ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0140297	DNA-binding transcription factor binding	136/2503	488/18639	0.278688524590164	2.07529980416942	1.21188252821853e-17	1.57544728668409e-14
GO:0003712	transcription coregulator activity	134/2503	495/18639	0.270707070707071	2.01586459884502	2.82333634328044e-16	1.83516862313229e-13
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	100/2503	349/18639	0.286532951289398	2.13371461409632	3.93190905804266e-14	1.70382725848515e-11
GO:0003713	transcription coactivator activity	77/2503	256/18639	0.30078125	2.23981690721135	2.38432758003216e-12	7.74906463510451e-10
GO:0042393	histone binding	71/2503	247/18639	0.287449392712551	2.14053904545315	1.66931528369373e-10	4.3402197376037e-08
GO:0045296	cadherin binding	87/2503	334/18639	0.260479041916168	1.93969990502415	4.23441822758544e-10	9.17457282643511e-08
GO:0031491	nucleosome binding	31/2503	74/18639	0.418918918918919	3.11954843377137	1.43285817502314e-09	2.66102232504298e-07
GO:0031267	small GTPase binding	75/2503	283/18639	0.265017667844523	1.97349752734881	2.96411567959859e-09	4.81668797934771e-07
GO:0030695	GTPase regulator activity	112/2503	489/18639	0.229038854805726	1.70557539541507	5.36905814522967e-09	7.75530620977619e-07
GO:0060589	nucleoside-triphosphatase regulator activity	112/2503	490/18639	0.228571428571429	1.70209462930198	6.05918799166758e-09	7.87694438916786e-07
GO:0051020	GTPase binding	80/2503	315/18639	0.253968253968254	1.89121625477998	7.38071688674003e-09	8.72266541160185e-07
GO:0046332	SMAD binding	31/2503	79/18639	0.392405063291139	2.92210865948204	9.51026208784189e-09	1.03027839284954e-06
GO:0140030	modification-dependent protein binding	51/2503	173/18639	0.294797687861272	2.19525933042199	2.43949881960247e-08	2.43949881960247e-06
GO:0003714	transcription corepressor activity	57/2503	204/18639	0.279411764705882	2.08068553030481	3.11982721031001e-08	2.89698240957358e-06
GO:0031490	chromatin DNA binding	40/2503	128/18639	0.3125	2.3270825009988	1.37157666021554e-07	1.1886997721868e-05
GO:0003779	actin binding	98/2503	443/18639	0.221218961625282	1.64734327835942	2.79778594115252e-07	2.27320107718642e-05
GO:0005096	GTPase activator activity	67/2503	271/18639	0.247232472324723	1.84105715208171	3.51167477313612e-07	2.68539835592762e-05
GO:0034212	protein N-acetyltransferase activity	22/2503	53/18639	0.415094339622642	3.09106807679841	4.15905545773878e-07	3.00376227503357e-05
GO:0004402	histone acetyltransferase activity	19/2503	42/18639	0.452380952380952	3.36872895382684	5.11647775041474e-07	3.50074793449429e-05
GO:0001221	transcription coregulator binding	36/2503	115/18639	0.31304347826087	2.33112960100054	5.43113943832952e-07	3.53024063491419e-05
GO:0061733	protein-lysine-acetyltransferase activity	20/2503	47/18639	0.425531914893617	3.16879319284943	8.62989945911651e-07	5.34231871278641e-05
GO:0016922	nuclear receptor binding	40/2503	137/18639	0.291970802919708	2.17420846808647	9.99093808610407e-07	5.90373614178877e-05
GO:0140033	acetylation-dependent protein binding	13/2503	24/18639	0.541666666666667	4.03360966839792	2.62575527669745e-06	0.000148412254769856
GO:0035091	phosphatidylinositol binding	66/2503	284/18639	0.232394366197183	1.73056276130615	4.29362638757425e-06	0.000232571429326938
GO:0008080	N-acetyltransferase activity	24/2503	69/18639	0.347826086956522	2.59014400111171	5.4328220625885e-06	0.000282506747254602
GO:0001046	core promoter sequence-specific DNA binding	18/2503	44/18639	0.409090909090909	3.04636254676207	5.97297134794022e-06	0.000287897392518369
GO:0005543	phospholipid binding	102/2503	497/18639	0.20523138832998	1.52828919180283	5.97940738307382e-06	0.000287897392518369
GO:0044013	histone H2B acetyltransferase activity	12/2503	23/18639	0.521739130434783	3.88521600166756	1.07377480578561e-05	0.00048134732673148
GO:0070577	lysine-acetylated histone binding	12/2503	23/18639	0.521739130434783	3.88521600166756	1.07377480578561e-05	0.00048134732673148
GO:0048407	platelet-derived growth factor binding	8/2503	11/18639	0.727272727272727	5.41575563868812	1.18234260261746e-05	0.000512348461134234
GO:0010485	histone H4 acetyltransferase activity	15/2503	35/18639	0.428571428571429	3.19142742994121	1.82315682607347e-05	0.000741905199709795
GO:0042826	histone deacetylase binding	35/2503	127/18639	0.275590551181102	2.05223023710131	1.86436489517545e-05	0.000741905199709795
