ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005085 guanyl-nucleotide exchange factor activity 82/3682 230/18639 0.356521739130435 1.80478237252911 1.12375235534697e-08 1.50582815616495e-05 GO:0060589 nucleoside-triphosphatase regulator activity 145/3682 490/18639 0.295918367346939 1.49799631965768 8.63078565909774e-08 4.42904973632653e-05 GO:0044389 ubiquitin-like protein ligase binding 103/3682 322/18639 0.319875776397516 1.61927338301828 1.10477600353773e-07 4.42904973632653e-05 GO:0030695 GTPase regulator activity 144/3682 489/18639 0.294478527607362 1.49070757090538 1.32210439890344e-07 4.42904973632653e-05 GO:0031625 ubiquitin protein ligase binding 97/3682 302/18639 0.321192052980132 1.62593663104201 2.06604595869879e-07 5.53700316931276e-05 GO:0022853 active monoatomic ion transmembrane transporter activity 47/3682 118/18639 0.398305084745763 2.01629779320377 3.88527775728335e-07 8.67712032459947e-05 GO:0140297 DNA-binding transcription factor binding 139/3682 488/18639 0.284836065573771 1.44189555302268 1.69679885971382e-06 0.000324815781716645 GO:0070411 I-SMAD binding 12/3682 16/18639 0.75 3.79664584464965 2.84309781972738e-06 0.000476218884804336 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 30/3682 68/18639 0.441176470588235 2.23332108508803 4.18961611917726e-06 0.000560662637086325 GO:0004721 phosphoprotein phosphatase activity 60/3682 175/18639 0.342857142857143 1.7356095289827 4.25061624714198e-06 0.000560662637086325 GO:0016791 phosphatase activity 85/3682 273/18639 0.311355311355311 1.57614113208899 4.60514935014688e-06 0.000560662637086325 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 34/3682 82/18639 0.414634146341463 2.09895867834289 5.3539731520497e-06 0.000560662637086325 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 47/3682 128/18639 0.3671875 1.85877452810972 5.70903062580641e-06 0.000560662637086325 GO:0051020 GTPase binding 95/3682 315/18639 0.301587301587302 1.5266935671607 5.90110721657976e-06 0.000560662637086325 GO:0031267 small GTPase binding 87/3682 283/18639 0.307420494699647 1.5562223250154 6.27607429574245e-06 0.000560662637086325 GO:0015399 primary active transmembrane transporter activity 57/3682 166/18639 0.343373493975904 1.73822339875526 6.92733709714987e-06 0.000580106364157016 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 34/3682 83/18639 0.409638554216867 2.07367001956768 7.35955835124573e-06 0.000580106364157016 GO:0009055 electron transfer activity 43/3682 116/18639 0.370689655172414 1.87650311861994 1.06444121227135e-05 0.000590050555670386 GO:0033192 calmodulin-dependent protein phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:0140791 histone H2AXS140 phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:1990439 MAP kinase serine/threonine phosphatase activity 33/3682 81/18639 0.407407407407407 2.06237552055043 1.14487421249478e-05 0.000590050555670386 GO:0003779 actin binding 124/3682 443/18639 0.279909706546275 1.41695736564802 1.5006800792694e-05 0.000723800044262921 GO:0033549 MAP kinase phosphatase activity 33/3682 82/18639 0.402439024390244 2.0372245995681 1.55533824536341e-05 0.000723800044262921 GO:0140789 histone phosphatase activity 48/3682 136/18639 0.352941176470588 1.78665686807042 1.56643293161378e-05 0.000723800044262921 GO:0003712 transcription coregulator activity 136/3682 495/18639 0.274747474747475 1.39082514443731 1.63926355012689e-05 0.000732204385723342 GO:0045296 cadherin binding 97/3682 334/18639 0.290419161676647 1.4701582711817 2.60367108790428e-05 0.00112545782509411 GO:0017018 myosin phosphatase activity 33/3682 84/18639 0.392857142857143 1.98871925195934 2.80317127413571e-05 0.00117382797104433 GO:0004722 protein serine/threonine phosphatase activity 38/3682 103/18639 0.368932038834951 1.86760572293445 3.82417910501958e-05 0.00155284848506856 GO:0000995 RNA polymerase III general transcription initiation factor activity 9/3682 12/18639 0.75 3.79664584464965 5.57277163715436e-05 0.00219632764523142 GO:0031386 protein tag activity 10/3682 15/18639 0.666666666666667 3.37479630635524 0.00010065600764325 0.00374664028449876 GO:0141047 molecular tag activity 10/3682 15/18639 0.666666666666667 3.37479630635524 0.00010065600764325 0.00374664028449876 GO:0019787 ubiquitin-like protein transferase activity 127/3682 479/18639 0.265135699373695 1.34216846839389 0.000168856721426353 0.0061153515327382 GO:0140416 transcription regulator inhibitor activity 16/3682 33/18639 0.484848484848485 2.4543973137129 0.000192591591968926 0.00679138771679897 GO:0035925 mRNA 3'-UTR AU-rich region binding 15/3682 30/18639 0.5 2.53109722976643 0.000197660088131214 0.006791397899893 GO:0004842 ubiquitin-protein transferase activity 119/3682 449/18639 0.265033407572383 1.34165064740403 0.000270694955123316 0.0090682809966311 GO:0008474 palmitoyl-(protein) hydrolase activity 9/3682 14/18639 0.642857142857143 3.25426786684255 0.000344273260670176 0.010983956411858 GO:0098599 palmitoyl hydrolase activity 9/3682 14/18639 0.642857142857143 3.25426786684255 0.000344273260670176 0.010983956411858 GO:0016755 aminoacyltransferase activity 129/3682 496/18639 0.26008064516129 1.31657880096722 0.000358766380508913 0.0111801616251615 GO:0004725 protein tyrosine phosphatase activity 34/3682 98/18639 0.346938775510204 1.75627154718487 0.00037114743225038 0.011303126345807 GO:0015078 proton transmembrane transporter activity 56/3682 185/18639 0.302702702702703 1.53233994450724 0.000402439194363668 0.0119534622182326 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 95/3682 349/18639 0.272206303724928 1.37796124256625 0.000410342732864702 0.0119534622182326 GO:0042578 phosphoric ester hydrolase activity 98/3682 363/18639 0.269972451790634 1.36665304968105 0.000457655395322369 0.0128136974457585 GO:0051117 ATPase binding 30/3682 84/18639 0.357142857142857 1.80792659269031 0.000458998117460005 0.0128136974457585 GO:0001221 transcription coregulator binding 38/3682 115/18639 0.330434782608696 1.67272512575869 0.000525612346424566 0.0141284449703526 GO:0005160 transforming growth factor beta receptor binding 13/3682 26/18639 0.5 2.53109722976643 0.000527180782475843 0.0141284449703526 GO:0003713 transcription coactivator activity 72/3682 256/18639 0.28125 1.42374219174362 0.000736178881350848 0.0193427392354929 GO:0031434 mitogen-activated protein kinase kinase binding 7/3682 10/18639 0.7 3.543536121673 0.000795950115201499 0.0205110221994232 GO:0001784 phosphotyrosine residue binding 19/3682 47/18639 0.404255319148936 2.04641903683243 0.000897903312130176 0.0227017063821592 GO:0003954 NADH dehydrogenase activity 18/3682 44/18639 0.409090909090909 2.07089773344526 0.00103153673118216 0.0255973929589646 GO:0008137 NADH dehydrogenase (ubiquinone) activity 17/3682 41/18639 0.414634146341463 2.09895867834289 0.0011804805322732 0.0287607984226562 GO:0045309 protein phosphorylated amino acid binding 22/3682 59/18639 0.372881355932203 1.8875979340631 0.00132226407880134 0.030690390182596 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 30/3682 89/18639 0.337078651685393 1.70635768298861 0.00135676753394514 0.030690390182596 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 30/3682 89/18639 0.337078651685393 1.70635768298861 0.00135676753394514 0.030690390182596 GO:0004709 MAP kinase kinase kinase activity 12/3682 25/18639 0.48 2.42985334057577 0.00136472743276503 0.030690390182596 GO:0004407 histone deacetylase activity 11/3682 22/18639 0.5 2.53109722976643 0.00142000312785146 0.030690390182596 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 11/3682 22/18639 0.5 2.53109722976643 0.00142000312785146 0.030690390182596 GO:0033558 protein lysine deacetylase activity 11/3682 22/18639 0.5 2.53109722976643 0.00142000312785146 0.030690390182596 GO:0001222 transcription corepressor binding 19/3682 49/18639 0.387755102040816 1.96289172920662 0.00162022227837423 0.0344618706828804 GO:0140793 histone H2AXY142 phosphatase activity 30/3682 90/18639 0.333333333333333 1.68739815317762 0.00165646769248932 0.0345879782877968 GO:0001098 basal transcription machinery binding 22/3682 60/18639 0.366666666666667 1.85613796849538 0.00170358699029447 0.0345879782877968 GO:0001099 basal RNA polymerase II transcription machinery binding 22/3682 60/18639 0.366666666666667 1.85613796849538 0.00170358699029447 0.0345879782877968 GO:0005114 type II transforming growth factor beta receptor binding 7/3682 11/18639 0.636363636363636 3.22139647424819 0.00181492661988435 0.0362985323976871 GO:0051015 actin filament binding 59/3682 209/18639 0.282296650717703 1.42904054120784 0.00190992146423 0.0376366876774735 GO:0098847 sequence-specific single stranded DNA binding 8/3682 14/18639 0.571428571428571 2.89268254830449 0.00219676564130156 0.0426618254977405 GO:0015095 magnesium ion transmembrane transporter activity 10/3682 20/18639 0.5 2.53109722976643 0.00234183933434201 0.0439827313150667 GO:0032977 membrane insertase activity 9/3682 17/18639 0.529411764705882 2.67998530210563 0.00234760070980945 0.0439827313150667 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 20/3682 54/18639 0.37037037037037 1.87488683686402 0.00236325123483941 0.0439827313150667 GO:0004713 protein tyrosine kinase activity 42/3682 140/18639 0.3 1.51865833785986 0.00240679042758927 0.0441794407256112 GO:0043130 ubiquitin binding 32/3682 100/18639 0.32 1.61990222705052 0.00249506677887295 0.0449864477094227 GO:0032182 ubiquitin-like protein binding 37/3682 120/18639 0.308333333333333 1.5608432916893 0.00251789819269157 0.0449864477094227 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 21/3682 58/18639 0.362068965517241 1.83286351121017 0.00256870146244942 0.0452902626273976 GO:0003714 transcription corepressor activity 57/3682 204/18639 0.279411764705882 1.41443668722242 0.00288974428686248 0.0501832593116558 GO:0051219 phosphoprotein binding 30/3682 93/18639 0.32258064516129 1.63296595468802 0.00292111509426056 0.0501832593116558 GO:0004674 protein serine/threonine kinase activity 109/3682 433/18639 0.251732101616628 1.27431685009026 0.00313300126612442 0.0531420467924901 GO:0070063 RNA polymerase binding 21/3682 59/18639 0.355932203389831 1.80179802796932 0.00325752212183387 0.0545634955407173 GO:0050431 transforming growth factor beta binding 11/3682 24/18639 0.458333333333333 2.32017246061923 0.00340320327239234 0.0562999059877252 GO:0008603 cAMP-dependent protein kinase regulator activity 7/3682 12/18639 0.583333333333333 2.95294676806084 0.00361441462095532 0.0590648242936601 GO:0004129 cytochrome-c oxidase activity 8/3682 15/18639 0.533333333333333 2.69983704508419 0.003896270213977 0.0621547867467759 GO:0120283 protein serine/threonine kinase binding 8/3682 15/18639 0.533333333333333 2.69983704508419 0.003896270213977 0.0621547867467759 GO:0046332 SMAD binding 26/3682 79/18639 0.329113924050633 1.66603868288423 0.00397095223706829 0.062600894090253 GO:0045499 chemorepellent activity 12/3682 28/18639 0.428571428571429 2.16951191122837 0.0044350220571387 0.068051444827358 GO:0046875 ephrin receptor binding 12/3682 28/18639 0.428571428571429 2.16951191122837 0.0044350220571387 0.068051444827358 GO:0005319 lipid transporter activity 50/3682 178/18639 0.280898876404494 1.42196473582384 0.0044823247426353 0.068051444827358 GO:0043175 RNA polymerase core enzyme binding 16/3682 42/18639 0.380952380952381 1.928455032203 0.00452931987922165 0.068051444827358 GO:0140296 general transcription initiation factor binding 19/3682 53/18639 0.358490566037736 1.81474895719103 0.00457061942870315 0.068051444827358 GO:0098631 cell adhesion mediator activity 25/3682 76/18639 0.328947368421053 1.66519554589897 0.00471286717511338 0.0693982638972739 GO:0022804 active transmembrane transporter activity 113/3682 457/18639 0.2472647702407 1.25170234995014 0.00489937959261786 0.0713605288489993 GO:0061659 ubiquitin-like protein ligase activity 94/3682 372/18639 0.252688172043011 1.27915666450562 0.00513911024355537 0.0740473949071419 GO:0120015 sterol transfer activity 13/3682 32/18639 0.40625 2.05651649918523 0.00538869032869685 0.0768175004303594 GO:0019208 phosphatase regulator activity 35/3682 117/18639 0.299145299145299 1.51433167592863 0.00553638853254083 0.078092217195839 GO:0005096 GTPase activator activity 71/3682 271/18639 0.261992619926199 1.32625758902891 0.00566490866219062 0.079071339771899 GO:0008375 acetylglucosaminyltransferase activity 16/3682 43/18639 0.372093023255814 1.88360724075641 0.00591240847858862 0.079071339771899 GO:0004862 cAMP-dependent protein kinase inhibitor activity 6/3682 10/18639 0.6 3.03731667571972 0.0059598547141506 0.079071339771899 GO:0005528 FK506 binding 6/3682 10/18639 0.6 3.03731667571972 0.0059598547141506 0.079071339771899 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 6/3682 10/18639 0.6 3.03731667571972 0.0059598547141506 0.079071339771899 GO:0098505 G-rich strand telomeric DNA binding 6/3682 10/18639 0.6 3.03731667571972 0.0059598547141506 0.079071339771899 GO:0000993 RNA polymerase II complex binding 14/3682 36/18639 0.388888888888889 1.96863117870722 0.00624089612964142 0.081192240909898 GO:0016409 palmitoyltransferase activity 14/3682 36/18639 0.388888888888889 1.96863117870722 0.00624089612964142 0.081192240909898 GO:0016675 oxidoreductase activity, acting on a heme group of donors 8/3682 16/18639 0.5 2.53109722976643 0.0064542189657386 0.0831601289816319 GO:0061630 ubiquitin protein ligase activity 89/3682 353/18639 0.252124645892351 1.27630398554795 0.00674433210739897 0.0860705240372821 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 11/3682 26/18639 0.423076923076923 2.14169765595621 0.00714783761333446 0.0903594566213979 GO:0050840 extracellular matrix binding 22/3682 67/18639 0.328358208955224 1.66221310611527 0.00790851482061158 0.0990412136413039 GO:0019003 GDP binding 24/3682 75/18639 0.32 1.61990222705052 0.00812002966536154 0.100748516218375 GO:0019213 deacetylase activity 14/3682 37/18639 0.378378378378378 1.91542493063406 0.00824606924312815 0.101373695282493 GO:0031624 ubiquitin conjugating enzyme binding 12/3682 30/18639 0.4 2.02487778381315 0.00853916329877625 0.10308539477802 GO:0051721 protein phosphatase 2A binding 12/3682 30/18639 0.4 2.02487778381315 0.00853916329877625 0.10308539477802 GO:0035591 signaling adaptor activity 37/3682 129/18639 0.286821705426357 1.45194724808307 0.00926540285587122 0.110853927025602 GO:0017110 nucleoside diphosphate phosphatase activity 8/3682 17/18639 0.470588235294118 2.38220915742723 0.0101045463043423 0.117739930850597 GO:0038191 neuropilin binding 8/3682 17/18639 0.470588235294118 2.38220915742723 0.0101045463043423 0.117739930850597 GO:0051787 misfolded protein binding 8/3682 17/18639 0.470588235294118 2.38220915742723 0.0101045463043423 0.117739930850597 GO:0019902 phosphatase binding 51/3682 190/18639 0.268421052631579 1.35879956545356 0.0106216762207163 0.120092210594606 GO:0042162 telomeric DNA binding 14/3682 38/18639 0.368421052631579 1.86501901140684 0.0107278239945035 0.120092210594606 GO:0019992 diacylglycerol binding 7/3682 14/18639 0.5 2.53109722976643 0.010809901060643 0.120092210594606 GO:0071933 Arp2/3 complex binding 7/3682 14/18639 0.5 2.53109722976643 0.010809901060643 0.120092210594606 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 6/3682 11/18639 0.545454545454545 2.76119697792702 0.0109337684272701 0.120092210594606 GO:0034713 type I transforming growth factor beta receptor binding 6/3682 11/18639 0.545454545454545 2.76119697792702 0.0109337684272701 0.120092210594606 GO:0048185 activin binding 6/3682 11/18639 0.545454545454545 2.76119697792702 0.0109337684272701 0.120092210594606 GO:0120013 lipid transfer activity 21/3682 65/18639 0.323076923076923 1.63547821000293 0.0113719918481791 0.123523639594164 GO:0001618 virus receptor activity 25/3682 81/18639 0.308641975308642 1.56240569738669 0.0114546965514761 0.123523639594164 GO:0030215 semaphorin receptor binding 10/3682 24/18639 0.416666666666667 2.10924769147203 0.0115227275740825 0.123523639594164 GO:0005178 integrin binding 44/3682 161/18639 0.273291925465839 1.38345687092824 0.0121534305965276 0.129250769836087 GO:0106310 protein serine kinase activity 89/3682 361/18639 0.246537396121884 1.24802024071586 0.0123745090008288 0.130565685520556 GO:0061631 ubiquitin conjugating enzyme activity 13/3682 35/18639 0.371428571428571 1.88024365639792 0.0127363945616578 0.133334130567355 GO:0017124 SH3 domain binding 33/3682 115/18639 0.28695652173913 1.45262971447465 0.0133312575582462 0.1371223679968 GO:0140272 exogenous protein binding 25/3682 82/18639 0.304878048780488 1.54335196936978 0.0134590278065976 0.1371223679968 GO:0036408 histone H3K14 acetyltransferase activity 11/3682 28/18639 0.392857142857143 1.98871925195934 0.0135075765489385 0.1371223679968 GO:0051537 2 iron, 2 sulfur cluster binding 11/3682 28/18639 0.392857142857143 1.98871925195934 0.0135075765489385 0.1371223679968 GO:0019888 protein phosphatase regulator activity 31/3682 107/18639 0.289719626168224 1.46661708640672 0.0140046171561622 0.140422720423311 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 68/3682 268/18639 0.253731343283582 1.28443740017998 0.0140422720423311 0.140422720423311 GO:0004706 JUN kinase kinase kinase activity 8/3682 18/18639 0.444444444444444 2.24986420423683 0.0150857866758202 0.147554409821891 GO:0070628 proteasome binding 8/3682 18/18639 0.444444444444444 2.24986420423683 0.0150857866758202 0.147554409821891 GO:0098641 cadherin binding involved in cell-cell adhesion 8/3682 18/18639 0.444444444444444 2.24986420423683 0.0150857866758202 0.147554409821891 GO:0001217 DNA-binding transcription repressor activity 70/3682 278/18639 0.251798561151079 1.27465328117734 0.0152882713585124 0.148451330582656 GO:0017025 TBP-class protein binding 10/3682 25/18639 0.4 2.02487778381315 0.0158679707163568 0.149227570481255 GO:0019706 protein-cysteine S-palmitoyltransferase activity 10/3682 25/18639 0.4 2.02487778381315 0.0158679707163568 0.149227570481255 GO:0019707 protein-cysteine S-acyltransferase activity 10/3682 25/18639 0.4 2.02487778381315 0.0158679707163568 0.149227570481255 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 10/3682 25/18639 0.4 2.02487778381315 0.0158679707163568 0.149227570481255 GO:0140313 molecular sequestering activity 18/3682 55/18639 0.327272727272727 1.65671818675621 0.0159482085109791 0.149227570481255 GO:0004879 nuclear receptor activity 19/3682 59/18639 0.322033898305085 1.63019821578177 0.0161477594923746 0.149227570481255 GO:0031593 polyubiquitin modification-dependent protein binding 19/3682 59/18639 0.322033898305085 1.63019821578177 0.0161477594923746 0.149227570481255 GO:0044390 ubiquitin-like protein conjugating enzyme binding 13/3682 36/18639 0.361111111111111 1.82801466594242 0.0164077632406235 0.150591799605723 GO:0000774 adenyl-nucleotide exchange