ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	126/2525	489/18639	0.257668711656442	1.90205430358987	2.21773581137624e-13	1.67721368533059e-10
GO:0060589	nucleoside-triphosphatase regulator activity	126/2525	490/18639	0.257142857142857	1.89817256011315	2.59630601444365e-13	1.67721368533059e-10
GO:0005096	GTPase activator activity	73/2525	271/18639	0.269372693726937	1.98845054985203	3.27696094803884e-09	1.41127784828873e-06
GO:0031267	small GTPase binding	73/2525	283/18639	0.257950530035336	1.90413462547668	2.38794568726975e-08	7.71306456988129e-06
GO:0051020	GTPase binding	77/2525	315/18639	0.244444444444444	1.80443564356436	1.1570072016215e-07	2.98970660898997e-05
GO:0005085	guanyl-nucleotide exchange factor activity	59/2525	230/18639	0.256521739130435	1.89358760223848	6.24084753352323e-07	0.000134386250221867
GO:0023023	MHC protein complex binding	17/2525	37/18639	0.459459459459459	3.39162964945143	1.7626183096405e-06	0.000325328979436504
GO:0023026	MHC class II protein complex binding	14/2525	27/18639	0.518518518518518	3.82759075907591	2.38945995172879e-06	0.0003858977822042
GO:0003725	double-stranded RNA binding	24/2525	75/18639	0.32	2.3621702970297	3.12609210776585e-05	0.00426928548713055
GO:0044389	ubiquitin-like protein ligase binding	70/2525	322/18639	0.217391304347826	1.60473525613431	3.30440053183479e-05	0.00426928548713055
GO:0140375	immune receptor activity	40/2525	156/18639	0.256410256410256	1.89276466108149	3.82223394876615e-05	0.0044893875107326
GO:0106310	protein serine kinase activity	75/2525	361/18639	0.207756232686981	1.53361125586243	8.59460699651771e-05	0.00925352686625073
GO:0042625	ATPase-coupled ion transmembrane transporter activity	11/2525	24/18639	0.458333333333333	3.38331683168317	0.000125469108842577	0.010807072574974
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	11/2525	24/18639	0.458333333333333	3.38331683168317	0.000125469108842577	0.010807072574974
GO:0046961	proton-transporting ATPase activity, rotational mechanism	11/2525	24/18639	0.458333333333333	3.38331683168317	0.000125469108842577	0.010807072574974
GO:0031625	ubiquitin protein ligase binding	64/2525	302/18639	0.211920529801325	1.5643511900859	0.000152831677010978	0.0123411579186365
GO:0004674	protein serine/threonine kinase activity	85/2525	433/18639	0.196304849884527	1.44907964237532	0.000232497132716926	0.0176697820864864
GO:0005543	phospholipid binding	95/2525	497/18639	0.191146881287726	1.41100464171166	0.000275822254374199	0.0189447071213172
GO:0019208	phosphatase regulator activity	30/2525	117/18639	0.256410256410256	1.89276466108149	0.000337628665894383	0.0189447071213172
GO:0001618	virus receptor activity	23/2525	81/18639	0.283950617283951	2.09606160616062	0.000338705804361067	0.0189447071213172
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	7/2525	12/18639	0.583333333333333	4.3060396039604	0.000351914064173075	0.0189447071213172
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	7/2525	12/18639	0.583333333333333	4.3060396039604	0.000351914064173075	0.0189447071213172
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	7/2525	12/18639	0.583333333333333	4.3060396039604	0.000351914064173075	0.0189447071213172
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	7/2525	12/18639	0.583333333333333	4.3060396039604	0.000351914064173075	0.0189447071213172
GO:0140272	exogenous protein binding	23/2525	82/18639	0.280487804878049	2.07049987925622	0.00041122567702663	0.0207236233645019
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	10/2525	23/18639	0.434782608695652	3.20947051226862	0.000433078816440829	0.0207236233645019
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/2525	23/18639	0.434782608695652	3.20947051226862	0.000433078816440829	0.0207236233645019
GO:0016779	nucleotidyltransferase activity	33/2525	136/18639	0.242647058823529	1.7911677344205	0.000518730285086488	0.0239356974404194
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	7/2525	13/18639	0.538461538461538	3.97480578827113	0.000673299618712867	0.0292278004573898
GO:0140313	molecular sequestering activity	17/2525	55/18639	0.309090909090909	2.28164176417642	0.000678664097307813	0.0292278004573898
GO:0035091	phosphatidylinositol binding	58/2525	284/18639	0.204225352112676	1.50754706456561	0.000801653114311051	0.0334108330222541
GO:0140311	protein sequestering activity	12/2525	33/18639	0.363636363636364	2.68428442844284	0.000833563422825254	0.0336551231965696
GO:1990226	histone methyltransferase binding	8/2525	17/18639	0.470588235294118	3.47377984857309	0.000870987139521739	0.0341004661897602
GO:0017025	TBP-class protein binding	10/2525	25/18639	0.4	2.95271287128713	0.000956856905335055	0.0363605624027321
GO:0005126	cytokine receptor binding	56/2525	275/18639	0.203636363636364	1.50319927992799	0.00104767165779953	0.0386740509107713
GO:0038187	pattern recognition receptor activity	15/2525	48/18639	0.3125	2.30680693069307	0.0012171947704641	0.0436837678733226
GO:0140296	general transcription initiation factor binding	16/2525	53/18639	0.30188679245283	2.22846254436764	0.00128106133055384	0.0447332767317721
GO:0035173	histone kinase activity	69/2525	360/18639	0.191666666666667	1.41484158415842	0.00164367922064622	0.055265133846581
GO:0141003	histone H2AX kinase activity	68/2525	354/18639	0.192090395480226	1.41796945796275	0.00166821998453302	0.055265133846581
GO:0005164	tumor necrosis factor receptor binding	11/2525	31/18639	0.354838709677419	2.61934206323858	0.00171802038030144	0.0554920582837365
GO:0004715	non-membrane spanning protein tyrosine kinase activity	14/2525	45/18639	0.311111111111111	2.29655445544554	0.00183883374425465	0.0565660285137382
GO:0008009	chemokine activity	14/2525	45/18639	0.311111111111111	2.29655445544554	0.00183883374425465	0.0565660285137382
GO:0140857	histone H3T45 kinase activity	50/2525	246/18639	0.203252032520325	1.50036223134509	0.00196033357951768	0.0589011856915544
GO:0140996	histone H3 kinase activity	68/2525	357/18639	0.19047619047619	1.40605374823197	0.00207859574316037	0.0603879439446154
GO:0043178	alcohol binding	23/2525	92/18639	0.25	1.84544554455446	0.00226586788064285	0.0603879439446154
GO:0004679	AMP-activated protein kinase activity	50/2525	248/18639	0.201612903225806	1.48826253593101	0.00233709744485758	0.0603879439446154
GO:0004875	complement receptor activity	6/2525	12/18639	0.5	3.69089108910891	0.00272843201749293	0.0603879439446154
GO:0035497	cAMP response element binding	6/2525	12/18639	0.5	3.69089108910891	0.00272843201749293	0.0603879439446154
GO:0004676	3-phosphoinositide-dependent protein kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0004711	ribosomal protein S6 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0035175	histone H3S10 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0035979	histone H2AXS139 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0044022	histone H3S28 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0044023	histone H4S1 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0044024	histone H2AS1 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0044025	histone H2BS14 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0072354	histone H3T3 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0072371	histone H2AS121 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0072518	Rho-dependent protein serine/threonine kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0140823	histone H2BS36 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0140855	histone H3S57 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0140995	histone H2A kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0140997	histone H4 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0140998	histone H2B kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:1990244	histone H2AT120 kinase activity	49/2525	245/18639	0.2	1.47635643564356	0.00303809315510836	0.0603879439446154
GO:0004677	DNA-dependent protein kinase activity	49/2525	246/18639	0.199186991869919	1.47035498671818	0.00330616533380858	0.0647206910800105
GO:0035402	histone H3T11 kinase activity	49/2525	247/18639	0.198380566801619	1.46440213252094	0.00359438944344719	0.0680411449608129
GO:0035403	histone H3T6 kinase activity	49/2525	247/18639	0.198380566801619	1.46440213252094	0.00359438944344719	0.0680411449608129
GO:0046332	SMAD binding	20/2525	79/18639	0.253164556962025	1.86880561473869	0.00363377631756663	0.0680411449608129
GO:0019211	phosphatase activator activity	9/2525	25/18639	0.36	2.65744158415842	0.00399678358517657	0.0737692056006875
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	48/2525	243/18639	0.197530864197531	1.4581298129813	0.00427487858681618	0.074372391065108
GO:0015485	cholesterol binding	15/2525	54/18639	0.277777777777778	2.05049504950495	0.00437819723136523	0.074372391065108
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	15/2525	54/18639	0.277777777777778	2.05049504950495	0.00437819723136523	0.074372391065108
GO:0001222	transcription corepressor binding	14/2525	49/18639	0.285714285714286	2.10908062234795	0.00440987888876204	0.074372391065108
GO:0016763	pentosyltransferase activity	14/2525	49/18639	0.285714285714286	2.10908062234795	0.00440987888876204	0.074372391065108
GO:0072542	protein phosphatase activator activity	8/2525	21/18639	0.380952380952381	2.81210749646393	0.0044169447009805	0.074372391065108
GO:0005035	death receptor activity	6/2525	13/18639	0.461538461538462	3.40697638994669	0.00448997407359011	0.074372391065108
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	6/2525	13/18639	0.461538461538462	3.40697638994669	0.00448997407359011	0.074372391065108
GO:0019207	kinase regulator activity	55/2525	287/18639	0.191637630662021	1.4146272466968	0.00458841800878083	0.0750409628777826
GO:0031072	heat shock protein binding	29/2525	131/18639	0.221374045801527	1.63413498601769	0.00470308362607269	0.0759548005610739
GO:1901981	phosphatidylinositol phosphate binding	38/2525	185/18639	0.205405405405405	1.51625796093123	0.00529814298668914	0.0845086510963255
GO:0042605	peptide antigen binding	13/2525	45/18639	0.288888888888889	2.13251485148515	0.00539120996529759	0.0849444301849327
GO:0033691	sialic acid binding	8/2525	22/18639	0.363636363636364	2.68428442844284	0.00612796908001112	0.0953895909804141
GO:0008239	dipeptidyl-peptidase activity	5/2525	10/18639	0.5	3.69089108910891	0.00633127438655184	0.096235370675588
GO:0032395	MHC class II receptor activity	5/2525	10/18639	0.5	3.69089108910891	0.00633127438655184	0.096235370675588
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	12/2525	41/18639	0.292682926829268	2.16052161313692	0.00658480708043793	0.0989252412549512
GO:0004706	JUN kinase kinase kinase activity	7/2525	18/18639	0.388888888888889	2.87069306930693	0.00673663525626004	0.100042905184919
GO:0032934	sterol binding	17/2525	68/18639	0.25	1.84544554455446	0.00800146703785628	0.117118826744519
GO:0019888	protein phosphatase regulator activity	24/2525	107/18639	0.224299065420561	1.65572684371241	0.00806778295685928	0.117118826744519
GO:0061659	ubiquitin-like protein ligase activity	67/2525	372/18639	0.18010752688172	1.32951453209837	0.00851267158707226	0.122204129894415
GO:0045499	chemorepellent activity	9/2525	28/18639	0.321428571428571	2.37271570014144	0.00926404541105763	0.131529084297653
GO:0050145	nucleoside monophosphate kinase activity	7/2525	19/18639	0.368421052631579	2.71960396039604	0.00943750345065281	0.132535374546124
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	10/2525	33/18639	0.303030303030303	2.23690369036904	0.0097730434600552	0.135771743552595
GO:0050700	CARD domain binding	6/2525	15/18639	0.4	2.95271287128713	0.0102951533685339	0.137509542504972
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	5/2525	11/18639	0.454545454545455	3.35535553555355	0.0103238588413175	0.137509542504972
GO:0042608	T cell receptor binding	5/2525	11/18639	0.454545454545455	3.35535553555355	0.0103238588413175	0.137509542504972
GO:0140031	phosphorylation-dependent protein binding	5/2525	11/18639	0.454545454545455	3.35535553555355	0.0103238588413175	0.137509542504972
GO:0030246	carbohydrate binding	52/2525	280/18639	0.185714285714286	1.37090240452617	0.0106028062446329	0.138595969407027
GO:0004540	RNA nuclease activity	26/2525	121/18639	0.214876033057851	1.58616807135259	0.0106199697920245	0.138595969407027
GO:0003924	GTPase activity	60/2525	331/18639	0.181268882175227	1.33808740390655	0.0107372722994519	0.138725558108918
GO:0030215	semaphorin receptor binding	8/2525	24/18639	0.333333333333333	2.46059405940594	0.0109960788927458	0.14066271217255
GO:0140297	DNA-binding transcription factor binding	84/2525	488/18639	0.172131147540984	1.27063463723422	0.0115890923053602	0.14679516920123
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	9/2525	29/18639	0.310344827586207	2.29089791737794	0.011851082829837	0.148656301127664
GO:0016505	peptidase activator activity involved in apoptotic process	7/2525	20/18639	0.35	2.58362376237624	0.0128511125296255	0.159650359502655
GO:0032813	tumor necrosis factor receptor superfamily binding	13/2525	50/18639	0.26	1.91926336633663	0.013732357256867	0.165628672266146
GO:0001540	amyloid-beta binding	19/2525	83/18639	0.228915662650602	1.68980555886914	0.0138619065190868	0.165628672266146
GO:0140098	catalytic activity, acting on RNA	68/2525	387/18639	0.175710594315245	1.29705733364034	0.0139221192939243	0.165628672266146
GO:0019787	ubiquitin-like protein transferase activity	82/2525	479/18639	0.171189979123173	1.26368713698092	0.0142364038374908	0.165628672266146
GO:0004709	MAP kinase kinase kinase activity	8/2525	25/18639	0.32	2.3621702970297	0.0142898649198372	0.165628672266146
GO:0022853	active monoatomic ion transmembrane transporter activity	25/2525	118/18639	0.211864406779661	1.56393690216479	0.0143529945482631	0.165628672266146
GO:0016798	hydrolase activity, acting on glycosyl bonds	27/2525	130/18639	0.207692307692308	1.53313937547601	0.0145760042822962	0.165628672266146
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	27/2525	130/18639	0.207692307692308	1.53313937547601	0.0145760042822962	0.165628672266146
GO:0015923	mannosidase activity	6/2525	16/18639	0.375	2.76816831683168	0.0146142946117188	0.165628672266146
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	6/2525	16/18639	0.375	2.76816831683168	0.0146142946117188	0.165628672266146
GO:0031624	ubiquitin conjugating enzyme binding	9/2525	30/18639	0.3	2.21453465346535	0.0149406599294946	0.167855066338322
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	16/2525	67/18639	0.238805970149254	1.76281365449978	0.0154041359065945	0.169565996003313
GO:0005095	GTPase inhibitor activity	5/2525	12/18639	0.416666666666667	3.07574257425743	0.015749163715478	0.169565996003313
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/2525	12/18639	0.416666666666667	3.07574257425743	0.015749163715478	0.169565996003313
GO:0070008	serine-type exopeptidase activity	5/2525	12/18639	0.416666666666667	3.07574257425743	0.015749163715478	0.169565996003313
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/2525	12/18639	0.416666666666667	3.07574257425743	0.015749163715478	0.169565996003313
GO:0019887	protein kinase regulator activity	47/2525	255/18639	0.184313725490196	1.36056377402446	0.016538868854792	0.176596847606539
GO:0042277	peptide binding	46/2525	249/18639	0.184738955823293	1.36370273171895	0.016910581680348	0.17908583222139
GO:0016504	peptidase activator activity	14/2525	57/18639	0.245614035087719	1.81306930693069	0.0177856273491564	0.18682138646431
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	20/2525	91/18639	0.21978021978022	1.62236970949842	0.0182362980439786	0.188477426334199
GO:0070412	R-SMAD binding	8/2525	26/18639	0.307692307692308	2.27131759329779	0.0182459727537026	0.188477426334199
GO:0005484	SNAP receptor activity	10/2525	36/18639	0.277777777777778	2.05049504950495	0.0183809254784126	0.188477426334199
GO:0017124	SH3 domain binding	24/2525	115/18639	0.208695652173913	1.54054584588894	0.0193042262208775	0.196386301396644
GO:0038191	neuropilin binding	6/2525	17/18639	0.352941176470588	2.60533488642982	0.0200469082873007	0.202348480524942
GO:0061133	endopeptidase activator activity	7/2525	22/18639	0.318181818181818	2.34874887488749	0.0221736358804517	0.22208013610499
GO:0004518	nuclease activity	39/2525	209/18639	0.186602870813397	1.37746174617462	0.0225636108243777	0.224247578346892
GO:0003779	actin binding	75/2525	443/18639	0.169300225733634	1.2497373890888	0.023289757004942	0.228597263901975
GO:0035591	signaling adaptor activity	26/2525	129/18639	0.201550387596899	1.48780105917568	0.0233551384172297	0.228597263901975
GO:0008375	acetylglucosaminyltransferase activity	11/2525	43/18639	0.255813953488372	1.88836288279991	0.0252068677790389	0.242593346817767
GO:0140030	modification-dependent protein binding	33/2525	173/18639	0.190751445086705	1.40808561781034	0.0253362707256305	0.242593346817767
GO:0044325	transmembrane transporter binding	27/2525	136/18639	0.198529411764706	1.46550087361677	0.0253483760219803	0.242593346817767
GO:0000149	SNARE binding	22/2525	106/18639	0.207547169811321	1.53206799925276	0.0257794909931046	0.244905164434494
GO:0001098	basal transcription machinery binding	14/2525	60/18639	0.233333333333333	1.72241584158416	0.0272375450767991	0.255006581443655
GO:0001099	basal RNA polymerase II transcription machinery binding	14/2525	60/18639	0.233333333333333	1.72241584158416	0.0272375450767991	0.255006581443655
GO:0140416	transcription regulator inhibitor activity	9/2525	33/18639	0.272727272727273	2.01321332133213	0.0277275145192018	0.257726250063372
GO:0097718	disordered domain specific binding	8/2525	28/18639	0.285714285714286	2.10908062234795	0.0283929104888894	0.262026002511751
GO:0001046	core promoter sequence-specific DNA binding	11/2525	44/18639	0.25	1.84544554455446	0.0296229340915128	0.269526977790384
GO:0019205	nucleobase-containing compound kinase activity	11/2525	44/18639	0.25	1.84544554455446	0.0296229340915128	0.269526977790384
GO:0016755	aminoacyltransferase activity	82/2525	496/18639	0.165322580645161	1.22037527946343	0.0309762319866774	0.277520665856827
GO:0004857	enzyme inhibitor activity	70/2525	416/18639	0.168269230769231	1.24212680883473	0.031075118635532	0.277520665856827
GO:0005496	steroid binding	22/2525	108/18639	0.203703703703704	1.50369636963696	0.0312923468581495	0.277520665856827
