergic nucleotide receptor activity 3/3523 20/18639 0.15 0.793599205222821 0.758093397633905 0.985076352307071 GO:0005326 neurotransmitter transmembrane transporter activity 3/3523 20/18639 0.15 0.793599205222821 0.758093397633905 0.985076352307071 GO:0010851 cyclase regulator activity 3/3523 20/18639 0.15 0.793599205222821 0.758093397633905 0.985076352307071 GO:0015095 magnesium ion transmembrane transporter activity 3/3523 20/18639 0.15 0.793599205222821 0.758093397633905 0.985076352307071 GO:0016502 nucleotide receptor activity 3/3523 20/18639 0.15 0.793599205222821 0.758093397633905 0.985076352307071 GO:0016505 peptidase activator activity involved in apoptotic process 3/3523 20/18639 0.15 0.793599205222821 0.758093397633905 0.985076352307071 GO:0031418 L-ascorbic acid binding 3/3523 20/18639 0.15 0.793599205222821 0.758093397633905 0.985076352307071 GO:0005496 steroid binding 18/3523 108/18639 0.166666666666667 0.881776894692024 0.759760647470838 0.986277751555496 GO:0005506 iron ion binding 26/3523 154/18639 0.168831168831169 0.893228542675037 0.769179140766291 0.997529198181284 GO:0004065 arylsulfatase activity 2/3523 14/18639 0.142857142857143 0.755808766878878 0.773172025759159 0.999206992139236 GO:0015926 glucosidase activity 2/3523 14/18639 0.142857142857143 0.755808766878878 0.773172025759159 0.999206992139236 GO:0043176 amine binding 2/3523 14/18639 0.142857142857143 0.755808766878878 0.773172025759159 0.999206992139236 GO:0016830 carbon-carbon lyase activity 8/3523 51/18639 0.156862745098039 0.829907665592493 0.773482521023444 0.999206992139236 GO:0016504 peptidase activator activity 9/3523 57/18639 0.157894736842105 0.835367584445075 0.775069547712325 0.999312970254337 GO:0070279 vitamin B6 binding 9/3523 57/18639 0.157894736842105 0.835367584445075 0.775069547712325 0.999312970254337 GO:0004364 glutathione transferase activity 4/3523 27/18639 0.148148148148148 0.783801684170688 0.778684964580771 1 GO:0005104 fibroblast growth factor receptor binding 4/3523 27/18639 0.148148148148148 0.783801684170688 0.778684964580771 1 GO:0008320 protein transmembrane transporter activity 4/3523 27/18639 0.148148148148148 0.783801684170688 0.778684964580771 1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/3523 21/18639 0.142857142857143 0.755808766878878 0.787646841561628 1 GO:0001846 opsonin binding 3/3523 21/18639 0.142857142857143 0.755808766878878 0.787646841561628 1 GO:0035613 RNA stem-loop binding 3/3523 21/18639 0.142857142857143 0.755808766878878 0.787646841561628 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/3523 21/18639 0.142857142857143 0.755808766878878 0.787646841561628 1 GO:0072542 protein phosphatase activator activity 3/3523 21/18639 0.142857142857143 0.755808766878878 0.787646841561628 1 GO:0140375 immune receptor activity 26/3523 156/18639 0.166666666666667 0.881776894692024 0.791498514660774 1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 9/3523 58/18639 0.155172413793103 0.820964695058091 0.792791764099617 1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 6/3523 40/18639 0.15 0.793599205222821 0.793856063166662 1 GO:0016831 carboxy-lyase activity 5/3523 34/18639 0.147058823529412 0.778038436492962 0.797072380485445 1 GO:0016866 intramolecular transferase activity 4/3523 28/18639 0.142857142857143 0.755808766878878 0.803151178146066 1 GO:0051537 2 iron, 2 sulfur cluster binding 4/3523 28/18639 0.142857142857143 0.755808766878878 0.803151178146066 1 GO:0016410 N-acyltransferase activity 15/3523 94/18639 0.159574468085106 0.8442544736413 0.804032303846574 1 GO:0016853 isomerase activity 30/3523 180/18639 0.166666666666667 0.881776894692024 0.805196535081794 1 GO:0005539 glycosaminoglycan binding 41/3523 242/18639 0.169421487603306 0.896351719397677 0.805675474284237 1 GO:0004467 long-chain fatty acid-CoA ligase activity 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0016846 carbon-sulfur lyase activity 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0030553 cGMP binding 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0045504 dynein heavy chain binding 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0048531 beta-1,3-galactosyltransferase