ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 20/788 68/18639 0.294117647058824 6.95692744102717 3.16841534206926e-12 3.01949982099201e-09 GO:0009055 electron transfer activity 24/788 116/18639 0.206896551724138 4.89383861368808 8.27677391818602e-11 3.94388277201564e-08 GO:0015078 proton transmembrane transporter activity 30/788 185/18639 0.162162162162162 3.83571134586363 2.25889507456118e-10 7.175756686856e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 23/788 118/18639 0.194915254237288 4.6104383549858 7.14692666646107e-10 1.70275527828435e-07 GO:0015399 primary active transmembrane transporter activity 25/788 166/18639 0.150602409638554 3.56228212341753 3.30301068642217e-08 6.29553836832066e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 12/788 41/18639 0.292682926829268 6.92299120960753 7.64372021227251e-08 1.21407756038262e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 14/788 58/18639 0.241379310344828 5.70947838263609 9.32666985881541e-08 1.2697594822073e-05 GO:0003954 NADH dehydrogenase activity 12/788 44/18639 0.272727272727273 6.45096908167974 1.81582712357606e-07 2.16310406095998e-05 GO:0016651 oxidoreductase activity, acting on NAD(P)H 15/788 88/18639 0.170454545454545 4.03185567604984 3.844579408622e-06 0.000407098241824085 GO:0004129 cytochrome-c oxidase activity 6/788 15/18639 0.4 9.46142131979695 2.01987934594733e-05 0.0019249450166878 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/788 16/18639 0.375 8.87008248730965 3.11633708127595e-05 0.00269988112586908 GO:0016209 antioxidant activity 13/788 86/18639 0.151162790697674 3.57553712666745 6.26365955046624e-05 0.00497438962632861 GO:0003735 structural constituent of ribosome 19/788 175/18639 0.108571428571429 2.56810007251632 0.00015919386752138 0.0116701350575289 GO:0044548 S100 protein binding 5/788 14/18639 0.357142857142857 8.44769760696157 0.000194063662448494 0.0132101907366725 GO:0004602 glutathione peroxidase activity 6/788 23/18639 0.260869565217391 6.17049216508497 0.000304766259631819 0.0193628163619415 GO:0022804 active transmembrane transporter activity 35/788 457/18639 0.0765864332603939 1.81154128114274 0.000538090028187799 0.0304239712792543 GO:0016783 sulfurtransferase activity 4/788 10/18639 0.4 9.46142131979695 0.000542715122505061 0.0304239712792543 GO:0003712 transcription coregulator activity 37/788 495/18639 0.0747474747474747 1.76804337794186 0.000597004107345301 0.0316080507944485 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 5/788 18/18639 0.277777777777778 6.57043147208122 0.000721306306426586 0.0343702455012268 GO:0098641 cadherin binding involved in cell-cell adhesion 5/788 18/18639 0.277777777777778 6.57043147208122 0.000721306306426586 0.0343702455012268 GO:0004364 glutathione transferase activity 6/788 27/18639 0.222222222222222 5.25634517766497 0.000773522587483454 0.0351031917081777 GO:0035259 nuclear glucocorticoid receptor binding 4/788 12/18639 0.333333333333333 7.88451776649746 0.00119537177702843 0.0517813319776404 GO:0016860 intramolecular oxidoreductase activity 8/788 53/18639 0.150943396226415 3.57034766784791 0.00161603305790549 0.0669599784427795 GO:0048306 calcium-dependent protein binding 10/788 80/18639 0.125 2.95669416243655 0.00195262651865614 0.0775355446783042 GO:0098632 cell-cell adhesion mediator activity 8/788 55/18639 0.145454545454545 3.44051684356253 0.00206153490386334 0.0785857105352707 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 6/788 33/18639 0.181818181818182 4.30064605445316 0.00233287247495301 0.0855087487934699 GO:0004601 peroxidase activity 8/788 57/18639 0.140350877192982 3.31979695431472 0.00259834158201243 0.0915689535161156 GO:0051117 ATPase binding 10/788 84/18639 0.119047619047619 2.81589920232052 0.00281606295904626 0.0915689535161156 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/788 15/18639 0.266666666666667 6.30761421319797 0.00297863332528812 0.0915689535161156 GO:0031386 protein tag activity 4/788 15/18639 0.266666666666667 6.30761421319797 0.00297863332528812 0.0915689535161156 GO:0141047 molecular tag activity 4/788 15/18639 0.266666666666667 6.30761421319797 0.00297863332528812 0.0915689535161156 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/788 59/18639 0.135593220338983 3.20726146433795 0.00323859699319256 0.0964494667035159 GO:0015252 proton channel activity 5/788 27/18639 0.185185185185185 4.38028764805415 0.00496020391812163 0.143244676786967 GO:0071949 FAD binding 6/788 40/18639 0.15 3.54803299492386 0.00629607332254856 0.171581276468403 GO:0003713 transcription coactivator activity 20/788 256/18639 0.078125 1.84793385152284 0.00630151592486266 0.171581276468403 GO:0005126 cytokine receptor binding 21/788 275/18639 0.0763636363636364 1.80627134287033 0.00671681418382358 0.177808997699552 GO:0001618 virus receptor activity 9/788 81/18639 0.111111111111111 2.62817258883249 0.00708923301555346 0.181245275404898 GO:0031996 thioesterase binding 3/788 10/18639 0.3 7.09606598984772 0.00722698894584064 0.181245275404898 GO:0140272 exogenous protein binding 9/788 82/18639 0.109756097560976 2.59612170360282 0.00767318816586923 0.185594964857701 GO:0003779 actin binding 30/788 443/18639 0.0677200902934537 1.60182076520264 0.00778992507272618 0.185594964857701 GO:0045296 cadherin binding 24/788 334/18639 0.0718562874251497 1.69965652451442 0.00823303745332181 0.191367919341846 GO:0005164 tumor necrosis factor receptor binding 5/788 31/18639 0.161290322580645 3.81508924185361 0.00908588015484997 0.20146153368576 GO:0005085 guanyl-nucleotide exchange factor activity 18/788 230/18639 0.0782608695652174 1.85114764952549 0.00909007969411087 0.20146153368576 GO:0032050 clathrin heavy chain binding 3/788 11/18639 0.272727272727273 6.45096908167974 0.00962796689897014 0.208533010334512 GO:0043425 bHLH transcription factor binding 5/788 32/18639 0.15625 3.69586770304569 0.0104020809402539 0.220292958579155 GO:0140303 intramembrane lipid transporter activity 6/788 45/18639 0.133333333333333 3.15380710659898 0.0111865582530444 0.231756304677203 GO:0042301 phosphate ion binding 3/788 12/18639 0.25 5.9133883248731 0.0124388319396174 0.252217166775647 GO:0003714 transcription corepressor activity 16/788 204/18639 0.0784313725490196 1.85518065094058 0.0131536836361955 0.261155427193631 GO:0098631 cell adhesion mediator activity 8/788 76/18639 0.105263157894737 2.48984771573604 0.0147572115462858 0.287012706196129 GO:0019855 calcium channel inhibitor activity 3/788 13/18639 0.230769230769231 5.45851229988286 0.0156697196223508 0.292808682354907 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/788 13/18639 0.230769230769231 5.45851229988286 0.0156697196223508 0.292808682354907 GO:0050699 WW domain binding 4/788 24/18639 0.166666666666667 3.94225888324873 0.0171582496720087 0.314457921873544 GO:0032813 tumor necrosis factor receptor superfamily binding 6/788 50/18639 0.12 2.83842639593909 0.0182901370556296 0.328877370075755 GO:0005319 lipid transporter activity 14/788 178/18639 0.0786516853932584 1.86039183254434 0.0191123781761419 0.337298081515986 GO:0120020 cholesterol transfer activity 4/788 25/18639 0.16 3.78456852791878 0.0197598114453941 0.342383641953828 GO:0016846 carbon-sulfur lyase activity 3/788 15/18639 0.2 4.73071065989848 0.0234142376368282 0.398460151212451 GO:0005548 phospholipid transporter activity 7/788 68/18639 0.102941176470588 2.43492460435951 0.0244188852008191 0.401227544765182 GO:0032934 sterol binding 7/788 68/18639 0.102941176470588 2.43492460435951 0.0244188852008191 0.401227544765182 GO:0015036 disulfide oxidoreductase activity 5/788 40/18639 0.125 2.95669416243655 0.0258092237708713 0.40348030647063 GO:0015485 cholesterol binding 6/788 54/18639 0.111111111111111 2.62817258883249 0.0258261266471232 0.40348030647063 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/788 54/18639 0.111111111111111 2.62817258883249 0.0258261266471232 0.40348030647063 GO:0030414 peptidase inhibitor activity 13/788 169/18639 0.0769230769230769 1.81950409996095 0.0274168838785041 0.421424037680878 GO:0140328 floppase activity 3/788 16/18639 0.1875 4.43504124365482 0.0279313711780847 0.42251740845579 GO:0017080 sodium channel regulator activity 5/788 41/18639 0.121951219512195 2.8845796706698 0.0284052884367384 0.422972498128308 GO:0050660 flavin adenine dinucleotide binding 8/788 86/18639 0.0930232558139535 2.20033053948766 0.0288733001978462 0.423327001362267 GO:0061134 peptidase regulator activity 16/788 226/18639 0.0707964601769911 1.67458784421185 0.0309292574569744 0.446599732674191 GO:0038191 neuropilin binding 3/788 17/18639 0.176470588235294 4.1741564646163 0.0328762014944482 0.467627164540435 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/788 30/18639 0.133333333333333 3.15380710659898 0.0362945838167781 0.508657917314552 GO:0043021 ribonucleoprotein complex binding 13/788 177/18639 0.0734463276836158 1.73726662651639 0.037822294427034 0.520666146320477 GO:0017128 phospholipid scramblase activity 3/788 18/18639 0.166666666666667 3.94225888324873 0.0382441030875481 0.520666146320477 GO:0019003 GDP binding 7/788 75/18639 0.0933333333333333 2.20766497461929 0.0389533357758261 0.522852521047355 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 6/788 60/18639 0.1 2.36535532994924 0.0405856441111432 0.5311399438502 GO:0004866 endopeptidase inhibitor activity 12/788 161/18639 0.0745341614906832 1.76299776145285 0.0407862484940626 0.5311399438502 GO:0017022 myosin binding 7/788 76/18639 0.0921052631578947 2.17861675126904 0.0414080150454895 0.5311399438502 GO:0016853 isomerase activity 13/788 180/18639 0.0722222222222222 1.70831218274112 0.0423657183231839 0.5311399438502 GO:0030695 GTPase regulator activity 29/788 489/18639 0.0593047034764826 1.40276696459157 0.0424646469309573 0.5311399438502 GO:0060589 nucleoside-triphosphatase regulator activity 29/788 490/18639 0.0591836734693878 1.39990417486792 0.0433992414245686 0.5311399438502 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 6/788 61/18639 0.0983606557377049 2.32657901306482 0.0434721045333847 0.5311399438502 GO:0120015 sterol transfer activity 4/788 32/18639 0.125 2.95669416243655 0.0446002774403117 0.533967317199762 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 10/788 128/18639 0.078125 1.84793385152284 0.0449710333992027 0.533967317199762 GO:0042562 hormone binding 8/788 94/18639 0.0851063829787234 2.01306836591425 0.0453844204545443 0.533967317199762 GO:0004867 serine-type endopeptidase inhibitor activity 8/788 95/18639 0.0842105263157895 1.99187817258883 0.0478076693169177 0.555618400719787 GO:0061135 endopeptidase regulator activity 13/788 184/18639 0.0706521739130435 1.67117496137718 0.049001189039911 0.55726131658431 GO:0030296 protein tyrosine kinase activator activity 4/788 33/18639 0.121212121212121 2.86709736963544 0.0491185210840315 0.55726131658431 GO:0005201 extracellular matrix structural constituent 12/788 168/18639 0.0714285714285714 1.68953952139231 0.053302276422441 0.59389823075458 GO:0008376 acetylgalactosaminyltransferase activity 4/788 34/18639 0.117647058823529 2.78277097641087 0.0538791656094648 0.59389823075458 GO:0001222 transcription corepressor binding 5/788 49/18639 0.102040816326531 2.4136278877033 0.0550674837176469 0.59389823075458 GO:0060590 ATPase regulator activity 5/788 49/18639 0.102040816326531 2.4136278877033 0.0550674837176469 0.59389823075458 GO:0031625 ubiquitin protein ligase binding 19/788 302/18639 0.0629139072847682 1.48813745923959 0.0554637382341633 0.59389823075458 GO:0120013 lipid transfer activity 6/788 65/18639 0.0923076923076923 2.18340491995314 0.0562799719492659 0.59594236964056 GO:0051015 actin filament binding 14/788 209/18639 0.0669856459330144 1.58444854637748 0.0606373162057404 0.611183775000859 GO:0044325 transmembrane transporter binding 10/788 136/18639 0.0735294117647059 1.73923186025679 0.0628518110181037 0.611183775000859 GO:0004033 aldo-keto reductase (NADPH) activity 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.611183775000859 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.611183775000859 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.611183775000859 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.611183775000859 GO:0005345 purine nucleobase transmembrane transporter activity 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.611183775000859 GO:0005528 FK506 binding 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.611183775000859 GO:0019911 structural constituent of myelin sheath 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.611183775000859 GO:0070513 death domain binding 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.611183775000859 GO:0005080 protein kinase C binding 5/788 52/18639 0.0961538461538462 2.27438012495119 0.0678307090260867 0.633751624528045 GO:0030159 signaling receptor complex adaptor activity 5/788 52/18639 0.0961538461538462 2.27438012495119 0.0678307090260867 0.633751624528045 GO:0005125 cytokine activity 15/788 234/18639 0.0641025641025641 1.51625341663413 0.0723191390165754 0.660556815748998 