factor activity 7/3682 15/18639 0.466666666666667 2.36235741444867 0.0168593280514758 0.150609997259851 GO:0050700 CARD domain binding 7/3682 15/18639 0.466666666666667 2.36235741444867 0.0168593280514758 0.150609997259851 GO:0141050 histone H3K deacetylase activity 7/3682 15/18639 0.466666666666667 2.36235741444867 0.0168593280514758 0.150609997259851 GO:0141051 histone H4K deacetylase activity 7/3682 15/18639 0.466666666666667 2.36235741444867 0.0168593280514758 0.150609997259851 GO:0004532 RNA exonuclease activity 14/3682 40/18639 0.35 1.7717680608365 0.0174030035026975 0.154437249626587 GO:0043178 alcohol binding 27/3682 92/18639 0.293478260869565 1.48564402616725 0.0176068343989925 0.154804960715214 GO:0010484 histone H3 acetyltransferase activity 11/3682 29/18639 0.379310344827586 1.92014272602971 0.017958300449327 0.154804960715214 GO:0001223 transcription coactivator binding 15/3682 44/18639 0.340909090909091 1.72574811120438 0.018151268325344 0.154804960715214 GO:0005527 macrolide binding 6/3682 12/18639 0.5 2.53109722976643 0.0182531222335849 0.154804960715214 GO:0043047 single-stranded telomeric DNA binding 6/3682 12/18639 0.5 2.53109722976643 0.0182531222335849 0.154804960715214 GO:0070410 co-SMAD binding 6/3682 12/18639 0.5 2.53109722976643 0.0182531222335849 0.154804960715214 GO:0141221 histone deacetylase activity, hydrolytic mechanism 6/3682 12/18639 0.5 2.53109722976643 0.0182531222335849 0.154804960715214 GO:0070034 telomerase RNA binding 9/3682 22/18639 0.409090909090909 2.07089773344526 0.018576816006914 0.156559329869589 GO:0005080 protein kinase C binding 17/3682 52/18639 0.326923076923077 1.65494818869344 0.0190540946129365 0.158218995055761 GO:0005518 collagen binding 22/3682 72/18639 0.305555555555556 1.54678164041282 0.0190990079051421 0.158218995055761 GO:0005548 phospholipid transporter activity 21/3682 68/18639 0.308823529411765 1.56332475956162 0.0192622845492149 0.158218995055761 GO:0140223 general transcription initiation factor activity 21/3682 68/18639 0.308823529411765 1.56332475956162 0.0192622845492149 0.158218995055761 GO:0098531 ligand-modulated transcription factor activity 19/3682 60/18639 0.316666666666667 1.60302824551874 0.0193641158127947 0.158218995055761 GO:0140311 protein sequestering activity 12/3682 33/18639 0.363636363636364 1.84079798528468 0.0195892564106794 0.159088506607942 GO:0019903 protein phosphatase binding 39/3682 144/18639 0.270833333333333 1.37101099945682 0.0201001417956016 0.16225415666329 GO:0019838 growth factor binding 37/3682 136/18639 0.272058823529412 1.37721466913762 0.0215677189680682 0.173058343815637 GO:0140303 intramembrane lipid transporter activity 15/3682 45/18639 0.333333333333333 1.68739815317762 0.0223794207057084 0.178502522295531 GO:0160215 deacylase activity 20/3682 65/18639 0.307692307692308 1.55759829524088 0.0229038179893591 0.181337514766957 GO:0034212 protein N-acetyltransferase activity 17/3682 53/18639 0.320754716981132 1.62372275117092 0.0230231477909017 0.181337514766957 GO:0043995 histone H4K5 acetyltransferase activity 11/3682 30/18639 0.366666666666667 1.85613796849538 0.0234114851154354 0.181337514766957 GO:0043996 histone H4K8 acetyltransferase activity 11/3682 30/18639 0.366666666666667 1.85613796849538 0.0234114851154354 0.181337514766957 GO:0043997 histone H4K12 acetyltransferase activity 11/3682 30/18639 0.366666666666667 1.85613796849538 0.0234114851154354 0.181337514766957 GO:0004707 MAP kinase activity 7/3682 16/18639 0.4375 2.21471007604563 0.0249521906737159 0.19106248858731 GO:0005159 insulin-like growth factor receptor binding 7/3682 16/18639 0.4375 2.21471007604563 0.0249521906737159 0.19106248858731 GO:0003925 G protein activity 17/3682 54/18639 0.314814814814815 1.59365381133442 0.0275874360096222 0.206758222691594 GO:0015485 cholesterol binding 17/3682 54/18639 0.314814814814815 1.59365381133442 0.0275874360096222 0.206758222691594 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 17/3682 54/18639 0.314814814814815 1.59365381133442 0.0275874360096222 0.206758222691594 GO:0004540 RNA nuclease activity 33/3682 121/18639 0.272727272727273 1.38059848896351 0.0277734926003634 0.206758222691594 GO:0051082 unfolded protein binding 33/3682 121/18639 0.272727272727273 1.38059848896351 0.0277734926003634 0.206758222691594 GO:0005338 nucleotide-sugar transmembrane transporter activity 6/3682 13/18639 0.461538461538462 2.33639744286132 0.0283243698472528 0.209445448457764 GO:0005525 GTP binding 90/3682 378/18639 0.238095238095238 1.20528439512687 0.0284470683726216 0.209445448457764 GO:1990782 protein tyrosine kinase binding 32/3682 117/18639 0.273504273504274 1.38453181799189 0.0287678157834226 0.210649580053477 GO:0003725 double-stranded RNA binding 22/3682 75/18639 0.293333333333333 1.48491037479631 0.0301981146725436 0.217467235267585 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:0031419 cobalamin binding 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:0099122 RNA polymerase II C-terminal domain binding 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 5/3682 10/18639 0.5 2.53109722976643 0.0311594844562509 0.217467235267585 GO:0004197 cysteine-type endopeptidase activity 25/3682 88/18639 0.284090909090909 1.43812342600365 0.0320155853746755 0.222284375140234 GO:0004712 protein serine/threonine/tyrosine kinase activity 14/3682 43/18639 0.325581395348837 1.64815633566186 0.0327658390933268 0.224749483383986 GO:0098632 cell-cell adhesion mediator activity 17/3682 55/18639 0.309090909090909 1.56467828749198 0.0327944588379626 0.224749483383986 GO:0004527 exonuclease activity 24/3682 84/18639 0.285714285714286 1.44634127415225 0.0329579226014258 0.224749483383986 GO:0042625 ATPase-coupled ion transmembrane transporter activity 9/3682 24/18639 0.375 1.89832292232482 0.0335446990125353 0.224749483383986 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 9/3682 24/18639 0.375 1.89832292232482 0.0335446990125353 0.224749483383986 GO:0046961 proton-transporting ATPase activity, rotational mechanism 9/3682 24/18639 0.375 1.89832292232482 0.0335446990125353 0.224749483383986 GO:0050699 WW domain binding 9/3682 24/18639 0.375 1.89832292232482 0.0335446990125353 0.224749483383986 GO:0002020 protease binding 36/3682 136/18639 0.264705882352941 1.33999265105282 0.0342921602460798 0.228614401640532 GO:0017022 myosin binding 22/3682 76/18639 0.289473684210526 1.46537208039109 0.0348099411544234 0.230917431420432 GO:0004659 prenyltransferase activity 7/3682 17/18639 0.411764705882353 2.08443301274883 0.0353455417322774 0.23217169569241 GO:0005092 GDP-dissociation inhibitor activity 7/3682 17/18639 0.411764705882353 2.08443301274883 0.0353455417322774 0.23217169569241 GO:0003924 GTPase activity 79/3682 331/18639 0.238670694864048 1.20819746919364 0.0360748146240844 0.235806105347674 GO:0032934 sterol binding 20/3682 68/18639 0.294117647058824 1.48888072339202 0.036552601077698 0.237769346816094 GO:0035401 histone H3Y41 kinase activity 31/3682 115/18639 0.269565217391304 1.36459154996103 0.037336097289202 0.240530626766974 GO:0140801 histone H2AXY142 kinase activity 31/3682 115/18639 0.269565217391304 1.36459154996103 0.037336097289202 0.240530626766974 GO:0042626 ATPase-coupled transmembrane transporter activity 27/3682 98/18639 0.275510204081633 1.39468622864681 0.0385120339310735 0.246919260610711 GO:0005484 SNAP receptor activity 12/3682 36/18639 0.333333333333333 1.68739815317762 0.0388171174034334 0.247690177717146 GO:0015036 disulfide oxidoreductase activity 13/3682 40/18639 0.325 1.64521319934818 0.0393890392254955 0.247874778685218 GO:0001046 core promoter sequence-specific DNA binding 14/3682 44/18639 0.318181818181818 1.61069823712409 0.0395859721183856 0.247874778685218 GO:0016790 thiolester hydrolase activity 14/3682 44/18639 0.318181818181818 1.61069823712409 0.0395859721183856 0.247874778685218 GO:0019205 nucleobase-containing compound kinase activity 14/3682 44/18639 0.318181818181818 1.61069823712409 0.0395859721183856 0.247874778685218 GO:0004705 JUN kinase activity 6/3682 14/18639 0.428571428571429 2.16951191122837 0.0414602214372102 0.25602164389798 GO:0046030 inositol trisphosphate phosphatase activity 6/3682 14/18639 0.428571428571429 2.16951191122837 0.0414602214372102 0.25602164389798 GO:1990825 sequence-specific mRNA binding 6/3682 14/18639 0.428571428571429 2.16951191122837 0.0414602214372102 0.25602164389798 GO:0019211 phosphatase activator activity 9/3682 25/18639 0.36 1.82239000543183 0.0434878586791356 0.266090094201104 GO:0120020 cholesterol transfer activity 9/3682 25/18639 0.36 1.82239000543183 0.0434878586791356 0.266090094201104 GO:0003697 single-stranded DNA binding 32/3682 121/18639 0.264462809917355 1.33876217111613 0.0444438066968601 0.270703186244511 GO:0019001 guanyl nucleotide binding 93/3682 400/18639 0.2325 1.17696021184139 0.0454982511646037 0.271592737801121 GO:0032561 guanyl ribonucleotide binding 93/3682 400/18639 0.2325 1.17696021184139 0.0454982511646037 0.271592737801121 GO:0016417 S-acyltransferase activity 10/3682 29/18639 0.344827586206897 1.74558429639064 0.0455954917990755 0.271592737801121 GO:0043236 laminin binding 10/3682 29/18639 0.344827586206897 1.74558429639064 0.0455954917990755 0.271592737801121 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 56/3682 229/18639 0.244541484716157 1.23791654905607 0.0459182218734418 0.271592737801121 GO:0071889 14-3-3 protein binding 11/3682 33/18639 0.333333333333333 1.68739815317762 0.0468428305466039 0.271592737801121 GO:0060590 ATPase regulator activity 15/3682 49/18639 0.306122448979592 1.54965136516312 0.046861001892738 0.271592737801121 GO:0046915 transition metal ion transmembrane transporter activity 14/3682 45/18639 0.311111111111111 1.57490494296578 0.0473566727563689 0.271592737801121 GO:0061650 ubiquitin-like protein conjugating enzyme activity 13/3682 41/18639 0.317073170731707 1.60508604814457 0.0475831619383869 0.271592737801121 GO:0004143 ATP-dependent diacylglycerol kinase activity 5/3682 11/18639 0.454545454545455 2.30099748160585 0.048014247813735 0.271592737801121 GO:0005225 volume-sensitive anion channel activity 5/3682 11/18639 0.454545454545455 2.30099748160585 0.048014247813735 0.271592737801121 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 5/3682 11/18639 0.454545454545455 2.30099748160585 0.048014247813735 0.271592737801121 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 5/3682 11/18639 0.454545454545455 2.30099748160585 0.048014247813735 0.271592737801121 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 5/3682 11/18639 0.454545454545455 2.30099748160585 0.048014247813735 0.271592737801121 GO:1900750 oligopeptide binding 5/3682 11/18639 0.454545454545455 2.30099748160585 0.048014247813735 0.271592737801121 GO:0008308 voltage-gated monoatomic anion channel activity 7/3682 18/18639 0.388888888888889 1.96863117870722 0.0482381131318409 0.271592737801121 GO:0017128 phospholipid scramblase activity 7/3682 18/18639 0.388888888888889 1.96863117870722 0.0482381131318409 0.271592737801121 GO:1990381 ubiquitin-specific protease binding 7/3682 18/18639 0.388888888888889 1.96863117870722 0.0482381131318409 0.271592737801121 GO:0001540 amyloid-beta binding 23/3682 83/18639 0.27710843373494 1.40277677794284 0.050003564632615 0.280354713839766 GO:0035173 histone kinase activity 84/3682 360/18639 0.233333333333333 1.18117870722433 0.0510208459168607 0.284866389702472 GO:0008093 cytoskeletal anchor activity 8/3682 22/18639 0.363636363636364 1.84079798528468 0.0525761184196858 0.291860271478385 GO:0008408 3'-5' exonuclease activity 17/3682 58/18639 0.293103448275862 1.48374665193205 0.0527090938043054 0.291860271478385 GO:0017069 snRNA binding 16/3682 54/18639 0.296296296296296 1.49990946949122 0.0539847407735898 0.297693632249425 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 110/3682 484/18639 0.227272727272727 1.15049874080292 0.0558497918541019 0.30524997959495 GO:0004860 protein kinase inhibitor activity 23/3682 84/18639 0.273809523809524 1.3860770543959 0.0564306099886372 0.30524997959495 GO:0015035 protein-disulfide reductase activity 11/3682 34/18639 0.323529411764706 1.63776879573122 0.0573054522976995 0.30524997959495 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 12/3682 38/18639 0.315789473684211 1.59858772406301 0.05731484723409 0.30524997959495 GO:0016922 nuclear receptor binding 35/3682 137/18639 0.255474452554745 1.29326135827482 0.0578587624004802 0.30524997959495 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 6/3682 15/18639 0.4 2.02487778381315 0.0578608170276995 0.30524997959495 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 6/3682 15/18639 0.4 2.02487778381315 0.0578608170276995 0.30524997959495 GO:0005041 low-density lipoprotein particle receptor activity 6/3682 15/18639 0.4 2.02487778381315 0.0578608170276995 0.30524997959495 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 6/3682 15/18639 0.4 2.02487778381315 0.0578608170276995 0.30524997959495 GO:0031005 filamin binding 6/3682 15/18639 0.4 2.02487778381315 0.0578608170276995 0.30524997959495 GO:0061578 K63-linked deubiquitinase activity 6/3682 15/18639 0.4 2.02487778381315 0.0578608170276995 0.30524997959495 GO:0051536 iron-sulfur cluster binding 21/3682 76/18639 0.276315789473684 1.39876425855513 0.0607516054017405 0.319243730346401 GO:0141003 histone H2AX kinase activity 82/3682 354/18639 0.231638418079096 1.17259871661496 0.0614895873384799 0.321859558724856 GO:0001216 DNA-binding transcription activator activity 111/3682 491/18639 0.226069246435845 1.14440648677831 0.062109346533858 0.323838616168754 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 7/3682 19/18639 0.368421052631579 1.86501901140684 0.0637602955176859 0.325672495363043 GO:0005520 insulin-like growth factor binding 7/3682 19/18639 0.368421052631579 1.86501901140684 0.0637602955176859 0.325672495363043 GO:0008301 DNA binding, bending 7/3682 19/18639 0.368421052631579 1.86501901140684 0.0637602955176859 0.325672495363043 GO:0050145 nucleoside monophosphate kinase activity 7/3682 19/18639 0.368421052631579 1.86501901140684 0.0637602955176859 0.325672495363043 GO:1990380 K48-linked deubiquitinase activity 7/3682 19/18639 0.368421052631579 1.86501901140684 0.0637602955176859 0.325672495363043 GO:0016758 hexosyltransferase activity 48/3682 197/18639 0.243654822335025 1.23342809166283 0.0639193031943883 0.325672495363043 GO:0042171 lysophosphatidic acid acyltransferase activity 8/3682 23/18639 0.347826086956522 1.7607632902723 0.0671306030578566 0.335756957316544 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 8/3682 23/18639 0.347826086956522 1.7607632902723 0.0671306030578566 0.335756957316544 GO:0071617 lysophospholipid acyltransferase activity 8/3682 23/18639 0.347826086956522 1.7607632902723 0.0671306030578566 0.335756957316544 GO:0016757 glycosyltransferase activity 63/3682 267/18639 0.235955056179775 1.19445037809202 0.0677074146218643 0.335756957316544 GO:0019210 kinase inhibitor activity 24/3682 90/18639 0.266666666666667 1.3499185225421 0.068151226607123 0.335756957316544 GO:0016776 phosphotransferase activity, phosphate group as acceptor 12/3682 39/18639 0.307692307692308 1.55759829524088 0.0684576337312029 0.335756957316544 GO:0051540 metal cluster binding 21/3682 77/18639 0.272727272727273 1.38059848896351 0.0685611461672452 0.335756957316544 GO:0000175 3'-5'-RNA exonuclease activity 11/3682 35/18639 0.314285714285714 1.59097540156747 0.0692029237880008 0.335756957316544 GO:0005154 epidermal growth factor receptor binding 11/3682 35/18639 0.314285714285714 1.59097540156747 0.0692029237880008 0.335756957316544 GO:0010485 histone H4 acetyltransferase activity 11/3682 35/18639 0.314285714285714 1.59097540156747 0.0692029237880008 0.335756957316544 GO:0005095 GTPase inhibitor activity 5/3682 12/18639 0.416666666666667 2.10924769147203 0.0692721946566993 0.335756957316544 GO:0005247 voltage-gated chloride channel activity 5/3682 12/18639 0.416666666666667 2.10924769147203 0.0692721946566993 0.335756957316544 GO:0035259 nuclear glucocorticoid receptor binding 5/3682 12/18639 0.416666666666667 2.10924769147203 0.0692721946566993 0.335756957316544 GO:0070325 lipoprotein particle receptor binding 10/3682 31/18639 0.32258064516129 1.63296595468802 0.0694064755049871 0.335756957316544 GO:0005496 steroid binding 28/3682 108/18639 0.259259259259259 1.31242078580482 0.0708691893443297 0.341026926048679 GO:0004521 RNA endonuclease activity 20/3682 73/18639 0.273972602739726 1.38690259165284 0.0712593576818134 0.341026926048679 GO:0043539 protein serine/threonine kinase activator activity 20/3682 73/18639 0.273972602739726 1.38690259165284 0.0712593576818134 0.341026926048679 GO:0019955 cytokine binding 36/3682 144/18639 0.25 1.26554861488322 0.0720538649379508 0.343110923216122 GO:0140996 histone H3 kinase activity 82/3682 357/18639 0.2296918767507 1.1627449458871 0.0722069256320495 0.343110923216122 GO:0002039 p53 binding 19/3682 69/18639 0.27536231884058 1.3939376047989 0.0740390952595617 0.350573807942801 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 6/3682 16/18639 0.375 1.89832292232482 0.0776059928400899 0.362341569357911 GO:0017070 U6 snRNA binding 6/3682 16/18639 0.375 1.89832292232482 0.0776059928400899 0.362341569357911 GO:0034450 ubiquitin-ubiquitin ligase activity 6/3682 16/18639 0.375 1.89832292232482 0.0776059928400899 0.362341569357911 GO:0140328 floppase activity 6/3682 16/18639 0.375 1.89832292232482 0.0776059928400899 0.362341569357911 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 7/3682 20/18639 0.35 1.7717680608365 0.0819690094703116 0.375529586754009 GO:0052745 inositol phosphate phosphatase activity 7/3682 20/18639 0.35 1.7717680608365 0.0819690094703116 0.375529586754009 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 11/3682 36/18639 0.305555555555556 1.54678164041282 0.0825726785972104 0.375529586754009 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 11/3682 36/18639 0.305555555555556 1.54678164041282 0.0825726785972104 0.375529586754009 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 11/3682 36/18639 0.305555555555556 1.54678164041282 0.0825726785972104 0.375529586754009 GO:0097110 scaffold protein binding 19/3682 70/18639 0.271428571428571 1.37402421044463 0.0835555110431164 0.375529586754009 GO:0030515 snoRNA binding 10/3682 32/18639 0.3125 1.58193576860402 0.0837920071733317 0.375529586754009 GO:0001091 RNA polymerase II general transcription initiation factor binding 8/3682 24/18639 0.333333333333333 1.68739815317762 0.0839235550805174 0.375529586754009 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 8/3682 24/18639 0.333333333333333 1.68739815317762 0.0839235550805174 0.375529586754009 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 8/3682 24/18639 0.333333333333333 1.68739815317762 