ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 106/1975 495/18639 0.214141414141414 2.02095281933257 8.28050393105583e-13 9.8786411897496e-10 GO:0140297 DNA-binding transcription factor binding 101/1975 488/18639 0.206967213114754 1.95324652417514 2.3951285784732e-11 1.42869419705927e-08 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 73/1975 349/18639 0.209169054441261 1.97402633201552 8.88441538387093e-09 3.53303585098601e-06 GO:0003713 transcription coactivator activity 58/1975 256/18639 0.2265625 2.13817642405063 1.54991521849502e-08 4.6226221391614e-06 GO:0001221 transcription coregulator binding 32/1975 115/18639 0.278260869565217 2.62607815079802 2.09091207180361e-07 4.98891620332341e-05 GO:0106310 protein serine kinase activity 70/1975 361/18639 0.193905817174515 1.82998001332445 3.94227535574115e-07 7.83855749899866e-05 GO:0001046 core promoter sequence-specific DNA binding 17/1975 44/18639 0.386363636363636 3.64629459148446 1.03811558161804e-06 0.000176924555552904 GO:0004674 protein serine/threonine kinase activity 78/1975 433/18639 0.18013856812933 1.70005203613296 1.84784910045369e-06 0.000275560497105157 GO:0003714 transcription corepressor activity 43/1975 204/18639 0.21078431372549 1.98927029039464 7.84747985317267e-06 0.00104022705164833 GO:0016922 nuclear receptor binding 32/1975 137/18639 0.233576642335766 2.2043721703779 1.27598387865939e-05 0.00152224876724065 GO:0004842 ubiquitin-protein transferase activity 76/1975 449/18639 0.169265033407572 1.59743339629557 2.47356485727138e-05 0.00230960124839973 GO:0019787 ubiquitin-like protein transferase activity 80/1975 479/18639 0.167014613778706 1.57619513226395 2.49311062785815e-05 0.00230960124839973 GO:0001223 transcription coactivator binding 15/1975 44/18639 0.340909090909091 3.21731875719217 2.61831694759415e-05 0.00230960124839973 GO:0019208 phosphatase regulator activity 28/1975 117/18639 0.239316239316239 2.2585394352483 2.71034513642886e-05 0.00230960124839973 GO:0045296 cadherin binding 60/1975 334/18639 0.179640718562874 1.69535359660426 2.99936250734205e-05 0.00238549298083938 GO:0043022 ribosome binding 27/1975 112/18639 0.241071428571429 2.27510397830018 3.26051024962838e-05 0.00243111795487916 GO:0044389 ubiquitin-like protein ligase binding 58/1975 322/18639 0.180124223602484 1.69991666011479 3.73145387885155e-05 0.00261860263380582 GO:0031625 ubiquitin protein ligase binding 55/1975 302/18639 0.182119205298013 1.71874423673401 4.29121081173966e-05 0.00284411916578079 GO:0035259 nuclear glucocorticoid receptor binding 7/1975 12/18639 0.583333333333333 5.50518987341772 7.2565501317194e-05 0.00451018872207521 GO:0140296 general transcription initiation factor binding 16/1975 53/18639 0.30188679245283 2.84904705039408 7.71341039686068e-05 0.00451018872207521 GO:0140416 transcription regulator inhibitor activity 12/1975 33/18639 0.363636363636364 3.43180667433832 8.16125634063596e-05 0.00451018872207521 GO:0016755 aminoacyltransferase activity 80/1975 496/18639 0.161290322580645 1.52217231523071 8.49151294384641e-05 0.00451018872207521 GO:0070063 RNA polymerase binding 17/1975 59/18639 0.288135593220339 2.71927054280197 8.92251541320448e-05 0.00451018872207521 GO:0043021 ribonucleoprotein complex binding 36/1975 177/18639 0.203389830508475 1.91948508903669 9.07330505698281e-05 0.00451018872207521 GO:0001222 transcription corepressor binding 15/1975 49/18639 0.306122448979592 2.88902092482563 0.000107588550996653 0.00513412565356028 GO:0017025 TBP-class protein binding 10/1975 25/18639 0.4 3.77498734177215 0.000127232815229902 0.00567250277491942 GO:0005518 collagen binding 19/1975 72/18639 0.263888888888889 2.49044303797468 0.000129941604081017 0.00567250277491942 GO:0043995 histone H4K5 acetyltransferase activity 11/1975 30/18639 0.366666666666667 3.46040506329114 0.000148087303533749 0.00567250277491942 GO:0043996 histone H4K8 acetyltransferase activity 11/1975 30/18639 0.366666666666667 3.46040506329114 0.000148087303533749 0.00567250277491942 GO:0043997 histone H4K12 acetyltransferase activity 11/1975 30/18639 0.366666666666667 3.46040506329114 0.000148087303533749 0.00567250277491942 GO:0050840 extracellular matrix binding 18/1975 67/18639 0.26865671641791 2.53543925939921 0.000151292090079842 0.00567250277491942 GO:0010485 histone H4 acetyltransferase activity 12/1975 35/18639 0.342857142857143 3.2357034358047 0.000156909129566086 0.00567250277491942 GO:0061631 ubiquitin conjugating enzyme activity 12/1975 35/18639 0.342857142857143 3.2357034358047 0.000156909129566086 0.00567250277491942 GO:0140857 histone H3T45 kinase activity 45/1975 246/18639 0.182926829268293 1.7263661623958 0.000184179744618142 0.00646254221557188 GO:0005096 GTPase activator activity 48/1975 271/18639 0.177121771217712 1.67158111074782 0.000252241226240141 0.0069856330925676 GO:0060589 nucleoside-triphosphatase regulator activity 77/1975 490/18639 0.157142857142857 1.48303074141049 0.000263838757625441 0.0069856330925676 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 44/1975 243/18639 0.181069958847737 1.70884200656353 0.000272524561798921 0.0069856330925676 GO:0019888 protein phosphatase regulator activity 24/1975 107/18639 0.224299065420561 2.11681533183485 0.000285622499761793 0.0069856330925676 GO:0032182 ubiquitin-like protein binding 26/1975 120/18639 0.216666666666667 2.04478481012658 0.000292286144530559 0.0069856330925676 GO:0004676 3-phosphoinositide-dependent protein kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0004711 ribosomal protein S6 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0035175 histone H3S10 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0035979 histone H2AXS139 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0044022 histone H3S28 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0044023 histone H4S1 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0044024 histone H2AS1 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0044025 histone H2BS14 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0072354 histone H3T3 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0072371 histone H2AS121 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0072518 Rho-dependent protein serine/threonine kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0140823 histone H2BS36 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0140855 histone H3S57 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0140995 histone H2A kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0140997 histone H4 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0140998 histone H2B kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:1990244 histone H2AT120 kinase activity 44/1975 245/18639 0.179591836734694 1.6948922758977 0.000327909013565621 0.0069856330925676 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 27/1975 128/18639 0.2109375 1.99071598101266 0.000356309817375843 0.00738870931450286 GO:0004677 DNA-dependent protein kinase activity 44/1975 246/18639 0.178861788617886 1.68800246989812 0.000359216379078932 0.00738870931450286 GO:0036408 histone H3K14 acetyltransferase activity 10/1975 28/18639 0.357142857142857 3.37052441229656 0.00037931071689743 0.0074260324708233 GO:0001098 basal transcription machinery binding 16/1975 60/18639 0.266666666666667 2.5166582278481 0.000379704929354754 0.0074260324708233 GO:0001099 basal RNA polymerase II transcription machinery binding 16/1975 60/18639 0.266666666666667 2.5166582278481 0.000379704929354754 0.0074260324708233 GO:0035402 histone H3T11 kinase activity 44/1975 247/18639 0.178137651821862 1.68116845180136 0.00039317230827713 0.00744531053610501 GO:0035403 histone H3T6 kinase activity 44/1975 247/18639 0.178137651821862 1.68116845180136 0.00039317230827713 0.00744531053610501 GO:0030695 GTPase regulator activity 76/1975 489/18639 0.155419222903885 1.46676399782558 0.000404072283245179 0.00753215990486716 GO:0004679 AMP-activated protein kinase activity 44/1975 248/18639 0.17741935483871 1.67438954675378 0.000429969075195526 0.00789158625705018 GO:0046332 SMAD binding 19/1975 79/18639 0.240506329113924 2.26977087005288 0.000473828431965491 0.00856480786870955 GO:0043998 histone H2A acetyltransferase activity 9/1975 24/18639 0.375 3.53905063291139 0.000490634520273897 0.00873622362219044 GO:0141003 histone H2AX kinase activity 58/1975 354/18639 0.163841807909605 1.54625187727955 0.000508229307158866 0.00891643475647834 GO:0010484 histone H3 acetyltransferase activity 10/1975 29/18639 0.344827586206897 3.2542994325622 0.000524388100039929 0.009066594251415 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 17/1975 68/18639 0.25 2.35936708860759 0.0005740233852503 0.00978299855148011 GO:0140996 histone H3 kinase activity 58/1975 357/18639 0.162464985994398 1.5332581640251 0.000629809561165489 0.0105825747390201 GO:0035173 histone kinase activity 58/1975 360/18639 0.161111111111111 1.52048101265823 0.000776754334263148 0.0128703877885547 GO:0061650 ubiquitin-like protein conjugating enzyme activity 12/1975 41/18639 0.292682926829268 2.76218585983328 0.000813237940485057 0.0132903131917626 GO:0000993 RNA polymerase II complex binding 11/1975 36/18639 0.305555555555556 2.88367088607595 0.000895157927186231 0.0141665468769697 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 8/1975 21/18639 0.380952380952381 3.595226039783 0.00089633748247262 0.0141665468769697 GO:0061733 protein-lysine-acetyltransferase activity 13/1975 47/18639 0.276595744680851 2.61036358739564 0.000902479096940232 0.0141665468769697 GO:0034212 protein N-acetyltransferase activity 14/1975 53/18639 0.264150943396226 2.49291616909482 0.000957740929136415 0.0147428180802574 GO:0070412 R-SMAD binding 9/1975 26/18639 0.346153846153846 3.26681596884129 0.000963905959983299 0.0147428180802574 GO:0004402 histone acetyltransferase activity 12/1975 42/18639 0.285714285714286 2.69641952983725 0.00103012716886864 0.0153277267110395 GO:0043175 RNA polymerase core enzyme binding 12/1975 42/18639 0.285714285714286 2.69641952983725 0.00103012716886864 0.0153277267110395 GO:0061659 ubiquitin-like protein ligase activity 59/1975 372/18639 0.158602150537634 1.49680277664353 0.00104069225783252 0.0153277267110395 GO:0042805 actinin binding 11/1975 37/18639 0.297297297297297 2.80573383510092 0.00115335619186725 0.0157269733364387 GO:0098531 ligand-modulated transcription factor activity 15/1975 60/18639 0.25 2.35936708860759 0.00118581702493854 0.0157269733364387 GO:0022853 active monoatomic ion transmembrane transporter activity 24/1975 118/18639 0.203389830508475 1.91948508903669 0.00126248801825931 0.0157269733364387 GO:0032931 histone H3K56 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0043992 histone H3K9 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0043993 histone H3K18 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0043994 histone H3K23 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0043999 histone H2AK5 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0044012 histone H2AK9 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0044014 histone H2BK5 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0044015 histone H2BK12 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0044016 histone H3K4 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0044017 histone H3K27 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0044018 histone H3K36 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0046972 histone H4K16 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0140908 histone H3K122 acetyltransferase activity 8/1975 22/18639 0.363636363636364 3.43180667433832 0.0012787228949158 0.0157269733364387 GO:0019902 phosphatase binding 34/1975 190/18639 0.178947368421053 1.68881012658228 0.00156996870166514 0.0191119659294541 GO:0043130 ubiquitin binding 21/1975 100/18639 0.21 1.98186835443038 0.00162875597617681 0.019627332116959 GO:0003779 actin binding 67/1975 443/18639 0.151241534988713 1.42733720033146 0.00175882206061401 0.0209827471831251 GO:0044013 histone H2B acetyltransferase activity 8/1975 23/18639 0.347826086956522 3.28259768849752 0.00178029950617769 0.0210286862462374 GO:0003727 single-stranded RNA binding 19/1975 89/18639 0.213483146067416 2.01474043521547 0.00217521021713626 0.0254414293043487 GO:0061630 ubiquitin protein ligase activity 55/1975 353/18639 0.155807365439093 1.47042708071861 0.00225652419719246 0.0261362462839865 GO:0043236 laminin binding 9/1975 29/18639 0.310344827586207 2.92886948930598 0.00230540484037056 0.0264456536015585 GO:0030276 clathrin binding 12/1975 46/18639 0.260869565217391 2.46194826637314 0.00243157400839797 0.0276273123049408 GO:0004879 nuclear receptor activity 14/1975 59/18639 0.23728813559322 2.2393992705428 0.00289371821266254 0.0325679795066643 GO:0051371 muscle alpha-actinin binding 6/1975 15/18639 0.4 3.77498734177215 0.00301656445874458 0.0336332841054419 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 43/1975 268/18639 0.16044776119403 1.51422066880786 0.00374306776195611 0.0409788637557069 GO:0000287 magnesium ion binding 38/1975 230/18639 0.165217391304348 1.55923390203632 0.00374408730039569 0.0409788637557069 GO:0019838 growth factor binding 25/1975 136/18639 0.183823529411765 1.73482874162323 0.00427929446578875 0.0460240332719869 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 70/1975 484/18639 0.144628099173554 1.36492310911183 0.00436284564342656 0.0460240332719869 GO:0001217 DNA-binding transcription repressor activity 44/1975 278/18639 0.158273381294964 1.49370002731992 0.00438035397167043 0.0460240332719869 GO:0030275 LRR domain binding 6/1975 16/18639 0.375 3.53905063291139 0.00439793779799371 0.0460240332719869 GO:0034450 ubiquitin-ubiquitin ligase activity 6/1975 16/18639 0.375 3.53905063291139 0.00439793779799371 0.0460240332719869 GO:0008080 N-acetyltransferase activity 15/1975 69/18639 0.217391304347826 2.05162355531095 0.00509056309009075 0.0528090588389414 GO:0016407 acetyltransferase activity 19/1975 96/18639 0.197916666666667 1.86783227848101 0.00527238693660578 0.0542237725462991 GO:0017166 vinculin binding 5/1975 12/18639 0.416666666666667 3.93227848101266 0.00555364113234776 0.056148253143143 GO:0035497 cAMP response element binding 5/1975 12/18639 0.416666666666667 3.93227848101266 0.00555364113234776 0.056148253143143 GO:0071889 14-3-3 protein binding 9/1975 33/18639 0.272727272727273 2.57385500575374 0.00602090082287081 0.0602974861013877 GO:0031267 small GTPase binding 44/1975 283/18639 0.15547703180212 1.46730956747327 0.0060651285265436 0.0602974861013877 GO:0001216 DNA-binding transcription activator activity 70/1975 491/18639 0.142566191446029 1.34546392018356 0.00612961893109572 0.0604350031801421 GO:0046965 nuclear retinoid X receptor binding 6/1975 17/18639 0.352941176470588 3.3308711839166 0.00619476901584106 0.0605767166876917 GO:0051117 ATPase binding 17/1975 84/18639 0.202380952380952 1.90996383363472 0.00639817413081801 0.0620570873013486 GO:0045499 chemorepellent activity 8/1975 28/18639 0.285714285714286 2.69641952983725 0.00698238858306584 0.0661110284095043 GO:0051019 mitogen-activated protein kinase binding 8/1975 28/18639 0.285714285714286 2.69641952983725 0.00698238858306584 0.0661110284095043 GO:0051393 alpha-actinin binding 8/1975 28/18639 0.285714285714286 2.69641952983725 0.00698238858306584 0.0661110284095043 GO:0042826 histone deacetylase binding 23/1975 127/18639 0.181102362204724 1.70914781221968 0.00717917614156854 0.067439032573947 GO:0031593 polyubiquitin modification-dependent protein binding 13/1975 59/18639 0.220338983050847 2.07944217978974 0.00781614937153731 0.0728489546894064 GO:0140030 modification-dependent protein binding 29/1975 173/18639 0.167630057803468 1.58200336577157 0.00849842893931164 0.0785939978651069 GO:0017080 sodium channel regulator activity 10/1975 41/18639 0.24390243902439 2.30182154986107 0.00903624585125349 0.0829249330811185 GO:0004721 phosphoprotein phosphatase activity 29/1975 175/18639 0.165714285714286 1.56392332730561 0.00993656797594974 0.0863729956588777 GO:0050699 WW domain binding 7/1975 24/18639 0.291666666666667 2.75259493670886 0.0101261157456598 0.0863729956588777 GO:0033192 calmodulin-dependent protein phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:0140791 histone H2AXS140 phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:1990439 MAP kinase serine/threonine phosphatase activity 16/1975 81/18639 0.197530864197531 1.86419127988748 0.0101359760203209 0.0863729956588777 GO:0035925 mRNA 3'-UTR AU-rich region binding 8/1975 30/18639 0.266666666666667 