GO:0002039	p53 binding	23/2503	69/18639	0.333333333333333	2.48222133439872	1.88329781464794e-05	0.000741905199709795
GO:0036408	histone H3K14 acetyltransferase activity	13/2503	28/18639	0.464285714285714	3.45737971576965	2.33026973800332e-05	0.000890985488060094
GO:0004386	helicase activity	40/2503	155/18639	0.258064516129032	1.9217197427603	2.66453374526985e-05	0.000989683962528802
GO:0019838	growth factor binding	36/2503	136/18639	0.264705882352941	1.97117576555193	3.68869188743857e-05	0.00110122087262491
GO:0010484	histone H3 acetyltransferase activity	13/2503	29/18639	0.448275862068966	3.33815972557069	3.70536079925614e-05	0.00110122087262491
GO:0004674	protein serine/threonine kinase activity	88/2503	433/18639	0.203233256351039	1.51340977432162	3.71544236338997e-05	0.00110122087262491
GO:0032931	histone H3K56 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0043992	histone H3K9 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0043993	histone H3K18 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0043994	histone H3K23 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0043999	histone H2AK5 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0044012	histone H2AK9 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0044014	histone H2BK5 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0044015	histone H2BK12 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0044016	histone H3K4 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0044017	histone H3K27 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0044018	histone H3K36 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0140908	histone H3K122 acetyltransferase activity	11/2503	22/18639	0.5	3.72333200159808	4.23546489471119e-05	0.00110122087262491
GO:0070063	RNA polymerase binding	20/2503	59/18639	0.338983050847458	2.52429288243938	4.93931792919837e-05	0.00125904182508978
GO:0031492	nucleosomal DNA binding	16/2503	42/18639	0.380952380952381	2.83682438216997	5.56798507132223e-05	0.0013442735301377
GO:0043995	histone H4K5 acetyltransferase activity	13/2503	30/18639	0.433333333333333	3.22688773471834	5.73724615284361e-05	0.0013442735301377
GO:0043996	histone H4K8 acetyltransferase activity	13/2503	30/18639	0.433333333333333	3.22688773471834	5.73724615284361e-05	0.0013442735301377
GO:0043997	histone H4K12 acetyltransferase activity	13/2503	30/18639	0.433333333333333	3.22688773471834	5.73724615284361e-05	0.0013442735301377
GO:0008135	translation factor activity, RNA binding	25/2503	83/18639	0.301204819277108	2.24297108530005	5.79071674520856e-05	0.0013442735301377
GO:0180051	translation factor activity	25/2503	84/18639	0.297619047619048	2.21626904857029	7.20446147308453e-05	0.001643122792107
GO:0032266	phosphatidylinositol-3-phosphate binding	17/2503	48/18639	0.354166666666667	2.63736016779864	9.61821692956866e-05	0.00215580724283436
GO:0051015	actin filament binding	48/2503	209/18639	0.229665071770335	1.71023862274362	0.000112080541219962	0.0024400448677763
GO:0001217	DNA-binding transcription repressor activity	60/2503	278/18639	0.215827338129496	1.60719366975457	0.000112617455435829	0.0024400448677763
GO:0043998	histone H2A acetyltransferase activity	11/2503	24/18639	0.458333333333333	3.41305433479824	0.000115748941928089	0.002466780729615
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	58/2503	268/18639	0.216417910447761	1.61159146337827	0.000134326585303322	0.00281652517571481
GO:0016410	N-acyltransferase activity	26/2503	94/18639	0.276595744680851	2.05971557535213	0.000197882497079414	0.00406302313322115
GO:0003727	single-stranded RNA binding	25/2503	89/18639	0.280898876404494	2.0917595514596	0.000200025754250887	0.00406302313322115
GO:0031625	ubiquitin protein ligase binding	63/2503	302/18639	0.208609271523179	1.55344315298463	0.000212162305363278	0.00424324610726556
GO:0070628	proteasome binding	9/2503	18/18639	0.5	3.72333200159808	0.000216244902117909	0.00425936928414062
GO:0046972	histone H4K16 acetyltransferase activity	10/2503	22/18639	0.454545454545455	3.38484727418007	0.000258784996667664	0.00489361000863009
GO:0140517	protein-RNA adaptor activity	10/2503	22/18639	0.454545454545455	3.38484727418007	0.000258784996667664	0.00489361000863009
GO:0140938	histone H3 methyltransferase activity	16/2503	47/18639	0.340425531914894	2.53503455427955	0.00025973776199652	0.00489361000863009