0.0839235550805174 0.375529586754009 GO:0030552 cAMP binding 8/3682 24/18639 0.333333333333333 1.68739815317762 0.0839235550805174 0.375529586754009 GO:0019789 SUMO transferase activity 9/3682 28/18639 0.321428571428571 1.62713393342128 0.0843540340395199 0.375529586754009 GO:0051019 mitogen-activated protein kinase binding 9/3682 28/18639 0.321428571428571 1.62713393342128 0.0843540340395199 0.375529586754009 GO:0097718 disordered domain specific binding 9/3682 28/18639 0.321428571428571 1.62713393342128 0.0843540340395199 0.375529586754009 GO:0051018 protein kinase A binding 15/3682 53/18639 0.283018867924528 1.43269654515081 0.085805798638926 0.380727715815102 GO:0016651 oxidoreductase activity, acting on NAD(P)H 23/3682 88/18639 0.261363636363636 1.32307355192336 0.0879366256602339 0.388894648134368 GO:0000287 magnesium ion binding 54/3682 230/18639 0.234782608695652 1.1885152209338 0.0913746299106796 0.40276975026418 GO:0004715 non-membrane spanning protein tyrosine kinase activity 13/3682 45/18639 0.288888888888889 1.46241173275394 0.0918114500927872 0.403368338112573 GO:0005035 death receptor activity 5/3682 13/18639 0.384615384615385 1.9469978690511 0.0948645851626037 0.412722545837302 GO:0019855 calcium channel inhibitor activity 5/3682 13/18639 0.384615384615385 1.9469978690511 0.0948645851626037 0.412722545837302 GO:0140333 glycerophospholipid flippase activity 5/3682 13/18639 0.384615384615385 1.9469978690511 0.0948645851626037 0.412722545837302 GO:0004549 tRNA-specific ribonuclease activity 6/3682 17/18639 0.352941176470588 1.78665686807042 0.100657147989806 0.431111994514154 GO:0008429 phosphatidylethanolamine binding 6/3682 17/18639 0.352941176470588 1.78665686807042 0.100657147989806 0.431111994514154 GO:0031489 myosin V binding 6/3682 17/18639 0.352941176470588 1.78665686807042 0.100657147989806 0.431111994514154 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 7/3682 21/18639 0.333333333333333 1.68739815317762 0.102847146343401 0.431111994514154 GO:0009931 calcium-dependent protein serine/threonine kinase activity 7/3682 21/18639 0.333333333333333 1.68739815317762 0.102847146343401 0.431111994514154 GO:0035613 RNA stem-loop binding 7/3682 21/18639 0.333333333333333 1.68739815317762 0.102847146343401 0.431111994514154 GO:0072542 protein phosphatase activator activity 7/3682 21/18639 0.333333333333333 1.68739815317762 0.102847146343401 0.431111994514154 GO:0140312 cargo adaptor activity 7/3682 21/18639 0.333333333333333 1.68739815317762 0.102847146343401 0.431111994514154 GO:1904047 S-adenosyl-L-methionine binding 7/3682 21/18639 0.333333333333333 1.68739815317762 0.102847146343401 0.431111994514154 GO:0003707 nuclear steroid receptor activity 8/3682 25/18639 0.32 1.61990222705052 0.102952118092932 0.431111994514154 GO:0015662 P-type ion transporter activity 8/3682 25/18639 0.32 1.61990222705052 0.102952118092932 0.431111994514154 GO:0140358 P-type transmembrane transporter activity 8/3682 25/18639 0.32 1.61990222705052 0.102952118092932 0.431111994514154 GO:0004518 nuclease activity 49/3682 209/18639 0.23444976076555 1.18683027998617 0.105374899863049 0.439882759552913 GO:0030291 protein serine/threonine kinase inhibitor activity 13/3682 46/18639 0.282608695652174 1.43062017334624 0.105868343930647 0.440570126916359 GO:0030971 receptor tyrosine kinase binding 21/3682 81/18639 0.259259259259259 1.31242078580482 0.10651881908893 0.44190469838751 GO:0016859 cis-trans isomerase activity 12/3682 42/18639 0.285714285714286 1.44634127415225 0.10983866522168 0.454271022830404 GO:0043531 ADP binding 11/3682 38/18639 0.289473684210526 1.46537208039109 0.113775476935206 0.454549015136834 GO:0140030 modification-dependent protein binding 41/3682 173/18639 0.236994219653179 1.19971082566964 0.113937837407952 0.454549015136834 GO:0042826 histone deacetylase binding 31/3682 127/18639 0.244094488188976 1.23565376571275 0.114719723381555 0.454549015136834 GO:0001094 TFIID-class transcription factor complex binding 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0003680 minor groove of adenine-thymine-rich DNA binding 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0004382 GDP phosphatase activity 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0004445 inositol-polyphosphate 5-phosphatase activity 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0008190 eukaryotic initiation factor 4E binding 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0019911 structural constituent of myelin sheath 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0033204 ribonuclease P RNA binding 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0043295 glutathione binding 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0043422 protein kinase B binding 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0140999 histone H3K4 trimethyltransferase activity 4/3682 10/18639 0.4 2.02487778381315 0.116528540080658 0.454549015136834 GO:0008376 acetylgalactosaminyltransferase activity 10/3682 34/18639 0.294117647058824 1.48888072339202 0.117586622525656 0.454549015136834 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 10/3682 34/18639 0.294117647058824 1.48888072339202 0.117586622525656 0.454549015136834 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 16/3682 60/18639 0.266666666666667 1.3499185225421 0.120020283942018 0.454549015136834 GO:0061733 protein-lysine-acetyltransferase activity 13/3682 47/18639 0.276595744680851 1.40018144625377 0.121133598481326 0.454549015136834 GO:0008080 N-acetyltransferase activity 18/3682 69/18639 0.260869565217391 1.32057246770422 0.122270492939859 0.454549015136834 GO:0019199 transmembrane receptor protein kinase activity 20/3682 78/18639 0.256410256410256 1.2979985793674 0.123371266355811 0.454549015136834 GO:0004112 cyclic-nucleotide phosphodiesterase activity 8/3682 26/18639 0.307692307692308 1.55759829524088 0.124164253179835 0.454549015136834 GO:0034237 protein kinase A regulatory subunit binding 8/3682 26/18639 0.307692307692308 1.55759829524088 0.124164253179835 0.454549015136834 GO:0070412 R-SMAD binding 8/3682 26/18639 0.307692307692308 1.55759829524088 0.124164253179835 0.454549015136834 GO:0008174 mRNA methyltransferase activity 5/3682 14/18639 0.357142857142857 1.80792659269031 0.124533676121156 0.454549015136834 GO:0034236 protein kinase A catalytic subunit binding 5/3682 14/18639 0.357142857142857 1.80792659269031 0.124533676121156 0.454549015136834 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 5/3682 14/18639 0.357142857142857 1.80792659269031 0.124533676121156 0.454549015136834 GO:0044548 S100 protein binding 5/3682 14/18639 0.357142857142857 1.80792659269031 0.124533676121156 0.454549015136834 GO:0008649 rRNA methyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0032931 histone H3K56 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0034062 5'-3' RNA polymerase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0043992 histone H3K9 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0043993 histone H3K18 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0043994 histone H3K23 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0043999 histone H2AK5 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0044012 histone H2AK9 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0044014 histone H2BK5 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0044015 histone H2BK12 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0044016 histone H3K4 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0044017 histone H3K27 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0044018 histone H3K36 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0061133 endopeptidase activator activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0097747 RNA polymerase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0140908 histone H3K122 acetyltransferase activity 7/3682 22/18639 0.318181818181818 1.61069823712409 0.126306959374468 0.454549015136834 GO:0000900 mRNA regulatory element binding translation repressor activity 6/3682 18/18639 0.333333333333333 1.68739815317762 0.126866665418788 0.454549015136834 GO:0030228 lipoprotein particle receptor activity 6/3682 18/18639 0.333333333333333 1.68739815317762 0.126866665418788 0.454549015136834 GO:0035615 clathrin adaptor activity 6/3682 18/18639 0.333333333333333 1.68739815317762 0.126866665418788 0.454549015136834 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 6/3682 18/18639 0.333333333333333 1.68739815317762 0.126866665418788 0.454549015136834 GO:0050811 GABA receptor binding 6/3682 18/18639 0.333333333333333 1.68739815317762 0.126866665418788 0.454549015136834 GO:0070064 proline-rich region binding 6/3682 18/18639 0.333333333333333 1.68739815317762 0.126866665418788 0.454549015136834 GO:0019887 protein kinase regulator activity 58/3682 255/18639 0.227450980392157 1.15140109275649 0.130279249641182 0.46553118538449 GO:0030159 signaling receptor complex adaptor activity 14/3682 52/18639 0.269230769230769 1.36289850833577 0.131439595897609 0.467681025334968 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 11/3682 39/18639 0.282051282051282 1.42779843730414 0.131578915336778 0.467681025334968 GO:0008013 beta-catenin binding 26/3682 106/18639 0.245283018867925 1.2416703391307 0.133226757695065 0.472285331511608 GO:0051087 protein-folding chaperone binding 32/3682 134/18639 0.238805970149254 1.20888225899292 0.137426313497505 0.485887229780097 GO:0016411 acylglycerol O-acyltransferase activity 9/3682 31/18639 0.290322580645161 1.46966935921922 0.142285858375816 0.501744869009457 GO:0005385 zinc ion transmembrane transporter activity 8/3682 27/18639 0.296296296296296 1.49990946949122 0.147461751073622 0.513461023288747 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 8/3682 27/18639 0.296296296296296 1.49990946949122 0.147461751073622 0.513461023288747 GO:0016251 RNA polymerase II general transcription initiation factor activity 14/3682 53/18639 0.264150943396226 1.33718344214076 0.147820959016111 0.513461023288747 GO:0003727 single-stranded RNA binding 22/3682 89/18639 0.247191011235955 1.25132896752498 0.148097449568778 0.513461023288747 GO:0004679 AMP-activated protein kinase activity 56/3682 248/18639 0.225806451612903 1.14307616828161 0.148201699627833 0.513461023288747 GO:0048306 calcium-dependent protein binding 20/3682 80/18639 0.25 1.26554861488322 0.149307643960839 0.513461023288747 GO:0061791 GTPase motor activity 11/3682 40/18639 0.275 1.39210347637154 0.150796033883285 0.513461023288747 GO:1990606 membrane scission GTPase motor activity 11/3682 40/18639 0.275 1.39210347637154 0.150796033883285 0.513461023288747 GO:0044013 histone H2B acetyltransferase activity 7/3682 23/18639 0.304347826086957 1.54066787898826 0.152196615262986 0.513461023288747 GO:0070577 lysine-acetylated histone binding 7/3682 23/18639 0.304347826086957 1.54066787898826 0.152196615262986 0.513461023288747 GO:0140102 catalytic activity, acting on a rRNA 7/3682 23/18639 0.304347826086957 1.54066787898826 0.152196615262986 0.513461023288747 GO:0019207 kinase regulator activity 64/3682 287/18639 0.222996515679443 1.12885172616761 0.154661160553713 0.513461023288747 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0000099 sulfur amino acid transmembrane transporter activity 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0015217 ADP transmembrane transporter activity 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0032050 clathrin heavy chain binding 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0034056 estrogen response element binding 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0045294 alpha-catenin binding 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0140537 transcription regulator activator activity 4/3682 11/18639 0.363636363636364 1.84079798528468 0.155679564233186 0.513461023288747 GO:0015245 fatty acid transmembrane transporter activity 6/3682 19/18639 0.315789473684211 1.59858772406301 0.15599268229622 0.513461023288747 GO:0042800 histone H3K4 methyltransferase activity 6/3682 19/18639 0.315789473684211 1.59858772406301 0.15599268229622 0.513461023288747 GO:0008173 RNA methyltransferase activity 17/3682 67/18639 0.253731343283582 1.28443740017998 0.157504674723523 0.513461023288747 GO:0004559 alpha-mannosidase activity 5/3682 15/18639 0.333333333333333 1.68739815317762 0.157870105667883 0.513461023288747 GO:0015929 hexosaminidase activity 5/3682 15/18639 0.333333333333333 1.68739815317762 0.157870105667883 0.513461023288747 GO:0016846 carbon-sulfur lyase activity 5/3682 15/18639 0.333333333333333 1.68739815317762 0.157870105667883 0.513461023288747 GO:0048531 beta-1,3-galactosyltransferase activity 5/3682 15/18639 0.333333333333333 1.68739815317762 0.157870105667883 0.513461023288747 GO:0050780 dopamine receptor binding 5/3682 15/18639 0.333333333333333 1.68739815317762 0.157870105667883 0.513461023288747 GO:0140776 protein-containing complex destabilizing activity 5/3682 15/18639 0.333333333333333 1.68739815317762 0.157870105667883 0.513461023288747 GO:0004519 endonuclease activity 30/3682 127/18639 0.236220472440945 1.19579396681879 0.161582109892726 0.524261567206422 GO:0140857 histone H3T45 kinase activity 55/3682 246/18639 0.223577235772358 1.1317914442045 0.170144025772903 0.550707716269781 GO:0005126 cytokine receptor binding 61/3682 275/18639 0.221818181818182 1.12288677102365 0.172521037030825 0.557055878605555 GO:0035402 histone H3T11 kinase activity 55/3682 247/18639 0.222672064777328 1.12720929260853 0.178566284840445 0.565662878777456 GO:0043998 histone H2A acetyltransferase activity 7/3682 24/18639 0.291666666666667 1.47647338403042 0.180309051808709 0.565662878777456 GO:0048027 mRNA 5'-UTR binding 7/3682 24/18639 0.291666666666667 1.47647338403042 0.180309051808709 0.565662878777456 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 7/3682 24/18639 0.291666666666667 1.47647338403042 0.180309051808709 0.565662878777456 GO:0140033 acetylation-dependent protein binding 7/3682 24/18639 0.291666666666667 1.47647338403042 0.180309051808709 0.565662878777456 GO:0016407 acetyltransferase activity 23/3682 96/18639 0.239583333333333 1.21281742259642 0.18041706881302 0.565662878777456 GO:0004180 carboxypeptidase activity 12/3682 46/18639 0.260869565217391 1.32057246770422 0.183205367870912 0.565662878777456 GO:0030276 clathrin binding 12/3682 46/18639 0.260869565217391 1.32057246770422 0.183205367870912 0.565662878777456 GO:0019209 kinase activator activity 34/3682 148/18639 0.22972972972973 1.16293656502782 0.187117208809507 0.565662878777456 GO:0061608 nuclear import signal receptor activity 6/3682 20/18639 0.3 1.51865833785986 0.187717113507323 0.565662878777456 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 38/3682 167/18639 0.227544910179641 1.15187658360628 0.188034464814307 0.565662878777456 GO:0000149 SNARE binding 25/3682 106/18639 0.235849056603774 1.19391378762568 0.19015603813162 0.565662878777456 GO:0004714 transmembrane receptor protein tyrosine kinase activity 15/3682 60/18639 0.25 1.26554861488322 0.192443174301404 0.565662878777456 GO:0004402 histone acetyltransferase activity 11/3682 42/18639 0.261904761904762 1.32581283463956 0.193192214139588 0.565662878777456 GO:0048487 beta-tubulin binding 11/3682 42/18639 0.261904761904762 1.32581283463956 0.193192214139588 0.565662878777456 GO:0030165 PDZ domain binding 20/3682 83/18639 0.240963855421687 1.21980589386334 0.193418255326679 0.565662878777456 GO:0004708 MAP kinase kinase activity 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0005024 transforming growth factor beta receptor activity 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0005324 long-chain fatty acid transmembrane transporter activity 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0005521 lamin binding 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0015562 efflux transmembrane transporter activity 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0015923 mannosidase activity 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0030275 LRR domain binding 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0031435 mitogen-activated protein kinase kinase kinase binding 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0043023 ribosomal large subunit binding 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0140327 flippase activity 5/3682 16/18639 0.3125 1.58193576860402 0.194353793316881 0.565662878777456 GO:0042277 peptide binding 55/3682 249/18639 0.220883534136546 1.11815540270806 0.196099576953015 0.565662878777456 GO:0000340 RNA 7-methylguanosine cap binding 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0004526 ribonuclease P activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0005025 transforming growth factor beta receptor activity, type I 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0005026 transforming growth factor beta receptor activity, type II 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016208 AMP binding 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016273 arginine N-methyltransferase activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016274 protein-arginine N-methyltransferase activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016361 activin receptor activity, type I 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016362 activin receptor activity, type II 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016423 tRNA (guanine) methyltransferase activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016801 hydrolase activity, acting on ether bonds 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0016803 ether hydrolase activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0017002 activin receptor activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0017166 vinculin binding 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0042301 phosphate ion binding 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0045295 gamma-catenin binding 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0070008 serine-type exopeptidase activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0097677 STAT family protein binding 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 4/3682 12/18639 0.333333333333333 1.68739815317762 0.198883249021429 0.565662878777456 GO:0004181 metallocarboxypeptidase activity 8/3682 29/18639 0.275862068965517 1.39646743711251 0.199717965445185 0.565662878777456 GO:0051861 glycolipid binding 8/3682 29/18639 0.275862068965517 1.39646743711251 0.199717965445185 0.565662878777456 GO:0038024 cargo receptor activity 16/3682 65/18639 0.246153846153846 1.2460786361927 0.200403483714443 0.565662878777456 GO:0004676 3-phosphoinositide-dependent protein kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0004711 ribosomal protein S6 