GO:0016776	phosphotransferase activity, phosphate group as acceptor	10/2525	39/18639	0.256410256410256	1.89276466108149	0.031558717430628	0.277520665856827
GO:0005161	platelet-derived growth factor receptor binding	5/2525	14/18639	0.357142857142857	2.63635077793494	0.0315754937159084	0.277520665856827
GO:0141108	transporter regulator activity	32/2525	170/18639	0.188235294117647	1.38951193942924	0.032329359681618	0.282226572355746
GO:0008175	tRNA methyltransferase activity	9/2525	34/18639	0.264705882352941	1.95400116482236	0.0333170812268767	0.287056759973563
GO:0005125	cytokine activity	42/2525	234/18639	0.179487179487179	1.32493526275704	0.033327023216745	0.287056759973563
GO:0141110	transporter inhibitor activity	11/2525	45/18639	0.244444444444444	1.80443564356436	0.034565201216324	0.290164381088805
GO:0016757	glycosyltransferase activity	47/2525	267/18639	0.176029962546816	1.29941484036044	0.0347490290431797	0.290164381088805
GO:0001091	RNA polymerase II general transcription initiation factor binding	7/2525	24/18639	0.291666666666667	2.1530198019802	0.0353462881438605	0.290164381088805
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	7/2525	24/18639	0.291666666666667	2.1530198019802	0.0353462881438605	0.290164381088805
GO:0043998	histone H2A acetyltransferase activity	7/2525	24/18639	0.291666666666667	2.1530198019802	0.0353462881438605	0.290164381088805
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	4/2525	10/18639	0.4	2.95271287128713	0.0358345888680394	0.290164381088805
GO:0005031	tumor necrosis factor receptor activity	4/2525	10/18639	0.4	2.95271287128713	0.0358345888680394	0.290164381088805
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/2525	10/18639	0.4	2.95271287128713	0.0358345888680394	0.290164381088805
GO:0043422	protein kinase B binding	4/2525	10/18639	0.4	2.95271287128713	0.0358345888680394	0.290164381088805
GO:0061630	ubiquitin protein ligase activity	60/2525	353/18639	0.169971671388102	1.25469385465459	0.0362838693281133	0.290164381088805
GO:0030145	manganese ion binding	15/2525	68/18639	0.220588235294118	1.62833430401864	0.0363828403532402	0.290164381088805
GO:1990841	promoter-specific chromatin binding	15/2525	68/18639	0.220588235294118	1.62833430401864	0.0363828403532402	0.290164381088805
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	10/2525	40/18639	0.25	1.84544554455446	0.0371392891906795	0.294380132726122
GO:0015078	proton transmembrane transporter activity	34/2525	185/18639	0.183783783783784	1.35665185978057	0.0382494686799194	0.301331180088146
GO:1990782	protein tyrosine kinase binding	23/2525	117/18639	0.196581196581197	1.45111957349581	0.0407037010990978	0.318722314060814
GO:0004559	alpha-mannosidase activity	5/2525	15/18639	0.333333333333333	2.46059405940594	0.0422156638895956	0.32465855800808
GO:0015929	hexosaminidase activity	5/2525	15/18639	0.333333333333333	2.46059405940594	0.0422156638895956	0.32465855800808
GO:0017081	chloride channel regulator activity	5/2525	15/18639	0.333333333333333	2.46059405940594	0.0422156638895956	0.32465855800808
GO:0001727	lipid kinase activity	10/2525	41/18639	0.24390243902439	1.8004346776141	0.0433663264534299	0.326871342210379
GO:0042169	SH2 domain binding	10/2525	41/18639	0.24390243902439	1.8004346776141	0.0433663264534299	0.326871342210379
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	7/2525	25/18639	0.28	2.06689900990099	0.0435348971754251	0.326871342210379
GO:0017056	structural constituent of nuclear pore	7/2525	25/18639	0.28	2.06689900990099	0.0435348971754251	0.326871342210379
GO:0001614	purinergic nucleotide receptor activity	6/2525	20/18639	0.3	2.21453465346535	0.0440213727125433	0.326871342210379
GO:0016502	nucleotide receptor activity	6/2525	20/18639	0.3	2.21453465346535	0.0440213727125433	0.326871342210379
GO:0061134	peptidase regulator activity	40/2525	226/18639	0.176991150442478	1.30651012003855	0.044844128905474	0.331077797404985
GO:0005525	GTP binding	63/2525	378/18639	0.166666666666667	1.23029702970297	0.0460778749729469	0.338253491278678
GO:0016409	palmitoyltransferase activity	9/2525	36/18639	0.25	1.84544554455446	0.0467237474053475	0.339140908133196
GO:0044390	ubiquitin-like protein conjugating enzyme binding	9/2525	36/18639	0.25	1.84544554455446	0.0467237474053475	0.339140908133196
GO:0016741	transferase activity, transferring one-carbon groups	38/2525	215/18639	0.176744186046512	1.30468708266175	0.0503617545222852	0.357870859105689
GO:0003953	NAD+ nucleosidase activity	4/2525	11/18639	0.363636363636364	2.68428442844284	0.0504121488833091	0.357870859105689
GO:0019203	carbohydrate phosphatase activity	4/2525	11/18639	0.363636363636364	2.68428442844284	0.0504121488833091	0.357870859105689
GO:0019864	IgG binding	4/2525	11/18639	0.363636363636364	2.68428442844284	0.0504121488833091	0.357870859105689
GO:0032266	phosphatidylinositol-3-phosphate binding	11/2525	48/18639	0.229166666666667	1.69165841584158	0.0528030286119128	0.366865362902675
GO:0008198	ferrous iron binding	7/2525	26/18639	0.269230769230769	1.98740289413557	0.0528518693307965	0.366865362902675
GO:0052742	phosphatidylinositol kinase activity	7/2525	26/18639	0.269230769230769	1.98740289413557	0.0528518693307965	0.366865362902675
GO:0070851	growth factor receptor binding	26/2525	139/18639	0.18705035971223	1.38076501175297	0.0530587577110412	0.366865362902675
GO:0004842	ubiquitin-protein transferase activity	73/2525	449/18639	0.162583518930958	1.20015612251648	0.0541797357853107	0.366865362902675
GO:0061135	endopeptidase regulator activity	33/2525	184/18639	0.179347826086957	1.32390658631081	0.0545124197050093	0.366865362902675
GO:0016675	oxidoreductase activity, acting on a heme group of donors	5/2525	16/18639	0.3125	2.30680693069307	0.0547617408340851	0.366865362902675
GO:0034450	ubiquitin-ubiquitin ligase activity	5/2525	16/18639	0.3125	2.30680693069307	0.0547617408340851	0.366865362902675
GO:0008238	exopeptidase activity	20/2525	102/18639	0.196078431372549	1.44740827023879	0.0547841460588475	0.366865362902675
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/2525	21/18639	0.285714285714286	2.10908062234795	0.0548026432199816	0.366865362902675
GO:0051010	microtubule plus-end binding	6/2525	21/18639	0.285714285714286	2.10908062234795	0.0548026432199816	0.366865362902675
GO:0004896	cytokine receptor activity	19/2525	96/18639	0.197916666666667	1.46097772277228	0.0554752817220022	0.36915199795036
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/2525	60/18639	0.216666666666667	1.59938613861386	0.0557156653253252	0.36915199795036
GO:0051117	ATPase binding	17/2525	84/18639	0.202380952380952	1.49393210749646	0.0564678052338273	0.369952684357864
GO:0008168	methyltransferase activity	36/2525	204/18639	0.176470588235294	1.30266744321491	0.0566077804765584	0.369952684357864
GO:0042379	chemokine receptor binding	15/2525	72/18639	0.208333333333333	1.53787128712871	0.0566955352189297	0.369952684357864
GO:0001221	transcription coregulator binding	22/2525	115/18639	0.191304347826087	1.41216702539819	0.0576314327760865	0.373771853998958
GO:0008200	ion channel inhibitor activity	10/2525	43/18639	0.232558139534884	1.7166935298181	0.0578594201236777	0.373771853998958
GO:0120015	sterol transfer activity	8/2525	32/18639	0.25	1.84544554455446	0.0590296533578264	0.37943438874782
GO:0099106	ion channel regulator activity	29/2525	160/18639	0.18125	1.33794801980198	0.0607758451932721	0.387277808741833
GO:0015026	coreceptor activity	13/2525	61/18639	0.213114754098361	1.57316669371855	0.0623856662385761	0.387277808741833
GO:0008173	RNA methyltransferase activity	14/2525	67/18639	0.208955223880597	1.54246194768731	0.0627687530526924	0.387277808741833
GO:0004521	RNA endonuclease activity	15/2525	73/18639	0.205479452054795	1.51680455716805	0.0627894408161559	0.387277808741833
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	30/2525	167/18639	0.179640718562874	1.32606865476967	0.0631338793713594	0.387277808741833
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	9/2525	38/18639	0.236842105263158	1.74831683168317	0.0632936552858798	0.387277808741833
GO:0042626	ATPase-coupled transmembrane transporter activity	19/2525	98/18639	0.193877551020408	1.43116185087897	0.0660008924979278	0.387277808741833
GO:0016248	channel inhibitor activity	10/2525	44/18639	0.227272727272727	1.67767776777678	0.0661642689566673	0.387277808741833
GO:0032931	histone H3K56 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0043992	histone H3K9 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0043993	histone H3K18 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0043994	histone H3K23 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0043999	histone H2AK5 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0044012	histone H2AK9 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0044014	histone H2BK5 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0044015	histone H2BK12 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0044016	histone H3K4 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0044017	histone H3K27 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0044018	histone H3K36 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0046972	histone H4K16 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0140908	histone H3K122 acetyltransferase activity	6/2525	22/18639	0.272727272727273	2.01321332133213	0.0670385209723052	0.387277808741833
GO:0016247	channel regulator activity	30/2525	168/18639	0.178571428571429	1.31817538896747	0.0672907546263805	0.387277808741833
GO:0008603	cAMP-dependent protein kinase regulator activity	4/2525	12/18639	0.333333333333333	2.46059405940594	0.0677436414672247	0.387277808741833
GO:0016423	tRNA (guanine) methyltransferase activity	4/2525	12/18639	0.333333333333333	2.46059405940594	0.0677436414672247	0.387277808741833
GO:0035259	nuclear glucocorticoid receptor binding	4/2525	12/18639	0.333333333333333	2.46059405940594	0.0677436414672247	0.387277808741833
GO:0004659	prenyltransferase activity	5/2525	17/18639	0.294117647058824	2.17111240535818	0.0692262543952452	0.390569085932999
GO:0008429	phosphatidylethanolamine binding	5/2525	17/18639	0.294117647058824	2.17111240535818	0.0692262543952452	0.390569085932999
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/2525	17/18639	0.294117647058824	2.17111240535818	0.0692262543952452	0.390569085932999
GO:0036408	histone H3K14 acetyltransferase activity	7/2525	28/18639	0.25	1.84544554455446	0.074969551748033	0.420933558744423
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	57/2525	349/18639	0.163323782234957	1.20562058498113	0.0752597926238094	0.420933558744423
GO:0030544	Hsp70 protein binding	11/2525	51/18639	0.215686274509804	1.59214909726267	0.0765635075425386	0.426379533383448
GO:0042171	lysophosphatidic acid acyltransferase activity	6/2525	23/18639	0.260869565217391	1.92568230736117	0.080730654099371	0.440101287326529
GO:0044013	histone H2B acetyltransferase activity	6/2525	23/18639	0.260869565217391	1.92568230736117	0.080730654099371	0.440101287326529
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/2525	23/18639	0.260869565217391	1.92568230736117	0.080730654099371	0.440101287326529
GO:0070577	lysine-acetylated histone binding	6/2525	23/18639	0.260869565217391	1.92568230736117	0.080730654099371	0.440101287326529
GO:0071617	lysophospholipid acyltransferase activity	6/2525	23/18639	0.260869565217391	1.92568230736117	0.080730654099371	0.440101287326529
GO:0004532	RNA exonuclease activity	9/2525	40/18639	0.225	1.66090099009901	0.0831713504187773	0.448289897988825
GO:0030331	nuclear estrogen receptor binding	9/2525	40/18639	0.225	1.66090099009901	0.0831713504187773	0.448289897988825
GO:0004536	DNA nuclease activity	13/2525	64/18639	0.203125	1.4994245049505	0.085492066499996	0.448289897988825
GO:0000900	mRNA regulatory element binding translation repressor activity	5/2525	18/18639	0.277777777777778	2.05049504950495	0.0855817196231006	0.448289897988825
GO:0016854	racemase and epimerase activity	5/2525	18/18639	0.277777777777778	2.05049504950495	0.0855817196231006	0.448289897988825
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/2525	18/18639	0.277777777777778	2.05049504950495	0.0855817196231006	0.448289897988825
GO:0001217	DNA-binding transcription repressor activity	46/2525	278/18639	0.165467625899281	1.22144597193532	0.0857096158041267	0.448289897988825
GO:0030159	signaling receptor complex adaptor activity	11/2525	52/18639	0.211538461538462	1.56153084539223	0.0857684995464593	0.448289897988825
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/2525	13/18639	0.307692307692308	2.27131759329779	0.0877247455674765	0.448289897988825
GO:0031994	insulin-like growth factor I binding	4/2525	13/18639	0.307692307692308	2.27131759329779	0.0877247455674765	0.448289897988825
GO:0035325	Toll-like receptor binding	4/2525	13/18639	0.307692307692308	2.27131759329779	0.0877247455674765	0.448289897988825
GO:0140852	histone ubiquitin ligase activity	4/2525	13/18639	0.307692307692308	2.27131759329779	0.0877247455674765	0.448289897988825
GO:0004519	endonuclease activity	23/2525	127/18639	0.181102362204724	1.33685818975598	0.0877310775955521	0.448289897988825
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	7/2525	29/18639	0.241379310344828	1.78180949129396	0.0877843221293906	0.448289897988825
GO:0010484	histone H3 acetyltransferase activity	7/2525	29/18639	0.241379310344828	1.78180949129396	0.0877843221293906	0.448289897988825
GO:0097472	cyclin-dependent protein kinase activity	7/2525	29/18639	0.241379310344828	1.78180949129396	0.0877843221293906	0.448289897988825
GO:0004713	protein tyrosine kinase activity	25/2525	140/18639	0.178571428571429	1.31817538896747	0.0884544061530984	0.448679928449457
GO:0015399	primary active transmembrane transporter activity	29/2525	166/18639	0.174698795180723	1.28958845282119	0.0885552490360771	0.448679928449457
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	16/2525	83/18639	0.192771084337349	1.42299415483717	0.0898281672760299	0.453351531721214
GO:0000175	3'-5'-RNA exonuclease activity	8/2525	35/18639	0.228571428571429	1.68726449787836	0.0920108924528842	0.458701995189731
GO:0010485	histone H4 acetyltransferase activity	8/2525	35/18639	0.228571428571429	1.68726449787836	0.0920108924528842	0.458701995189731
GO:0035401	histone H3Y41 kinase activity	21/2525	115/18639	0.182608695652174	1.34797761515282	0.0928054104780848	0.458701995189731
GO:0140801	histone H2AXY142 kinase activity	21/2525	115/18639	0.182608695652174	1.34797761515282	0.0928054104780848	0.458701995189731
GO:0001530	lipopolysaccharide binding	9/2525	41/18639	0.219512195121951	1.62039120985269	0.0943665134090312	0.458701995189731
GO:0017080	sodium channel regulator activity	9/2525	41/18639	0.219512195121951	1.62039120985269	0.0943665134090312	0.458701995189731
GO:0061733	protein-lysine-acetyltransferase activity	10/2525	47/18639	0.212765957446809	1.5705919528123	0.0954430946672814	0.458701995189731
GO:0019210	kinase inhibitor activity	17/2525	90/18639	0.188888888888889	1.39433663366337	0.0954827263904028	0.458701995189731
GO:0005246	calcium channel regulator activity	11/2525	53/18639	0.207547169811321	1.53206799925276	0.095623692111807	0.458701995189731
GO:1901505	carbohydrate derivative transmembrane transporter activity	11/2525	53/18639	0.207547169811321	1.53206799925276	0.095623692111807	0.458701995189731
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/2525	24/18639	0.25	1.84544554455446	0.0958587760845413	0.458701995189731
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/2525	24/18639	0.25	1.84544554455446	0.0958587760845413	0.458701995189731
GO:0035035	histone acetyltransferase binding	6/2525	24/18639	0.25	1.84544554455446	0.0958587760845413	0.458701995189731
GO:0140033	acetylation-dependent protein binding	6/2525	24/18639	0.25	1.84544554455446	0.0958587760845413	0.458701995189731
GO:0019209	kinase activator activity	26/2525	148/18639	0.175675675675676	1.29679957184908	0.09728731536768	0.463819968468792
GO:0004860	protein kinase inhibitor activity	16/2525	84/18639	0.19047619047619	1.40605374823197	0.0976776642271367	0.463968905078899
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	44/2525	268/18639	0.164179104477612	1.2119343874686	0.100067207695801	0.469530674849715
GO:0005518	collagen binding	14/2525	72/18639	0.194444444444444	1.43534653465347	0.101755489509532	0.469530674849715
GO:0001968	fibronectin binding	7/2525	30/18639	0.233333333333333	1.72241584158416	0.10175587380644	0.469530674849715
GO:0035925	mRNA 3'-UTR AU-rich region binding	7/2525	30/18639	0.233333333333333	1.72241584158416	0.10175587380644	0.469530674849715
GO:0043995	histone H4K5 acetyltransferase activity	7/2525	30/18639	0.233333333333333	1.72241584158416	0.10175587380644	0.469530674849715
GO:0043996	histone H4K8 acetyltransferase activity	7/2525	30/18639	0.233333333333333	1.72241584158416	0.10175587380644	0.469530674849715
GO:0043997	histone H4K12 acetyltransferase activity	7/2525	30/18639	0.233333333333333	1.72241584158416	0.10175587380644	0.469530674849715
GO:0070566	adenylyltransferase activity	7/2525	30/18639	0.233333333333333	1.72241584158416	0.10175587380644	0.469530674849715
GO:0005520	insulin-like growth factor binding	5/2525	19/18639	0.263157894736842	1.94257425742574	0.103764371396469	0.477094547488393
GO:0000993	RNA polymerase II complex binding	8/2525	36/18639	0.222222222222222	1.64039603960396	0.10495007675218	0.480835103417791
GO:0051015	actin filament binding	35/2525	209/18639	0.167464114832536	1.23618361836184	0.106412625335911	0.485246833693497
GO:0140693	molecular condensate scaffold activity	10/2525	48/18639	0.208333333333333	1.53787128712871	0.106664164681852	0.485246833693497
GO:1902936	phosphatidylinositol bisphosphate binding	20/2525	111/18639	0.18018018018018	1.33005084292213	0.109836088408677	0.494091763625466
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/2525	14/18639	0.285714285714286	2.10908062234795	0.110184446308104	0.494091763625466
GO:0061665	SUMO ligase activity	4/2525	14/18639	0.285714285714286	2.10908062234795	0.110184446308104	0.494091763625466
GO:0043539	protein serine/threonine kinase activator activity	14/2525	73/18639	0.191780821917808	1.41568425335684	0.111001670555418	0.494091763625466
GO:0019001	guanyl nucleotide binding	63/2525	400/18639	0.1575	1.16263069306931	0.111214279754765	0.494091763625466