GO:0005160	transforming growth factor beta receptor binding	11/2503	26/18639	0.423076923076923	3.15051169365992	0.000276882723922611	0.00503565532343697
GO:0050681	nuclear androgen receptor binding	11/2503	26/18639	0.423076923076923	3.15051169365992	0.000276882723922611	0.00503565532343697
GO:0042809	nuclear vitamin D receptor binding	8/2503	15/18639	0.533333333333333	3.97155413503795	0.000278897833298048	0.00503565532343697
GO:0016407	acetyltransferase activity	26/2503	96/18639	0.270833333333333	2.01680483419896	0.000285421778088896	0.0050724657136291
GO:0005080	protein kinase C binding	17/2503	52/18639	0.326923076923077	2.43448630873721	0.000292877287995303	0.0050724657136291
GO:0098631	cell adhesion mediator activity	22/2503	76/18639	0.289473684210526	2.1556132640831	0.00029652204093191	0.0050724657136291
GO:0048156	tau protein binding	15/2503	43/18639	0.348837209302326	2.59767348948703	0.000296544149412163	0.0050724657136291
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	92/2503	484/18639	0.190082644628099	1.41548158738439	0.000308248417905125	0.00520419406852808
GO:0005201	extracellular matrix structural constituent	39/2503	168/18639	0.232142857142857	1.72868985788482	0.000373907358338339	0.0062015311014982
GO:1901981	phosphatidylinositol phosphate binding	42/2503	185/18639	0.227027027027027	1.69059398991481	0.000376862274629506	0.0062015311014982
GO:0030020	extracellular matrix structural constituent conferring tensile strength	15/2503	44/18639	0.340909090909091	2.53863545563506	0.000394599171147873	0.00638864249073208
GO:0042171	lysophosphatidic acid acyltransferase activity	10/2503	23/18639	0.434782608695652	3.23768000138964	0.00040297591095387	0.00638864249073208
GO:0071617	lysophospholipid acyltransferase activity	10/2503	23/18639	0.434782608695652	3.23768000138964	0.00040297591095387	0.00638864249073208
GO:1990841	promoter-specific chromatin binding	20/2503	68/18639	0.294117647058824	2.1901952950577	0.000436868320089173	0.00682822419385481
GO:0044389	ubiquitin-like protein ligase binding	65/2503	322/18639	0.201863354037267	1.50320857207376	0.000441208332526003	0.00682822419385481
GO:0005024	transforming growth factor beta receptor activity	8/2503	16/18639	0.5	3.72333200159808	0.000492212469396391	0.00752795541429774
GO:0001216	DNA-binding transcription activator activity	92/2503	491/18639	0.187372708757637	1.39530160548686	0.000505704120748028	0.00764436461595857
GO:0046966	nuclear thyroid hormone receptor binding	11/2503	28/18639	0.392857142857143	2.92547514411278	0.000595152070087425	0.00889307690935232
GO:0070123	transforming growth factor beta receptor activity, type III	7/2503	13/18639	0.538461538461538	4.00974215556717	0.000637655971566064	0.00913762701734376
GO:0005178	integrin binding	37/2503	161/18639	0.229813664596273	1.71134514359166	0.000638169199762348	0.00913762701734376
GO:0001098	basal transcription machinery binding	18/2503	60/18639	0.3	2.23399920095885	0.000639633891214063	0.00913762701734376
GO:0001099	basal RNA polymerase II transcription machinery binding	18/2503	60/18639	0.3	2.23399920095885	0.000639633891214063	0.00913762701734376
GO:0003743	translation initiation factor activity	16/2503	51/18639	0.313725490196078	2.33620831472821	0.000732352528722931	0.0103484596449979
GO:0008190	eukaryotic initiation factor 4E binding	6/2503	10/18639	0.6	4.4679984019177	0.000753605229009996	0.0104221999756702
GO:0042975	peroxisome proliferator activated receptor binding	6/2503	10/18639	0.6	4.4679984019177	0.000753605229009996	0.0104221999756702
GO:0019207	kinase regulator activity	58/2503	287/18639	0.202090592334495	1.50490073932187	0.000844613874422234	0.0115578740710411
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	9/2503	21/18639	0.428571428571429	3.19142742994121	0.000894806525909875	0.0121171717050296
GO:0030165	PDZ domain binding	22/2503	83/18639	0.265060240963855	1.97381455506404	0.0011085463555629	0.0148363324978115
GO:0005085	guanyl-nucleotide exchange factor activity	48/2503	230/18639	0.208695652173913	1.55408640066703	0.00111843121906579	0.0148363324978115
GO:0140296	general transcription initiation factor binding	16/2503	53/18639	0.30188679245283	2.24804951039884	0.0011654519936789	0.0153039150685108
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	8/2503	18/18639	0.444444444444444	3.30962844586496	0.00130414170998721	0.0169538422298338