2.5166582278481 0.0108644729778496 0.0908419030321391 GO:0051721 protein phosphatase 2A binding 8/1975 30/18639 0.266666666666667 2.5166582278481 0.0108644729778496 0.0908419030321391 GO:1990841 promoter-specific chromatin binding 14/1975 68/18639 0.205882352941176 1.94300819061802 0.0108888450407342 0.0908419030321391 GO:0003725 double-stranded RNA binding 15/1975 75/18639 0.2 1.88749367088608 0.0112096802033877 0.0917997088530681 GO:0019003 GDP binding 15/1975 75/18639 0.2 1.88749367088608 0.0112096802033877 0.0917997088530681 GO:0140313 molecular sequestering activity 12/1975 55/18639 0.218181818181818 2.05908400460299 0.0112351614915264 0.0917997088530681 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 16/1975 82/18639 0.195121951219512 1.84145723988885 0.0113883964042364 0.0917997088530681 GO:0033549 MAP kinase phosphatase activity 16/1975 82/18639 0.195121951219512 1.84145723988885 0.0113883964042364 0.0917997088530681 GO:0004713 protein tyrosine kinase activity 24/1975 140/18639 0.171428571428571 1.61785171790235 0.0120160674421022 0.0962091842847515 GO:0048156 tau protein binding 10/1975 43/18639 0.232558139534884 2.19476008242567 0.0127229674129823 0.0985520064986307 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 16/1975 83/18639 0.192771084337349 1.81927100808296 0.0127593955039388 0.0985520064986307 GO:0004709 MAP kinase kinase kinase activity 7/1975 25/18639 0.28 2.64249113924051 0.012804326074843 0.0985520064986307 GO:0008139 nuclear localization sequence binding 7/1975 25/18639 0.28 2.64249113924051 0.012804326074843 0.0985520064986307 GO:0042974 nuclear retinoic acid receptor binding 7/1975 25/18639 0.28 2.64249113924051 0.012804326074843 0.0985520064986307 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 7/1975 25/18639 0.28 2.64249113924051 0.012804326074843 0.0985520064986307 GO:0016791 phosphatase activity 41/1975 273/18639 0.15018315018315 1.41734872722214 0.013824951714867 0.105725432024592 GO:0017018 myosin phosphatase activity 16/1975 84/18639 0.19047619047619 1.7976130198915 0.0142561534740848 0.108328605697982 GO:0043024 ribosomal small subunit binding 6/1975 20/18639 0.3 2.83124050632911 0.0147104699625067 0.111073358640952 GO:0003954 NADH dehydrogenase activity 10/1975 44/18639 0.227272727272727 2.14487917146145 0.0149427351942433 0.111545370667 GO:0051020 GTPase binding 46/1975 315/18639 0.146031746031746 1.37816998191682 0.015457990840685 0.111545370667 GO:0005528 FK506 binding 4/1975 10/18639 0.4 3.77498734177215 0.0156167746443602 0.111545370667 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 4/1975 10/18639 0.4 3.77498734177215 0.0156167746443602 0.111545370667 GO:0031434 mitogen-activated protein kinase kinase binding 4/1975 10/18639 0.4 3.77498734177215 0.0156167746443602 0.111545370667 GO:0003697 single-stranded DNA binding 21/1975 121/18639 0.173553719008264 1.6379077309342 0.0157617010632316 0.111545370667 GO:0004540 RNA nuclease activity 21/1975 121/18639 0.173553719008264 1.6379077309342 0.0157617010632316 0.111545370667 GO:0044325 transmembrane transporter binding 23/1975 136/18639 0.169117647058824 1.59604244229337 0.0160024046244649 0.111545370667 GO:0140789 histone phosphatase activity 23/1975 136/18639 0.169117647058824 1.59604244229337 0.0160024046244649 0.111545370667 GO:0004129 cytochrome-c oxidase activity 5/1975 15/18639 0.333333333333333 3.14582278481013 0.0160758015502045 0.111545370667 GO:0016846 carbon-sulfur lyase activity 5/1975 15/18639 0.333333333333333 3.14582278481013 0.0160758015502045 0.111545370667 GO:0031386 protein tag activity 5/1975 15/18639 0.333333333333333 3.14582278481013 0.0160758015502045 0.111545370667 GO:0141047 molecular tag activity 5/1975 15/18639 0.333333333333333 3.14582278481013 0.0160758015502045 0.111545370667 GO:0051059 NF-kappaB binding 8/1975 32/18639 0.25 2.35936708860759 0.0161446211992229 0.111545370667 GO:0003743 translation initiation factor activity 11/1975 51/18639 0.215686274509804 2.03553239017126 0.0161754812450889 0.111545370667 GO:0005516 calmodulin binding 32/1975 207/18639 0.154589371980676 1.4589323059989 0.0186352233841626 0.127769089064977 GO:0051010 microtubule plus-end binding 6/1975 21/18639 0.285714285714286 2.69641952983725 0.0187891205949944 0.128088119256162 GO:0042393 histone binding 37/1975 247/18639 0.149797570850202 1.41370983446933 0.0192947701547654 0.130651777296887 GO:0140311 protein sequestering activity 8/1975 33/18639 0.242424242424242 2.28787111622555 0.0193842117196555 0.130651777296887 GO:0046982 protein heterodimerization activity 52/1975 369/18639 0.140921409214092 1.32994133991973 0.0200158967379624 0.134151487687579 GO:0016251 RNA polymerase II general transcription initiation factor activity 11/1975 53/18639 0.207547169811321 1.95871984714593 0.0213018105698049 0.139404471448222 GO:0004708 MAP kinase kinase activity 5/1975 16/18639 0.3125 2.94920886075949 0.021383921437573 0.139404471448222 GO:0005159 insulin-like growth factor receptor binding 5/1975 16/18639 0.3125 2.94920886075949 0.021383921437573 0.139404471448222 GO:0008142 oxysterol binding 5/1975 16/18639 0.3125 2.94920886075949 0.021383921437573 0.139404471448222 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1975 16/18639 0.3125 2.94920886075949 0.021383921437573 0.139404471448222 GO:0030331 nuclear estrogen receptor binding 9/1975 40/18639 0.225 2.12343037974684 0.0217663247305582 0.140538639623157 GO:0015217 ADP transmembrane transporter activity 4/1975 11/18639 0.363636363636364 3.43180667433832 0.0225139296298458 0.140538639623157 GO:0032050 clathrin heavy chain binding 4/1975 11/18639 0.363636363636364 3.43180667433832 0.0225139296298458 0.140538639623157 GO:0034056 estrogen response element binding 4/1975 11/18639 0.363636363636364 3.43180667433832 0.0225139296298458 0.140538639623157 GO:0043522 leucine zipper domain binding 4/1975 11/18639 0.363636363636364 3.43180667433832 0.0225139296298458 0.140538639623157 GO:0050998 nitric-oxide synthase binding 4/1975 11/18639 0.363636363636364 3.43180667433832 0.0225139296298458 0.140538639623157 GO:0070990 snRNP binding 4/1975 11/18639 0.363636363636364 3.43180667433832 0.0225139296298458 0.140538639623157 GO:0140537 transcription regulator activator activity 4/1975 11/18639 0.363636363636364 3.43180667433832 0.0225139296298458 0.140538639623157 GO:0004722 protein serine/threonine phosphatase activity 18/1975 103/18639 0.174757281553398 1.64926631436647 0.0226181213810949 0.140538639623157 GO:0050321 tau-protein kinase activity 6/1975 22/18639 0.272727272727273 2.57385500575374 0.0235762034650196 0.145732698102427 GO:0003925 G protein activity 11/1975 54/18639 0.203703703703704 1.92244725738397 0.0242710478711397 0.149254433558091 GO:0001727 lipid kinase activity 9/1975 41/18639 0.219512195121951 2.07163939487496 0.0253466594153627 0.154278391237386 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/1975 41/18639 0.219512195121951 2.07163939487496 0.0253466594153627 0.154278391237386 GO:0019783 ubiquitin-like protein peptidase activity 21/1975 127/18639 0.165354330708661 1.56052626333101 0.0259647110719297 0.157238072633564 GO:0005092 GDP-dissociation inhibitor activity 5/1975 17/18639 0.294117647058824 2.77572598659717 0.027712734946628 0.163137963961436 GO:0008429 phosphatidylethanolamine binding 5/1975 17/18639 0.294117647058824 2.77572598659717 0.027712734946628 0.163137963961436 GO:0032183 SUMO binding 5/1975 17/18639 0.294117647058824 2.77572598659717 0.027712734946628 0.163137963961436 GO:0051787 misfolded protein binding 5/1975 17/18639 0.294117647058824 2.77572598659717 0.027712734946628 0.163137963961436 GO:1990226 histone methyltransferase binding 5/1975 17/18639 0.294117647058824 2.77572598659717 0.027712734946628 0.163137963961436 GO:0002039 p53 binding 13/1975 69/18639 0.188405797101449 1.77807374793616 0.0277594356112083 0.163137963961436 GO:0031490 chromatin DNA binding 21/1975 128/18639 0.1640625 1.54833465189873 0.0280671018851774 0.16413751249518 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/1975 29/18639 0.241379310344828 2.27800960279354 0.0286258868108523 0.165780014394887 GO:0097472 cyclin-dependent protein kinase activity 7/1975 29/18639 0.241379310344828 2.27800960279354 0.0286258868108523 0.165780014394887 GO:0005158 insulin receptor binding 6/1975 23/18639 0.260869565217391 2.46194826637314 0.0291160415751718 0.166997296149904 GO:0070577 lysine-acetylated histone binding 6/1975 23/18639 0.260869565217391 2.46194826637314 0.0291160415751718 0.166997296149904 GO:0019903 protein phosphatase binding 23/1975 144/18639 0.159722222222222 1.50737341772152 0.029592078870389 0.168915550681216 GO:0060590 ATPase regulator activity 10/1975 49/18639 0.204081632653061 1.92601394988375 0.030538067165704 0.17348530537469 GO:0005165 neurotrophin receptor binding 4/1975 12/18639 0.333333333333333 3.14582278481013 0.0309940738785948 0.173595916136918 GO:0005527 macrolide binding 4/1975 12/18639 0.333333333333333 3.14582278481013 0.0309940738785948 0.173595916136918 GO:0035197 siRNA binding 4/1975 12/18639 0.333333333333333 3.14582278481013 0.0309940738785948 0.173595916136918 GO:0008187 poly-pyrimidine tract binding 7/1975 30/18639 0.233333333333333 2.20207594936709 0.0340315344991575 0.188835444918581 GO:0015215 nucleotide transmembrane transporter activity 7/1975 30/18639 0.233333333333333 2.20207594936709 0.0340315344991575 0.188835444918581 GO:0004843 cysteine-type deubiquitinase activity 18/1975 108/18639 0.166666666666667 1.57291139240506 0.0347181510333731 0.189628242619055 GO:0004706 JUN kinase kinase kinase activity 5/1975 18/18639 0.277777777777778 2.62151898734177 0.0351133522619511 0.189628242619055 GO:0070064 proline-rich region binding 5/1975 18/18639 0.277777777777778 2.62151898734177 0.0351133522619511 0.189628242619055 GO:0070628 proteasome binding 5/1975 18/18639 0.277777777777778 2.62151898734177 0.0351133522619511 0.189628242619055 GO:0030215 semaphorin receptor binding 6/1975 24/18639 0.25 2.35936708860759 0.0354460168516758 0.189628242619055 GO:0035035 histone acetyltransferase binding 6/1975 24/18639 0.25 2.35936708860759 0.0354460168516758 0.189628242619055 GO:0050431 transforming growth factor beta binding 6/1975 24/18639 0.25 2.35936708860759 0.0354460168516758 0.189628242619055 GO:0140033 acetylation-dependent protein binding 6/1975 24/18639 0.25 2.35936708860759 0.0354460168516758 0.189628242619055 GO:0009055 electron transfer activity 19/1975 116/18639 0.163793103448276 1.54579223046704 0.0359246915996284 0.191331058385521 GO:0005048 signal sequence binding 10/1975 51/18639 0.196078431372549 1.85048399106478 0.0391875730806249 0.207781220823047 GO:0003707 nuclear steroid receptor activity 6/1975 25/18639 0.24 2.26499240506329 0.0425960244654124 0.223863688049502 GO:0019211 phosphatase activator activity 6/1975 25/18639 0.24 2.26499240506329 0.0425960244654124 0.223863688049502 GO:0005543 phospholipid binding 65/1975 497/18639 0.130784708249497 1.23427654534804 0.0431764327817128 0.225804121161363 GO:0003756 protein disulfide isomerase activity 5/1975 19/18639 0.263157894736842 2.48354430379747 0.0436217882846983 0.225804121161363 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/1975 19/18639 0.263157894736842 2.48354430379747 0.0436217882846983 0.225804121161363 GO:0045309 protein phosphorylated amino acid binding 11/1975 59/18639 0.186440677966102 1.75952799828363 0.0437223403086964 0.225804121161363 GO:0001618 virus receptor activity 14/1975 81/18639 0.172839506172839 1.63116736990155 0.0444652203295439 0.228650895918732 GO:0015399 primary active transmembrane transporter activity 25/1975 166/18639 0.150602409638554 1.42130547506482 0.045049673055077 0.230662059891446 GO:0042578 phosphoric ester hydrolase activity 49/1975 363/18639 0.134986225895317 1.27392823517104 0.0454585964617008 0.231761134952175 GO:0070717 poly-purine tract binding 7/1975 32/18639 0.21875 2.06444620253165 0.0467742252712201 0.237453832972619 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 12/1975 67/18639 0.17910447761194 1.69029283959947 0.0474563975960109 0.239896111576445 GO:0003924 GTPase activity 45/1975 331/18639 0.13595166163142 1.28303950437875 0.0483382389774037 0.243322865401023 GO:0140272 exogenous protein binding 14/1975 82/18639 0.170731707317073 1.61127508490275 0.048602714510261 0.243626211809838 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/1975 39/18639 0.205128205128205 1.93589094449854 0.0488494542893496 0.243838489402485 GO:0019955 cytokine binding 22/1975 144/18639 0.152777777777778 1.44183544303797 0.0502176202885165 0.249623420850834 GO:0140223 general transcription initiation factor activity 12/1975 68/18639 0.176470588235294 1.6654355919583 0.0522986988763722 0.257238303683278 GO:0005161 platelet-derived growth factor receptor binding 4/1975 14/18639 0.285714285714286 2.69641952983725 0.0528572212223123 0.257238303683278 GO:0005347 ATP transmembrane transporter activity 4/1975 14/18639 0.285714285714286 2.69641952983725 0.0528572212223123 0.257238303683278 GO:0008191 metalloendopeptidase inhibitor activity 4/1975 14/18639 0.285714285714286 2.69641952983725 0.0528572212223123 0.257238303683278 GO:0061665 SUMO ligase activity 4/1975 14/18639 0.285714285714286 2.69641952983725 0.0528572212223123 0.257238303683278 GO:0042288 MHC class I protein binding 5/1975 20/18639 0.25 2.35936708860759 0.0532588943920954 0.257238303683278 GO:0061608 nuclear import signal receptor activity 5/1975 20/18639 0.25 2.35936708860759 0.0532588943920954 0.257238303683278 GO:0008013 beta-catenin binding 17/1975 106/18639 0.160377358490566 1.51355624552185 0.0537561768908643 0.258593221898392 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 10/1975 54/18639 0.185185185185185 1.74767932489451 0.0550944509710267 0.262719776810376 GO:0017069 snRNA binding 10/1975 54/18639 0.185185185185185 1.74767932489451 0.0550944509710267 0.262719776810376 GO:0051536 iron-sulfur cluster binding 13/1975 76/18639 0.171052631578947 1.61430379746835 0.0552746554730968 0.262719776810376 GO:0015631 tubulin binding 51/1975 385/18639 0.132467532467532 1.25015814565182 0.0555197897341945 0.262837734733706 GO:0017124 SH3 domain binding 18/1975 115/18639 0.156521739130435 1.47716895982389 0.0588378924737058 0.276352778429649 GO:0101005 deubiquitinase activity 18/1975 115/18639 0.156521739130435 1.47716895982389 0.0588378924737058 0.276352778429649 GO:0008266 poly(U) RNA binding 6/1975 27/18639 0.222222222222222 2.09721518987342 0.0594363404931397 0.27806884003261 GO:0008234 cysteine-type peptidase activity 27/1975 187/18639 0.144385026737968 1.36262912069316 0.0597719496963594 0.278546624952175 GO:0031072 heat shock protein binding 20/1975 131/18639 0.152671755725191 1.44083486327181 0.060069764664303 0.278845249978652 GO:0051540 metal cluster binding 13/1975 77/18639 0.168831168831169 1.59333881308565 0.0603311531690208 0.278973122986984 GO:0141050 histone H3K deacetylase activity 4/1975 15/18639 0.266666666666667 2.5166582278481 0.0662322829212606 0.303904282788707 GO:0141051 histone H4K deacetylase activity 4/1975 15/18639 0.266666666666667 2.5166582278481 0.0662322829212606 0.303904282788707 GO:0019887 protein kinase regulator activity 35/1975 255/18639 0.137254901960784 1.29533879374535 0.0665186757852109 0.304048966328569 GO:1990782 protein tyrosine kinase binding 18/1975 117/18639 0.153846153846154 1.4519182083739 0.0674566703615522 0.307159571531801 GO:0046875 ephrin receptor binding 6/1975 28/18639 0.214285714285714 2.02231464737794 0.0691467074624216 0.311365605079181 GO:0051537 2 iron, 2 sulfur cluster binding 6/1975 28/18639 0.214285714285714 2.02231464737794 0.0691467074624216 0.311365605079181 GO:0016410 N-acyltransferase activity 15/1975 94/18639 0.159574468085106 1.50597899272825 0.0694243511744025 0.311365605079181 GO:0042562 hormone binding 15/1975 94/18639 0.159574468085106 1.50597899272825 0.0694243511744025 0.311365605079181 GO:0016859 cis-trans isomerase activity 8/1975 42/18639 0.19047619047619 1.7976130198915 0.0708733003499215 0.315875999053945 GO:0140566 histone reader activity 7/1975 35/18639 0.2 1.88749367088608 0.0709595706173153 0.315875999053945 GO:0070034 telomerase RNA binding 5/1975 22/18639 0.227272727272727 2.14487917146145 0.0759290796562394 0.334947548332772 GO:0004712 protein serine/threonine/tyrosine kinase activity 8/1975 43/18639 0.186046511627907 1.75580806594054 0.079365641915821 0.334947548332772 GO:0008017 microtubule binding 37/1975 276/18639 0.134057971014493 1.26516785910842 0.0797189387364663 0.334947548332772 GO:0005525 GTP binding 49/1975 