ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	167/3407	495/18639	0.337373737373737	1.84570269765456	5.95372291754727e-17	7.83509935949221e-14
GO:0019787	ubiquitin-like protein transferase activity	160/3407	479/18639	0.334029227557411	1.82740556866527	7.50652624357881e-16	4.93929426827485e-13
GO:0016755	aminoacyltransferase activity	162/3407	496/18639	0.326612903225806	1.78683237546986	4.75396066319794e-15	1.5822121334154e-12
GO:0030695	GTPase regulator activity	160/3407	489/18639	0.32719836400818	1.79003531163735	5.902318231413e-15	1.5822121334154e-12
GO:0004842	ubiquitin-protein transferase activity	150/3407	449/18639	0.334075723830735	1.82765994026448	6.04808971020699e-15	1.5822121334154e-12
GO:0060589	nucleoside-triphosphatase regulator activity	160/3407	490/18639	0.326530612244898	1.7863821783483	7.21373313107325e-15	1.5822121334154e-12
GO:0140097	catalytic activity, acting on DNA	118/3407	336/18639	0.351190476190476	1.92129124910898	1.03181033002245e-13	1.9398034204422e-11
GO:0004386	helicase activity	64/3407	155/18639	0.412903225806452	2.2589090771372	1.97119069177464e-11	3.24260868796928e-09
GO:0008094	ATP-dependent activity, acting on DNA	78/3407	210/18639	0.371428571428571	2.03200972787119	7.23081735918134e-11	1.05730618274252e-08
GO:0005096	GTPase activator activity	93/3407	271/18639	0.343173431734317	1.87743163900673	1.74350901958003e-10	2.29445786976732e-08
GO:0003713	transcription coactivator activity	89/3407	256/18639	0.34765625	1.90195622064866	1.99748197378139e-10	2.38971479772392e-08
GO:0061659	ubiquitin-like protein ligase activity	117/3407	372/18639	0.314516129032258	1.7206533986006	4.25295380174874e-10	4.66407266925112e-08
GO:0140030	modification-dependent protein binding	66/3407	173/18639	0.38150289017341	2.08712426473208	5.59346483997717e-10	5.66230748416151e-08
GO:0005085	guanyl-nucleotide exchange factor activity	81/3407	230/18639	0.352173913043478	1.92667143094141	6.37945980577143e-10	5.99669221742515e-08
GO:0042393	histone binding	85/3407	247/18639	0.34412955465587	1.88266239190806	8.98597496394989e-10	7.88369536837204e-08
GO:0061630	ubiquitin protein ligase activity	111/3407	353/18639	0.314447592067989	1.7202784468903	1.20528256277179e-09	9.91344907879798e-08
GO:0000217	DNA secondary structure binding	24/3407	39/18639	0.615384615384615	3.36664333611795	2.58442132162206e-09	2.00064615250272e-07
GO:0016779	nucleotidyltransferase activity	54/3407	136/18639	0.397058823529412	2.17222759370845	3.86184058621748e-09	2.82343456192345e-07
GO:0106310	protein serine kinase activity	110/3407	361/18639	0.304709141274238	1.66700137487835	1.00813546741605e-08	6.98266460589223e-07
GO:0003678	DNA helicase activity	35/3407	74/18639	0.472972972972973	2.58753837488795	1.06672816605197e-08	7.01907133262198e-07
GO:0004677	DNA-dependent protein kinase activity	80/3407	246/18639	0.32520325203252	1.77912046217615	4.85890601334871e-08	2.52367676142801e-06
GO:0140857	histone H3T45 kinase activity	80/3407	246/18639	0.32520325203252	1.77912046217615	4.85890601334871e-08	2.52367676142801e-06
GO:0031267	small GTPase binding	89/3407	283/18639	0.314487632508834	1.72049749995074	5.13064170223594e-08	2.52367676142801e-06
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	79/3407	243/18639	0.325102880658436	1.77857135092239	5.9657656882627e-08	2.52367676142801e-06
GO:0000400	four-way junction DNA binding	14/3407	18/18639	0.777777777777778	4.25506310537129	6.61058509589141e-08	2.52367676142801e-06
GO:0035173	histone kinase activity	107/3407	360/18639	0.297222222222222	1.62604197240974	6.71344977499868e-08	2.52367676142801e-06
GO:0003714	transcription corepressor activity	69/3407	204/18639	0.338235294117647	1.85041609834424	7.24624656633387e-08	2.52367676142801e-06
GO:0140658	ATP-dependent chromatin remodeler activity	57/3407	158/18639	0.360759493670886	1.97364138612611	8.14489683448692e-08	2.52367676142801e-06
GO:0003697	single-stranded DNA binding	47/3407	121/18639	0.388429752066116	2.12501970905792	8.55405016822009e-08	2.52367676142801e-06
GO:0004676	3-phosphoinositide-dependent protein kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0004711	ribosomal protein S6 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0035175	histone H3S10 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0035979	histone H2AXS139 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0044022	histone H3S28 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0044023	histone H4S1 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0044024	histone H2AS1 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0044025	histone H2BS14 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0072354	histone H3T3 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0072371	histone H2AS121 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0072518	Rho-dependent protein serine/threonine kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0140823	histone H2BS36 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0140855	histone H3S57 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0140995	histone H2A kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0140997	histone H4 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0140998	histone H2B kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:1990244	histone H2AT120 kinase activity	79/3407	245/18639	0.322448979591837	1.76405240111894	8.82136253994595e-08	2.52367676142801e-06
GO:0140297	DNA-binding transcription factor binding	136/3407	488/18639	0.278688524590164	1.52464790426653	9.17309740910704e-08	2.56846727454997e-06
GO:0015631	tubulin binding	112/3407	385/18639	0.290909090909091	1.59150412252848	1.16206101052157e-07	3.18598393717998e-06
GO:0004674	protein serine/threonine kinase activity	123/3407	433/18639	0.284064665127021	1.55405966929925	1.21259428164745e-07	3.20162769192589e-06
GO:0015616	DNA translocase activity	55/3407	152/18639	0.361842105263158	1.97956413266804	1.21642389510862e-07	3.20162769192589e-06
GO:0035402	histone H3T11 kinase activity	79/3407	247/18639	0.319838056680162	1.74976857600867	1.29439278347173e-07	3.27580942893999e-06
GO:0035403	histone H3T6 kinase activity	79/3407	247/18639	0.319838056680162	1.74976857600867	1.29439278347173e-07	3.27580942893999e-06
GO:0004679	AMP-activated protein kinase activity	79/3407	248/18639	0.318548387096774	1.74271305755702	1.5635085352988e-07	3.8125470486737e-06
GO:0061775	cohesin loader activity	55/3407	153/18639	0.359477124183007	1.96662580500354	1.56441900173541e-07	3.8125470486737e-06
GO:0051020	GTPase binding	95/3407	315/18639	0.301587301587302	1.64992242861336	1.71054125994205e-07	4.09285872378861e-06
GO:0017116	single-stranded DNA helicase activity	28/3407	58/18639	0.482758620689655	2.64107365160977	1.80673963364018e-07	4.24583813905442e-06
GO:0141003	histone H2AX kinase activity	104/3407	354/18639	0.293785310734463	1.60723933277947	1.92344488966285e-07	4.44079556981809e-06
GO:0003725	double-stranded RNA binding	33/3407	75/18639	0.44	2.40714998532433	2.39634973193629e-07	5.20770381524879e-06
GO:0000510	H3-H4 histone complex chaperone activity	54/3407	151/18639	0.357615894039735	1.95644339565795	2.45347748134821e-07	5.20770381524879e-06
GO:0140584	chromatin extrusion motor activity	54/3407	151/18639	0.357615894039735	1.95644339565795	2.45347748134821e-07	5.20770381524879e-06
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	54/3407	151/18639	0.357615894039735	1.95644339565795	2.45347748134821e-07	5.20770381524879e-06
GO:0140849	ATP-dependent H2AZ histone chaperone activity	54/3407	151/18639	0.357615894039735	1.95644339565795	2.45347748134821e-07	5.20770381524879e-06
GO:0140996	histone H3 kinase activity	104/3407	357/18639	0.291316526610644	1.59373311989897	3.02150664590827e-07	6.31159166034172e-06
GO:0140674	ATP-dependent histone chaperone activity	54/3407	152/18639	0.355263157894737	1.94357205752862	3.13511925335781e-07	6.44658896471701e-06
GO:0003689	DNA clamp loader activity	56/3407	160/18639	0.35	1.91477839741708	3.36817644805086e-07	6.81926185482296e-06
GO:0016887	ATP hydrolysis activity	117/3407	417/18639	0.280575539568345	1.53497137716888	4.91821749346163e-07	9.806627608175e-06
GO:0009378	four-way junction helicase activity	24/3407	48/18639	0.5	2.73539771059583	5.97647242711326e-07	1.15662319324721e-05
GO:0043138	3'-5' DNA helicase activity	24/3407	48/18639	0.5	2.73539771059583	5.97647242711326e-07	1.15662319324721e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	100/3407	349/18639	0.286532951289398	1.56756315793457	1.16705384798202e-06	2.22585922310774e-05
GO:0061749	forked DNA-dependent helicase activity	23/3407	47/18639	0.48936170212766	2.67719775930656	1.65956301378782e-06	3.07603510724615e-05
GO:1990518	single-stranded 3'-5' DNA helicase activity	23/3407	47/18639	0.48936170212766	2.67719775930656	1.65956301378782e-06	3.07603510724615e-05
GO:0140104	molecular carrier activity	76/3407	249/18639	0.305220883534137	1.66980101209063	1.70921879582927e-06	3.12407213237683e-05
GO:0140713	histone chaperone activity	55/3407	164/18639	0.335365853658537	1.83471797661916	1.98683843429501e-06	3.58175257470169e-05
GO:0036121	double-stranded DNA helicase activity	23/3407	48/18639	0.479166666666667	2.62142280598767	2.63652552317818e-06	4.68873998446282e-05
GO:0044389	ubiquitin-like protein ligase binding	92/3407	322/18639	0.285714285714286	1.56308440605476	3.50219148995511e-06	6.1451786677079e-05
GO:0016791	phosphatase activity	79/3407	273/18639	0.289377289377289	1.58312394972213	1.00292254350401e-05	0.000173663956217273
GO:0004715	non-membrane spanning protein tyrosine kinase activity	21/3407	45/18639	0.466666666666667	2.55303786322278	1.20095291065452e-05	0.00020525377018459
GO:0140033	acetylation-dependent protein binding	14/3407	24/18639	0.583333333333333	3.19129732902847	1.39524137904597e-05	0.000235402263439039
GO:0000287	magnesium ion binding	68/3407	230/18639	0.295652173913043	1.61745255930884	1.88989326123255e-05	0.000314822725542029
GO:0140597	protein carrier chaperone	58/3407	188/18639	0.308510638297872	1.68779858738892	1.9372453958785e-05	0.000318676867622013
GO:0031625	ubiquitin protein ligase binding	84/3407	302/18639	0.278145695364238	1.52167819662285	2.71099189145537e-05	0.000440452509772255
GO:0042578	phosphoric ester hydrolase activity	97/3407	363/18639	0.267217630853994	1.46189299133772	3.91160591866497e-05	0.000627765047434524
GO:0070577	lysine-acetylated histone binding	13/3407	23/18639	0.565217391304348	3.09218871632572	4.5168797446723e-05	0.000716170330601054
GO:0008017	microtubule binding	77/3407	276/18639	0.278985507246377	1.52627263562231	5.13904334121507e-05	0.000805116790123694
GO:0003684	damaged DNA binding	28/3407	74/18639	0.378378378378378	2.07003069991036	5.81724125884543e-05	0.00089017319728379
GO:0031491	nucleosome binding	28/3407	74/18639	0.378378378378378	2.07003069991036	5.81724125884543e-05	0.00089017319728379
GO:0016922	nuclear receptor binding	44/3407	137/18639	0.321167883211679	1.75704378490827	6.5652679723666e-05	0.00099309110938327
GO:0004518	nuclease activity	61/3407	209/18639	0.291866028708134	1.59673933345785	7.4574054059777e-05	0.00111522108116666
GO:0051010	microtubule plus-end binding	12/3407	21/18639	0.571428571428571	3.12616881210952	7.73755739270821e-05	0.00114411522795551
GO:0140852	histone ubiquitin ligase activity	9/3407	13/18639	0.692307692307692	3.78747375313269	7.89971823666133e-05	0.00115511435549404
GO:0140938	histone H3 methyltransferase activity	20/3407	47/18639	0.425531914893617	2.32799805157092	9.86214540877692e-05	0.001414431642092
GO:0140463	chromatin-protein adaptor activity	22/3407	54/18639	0.407407407407407	2.22884257900401	9.8881239416766e-05	0.001414431642092
GO:0003688	DNA replication origin binding	10/3407	16/18639	0.625	3.41924713824479	0.00011173565979045	0.00158111965897024
GO:0004197	cysteine-type endopeptidase activity	31/3407	88/18639	0.352272727272727	1.92721202337434	0.000116051540991552	0.00162472157388173
GO:0019207	kinase regulator activity	78/3407	287/18639	0.271777003484321	1.48683638624721	0.000118613246611145	0.00164310560568702
GO:0140098	catalytic activity, acting on RNA	100/3407	387/18639	0.258397932816537	1.4136422276981	0.000121824066301975	0.00167000490888957
GO:0140035	ubiquitin-like protein reader activity	12/3407	22/18639	0.545454545454545	2.98407022974091	0.0001419173993022	0.00192539481939892
GO:0042162	telomeric DNA binding	17/3407	38/18639	0.447368421052632	2.44746110948048	0.000155017027972679	0.00208165723277598
GO:0001222	transcription corepressor binding	20/3407	49/18639	0.408163265306122	2.23297772293537	0.000196519972117345	0.00261232609400431
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	23/3407	60/18639	0.383333333333333	2.09713824479014	0.000206939304347632	0.00272332124521484
GO:0008168	methyltransferase activity	58/3407	204/18639	0.284313725490196	1.55542222759371	0.000238643014551818	0.00310109490184024
GO:0030145	manganese ion binding	25/3407	68/18639	0.367647058823529	2.01132184602635	0.000241295644702346	0.00310109490184024
GO:0035091	phosphatidylinositol binding	76/3407	284/18639	0.267605633802817	1.46401567609354	0.000242714874536128	0.00310109490184024
GO:0003887	DNA-directed DNA polymerase activity	12/3407	23/18639	0.521739130434783	2.85432804583913	0.000247461328599084	0.00313133758111918
GO:0140034	methylation-dependent protein binding	27/3407	76/18639	0.355263157894737	1.94357205752862	0.000266310981018723	0.00333776429543466
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	8/3407	12/18639	0.666666666666667	3.64719694746111	0.000302783680678798	0.00365562682360824
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	8/3407	12/18639	0.666666666666667	3.64719694746111	0.000302783680678798	0.00365562682360824
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	8/3407	12/18639	0.666666666666667	3.64719694746111	0.000302783680678798	0.00365562682360824
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	8/3407	12/18639	0.666666666666667	3.64719694746111	0.000302783680678798	0.00365562682360824
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	49/3407	167/18639	0.293413173652695	1.60520344693648	0.000315669933979613	0.00377656030106519
GO:0019887	protein kinase regulator activity	69/3407	255/18639	0.270588235294118	1.48033287867539	0.000324999201021607	0.0038531436805805
GO:0070566	adenylyltransferase activity	14/3407	30/18639	0.466666666666667	2.55303786322278	0.0003433783440662	0.00403469554277785
GO:0051219	phosphoprotein binding	31/3407	93/18639	0.333333333333333	1.82359847373055	0.000360535530994418	0.00419880317512083
GO:0045296	cadherin binding	86/3407	334/18639	0.25748502994012	1.40864792282181	0.000395725894800939	0.00456820418910558
GO:0035064	methylated histone binding	26/3407	74/18639	0.351351351351351	1.92217136420248	0.000418651611030471	0.00479083060970522
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	10/3407	18/18639	0.555555555555556	3.03933078955092	0.000426817163465111	0.00484216713034557
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	17/3407	41/18639	0.414634146341463	2.26837858927459	0.00046836928744146	0.0052287175248355
GO:0008234	cysteine-type peptidase activity	53/3407	187/18639	0.283422459893048	1.55054629584577	0.000468836373807439	0.0052287175248355
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	7/3407	10/18639	0.7	3.82955679483416	0.000483869909880743	0.00535103194456352
GO:0042054	histone methyltransferase activity	24/3407	67/18639	0.358208955223881	1.95968791206866	0.00049743509673426	0.00545520489418572
GO:0008276	protein methyltransferase activity	31/3407	95/18639	0.326315789473684	1.78520692691517	0.000546464324017744	0.00594336405295331
GO:0016741	transferase activity, transferring one-carbon groups	59/3407	215/18639	0.274418604651163	1.50128804581539	0.000577212897575363	0.00622632928859982
GO:0140566	histone reader activity	15/3407	35/18639	0.428571428571429	2.34462660908214	0.000658360100454934	0.00695734539695548
GO:0046975	histone H3K36 methyltransferase activity	8/3407	13/18639	0.615384615384615	3.36664333611795	0.000660842077978294	0.00695734539695548
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	8/3407	13/18639	0.615384615384615	3.36664333611795	0.000660842077978294	0.00695734539695548
GO:0004540	RNA nuclease activity	37/3407	121/18639	0.305785123966942	1.67288785606687	0.000696667761533642	0.0072763077315736
GO:0140036	ubiquitin-modified protein reader activity	10/3407	19/18639	0.526315789473684	2.87936601115351	0.000753808778661949	0.00781112088755216
GO:0016279	protein-lysine N-methyltransferase activity	24/3407	69/18639	0.347826086956522	1.90288536389275	0.000809809513799079	0.00832585406374678
GO:0048156	tau protein binding	17/3407	43/18639	0.395348837209302	2.1628726083781	0.00089937002566227	0.00917496863388796
GO:0008408	3'-5' exonuclease activity	21/3407	58/18639	0.362068965517241	1.98080523870733	0.000930669939357525	0.00942124338611156
GO:0019783	ubiquitin-like protein peptidase activity	38/3407	127/18639	0.299212598425197	1.63693091342743	0.000940378811263983	0.00944685889788856
GO:0016278	lysine N-methyltransferase activity	24/3407	70/18639	0.342857142857143	1.87570128726571	0.00102162030718684	0.0101852448807415
GO:0001221	transcription coregulator binding	35/3407	115/18639	0.304347826086957	1.66502469340616	0.00105045053525915	0.0103939316120379
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	11/3407	23/18639	0.478260869565217	2.61646737535254	0.00115414407791301	0.0112507674558039
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	11/3407	23/18639	0.478260869565217	2.61646737535254	0.00115414407791301	0.0112507674558039
GO:0032182	ubiquitin-like protein binding	36/3407	120/18639	0.3	1.6412386263575	0.00119789799312283	0.0115205303165033
GO:0070063	RNA polymerase binding	21/3407	59/18639	0.355932203389831	1.94723226855974	0.00119932572443841	0.0115205303165033
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	9/3407	17/18639	0.529411764705882	2.89630345827794	0.00132277226449223	0.0125235129501567
GO:0004659	prenyltransferase activity	9/3407	17/18639	0.529411764705882	2.89630345827794	0.00132277226449223	0.0125235129501567
GO:0004843	cysteine-type deubiquitinase activity	33/3407	108/18639	0.305555555555556	1.67163193425301	0.00133511973912497	0.0125501255477748