GO:0008276	protein methyltransferase activity	24/2503	95/18639	0.252631578947368	1.88126248501798	0.00140000988144522	0.0178279787164171
GO:0001222	transcription corepressor binding	15/2503	49/18639	0.306122448979592	2.27959102138658	0.00140564983413996	0.0178279787164171
GO:0035064	methylated histone binding	20/2503	74/18639	0.27027027027027	2.01261189275572	0.00141252446753151	0.0178279787164171
GO:0008013	beta-catenin binding	26/2503	106/18639	0.245283018867925	1.82654022719906	0.00144137815546435	0.0180172269433044
GO:0004016	adenylate cyclase activity	6/2503	11/18639	0.545454545454545	4.06181672901609	0.0014695910257076	0.0181949365087608
GO:0051087	protein-folding chaperone binding	31/2503	134/18639	0.23134328358209	1.72273570223195	0.00150134019351568	0.018412662750664
GO:0061791	GTPase motor activity	13/2503	40/18639	0.325	2.42016580103875	0.0015703537477363	0.0189024062227517
GO:1990606	membrane scission GTPase motor activity	13/2503	40/18639	0.325	2.42016580103875	0.0015703537477363	0.0189024062227517
GO:0097110	scaffold protein binding	19/2503	70/18639	0.271428571428571	2.0212373722961	0.00174076375877107	0.0207614026275449
GO:0019787	ubiquitin-like protein transferase activity	87/2503	479/18639	0.181628392484342	1.35252561227154	0.0018575683041243	0.0219530799578327
GO:0016849	phosphorus-oxygen lyase activity	9/2503	23/18639	0.391304347826087	2.91391200125067	0.00193437047372851	0.0226547893319556
GO:0042800	histone H3K4 methyltransferase activity	8/2503	19/18639	0.421052631578947	3.13543747502996	0.00198932799228629	0.0230425248105601
GO:0140034	methylation-dependent protein binding	20/2503	76/18639	0.263157894736842	1.95964842189373	0.00200576800732414	0.0230425248105601
GO:0042169	SH2 domain binding	13/2503	41/18639	0.317073170731707	2.36113736686708	0.00202065217569527	0.0230425248105601
GO:0016755	aminoacyltransferase activity	89/2503	496/18639	0.179435483870968	1.33619575863802	0.00239059889093468	0.0266784367708137
GO:0042805	actinin binding	12/2503	37/18639	0.324324324324324	2.41513427130686	0.00240176552723865	0.0266784367708137
GO:0051393	alpha-actinin binding	10/2503	28/18639	0.357142857142857	2.65952285828434	0.0024487381594456	0.0266784367708137
GO:0003697	single-stranded DNA binding	28/2503	121/18639	0.231404958677686	1.72319497594622	0.0024619506659659	0.0266784367708137
GO:0005518	collagen binding	19/2503	72/18639	0.263888888888889	1.96509188973232	0.00247967594993157	0.0266784367708137
GO:0043175	RNA polymerase core enzyme binding	13/2503	42/18639	0.30952380952381	2.3049198105131	0.0025720457074063	0.0266784367708137
GO:0042054	histone methyltransferase activity	18/2503	67/18639	0.26865671641791	2.00059629936613	0.0025724373475278	0.0266784367708137
GO:0005025	transforming growth factor beta receptor activity, type I	6/2503	12/18639	0.5	3.72333200159808	0.00260627805376411	0.0266784367708137
GO:0005026	transforming growth factor beta receptor activity, type II	6/2503	12/18639	0.5	3.72333200159808	0.00260627805376411	0.0266784367708137
GO:0016361	activin receptor activity, type I	6/2503	12/18639	0.5	3.72333200159808	0.00260627805376411	0.0266784367708137
GO:0016362	activin receptor activity, type II	6/2503	12/18639	0.5	3.72333200159808	0.00260627805376411	0.0266784367708137
GO:0017002	activin receptor activity	6/2503	12/18639	0.5	3.72333200159808	0.00260627805376411	0.0266784367708137
GO:1990247	N6-methyladenosine-containing RNA reader activity	6/2503	12/18639	0.5	3.72333200159808	0.00260627805376411	0.0266784367708137
GO:0048027	mRNA 5'-UTR binding	9/2503	24/18639	0.375	2.79249900119856	0.00273010993895367	0.0277276790674982
GO:0008094	ATP-dependent activity, acting on DNA	43/2503	210/18639	0.204761904761905	1.52479310541636	0.00286012613036635	0.0288229765075679
GO:0106222	lncRNA binding	10/2503	29/18639	0.344827586206897	2.56781517351592	0.00329362900182447	0.0326118684952495
GO:0140658	ATP-dependent chromatin remodeler activity	34/2503	158/18639	0.215189873417722	1.60244668423209	0.00330089292002295	0.0326118684952495
GO:0051018	protein kinase A binding	15/2503	53/18639	0.283018867924528	2.10754641599891	0.00331135895490226	0.0326118684952495
GO:0019887	protein kinase regulator activity	50/2503	255/18639	0.196078431372549	1.46013019670513	0.00352120915731288	0.0344178338684718
GO:0016279	protein-lysine N-methyltransferase activity	18/2503	69/18639	0.260869565217391	1.94260800083378	0.00363932278944749	0.0353068628826995