GO:0032561	guanyl ribonucleotide binding	63/2525	400/18639	0.1575	1.16263069306931	0.111214279754765	0.494091763625466
GO:0000287	magnesium ion binding	38/2525	230/18639	0.165217391304348	1.21959879466207	0.111285374005426	0.494091763625466
GO:0019902	phosphatase binding	32/2525	190/18639	0.168421052631579	1.24324752475248	0.111814014461455	0.494738721521231
GO:0003707	nuclear steroid receptor activity	6/2525	25/18639	0.24	1.77162772277228	0.112382106266368	0.495555226266713
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	16/2525	86/18639	0.186046511627907	1.37335482385448	0.11461905267796	0.502917707345625
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	12/2525	61/18639	0.19672131147541	1.45215387112482	0.115471045247401	0.502917707345625
GO:0019905	syntaxin binding	12/2525	61/18639	0.19672131147541	1.45215387112482	0.115471045247401	0.502917707345625
GO:0003714	transcription corepressor activity	34/2525	204/18639	0.166666666666667	1.23029702970297	0.115608791858863	0.502917707345625
GO:0035254	glutamate receptor binding	10/2525	49/18639	0.204081632653061	1.50648615881996	0.118606414425805	0.512506646950301
GO:0060590	ATPase regulator activity	10/2525	49/18639	0.204081632653061	1.50648615881996	0.118606414425805	0.512506646950301
GO:0004712	protein serine/threonine/tyrosine kinase activity	9/2525	43/18639	0.209302325581395	1.54502417683629	0.119241363246999	0.513532804383742
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/2525	20/18639	0.25	1.84544554455446	0.123678704291111	0.530610496230407
GO:0030295	protein kinase activator activity	24/2525	139/18639	0.172661870503597	1.27455231854121	0.124288617160254	0.530610496230407
GO:0033192	calmodulin-dependent protein phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:0140791	histone H2AXS140 phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:1990439	MAP kinase serine/threonine phosphatase activity	15/2525	81/18639	0.185185185185185	1.36699669966997	0.127313663956212	0.530610496230407
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/2525	26/18639	0.230769230769231	1.70348819497334	0.130241177347039	0.533281169136606
GO:0005160	transforming growth factor beta receptor binding	6/2525	26/18639	0.230769230769231	1.70348819497334	0.130241177347039	0.533281169136606
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/2525	26/18639	0.230769230769231	1.70348819497334	0.130241177347039	0.533281169136606
GO:0019865	immunoglobulin binding	6/2525	26/18639	0.230769230769231	1.70348819497334	0.130241177347039	0.533281169136606
GO:0030247	polysaccharide binding	6/2525	26/18639	0.230769230769231	1.70348819497334	0.130241177347039	0.533281169136606
GO:0044183	protein folding chaperone	14/2525	75/18639	0.186666666666667	1.37793267326733	0.130934798368901	0.533281169136606
GO:0015605	organophosphate ester transmembrane transporter activity	10/2525	50/18639	0.2	1.47635643564356	0.131256510669846	0.533281169136606
GO:0048020	CCR chemokine receptor binding	10/2525	50/18639	0.2	1.47635643564356	0.131256510669846	0.533281169136606
GO:0043014	alpha-tubulin binding	9/2525	44/18639	0.204545454545455	1.5099099909991	0.132889758921655	0.534479941093377
GO:0042826	histone deacetylase binding	22/2525	127/18639	0.173228346456693	1.27873392063616	0.133037619829657	0.534479941093377
GO:0070717	poly-purine tract binding	7/2525	32/18639	0.21875	1.61476485148515	0.133048893690826	0.534479941093377
GO:0004197	cysteine-type endopeptidase activity	16/2525	88/18639	0.181818181818182	1.34214221422142	0.133206301108411	0.534479941093377
GO:0043531	ADP binding	8/2525	38/18639	0.210526315789474	1.55405940594059	0.133651412025515	0.53460564810206
GO:0004129	cytochrome-c oxidase activity	4/2525	15/18639	0.266666666666667	1.96847524752475	0.134900367187561	0.53463581106236
GO:0050780	dopamine receptor binding	4/2525	15/18639	0.266666666666667	1.96847524752475	0.134900367187561	0.53463581106236
GO:0140776	protein-containing complex destabilizing activity	4/2525	15/18639	0.266666666666667	1.96847524752475	0.134900367187561	0.53463581106236
GO:0051087	protein-folding chaperone binding	23/2525	134/18639	0.171641791044776	1.26702231417172	0.13633574326755	0.538672111014295
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	15/2525	82/18639	0.182926829268293	1.35032600821058	0.137370806592892	0.539462255677861
GO:0033549	MAP kinase phosphatase activity	15/2525	82/18639	0.182926829268293	1.35032600821058	0.137370806592892	0.539462255677861
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/2525	57/18639	0.192982456140351	1.42455445544554	0.141459326758331	0.540580196492849
GO:0003713	transcription coactivator activity	41/2525	256/18639	0.16015625	1.1822385519802	0.142742099915483	0.540580196492849
GO:0001094	TFIID-class transcription factor complex binding	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0004090	carbonyl reductase (NADPH) activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0005345	purine nucleobase transmembrane transporter activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0008190	eukaryotic initiation factor 4E binding	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0016783	sulfurtransferase activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0031419	cobalamin binding	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0050308	sugar-phosphatase activity	3/2525	10/18639	0.3	2.21453465346535	0.143513163620005	0.540580196492849
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2525	21/18639	0.238095238095238	1.75756718528996	0.145202473375839	0.542201143357181
GO:0019200	carbohydrate kinase activity	5/2525	21/18639	0.238095238095238	1.75756718528996	0.145202473375839	0.542201143357181
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/2525	21/18639	0.238095238095238	1.75756718528996	0.145202473375839	0.542201143357181
GO:0051539	4 iron, 4 sulfur cluster binding	9/2525	45/18639	0.2	1.47635643564356	0.147314055145735	0.548500747113227
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	8/2525	39/18639	0.205128205128205	1.51421172886519	0.149351354059853	0.549780870463108
GO:0001671	ATPase activator activity	6/2525	27/18639	0.222222222222222	1.64039603960396	0.149359973322408	0.549780870463108
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/2525	27/18639	0.222222222222222	1.64039603960396	0.149359973322408	0.549780870463108
GO:0035255	ionotropic glutamate receptor binding	6/2525	27/18639	0.222222222222222	1.64039603960396	0.149359973322408	0.549780870463108
GO:0019956	chemokine binding	7/2525	33/18639	0.212121212121212	1.56583258325833	0.150280351049768	0.551597197603125
GO:0002020	protease binding	23/2525	136/18639	0.169117647058824	1.24838963308096	0.152661469490402	0.558749627709913
GO:0008408	3'-5' exonuclease activity	11/2525	58/18639	0.189655172413793	1.39999317173097	0.154465645067031	0.563755970131648
GO:0004527	exonuclease activity	15/2525	84/18639	0.178571428571429	1.31817538896747	0.158766955517085	0.576199175640658
GO:0017018	myosin phosphatase activity	15/2525	84/18639	0.178571428571429	1.31817538896747	0.158766955517085	0.576199175640658
GO:0003712	transcription coregulator activity	75/2525	495/18639	0.151515151515152	1.11845184518452	0.160743359829444	0.576777978137704
GO:0016922	nuclear receptor binding	23/2525	137/18639	0.167883211678832	1.23927729999277	0.161220129858793	0.576777978137704
GO:0005149	interleukin-1 receptor binding	4/2525	16/18639	0.25	1.84544554455446	0.16161324263872	0.576777978137704
GO:0005159	insulin-like growth factor receptor binding	4/2525	16/18639	0.25	1.84544554455446	0.16161324263872	0.576777978137704
GO:0005521	lamin binding	4/2525	16/18639	0.25	1.84544554455446	0.16161324263872	0.576777978137704
GO:0004180	carboxypeptidase activity	9/2525	46/18639	0.195652173913043	1.44426173052088	0.162483323001806	0.576777978137704
GO:0030291	protein serine/threonine kinase inhibitor activity	9/2525	46/18639	0.195652173913043	1.44426173052088	0.162483323001806	0.576777978137704
GO:0016791	phosphatase activity	43/2525	273/18639	0.157509157509158	1.1626982918072	0.16249782046604	0.576777978137704
GO:0042578	phosphoric ester hydrolase activity	56/2525	363/18639	0.154269972451791	1.13878733327878	0.163346267205025	0.577009684628944
GO:0004177	aminopeptidase activity	8/2525	40/18639	0.2	1.47635643564356	0.165896354970121	0.577009684628944
GO:0140662	ATP-dependent protein folding chaperone	8/2525	40/18639	0.2	1.47635643564356	0.165896354970121	0.577009684628944
GO:0045309	protein phosphorylated amino acid binding	11/2525	59/18639	0.186440677966102	1.37626447390502	0.168055250424901	0.577009684628944
GO:0070063	RNA polymerase binding	11/2525	59/18639	0.186440677966102	1.37626447390502	0.168055250424901	0.577009684628944
GO:0008649	rRNA methyltransferase activity	5/2525	22/18639	0.227272727272727	1.67767776777678	0.168191871141585	0.577009684628944
GO:0031683	G-protein beta/gamma-subunit complex binding	5/2525	22/18639	0.227272727272727	1.67767776777678	0.168191871141585	0.577009684628944
GO:0034062	5'-3' RNA polymerase activity	5/2525	22/18639	0.227272727272727	1.67767776777678	0.168191871141585	0.577009684628944
GO:0070034	telomerase RNA binding	5/2525	22/18639	0.227272727272727	1.67767776777678	0.168191871141585	0.577009684628944
GO:0097747	RNA polymerase activity	5/2525	22/18639	0.227272727272727	1.67767776777678	0.168191871141585	0.577009684628944
GO:0140035	ubiquitin-like protein reader activity	5/2525	22/18639	0.227272727272727	1.67767776777678	0.168191871141585	0.577009684628944
GO:0008376	acetylgalactosaminyltransferase activity	7/2525	34/18639	0.205882352941176	1.51977868375073	0.168490824050694	0.577009684628944
GO:0030332	cyclin binding	7/2525	34/18639	0.205882352941176	1.51977868375073	0.168490824050694	0.577009684628944
GO:0004725	protein tyrosine phosphatase activity	17/2525	98/18639	0.173469387755102	1.28051323499697	0.168815526927044	0.577009684628944
GO:0019789	SUMO transferase activity	6/2525	28/18639	0.214285714285714	1.58181046676096	0.169648270115419	0.578326028995043
GO:0042393	histone binding	39/2525	247/18639	0.157894736842105	1.16554455445545	0.172025555736261	0.579212183509992
GO:0005544	calcium-dependent phospholipid binding	10/2525	53/18639	0.188679245283019	1.39278909022978	0.173249201476495	0.579212183509992
GO:0034212	protein N-acetyltransferase activity	10/2525	53/18639	0.188679245283019	1.39278909022978	0.173249201476495	0.579212183509992
GO:0001216	DNA-binding transcription activator activity	74/2525	491/18639	0.15071283095723	1.11252928958884	0.174711545558669	0.579212183509992
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	73/2525	484/18639	0.150826446280992	1.11336797316095	0.174810634735902	0.579212183509992
GO:0001784	phosphotyrosine residue binding	9/2525	47/18639	0.191489361702128	1.41353275753107	0.178361271817877	0.579212183509992
GO:0005114	type II transforming growth factor beta receptor binding	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0005225	volume-sensitive anion channel activity	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0008199	ferric iron binding	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0010854	adenylate cyclase regulator activity	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0015205	nucleobase transmembrane transporter activity	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0019206	nucleoside kinase activity	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0032794	GTPase activating protein binding	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0034056	estrogen response element binding	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0048185	activin binding	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0180030	inositol phosphate kinase activity	3/2525	11/18639	0.272727272727273	2.01321332133213	0.178426044146267	0.579212183509992
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/2525	60/18639	0.183333333333333	1.35332673267327	0.182204220549782	0.589994618923104
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/2525	41/18639	0.195121951219512	1.44034774209128	0.183236922621295	0.591855260066783
GO:0051219	phosphoprotein binding	16/2525	93/18639	0.172043010752688	1.26998403066113	0.186583470705523	0.596080373822462
GO:0005154	epidermal growth factor receptor binding	7/2525	35/18639	0.2	1.47635643564356	0.187610806950147	0.596080373822462
GO:0003925	G protein activity	10/2525	54/18639	0.185185185185185	1.36699669966997	0.18850408003856	0.596080373822462
GO:0050661	NADP binding	10/2525	54/18639	0.185185185185185	1.36699669966997	0.18850408003856	0.596080373822462
GO:0004550	nucleoside diphosphate kinase activity	4/2525	17/18639	0.235294117647059	1.73688992428655	0.190040008252097	0.596080373822462
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/2525	17/18639	0.235294117647059	1.73688992428655	0.190040008252097	0.596080373822462
GO:0005092	GDP-dissociation inhibitor activity	4/2525	17/18639	0.235294117647059	1.73688992428655	0.190040008252097	0.596080373822462
GO:0017110	nucleoside diphosphate phosphatase activity	4/2525	17/18639	0.235294117647059	1.73688992428655	0.190040008252097	0.596080373822462
GO:0032182	ubiquitin-like protein binding	20/2525	120/18639	0.166666666666667	1.23029702970297	0.190320459521081	0.596080373822462
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	36/2525	229/18639	0.157205240174672	1.16045484024385	0.190526997982578	0.596080373822462
GO:0043130	ubiquitin binding	17/2525	100/18639	0.17	1.25490297029703	0.190790700390622	0.596080373822462
GO:0016417	S-acyltransferase activity	6/2525	29/18639	0.206896551724138	1.52726527825196	0.191004082633513	0.596080373822462
GO:0043236	laminin binding	6/2525	29/18639	0.206896551724138	1.52726527825196	0.191004082633513	0.596080373822462
GO:0051861	glycolipid binding	6/2525	29/18639	0.206896551724138	1.52726527825196	0.191004082633513	0.596080373822462
GO:0140102	catalytic activity, acting on a rRNA	5/2525	23/18639	0.217391304347826	1.60473525613431	0.192486653653311	0.597819126250187
GO:0140103	catalytic activity, acting on a glycoprotein	5/2525	23/18639	0.217391304347826	1.60473525613431	0.192486653653311	0.597819126250187
GO:0004866	endopeptidase inhibitor activity	26/2525	161/18639	0.161490683229814	1.19208904741406	0.194520371804718	0.602439070429205
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	9/2525	48/18639	0.1875	1.38408415841584	0.194906758080037	0.602439070429205
GO:0045296	cadherin binding	51/2525	334/18639	0.152694610778443	1.12715835655422	0.196793941266124	0.606820458510339
GO:0004402	histone acetyltransferase activity	8/2525	42/18639	0.19047619047619	1.40605374823197	0.201317615049227	0.613448959065099
GO:0004520	DNA endonuclease activity	8/2525	42/18639	0.19047619047619	1.40605374823197	0.201317615049227	0.613448959065099
GO:0043175	RNA polymerase core enzyme binding	8/2525	42/18639	0.19047619047619	1.40605374823197	0.201317615049227	0.613448959065099
GO:0048487	beta-tubulin binding	8/2525	42/18639	0.19047619047619	1.40605374823197	0.201317615049227	0.613448959065099
GO:0051879	Hsp90 protein binding	8/2525	42/18639	0.19047619047619	1.40605374823197	0.201317615049227	0.613448959065099
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	21/2525	128/18639	0.1640625	1.21107363861386	0.203359023559458	0.618211431620752
GO:0004869	cysteine-type endopeptidase inhibitor activity	7/2525	36/18639	0.194444444444444	1.43534653465347	0.207563396997932	0.629511523289502
GO:0015631	tubulin binding	58/2525	385/18639	0.150649350649351	1.11206069178346	0.208802445955966	0.6317863235951
GO:0008187	poly-pyrimidine tract binding	6/2525	30/18639	0.2	1.47635643564356	0.213316134840282	0.63186810737485
GO:0004300	enoyl-CoA hydratase activity	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0005049	nuclear export signal receptor activity	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0005247	voltage-gated chloride channel activity	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0015269	calcium-activated potassium channel activity	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0016273	arginine N-methyltransferase activity	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0016274	protein-arginine N-methyltransferase activity	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0034452	dynactin binding	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0045295	gamma-catenin binding	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0070410	co-SMAD binding	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0097677	STAT family protein binding	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:1990459	transferrin receptor binding	3/2525	12/18639	0.25	1.84544554455446	0.215320178372614	0.63186810737485
GO:0005315	phosphate transmembrane transporter activity	5/2525	24/18639	0.208333333333333	1.53787128712871	0.217915042487198	0.63186810737485
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	15/2525	89/18639	0.168539325842697	1.24412059183446	0.21920775016403	0.63186810737485
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	15/2525	89/18639	0.168539325842697	1.24412059183446	0.21920775016403	0.63186810737485
GO:0008308	voltage-gated monoatomic anion channel activity	4/2525	18/18639	0.222222222222222	1.64039603960396	0.219885233574668	0.63186810737485
GO:0008409	5'-3' exonuclease activity	4/2525	18/18639	0.222222222222222	1.64039603960396	0.219885233574668	0.63186810737485
GO:0017075	syntaxin-1 binding	4/2525	18/18639	0.222222222222222	1.64039603960396	0.219885233574668	0.63186810737485
GO:0030228	lipoprotein particle receptor activity	4/2525	18/18639	0.222222222222222	1.64039603960396	0.219885233574668	0.63186810737485
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	4/2525	18/18639	0.222222222222222	1.64039603960396	0.219885233574668	0.63186810737485
GO:0050811	GABA receptor binding	4/2525	18/18639	0.222222222222222	1.64039603960396	0.219885233574668	0.63186810737485
GO:0048156	tau protein binding	8/2525	43/18639	0.186046511627907	1.37335482385448	0.220077901175451	0.63186810737485
GO:0004722	protein serine/threonine phosphatase activity	17/2525	103/18639	0.16504854368932	1.21835239834663	0.226181338112228	0.647951859957869
GO:0019955	cytokine binding	23/2525	144/18639	0.159722222222222	1.17903465346535	0.228053478607281	0.651869677788955
GO:0008017	microtubule binding	42/2525	276/18639	0.152173913043478	1.12331467929402	0.230169488993558	0.656465739027985