activity 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0050700 CARD domain binding 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0141050 histone H3K deacetylase activity 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0141051 histone H4K deacetylase activity 2/3523 15/18639 0.133333333333333 0.705421515753619 0.806009968106043 1 GO:0015293 symporter activity 24/3523 146/18639 0.164383561643836 0.869697759148298 0.806219136009641 1 GO:0008146 sulfotransferase activity 8/3523 53/18639 0.150943396226415 0.798590395192776 0.809753937638731 1 GO:0005504 fatty acid binding 7/3523 47/18639 0.148936170212766 0.787970842065213 0.810963849462694 1 GO:0004812 aminoacyl-tRNA ligase activity 6/3523 41/18639 0.146341463414634 0.774243127046655 0.813482126862188 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 6/3523 41/18639 0.146341463414634 0.774243127046655 0.813482126862188 1 GO:0042287 MHC protein binding 6/3523 41/18639 0.146341463414634 0.774243127046655 0.813482126862188 1 GO:0008970 phospholipase A1 activity 3/3523 22/18639 0.136363636363636 0.721453822929838 0.814135513601804 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/3523 22/18639 0.136363636363636 0.721453822929838 0.814135513601804 1 GO:0016298 lipase activity 21/3523 130/18639 0.161538461538462 0.854645297932269 0.819090970183366 1 GO:0042379 chemokine receptor binding 11/3523 72/18639 0.152777777777778 0.808295486801022 0.825000079625994 1 GO:0004629 phospholipase C activity 4/3523 29/18639 0.137931034482759 0.729746395607192 0.825372089786641 1 GO:0051861 glycolipid binding 4/3523 29/18639 0.137931034482759 0.729746395607192 0.825372089786641 1 GO:0038187 pattern recognition receptor activity 7/3523 48/18639 0.145833333333333 0.771554782855521 0.828184759262152 1 GO:0000062 fatty-acyl-CoA binding 2/3523 16/18639 0.125 0.661332671019018 0.834541784383713 1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/3523 16/18639 0.125 0.661332671019018 0.834541784383713 1 GO:0005149 interleukin-1 receptor binding 2/3523 16/18639 0.125 0.661332671019018 0.834541784383713 1 GO:0015385 sodium:proton antiporter activity 2/3523 16/18639 0.125 0.661332671019018 0.834541784383713 1 GO:0030275 LRR domain binding 2/3523 16/18639 0.125 0.661332671019018 0.834541784383713 1 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/3523 16/18639 0.125 0.661332671019018 0.834541784383713 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/3523 16/18639 0.125 0.661332671019018 0.834541784383713 1 GO:0016493 C-C chemokine receptor activity 3/3523 23/18639 0.130434782608696 0.690086265411149 0.837763887129741 1 GO:0017134 fibroblast growth factor binding 3/3523 23/18639 0.130434782608696 0.690086265411149 0.837763887129741 1 GO:0140103 catalytic activity, acting on a glycoprotein 3/3523 23/18639 0.130434782608696 0.690086265411149 0.837763887129741 1 GO:0015370 solute:sodium symporter activity 12/3523 79/18639 0.151898734177215 0.803644764782604 0.838602401353281 1 GO:0022839 monoatomic ion-gated channel activity 4/3523 30/18639 0.133333333333333 0.705421515753619 0.845470336282465 1 GO:0033612 receptor serine/threonine kinase binding 4/3523 30/18639 0.133333333333333 0.705421515753619 0.845470336282465 1 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/3523 43/18639 0.13953488372093 0.738231818811927 0.8482905418511 1 GO:0048029 monosaccharide binding 11/3523 74/18639 0.148648648648649 0.786449662833427 0.851147758372833 1 GO:0052689 carboxylic ester hydrolase activity 14/3523 92/18639 0.152173913043478 0.805100642979674 0.851221410384302 1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 10/3523 68/18639 0.147058823529412 0.778038436492962 0.851958088898536 1 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 19/3523 122/18639 0.155737704918033 0.823955458974514 0.855835585346383 1 GO:0005540 hyaluronic acid binding 3/3523 24/18639 0.125 0.661332671019018 0.858749317777949 1 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/3523 24/18639 0.125 0.661332671019018 0.858749317777949 1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/3523 24/18639 0.125 0.661332671019018 0.858749317777949 