GO:0042974	nuclear retinoic acid receptor binding	9/2503	25/18639	0.36	2.68079904115062	0.0037638017938203	0.0362440172738251
GO:0031593	polyubiquitin modification-dependent protein binding	16/2503	59/18639	0.271186440677966	2.0194343059515	0.00393027516293438	0.0375688067045198
GO:0001223	transcription coactivator binding	13/2503	44/18639	0.295454545454545	2.20015072821705	0.00404386163015619	0.0383724096292193
GO:0031072	heat shock protein binding	29/2503	131/18639	0.221374045801527	1.64849813811213	0.00414869242653139	0.0388193785143919
GO:0009975	cyclase activity	8/2503	21/18639	0.380952380952381	2.83682438216997	0.00418054845539605	0.0388193785143919
GO:0010314	phosphatidylinositol-5-phosphate binding	8/2503	21/18639	0.380952380952381	2.83682438216997	0.00418054845539605	0.0388193785143919
GO:0097157	pre-mRNA intronic binding	6/2503	13/18639	0.461538461538462	3.436921847629	0.00429366840993388	0.0393343041555361
GO:0016278	lysine N-methyltransferase activity	18/2503	70/18639	0.257142857142857	1.91485645796473	0.00429651630006625	0.0393343041555361
GO:0035925	mRNA 3'-UTR AU-rich region binding	10/2503	30/18639	0.333333333333333	2.48222133439872	0.00435460714661757	0.0395873376965233
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	16/2503	60/18639	0.266666666666667	1.98577706751898	0.00470455468515838	0.0424716742410132
GO:0004177	aminopeptidase activity	12/2503	40/18639	0.3	2.23399920095885	0.00493249765042959	0.0442223927279894
GO:0034237	protein kinase A regulatory subunit binding	9/2503	26/18639	0.346153846153846	2.57769138572175	0.0050802613135722	0.0452352034770127
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	45/2503	229/18639	0.196506550218341	1.46331825390318	0.00519979254401332	0.045984559913043
GO:0106310	protein serine kinase activity	66/2503	361/18639	0.182825484764543	1.36143995626301	0.00525424813110169	0.0461521795299473
GO:0004721	phosphoprotein phosphatase activity	36/2503	175/18639	0.205714285714286	1.53188516637178	0.00553319177576687	0.0482761698556841
GO:0016411	acylglycerol O-acyltransferase activity	10/2503	31/18639	0.32258064516129	2.40214967845038	0.00566723803808217	0.0487907910563366
GO:0070273	phosphatidylinositol-4-phosphate binding	10/2503	31/18639	0.32258064516129	2.40214967845038	0.00566723803808217	0.0487907910563366
GO:1902936	phosphatidylinositol bisphosphate binding	25/2503	111/18639	0.225225225225225	1.67717657729643	0.00589112978646625	0.0498179344717805
GO:0000993	RNA polymerase II complex binding	11/2503	36/18639	0.305555555555556	2.27536955653216	0.005999917357932	0.0498179344717805
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	5/2503	10/18639	0.5	3.72333200159808	0.00609311660077931	0.0498179344717805
GO:0003680	minor groove of adenine-thymine-rich DNA binding	5/2503	10/18639	0.5	3.72333200159808	0.00609311660077931	0.0498179344717805
GO:0051880	G-quadruplex DNA binding	5/2503	10/18639	0.5	3.72333200159808	0.00609311660077931	0.0498179344717805
GO:0099122	RNA polymerase II C-terminal domain binding	5/2503	10/18639	0.5	3.72333200159808	0.00609311660077931	0.0498179344717805
GO:0140999	histone H3K4 trimethyltransferase activity	5/2503	10/18639	0.5	3.72333200159808	0.00609311660077931	0.0498179344717805
GO:1905394	retromer complex binding	5/2503	10/18639	0.5	3.72333200159808	0.00609311660077931	0.0498179344717805
GO:0003746	translation elongation factor activity	7/2503	18/18639	0.388888888888889	2.89592489013184	0.00641586196747567	0.0521288784857398
GO:0042813	Wnt receptor activity	6/2503	14/18639	0.428571428571429	3.19142742994121	0.00666808419774799	0.0533239422473781
GO:0098821	BMP receptor activity	6/2503	14/18639	0.428571428571429	3.19142742994121	0.00666808419774799	0.0533239422473781
GO:0004842	ubiquitin-protein transferase activity	79/2503	449/18639	0.175946547884187	1.31021482461581	0.00671177255353217	0.0533239422473781
GO:0005044	scavenger receptor activity	9/2503	27/18639	0.333333333333333	2.48222133439872	0.00672702040659232	0.0533239422473781
GO:0031369	translation initiation factor binding	10/2503	32/18639	0.3125	2.3270825009988	0.00726905263223159	0.0572713237690974
GO:0043495	protein-membrane adaptor activity	13/2503	47/18639	0.276595744680851	2.05971557535213	0.00745383267394959	0.0583733884104486