378/18639 0.12962962962963 1.22337552742616 0.0797410296423015 0.334947548332772 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 7/1975 36/18639 0.194444444444444 1.83506329113924 0.0804043990545822 0.334947548332772 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 7/1975 36/18639 0.194444444444444 1.83506329113924 0.0804043990545822 0.334947548332772 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 7/1975 36/18639 0.194444444444444 1.83506329113924 0.0804043990545822 0.334947548332772 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0005381 iron ion transmembrane transporter activity 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0031996 thioesterase binding 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0043121 neurotrophin binding 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0050815 phosphoserine residue binding 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0097177 mitochondrial ribosome binding 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0099122 RNA polymerase II C-terminal domain binding 3/1975 10/18639 0.3 2.83124050632911 0.0807725049813844 0.334947548332772 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/1975 16/18639 0.25 2.35936708860759 0.0811817367491564 0.334947548332772 GO:0005024 transforming growth factor beta receptor activity 4/1975 16/18639 0.25 2.35936708860759 0.0811817367491564 0.334947548332772 GO:0043023 ribosomal large subunit binding 4/1975 16/18639 0.25 2.35936708860759 0.0811817367491564 0.334947548332772 GO:0070411 I-SMAD binding 4/1975 16/18639 0.25 2.35936708860759 0.0811817367491564 0.334947548332772 GO:0004521 RNA endonuclease activity 12/1975 73/18639 0.164383561643836 1.55136466100225 0.081477967254336 0.334947548332772 GO:0008408 3'-5' exonuclease activity 10/1975 58/18639 0.172413793103448 1.6271497162811 0.0821584432611208 0.334947548332772 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 10/1975 58/18639 0.172413793103448 1.6271497162811 0.0821584432611208 0.334947548332772 GO:0015078 proton transmembrane transporter activity 26/1975 185/18639 0.140540540540541 1.32634690386589 0.0822628932619466 0.334947548332772 GO:0030971 receptor tyrosine kinase binding 13/1975 81/18639 0.160493827160494 1.51465541490858 0.0836006010664179 0.339236452626655 GO:0051082 unfolded protein binding 18/1975 121/18639 0.148760330578512 1.40392091222931 0.087166301936595 0.352506434611382 GO:0141108 transporter regulator activity 24/1975 170/18639 0.141176470588235 1.33234847356664 0.0884979482140339 0.35668260884913 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 19/1975 130/18639 0.146153846153846 1.37932229795521 0.0922679659515705 0.370625196566409 GO:0019001 guanyl nucleotide binding 51/1975 400/18639 0.1275 1.20327721518987 0.0936230878282544 0.373552989227784 GO:0032561 guanyl ribonucleotide binding 51/1975 400/18639 0.1275 1.20327721518987 0.0936230878282544 0.373552989227784 GO:0005080 protein kinase C binding 9/1975 52/18639 0.173076923076923 1.63340798442064 0.0941851794566733 0.374543063639371 GO:0030295 protein kinase activator activity 20/1975 139/18639 0.143884892086331 1.35790911574538 0.0970150759106668 0.381146200707013 GO:0008135 translation factor activity, RNA binding 13/1975 83/18639 0.156626506024096 1.47815769406741 0.0971019135482823 0.381146200707013 GO:0032977 membrane insertase activity 4/1975 17/18639 0.235294117647059 2.22058078927774 0.0976337373037805 0.381146200707013 GO:0038191 neuropilin binding 4/1975 17/18639 0.235294117647059 2.22058078927774 0.0976337373037805 0.381146200707013 GO:0048038 quinone binding 4/1975 17/18639 0.235294117647059 2.22058078927774 0.0976337373037805 0.381146200707013 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/1975 45/18639 0.177777777777778 1.67777215189873 0.0980820482959372 0.381146200707013 GO:0046915 transition metal ion transmembrane transporter activity 8/1975 45/18639 0.177777777777778 1.67777215189873 0.0980820482959372 0.381146200707013 GO:0032934 sterol binding 11/1975 68/18639 0.161764705882353 1.52664929262844 0.101148378166474 0.383139360251553 GO:0042162 telomeric DNA binding 7/1975 38/18639 0.184210526315789 1.73848101265823 0.101355834297012 0.383139360251553 GO:0019209 kinase activator activity 21/1975 148/18639 0.141891891891892 1.33910023947999 0.10143639400922 0.383139360251553 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0002162 dystroglycan binding 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0005114 type II transforming growth factor beta receptor binding 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0005225 volume-sensitive anion channel activity 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0048185 activin binding 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0070697 activin receptor binding 3/1975 11/18639 0.272727272727273 2.57385500575374 0.102619470738211 0.383139360251553 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1975 24/18639 0.208333333333333 1.96613924050633 0.103008144633253 0.383139360251553 GO:0070300 phosphatidic acid binding 5/1975 24/18639 0.208333333333333 1.96613924050633 0.103008144633253 0.383139360251553 GO:0098631 cell adhesion mediator activity 12/1975 76/18639 0.157894736842105 1.49012658227848 0.103091143873217 0.383139360251553 GO:0004860 protein kinase inhibitor activity 13/1975 84/18639 0.154761904761905 1.46056057866184 0.104323088176444 0.385317164688849 GO:0180051 translation factor activity 13/1975 84/18639 0.154761904761905 1.46056057866184 0.104323088176444 0.385317164688849 GO:0042277 peptide binding 33/1975 249/18639 0.132530120481928 1.25074881805704 0.104862130998413 0.385962308852793 GO:0005496 steroid binding 16/1975 108/18639 0.148148148148148 1.39814345991561 0.105144803333745 0.385962308852793 GO:0051219 phosphoprotein binding 14/1975 93/18639 0.150537634408602 1.42069416088199 0.112203294625517 0.410608989227735 GO:0140463 chromatin-protein adaptor activity 9/1975 54/18639 0.166666666666667 1.57291139240506 0.112999385923002 0.412257698489728 GO:0000900 mRNA regulatory element binding translation repressor activity 4/1975 18/18639 0.222222222222222 2.09721518987342 0.115496704458589 0.415022796443062 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 4/1975 18/18639 0.222222222222222 2.09721518987342 0.115496704458589 0.415022796443062 GO:0017075 syntaxin-1 binding 4/1975 18/18639 0.222222222222222 2.09721518987342 0.115496704458589 0.415022796443062 GO:0017128 phospholipid scramblase activity 4/1975 18/18639 0.222222222222222 2.09721518987342 0.115496704458589 0.415022796443062 GO:1990381 ubiquitin-specific protease binding 4/1975 18/18639 0.222222222222222 2.09721518987342 0.115496704458589 0.415022796443062 GO:0030515 snoRNA binding 6/1975 32/18639 0.1875 1.7695253164557 0.116460553260393 0.415980359400147 GO:0140142 nucleocytoplasmic carrier activity 6/1975 32/18639 0.1875 1.7695253164557 0.116460553260393 0.415980359400147 GO:0000030 mannosyltransferase activity 5/1975 25/18639 0.2 1.88749367088608 0.118111174675214 0.419364974367649 GO:0017056 structural constituent of nuclear pore 5/1975 25/18639 0.2 1.88749367088608 0.118111174675214 0.419364974367649 GO:0001784 phosphotyrosine residue binding 8/1975 47/18639 0.170212765957447 1.60637759224347 0.119069249444524 0.420265131915139 GO:0043495 protein-membrane adaptor activity 8/1975 47/18639 0.170212765957447 1.60637759224347 0.119069249444524 0.420265131915139 GO:0016247 channel regulator activity 23/1975 168/18639 0.136904761904762 1.29203435804702 0.120358012188051 0.423560792154411 GO:0019207 kinase regulator activity 37/1975 287/18639 0.128919860627178 1.21667710492656 0.121160321925182 0.425130188402182 GO:0099106 ion channel regulator activity 22/1975 160/18639 0.1375 1.29765189873418 0.122336187138013 0.42799727640953 GO:0004532 RNA exonuclease activity 7/1975 40/18639 0.175 1.65155696202532 0.124979470914976 0.428716083546951 GO:0000340 RNA 7-methylguanosine cap binding 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0005025 transforming growth factor beta receptor activity, type I 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0005026 transforming growth factor beta receptor activity, type II 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0016361 activin receptor activity, type I 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0016362 activin receptor activity, type II 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0017002 activin receptor activity 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0035251 UDP-glucosyltransferase activity 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0042301 phosphate ion binding 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0070008 serine-type exopeptidase activity 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1975 12/18639 0.25 2.35936708860759 0.12649460302475 0.428716083546951 GO:0005160 transforming growth factor beta receptor binding 5/1975 26/18639 0.192307692307692 1.81489776046738 0.134188092715551 0.445023199680195 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 5/1975 26/18639 0.192307692307692 1.81489776046738 0.134188092715551 0.445023199680195 GO:0008143 poly(A) binding 5/1975 26/18639 0.192307692307692 1.81489776046738 0.134188092715551 0.445023199680195 GO:0052742 phosphatidylinositol kinase activity 5/1975 26/18639 0.192307692307692 1.81489776046738 0.134188092715551 0.445023199680195 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/1975 19/18639 0.210526315789474 1.98683544303797 0.134663348771626 0.445023199680195 GO:0005520 insulin-like growth factor binding 4/1975 19/18639 0.210526315789474 1.98683544303797 0.134663348771626 0.445023199680195 GO:0042800 histone H3K4 methyltransferase activity 4/1975 19/18639 0.210526315789474 1.98683544303797 0.134663348771626 0.445023199680195 GO:0050145 nucleoside monophosphate kinase activity 4/1975 19/18639 0.210526315789474 1.98683544303797 0.134663348771626 0.445023199680195 GO:1990380 K48-linked deubiquitinase activity 4/1975 19/18639 0.210526315789474 1.98683544303797 0.134663348771626 0.445023199680195 GO:0016651 oxidoreductase activity, acting on NAD(P)H 13/1975 88/18639 0.147727272727273 1.39417146144994 0.136311315560889 0.449224860398178 GO:0140098 catalytic activity, acting on RNA 48/1975 387/18639 0.124031007751938 1.17053871062702 0.139854018347885 0.459630423936712 GO:0016763 pentosyltransferase activity 8/1975 49/18639 0.163265306122449 1.540811159907 0.142237788654064 0.46618044468214 GO:0043539 protein serine/threonine kinase activator activity 11/1975 73/18639 0.150684931506849 1.4220842725854 0.146314769863998 0.478228823144519 GO:0000149 SNARE binding 15/1975 106/18639 0.141509433962264 1.33549080487222 0.150511473133634 0.486512537978036 GO:0035198 miRNA binding 7/1975 42/18639 0.166666666666667 1.57291139240506 0.151123339019146 0.486512537978036 GO:0001671 ATPase activator activity 5/1975 27/18639 0.185185185185185 1.74767932489451 0.151177127311554 0.486512537978036 GO:0004535 poly(A)-specific ribonuclease activity 3/1975 13/18639 0.230769230769231 2.17787731256086 0.15211163173999 0.486512537978036 GO:0031994 insulin-like growth factor I binding 3/1975 13/18639 0.230769230769231 2.17787731256086 0.15211163173999 0.486512537978036 GO:0046975 histone H3K36 methyltransferase activity 3/1975 13/18639 0.230769230769231 2.17787731256086 0.15211163173999 0.486512537978036 GO:0061459 L-arginine transmembrane transporter activity 3/1975 13/18639 0.230769230769231 2.17787731256086 0.15211163173999 0.486512537978036 GO:0070123 transforming growth factor beta receptor activity, type III 3/1975 13/18639 0.230769230769231 2.17787731256086 0.15211163173999 0.486512537978036 GO:0019210 kinase inhibitor activity 13/1975 90/18639 0.144444444444444 1.36318987341772 0.15411871702523 0.487947898689302 GO:0015605 organophosphate ester transmembrane transporter activity 8/1975 50/18639 0.16 1.50999493670886 0.154599445482833 0.487947898689302 GO:0032813 tumor necrosis factor receptor superfamily binding 8/1975 50/18639 0.16 1.50999493670886 0.154599445482833 0.487947898689302 GO:0048020 CCR chemokine receptor binding 8/1975 50/18639 0.16 1.50999493670886 0.154599445482833 0.487947898689302 GO:0000339 RNA cap binding 4/1975 20/18639 0.2 1.88749367088608 0.155014462366509 0.487947898689302 GO:0016004 phospholipase activator activity 4/1975 20/18639 0.2 1.88749367088608 0.155014462366509 0.487947898689302 GO:0061980 regulatory RNA binding 9/1975 58/18639 0.155172413793103 1.46443474465299 0.156294389963116 0.488661572536177 GO:0035401 histone H3Y41 kinase activity 16/1975 115/18639 0.139130434782609 1.31303907539901 0.156470008976379 0.488661572536177 GO:0140801 histone H2AXY142 kinase activity 16/1975 115/18639 0.139130434782609 1.31303907539901 0.156470008976379 0.488661572536177 GO:0000175 3'-5'-RNA exonuclease activity 6/1975 35/18639 0.171428571428571 1.61785171790235 0.160198569219099 0.497700242391627 GO:0043015 gamma-tubulin binding 6/1975 35/18639 0.171428571428571 1.61785171790235 0.160198569219099 0.497700242391627 GO:0004518 nuclease activity 27/1975 209/18639 0.129186602870813 1.21919447640967 0.162026006713378 0.502070197426128 GO:0019789 SUMO transferase activity 5/1975 28/18639 0.178571428571429 1.68526220614828 0.169009827278757 0.521004454634514 GO:0046966 nuclear thyroid hormone receptor binding 5/1975 28/18639 0.178571428571429 1.68526220614828 0.169009827278757 0.521004454634514 GO:0005201 extracellular matrix structural constituent 22/1975 168/18639 0.130952380952381 1.23585895117541 0.174443463399424 0.535551987944043 GO:0044390 ubiquitin-like protein conjugating enzyme binding 6/1975 36/18639 0.166666666666667 1.57291139240506 0.176157403252002 0.535551987944043 GO:0055106 ubiquitin-protein transferase regulator activity 6/1975 36/18639 0.166666666666667 1.57291139240506 0.176157403252002 0.535551987944043 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/1975 21/18639 0.19047619047619 1.7976130198915 0.176422406757761 0.535551987944043 GO:0035613 RNA stem-loop binding 4/1975 21/18639 0.19047619047619 1.7976130198915 0.176422406757761 0.535551987944043 GO:0072542 protein phosphatase activator activity 4/1975 21/18639 0.19047619047619 1.7976130198915 0.176422406757761 0.535551987944043 GO:0017022 myosin binding 11/1975 76/18639 0.144736842105263 1.36594936708861 0.1777037436641 0.537092845721026 GO:0019992 diacylglycerol binding 3/1975 14/18639 0.214285714285714 2.02231464737794 0.179181016426629 0.537092845721026 GO:0034236 protein kinase A catalytic subunit binding 3/1975 14/18639 0.214285714285714 2.02231464737794 0.179181016426629 0.537092845721026 GO:0098821 BMP receptor activity 3/1975 14/18639 0.214285714285714 2.02231464737794 0.179181016426629 0.537092845721026 GO:1990825 sequence-specific mRNA binding 3/1975 14/18639 0.214285714285714 2.02231464737794 0.179181016426629 0.537092845721026 GO:0005178 integrin binding 21/1975 161/18639 0.130434782608696 1.23097413318657 0.185963091696105 0.556024983442238 GO:0004857 enzyme inhibitor activity 50/1975 416/18639 0.120192307692308 1.13431110029211 0.189878486255216 0.566312585256182 GO:0019213 deacetylase activity 6/1975 37/18639 0.162162162162162 1.53040027369141 0.192728668779621 0.573379805122415 GO:0008083 growth factor activity 21/1975 162/18639 0.12962962962963 1.22337552742616 0.193647242050507 0.574679501906106 GO:0140303 intramembrane lipid transporter activity 7/1975 45/18639 0.155555555555556 1.46805063291139 0.194587647006313 0.576037376869803 GO:0004407 histone deacetylase activity 4/1975 22/18639 0.181818181818182 1.71590333716916 0.198754257224766 0.579740412882996 GO:0008093 cytoskeletal anchor activity 4/1975 22/18639 0.181818181818182 1.71590333716916 0.198754257224766 0.579740412882996 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 4/1975 22/18639 0.181818181818182 1.71590333716916 0.198754257224766 0.579740412882996 GO:0033558 protein lysine deacetylase activity 4/1975 22/18639 0.181818181818182 1.71590333716916 0.198754257224766 0.579740412882996 GO:0061133 endopeptidase activator activity 4/1975 22/18639 0.181818181818182 1.71590333716916 0.198754257224766 0.579740412882996 GO:0140784 metal ion sensor activity 4/1975 22/18639 0.181818181818182 1.71590333716916 0.198754257224766 0.579740412882996 GO:0019199 transmembrane receptor protein kinase activity 11/1975 78/18639 0.141025641025641 1.33092502434275 0.200250731474004 0.582680786947529 GO:0008276 protein methyltransferase activity 13/1975 95/18639 0.136842105263158 1.29144303797468 0.203534682284301 0.586374199916929 GO:0035591 