1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/3523 24/18639 0.125 0.661332671019018 0.858749317777949 1 GO:0070840 dynein complex binding 3/3523 24/18639 0.125 0.661332671019018 0.858749317777949 1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/3523 17/18639 0.117647058823529 0.62243074919437 0.859221659916857 1 GO:0016805 dipeptidase activity 2/3523 17/18639 0.117647058823529 0.62243074919437 0.859221659916857 1 GO:0032977 membrane insertase activity 2/3523 17/18639 0.117647058823529 0.62243074919437 0.859221659916857 1 GO:0036041 long-chain fatty acid binding 2/3523 17/18639 0.117647058823529 0.62243074919437 0.859221659916857 1 GO:0070492 oligosaccharide binding 2/3523 17/18639 0.117647058823529 0.62243074919437 0.859221659916857 1 GO:1901567 fatty acid derivative binding 2/3523 17/18639 0.117647058823529 0.62243074919437 0.859221659916857 1 GO:0008327 methyl-CpG binding 4/3523 31/18639 0.129032258064516 0.682665982987373 0.863578810654006 1 GO:0047499 calcium-independent phospholipase A2 activity 4/3523 31/18639 0.129032258064516 0.682665982987373 0.863578810654006 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/3523 44/18639 0.136363636363636 0.721453822929838 0.863598678699207 1 GO:0005272 sodium channel activity 7/3523 51/18639 0.137254901960784 0.726169207393431 0.872477345550492 1 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 37/3523 229/18639 0.161572052401747 0.854823015814975 0.876706708291865 1 GO:0000182 rDNA binding 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0005337 nucleoside transmembrane transporter activity 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0005528 FK506 binding 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0008401 retinoic acid 4-hydroxylase activity 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0008519 ammonium channel activity 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0015643 toxic substance binding 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0019911 structural constituent of myelin sheath 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0032395 MHC class II receptor activity 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0043121 neurotrophin binding 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0051378 serotonin binding 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0070513 death domain binding 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0140135 mechanosensitive monoatomic cation channel activity 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0141109 transporter activator activity 1/3523 10/18639 0.1 0.529066136815214 0.877001933299399 1 GO:0001848 complement binding 3/3523 25/18639 0.12 0.634879364178257 0.877313529960775 1 GO:0008483 transaminase activity 3/3523 25/18639 0.12 0.634879364178257 0.877313529960775 1 GO:0120020 cholesterol transfer activity 3/3523 25/18639 0.12 0.634879364178257 0.877313529960775 1 GO:0031369 translation initiation factor binding 4/3523 32/18639 0.125 0.661332671019018 0.879836030788888 1 GO:0008409 5'-3' exonuclease activity 2/3523 18/18639 0.111111111111111 0.587851263128016 0.88048596962863 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/3523 18/18639 0.111111111111111 0.587851263128016 0.88048596962863 1 GO:1990381 ubiquitin-specific protease binding 2/3523 18/18639 0.111111111111111 0.587851263128016 0.88048596962863 1 GO:0061135 endopeptidase regulator activity 29/3523 184/18639 0.157608695652174 0.833854237371805 0.884418249035836 1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/3523 39/18639 0.128205128205128 0.678289918993864 0.884645436060054 1 GO:0001637 G protein-coupled chemoattractant receptor activity 3/3523 26/18639 0.115384615384615 0.610460927094478 0.893676168337661 1 GO:0004950 chemokine receptor activity 3/3523 26/18639 0.115384615384615 0.610460927094478 0.893676168337661 1 GO:0005112 Notch binding 3/3523 26/18639 0.115384615384615 0.610460927094478 0.893676168337661 1 GO:0005227 calcium-activated cation channel activity 3/3523 26/18639 0.115384615384615 0.610460927094478 0.893676168337661 1 GO:0019865 immunoglobulin binding 3/3523 26/18639 0.115384615384615 0.610460927094478 0.893676168337661 1 GO:0051139 