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0035175 histone H3S10 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0035979 histone H2AXS139 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0044022 histone H3S28 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0044023 histone H4S1 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0044024 histone H2AS1 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0044025 histone H2BS14 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0072354 histone H3T3 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0072371 histone H2AS121 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0072518 Rho-dependent protein serine/threonine kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0140823 histone H2BS36 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0140855 histone H3S57 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0140995 histone H2A kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0140997 histone H4 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0140998 histone H2B kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:1990244 histone H2AT120 kinase activity 54/3682 245/18639 0.220408163265306 1.11574898291745 0.203469781769204 0.565662878777456 GO:0005109 frizzled binding 10/3682 38/18639 0.263157894736842 1.33215643671917 0.203961140798945 0.565854924783823 GO:0140938 histone H3 methyltransferase activity 12/3682 47/18639 0.25531914893617 1.29247518115733 0.204487117375913 0.566142019181246 GO:0008194 UDP-glycosyltransferase activity 33/3682 145/18639 0.227586206896552 1.15208563561782 0.207578940135183 0.573517071713702 GO:0031072 heat shock protein binding 30/3682 131/18639 0.229007633587786 1.15928117393882 0.210210561145518 0.577716571935341 GO:0000030 mannosyltransferase activity 7/3682 25/18639 0.28 1.4174144486692 0.210392303809288 0.577716571935341 GO:0008139 nuclear localization sequence binding 7/3682 25/18639 0.28 1.4174144486692 0.210392303809288 0.577716571935341 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 15/3682 61/18639 0.245901639344262 1.24480191627857 0.211398132933506 0.579291407220651 GO:0004677 DNA-dependent protein kinase activity 54/3682 246/18639 0.219512195121951 1.11121341794624 0.212842650643164 0.582059493595592 GO:0008175 tRNA methyltransferase activity 9/3682 34/18639 0.264705882352941 1.33999265105282 0.215618608914337 0.586423633003158 GO:0008200 ion channel inhibitor activity 11/3682 43/18639 0.255813953488372 1.29497997802003 0.216189010972806 0.586423633003158 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 11/3682 43/18639 0.255813953488372 1.29497997802003 0.216189010972806 0.586423633003158 GO:0048156 tau protein binding 11/3682 43/18639 0.255813953488372 1.29497997802003 0.216189010972806 0.586423633003158 GO:0005123 death receptor binding 6/3682 21/18639 0.285714285714286 1.44634127415225 0.221665100372892 0.599718561512286 GO:0033218 amide binding 54/3682 247/18639 0.218623481781377 1.10671457819747 0.222432929157915 0.599718561512286 GO:0035403 histone H3T6 kinase activity 54/3682 247/18639 0.218623481781377 1.10671457819747 0.222432929157915 0.599718561512286 GO:0016504 peptidase activator activity 14/3682 57/18639 0.245614035087719 1.24334600760456 0.22325062952519 0.600714545308744 GO:0001968 fibronectin binding 8/3682 30/18639 0.266666666666667 1.3499185225421 0.228296379110732 0.613060416850464 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 53/3682 243/18639 0.218106995884774 1.10410002615326 0.230625697171872 0.618076868420616 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 5/3682 17/18639 0.294117647058824 1.48888072339202 0.233394062203162 0.618782348688313 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 5/3682 17/18639 0.294117647058824 1.48888072339202 0.233394062203162 0.618782348688313 GO:0019198 transmembrane receptor protein phosphatase activity 5/3682 17/18639 0.294117647058824 1.48888072339202 0.233394062203162 0.618782348688313 GO:0032183 SUMO binding 5/3682 17/18639 0.294117647058824 1.48888072339202 0.233394062203162 0.618782348688313 GO:0048038 quinone binding 5/3682 17/18639 0.294117647058824 1.48888072339202 0.233394062203162 0.618782348688313 GO:0031490 chromatin DNA binding 29/3682 128/18639 0.2265625 1.14690343223791 0.233659603310662 0.618782348688313 GO:0016860 intramolecular oxidoreductase activity 13/3682 53/18639 0.245283018867925 1.2416703391307 0.23607382270578 0.623942647782534 GO:0042054 histone methyltransferase activity 16/3682 67/18639 0.238805970149254 1.20888225899292 0.23825063351561 0.624434309565218 GO:0016248 channel inhibitor activity 11/3682 44/18639 0.25 1.26554861488322 0.240239098785172 0.624434309565218 GO:0005112 Notch binding 7/3682 26/18639 0.269230769230769 1.36289850833577 0.242160532988561 0.624434309565218 GO:0050750 low-density lipoprotein particle receptor binding 7/3682 26/18639 0.269230769230769 1.36289850833577 0.242160532988561 0.624434309565218 GO:0097602 cullin family protein binding 7/3682 26/18639 0.269230769230769 1.36289850833577 0.242160532988561 0.624434309565218 GO:0004535 poly(A)-specific ribonuclease activity 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0005172 vascular endothelial growth factor receptor binding 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0009982 pseudouridine synthase activity 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0030955 potassium ion binding 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0031994 insulin-like growth factor I binding 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0035325 Toll-like receptor binding 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0046975 histone H3K36 methyltransferase activity 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0051011 microtubule minus-end binding 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0070123 transforming growth factor beta receptor activity, type III 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0070700 BMP receptor binding 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0140410 monoatomic cation:bicarbonate symporter activity 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 4/3682 13/18639 0.307692307692308 1.55759829524088 0.245113766292018 0.624434309565218 GO:0035254 glutamate receptor binding 12/3682 49/18639 0.244897959183673 1.2397210921305 0.250005774472001 0.635688307006607 GO:0030295 protein kinase activator activity 31/3682 139/18639 0.223021582733813 1.12897862047136 0.253817119250691 0.644157082946829 GO:0030331 nuclear estrogen receptor binding 10/3682 40/18639 0.25 1.26554861488322 0.254962027224702 0.644620974492642 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 10/3682 40/18639 0.25 1.26554861488322 0.254962027224702 0.644620974492642 GO:0046972 histone H4K16 acetyltransferase activity 6/3682 22/18639 0.272727272727273 1.38059848896351 0.257424403247301 0.649620904616542 GO:1990841 promoter-specific chromatin binding 16/3682 68/18639 0.235294117647059 1.19110457871361 0.258191309500216 0.650331493853928 GO:0051539 4 iron, 4 sulfur cluster binding 11/3682 45/18639 0.244444444444444 1.23742531233026 0.265218353902007 0.665529202675448 GO:0141110 transporter inhibitor activity 11/3682 45/18639 0.244444444444444 1.23742531233026 0.265218353902007 0.665529202675448 GO:0070888 E-box binding 14/3682 59/18639 0.23728813559322 1.20119868531288 0.266050735713562 0.666370067020885 GO:0005543 phospholipid binding 104/3682 497/18639 0.209255533199195 1.05929220078756 0.269448864883477 0.673622162208692 GO:0015605 organophosphate ester transmembrane transporter activity 12/3682 50/18639 0.24 1.21492667028789 0.274035024633816 0.676896959491334 GO:0032813 tumor necrosis factor receptor superfamily binding 12/3682 50/18639 0.24 1.21492667028789 0.274035024633816 0.676896959491334 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 5/3682 18/18639 0.277777777777778 1.40616512764802 0.274366137889459 0.676896959491334 GO:0008409 5'-3' exonuclease activity 5/3682 18/18639 0.277777777777778 1.40616512764802 0.274366137889459 0.676896959491334 GO:0031690 adrenergic receptor binding 5/3682 18/18639 0.277777777777778 1.40616512764802 0.274366137889459 0.676896959491334 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 5/3682 18/18639 0.277777777777778 1.40616512764802 0.274366137889459 0.676896959491334 GO:0015252 proton channel activity 7/3682 27/18639 0.259259259259259 1.31242078580482 0.275305106658789 0.676896959491334 GO:0023026 MHC class II protein complex binding 7/3682 27/18639 0.259259259259259 1.31242078580482 0.275305106658789 0.676896959491334 GO:0035255 ionotropic glutamate receptor binding 7/3682 27/18639 0.259259259259259 1.31242078580482 0.275305106658789 0.676896959491334 GO:0005200 structural constituent of cytoskeleton 25/3682 112/18639 0.223214285714286 1.12995412043144 0.280511438492935 0.688434665898413 GO:0001727 lipid kinase activity 10/3682 41/18639 0.24390243902439 1.23468157549582 0.28192993189192 0.689390709370753 GO:0017080 sodium channel regulator activity 10/3682 41/18639 0.24390243902439 1.23468157549582 0.28192993189192 0.689390709370753 GO:0016853 isomerase activity 39/3682 180/18639 0.216666666666667 1.09680879956545 0.285613166790945 0.6924829021019 GO:0008170 N-methyltransferase activity 22/3682 98/18639 0.224489795918367 1.13641100111962 0.286993532701072 0.6924829021019 GO:0008378 galactosyltransferase activity 8/3682 32/18639 0.25 1.26554861488322 0.28922585707592 0.6924829021019 GO:0051059 NF-kappaB binding 8/3682 32/18639 0.25 1.26554861488322 0.28922585707592 0.6924829021019 GO:0070717 poly-purine tract binding 8/3682 32/18639 0.25 1.26554861488322 0.28922585707592 0.6924829021019 GO:0140142 nucleocytoplasmic carrier activity 8/3682 32/18639 0.25 1.26554861488322 0.28922585707592 0.6924829021019 GO:0005161 platelet-derived growth factor receptor binding 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0005347 ATP transmembrane transporter activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0005545 1-phosphatidylinositol binding 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0008559 ABC-type xenobiotic transporter activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0015926 glucosidase activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0016530 metallochaperone activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0032036 myosin heavy chain binding 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0042813 Wnt receptor activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0061665 SUMO ligase activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0070742 C2H2 zinc finger domain binding 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0098821 BMP receptor activity 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:1901612 cardiolipin binding 4/3682 14/18639 0.285714285714286 1.44634127415225 0.293345802360364 0.6924829021019 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 6/3682 23/18639 0.260869565217391 1.32057246770422 0.294563622535883 0.6924829021019 GO:0008171 O-methyltransferase activity 6/3682 23/18639 0.260869565217391 1.32057246770422 0.294563622535883 0.6924829021019 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 6/3682 23/18639 0.260869565217391 1.32057246770422 0.294563622535883 0.6924829021019 GO:0005010 insulin-like growth factor receptor activity 12/3682 51/18639 0.235294117647059 1.19110457871361 0.298759626249889 0.698904899813701 GO:0005048 signal sequence binding 12/3682 51/18639 0.235294117647059 1.19110457871361 0.298759626249889 0.698904899813701 GO:0023023 MHC protein complex binding 9/3682 37/18639 0.243243243243243 1.23134459826475 0.30042479275574 0.698904899813701 GO:0030551 cyclic nucleotide binding 9/3682 37/18639 0.243243243243243 1.23134459826475 0.30042479275574 0.698904899813701 GO:0042805 actinin binding 9/3682 37/18639 0.243243243243243 1.23134459826475 0.30042479275574 0.698904899813701 GO:0043394 proteoglycan binding 9/3682 37/18639 0.243243243243243 1.23134459826475 0.30042479275574 0.698904899813701 GO:0016410 N-acyltransferase activity 21/3682 94/18639 0.223404255319149 1.13091578351266 0.301314684465442 0.699591256937373 GO:0051879 Hsp90 protein binding 10/3682 42/18639 0.238095238095238 1.20528439512687 0.309660468689524 0.699591256937373 GO:0043021 ribonucleoprotein complex binding 38/3682 177/18639 0.214689265536723 1.08679881052118 0.31026460351741 0.699591256937373 GO:0015026 coreceptor activity 14/3682 61/18639 0.229508196721311 1.16181512186 0.311405561632312 0.699591256937373 GO:0008234 cysteine-type peptidase activity 40/3682 187/18639 0.213903743315508 1.0828223442851 0.313313583709744 0.699591256937373 GO:0000182 rDNA binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0004090 carbonyl reductase (NADPH) activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0005031 tumor necrosis factor receptor activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0005345 purine nucleobase transmembrane transporter activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0005522 profilin binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0015203 polyamine transmembrane transporter activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0015279 store-operated calcium channel activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0015658 branched-chain amino acid transmembrane transporter activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0016427 tRNA (cytidine) methyltransferase activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0031996 thioesterase binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0035374 chondroitin sulfate binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0047429 nucleoside triphosphate diphosphatase activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0050815 phosphoserine residue binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0070097 delta-catenin binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0097177 mitochondrial ribosome binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0140135 mechanosensitive monoatomic cation channel activity 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:1905394 retromer complex binding 3/3682 10/18639 0.3 1.51865833785986 0.314773831990807 0.699591256937373 GO:0008235 metalloexopeptidase activity 15/3682 66/18639 0.227272727272727 1.15049874080292 0.31663260498392 0.699591256937373 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 5/3682 19/18639 0.263157894736842 1.33215643671917 0.316642372029902 0.699591256937373 GO:0008381 mechanosensitive monoatomic ion channel activity 5/3682 19/18639 0.263157894736842 1.33215643671917 0.316642372029902 0.699591256937373 GO:0031420 alkali metal ion binding 5/3682 19/18639 0.263157894736842 1.33215643671917 0.316642372029902 0.699591256937373 GO:0043395 heparan sulfate proteoglycan binding 5/3682 19/18639 0.263157894736842 1.33215643671917 0.316642372029902 0.699591256937373 GO:0046527 glucosyltransferase activity 5/3682 19/18639 0.263157894736842 1.33215643671917 0.316642372029902 0.699591256937373 GO:0043495 protein-membrane adaptor activity 11/3682 47/18639 0.234042553191489 1.18476891606088 0.317426480759644 0.699591256937373 GO:0140359 ABC-type transporter activity 11/3682 47/18639 0.234042553191489 1.18476891606088 0.317426480759644 0.699591256937373 GO:0070851 growth factor receptor binding 30/3682 139/18639 0.215827338129496 1.09255995529486 0.325082492495629 0.715288242929627 GO:0015101 organic cation transmembrane transporter activity 18/3682 81/18639 0.222222222222222 1.12493210211841 0.329251882252108 0.723274626586599 GO:0070300 phosphatidic acid binding 6/3682 24/18639 0.25 1.26554861488322 0.332648479444942 0.728347977869644 GO:0070840 dynein complex binding 6/3682 24/18639 0.25 1.26554861488322 0.332648479444942 0.728347977869644 GO:0015297 antiporter activity 29/3682 135/18639 0.214814814814815 1.08743436538113 0.338944284348941 0.740366998928607 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 15/3682 67/18639 0.223880597014925 1.13332711780586 0.339242789061317 0.740366998928607 GO:0004467 long-chain fatty acid-CoA ligase activity 4/3682 15/18639 0.266666666666667 1.3499185225421 0.34260969206672 0.744050165695088 GO:0042809 nuclear vitamin D receptor binding 4/3682 15/18639 0.266666666666667 1.3499185225421 0.34260969206672 0.744050165695088 GO:0051371 muscle alpha-actinin binding 4/3682 15/18639 0.266666666666667 1.3499185225421 0.34260969206672 0.744050165695088 GO:0008168 methyltransferase activity 43/3682 204/18639 0.21078431372549 1.06703118509761 0.343151494328033 0.744050165695088 GO:0003785 actin monomer binding 7/3682 29/18639 0.241379310344828 1.22190900747345 0.344437496959697 0.744429428912893 GO:0035250 UDP-galactosyltransferase activity 7/3682 29/18639 0.241379310344828 1.22190900747345 0.344437496959697 0.744429428912893 GO:0003735 structural constituent of ribosome 37/3682 175/18639 0.211428571428571 1.07029254287266 0.350370557427059 0.756033086879643 GO:0052866 phosphatidylinositol phosphate phosphatase activity 8/3682 34/18639 0.235294117647059 1.19110457871361 0.353534971156309 0.761634825320666 GO:0016741 transferase activity, transferring one-carbon groups 45/3682 215/18639 0.209302325581395 1.05952907292548 0.357847278633018 0.764974972174874 GO:0005507 copper ion binding 14/3682 63/18639 0.222222222222222 1.12493210211841 0.358587394827265 0.764974972174874 GO:1901682 sulfur compound transmembrane transporter activity 14/3682 63/18639 0.222222222222222 1.12493210211841 0.358587394827265 0.764974972174874 GO:0001972 retinoic acid binding 5/3682 20/18639 0.25 1.26554861488322 0.359617458204094 0.764974972174874 GO:0016004 phospholipase activator activity 5/3682 20/18639 0.25 1.26554861488322 0.359617458204094 0.764974972174874 GO:0016505 peptidase activator activity involved in apoptotic process 5/3682 20/18639 0.25 1.26554861488322 0.359617458204094 0.764974972174874 GO:0140939 histone H4 methyltransferase activity 5/3682 20/18639 0.25 1.26554861488322 0.359617458204094 0.764974972174874 GO:0008238 exopeptidase activity 22/3682 102/18639 0.215686274509804 1.09184586382081 0.359935254629192 0.764974972174874 GO:0000217 DNA secondary structure binding 9/3682 39/18639 0.230769230769231 1.16819872143066 0.360794165980985 0.764974972174874 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 9/3682 39/18639 0.230769230769231 1.16819872143066 0.360794165980985 0.764974972174874 GO:0030145 manganese ion binding 15/3682 68/18639 0.220588235294118 1.11666054254401 0.362181887050307 0.766704152681535 GO:0043022 ribosome binding 24/3682 112/18639 0.214285714285714 1.08475595561418 0.363798279369126 0.768364172152965 GO:0019783 ubiquitin-like protein peptidase activity 27/3682 127/18639 0.21259842519685 1.07621457013691 0.36857573452383 0.768364172152965 GO:0047617 