GO:0005158	insulin receptor binding	8/2503	23/18639	0.347826086956522	2.59014400111171	0.00787163936536445	0.0609114950891297
GO:0008171	O-methyltransferase activity	8/2503	23/18639	0.347826086956522	2.59014400111171	0.00787163936536445	0.0609114950891297
GO:0032182	ubiquitin-like protein binding	26/2503	120/18639	0.216666666666667	1.61344386735917	0.00854024544184048	0.0656941957064652
GO:0019789	SUMO transferase activity	9/2503	28/18639	0.321428571428571	2.39357057245591	0.00875357515524077	0.0669391041283118
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	13/2503	48/18639	0.270833333333333	2.01680483419896	0.00899334406514979	0.0683704519572791
GO:0003725	double-stranded RNA binding	18/2503	75/18639	0.24	1.78719936076708	0.009204250109774	0.0695670066436407
GO:0140104	molecular carrier activity	47/2503	249/18639	0.188755020080321	1.4055952134547	0.009359653083884	0.0703326532314983
GO:0036002	pre-mRNA binding	15/2503	59/18639	0.254237288135593	1.89321966182953	0.00971247513195436	0.0718326164111524
GO:0051371	muscle alpha-actinin binding	6/2503	15/18639	0.4	2.97866560127847	0.00986643819961003	0.0718326164111524
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/2503	11/18639	0.454545454545455	3.38484727418007	0.00994605458000571	0.0718326164111524
GO:0005114	type II transforming growth factor beta receptor binding	5/2503	11/18639	0.454545454545455	3.38484727418007	0.00994605458000571	0.0718326164111524
GO:0048185	activin binding	5/2503	11/18639	0.454545454545455	3.38484727418007	0.00994605458000571	0.0718326164111524
GO:0097493	structural molecule activity conferring elasticity	5/2503	11/18639	0.454545454545455	3.38484727418007	0.00994605458000571	0.0718326164111524
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/2503	11/18639	0.454545454545455	3.38484727418007	0.00994605458000571	0.0718326164111524
GO:0003925	G protein activity	14/2503	54/18639	0.259259259259259	1.93061659342123	0.0102675560149425	0.0733396858210179
GO:0140463	chromatin-protein adaptor activity	14/2503	54/18639	0.259259259259259	1.93061659342123	0.0102675560149425	0.0733396858210179
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/2503	24/18639	0.333333333333333	2.48222133439872	0.0104424040785698	0.0737778549029389
GO:0050431	transforming growth factor beta binding	8/2503	24/18639	0.333333333333333	2.48222133439872	0.0104424040785698	0.0737778549029389
GO:0038024	cargo receptor activity	16/2503	65/18639	0.246153846153846	1.83302498540213	0.0106420974700707	0.0747823065464431
GO:0030332	cyclin binding	10/2503	34/18639	0.294117647058824	2.1901952950577	0.0114972689619635	0.0803572561857661
GO:0061775	cohesin loader activity	31/2503	153/18639	0.202614379084967	1.50880120326197	0.0118204100147091	0.0821739733642876
GO:0098632	cell-cell adhesion mediator activity	14/2503	55/18639	0.254545454545455	1.89551447354084	0.0121133232131293	0.0837623413673837
GO:0140097	catalytic activity, acting on DNA	60/2503	336/18639	0.178571428571429	1.32976142914217	0.0122387397623324	0.084181807889059
GO:0002020	protease binding	28/2503	136/18639	0.205882352941176	1.53313670654039	0.0130981576387448	0.0896189733177276
GO:0005521	lamin binding	6/2503	16/18639	0.375	2.79249900119856	0.0140207435304758	0.0948116304446296
GO:0070411	I-SMAD binding	6/2503	16/18639	0.375	2.79249900119856	0.0140207435304758	0.0948116304446296
GO:0032452	histone demethylase activity	9/2503	30/18639	0.3	2.23399920095885	0.0141488125432755	0.0948116304446296
GO:0051721	protein phosphatase 2A binding	9/2503	30/18639	0.3	2.23399920095885	0.0141488125432755	0.0948116304446296
GO:0005048	signal sequence binding	13/2503	51/18639	0.254901960784314	1.89816925571667	0.015133572253063	0.099223003660174
GO:0031543	peptidyl-proline dioxygenase activity	5/2503	12/18639	0.416666666666667	3.1027766679984	0.0151887520987497	0.099223003660174
GO:0034452	dynactin binding	5/2503	12/18639	0.416666666666667	3.1027766679984	0.0151887520987497	0.099223003660174
GO:0070410	co-SMAD binding	5/2503	12/18639	0.416666666666667	3.1027766679984	0.0151887520987497	0.099223003660174
GO:0141221	histone deacetylase activity, hydrolytic mechanism	5/2503	12/18639	0.416666666666667	3.1027766679984	0.0151887520987497	0.099223003660174
GO:0008186	ATP-dependent activity, acting on RNA	18/2503	79/18639	0.227848101265823	1.6967082538928	0.0157332410122186	0.102266066579421
GO:0030276	clathrin binding	12/2503	46/18639	0.260869565217391	1.94260800083378	0.0160105163307036	0.103550603133904