metal cation:proton antiporter activity 3/3523 26/18639 0.115384615384615 0.610460927094478 0.893676168337661 1 GO:0097602 cullin family protein binding 3/3523 26/18639 0.115384615384615 0.610460927094478 0.893676168337661 1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/3523 33/18639 0.121212121212121 0.641292287048745 0.894382365773393 1 GO:0005544 calcium-dependent phospholipid binding 7/3523 53/18639 0.132075471698113 0.698766595793679 0.896408683017158 1 GO:0022821 solute:potassium antiporter activity 2/3523 19/18639 0.105263157894737 0.556911722963383 0.898743785376378 1 GO:0034987 immunoglobulin receptor binding 2/3523 19/18639 0.105263157894737 0.556911722963383 0.898743785376378 1 GO:0042834 peptidoglycan binding 2/3523 19/18639 0.105263157894737 0.556911722963383 0.898743785376378 1 GO:0097001 ceramide binding 2/3523 19/18639 0.105263157894737 0.556911722963383 0.898743785376378 1 GO:0120227 acyl-CoA binding 2/3523 19/18639 0.105263157894737 0.556911722963383 0.898743785376378 1 GO:0008172 S-methyltransferase activity 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0019107 myristoyltransferase activity 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0019203 carbohydrate phosphatase activity 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0019206 nucleoside kinase activity 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0019864 IgG binding 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0032794 GTPase activating protein binding 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0034511 U3 snoRNA binding 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0043522 leucine zipper domain binding 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0047676 arachidonate-CoA ligase activity 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0048407 platelet-derived growth factor binding 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0050786 RAGE receptor binding 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:1990948 ubiquitin ligase inhibitor activity 1/3523 11/18639 0.0909090909090909 0.480969215286558 0.900262558614027 1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 8/3523 60/18639 0.133333333333333 0.705421515753619 0.902431261637951 1 GO:0005125 cytokine activity 37/3523 234/18639 0.158119658119658 0.8365575667591 0.905235561129645 1 GO:0030332 cyclin binding 4/3523 34/18639 0.117647058823529 0.62243074919437 0.907357030478453 1 GO:0004252 serine-type endopeptidase activity 27/3523 176/18639 0.153409090909091 0.811635550796067 0.907447202694611 1 GO:0008395 steroid hydroxylase activity 3/3523 27/18639 0.111111111111111 0.587851263128016 0.908050068807273 1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 9/3523 67/18639 0.134328358208955 0.710685855423422 0.908288880957011 1 GO:0140828 metal cation:monoatomic cation antiporter activity 5/3523 41/18639 0.121951219512195 0.645202605872213 0.909300515863841 1 GO:0048306 calcium-dependent protein binding 11/3523 80/18639 0.1375 0.72746593812092 0.911503311331179 1 GO:0042288 MHC class I protein binding 2/3523 20/18639 0.1 0.529066136815214 0.914371606236653 1 GO:0002020 protease binding 20/3523 136/18639 0.147058823529412 0.778038436492962 0.917293784524819 1 GO:0004623 phospholipase A2 activity 4/3523 35/18639 0.114285714285714 0.604647013503102 0.918895754753367 1 GO:0004126 cytidine deaminase activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0004526 ribonuclease P activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0004859 phospholipase inhibitor activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0004875 complement receptor activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0005436 sodium:phosphate symporter activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0005527 macrolide binding 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0010853 cyclase activator activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0016801 hydrolase activity, acting on ether bonds 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0016803 ether hydrolase activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0097371 MDM2/MDM4 family protein binding 