fatty acyl-CoA hydrolase activity 6/3682 25/18639 0.24 1.21492667028789 0.371255692803569 0.768364172152965 GO:0002162 dystroglycan binding 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0003953 NAD+ nucleosidase activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0010854 adenylate cyclase regulator activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0015173 aromatic amino acid transmembrane transporter activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0015205 nucleobase transmembrane transporter activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0019107 myristoyltransferase activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0019206 nucleoside kinase activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0034511 U3 snoRNA binding 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0042608 T cell receptor binding 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0043522 leucine zipper domain binding 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0047676 arachidonate-CoA ligase activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0070697 activin receptor binding 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0097493 structural molecule activity conferring elasticity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0180030 inositol phosphate kinase activity 3/3682 11/18639 0.272727272727273 1.38059848896351 0.374434182399915 0.768364172152965 GO:0008106 alcohol dehydrogenase (NADP+) activity 7/3682 30/18639 0.233333333333333 1.18117870722433 0.379784793696339 0.776964310768082 GO:0033612 receptor serine/threonine kinase binding 7/3682 30/18639 0.233333333333333 1.18117870722433 0.379784793696339 0.776964310768082 GO:0004843 cysteine-type deubiquitinase activity 23/3682 108/18639 0.212962962962963 1.07805993119681 0.380365601566034 0.776966320272081 GO:0005343 organic acid:sodium symporter activity 8/3682 35/18639 0.228571428571429 1.1570730193218 0.386329488036636 0.787947509846411 GO:0140098 catalytic activity, acting on RNA 79/3682 387/18639 0.204134366925065 1.03336786124831 0.391218534380774 0.794732156547151 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 9/3682 40/18639 0.225 1.13899375339489 0.391519625619906 0.794732156547151 GO:0015385 sodium:proton antiporter activity 4/3682 16/18639 0.25 1.26554861488322 0.392028324983333 0.794732156547151 GO:0022858 alanine transmembrane transporter activity 4/3682 16/18639 0.25 1.26554861488322 0.392028324983333 0.794732156547151 GO:0008009 chemokine activity 10/3682 45/18639 0.222222222222222 1.12493210211841 0.395738460382586 0.799833389008545 GO:0042605 peptide antigen binding 10/3682 45/18639 0.222222222222222 1.12493210211841 0.395738460382586 0.799833389008545 GO:0005006 epidermal growth factor receptor activity 11/3682 50/18639 0.22 1.11368278109723 0.399234049270474 0.802059409328989 GO:0005017 platelet-derived growth factor receptor activity 11/3682 50/18639 0.22 1.11368278109723 0.399234049270474 0.802059409328989 GO:0005019 platelet-derived growth factor beta-receptor activity 11/3682 50/18639 0.22 1.11368278109723 0.399234049270474 0.802059409328989 GO:0048020 CCR chemokine receptor binding 11/3682 50/18639 0.22 1.11368278109723 0.399234049270474 0.802059409328989 GO:0008374 O-acyltransferase activity 12/3682 55/18639 0.218181818181818 1.10447879117081 0.402174805753991 0.80545514005269 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/3682 21/18639 0.238095238095238 1.20528439512687 0.402727570026345 0.80545514005269 GO:0070182 DNA polymerase binding 5/3682 21/18639 0.238095238095238 1.20528439512687 0.402727570026345 0.80545514005269 GO:0008143 poly(A) binding 6/3682 26/18639 0.230769230769231 1.16819872143066 0.409984240748071 0.813894640892467 GO:0008157 protein phosphatase 1 binding 6/3682 26/18639 0.230769230769231 1.16819872143066 0.409984240748071 0.813894640892467 GO:0016289 acyl-CoA hydrolase activity 6/3682 26/18639 0.230769230769231 1.16819872143066 0.409984240748071 0.813894640892467 GO:0051139 metal cation:proton antiporter activity 6/3682 26/18639 0.230769230769231 1.16819872143066 0.409984240748071 0.813894640892467 GO:0120014 phospholipid transfer activity 6/3682 26/18639 0.230769230769231 1.16819872143066 0.409984240748071 0.813894640892467 GO:0008276 protein methyltransferase activity 20/3682 95/18639 0.210526315789474 1.06572514937534 0.415176013223924 0.820687169445669 GO:0017147 Wnt-protein binding 7/3682 31/18639 0.225806451612903 1.14307616828161 0.415243209615047 0.820687169445669 GO:0070273 phosphatidylinositol-4-phosphate binding 7/3682 31/18639 0.225806451612903 1.14307616828161 0.415243209615047 0.820687169445669 GO:0055106 ubiquitin-protein transferase regulator activity 8/3682 36/18639 0.222222222222222 1.12493210211841 0.419227126785244 0.827315437454995 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 27/3682 130/18639 0.207692307692308 1.05137884928759 0.4198317145294 0.827315437454995 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/3682 41/18639 0.219512195121951 1.11121341794624 0.422341726980903 0.829820988496203 GO:0140828 metal cation:monoatomic cation antiporter activity 9/3682 41/18639 0.219512195121951 1.11121341794624 0.422341726980903 0.829820988496203 GO:0019212 phosphatase inhibitor activity 12/3682 56/18639 0.214285714285714 1.08475595561418 0.428541341761684 0.83355539462396 GO:0170055 lipid transmembrane transporter activity 12/3682 56/18639 0.214285714285714 1.08475595561418 0.428541341761684 0.83355539462396 GO:0004857 enzyme inhibitor activity 84/3682 416/18639 0.201923076923077 1.02217388125183 0.430026988212194 0.83355539462396 GO:0004032 aldose reductase (NADPH) activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0010853 cyclase activator activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0015132 prostaglandin transmembrane transporter activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0034452 dynactin binding 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0035251 UDP-glucosyltransferase activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0035497 cAMP response element binding 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/3682 12/18639 0.25 1.26554861488322 0.432951160192743 0.83355539462396 GO:0004896 cytokine receptor activity 20/3682 96/18639 0.208333333333333 1.05462384573601 0.43531114854012 0.836719663293897 GO:0016779 nucleotidyltransferase activity 28/3682 136/18639 0.205882352941176 1.04221650637441 0.437178799726025 0.836719663293897 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0004550 nucleoside diphosphate kinase activity 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0015278 intracellularly gated calcium channel activity 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0015347 sodium-independent organic anion transmembrane transporter activity 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0016805 dipeptidase activity 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0030169 low-density lipoprotein particle binding 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0036041 long-chain fatty acid binding 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0046965 nuclear retinoid X receptor binding 4/3682 17/18639 0.235294117647059 1.19110457871361 0.440838867377233 0.836719663293897 GO:0016881 acid-amino acid ligase activity 5/3682 22/18639 0.227272727272727 1.15049874080292 0.445463795549594 0.841920290601489 GO:0031683 G-protein beta/gamma-subunit complex binding 5/3682 22/18639 0.227272727272727 1.15049874080292 0.445463795549594 0.841920290601489 GO:0140517 protein-RNA adaptor activity 5/3682 22/18639 0.227272727272727 1.15049874080292 0.445463795549594 0.841920290601489 GO:0001671 ATPase activator activity 6/3682 27/18639 0.222222222222222 1.12493210211841 0.448463993345009 0.844201278172487 GO:0005044 scavenger receptor activity 6/3682 27/18639 0.222222222222222 1.12493210211841 0.448463993345009 0.844201278172487 GO:0042393 histone binding 50/3682 247/18639 0.202429149797571 1.02473572055321 0.448560679148366 0.844201278172487 GO:0042910 xenobiotic transmembrane transporter activity 7/3682 32/18639 0.21875 1.10735503802281 0.450528068326002 0.84671474271647 GO:0019894 kinesin binding 9/3682 42/18639 0.214285714285714 1.08475595561418 0.453072979242188 0.850305031070773 GO:0015179 L-amino acid transmembrane transporter activity 13/3682 62/18639 0.209677419354839 1.06142787054721 0.455178683419851 0.852264649075851 GO:0016500 protein-hormone receptor activity 14/3682 67/18639 0.208955223880597 1.05777197661881 0.455389170700231 0.852264649075851 GO:0005201 extracellular matrix structural constituent 34/3682 168/18639 0.202380952380952 1.02449173585784 0.468070752653694 0.869582476135766 GO:0035091 phosphatidylinositol binding 57/3682 284/18639 0.200704225352113 1.0160038175823 0.470351308040808 0.869582476135766 GO:0004864 protein phosphatase inhibitor activity 11/3682 53/18639 0.207547169811321 1.05064413311059 0.481850775611044 0.869582476135766 GO:0005003 ephrin receptor activity 11/3682 53/18639 0.207547169811321 1.05064413311059 0.481850775611044 0.869582476135766 GO:0005005 transmembrane-ephrin receptor activity 11/3682 53/18639 0.207547169811321 1.05064413311059 0.481850775611044 0.869582476135766 GO:0005246 calcium channel regulator activity 11/3682 53/18639 0.207547169811321 1.05064413311059 0.481850775611044 0.869582476135766 GO:0038064 collagen receptor activity 11/3682 53/18639 0.207547169811321 1.05064413311059 0.481850775611044 0.869582476135766 GO:1901505 carbohydrate derivative transmembrane transporter activity 11/3682 53/18639 0.207547169811321 1.05064413311059 0.481850775611044 0.869582476135766 GO:0005501 retinoid binding 8/3682 38/18639 0.210526315789474 1.06572514937534 0.484437090117341 0.869582476135766 GO:0019840 isoprenoid binding 8/3682 38/18639 0.210526315789474 1.06572514937534 0.484437090117341 0.869582476135766 GO:0016866 intramolecular transferase activity 6/3682 28/18639 0.214285714285714 1.08475595561418 0.486361847098385 0.869582476135766 GO:0046966 nuclear thyroid hormone receptor binding 6/3682 28/18639 0.214285714285714 1.08475595561418 0.486361847098385 0.869582476135766 GO:0051393 alpha-actinin binding 6/3682 28/18639 0.214285714285714 1.08475595561418 0.486361847098385 0.869582476135766 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 6/3682 28/18639 0.214285714285714 1.08475595561418 0.486361847098385 0.869582476135766 GO:0141052 histone H3 demethylase activity 6/3682 28/18639 0.214285714285714 1.08475595561418 0.486361847098385 0.869582476135766 GO:0000295 adenine nucleotide transmembrane transporter activity 5/3682 23/18639 0.217391304347826 1.10047705642019 0.487380510275624 0.869582476135766 GO:0003887 DNA-directed DNA polymerase activity 5/3682 23/18639 0.217391304347826 1.10047705642019 0.487380510275624 0.869582476135766 GO:0004602 glutathione peroxidase activity 5/3682 23/18639 0.217391304347826 1.10047705642019 0.487380510275624 0.869582476135766 GO:0005158 insulin receptor binding 5/3682 23/18639 0.217391304347826 1.10047705642019 0.487380510275624 0.869582476135766 GO:0005283 amino acid:sodium symporter activity 5/3682 23/18639 0.217391304347826 1.10047705642019 0.487380510275624 0.869582476135766 GO:0140103 catalytic activity, acting on a glycoprotein 5/3682 23/18639 0.217391304347826 1.10047705642019 0.487380510275624 0.869582476135766 GO:0008525 phosphatidylcholine transporter activity 4/3682 18/18639 0.222222222222222 1.12493210211841 0.488402504373739 0.869582476135766 GO:0015172 acidic amino acid transmembrane transporter activity 4/3682 18/18639 0.222222222222222 1.12493210211841 0.488402504373739 0.869582476135766 GO:0016854 racemase and epimerase activity 4/3682 18/18639 0.222222222222222 1.12493210211841 0.488402504373739 0.869582476135766 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 4/3682 18/18639 0.222222222222222 1.12493210211841 0.488402504373739 0.869582476135766 GO:0017075 syntaxin-1 binding 4/3682 18/18639 0.222222222222222 1.12493210211841 0.488402504373739 0.869582476135766 GO:1901611 phosphatidylglycerol binding 4/3682 18/18639 0.222222222222222 1.12493210211841 0.488402504373739 0.869582476135766 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0008253 5'-nucleotidase activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0008417 fucosyltransferase activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0015651 quaternary ammonium group transmembrane transporter activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0017154 semaphorin receptor activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0045159 myosin II binding 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0046974 histone H3K9 methyltransferase activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0071714 icosanoid transmembrane transporter activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0089720 caspase binding 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0140852 histone ubiquitin ligase activity 3/3682 13/18639 0.230769230769231 1.16819872143066 0.489302378362961 0.869582476135766 GO:0016279 protein-lysine N-methyltransferase activity 14/3682 69/18639 0.202898550724638 1.02711191932551 0.503529582136218 0.892985832586189 GO:0101005 deubiquitinase activity 23/3682 115/18639 0.2 1.01243889190657 0.510982997768386 0.892985832586189 GO:0005004 GPI-linked ephrin receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0005008 hepatocyte growth factor receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0005009 insulin receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0005011 macrophage colony-stimulating factor receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0005018 platelet-derived growth factor alpha-receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0005020 stem cell factor receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0008288 boss receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0016763 pentosyltransferase activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0036332 placental growth factor receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0038062 protein tyrosine kinase collagen receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0060175 brain-derived neurotrophic factor receptor activity 10/3682 49/18639 0.204081632653061 1.03310091010875 0.511134428054931 0.892985832586189 GO:0016831 carboxy-lyase activity 7/3682 34/18639 0.205882352941176 1.04221650637441 0.519560001512359 0.904169353281248 GO:0030332 cyclin binding 7/3682 34/18639 0.205882352941176 1.04221650637441 0.519560001512359 0.904169353281248 GO:0090482 vitamin transmembrane transporter activity 7/3682 34/18639 0.205882352941176 1.04221650637441 0.519560001512359 0.904169353281248 GO:0005516 calmodulin binding 41/3682 207/18639 0.198067632850242 1.00265687362728 0.520484144451936 0.904602793210887 GO:0044325 transmembrane transporter binding 27/3682 136/18639 0.198529411764706 1.00499448828961 0.52294019267329 0.906086151235459 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 6/3682 29/18639 0.206896551724138 1.04735057783439 0.523385590612825 0.906086151235459 GO:0097472 cyclin-dependent protein kinase activity 6/3682 29/18639 0.206896551724138 1.04735057783439 0.523385590612825 0.906086151235459 GO:0044183 protein folding chaperone 15/3682 75/18639 0.2 1.01243889190657 0.524903207380833 0.906086151235459 GO:0016278 lysine N-methyltransferase activity 14/3682 70/18639 0.2 1.01243889190657 0.527235811448079 0.906086151235459 GO:0004622 lysophospholipase activity 5/3682 24/18639 0.208333333333333 1.05462384573601 0.528099465757383 0.906086151235459 GO:0005315 phosphate transmembrane transporter activity 5/3682 24/18639 0.208333333333333 1.05462384573601 0.528099465757383 0.906086151235459 GO:0005540 hyaluronic acid binding 5/3682 24/18639 0.208333333333333 1.05462384573601 0.528099465757383 0.906086151235459 GO:0035035 histone acetyltransferase binding 5/3682 24/18639 0.208333333333333 1.05462384573601 0.528099465757383 0.906086151235459 GO:0060229 lipase activator activity 5/3682 24/18639 0.208333333333333 1.05462384573601 0.528099465757383 0.906086151235459 GO:0019843 rRNA binding 13/3682 65/18639 0.2 1.01243889190657 0.529776162688046 0.906120223398744 GO:0003756 protein disulfide isomerase activity 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0005229 intracellularly calcium-gated chloride channel activity 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0022821 solute:potassium antiporter activity 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0042577 lipid phosphatase activity 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0046624 sphingolipid transporter activity 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0141147 intracellularly calcium-gated channel activity 4/3682 19/18639 0.210526315789474 1.06572514937534 0.534205206332095 0.906120223398744 GO:0140104 molecular carrier activity 49/3682 249/18639 0.196787148594378 0.996174813321728 0.537695189775137 0.910235805279382 GO:0005007 fibroblast growth factor receptor activity 10/3682 50/18639 0.2 1.01243889190657 0.539109522751045 0.910235805279382 GO:0050660 flavin adenine dinucleotide binding 17/3682 86/18639 0.197674418604651 1.00066634665184 0.542035048178742 0.910235805279382 GO:0005313 L-glutamate transmembrane transporter activity 3/3682 14/18639 0.214285714285714 1.08475595561418 0.542745080909124 0.910235805279382 GO:0008191 metalloendopeptidase inhibitor activity 3/3682 14/18639 0.214285714285714 1.08475595561418 0.542745080909124 0.910235805279382 GO:0008195 phosphatidate phosphatase activity 3/3682 14/18639 0.214285714285714 1.08475595561418 0.542745080909124 0.910235805279382 GO:0015386 potassium:proton antiporter activity 3/3682 14/18639 0.214285714285714 1.08475595561418 0.542745080909124 0.910235805279382 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 3/3682 14/18639 0.214285714285714 1.08475595561418 0.542745080909124 0.910235805279382 GO:0031404 chloride ion binding 3/3682 14/18639 0.214285714285714 1.08475595561418 0.542745080909124 0.910235805279382 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 24/3682 122/18639 0.19672131147541 0.995841533022858 0.545524152215526 0.913752954961006 GO:0032451 demethylase activity 8/3682 40/18639 0.2 1.01243889190657 0.547551270479234 0.914861224990241 GO:0071949 FAD binding 8/3682 40/18639 0.2 1.01243889190657 0.547551270479234 0.914861224990241 GO:0034061 DNA polymerase activity 7/3682 35/18639 0.2 1.01243889190657 0.55286762988129 0.921446049802149 GO:0043015 gamma-tubulin binding 7/3682 35/18639 0.2 1.01243889190657 0.55286762988129 0.921446049802149 GO:0019905 syntaxin binding 12/3682 61/18639 0.19672131147541 0.995841533022858 0.557696450785581 0.926381901592347 GO:0008187 poly-pyrimidine tract binding 6/3682 30/18639 0.2 