GO:0140793	histone H2AXY142 phosphatase activity	15/2525	90/18639	0.166666666666667	1.23029702970297	0.232368437402917	0.661277579569535
GO:0016411	acylglycerol O-acyltransferase activity	6/2525	31/18639	0.193548387096774	1.42873203449377	0.236466282833633	0.671460302024295
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/2525	25/18639	0.2	1.47635643564356	0.244298276542405	0.687654408045289
GO:0019706	protein-cysteine S-palmitoyltransferase activity	5/2525	25/18639	0.2	1.47635643564356	0.244298276542405	0.687654408045289
GO:0019707	protein-cysteine S-acyltransferase activity	5/2525	25/18639	0.2	1.47635643564356	0.244298276542405	0.687654408045289
GO:0120020	cholesterol transfer activity	5/2525	25/18639	0.2	1.47635643564356	0.244298276542405	0.687654408045289
GO:0140101	catalytic activity, acting on a tRNA	22/2525	139/18639	0.158273381294964	1.16833962532944	0.247986461486601	0.692705412711816
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/2525	19/18639	0.210526315789474	1.55405940594059	0.250850796822187	0.692705412711816
GO:0043395	heparan sulfate proteoglycan binding	4/2525	19/18639	0.210526315789474	1.55405940594059	0.250850796822187	0.692705412711816
GO:0140036	ubiquitin-modified protein reader activity	4/2525	19/18639	0.210526315789474	1.55405940594059	0.250850796822187	0.692705412711816
GO:0004535	poly(A)-specific ribonuclease activity	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0008035	high-density lipoprotein particle binding	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0017154	semaphorin receptor activity	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0019855	calcium channel inhibitor activity	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0035673	oligopeptide transmembrane transporter activity	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0071837	HMG box domain binding	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0140333	glycerophospholipid flippase activity	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/2525	13/18639	0.230769230769231	1.70348819497334	0.253598808214155	0.692705412711816
GO:0046915	transition metal ion transmembrane transporter activity	8/2525	45/18639	0.177777777777778	1.31231683168317	0.259374987412632	0.705875469139923
GO:0022804	active transmembrane transporter activity	67/2525	457/18639	0.146608315098468	1.08223064757242	0.259513040124972	0.705875469139923
GO:0004721	phosphoprotein phosphatase activity	27/2525	175/18639	0.154285714285714	1.13890353606789	0.26236476241249	0.712132926548186
GO:0004435	phosphatidylinositol phospholipase C activity	5/2525	26/18639	0.192307692307692	1.41957349581112	0.271454728731778	0.72613923969803
GO:0004529	DNA exonuclease activity	5/2525	26/18639	0.192307692307692	1.41957349581112	0.271454728731778	0.72613923969803
GO:0008143	poly(A) binding	5/2525	26/18639	0.192307692307692	1.41957349581112	0.271454728731778	0.72613923969803
GO:0008157	protein phosphatase 1 binding	5/2525	26/18639	0.192307692307692	1.41957349581112	0.271454728731778	0.72613923969803
GO:0030414	peptidase inhibitor activity	26/2525	169/18639	0.153846153846154	1.1356587966489	0.272293591540408	0.72613923969803
GO:0004879	nuclear receptor activity	10/2525	59/18639	0.169491525423729	1.25114952173183	0.272583228524415	0.72613923969803
GO:0015459	potassium channel regulator activity	10/2525	59/18639	0.169491525423729	1.25114952173183	0.272583228524415	0.72613923969803
GO:0031593	polyubiquitin modification-dependent protein binding	10/2525	59/18639	0.169491525423729	1.25114952173183	0.272583228524415	0.72613923969803
GO:0070888	E-box binding	10/2525	59/18639	0.169491525423729	1.25114952173183	0.272583228524415	0.72613923969803
GO:0051213	dioxygenase activity	15/2525	93/18639	0.161290322580645	1.19061002874481	0.273660264972737	0.727508358734108
GO:0015095	magnesium ion transmembrane transporter activity	4/2525	20/18639	0.2	1.47635643564356	0.282643819954956	0.744407079186528
GO:0016004	phospholipase activator activity	4/2525	20/18639	0.2	1.47635643564356	0.282643819954956	0.744407079186528
GO:0016408	C-acyltransferase activity	4/2525	20/18639	0.2	1.47635643564356	0.282643819954956	0.744407079186528
GO:0052745	inositol phosphate phosphatase activity	4/2525	20/18639	0.2	1.47635643564356	0.282643819954956	0.744407079186528
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/2525	53/18639	0.169811320754717	1.2535101812068	0.285938856863826	0.744407079186528
GO:0098531	ligand-modulated transcription factor activity	10/2525	60/18639	0.166666666666667	1.23029702970297	0.290659030119342	0.744407079186528
GO:0005313	L-glutamate transmembrane transporter activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0005347	ATP transmembrane transporter activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0005545	1-phosphatidylinositol binding	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0008174	mRNA methyltransferase activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0008474	palmitoyl-(protein) hydrolase activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0015926	glucosidase activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0016530	metallochaperone activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0019763	immunoglobulin receptor activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0019992	diacylglycerol binding	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0034236	protein kinase A catalytic subunit binding	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0044548	S100 protein binding	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0070742	C2H2 zinc finger domain binding	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0071933	Arp2/3 complex binding	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0098599	palmitoyl hydrolase activity	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:1901612	cardiolipin binding	3/2525	14/18639	0.214285714285714	1.58181046676096	0.292711816006715	0.744407079186528
GO:0140789	histone phosphatase activity	21/2525	136/18639	0.154411764705882	1.13983401281305	0.293268733208934	0.744407079186528
GO:0140104	molecular carrier activity	37/2525	249/18639	0.14859437751004	1.09689132768699	0.297316756530294	0.752083598285869
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/2525	27/18639	0.185185185185185	1.36699669966997	0.299203536779363	0.752083598285869
GO:0008266	poly(U) RNA binding	5/2525	27/18639	0.185185185185185	1.36699669966997	0.299203536779363	0.752083598285869
GO:0015252	proton channel activity	5/2525	27/18639	0.185185185185185	1.36699669966997	0.299203536779363	0.752083598285869
GO:0016405	CoA-ligase activity	5/2525	27/18639	0.185185185185185	1.36699669966997	0.299203536779363	0.752083598285869
GO:0009055	electron transfer activity	18/2525	116/18639	0.155172413793103	1.14544895868897	0.304785699996255	0.763269147775071
GO:0019903	protein phosphatase binding	22/2525	144/18639	0.152777777777778	1.12777227722772	0.305314116632682	0.763269147775071
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	9/2525	54/18639	0.166666666666667	1.23029702970297	0.305425812228879	0.763269147775071
GO:0052866	phosphatidylinositol phosphate phosphatase activity	6/2525	34/18639	0.176470588235294	1.30266744321491	0.30970848258357	0.772477527988363
GO:0008373	sialyltransferase activity	4/2525	21/18639	0.19047619047619	1.40605374823197	0.314982960326513	0.781109375704137
GO:0070182	DNA polymerase binding	4/2525	21/18639	0.19047619047619	1.40605374823197	0.314982960326513	0.781109375704137
GO:0140312	cargo adaptor activity	4/2525	21/18639	0.19047619047619	1.40605374823197	0.314982960326513	0.781109375704137
GO:0042287	MHC protein binding	7/2525	41/18639	0.170731707317073	1.26030427432987	0.316781290283998	0.783622135199121
GO:0016407	acetyltransferase activity	15/2525	96/18639	0.15625	1.15340346534653	0.317209269898716	0.783622135199121
GO:0008374	O-acyltransferase activity	9/2525	55/18639	0.163636363636364	1.20792799279928	0.325204897549084	0.790343948893669
GO:0046875	ephrin receptor binding	5/2525	28/18639	0.178571428571429	1.31817538896747	0.327367725184567	0.790343948893669
GO:0046966	nuclear thyroid hormone receptor binding	5/2525	28/18639	0.178571428571429	1.31817538896747	0.327367725184567	0.790343948893669
GO:0051959	dynein light intermediate chain binding	5/2525	28/18639	0.178571428571429	1.31817538896747	0.327367725184567	0.790343948893669
GO:0002039	p53 binding	11/2525	69/18639	0.159420289855072	1.17680585449849	0.329454350566928	0.790343948893669
GO:0008080	N-acetyltransferase activity	11/2525	69/18639	0.159420289855072	1.17680585449849	0.329454350566928	0.790343948893669
GO:0051536	iron-sulfur cluster binding	12/2525	76/18639	0.157894736842105	1.16554455445545	0.330665238562155	0.790343948893669
GO:0030165	PDZ domain binding	13/2525	83/18639	0.156626506024096	1.1561827508052	0.331455763591737	0.790343948893669
GO:0000774	adenyl-nucleotide exchange factor activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0005041	low-density lipoprotein particle receptor activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0008252	nucleotidase activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0016846	carbon-sulfur lyase activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0031386	protein tag activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0033130	acetylcholine receptor binding	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0048531	beta-1,3-galactosyltransferase activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0120283	protein serine/threonine kinase binding	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0141047	molecular tag activity	3/2525	15/18639	0.2	1.47635643564356	0.332164678211503	0.790343948893669
GO:0043015	gamma-tubulin binding	6/2525	35/18639	0.171428571428571	1.26544837340877	0.334970070645657	0.795553917783436
GO:0019894	kinesin binding	7/2525	42/18639	0.166666666666667	1.23029702970297	0.339874025330952	0.805719707757046
GO:0001664	G protein-coupled receptor binding	43/2525	297/18639	0.144781144781145	1.06874287428743	0.343017183583899	0.8116816871619
GO:0008170	N-methyltransferase activity	15/2525	98/18639	0.153061224489796	1.12986461911497	0.347184317417046	0.816795924183884
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2525	22/18639	0.181818181818182	1.34214221422142	0.347603202367608	0.816795924183884
GO:0003724	RNA helicase activity	12/2525	77/18639	0.155844155844156	1.15040761218979	0.347707243267133	0.816795924183884
GO:0051540	metal cluster binding	12/2525	77/18639	0.155844155844156	1.15040761218979	0.347707243267133	0.816795924183884
GO:0004629	phospholipase C activity	5/2525	29/18639	0.172413793103448	1.27272106520997	0.355776817382704	0.834235295931856
GO:0004033	aldo-keto reductase (NADPH) activity	6/2525	36/18639	0.166666666666667	1.23029702970297	0.360451405375203	0.838435219296219
GO:0003688	DNA replication origin binding	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0004708	MAP kinase kinase activity	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0008142	oxysterol binding	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0016722	oxidoreductase activity, acting on metal ions	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0070411	I-SMAD binding	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0097027	ubiquitin-protein transferase activator activity	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0140327	flippase activity	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0140328	floppase activity	3/2525	16/18639	0.1875	1.38408415841584	0.371522701805222	0.838435219296219
GO:0003697	single-stranded DNA binding	18/2525	121/18639	0.148760330578512	1.09811635709025	0.372829950179718	0.838435219296219
GO:0051082	unfolded protein binding	18/2525	121/18639	0.148760330578512	1.09811635709025	0.372829950179718	0.838435219296219
GO:0005516	calmodulin binding	30/2525	207/18639	0.144927536231884	1.06982350408954	0.37457865456573	0.838435219296219
GO:0016887	ATP hydrolysis activity	59/2525	417/18639	0.141486810551559	1.04442481658238	0.379753900469316	0.838435219296219
GO:0004602	glutathione peroxidase activity	4/2525	23/18639	0.173913043478261	1.28378820490745	0.380259317886408	0.838435219296219
GO:0005158	insulin receptor binding	4/2525	23/18639	0.173913043478261	1.28378820490745	0.380259317886408	0.838435219296219
GO:0008171	O-methyltransferase activity	4/2525	23/18639	0.173913043478261	1.28378820490745	0.380259317886408	0.838435219296219
GO:0016849	phosphorus-oxygen lyase activity	4/2525	23/18639	0.173913043478261	1.28378820490745	0.380259317886408	0.838435219296219
GO:0008186	ATP-dependent activity, acting on RNA	12/2525	79/18639	0.151898734177215	1.12128336884321	0.382201172475861	0.838435219296219
GO:0001965	G-protein alpha-subunit binding	5/2525	30/18639	0.166666666666667	1.23029702970297	0.384268953891188	0.838435219296219
GO:0008106	alcohol dehydrogenase (NADP+) activity	5/2525	30/18639	0.166666666666667	1.23029702970297	0.384268953891188	0.838435219296219
GO:0051721	protein phosphatase 2A binding	5/2525	30/18639	0.166666666666667	1.23029702970297	0.384268953891188	0.838435219296219
GO:0038024	cargo receptor activity	10/2525	65/18639	0.153846153846154	1.1356587966489	0.384727901959358	0.838435219296219
GO:0120013	lipid transfer activity	10/2525	65/18639	0.153846153846154	1.1356587966489	0.384727901959358	0.838435219296219
GO:0001223	transcription coactivator binding	7/2525	44/18639	0.159090909090909	1.17437443744374	0.386573194670943	0.838435219296219
GO:0016790	thiolester hydrolase activity	7/2525	44/18639	0.159090909090909	1.17437443744374	0.386573194670943	0.838435219296219
GO:0008234	cysteine-type peptidase activity	27/2525	187/18639	0.144385026737968	1.06581881717584	0.391828325412698	0.838435219296219
GO:0008081	phosphoric diester hydrolase activity	13/2525	87/18639	0.149425287356322	1.10302492318197	0.397397237772281	0.838435219296219
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0004382	GDP phosphatase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0005528	FK506 binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0008140	cAMP response element binding protein binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0008519	ammonium channel activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0015279	store-operated calcium channel activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0016427	tRNA (cytidine) methyltransferase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0030957	Tat protein binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0031956	medium-chain fatty acid-CoA ligase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0035256	G protein-coupled glutamate receptor binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0043208	glycosphingolipid binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0051880	G-quadruplex DNA binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0071723	lipopeptide binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0140940	histone H2A methyltransferase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0140999	histone H3K4 trimethyltransferase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0141109	transporter activator activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:1905394	retromer complex binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:1990259	histone H2AQ104 methyltransferase activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:1990757	ubiquitin ligase activator activity	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:1990763	arrestin family protein binding	2/2525	10/18639	0.2	1.47635643564356	0.401298360339673	0.838435219296219
GO:0140597	protein carrier chaperone	27/2525	188/18639	0.143617021276596	1.0601495681483	0.403153394276205	0.838435219296219
GO:0001786	phosphatidylserine binding	9/2525	59/18639	0.152542372881356	1.12603456955865	0.406068281637985	0.838435219296219
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/2525	59/18639	0.152542372881356	1.12603456955865	0.406068281637985	0.838435219296219
GO:0036002	pre-mRNA binding	9/2525	59/18639	0.152542372881356	1.12603456955865	0.406068281637985	0.838435219296219
GO:0008194	UDP-glycosyltransferase activity	21/2525	145/18639	0.144827586206897	1.06908569477637	0.406493128194457	0.838435219296219
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0008484	sulfuric ester hydrolase activity	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0019198	transmembrane receptor protein phosphatase activity	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0030169	low-density lipoprotein particle binding	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0031489	myosin V binding	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0032183	SUMO binding	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0045125	bioactive lipid receptor activity	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0046965	nuclear retinoid X receptor binding	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0051787	misfolded protein binding	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0070403	NAD+ binding	3/2525	17/18639	0.176470588235294	1.30266744321491	0.41041185042375	0.838435219296219
GO:0005109	frizzled binding	6/2525	38/18639	0.157894736842105	1.16554455445545	0.411611771451126	0.838435219296219
GO:0016878	acid-thiol ligase activity	5/2525	31/18639	0.161290322580645	1.19061002874481	0.412692544479179	0.838435219296219
GO:0004622	lysophospholipase activity	4/2525	24/18639	0.166666666666667	1.23029702970297	0.41272817296625	0.838435219296219
GO:0015295	solute:proton symporter activity	4/2525	24/18639	0.166666666666667	1.23029702970297	0.41272817296625	0.838435219296219
GO:0019957	C-C chemokine binding	4/2525	24/18639	0.166666666666667	1.23029702970297	0.41272817296625	0.838435219296219
GO:0060229	lipase activator activity	4/2525	24/18639	0.166666666666667	1.23029702970297	0.41272817296625	0.838435219296219
GO:0070300	phosphatidic acid binding	4/2525	24/18639	0.166666666666667	1.23029702970297	0.41272817296625	0.838435219296219
GO:0070840	dynein complex binding	4/2525	24/18639	0.166666666666667	1.23029702970297	0.41272817296625	0.838435219296219
GO:0030971	receptor tyrosine kinase binding	12/2525	81/18639	0.148148148148148	1.09359735973597	0.417004514902234	0.845792516881768