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/788 122/18639 0.0737704918032787 1.74493425979862 0.0738372753289264 0.660556815748998 GO:0016782 transferase activity, transferring sulphur-containing groups 6/788 70/18639 0.0857142857142857 2.02744742567078 0.0751651555027493 0.660556815748998 GO:0003953 NAD+ nucleosidase activity 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.660556815748998 GO:0015173 aromatic amino acid transmembrane transporter activity 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.660556815748998 GO:0015205 nucleobase transmembrane transporter activity 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.660556815748998 GO:0019206 nucleoside kinase activity 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.660556815748998 GO:0032794 GTPase activating protein binding 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.660556815748998 GO:0050661 NADP binding 5/788 54/18639 0.0925925925925926 2.19014382402707 0.077174090599783 0.662584759834173 GO:0035035 histone acetyltransferase binding 3/788 24/18639 0.125 2.95669416243655 0.0788500616612679 0.662677018056068 GO:0070300 phosphatidic acid binding 3/788 24/18639 0.125 2.95669416243655 0.0788500616612679 0.662677018056068 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/788 39/18639 0.102564102564103 2.4260054666146 0.0812375223020128 0.662677018056068 GO:0140313 molecular sequestering activity 5/788 55/18639 0.0909090909090909 2.15032302722658 0.082092554168711 0.662677018056068 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 7/788 89/18639 0.0786516853932584 1.86039183254434 0.0825093013157808 0.662677018056068 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 7/788 89/18639 0.0786516853932584 1.86039183254434 0.0825093013157808 0.662677018056068 GO:0042379 chemokine receptor binding 6/788 72/18639 0.0833333333333333 1.97112944162437 0.0836126326096933 0.662677018056068 GO:0140793 histone H2AXY142 phosphatase activity 7/788 90/18639 0.0777777777777778 1.83972081218274 0.0863893684867139 0.662677018056068 GO:0005496 steroid binding 8/788 108/18639 0.0740740740740741 1.75211505922166 0.0870101197484114 0.662677018056068 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/788 40/18639 0.1 2.36535532994924 0.0873962221388063 0.662677018056068 GO:0000340 RNA 7-methylguanosine cap binding 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.662677018056068 GO:0004032 aldose reductase (NADPH) activity 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.662677018056068 GO:0004300 enoyl-CoA hydratase activity 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.662677018056068 GO:0005436 sodium:phosphate symporter activity 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.662677018056068 GO:0005527 macrolide binding 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.662677018056068 GO:0070008 serine-type exopeptidase activity 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.662677018056068 GO:0070410 co-SMAD binding 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.662677018056068 GO:0044389 ubiquitin-like protein ligase binding 19/788 322/18639 0.0590062111801242 1.39570656115017 0.0905666339627472 0.669069784236419 GO:0043178 alcohol binding 7/788 92/18639 0.0760869565217391 1.79972688148312 0.0944553030029177 0.677497862082292 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/788 26/18639 0.115384615384615 2.72925614994143 0.0952968936859087 0.677497862082292 GO:0035591 signaling adaptor activity 9/788 129/18639 0.0697674418604651 1.65024790461575 0.0964363886321893 0.677497862082292 GO:0019209 kinase activator activity 10/788 148/18639 0.0675675675675676 1.59821306077651 0.0972857568754933 0.677497862082292 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/788 130/18639 0.0692307692307692 1.63755368996486 0.099959316439524 0.677497862082292 GO:0016247 channel regulator activity 11/788 168/18639 0.0654761904761905 1.54874456127629 0.100335607527284 0.677497862082292 GO:0016859 cis-trans isomerase activity 4/788 42/18639 0.0952380952380952 2.25271936185642 0.100364433566636 0.677497862082292 GO:0048487 beta-tubulin binding 4/788 42/18639 0.0952380952380952 2.25271936185642 0.100364433566636 0.677497862082292 GO:0005172 vascular endothelial growth factor receptor binding 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.677497862082292 GO:0008035 high-density lipoprotein particle binding 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.677497862082292 GO:0035673 oligopeptide transmembrane transporter activity 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.677497862082292 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.677497862082292 GO:0089720 caspase binding 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.677497862082292 GO:0140333 glycerophospholipid flippase activity 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.677497862082292 GO:0033218 amide binding 15/788 247/18639 0.0607287449392713 1.43645060523233 0.102371135508762 0.677497862082292 GO:0004879 nuclear receptor activity 5/788 59/18639 0.0847457627118644 2.00453841521122 0.103368001500785 0.678860816304251 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/788 27/18639 0.111111111111111 2.62817258883249 0.104001761994145 0.678860816304251 GO:0141108 transporter regulator activity 11/788 170/18639 0.0647058823529412 1.53052403702598 0.106666087624343 0.6858011349576 GO:0008200 ion channel inhibitor activity 4/788 43/18639 0.0930232558139535 2.20033053948766 0.10716300808813 0.6858011349576 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 9/788 132/18639 0.0681818181818182 1.61274227041994 0.107223892034294 0.6858011349576 GO:0098531 ligand-modulated transcription factor activity 5/788 60/18639 0.0833333333333333 1.97112944162437 0.109075488536208 0.691968782383369 GO:0045499 chemorepellent activity 3/788 28/18639 0.107142857142857 2.53430928208847 0.113006502071376 0.691968782383369 GO:0097718 disordered domain specific binding 3/788 28/18639 0.107142857142857 2.53430928208847 0.113006502071376 0.691968782383369 GO:0016248 channel inhibitor activity 4/788 44/18639 0.0909090909090909 2.15032302722658 0.114163353596847 0.691968782383369 GO:0019905 syntaxin binding 5/788 61/18639 0.0819672131147541 1.93881584422069 0.11493293353646 0.691968782383369 GO:0004857 enzyme inhibitor activity 23/788 416/18639 0.0552884615384615 1.30776857184693 0.115500295289349 0.691968782383369 GO:0004705 JUN kinase activity 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.691968782383369 GO:0005545 1-phosphatidylinositol binding 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.691968782383369 GO:0008195 phosphatidate phosphatase activity 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.691968782383369 GO:0016530 metallochaperone activity 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.691968782383369 GO:1901474 azole transmembrane transporter activity 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.691968782383369 GO:0015370 solute:sodium symporter activity 6/788 79/18639 0.0759493670886076 1.79647240249309 0.117083445583552 0.693046730690215 GO:0015294 solute:monoatomic cation symporter activity 8/788 116/18639 0.0689655172413793 1.63127953789603 0.118308832576439 0.695506453801921 GO:0004725 protein tyrosine phosphatase activity 7/788 98/18639 0.0714285714285714 1.68953952139231 0.121048950191253 0.695506453801921 GO:0046915 transition metal ion transmembrane transporter activity 4/788 45/18639 0.0888888888888889 2.10253807106599 0.121359175670252 0.695506453801921 GO:0141110 transporter inhibitor activity 4/788 45/18639 0.0888888888888889 2.10253807106599 0.121359175670252 0.695506453801921 GO:0140789 histone phosphatase activity 9/788 136/18639 0.0661764705882353 1.56530867423111 0.122616854130144 0.695506453801921 GO:0016922 nuclear receptor binding 9/788 137/18639 0.0656934306569343 1.5538830634703 0.126642164475536 0.695506453801921 GO:0033192 calmodulin-dependent protein phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:0140791 histone H2AXS140 phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:1990439 MAP kinase serine/threonine phosphatase activity 6/788 81/18639 0.0740740740740741 1.75211505922166 0.127716295294162 0.695506453801921 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.706336337755372 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 6/788 82/18639 0.0731707317073171 1.73074780240188 0.133202035310271 0.712741507236266 GO:0033549 MAP kinase phosphatase activity 6/788 82/18639 0.0731707317073171 1.73074780240188 0.133202035310271 0.712741507236266 GO:0030295 protein kinase activator activity 9/788 139/18639 0.0647482014388489 1.53152503378008 0.134901033077353 0.712741507236266 GO:0001784 phosphotyrosine residue binding 4/788 47/18639 0.0851063829787234 2.01306836591425 0.136310740979659 0.712741507236266 GO:0001540 amyloid-beta binding 6/788 83/18639 0.072289156626506 1.70989541924041 0.138797809621978 0.712741507236266 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 6/788 83/18639 0.072289156626506 1.70989541924041 0.138797809621978 0.712741507236266 GO:0099106 ion channel regulator activity 10/788 160/18639 0.0625 1.47834708121827 0.140913973532106 0.712741507236266 GO:0017018 myosin phosphatase activity 6/788 84/18639 0.0714285714285714 1.68953952139231 0.144501349625039 0.712741507236266 GO:0004707 MAP kinase activity 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0005521 lamin binding 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0008142 oxysterol binding 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0016722 oxidoreductase activity, acting on metal ions 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0017070 U6 snRNA binding 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0030275 LRR domain binding 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0070411 I-SMAD binding 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0140327 flippase activity 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.712741507236266 GO:0022884 macromolecule transmembrane transporter activity 3/788 32/18639 0.09375 2.21752062182741 0.151697041107438 0.741370667566093 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/788 67/18639 0.0746268656716418 1.76519054473824 0.153040462291195 0.744120206956678 GO:0004549 tRNA-specific ribonuclease activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0005092 GDP-dissociation inhibitor activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0008429 phosphatidylethanolamine binding 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0009881 photoreceptor activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0015278 intracellularly gated calcium channel activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0032977 membrane insertase activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.745618420935355 GO:0000149 SNARE binding 7/788 106/18639 0.0660377358490566 1.56202710468346 0.16176981206803 0.745618420935355 GO:0140311 protein sequestering activity 3/788 33/18639 0.0909090909090909 2.15032302722658 0.161954893109778 0.745618420935355 GO:0140416 transcription regulator inhibitor activity 3/788 33/18639 0.0909090909090909 2.15032302722658 0.161954893109778 0.745618420935355 GO:0015293 symporter activity 9/788 146/18639 0.0616438356164384 1.45809575133857 0.165913259078139 0.760169884141664 GO:0015020 glucuronosyltransferase activity 3/788 34/18639 0.0882352941176471 2.08707823230815 0.172413834480776 0.776935488516069 GO:0015035 protein-disulfide reductase activity 3/788 34/18639 0.0882352941176471 2.08707823230815 0.172413834480776 0.776935488516069 GO:0015280 ligand-gated sodium channel activity 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.776935488516069 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.776935488516069 GO:0030228 lipoprotein particle receptor activity 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.776935488516069 GO:0050811 GABA receptor binding 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.776935488516069 GO:0070628 proteasome binding 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.776935488516069 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/788 52/18639 0.0769230769230769 1.81950409996095 0.176624888183671 0.779275548328882 GO:0004864 protein phosphatase inhibitor activity 4/788 53/18639 0.0754716981132075 1.78517383392395 0.185131438280864 0.80329644957362 GO:0005246 calcium channel regulator activity 4/788 53/18639 0.0754716981132075 1.78517383392395 0.185131438280864 0.80329644957362 GO:0140297 DNA-binding transcription factor binding 25/788 488/18639 0.0512295081967213 1.21175990263793 0.186674888035021 0.80329644957362 GO:0003756 protein disulfide isomerase activity 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.80329644957362 GO:0008381 mechanosensitive monoatomic ion channel activity 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.80329644957362 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.80329644957362 GO:0016918 retinal binding 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.80329644957362 