GO:0004536	DNA nuclease activity	22/3407	64/18639	0.34375	1.88058592603463	0.00156530579107214	0.0146095207166733
GO:0052866	phosphatidylinositol phosphate phosphatase activity	14/3407	34/18639	0.411764705882353	2.25268046754951	0.00158351099707693	0.0146753554376989
GO:0051539	4 iron, 4 sulfur cluster binding	17/3407	45/18639	0.377777777777778	2.06674493689463	0.00162928198697295	0.0149939517122826
GO:0019209	kinase activator activity	42/3407	148/18639	0.283783783783784	1.55252302493277	0.00167134337247769	0.0152742213762544
GO:0004721	phosphoprotein phosphatase activity	48/3407	175/18639	0.274285714285714	1.50056102981257	0.00179999036726791	0.0163216647362855
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	15/3407	38/18639	0.394736842105263	2.15952450836513	0.00181076219718669	0.0163216647362855
GO:0004402	histone acetyltransferase activity	16/3407	42/18639	0.380952380952381	2.08411254140635	0.00199934192465809	0.0178988705636057
GO:0101005	deubiquitinase activity	34/3407	115/18639	0.295652173913043	1.61745255930884	0.00211431129951962	0.0188002275011339
GO:0000175	3'-5'-RNA exonuclease activity	14/3407	35/18639	0.4	2.18831816847667	0.0022002782614916	0.0189252692295618
GO:0005154	epidermal growth factor receptor binding	14/3407	35/18639	0.4	2.18831816847667	0.0022002782614916	0.0189252692295618
GO:0010485	histone H4 acetyltransferase activity	14/3407	35/18639	0.4	2.18831816847667	0.0022002782614916	0.0189252692295618
GO:0034061	DNA polymerase activity	14/3407	35/18639	0.4	2.18831816847667	0.0022002782614916	0.0189252692295618
GO:0043015	gamma-tubulin binding	14/3407	35/18639	0.4	2.18831816847667	0.0022002782614916	0.0189252692295618
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	7/3407	12/18639	0.583333333333333	3.19129732902847	0.00226441714141341	0.0193504737538964
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	11/3407	25/18639	0.44	2.40714998532433	0.00266048491799333	0.0225883751747046
GO:0001784	phosphotyrosine residue binding	17/3407	47/18639	0.361702127659574	1.97879834383528	0.00280306480154539	0.0234957533683678
GO:0061733	protein-lysine-acetyltransferase activity	17/3407	47/18639	0.361702127659574	1.97879834383528	0.00280306480154539	0.0234957533683678
GO:0030295	protein kinase activator activity	39/3407	139/18639	0.280575539568345	1.53497137716888	0.00298273905351748	0.0246873244932642
GO:0140767	enzyme-substrate adaptor activity	39/3407	139/18639	0.280575539568345	1.53497137716888	0.00298273905351748	0.0246873244932642
GO:0005484	SNAP receptor activity	14/3407	36/18639	0.388888888888889	2.12753155268565	0.00300254375685282	0.0246959224001144
GO:0045309	protein phosphorylated amino acid binding	20/3407	59/18639	0.338983050847458	1.85450692243785	0.0030225518144857	0.0247060757010135
GO:0016407	acetyltransferase activity	29/3407	96/18639	0.302083333333333	1.65263611681832	0.00305321283694376	0.0248026425519629
GO:0050321	tau-protein kinase activity	10/3407	22/18639	0.454545454545455	2.48672519145076	0.00309699423841445	0.0250039534831498
GO:0043178	alcohol binding	28/3407	92/18639	0.304347826086957	1.66502469340616	0.0031674184855443	0.0254166019937579
GO:0010484	histone H3 acetyltransferase activity	12/3407	29/18639	0.413793103448276	2.26377741566552	0.00321608696435075	0.0254962075005156
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	12/3407	29/18639	0.413793103448276	2.26377741566552	0.00321608696435075	0.0254962075005156
GO:0004532	RNA exonuclease activity	15/3407	40/18639	0.375	2.05154828294687	0.00326874473888098	0.0256051671212344
GO:0030331	nuclear estrogen receptor binding	15/3407	40/18639	0.375	2.05154828294687	0.00326874473888098	0.0256051671212344
GO:0004527	exonuclease activity	26/3407	84/18639	0.30952380952381	1.69334143989266	0.00338425321021276	0.026353119672426
GO:0004713	protein tyrosine kinase activity	39/3407	140/18639	0.278571428571429	1.52400729590339	0.00341935244681403	0.0264698107059251
GO:0140789	histone phosphatase activity	38/3407	136/18639	0.279411764705882	1.52860460298002	0.00361491042160106	0.0278200123674094
GO:0034450	ubiquitin-ubiquitin ligase activity	8/3407	16/18639	0.5	2.73539771059583	0.00392146535799627	0.030003769832111
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/3407	10/18639	0.6	3.282477252715	0.00396899399922919	0.0300183684079633
GO:1905394	retromer complex binding	6/3407	10/18639	0.6	3.282477252715	0.00396899399922919	0.0300183684079633
GO:0017124	SH3 domain binding	33/3407	115/18639	0.28695652173913	1.56988042521152	0.00409513615435123	0.0307954238807212
GO:0046974	histone H3K9 methyltransferase activity	7/3407	13/18639	0.538461538461538	2.9458129191032	0.00413525471542105	0.0309204273039438
GO:0008170	N-methyltransferase activity	29/3407	98/18639	0.295918367346939	1.61890884912815	0.00424760438480399	0.0315810585898421
GO:0051540	metal cluster binding	24/3407	77/18639	0.311688311688312	1.70518298842338	0.00430724581403255	0.0318445814116115
GO:0043539	protein serine/threonine kinase activator activity	23/3407	73/18639	0.315068493150685	1.72367526969052	0.00442329011835663	0.0325198312612141
GO:0002039	p53 binding	22/3407	69/18639	0.318840579710145	1.74431158356836	0.00452392652855733	0.0330749295087858
GO:0016763	pentosyltransferase activity	17/3407	49/18639	0.346938775510204	1.89803106449507	0.00460535641789501	0.033484248872651
GO:0035591	signaling adaptor activity	36/3407	129/18639	0.27906976744186	1.52673360591395	0.00463190954977165	0.033492269052195
GO:0052745	inositol phosphate phosphatase activity	9/3407	20/18639	0.45	2.46185793953625	0.00539885090781245	0.0388245234682032
GO:0004520	DNA endonuclease activity	15/3407	42/18639	0.357142857142857	1.95385550756845	0.00557309758601819	0.0396443049902699
GO:0019894	kinesin binding	15/3407	42/18639	0.357142857142857	1.95385550756845	0.00557309758601819	0.0396443049902699
GO:0030276	clathrin binding	16/3407	46/18639	0.347826086956522	1.90288536389275	0.00573037208127174	0.0405439228976001
GO:0043130	ubiquitin binding	29/3407	100/18639	0.29	1.58653067214558	0.0058129429043611	0.0407955939991765
GO:0050661	NADP binding	18/3407	54/18639	0.333333333333333	1.82359847373055	0.00582794199988235	0.0407955939991765
GO:0008186	ATP-dependent activity, acting on RNA	24/3407	79/18639	0.30379746835443	1.66201379884304	0.00615777114157747	0.0428763323932061
GO:0005543	phospholipid binding	113/3407	497/18639	0.227364185110664	1.24386294284639	0.00639471234674379	0.0442065813370945
GO:0004519	endonuclease activity	35/3407	127/18639	0.275590551181102	1.50769952552526	0.00641600078676675	0.0442065813370945
GO:0043998	histone H2A acetyltransferase activity	10/3407	24/18639	0.416666666666667	2.27949809216319	0.00659871679617512	0.0452287047071169
GO:0008474	palmitoyl-(protein) hydrolase activity	7/3407	14/18639	0.5	2.73539771059583	0.00697544621213013	0.0470753190521193
GO:0098599	palmitoyl hydrolase activity	7/3407	14/18639	0.5	2.73539771059583	0.00697544621213013	0.0470753190521193
GO:0098847	sequence-specific single stranded DNA binding	7/3407	14/18639	0.5	2.73539771059583	0.00697544621213013	0.0470753190521193
GO:0031593	polyubiquitin modification-dependent protein binding	19/3407	59/18639	0.322033898305085	1.76178157631596	0.0071105497463169	0.0477422625824135
GO:0004143	ATP-dependent diacylglycerol kinase activity	6/3407	11/18639	0.545454545454545	2.98407022974091	0.00738762965112235	0.0488226182699908
GO:0032404	mismatch repair complex binding	6/3407	11/18639	0.545454545454545	2.98407022974091	0.00738762965112235	0.0488226182699908
GO:0140031	phosphorylation-dependent protein binding	6/3407	11/18639	0.545454545454545	2.98407022974091	0.00738762965112235	0.0488226182699908
GO:0000149	SNARE binding	30/3407	106/18639	0.283018867924528	1.54833832675236	0.00741985080091046	0.0488226182699908
GO:0036408	histone H3K14 acetyltransferase activity	11/3407	28/18639	0.392857142857143	2.1492410583253	0.00751602097843681	0.0489657604337764
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	11/3407	28/18639	0.392857142857143	2.1492410583253	0.00751602097843681	0.0489657604337764
GO:0051536	iron-sulfur cluster binding	23/3407	76/18639	0.302631578947368	1.65563545641327	0.00760333806255213	0.0492906053710276
GO:0140142	nucleocytoplasmic carrier activity	12/3407	32/18639	0.375	2.05154828294687	0.00818014404384167	0.0527699488318413
GO:0000993	RNA polymerase II complex binding	13/3407	36/18639	0.361111111111111	1.9755650132081	0.0086299744483543	0.0550529429281882
GO:0001098	basal transcription machinery binding	19/3407	60/18639	0.316666666666667	1.73241855004403	0.00865954345450985	0.0550529429281882
GO:0001099	basal RNA polymerase II transcription machinery binding	19/3407	60/18639	0.316666666666667	1.73241855004403	0.00865954345450985	0.0550529429281882
GO:0003724	RNA helicase activity	23/3407	77/18639	0.298701298701299	1.63413369723907	0.00900722920544007	0.0567483520969002
GO:0019205	nucleobase-containing compound kinase activity	15/3407	44/18639	0.340909090909091	1.86504389358807	0.00903603714237411	0.0567483520969002
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	16/3407	48/18639	0.333333333333333	1.82359847373055	0.00905558810056917	0.0567483520969002
GO:0017056	structural constituent of nuclear pore	10/3407	25/18639	0.4	2.18831816847667	0.00922420471496299	0.057531058790954
GO:0071889	14-3-3 protein binding	12/3407	33/18639	0.363636363636364	1.98938015316061	0.0107563710634528	0.0648963087817305
GO:0043021	ribonucleoprotein complex binding	45/3407	177/18639	0.254237288135593	1.39088019182839	0.0108796860808271	0.0648963087817305
GO:0034212	protein N-acetyltransferase activity	17/3407	53/18639	0.320754716981132	1.75478343698601	0.0110259728432319	0.0648963087817305
GO:0032931	histone H3K56 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0043992	histone H3K9 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0043993	histone H3K18 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0043994	histone H3K23 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0043999	histone H2AK5 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0044012	histone H2AK9 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0044014	histone H2BK5 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0044015	histone H2BK12 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0044016	histone H3K4 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0044017	histone H3K27 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0044018	histone H3K36 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0046972	histone H4K16 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0061133	endopeptidase activator activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0140908	histone H3K122 acetyltransferase activity	9/3407	22/18639	0.409090909090909	2.23805267230568	0.0112850780519825	0.0648963087817305
GO:0001727	lipid kinase activity	14/3407	41/18639	0.341463414634146	1.86807648528496	0.0112927467408938	0.0648963087817305
GO:0000340	RNA 7-methylguanosine cap binding	6/3407	12/18639	0.5	2.73539771059583	0.0125108421608313	0.0706620956379999
GO:0005049	nuclear export signal receptor activity	6/3407	12/18639	0.5	2.73539771059583	0.0125108421608313	0.0706620956379999
GO:0043047	single-stranded telomeric DNA binding	6/3407	12/18639	0.5	2.73539771059583	0.0125108421608313	0.0706620956379999
GO:1990817	poly(A) RNA polymerase activity	6/3407	12/18639	0.5	2.73539771059583	0.0125108421608313	0.0706620956379999
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	34/3407	128/18639	0.265625	1.45318003375404	0.0127888085452204	0.071923384809872
GO:0051287	NAD binding	17/3407	54/18639	0.314814814814815	1.72228744741219	0.0134142572847708	0.0739086659127866
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/3407	30/18639	0.366666666666667	2.00595832110361	0.0134226224568055	0.0739086659127866
GO:0043995	histone H4K5 acetyltransferase activity	11/3407	30/18639	0.366666666666667	2.00595832110361	0.0134226224568055	0.0739086659127866
GO:0043996	histone H4K8 acetyltransferase activity	11/3407	30/18639	0.366666666666667	2.00595832110361	0.0134226224568055	0.0739086659127866
GO:0043997	histone H4K12 acetyltransferase activity	11/3407	30/18639	0.366666666666667	2.00595832110361	0.0134226224568055	0.0739086659127866
GO:1990380	K48-linked deubiquitinase activity	8/3407	19/18639	0.421052631578947	2.30349280892281	0.0137356815073248	0.0753173202651642
GO:0043175	RNA polymerase core enzyme binding	14/3407	42/18639	0.333333333333333	1.82359847373055	0.0141525713183316	0.0769619167558861
GO:0048487	beta-tubulin binding	14/3407	42/18639	0.333333333333333	1.82359847373055	0.0141525713183316	0.0769619167558861
GO:0044013	histone H2B acetyltransferase activity	9/3407	23/18639	0.391304347826087	2.14074603437935	0.0155880961384787	0.0844194836141482
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	7/3407	16/18639	0.4375	2.39347299677135	0.0165738735881468	0.0890253781306169
GO:0140328	floppase activity	7/3407	16/18639	0.4375	2.39347299677135	0.0165738735881468	0.0890253781306169
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	10/3407	27/18639	0.37037037037037	2.02622052636728	0.0167708970381713	0.0893542530454797
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	10/3407	27/18639	0.37037037037037	2.02622052636728	0.0167708970381713	0.0893542530454797
GO:0061631	ubiquitin conjugating enzyme activity	12/3407	35/18639	0.342857142857143	1.87570128726571	0.0177335476281251	0.0941022124137608
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	32/3407	122/18639	0.262295081967213	1.43496273342732	0.0184056764847852	0.0972765873653709
GO:0000339	RNA cap binding	8/3407	20/18639	0.4	2.18831816847667	0.0192935685736663	0.101156718099382
GO:0140939	histone H4 methyltransferase activity	8/3407	20/18639	0.4	2.18831816847667	0.0192935685736663	0.101156718099382
GO:0140333	glycerophospholipid flippase activity	6/3407	13/18639	0.461538461538462	2.52498250208846	0.0196899171140401	0.102825122706654
GO:0035035	histone acetyltransferase binding	9/3407	24/18639	0.375	2.05154828294687	0.0209817237438609	0.109138136153838
GO:0043014	alpha-tubulin binding	14/3407	44/18639	0.318181818181818	1.74070763401553	0.0215066344701691	0.111428074656467
GO:0051059	NF-kappaB binding	11/3407	32/18639	0.34375	1.88058592603463	0.0222955316038841	0.114841697176046
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	23/3407	83/18639	0.27710843373494	1.5160035504507	0.0224191193491871	0.114841697176046
GO:0030957	Tat protein binding	5/3407	10/18639	0.5	2.73539771059583	0.0226890891077294	0.114841697176046
GO:0045322	unmethylated CpG binding	5/3407	10/18639	0.5	2.73539771059583	0.0226890891077294	0.114841697176046
GO:0051880	G-quadruplex DNA binding	5/3407	10/18639	0.5	2.73539771059583	0.0226890891077294	0.114841697176046
GO:0098505	G-rich strand telomeric DNA binding	5/3407	10/18639	0.5	2.73539771059583	0.0226890891077294	0.114841697176046
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	7/3407	17/18639	0.411764705882353	2.25268046754951	0.0238135947577385	0.118595378414043
GO:0070403	NAD+ binding	7/3407	17/18639	0.411764705882353	2.25268046754951	0.0238135947577385	0.118595378414043
GO:1990226	histone methyltransferase binding	7/3407	17/18639	0.411764705882353	2.25268046754951	0.0238135947577385	0.118595378414043
GO:0046332	SMAD binding	22/3407	79/18639	0.278481012658228	1.52351264893945	0.0238182222645805	0.118595378414043
GO:0019902	phosphatase binding	46/3407	190/18639	0.242105263157895	1.32450836513061	0.0238812882064753	0.118595378414043
GO:0140296	general transcription initiation factor binding	16/3407	53/18639	0.30188679245283	1.65156088186918	0.0241161098619411	0.119311280369603
GO:0070182	DNA polymerase binding	8/3407	21/18639	0.380952380952381	2.08411254140635	0.026283206218398	0.129545690574576
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/3407	41/18639	0.317073170731707	1.73464245062175	0.0269636416999947	0.132403554019377
GO:0003727	single-stranded RNA binding	24/3407	89/18639	0.269662921348315	1.47527067537753	0.0274652905900323	0.134005357594327
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	9/3407	25/18639	0.36	1.969486351629	0.0275953281976159	0.134005357594327
GO:0017025	TBP-class protein binding	9/3407	25/18639	0.36	1.969486351629	0.0275953281976159	0.134005357594327
GO:0015485	cholesterol binding	16/3407	54/18639	0.296296296296296	1.62097642109383	0.0286221530523286	0.138480711091413
GO:0004722	protein serine/threonine phosphatase activity	27/3407	103/18639	0.262135922330097	1.43409200361335	0.028778841525361	0.138728774532509
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	6/3407	14/18639	0.428571428571429	2.34462660908214	0.0292257702904726	0.139351861240079
GO:0044548	S100 protein binding	6/3407	14/18639	0.428571428571429	2.34462660908214	0.0292257702904726	0.139351861240079
GO:0046030	inositol trisphosphate phosphatase activity	6/3407	14/18639	0.428571428571429	2.34462660908214	0.0292257702904726	0.139351861240079
GO:0019208	phosphatase regulator activity	30/3407	117/18639	0.256410256410256	1.40276805671581	0.0294546921107546	0.139936371183224
GO:0000900	mRNA regulatory element binding translation repressor activity	7/3407	18/18639	0.388888888888889	2.12753155268565	0.0329594320662003	0.156023786327768
GO:0042887	amide transmembrane transporter activity	12/3407	38/18639	0.315789473684211	1.7276196066921	0.0338774124927658	0.159794533478422
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	8/3407	22/18639	0.363636363636364	1.98938015316061	0.0348535651706355	0.163811756301987
GO:0019206	nucleoside kinase activity	5/3407	11/18639	0.454545454545455	2.48672519145076	0.0354403053215686	0.164255491458761
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/3407	11/18639	0.454545454545455	2.48672519145076	0.0354403053215686	0.164255491458761
GO:0031624	ubiquitin conjugating enzyme binding	10/3407	30/18639	0.333333333333333	1.82359847373055	0.035448538743441	0.164255491458761
GO:0004529	DNA exonuclease activity	9/3407	26/18639	0.346153846153846	1.89373687656635	0.035545748609224	0.164255491458761
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	22/3407	82/18639	0.268292682926829	1.46777438129532	0.0355720479223001	0.164255491458761