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/3523 12/18639 0.0833333333333333 0.440888447346012 0.919125292455706 1 GO:0004497 monooxygenase activity 15/3523 106/18639 0.141509433962264 0.748678495493228 0.919979738868846 1 GO:0005242 inward rectifier potassium channel activity 3/3523 28/18639 0.107142857142857 0.566856575159158 0.920637935686617 1 GO:1904047 S-adenosyl-L-methionine binding 2/3523 21/18639 0.0952380952380952 0.503872511252585 0.927711055149813 1 GO:0008083 growth factor activity 24/3523 162/18639 0.148148148148148 0.783801684170688 0.927924143536608 1 GO:0005507 copper ion binding 8/3523 63/18639 0.126984126984127 0.671830015003447 0.928486810965691 1 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/3523 36/18639 0.111111111111111 0.587851263128016 0.929129034473198 1 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/3523 36/18639 0.111111111111111 0.587851263128016 0.929129034473198 1 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/3523 36/18639 0.111111111111111 0.587851263128016 0.929129034473198 1 GO:0022832 voltage-gated channel activity 26/3523 175/18639 0.148571428571429 0.786041117554033 0.932744023012584 1 GO:0004993 G protein-coupled serotonin receptor activity 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0008417 fucosyltransferase activity 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0031432 titin binding 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0032396 inhibitory MHC class I receptor activity 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0035325 Toll-like receptor binding 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0045159 myosin II binding 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0070700 BMP receptor binding 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:1901338 catecholamine binding 1/3523 13/18639 0.0769230769230769 0.406973951396319 0.934421453656036 1 GO:0015081 sodium ion transmembrane transporter activity 24/3523 164/18639 0.146341463414634 0.774243127046655 0.937251222594548 1 GO:0030547 signaling receptor inhibitor activity 5/3523 44/18639 0.113636363636364 0.601211519108198 0.937620251602028 1 GO:0004407 histone deacetylase activity 2/3523 22/18639 0.0909090909090909 0.480969215286558 0.939068609304614 1 GO:0031683 G-protein beta/gamma-subunit complex binding 2/3523 22/18639 0.0909090909090909 0.480969215286558 0.939068609304614 1 GO:0033558 protein lysine deacetylase activity 2/3523 22/18639 0.0909090909090909 0.480969215286558 0.939068609304614 1 GO:0016769 transferase activity, transferring nitrogenous groups 3/3523 30/18639 0.1 0.529066136815214 0.941203461163144 1 GO:0048019 receptor antagonist activity 3/3523 30/18639 0.1 0.529066136815214 0.941203461163144 1 GO:0015294 solute:monoatomic cation symporter activity 16/3523 116/18639 0.137931034482759 0.729746395607192 0.941556247004233 1 GO:0042605 peptide antigen binding 5/3523 45/18639 0.111111111111111 0.587851263128016 0.945122424596488 1 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/3523 59/18639 0.11864406779661 0.627705586051949 0.946607599289358 1 GO:0005344 oxygen carrier activity 1/3523 14/18639 0.0714285714285714 0.377904383439439 0.946825255801949 1 GO:0015386 potassium:proton antiporter activity 1/3523 14/18639 0.0714285714285714 0.377904383439439 0.946825255801949 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/3523 14/18639 0.0714285714285714 0.377904383439439 0.946825255801949 1 GO:0019763 immunoglobulin receptor activity 1/3523 14/18639 0.0714285714285714 0.377904383439439 0.946825255801949 1 GO:1901474 azole transmembrane transporter activity 1/3523 14/18639 0.0714285714285714 0.377904383439439 0.946825255801949 1 GO:0005212 structural constituent of eye lens 2/3523 23/18639 0.0869565217391304 0.460057510274099 0.948716678083174 1 GO:0015078 proton transmembrane transporter activity 27/3523 185/18639 0.145945945945946 0.772150578054637 0.94873159987213 1 GO:0005244 voltage-gated monoatomic ion channel activity 25/3523 173/18639 0.144508670520231 0.764546440484414 0.949065933964573 1 GO:0005184 neuropeptide hormone activity 3/3523 31/18639 0.0967741935483871 0.51199948724053 0.949520388003409 1 