GO:0042577 lipid phosphatase activity 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.80329644957362 GO:0097001 ceramide binding 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.80329644957362 GO:0008017 microtubule binding 15/788 276/18639 0.0543478260869565 1.28551920105937 0.19298350245888 0.80329644957362 GO:0051287 NAD binding 4/788 54/18639 0.0740740740740741 1.75211505922166 0.193768026095351 0.80329644957362 GO:0005484 SNAP receptor activity 3/788 36/18639 0.0833333333333333 1.97112944162437 0.193870077021965 0.80329644957362 GO:0016409 palmitoyltransferase activity 3/788 36/18639 0.0833333333333333 1.97112944162437 0.193870077021965 0.80329644957362 GO:0045505 dynein intermediate chain binding 3/788 36/18639 0.0833333333333333 1.97112944162437 0.193870077021965 0.80329644957362 GO:0043022 ribosome binding 7/788 112/18639 0.0625 1.47834708121827 0.195825639061625 0.807886727384108 GO:0051219 phosphoprotein binding 6/788 93/18639 0.0645161290322581 1.52603569674144 0.200261959589807 0.822627790901235 GO:0000339 RNA cap binding 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.830018258197438 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.830018258197438 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.830018258197438 GO:0016505 peptidase activator activity involved in apoptotic process 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.830018258197438 GO:0016410 N-acyltransferase activity 6/788 94/18639 0.0638297872340425 1.50980127443568 0.206898574178789 0.830018258197438 GO:0004721 phosphoprotein phosphatase activity 10/788 175/18639 0.0571428571428571 1.35163161711385 0.207286826286454 0.830018258197438 GO:0019212 phosphatase inhibitor activity 4/788 56/18639 0.0714285714285714 1.68953952139231 0.211400239721352 0.840021004290288 GO:0005543 phospholipid binding 25/788 497/18639 0.0503018108651912 1.18981656436078 0.21154778701959 0.840021004290288 GO:0001221 transcription coregulator binding 7/788 115/18639 0.0608695652173913 1.43978150518649 0.213836307061131 0.845585064851691 GO:0042887 amide transmembrane transporter activity 3/788 38/18639 0.0789473684210526 1.86738578680203 0.215938335978868 0.846533315962426 GO:0017171 serine hydrolase activity 11/788 198/18639 0.0555555555555556 1.31408629441624 0.217728745246056 0.846533315962426 GO:0002020 protease binding 8/788 136/18639 0.0588235294117647 1.39138548820543 0.218104440438841 0.846533315962426 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.846533315962426 GO:0005123 death receptor binding 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.846533315962426 GO:0010314 phosphatidylinositol-5-phosphate binding 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.846533315962426 GO:0015174 basic amino acid transmembrane transporter activity 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.846533315962426 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.846533315962426 GO:0072542 protein phosphatase activator activity 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.846533315962426 GO:0005539 glycosaminoglycan binding 13/788 242/18639 0.0537190082644628 1.27064542517934 0.225811986077264 0.855678750226738 GO:0016829 lyase activity 11/788 200/18639 0.055 1.30094543147208 0.227077848993226 0.855678750226738 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/788 39/18639 0.0769230769230769 1.81950409996095 0.227163403785273 0.855678750226738 GO:0008970 phospholipase A1 activity 2/788 22/18639 0.0909090909090909 2.15032302722658 0.237898944520898 0.87287464059646 GO:0034062 5'-3' RNA polymerase activity 2/788 22/18639 0.0909090909090909 2.15032302722658 0.237898944520898 0.87287464059646 GO:0097747 RNA polymerase activity 2/788 22/18639 0.0909090909090909 2.15032302722658 0.237898944520898 0.87287464059646 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/788 40/18639 0.075 1.77401649746193 0.238495877972824 0.87287464059646 GO:0071855 neuropeptide receptor binding 3/788 40/18639 0.075 1.77401649746193 0.238495877972824 0.87287464059646 GO:0031593 polyubiquitin modification-dependent protein binding 4/788 59/18639 0.0677966101694915 1.60363073216898 0.238629620273925 0.87287464059646 GO:0045309 protein phosphorylated amino acid binding 4/788 59/18639 0.0677966101694915 1.60363073216898 0.238629620273925 0.87287464059646 GO:0046332 SMAD binding 5/788 79/18639 0.0632911392405063 1.49706033541091 0.241748436334145 0.87287464059646 GO:0140318 protein transporter activity 3/788 41/18639 0.0731707317073171 1.73074780240188 0.249921319361978 0.87287464059646 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.87287464059646 GO:0005283 amino acid:sodium symporter activity 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.87287464059646 GO:0017134 fibroblast growth factor binding 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.87287464059646 GO:0042171 lysophosphatidic acid acyltransferase activity 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.87287464059646 GO:0071617 lysophospholipid acyltransferase activity 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.87287464059646 GO:0140103 catalytic activity, acting on a glycoprotein 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.87287464059646 GO:0016836 hydro-lyase activity 4/788 61/18639 0.0655737704918033 1.55105267537655 0.257213350215402 0.87287464059646 GO:0051020 GTPase binding 16/788 315/18639 0.0507936507936508 1.20145032632342 0.260320147985717 0.87287464059646 GO:0042056 chemoattractant activity 3/788 42/18639 0.0714285714285714 1.68953952139231 0.261425695192389 0.87287464059646 GO:0015179 L-amino acid transmembrane transporter activity 4/788 62/18639 0.0645161290322581 1.52603569674144 0.266611703233562 0.87287464059646 GO:0000287 magnesium ion binding 12/788 230/18639 0.0521739130434783 1.23409843301699 0.268267672863018 0.87287464059646 GO:0005315 phosphate transmembrane transporter activity 2/788 24/18639 0.0833333333333333 1.97112944162437 0.269683685493414 0.87287464059646 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/788 24/18639 0.0833333333333333 1.97112944162437 0.269683685493414 0.87287464059646 GO:0030215 semaphorin receptor binding 2/788 24/18639 0.0833333333333333 1.97112944162437 0.269683685493414 0.87287464059646 GO:0004722 protein serine/threonine phosphatase activity 6/788 103/18639 0.058252427184466 1.37787689123257 0.269723271980457 0.87287464059646 GO:0008194 UDP-glycosyltransferase activity 8/788 145/18639 0.0551724137931034 1.30502363031682 0.270925471032993 0.87287464059646 GO:0016874 ligase activity 9/788 167/18639 0.0538922155688623 1.27474239338582 0.275486542764227 0.87287464059646 GO:0003707 nuclear steroid receptor activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.87287464059646 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.87287464059646 GO:0019211 phosphatase activator activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.87287464059646 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.87287464059646 GO:0019707 protein-cysteine S-acyltransferase activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.87287464059646 GO:0001217 DNA-binding transcription repressor activity 14/788 278/18639 0.0503597122302158 1.19118613738451 0.288834409829125 0.87287464059646 GO:0008009 chemokine activity 3/788 45/18639 0.0666666666666667 1.57690355329949 0.296278544815852 0.87287464059646 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/788 86/18639 0.0581395348837209 1.37520658717979 0.298680424441287 0.87287464059646 GO:0019888 protein phosphatase regulator activity 6/788 107/18639 0.0560747663551402 1.32636747473789 0.299040311628092 0.87287464059646 GO:0005160 transforming growth factor beta receptor binding 2/788 26/18639 0.0769230769230769 1.81950409996095 0.301433934170908 0.87287464059646 GO:0008157 protein phosphatase 1 binding 2/788 26/18639 0.0769230769230769 1.81950409996095 0.301433934170908 0.87287464059646 GO:0008198 ferrous iron binding 2/788 26/18639 0.0769230769230769 1.81950409996095 0.301433934170908 0.87287464059646 GO:0030507 spectrin binding 2/788 26/18639 0.0769230769230769 1.81950409996095 0.301433934170908 0.87287464059646 GO:0070412 R-SMAD binding 2/788 26/18639 0.0769230769230769 1.81950409996095 0.301433934170908 0.87287464059646 GO:0008201 heparin binding 9/788 172/18639 0.0523255813953488 1.23768592846181 0.30429129048521 0.87287464059646 GO:0008236 serine-type peptidase activity 10/788 194/18639 0.0515463917525773 1.2192553247161 0.305897127568149 0.87287464059646 GO:0004180 carboxypeptidase activity 3/788 46/18639 0.0652173913043478 1.54262304127124 0.307967007880134 0.87287464059646 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/788 46/18639 0.0652173913043478 1.54262304127124 0.307967007880134 0.87287464059646 GO:0030276 clathrin binding 3/788 46/18639 0.0652173913043478 1.54262304127124 0.307967007880134 0.87287464059646 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 17/788 349/18639 0.0487106017191977 1.15217881401539 0.308771586331533 0.87287464059646 GO:0031267 small GTPase binding 14/788 283/18639 0.049469964664311 1.17014044591128 0.311424542218046 0.87287464059646 GO:0016500 protein-hormone receptor activity 4/788 67/18639 0.0597014925373134 1.41215243579059 0.314375397871353 0.87287464059646 GO:0001671 ATPase activator activity 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.87287464059646 GO:0005385 zinc ion transmembrane transporter activity 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.87287464059646 GO:0008320 protein transmembrane transporter activity 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.87287464059646 GO:0008395 steroid hydroxylase activity 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.87287464059646 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.87287464059646 GO:0035255 ionotropic glutamate receptor binding 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.87287464059646 GO:0043495 protein-membrane adaptor activity 3/788 47/18639 0.0638297872340425 1.50980127443568 0.319670844259712 0.87287464059646 GO:0003777 microtubule motor activity 4/788 68/18639 0.0588235294117647 1.39138548820543 0.324033168420095 0.87287464059646 GO:0004252 serine-type endopeptidase activity 9/788 176/18639 0.0511363636363636 1.20955670281495 0.327819838081682 0.87287464059646 GO:1902936 phosphatidylinositol bisphosphate binding 6/788 111/18639 0.0540540540540541 1.27857044862121 0.328919795784086 0.87287464059646 GO:0019207 kinase regulator activity 14/788 287/18639 0.0487804878048781 1.15383186826792 0.329824990955589 0.87287464059646 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/788 48/18639 0.0625 1.47834708121827 0.331378723487723 0.87287464059646 GO:0019789 SUMO transferase activity 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.87287464059646 GO:0046625 sphingolipid binding 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.87287464059646 GO:0051537 2 iron, 2 sulfur cluster binding 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.87287464059646 GO:0051959 dynein light intermediate chain binding 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.87287464059646 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.87287464059646 GO:0035254 glutamate receptor binding 3/788 49/18639 0.0612244897959184 1.44817673262198 0.343079784872768 0.87287464059646 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/788 70/18639 0.0571428571428571 1.35163161711385 0.343399872366567 0.87287464059646 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 13/788 268/18639 0.0485074626865672 1.14737385407985 0.34566967427746 0.87287464059646 GO:0005416 amino acid:monoatomic cation symporter activity 2/788 29/18639 0.0689655172413793 1.63127953789603 0.348541078876136 0.87287464059646 GO:0016417 S-acyltransferase activity 2/788 29/18639 0.0689655172413793 1.63127953789603 0.348541078876136 0.87287464059646 GO:0035250 UDP-galactosyltransferase activity 2/788 29/18639 0.0689655172413793 1.63127953789603 0.348541078876136 0.87287464059646 GO:0051861 glycolipid binding 2/788 29/18639 0.0689655172413793 1.63127953789603 0.348541078876136 0.87287464059646 GO:0099604 ligand-gated calcium channel activity 2/788 29/18639 0.0689655172413793 1.63127953789603 0.348541078876136 0.87287464059646 GO:0001094 TFIID-class transcription factor complex binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0004090 carbonyl reductase (NADPH) activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0004382 GDP phosphatase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0004935 adrenergic receptor activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0004955 prostaglandin receptor activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0005031 tumor necrosis factor receptor activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0005337 nucleoside transmembrane transporter activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0005381 iron ion transmembrane transporter activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0008401 retinoic acid 