GO:0003779	actin binding	96/3407	443/18639	0.216704288939052	1.18554483168036	0.0374330022744885	0.172244164311982
GO:0008080	N-acetyltransferase activity	19/3407	69/18639	0.27536231884058	1.50645091308176	0.0379107460053177	0.173834640219506
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/3407	43/18639	0.302325581395349	1.65396140640678	0.0392792565310248	0.179484380537599
GO:0004953	icosanoid receptor activity	6/3407	15/18639	0.4	2.18831816847667	0.041350653825817	0.187001582250087
GO:0050700	CARD domain binding	6/3407	15/18639	0.4	2.18831816847667	0.041350653825817	0.187001582250087
GO:0061578	K63-linked deubiquitinase activity	6/3407	15/18639	0.4	2.18831816847667	0.041350653825817	0.187001582250087
GO:0005164	tumor necrosis factor receptor binding	10/3407	31/18639	0.32258064516129	1.76477271651344	0.0440224299878798	0.19639204429555
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	7/3407	19/18639	0.368421052631579	2.01555620780746	0.0441732865588776	0.19639204429555
GO:0008301	DNA binding, bending	7/3407	19/18639	0.368421052631579	2.01555620780746	0.0441732865588776	0.19639204429555
GO:0042800	histone H3K4 methyltransferase activity	7/3407	19/18639	0.368421052631579	2.01555620780746	0.0441732865588776	0.19639204429555
GO:0050145	nucleoside monophosphate kinase activity	7/3407	19/18639	0.368421052631579	2.01555620780746	0.0441732865588776	0.19639204429555
GO:0004860	protein kinase inhibitor activity	22/3407	84/18639	0.261904761904762	1.43282737221686	0.0455076896737691	0.20164350037266
GO:0016757	glycosyltransferase activity	60/3407	267/18639	0.224719101123595	1.22939222948127	0.0466708433805694	0.206103456002783
GO:0031072	heat shock protein binding	32/3407	131/18639	0.244274809160305	1.33637750746667	0.0469617572465949	0.206694556978324
GO:0044325	transmembrane transporter binding	33/3407	136/18639	0.242647058823529	1.32747241837739	0.0480472165076484	0.210767123080218
GO:0051015	actin filament binding	48/3407	209/18639	0.229665071770335	1.2564506230488	0.0500878281825808	0.218567747353453
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	52/3407	229/18639	0.22707423580786	1.24227668952824	0.0514134487060175	0.218567747353453
GO:1901981	phosphatidylinositol phosphate binding	43/3407	185/18639	0.232432432432432	1.27159028708779	0.0515552083155232	0.218567747353453
GO:0044390	ubiquitin-like protein conjugating enzyme binding	11/3407	36/18639	0.305555555555556	1.67163193425301	0.0516380849426655	0.218567747353453
GO:0005078	MAP-kinase scaffold activity	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0016273	arginine N-methyltransferase activity	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0016274	protein-arginine N-methyltransferase activity	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0070679	inositol 1,4,5 trisphosphate binding	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0097677	STAT family protein binding	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/3407	12/18639	0.416666666666667	2.27949809216319	0.0518184932935238	0.218567747353453
GO:0019210	kinase inhibitor activity	23/3407	90/18639	0.255555555555556	1.39809216319343	0.0533762849948888	0.224419140745283
GO:0033192	calmodulin-dependent protein phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:0140791	histone H2AXS140 phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:1990439	MAP kinase serine/threonine phosphatase activity	21/3407	81/18639	0.259259259259259	1.4183543684571	0.0549118535123468	0.224866887873677
GO:0140303	intramembrane lipid transporter activity	13/3407	45/18639	0.288888888888889	1.58045201056648	0.0551097414748352	0.224866887873677
GO:0019789	SUMO transferase activity	9/3407	28/18639	0.321428571428571	1.75846995681161	0.0558377068110944	0.224866887873677
GO:0046875	ephrin receptor binding	9/3407	28/18639	0.321428571428571	1.75846995681161	0.0558377068110944	0.224866887873677
GO:0046966	nuclear thyroid hormone receptor binding	9/3407	28/18639	0.321428571428571	1.75846995681161	0.0558377068110944	0.224866887873677
GO:0004708	MAP kinase kinase activity	6/3407	16/18639	0.375	2.05154828294687	0.0562167219684192	0.224866887873677
GO:0043023	ribosomal large subunit binding	6/3407	16/18639	0.375	2.05154828294687	0.0562167219684192	0.224866887873677
GO:0097027	ubiquitin-protein transferase activator activity	6/3407	16/18639	0.375	2.05154828294687	0.0562167219684192	0.224866887873677
GO:0140327	flippase activity	6/3407	16/18639	0.375	2.05154828294687	0.0562167219684192	0.224866887873677
GO:0016505	peptidase activator activity involved in apoptotic process	7/3407	20/18639	0.35	1.91477839741708	0.0575700577816836	0.228888809790621
GO:0140664	ATP-dependent DNA damage sensor activity	7/3407	20/18639	0.35	1.91477839741708	0.0575700577816836	0.228888809790621
GO:0042169	SH2 domain binding	12/3407	41/18639	0.292682926829268	1.60120841595854	0.0584235343459366	0.231582443371243
GO:0032934	sterol binding	18/3407	68/18639	0.264705882352941	1.44815172913897	0.0601942737663171	0.237884877707127
GO:0033549	MAP kinase phosphatase activity	21/3407	82/18639	0.25609756097561	1.40105736396372	0.0615698193712153	0.242592461953651
GO:0004521	RNA endonuclease activity	19/3407	73/18639	0.26027397260274	1.42390565757043	0.0633282466481866	0.248474221996471
GO:0019903	protein phosphatase binding	34/3407	144/18639	0.236111111111111	1.29171558555914	0.0634402268927159	0.248474221996471
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	9/3407	29/18639	0.310344827586207	1.69783306174914	0.0683167198845337	0.265990542509013
GO:0097472	cyclin-dependent protein kinase activity	9/3407	29/18639	0.310344827586207	1.69783306174914	0.0683167198845337	0.265990542509013
GO:0035198	miRNA binding	12/3407	42/18639	0.285714285714286	1.56308440605476	0.0687103339565667	0.266733921790094
GO:0008139	nuclear localization sequence binding	8/3407	25/18639	0.32	1.75065453478133	0.0711343471860455	0.273721640049228
GO:0019211	phosphatase activator activity	8/3407	25/18639	0.32	1.75065453478133	0.0711343471860455	0.273721640049228
GO:0042974	nuclear retinoic acid receptor binding	8/3407	25/18639	0.32	1.75065453478133	0.0711343471860455	0.273721640049228
GO:0004535	poly(A)-specific ribonuclease activity	5/3407	13/18639	0.384615384615385	2.10415208507372	0.0718988534057013	0.274257655309864
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/3407	13/18639	0.384615384615385	2.10415208507372	0.0718988534057013	0.274257655309864
GO:0035673	oligopeptide transmembrane transporter activity	5/3407	13/18639	0.384615384615385	2.10415208507372	0.0718988534057013	0.274257655309864
GO:0043022	ribosome binding	27/3407	112/18639	0.241071428571429	1.3188524676087	0.0731579366970589	0.277662663888581
GO:0072542	protein phosphatase activator activity	7/3407	21/18639	0.333333333333333	1.82359847373055	0.0732134835633265	0.277662663888581
GO:0005092	GDP-dissociation inhibitor activity	6/3407	17/18639	0.352941176470588	1.93086897218529	0.0738911549924268	0.277830742771525
GO:0032183	SUMO binding	6/3407	17/18639	0.352941176470588	1.93086897218529	0.0738911549924268	0.277830742771525
GO:0046965	nuclear retinoid X receptor binding	6/3407	17/18639	0.352941176470588	1.93086897218529	0.0738911549924268	0.277830742771525
GO:0017018	myosin phosphatase activity	21/3407	84/18639	0.25	1.36769885529792	0.0765224849288452	0.286904815288776
GO:0008175	tRNA methyltransferase activity	10/3407	34/18639	0.294117647058824	1.60905747682108	0.077754209747213	0.28987121820774
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	10/3407	34/18639	0.294117647058824	1.60905747682108	0.077754209747213	0.28987121820774
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	16/3407	61/18639	0.262295081967213	1.43496273342732	0.0787398804509971	0.291892063869048
GO:0019905	syntaxin binding	16/3407	61/18639	0.262295081967213	1.43496273342732	0.0787398804509971	0.291892063869048
GO:0019003	GDP binding	19/3407	75/18639	0.253333333333333	1.38593484003522	0.0796450723049371	0.294418300992408
GO:0016410	N-acyltransferase activity	23/3407	94/18639	0.24468085106383	1.33859887965328	0.0808875631097851	0.298173762051757
GO:0031490	chromatin DNA binding	30/3407	128/18639	0.234375	1.2822176768418	0.0836253442535603	0.307404896753311
GO:0016504	peptidase activator activity	15/3407	57/18639	0.263157894736842	1.43968300557675	0.0847726242839406	0.31075424389322
GO:0043548	phosphatidylinositol 3-kinase binding	8/3407	26/18639	0.307692307692308	1.68332166805897	0.0869515021090774	0.316099935844049
GO:0050681	nuclear androgen receptor binding	8/3407	26/18639	0.307692307692308	1.68332166805897	0.0869515021090774	0.316099935844049
GO:0052742	phosphatidylinositol kinase activity	8/3407	26/18639	0.307692307692308	1.68332166805897	0.0869515021090774	0.316099935844049
GO:0070034	telomerase RNA binding	7/3407	22/18639	0.318181818181818	1.74070763401553	0.091114778813249	0.325508409251642
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0003680	minor groove of adenine-thymine-rich DNA binding	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0004955	prostaglandin receptor activity	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0032356	oxidized DNA binding	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0042975	peroxisome proliferator activated receptor binding	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0051864	histone H3K36 demethylase activity	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0070513	death domain binding	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:1990757	ubiquitin ligase activator activity	4/3407	10/18639	0.4	2.18831816847667	0.0924929112786406	0.325508409251642
GO:0008173	RNA methyltransferase activity	17/3407	67/18639	0.253731343283582	1.38811227104863	0.0925077090122448	0.325508409251642
GO:0035401	histone H3Y41 kinase activity	27/3407	115/18639	0.234782608695652	1.28444762062761	0.0950717722334935	0.331099095507406
GO:0140801	histone H2AXY142 kinase activity	27/3407	115/18639	0.234782608695652	1.28444762062761	0.0950717722334935	0.331099095507406
GO:0008174	mRNA methyltransferase activity	5/3407	14/18639	0.357142857142857	1.95385550756845	0.0956061218030505	0.331099095507406
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	5/3407	14/18639	0.357142857142857	1.95385550756845	0.0956061218030505	0.331099095507406
GO:0034236	protein kinase A catalytic subunit binding	5/3407	14/18639	0.357142857142857	1.95385550756845	0.0956061218030505	0.331099095507406
GO:0061665	SUMO ligase activity	5/3407	14/18639	0.357142857142857	1.95385550756845	0.0956061218030505	0.331099095507406
GO:0061980	regulatory RNA binding	15/3407	58/18639	0.258620689655172	1.41486088479095	0.0958691902921034	0.331138725523381
GO:0072349	modified amino acid transmembrane transporter activity	9/3407	31/18639	0.290322580645161	1.5882954448621	0.0981042595573313	0.33797174234934
GO:0060590	ATPase regulator activity	13/3407	49/18639	0.26530612244898	1.45143551990799	0.0984709151625607	0.338349149749164
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	11/3407	40/18639	0.275	1.50446874082771	0.0996443175827076	0.341489380049071
GO:0046915	transition metal ion transmembrane transporter activity	12/3407	45/18639	0.266666666666667	1.45887877898444	0.106256041488635	0.363202469088424
GO:0019888	protein phosphatase regulator activity	25/3407	107/18639	0.233644859813084	1.27822322925039	0.109686039895034	0.373955514253535
GO:0043274	phospholipase binding	7/3407	23/18639	0.304347826086957	1.66502469340616	0.111233783674389	0.378252349652445
GO:0017080	sodium channel regulator activity	11/3407	41/18639	0.268292682926829	1.46777438129532	0.114758604769524	0.389232793496631
GO:0016874	ligase activity	37/3407	167/18639	0.221556886227545	1.21209239870714	0.116278371491325	0.39337361666474
GO:0008574	plus-end-directed microtubule motor activity	6/3407	19/18639	0.315789473684211	1.7276196066921	0.117518737946307	0.396550408044463
GO:0030291	protein serine/threonine kinase inhibitor activity	12/3407	46/18639	0.260869565217391	1.42716402291956	0.121011704869796	0.407292592349494
GO:0000774	adenyl-nucleotide exchange factor activity	5/3407	15/18639	0.333333333333333	1.82359847373055	0.122733855791667	0.412035087300598
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	21/3407	89/18639	0.235955056179775	1.29086184095534	0.123906605988058	0.412592057449647
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	21/3407	89/18639	0.235955056179775	1.29086184095534	0.123906605988058	0.412592057449647
GO:0000099	sulfur amino acid transmembrane transporter activity	4/3407	11/18639	0.363636363636364	1.98938015316061	0.125094400396968	0.412592057449647
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	4/3407	11/18639	0.363636363636364	1.98938015316061	0.125094400396968	0.412592057449647
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/3407	11/18639	0.363636363636364	1.98938015316061	0.125094400396968	0.412592057449647
GO:0004954	prostanoid receptor activity	4/3407	11/18639	0.363636363636364	1.98938015316061	0.125094400396968	0.412592057449647
GO:0032794	GTPase activating protein binding	4/3407	11/18639	0.363636363636364	1.98938015316061	0.125094400396968	0.412592057449647
GO:0031492	nucleosomal DNA binding	11/3407	42/18639	0.261904761904762	1.43282737221686	0.13109831376767	0.431313452295633
GO:0070300	phosphatidic acid binding	7/3407	24/18639	0.291666666666667	1.59564866451424	0.133482222377477	0.436971653355123
GO:0140612	DNA damage sensor activity	7/3407	24/18639	0.291666666666667	1.59564866451424	0.133482222377477	0.436971653355123
GO:0030296	protein tyrosine kinase activator activity	9/3407	33/18639	0.272727272727273	1.49203511487045	0.134254297436108	0.43840857425786
GO:0140793	histone H2AXY142 phosphatase activity	21/3407	90/18639	0.233333333333333	1.27651893161139	0.135124853529826	0.440159176349632
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/3407	20/18639	0.3	1.6412386263575	0.143211029445432	0.463060724201937
GO:0016004	phospholipase activator activity	6/3407	20/18639	0.3	1.6412386263575	0.143211029445432	0.463060724201937
GO:0061608	nuclear import signal receptor activity	6/3407	20/18639	0.3	1.6412386263575	0.143211029445432	0.463060724201937
GO:0016417	S-acyltransferase activity	8/3407	29/18639	0.275862068965517	1.50918494377701	0.145441527731683	0.469120221801211
GO:0004712	protein serine/threonine/tyrosine kinase activity	11/3407	43/18639	0.255813953488372	1.39950580542112	0.14862794975095	0.47822587254829
GO:0004707	MAP kinase activity	5/3407	16/18639	0.3125	1.7096235691224	0.152968916620416	0.485077335596309
GO:0005159	insulin-like growth factor receptor binding	5/3407	16/18639	0.3125	1.7096235691224	0.152968916620416	0.485077335596309
GO:0005521	lamin binding	5/3407	16/18639	0.3125	1.7096235691224	0.152968916620416	0.485077335596309
GO:0008296	3'-5'-DNA exonuclease activity	5/3407	16/18639	0.3125	1.7096235691224	0.152968916620416	0.485077335596309
GO:0015923	mannosidase activity	5/3407	16/18639	0.3125	1.7096235691224	0.152968916620416	0.485077335596309
GO:0070411	I-SMAD binding	5/3407	16/18639	0.3125	1.7096235691224	0.152968916620416	0.485077335596309
GO:0140693	molecular condensate scaffold activity	12/3407	48/18639	0.25	1.36769885529792	0.153780338775271	0.485551639545127
GO:0008376	acetylgalactosaminyltransferase activity	9/3407	34/18639	0.264705882352941	1.44815172913897	0.15459432900411	0.485551639545127
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	9/3407	34/18639	0.264705882352941	1.44815172913897	0.15459432900411	0.485551639545127
GO:0030332	cyclin binding	9/3407	34/18639	0.264705882352941	1.44815172913897	0.15459432900411	0.485551639545127
GO:0000030	mannosyltransferase activity	7/3407	25/18639	0.28	1.53182271793367	0.157728618285255	0.491419941451595
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/3407	25/18639	0.28	1.53182271793367	0.157728618285255	0.491419941451595
GO:0019707	protein-cysteine S-acyltransferase activity	7/3407	25/18639	0.28	1.53182271793367	0.157728618285255	0.491419941451595
GO:0016251	RNA polymerase II general transcription initiation factor activity	13/3407	53/18639	0.245283018867925	1.34189321651871	0.157956409752298	0.491419941451595
GO:0016776	phosphotransferase activity, phosphate group as acceptor	10/3407	39/18639	0.256410256410256	1.40276805671581	0.161708777559362	0.496130018173602
GO:0004126	cytidine deaminase activity	4/3407	12/18639	0.333333333333333	1.82359847373055	0.161732353948689	0.496130018173602
GO:0004300	enoyl-CoA hydratase activity	4/3407	12/18639	0.333333333333333	1.82359847373055	0.161732353948689	0.496130018173602
GO:0005095	GTPase inhibitor activity	4/3407	12/18639	0.333333333333333	1.82359847373055	0.161732353948689	0.496130018173602
GO:0017166	vinculin binding	4/3407	12/18639	0.333333333333333	1.82359847373055	0.161732353948689	0.496130018173602
GO:0034452	dynactin binding	4/3407	12/18639	0.333333333333333	1.82359847373055	0.161732353948689	0.496130018173602
GO:0003777	microtubule motor activity	16/3407	68/18639	0.235294117647059	1.28724598145686	0.166336831303601	0.508463062695511
GO:0001046	core promoter sequence-specific DNA binding	11/3407	44/18639	0.25	1.36769885529792	0.167298256950727	0.508463062695511
GO:0001223	transcription coactivator binding	11/3407	44/18639	0.25	1.36769885529792	0.167298256950727	0.508463062695511
GO:0016790	thiolester hydrolase activity	11/3407	44/18639	0.25	1.36769885529792	0.167298256950727	0.508463062695511
GO:0001968	fibronectin binding	8/3407	30/18639	0.266666666666667	1.45887877898444	0.168364598459306	0.509351290971143
GO:0032452	histone demethylase activity	8/3407	30/18639	0.266666666666667	1.45887877898444	0.168364598459306	0.509351290971143
GO:0140312	cargo adaptor activity	6/3407	21/18639	0.285714285714286	1.56308440605476	0.171210047798274	0.516771612161763
GO:0004725	protein tyrosine phosphatase activity	22/3407	98/18639	0.224489795918367	1.22813774761446	0.172608035955635	0.519799028186763
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	13/3407	54/18639	0.240740740740741	1.31704334213873	0.175223875870162	0.526471736632724
GO:0004177	aminopeptidase activity	10/3407	40/18639	0.25	1.36769885529792	0.182396930884913	0.544295603275613
GO:0015036	disulfide oxidoreductase activity	10/3407	40/18639	0.25	1.36769885529792	0.182396930884913	0.544295603275613