signaling adaptor activity 17/1975 129/18639 0.131782945736434 1.24369738004121 0.204396642441438 0.586374199916929 GO:0001968 fibronectin binding 5/1975 30/18639 0.166666666666667 1.57291139240506 0.206907148115131 0.586374199916929 GO:0031210 phosphatidylcholine binding 5/1975 30/18639 0.166666666666667 1.57291139240506 0.206907148115131 0.586374199916929 GO:0000774 adenyl-nucleotide exchange factor activity 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0004865 protein serine/threonine phosphatase inhibitor activity 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0005041 low-density lipoprotein particle receptor activity 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0005523 tropomyosin binding 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0031005 filamin binding 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0061578 K63-linked deubiquitinase activity 3/1975 15/18639 0.2 1.88749367088608 0.207418199802971 0.586374199916929 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6/1975 38/18639 0.157894736842105 1.49012658227848 0.209861075245111 0.591877689757487 GO:0004197 cysteine-type endopeptidase activity 12/1975 88/18639 0.136363636363636 1.28692750287687 0.219064291629636 0.616376650740934 GO:0000295 adenine nucleotide transmembrane transporter activity 4/1975 23/18639 0.173913043478261 1.64129884424876 0.221874584778311 0.621353003850998 GO:0008171 O-methyltransferase activity 4/1975 23/18639 0.173913043478261 1.64129884424876 0.221874584778311 0.621353003850998 GO:0098632 cell-cell adhesion mediator activity 8/1975 55/18639 0.145454545454545 1.37272266973533 0.223287273367945 0.623844770791471 GO:0005504 fatty acid binding 7/1975 47/18639 0.148936170212766 1.40558039321304 0.226001999226778 0.629718486949694 GO:0005164 tumor necrosis factor receptor binding 5/1975 31/18639 0.161290322580645 1.52217231523071 0.226813452221421 0.629718486949694 GO:0000217 DNA secondary structure binding 6/1975 39/18639 0.153846153846154 1.4519182083739 0.227500978939915 0.629718486949694 GO:0016776 phosphotransferase activity, phosphate group as acceptor 6/1975 39/18639 0.153846153846154 1.4519182083739 0.227500978939915 0.629718486949694 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 12/1975 89/18639 0.134831460674157 1.27246764329398 0.230596190987699 0.635337773321768 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 12/1975 89/18639 0.134831460674157 1.27246764329398 0.230596190987699 0.635337773321768 GO:0004725 protein tyrosine phosphatase activity 13/1975 98/18639 0.13265306122449 1.25190906742444 0.23618891893224 0.642833215702448 GO:0004707 MAP kinase activity 3/1975 16/18639 0.1875 1.7695253164557 0.236549691276928 0.642833215702448 GO:0005521 lamin binding 3/1975 16/18639 0.1875 1.7695253164557 0.236549691276928 0.642833215702448 GO:0008296 3'-5'-DNA exonuclease activity 3/1975 16/18639 0.1875 1.7695253164557 0.236549691276928 0.642833215702448 GO:0015562 efflux transmembrane transporter activity 3/1975 16/18639 0.1875 1.7695253164557 0.236549691276928 0.642833215702448 GO:0097027 ubiquitin-protein transferase activator activity 3/1975 16/18639 0.1875 1.7695253164557 0.236549691276928 0.642833215702448 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 28/1975 229/18639 0.122270742358079 1.15392626167708 0.237886419843315 0.644996588347897 GO:0140793 histone H2AXY142 phosphatase activity 12/1975 90/18639 0.133333333333333 1.25832911392405 0.242361956212695 0.655641301047042 GO:0005085 guanyl-nucleotide exchange factor activity 28/1975 230/18639 0.121739130434783 1.14890919097413 0.245216967182741 0.658557106200306 GO:0015036 disulfide oxidoreductase activity 6/1975 40/18639 0.15 1.41562025316456 0.245593009767845 0.658557106200306 GO:0050997 quaternary ammonium group binding 6/1975 40/18639 0.15 1.41562025316456 0.245593009767845 0.658557106200306 GO:0060229 lipase activator activity 4/1975 24/18639 0.166666666666667 1.57291139240506 0.245647872807323 0.658557106200306 GO:0035091 phosphatidylinositol binding 34/1975 284/18639 0.119718309859155 1.12983776074166 0.249567196303362 0.667564271726257 GO:0015932 nucleobase-containing compound transmembrane transporter activity 8/1975 57/18639 0.140350877192982 1.32455696202532 0.25346598674171 0.67496634415817 GO:0016504 peptidase activator activity 8/1975 57/18639 0.140350877192982 1.32455696202532 0.25346598674171 0.67496634415817 GO:0001540 amyloid-beta binding 11/1975 83/18639 0.132530120481928 1.25074881805704 0.261480657717305 0.693214277014988 GO:0030165 PDZ domain binding 11/1975 83/18639 0.132530120481928 1.25074881805704 0.261480657717305 0.693214277014988 GO:0042169 SH2 domain binding 6/1975 41/18639 0.146341463414634 1.38109292991664 0.264080668715314 0.698278358395156 GO:0004549 tRNA-specific ribonuclease activity 3/1975 17/18639 0.176470588235294 1.6654355919583 0.266317395699745 0.698278358395156 GO:0008484 sulfuric ester hydrolase activity 3/1975 17/18639 0.176470588235294 1.6654355919583 0.266317395699745 0.698278358395156 GO:0017110 nucleoside diphosphate phosphatase activity 3/1975 17/18639 0.176470588235294 1.6654355919583 0.266317395699745 0.698278358395156 GO:0070403 NAD+ binding 3/1975 17/18639 0.176470588235294 1.6654355919583 0.266317395699745 0.698278358395156 GO:0015662 P-type ion transporter activity 4/1975 25/18639 0.16 1.50999493670886 0.269940577213439 0.704680762835082 GO:0140358 P-type transmembrane transporter activity 4/1975 25/18639 0.16 1.50999493670886 0.269940577213439 0.704680762835082 GO:0004527 exonuclease activity 11/1975 84/18639 0.130952380952381 1.23585895117541 0.274431210056565 0.714839374666992 GO:0140034 methylation-dependent protein binding 10/1975 76/18639 0.131578947368421 1.24177215189873 0.282749930596149 0.716426012627327 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0004382 GDP phosphatase activity 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0005345 purine nucleobase transmembrane transporter activity 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0008140 cAMP response element binding protein binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0016868 intramolecular phosphotransferase activity 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0033204 ribonuclease P RNA binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0035374 chondroitin sulfate binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0043295 glutathione binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0051880 G-quadruplex DNA binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0070513 death domain binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:1905394 retromer complex binding 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/1975 10/18639 0.2 1.88749367088608 0.28705082484146 0.716426012627327 GO:0015035 protein-disulfide reductase activity 5/1975 34/18639 0.147058823529412 1.38786299329859 0.289378329196532 0.716690651977391 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 5/1975 34/18639 0.147058823529412 1.38786299329859 0.289378329196532 0.716690651977391 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 5/1975 34/18639 0.147058823529412 1.38786299329859 0.289378329196532 0.716690651977391 GO:0030145 manganese ion binding 9/1975 68/18639 0.132352941176471 1.24907669396873 0.291541729020524 0.716690651977391 GO:0005112 Notch binding 4/1975 26/18639 0.153846153846154 1.4519182083739 0.294622847122146 0.716690651977391 GO:0008157 protein phosphatase 1 binding 4/1975 26/18639 0.153846153846154 1.4519182083739 0.294622847122146 0.716690651977391 GO:0015216 purine nucleotide transmembrane transporter activity 4/1975 26/18639 0.153846153846154 1.4519182083739 0.294622847122146 0.716690651977391 GO:0043548 phosphatidylinositol 3-kinase binding 4/1975 26/18639 0.153846153846154 1.4519182083739 0.294622847122146 0.716690651977391 GO:0000400 four-way junction DNA binding 3/1975 18/18639 0.166666666666667 1.57291139240506 0.296481533947976 0.716690651977391 GO:0008308 voltage-gated monoatomic anion channel activity 3/1975 18/18639 0.166666666666667 1.57291139240506 0.296481533947976 0.716690651977391 GO:0030228 lipoprotein particle receptor activity 3/1975 18/18639 0.166666666666667 1.57291139240506 0.296481533947976 0.716690651977391 GO:0031690 adrenergic receptor binding 3/1975 18/18639 0.166666666666667 1.57291139240506 0.296481533947976 0.716690651977391 GO:0050811 GABA receptor binding 3/1975 18/18639 0.166666666666667 1.57291139240506 0.296481533947976 0.716690651977391 GO:0098641 cadherin binding involved in cell-cell adhesion 3/1975 18/18639 0.166666666666667 1.57291139240506 0.296481533947976 0.716690651977391 GO:1901611 phosphatidylglycerol binding 3/1975 18/18639 0.166666666666667 1.57291139240506 0.296481533947976 0.716690651977391 GO:0003724 RNA helicase activity 10/1975 77/18639 0.12987012987013 1.22564524083511 0.296768803082004 0.716690651977391 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 8/1975 60/18639 0.133333333333333 1.25832911392405 0.300861944688334 0.723645766155609 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 8/1975 60/18639 0.133333333333333 1.25832911392405 0.300861944688334 0.723645766155609 GO:0008375 acetylglucosaminyltransferase activity 6/1975 43/18639 0.13953488372093 1.3168560494554 0.302014565860692 0.724956493102225 GO:0019905 syntaxin binding 8/1975 61/18639 0.131147540983607 1.23770076779415 0.317096793709935 0.747815461401639 GO:0005385 zinc ion transmembrane transporter activity 4/1975 27/18639 0.148148148148148 1.39814345991561 0.319569928828336 0.747815461401639 GO:0016248 channel inhibitor activity 6/1975 44/18639 0.136363636363636 1.28692750287687 0.321347023893744 0.747815461401639 GO:0019205 nucleobase-containing compound kinase activity 6/1975 44/18639 0.136363636363636 1.28692750287687 0.321347023893744 0.747815461401639 GO:0043014 alpha-tubulin binding 6/1975 44/18639 0.136363636363636 1.28692750287687 0.321347023893744 0.747815461401639 GO:0008186 ATP-dependent activity, acting on RNA 10/1975 79/18639 0.126582278481013 1.19461624739625 0.32530918102095 0.747815461401639 GO:0042577 lipid phosphatase activity 3/1975 19/18639 0.157894736842105 1.49012658227848 0.326822443668543 0.747815461401639 GO:0046527 glucosyltransferase activity 3/1975 19/18639 0.157894736842105 1.49012658227848 0.326822443668543 0.747815461401639 GO:0003953 NAD+ nucleosidase activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0008526 phosphatidylinositol transfer activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0015173 aromatic amino acid transmembrane transporter activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0015205 nucleobase transmembrane transporter activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0032794 GTPase activating protein binding 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0097493 structural molecule activity conferring elasticity 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0140031 phosphorylation-dependent protein binding 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:1900750 oligopeptide binding 2/1975 11/18639 0.181818181818182 1.71590333716916 0.328035570197738 0.747815461401639 GO:0004864 protein phosphatase inhibitor activity 7/1975 53/18639 0.132075471698113 1.24645808454741 0.32846211380927 0.747815461401639 GO:0005246 calcium channel regulator activity 7/1975 53/18639 0.132075471698113 1.24645808454741 0.32846211380927 0.747815461401639 GO:0004190 aspartic-type endopeptidase activity 5/1975 36/18639 0.138888888888889 1.31075949367089 0.332642303054185 0.754452980120994 GO:0005484 SNAP receptor activity 5/1975 36/18639 0.138888888888889 1.31075949367089 0.332642303054185 0.754452980120994 GO:0015179 L-amino acid transmembrane transporter activity 8/1975 62/18639 0.129032258064516 1.21773785218457 0.333494426217287 0.754950380412189 GO:0051539 4 iron, 4 sulfur cluster binding 6/1975 45/18639 0.133333333333333 1.25832911392405 0.340848466491811 0.768680946171513 GO:0141110 transporter inhibitor activity 6/1975 45/18639 0.133333333333333 1.25832911392405 0.340848466491811 0.768680946171513 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/1975 54/18639 0.12962962962963 1.22337552742616 0.34629619968419 0.778025171795177 GO:0051287 NAD binding 7/1975 54/18639 0.12962962962963 1.22337552742616 0.34629619968419 0.778025171795177 GO:0042379 chemokine receptor binding 9/1975 72/18639 0.125 1.1796835443038 0.352598581796877 0.790695691886606 GO:0043394 proteoglycan binding 5/1975 37/18639 0.135135135135135 1.27533356140951 0.354503808409586 0.791951316982472 GO:0070001 aspartic-type peptidase activity 5/1975 37/18639 0.135135135135135 1.27533356140951 0.354503808409586 0.791951316982472 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1975 20/18639 0.15 1.41562025316456 0.357141499192431 0.791951316982472 GO:0015095 magnesium ion transmembrane transporter activity 3/1975 20/18639 0.15 1.41562025316456 0.357141499192431 0.791951316982472 GO:0030742 GTP-dependent protein binding 3/1975 20/18639 0.15 1.41562025316456 0.357141499192431 0.791951316982472 GO:0031418 L-ascorbic acid binding 3/1975 20/18639 0.15 1.41562025316456 0.357141499192431 0.791951316982472 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1975 46/18639 0.130434782608696 1.23097413318657 0.360464359714999 0.797836699703142 GO:0002020 protease binding 16/1975 136/18639 0.117647058823529 1.11029039463887 0.367958146894408 0.798971109115231 GO:0004000 adenosine deaminase activity 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0004526 ribonuclease P activity 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0005078 MAP-kinase scaffold activity 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0005095 GTPase inhibitor activity 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0031543 peptidyl-proline dioxygenase activity 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0045295 gamma-catenin binding 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0070410 co-SMAD binding 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1975 12/18639 0.166666666666667 1.57291139240506 0.368343763632336 0.798971109115231 GO:0003785 actin monomer binding 4/1975 29/18639 0.137931034482759 1.30171977302488 0.369791415677497 0.799204998013141 GO:0106222 lncRNA binding 4/1975 29/18639 0.137931034482759 1.30171977302488 0.369791415677497 0.799204998013141 GO:0000146 microfilament motor activity 5/1975 38/18639 0.131578947368421 1.24177215189873 0.376419374040568 0.810592623159562 GO:0043531 ADP binding 5/1975 38/18639 0.131578947368421 1.24177215189873 0.376419374040568 0.810592623159562 GO:0140938 histone H3 methyltransferase activity 6/1975 47/18639 0.127659574468085 1.2047831941826 0.380141778323031 0.817133588359236 GO:0019212 phosphatase inhibitor activity 7/1975 56/18639 0.125 1.1796835443038 0.382238102797897 0.817704049703239 GO:0019843 rRNA binding 8/1975 65/18639 0.123076923076923 1.16153456669912 0.383335726030214 0.817704049703239 GO:0160215 deacylase activity 8/1975 65/18639 0.123076923076923 1.16153456669912 0.383335726030214 0.817704049703239 GO:0035064 methylated histone binding 9/1975 74/18639 0.121621621621622 1.14780020526856 0.383779761470577 0.817704049703239 GO:0005126 cytokine receptor binding 31/1975 275/18639 0.112727272727273 1.06386006904488 0.385204281919125 0.817704049703239 GO:0005123 death receptor binding 3/1975 21/18639 0.142857142857143 1.34820976491863 0.387261347931542 0.817704049703239 GO:0009975 cyclase activity 3/1975 21/18639 0.142857142857143 1.34820976491863 0.387261347931542 0.817704049703239 GO:0015174 basic amino acid transmembrane transporter activity 3/1975 21/18639 0.142857142857143 1.34820976491863 0.387261347931542 0.817704049703239 GO:0036122 BMP binding 3/1975 21/18639 0.142857142857143 1.34820976491863 0.387261347931542 0.817704049703239 GO:0061891 calcium ion sensor activity 3/1975 21/18639 0.142857142857143 1.34820976491863 0.387261347931542 0.817704049703239 GO:0031624 ubiquitin conjugating enzyme binding 4/1975 30/18639 0.133333333333333 1.25832911392405 0.394850533764015 0.832255630354186 GO:0008238 exopeptidase activity 12/1975 102/18639 0.117647058823529 1.11029039463887 0.396275097986182 0.833785170895089 GO:0051213 dioxygenase activity 11/1975 93/18639 0.118279569892473 1.11625969783585 0.397478124713579 0.834844018984682 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/1975 39/18639 0.128205128205128 1.20993184031159 0.398319138025957 0.835140125948976 GO:0044183 protein folding chaperone 9/1975 75/18639 0.12 1.13249620253165 0.399441356594579 0.83563028379292 