1.01243889190657 0.559285789841947 0.926381901592347 GO:0016769 transferase activity, transferring nitrogenous groups 6/3682 30/18639 0.2 1.01243889190657 0.559285789841947 0.926381901592347 GO:0031210 phosphatidylcholine binding 6/3682 30/18639 0.2 1.01243889190657 0.559285789841947 0.926381901592347 GO:0032452 histone demethylase activity 6/3682 30/18639 0.2 1.01243889190657 0.559285789841947 0.926381901592347 GO:0015291 secondary active transmembrane transporter activity 56/3682 287/18639 0.195121951219512 0.987745260396656 0.565235276394136 0.930472396639437 GO:0005021 vascular endothelial growth factor receptor activity 10/3682 51/18639 0.196078431372549 0.992587148928012 0.566486353763218 0.930472396639437 GO:0005030 neurotrophin receptor activity 10/3682 51/18639 0.196078431372549 0.992587148928012 0.566486353763218 0.930472396639437 GO:0016830 carbon-carbon lyase activity 10/3682 51/18639 0.196078431372549 0.992587148928012 0.566486353763218 0.930472396639437 GO:0015645 fatty acid ligase activity 5/3682 25/18639 0.2 1.01243889190657 0.567310408995836 0.930472396639437 GO:0017056 structural constituent of nuclear pore 5/3682 25/18639 0.2 1.01243889190657 0.567310408995836 0.930472396639437 GO:0042974 nuclear retinoic acid receptor binding 5/3682 25/18639 0.2 1.01243889190657 0.567310408995836 0.930472396639437 GO:0120515 fatty acid-CoA ligase activity 5/3682 25/18639 0.2 1.01243889190657 0.567310408995836 0.930472396639437 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 9/3682 46/18639 0.195652173913043 0.990429350778169 0.571781693651726 0.936659498158084 GO:0140767 enzyme-substrate adaptor activity 27/3682 139/18639 0.194244604316547 0.983303959765376 0.573104647963107 0.93767375733609 GO:0005253 monoatomic anion channel activity 20/3682 103/18639 0.194174757281553 0.982950380491818 0.573800358966861 0.93767375733609 GO:0000339 RNA cap binding 4/3682 20/18639 0.2 1.01243889190657 0.577852143364095 0.938657979316578 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/3682 20/18639 0.2 1.01243889190657 0.577852143364095 0.938657979316578 GO:0031418 L-ascorbic acid binding 4/3682 20/18639 0.2 1.01243889190657 0.577852143364095 0.938657979316578 GO:0042288 MHC class I protein binding 4/3682 20/18639 0.2 1.01243889190657 0.577852143364095 0.938657979316578 GO:0042169 SH2 domain binding 8/3682 41/18639 0.195121951219512 0.987745260396656 0.577905099206102 0.938657979316578 GO:0004033 aldo-keto reductase (NADPH) activity 7/3682 36/18639 0.194444444444444 0.984315589353612 0.585125682352749 0.949235368465718 GO:0015932 nucleobase-containing compound transmembrane transporter activity 11/3682 57/18639 0.192982456140351 0.976914720260728 0.587412775347152 0.951304610019188 GO:0005523 tropomyosin binding 3/3682 15/18639 0.2 1.01243889190657 0.592778928119725 0.951304610019188 GO:0008252 nucleotidase activity 3/3682 15/18639 0.2 1.01243889190657 0.592778928119725 0.951304610019188 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 3/3682 15/18639 0.2 1.01243889190657 0.592778928119725 0.951304610019188 GO:0017081 chloride channel regulator activity 3/3682 15/18639 0.2 1.01243889190657 0.592778928119725 0.951304610019188 GO:0140161 monocarboxylate:sodium symporter activity 3/3682 15/18639 0.2 1.01243889190657 0.592778928119725 0.951304610019188 GO:0005164 tumor necrosis factor receptor binding 6/3682 31/18639 0.193548387096774 0.979779572812812 0.593856009096402 0.951304610019188 GO:0140457 protein demethylase activity 6/3682 31/18639 0.193548387096774 0.979779572812812 0.593856009096402 0.951304610019188 GO:0005504 fatty acid binding 9/3682 47/18639 0.191489361702128 0.969356385867995 0.599709736620296 0.951304610019188 GO:0008198 ferrous iron binding 5/3682 26/18639 0.192307692307692 0.973498934525551 0.6047690204834 0.951304610019188 GO:0015216 purine nucleotide transmembrane transporter activity 5/3682 26/18639 0.192307692307692 0.973498934525551 0.6047690204834 0.951304610019188 GO:0043548 phosphatidylinositol 3-kinase binding 5/3682 26/18639 0.192307692307692 0.973498934525551 0.6047690204834 0.951304610019188 GO:0035198 miRNA binding 8/3682 42/18639 0.19047619047619 0.964227516101498 0.607277362727023 0.951304610019188 GO:0140597 protein carrier chaperone 36/3682 188/18639 0.191489361702128 0.969356385867995 0.612090707465769 0.951304610019188 GO:0033293 monocarboxylic acid binding 15/3682 79/18639 0.189873417721519 0.961176163202442 0.612885848777432 0.951304610019188 GO:0005131 growth hormone receptor binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0008140 cAMP response element binding protein binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0008239 dipeptidyl-peptidase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0008519 ammonium channel activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0015643 toxic substance binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0016783 sulfurtransferase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0016868 intramolecular phosphotransferase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0030957 Tat protein binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0042975 peroxisome proliferator activated receptor binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0043121 neurotrophin binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0045322 unmethylated CpG binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0050308 sugar-phosphatase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0070513 death domain binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0140940 histone H2A methyltransferase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:1990259 histone H2AQ104 methyltransferase activity 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:1990763 arrestin family protein binding 2/3682 10/18639 0.2 1.01243889190657 0.616788143885174 0.951304610019188 GO:0003684 damaged DNA binding 14/3682 74/18639 0.189189189189189 0.957712465317028 0.617960134922121 0.951304610019188 GO:0005544 calcium-dependent phospholipid binding 10/3682 53/18639 0.188679245283019 0.95513103010054 0.619048999186958 0.951304610019188 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 4/3682 21/18639 0.19047619047619 0.964227516101498 0.61905792532592 0.951304610019188 GO:0005248 voltage-gated sodium channel activity 4/3682 21/18639 0.19047619047619 0.964227516101498 0.61905792532592 0.951304610019188 GO:0008373 sialyltransferase activity 4/3682 21/18639 0.19047619047619 0.964227516101498 0.61905792532592 0.951304610019188 GO:0009975 cyclase activity 4/3682 21/18639 0.19047619047619 0.964227516101498 0.61905792532592 0.951304610019188 GO:0051010 microtubule plus-end binding 4/3682 21/18639 0.19047619047619 0.964227516101498 0.61905792532592 0.951304610019188 GO:0015631 tubulin binding 74/3682 385/18639 0.192207792207792 0.97299322079333 0.625169436055915 0.954645979052127 GO:0038187 pattern recognition receptor activity 9/3682 48/18639 0.1875 0.949161461162412 0.626717421526488 0.954645979052127 GO:0015106 bicarbonate transmembrane transporter activity 6/3682 32/18639 0.1875 0.949161461162412 0.626931687735725 0.954645979052127 GO:0031369 translation initiation factor binding 6/3682 32/18639 0.1875 0.949161461162412 0.626931687735725 0.954645979052127 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/3682 32/18639 0.1875 0.949161461162412 0.626931687735725 0.954645979052127 GO:0043425 bHLH transcription factor binding 6/3682 32/18639 0.1875 0.949161461162412 0.626931687735725 0.954645979052127 GO:0071813 lipoprotein particle binding 6/3682 32/18639 0.1875 0.949161461162412 0.626931687735725 0.954645979052127 GO:0071814 protein-lipid complex binding 6/3682 32/18639 0.1875 0.949161461162412 0.626931687735725 0.954645979052127 GO:0003688 DNA replication origin binding 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0005149 interleukin-1 receptor binding 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0008142 oxysterol binding 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0008296 3'-5'-DNA exonuclease activity 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0019841 retinol binding 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0097027 ubiquitin-protein transferase activator activity 3/3682 16/18639 0.1875 0.949161461162412 0.639105990381969 0.961874969714525 GO:0004364 glutathione transferase activity 5/3682 27/18639 0.185185185185185 0.937443418432012 0.640292890287579 0.961874969714525 GO:0008266 poly(U) RNA binding 5/3682 27/18639 0.185185185185185 0.937443418432012 0.640292890287579 0.961874969714525 GO:0016405 CoA-ligase activity 5/3682 27/18639 0.185185185185185 0.937443418432012 0.640292890287579 0.961874969714525 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 5/3682 27/18639 0.185185185185185 0.937443418432012 0.640292890287579 0.961874969714525 GO:1901981 phosphatidylinositol phosphate binding 35/3682 185/18639 0.189189189189189 0.957712465317028 0.641916915635197 0.963234789418997 GO:0008509 monoatomic anion transmembrane transporter activity 28/3682 149/18639 0.187919463087248 0.951284864878659 0.6487282353965 0.972366706299004 GO:0141108 transporter regulator activity 32/3682 170/18639 0.188235294117647 0.952883662970892 0.65046150922439 0.973875332246573 GO:0140101 catalytic activity, acting on a tRNA 26/3682 139/18639 0.18705035971223 0.946885294588881 0.655725947957199 0.977871313267525 GO:0099106 ion channel regulator activity 30/3682 160/18639 0.1875 0.949161461162412 0.656709745614138 0.977871313267525 GO:0015377 chloride:monoatomic cation symporter activity 4/3682 22/18639 0.181818181818182 0.920398992642339 0.657634398609548 0.977871313267525 GO:0050321 tau-protein kinase activity 4/3682 22/18639 0.181818181818182 0.920398992642339 0.657634398609548 0.977871313267525 GO:0140035 ubiquitin-like protein reader activity 4/3682 22/18639 0.181818181818182 0.920398992642339 0.657634398609548 0.977871313267525 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 6/3682 33/18639 0.181818181818182 0.920398992642339 0.658387978873547 0.977871313267525 GO:0019956 chemokine binding 6/3682 33/18639 0.181818181818182 0.920398992642339 0.658387978873547 0.977871313267525 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 11/3682 60/18639 0.183333333333333 0.928068984247691 0.659758697573414 0.977871313267525 GO:0140034 methylation-dependent protein binding 14/3682 76/18639 0.184210526315789 0.932509505703422 0.660048192193379 0.977871313267525 GO:0043014 alpha-tubulin binding 8/3682 44/18639 0.181818181818182 0.920398992642339 0.662669274122514 0.977871313267525 GO:0046982 protein heterodimerization activity 70/3682 369/18639 0.18970189701897 0.960307892052305 0.669222747854207 0.977871313267525 GO:0004016 adenylate cyclase activity 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0008172 S-methyltransferase activity 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0008271 secondary active sulfate transmembrane transporter activity 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0008432 JUN kinase binding 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0019203 carbohydrate phosphatase activity 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0032794 GTPase activating protein binding 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0048407 platelet-derived growth factor binding 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0050998 nitric-oxide synthase binding 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0070990 snRNP binding 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0140031 phosphorylation-dependent protein binding 2/3682 11/18639 0.181818181818182 0.920398992642339 0.670644579770788 0.977871313267525 GO:0046625 sphingolipid binding 5/3682 28/18639 0.178571428571429 0.903963296345154 0.6737561605461 0.98027497842755 GO:0051959 dynein light intermediate chain binding 5/3682 28/18639 0.178571428571429 0.903963296345154 0.6737561605461 0.98027497842755 GO:0016798 hydrolase activity, acting on glycosyl bonds 24/3682 130/18639 0.184615384615385 0.934558977144529 0.67891936558983 0.983135646166753 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/3682 17/18639 0.176470588235294 0.893328434035211 0.681591802454413 0.983135646166753 GO:0030548 acetylcholine receptor regulator activity 3/3682 17/18639 0.176470588235294 0.893328434035211 0.681591802454413 0.983135646166753 GO:0045125 bioactive lipid receptor activity 3/3682 17/18639 0.176470588235294 0.893328434035211 0.681591802454413 0.983135646166753 GO:0070402 NADPH binding 3/3682 17/18639 0.176470588235294 0.893328434035211 0.681591802454413 0.983135646166753 GO:0070403 NAD+ binding 3/3682 17/18639 0.176470588235294 0.893328434035211 0.681591802454413 0.983135646166753 GO:0070492 oligosaccharide binding 3/3682 17/18639 0.176470588235294 0.893328434035211 0.681591802454413 0.983135646166753 GO:1990226 histone methyltransferase binding 3/3682 17/18639 0.176470588235294 0.893328434035211 0.681591802454413 0.983135646166753 GO:0042379 chemokine receptor binding 13/3682 72/18639 0.180555555555556 0.914007332971211 0.687271442140584 0.989381280859881 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 6/3682 34/18639 0.176470588235294 0.893328434035211 0.688136831165231 0.989381280859881 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 6/3682 34/18639 0.176470588235294 0.893328434035211 0.688136831165231 0.989381280859881 GO:0046906 tetrapyrrole binding 28/3682 152/18639 0.184210526315789 0.932509505703422 0.692008498402912 0.993881444651557 GO:0031681 G-protein beta-subunit binding 4/3682 23/18639 0.173913043478261 0.88038164513615 0.693477322469321 0.99430569654735 GO:0043177 organic acid binding 35/3682 189/18639 0.185185185185185 0.937443418432012 0.693982074396939 0.99430569654735 GO:0016247 channel regulator activity 31/3682 168/18639 0.18452380952381 0.934095406223326 0.694529949230089 0.99430569654735 GO:0050997 quaternary ammonium group binding 7/3682 40/18639 0.175 0.885884030418251 0.701170552245498 1 GO:0140662 ATP-dependent protein folding chaperone 7/3682 40/18639 0.175 0.885884030418251 0.701170552245498 1 GO:0016597 amino acid binding 9/3682 51/18639 0.176470588235294 0.893328434035211 0.701486894259869 1 GO:0005416 amino acid:monoatomic cation symporter activity 5/3682 29/18639 0.172413793103448 0.872792148195321 0.705083362615532 1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/3682 29/18639 0.172413793103448 0.872792148195321 0.705083362615532 1 GO:0106222 lncRNA binding 5/3682 29/18639 0.172413793103448 0.872792148195321 0.705083362615532 1 GO:0008514 organic anion transmembrane transporter activity 50/3682 269/18639 0.185873605947955 0.940928338203134 0.709113519492699 1 GO:0016229 steroid dehydrogenase activity 6/3682 35/18639 0.171428571428571 0.867804764491348 0.716123562465356 1 GO:0015370 solute:sodium symporter activity 14/3682 79/18639 0.177215189873418 0.897097752322279 0.718139804387021 1 GO:0003720 telomerase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0003995 acyl-CoA dehydrogenase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0004000 adenosine deaminase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0004300 enoyl-CoA hydratase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0005049 nuclear export signal receptor activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0005436 sodium:phosphate symporter activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0015269 calcium-activated potassium channel activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0016840 carbon-nitrogen lyase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0031543 peptidyl-proline dioxygenase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0035197 siRNA binding 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0036009 protein-glutamine N-methyltransferase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0070679 inositol 1,4,5 trisphosphate binding 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:1990459 transferrin receptor binding 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:1990817 poly(A) RNA polymerase activity 2/3682 12/18639 0.166666666666667 0.84369907658881 0.718183263686396 1 GO:0000400 four-way junction DNA binding 3/3682 18/18639 0.166666666666667 0.84369907658881 0.720229662070548 1 GO:0003746 translation elongation factor activity 3/3682 18/18639 0.166666666666667 0.84369907658881 0.720229662070548 1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/3682 18/18639 0.166666666666667 0.84369907658881 0.720229662070548 1 GO:0099602 neurotransmitter receptor regulator activity 3/3682 18/18639 0.166666666666667 0.84369907658881 0.720229662070548 1 GO:0035064 methylated histone binding 13/3682 74/18639 0.175675675675676 0.889304432080098 0.726027397799199 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 7/3682 41/18639 0.170731707317073 0.864277102847074 0.726548733753609 1 GO:0016877 ligase activity, forming carbon-sulfur bonds 7/3682 41/18639 0.170731707317073 0.864277102847074 0.726548733753609 1 GO:0019957 C-C chemokine binding 4/3682 24/18639 0.166666666666667 0.84369907658881 0.726552893811709 1 GO:0001664 G protein-coupled receptor binding 55/3682 297/18639 0.185185185185185 0.937443418432012 0.726930517734986 1 GO:0031406 carboxylic acid binding 34/3682 187/18639 0.181818181818182 0.920398992642339 0.733679284362455 1 GO:0001965 G-protein alpha-subunit binding 5/3682 30/18639 0.166666666666667 0.84369907658881 0.734242877170249 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 5/3682 30/18639 0.166666666666667 0.84369907658881 0.734242877170249 1 GO:0015215 nucleotide transmembrane transporter activity 5/3682 30/18639 0.166666666666667 0.84369907658881 0.734242877170249 1 GO:0070566 adenylyltransferase activity 5/3682 30/18639 0.166666666666667 0.84369907658881 0.734242877170249 1 GO:0017116 single-stranded DNA helicase activity 10/3682 58/18639 0.172413793103448 0.872792148195321 0.734433072162624 1 GO:0061980 regulatory RNA binding 10/3682 58/18639 0.172413793103448 0.872792148195321 0.734433072162624 1 GO:0019842 vitamin binding 27/3682 150/18639 0.18 0.911195002715915 0.736478564299116 1 GO:0004536 DNA nuclease activity 11/3682 64/18639 0.171875 0.870064672732211 0.744041691393677 1 GO:0004520 DNA endonuclease activity 7/3682 42/18639 0.166666666666667 0.84369907658881 0.750403007958927 1 GO:0008083 growth factor activity 29/3682 162/18639 0.179012345679012 0.906195304484278 0.75290660960468 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 12/3682 70/18639 0.171428571428571 0.867804764491348 0.753067019762022 1 GO:0052689 carboxylic ester hydrolase activity 16/3682 92/18639 0.173913043478261 0.88038164513615 0.754328453098881 1 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 10/3682 59/18639 0.169491525423729 0.857999060937773 0.754431715519051 