GO:0032451	demethylase activity	10/3407	40/18639	0.25	1.36769885529792	0.182396930884913	0.544295603275613
GO:0004435	phosphatidylinositol phospholipase C activity	7/3407	26/18639	0.269230769230769	1.4729064595516	0.183804397929111	0.544691692671479
GO:0008198	ferrous iron binding	7/3407	26/18639	0.269230769230769	1.4729064595516	0.183804397929111	0.544691692671479
GO:0070412	R-SMAD binding	7/3407	26/18639	0.269230769230769	1.4729064595516	0.183804397929111	0.544691692671479
GO:0016835	carbon-oxygen lyase activity	18/3407	79/18639	0.227848101265823	1.24651034913228	0.184185260819763	0.544691692671479
GO:0051117	ATPase binding	19/3407	84/18639	0.226190476190476	1.23744182146002	0.184884303373042	0.545533056589515
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/3407	17/18639	0.294117647058824	1.60905747682108	0.185917983965412	0.547355854359021
GO:0032813	tumor necrosis factor receptor superfamily binding	12/3407	50/18639	0.24	1.312990901086	0.190625087405687	0.559961194254205
GO:0070273	phosphatidylinositol-4-phosphate binding	8/3407	31/18639	0.258064516129032	1.41181817321075	0.19280297720782	0.563841595567757
GO:0140457	protein demethylase activity	8/3407	31/18639	0.258064516129032	1.41181817321075	0.19280297720782	0.563841595567757
GO:0140313	molecular sequestering activity	13/3407	55/18639	0.236363636363636	1.29309709955439	0.193370543306791	0.564247527697863
GO:0016409	palmitoyltransferase activity	9/3407	36/18639	0.25	1.36769885529792	0.199369682146855	0.573180116877026
GO:0055106	ubiquitin-protein transferase regulator activity	9/3407	36/18639	0.25	1.36769885529792	0.199369682146855	0.573180116877026
GO:0004407	histone deacetylase activity	6/3407	22/18639	0.272727272727273	1.49203511487045	0.201245773667659	0.573180116877026
GO:0008970	phospholipase A1 activity	6/3407	22/18639	0.272727272727273	1.49203511487045	0.201245773667659	0.573180116877026
GO:0033558	protein lysine deacetylase activity	6/3407	22/18639	0.272727272727273	1.49203511487045	0.201245773667659	0.573180116877026
GO:0034062	5'-3' RNA polymerase activity	6/3407	22/18639	0.272727272727273	1.49203511487045	0.201245773667659	0.573180116877026
GO:0097747	RNA polymerase activity	6/3407	22/18639	0.272727272727273	1.49203511487045	0.201245773667659	0.573180116877026
GO:0005035	death receptor activity	4/3407	13/18639	0.307692307692308	1.68332166805897	0.201658354190017	0.573180116877026
GO:0008253	5'-nucleotidase activity	4/3407	13/18639	0.307692307692308	1.68332166805897	0.201658354190017	0.573180116877026
GO:0019104	DNA N-glycosylase activity	4/3407	13/18639	0.307692307692308	1.68332166805897	0.201658354190017	0.573180116877026
GO:0043560	insulin receptor substrate binding	4/3407	13/18639	0.307692307692308	1.68332166805897	0.201658354190017	0.573180116877026
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/3407	13/18639	0.307692307692308	1.68332166805897	0.201658354190017	0.573180116877026
GO:0005048	signal sequence binding	12/3407	51/18639	0.235294117647059	1.28724598145686	0.210437344028461	0.595560311271946
GO:0030544	Hsp70 protein binding	12/3407	51/18639	0.235294117647059	1.28724598145686	0.210437344028461	0.595560311271946
GO:0001671	ATPase activator activity	7/3407	27/18639	0.259259259259259	1.4183543684571	0.21151073685559	0.596034538976352
GO:0005385	zinc ion transmembrane transporter activity	7/3407	27/18639	0.259259259259259	1.4183543684571	0.21151073685559	0.596034538976352
GO:0016836	hydro-lyase activity	14/3407	61/18639	0.229508196721311	1.25559239174891	0.213674096844921	0.600844255230591
GO:0022884	macromolecule transmembrane transporter activity	8/3407	32/18639	0.25	1.36769885529792	0.218603220772349	0.610950277056354
GO:0008409	5'-3' exonuclease activity	5/3407	18/18639	0.277777777777778	1.51966539477546	0.221133740699978	0.610950277056354
GO:0008525	phosphatidylcholine transporter activity	5/3407	18/18639	0.277777777777778	1.51966539477546	0.221133740699978	0.610950277056354
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	5/3407	18/18639	0.277777777777778	1.51966539477546	0.221133740699978	0.610950277056354
GO:0017075	syntaxin-1 binding	5/3407	18/18639	0.277777777777778	1.51966539477546	0.221133740699978	0.610950277056354
GO:0035615	clathrin adaptor activity	5/3407	18/18639	0.277777777777778	1.51966539477546	0.221133740699978	0.610950277056354
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	5/3407	18/18639	0.277777777777778	1.51966539477546	0.221133740699978	0.610950277056354
GO:0050811	GABA receptor binding	5/3407	18/18639	0.277777777777778	1.51966539477546	0.221133740699978	0.610950277056354
GO:0042826	histone deacetylase binding	27/3407	127/18639	0.21259842519685	1.16308249111949	0.221446263036384	0.610950277056354
GO:0005158	insulin receptor binding	6/3407	23/18639	0.260869565217391	1.42716402291956	0.233014711312342	0.638848666848004
GO:0042171	lysophosphatidic acid acyltransferase activity	6/3407	23/18639	0.260869565217391	1.42716402291956	0.233014711312342	0.638848666848004
GO:0071617	lysophospholipid acyltransferase activity	6/3407	23/18639	0.260869565217391	1.42716402291956	0.233014711312342	0.638848666848004
GO:0097718	disordered domain specific binding	7/3407	28/18639	0.25	1.36769885529792	0.24062574291732	0.651538112053879
GO:0141052	histone H3 demethylase activity	7/3407	28/18639	0.25	1.36769885529792	0.24062574291732	0.651538112053879
GO:0005496	steroid binding	23/3407	108/18639	0.212962962962963	1.16507680266119	0.241176459759186	0.651538112053879
GO:0004705	JUN kinase activity	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0005545	1-phosphatidylinositol binding	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0008195	phosphatidate phosphatase activity	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0008559	ABC-type xenobiotic transporter activity	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0016530	metallochaperone activity	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0019992	diacylglycerol binding	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0030983	mismatched DNA binding	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0032454	histone H3K9 demethylase activity	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0070742	C2H2 zinc finger domain binding	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0071933	Arp2/3 complex binding	4/3407	14/18639	0.285714285714286	1.56308440605476	0.244079247144804	0.651538112053879
GO:0140311	protein sequestering activity	8/3407	33/18639	0.242424242424242	1.3262534354404	0.245594876239946	0.654074432027499
GO:0051087	protein-folding chaperone binding	28/3407	134/18639	0.208955223880597	1.14315128204005	0.246023437578733	0.654074432027499
GO:0032266	phosphatidylinositol-3-phosphate binding	11/3407	48/18639	0.229166666666667	1.25372395068976	0.251980844398794	0.668558508322616
GO:0016860	intramolecular oxidoreductase activity	12/3407	53/18639	0.226415094339623	1.23867066140189	0.252487521760137	0.668558508322616
GO:0042577	lipid phosphatase activity	5/3407	19/18639	0.263157894736842	1.43968300557675	0.258139098826289	0.681682035393041
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/3407	24/18639	0.25	1.36769885529792	0.266192207623964	0.681682035393041
GO:0060229	lipase activator activity	6/3407	24/18639	0.25	1.36769885529792	0.266192207623964	0.681682035393041
GO:0004090	carbonyl reductase (NADPH) activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0005031	tumor necrosis factor receptor activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0005131	growth hormone receptor binding	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0005522	profilin binding	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0016783	sulfurtransferase activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0031419	cobalamin binding	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0043422	protein kinase B binding	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0140940	histone H2A methyltransferase activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0140999	histone H3K4 trimethyltransferase activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:1990259	histone H2AQ104 methyltransferase activity	3/3407	10/18639	0.3	1.6412386263575	0.270910402696182	0.681682035393041
GO:0004629	phospholipase C activity	7/3407	29/18639	0.241379310344828	1.32053682580488	0.270911629567295	0.681682035393041
GO:0106222	lncRNA binding	7/3407	29/18639	0.241379310344828	1.32053682580488	0.270911629567295	0.681682035393041
GO:0015035	protein-disulfide reductase activity	8/3407	34/18639	0.235294117647059	1.28724598145686	0.273595044620203	0.687120379236999
GO:0003925	G protein activity	12/3407	54/18639	0.222222222222222	1.21573231582037	0.274562849157272	0.688237541887562
GO:0004559	alpha-mannosidase activity	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0008252	nucleotidase activity	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0017081	chloride channel regulator activity	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0120283	protein serine/threonine kinase binding	4/3407	15/18639	0.266666666666667	1.45887877898444	0.28820484400049	0.711590196443987
GO:0016829	lyase activity	40/3407	200/18639	0.2	1.09415908423833	0.289610858954501	0.713722641168771
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	13/3407	60/18639	0.216666666666667	1.18533900792486	0.295173446327782	0.723796228491897
GO:0015095	magnesium ion transmembrane transporter activity	5/3407	20/18639	0.25	1.36769885529792	0.296448455286575	0.723796228491897
GO:0030742	GTP-dependent protein binding	5/3407	20/18639	0.25	1.36769885529792	0.296448455286575	0.723796228491897
GO:0042288	MHC class I protein binding	5/3407	20/18639	0.25	1.36769885529792	0.296448455286575	0.723796228491897
GO:0043024	ribosomal small subunit binding	5/3407	20/18639	0.25	1.36769885529792	0.296448455286575	0.723796228491897
GO:0015605	organophosphate ester transmembrane transporter activity	11/3407	50/18639	0.22	1.20357499266217	0.299073273024284	0.728852643148071
GO:0120020	cholesterol transfer activity	6/3407	25/18639	0.24	1.312990901086	0.300443867415135	0.730839426096705
GO:0031210	phosphatidylcholine binding	7/3407	30/18639	0.233333333333333	1.27651893161139	0.302121595556683	0.733564612089659
GO:0015101	organic cation transmembrane transporter activity	17/3407	81/18639	0.209876543209877	1.14819163160813	0.304748274747986	0.738579612464733
GO:0016758	hexosyltransferase activity	39/3407	197/18639	0.197969543147208	1.08305087018515	0.316857732832264	0.75569362801206
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0002162	dystroglycan binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0005225	volume-sensitive anion channel activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0008172	S-methyltransferase activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0008432	JUN kinase binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0015217	ADP transmembrane transporter activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0019107	myristoyltransferase activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0019215	intermediate filament binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0032050	clathrin heavy chain binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0035252	UDP-xylosyltransferase activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0042285	xylosyltransferase activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0042608	T cell receptor binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0045294	alpha-catenin binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0050786	RAGE receptor binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0070990	snRNP binding	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0097493	structural molecule activity conferring elasticity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0180030	inositol phosphate kinase activity	3/3407	11/18639	0.272727272727273	1.49203511487045	0.325591403558387	0.75569362801206
GO:0015175	neutral L-amino acid transmembrane transporter activity	9/3407	41/18639	0.219512195121951	1.2009063119689	0.329274420000202	0.761555600562858
GO:0016877	ligase activity, forming carbon-sulfur bonds	9/3407	41/18639	0.219512195121951	1.2009063119689	0.329274420000202	0.761555600562858
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/3407	16/18639	0.25	1.36769885529792	0.333283486460515	0.764066543662105
GO:0015562	efflux transmembrane transporter activity	4/3407	16/18639	0.25	1.36769885529792	0.333283486460515	0.764066543662105
GO:0022858	alanine transmembrane transporter activity	4/3407	16/18639	0.25	1.36769885529792	0.333283486460515	0.764066543662105
GO:0070006	metalloaminopeptidase activity	6/3407	26/18639	0.230769230769231	1.26249125104423	0.335435708260941	0.764066543662105
GO:0097602	cullin family protein binding	6/3407	26/18639	0.230769230769231	1.26249125104423	0.335435708260941	0.764066543662105
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/3407	21/18639	0.238095238095238	1.30257033837897	0.335585457626669	0.764066543662105
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/3407	21/18639	0.238095238095238	1.30257033837897	0.335585457626669	0.764066543662105
GO:0008373	sialyltransferase activity	5/3407	21/18639	0.238095238095238	1.30257033837897	0.335585457626669	0.764066543662105
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/3407	21/18639	0.238095238095238	1.30257033837897	0.335585457626669	0.764066543662105
GO:0004620	phospholipase activity	22/3407	109/18639	0.201834862385321	1.10419724097446	0.33963164482935	0.771943427625949
GO:0030159	signaling receptor complex adaptor activity	11/3407	52/18639	0.211538461538462	1.15728364679054	0.348228712673602	0.790118941169759
GO:0002020	protease binding	27/3407	136/18639	0.198529411764706	1.08611379685423	0.35002250867149	0.792822067834219
GO:0140359	ABC-type transporter activity	10/3407	47/18639	0.212765957446809	1.16399902578546	0.352643951015192	0.797387353154627
GO:0005548	phospholipid transporter activity	14/3407	68/18639	0.205882352941176	1.12634023377475	0.35739516973866	0.80314252035039
GO:0140223	general transcription initiation factor activity	14/3407	68/18639	0.205882352941176	1.12634023377475	0.35739516973866	0.80314252035039
GO:1990841	promoter-specific chromatin binding	14/3407	68/18639	0.205882352941176	1.12634023377475	0.35739516973866	0.80314252035039
GO:0008378	galactosyltransferase activity	7/3407	32/18639	0.21875	1.19673649838568	0.366319024679872	0.80314252035039
GO:0030515	snoRNA binding	7/3407	32/18639	0.21875	1.19673649838568	0.366319024679872	0.80314252035039
GO:0120015	sterol transfer activity	7/3407	32/18639	0.21875	1.19673649838568	0.366319024679872	0.80314252035039
GO:0003774	cytoskeletal motor activity	30/3407	153/18639	0.196078431372549	1.07270498454739	0.366374429250734	0.80314252035039
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/3407	27/18639	0.222222222222222	1.21573231582037	0.370842842948185	0.80314252035039
GO:0008266	poly(U) RNA binding	6/3407	27/18639	0.222222222222222	1.21573231582037	0.370842842948185	0.80314252035039
GO:0008320	protein transmembrane transporter activity	6/3407	27/18639	0.222222222222222	1.21573231582037	0.370842842948185	0.80314252035039
GO:0015252	proton channel activity	6/3407	27/18639	0.222222222222222	1.21573231582037	0.370842842948185	0.80314252035039
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	6/3407	27/18639	0.222222222222222	1.21573231582037	0.370842842948185	0.80314252035039
GO:0016853	isomerase activity	35/3407	180/18639	0.194444444444444	1.06376577634282	0.371567431609623	0.80314252035039
GO:0051018	protein kinase A binding	11/3407	53/18639	0.207547169811321	1.13544810628506	0.373303786484272	0.80314252035039
GO:0031683	G-protein beta/gamma-subunit complex binding	5/3407	22/18639	0.227272727272727	1.24336259572538	0.375097129379319	0.80314252035039
GO:0140517	protein-RNA adaptor activity	5/3407	22/18639	0.227272727272727	1.24336259572538	0.375097129379319	0.80314252035039
GO:0004550	nucleoside diphosphate kinase activity	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0008429	phosphatidylethanolamine binding	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0015278	intracellularly gated calcium channel activity	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0017110	nucleoside diphosphate phosphatase activity	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0019198	transmembrane receptor protein phosphatase activity	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0030169	low-density lipoprotein particle binding	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0031489	myosin V binding	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0038191	neuropilin binding	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0051787	misfolded protein binding	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0070402	NADPH binding	4/3407	17/18639	0.235294117647059	1.28724598145686	0.378626717997469	0.80314252035039
GO:0003995	acyl-CoA dehydrogenase activity	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0004526	ribonuclease P activity	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0008603	cAMP-dependent protein kinase regulator activity	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0016423	tRNA (guanine) methyltransferase activity	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0035197	siRNA binding	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0035259	nuclear glucocorticoid receptor binding	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0035497	cAMP response element binding	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0036009	protein-glutamine N-methyltransferase activity	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0045295	gamma-catenin binding	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:1990459	transferrin receptor binding	3/3407	12/18639	0.25	1.36769885529792	0.380211086761621	0.80314252035039
GO:1990782	protein tyrosine kinase binding	23/3407	117/18639	0.196581196581197	1.07545551014879	0.385774352260681	0.813588217267718
GO:0043531	ADP binding	8/3407	38/18639	0.210526315789474	1.1517464044614	0.391831371462762	0.825040135751992