GO:0008235 metalloexopeptidase activity 8/1975 66/18639 0.121212121212121 1.14393555811277 0.400058670404152 0.83563028379292 GO:0140767 enzyme-substrate adaptor activity 16/1975 139/18639 0.115107913669065 1.0863272925963 0.402264825205756 0.83563028379292 GO:1901981 phosphatidylinositol phosphate binding 21/1975 185/18639 0.113513513513514 1.07128019158399 0.403306431473432 0.83563028379292 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0005035 death receptor activity 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0008253 5'-nucleotidase activity 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0030955 potassium ion binding 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0043560 insulin receptor substrate binding 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0097157 pre-mRNA intronic binding 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0140666 annealing activity 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0140852 histone ubiquitin ligase activity 2/1975 13/18639 0.153846153846154 1.4519182083739 0.407658696703671 0.83563028379292 GO:0042054 histone methyltransferase activity 8/1975 67/18639 0.119402985074627 1.12686189306631 0.416784499078415 0.848094124405777 GO:0034062 5'-3' RNA polymerase activity 3/1975 22/18639 0.136363636363636 1.28692750287687 0.417025625411559 0.848094124405777 GO:0097747 RNA polymerase activity 3/1975 22/18639 0.136363636363636 1.28692750287687 0.417025625411559 0.848094124405777 GO:0140517 protein-RNA adaptor activity 3/1975 22/18639 0.136363636363636 1.28692750287687 0.417025625411559 0.848094124405777 GO:0008327 methyl-CpG binding 4/1975 31/18639 0.129032258064516 1.21773785218457 0.41974491621477 0.848094124405777 GO:0061791 GTPase motor activity 5/1975 40/18639 0.125 1.1796835443038 0.420137156348545 0.848094124405777 GO:0071949 FAD binding 5/1975 40/18639 0.125 1.1796835443038 0.420137156348545 0.848094124405777 GO:0140662 ATP-dependent protein folding chaperone 5/1975 40/18639 0.125 1.1796835443038 0.420137156348545 0.848094124405777 GO:1990606 membrane scission GTPase motor activity 5/1975 40/18639 0.125 1.1796835443038 0.420137156348545 0.848094124405777 GO:0070888 E-box binding 7/1975 59/18639 0.11864406779661 1.1196996352714 0.43624680900518 0.871413829520966 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1975 41/18639 0.121951219512195 1.15091077493053 0.441811668519827 0.871413829520966 GO:0042287 MHC protein binding 5/1975 41/18639 0.121951219512195 1.15091077493053 0.441811668519827 0.871413829520966 GO:0031369 translation initiation factor binding 4/1975 32/18639 0.125 1.1796835443038 0.444387165066702 0.871413829520966 GO:0120015 sterol transfer activity 4/1975 32/18639 0.125 1.1796835443038 0.444387165066702 0.871413829520966 GO:0004705 JUN kinase activity 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0005545 1-phosphatidylinositol binding 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0008174 mRNA methyltransferase activity 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0008195 phosphatidate phosphatase activity 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0032036 myosin heavy chain binding 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0044548 S100 protein binding 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0070742 C2H2 zinc finger domain binding 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0071933 Arp2/3 complex binding 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0098599 palmitoyl hydrolase activity 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:1901612 cardiolipin binding 2/1975 14/18639 0.142857142857143 1.34820976491863 0.445738310083178 0.871413829520966 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1975 23/18639 0.130434782608696 1.23097413318657 0.446298281506546 0.871413829520966 GO:0004602 glutathione peroxidase activity 3/1975 23/18639 0.130434782608696 1.23097413318657 0.446298281506546 0.871413829520966 GO:0016849 phosphorus-oxygen lyase activity 3/1975 23/18639 0.130434782608696 1.23097413318657 0.446298281506546 0.871413829520966 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/1975 23/18639 0.130434782608696 1.23097413318657 0.446298281506546 0.871413829520966 GO:0016279 protein-lysine N-methyltransferase activity 8/1975 69/18639 0.115942028985507 1.09419922949917 0.45012715976034 0.87745376077465 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1975 60/18639 0.116666666666667 1.10103797468354 0.454127828820613 0.883808319384977 GO:0003774 cytoskeletal motor activity 17/1975 153/18639 0.111111111111111 1.04860759493671 0.456212197089989 0.886418812912633 GO:0005010 insulin-like growth factor receptor activity 6/1975 51/18639 0.117647058823529 1.11029039463887 0.458480045485528 0.887932945234147 GO:0005030 neurotrophin receptor activity 6/1975 51/18639 0.117647058823529 1.11029039463887 0.458480045485528 0.887932945234147 GO:0016829 lyase activity 22/1975 200/18639 0.11 1.03812151898734 0.459879487443196 0.888584160164596 GO:0033293 monocarboxylic acid binding 9/1975 79/18639 0.113924050632911 1.07515462265663 0.461978202660379 0.888584160164596 GO:0033218 amide binding 27/1975 247/18639 0.109311740890688 1.03162609542356 0.462256976430959 0.888584160164596 GO:0008307 structural constituent of muscle 5/1975 42/18639 0.119047619047619 1.12350813743219 0.463285287193947 0.888584160164596 GO:0048487 beta-tubulin binding 5/1975 42/18639 0.119047619047619 1.12350813743219 0.463285287193947 0.888584160164596 GO:0051879 Hsp90 protein binding 5/1975 42/18639 0.119047619047619 1.12350813743219 0.463285287193947 0.888584160164596 GO:0016278 lysine N-methyltransferase activity 8/1975 70/18639 0.114285714285714 1.0785678119349 0.466687908915364 0.890877260563061 GO:0097110 scaffold protein binding 8/1975 70/18639 0.114285714285714 1.0785678119349 0.466687908915364 0.890877260563061 GO:0008170 N-methyltransferase activity 11/1975 98/18639 0.112244897959184 1.05930767243606 0.467622269297355 0.890877260563061 GO:0019956 chemokine binding 4/1975 33/18639 0.121212121212121 1.14393555811277 0.468698279832232 0.890877260563061 GO:0030296 protein tyrosine kinase activator activity 4/1975 33/18639 0.121212121212121 1.14393555811277 0.468698279832232 0.890877260563061 GO:0015026 coreceptor activity 7/1975 61/18639 0.114754098360656 1.08298817181988 0.471891111149775 0.890877260563061 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0019957 C-C chemokine binding 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0070840 dynein complex binding 3/1975 24/18639 0.125 1.1796835443038 0.474962625606436 0.890877260563061 GO:0030159 signaling receptor complex adaptor activity 6/1975 52/18639 0.115384615384615 1.08893865628043 0.477746043429226 0.890877260563061 GO:0140104 molecular carrier activity 27/1975 249/18639 0.108433734939759 1.02333994204667 0.479824751625022 0.890877260563061 GO:0004519 endonuclease activity 14/1975 127/18639 0.110236220472441 1.04035084222067 0.479963560830763 0.890877260563061 GO:0008252 nucleotidase activity 2/1975 15/18639 0.133333333333333 1.25832911392405 0.482402942433979 0.890877260563061 GO:0015929 hexosaminidase activity 2/1975 15/18639 0.133333333333333 1.25832911392405 0.482402942433979 0.890877260563061 GO:0030553 cGMP binding 2/1975 15/18639 0.133333333333333 1.25832911392405 0.482402942433979 0.890877260563061 GO:0033130 acetylcholine receptor binding 2/1975 15/18639 0.133333333333333 1.25832911392405 0.482402942433979 0.890877260563061 GO:0042809 nuclear vitamin D receptor binding 2/1975 15/18639 0.133333333333333 1.25832911392405 0.482402942433979 0.890877260563061 GO:0120283 protein serine/threonine kinase binding 2/1975 15/18639 0.133333333333333 1.25832911392405 0.482402942433979 0.890877260563061 GO:0140776 protein-containing complex destabilizing activity 2/1975 15/18639 0.133333333333333 1.25832911392405 0.482402942433979 0.890877260563061 GO:0008200 ion channel inhibitor activity 5/1975 43/18639 0.116279069767442 1.09738004121283 0.484505118948322 0.891997850162574 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1975 43/18639 0.116279069767442 1.09738004121283 0.484505118948322 0.891997850162574 GO:0015020 glucuronosyltransferase activity 4/1975 34/18639 0.117647058823529 1.11029039463887 0.492607606583658 0.905517526431902 GO:0005003 ephrin receptor activity 6/1975 53/18639 0.113207547169811 1.06839264389778 0.496803566359434 0.906248707441597 GO:0005005 transmembrane-ephrin receptor activity 6/1975 53/18639 0.113207547169811 1.06839264389778 0.496803566359434 0.906248707441597 GO:0016860 intramolecular oxidoreductase activity 6/1975 53/18639 0.113207547169811 1.06839264389778 0.496803566359434 0.906248707441597 GO:0017046 peptide hormone binding 6/1975 53/18639 0.113207547169811 1.06839264389778 0.496803566359434 0.906248707441597 GO:1901505 carbohydrate derivative transmembrane transporter activity 6/1975 53/18639 0.113207547169811 1.06839264389778 0.496803566359434 0.906248707441597 GO:0015271 outward rectifier potassium channel activity 3/1975 25/18639 0.12 1.13249620253165 0.502920177660026 0.91182944065108 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1975 25/18639 0.12 1.13249620253165 0.502920177660026 0.91182944065108 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/1975 25/18639 0.12 1.13249620253165 0.502920177660026 0.91182944065108 GO:0019707 protein-cysteine S-acyltransferase activity 3/1975 25/18639 0.12 1.13249620253165 0.502920177660026 0.91182944065108 GO:0015485 cholesterol binding 6/1975 54/18639 0.111111111111111 1.04860759493671 0.51561698719384 0.925647869114697 GO:0050661 NADP binding 6/1975 54/18639 0.111111111111111 1.04860759493671 0.51561698719384 0.925647869114697 GO:0043178 alcohol binding 10/1975 92/18639 0.108695652173913 1.02581177765548 0.515814914013552 0.925647869114697 GO:0005154 epidermal growth factor receptor binding 4/1975 35/18639 0.114285714285714 1.0785678119349 0.516052679795385 0.925647869114697 GO:0003688 DNA replication origin binding 2/1975 16/18639 0.125 1.1796835443038 0.517524835456415 0.925647869114697 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1975 16/18639 0.125 1.1796835443038 0.517524835456415 0.925647869114697 GO:0017070 U6 snRNA binding 2/1975 16/18639 0.125 1.1796835443038 0.517524835456415 0.925647869114697 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1975 16/18639 0.125 1.1796835443038 0.517524835456415 0.925647869114697 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/1975 16/18639 0.125 1.1796835443038 0.517524835456415 0.925647869114697 GO:0008009 chemokine activity 5/1975 45/18639 0.111111111111111 1.04860759493671 0.525994618061335 0.936883922757393 GO:0042605 peptide antigen binding 5/1975 45/18639 0.111111111111111 1.04860759493671 0.525994618061335 0.936883922757393 GO:0140597 protein carrier chaperone 20/1975 188/18639 0.106382978723404 1.00398599515217 0.527697170882925 0.936883922757393 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/1975 26/18639 0.115384615384615 1.08893865628043 0.530089394686706 0.936883922757393 GO:0004529 DNA exonuclease activity 3/1975 26/18639 0.115384615384615 1.08893865628043 0.530089394686706 0.936883922757393 GO:0030507 spectrin binding 3/1975 26/18639 0.115384615384615 1.08893865628043 0.530089394686706 0.936883922757393 GO:0050681 nuclear androgen receptor binding 3/1975 26/18639 0.115384615384615 1.08893865628043 0.530089394686706 0.936883922757393 GO:0097602 cullin family protein binding 3/1975 26/18639 0.115384615384615 1.08893865628043 0.530089394686706 0.936883922757393 GO:0045505 dynein intermediate chain binding 4/1975 36/18639 0.111111111111111 1.04860759493671 0.538978976888035 0.951186271342347 GO:0120013 lipid transfer activity 7/1975 65/18639 0.107692307692308 1.01634274586173 0.541167010990333 0.953636992779125 GO:0016853 isomerase activity 19/1975 180/18639 0.105555555555556 0.996177215189873 0.543104397819511 0.955473631952709 GO:0004180 carboxypeptidase activity 5/1975 46/18639 0.108695652173913 1.02581177765548 0.546181234932839 0.955473631952709 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0004550 nucleoside diphosphate kinase activity 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0004659 prenyltransferase activity 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0009881 photoreceptor activity 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0015278 intracellularly gated calcium channel activity 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0030169 low-density lipoprotein particle binding 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0036041 long-chain fatty acid binding 2/1975 17/18639 0.117647058823529 1.11029039463887 0.551019160757304 0.955473631952709 GO:0004364 glutathione transferase activity 3/1975 27/18639 0.111111111111111 1.04860759493671 0.556404327919002 0.959234628912384 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/1975 27/18639 0.111111111111111 1.04860759493671 0.556404327919002 0.959234628912384 GO:0005104 fibroblast growth factor receptor binding 3/1975 27/18639 0.111111111111111 1.04860759493671 0.556404327919002 0.959234628912384 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1975 27/18639 0.111111111111111 1.04860759493671 0.556404327919002 0.959234628912384 GO:0030551 cyclic nucleotide binding 4/1975 37/18639 0.108108108108108 1.02026684912761 0.561339603370272 0.966346532208851 GO:1990518 single-stranded 3'-5' DNA helicase activity 5/1975 47/18639 0.106382978723404 1.00398599515217 0.565947836910197 0.972875748463783 GO:0004601 peroxidase activity 6/1975 57/18639 0.105263157894737 0.993417721518987 0.570279553993899 0.978911522179456 GO:0016500 protein-hormone receptor activity 7/1975 67/18639 0.104477611940299 0.986004156433025 0.574373166118735 0.981748270051981 GO:0050698 proteoglycan sulfotransferase activity 3/1975 28/18639 0.107142857142857 1.01115732368897 0.581813253778891 0.981748270051981 GO:0097718 disordered domain specific binding 3/1975 28/18639 0.107142857142857 1.01115732368897 0.581813253778891 0.981748270051981 GO:0008409 5'-3' exonuclease activity 2/1975 18/18639 0.111111111111111 1.04860759493671 0.58283636410847 0.981748270051981 GO:0008525 phosphatidylcholine transporter activity 2/1975 18/18639 0.111111111111111 1.04860759493671 0.58283636410847 0.981748270051981 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1975 18/18639 0.111111111111111 1.04860759493671 0.58283636410847 0.981748270051981 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1975 18/18639 0.111111111111111 1.04860759493671 0.58283636410847 0.981748270051981 GO:0035615 clathrin adaptor activity 2/1975 18/18639 0.111111111111111 1.04860759493671 0.58283636410847 0.981748270051981 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1975 18/18639 0.111111111111111 1.04860759493671 0.58283636410847 0.981748270051981 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1975 18/18639 0.111111111111111 1.04860759493671 0.58283636410847 0.981748270051981 GO:0005109 frizzled binding 4/1975 38/18639 0.105263157894737 0.993417721518987 0.583094924467884 0.981748270051981 GO:0032266 phosphatidylinositol-3-phosphate binding 5/1975 48/18639 0.104166666666667 0.983069620253165 0.585263898743718 0.981748270051981 GO:0043138 3'-5' DNA helicase activity 5/1975 48/18639 0.104166666666667 0.983069620253165 0.585263898743718 0.981748270051981 GO:0140693 molecular condensate scaffold activity 5/1975 48/18639 0.104166666666667 0.983069620253165 0.585263898743718 0.981748270051981 GO:0005548 phospholipid transporter activity 7/1975 68/18639 0.102941176470588 0.97150409530901 0.590540828696246 0.981748270051981 GO:0005004 GPI-linked ephrin receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0005008 hepatocyte growth factor receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0005009 insulin receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0005011 macrophage colony-stimulating factor receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0005020 stem cell factor receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0008288 boss receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0035254 glutamate receptor binding 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0036332 placental growth factor receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0038062 protein tyrosine kinase collagen receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0060175 brain-derived neurotrophic factor receptor activity 5/1975 49/18639 0.102040816326531 0.963006974941875 0.604103059260387 0.981748270051981 GO:0001786 phosphatidylserine