4-hydroxylase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0015187 glycine transmembrane transporter activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0030957 Tat protein binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0032052 bile acid binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0033204 ribonuclease P RNA binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0043121 neurotrophin binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0043295 glutathione binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0043422 protein kinase B binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0047429 nucleoside triphosphate diphosphatase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0097177 mitochondrial ribosome binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0140135 mechanosensitive monoatomic cation channel activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0141109 transporter activator activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:1990757 ubiquitin ligase activator activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.87287464059646 GO:0019838 growth factor binding 7/788 136/18639 0.0514705882352941 1.21746230217976 0.352484056486566 0.87287464059646 GO:0140299 molecular sensor activity 4/788 71/18639 0.0563380281690141 1.33259455208408 0.35309603707675 0.87287464059646 GO:0005096 GTPase activator activity 13/788 271/18639 0.0479704797047971 1.13467229849963 0.360343710962354 0.87287464059646 GO:0005518 collagen binding 4/788 72/18639 0.0555555555555556 1.31408629441624 0.362792508961982 0.87287464059646 GO:0042277 peptide binding 12/788 249/18639 0.0481927710843374 1.13993027949361 0.362797637231536 0.87287464059646 GO:0001968 fibronectin binding 2/788 30/18639 0.0666666666666667 1.57690355329949 0.364018979314258 0.87287464059646 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/788 30/18639 0.0666666666666667 1.57690355329949 0.364018979314258 0.87287464059646 GO:0031210 phosphatidylcholine binding 2/788 30/18639 0.0666666666666667 1.57690355329949 0.364018979314258 0.87287464059646 GO:0031624 ubiquitin conjugating enzyme binding 2/788 30/18639 0.0666666666666667 1.57690355329949 0.364018979314258 0.87287464059646 GO:0015631 tubulin binding 18/788 385/18639 0.0467532467532468 1.10588041400224 0.364398854844996 0.87287464059646 GO:0016791 phosphatase activity 13/788 273/18639 0.0476190476190476 1.12635968092821 0.370181330883186 0.87287464059646 GO:0004521 RNA endonuclease activity 4/788 73/18639 0.0547945205479452 1.29608511230095 0.372483327007186 0.87287464059646 GO:0019208 phosphatase regulator activity 6/788 117/18639 0.0512820512820513 1.2130027333073 0.374348090801158 0.87287464059646 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 11/788 229/18639 0.0480349344978166 1.13619688338173 0.375999667161203 0.87287464059646 GO:0001664 G protein-coupled receptor binding 14/788 297/18639 0.0471380471380471 1.11498231041378 0.376781917570667 0.87287464059646 GO:0008083 growth factor activity 8/788 162/18639 0.0493827160493827 1.16807670614777 0.37813508557185 0.87287464059646 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0000099 sulfur amino acid transmembrane transporter activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0004954 prostanoid receptor activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0005114 type II transforming growth factor beta receptor binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0008199 ferric iron binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0008432 JUN kinase binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0008503 benzodiazepine receptor activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0010854 adenylate cyclase regulator activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0019107 myristoyltransferase activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0031731 CCR6 chemokine receptor binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0034056 estrogen response element binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0034511 U3 snoRNA binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0043522 leucine zipper domain binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0045294 alpha-catenin binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0047676 arachidonate-CoA ligase activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0050786 RAGE receptor binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0070990 snRNP binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0097493 structural molecule activity conferring elasticity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0180030 inositol phosphate kinase activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:1900750 oligopeptide binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.87287464059646 GO:0005516 calmodulin binding 10/788 207/18639 0.0483091787439614 1.14268373427499 0.378912227973687 0.87287464059646 GO:0005184 neuropeptide hormone activity 2/788 31/18639 0.0645161290322581 1.52603569674144 0.379354307576368 0.87287464059646 GO:0008327 methyl-CpG binding 2/788 31/18639 0.0645161290322581 1.52603569674144 0.379354307576368 0.87287464059646 GO:0016411 acylglycerol O-acyltransferase activity 2/788 31/18639 0.0645161290322581 1.52603569674144 0.379354307576368 0.87287464059646 GO:0047499 calcium-independent phospholipase A2 activity 2/788 31/18639 0.0645161290322581 1.52603569674144 0.379354307576368 0.87287464059646 GO:0003684 damaged DNA binding 4/788 74/18639 0.0540540540540541 1.27857044862121 0.382162706543533 0.87287464059646 GO:0004896 cytokine receptor activity 5/788 96/18639 0.0520833333333333 1.23195590101523 0.382835240306817 0.87287464059646 GO:0034212 protein N-acetyltransferase activity 3/788 53/18639 0.0566037735849057 1.33888037544297 0.389615032064362 0.87287464059646 GO:0140296 general transcription initiation factor binding 3/788 53/18639 0.0566037735849057 1.33888037544297 0.389615032064362 0.87287464059646 GO:0015081 sodium ion transmembrane transporter activity 8/788 164/18639 0.0487804878048781 1.15383186826792 0.391052285974244 0.87287464059646 GO:0020037 heme binding 7/788 142/18639 0.0492957746478873 1.16602023307357 0.394192986641692 0.87287464059646 GO:0008378 galactosyltransferase activity 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.87287464059646 GO:0030515 snoRNA binding 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.87287464059646 GO:0047498 calcium-dependent phospholipase A2 activity 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.87287464059646 GO:0071813 lipoprotein particle binding 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.87287464059646 GO:0071814 protein-lipid complex binding 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.87287464059646 GO:0160041 neuropeptide activity 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.87287464059646 GO:0042626 ATPase-coupled transmembrane transporter activity 5/788 98/18639 0.0510204081632653 1.20681394385165 0.399736906118736 0.87287464059646 GO:0017069 snRNA binding 3/788 54/18639 0.0555555555555556 1.31408629441624 0.401135444180186 0.87287464059646 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/788 54/18639 0.0555555555555556 1.31408629441624 0.401135444180186 0.87287464059646 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0003995 acyl-CoA dehydrogenase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0004000 adenosine deaminase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0004126 cytidine deaminase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0004526 ribonuclease P activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0004859 phospholipase inhibitor activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0005078 MAP-kinase scaffold activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0005095 GTPase inhibitor activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0008179 adenylate cyclase binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0008504 monoamine transmembrane transporter activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0010853 cyclase activator activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0015166 polyol transmembrane transporter activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0016801 hydrolase activity, acting on ether bonds 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0016803 ether hydrolase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0016840 carbon-nitrogen lyase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0034452 dynactin binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0035197 siRNA binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0043047 single-stranded telomeric DNA binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0045295 gamma-catenin binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.87287464059646 GO:0003697 single-stranded DNA binding 6/788 121/18639 0.0495867768595041 1.17290346939632 0.404756254145305 0.87287464059646 GO:0019239 deaminase activity 2/788 33/18639 0.0606060606060606 1.43354868481772 0.409536398388137 0.87287464059646 GO:0043130 ubiquitin binding 5/788 100/18639 0.05 1.18267766497462 0.416588844206143 0.87287464059646 GO:0170055 lipid transmembrane transporter activity 3/788 56/18639 0.0535714285714286 1.26715464104423 0.423981935313191 0.87287464059646 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/788 34/18639 0.0588235294117647 1.39138548820543 0.424356558632348 0.87287464059646 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/788 34/18639 0.0588235294117647 1.39138548820543 0.424356558632348 0.87287464059646 GO:0016831 carboxy-lyase activity 2/788 34/18639 0.0588235294117647 1.39138548820543 0.424356558632348 0.87287464059646 GO:0019825 oxygen binding 2/788 34/18639 0.0588235294117647 1.39138548820543 0.424356558632348 0.87287464059646 GO:0005035 death receptor activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0019104 DNA N-glycosylase activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0031432 titin binding 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0031994 insulin-like growth factor I binding 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0046974 histone H3K9 methyltransferase activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0061459 L-arginine transmembrane transporter activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0071837 HMG box domain binding 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:1901338 catecholamine binding 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.87287464059646 GO:0016835 carbon-oxygen lyase activity 4/788 79/18639 0.0506329113924051 1.19764826832873 0.43019822719922 0.87287464059646 GO:0033293 monocarboxylic acid binding 4/788 79/18639 0.0506329113924051 1.19764826832873 0.43019822719922 0.87287464059646 GO:0008238 exopeptidase activity 5/788 102/18639 0.0490196078431373 1.15948790683786 0.433362476247318 0.87287464059646 GO:0016504 peptidase activator activity 3/788 57/18639 0.0526315789473684 1.24492385786802 0.435293136764169 0.87287464059646 GO:0004623 phospholipase A2 activity 2/788 35/18639 0.0571428571428571 1.35163161711385 0.438980738843456 0.87287464059646 GO:0005154 epidermal growth factor receptor binding 2/788 35/18639 0.0571428571428571 1.35163161711385 0.438980738843456 0.87287464059646 GO:0005343 organic acid:sodium symporter activity 2/788 35/18639 0.0571428571428571 1.35163161711385 0.438980738843456 0.87287464059646 GO:0010485 histone H4 acetyltransferase activity 2/788 35/18639 0.0571428571428571 1.35163161711385 0.438980738843456 0.87287464059646 GO:0016229 steroid dehydrogenase activity 2/788 35/18639 0.0571428571428571 1.35163161711385 0.438980738843456 0.87287464059646 GO:0005253 monoatomic anion channel activity 5/788 103/18639 0.0485436893203883 1.14823074269381 0.441711415240525 0.87287464059646 GO:0015101 organic cation transmembrane transporter activity 4/788 81/18639 0.0493827160493827 1.16807670614777 0.449150294900465 0.87287464059646 GO:0030971 receptor tyrosine kinase binding 4/788 81/18639 0.0493827160493827 1.16807670614777 0.449150294900465 0.87287464059646 GO:0004519 endonuclease activity 6/788 127/18639 0.047244094488189 1.11749070706263 0.450102214468371 0.87287464059646 GO:0000993 RNA polymerase II complex binding 2/788 36/18639 0.0555555555555556 1.31408629441624 0.45339901306825 0.87287464059646 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/788 36/18639 0.0555555555555556 1.31408629441624 0.45339901306825 0.87287464059646 GO:0005161 platelet-derived growth factor receptor binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0005313 L-glutamate transmembrane transporter activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0008191 metalloendopeptidase inhibitor activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0008474 palmitoyl-(protein) hydrolase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0008494 translation activator activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0019992 diacylglycerol binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0030983 mismatched DNA binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0032036 myosin heavy chain binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0034236 protein kinase A catalytic subunit binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0042043 neurexin family protein binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0070742 C2H2 zinc finger domain binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0098599 palmitoyl hydrolase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0098847 sequence-specific single stranded DNA binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:1901612 cardiolipin binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.87287464059646 GO:0016758 hexosyltransferase activity 9/788 197/18639 0.0456852791878173 1.08061918627123 0.454402925483143 0.87287464059646 GO:0016757 glycosyltransferase activity 12/788 267/18639 0.0449438202247191 1.0630810471682 0.456008875758247 0.87287464059646 GO:0070888 E-box binding 3/788 59/18639 0.0508474576271186 1.20272304912673 0.45765744262941 0.87287464059646 GO:0046906 tetrapyrrole binding 7/788 152/18639 0.0460526315789474 1.08930837563452 0.463509341691017 0.87287464059646 GO:0004497 monooxygenase activity 5/788 106/18639 0.0471698113207547 1.11573364620247 0.466568221967572 0.87287464059646 GO:0019213 deacetylase activity 2/788 37/18639 0.0540540540540541 1.27857044862121 0.467602642447649 0.87287464059646 GO:0030280 structural constituent of skin epidermis 2/788 37/18639 0.0540540540540541 1.27857044862121 0.467602642447649 0.87287464059646 GO:0042805 actinin binding 2/788 37/18639 0.0540540540540541 1.27857044862121 0.467602642447649 0.87287464059646 GO:0043394 proteoglycan binding 2/788 37/18639 0.0540540540540541 1.27857044862121 0.467602642447649 0.87287464059646 GO:0030165 PDZ domain binding 4/788 83/18639 0.0481927710843374 1.13993027949361 0.467898020964559 0.87287464059646 GO:0001098 basal transcription machinery binding 3/788 60/18639 0.05 1.18267766497462 0.468698177145346 0.87287464059646 GO:0001099 basal RNA polymerase II transcription machinery binding 3/788 60/18639 0.05 1.18267766497462 0.468698177145346 0.87287464059646 GO:0000774 adenyl-nucleotide exchange factor activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0004089 carbonate dehydratase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0004467 long-chain fatty acid-CoA ligase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0004953 icosanoid receptor activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0005523 tropomyosin binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0008020 G protein-coupled photoreceptor activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0015250 water channel activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0015929 hexosaminidase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0017081 chloride channel regulator activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0031005 filamin binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0034483 heparan sulfate sulfotransferase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0048531 beta-1,3-galactosyltransferase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0050700 CARD domain binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0051371 muscle alpha-actinin binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0120283 protein serine/threonine kinase binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0140776 protein-containing complex destabilizing activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0141050 histone H3K deacetylase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0141051 histone H4K deacetylase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.87287464059646 GO:0005506 iron ion binding 7/788 154/18639 0.0454545454545455 1.07516151361329 0.477195894806669 0.87287464059646 GO:0000146 microfilament motor activity 2/788 38/18639 0.0526315789473684 1.24492385786802 0.481583992807025 0.874189609800181 GO:0005501 retinoid binding 2/788 38/18639 0.0526315789473684 1.24492385786802 0.481583992807025 0.874189609800181 GO:0019840 isoprenoid binding 2/788 38/18639 0.0526315789473684 1.24492385786802 0.481583992807025 0.874189609800181 GO:0042162 telomeric DNA binding 2/788 38/18639 0.0526315789473684 1.24492385786802 0.481583992807025 0.874189609800181 GO:0005179 hormone activity 6/788 132/18639 0.0454545454545455 1.07516151361329 0.487298300672152 0.879262986631788 GO:0046982 protein heterodimerization activity 16/788 369/18639 0.043360433604336 1.02562832734926 0.495039399669724 0.879262986631788 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/788 39/18639 0.0512820512820513 1.2130027333073 0.495336457078472 0.879262986631788 GO:1901681 sulfur compound binding 12/788 275/18639 0.0436363636363636 1.03215505306876 0.497159989526466 0.879262986631788 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0005159 insulin-like growth factor receptor binding 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0015378 sodium:chloride symporter activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0019841 retinol binding 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0022858 alanine transmembrane transporter activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0034450 ubiquitin-ubiquitin ligase activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0043023 ribosomal large subunit binding 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0055102 lipase inhibitor activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0097027 ubiquitin-protein transferase activator activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.879262986631788 GO:0005507 copper ion binding 3/788 63/18639 0.0476190476190476 1.12635968092821 0.501188730174834 0.881241438849847 GO:0050997 quaternary ammonium group binding 2/788 40/18639 0.05 1.18267766497462 0.508854382294558 0.881442113125702 GO:0019887 protein kinase regulator activity 11/788 255/18639 0.0431372549019608 1.02034935801732 0.516361410520562 0.881442113125702 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0008484 sulfuric ester hydrolase activity 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0016018 cyclosporin A binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0017110 nucleoside diphosphate phosphatase activity 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0030169 low-density lipoprotein particle binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0031489 myosin V binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0048038 quinone binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0070402 NADPH binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0070403 NAD+ binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.881442113125702 GO:0001530 lipopolysaccharide binding 2/788 41/18639 0.0487804878048781 1.15383186826792 0.522133000906485 0.881442113125702 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/788 41/18639 0.0487804878048781 1.15383186826792 0.522133000906485 0.881442113125702 GO:0019843 rRNA binding 3/788 65/18639 0.0461538461538462 1.09170245997657 0.522275196821016 0.881442113125702 GO:0038024 cargo receptor activity 3/788 65/18639 0.0461538461538462 1.09170245997657 0.522275196821016 0.881442113125702 GO:1901981 phosphatidylinositol phosphate binding 8/788 185/18639 0.0432432432432432 1.02285635889697 0.524917880009217 0.881442113125702 GO:0004402 histone acetyltransferase activity 2/788 42/18639 0.0476190476190476 1.12635968092821 0.53516836619219 0.881442113125702 GO:0004520 DNA endonuclease activity 2/788 42/18639 0.0476190476190476 1.12635968092821 0.53516836619219 0.881442113125702 GO:0019894 kinesin binding 2/788 42/18639 0.0476190476190476 1.12635968092821 0.53516836619219 0.881442113125702 GO:0031492 nucleosomal DNA binding 2/788 42/18639 0.0476190476190476 1.12635968092821 0.53516836619219 0.881442113125702 GO:0043175 RNA polymerase core enzyme binding 2/788 42/18639 0.0476190476190476 1.12635968092821 0.53516836619219 0.881442113125702 GO:0003924 GTPase activity 14/788 331/18639 0.0422960725075529 1.0004524054166 0.538088936556663 0.881442113125702 GO:0000400 four-way junction DNA binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0000900 mRNA regulatory element binding translation repressor activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0003746 translation elongation factor activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0004706 JUN kinase kinase kinase activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0005372 water transmembrane transporter activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0008308 voltage-gated monoatomic anion channel activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0008525 phosphatidylcholine transporter activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0015172 acidic amino acid transmembrane transporter activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0015373 monoatomic anion:sodium symporter activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0016854 racemase and epimerase activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0017075 syntaxin-1 binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0022851 GABA-gated chloride ion channel activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0031690 adrenergic receptor binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0032393 MHC class I receptor activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0034185 apolipoprotein binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0035615 clathrin adaptor activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0070064 proline-rich region binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:1901611 phosphatidylglycerol binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:1990381 ubiquitin-specific protease binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.881442113125702 GO:0035091 phosphatidylinositol binding 12/788 284/18639 0.0422535211267606 0.999445914063058 0.542521963125962 0.881442113125702 GO:0046943 carboxylic acid transmembrane transporter activity 8/788 188/18639 0.0425531914893617 1.00653418295712 0.543309911715153 0.881442113125702 GO:0008375 acetylglucosaminyltransferase activity 2/788 43/18639 0.0465116279069767 1.10016526974383 0.547957291532043 0.881442113125702 GO:0052689 carboxylic ester hydrolase activity 4/788 92/18639 0.0434782608695652 1.02841536084749 0.548935193744263 0.881442113125702 GO:0005342 organic acid transmembrane transporter activity 8/788 189/18639 0.0423280423280423 1.00120860526952 0.549378216641814 0.881442113125702 GO:0015103 inorganic anion transmembrane transporter activity 7/788 165/18639 0.0424242424242424 1.0034840793724 0.550454543641067 0.881442113125702 GO:1990782 protein tyrosine kinase binding 5/788 117/18639 0.0427350427350427 1.01083561108942 0.554200267145641 0.881442113125702 GO:0019902 phosphatase binding 8/788 190/18639 0.0421052631578947 0.995939086294416 0.555413504524783 0.881442113125702 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0004890 GABA-A receptor activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0005520 insulin-like growth factor binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0008301 DNA binding, bending 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0015245 fatty acid transmembrane transporter activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0030506 ankyrin binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0031420 alkali metal ion binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0042834 peptidoglycan binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0046624 sphingolipid transporter activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:1990380 K48-linked deubiquitinase activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.881442113125702 GO:0001223 transcription coactivator binding 2/788 44/18639 0.0454545454545455 1.07516151361329 0.560497293341213 0.881442113125702 GO:0016790 thiolester hydrolase activity 2/788 44/18639 0.0454545454545455 1.07516151361329 0.560497293341213 0.881442113125702 GO:0019205 nucleobase-containing compound kinase activity 2/788 44/18639 0.0454545454545455 1.07516151361329 0.560497293341213 0.881442113125702 GO:0008080 N-acetyltransferase activity 3/788 69/18639 0.0434782608695652 1.02841536084749 0.562930746392546 0.88381054581894 GO:0019955 cytokine binding 6/788 144/18639 0.0416666666666667 0.985564720812183 0.572713303759767 0.886406272505974 GO:0042605 peptide antigen binding 2/788 45/18639 0.0444444444444444 1.05126903553299 0.572786537458671 0.886406272505974 GO:0032182 ubiquitin-like protein binding 5/788 120/18639 0.0416666666666667 0.985564720812183 0.576865254374008 0.886406272505974 GO:0005326 neurotransmitter transmembrane transporter activity 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0010851 cyclase regulator activity 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0016408 C-acyltransferase activity 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0030742 