GO:0035064	methylated histone binding	11/2525	74/18639	0.148648648648649	1.09729194541076	0.420030724645957	0.850595135176452
GO:0016758	hexosyltransferase activity	28/2525	197/18639	0.142131979695431	1.04918731467055	0.423002616172323	0.855272895296778
GO:0051018	protein kinase A binding	8/2525	53/18639	0.150943396226415	1.11423127218382	0.429834189567394	0.864147843560073
GO:0003727	single-stranded RNA binding	13/2525	89/18639	0.146067415730337	1.07823784625654	0.430785341321348	0.864147843560073
GO:0031369	translation initiation factor binding	5/2525	32/18639	0.15625	1.15340346534653	0.440907490831938	0.864147843560073
GO:0043425	bHLH transcription factor binding	5/2525	32/18639	0.15625	1.15340346534653	0.440907490831938	0.864147843560073
GO:0071813	lipoprotein particle binding	5/2525	32/18639	0.15625	1.15340346534653	0.440907490831938	0.864147843560073
GO:0071814	protein-lipid complex binding	5/2525	32/18639	0.15625	1.15340346534653	0.440907490831938	0.864147843560073
GO:0140142	nucleocytoplasmic carrier activity	5/2525	32/18639	0.15625	1.15340346534653	0.440907490831938	0.864147843560073
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	10/2525	68/18639	0.147058823529412	1.08555620267909	0.44237818344479	0.864147843560073
GO:0008139	nuclear localization sequence binding	4/2525	25/18639	0.16	1.18108514851485	0.444810057999363	0.864147843560073
GO:0015645	fatty acid ligase activity	4/2525	25/18639	0.16	1.18108514851485	0.444810057999363	0.864147843560073
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/2525	25/18639	0.16	1.18108514851485	0.444810057999363	0.864147843560073
GO:0120515	fatty acid-CoA ligase activity	4/2525	25/18639	0.16	1.18108514851485	0.444810057999363	0.864147843560073
GO:0016836	hydro-lyase activity	9/2525	61/18639	0.147540983606557	1.08911540334361	0.446751882520534	0.864147843560073
GO:0000400	four-way junction DNA binding	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:0015172	acidic amino acid transmembrane transporter activity	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:0031690	adrenergic receptor binding	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:0032393	MHC class I receptor activity	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:0035615	clathrin adaptor activity	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:0070628	proteasome binding	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:0098641	cadherin binding involved in cell-cell adhesion	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:1901611	phosphatidylglycerol binding	3/2525	18/18639	0.166666666666667	1.23029702970297	0.448517173793566	0.864147843560073
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0015217	ADP transmembrane transporter activity	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0034713	type I transforming growth factor beta receptor binding	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0050786	RAGE receptor binding	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0050998	nitric-oxide synthase binding	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2525	11/18639	0.181818181818182	1.34214221422142	0.450825541715985	0.864147843560073
GO:0051287	NAD binding	8/2525	54/18639	0.148148148148148	1.09359735973597	0.451470429104527	0.864147843560073
GO:0017022	myosin binding	11/2525	76/18639	0.144736842105263	1.06841584158416	0.456500852459736	0.867577818260823
GO:0140034	methylation-dependent protein binding	11/2525	76/18639	0.144736842105263	1.06841584158416	0.456500852459736	0.867577818260823
GO:0016829	lyase activity	28/2525	200/18639	0.14	1.0334495049505	0.456618303066766	0.867577818260823
GO:0043495	protein-membrane adaptor activity	7/2525	47/18639	0.148936170212766	1.09941436696861	0.456619904347802	0.867577818260823
GO:0140938	histone H3 methyltransferase activity	7/2525	47/18639	0.148936170212766	1.09941436696861	0.456619904347802	0.867577818260823
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6/2525	40/18639	0.15	1.10726732673267	0.462326406175068	0.872008345661589
GO:0050997	quaternary ammonium group binding	6/2525	40/18639	0.15	1.10726732673267	0.462326406175068	0.872008345661589
GO:0061791	GTPase motor activity	6/2525	40/18639	0.15	1.10726732673267	0.462326406175068	0.872008345661589
GO:0071949	FAD binding	6/2525	40/18639	0.15	1.10726732673267	0.462326406175068	0.872008345661589
GO:1990606	membrane scission GTPase motor activity	6/2525	40/18639	0.15	1.10726732673267	0.462326406175068	0.872008345661589
GO:0140713	histone chaperone activity	23/2525	164/18639	0.140243902439024	1.03524993962811	0.463263252633529	0.872501636155277
GO:0030296	protein tyrosine kinase activator activity	5/2525	33/18639	0.151515151515152	1.11845184518452	0.468786021460309	0.881617961756506
GO:0008013	beta-catenin binding	15/2525	106/18639	0.141509433962264	1.04459181767233	0.470381519927848	0.88333273800404
GO:0030507	spectrin binding	4/2525	26/18639	0.153846153846154	1.1356587966489	0.476329208775287	0.887339566599972
GO:0070006	metalloaminopeptidase activity	4/2525	26/18639	0.153846153846154	1.1356587966489	0.476329208775287	0.887339566599972
GO:0000510	H3-H4 histone complex chaperone activity	21/2525	151/18639	0.139072847682119	1.02660546849387	0.484336825913924	0.887339566599972
GO:0140584	chromatin extrusion motor activity	21/2525	151/18639	0.139072847682119	1.02660546849387	0.484336825913924	0.887339566599972
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	21/2525	151/18639	0.139072847682119	1.02660546849387	0.484336825913924	0.887339566599972
GO:0140849	ATP-dependent H2AZ histone chaperone activity	21/2525	151/18639	0.139072847682119	1.02660546849387	0.484336825913924	0.887339566599972
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2525	19/18639	0.157894736842105	1.16554455445545	0.485579619475699	0.887339566599972
GO:0008301	DNA binding, bending	3/2525	19/18639	0.157894736842105	1.16554455445545	0.485579619475699	0.887339566599972
GO:0008574	plus-end-directed microtubule motor activity	3/2525	19/18639	0.157894736842105	1.16554455445545	0.485579619475699	0.887339566599972
GO:0042800	histone H3K4 methyltransferase activity	3/2525	19/18639	0.157894736842105	1.16554455445545	0.485579619475699	0.887339566599972
GO:0042834	peptidoglycan binding	3/2525	19/18639	0.157894736842105	1.16554455445545	0.485579619475699	0.887339566599972
GO:0097001	ceramide binding	3/2525	19/18639	0.157894736842105	1.16554455445545	0.485579619475699	0.887339566599972
GO:0019212	phosphatase inhibitor activity	8/2525	56/18639	0.142857142857143	1.05454031117397	0.494253332970782	0.887339566599972
GO:0015616	DNA translocase activity	21/2525	152/18639	0.138157894736842	1.01985148514851	0.497233122663443	0.887339566599972
GO:0140674	ATP-dependent histone chaperone activity	21/2525	152/18639	0.138157894736842	1.01985148514851	0.497233122663443	0.887339566599972
GO:0003720	telomerase activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0004000	adenosine deaminase activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0004032	aldose reductase (NADPH) activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0005025	transforming growth factor beta receptor activity, type I	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0005026	transforming growth factor beta receptor activity, type II	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0005436	sodium:phosphate symporter activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0005527	macrolide binding	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0008179	adenylate cyclase binding	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0010853	cyclase activator activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0016208	AMP binding	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0016361	activin receptor activity, type I	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0016362	activin receptor activity, type II	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0016801	hydrolase activity, acting on ether bonds	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0016803	ether hydrolase activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0017002	activin receptor activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0035197	siRNA binding	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0036009	protein-glutamine N-methyltransferase activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:1990817	poly(A) RNA polymerase activity	2/2525	12/18639	0.166666666666667	1.23029702970297	0.497926614384659	0.887339566599972
GO:0016298	lipase activity	18/2525	130/18639	0.138461538461538	1.02209291698401	0.49898569252739	0.888002086426154
GO:0050660	flavin adenine dinucleotide binding	12/2525	86/18639	0.13953488372093	1.03001611789086	0.503582055750917	0.89494912796449
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/2525	27/18639	0.148148148148148	1.09359735973597	0.507133673470231	0.900022947971893
GO:0061775	cohesin loader activity	21/2525	153/18639	0.137254901960784	1.01318578916715	0.510071984723773	0.903995890621557
GO:0042056	chemoattractant activity	6/2525	42/18639	0.142857142857143	1.05454031117397	0.511844159493968	0.905894046666037
GO:0016410	N-acyltransferase activity	13/2525	94/18639	0.138297872340426	1.020884769328	0.51356646013062	0.907698859765747
GO:0004601	peroxidase activity	8/2525	57/18639	0.140350877192982	1.0360396039604	0.515290045494365	0.909501009260547
GO:0005178	integrin binding	22/2525	161/18639	0.136645962732919	1.00869073242728	0.517573139683196	0.912284442661241
GO:0010851	cyclase regulator activity	3/2525	20/18639	0.15	1.10726732673267	0.521391819391125	0.913281688921861
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/2525	20/18639	0.15	1.10726732673267	0.521391819391125	0.913281688921861
GO:0030742	GTP-dependent protein binding	3/2525	20/18639	0.15	1.10726732673267	0.521391819391125	0.913281688921861
GO:0140939	histone H4 methyltransferase activity	3/2525	20/18639	0.15	1.10726732673267	0.521391819391125	0.913281688921861
GO:0005506	iron ion binding	21/2525	154/18639	0.136363636363636	1.00660666066607	0.522840914553041	0.913281688921861
GO:0034061	DNA polymerase activity	5/2525	35/18639	0.142857142857143	1.05454031117397	0.523087035450602	0.913281688921861
GO:0140566	histone reader activity	5/2525	35/18639	0.142857142857143	1.05454031117397	0.523087035450602	0.913281688921861
GO:0008276	protein methyltransferase activity	13/2525	95/18639	0.136842105263158	1.01013861386139	0.529786623570214	0.923209497518189
GO:0061980	regulatory RNA binding	8/2525	58/18639	0.137931034482759	1.01817685216798	0.536023467990768	0.923209497518189
GO:0046625	sphingolipid binding	4/2525	28/18639	0.142857142857143	1.05454031117397	0.537094664851174	0.923209497518189
GO:0050698	proteoglycan sulfotransferase activity	4/2525	28/18639	0.142857142857143	1.05454031117397	0.537094664851174	0.923209497518189
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0003964	RNA-directed DNA polymerase activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0008253	5'-nucleotidase activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0008417	fucosyltransferase activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0031432	titin binding	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0043560	insulin receptor substrate binding	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0046974	histone H3K9 methyltransferase activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0046975	histone H3K36 methyltransferase activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0061459	L-arginine transmembrane transporter activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0070123	transforming growth factor beta receptor activity, type III	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0071714	icosanoid transmembrane transporter activity	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0089720	caspase binding	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0097157	pre-mRNA intronic binding	2/2525	13/18639	0.153846153846154	1.1356587966489	0.542349851870205	0.923209497518189
GO:0008235	metalloexopeptidase activity	9/2525	66/18639	0.136363636363636	1.00660666066607	0.545907615929416	0.927223856094803
GO:0016597	amino acid binding	7/2525	51/18639	0.137254901960784	1.01318578916715	0.546861128749412	0.927223856094803
GO:0016830	carbon-carbon lyase activity	7/2525	51/18639	0.137254901960784	1.01318578916715	0.546861128749412	0.927223856094803
GO:0055106	ubiquitin-protein transferase regulator activity	5/2525	36/18639	0.138888888888889	1.02524752475248	0.549318588688569	0.930169877569634
GO:0003684	damaged DNA binding	10/2525	74/18639	0.135135135135135	0.997538132191597	0.554799178373477	0.937447700137397
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/2525	21/18639	0.142857142857143	1.05454031117397	0.555793295901893	0.937447700137397
GO:0015174	basic amino acid transmembrane transporter activity	3/2525	21/18639	0.142857142857143	1.05454031117397	0.555793295901893	0.937447700137397
GO:0140097	catalytic activity, acting on DNA	45/2525	336/18639	0.133928571428571	0.988631541725601	0.557717971671053	0.939467561146023
GO:0043022	ribosome binding	15/2525	112/18639	0.133928571428571	0.988631541725601	0.561001003356838	0.943767312938848
GO:0042054	histone methyltransferase activity	9/2525	67/18639	0.134328358208955	0.991582680656125	0.564953027991151	0.947420119710362
GO:0050840	extracellular matrix binding	9/2525	67/18639	0.134328358208955	0.991582680656125	0.564953027991151	0.947420119710362
GO:0004181	metallocarboxypeptidase activity	4/2525	29/18639	0.137931034482759	1.01817685216798	0.56610552044613	0.947420119710362
GO:0106222	lncRNA binding	4/2525	29/18639	0.137931034482759	1.01817685216798	0.56610552044613	0.947420119710362
GO:0005080	protein kinase C binding	7/2525	52/18639	0.134615384615385	0.993701447067784	0.568443993767411	0.948875503808134
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/2525	52/18639	0.134615384615385	0.993701447067784	0.568443993767411	0.948875503808134
GO:0140658	ATP-dependent chromatin remodeler activity	21/2525	158/18639	0.132911392405063	0.981122947737812	0.572981289485153	0.952615402784819
GO:0031490	chromatin DNA binding	17/2525	128/18639	0.1328125	0.980392945544554	0.574376120569939	0.952615402784819
GO:0019213	deacetylase activity	5/2525	37/18639	0.135135135135135	0.997538132191597	0.57483153442673	0.952615402784819
GO:0043394	proteoglycan binding	5/2525	37/18639	0.135135135135135	0.997538132191597	0.57483153442673	0.952615402784819
GO:0140303	intramembrane lipid transporter activity	6/2525	45/18639	0.133333333333333	0.984237623762376	0.582545784960049	0.952615402784819
GO:0140223	general transcription initiation factor activity	9/2525	68/18639	0.132352941176471	0.977000582411182	0.583650885633816	0.952615402784819
GO:0004065	arylsulfatase activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0004705	JUN kinase activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0005344	oxygen carrier activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0008191	metalloendopeptidase inhibitor activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0031404	chloride ion binding	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0042043	neurexin family protein binding	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0042813	Wnt receptor activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0046030	inositol trisphosphate phosphatase activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0098821	BMP receptor activity	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:1990825	sequence-specific mRNA binding	2/2525	14/18639	0.142857142857143	1.05454031117397	0.583956191180787	0.952615402784819
GO:0015291	secondary active transmembrane transporter activity	38/2525	287/18639	0.132404181184669	0.977378824990513	0.58716956227644	0.953975093066498
GO:0008093	cytoskeletal anchor activity	3/2525	22/18639	0.136363636363636	1.00660666066607	0.588665415933622	0.953975093066498
GO:0008970	phospholipase A1 activity	3/2525	22/18639	0.136363636363636	1.00660666066607	0.588665415933622	0.953975093066498
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/2525	22/18639	0.136363636363636	1.00660666066607	0.588665415933622	0.953975093066498
GO:0140784	metal ion sensor activity	3/2525	22/18639	0.136363636363636	1.00660666066607	0.588665415933622	0.953975093066498
GO:0016860	intramolecular oxidoreductase activity	7/2525	53/18639	0.132075471698113	0.974952363160844	0.589536790058718	0.953975093066498
GO:0098631	cell adhesion mediator activity	10/2525	76/18639	0.131578947368421	0.971287128712871	0.590333573960216	0.953975093066498
GO:0016874	ligase activity	22/2525	167/18639	0.131736526946108	0.97245034683109	0.590696652053559	0.953975093066498
GO:0015215	nucleotide transmembrane transporter activity	4/2525	30/18639	0.133333333333333	0.984237623762376	0.594080376839197	0.957047190618756
GO:0031210	phosphatidylcholine binding	4/2525	30/18639	0.133333333333333	0.984237623762376	0.594080376839197	0.957047190618756
GO:0003689	DNA clamp loader activity	21/2525	160/18639	0.13125	0.968858910891089	0.597337390536157	0.961095776553817
GO:0042887	amide transmembrane transporter activity	5/2525	38/18639	0.131578947368421	0.971287128712871	0.599561801544245	0.963474934819857
GO:0016279	protein-lysine N-methyltransferase activity	9/2525	69/18639	0.130434782608696	0.962841153680585	0.601970846058495	0.965632814444
GO:0052689	carboxylic ester hydrolase activity	12/2525	92/18639	0.130434782608696	0.962841153680585	0.602399418298656	0.965632814444
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	6/2525	46/18639	0.130434782608696	0.962841153680585	0.604920761290775	0.967274286618418
GO:0030276	clathrin binding	6/2525	46/18639	0.130434782608696	0.962841153680585	0.604920761290775	0.967274286618418
GO:0140463	chromatin-protein adaptor activity	7/2525	54/18639	0.12962962962963	0.956897689768977	0.610099865094449	0.97047021031689
GO:0015179	L-amino acid transmembrane transporter activity	8/2525	62/18639	0.129032258064516	0.952488022995848	0.615086779723774	0.97047021031689
GO:0015294	solute:monoatomic cation symporter activity	15/2525	116/18639	0.129310344827586	0.954540798907477	0.618144519814503	0.97047021031689
GO:0016278	lysine N-methyltransferase activity	9/2525	70/18639	0.128571428571429	0.949086280056577	0.61988577714017	0.97047021031689