1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/3682 19/18639 0.157894736842105 0.799293862031505 0.755109247521507 1 GO:0016918 retinal binding 3/3682 19/18639 0.157894736842105 0.799293862031505 0.755109247521507 1 GO:0034987 immunoglobulin receptor binding 3/3682 19/18639 0.157894736842105 0.799293862031505 0.755109247521507 1 GO:0097001 ceramide binding 3/3682 19/18639 0.157894736842105 0.799293862031505 0.755109247521507 1 GO:0120227 acyl-CoA binding 3/3682 19/18639 0.157894736842105 0.799293862031505 0.755109247521507 1 GO:0140036 ubiquitin-modified protein reader activity 3/3682 19/18639 0.157894736842105 0.799293862031505 0.755109247521507 1 GO:0001848 complement binding 4/3682 25/18639 0.16 0.809951113525258 0.756884795681399 1 GO:0005537 D-mannose binding 4/3682 25/18639 0.16 0.809951113525258 0.756884795681399 1 GO:0008483 transaminase activity 4/3682 25/18639 0.16 0.809951113525258 0.756884795681399 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 4/3682 25/18639 0.16 0.809951113525258 0.756884795681399 1 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 4/3682 25/18639 0.16 0.809951113525258 0.756884795681399 1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 8/3682 48/18639 0.166666666666667 0.84369907658881 0.758312623517966 1 GO:0003964 RNA-directed DNA polymerase activity 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0008035 high-density lipoprotein particle binding 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0019104 DNA N-glycosylase activity 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0031432 titin binding 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0035673 oligopeptide transmembrane transporter activity 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0061459 L-arginine transmembrane transporter activity 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0097157 pre-mRNA intronic binding 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0140666 annealing activity 2/3682 13/18639 0.153846153846154 0.77879914762044 0.759797970108839 1 GO:0005452 solute:inorganic anion antiporter activity 5/3682 31/18639 0.161290322580645 0.81648297734401 0.761240351799835 1 GO:0016878 acid-thiol ligase activity 5/3682 31/18639 0.161290322580645 0.81648297734401 0.761240351799835 1 GO:0072349 modified amino acid transmembrane transporter activity 5/3682 31/18639 0.161290322580645 0.81648297734401 0.761240351799835 1 GO:1901681 sulfur compound binding 50/3682 275/18639 0.181818181818182 0.920398992642339 0.767059886638881 1 GO:0140299 molecular sensor activity 12/3682 71/18639 0.169014084507042 0.855582162174568 0.770625493791713 1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 10/3682 60/18639 0.166666666666667 0.84369907658881 0.773366319108179 1 GO:0015081 sodium ion transmembrane transporter activity 29/3682 164/18639 0.176829268292683 0.89514414223447 0.776243834243811 1 GO:0004529 DNA exonuclease activity 4/3682 26/18639 0.153846153846154 0.77879914762044 0.784542209353763 1 GO:0030247 polysaccharide binding 4/3682 26/18639 0.153846153846154 0.77879914762044 0.784542209353763 1 GO:0070006 metalloaminopeptidase activity 4/3682 26/18639 0.153846153846154 0.77879914762044 0.784542209353763 1 GO:0008135 translation factor activity, RNA binding 14/3682 83/18639 0.168674698795181 0.853864125704338 0.785259779459158 1 GO:0015294 solute:monoatomic cation symporter activity 20/3682 116/18639 0.172413793103448 0.872792148195321 0.785333606065342 1 GO:0010851 cyclase regulator activity 3/3682 20/18639 0.15 0.759329168929929 0.78638991296105 1 GO:0030742 GTP-dependent protein binding 3/3682 20/18639 0.15 0.759329168929929 0.78638991296105 1 GO:0015103 inorganic anion transmembrane transporter activity 29/3682 165/18639 0.175757575757576 0.889719026220927 0.78735302832572 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/3682 14/18639 0.142857142857143 0.723170637076123 0.795973451642125 1 GO:0032454 histone H3K9 demethylase activity 2/3682 14/18639 0.142857142857143 0.723170637076123 0.795973451642125 1 GO:1901474 azole transmembrane transporter activity 2/3682 14/18639 0.142857142857143 0.723170637076123 0.795973451642125 1 GO:0180051 translation factor activity 14/3682 84/18639 0.166666666666667 0.84369907658881 0.800138865810771 1 GO:0030170 pyridoxal phosphate binding 9/3682 56/18639 0.160714285714286 0.813566966710639 0.803083584752715 1 GO:0019239 deaminase activity 5/3682 33/18639 0.151515151515152 0.766999160535282 0.808920245868124 1 GO:0030296 protein tyrosine kinase activator activity 5/3682 33/18639 0.151515151515152 0.766999160535282 0.808920245868124 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 4/3682 27/18639 0.148148148148148 0.749954734745609 0.809629047452229 1 GO:0016829 lyase activity 35/3682 200/18639 0.175 0.885884030418251 0.813524929695102 1 GO:0001846 opsonin binding 3/3682 21/18639 0.142857142857143 0.723170637076123 0.814278577566906 1 GO:0015174 basic amino acid transmembrane transporter activity 3/3682 21/18639 0.142857142857143 0.723170637076123 0.814278577566906 1 GO:0003743 translation initiation factor activity 8/3682 51/18639 0.156862745098039 0.79406971914241 0.816194883483754 1 GO:0015171 amino acid transmembrane transporter activity 17/3682 102/18639 0.166666666666667 0.84369907658881 0.817564254712918 1 GO:0048029 monosaccharide binding 12/3682 74/18639 0.162162162162162 0.820896398843167 0.817998081290543 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 15/3682 91/18639 0.164835164835165 0.834427658164758 0.819587976093511 1 GO:0072341 modified amino acid binding 15/3682 91/18639 0.164835164835165 0.834427658164758 0.819587976093511 1 GO:0004601 peroxidase activity 9/3682 57/18639 0.157894736842105 0.799293862031505 0.819903676939715 1 GO:0070279 vitamin B6 binding 9/3682 57/18639 0.157894736842105 0.799293862031505 0.819903676939715 1 GO:0008017 microtubule binding 49/3682 276/18639 0.177536231884058 0.89872292940982 0.819905081926593 1 GO:0004953 icosanoid receptor activity 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0010181 FMN binding 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0015116 sulfate transmembrane transporter activity 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0033130 acetylcholine receptor binding 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0034483 heparan sulfate sulfotransferase activity 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0045504 dynein heavy chain binding 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0047372 monoacylglycerol lipase activity 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/3682 15/18639 0.133333333333333 0.674959261271048 0.827234147568648 1 GO:0016209 antioxidant activity 14/3682 86/18639 0.162790697674419 0.824078167830931 0.827639758662318 1 GO:0005243 gap junction channel activity 3/3682 22/18639 0.136363636363636 0.690299244481754 0.839011868981225 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/3682 22/18639 0.136363636363636 0.690299244481754 0.839011868981225 1 GO:0033691 sialic acid binding 3/3682 22/18639 0.136363636363636 0.690299244481754 0.839011868981225 1 GO:0051213 dioxygenase activity 15/3682 93/18639 0.161290322580645 0.81648297734401 0.844330905791634 1 GO:0042287 MHC protein binding 6/3682 41/18639 0.146341463414634 0.740808945297492 0.847234748897921 1 GO:1990518 single-stranded 3'-5' DNA helicase activity 7/3682 47/18639 0.148936170212766 0.753943855675107 0.847337822071565 1 GO:0099604 ligand-gated calcium channel activity 4/3682 29/18639 0.137931034482759 0.698233718556257 0.852625115161286 1 GO:0000062 fatty-acyl-CoA binding 2/3682 16/18639 0.125 0.632774307441608 0.854109598595316 1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/3682 16/18639 0.125 0.632774307441608 0.854109598595316 1 GO:0015378 sodium:chloride symporter activity 2/3682 16/18639 0.125 0.632774307441608 0.854109598595316 1 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/3682 16/18639 0.125 0.632774307441608 0.854109598595316 1 GO:0042562 hormone binding 15/3682 94/18639 0.159574468085106 0.807796988223329 0.855692682723179 1 GO:0005254 chloride channel activity 13/3682 83/18639 0.156626506024096 0.792873831011171 0.860510890481374 1 GO:0016849 phosphorus-oxygen lyase activity 3/3682 23/18639 0.130434782608696 0.660286233852112 0.860842050958011 1 GO:0017134 fibroblast growth factor binding 3/3682 23/18639 0.130434782608696 0.660286233852112 0.860842050958011 1 GO:0043274 phospholipase binding 3/3682 23/18639 0.130434782608696 0.660286233852112 0.860842050958011 1 GO:0016879 ligase activity, forming carbon-nitrogen bonds 7/3682 48/18639 0.145833333333333 0.738236692015209 0.862537246214863 1 GO:0032266 phosphatidylinositol-3-phosphate binding 7/3682 48/18639 0.145833333333333 0.738236692015209 0.862537246214863 1 GO:0043138 3'-5' DNA helicase activity 7/3682 48/18639 0.145833333333333 0.738236692015209 0.862537246214863 1 GO:0061135 endopeptidase regulator activity 31/3682 184/18639 0.168478260869565 0.852869718725645 0.862669932332464 1 GO:0050661 NADP binding 8/3682 54/18639 0.148148148148148 0.749954734745609 0.8627850554951 1 GO:0051287 NAD binding 8/3682 54/18639 0.148148148148148 0.749954734745609 0.8627850554951 1 GO:0008307 structural constituent of muscle 6/3682 42/18639 0.142857142857143 0.723170637076123 0.863373372387754 1 GO:0004190 aspartic-type endopeptidase activity 5/3682 36/18639 0.138888888888889 0.703082563824009 0.865836509015872 1 GO:0045505 dynein intermediate chain binding 5/3682 36/18639 0.138888888888889 0.703082563824009 0.865836509015872 1 GO:0015293 symporter activity 24/3682 146/18639 0.164383561643836 0.832141554991703 0.868824326605873 1 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/3682 17/18639 0.117647058823529 0.595552289356807 0.877111971414104 1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/3682 17/18639 0.117647058823529 0.595552289356807 0.877111971414104 1 GO:0008484 sulfuric ester hydrolase activity 2/3682 17/18639 0.117647058823529 0.595552289356807 0.877111971414104 1 GO:0016018 cyclosporin A binding 2/3682 17/18639 0.117647058823529 0.595552289356807 0.877111971414104 1 GO:1901567 fatty acid derivative binding 2/3682 17/18639 0.117647058823529 0.595552289356807 0.877111971414104 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/3682 24/18639 0.125 0.632774307441608 0.880026216264626 1 GO:0022829 wide pore channel activity 5/3682 37/18639 0.135135135135135 0.684080332369306 0.881320911468608 1 GO:0070001 aspartic-type peptidase activity 5/3682 37/18639 0.135135135135135 0.684080332369306 0.881320911468608 1 GO:0020037 heme binding 23/3682 142/18639 0.161971830985915 0.819932905417295 0.881810967828178 1 GO:0061134 peptidase regulator activity 38/3682 226/18639 0.168141592920354 0.851165440098446 0.886746005893499 1 GO:0004935 adrenergic receptor activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0005337 nucleoside transmembrane transporter activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0005381 iron ion transmembrane transporter activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0008401 retinoic acid 4-hydroxylase activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0015187 glycine transmembrane transporter activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0019531 oxalate transmembrane transporter activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0032052 bile acid binding 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0032356 oxidized DNA binding 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0032395 MHC class II receptor activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0035256 G protein-coupled glutamate receptor binding 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0042166 acetylcholine binding 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0051880 G-quadruplex DNA binding 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0141109 transporter activator activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:1990757 ubiquitin ligase activator activity 1/3682 10/18639 0.1 0.506219445953286 0.889347650571697 1 GO:0000049 tRNA binding 12/3682 80/18639 0.15 0.759329168929929 0.890204566653382 1 GO:0046943 carboxylic acid transmembrane transporter activity 31/3682 188/18639 0.164893617021277 0.83472355449744 0.891134061525502 1 GO:0015108 chloride transmembrane transporter activity 19/3682 121/18639 0.15702479338843 0.794890039100202 0.894754896262302 1 GO:0000146 microfilament motor activity 5/3682 38/18639 0.131578947368421 0.666078218359587 0.895250456588328 1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/3682 18/18639 0.111111111111111 0.562466051059207 0.896722260082048 1 GO:0015280 ligand-gated sodium channel activity 2/3682 18/18639 0.111111111111111 0.562466051059207 0.896722260082048 1 GO:0015373 monoatomic anion:sodium symporter activity 2/3682 18/18639 0.111111111111111 0.562466051059207 0.896722260082048 1 GO:0034185 apolipoprotein binding 2/3682 18/18639 0.111111111111111 0.562466051059207 0.896722260082048 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/3682 25/18639 0.12 0.607463335143943 0.896818228162338 1 GO:0005342 organic acid transmembrane transporter activity 31/3682 189/18639 0.164021164021164 0.830307027754067 0.897475378468147 1 GO:0016874 ligase activity 27/3682 167/18639 0.161676646706587 0.818438625193936 0.899842913904513 1 GO:0005272 sodium channel activity 7/3682 51/18639 0.137254901960784 0.694811004249609 0.900833347369223 1 GO:0008237 metallopeptidase activity 30/3682 184/18639 0.16304347826087 0.825357792315141 0.901048572958063 1 GO:1902936 phosphatidylinositol bisphosphate binding 17/3682 111/18639 0.153153153153153 0.77529104335188 0.906141603516544 1 GO:0001851 complement component C3b binding 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0008199 ferric iron binding 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0008526 phosphatidylinositol transfer activity 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0016594 glycine binding 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0019215 intermediate filament binding 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0019864 IgG binding 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0032404 mismatch repair complex binding 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0050786 RAGE receptor binding 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:1990948 ubiquitin ligase inhibitor activity 1/3682 11/18639 0.0909090909090909 0.460199496321169 0.911217957651787 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/3682 52/18639 0.134615384615385 0.681449254167885 0.911396307801841 1 GO:0005227 calcium-activated cation channel activity 3/3682 26/18639 0.115384615384615 0.58409936071533 0.911462926267805 1 GO:0008066 glutamate receptor activity 3/3682 26/18639 0.115384615384615 0.58409936071533 0.911462926267805 1 GO:0019865 immunoglobulin binding 3/3682 26/18639 0.115384615384615 0.58409936071533 0.911462926267805 1 GO:0052742 phosphatidylinositol kinase activity 3/3682 26/18639 0.115384615384615 0.58409936071533 0.911462926267805 1 GO:0042834 peptidoglycan binding 2/3682 19/18639 0.105263157894737 0.53286257468767 0.913382614500935 1 GO:0070003 threonine-type peptidase activity 2/3682 19/18639 0.105263157894737 0.53286257468767 0.913382614500935 1 GO:0001786 phosphatidylserine binding 8/3682 59/18639 0.135593220338983 0.686399248750219 0.918794172948148 1 GO:0015459 potassium channel regulator activity 8/3682 59/18639 0.135593220338983 0.686399248750219 0.918794172948148 1 GO:0036002 pre-mRNA binding 8/3682 59/18639 0.135593220338983 0.686399248750219 0.918794172948148 1 GO:0004177 aminopeptidase activity 5/3682 40/18639 0.125 0.632774307441608 0.918908106074706 1 GO:0017046 peptide hormone binding 7/3682 53/18639 0.132075471698113 0.668591721070378 0.920976136890548 1 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/3682 27/18639 0.111111111111111 0.562466051059207 0.924192161119752 1 GO:0008320 protein transmembrane transporter activity 3/3682 27/18639 0.111111111111111 0.562466051059207 0.924192161119752 1 GO:0008395 steroid hydroxylase activity 3/3682 27/18639 0.111111111111111 0.562466051059207 0.924192161119752 1 GO:0061749 forked DNA-dependent helicase activity 6/3682 47/18639 0.127659574468085 0.646237590578663 0.924211514583041 1 GO:0015020 glucuronosyltransferase activity 4/3682 34/18639 0.117647058823529 0.595552289356807 0.925536450448325 1 GO:0051427 hormone receptor binding 4/3682 34/18639 0.117647058823529 0.595552289356807 0.925536450448325 1 GO:0005326 neurotransmitter transmembrane transporter activity 2/3682 20/18639 0.1 0.506219445953286 0.927492914672033 1 GO:0016408 C-acyltransferase activity 2/3682 20/18639 0.1 0.506219445953286 0.927492914672033 1 GO:0043024 ribosomal small subunit binding 2/3682 20/18639 0.1 0.506219445953286 0.927492914672033 1 GO:0004126 cytidine deaminase activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0005078 MAP-kinase scaffold activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0005165 neurotrophin receptor binding 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0008179 adenylate cyclase binding 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0008504 monoamine transmembrane transporter activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0015166 polyol transmembrane transporter activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0015368 calcium:monoatomic cation antiporter activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0097371 MDM2/MDM4 family protein binding 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0140900 chloride:bicarbonate antiporter activity 1/3682 12/18639 0.0833333333333333 0.421849538294405 0.928766566194096 1 GO:0140463 chromatin-protein adaptor activity 7/3682 54/18639 0.12962962962963 0.656210392902408 0.929642893694125 1 GO:0009378 four-way junction helicase activity 6/3682 48/18639 0.125 0.632774307441608 0.933022124349924 1 GO:0036121 double-stranded DNA helicase activity 6/3682 48/18639 0.125 0.632774307441608 0.933022124349924 1 GO:0140693 molecular condensate scaffold activity 6/3682 48/18639 0.125 0.632774307441608 0.933022124349924 1 GO:0030246 carbohydrate binding 46/3682 280/18639 0.164285714285714 0.831646232637542 0.933700283328829 1 GO:0050698 proteoglycan sulfotransferase activity 3/3682 28/18639 0.107142857142857 0.542377977807092 0.935222277021732 1 GO:0140566 histone reader activity 4/3682 35/18639 0.114285714285714 0.578536509660899 0.935453169961616 1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 12/3682 86/18639 0.13953488372093 0.706352715283655 0.937128496812472 1 GO:0004222 metalloendopeptidase activity 16/3682 110/18639 0.145454545454545 0.736319194113871 0.937259909951212 1 GO:0031492 nucleosomal DNA binding 5/3682 42/18639 