binding 6/1975 59/18639 0.101694915254237 0.959742544518344 0.604976797918708 0.981748270051981 GO:0015459 potassium channel regulator activity 6/1975 59/18639 0.101694915254237 0.959742544518344 0.604976797918708 0.981748270051981 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/1975 59/18639 0.101694915254237 0.959742544518344 0.604976797918708 0.981748270051981 GO:0004181 metallocarboxypeptidase activity 3/1975 29/18639 0.103448275862069 0.97628982976866 0.606277312021359 0.981748270051981 GO:0016417 S-acyltransferase activity 3/1975 29/18639 0.103448275862069 0.97628982976866 0.606277312021359 0.981748270051981 GO:0051861 glycolipid binding 3/1975 29/18639 0.103448275862069 0.97628982976866 0.606277312021359 0.981748270051981 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 17/1975 167/18639 0.101796407185629 0.960700371409081 0.607047880298131 0.981748270051981 GO:0005229 intracellularly calcium-gated chloride channel activity 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0008574 plus-end-directed microtubule motor activity 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0015245 fatty acid transmembrane transporter activity 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0031420 alkali metal ion binding 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0043395 heparan sulfate proteoglycan binding 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0140036 ubiquitin-modified protein reader activity 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0141147 intracellularly calcium-gated channel activity 2/1975 19/18639 0.105263157894737 0.993417721518987 0.612955648866109 0.981748270051981 GO:0070851 growth factor receptor binding 14/1975 139/18639 0.100719424460432 0.950536381021765 0.62069289604363 0.981748270051981 GO:0005006 epidermal growth factor receptor activity 5/1975 50/18639 0.1 0.943746835443038 0.622442949932272 0.981748270051981 GO:0005007 fibroblast growth factor receptor activity 5/1975 50/18639 0.1 0.943746835443038 0.622442949932272 0.981748270051981 GO:0005017 platelet-derived growth factor receptor activity 5/1975 50/18639 0.1 0.943746835443038 0.622442949932272 0.981748270051981 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1975 50/18639 0.1 0.943746835443038 0.622442949932272 0.981748270051981 GO:0032451 demethylase activity 4/1975 40/18639 0.1 0.943746835443038 0.624664935076943 0.981748270051981 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/1975 40/18639 0.1 0.943746835443038 0.624664935076943 0.981748270051981 GO:0016769 transferase activity, transferring nitrogenous groups 3/1975 30/18639 0.1 0.943746835443038 0.629769176272175 0.981748270051981 GO:0032452 histone demethylase activity 3/1975 30/18639 0.1 0.943746835443038 0.629769176272175 0.981748270051981 GO:0033612 receptor serine/threonine kinase binding 3/1975 30/18639 0.1 0.943746835443038 0.629769176272175 0.981748270051981 GO:0043177 organic acid binding 19/1975 189/18639 0.100529100529101 0.948740204942736 0.631361940512585 0.981748270051981 GO:0016757 glycosyltransferase activity 27/1975 267/18639 0.101123595505618 0.954350732470488 0.631613405708124 0.981748270051981 GO:0015101 organic cation transmembrane transporter activity 8/1975 81/18639 0.0987654320987654 0.932095639943741 0.636870715320158 0.981748270051981 GO:0140299 molecular sensor activity 7/1975 71/18639 0.0985915492957746 0.930454626493136 0.63709565233696 0.981748270051981 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 6/1975 61/18639 0.0983606557377049 0.928275575845611 0.638084705394478 0.981748270051981 GO:0016836 hydro-lyase activity 6/1975 61/18639 0.0983606557377049 0.928275575845611 0.638084705394478 0.981748270051981 GO:0005021 vascular endothelial growth factor receptor activity 5/1975 51/18639 0.0980392156862745 0.92524199553239 0.64026500476344 0.981748270051981 GO:0016597 amino acid binding 5/1975 51/18639 0.0980392156862745 0.92524199553239 0.64026500476344 0.981748270051981 GO:0030544 Hsp70 protein binding 5/1975 51/18639 0.0980392156862745 0.92524199553239 0.64026500476344 0.981748270051981 GO:0001972 retinoic acid binding 2/1975 20/18639 0.1 0.943746835443038 0.641379443274295 0.981748270051981 GO:0016505 peptidase activator activity involved in apoptotic process 2/1975 20/18639 0.1 0.943746835443038 0.641379443274295 0.981748270051981 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1975 20/18639 0.1 0.943746835443038 0.641379443274295 0.981748270051981 GO:0052745 inositol phosphate phosphatase activity 2/1975 20/18639 0.1 0.943746835443038 0.641379443274295 0.981748270051981 GO:0140939 histone H4 methyltransferase activity 2/1975 20/18639 0.1 0.943746835443038 0.641379443274295 0.981748270051981 GO:0140318 protein transporter activity 4/1975 41/18639 0.0975609756097561 0.920728619944427 0.644432855785821 0.981748270051981 GO:0052689 carboxylic ester hydrolase activity 9/1975 92/18639 0.0978260869565217 0.923230599889929 0.650317875880138 0.981748270051981 GO:0005200 structural constituent of cytoskeleton 11/1975 112/18639 0.0982142857142857 0.926894213381555 0.650648441460366 0.981748270051981 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 12/1975 122/18639 0.0983606557377049 0.928275575845611 0.651238860791308 0.981748270051981 GO:0016411 acylglycerol O-acyltransferase activity 3/1975 31/18639 0.0967741935483871 0.913303389138424 0.65227177556404 0.981748270051981 GO:0017147 Wnt-protein binding 3/1975 31/18639 0.0967741935483871 0.913303389138424 0.65227177556404 0.981748270051981 GO:0047499 calcium-independent phospholipase A2 activity 3/1975 31/18639 0.0967741935483871 0.913303389138424 0.65227177556404 0.981748270051981 GO:0140457 protein demethylase activity 3/1975 31/18639 0.0967741935483871 0.913303389138424 0.65227177556404 0.981748270051981 GO:0019894 kinesin binding 4/1975 42/18639 0.0952380952380952 0.89880650994575 0.663501020900755 0.981748270051981 GO:0031492 nucleosomal DNA binding 4/1975 42/18639 0.0952380952380952 0.89880650994575 0.663501020900755 0.981748270051981 GO:0042056 chemoattractant activity 4/1975 42/18639 0.0952380952380952 0.89880650994575 0.663501020900755 0.981748270051981 GO:0061775 cohesin loader activity 15/1975 153/18639 0.0980392156862745 0.92524199553239 0.664077029354715 0.981748270051981 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1975 21/18639 0.0952380952380952 0.89880650994575 0.668128716468269 0.981748270051981 GO:0005248 voltage-gated sodium channel activity 2/1975 21/18639 0.0952380952380952 0.89880650994575 0.668128716468269 0.981748270051981 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1975 21/18639 0.0952380952380952 0.89880650994575 0.668128716468269 0.981748270051981 GO:0140312 cargo adaptor activity 2/1975 21/18639 0.0952380952380952 0.89880650994575 0.668128716468269 0.981748270051981 GO:1904047 S-adenosyl-L-methionine binding 2/1975 21/18639 0.0952380952380952 0.89880650994575 0.668128716468269 0.981748270051981 GO:0051087 protein-folding chaperone binding 13/1975 134/18639 0.0970149253731343 0.91557528811638 0.673452855747413 0.981748270051981 GO:0071813 lipoprotein particle binding 3/1975 32/18639 0.09375 0.884762658227848 0.673777080098247 0.981748270051981 GO:0071814 protein-lipid complex binding 3/1975 32/18639 0.09375 0.884762658227848 0.673777080098247 0.981748270051981 GO:0000182 rDNA binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0004090 carbonyl reductase (NADPH) activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0004935 adrenergic receptor activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0005031 tumor necrosis factor receptor activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0005131 growth hormone receptor binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0005522 profilin binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0008190 eukaryotic initiation factor 4E binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0008401 retinoic acid 4-hydroxylase activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0015203 polyamine transmembrane transporter activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0015279 store-operated calcium channel activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0016783 sulfurtransferase activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0030957 Tat protein binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0031419 cobalamin binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0042166 acetylcholine binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0042975 peroxisome proliferator activated receptor binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0045322 unmethylated CpG binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0051864 histone H3K36 demethylase activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0070097 delta-catenin binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0140940 histone H2A methyltransferase activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0140999 histone H3K4 trimethyltransferase activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0141109 transporter activator activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:1990259 histone H2AQ104 methyltransferase activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:1990757 ubiquitin ligase activator activity 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:1990763 arrestin family protein binding 1/1975 10/18639 0.1 0.943746835443038 0.673831382714861 0.981748270051981 GO:0005544 calcium-dependent phospholipid binding 5/1975 53/18639 0.0943396226415094 0.890327203248149 0.674299119470225 0.981748270051981 GO:0038064 collagen receptor activity 5/1975 53/18639 0.0943396226415094 0.890327203248149 0.674299119470225 0.981748270051981 GO:0061135 endopeptidase regulator activity 18/1975 184/18639 0.0978260869565217 0.923230599889929 0.675872252355091 0.981748270051981 GO:0031491 nucleosome binding 7/1975 74/18639 0.0945945945945946 0.892733492986658 0.680455599172414 0.981748270051981 GO:0004386 helicase activity 15/1975 155/18639 0.0967741935483871 0.913303389138424 0.683738525738121 0.981748270051981 GO:0008649 rRNA methyltransferase activity 2/1975 22/18639 0.0909090909090909 0.85795166858458 0.69323902557394 0.981748270051981 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1975 22/18639 0.0909090909090909 0.85795166858458 0.69323902557394 0.981748270051981 GO:0140035 ubiquitin-like protein reader activity 2/1975 22/18639 0.0909090909090909 0.85795166858458 0.69323902557394 0.981748270051981 GO:0019239 deaminase activity 3/1975 33/18639 0.0909090909090909 0.85795166858458 0.694284960124849 0.981748270051981 GO:0061134 peptidase regulator activity 22/1975 226/18639 0.0973451327433628 0.918691609723311 0.695560827409717 0.981748270051981 GO:0031406 carboxylic acid binding 18/1975 187/18639 0.0962566844919786 0.908419413795438 0.702228976316375 0.981748270051981 GO:0016758 hexosyltransferase activity 19/1975 197/18639 0.0964467005076142 0.910212683929833 0.70236758040212 0.981748270051981 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/1975 86/18639 0.0930232558139535 0.877904032970268 0.703253349792059 0.981748270051981 GO:0016209 antioxidant activity 8/1975 86/18639 0.0930232558139535 0.877904032970268 0.703253349792059 0.981748270051981 GO:0001851 complement component C3b binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0004016 adenylate cyclase activity 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0008199 ferric iron binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0008432 JUN kinase binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0019206 nucleoside kinase activity 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0034511 U3 snoRNA binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0034713 type I transforming growth factor beta receptor binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0035252 UDP-xylosyltransferase activity 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0042285 xylosyltransferase activity 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0042608 T cell receptor binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0048407 platelet-derived growth factor binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0050786 RAGE receptor binding 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0180030 inositol phosphate kinase activity 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:1990948 ubiquitin ligase inhibitor activity 1/1975 11/18639 0.0909090909090909 0.85795166858458 0.708410963966574 0.981748270051981 GO:0005319 lipid transporter activity 17/1975 178/18639 0.0955056179775281 0.901331247333239 0.71095252142837 0.981748270051981 GO:0008376 acetylgalactosaminyltransferase activity 3/1975 34/18639 0.0882352941176471 0.832717795979151 0.713802123370771 0.981748270051981 GO:0016831 carboxy-lyase activity 3/1975 34/18639 0.0882352941176471 0.832717795979151 0.713802123370771 0.981748270051981 GO:0016493 C-C chemokine receptor activity 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:0017134 fibroblast growth factor binding 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:0031681 G-protein beta-subunit binding 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:0071617 lysophospholipid acyltransferase activity 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:0099186 structural constituent of postsynapse 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:0140102 catalytic activity, acting on a rRNA 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1975 23/18639 0.0869565217391304 0.820649422124381 0.716757191675596 0.981748270051981 GO:0051015 actin filament binding 20/1975 209/18639 0.0956937799043062 0.903107019562716 0.718673597822205 0.981748270051981 GO:0008173 RNA methyltransferase activity 6/1975 67/18639 0.0895522388059701 0.845146419799735 0.726869778302354 0.981748270051981 GO:0004623 phospholipase A2 activity 3/1975 35/18639 0.0857142857142857 0.808925858951175 0.732341133705963 0.981748270051981 GO:0016798 hydrolase activity, acting on glycosyl bonds 12/1975 130/18639 0.0923076923076923 0.871150925024343 0.735171281040792 0.981748270051981 GO:0004622 lysophospholipase activity 2/1975 24/18639 0.0833333333333333 0.786455696202532 0.738738515863702 0.981748270051981 GO:0005315 phosphate transmembrane transporter activity 2/1975 24/18639 0.0833333333333333 0.786455696202532 0.738738515863702 0.981748270051981 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1975 24/18639 0.0833333333333333 0.786455696202532 0.738738515863702 0.981748270051981 GO:0030552 cAMP binding 2/1975 24/18639 0.0833333333333333 0.786455696202532 0.738738515863702 0.981748270051981 GO:0048027 mRNA 5'-UTR binding 2/1975 24/18639 0.0833333333333333 0.786455696202532 0.738738515863702 0.981748270051981 GO:0003995 acyl-CoA dehydrogenase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0004126 cytidine deaminase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0004300 enoyl-CoA hydratase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0004859 phospholipase inhibitor activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0005049 nuclear export signal receptor activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0005247 voltage-gated chloride channel activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0008179 adenylate cyclase binding 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0015132 prostaglandin transmembrane transporter activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0016208 AMP binding 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0016273 arginine N-methyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0016274 protein-arginine N-methyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0016423 tRNA (guanine) methyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0016801 hydrolase activity, acting on ether bonds 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0016803 ether hydrolase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0016840 carbon-nitrogen lyase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0034452 dynactin binding 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0036009 protein-glutamine N-methyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0097371 MDM2/MDM4 family protein binding 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0097677 STAT family protein binding 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:1990817 poly(A) RNA polymerase activity 1/1975 12/18639 0.0833333333333333 0.786455696202532 0.739326163996959 0.981748270051981 