GO:0097110	scaffold protein binding	9/2525	70/18639	0.128571428571429	0.949086280056577	0.61988577714017	0.97047021031689
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2525	23/18639	0.130434782608696	0.962841153680585	0.619926330640704	0.97047021031689
GO:0003887	DNA-directed DNA polymerase activity	3/2525	23/18639	0.130434782608696	0.962841153680585	0.619926330640704	0.97047021031689
GO:0005283	amino acid:sodium symporter activity	3/2525	23/18639	0.130434782608696	0.962841153680585	0.619926330640704	0.97047021031689
GO:0043274	phospholipase binding	3/2525	23/18639	0.130434782608696	0.962841153680585	0.619926330640704	0.97047021031689
GO:0070325	lipoprotein particle receptor binding	4/2525	31/18639	0.129032258064516	0.952488022995848	0.62095264829994	0.97047021031689
GO:0004467	long-chain fatty acid-CoA ligase activity	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0004953	icosanoid receptor activity	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0005523	tropomyosin binding	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0031005	filamin binding	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0047372	monoacylglycerol lipase activity	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0051371	muscle alpha-actinin binding	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0061578	K63-linked deubiquitinase activity	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0141050	histone H3K deacetylase activity	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0141051	histone H4K deacetylase activity	2/2525	15/18639	0.133333333333333	0.984237623762376	0.622693347022215	0.97047021031689
GO:0000217	DNA secondary structure binding	5/2525	39/18639	0.128205128205128	0.946382330540746	0.62345697822614	0.970489657672497
GO:0061749	forked DNA-dependent helicase activity	6/2525	47/18639	0.127659574468085	0.942355171687381	0.626623325721454	0.973073722153989
GO:1990518	single-stranded 3'-5' DNA helicase activity	6/2525	47/18639	0.127659574468085	0.942355171687381	0.626623325721454	0.973073722153989
GO:0004620	phospholipase activity	14/2525	109/18639	0.128440366972477	0.948118811881188	0.627435117272672	0.973164671688226
GO:0004386	helicase activity	20/2525	155/18639	0.129032258064516	0.952488022995848	0.628450512831976	0.973570818439944
GO:0005319	lipid transporter activity	23/2525	178/18639	0.129213483146067	0.953825787073089	0.629927079185875	0.973789477577093
GO:0098632	cell-cell adhesion mediator activity	7/2525	55/18639	0.127272727272727	0.939499549954995	0.630099073726354	0.973789477577093
GO:0005507	copper ion binding	8/2525	63/18639	0.126984126984127	0.937369165487977	0.633712126660941	0.978203187151656
GO:0140299	molecular sensor activity	9/2525	71/18639	0.126760563380282	0.935718867661414	0.637371725109112	0.982678125108559
GO:0016835	carbon-oxygen lyase activity	10/2525	79/18639	0.126582278481013	0.934402807369345	0.641027599847975	0.986119481959028
GO:0008094	ATP-dependent activity, acting on DNA	27/2525	210/18639	0.128571428571429	0.949086280056577	0.645939511250875	0.986119481959028
GO:0015036	disulfide oxidoreductase activity	5/2525	40/18639	0.125	0.922722772277228	0.646475631376293	0.986119481959028
GO:0008378	galactosyltransferase activity	4/2525	32/18639	0.125	0.922722772277228	0.646673385081084	0.986119481959028
GO:0015106	bicarbonate transmembrane transporter activity	4/2525	32/18639	0.125	0.922722772277228	0.646673385081084	0.986119481959028
GO:0022884	macromolecule transmembrane transporter activity	4/2525	32/18639	0.125	0.922722772277228	0.646673385081084	0.986119481959028
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/2525	32/18639	0.125	0.922722772277228	0.646673385081084	0.986119481959028
GO:0009378	four-way junction helicase activity	6/2525	48/18639	0.125	0.922722772277228	0.647619030415783	0.986119481959028
GO:0036121	double-stranded DNA helicase activity	6/2525	48/18639	0.125	0.922722772277228	0.647619030415783	0.986119481959028
GO:0043138	3'-5' DNA helicase activity	6/2525	48/18639	0.125	0.922722772277228	0.647619030415783	0.986119481959028
GO:0004867	serine-type endopeptidase inhibitor activity	12/2525	95/18639	0.126315789473684	0.932435643564356	0.648225956988438	0.986119481959028
GO:0030552	cAMP binding	3/2525	24/18639	0.125	0.922722772277228	0.649526067451341	0.986119481959028
GO:0050699	WW domain binding	3/2525	24/18639	0.125	0.922722772277228	0.649526067451341	0.986119481959028
GO:0048306	calcium-dependent protein binding	10/2525	80/18639	0.125	0.922722772277228	0.65714566416454	0.988244749309652
GO:0004707	MAP kinase activity	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0005024	transforming growth factor beta receptor activity	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0008296	3'-5'-DNA exonuclease activity	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0019841	retinol binding	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0030275	LRR domain binding	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0043023	ribosomal large subunit binding	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0055102	lipase inhibitor activity	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2525	16/18639	0.125	0.922722772277228	0.6585748677675	0.988244749309652
GO:0015297	antiporter activity	17/2525	135/18639	0.125925925925926	0.929557755775578	0.665167767836866	0.996979995412101
GO:0008137	NADH dehydrogenase (ubiquinone) activity	5/2525	41/18639	0.121951219512195	0.900217338807051	0.668586552752073	0.997931839506774
GO:0061650	ubiquitin-like protein conjugating enzyme activity	5/2525	41/18639	0.121951219512195	0.900217338807051	0.668586552752073	0.997931839506774
GO:0160215	deacylase activity	8/2525	65/18639	0.123076923076923	0.908527037319117	0.669409412301423	0.997931839506774
GO:0003823	antigen binding	22/2525	174/18639	0.126436781609195	0.933328781153978	0.669901280294531	0.997931839506774
GO:0019239	deaminase activity	4/2525	33/18639	0.121212121212121	0.894761476147615	0.671209573166708	0.997931839506774
GO:0042923	neuropeptide binding	4/2525	33/18639	0.121212121212121	0.894761476147615	0.671209573166708	0.997931839506774
GO:0071889	14-3-3 protein binding	4/2525	33/18639	0.121212121212121	0.894761476147615	0.671209573166708	0.997931839506774
GO:0015101	organic cation transmembrane transporter activity	10/2525	81/18639	0.123456790123457	0.911331133113311	0.672845770875303	0.999149449661311
GO:0000030	mannosyltransferase activity	3/2525	25/18639	0.12	0.885813861386139	0.677441886922065	0.999149449661311
GO:0005537	D-mannose binding	3/2525	25/18639	0.12	0.885813861386139	0.677441886922065	0.999149449661311
GO:0015662	P-type ion transporter activity	3/2525	25/18639	0.12	0.885813861386139	0.677441886922065	0.999149449661311
GO:0042974	nuclear retinoic acid receptor binding	3/2525	25/18639	0.12	0.885813861386139	0.677441886922065	0.999149449661311
GO:0047617	fatty acyl-CoA hydrolase activity	3/2525	25/18639	0.12	0.885813861386139	0.677441886922065	0.999149449661311
GO:0140358	P-type transmembrane transporter activity	3/2525	25/18639	0.12	0.885813861386139	0.677441886922065	0.999149449661311
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0004549	tRNA-specific ribonuclease activity	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0015278	intracellularly gated calcium channel activity	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0030548	acetylcholine receptor regulator activity	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0032977	membrane insertase activity	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0048038	quinone binding	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0070402	NADPH binding	2/2525	17/18639	0.117647058823529	0.868444962143273	0.69166327008	0.999999999999999
GO:0015035	protein-disulfide reductase activity	4/2525	34/18639	0.117647058823529	0.868444962143273	0.694542425144188	0.999999999999999
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4/2525	34/18639	0.117647058823529	0.868444962143273	0.694542425144188	0.999999999999999
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	4/2525	34/18639	0.117647058823529	0.868444962143273	0.694542425144188	0.999999999999999
GO:0046982	protein heterodimerization activity	47/2525	369/18639	0.127371273712737	0.940226998309587	0.6994876649015	0.999999999999999
GO:0019003	GDP binding	9/2525	75/18639	0.12	0.885813861386139	0.702654065688928	0.999999999999999
GO:0015293	symporter activity	18/2525	146/18639	0.123287671232877	0.910082734300827	0.702789582592178	0.999999999999999
GO:0072341	modified amino acid binding	11/2525	91/18639	0.120879120879121	0.892303340224132	0.703630744014665	0.999999999999999
GO:0001637	G protein-coupled chemoattractant receptor activity	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0004950	chemokine receptor activity	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0005227	calcium-activated cation channel activity	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0015216	purine nucleotide transmembrane transporter activity	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0016289	acyl-CoA hydrolase activity	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0034237	protein kinase A regulatory subunit binding	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0043548	phosphatidylinositol 3-kinase binding	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0097602	cullin family protein binding	3/2525	26/18639	0.115384615384615	0.851744097486672	0.703673975375993	0.999999999999999
GO:0033218	amide binding	31/2525	247/18639	0.125506072874494	0.926458492003046	0.70489256625275	0.999999999999999
GO:0016229	steroid dehydrogenase activity	4/2525	35/18639	0.114285714285714	0.84363224893918	0.716665701233682	0.999999999999999
GO:0004843	cysteine-type deubiquitinase activity	13/2525	108/18639	0.12037037037037	0.888547854785478	0.718511881849826	0.999999999999999
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/2525	18/18639	0.111111111111111	0.82019801980198	0.722056532115804	0.999999999999999
GO:0008525	phosphatidylcholine transporter activity	2/2525	18/18639	0.111111111111111	0.82019801980198	0.722056532115804	0.999999999999999
GO:0017128	phospholipid scramblase activity	2/2525	18/18639	0.111111111111111	0.82019801980198	0.722056532115804	0.999999999999999
GO:0034185	apolipoprotein binding	2/2525	18/18639	0.111111111111111	0.82019801980198	0.722056532115804	0.999999999999999
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2525	18/18639	0.111111111111111	0.82019801980198	0.722056532115804	0.999999999999999
GO:0070064	proline-rich region binding	2/2525	18/18639	0.111111111111111	0.82019801980198	0.722056532115804	0.999999999999999
GO:0099602	neurotransmitter receptor regulator activity	2/2525	18/18639	0.111111111111111	0.82019801980198	0.722056532115804	0.999999999999999
GO:0031406	carboxylic acid binding	23/2525	187/18639	0.122994652406417	0.907919733149786	0.723031638143962	0.999999999999999
GO:0004364	glutathione transferase activity	3/2525	27/18639	0.111111111111111	0.82019801980198	0.728241513114214	0.999999999999999
GO:0005044	scavenger receptor activity	3/2525	27/18639	0.111111111111111	0.82019801980198	0.728241513114214	0.999999999999999
GO:0003954	NADH dehydrogenase activity	5/2525	44/18639	0.113636363636364	0.838838883888389	0.729297217021255	0.999999999999999
GO:0030547	signaling receptor inhibitor activity	5/2525	44/18639	0.113636363636364	0.838838883888389	0.729297217021255	0.999999999999999
GO:0015103	inorganic anion transmembrane transporter activity	20/2525	165/18639	0.121212121212121	0.894761476147615	0.737514840682239	0.999999999999999
GO:0045505	dynein intermediate chain binding	4/2525	36/18639	0.111111111111111	0.82019801980198	0.737584090301822	0.999999999999999
GO:0004864	protein phosphatase inhibitor activity	6/2525	53/18639	0.113207547169811	0.835673454137867	0.741257835161572	0.999999999999999
GO:0038064	collagen receptor activity	6/2525	53/18639	0.113207547169811	0.835673454137867	0.741257835161572	0.999999999999999
GO:0043177	organic acid binding	23/2525	189/18639	0.121693121693122	0.898312116925978	0.741669578937596	0.999999999999999
GO:0042562	hormone binding	11/2525	94/18639	0.117021276595745	0.863825574046767	0.743626080290916	0.999999999999999
GO:0016782	transferase activity, transferring sulphur-containing groups	8/2525	70/18639	0.114285714285714	0.84363224893918	0.748887194635321	0.999999999999999
GO:0003756	protein disulfide isomerase activity	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0016918	retinal binding	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0034987	immunoglobulin receptor binding	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0046527	glucosyltransferase activity	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0046624	sphingolipid transporter activity	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0070003	threonine-type peptidase activity	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:1990380	K48-linked deubiquitinase activity	2/2525	19/18639	0.105263157894737	0.777029702970297	0.749877345367581	0.999999999999999
GO:0051019	mitogen-activated protein kinase binding	3/2525	28/18639	0.107142857142857	0.790905233380481	0.751179134905778	0.999999999999999
GO:0051119	sugar transmembrane transporter activity	3/2525	28/18639	0.107142857142857	0.790905233380481	0.751179134905778	0.999999999999999
GO:0051537	2 iron, 2 sulfur cluster binding	3/2525	28/18639	0.107142857142857	0.790905233380481	0.751179134905778	0.999999999999999
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/2525	28/18639	0.107142857142857	0.790905233380481	0.751179134905778	0.999999999999999
GO:0017171	serine hydrolase activity	24/2525	198/18639	0.121212121212121	0.894761476147615	0.751945582129776	0.999999999999999
GO:0019783	ubiquitin-like protein peptidase activity	15/2525	127/18639	0.118110236220472	0.87186403679738	0.75413562872097	0.999999999999999
GO:0005253	monoatomic anion channel activity	12/2525	103/18639	0.116504854368932	0.860013457656445	0.755076347387467	0.999999999999999
GO:0030551	cyclic nucleotide binding	4/2525	37/18639	0.108108108108108	0.798030505753278	0.757311672832136	0.999999999999999
GO:0000182	rDNA binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0004955	prostaglandin receptor activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0005131	growth hormone receptor binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0005337	nucleoside transmembrane transporter activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0005381	iron ion transmembrane transporter activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0005522	profilin binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0008401	retinoic acid 4-hydroxylase activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0015203	polyamine transmembrane transporter activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0015643	toxic substance binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0031434	mitogen-activated protein kinase kinase binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0033204	ribonuclease P RNA binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0043295	glutathione binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0047429	nucleoside triphosphate diphosphatase activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0050815	phosphoserine residue binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0051864	histone H3K36 demethylase activity	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0070097	delta-catenin binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0070513	death domain binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0097177	mitochondrial ribosome binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0098505	G-rich strand telomeric DNA binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0099122	RNA polymerase II C-terminal domain binding	1/2525	10/18639	0.1	0.738178217821782	0.766845849190435	0.999999999999999
GO:0005416	amino acid:monoatomic cation symporter activity	3/2525	29/18639	0.103448275862069	0.763632639125982	0.772533782728045	0.999999999999999
GO:0035250	UDP-galactosyltransferase activity	3/2525	29/18639	0.103448275862069	0.763632639125982	0.772533782728045	0.999999999999999
GO:0000339	RNA cap binding	2/2525	20/18639	0.1	0.738178217821782	0.775264626031632	0.999999999999999
GO:0042288	MHC class I protein binding	2/2525	20/18639	0.1	0.738178217821782	0.775264626031632	0.999999999999999
GO:0061608	nuclear import signal receptor activity	2/2525	20/18639	0.1	0.738178217821782	0.775264626031632	0.999999999999999
GO:0140664	ATP-dependent DNA damage sensor activity	2/2525	20/18639	0.1	0.738178217821782	0.775264626031632	0.999999999999999
GO:0000146	microfilament motor activity	4/2525	38/18639	0.105263157894737	0.777029702970297	0.775870481218946	0.999999999999999
GO:0042162	telomeric DNA binding	4/2525	38/18639	0.105263157894737	0.777029702970297	0.775870481218946	0.999999999999999
GO:0005504	fatty acid binding	5/2525	47/18639	0.106382978723404	0.785295976406151	0.781524969244057	0.999999999999999
GO:0140359	ABC-type transporter activity	5/2525	47/18639	0.106382978723404	0.785295976406151	0.781524969244057	0.999999999999999
GO:0008236	serine-type peptidase activity	23/2525	194/18639	0.118556701030928	0.875159742778402	0.784731749721848	0.999999999999999
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	14/2525	122/18639	0.114754098360656	0.847089758156144	0.785889806291875	0.999999999999999
GO:0030170	pyridoxal phosphate binding	6/2525	56/18639	0.107142857142857	0.790905233380481	0.788123270699651	0.999999999999999
GO:0022839	monoatomic ion-gated channel activity	3/2525	30/18639	0.1	0.738178217821782	0.792361938937917	0.999999999999999
GO:0048019	receptor antagonist activity	3/2525	30/18639	0.1	0.738178217821782	0.792361938937917	0.999999999999999
GO:0008188	neuropeptide receptor activity	5/2525	48/18639	0.104166666666667	0.768935643564356	0.797095427247344	0.999999999999999
GO:0016879	ligase activity, forming carbon-nitrogen bonds	5/2525	48/18639	0.104166666666667	0.768935643564356	0.797095427247344	0.999999999999999
GO:0101005	deubiquitinase activity	13/2525	115/18639	0.11304347826087	0.834462333189841	0.797362514335018	0.999999999999999