GO:0005452 solute:inorganic anion antiporter activity 3/3523 31/18639 0.0967741935483871 0.51199948724053 0.949520388003409 1 GO:0004866 endopeptidase inhibitor activity 23/3523 161/18639 0.142857142857143 0.755808766878878 0.949659110946992 1 GO:0016209 antioxidant activity 11/3523 86/18639 0.127906976744186 0.6767125005776 0.949824737113649 1 GO:0022843 voltage-gated monoatomic cation channel activity 20/3523 143/18639 0.13986013986014 0.739952638902398 0.951157660631024 1 GO:0005200 structural constituent of cytoskeleton 15/3523 112/18639 0.133928571428571 0.708570718948948 0.951863010733952 1 GO:0046873 metal ion transmembrane transporter activity 72/3523 450/18639 0.16 0.846505818904343 0.953044022167112 1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/3523 39/18639 0.102564102564103 0.542631935195092 0.953199097238841 1 GO:0030414 peptidase inhibitor activity 24/3523 169/18639 0.142011834319527 0.751336525654742 0.956225279175595 1 GO:0047498 calcium-dependent phospholipase A2 activity 3/3523 32/18639 0.09375 0.495999503264263 0.956729114611808 1 GO:0160041 neuropeptide activity 3/3523 32/18639 0.09375 0.495999503264263 0.956729114611808 1 GO:0004089 carbonate dehydratase activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0004129 cytochrome-c oxidase activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0004559 alpha-mannosidase activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0008242 omega peptidase activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0010181 FMN binding 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0015250 water channel activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0015929 hexosaminidase activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0031386 protein tag activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0047372 monoacylglycerol lipase activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0141047 molecular tag activity 1/3523 15/18639 0.0666666666666667 0.352710757876809 0.956883490637371 1 GO:0015295 solute:proton symporter activity 2/3523 24/18639 0.0833333333333333 0.440888447346012 0.956895529020012 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/3523 24/18639 0.0833333333333333 0.440888447346012 0.956895529020012 1 GO:0003925 G protein activity 6/3523 54/18639 0.111111111111111 0.587851263128016 0.957314303263342 1 GO:0046906 tetrapyrrole binding 21/3523 152/18639 0.138157894736842 0.730946636389441 0.960867592136499 1 GO:0015103 inorganic anion transmembrane transporter activity 23/3523 165/18639 0.139393939393939 0.737486130106056 0.962748721077474 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/3523 25/18639 0.08 0.423252909452171 0.96381570285125 1 GO:0015923 mannosidase activity 1/3523 16/18639 0.0625 0.330666335509509 0.965039604387615 1 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/3523 16/18639 0.0625 0.330666335509509 0.965039604387615 1 GO:0017070 U6 snRNA binding 1/3523 16/18639 0.0625 0.330666335509509 0.965039604387615 1 GO:0005253 monoatomic anion channel activity 13/3523 103/18639 0.12621359223301 0.667753376562892 0.966093836488539 1 GO:0051427 hormone receptor binding 3/3523 34/18639 0.0882352941176471 0.466823061895777 0.968345088755378 1 GO:0016859 cis-trans isomerase activity 4/3523 42/18639 0.0952380952380952 0.503872511252585 0.969524210052438 1 GO:0042056 chemoattractant activity 4/3523 42/18639 0.0952380952380952 0.503872511252585 0.969524210052438 1 GO:0008509 monoatomic anion transmembrane transporter activity 20/3523 149/18639 0.134228187919463 0.710155888342569 0.969922304344242 1 GO:0009881 photoreceptor activity 1/3523 17/18639 0.0588235294117647 0.311215374597185 0.971653225917037 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/3523 17/18639 0.0588235294117647 0.311215374597185 0.971653225917037 1 GO:0016018 cyclosporin A binding 1/3523 17/18639 0.0588235294117647 0.311215374597185 0.971653225917037 1 GO:0031489 myosin V binding 1/3523 17/18639 0.0588235294117647 0.311215374597185 0.971653225917037 1 GO:0061134 peptidase regulator activity 32/3523 226/18639 0.141592920353982 0.749120193720657 0.975660070831792 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/3523 