GTP-dependent protein binding 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0043024 ribosomal small subunit binding 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0052745 inositol phosphate phosphatase activity 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0140664 ATP-dependent DNA damage sensor activity 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.886406272505974 GO:0004540 RNA nuclease activity 5/788 121/18639 0.0413223140495868 0.977419557830264 0.584283745763177 0.886406272505974 GO:0015108 chloride transmembrane transporter activity 5/788 121/18639 0.0413223140495868 0.977419557830264 0.584283745763177 0.886406272505974 GO:0051082 unfolded protein binding 5/788 121/18639 0.0413223140495868 0.977419557830264 0.584283745763177 0.886406272505974 GO:0005248 voltage-gated sodium channel activity 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.886406272505974 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.886406272505974 GO:0019200 carbohydrate kinase activity 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.886406272505974 GO:0035613 RNA stem-loop binding 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.886406272505974 GO:0036122 BMP binding 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.886406272505974 GO:0070182 DNA polymerase binding 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.886406272505974 GO:0140312 cargo adaptor activity 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.886406272505974 GO:0005504 fatty acid binding 2/788 47/18639 0.0425531914893617 1.00653418295712 0.596608364116192 0.886406272505974 GO:0061733 protein-lysine-acetyltransferase activity 2/788 47/18639 0.0425531914893617 1.00653418295712 0.596608364116192 0.886406272505974 GO:0140359 ABC-type transporter activity 2/788 47/18639 0.0425531914893617 1.00653418295712 0.596608364116192 0.886406272505974 GO:0043539 protein serine/threonine kinase activator activity 3/788 73/18639 0.0410958904109589 0.972063834225714 0.601409900856622 0.886406272505974 GO:0008509 monoatomic anion transmembrane transporter activity 6/788 149/18639 0.0402684563758389 0.95249207917419 0.606173154551024 0.886406272505974 GO:0032266 phosphatidylinositol-3-phosphate binding 2/788 48/18639 0.0416666666666667 0.985564720812183 0.608140087621778 0.886406272505974 GO:0038187 pattern recognition receptor activity 2/788 48/18639 0.0416666666666667 0.985564720812183 0.608140087621778 0.886406272505974 GO:0004407 histone deacetylase activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0008093 cytoskeletal anchor activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0015377 chloride:monoatomic cation symporter activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0016881 acid-amino acid ligase activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0033558 protein lysine deacetylase activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0061133 endopeptidase activator activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0070034 telomerase RNA binding 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0140784 metal ion sensor activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.886406272505974 GO:0005004 GPI-linked ephrin receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0005008 hepatocyte growth factor receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0005009 insulin receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0005011 macrophage colony-stimulating factor receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0005020 stem cell factor receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0008288 boss receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0016763 pentosyltransferase activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0036332 placental growth factor receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0038062 protein tyrosine kinase collagen receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0060175 brain-derived neurotrophic factor receptor activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.886406272505974 GO:0044183 protein folding chaperone 3/788 75/18639 0.04 0.946142131979696 0.619792567840536 0.886406272505974 GO:0051536 iron-sulfur cluster binding 3/788 76/18639 0.0394736842105263 0.933692893401015 0.628764937338251 0.886406272505974 GO:0003887 DNA-directed DNA polymerase activity 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.886406272505974 GO:0005212 structural constituent of eye lens 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.886406272505974 GO:0008171 O-methyltransferase activity 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.886406272505974 GO:0016493 C-C chemokine receptor activity 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.886406272505974 GO:0016917 GABA receptor activity 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.886406272505974 GO:0031681 G-protein beta-subunit binding 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.886406272505974 GO:0099186 structural constituent of postsynapse 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.886406272505974 GO:0005006 epidermal growth factor receptor activity 2/788 50/18639 0.04 0.946142131979696 0.630446566607755 0.886406272505974 GO:0005007 fibroblast growth factor receptor activity 2/788 50/18639 0.04 0.946142131979696 0.630446566607755 0.886406272505974 GO:0005017 platelet-derived growth factor receptor activity 2/788 50/18639 0.04 0.946142131979696 0.630446566607755 0.886406272505974 GO:0005019 platelet-derived growth factor beta-receptor activity 2/788 50/18639 0.04 0.946142131979696 0.630446566607755 0.886406272505974 GO:0048020 CCR chemokine receptor binding 2/788 50/18639 0.04 0.946142131979696 0.630446566607755 0.886406272505974 GO:0015171 amino acid transmembrane transporter activity 4/788 102/18639 0.0392156862745098 0.92759032547029 0.630765897315023 0.886406272505974 GO:0003774 cytoskeletal motor activity 6/788 153/18639 0.0392156862745098 0.92759032547029 0.631878591949864 0.886406272505974 GO:0031490 chromatin DNA binding 5/788 128/18639 0.0390625 0.923966925761421 0.634160108789262 0.886406272505974 GO:0051540 metal cluster binding 3/788 77/18639 0.038961038961039 0.921567011668534 0.637590121156912 0.886406272505974 GO:0003743 translation initiation factor activity 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0005010 insulin-like growth factor receptor activity 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0005021 vascular endothelial growth factor receptor activity 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0005030 neurotrophin receptor activity 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0005048 signal sequence binding 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0005272 sodium channel activity 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0016597 amino acid binding 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0016830 carbon-carbon lyase activity 2/788 51/18639 0.0392156862745098 0.92759032547029 0.641223146542661 0.886406272505974 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0004622 lysophospholipase activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0005540 hyaluronic acid binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0015295 solute:proton symporter activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0019957 C-C chemokine binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0048027 mRNA 5'-UTR binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0140612 DNA damage sensor activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.886406272505974 GO:0016298 lipase activity 5/788 130/18639 0.0384615384615385 0.909752049980477 0.64771741458475 0.886406272505974 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/788 181/18639 0.0386740331491713 0.914778304400258 0.648122517224103 0.886406272505974 GO:0140375 immune receptor activity 6/788 156/18639 0.0384615384615385 0.909752049980477 0.650499384097146 0.886406272505974 GO:0031072 heat shock protein binding 5/788 131/18639 0.0381679389312977 0.902807377843221 0.654376135202965 0.886406272505974 GO:0000030 mannosyltransferase activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0004709 MAP kinase kinase kinase activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0015645 fatty acid ligase activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0015662 P-type ion transporter activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0017025 TBP-class protein binding 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0120515 fatty acid-CoA ligase activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0140358 P-type transmembrane transporter activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.886406272505974 GO:0008013 beta-catenin binding 4/788 106/18639 0.0377358490566038 0.892586916961977 0.660695545542102 0.886406272505974 GO:0005003 ephrin receptor activity 2/788 53/18639 0.0377358490566038 0.892586916961977 0.662030273266281 0.886406272505974 GO:0005005 transmembrane-ephrin receptor activity 2/788 53/18639 0.0377358490566038 0.892586916961977 0.662030273266281 0.886406272505974 GO:0005544 calcium-dependent phospholipid binding 2/788 53/18639 0.0377358490566038 0.892586916961977 0.662030273266281 0.886406272505974 GO:0017046 peptide hormone binding 2/788 53/18639 0.0377358490566038 0.892586916961977 0.662030273266281 0.886406272505974 GO:0038064 collagen receptor activity 2/788 53/18639 0.0377358490566038 0.892586916961977 0.662030273266281 0.886406272505974 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/788 53/18639 0.0377358490566038 0.892586916961977 0.662030273266281 0.886406272505974 GO:0004518 nuclease activity 8/788 209/18639 0.0382775119617225 0.90539916935856 0.662609194422205 0.886406272505974 GO:0000049 tRNA binding 3/788 80/18639 0.0375 0.887008248730964 0.663176990867534 0.886406272505974 GO:0003925 G protein activity 2/788 54/18639 0.037037037037037 0.876057529610829 0.672064689769593 0.890852793510798 GO:0001637 G protein-coupled chemoattractant receptor activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0004950 chemokine receptor activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0005112 Notch binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0005227 calcium-activated cation channel activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0034237 protein kinase A regulatory subunit binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0051139 metal cation:proton antiporter activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0097602 cullin family protein binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0120014 phospholipid transfer activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.890852793510798 GO:0042578 phosphoric ester hydrolase activity 14/788 363/18639 0.0385674931129477 0.912258253974913 0.675851594657195 0.890852793510798 GO:0031406 carboxylic acid binding 7/788 187/18639 0.0374331550802139 0.885427128858004 0.681334670279778 0.895291356676218 GO:0008374 O-acyltransferase activity 2/788 55/18639 0.0363636363636364 0.860129210890632 0.681856050508362 0.895291356676218 GO:0004620 phospholipase activity 4/788 109/18639 0.036697247706422 0.868020304568528 0.682037276964254 0.895291356676218 GO:0005254 chloride channel activity 3/788 83/18639 0.036144578313253 0.854947709620207 0.687426736888277 0.896685102909086 GO:0008135 translation factor activity, RNA binding 3/788 83/18639 0.036144578313253 0.854947709620207 0.687426736888277 0.896685102909086 GO:0005044 scavenger receptor activity 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.896685102909086 GO:0008266 poly(U) RNA binding 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.896685102909086 GO:0016405 CoA-ligase activity 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.896685102909086 GO:0023026 MHC class II protein complex binding 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.896685102909086 GO:0030170 pyridoxal phosphate binding 2/788 56/18639 0.0357142857142857 0.844769760696157 0.691406943663739 0.898407900428166 GO:0043177 organic acid binding 7/788 189/18639 0.037037037037037 0.876057529610829 0.691953199280456 0.898407900428166 GO:0180051 translation factor activity 3/788 84/18639 0.0357142857142857 0.844769760696157 0.695213466169572 0.901412834366806 GO:0070279 vitamin B6 binding 2/788 57/18639 0.0350877192982456 0.82994923857868 0.700720173005541 0.903383003775155 GO:0036408 histone H3K14 acetyltransferase activity 1/788 28/18639 0.0357142857142857 0.844769760696157 0.701922508149079 0.903383003775155 GO:0046966 nuclear thyroid hormone receptor binding 1/788 28/18639 0.0357142857142857 0.844769760696157 0.701922508149079 0.903383003775155 GO:0050698 proteoglycan sulfotransferase activity 1/788 28/18639 0.0357142857142857 0.844769760696157 0.701922508149079 0.903383003775155 GO:0051393 alpha-actinin binding 1/788 28/18639 0.0357142857142857 0.844769760696157 0.701922508149079 0.903383003775155 GO:0005200 structural constituent of cytoskeleton 4/788 