GO:0005123	death receptor binding	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0005248	voltage-gated sodium channel activity	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0009975	cyclase activity	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0010314	phosphatidylinositol-5-phosphate binding	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0015125	bile acid transmembrane transporter activity	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0035613	RNA stem-loop binding	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0051428	peptide hormone receptor binding	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0061891	calcium ion sensor activity	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:1904047	S-adenosyl-L-methionine binding	2/2525	21/18639	0.0952380952380952	0.703026874115983	0.798366871308447	0.999999999999999
GO:0001851	complement component C3b binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0002162	dystroglycan binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0004016	adenylate cyclase activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0004954	prostanoid receptor activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0008046	axon guidance receptor activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0008432	JUN kinase binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0008503	benzodiazepine receptor activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0019107	myristoyltransferase activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0019215	intermediate filament binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0032050	clathrin heavy chain binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0032404	mismatch repair complex binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0035252	UDP-xylosyltransferase activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0042285	xylosyltransferase activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0043522	leucine zipper domain binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0045294	alpha-catenin binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0047676	arachidonate-CoA ligase activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0048407	platelet-derived growth factor binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0070697	activin receptor binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0070990	snRNP binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0097493	structural molecule activity conferring elasticity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0140537	transcription regulator activator activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:1900750	oligopeptide binding	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:1990948	ubiquitin ligase inhibitor activity	1/2525	11/18639	0.0909090909090909	0.671071107110711	0.79844787993788	0.999999999999999
GO:0031491	nucleosome binding	8/2525	74/18639	0.108108108108108	0.798030505753278	0.802063725209871	0.999999999999999
GO:0070279	vitamin B6 binding	6/2525	57/18639	0.105263157894737	0.777029702970297	0.802220621736364	0.999999999999999
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	15/2525	132/18639	0.113636363636364	0.838838883888389	0.803932423857568	0.999999999999999
GO:0015144	carbohydrate transmembrane transporter activity	4/2525	40/18639	0.1	0.738178217821782	0.809601782375153	0.999999999999999
GO:0008509	monoatomic anion transmembrane transporter activity	17/2525	149/18639	0.114093959731544	0.842216758588611	0.810541752616708	0.999999999999999
GO:0005452	solute:inorganic anion antiporter activity	3/2525	31/18639	0.0967741935483871	0.714366017246886	0.8107272200777	0.999999999999999
GO:0047499	calcium-independent phospholipase A2 activity	3/2525	31/18639	0.0967741935483871	0.714366017246886	0.8107272200777	0.999999999999999
GO:0070273	phosphatidylinositol-4-phosphate binding	3/2525	31/18639	0.0967741935483871	0.714366017246886	0.8107272200777	0.999999999999999
GO:0017116	single-stranded DNA helicase activity	6/2525	58/18639	0.103448275862069	0.763632639125982	0.81557867681557	0.999999999999999
GO:0004407	histone deacetylase activity	2/2525	22/18639	0.0909090909090909	0.671071107110711	0.819337016845929	0.999999999999999
GO:0015377	chloride:monoatomic cation symporter activity	2/2525	22/18639	0.0909090909090909	0.671071107110711	0.819337016845929	0.999999999999999
GO:0033558	protein lysine deacetylase activity	2/2525	22/18639	0.0909090909090909	0.671071107110711	0.819337016845929	0.999999999999999
GO:0050321	tau-protein kinase activity	2/2525	22/18639	0.0909090909090909	0.671071107110711	0.819337016845929	0.999999999999999
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/2525	41/18639	0.0975609756097561	0.720173871045641	0.824846672064135	0.999999999999999
GO:0140318	protein transporter activity	4/2525	41/18639	0.0975609756097561	0.720173871045641	0.824846672064135	0.999999999999999
GO:0003995	acyl-CoA dehydrogenase activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0004126	cytidine deaminase activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0004526	ribonuclease P activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0004859	phospholipase inhibitor activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0005078	MAP-kinase scaffold activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0008504	monoamine transmembrane transporter activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0015132	prostaglandin transmembrane transporter activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0015166	polyol transmembrane transporter activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0017166	vinculin binding	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0035251	UDP-glucosyltransferase activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0042301	phosphate ion binding	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0043047	single-stranded telomeric DNA binding	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0097371	MDM2/MDM4 family protein binding	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0140900	chloride:bicarbonate antiporter activity	1/2525	12/18639	0.0833333333333333	0.615148514851485	0.825767994988172	0.999999999999999
GO:0047498	calcium-dependent phospholipase A2 activity	3/2525	32/18639	0.09375	0.692042079207921	0.827698306456661	0.999999999999999
GO:0051059	NF-kappaB binding	3/2525	32/18639	0.09375	0.692042079207921	0.827698306456661	0.999999999999999
GO:0003777	microtubule motor activity	7/2525	68/18639	0.102941176470588	0.759889341875364	0.831842070413643	0.999999999999999
GO:0005548	phospholipid transporter activity	7/2525	68/18639	0.102941176470588	0.759889341875364	0.831842070413643	0.999999999999999
GO:0005212	structural constituent of eye lens	2/2525	23/18639	0.0869565217391304	0.641894102453724	0.838328510770236	0.999999999999999
GO:0016493	C-C chemokine receptor activity	2/2525	23/18639	0.0869565217391304	0.641894102453724	0.838328510770236	0.999999999999999
GO:0031681	G-protein beta-subunit binding	2/2525	23/18639	0.0869565217391304	0.641894102453724	0.838328510770236	0.999999999999999
GO:0043021	ribonucleoprotein complex binding	20/2525	177/18639	0.112994350282486	0.834099681154556	0.83855569296456	0.999999999999999
GO:0005048	signal sequence binding	5/2525	51/18639	0.0980392156862745	0.723704135119394	0.838586875109113	0.999999999999999
GO:0031492	nucleosomal DNA binding	4/2525	42/18639	0.0952380952380952	0.703026874115983	0.839065484150211	0.999999999999999
GO:0035198	miRNA binding	4/2525	42/18639	0.0952380952380952	0.703026874115983	0.839065484150211	0.999999999999999
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	6/2525	60/18639	0.1	0.738178217821782	0.840149836871887	0.999999999999999
GO:0016209	antioxidant activity	9/2525	86/18639	0.104651162790698	0.772512088418144	0.84050119901224	0.999999999999999
GO:0003774	cytoskeletal motor activity	17/2525	153/18639	0.111111111111111	0.82019801980198	0.842298617278409	0.999999999999999
GO:0005200	structural constituent of cytoskeleton	12/2525	112/18639	0.107142857142857	0.790905233380481	0.846129353750158	0.999999999999999
GO:0008083	growth factor activity	18/2525	162/18639	0.111111111111111	0.82019801980198	0.847986697554183	0.999999999999999
GO:0004993	G protein-coupled serotonin receptor activity	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0005172	vascular endothelial growth factor receptor binding	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0005542	folic acid binding	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0032396	inhibitory MHC class I receptor activity	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0039706	co-receptor binding	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0051011	microtubule minus-end binding	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0070700	BMP receptor binding	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:1901338	catecholamine binding	1/2525	13/18639	0.0769230769230769	0.567829398324448	0.849386173581337	0.999999999999999
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/2525	43/18639	0.0930232558139535	0.686677411927239	0.852302287122322	0.999999999999999
GO:0004806	triacylglycerol lipase activity	2/2525	24/18639	0.0833333333333333	0.615148514851485	0.855492369253772	0.999999999999999
GO:0015149	hexose transmembrane transporter activity	2/2525	24/18639	0.0833333333333333	0.615148514851485	0.855492369253772	0.999999999999999
GO:0048027	mRNA 5'-UTR binding	2/2525	24/18639	0.0833333333333333	0.615148514851485	0.855492369253772	0.999999999999999
GO:0055056	D-glucose transmembrane transporter activity	2/2525	24/18639	0.0833333333333333	0.615148514851485	0.855492369253772	0.999999999999999
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2525	24/18639	0.0833333333333333	0.615148514851485	0.855492369253772	0.999999999999999
GO:0140612	DNA damage sensor activity	2/2525	24/18639	0.0833333333333333	0.615148514851485	0.855492369253772	0.999999999999999
GO:0015370	solute:sodium symporter activity	8/2525	79/18639	0.10126582278481	0.747522245895476	0.85599848550611	0.999999999999999
GO:0016651	oxidoreductase activity, acting on NAD(P)H	9/2525	88/18639	0.102272727272727	0.75495499549955	0.859152793805671	0.999999999999999
GO:0008331	high voltage-gated calcium channel activity	1/2525	14/18639	0.0714285714285714	0.527270155586987	0.869803864535225	0.999999999999999
GO:0008559	ABC-type xenobiotic transporter activity	1/2525	14/18639	0.0714285714285714	0.527270155586987	0.869803864535225	0.999999999999999
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/2525	14/18639	0.0714285714285714	0.527270155586987	0.869803864535225	0.999999999999999
GO:0032036	myosin heavy chain binding	1/2525	14/18639	0.0714285714285714	0.527270155586987	0.869803864535225	0.999999999999999
GO:0043176	amine binding	1/2525	14/18639	0.0714285714285714	0.527270155586987	0.869803864535225	0.999999999999999
GO:0098847	sequence-specific single stranded DNA binding	1/2525	14/18639	0.0714285714285714	0.527270155586987	0.869803864535225	0.999999999999999
GO:1901474	azole transmembrane transporter activity	1/2525	14/18639	0.0714285714285714	0.527270155586987	0.869803864535225	0.999999999999999
GO:0004623	phospholipase A2 activity	3/2525	35/18639	0.0857142857142857	0.632724186704385	0.870974071663366	0.999999999999999
GO:0005343	organic acid:sodium symporter activity	3/2525	35/18639	0.0857142857142857	0.632724186704385	0.870974071663366	0.999999999999999
GO:0061631	ubiquitin conjugating enzyme activity	3/2525	35/18639	0.0857142857142857	0.632724186704385	0.870974071663366	0.999999999999999
GO:0001848	complement binding	2/2525	25/18639	0.08	0.590542574257426	0.870975019891312	0.999999999999999
GO:0005251	delayed rectifier potassium channel activity	2/2525	25/18639	0.08	0.590542574257426	0.870975019891312	0.999999999999999
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/2525	25/18639	0.08	0.590542574257426	0.870975019891312	0.999999999999999
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/2525	36/18639	0.0833333333333333	0.615148514851485	0.883100433605324	0.999999999999999
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/2525	36/18639	0.0833333333333333	0.615148514851485	0.883100433605324	0.999999999999999
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/2525	36/18639	0.0833333333333333	0.615148514851485	0.883100433605324	0.999999999999999
GO:0005112	Notch binding	2/2525	26/18639	0.0769230769230769	0.567829398324448	0.884916773600922	0.999999999999999
GO:0015145	monosaccharide transmembrane transporter activity	2/2525	26/18639	0.0769230769230769	0.567829398324448	0.884916773600922	0.999999999999999
GO:0050681	nuclear androgen receptor binding	2/2525	26/18639	0.0769230769230769	0.567829398324448	0.884916773600922	0.999999999999999
GO:0050750	low-density lipoprotein particle receptor binding	2/2525	26/18639	0.0769230769230769	0.567829398324448	0.884916773600922	0.999999999999999
GO:0051139	metal cation:proton antiporter activity	2/2525	26/18639	0.0769230769230769	0.567829398324448	0.884916773600922	0.999999999999999
GO:0004089	carbonate dehydratase activity	1/2525	15/18639	0.0666666666666667	0.492118811881188	0.887454615786154	0.999999999999999
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/2525	15/18639	0.0666666666666667	0.492118811881188	0.887454615786154	0.999999999999999
GO:0008242	omega peptidase activity	1/2525	15/18639	0.0666666666666667	0.492118811881188	0.887454615786154	0.999999999999999
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/2525	15/18639	0.0666666666666667	0.492118811881188	0.887454615786154	0.999999999999999
GO:0034483	heparan sulfate sulfotransferase activity	1/2525	15/18639	0.0666666666666667	0.492118811881188	0.887454615786154	0.999999999999999
GO:0045504	dynein heavy chain binding	1/2525	15/18639	0.0666666666666667	0.492118811881188	0.887454615786154	0.999999999999999
GO:0003678	DNA helicase activity	7/2525	74/18639	0.0945945945945946	0.698276692534118	0.889578826226139	0.999999999999999
GO:0005254	chloride channel activity	8/2525	83/18639	0.0963855421686747	0.711497077418585	0.890050474477662	0.999999999999999
GO:0008135	translation factor activity, RNA binding	8/2525	83/18639	0.0963855421686747	0.711497077418585	0.890050474477662	0.999999999999999
GO:0046906	tetrapyrrole binding	16/2525	152/18639	0.105263157894737	0.777029702970297	0.890306768511367	0.999999999999999
GO:0022829	wide pore channel activity	3/2525	37/18639	0.0810810810810811	0.598522879314959	0.894199441908841	0.999999999999999
GO:0042805	actinin binding	3/2525	37/18639	0.0810810810810811	0.598522879314959	0.894199441908841	0.999999999999999
GO:0180051	translation factor activity	8/2525	84/18639	0.0952380952380952	0.703026874115983	0.897427650800536	0.999999999999999
GO:0005385	zinc ion transmembrane transporter activity	2/2525	27/18639	0.0740740740740741	0.546798679867987	0.897450794439859	0.999999999999999
GO:0008320	protein transmembrane transporter activity	2/2525	27/18639	0.0740740740740741	0.546798679867987	0.897450794439859	0.999999999999999
GO:0000062	fatty-acyl-CoA binding	1/2525	16/18639	0.0625	0.461361386138614	0.902713265654064	0.999999999999999
GO:0015385	sodium:proton antiporter activity	1/2525	16/18639	0.0625	0.461361386138614	0.902713265654064	0.999999999999999
GO:0015562	efflux transmembrane transporter activity	1/2525	16/18639	0.0625	0.461361386138614	0.902713265654064	0.999999999999999
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/2525	16/18639	0.0625	0.461361386138614	0.902713265654064	0.999999999999999
GO:0016853	isomerase activity	19/2525	180/18639	0.105555555555556	0.779188118811881	0.904652254335456	0.999999999999999
GO:0016500	protein-hormone receptor activity	6/2525	67/18639	0.0895522388059701	0.661055120437417	0.905986999809041	0.999999999999999
GO:0015108	chloride transmembrane transporter activity	12/2525	121/18639	0.0991735537190083	0.732077571393503	0.908527399645281	0.999999999999999
GO:0008527	taste receptor activity	2/2525	28/18639	0.0714285714285714	0.527270155586987	0.908702460557865	0.999999999999999
GO:0051393	alpha-actinin binding	2/2525	28/18639	0.0714285714285714	0.527270155586987	0.908702460557865	0.999999999999999
GO:0141052	histone H3 demethylase activity	2/2525	28/18639	0.0714285714285714	0.527270155586987	0.908702460557865	0.999999999999999
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/2525	58/18639	0.0862068965517241	0.636360532604985	0.908752611223839	0.999999999999999
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	19/2525	181/18639	0.104972375690608	0.774883212078114	0.909317861292526	0.999999999999999
GO:0140767	enzyme-substrate adaptor activity	14/2525	139/18639	0.100719424460432	0.743488852482371	0.912109545614462	0.999999999999999
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/2525	39/18639	0.0769230769230769	0.567829398324448	0.913596320668558	0.999999999999999
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/2525	17/18639	0.0588235294117647	0.434222481071637	0.915903890377443	0.999999999999999
GO:0009881	photoreceptor activity	1/2525	17/18639	0.0588235294117647	0.434222481071637	0.915903890377443	0.999999999999999
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2525	17/18639	0.0588235294117647	0.434222481071637	0.915903890377443	0.999999999999999
GO:0036041	long-chain fatty acid binding	1/2525	17/18639	0.0588235294117647	0.434222481071637	0.915903890377443	0.999999999999999
GO:0045236	CXCR chemokine receptor binding	1/2525	17/18639	0.0588235294117647	0.434222481071637	0.915903890377443	0.999999999999999
GO:0070492	oligosaccharide binding	1/2525	17/18639	0.0588235294117647	0.434222481071637	0.915903890377443	0.999999999999999
GO:1901567	fatty acid derivative binding	1/2525	17/18639	0.0588235294117647	0.434222481071637	0.915903890377443	0.999999999999999
GO:0003785	actin monomer binding	2/2525	29/18639	0.0689655172413793	0.509088426083988	0.918789029285999	0.999999999999999
GO:0099604	ligand-gated calcium channel activity	2/2525	29/18639	0.0689655172413793	0.509088426083988	0.918789029285999	0.999999999999999
GO:0005006	epidermal growth factor receptor activity	4/2525	50/18639	0.08	0.590542574257426	0.921359003972581	0.999999999999999
GO:0032451	demethylase activity	3/2525	40/18639	0.075	0.553633663366337	0.922028310259915	0.999999999999999
GO:0019842	vitamin binding	15/2525	150/18639	0.1	0.738178217821782	0.923249183100024	0.999999999999999