36/18639 0.0833333333333333 0.440888447346012 0.976967502849418 1 GO:0005372 water transmembrane transporter activity 1/3523 18/18639 0.0555555555555556 0.293925631564008 0.977016005698708 1 GO:0032393 MHC class I receptor activity 1/3523 18/18639 0.0555555555555556 0.293925631564008 0.977016005698708 1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/3523 18/18639 0.0555555555555556 0.293925631564008 0.977016005698708 1 GO:0046625 sphingolipid binding 2/3523 28/18639 0.0714285714285714 0.377904383439439 0.978739632911328 1 GO:0004867 serine-type endopeptidase inhibitor activity 11/3523 95/18639 0.115789473684211 0.612602895259722 0.980190834389855 1 GO:0030280 structural constituent of skin epidermis 3/3523 37/18639 0.0810810810810811 0.428972543363687 0.980389852273697 1 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/3523 19/18639 0.0526315789473684 0.278455861481692 0.981364462383282 1 GO:0005229 intracellularly calcium-gated chloride channel activity 1/3523 19/18639 0.0526315789473684 0.278455861481692 0.981364462383282 1 GO:0070003 threonine-type peptidase activity 1/3523 19/18639 0.0526315789473684 0.278455861481692 0.981364462383282 1 GO:0099589 serotonin receptor activity 1/3523 19/18639 0.0526315789473684 0.278455861481692 0.981364462383282 1 GO:0141147 intracellularly calcium-gated channel activity 1/3523 19/18639 0.0526315789473684 0.278455861481692 0.981364462383282 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 4/3523 46/18639 0.0869565217391304 0.460057510274099 0.983122505491054 1 GO:0008135 translation factor activity, RNA binding 9/3523 83/18639 0.108433734939759 0.573686172450232 0.983739957225689 1 GO:0005267 potassium channel activity 15/3523 124/18639 0.120967741935484 0.639999359050663 0.984321480334932 1 GO:0043024 ribosomal small subunit binding 1/3523 20/18639 0.05 0.264533068407607 0.984890402180473 1 GO:0043495 protein-membrane adaptor activity 4/3523 47/18639 0.0851063829787234 0.450269052608693 0.985484866175592 1 GO:0180051 translation factor activity 9/3523 84/18639 0.107142857142857 0.566856575159158 0.985549209618634 1 GO:0046982 protein heterodimerization activity 54/3523 369/18639 0.146341463414634 0.774243127046655 0.98742512488483 1 GO:0051428 peptide hormone receptor binding 1/3523 21/18639 0.0476190476190476 0.251936255626293 0.987749369532006 1 GO:0015108 chloride transmembrane transporter activity 14/3523 121/18639 0.115702479338843 0.612142637637438 0.989209946079199 1 GO:0004601 peroxidase activity 5/3523 57/18639 0.087719298245614 0.464093102469486 0.989425552890174 1 GO:0019843 rRNA binding 6/3523 65/18639 0.0923076923076923 0.488368741675582 0.989908479080545 1 GO:0020037 heme binding 17/3523 142/18639 0.119718309859155 0.633389037032299 0.99019462563925 1 GO:0099094 ligand-gated monoatomic cation channel activity 16/3523 136/18639 0.117647058823529 0.62243074919437 0.990815451263347 1 GO:0003743 translation initiation factor activity 4/3523 51/18639 0.0784313725490196 0.414953832796246 0.992145225932876 1 GO:0019003 GDP binding 7/3523 75/18639 0.0933333333333333 0.493795061027533 0.992775676073634 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/3523 34/18639 0.0588235294117647 0.311215374597185 0.992841099985517 1 GO:0019825 oxygen binding 2/3523 34/18639 0.0588235294117647 0.311215374597185 0.992841099985517 1 GO:0005249 voltage-gated potassium channel activity 10/3523 98/18639 0.102040816326531 0.539863404913484 0.993674152556621 1 GO:0015079 potassium ion transmembrane transporter activity 19/3523 160/18639 0.11875 0.628266037468067 0.99383229947027 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 4/3523 53/18639 0.0754716981132075 0.399295197596388 0.994256562732947 1 GO:0005251 delayed rectifier potassium channel activity 1/3523 25/18639 0.04 0.211626454726086 0.994706704541482 1 GO:0005537 D-mannose binding 1/3523 25/18639 0.04 0.211626454726086 0.994706704541482 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/3523 36/18639 0.0555555555555556 0.293925631564008 0.995049288234215 1 GO:0005261 monoatomic cation channel activity 47/3523 341/18639 0.13782991202346 0.729211390918331 