GO:0140597	protein carrier chaperone	36/2503	188/18639	0.191489361702128	1.42595693678224	0.0169269025116401	0.107616859613894
GO:0000510	H3-H4 histone complex chaperone activity	30/2503	151/18639	0.198675496688742	1.47946966950917	0.0170531331388171	0.107616859613894
GO:0140584	chromatin extrusion motor activity	30/2503	151/18639	0.198675496688742	1.47946966950917	0.0170531331388171	0.107616859613894
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	30/2503	151/18639	0.198675496688742	1.47946966950917	0.0170531331388171	0.107616859613894
GO:0140849	ATP-dependent H2AZ histone chaperone activity	30/2503	151/18639	0.198675496688742	1.47946966950917	0.0170531331388171	0.107616859613894
GO:0048029	monosaccharide binding	17/2503	74/18639	0.22972972972973	1.71072010884236	0.0171766860895198	0.107872907808578
GO:0070006	metalloaminopeptidase activity	8/2503	26/18639	0.307692307692308	2.29128123175267	0.0173652821546077	0.108533013466298
GO:0140457	protein demethylase activity	9/2503	31/18639	0.290322580645161	2.16193471060534	0.0176185475681273	0.109589051859165
GO:0140713	histone chaperone activity	32/2503	164/18639	0.195121951219512	1.45300761037974	0.0181007622072814	0.112052337473647
GO:0004677	DNA-dependent protein kinase activity	45/2503	246/18639	0.182926829268293	1.36219463473101	0.0183787805831704	0.113234193166453
GO:0015616	DNA translocase activity	30/2503	152/18639	0.197368421052632	1.4697363164203	0.0185972101691309	0.113504099623804
GO:0140674	ATP-dependent histone chaperone activity	30/2503	152/18639	0.197368421052632	1.4697363164203	0.0185972101691309	0.113504099623804
GO:0008170	N-methyltransferase activity	21/2503	98/18639	0.214285714285714	1.59571371497061	0.0190096926665457	0.115341541736456
GO:0061980	regulatory RNA binding	14/2503	58/18639	0.241379310344828	1.79747062146114	0.0192167170405695	0.115341541736456
GO:0015278	intracellularly gated calcium channel activity	6/2503	17/18639	0.352941176470588	2.62823435406923	0.0192531650437007	0.115341541736456
GO:0032183	SUMO binding	6/2503	17/18639	0.352941176470588	2.62823435406923	0.0192531650437007	0.115341541736456
GO:0035402	histone H3T11 kinase activity	45/2503	247/18639	0.182186234817814	1.35667967669566	0.0196346071790818	0.117087107031221
GO:0048487	beta-tubulin binding	11/2503	42/18639	0.261904761904762	1.95031676274185	0.020051453016453	0.119026890052004
GO:0051219	phosphoprotein binding	20/2503	93/18639	0.21505376344086	1.60143311896692	0.0209356440288292	0.123710623806718
GO:0003689	DNA clamp loader activity	31/2503	160/18639	0.19375	1.44279115061926	0.0216682342483314	0.127460201460773
GO:0046975	histone H3K36 methyltransferase activity	5/2503	13/18639	0.384615384615385	2.86410153969083	0.0219981794042596	0.12766800547115
GO:0051011	microtubule minus-end binding	5/2503	13/18639	0.384615384615385	2.86410153969083	0.0219981794042596	0.12766800547115
GO:0140852	histone ubiquitin ligase activity	5/2503	13/18639	0.384615384615385	2.86410153969083	0.0219981794042596	0.12766800547115
GO:0001786	phosphatidylserine binding	14/2503	59/18639	0.23728813559322	1.76700501770756	0.0221735923010275	0.12805115370439
GO:0036121	double-stranded DNA helicase activity	12/2503	48/18639	0.25	1.86166600079904	0.022261200567071	0.12805115370439
GO:0140789	histone phosphatase activity	27/2503	136/18639	0.198529411764706	1.47838182416394	0.0229179606693822	0.130924729560957
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	44/2503	243/18639	0.181069958847737	1.34836714461165	0.0229725997252749	0.130924729560957
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	32/2503	167/18639	0.191616766467066	1.42690567725915	0.0230628946688148	0.130924729560957
GO:0004712	protein serine/threonine/tyrosine kinase activity	11/2503	43/18639	0.255813953488372	1.90496055895716	0.023768947972239	0.132498824857068
GO:0017069	snRNA binding	13/2503	54/18639	0.240740740740741	1.79271540817685	0.0240440955243009	0.132498824857068
GO:0003724	RNA helicase activity	17/2503	77/18639	0.220779220779221	1.64406867603032	0.0249083754025828	0.132498824857068
GO:0005109	frizzled binding	10/2503	38/18639	0.263157894736842	1.95964842189373	0.0251721168379202	0.132498824857068
GO:0042162	telomeric DNA binding	10/2503	38/18639	0.263157894736842	1.95964842189373	0.0251721168379202	0.132498824857068