GO:0033293	monocarboxylic acid binding	7/2525	79/18639	0.0886075949367089	0.654081965158541	0.924009799610965	0.999999999999999
GO:0003746	translation elongation factor activity	1/2525	18/18639	0.0555555555555556	0.41009900990099	0.92730667615754	0.999999999999999
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/2525	18/18639	0.0555555555555556	0.41009900990099	0.92730667615754	0.999999999999999
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/2525	18/18639	0.0555555555555556	0.41009900990099	0.92730667615754	0.999999999999999
GO:0022851	GABA-gated chloride ion channel activity	1/2525	18/18639	0.0555555555555556	0.41009900990099	0.92730667615754	0.999999999999999
GO:1990381	ubiquitin-specific protease binding	1/2525	18/18639	0.0555555555555556	0.41009900990099	0.92730667615754	0.999999999999999
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/2525	30/18639	0.0666666666666667	0.492118811881188	0.927819535739434	0.999999999999999
GO:0032452	histone demethylase activity	2/2525	30/18639	0.0666666666666667	0.492118811881188	0.927819535739434	0.999999999999999
GO:0033612	receptor serine/threonine kinase binding	2/2525	30/18639	0.0666666666666667	0.492118811881188	0.927819535739434	0.999999999999999
GO:0098918	structural constituent of synapse	2/2525	30/18639	0.0666666666666667	0.492118811881188	0.927819535739434	0.999999999999999
GO:0005272	sodium channel activity	4/2525	51/18639	0.0784313725490196	0.578963308095515	0.928403440471599	0.999999999999999
GO:0140828	metal cation:monoatomic cation antiporter activity	3/2525	41/18639	0.0731707317073171	0.540130403284231	0.929700544854318	0.999999999999999
GO:0017147	Wnt-protein binding	2/2525	31/18639	0.0645161290322581	0.476244011497924	0.935894867854036	0.999999999999999
GO:0140457	protein demethylase activity	2/2525	31/18639	0.0645161290322581	0.476244011497924	0.935894867854036	0.999999999999999
GO:0016859	cis-trans isomerase activity	3/2525	42/18639	0.0714285714285714	0.527270155586987	0.936672472600788	0.999999999999999
GO:0004890	GABA-A receptor activity	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0030506	ankyrin binding	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0031420	alkali metal ion binding	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0042577	lipid phosphatase activity	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0099589	serotonin receptor activity	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0120227	acyl-CoA binding	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0141147	intracellularly calcium-gated channel activity	1/2525	19/18639	0.0526315789473684	0.388514851485149	0.937163861201426	0.999999999999999
GO:0019838	growth factor binding	13/2525	136/18639	0.0955882352941176	0.705611531741409	0.937624856474129	0.999999999999999
GO:0008146	sulfotransferase activity	4/2525	53/18639	0.0754716981132075	0.557115636091911	0.940807524185222	0.999999999999999
GO:0017046	peptide hormone binding	4/2525	53/18639	0.0754716981132075	0.557115636091911	0.940807524185222	0.999999999999999
GO:0005245	voltage-gated calcium channel activity	3/2525	43/18639	0.0697674418604651	0.515008058945429	0.943000236511673	0.999999999999999
GO:0005326	neurotransmitter transmembrane transporter activity	1/2525	20/18639	0.05	0.369089108910891	0.945684873578784	0.999999999999999
GO:0043024	ribosomal small subunit binding	1/2525	20/18639	0.05	0.369089108910891	0.945684873578784	0.999999999999999
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/2525	44/18639	0.0681818181818182	0.503303330333033	0.948736634734545	0.999999999999999
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	11/2525	122/18639	0.0901639344262295	0.665570524265541	0.951780296843481	0.999999999999999
GO:0001846	opsonin binding	1/2525	21/18639	0.0476190476190476	0.351513437057991	0.953050773692301	0.999999999999999
GO:0004252	serine-type endopeptidase activity	17/2525	176/18639	0.0965909090909091	0.71301305130513	0.953262295190126	0.999999999999999
GO:0015020	glucuronosyltransferase activity	2/2525	34/18639	0.0588235294117647	0.434222481071637	0.955281434097548	0.999999999999999
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/2525	34/18639	0.0588235294117647	0.434222481071637	0.955281434097548	0.999999999999999
GO:0016831	carboxy-lyase activity	2/2525	34/18639	0.0588235294117647	0.434222481071637	0.955281434097548	0.999999999999999
GO:0019825	oxygen binding	2/2525	34/18639	0.0588235294117647	0.434222481071637	0.955281434097548	0.999999999999999
GO:0051427	hormone receptor binding	2/2525	34/18639	0.0588235294117647	0.434222481071637	0.955281434097548	0.999999999999999
GO:0005201	extracellular matrix structural constituent	16/2525	168/18639	0.0952380952380952	0.703026874115983	0.95542456064536	0.999999999999999
GO:0020037	heme binding	13/2525	142/18639	0.0915492957746479	0.675796959977688	0.957494260416977	0.999999999999999
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/2525	46/18639	0.0652173913043478	0.481420576840293	0.958629905449889	0.999999999999999
GO:0016881	acid-amino acid ligase activity	1/2525	22/18639	0.0454545454545455	0.335535553555356	0.95941809544689	0.999999999999999
GO:0140517	protein-RNA adaptor activity	1/2525	22/18639	0.0454545454545455	0.335535553555356	0.95941809544689	0.999999999999999
GO:0004497	monooxygenase activity	9/2525	106/18639	0.0849056603773585	0.6267550906034	0.959654344315382	0.999999999999999
GO:0019199	transmembrane receptor protein kinase activity	6/2525	78/18639	0.0769230769230769	0.567829398324448	0.962387810304834	0.999999999999999
GO:0099095	ligand-gated monoatomic anion channel activity	3/2525	47/18639	0.0638297872340425	0.471177585843691	0.962875936668862	0.999999999999999
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2525	23/18639	0.0434782608695652	0.320947051226862	0.964922167477647	0.999999999999999
GO:0016917	GABA receptor activity	1/2525	23/18639	0.0434782608695652	0.320947051226862	0.964922167477647	0.999999999999999
GO:0017134	fibroblast growth factor binding	1/2525	23/18639	0.0434782608695652	0.320947051226862	0.964922167477647	0.999999999999999
GO:0099186	structural constituent of postsynapse	1/2525	23/18639	0.0434782608695652	0.320947051226862	0.964922167477647	0.999999999999999
GO:0004190	aspartic-type endopeptidase activity	2/2525	36/18639	0.0555555555555556	0.41009900990099	0.964937473427092	0.999999999999999
GO:0030280	structural constituent of skin epidermis	2/2525	37/18639	0.0540540540540541	0.399015252876639	0.968979646656706	0.999999999999999
GO:0070001	aspartic-type peptidase activity	2/2525	37/18639	0.0540540540540541	0.399015252876639	0.968979646656706	0.999999999999999
GO:0015085	calcium ion transmembrane transporter activity	13/2525	147/18639	0.0884353741496599	0.652810668821984	0.969556067658928	0.999999999999999
GO:0005540	hyaluronic acid binding	1/2525	24/18639	0.0416666666666667	0.307574257425743	0.969679984791729	0.999999999999999
GO:0050431	transforming growth factor beta binding	1/2525	24/18639	0.0416666666666667	0.307574257425743	0.969679984791729	0.999999999999999
GO:0005004	GPI-linked ephrin receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0005008	hepatocyte growth factor receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0005009	insulin receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0005011	macrophage colony-stimulating factor receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0005020	stem cell factor receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0008288	boss receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0036332	placental growth factor receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0038062	protein tyrosine kinase collagen receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0060175	brain-derived neurotrophic factor receptor activity	3/2525	49/18639	0.0612244897959184	0.451945847645989	0.970166334771724	0.999999999999999
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/2525	60/18639	0.0666666666666667	0.492118811881188	0.970316739660049	0.999999999999999
GO:0003735	structural constituent of ribosome	16/2525	175/18639	0.0914285714285714	0.674905799151344	0.971071338981425	0.999999999999999
GO:0022832	voltage-gated channel activity	16/2525	175/18639	0.0914285714285714	0.674905799151344	0.971071338981425	0.999999999999999
GO:0008237	metallopeptidase activity	17/2525	184/18639	0.0923913043478261	0.682012483857081	0.971122780009436	0.999999999999999
GO:0005501	retinoid binding	2/2525	38/18639	0.0526315789473684	0.388514851485149	0.972570631234652	0.999999999999999
GO:0019840	isoprenoid binding	2/2525	38/18639	0.0526315789473684	0.388514851485149	0.972570631234652	0.999999999999999
GO:0005007	fibroblast growth factor receptor activity	3/2525	50/18639	0.06	0.442906930693069	0.973281696312095	0.999999999999999
GO:0005017	platelet-derived growth factor receptor activity	3/2525	50/18639	0.06	0.442906930693069	0.973281696312095	0.999999999999999
GO:0005019	platelet-derived growth factor beta-receptor activity	3/2525	50/18639	0.06	0.442906930693069	0.973281696312095	0.999999999999999
GO:0008483	transaminase activity	1/2525	25/18639	0.04	0.295271287128713	0.973792691662579	0.999999999999999
GO:0015271	outward rectifier potassium channel activity	1/2525	25/18639	0.04	0.295271287128713	0.973792691662579	0.999999999999999
GO:0015171	amino acid transmembrane transporter activity	8/2525	102/18639	0.0784313725490196	0.578963308095515	0.973943841761766	0.999999999999999
GO:0005262	calcium channel activity	11/2525	131/18639	0.083969465648855	0.619844305041191	0.974574913129512	0.999999999999999
GO:0003743	translation initiation factor activity	3/2525	51/18639	0.0588235294117647	0.434222481071637	0.976086587302126	0.999999999999999
GO:0005010	insulin-like growth factor receptor activity	3/2525	51/18639	0.0588235294117647	0.434222481071637	0.976086587302126	0.999999999999999
GO:0005021	vascular endothelial growth factor receptor activity	3/2525	51/18639	0.0588235294117647	0.434222481071637	0.976086587302126	0.999999999999999
GO:0005030	neurotrophin receptor activity	3/2525	51/18639	0.0588235294117647	0.434222481071637	0.976086587302126	0.999999999999999
GO:0120014	phospholipid transfer activity	1/2525	26/18639	0.0384615384615385	0.283914699162224	0.977347728385045	0.999999999999999
GO:1901682	sulfur compound transmembrane transporter activity	4/2525	63/18639	0.0634920634920635	0.468684582743989	0.978144204410177	0.999999999999999
GO:0071855	neuropeptide receptor binding	2/2525	40/18639	0.05	0.369089108910891	0.978586332939786	0.999999999999999
GO:0005104	fibroblast growth factor receptor binding	1/2525	27/18639	0.037037037037037	0.273399339933993	0.980420687382937	0.999999999999999
GO:0008395	steroid hydroxylase activity	1/2525	27/18639	0.037037037037037	0.273399339933993	0.980420687382937	0.999999999999999
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/2525	27/18639	0.037037037037037	0.273399339933993	0.980420687382937	0.999999999999999
GO:0005003	ephrin receptor activity	3/2525	53/18639	0.0566037735849057	0.417836727068933	0.980878006268644	0.999999999999999
GO:0005005	transmembrane-ephrin receptor activity	3/2525	53/18639	0.0566037735849057	0.417836727068933	0.980878006268644	0.999999999999999
GO:0004812	aminoacyl-tRNA ligase activity	2/2525	41/18639	0.0487804878048781	0.360086935522821	0.981093296431348	0.999999999999999
GO:0008227	G protein-coupled amine receptor activity	2/2525	41/18639	0.0487804878048781	0.360086935522821	0.981093296431348	0.999999999999999
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/2525	41/18639	0.0487804878048781	0.360086935522821	0.981093296431348	0.999999999999999
GO:0005244	voltage-gated monoatomic ion channel activity	15/2525	173/18639	0.0867052023121387	0.640038917186516	0.981854068030571	0.999999999999999
GO:0015081	sodium ion transmembrane transporter activity	14/2525	164/18639	0.0853658536585366	0.630152137164936	0.982173416812592	0.999999999999999
GO:0019843	rRNA binding	4/2525	65/18639	0.0615384615384615	0.454263518659558	0.982233461914814	0.999999999999999
GO:0017069	snRNA binding	3/2525	54/18639	0.0555555555555556	0.41009900990099	0.982915251963342	0.999999999999999
GO:0005242	inward rectifier potassium channel activity	1/2525	28/18639	0.0357142857142857	0.263635077793494	0.983076918006088	0.999999999999999
GO:0005249	voltage-gated potassium channel activity	7/2525	98/18639	0.0714285714285714	0.527270155586987	0.984331321015985	0.999999999999999
GO:0004175	endopeptidase activity	41/2525	405/18639	0.101234567901235	0.747291529152915	0.985249965389903	0.999999999999999
GO:0170055	lipid transmembrane transporter activity	3/2525	56/18639	0.0535714285714286	0.39545261669024	0.986383769368438	0.999999999999999
GO:0016769	transferase activity, transferring nitrogenous groups	1/2525	30/18639	0.0333333333333333	0.246059405940594	0.987357513283267	0.999999999999999
GO:0000049	tRNA binding	5/2525	80/18639	0.0625	0.461361386138614	0.988212855213056	0.999999999999999
GO:0008528	G protein-coupled peptide receptor activity	9/2525	122/18639	0.0737704918032787	0.544557701671807	0.988741933302952	0.999999999999999
GO:0005179	hormone activity	10/2525	132/18639	0.0757575757575758	0.559225922592259	0.988816602938911	0.999999999999999
GO:0005184	neuropeptide hormone activity	1/2525	31/18639	0.032258064516129	0.238122005748962	0.989072934797574	0.999999999999999
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/2525	31/18639	0.032258064516129	0.238122005748962	0.989072934797574	0.999999999999999
GO:0072349	modified amino acid transmembrane transporter activity	1/2525	31/18639	0.032258064516129	0.238122005748962	0.989072934797574	0.999999999999999
GO:0008028	monocarboxylic acid transmembrane transporter activity	4/2525	70/18639	0.0571428571428571	0.42181612446959	0.989518683948978	0.999999999999999
GO:0022843	voltage-gated monoatomic cation channel activity	11/2525	143/18639	0.0769230769230769	0.567829398324448	0.989832578496758	0.999999999999999
GO:0005267	potassium channel activity	9/2525	124/18639	0.0725806451612903	0.535774512935165	0.990489335684122	0.999999999999999
GO:0030515	snoRNA binding	1/2525	32/18639	0.03125	0.230680693069307	0.990555675534683	0.999999999999999
GO:0042910	xenobiotic transmembrane transporter activity	1/2525	32/18639	0.03125	0.230680693069307	0.990555675534683	0.999999999999999
GO:0160041	neuropeptide activity	1/2525	32/18639	0.03125	0.230680693069307	0.990555675534683	0.999999999999999
GO:0090482	vitamin transmembrane transporter activity	1/2525	34/18639	0.0294117647058824	0.217111240535818	0.992945038719552	0.999999999999999
GO:0048029	monosaccharide binding	4/2525	74/18639	0.0540540540540541	0.399015252876639	0.993191462402055	0.999999999999999
GO:0001653	peptide receptor activity	9/2525	128/18639	0.0703125	0.519031559405941	0.993249663220115	0.999999999999999
GO:0046873	metal ion transmembrane transporter activity	44/2525	450/18639	0.0977777777777778	0.721774257425743	0.99425622905302	0.999999999999999
GO:0004222	metalloendopeptidase activity	7/2525	110/18639	0.0636363636363636	0.469749774977498	0.994792769067919	0.999999999999999
GO:0008514	organic anion transmembrane transporter activity	23/2525	269/18639	0.0855018587360595	0.631156097022342	0.995851763144779	0.999999999999999
GO:0015079	potassium ion transmembrane transporter activity	11/2525	160/18639	0.06875	0.507497524752475	0.997504666310293	0.999999999999999
GO:0008307	structural constituent of muscle	1/2525	42/18639	0.0238095238095238	0.175756718528996	0.997803946419696	0.999999999999999
GO:0046943	carboxylic acid transmembrane transporter activity	13/2525	188/18639	0.0691489361702128	0.510442384663998	0.998686079091284	0.999999999999999
GO:0005342	organic acid transmembrane transporter activity	13/2525	189/18639	0.0687830687830688	0.507741631305988	0.998792383843356	0.999999999999999
GO:0005216	monoatomic ion channel activity	39/2525	448/18639	0.0870535714285714	0.642610502121641	0.999463269589874	0.999999999999999
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/2525	53/18639	0.0188679245283019	0.139278909022978	0.999559101703025	0.999999999999999
GO:0005261	monoatomic cation channel activity	27/2525	341/18639	0.0791788856304985	0.584481286838361	0.999604419112334	0.999999999999999
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/2525	56/18639	0.0178571428571429	0.131817538896747	0.999715496674316	0.999999999999999
GO:0022836	gated channel activity	24/2525	318/18639	0.0754716981132075	0.557115636091911	0.999742501263738	0.999999999999999
GO:1901681	sulfur compound binding	19/2525	275/18639	0.0690909090909091	0.51001404140414	0.999847290744309	0.999999999999999
GO:0099094	ligand-gated monoatomic cation channel activity	6/2525	136/18639	0.0441176470588235	0.325666860803727	0.999893367092536	0.999999999999999
GO:0008201	heparin binding	9/2525	172/18639	0.0523255813953488	0.386256044209072	0.999895061166711	0.999999999999999
GO:0022824	transmitter-gated monoatomic ion channel activity	1/2525	63/18639	0.0158730158730159	0.117171145685997	0.999897661383113	0.999999999999999
GO:0022835	transmitter-gated channel activity	1/2525	63/18639	0.0158730158730159	0.117171145685997	0.999897661383113	0.999999999999999
GO:0030594	neurotransmitter receptor activity	3/2525	97/18639	0.0309278350515464	0.228302541594366	0.999906453838418	0.999999999999999
GO:0098960	postsynaptic neurotransmitter receptor activity	1/2525	69/18639	0.0144927536231884	0.106982350408954	0.999957412345895	0.999999999999999
GO:0005539	glycosaminoglycan binding	14/2525	242/18639	0.0578512396694215	0.427045249979543	0.999972833377997	0.999999999999999
GO:0015276	ligand-gated monoatomic ion channel activity	9/2525	186/18639	0.0483870967741935	0.357183008623443	0.9999752280679	0.999999999999999
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/2525	73/18639	0.0136986301369863	0.101120303811203	0.999976265892587	0.999999999999999
GO:0022834	ligand-gated channel activity	9/2525	188/18639	0.0478723404255319	0.353383189382768	0.999979919875478	0.999999999999999
GO:0003730	mRNA 3'-UTR binding	15/2525	262/18639	0.0572519083969466	0.422621117073539	0.999988347385834	0.999999999999999
GO:0030371	translation repressor activity	6/2525	329/18639	0.0182370820668693	0.134622167383912	0.999999999999996	0.999999999999999
GO:0045182	translation regulator activity	7/2525	356/18639	0.0196629213483146	0.145147402380687	0.999999999999999	0.999999999999999