GO:0000510 H3-H4 histone complex chaperone activity 14/1975 151/18639 0.0927152317880795 0.874997065973678 0.740228510701227 0.981748270051981 GO:0140584 chromatin extrusion motor activity 14/1975 151/18639 0.0927152317880795 0.874997065973678 0.740228510701227 0.981748270051981 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 14/1975 151/18639 0.0927152317880795 0.874997065973678 0.740228510701227 0.981748270051981 GO:0140849 ATP-dependent H2AZ histone chaperone activity 14/1975 151/18639 0.0927152317880795 0.874997065973678 0.740228510701227 0.981748270051981 GO:0016835 carbon-oxygen lyase activity 7/1975 79/18639 0.0886075949367089 0.836231373177375 0.745046212916199 0.981748270051981 GO:0061749 forked DNA-dependent helicase activity 4/1975 47/18639 0.0851063829787234 0.803188796121734 0.74815190672695 0.981748270051981 GO:0015616 DNA translocase activity 14/1975 152/18639 0.0921052631578947 0.869240506329114 0.748976048175314 0.981748270051981 GO:0140674 ATP-dependent histone chaperone activity 14/1975 152/18639 0.0921052631578947 0.869240506329114 0.748976048175314 0.981748270051981 GO:0017116 single-stranded DNA helicase activity 5/1975 58/18639 0.0862068965517241 0.81357485814055 0.749660985091173 0.981748270051981 GO:0016409 palmitoyltransferase activity 3/1975 36/18639 0.0833333333333333 0.786455696202532 0.749919511598502 0.981748270051981 GO:0008168 methyltransferase activity 19/1975 204/18639 0.0931372549019608 0.878979895755771 0.757436077948466 0.981748270051981 GO:0005251 delayed rectifier potassium channel activity 2/1975 25/18639 0.08 0.75499746835443 0.759244458316195 0.981748270051981 GO:0008483 transaminase activity 2/1975 25/18639 0.08 0.75499746835443 0.759244458316195 0.981748270051981 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1975 25/18639 0.08 0.75499746835443 0.759244458316195 0.981748270051981 GO:0047617 fatty acyl-CoA hydrolase activity 2/1975 25/18639 0.08 0.75499746835443 0.759244458316195 0.981748270051981 GO:0120020 cholesterol transfer activity 2/1975 25/18639 0.08 0.75499746835443 0.759244458316195 0.981748270051981 GO:1901681 sulfur compound binding 26/1975 275/18639 0.0945454545454545 0.892269735327963 0.759916219675987 0.981748270051981 GO:0072341 modified amino acid binding 8/1975 91/18639 0.0879120879120879 0.829667547642231 0.761233541406922 0.981748270051981 GO:0009378 four-way junction helicase activity 4/1975 48/18639 0.0833333333333333 0.786455696202532 0.762959907452698 0.981748270051981 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/1975 48/18639 0.0833333333333333 0.786455696202532 0.762959907452698 0.981748270051981 GO:0036121 double-stranded DNA helicase activity 4/1975 48/18639 0.0833333333333333 0.786455696202532 0.762959907452698 0.981748270051981 GO:0036002 pre-mRNA binding 5/1975 59/18639 0.0847457627118644 0.799785453765286 0.763057669088623 0.981748270051981 GO:0140713 histone chaperone activity 15/1975 164/18639 0.0914634146341463 0.863183081197901 0.763590425832139 0.981748270051981 GO:0015171 amino acid transmembrane transporter activity 9/1975 102/18639 0.0882352941176471 0.832717795979151 0.765922330103818 0.981748270051981 GO:0023023 MHC protein complex binding 3/1975 37/18639 0.0810810810810811 0.765200136845707 0.766558915265699 0.981748270051981 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0005172 vascular endothelial growth factor receptor binding 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0008035 high-density lipoprotein particle binding 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0017154 semaphorin receptor activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0019104 DNA N-glycosylase activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0019855 calcium channel inhibitor activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0031432 titin binding 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0035673 oligopeptide transmembrane transporter activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0051011 microtubule minus-end binding 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0071714 icosanoid transmembrane transporter activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0071837 HMG box domain binding 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0089720 caspase binding 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0140333 glycerophospholipid flippase activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:1901338 catecholamine binding 1/1975 13/18639 0.0769230769230769 0.725959104186952 0.766965119604733 0.981748270051981 GO:0008194 UDP-glycosyltransferase activity 13/1975 145/18639 0.0896551724137931 0.846117852466172 0.77693950690225 0.985209626554177 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1975 26/18639 0.0769230769230769 0.725959104186952 0.778340713618652 0.985209626554177 GO:0004950 chemokine receptor activity 2/1975 26/18639 0.0769230769230769 0.725959104186952 0.778340713618652 0.985209626554177 GO:0008198 ferrous iron binding 2/1975 26/18639 0.0769230769230769 0.725959104186952 0.778340713618652 0.985209626554177 GO:0016289 acyl-CoA hydrolase activity 2/1975 26/18639 0.0769230769230769 0.725959104186952 0.778340713618652 0.985209626554177 GO:0034237 protein kinase A regulatory subunit binding 2/1975 26/18639 0.0769230769230769 0.725959104186952 0.778340713618652 0.985209626554177 GO:0070006 metalloaminopeptidase activity 2/1975 26/18639 0.0769230769230769 0.725959104186952 0.778340713618652 0.985209626554177 GO:0120014 phospholipid transfer activity 2/1975 26/18639 0.0769230769230769 0.725959104186952 0.778340713618652 0.985209626554177 GO:0005501 retinoid binding 3/1975 38/18639 0.0789473684210526 0.745063291139241 0.782284400191226 0.985209626554177 GO:0019840 isoprenoid binding 3/1975 38/18639 0.0789473684210526 0.745063291139241 0.782284400191226 0.985209626554177 GO:0008514 organic anion transmembrane transporter activity 25/1975 269/18639 0.0929368029739777 0.877088137028846 0.785158842134001 0.985209626554177 GO:0004065 arylsulfatase activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0008494 translation activator activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0015926 glucosidase activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0031404 chloride ion binding 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0032454 histone H3K9 demethylase activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0042043 neurexin family protein binding 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0042813 Wnt receptor activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0046030 inositol trisphosphate phosphatase activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0098847 sequence-specific single stranded DNA binding 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:1901474 azole transmembrane transporter activity 1/1975 14/18639 0.0714285714285714 0.674104882459313 0.791674874183314 0.985209626554177 GO:0005044 scavenger receptor activity 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0008320 protein transmembrane transporter activity 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0008395 steroid hydroxylase activity 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0015252 proton channel activity 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0023026 MHC class II protein complex binding 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0035255 ionotropic glutamate receptor binding 2/1975 27/18639 0.0740740740740741 0.699071729957806 0.796095624474624 0.985209626554177 GO:0140658 ATP-dependent chromatin remodeler activity 14/1975 158/18639 0.0886075949367089 0.836231373177375 0.797318674550503 0.985606610818468 GO:0030414 peptidase inhibitor activity 15/1975 169/18639 0.0887573964497041 0.837645120215714 0.801561305982744 0.985606610818468 GO:0016830 carbon-carbon lyase activity 4/1975 51/18639 0.0784313725490196 0.740193596425912 0.803315538204741 0.985606610818468 GO:0004896 cytokine receptor activity 8/1975 96/18639 0.0833333333333333 0.786455696202532 0.81065068202996 0.985606610818468 GO:0003689 DNA clamp loader activity 14/1975 160/18639 0.0875 0.825778481012658 0.811857208191813 0.985606610818468 GO:0016866 intramolecular transferase activity 2/1975 28/18639 0.0714285714285714 0.674104882459313 0.812578883758911 0.985606610818468 GO:0046625 sphingolipid binding 2/1975 28/18639 0.0714285714285714 0.674104882459313 0.812578883758911 0.985606610818468 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1975 28/18639 0.0714285714285714 0.674104882459313 0.812578883758911 0.985606610818468 GO:0141052 histone H3 demethylase activity 2/1975 28/18639 0.0714285714285714 0.674104882459313 0.812578883758911 0.985606610818468 GO:0004559 alpha-mannosidase activity 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0017081 chloride channel regulator activity 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0034483 heparan sulfate sulfotransferase activity 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0045504 dynein heavy chain binding 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0048531 beta-1,3-galactosyltransferase activity 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0050700 CARD domain binding 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0050780 dopamine receptor binding 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0140161 monocarboxylate:sodium symporter activity 1/1975 15/18639 0.0666666666666667 0.629164556962025 0.813765726451124 0.985606610818468 GO:0022804 active transmembrane transporter activity 43/1975 457/18639 0.0940919037199125 0.887989363764784 0.818229879496548 0.989436355409589 GO:0004866 endopeptidase inhibitor activity 14/1975 161/18639 0.0869565217391304 0.820649422124381 0.818834647347312 0.989436355409589 GO:0001530 lipopolysaccharide binding 3/1975 41/18639 0.0731707317073171 0.69054646495832 0.8242653785077 0.989436355409589 GO:0051018 protein kinase A binding 4/1975 53/18639 0.0754716981132075 0.712261762598519 0.826985837622666 0.989436355409589 GO:0035250 UDP-galactosyltransferase activity 2/1975 29/18639 0.0689655172413793 0.65085988651244 0.827860481665397 0.989436355409589 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/1975 29/18639 0.0689655172413793 0.65085988651244 0.827860481665397 0.989436355409589 GO:0099604 ligand-gated calcium channel activity 2/1975 29/18639 0.0689655172413793 0.65085988651244 0.827860481665397 0.989436355409589 GO:0042626 ATPase-coupled transmembrane transporter activity 8/1975 98/18639 0.0816326530612245 0.7704055799535 0.828086110023758 0.989436355409589 GO:0008081 phosphoric diester hydrolase activity 7/1975 87/18639 0.0804597701149425 0.759336534264513 0.828099134668527 0.989436355409589 GO:0016741 transferase activity, transferring one-carbon groups 19/1975 215/18639 0.0883720930232558 0.834008831321754 0.829593164638535 0.989436355409589 GO:0038024 cargo receptor activity 5/1975 65/18639 0.0769230769230769 0.725959104186952 0.832211012656991 0.989436355409589 GO:0015378 sodium:chloride symporter activity 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0015923 mannosidase activity 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0019841 retinol binding 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0055102 lipase inhibitor activity 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0140327 flippase activity 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0140328 floppase activity 1/1975 16/18639 0.0625 0.589841772151899 0.833515119184104 0.989436355409589 GO:0004222 metalloendopeptidase activity 9/1975 110/18639 0.0818181818181818 0.772156501726122 0.836691895710433 0.990947764702682 GO:0001965 G-protein alpha-subunit binding 2/1975 30/18639 0.0666666666666667 0.629164556962025 0.842009860622056 0.990947764702682 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1975 30/18639 0.0666666666666667 0.629164556962025 0.842009860622056 0.990947764702682 GO:0048019 receptor antagonist activity 2/1975 30/18639 0.0666666666666667 0.629164556962025 0.842009860622056 0.990947764702682 GO:0070566 adenylyltransferase activity 2/1975 30/18639 0.0666666666666667 0.629164556962025 0.842009860622056 0.990947764702682 GO:0098918 structural constituent of synapse 2/1975 30/18639 0.0666666666666667 0.629164556962025 0.842009860622056 0.990947764702682 GO:1902936 phosphatidylinositol bisphosphate binding 9/1975 111/18639 0.0810810810810811 0.765200136845707 0.844229533725755 0.990947764702682 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0016805 dipeptidase activity 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0019198 transmembrane receptor protein phosphatase activity 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0030548 acetylcholine receptor regulator activity 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0031489 myosin V binding 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0045125 bioactive lipid receptor activity 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0045236 CXCR chemokine receptor binding 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0070402 NADPH binding 1/1975 17/18639 0.0588235294117647 0.555145197319434 0.851171116585779 0.990947764702682 GO:0046943 carboxylic acid transmembrane transporter activity 16/1975 188/18639 0.0851063829787234 0.803188796121734 0.854968113525156 0.990947764702682 GO:0005184 neuropeptide hormone activity 2/1975 31/18639 0.0645161290322581 0.608868926092283 0.85509524579847 0.990947764702682 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1975 31/18639 0.0645161290322581 0.608868926092283 0.85509524579847 0.990947764702682 GO:0070325 lipoprotein particle receptor binding 2/1975 31/18639 0.0645161290322581 0.608868926092283 0.85509524579847 0.990947764702682 GO:0072349 modified amino acid transmembrane transporter activity 2/1975 31/18639 0.0645161290322581 0.608868926092283 0.85509524579847 0.990947764702682 GO:0016790 thiolester hydrolase activity 3/1975 44/18639 0.0681818181818182 0.643463751438435 0.859122950919612 0.990947764702682 GO:0030547 signaling receptor inhibitor activity 3/1975 44/18639 0.0681818181818182 0.643463751438435 0.859122950919612 0.990947764702682 GO:0003777 microtubule motor activity 5/1975 68/18639 0.0735294117647059 0.693931496649293 0.86007090190613 0.990947764702682 GO:0005342 organic acid transmembrane transporter activity 16/1975 189/18639 0.0846560846560847 0.798939119951778 0.860383635800239 0.990947764702682 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/1975 91/18639 0.0769230769230769 0.725959104186952 0.860791408431254 0.990947764702682 GO:0048306 calcium-dependent protein binding 6/1975 80/18639 0.075 0.707810126582278 0.863698308238177 0.990947764702682 GO:0005253 monoatomic anion channel activity 8/1975 103/18639 0.0776699029126214 0.733007250829544 0.866192725009121 0.990947764702682 GO:0003746 translation elongation factor activity 1/1975 18/18639 0.0555555555555556 0.524303797468354 0.866955513790327 0.990947764702682 GO:0015373 monoatomic anion:sodium symporter activity 1/1975 18/18639 0.0555555555555556 0.524303797468354 0.866955513790327 0.990947764702682 GO:0016854 racemase and epimerase activity 1/1975 18/18639 0.0555555555555556 0.524303797468354 0.866955513790327 0.990947764702682 GO:0099602 neurotransmitter receptor regulator activity 1/1975 18/18639 0.0555555555555556 0.524303797468354 0.866955513790327 0.990947764702682 GO:0008378 galactosyltransferase activity 2/1975 32/18639 0.0625 0.589841772151899 0.867183123511819 0.990947764702682 GO:0022884 macromolecule transmembrane transporter activity 2/1975 32/18639 0.0625 0.589841772151899 0.867183123511819 0.990947764702682 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1975 32/18639 0.0625 0.589841772151899 0.867183123511819 0.990947764702682 GO:0043425 bHLH transcription factor binding 2/1975 32/18639 0.0625 0.589841772151899 0.867183123511819 0.990947764702682 GO:0047498 calcium-dependent phospholipase A2 activity 2/1975 32/18639 0.0625 0.589841772151899 0.867183123511819 0.990947764702682 GO:0160041 neuropeptide activity 2/1975 32/18639 0.0625 0.589841772151899 0.867183123511819 0.990947764702682 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1975 70/18639 0.0714285714285714 0.674104882459313 0.876404968696931 0.996315141758192 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1975 70/18639 0.0714285714285714 0.674104882459313 0.876404968696931 0.996315141758192 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1975 33/18639 0.0606060606060606 0.571967779056387 0.878337843730333 0.996315141758192 