GO:0070851	growth factor receptor binding	27/3407	139/18639	0.194244604316547	1.06267249188615	0.396614676280612	0.831773900028961
GO:0140101	catalytic activity, acting on a tRNA	27/3407	139/18639	0.194244604316547	1.06267249188615	0.396614676280612	0.831773900028961
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/3407	33/18639	0.212121212121212	1.16047175601035	0.398821680029084	0.831773900028961
GO:0019239	deaminase activity	7/3407	33/18639	0.212121212121212	1.16047175601035	0.398821680029084	0.831773900028961
GO:0019956	chemokine binding	7/3407	33/18639	0.212121212121212	1.16047175601035	0.398821680029084	0.831773900028961
GO:0140416	transcription regulator inhibitor activity	7/3407	33/18639	0.212121212121212	1.16047175601035	0.398821680029084	0.831773900028961
GO:0097110	scaffold protein binding	14/3407	70/18639	0.2	1.09415908423833	0.401598162636414	0.836239212072026
GO:0035254	glutamate receptor binding	10/3407	49/18639	0.204081632653061	1.11648886146769	0.405780285830507	0.842150050886153
GO:0045499	chemorepellent activity	6/3407	28/18639	0.214285714285714	1.17231330454107	0.406356597502057	0.842150050886153
GO:0051537	2 iron, 2 sulfur cluster binding	6/3407	28/18639	0.214285714285714	1.17231330454107	0.406356597502057	0.842150050886153
GO:0016248	channel inhibitor activity	9/3407	44/18639	0.204545454545455	1.11902633615284	0.413549430472096	0.855120438141591
GO:0008171	O-methyltransferase activity	5/3407	23/18639	0.217391304347826	1.18930335243297	0.414564467731258	0.855120438141591
GO:0140103	catalytic activity, acting on a glycoprotein	5/3407	23/18639	0.217391304347826	1.18930335243297	0.414564467731258	0.855120438141591
GO:0008081	phosphoric diester hydrolase activity	17/3407	87/18639	0.195402298850575	1.06900600184205	0.422939867072424	0.8629878023971
GO:0004706	JUN kinase kinase kinase activity	4/3407	18/18639	0.222222222222222	1.21573231582037	0.423624711511039	0.8629878023971
GO:0015172	acidic amino acid transmembrane transporter activity	4/3407	18/18639	0.222222222222222	1.21573231582037	0.423624711511039	0.8629878023971
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/3407	18/18639	0.222222222222222	1.21573231582037	0.423624711511039	0.8629878023971
GO:0030228	lipoprotein particle receptor activity	4/3407	18/18639	0.222222222222222	1.21573231582037	0.423624711511039	0.8629878023971
GO:0070628	proteasome binding	4/3407	18/18639	0.222222222222222	1.21573231582037	0.423624711511039	0.8629878023971
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3407	18/18639	0.222222222222222	1.21573231582037	0.423624711511039	0.8629878023971
GO:1990381	ubiquitin-specific protease binding	4/3407	18/18639	0.222222222222222	1.21573231582037	0.423624711511039	0.8629878023971
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/3407	13/18639	0.230769230769231	1.26249125104423	0.433776906533101	0.878231398457787
GO:0003964	RNA-directed DNA polymerase activity	3/3407	13/18639	0.230769230769231	1.26249125104423	0.433776906533101	0.878231398457787
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/3407	13/18639	0.230769230769231	1.26249125104423	0.433776906533101	0.878231398457787
GO:0140666	annealing activity	3/3407	13/18639	0.230769230769231	1.26249125104423	0.433776906533101	0.878231398457787
GO:0003924	GTPase activity	62/3407	331/18639	0.187311178247734	1.02474113629572	0.437482464255157	0.88437315354806
GO:0035250	UDP-galactosyltransferase activity	6/3407	29/18639	0.206896551724138	1.13188870783276	0.441690067398082	0.888953804006713
GO:0043236	laminin binding	6/3407	29/18639	0.206896551724138	1.13188870783276	0.441690067398082	0.888953804006713
GO:0141110	transporter inhibitor activity	9/3407	45/18639	0.2	1.09415908423833	0.441774914757136	0.888953804006713
GO:0005518	collagen binding	14/3407	72/18639	0.194444444444444	1.06376577634282	0.446128453494557	0.896343579845552
GO:0004622	lysophospholipase activity	5/3407	24/18639	0.208333333333333	1.1397490460816	0.45360979933844	0.908600450425246
GO:0030552	cAMP binding	5/3407	24/18639	0.208333333333333	1.1397490460816	0.45360979933844	0.908600450425246
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	25/3407	132/18639	0.189393939393939	1.03613549643782	0.457206447390154	0.914412894780309
GO:0016830	carbon-carbon lyase activity	10/3407	51/18639	0.196078431372549	1.07270498454739	0.459044572089118	0.916695989179483
GO:0009055	electron transfer activity	22/3407	116/18639	0.189655172413793	1.03756464884669	0.461540267057411	0.92028332037508
GO:0003756	protein disulfide isomerase activity	4/3407	19/18639	0.210526315789474	1.1517464044614	0.467754208226971	0.927055027148636
GO:0005520	insulin-like growth factor binding	4/3407	19/18639	0.210526315789474	1.1517464044614	0.467754208226971	0.927055027148636
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/3407	19/18639	0.210526315789474	1.1517464044614	0.467754208226971	0.927055027148636
GO:0120227	acyl-CoA binding	4/3407	19/18639	0.210526315789474	1.1517464044614	0.467754208226971	0.927055027148636
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	23/3407	122/18639	0.188524590163934	1.03137946465089	0.471494884954536	0.933063561804765
GO:0005525	GTP binding	70/3407	378/18639	0.185185185185185	1.01311026318364	0.472825001464264	0.93429084373419
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/3407	57/18639	0.192982456140351	1.05576753742295	0.474383923374573	0.935965881800507
GO:0008187	poly-pyrimidine tract binding	6/3407	30/18639	0.2	1.09415908423833	0.476582185358432	0.936092770047309
GO:0015215	nucleotide transmembrane transporter activity	6/3407	30/18639	0.2	1.09415908423833	0.476582185358432	0.936092770047309
GO:0051721	protein phosphatase 2A binding	6/3407	30/18639	0.2	1.09415908423833	0.476582185358432	0.936092770047309
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	13/3407	68/18639	0.191176470588235	1.0458873599337	0.477905682266827	0.936854286621989
GO:0015399	primary active transmembrane transporter activity	31/3407	166/18639	0.186746987951807	1.02165456660808	0.478994476185162	0.936854286621989
GO:0008137	NADH dehydrogenase (ubiquinone) activity	8/3407	41/18639	0.195121951219512	1.06747227730569	0.481797235408871	0.936854286621989
GO:0042287	MHC protein binding	8/3407	41/18639	0.195121951219512	1.06747227730569	0.481797235408871	0.936854286621989
GO:0140318	protein transporter activity	8/3407	41/18639	0.195121951219512	1.06747227730569	0.481797235408871	0.936854286621989
GO:0005161	platelet-derived growth factor receptor binding	3/3407	14/18639	0.214285714285714	1.17231330454107	0.485512631820818	0.936854286621989
GO:0005313	L-glutamate transmembrane transporter activity	3/3407	14/18639	0.214285714285714	1.17231330454107	0.485512631820818	0.936854286621989
GO:0005347	ATP transmembrane transporter activity	3/3407	14/18639	0.214285714285714	1.17231330454107	0.485512631820818	0.936854286621989
GO:0015386	potassium:proton antiporter activity	3/3407	14/18639	0.214285714285714	1.17231330454107	0.485512631820818	0.936854286621989
GO:0015926	glucosidase activity	3/3407	14/18639	0.214285714285714	1.17231330454107	0.485512631820818	0.936854286621989
GO:0042043	neurexin family protein binding	3/3407	14/18639	0.214285714285714	1.17231330454107	0.485512631820818	0.936854286621989
GO:1990825	sequence-specific mRNA binding	3/3407	14/18639	0.214285714285714	1.17231330454107	0.485512631820818	0.936854286621989
GO:1901682	sulfur compound transmembrane transporter activity	12/3407	63/18639	0.19047619047619	1.04205627070317	0.488195427625128	0.940651804911667
GO:0008194	UDP-glycosyltransferase activity	27/3407	145/18639	0.186206896551724	1.01869983704948	0.49137138864331	0.94090419699441
GO:0004709	MAP kinase kinase kinase activity	5/3407	25/18639	0.2	1.09415908423833	0.491901282319266	0.94090419699441
GO:0015662	P-type ion transporter activity	5/3407	25/18639	0.2	1.09415908423833	0.491901282319266	0.94090419699441
GO:0047617	fatty acyl-CoA hydrolase activity	5/3407	25/18639	0.2	1.09415908423833	0.491901282319266	0.94090419699441
GO:0140358	P-type transmembrane transporter activity	5/3407	25/18639	0.2	1.09415908423833	0.491901282319266	0.94090419699441
GO:0022853	active monoatomic ion transmembrane transporter activity	22/3407	118/18639	0.186440677966102	1.01997880734082	0.496561956066917	0.94844054308282
GO:0043495	protein-membrane adaptor activity	9/3407	47/18639	0.191489361702128	1.04759912320691	0.497584355449078	0.949015959088386
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	11/3407	58/18639	0.189655172413793	1.03756464884669	0.499338777841544	0.950983837394315
GO:0048306	calcium-dependent protein binding	15/3407	80/18639	0.1875	1.02577414147344	0.501983872039608	0.954639849138908
GO:0008238	exopeptidase activity	19/3407	102/18639	0.186274509803922	1.01906973532002	0.503997252604357	0.957085691814334
GO:0016878	acid-thiol ligase activity	6/3407	31/18639	0.193548387096774	1.05886362990806	0.510800423626432	0.967830064270854
GO:0051879	Hsp90 protein binding	8/3407	42/18639	0.19047619047619	1.04205627070317	0.511126059778301	0.967830064270854
GO:0016298	lipase activity	24/3407	130/18639	0.184615384615385	1.00999300083538	0.514324575595909	0.972487272247437
GO:0030971	receptor tyrosine kinase binding	15/3407	81/18639	0.185185185185185	1.01311026318364	0.52300740613524	0.974362801514058
GO:0001786	phosphatidylserine binding	11/3407	59/18639	0.186440677966102	1.01997880734082	0.523981433617488	0.974362801514058
GO:0036002	pre-mRNA binding	11/3407	59/18639	0.186440677966102	1.01997880734082	0.523981433617488	0.974362801514058
GO:0019213	deacetylase activity	7/3407	37/18639	0.189189189189189	1.03501534995518	0.526449183622754	0.974362801514058
GO:0005160	transforming growth factor beta receptor binding	5/3407	26/18639	0.192307692307692	1.05207604253686	0.529154990428391	0.974362801514058
GO:0008157	protein phosphatase 1 binding	5/3407	26/18639	0.192307692307692	1.05207604253686	0.529154990428391	0.974362801514058
GO:0016289	acyl-CoA hydrolase activity	5/3407	26/18639	0.192307692307692	1.05207604253686	0.529154990428391	0.974362801514058
GO:0034237	protein kinase A regulatory subunit binding	5/3407	26/18639	0.192307692307692	1.05207604253686	0.529154990428391	0.974362801514058
GO:0051139	metal cation:proton antiporter activity	5/3407	26/18639	0.192307692307692	1.05207604253686	0.529154990428391	0.974362801514058
GO:0042626	ATPase-coupled transmembrane transporter activity	18/3407	98/18639	0.183673469387755	1.00483997532092	0.532206643024252	0.974362801514058
GO:0004129	cytochrome-c oxidase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0005041	low-density lipoprotein particle receptor activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0010181	FMN binding	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0015929	hexosaminidase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0016846	carbon-sulfur lyase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0031005	filamin binding	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0034483	heparan sulfate sulfotransferase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0047372	monoacylglycerol lipase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0048531	beta-1,3-galactosyltransferase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0050780	dopamine receptor binding	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0051371	muscle alpha-actinin binding	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0140776	protein-containing complex destabilizing activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0141050	histone H3K deacetylase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0141051	histone H4K deacetylase activity	3/3407	15/18639	0.2	1.09415908423833	0.534839578775901	0.974362801514058
GO:0120013	lipid transfer activity	12/3407	65/18639	0.184615384615385	1.00999300083538	0.535307223020261	0.974362801514058
GO:0160215	deacylase activity	12/3407	65/18639	0.184615384615385	1.00999300083538	0.535307223020261	0.974362801514058
GO:0017069	snRNA binding	10/3407	54/18639	0.185185185185185	1.01311026318364	0.537173616330067	0.976409501506034
GO:0008200	ion channel inhibitor activity	8/3407	43/18639	0.186046511627907	1.01782240394264	0.539888084154272	0.978640108466972
GO:0008375	acetylglucosaminyltransferase activity	8/3407	43/18639	0.186046511627907	1.01782240394264	0.539888084154272	0.978640108466972
GO:0070717	poly-purine tract binding	6/3407	32/18639	0.1875	1.02577414147344	0.544142284921792	0.982292519831383
GO:0071813	lipoprotein particle binding	6/3407	32/18639	0.1875	1.02577414147344	0.544142284921792	0.982292519831383
GO:0071814	protein-lipid complex binding	6/3407	32/18639	0.1875	1.02577414147344	0.544142284921792	0.982292519831383
GO:0140299	molecular sensor activity	13/3407	71/18639	0.183098591549296	1.00169493627453	0.545694378028595	0.983744933541961
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/3407	60/18639	0.183333333333333	1.00297916055181	0.548229880524205	0.986963779438925
GO:0010314	phosphatidylinositol-5-phosphate binding	4/3407	21/18639	0.19047619047619	1.04205627070317	0.551755985011577	0.990601468315463
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/3407	21/18639	0.19047619047619	1.04205627070317	0.551755985011577	0.990601468315463
GO:0008235	metalloexopeptidase activity	12/3407	66/18639	0.181818181818182	0.994690076580303	0.558325402762444	0.998958064214005
GO:1902936	phosphatidylinositol bisphosphate binding	20/3407	111/18639	0.18018018018018	0.985728904719219	0.567207723122041	0.998958064214005
GO:0003954	NADH dehydrogenase activity	8/3407	44/18639	0.181818181818182	0.994690076580303	0.567963340528089	0.998958064214005
GO:0005381	iron ion transmembrane transporter activity	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0005528	FK506 binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0008140	cAMP response element binding protein binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0008239	dipeptidyl-peptidase activity	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0015187	glycine transmembrane transporter activity	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0015279	store-operated calcium channel activity	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0016427	tRNA (cytidine) methyltransferase activity	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0031996	thioesterase binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0033204	ribonuclease P RNA binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0035256	G protein-coupled glutamate receptor binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0099122	RNA polymerase II C-terminal domain binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:1990763	arrestin family protein binding	2/3407	10/18639	0.2	1.09415908423833	0.570074092875925	0.998958064214005
GO:0000062	fatty-acyl-CoA binding	3/3407	16/18639	0.1875	1.02577414147344	0.581352523156374	1
GO:0008142	oxysterol binding	3/3407	16/18639	0.1875	1.02577414147344	0.581352523156374	1
GO:0015385	sodium:proton antiporter activity	3/3407	16/18639	0.1875	1.02577414147344	0.581352523156374	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/3407	16/18639	0.1875	1.02577414147344	0.581352523156374	1
GO:0030275	LRR domain binding	3/3407	16/18639	0.1875	1.02577414147344	0.581352523156374	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/3407	16/18639	0.1875	1.02577414147344	0.581352523156374	1
GO:0055102	lipase inhibitor activity	3/3407	16/18639	0.1875	1.02577414147344	0.581352523156374	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/3407	39/18639	0.179487179487179	0.981937639701068	0.586345826440941	1
GO:0008649	rRNA methyltransferase activity	4/3407	22/18639	0.181818181818182	0.994690076580303	0.591013508485411	1
GO:0033691	sialic acid binding	4/3407	22/18639	0.181818181818182	0.994690076580303	0.591013508485411	1
GO:0008009	chemokine activity	8/3407	45/18639	0.177777777777778	0.972585852656296	0.595247324478565	1
GO:0005126	cytokine receptor binding	49/3407	275/18639	0.178181818181818	0.974796275048697	0.603595697783019	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	23/3407	130/18639	0.176923076923077	0.96790995913391	0.604600454985758	1
GO:0016831	carboxy-lyase activity	6/3407	34/18639	0.176470588235294	0.965434486092647	0.607538875799514	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/3407	40/18639	0.175	0.957389198708541	0.614835644097326	1
GO:0050997	quaternary ammonium group binding	7/3407	40/18639	0.175	0.957389198708541	0.614835644097326	1
GO:0061791	GTPase motor activity	7/3407	40/18639	0.175	0.957389198708541	0.614835644097326	1
GO:0071949	FAD binding	7/3407	40/18639	0.175	0.957389198708541	0.614835644097326	1
GO:1990606	membrane scission GTPase motor activity	7/3407	40/18639	0.175	0.957389198708541	0.614835644097326	1
GO:0001851	complement component C3b binding	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0003953	NAD+ nucleosidase activity	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0004016	adenylate cyclase activity	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0005114	type II transforming growth factor beta receptor binding	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0005536	D-glucose binding	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0008199	ferric iron binding	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0015173	aromatic amino acid transmembrane transporter activity	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0034056	estrogen response element binding	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0034511	U3 snoRNA binding	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0047676	arachidonate-CoA ligase activity	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0050998	nitric-oxide synthase binding	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0140537	transcription regulator activator activity	2/3407	11/18639	0.181818181818182	0.994690076580303	0.624403579390933	1
GO:0004549	tRNA-specific ribonuclease activity	3/3407	17/18639	0.176470588235294	0.965434486092647	0.624793767118997	1
GO:0008484	sulfuric ester hydrolase activity	3/3407	17/18639	0.176470588235294	0.965434486092647	0.624793767118997	1
GO:0016018	cyclosporin A binding	3/3407	17/18639	0.176470588235294	0.965434486092647	0.624793767118997	1