0.995232333843679 1 GO:0009055 electron transfer activity 12/3523 116/18639 0.103448275862069 0.547309796705394 0.995944305298547 1 GO:0005216 monoatomic ion channel activity 64/3523 448/18639 0.142857142857143 0.755808766878878 0.996156753450007 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 4/3523 56/18639 0.0714285714285714 0.377904383439439 0.996433227390054 1 GO:0015252 proton channel activity 1/3523 27/18639 0.037037037037037 0.195950421042672 0.996520816717625 1 GO:0008188 neuropeptide receptor activity 3/3523 48/18639 0.0625 0.330666335509509 0.996874439976847 1 GO:0005254 chloride channel activity 7/3523 83/18639 0.0843373493975904 0.446200356350181 0.99759209329583 1 GO:0071855 neuropeptide receptor binding 2/3523 40/18639 0.05 0.264533068407607 0.997649664569516 1 GO:0008528 G protein-coupled peptide receptor activity 12/3523 122/18639 0.0983606557377049 0.520392921457588 0.998018562975853 1 GO:0015106 bicarbonate transmembrane transporter activity 1/3523 32/18639 0.03125 0.165333167754754 0.998781684160315 1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/3523 32/18639 0.03125 0.165333167754754 0.998781684160315 1 GO:0022824 transmitter-gated monoatomic ion channel activity 4/3523 63/18639 0.0634920634920635 0.335915007501723 0.998858785520136 1 GO:0022835 transmitter-gated channel activity 4/3523 63/18639 0.0634920634920635 0.335915007501723 0.998858785520136 1 GO:0042923 neuropeptide binding 1/3523 33/18639 0.0303030303030303 0.160323071762186 0.999012356848185 1 GO:0001653 peptide receptor activity 12/3523 128/18639 0.09375 0.495999503264263 0.999056273296762 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 5/3523 73/18639 0.0684931506849315 0.362374066311791 0.999067348405201 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/3523 91/18639 0.0769230769230769 0.406973951396319 0.999237479721358 1 GO:0016798 hydrolase activity, acting on glycosyl bonds 12/3523 130/18639 0.0923076923076923 0.488368741675582 0.999266881936592 1 GO:0016229 steroid dehydrogenase activity 1/3523 35/18639 0.0285714285714286 0.151161753375776 0.999350971103378 1 GO:0005179 hormone activity 12/3523 132/18639 0.0909090909090909 0.480969215286558 0.999431922757707 1 GO:0022836 gated channel activity 39/3523 318/18639 0.122641509433962 0.648854696094131 0.999473754083816 1 GO:0022829 wide pore channel activity 1/3523 37/18639 0.027027027027027 0.142990847787896 0.999573512607076 1 GO:0098960 postsynaptic neurotransmitter receptor activity 4/3523 69/18639 0.0579710144927536 0.3067050068494 0.999581589627568 1 GO:0003730 mRNA 3'-UTR binding 30/3523 262/18639 0.114503816793893 0.605800920017421 0.99961830597849 1 GO:0008227 G protein-coupled amine receptor activity 1/3523 41/18639 0.024390243902439 0.129040521174443 0.999815869780789 1 GO:0015276 ligand-gated monoatomic ion channel activity 18/3523 186/18639 0.0967741935483871 0.51199948724053 0.999829746611706 1 GO:0022834 ligand-gated channel activity 18/3523 188/18639 0.0957446808510638 0.50655268418478 0.999865929702364 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/3523 122/18639 0.0737704918032787 0.390294691093191 0.999910754385965 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 10/3523 132/18639 0.0757575757575758 0.400807679405465 0.999931643845298 1 GO:0099095 ligand-gated monoatomic anion channel activity 1/3523 47/18639 0.0212765957446809 0.112567263152173 0.999947785676192 1 GO:0003735 structural constituent of ribosome 15/3523 175/18639 0.0857142857142857 0.453485260127327 0.999958776777873 1 GO:0030594 neurotransmitter receptor activity 5/3523 97/18639 0.0515463917525773 0.272714503512997 0.999982178830938 1 GO:0003823 antigen binding 13/3523 174/18639 0.0747126436781609 0.395279297620562 0.999994508008141 1 GO:0030527 structural constituent of chromatin 1/3523 98/18639 0.0102040816326531 0.0539863404913484 0.999999998858471 1 GO:0004984 olfactory receptor activity 1/3523 419/18639 0.00238663484486874 0.0126268767736328 1 1 GO:0030371 translation repressor activity 5/3523 329/18639 0.0151975683890578 0.0804051879658381 1 1 GO:0045182 translation regulator activity 11/3523 356/18639 0.0308988764044944 0.163475491712566 1 1