0.119047619047619 0.602642197563436 0.937712653425139 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 18/3682 122/18639 0.147540983606557 0.746881149767144 0.938252438610201 1 GO:0003678 DNA helicase activity 10/3682 74/18639 0.135135135135135 0.684080332369306 0.938630621351554 1 GO:0031491 nucleosome binding 10/3682 74/18639 0.135135135135135 0.684080332369306 0.938630621351554 1 GO:0010314 phosphatidylinositol-5-phosphate binding 2/3682 21/18639 0.0952380952380952 0.482113758050749 0.939410213314678 1 GO:0015125 bile acid transmembrane transporter activity 2/3682 21/18639 0.0952380952380952 0.482113758050749 0.939410213314678 1 GO:0019200 carbohydrate kinase activity 2/3682 21/18639 0.0952380952380952 0.482113758050749 0.939410213314678 1 GO:0036122 BMP binding 2/3682 21/18639 0.0952380952380952 0.482113758050749 0.939410213314678 1 GO:0140674 ATP-dependent histone chaperone activity 23/3682 152/18639 0.151315789473684 0.765989951113525 0.942060461365957 1 GO:0004465 lipoprotein lipase activity 1/3682 13/18639 0.0769230769230769 0.38939957381022 0.942847282534534 1 GO:0005542 folic acid binding 1/3682 13/18639 0.0769230769230769 0.38939957381022 0.942847282534534 1 GO:0039706 co-receptor binding 1/3682 13/18639 0.0769230769230769 0.38939957381022 0.942847282534534 1 GO:0043560 insulin receptor substrate binding 1/3682 13/18639 0.0769230769230769 0.38939957381022 0.942847282534534 1 GO:0071837 HMG box domain binding 1/3682 13/18639 0.0769230769230769 0.38939957381022 0.942847282534534 1 GO:0008081 phosphoric diester hydrolase activity 12/3682 87/18639 0.137931034482759 0.698233718556257 0.942975166932045 1 GO:0140713 histone chaperone activity 25/3682 164/18639 0.152439024390244 0.771675984684888 0.943866689795548 1 GO:0003774 cytoskeletal motor activity 23/3682 153/18639 0.150326797385621 0.760983480844809 0.94631553923727 1 GO:0008970 phospholipase A1 activity 2/3682 22/18639 0.0909090909090909 0.460199496321169 0.949450047748024 1 GO:0140784 metal ion sensor activity 2/3682 22/18639 0.0909090909090909 0.460199496321169 0.949450047748024 1 GO:0005506 iron ion binding 23/3682 154/18639 0.149350649350649 0.756042029670492 0.950301545589296 1 GO:0003689 DNA clamp loader activity 24/3682 160/18639 0.15 0.759329168929929 0.950953383441562 1 GO:0030547 signaling receptor inhibitor activity 5/3682 44/18639 0.113636363636364 0.575249370401462 0.952501664347295 1 GO:0004867 serine-type endopeptidase inhibitor activity 13/3682 95/18639 0.136842105263158 0.692721347093971 0.952618768277884 1 GO:0022839 monoatomic ion-gated channel activity 3/3682 30/18639 0.1 0.506219445953286 0.952965491176522 1 GO:0048019 receptor antagonist activity 3/3682 30/18639 0.1 0.506219445953286 0.952965491176522 1 GO:0004065 arylsulfatase activity 1/3682 14/18639 0.0714285714285714 0.361585318538062 0.954145269526258 1 GO:0008494 translation activator activity 1/3682 14/18639 0.0714285714285714 0.361585318538062 0.954145269526258 1 GO:0019763 immunoglobulin receptor activity 1/3682 14/18639 0.0714285714285714 0.361585318538062 0.954145269526258 1 GO:0030983 mismatched DNA binding 1/3682 14/18639 0.0714285714285714 0.361585318538062 0.954145269526258 1 GO:0042043 neurexin family protein binding 1/3682 14/18639 0.0714285714285714 0.361585318538062 0.954145269526258 1 GO:0004866 endopeptidase inhibitor activity 24/3682 161/18639 0.149068322981366 0.754612838688129 0.954580500688744 1 GO:0005539 glycosaminoglycan binding 38/3682 242/18639 0.15702479338843 0.794890039100202 0.956147867791322 1 GO:0140375 immune receptor activity 23/3682 156/18639 0.147435897435897 0.746349183136255 0.957517704963036 1 GO:0005212 structural constituent of eye lens 2/3682 23/18639 0.0869565217391304 0.440190822568075 0.957888904585168 1 GO:0016493 C-C chemokine receptor activity 2/3682 23/18639 0.0869565217391304 0.440190822568075 0.957888904585168 1 GO:0099186 structural constituent of postsynapse 2/3682 23/18639 0.0869565217391304 0.440190822568075 0.957888904585168 1 GO:0042887 amide transmembrane transporter activity 4/3682 38/18639 0.105263157894737 0.53286257468767 0.958421075146488 1 GO:0008327 methyl-CpG binding 3/3682 31/18639 0.0967741935483871 0.489889786406406 0.96002524866465 1 GO:0047499 calcium-independent phospholipase A2 activity 3/3682 31/18639 0.0967741935483871 0.489889786406406 0.96002524866465 1 GO:0000510 H3-H4 histone complex chaperone activity 22/3682 151/18639 0.145695364238411 0.737538265627304 0.960442455899506 1 GO:0140584 chromatin extrusion motor activity 22/3682 151/18639 0.145695364238411 0.737538265627304 0.960442455899506 1 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 22/3682 151/18639 0.145695364238411 0.737538265627304 0.960442455899506 1 GO:0140849 ATP-dependent H2AZ histone chaperone activity 22/3682 151/18639 0.145695364238411 0.737538265627304 0.960442455899506 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/3682 15/18639 0.0666666666666667 0.337479630635524 0.963210349666087 1 GO:0008242 omega peptidase activity 1/3682 15/18639 0.0666666666666667 0.337479630635524 0.963210349666087 1 GO:0015250 water channel activity 1/3682 15/18639 0.0666666666666667 0.337479630635524 0.963210349666087 1 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/3682 15/18639 0.0666666666666667 0.337479630635524 0.963210349666087 1 GO:0030553 cGMP binding 1/3682 15/18639 0.0666666666666667 0.337479630635524 0.963210349666087 1 GO:0015616 DNA translocase activity 22/3682 152/18639 0.144736842105263 0.732686040195546 0.963553254974414 1 GO:0140658 ATP-dependent chromatin remodeler activity 23/3682 158/18639 0.145569620253165 0.736901725121872 0.963809153353223 1 GO:0008146 sulfotransferase activity 6/3682 53/18639 0.113207547169811 0.573078618060324 0.964795598792422 1 GO:0004806 triacylglycerol lipase activity 2/3682 24/18639 0.0833333333333333 0.421849538294405 0.964967330796126 1 GO:0140612 DNA damage sensor activity 2/3682 24/18639 0.0833333333333333 0.421849538294405 0.964967330796126 1 GO:0022884 macromolecule transmembrane transporter activity 3/3682 32/18639 0.09375 0.474580730581206 0.966079835319533 1 GO:0047498 calcium-dependent phospholipase A2 activity 3/3682 32/18639 0.09375 0.474580730581206 0.966079835319533 1 GO:0061775 cohesin loader activity 22/3682 153/18639 0.143790849673203 0.727897242547209 0.966448138533324 1 GO:0071855 neuropeptide receptor binding 4/3682 40/18639 0.1 0.506219445953286 0.969246936437336 1 GO:0016722 oxidoreductase activity, acting on metal ions 1/3682 16/18639 0.0625 0.316387153720804 0.970483733070805 1 GO:0022841 potassium ion leak channel activity 1/3682 16/18639 0.0625 0.316387153720804 0.970483733070805 1 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/3682 16/18639 0.0625 0.316387153720804 0.970483733070805 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/3682 16/18639 0.0625 0.316387153720804 0.970483733070805 1 GO:0055102 lipase inhibitor activity 1/3682 16/18639 0.0625 0.316387153720804 0.970483733070805 1 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/3682 16/18639 0.0625 0.316387153720804 0.970483733070805 1 GO:0001530 lipopolysaccharide binding 4/3682 41/18639 0.0975609756097561 0.493872630198328 0.973612795618029 1 GO:0140318 protein transporter activity 4/3682 41/18639 0.0975609756097561 0.493872630198328 0.973612795618029 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 18/3682 132/18639 0.136363636363636 0.690299244481754 0.97435544884767 1 GO:0001637 G protein-coupled chemoattractant receptor activity 2/3682 26/18639 0.0769230769230769 0.38939957381022 0.97584587417522 1 GO:0004950 chemokine receptor activity 2/3682 26/18639 0.0769230769230769 0.38939957381022 0.97584587417522 1 GO:0015145 monosaccharide transmembrane transporter activity 2/3682 26/18639 0.0769230769230769 0.38939957381022 0.97584587417522 1 GO:0030507 spectrin binding 2/3682 26/18639 0.0769230769230769 0.38939957381022 0.97584587417522 1 GO:0030414 peptidase inhibitor activity 24/3682 169/18639 0.142011834319527 0.718891520880407 0.976146386955916 1 GO:0009881 photoreceptor activity 1/3682 17/18639 0.0588235294117647 0.297776144678404 0.976319468174349 1 GO:0045236 CXCR chemokine receptor binding 1/3682 17/18639 0.0588235294117647 0.297776144678404 0.976319468174349 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 26/3682 181/18639 0.143646408839779 0.727166054960522 0.976335883063267 1 GO:0046873 metal ion transmembrane transporter activity 73/3682 450/18639 0.162222222222222 0.821200434546442 0.977331742660757 1 GO:0042056 chemoattractant activity 4/3682 42/18639 0.0952380952380952 0.482113758050749 0.977391757954122 1 GO:0016782 transferase activity, transferring sulphur-containing groups 8/3682 70/18639 0.114285714285714 0.578536509660899 0.977721817070701 1 GO:0016887 ATP hydrolysis activity 67/3682 417/18639 0.160671462829736 0.813350188941731 0.977975376165798 1 GO:0004623 phospholipase A2 activity 3/3682 35/18639 0.0857142857142857 0.433902382245674 0.979457938928545 1 GO:0005104 fibroblast growth factor receptor binding 2/3682 27/18639 0.0740740740740741 0.374977367372805 0.979978171219657 1 GO:0004970 glutamate-gated receptor activity 1/3682 18/18639 0.0555555555555556 0.281233025529603 0.98100165688566 1 GO:0005372 water transmembrane transporter activity 1/3682 18/18639 0.0555555555555556 0.281233025529603 0.98100165688566 1 GO:0030544 Hsp70 protein binding 5/3682 51/18639 0.0980392156862745 0.496293574464006 0.98249974221441 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/3682 36/18639 0.0833333333333333 0.421849538294405 0.982667274051155 1 GO:0005242 inward rectifier potassium channel activity 2/3682 28/18639 0.0714285714285714 0.361585318538062 0.983420932311806 1 GO:0051119 sugar transmembrane transporter activity 2/3682 28/18639 0.0714285714285714 0.361585318538062 0.983420932311806 1 GO:0022840 leak channel activity 1/3682 19/18639 0.0526315789473684 0.266431287343835 0.984758270351479 1 GO:0022842 narrow pore channel activity 1/3682 19/18639 0.0526315789473684 0.266431287343835 0.984758270351479 1 GO:0030506 ankyrin binding 1/3682 19/18639 0.0526315789473684 0.266431287343835 0.984758270351479 1 GO:0004497 monooxygenase activity 13/3682 106/18639 0.122641509433962 0.620835169565351 0.984863812402325 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/3682 20/18639 0.05 0.253109722976643 0.98777223643987 1 GO:0015464 acetylcholine receptor activity 1/3682 20/18639 0.05 0.253109722976643 0.98777223643987 1 GO:0140664 ATP-dependent DNA damage sensor activity 1/3682 20/18639 0.05 0.253109722976643 0.98777223643987 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 4/3682 46/18639 0.0869565217391304 0.440190822568075 0.98797918131181 1 GO:0098918 structural constituent of synapse 2/3682 30/18639 0.0666666666666667 0.337479630635524 0.988665226800591 1 GO:0099095 ligand-gated monoatomic anion channel activity 4/3682 47/18639 0.0851063829787234 0.430825060385776 0.989766959613782 1 GO:0051428 peptide hormone receptor binding 1/3682 21/18639 0.0476190476190476 0.241056879025374 0.99019033759613 1 GO:0061891 calcium ion sensor activity 1/3682 21/18639 0.0476190476190476 0.241056879025374 0.99019033759613 1 GO:0005125 cytokine activity 33/3682 234/18639 0.141025641025641 0.71389921865207 0.990553584894494 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/3682 31/18639 0.0645161290322581 0.326593190937604 0.990640397706518 1 GO:0015144 carbohydrate transmembrane transporter activity 3/3682 40/18639 0.075 0.379664584464965 0.991318318579686 1 GO:0004175 endopeptidase activity 62/3682 405/18639 0.153086419753086 0.774953225903796 0.991727504559076 1 GO:0004812 aminoacyl-tRNA ligase activity 3/3682 41/18639 0.0731707317073171 0.370404472648746 0.992716123024028 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/3682 41/18639 0.0731707317073171 0.370404472648746 0.992716123024028 1 GO:0016835 carbon-oxygen lyase activity 8/3682 79/18639 0.10126582278481 0.512627287041303 0.99311264662933 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/3682 23/18639 0.0434782608695652 0.220095411284037 0.993686780799023 1 GO:0008201 heparin binding 22/3682 172/18639 0.127906976744186 0.647489989010017 0.994016442042798 1 GO:0015079 potassium ion transmembrane transporter activity 20/3682 160/18639 0.125 0.632774307441608 0.994360517414008 1 GO:0015149 hexose transmembrane transporter activity 1/3682 24/18639 0.0416666666666667 0.210924769147203 0.994935452538279 1 GO:0015295 solute:proton symporter activity 1/3682 24/18639 0.0416666666666667 0.210924769147203 0.994935452538279 1 GO:0055056 D-glucose transmembrane transporter activity 1/3682 24/18639 0.0416666666666667 0.210924769147203 0.994935452538279 1 GO:0003777 microtubule motor activity 6/3682 68/18639 0.0882352941176471 0.446664217017606 0.995833325703439 1 GO:0005251 delayed rectifier potassium channel activity 1/3682 25/18639 0.04 0.202487778381315 0.995937207239008 1 GO:0015271 outward rectifier potassium channel activity 1/3682 25/18639 0.04 0.202487778381315 0.995937207239008 1 GO:0003724 RNA helicase activity 7/3682 77/18639 0.0909090909090909 0.460199496321169 0.996689150755356 1 GO:0004435 phosphatidylinositol phospholipase C activity 1/3682 26/18639 0.0384615384615385 0.19469978690511 0.996740860561559 1 GO:0050681 nuclear androgen receptor binding 1/3682 26/18639 0.0384615384615385 0.19469978690511 0.996740860561559 1 GO:0008094 ATP-dependent activity, acting on DNA 27/3682 210/18639 0.128571428571429 0.650853573368511 0.996880726645415 1 GO:0008186 ATP-dependent activity, acting on RNA 7/3682 79/18639 0.0886075949367089 0.44854887616114 0.99753131125686 1 GO:0004620 phospholipase activity 11/3682 109/18639 0.100917431192661 0.510863661053775 0.997897882980778 1 GO:0016298 lipase activity 14/3682 130/18639 0.107692307692308 0.545159403334308 0.997983403665653 1 GO:0005262 calcium channel activity 14/3682 131/18639 0.106870229007634 0.540997881171451 0.998215043447029 1 GO:0004629 phospholipase C activity 1/3682 29/18639 0.0344827586206897 0.174558429639064 0.998317700822718 1 GO:0140097 catalytic activity, acting on DNA 46/3682 336/18639 0.136904761904762 0.693038527197951 0.998667247642731 1 GO:0015085 calcium ion transmembrane transporter activity 16/3682 147/18639 0.108843537414966 0.550987152057999 0.998671452684539 1 GO:0008227 G protein-coupled amine receptor activity 2/3682 41/18639 0.0487804878048781 0.246936315099164 0.998673534010025 1 GO:0004386 helicase activity 17/3682 155/18639 0.109677419354839 0.555208424593927 0.998856734503584 1 GO:0005184 neuropeptide hormone activity 1/3682 31/18639 0.032258064516129 0.163296595468802 0.998917549656116 1 GO:0016836 hydro-lyase activity 4/3682 61/18639 0.0655737704918033 0.331947177674286 0.999032294731862 1 GO:0005216 monoatomic ion channel activity 64/3682 448/18639 0.142857142857143 0.723170637076123 0.99906718482213 1 GO:0160041 neuropeptide activity 1/3682 32/18639 0.03125 0.158193576860402 0.99913173614398 1 GO:0005267 potassium channel activity 12/3682 124/18639 0.0967741935483871 0.489889786406406 0.999262661634726 1 GO:0019825 oxygen binding 1/3682 34/18639 0.0294117647058824 0.148888072339202 0.999441372992248 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 3/3682 56/18639 0.0535714285714286 0.271188988903546 0.999526323546033 1 GO:0003730 mRNA 3'-UTR binding 32/3682 262/18639 0.122137404580153 0.618283292767372 0.999578642282538 1 GO:0099094 ligand-gated monoatomic cation channel activity 13/3682 136/18639 0.0955882352941176 0.483886235102406 0.999614642089327 1 GO:0008528 G protein-coupled peptide receptor activity 11/3682 122/18639 0.0901639344262295 0.456427369302143 0.999639188181048 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/3682 36/18639 0.0277777777777778 0.140616512764802 0.999640607426985 1 GO:0030280 structural constituent of skin epidermis 1/3682 37/18639 0.027027027027027 0.136816066473861 0.999711740225665 1 GO:0005179 hormone activity 12/3682 132/18639 0.0909090909090909 0.460199496321169 0.999751443525776 1 GO:0098960 postsynaptic neurotransmitter receptor activity 4/3682 69/18639 0.0579710144927536 0.293460548378717 0.999765177570011 1 GO:0001653 peptide receptor activity 11/3682 128/18639 0.0859375 0.435032336366105 0.99984610291948 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/3682 53/18639 0.0377358490566038 0.191026206020108 0.999881031516203 1 GO:0005261 monoatomic cation channel activity 41/3682 341/18639 0.120234604105572 0.608650946747353 0.999951564186841 1 GO:0003823 antigen binding 16/3682 174/18639 0.0919540229885057 0.465489145704171 0.999957380475068 1 GO:0017171 serine hydrolase activity 19/3682 198/18639 0.095959595959596 0.485766135005679 0.999969380550787 1 GO:0008188 neuropeptide receptor activity 1/3682 48/18639 0.0208333333333333 0.105462384573601 0.999974545296839 1 GO:0008236 serine-type peptidase activity 18/3682 194/18639 0.0927835051546392 0.469688145729853 0.999979764176234 1 GO:0022824 transmitter-gated monoatomic ion channel activity 2/3682 63/18639 0.0317460317460317 0.160704586016916 0.999984626939032 1 GO:0022835 transmitter-gated channel activity 2/3682 63/18639 0.0317460317460317 0.160704586016916 0.999984626939032 1 GO:0015276 ligand-gated monoatomic ion channel activity 16/3682 186/18639 0.0860215053763441 0.435457587916805 0.999991842739577 1 GO:0005249 voltage-gated potassium channel activity 5/3682 98/18639 0.0510204081632653 0.258275227527187 0.999993454684748 1 GO:0022834 ligand-gated channel activity 16/3682 188/18639 0.0851063829787234 0.430825060385776 0.99999384714611 1 GO:0004252 serine-type endopeptidase activity 14/3682 176/18639 0.0795454545454545 0.402674559281023 0.999996103778152 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/3682 73/18639 0.0273972602739726 0.138690259165284 0.999998060250006 1 GO:0005244 voltage-gated monoatomic ion channel activity 13/3682 173/18639 0.0751445086705202 0.380396115456227 0.999998099356921 1 GO:0022832 voltage-gated channel activity 13/3682 175/18639 0.0742857142857143 0.376048731279584 0.999998599578821 1 GO:0030594 neurotransmitter receptor activity 4/3682 97/18639 0.0412371134020619 0.208750286991046 0.999998715276856 1 GO:0022836 gated channel activity 30/3682 318/18639 0.0943396226415094 0.47756551505027 0.999999862883774 1 GO:0022843 voltage-gated monoatomic cation channel activity 6/3682 143/18639 0.041958041958042 0.212399767532847 0.999999990414266 1 GO:0030527 structural constituent of chromatin 1/3682 98/18639 0.0102040816326531 0.0516550455054374 0.999999999596378 1 GO:0004984 olfactory receptor activity 1/3682 419/18639 0.00238663484486874 0.0120816096886226 1 1 GO:0030371 translation repressor activity 9/3682 329/18639 0.027355623100304 0.138479483695428 1 1 GO:0045182 translation regulator activity 11/3682 356/18639 0.0308988764044944 0.156416120940622 1 1