GO:0045125	bioactive lipid receptor activity	3/3407	17/18639	0.176470588235294	0.965434486092647	0.624793767118997	1
GO:1901567	fatty acid derivative binding	3/3407	17/18639	0.176470588235294	0.965434486092647	0.624793767118997	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3407	23/18639	0.173913043478261	0.951442681946376	0.62816067495997	1
GO:0140102	catalytic activity, acting on a rRNA	4/3407	23/18639	0.173913043478261	0.951442681946376	0.62816067495997	1
GO:0019001	guanyl nucleotide binding	71/3407	400/18639	0.1775	0.97106618726152	0.629388226336371	1
GO:0032561	guanyl ribonucleotide binding	71/3407	400/18639	0.1775	0.97106618726152	0.629388226336371	1
GO:0051861	glycolipid binding	5/3407	29/18639	0.172413793103448	0.943240589860632	0.632560824376951	1
GO:0016782	transferase activity, transferring sulphur-containing groups	12/3407	70/18639	0.171428571428571	0.937850643632857	0.645400329729416	1
GO:0005178	integrin binding	28/3407	161/18639	0.173913043478261	0.951442681946376	0.646800350482817	1
GO:0051213	dioxygenase activity	16/3407	93/18639	0.172043010752688	0.941212115473835	0.64763086018219	1
GO:0017022	myosin binding	13/3407	76/18639	0.171052631578947	0.93579395362489	0.650669027253883	1
GO:0038024	cargo receptor activity	11/3407	65/18639	0.169230769230769	0.925826917432436	0.661202296792728	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/3407	24/18639	0.166666666666667	0.911799236865277	0.663070850084277	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/3407	24/18639	0.166666666666667	0.911799236865277	0.663070850084277	1
GO:0005315	phosphate transmembrane transporter activity	4/3407	24/18639	0.166666666666667	0.911799236865277	0.663070850084277	1
GO:0030215	semaphorin receptor binding	4/3407	24/18639	0.166666666666667	0.911799236865277	0.663070850084277	1
GO:0050699	WW domain binding	4/3407	24/18639	0.166666666666667	0.911799236865277	0.663070850084277	1
GO:0070840	dynein complex binding	4/3407	24/18639	0.166666666666667	0.911799236865277	0.663070850084277	1
GO:0001965	G-protein alpha-subunit binding	5/3407	30/18639	0.166666666666667	0.911799236865277	0.663756552180655	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	5/3407	30/18639	0.166666666666667	0.911799236865277	0.663756552180655	1
GO:0016769	transferase activity, transferring nitrogenous groups	5/3407	30/18639	0.166666666666667	0.911799236865277	0.663756552180655	1
GO:0008308	voltage-gated monoatomic anion channel activity	3/3407	18/18639	0.166666666666667	0.911799236865277	0.665027578240589	1
GO:0017128	phospholipid scramblase activity	3/3407	18/18639	0.166666666666667	0.911799236865277	0.665027578240589	1
GO:0004190	aspartic-type endopeptidase activity	6/3407	36/18639	0.166666666666667	0.911799236865277	0.665749419583568	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	6/3407	36/18639	0.166666666666667	0.911799236865277	0.665749419583568	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	6/3407	36/18639	0.166666666666667	0.911799236865277	0.665749419583568	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	6/3407	36/18639	0.166666666666667	0.911799236865277	0.665749419583568	1
GO:0016859	cis-trans isomerase activity	7/3407	42/18639	0.166666666666667	0.911799236865277	0.668445873695927	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	8/3407	48/18639	0.166666666666667	0.911799236865277	0.671536899341795	1
GO:0004175	endopeptidase activity	71/3407	405/18639	0.175308641975309	0.959077715813847	0.673018015703872	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0003720	telomerase activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0005165	neurotrophin receptor binding	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0005527	macrolide binding	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0008179	adenylate cyclase binding	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0010853	cyclase activator activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0015132	prostaglandin transmembrane transporter activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0016801	hydrolase activity, acting on ether bonds	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0016803	ether hydrolase activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0016840	carbon-nitrogen lyase activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0035251	UDP-glucosyltransferase activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0070008	serine-type exopeptidase activity	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0070410	co-SMAD binding	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0097371	MDM2/MDM4 family protein binding	2/3407	12/18639	0.166666666666667	0.911799236865277	0.673242077916796	1
GO:0001540	amyloid-beta binding	14/3407	83/18639	0.168674698795181	0.922784769839558	0.674288221458842	1
GO:0030165	PDZ domain binding	14/3407	83/18639	0.168674698795181	0.922784769839558	0.674288221458842	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/3407	54/18639	0.166666666666667	0.911799236865277	0.674850457757787	1
GO:0023023	MHC protein complex binding	6/3407	37/18639	0.162162162162162	0.887156014247297	0.692710755575984	1
GO:0070001	aspartic-type peptidase activity	6/3407	37/18639	0.162162162162162	0.887156014247297	0.692710755575984	1
GO:0016411	acylglycerol O-acyltransferase activity	5/3407	31/18639	0.161290322580645	0.88238635825672	0.693171192287237	1
GO:0047499	calcium-independent phospholipase A2 activity	5/3407	31/18639	0.161290322580645	0.88238635825672	0.693171192287237	1
GO:0003707	nuclear steroid receptor activity	4/3407	25/18639	0.16	0.875327267390666	0.695674577277612	1
GO:0008483	transaminase activity	4/3407	25/18639	0.16	0.875327267390666	0.695674577277612	1
GO:0008374	O-acyltransferase activity	9/3407	55/18639	0.163636363636364	0.895221068922272	0.696862229425992	1
GO:0098632	cell-cell adhesion mediator activity	9/3407	55/18639	0.163636363636364	0.895221068922272	0.696862229425992	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/3407	19/18639	0.157894736842105	0.863809803346052	0.702016335118142	1
GO:0022821	solute:potassium antiporter activity	3/3407	19/18639	0.157894736842105	0.863809803346052	0.702016335118142	1
GO:0034987	immunoglobulin receptor binding	3/3407	19/18639	0.157894736842105	0.863809803346052	0.702016335118142	1
GO:0046527	glucosyltransferase activity	3/3407	19/18639	0.157894736842105	0.863809803346052	0.702016335118142	1
GO:0046624	sphingolipid transporter activity	3/3407	19/18639	0.157894736842105	0.863809803346052	0.702016335118142	1
GO:0070003	threonine-type peptidase activity	3/3407	19/18639	0.157894736842105	0.863809803346052	0.702016335118142	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	15/3407	91/18639	0.164835164835165	0.901779465031593	0.712447229161959	1
GO:0072341	modified amino acid binding	15/3407	91/18639	0.164835164835165	0.901779465031593	0.712447229161959	1
GO:0002161	aminoacyl-tRNA editing activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0005542	folic acid binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0008035	high-density lipoprotein particle binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0008417	fucosyltransferase activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0009982	pseudouridine synthase activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0019855	calcium channel inhibitor activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0031432	titin binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0031994	insulin-like growth factor I binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0035325	Toll-like receptor binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0051011	microtubule minus-end binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0061459	L-arginine transmembrane transporter activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0071714	icosanoid transmembrane transporter activity	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0071837	HMG box domain binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0097157	pre-mRNA intronic binding	2/3407	13/18639	0.153846153846154	0.841660834029487	0.716781199986559	1
GO:0019212	phosphatase inhibitor activity	9/3407	56/18639	0.160714285714286	0.879234978405803	0.717910868899016	1
GO:0005319	lipid transporter activity	30/3407	178/18639	0.168539325842697	0.922044172110955	0.718447454584547	1
GO:0015179	L-amino acid transmembrane transporter activity	10/3407	62/18639	0.161290322580645	0.88238635825672	0.719098519365674	1
GO:0031369	translation initiation factor binding	5/3407	32/18639	0.15625	0.854811784561198	0.720769138095652	1
GO:0042910	xenobiotic transmembrane transporter activity	5/3407	32/18639	0.15625	0.854811784561198	0.720769138095652	1
GO:0043425	bHLH transcription factor binding	5/3407	32/18639	0.15625	0.854811784561198	0.720769138095652	1
GO:0047498	calcium-dependent phospholipase A2 activity	5/3407	32/18639	0.15625	0.854811784561198	0.720769138095652	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/3407	26/18639	0.153846153846154	0.841660834029487	0.725950865795652	1
GO:0005227	calcium-activated cation channel activity	4/3407	26/18639	0.153846153846154	0.841660834029487	0.725950865795652	1
GO:0008143	poly(A) binding	4/3407	26/18639	0.153846153846154	0.841660834029487	0.725950865795652	1
GO:0015216	purine nucleotide transmembrane transporter activity	4/3407	26/18639	0.153846153846154	0.841660834029487	0.725950865795652	1
GO:0030507	spectrin binding	4/3407	26/18639	0.153846153846154	0.841660834029487	0.725950865795652	1
GO:0050660	flavin adenine dinucleotide binding	14/3407	86/18639	0.162790697674419	0.890594603449806	0.726429993700315	1
GO:0016408	C-acyltransferase activity	3/3407	20/18639	0.15	0.82061931317875	0.735799103704507	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/3407	20/18639	0.15	0.82061931317875	0.735799103704507	1
GO:0001618	virus receptor activity	13/3407	81/18639	0.160493827160494	0.878028894759156	0.741122686292412	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/3407	39/18639	0.153846153846154	0.841660834029487	0.742156061198004	1
GO:0004364	glutathione transferase activity	4/3407	27/18639	0.148148148148148	0.810488210546913	0.753918838291136	1
GO:0016405	CoA-ligase activity	4/3407	27/18639	0.148148148148148	0.810488210546913	0.753918838291136	1
GO:0004065	arylsulfatase activity	2/3407	14/18639	0.142857142857143	0.781542203027381	0.755325961347516	1
GO:0008494	translation activator activity	2/3407	14/18639	0.142857142857143	0.781542203027381	0.755325961347516	1
GO:0032036	myosin heavy chain binding	2/3407	14/18639	0.142857142857143	0.781542203027381	0.755325961347516	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/3407	14/18639	0.142857142857143	0.781542203027381	0.755325961347516	1
GO:1901474	azole transmembrane transporter activity	2/3407	14/18639	0.142857142857143	0.781542203027381	0.755325961347516	1
GO:1901612	cardiolipin binding	2/3407	14/18639	0.142857142857143	0.781542203027381	0.755325961347516	1
GO:0098631	cell adhesion mediator activity	12/3407	76/18639	0.157894736842105	0.863809803346052	0.756588390671458	1
GO:0140272	exogenous protein binding	13/3407	82/18639	0.158536585365854	0.867321225310874	0.757211710247423	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	14/3407	88/18639	0.159090909090909	0.870353817007765	0.75808482980306	1
GO:0004180	carboxypeptidase activity	7/3407	46/18639	0.152173913043478	0.832512346703079	0.760822736682223	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/3407	46/18639	0.152173913043478	0.832512346703079	0.760822736682223	1
GO:0005200	structural constituent of cytoskeleton	18/3407	112/18639	0.160714285714286	0.879234978405803	0.763181880533986	1
GO:0005123	death receptor binding	3/3407	21/18639	0.142857142857143	0.781542203027381	0.766472956819996	1
GO:0009975	cyclase activity	3/3407	21/18639	0.142857142857143	0.781542203027381	0.766472956819996	1
GO:0015174	basic amino acid transmembrane transporter activity	3/3407	21/18639	0.142857142857143	0.781542203027381	0.766472956819996	1
GO:0035613	RNA stem-loop binding	3/3407	21/18639	0.142857142857143	0.781542203027381	0.766472956819996	1
GO:1904047	S-adenosyl-L-methionine binding	3/3407	21/18639	0.142857142857143	0.781542203027381	0.766472956819996	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	21/3407	130/18639	0.161538461538462	0.883743875730961	0.767948397389806	1
GO:0005544	calcium-dependent phospholipid binding	8/3407	53/18639	0.150943396226415	0.825780440934591	0.777375621568848	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	8/3407	53/18639	0.150943396226415	0.825780440934591	0.777375621568848	1
GO:0050698	proteoglycan sulfotransferase activity	4/3407	28/18639	0.142857142857143	0.781542203027381	0.779629965810708	1
GO:0051019	mitogen-activated protein kinase binding	4/3407	28/18639	0.142857142857143	0.781542203027381	0.779629965810708	1
GO:0051393	alpha-actinin binding	4/3407	28/18639	0.142857142857143	0.781542203027381	0.779629965810708	1
GO:0051959	dynein light intermediate chain binding	4/3407	28/18639	0.142857142857143	0.781542203027381	0.779629965810708	1
GO:0005516	calmodulin binding	34/3407	207/18639	0.164251207729469	0.898584755171578	0.781456344866014	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/3407	15/18639	0.133333333333333	0.729439389492222	0.78924694328161	1
GO:0008242	omega peptidase activity	2/3407	15/18639	0.133333333333333	0.729439389492222	0.78924694328161	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/3407	15/18639	0.133333333333333	0.729439389492222	0.78924694328161	1
GO:0031386	protein tag activity	2/3407	15/18639	0.133333333333333	0.729439389492222	0.78924694328161	1
GO:0033130	acetylcholine receptor binding	2/3407	15/18639	0.133333333333333	0.729439389492222	0.78924694328161	1
GO:0042809	nuclear vitamin D receptor binding	2/3407	15/18639	0.133333333333333	0.729439389492222	0.78924694328161	1
GO:0141047	molecular tag activity	2/3407	15/18639	0.133333333333333	0.729439389492222	0.78924694328161	1
GO:0004623	phospholipase A2 activity	5/3407	35/18639	0.142857142857143	0.781542203027381	0.792704264262142	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/3407	22/18639	0.136363636363636	0.746017557435227	0.794177080241246	1
GO:0140784	metal ion sensor activity	3/3407	22/18639	0.136363636363636	0.746017557435227	0.794177080241246	1
GO:0042277	peptide binding	41/3407	249/18639	0.164658634538153	0.900813703890997	0.794585369647985	1
GO:0033293	monocarboxylic acid binding	12/3407	79/18639	0.151898734177215	0.831006899421519	0.802286885327656	1
GO:0003785	actin monomer binding	4/3407	29/18639	0.137931034482759	0.754592471888505	0.80316102844011	1
GO:0099604	ligand-gated calcium channel activity	4/3407	29/18639	0.137931034482759	0.754592471888505	0.80316102844011	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	10/3407	67/18639	0.149253731343284	0.816536630028607	0.80564982424484	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	44/3407	268/18639	0.164179104477612	0.898190293031467	0.807799538204875	1
GO:0004033	aldo-keto reductase (NADPH) activity	5/3407	36/18639	0.138888888888889	0.759832697387731	0.813180852113525	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/3407	36/18639	0.138888888888889	0.759832697387731	0.813180852113525	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	13/3407	86/18639	0.151162790697674	0.826980703203391	0.814685384480575	1
GO:0000049	tRNA binding	12/3407	80/18639	0.15	0.82061931317875	0.816040511534468	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0005149	interleukin-1 receptor binding	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0017070	U6 snRNA binding	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0019841	retinol binding	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/3407	16/18639	0.125	0.683849427648958	0.818946146156644	1
GO:0000295	adenine nucleotide transmembrane transporter activity	3/3407	23/18639	0.130434782608696	0.713582011459782	0.819079541033437	1
GO:0004602	glutathione peroxidase activity	3/3407	23/18639	0.130434782608696	0.713582011459782	0.819079541033437	1
GO:0016849	phosphorus-oxygen lyase activity	3/3407	23/18639	0.130434782608696	0.713582011459782	0.819079541033437	1
GO:0017134	fibroblast growth factor binding	3/3407	23/18639	0.130434782608696	0.713582011459782	0.819079541033437	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/3407	30/18639	0.133333333333333	0.729439389492222	0.824607870941564	1
GO:0022839	monoatomic ion-gated channel activity	4/3407	30/18639	0.133333333333333	0.729439389492222	0.824607870941564	1
GO:0022829	wide pore channel activity	5/3407	37/18639	0.135135135135135	0.739296678539414	0.832004304697515	1
GO:0030551	cyclic nucleotide binding	5/3407	37/18639	0.135135135135135	0.739296678539414	0.832004304697515	1
GO:0042805	actinin binding	5/3407	37/18639	0.135135135135135	0.739296678539414	0.832004304697515	1
GO:0048020	CCR chemokine receptor binding	7/3407	50/18639	0.14	0.765911358966833	0.832983762676772	1
GO:0004806	triacylglycerol lipase activity	3/3407	24/18639	0.125	0.683849427648958	0.841366496883317	1
GO:0019957	C-C chemokine binding	3/3407	24/18639	0.125	0.683849427648958	0.841366496883317	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/3407	24/18639	0.125	0.683849427648958	0.841366496883317	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/3407	24/18639	0.125	0.683849427648958	0.841366496883317	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/3407	24/18639	0.125	0.683849427648958	0.841366496883317	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/3407	31/18639	0.129032258064516	0.705909086605376	0.844079971482946	1
GO:0070325	lipoprotein particle receptor binding	4/3407	31/18639	0.129032258064516	0.705909086605376	0.844079971482946	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/3407	17/18639	0.117647058823529	0.643622990728431	0.84483313002833	1
GO:0016805	dipeptidase activity	2/3407	17/18639	0.117647058823529	0.643622990728431	0.84483313002833	1
GO:0032977	membrane insertase activity	2/3407	17/18639	0.117647058823529	0.643622990728431	0.84483313002833	1
GO:0045236	CXCR chemokine receptor binding	2/3407	17/18639	0.117647058823529	0.643622990728431	0.84483313002833	1
GO:0048038	quinone binding	2/3407	17/18639	0.117647058823529	0.643622990728431	0.84483313002833	1