112/18639 0.0357142857142857 0.844769760696157 0.702420572714994 0.903383003775155 GO:0008514 organic anion transmembrane transporter activity 10/788 269/18639 0.0371747211895911 0.879314249051762 0.705430788704021 0.906031727270797 GO:0003785 actin monomer binding 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.911592690263297 GO:0004181 metallocarboxypeptidase activity 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.911592690263297 GO:0010484 histone H3 acetyltransferase activity 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.911592690263297 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.911592690263297 GO:0106222 lncRNA binding 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.911592690263297 GO:0001786 phosphatidylserine binding 2/788 59/18639 0.0338983050847458 0.801815366084488 0.71864579798068 0.914357838297158 GO:0070063 RNA polymerase binding 2/788 59/18639 0.0338983050847458 0.801815366084488 0.71864579798068 0.914357838297158 GO:0001965 G-protein alpha-subunit binding 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0008187 poly-pyrimidine tract binding 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0016769 transferase activity, transferring nitrogenous groups 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0022839 monoatomic ion-gated channel activity 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0043995 histone H4K5 acetyltransferase activity 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0043996 histone H4K8 acetyltransferase activity 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0043997 histone H4K12 acetyltransferase activity 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0098918 structural constituent of synapse 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.914357838297158 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/788 60/18639 0.0333333333333333 0.788451776649746 0.727264681457761 0.914357838297158 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.921642652234235 GO:0016878 acid-thiol ligase activity 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.921642652234235 GO:0070273 phosphatidylinositol-4-phosphate binding 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.921642652234235 GO:0070325 lipoprotein particle receptor binding 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.921642652234235 GO:0072349 modified amino acid transmembrane transporter activity 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.921642652234235 GO:0019210 kinase inhibitor activity 3/788 90/18639 0.0333333333333333 0.788451776649746 0.738861475663122 0.921642652234235 GO:0072341 modified amino acid binding 3/788 91/18639 0.032967032967033 0.779787471411837 0.745632575428108 0.927371065833072 GO:0015106 bicarbonate transmembrane transporter activity 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.927371065833072 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.927371065833072 GO:0042910 xenobiotic transmembrane transporter activity 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.927371065833072 GO:0051059 NF-kappaB binding 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.927371065833072 GO:0070717 poly-purine tract binding 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.927371065833072 GO:1901682 sulfur compound transmembrane transporter activity 2/788 63/18639 0.0317460317460317 0.750906453952139 0.751787350079652 0.92925206825669 GO:0051213 dioxygenase activity 3/788 93/18639 0.032258064516129 0.763017848370722 0.758753551182331 0.934443975611067 GO:0004536 DNA nuclease activity 2/788 64/18639 0.03125 0.739173540609137 0.759529128316063 0.934443975611067 GO:0019956 chemokine binding 1/788 33/18639 0.0303030303030303 0.71677434240886 0.759909843755065 0.934443975611067 GO:0071889 14-3-3 protein binding 1/788 33/18639 0.0303030303030303 0.71677434240886 0.759909843755065 0.934443975611067 GO:0019842 vitamin binding 5/788 150/18639 0.0333333333333333 0.788451776649746 0.765171591114324 0.939701709190658 GO:0160215 deacylase activity 2/788 65/18639 0.0307692307692308 0.727801639984381 0.767060999157175 0.94080969394696 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.942085305830124 GO:0090482 vitamin transmembrane transporter activity 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.942085305830124 GO:0016887 ATP hydrolysis activity 15/788 417/18639 0.0359712230215827 0.850847240988935 0.77512436256539 0.946706902185857 GO:0015291 secondary active transmembrane transporter activity 10/788 287/18639 0.0348432055749129 0.824165620191372 0.776830921184474 0.946706902185857 GO:0016407 acetyltransferase activity 3/788 96/18639 0.03125 0.739173540609137 0.777402964244699 0.946706902185857 GO:0034061 DNA polymerase activity 1/788 35/18639 0.0285714285714286 0.675815808556925 0.77981628354239 0.946706902185857 GO:0043015 gamma-tubulin binding 1/788 35/18639 0.0285714285714286 0.675815808556925 0.77981628354239 0.946706902185857 GO:0061631 ubiquitin conjugating enzyme activity 1/788 35/18639 0.0285714285714286 0.675815808556925 0.77981628354239 0.946706902185857 GO:0050840 extracellular matrix binding 2/788 67/18639 0.0298507462686567 0.706076217895295 0.78151060543806 0.947556751886096 GO:0030145 manganese ion binding 2/788 68/18639 0.0294117647058824 0.695692744102717 0.78843624095292 0.949536448498887 GO:1990841 promoter-specific chromatin binding 2/788 68/18639 0.0294117647058824 0.695692744102717 0.78843624095292 0.949536448498887 GO:0004190 aspartic-type endopeptidase activity 1/788 36/18639 0.0277777777777778 0.657043147208122 0.789142491270222 0.949536448498887 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/788 36/18639 0.0277777777777778 0.657043147208122 0.789142491270222 0.949536448498887 GO:0055106 ubiquitin-protein transferase regulator activity 1/788 36/18639 0.0277777777777778 0.657043147208122 0.789142491270222 0.949536448498887 GO:0005216 monoatomic ion channel activity 16/788 448/18639 0.0357142857142857 0.844769760696157 0.790034507645276 0.949536448498887 GO:0019783 ubiquitin-like protein peptidase activity 4/788 127/18639 0.031496062992126 0.744993804708422 0.790117947176933 0.949536448498887 GO:0004842 ubiquitin-protein transferase activity 16/788 449/18639 0.0356347438752784 0.842888313567657 0.792828277290819 0.951593637604724 GO:0022829 wide pore channel activity 1/788 37/18639 0.027027027027027 0.639285224310605 0.798074153737516 0.953088557032396 GO:0023023 MHC protein complex binding 1/788 37/18639 0.027027027027027 0.639285224310605 0.798074153737516 0.953088557032396 GO:0030551 cyclic nucleotide binding 1/788 37/18639 0.027027027027027 0.639285224310605 0.798074153737516 0.953088557032396 GO:0070001 aspartic-type peptidase activity 1/788 37/18639 0.027027027027027 0.639285224310605 0.798074153737516 0.953088557032396 GO:0097110 scaffold protein binding 2/788 70/18639 0.0285714285714286 0.675815808556925 0.801709138289484 0.956231300112489 GO:0019787 ubiquitin-like protein transferase activity 17/788 479/18639 0.0354906054279749 0.839478927121859 0.803707104236205 0.957416087921379 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/788 130/18639 0.0307692307692308 0.727801639984381 0.804919276730866 0.95766300964359 GO:0043531 ADP binding 1/788 38/18639 0.0263157894736842 0.62246192893401 0.806627941870772 0.958090201325424 GO:0008234 cysteine-type peptidase activity 6/788 187/18639 0.0320855614973262 0.758937539021146 0.807289015387529 0.958090201325424 GO:0005525 GTP binding 13/788 378/18639 0.0343915343915344 0.813481991781484 0.813990141684262 0.962221788857717 GO:0000217 DNA secondary structure binding 1/788 39/18639 0.0256410256410256 0.606501366653651 0.814819823049517 0.962221788857717 GO:0005178 integrin binding 5/788 161/18639 0.031055900621118 0.734582400605354 0.815783303472037 0.962221788857717 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 17/788 484/18639 0.0351239669421488 0.830806624155724 0.816439066600844 0.962221788857717 GO:0004177 aminopeptidase activity 1/788 40/18639 0.025 0.59133883248731 0.822665090761183 0.962221788857717 GO:0004532 RNA exonuclease activity 1/788 40/18639 0.025 0.59133883248731 0.822665090761183 0.962221788857717 GO:0015144 carbohydrate transmembrane transporter activity 1/788 40/18639 0.025 0.59133883248731 0.822665090761183 0.962221788857717 GO:0030331 nuclear estrogen receptor binding 1/788 40/18639 0.025 0.59133883248731 0.822665090761183 0.962221788857717 GO:0140662 ATP-dependent protein folding chaperone 1/788 40/18639 0.025 0.59133883248731 0.822665090761183 0.962221788857717 GO:0051087 protein-folding chaperone binding 4/788 134/18639 0.0298507462686567 0.706076217895295 0.823323036002166 0.962221788857717 GO:0031491 nucleosome binding 2/788 74/18639 0.027027027027027 0.639285224310605 0.826053872623536 0.962221788857717 GO:0048029 monosaccharide binding 2/788 74/18639 0.027027027027027 0.639285224310605 0.826053872623536 0.962221788857717 GO:0001727 lipid kinase activity 1/788 41/18639 0.024390243902439 0.576915934133961 0.83017839300755 0.962221788857717 GO:0008227 G protein-coupled amine receptor activity 1/788 41/18639 0.024390243902439 0.576915934133961 0.83017839300755 0.962221788857717 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/788 41/18639 0.024390243902439 0.576915934133961 0.83017839300755 0.962221788857717 GO:0042169 SH2 domain binding 1/788 41/18639 0.024390243902439 0.576915934133961 0.83017839300755 0.962221788857717 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/788 41/18639 0.024390243902439 0.576915934133961 0.83017839300755 0.962221788857717 GO:0140828 metal cation:monoatomic cation antiporter activity 1/788 41/18639 0.024390243902439 0.576915934133961 0.83017839300755 0.962221788857717 GO:0140104 molecular carrier activity 8/788 249/18639 0.0321285140562249 0.759953519662406 0.831117556100449 0.962221788857717 GO:0003725 double-stranded RNA binding 2/788 75/18639 0.0266666666666667 0.630761421319797 0.831704867275125 0.962221788857717 GO:0099094 ligand-gated monoatomic cation channel activity 4/788 136/18639 0.0294117647058824 0.695692744102717 0.831973508938887 0.962221788857717 GO:0001216 DNA-binding transcription activator activity 17/788 491/18639 0.0346232179226069 0.818962130532323 0.833245057099207 0.962524290200659 GO:0051879 Hsp90 protein binding 1/788 42/18639 0.0238095238095238 0.563179840464104 0.837373759515242 0.966122509464922 GO:0004843 cysteine-type deubiquitinase activity 3/788 108/18639 0.0277777777777778 0.657043147208122 0.840456009490716 0.968506139110825 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/788 43/18639 0.0232558139534884 0.550082634871916 0.844264627800556 0.969687002618587 GO:0070851 growth factor receptor binding 4/788 139/18639 0.0287769784172662 0.680677792791148 0.844285382066055 0.969687002618587 GO:0016755 aminoacyltransferase activity 17/788 496/18639 0.0342741935483871 0.810706463893892 0.844533276152599 0.969687002618587 GO:0019199 transmembrane receptor protein kinase activity 2/788 78/18639 0.0256410256410256 0.606501366653651 0.847676726465384 0.972125054538521 GO:0001046 core promoter sequence-specific DNA binding 1/788 44/18639 0.0227272727272727 0.537580756806645 0.85086386813682 0.973437294519075 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/788 44/18639 0.0227272727272727 0.537580756806645 0.85086386813682 0.973437294519075 GO:0051539 4 iron, 4 sulfur cluster binding 1/788 45/18639 0.0222222222222222 0.525634517766497 0.857183807470414 0.979491808776145 GO:0140030 modification-dependent protein binding 5/788 173/18639 0.0289017341040462 0.683628708077815 0.860614265568074 0.980750515441076 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/788 46/18639 0.0217391304347826 0.514207680423747 0.863236252329687 0.980750515441076 GO:0030291 protein serine/threonine kinase inhibitor activity 1/788 46/18639 0.0217391304347826 0.514207680423747 0.863236252329687 0.980750515441076 GO:0019001 guanyl nucleotide binding 13/788 400/18639 0.0325 0.768740482233503 0.868578904016749 0.980750515441076 GO:0032561 guanyl ribonucleotide binding 13/788 400/18639 0.0325 0.768740482233503 0.868578904016749 0.980750515441076 GO:0061749 forked DNA-dependent helicase activity 1/788 47/18639 0.0212765957446809 0.503267091478561 0.869032510769111 0.980750515441076 GO:0099095 ligand-gated monoatomic anion channel activity 1/788 47/18639 0.0212765957446809 0.503267091478561 0.869032510769111 0.980750515441076 GO:0140938 histone H3 methyltransferase activity 1/788 47/18639 0.0212765957446809 0.503267091478561 0.869032510769111 0.980750515441076 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/788 47/18639 0.0212765957446809 0.503267091478561 0.869032510769111 0.980750515441076 GO:0017124 SH3 domain binding 3/788 115/18639 0.0260869565217391 0.617049216508497 0.869605651151846 0.980750515441076 GO:0101005 deubiquitinase activity 3/788 115/18639 0.0260869565217391 0.617049216508497 0.869605651151846 0.980750515441076 GO:0009378 four-way junction helicase activity 1/788 48/18639 0.0208333333333333 0.492782360406091 0.874583413389267 