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0008301 DNA binding, bending 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0016918 retinal binding 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0046624 sphingolipid transporter activity 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0070003 threonine-type peptidase activity 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0097001 ceramide binding 1/1975 19/18639 0.0526315789473684 0.496708860759494 0.881066617397228 0.996315141758192 GO:0008201 heparin binding 14/1975 172/18639 0.0813953488372093 0.768166028848984 0.883335940093724 0.997935394443004 GO:0004867 serine-type endopeptidase inhibitor activity 7/1975 95/18639 0.0736842105263158 0.695392405063291 0.888219632300965 0.999387433275356 GO:0030332 cyclin binding 2/1975 34/18639 0.0588235294117647 0.555145197319434 0.888621326252805 0.999387433275356 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/1975 34/18639 0.0588235294117647 0.555145197319434 0.888621326252805 0.999387433275356 GO:0090482 vitamin transmembrane transporter activity 2/1975 34/18639 0.0588235294117647 0.555145197319434 0.888621326252805 0.999387433275356 GO:0008237 metallopeptidase activity 15/1975 184/18639 0.0815217391304348 0.769358833241607 0.888809779300211 0.999387433275356 GO:0005326 neurotransmitter transmembrane transporter activity 1/1975 20/18639 0.05 0.471873417721519 0.893681731824751 1 GO:0016887 ATP hydrolysis activity 37/1975 417/18639 0.0887290167865707 0.837377288042983 0.894184284343586 1 GO:0016229 steroid dehydrogenase activity 2/1975 35/18639 0.0571428571428571 0.53928390596745 0.898092853073826 1 GO:0003678 DNA helicase activity 5/1975 74/18639 0.0675675675675676 0.637666780704755 0.904241180466427 1 GO:0050660 flavin adenine dinucleotide binding 6/1975 86/18639 0.0697674418604651 0.658428024727701 0.904380783062079 1 GO:0001846 opsonin binding 1/1975 21/18639 0.0476190476190476 0.449403254972875 0.904959382592575 1 GO:0008373 sialyltransferase activity 1/1975 21/18639 0.0476190476190476 0.449403254972875 0.904959382592575 1 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1975 21/18639 0.0476190476190476 0.449403254972875 0.904959382592575 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/1975 122/18639 0.0737704918032787 0.696206681884208 0.910154806211513 1 GO:0022829 wide pore channel activity 2/1975 37/18639 0.0540540540540541 0.510133424563804 0.914823218653764 1 GO:0005125 cytokine activity 19/1975 234/18639 0.0811965811965812 0.766290165530672 0.914984927049424 1 GO:0005243 gap junction channel activity 1/1975 22/18639 0.0454545454545455 0.42897583429229 0.915041304355367 1 GO:0008970 phospholipase A1 activity 1/1975 22/18639 0.0454545454545455 0.42897583429229 0.915041304355367 1 GO:0015377 chloride:monoatomic cation symporter activity 1/1975 22/18639 0.0454545454545455 0.42897583429229 0.915041304355367 1 GO:0033691 sialic acid binding 1/1975 22/18639 0.0454545454545455 0.42897583429229 0.915041304355367 1 GO:0015297 antiporter activity 10/1975 135/18639 0.0740740740740741 0.699071729957806 0.917194491675666 1 GO:0016779 nucleotidyltransferase activity 10/1975 136/18639 0.0735294117647059 0.693931496649293 0.921325475360543 1 GO:0042887 amide transmembrane transporter activity 2/1975 38/18639 0.0526315789473684 0.496708860759494 0.922186486346128 1 GO:0005212 structural constituent of eye lens 1/1975 23/18639 0.0434782608695652 0.41032471106219 0.924054218568084 1 GO:0005283 amino acid:sodium symporter activity 1/1975 23/18639 0.0434782608695652 0.41032471106219 0.924054218568084 1 GO:0043274 phospholipase binding 1/1975 23/18639 0.0434782608695652 0.41032471106219 0.924054218568084 1 GO:0140103 catalytic activity, acting on a glycoprotein 1/1975 23/18639 0.0434782608695652 0.41032471106219 0.924054218568084 1 GO:0008146 sulfotransferase activity 3/1975 53/18639 0.0566037735849057 0.534196321948889 0.929902260426024 1 GO:0015295 solute:proton symporter activity 1/1975 24/18639 0.0416666666666667 0.393227848101266 0.932111423033492 1 GO:0004177 aminopeptidase activity 2/1975 40/18639 0.05 0.471873417721519 0.935148725253672 1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/1975 40/18639 0.05 0.471873417721519 0.935148725253672 1 GO:0000049 tRNA binding 5/1975 80/18639 0.0625 0.589841772151899 0.935727657305082 1 GO:0046906 tetrapyrrole binding 11/1975 152/18639 0.0723684210526316 0.682974683544304 0.937628222571041 1 GO:0001848 complement binding 1/1975 25/18639 0.04 0.377498734177215 0.939314213230046 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1975 25/18639 0.04 0.377498734177215 0.939314213230046 1 GO:0017171 serine hydrolase activity 15/1975 198/18639 0.0757575757575758 0.714959723820483 0.939472387154633 1 GO:0001664 G protein-coupled receptor binding 24/1975 297/18639 0.0808080808080808 0.762623705408516 0.939609198761436 1 GO:0008374 O-acyltransferase activity 3/1975 55/18639 0.0545454545454545 0.514771001150748 0.940337265139582 1 GO:0008227 G protein-coupled amine receptor activity 2/1975 41/18639 0.0487804878048781 0.460364309972214 0.940835050727825 1 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/1975 41/18639 0.0487804878048781 0.460364309972214 0.940835050727825 1 GO:0020037 heme binding 10/1975 142/18639 0.0704225352112676 0.664610447495097 0.94258799442257 1 GO:0030170 pyridoxal phosphate binding 3/1975 56/18639 0.0535714285714286 0.505578661844485 0.944997088945778 1 GO:0170055 lipid transmembrane transporter activity 3/1975 56/18639 0.0535714285714286 0.505578661844485 0.944997088945778 1 GO:0004435 phosphatidylinositol phospholipase C activity 1/1975 26/18639 0.0384615384615385 0.362979552093476 0.945753153214502 1 GO:0005227 calcium-activated cation channel activity 1/1975 26/18639 0.0384615384615385 0.362979552093476 0.945753153214502 1 GO:0030247 polysaccharide binding 1/1975 26/18639 0.0384615384615385 0.362979552093476 0.945753153214502 1 GO:0050750 low-density lipoprotein particle receptor binding 1/1975 26/18639 0.0384615384615385 0.362979552093476 0.945753153214502 1 GO:0051139 metal cation:proton antiporter activity 1/1975 26/18639 0.0384615384615385 0.362979552093476 0.945753153214502 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 9/1975 132/18639 0.0681818181818182 0.643463751438435 0.947888596547364 1 GO:0070279 vitamin B6 binding 3/1975 57/18639 0.0526315789473684 0.496708860759494 0.949316690753986 1 GO:0005245 voltage-gated calcium channel activity 2/1975 43/18639 0.0465116279069767 0.438952016485134 0.950816206002914 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 13/1975 181/18639 0.0718232044198895 0.677829218826491 0.953914840964125 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1975 44/18639 0.0454545454545455 0.42897583429229 0.955182551483072 1 GO:0051959 dynein light intermediate chain binding 1/1975 28/18639 0.0357142857142857 0.337052441229656 0.956654779725274 1 GO:0008236 serine-type peptidase activity 14/1975 194/18639 0.0721649484536082 0.681054417330027 0.957231360631111 1 GO:0004175 endopeptidase activity 33/1975 405/18639 0.0814814814814815 0.768978902953587 0.959469441570204 1 GO:0003684 damaged DNA binding 4/1975 74/18639 0.0540540540540541 0.510133424563804 0.961145783530812 1 GO:0004629 phospholipase C activity 1/1975 29/18639 0.0344827586206897 0.32542994325622 0.961254576084555 1 GO:0005416 amino acid:monoatomic cation symporter activity 1/1975 29/18639 0.0344827586206897 0.32542994325622 0.961254576084555 1 GO:0005539 glycosaminoglycan binding 18/1975 242/18639 0.0743801652892562 0.701960456114656 0.962015334205347 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1975 46/18639 0.0434782608695652 0.41032471106219 0.962827562741626 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/1975 46/18639 0.0434782608695652 0.41032471106219 0.962827562741626 1 GO:0019842 vitamin binding 10/1975 150/18639 0.0666666666666667 0.629164556962025 0.963037641027058 1 GO:0140101 catalytic activity, acting on a tRNA 9/1975 139/18639 0.0647482014388489 0.61105910208542 0.965201846450409 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1975 30/18639 0.0333333333333333 0.314582278481013 0.965366462824641 1 GO:0022839 monoatomic ion-gated channel activity 1/1975 30/18639 0.0333333333333333 0.314582278481013 0.965366462824641 1 GO:0008094 ATP-dependent activity, acting on DNA 15/1975 210/18639 0.0714285714285714 0.674104882459313 0.965711164143971 1 GO:0099095 ligand-gated monoatomic anion channel activity 2/1975 47/18639 0.0425531914893617 0.401594398060867 0.966163826977998 1 GO:0140359 ABC-type transporter activity 2/1975 47/18639 0.0425531914893617 0.401594398060867 0.966163826977998 1 GO:0005452 solute:inorganic anion antiporter activity 1/1975 31/18639 0.032258064516129 0.304434463046141 0.969042170058847 1 GO:0008188 neuropeptide receptor activity 2/1975 48/18639 0.0416666666666667 0.393227848101266 0.969210874610898 1 GO:0005506 iron ion binding 10/1975 154/18639 0.0649350649350649 0.612822620417557 0.970582972146708 1 GO:0004536 DNA nuclease activity 3/1975 64/18639 0.046875 0.442381329113924 0.971752091423294 1 GO:0015106 bicarbonate transmembrane transporter activity 1/1975 32/18639 0.03125 0.294920886075949 0.972327945753912 1 GO:0042923 neuropeptide binding 1/1975 33/18639 0.0303030303030303 0.285983889528193 0.975265136442149 1 GO:0005272 sodium channel activity 2/1975 51/18639 0.0392156862745098 0.370096798212956 0.976845811988795 1 GO:0008175 tRNA methyltransferase activity 1/1975 34/18639 0.0294117647058824 0.277572598659717 0.977890706447887 1 GO:0019825 oxygen binding 1/1975 34/18639 0.0294117647058824 0.277572598659717 0.977890706447887 1 GO:0051427 hormone receptor binding 1/1975 34/18639 0.0294117647058824 0.277572598659717 0.977890706447887 1 GO:0015085 calcium ion transmembrane transporter activity 9/1975 147/18639 0.0612244897959184 0.577804184965125 0.978513319388059 1 GO:0004620 phospholipase activity 6/1975 109/18639 0.055045871559633 0.519493670886076 0.978948194830422 1 GO:0005343 organic acid:sodium symporter activity 1/1975 35/18639 0.0285714285714286 0.269641952983725 0.980237702135359 1 GO:0005254 chloride channel activity 4/1975 83/18639 0.0481927710843374 0.454817752020741 0.980777043706438 1 GO:0008509 monoatomic anion transmembrane transporter activity 9/1975 149/18639 0.0604026845637584 0.57004842409311 0.98101446460721 1 GO:0004033 aldo-keto reductase (NADPH) activity 1/1975 36/18639 0.0277777777777778 0.262151898734177 0.982335666996823 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1975 36/18639 0.0277777777777778 0.262151898734177 0.982335666996823 1 GO:0003735 structural constituent of ribosome 11/1975 175/18639 0.0628571428571429 0.593212296564195 0.982382086009718 1 GO:0004252 serine-type endopeptidase activity 11/1975 176/18639 0.0625 0.589841772151899 0.983385219264404 1 GO:0030280 structural constituent of skin epidermis 1/1975 37/18639 0.027027027027027 0.255066712281902 0.98421101278413 1 GO:0048029 monosaccharide binding 3/1975 74/18639 0.0405405405405405 0.382600068422853 0.988122756454574 1 GO:0005262 calcium channel activity 7/1975 131/18639 0.0534351145038168 0.504292202145135 0.988612593116015 1 GO:0015144 carbohydrate transmembrane transporter activity 1/1975 40/18639 0.025 0.23593670886076 0.988725203214037 1 GO:0071855 neuropeptide receptor binding 1/1975 40/18639 0.025 0.23593670886076 0.988725203214037 1 GO:0004812 aminoacyl-tRNA ligase activity 1/1975 41/18639 0.024390243902439 0.230182154986107 0.989922457026192 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/1975 41/18639 0.024390243902439 0.230182154986107 0.989922457026192 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1975 41/18639 0.024390243902439 0.230182154986107 0.989922457026192 1 GO:0140828 metal cation:monoatomic cation antiporter activity 1/1975 41/18639 0.024390243902439 0.230182154986107 0.989922457026192 1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/1975 60/18639 0.0333333333333333 0.314582278481013 0.990296408487435 1 GO:0004520 DNA endonuclease activity 1/1975 42/18639 0.0238095238095238 0.224701627486438 0.990992633785697 1 GO:0005249 voltage-gated potassium channel activity 4/1975 98/18639 0.0408163265306122 0.38520278997675 0.994402776978286 1 GO:0140375 immune receptor activity 8/1975 156/18639 0.0512820512820513 0.483972736124635 0.994953096054827 1 GO:0038187 pattern recognition receptor activity 1/1975 48/18639 0.0208333333333333 0.196613924050633 0.995408035608653 1 GO:0016298 lipase activity 6/1975 130/18639 0.0461538461538462 0.435575462512171 0.995515372472155 1 GO:0003730 mRNA 3'-UTR binding 16/1975 262/18639 0.0610687022900763 0.576333945308726 0.995964802087199 1 GO:0015291 secondary active transmembrane transporter activity 18/1975 287/18639 0.0627177700348432 0.591896969964275 0.996075369078196 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/1975 52/18639 0.0192307692307692 0.181489776046738 0.997069938202328 1 GO:0015108 chloride transmembrane transporter activity 5/1975 121/18639 0.0413223140495868 0.389978031174809 0.997109963081356 1 GO:0005267 potassium channel activity 5/1975 124/18639 0.0403225806451613 0.380543078807677 0.997741117767216 1 GO:0140097 catalytic activity, acting on DNA 21/1975 336/18639 0.0625 0.589841772151899 0.998022711586681 1 GO:0005244 voltage-gated monoatomic ion channel activity 8/1975 173/18639 0.046242774566474 0.436414721592156 0.998522973950427 1 GO:0030246 carbohydrate binding 16/1975 280/18639 0.0571428571428571 0.53928390596745 0.998606552419441 1 GO:0022832 voltage-gated channel activity 8/1975 175/18639 0.0457142857142857 0.43142712477396 0.998727215208452 1 GO:0005179 hormone activity 5/1975 132/18639 0.0378787878787879 0.357479861910242 0.998840518864692 1 GO:0015103 inorganic anion transmembrane transporter activity 7/1975 165/18639 0.0424242424242424 0.400377445339471 0.999088726324028 1 GO:0005507 copper ion binding 1/1975 63/18639 0.0158730158730159 0.149801084990958 0.999148738892305 1 GO:1901682 sulfur compound transmembrane transporter activity 1/1975 63/18639 0.0158730158730159 0.149801084990958 0.999148738892305 1 GO:0016874 ligase activity 7/1975 167/18639 0.0419161676646707 0.395582505874327 0.999220933626437 1 GO:0008528 G protein-coupled peptide receptor activity 4/1975 122/18639 0.0327868852459016 0.309425191948537 0.999309779240153 1 GO:0004497 monooxygenase activity 3/1975 106/18639 0.0283018867924528 0.267098160974445 0.999375190994329 1 GO:0022843 voltage-gated monoatomic cation channel activity 5/1975 143/18639 0.034965034965035 0.329981410994069 0.999546237964748 1 GO:0003823 antigen binding 7/1975 174/18639 0.0402298850574713 0.379668267132257 0.999552630826104 1 GO:0015079 potassium ion transmembrane transporter activity 6/1975 160/18639 0.0375 0.353905063291139 0.999593760290846 1 GO:0001653 peptide receptor activity 4/1975 128/18639 0.03125 0.294920886075949 0.999598215129803 1 GO:0015293 symporter activity 5/1975 146/18639 0.0342465753424658 0.323200971042136 0.999650030854625 1 GO:0015294 solute:monoatomic cation symporter activity 3/1975 116/18639 0.0258620689655172 0.244072457442165 0.999760432942763 1 GO:0015370 solute:sodium symporter activity 1/1975 79/18639 0.0126582278481013 0.119461624739625 0.999859187379515 1 GO:0046873 metal ion transmembrane transporter activity 26/1975 450/18639 0.0577777777777778 0.545275949367089 0.999896495578072 1 GO:0099094 ligand-gated monoatomic cation channel activity 3/1975 136/18639 0.0220588235294118 0.208179448994788 0.999966116522321 1 GO:0005261 monoatomic cation channel activity 16/1975 341/18639 0.0469208211143695 0.442813764430751 0.999974665178148 1 GO:0005216 monoatomic ion channel activity 24/1975 448/18639 0.0535714285714286 0.505578661844485 0.99997504588867 1 GO:0015081 sodium ion transmembrane transporter activity 4/1975 164/18639 0.024390243902439 0.230182154986107 0.999986005623132 1 GO:0015276 ligand-gated monoatomic ion channel activity 4/1975 186/18639 0.021505376344086 0.202956308697428 0.9999983275876 1 GO:0022834 ligand-gated channel activity 4/1975 188/18639 0.0212765957446809 0.200797199030434 0.999998624322882 1 GO:0022836 gated channel activity 11/1975 318/18639 0.0345911949685535 0.326453307857655 0.999999458178845 1 GO:0045182 translation regulator activity 11/1975 356/18639 0.0308988764044944 0.291607168254871 0.999999978103723 1 GO:0030371 translation repressor activity 9/1975 329/18639 0.027355623100304 0.258167827324843 0.99999998770844 1 GO:0004984 olfactory receptor activity 1/1975 419/18639 0.00238663484486874 0.0225237908220295 1 1