GO:0015078	proton transmembrane transporter activity	29/3407	185/18639	0.156756756756757	0.85758414710572	0.84555812013865	1
GO:0016597	amino acid binding	7/3407	51/18639	0.137254901960784	0.75089348918317	0.848034508463999	1
GO:0000146	microfilament motor activity	5/3407	38/18639	0.131578947368421	0.719841502788377	0.849249615128841	1
GO:0042605	peptide antigen binding	6/3407	45/18639	0.133333333333333	0.729439389492222	0.855430793889295	1
GO:0046982	protein heterodimerization activity	60/3407	369/18639	0.16260162601626	0.889560231088075	0.8608678390633	1
GO:0015645	fatty acid ligase activity	3/3407	25/18639	0.12	0.656495450543	0.86123357682955	1
GO:0120515	fatty acid-CoA ligase activity	3/3407	25/18639	0.12	0.656495450543	0.86123357682955	1
GO:0015106	bicarbonate transmembrane transporter activity	4/3407	32/18639	0.125	0.683849427648958	0.861695804823988	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/3407	32/18639	0.125	0.683849427648958	0.861695804823988	1
GO:0051082	unfolded protein binding	18/3407	121/18639	0.148760330578512	0.813837335383884	0.863399506713279	1
GO:0004857	enzyme inhibitor activity	68/3407	416/18639	0.163461538461538	0.89426463615633	0.864046494801376	1
GO:0000182	rDNA binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0001094	TFIID-class transcription factor complex binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0003796	lysozyme activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0008190	eukaryotic initiation factor 4E binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0015203	polyamine transmembrane transporter activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0015643	toxic substance binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0019911	structural constituent of myelin sheath	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0031434	mitogen-activated protein kinase kinase binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0032052	bile acid binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0043121	neurotrophin binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0043208	glycosphingolipid binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0043295	glutathione binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0050308	sugar-phosphatase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0050815	phosphoserine residue binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0051378	serotonin binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0070739	protein-glutamic acid ligase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0070740	tubulin-glutamic acid ligase activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0097177	mitochondrial ribosome binding	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0141109	transporter activator activity	1/3407	10/18639	0.1	0.547079542119166	0.867227353089692	1
GO:0003746	translation elongation factor activity	2/3407	18/18639	0.111111111111111	0.607866157910185	0.867308824001798	1
GO:0032393	MHC class I receptor activity	2/3407	18/18639	0.111111111111111	0.607866157910185	0.867308824001798	1
GO:0070064	proline-rich region binding	2/3407	18/18639	0.111111111111111	0.607866157910185	0.867308824001798	1
GO:0099602	neurotransmitter receptor regulator activity	2/3407	18/18639	0.111111111111111	0.607866157910185	0.867308824001798	1
GO:1901611	phosphatidylglycerol binding	2/3407	18/18639	0.111111111111111	0.607866157910185	0.867308824001798	1
GO:0042379	chemokine receptor binding	10/3407	72/18639	0.138888888888889	0.759832697387731	0.870627331470047	1
GO:0001217	DNA-binding transcription repressor activity	44/3407	278/18639	0.158273381294964	0.865881289685012	0.874823376903686	1
GO:0004864	protein phosphatase inhibitor activity	7/3407	53/18639	0.132075471698113	0.722557885817767	0.874845324617051	1
GO:0005246	calcium channel regulator activity	7/3407	53/18639	0.132075471698113	0.722557885817767	0.874845324617051	1
GO:0005112	Notch binding	3/3407	26/18639	0.115384615384615	0.631245625522115	0.878879147833972	1
GO:0030247	polysaccharide binding	3/3407	26/18639	0.115384615384615	0.631245625522115	0.878879147833972	1
GO:0120014	phospholipid transfer activity	3/3407	26/18639	0.115384615384615	0.631245625522115	0.878879147833972	1
GO:0052689	carboxylic ester hydrolase activity	13/3407	92/18639	0.141304347826087	0.773047179081431	0.881075166083372	1
GO:0005504	fatty acid binding	6/3407	47/18639	0.127659574468085	0.698399415471276	0.882631449607057	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/3407	19/18639	0.105263157894737	0.575873202230701	0.886754999164581	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/3407	19/18639	0.105263157894737	0.575873202230701	0.886754999164581	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/3407	19/18639	0.105263157894737	0.575873202230701	0.886754999164581	1
GO:0016918	retinal binding	2/3407	19/18639	0.105263157894737	0.575873202230701	0.886754999164581	1
GO:0043395	heparan sulfate proteoglycan binding	2/3407	19/18639	0.105263157894737	0.575873202230701	0.886754999164581	1
GO:0141147	intracellularly calcium-gated channel activity	2/3407	19/18639	0.105263157894737	0.575873202230701	0.886754999164581	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0008046	axon guidance receptor activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0008503	benzodiazepine receptor activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0008526	phosphatidylinositol transfer activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0010854	adenylate cyclase regulator activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0019203	carbohydrate phosphatase activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0019864	IgG binding	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0043522	leucine zipper domain binding	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0048185	activin binding	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0070697	activin receptor binding	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:1900750	oligopeptide binding	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:1990948	ubiquitin ligase inhibitor activity	1/3407	11/18639	0.0909090909090909	0.497345038290151	0.891509730459568	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3407	41/18639	0.121951219512195	0.667170173316057	0.892356031406467	1
GO:0035255	ionotropic glutamate receptor binding	3/3407	27/18639	0.111111111111111	0.607866157910185	0.894499186526826	1
GO:0038187	pattern recognition receptor activity	6/3407	48/18639	0.125	0.683849427648958	0.894526537661213	1
GO:0001614	purinergic nucleotide receptor activity	2/3407	20/18639	0.1	0.547079542119166	0.903527876437923	1
GO:0001972	retinoic acid binding	2/3407	20/18639	0.1	0.547079542119166	0.903527876437923	1
GO:0010851	cyclase regulator activity	2/3407	20/18639	0.1	0.547079542119166	0.903527876437923	1
GO:0015464	acetylcholine receptor activity	2/3407	20/18639	0.1	0.547079542119166	0.903527876437923	1
GO:0016502	nucleotide receptor activity	2/3407	20/18639	0.1	0.547079542119166	0.903527876437923	1
GO:0016229	steroid dehydrogenase activity	4/3407	35/18639	0.114285714285714	0.625233762421904	0.904648560585129	1
GO:0141108	transporter regulator activity	25/3407	170/18639	0.147058823529412	0.804528738410539	0.907903882128699	1
GO:0016866	intramolecular transferase activity	3/3407	28/18639	0.107142857142857	0.586156652270535	0.90828349301276	1
GO:0004000	adenosine deaminase activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0004032	aldose reductase (NADPH) activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0004859	phospholipase inhibitor activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0005436	sodium:phosphate symporter activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0015166	polyol transmembrane transporter activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0015269	calcium-activated potassium channel activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0015368	calcium:monoatomic cation antiporter activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0016208	AMP binding	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0016361	activin receptor activity, type I	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0016362	activin receptor activity, type II	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0017002	activin receptor activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0031543	peptidyl-proline dioxygenase activity	1/3407	12/18639	0.0833333333333333	0.455899618432639	0.911352244327093	1
GO:0045505	dynein intermediate chain binding	4/3407	36/18639	0.111111111111111	0.607866157910185	0.91608202414408	1
GO:0001846	opsonin binding	2/3407	21/18639	0.0952380952380952	0.521028135351587	0.917954710081915	1
GO:0061891	calcium ion sensor activity	2/3407	21/18639	0.0952380952380952	0.521028135351587	0.917954710081915	1
GO:0015297	antiporter activity	19/3407	135/18639	0.140740740740741	0.769963800019568	0.920074418549532	1
GO:0099106	ion channel regulator activity	23/3407	160/18639	0.14375	0.786426841796302	0.920580471643788	1
GO:0043394	proteoglycan binding	4/3407	37/18639	0.108108108108108	0.591437342831531	0.926273262864875	1
GO:0004993	G protein-coupled serotonin receptor activity	1/3407	13/18639	0.0769230769230769	0.420830417014743	0.927566498022138	1
GO:0017154	semaphorin receptor activity	1/3407	13/18639	0.0769230769230769	0.420830417014743	0.927566498022138	1
GO:0032396	inhibitory MHC class I receptor activity	1/3407	13/18639	0.0769230769230769	0.420830417014743	0.927566498022138	1
GO:0045159	myosin II binding	1/3407	13/18639	0.0769230769230769	0.420830417014743	0.927566498022138	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/3407	13/18639	0.0769230769230769	0.420830417014743	0.927566498022138	1
GO:0070700	BMP receptor binding	1/3407	13/18639	0.0769230769230769	0.420830417014743	0.927566498022138	1
GO:0089720	caspase binding	1/3407	13/18639	0.0769230769230769	0.420830417014743	0.927566498022138	1
GO:0016247	channel regulator activity	24/3407	168/18639	0.142857142857143	0.781542203027381	0.929496197748205	1
GO:0015377	chloride:monoatomic cation symporter activity	2/3407	22/18639	0.0909090909090909	0.497345038290151	0.930332473065982	1
GO:0098918	structural constituent of synapse	3/3407	30/18639	0.1	0.547079542119166	0.93105802340178	1
GO:0005080	protein kinase C binding	6/3407	52/18639	0.115384615384615	0.631245625522115	0.932326888715458	1
GO:0005109	frizzled binding	4/3407	38/18639	0.105263157894737	0.575873202230701	0.935334868480879	1
GO:0005501	retinoid binding	4/3407	38/18639	0.105263157894737	0.575873202230701	0.935334868480879	1
GO:0019840	isoprenoid binding	4/3407	38/18639	0.105263157894737	0.575873202230701	0.935334868480879	1
GO:0008146	sulfotransferase activity	6/3407	53/18639	0.113207547169811	0.619335330700943	0.939664960728021	1
GO:0005452	solute:inorganic anion antiporter activity	3/3407	31/18639	0.0967741935483871	0.529431814954032	0.940377100393084	1
GO:0008327	methyl-CpG binding	3/3407	31/18639	0.0967741935483871	0.529431814954032	0.940377100393084	1
GO:0005344	oxygen carrier activity	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0008191	metalloendopeptidase inhibitor activity	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0019763	immunoglobulin receptor activity	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0031404	chloride ion binding	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0042813	Wnt receptor activity	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0043176	amine binding	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0061783	peptidoglycan muralytic activity	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0098821	BMP receptor activity	1/3407	14/18639	0.0714285714285714	0.39077110151369	0.940815770074031	1
GO:0005212	structural constituent of eye lens	2/3407	23/18639	0.0869565217391304	0.475721340973188	0.940927990402415	1
GO:0005283	amino acid:sodium symporter activity	2/3407	23/18639	0.0869565217391304	0.475721340973188	0.940927990402415	1
GO:0016493	C-C chemokine receptor activity	2/3407	23/18639	0.0869565217391304	0.475721340973188	0.940927990402415	1
GO:0099186	structural constituent of postsynapse	2/3407	23/18639	0.0869565217391304	0.475721340973188	0.940927990402415	1
GO:0008237	metallopeptidase activity	26/3407	184/18639	0.141304347826087	0.773047179081431	0.944331405693806	1
GO:0061135	endopeptidase regulator activity	26/3407	184/18639	0.141304347826087	0.773047179081431	0.944331405693806	1
GO:0015026	coreceptor activity	7/3407	61/18639	0.114754098360656	0.627796195874453	0.945937267126453	1
GO:0015149	hexose transmembrane transporter activity	2/3407	24/18639	0.0833333333333333	0.455899618432639	0.949979035267787	1
GO:0015295	solute:proton symporter activity	2/3407	24/18639	0.0833333333333333	0.455899618432639	0.949979035267787	1
GO:0048027	mRNA 5'-UTR binding	2/3407	24/18639	0.0833333333333333	0.455899618432639	0.949979035267787	1
GO:0050431	transforming growth factor beta binding	2/3407	24/18639	0.0833333333333333	0.455899618432639	0.949979035267787	1
GO:0055056	D-glucose transmembrane transporter activity	2/3407	24/18639	0.0833333333333333	0.455899618432639	0.949979035267787	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/3407	24/18639	0.0833333333333333	0.455899618432639	0.949979035267787	1
GO:0004896	cytokine receptor activity	12/3407	96/18639	0.125	0.683849427648958	0.95106503248994	1
GO:0004089	carbonate dehydratase activity	1/3407	15/18639	0.0666666666666667	0.364719694746111	0.951642114844919	1
GO:0005523	tropomyosin binding	1/3407	15/18639	0.0666666666666667	0.364719694746111	0.951642114844919	1
GO:0045504	dynein heavy chain binding	1/3407	15/18639	0.0666666666666667	0.364719694746111	0.951642114844919	1
GO:0008135	translation factor activity, RNA binding	10/3407	83/18639	0.120481927710843	0.659131978456827	0.953064634776029	1
GO:0004222	metalloendopeptidase activity	14/3407	110/18639	0.127272727272727	0.696283053606212	0.95429043547676	1
GO:0031406	carboxylic acid binding	26/3407	187/18639	0.13903743315508	0.760645352679055	0.954551603728889	1
GO:0042923	neuropeptide binding	3/3407	33/18639	0.0909090909090909	0.497345038290151	0.955610303612637	1
GO:0001530	lipopolysaccharide binding	4/3407	41/18639	0.0975609756097561	0.533736138652845	0.956772914196915	1
GO:0004812	aminoacyl-tRNA ligase activity	4/3407	41/18639	0.0975609756097561	0.533736138652845	0.956772914196915	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	4/3407	41/18639	0.0975609756097561	0.533736138652845	0.956772914196915	1
GO:0005507	copper ion binding	7/3407	63/18639	0.111111111111111	0.607866157910185	0.956785260550151	1
GO:0180051	translation factor activity	10/3407	84/18639	0.119047619047619	0.651285169189484	0.957505792528926	1
GO:0030170	pyridoxal phosphate binding	6/3407	56/18639	0.107142857142857	0.586156652270535	0.957601511221814	1
GO:0001848	complement binding	2/3407	25/18639	0.08	0.437663633695333	0.957696031653721	1
GO:0005537	D-mannose binding	2/3407	25/18639	0.08	0.437663633695333	0.957696031653721	1
GO:0015271	outward rectifier potassium channel activity	2/3407	25/18639	0.08	0.437663633695333	0.957696031653721	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/3407	25/18639	0.08	0.437663633695333	0.957696031653721	1
GO:0019842	vitamin binding	20/3407	150/18639	0.133333333333333	0.729439389492222	0.957973329410826	1
GO:0061134	peptidase regulator activity	32/3407	226/18639	0.141592920353982	0.774625900345722	0.958866631279017	1
GO:0043177	organic acid binding	26/3407	189/18639	0.137566137566138	0.752596195507848	0.960432621690164	1
GO:0005024	transforming growth factor beta receptor activity	1/3407	16/18639	0.0625	0.341924713824479	0.96048851275747	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/3407	16/18639	0.0625	0.341924713824479	0.96048851275747	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/3407	16/18639	0.0625	0.341924713824479	0.96048851275747	1
GO:0015020	glucuronosyltransferase activity	3/3407	34/18639	0.0882352941176471	0.482717243046323	0.96178017879583	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/3407	34/18639	0.0882352941176471	0.482717243046323	0.96178017879583	1
GO:0051427	hormone receptor binding	3/3407	34/18639	0.0882352941176471	0.482717243046323	0.96178017879583	1
GO:0090482	vitamin transmembrane transporter activity	3/3407	34/18639	0.0882352941176471	0.482717243046323	0.96178017879583	1
GO:0008307	structural constituent of muscle	4/3407	42/18639	0.0952380952380952	0.521028135351587	0.962312924350813	1
GO:0070279	vitamin B6 binding	6/3407	57/18639	0.105263157894737	0.575873202230701	0.962406682428174	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/3407	26/18639	0.0769230769230769	0.420830417014743	0.964264105305367	1
GO:0004950	chemokine receptor activity	2/3407	26/18639	0.0769230769230769	0.420830417014743	0.964264105305367	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/3407	26/18639	0.0769230769230769	0.420830417014743	0.964264105305367	1
GO:0015145	monosaccharide transmembrane transporter activity	2/3407	26/18639	0.0769230769230769	0.420830417014743	0.964264105305367	1
GO:0050750	low-density lipoprotein particle receptor binding	2/3407	26/18639	0.0769230769230769	0.420830417014743	0.964264105305367	1
GO:0005245	voltage-gated calcium channel activity	4/3407	43/18639	0.0930232558139535	0.508911201971318	0.967187361501125	1
GO:0008569	minus-end-directed microtubule motor activity	1/3407	17/18639	0.0588235294117647	0.321811495364216	0.967716974178042	1
GO:0030548	acetylcholine receptor regulator activity	1/3407	17/18639	0.0588235294117647	0.321811495364216	0.967716974178042	1
GO:0036041	long-chain fatty acid binding	1/3407	17/18639	0.0588235294117647	0.321811495364216	0.967716974178042	1
GO:0070492	oligosaccharide binding	1/3407	17/18639	0.0588235294117647	0.321811495364216	0.967716974178042	1
GO:0003743	translation initiation factor activity	5/3407	51/18639	0.0980392156862745	0.536352492273693	0.968563825084238	1
GO:0042562	hormone binding	11/3407	94/18639	0.117021276595745	0.640199464182003	0.968990620504143	1
GO:0022804	active transmembrane transporter activity	69/3407	457/18639	0.150984682713348	0.82600631085826	0.969611203737125	1