0.982803076798938 GO:0036121 double-stranded DNA helicase activity 1/788 48/18639 0.0208333333333333 0.492782360406091 0.874583413389267 0.982803076798938 GO:0043138 3'-5' DNA helicase activity 1/788 48/18639 0.0208333333333333 0.492782360406091 0.874583413389267 0.982803076798938 GO:0004860 protein kinase inhibitor activity 2/788 84/18639 0.0238095238095238 0.563179840464104 0.875550694860754 0.982803076798938 GO:0061630 ubiquitin protein ligase activity 11/788 353/18639 0.0311614730878187 0.737079564573417 0.885337347628359 0.992619402693913 GO:0004197 cysteine-type endopeptidase activity 2/788 88/18639 0.0227272727272727 0.537580756806645 0.891436905270576 0.99828363187175 GO:0003727 single-stranded RNA binding 2/788 89/18639 0.0224719101123595 0.531540523584099 0.895103310545566 0.999999408753233 GO:0015276 ligand-gated monoatomic ion channel activity 5/788 186/18639 0.0268817204301075 0.635848206975602 0.898489592274203 0.999999408753233 GO:0008146 sulfotransferase activity 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.999999408753233 GO:0051018 protein kinase A binding 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.999999408753233 GO:0140463 chromatin-protein adaptor activity 1/788 54/18639 0.0185185185185185 0.438028764805415 0.903287611408769 0.999999408753233 GO:0022834 ligand-gated channel activity 5/788 188/18639 0.0265957446808511 0.629083864348202 0.90344673441405 0.999999408753233 GO:0140597 protein carrier chaperone 5/788 188/18639 0.0265957446808511 0.629083864348202 0.90344673441405 0.999999408753233 GO:0008276 protein methyltransferase activity 2/788 95/18639 0.0210526315789474 0.497969543147208 0.914786742103926 0.999999408753233 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/788 57/18639 0.0175438596491228 0.41497461928934 0.915075751919657 0.999999408753233 GO:0005261 monoatomic cation channel activity 10/788 341/18639 0.0293255131964809 0.693652589427929 0.915562860335228 0.999999408753233 GO:0017116 single-stranded DNA helicase activity 1/788 58/18639 0.0172413793103448 0.407819884474007 0.918677103092152 0.999999408753233 GO:0061980 regulatory RNA binding 1/788 58/18639 0.0172413793103448 0.407819884474007 0.918677103092152 0.999999408753233 GO:0061659 ubiquitin-like protein ligase activity 11/788 372/18639 0.0295698924731183 0.699433027673162 0.919520493545622 0.999999408753233 GO:0030594 neurotransmitter receptor activity 2/788 97/18639 0.0206185567010309 0.487702129886441 0.920538422595377 0.999999408753233 GO:0008170 N-methyltransferase activity 2/788 98/18639 0.0204081632653061 0.482725577540661 0.923275353803661 0.999999408753233 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/788 60/18639 0.0166666666666667 0.394225888324873 0.925428651532095 0.999999408753233 GO:0004175 endopeptidase activity 12/788 405/18639 0.0296296296296296 0.700846023688663 0.926226759285213 0.999999408753233 GO:0015026 coreceptor activity 1/788 61/18639 0.0163934426229508 0.387763168844137 0.928591481748614 0.999999408753233 GO:0016779 nucleotidyltransferase activity 3/788 136/18639 0.0220588235294118 0.521769558077038 0.93076558471858 0.999999408753233 GO:0022824 transmitter-gated monoatomic ion channel activity 1/788 63/18639 0.0158730158730159 0.37545322697607 0.934520860269704 0.999999408753233 GO:0022835 transmitter-gated channel activity 1/788 63/18639 0.0158730158730159 0.37545322697607 0.934520860269704 0.999999408753233 GO:0140767 enzyme-substrate adaptor activity 3/788 139/18639 0.0215827338129496 0.510508344593361 0.936941396421102 0.999999408753233 GO:0008235 metalloexopeptidase activity 1/788 66/18639 0.0151515151515152 0.35838717120443 0.942505723563014 0.999999408753233 GO:0042054 histone methyltransferase activity 1/788 67/18639 0.0149253731343284 0.353038108947648 0.944945043534604 0.999999408753233 GO:0046873 metal ion transmembrane transporter activity 13/788 450/18639 0.0288888888888889 0.683324873096447 0.945996588156439 0.999999408753233 GO:0019903 protein phosphatase binding 3/788 144/18639 0.0208333333333333 0.492782360406091 0.946114706913826 0.999999408753233 GO:0140223 general transcription initiation factor activity 1/788 68/18639 0.0147058823529412 0.347846372051359 0.947280995811943 0.999999408753233 GO:0002039 p53 binding 1/788 69/18639 0.0144927536231884 0.342805120282498 0.949517955334865 0.999999408753233 GO:0016279 protein-lysine N-methyltransferase activity 1/788 69/18639 0.0144927536231884 0.342805120282498 0.949517955334865 0.999999408753233 GO:0004222 metalloendopeptidase activity 2/788 110/18639 0.0181818181818182 0.430064605445316 0.949882192571735 0.999999408753233 GO:0015085 calcium ion transmembrane transporter activity 3/788 147/18639 0.0204081632653061 0.482725577540661 0.951006953664909 0.999999408753233 GO:0016278 lysine N-methyltransferase activity 1/788 70/18639 0.0142857142857143 0.337907904278463 0.951660112103639 0.999999408753233 GO:0030246 carbohydrate binding 7/788 280/18639 0.025 0.59133883248731 0.954435082787934 0.999999408753233 GO:0000510 H3-H4 histone complex chaperone activity 3/788 151/18639 0.0198675496688742 0.469938145023028 0.956887296670027 0.999999408753233 GO:0140584 chromatin extrusion motor activity 3/788 151/18639 0.0198675496688742 0.469938145023028 0.956887296670027 0.999999408753233 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/788 151/18639 0.0198675496688742 0.469938145023028 0.956887296670027 0.999999408753233 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/788 151/18639 0.0198675496688742 0.469938145023028 0.956887296670027 0.999999408753233 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/788 73/18639 0.0136986301369863 0.324021278075238 0.957557053477836 0.999999408753233 GO:0035401 histone H3Y41 kinase activity 2/788 115/18639 0.0173913043478261 0.411366144338998 0.958139963959381 0.999999408753233 GO:0140801 histone H2AXY142 kinase activity 2/788 115/18639 0.0173913043478261 0.411366144338998 0.958139963959381 0.999999408753233 GO:0015616 DNA translocase activity 3/788 152/18639 0.0197368421052632 0.466846446700508 0.958250529423615 0.999999408753233 GO:0140674 ATP-dependent histone chaperone activity 3/788 152/18639 0.0197368421052632 0.466846446700508 0.958250529423615 0.999999408753233 GO:0003678 DNA helicase activity 1/788 74/18639 0.0135135135135135 0.319642612155303 0.959358466914197 0.999999408753233 GO:0035064 methylated histone binding 1/788 74/18639 0.0135135135135135 0.319642612155303 0.959358466914197 0.999999408753233 GO:0061775 cohesin loader activity 3/788 153/18639 0.0196078431372549 0.463795162735145 0.959573280842813 0.999999408753233 GO:0022836 gated channel activity 8/788 318/18639 0.0251572327044025 0.595057944641318 0.961557379624405 0.999999408753233 GO:0140034 methylation-dependent protein binding 1/788 76/18639 0.0131578947368421 0.311230964467005 0.962735432695455 0.999999408753233 GO:0140658 ATP-dependent chromatin remodeler activity 3/788 158/18639 0.0189873417721519 0.449118100623273 0.965617034776594 0.999999408753233 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/788 122/18639 0.0163934426229508 0.387763168844137 0.96754118989961 0.999999408753233 GO:0003689 DNA clamp loader activity 3/788 160/18639 0.01875 0.443504124365482 0.967787397320418 0.999999408753233 GO:0140713 histone chaperone activity 3/788 164/18639 0.0182926829268293 0.43268695060047 0.97174592190084 0.999999408753233 GO:0042826 histone deacetylase binding 2/788 127/18639 0.015748031496063 0.372496902354211 0.972974879417773 0.999999408753233 GO:0004527 exonuclease activity 1/788 84/18639 0.0119047619047619 0.281589920232052 0.973663467678488 0.999999408753233 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/788 167/18639 0.0179640718562874 0.424914131128606 0.97440768241617 0.999999408753233 GO:0008168 methyltransferase activity 4/788 204/18639 0.0196078431372549 0.463795162735145 0.975201808730518 0.999999408753233 GO:0005262 calcium channel activity 2/788 131/18639 0.0152671755725191 0.361122951137288 0.976679046470678 0.999999408753233 GO:0008081 phosphoric diester hydrolase activity 1/788 87/18639 0.0114942528735632 0.271879922982671 0.976878558416905 0.999999408753233 GO:0008094 ATP-dependent activity, acting on DNA 4/788 210/18639 0.019047619047619 0.450543872371284 0.979372403292537 0.999999408753233 GO:0003823 antigen binding 3/788 174/18639 0.0172413793103448 0.407819884474007 0.979722953463698 0.999999408753233 GO:0015297 antiporter activity 2/788 135/18639 0.0148148148148148 0.350423011844332 0.97988991112924 0.999999408753233 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/788 91/18639 0.010989010989011 0.259929157137279 0.980563914887852 0.999999408753233 GO:0016741 transferase activity, transferring one-carbon groups 4/788 215/18639 0.0186046511627907 0.440066107897533 0.982333484868737 0.999999408753233 GO:0140101 catalytic activity, acting on a tRNA 2/788 139/18639 0.0143884892086331 0.340338896395574 0.98267052369306 0.999999408753233 GO:0004713 protein tyrosine kinase activity 2/788 140/18639 0.0142857142857143 0.337907904278463 0.98330510713254 0.999999408753233 GO:0008237 metallopeptidase activity 3/788 184/18639 0.016304347826087 0.385655760317811 0.985523722384758 0.999999408753233 GO:0003730 mRNA 3'-UTR binding 5/788 262/18639 0.0190839694656489 0.45140368892161 0.987527695789197 0.999999408753233 GO:0004674 protein serine/threonine kinase activity 10/788 433/18639 0.023094688221709 0.546271438787353 0.989060042718133 0.999999408753233 GO:0140097 catalytic activity, acting on DNA 7/788 336/18639 0.0208333333333333 0.492782360406091 0.989291869942016 0.999999408753233 GO:0004386 helicase activity 2/788 155/18639 0.0129032258064516 0.305207139348289 0.990503405728379 0.999999408753233 GO:0106310 protein serine kinase activity 7/788 361/18639 0.0193905817174515 0.458656158161902 0.994658051540493 0.999999408753233 GO:0022832 voltage-gated channel activity 2/788 175/18639 0.0114285714285714 0.27032632342277 0.995576496956357 0.999999408753233 GO:0140098 catalytic activity, acting on RNA 7/788 387/18639 0.0180878552971576 0.427842049344823 0.99747724183071 0.999999408753233 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/788 243/18639 0.0123456790123457 0.292019176536943 0.998180000805965 0.999999408753233 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0004711 ribosomal protein S6 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0035175 histone H3S10 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0035979 histone H2AXS139 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0044022 histone H3S28 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0044023 histone H4S1 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0044024 histone H2AS1 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0044025 histone H2BS14 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0072354 histone H3T3 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0072371 histone H2AS121 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0140823 histone H2BS36 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0140855 histone H3S57 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0140995 histone H2A kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0140997 histone H4 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0140998 histone H2B kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:1990244 histone H2AT120 kinase activity 3/788 245/18639 0.0122448979591837 0.289635346524397 0.998307147543063 0.999999408753233 GO:0004677 DNA-dependent protein kinase activity 3/788 246/18639 0.0121951219512195 0.28845796706698 0.998367423290265 0.999999408753233 GO:0140857 histone H3T45 kinase activity 3/788 246/18639 0.0121951219512195 0.28845796706698 0.998367423290265 0.999999408753233 GO:0035402 histone H3T11 kinase activity 3/788 247/18639 0.0121457489878543 0.287290121046466 0.998425599489191 0.999999408753233 GO:0035403 histone H3T6 kinase activity 3/788 247/18639 0.0121457489878543 0.287290121046466 0.998425599489191 0.999999408753233 GO:0042393 histone binding 3/788 247/18639 0.0121457489878543 0.287290121046466 0.998425599489191 0.999999408753233 GO:0004679 AMP-activated protein kinase activity 3/788 248/18639 0.0120967741935484 0.286131693139021 0.998481747272749 0.999999408753233 GO:0141003 histone H2AX kinase activity 5/788 354/18639 0.0141242937853107 0.334089735868536 0.99932424528348 0.999999408753233 GO:0140996 histone H3 kinase activity 5/788 357/18639 0.0140056022408964 0.331282259096532 0.99938856462469 0.999999408753233 GO:0035173 histone kinase activity 5/788 360/18639 0.0138888888888889 0.328521573604061 0.999446908036136 0.999999408753233 GO:0005244 voltage-gated monoatomic ion channel activity 1/788 173/18639 0.00578034682080925 0.136725741615563 0.999451584208921 0.999999408753233 GO:0045182 translation regulator activity 2/788 356/18639 0.00561797752808989 0.132885130896025 0.999996931822889 0.999999408753233 GO:0030371 translation repressor activity 1/788 329/18639 0.00303951367781155 0.0718952987826516 0.999999408753233 0.999999408753233