GO:0005044	scavenger receptor activity	2/3407	27/18639	0.0740740740740741	0.405244105273457	0.96984529880765	1
GO:0023026	MHC class II protein complex binding	2/3407	27/18639	0.0740740740740741	0.405244105273457	0.96984529880765	1
GO:0004879	nuclear receptor activity	6/3407	59/18639	0.101694915254237	0.556352076731356	0.970557035826707	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	6/3407	59/18639	0.101694915254237	0.556352076731356	0.970557035826707	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	24/3407	181/18639	0.132596685082873	0.725409337616574	0.971948651388685	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/3407	52/18639	0.0961538461538462	0.526038021268429	0.972418818314959	1
GO:0050840	extracellular matrix binding	7/3407	67/18639	0.104477611940299	0.571575641020025	0.972797501023269	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/3407	18/18639	0.0555555555555556	0.303933078955092	0.973623335953115	1
GO:0005372	water transmembrane transporter activity	1/3407	18/18639	0.0555555555555556	0.303933078955092	0.973623335953115	1
GO:0016854	racemase and epimerase activity	1/3407	18/18639	0.0555555555555556	0.303933078955092	0.973623335953115	1
GO:0031690	adrenergic receptor binding	1/3407	18/18639	0.0555555555555556	0.303933078955092	0.973623335953115	1
GO:0034185	apolipoprotein binding	1/3407	18/18639	0.0555555555555556	0.303933078955092	0.973623335953115	1
GO:0140375	immune receptor activity	20/3407	156/18639	0.128205128205128	0.701384028357906	0.973881471311068	1
GO:0098531	ligand-modulated transcription factor activity	6/3407	60/18639	0.1	0.547079542119166	0.973991024180263	1
GO:0051119	sugar transmembrane transporter activity	2/3407	28/18639	0.0714285714285714	0.39077110151369	0.974580822330334	1
GO:0005253	monoatomic anion channel activity	12/3407	103/18639	0.116504854368932	0.637374223828155	0.974909392144036	1
GO:0044183	protein folding chaperone	8/3407	75/18639	0.106666666666667	0.583551511593777	0.975086652828789	1
GO:0019955	cytokine binding	18/3407	144/18639	0.125	0.683849427648958	0.976279966067817	1
GO:0015245	fatty acid transmembrane transporter activity	1/3407	19/18639	0.0526315789473684	0.287936601115351	0.978449354663589	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/3407	19/18639	0.0526315789473684	0.287936601115351	0.978449354663589	1
GO:0030506	ankyrin binding	1/3407	19/18639	0.0526315789473684	0.287936601115351	0.978449354663589	1
GO:0031420	alkali metal ion binding	1/3407	19/18639	0.0526315789473684	0.287936601115351	0.978449354663589	1
GO:0042834	peptidoglycan binding	1/3407	19/18639	0.0526315789473684	0.287936601115351	0.978449354663589	1
GO:0099589	serotonin receptor activity	1/3407	19/18639	0.0526315789473684	0.287936601115351	0.978449354663589	1
GO:0004181	metallocarboxypeptidase activity	2/3407	29/18639	0.0689655172413793	0.377296235944253	0.978593253009932	1
GO:0005416	amino acid:monoatomic cation symporter activity	2/3407	29/18639	0.0689655172413793	0.377296235944253	0.978593253009932	1
GO:0008013	beta-catenin binding	12/3407	106/18639	0.113207547169811	0.619335330700943	0.981423409188404	1
GO:0033612	receptor serine/threonine kinase binding	2/3407	30/18639	0.0666666666666667	0.364719694746111	0.981988626553372	1
GO:0031418	L-ascorbic acid binding	1/3407	20/18639	0.05	0.273539771059583	0.982392590359677	1
GO:0016209	antioxidant activity	9/3407	86/18639	0.104651162790698	0.572525102217732	0.983776436735159	1
GO:0033218	amide binding	33/3407	247/18639	0.133603238866397	0.73091598744666	0.984780312119367	1
GO:0005248	voltage-gated sodium channel activity	1/3407	21/18639	0.0476190476190476	0.260514067675794	0.985614484373565	1
GO:0015125	bile acid transmembrane transporter activity	1/3407	21/18639	0.0476190476190476	0.260514067675794	0.985614484373565	1
GO:0019200	carbohydrate kinase activity	1/3407	21/18639	0.0476190476190476	0.260514067675794	0.985614484373565	1
GO:0051428	peptide hormone receptor binding	1/3407	21/18639	0.0476190476190476	0.260514067675794	0.985614484373565	1
GO:0004601	peroxidase activity	5/3407	57/18639	0.087719298245614	0.479894335192251	0.985910935202414	1
GO:0015171	amino acid transmembrane transporter activity	11/3407	102/18639	0.107843137254902	0.589987741501062	0.986470708687488	1
GO:0008093	cytoskeletal anchor activity	1/3407	22/18639	0.0454545454545455	0.248672519145076	0.988246961102497	1
GO:0016881	acid-amino acid ligase activity	1/3407	22/18639	0.0454545454545455	0.248672519145076	0.988246961102497	1
GO:0048029	monosaccharide binding	7/3407	74/18639	0.0945945945945946	0.51750767497759	0.98840870675338	1
GO:0042056	chemoattractant activity	3/3407	42/18639	0.0714285714285714	0.39077110151369	0.988943332013666	1
GO:0070888	E-box binding	5/3407	59/18639	0.0847457627118644	0.463626730609463	0.989311740003389	1
GO:0031681	G-protein beta-subunit binding	1/3407	23/18639	0.0434782608695652	0.237860670486594	0.990397823407046	1
GO:0030246	carbohydrate binding	37/3407	280/18639	0.132142857142857	0.722926537800327	0.991028053376821	1
GO:0015291	secondary active transmembrane transporter activity	38/3407	287/18639	0.132404181184669	0.724356188171719	0.991398769615737	1
GO:0030547	signaling receptor inhibitor activity	3/3407	44/18639	0.0681818181818182	0.373008778717613	0.991973070254664	1
GO:0005540	hyaluronic acid binding	1/3407	24/18639	0.0416666666666667	0.227949809216319	0.992155162021797	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/3407	24/18639	0.0416666666666667	0.227949809216319	0.992155162021797	1
GO:0005343	organic acid:sodium symporter activity	2/3407	35/18639	0.0571428571428571	0.312616881210952	0.992495049280694	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/3407	25/18639	0.04	0.218831816847667	0.993590959120467	1
GO:0030280	structural constituent of skin epidermis	2/3407	37/18639	0.0540540540540541	0.295718671415766	0.994737786478965	1
GO:0019865	immunoglobulin binding	1/3407	26/18639	0.0384615384615385	0.210415208507372	0.994764033273071	1
GO:0005506	iron ion binding	17/3407	154/18639	0.11038961038961	0.603918975066612	0.99500749498261	1
GO:0015085	calcium ion transmembrane transporter activity	16/3407	147/18639	0.108843537414966	0.595460726116099	0.995019820447545	1
GO:0170055	lipid transmembrane transporter activity	4/3407	56/18639	0.0714285714285714	0.39077110151369	0.995108046036326	1
GO:0008514	organic anion transmembrane transporter activity	34/3407	269/18639	0.12639405204461	0.691476001191511	0.995223753321268	1
GO:0008395	steroid hydroxylase activity	1/3407	27/18639	0.037037037037037	0.202622052636728	0.995722446137125	1
GO:0008188	neuropeptide receptor activity	3/3407	48/18639	0.0625	0.341924713824479	0.995811518598729	1
GO:0004497	monooxygenase activity	10/3407	106/18639	0.0943396226415094	0.516112775584119	0.996272811008208	1
GO:0046625	sphingolipid binding	1/3407	28/18639	0.0357142857142857	0.195385550756845	0.99650546924108	1
GO:0015459	potassium channel regulator activity	4/3407	59/18639	0.0677966101694915	0.37090138448757	0.996916230693254	1
GO:0015144	carbohydrate transmembrane transporter activity	2/3407	40/18639	0.05	0.273539771059583	0.996923952071822	1
GO:0140662	ATP-dependent protein folding chaperone	2/3407	40/18639	0.05	0.273539771059583	0.996923952071822	1
GO:0008236	serine-type peptidase activity	22/3407	194/18639	0.11340206185567	0.620399480753694	0.996999086462662	1
GO:0015294	solute:monoatomic cation symporter activity	11/3407	116/18639	0.0948275862068965	0.518782324423347	0.997219978145892	1
GO:0005262	calcium channel activity	13/3407	131/18639	0.099236641221374	0.542903362408333	0.997259342137939	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/3407	60/18639	0.0666666666666667	0.364719694746111	0.99735992343199	1
GO:0015293	symporter activity	15/3407	146/18639	0.102739726027397	0.562068022725171	0.997380347485247	1
GO:0008227	G protein-coupled amine receptor activity	2/3407	41/18639	0.0487804878048781	0.266868069326423	0.997430761919723	1
GO:0005010	insulin-like growth factor receptor activity	3/3407	51/18639	0.0588235294117647	0.321811495364216	0.997448495216544	1
GO:0048019	receptor antagonist activity	1/3407	30/18639	0.0333333333333333	0.182359847373055	0.997667831411265	1
GO:0004252	serine-type endopeptidase activity	19/3407	176/18639	0.107954545454545	0.590597232969555	0.997742514495568	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/3407	70/18639	0.0714285714285714	0.39077110151369	0.99780785909104	1
GO:0017171	serine hydrolase activity	22/3407	198/18639	0.111111111111111	0.607866157910185	0.99794894134443	1
GO:0005184	neuropeptide hormone activity	1/3407	31/18639	0.032258064516129	0.176477271651344	0.998094812892367	1
GO:0017147	Wnt-protein binding	1/3407	31/18639	0.032258064516129	0.176477271651344	0.998094812892367	1
GO:0008509	monoatomic anion transmembrane transporter activity	15/3407	149/18639	0.100671140939597	0.55075121689849	0.99810902199308	1
GO:0017046	peptide hormone binding	3/3407	53/18639	0.0566037735849057	0.309667665350472	0.998172563887967	1
GO:0160041	neuropeptide activity	1/3407	32/18639	0.03125	0.17096235691224	0.998443639874079	1
GO:0019838	growth factor binding	13/3407	136/18639	0.0955882352941176	0.52294367996685	0.998450666931563	1
GO:0001216	DNA-binding transcription activator activity	66/3407	491/18639	0.134419551934827	0.735381869243686	0.998505458796631	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/3407	44/18639	0.0454545454545455	0.248672519145076	0.998507269476052	1
GO:0046906	tetrapyrrole binding	15/3407	152/18639	0.0986842105263158	0.539881127091283	0.998642493212756	1
GO:0019843	rRNA binding	4/3407	65/18639	0.0615384615384615	0.336664333611795	0.998798497297156	1
GO:0003735	structural constituent of ribosome	18/3407	175/18639	0.102857142857143	0.562710386179714	0.998801260445127	1
GO:0004866	endopeptidase inhibitor activity	16/3407	161/18639	0.0993788819875776	0.543681532540786	0.998869564913475	1
GO:0019825	oxygen binding	1/3407	34/18639	0.0294117647058824	0.160905747682108	0.9989614215085	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/3407	46/18639	0.0434782608695652	0.237860670486594	0.998962945436068	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	64/3407	484/18639	0.132231404958678	0.723410964785675	0.998981915557858	1
GO:0016500	protein-hormone receptor activity	4/3407	67/18639	0.0597014925373134	0.326614652011443	0.999127041359034	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/3407	47/18639	0.0425531914893617	0.232799805157092	0.999136137557792	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/3407	36/18639	0.0277777777777778	0.151966539477546	0.999306977040588	1
GO:0019199	transmembrane receptor protein kinase activity	5/3407	78/18639	0.0641025641025641	0.350692014178953	0.999345923199315	1
GO:0046943	carboxylic acid transmembrane transporter activity	19/3407	188/18639	0.101063829787234	0.552899537248094	0.999350499132317	1
GO:0005342	organic acid transmembrane transporter activity	19/3407	189/18639	0.100529100529101	0.54997414287112	0.999416544695667	1
GO:0005006	epidermal growth factor receptor activity	2/3407	50/18639	0.04	0.218831816847667	0.999501823979317	1
GO:0030414	peptidase inhibitor activity	16/3407	169/18639	0.0946745562130177	0.51794512863353	0.999539677821848	1
GO:0005030	neurotrophin receptor activity	2/3407	51/18639	0.0392156862745098	0.214540996909477	0.999585633316573	1
GO:0071855	neuropeptide receptor binding	1/3407	40/18639	0.025	0.136769885529792	0.999691467151421	1
GO:0005254	chloride channel activity	5/3407	83/18639	0.0602409638554217	0.329565989228413	0.999698927732828	1
GO:0020037	heme binding	12/3407	142/18639	0.0845070422535211	0.462320739819014	0.999704449709883	1
GO:1901681	sulfur compound binding	30/3407	275/18639	0.109090909090909	0.596814045948182	0.999731224267398	1
GO:0001664	G protein-coupled receptor binding	33/3407	297/18639	0.111111111111111	0.607866157910185	0.99975802112356	1
GO:0005125	cytokine activity	24/3407	234/18639	0.102564102564103	0.561107222686325	0.999769714735205	1
GO:0005201	extracellular matrix structural constituent	15/3407	168/18639	0.0892857142857143	0.488463876892113	0.999787194933745	1
GO:0008083	growth factor activity	14/3407	162/18639	0.0864197530864197	0.472784789485699	0.999827686980023	1
GO:0015370	solute:sodium symporter activity	4/3407	79/18639	0.0506329113924051	0.277002299807173	0.999877382747671	1
GO:0015103	inorganic anion transmembrane transporter activity	14/3407	165/18639	0.0848484848484849	0.464188702404141	0.999881197872506	1
GO:0015108	chloride transmembrane transporter activity	8/3407	121/18639	0.0661157024793388	0.361705482392837	0.999943501642345	1
GO:0003730	mRNA 3'-UTR binding	26/3407	262/18639	0.099236641221374	0.542903362408333	0.999944370994349	1
GO:0005004	GPI-linked ephrin receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0005008	hepatocyte growth factor receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0005009	insulin receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0005011	macrophage colony-stimulating factor receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0005020	stem cell factor receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0008288	boss receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0036332	placental growth factor receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0038062	protein tyrosine kinase collagen receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0060175	brain-derived neurotrophic factor receptor activity	1/3407	49/18639	0.0204081632653061	0.111648886146769	0.999950083854492	1
GO:0004867	serine-type endopeptidase inhibitor activity	5/3407	95/18639	0.0526315789473684	0.287936601115351	0.999955605575201	1
GO:0005007	fibroblast growth factor receptor activity	1/3407	50/18639	0.02	0.109415908423833	0.99995923201521	1
GO:0005017	platelet-derived growth factor receptor activity	1/3407	50/18639	0.02	0.109415908423833	0.99995923201521	1
GO:0005019	platelet-derived growth factor beta-receptor activity	1/3407	50/18639	0.02	0.109415908423833	0.99995923201521	1
GO:0005021	vascular endothelial growth factor receptor activity	1/3407	51/18639	0.0196078431372549	0.107270498454739	0.999966703989183	1
GO:0005272	sodium channel activity	1/3407	51/18639	0.0196078431372549	0.107270498454739	0.999966703989183	1
GO:0099094	ligand-gated monoatomic cation channel activity	9/3407	136/18639	0.0661764705882353	0.362037932284742	0.999977237599675	1
GO:0005003	ephrin receptor activity	1/3407	53/18639	0.0188679245283019	0.103222555116824	0.999977791338075	1
GO:0005005	transmembrane-ephrin receptor activity	1/3407	53/18639	0.0188679245283019	0.103222555116824	0.999977791338075	1
GO:0038064	collagen receptor activity	1/3407	53/18639	0.0188679245283019	0.103222555116824	0.999977791338075	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/3407	53/18639	0.0188679245283019	0.103222555116824	0.999977791338075	1
GO:0098960	postsynaptic neurotransmitter receptor activity	2/3407	69/18639	0.0289855072463768	0.158573780324396	0.999985666132541	1
GO:0008528	G protein-coupled peptide receptor activity	7/3407	122/18639	0.0573770491803279	0.313898097937227	0.999987544208485	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/3407	56/18639	0.0178571428571429	0.0976927753784226	0.99998790298159	1
GO:0015079	potassium ion transmembrane transporter activity	11/3407	160/18639	0.06875	0.376117185206927	0.999991243375669	1
GO:0022843	voltage-gated monoatomic cation channel activity	9/3407	143/18639	0.0629370629370629	0.344315795739336	0.999991845122884	1
GO:0030594	neurotransmitter receptor activity	4/3407	97/18639	0.0412371134020619	0.225599811183161	0.999994252202881	1
GO:0001653	peptide receptor activity	7/3407	128/18639	0.0546875	0.299184124596419	0.999995118152567	1
GO:0005249	voltage-gated potassium channel activity	4/3407	98/18639	0.0408163265306122	0.223297772293537	0.999995166596109	1
GO:0005244	voltage-gated monoatomic ion channel activity	12/3407	173/18639	0.069364161849711	0.379477139042196	0.999995309104822	1
GO:0003823	antigen binding	12/3407	174/18639	0.0689655172413793	0.377296235944253	0.999995923110156	1
GO:0022832	voltage-gated channel activity	12/3407	175/18639	0.0685714285714286	0.375140257453143	0.999996458041108	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/3407	63/18639	0.0158730158730159	0.0868380225585978	0.999997070061059	1
GO:0022835	transmitter-gated channel activity	1/3407	63/18639	0.0158730158730159	0.0868380225585978	0.999997070061059	1
GO:0008201	heparin binding	11/3407	172/18639	0.063953488372093	0.349876451355281	0.999998435516791	1
GO:0015081	sodium ion transmembrane transporter activity	10/3407	164/18639	0.0609756097560976	0.333585086658028	0.999998634030342	1
GO:0046873	metal ion transmembrane transporter activity	47/3407	450/18639	0.104444444444444	0.571394188435574	0.999998751206058	1
GO:0005179	hormone activity	6/3407	132/18639	0.0454545454545455	0.248672519145076	0.999999478037881	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/3407	73/18639	0.0136986301369863	0.0749424030300228	0.999999613926785	1
GO:0005267	potassium channel activity	5/3407	124/18639	0.0403225806451613	0.22059658956418	0.999999653800097	1
GO:0015276	ligand-gated monoatomic ion channel activity	11/3407	186/18639	0.0591397849462366	0.323541664694131	0.999999802770955	1
GO:0022834	ligand-gated channel activity	11/3407	188/18639	0.0585106382978723	0.320099732091002	0.999999853999549	1
GO:0005539	glycosaminoglycan binding	15/3407	242/18639	0.0619834710743802	0.339098889743285	0.999999989813753	1
GO:0005216	monoatomic ion channel activity	40/3407	448/18639	0.0892857142857143	0.488463876892113	0.999999993728918	1
GO:0005261	monoatomic cation channel activity	26/3407	341/18639	0.0762463343108504	0.417128096630449	0.999999995477623	1
GO:0030527	structural constituent of chromatin	1/3407	98/18639	0.0102040816326531	0.0558244430733843	0.99999999757955	1
GO:0022836	gated channel activity	21/3407	318/18639	0.0660377358490566	0.361278942908883	0.999999999647776	1
GO:0004984	olfactory receptor activity	1/3407	419/18639	0.00238663484486874	0.0130567909813644	1	1
GO:0030371	translation repressor activity	8/3407	329/18639	0.0243161094224924	0.133028460089767	1	1
GO:0045182	translation regulator activity	11/3407	356/18639	0.0308988764044944	0.169041431553675	1	1