GO:0043531	ADP binding	10/2503	38/18639	0.263157894736842	1.95964842189373	0.0251721168379202	0.132498824857068
GO:0008409	5'-3' exonuclease activity	6/2503	18/18639	0.333333333333333	2.48222133439872	0.0256718165818132	0.132498824857068
GO:0070064	proline-rich region binding	6/2503	18/18639	0.333333333333333	2.48222133439872	0.0256718165818132	0.132498824857068
GO:0098641	cadherin binding involved in cell-cell adhesion	6/2503	18/18639	0.333333333333333	2.48222133439872	0.0256718165818132	0.132498824857068
GO:1990381	ubiquitin-specific protease binding	6/2503	18/18639	0.333333333333333	2.48222133439872	0.0256718165818132	0.132498824857068
GO:0004676	3-phosphoinositide-dependent protein kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0004711	ribosomal protein S6 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0035175	histone H3S10 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0035979	histone H2AXS139 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0044022	histone H3S28 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0044023	histone H4S1 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0044024	histone H2AS1 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0044025	histone H2BS14 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0072354	histone H3T3 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0072371	histone H2AS121 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0072518	Rho-dependent protein serine/threonine kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0140823	histone H2BS36 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0140855	histone H3S57 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0140995	histone H2A kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0140997	histone H4 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0140998	histone H2B kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:1990244	histone H2AT120 kinase activity	44/2503	245/18639	0.179591836734694	1.33736006588013	0.0260920762795457	0.132498824857068
GO:0140416	transcription regulator inhibitor activity	9/2503	33/18639	0.272727272727273	2.03090836450804	0.02634432962134	0.133259254893938
GO:0019903	protein phosphatase binding	28/2503	144/18639	0.194444444444444	1.44796244506592	0.0268198281011012	0.135138668726479
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/2503	28/18639	0.285714285714286	2.12761828662748	0.027080940300553	0.135404701502765
GO:0141052	histone H3 demethylase activity	8/2503	28/18639	0.285714285714286	2.12761828662748	0.027080940300553	0.135404701502765
GO:0140857	histone H3T45 kinase activity	44/2503	246/18639	0.178861788617886	1.33192364284809	0.0277722000945978	0.138328965988418
GO:0004527	exonuclease activity	18/2503	84/18639	0.214285714285714	1.59571371497061	0.0284080802092994	0.140956123175913
GO:0019210	kinase inhibitor activity	19/2503	90/18639	0.211111111111111	1.57207351178586	0.0286611566669174	0.141671116604534
GO:0005525	GTP binding	64/2503	378/18639	0.169312169312169	1.26081083651999	0.0288616758486738	0.142121888648772
GO:0019905	syntaxin binding	14/2503	61/18639	0.229508196721311	1.70907042696305	0.0290892683690077	0.142702071244189
GO:0016791	phosphatase activity	48/2503	273/18639	0.175824175824176	1.30930356100152	0.0295336789696132	0.143808304638879
GO:0035403	histone H3T6 kinase activity	44/2503	247/18639	0.178137651821862	1.32653123943575	0.0295360133373698	0.143808304638879
GO:0000217	DNA secondary structure binding	10/2503	39/18639	0.256410256410256	1.90940102646055	0.0299031052172655	0.144966156481291
GO:0016741	transferase activity, transferring one-carbon groups	39/2503	215/18639	0.181395348837209	1.35079021453326	0.0300011721055447	0.144966156481291
GO:0050840	extracellular matrix binding	15/2503	67/18639	0.223880597014925	1.66716358280511	0.0301083555768835	0.144966156481291
GO:0005161	platelet-derived growth factor receptor binding	5/2503	14/18639	0.357142857142857	2.65952285828434	0.0305148989634328	0.14541637768879
GO:0061665	SUMO ligase activity	5/2503	14/18639	0.357142857142857	2.65952285828434	0.0305148989634328	0.14541637768879
GO:0043021	ribonucleoprotein complex binding	33/2503	177/18639	0.186440677966102	1.38836108534166	0.0305374393146459	0.14541637768879
GO:0004679	AMP-activated protein kinase activity	44/2503	248/18639	0.17741935483871	1.32118232314771	0.0313860825783868	0.148912070627382
GO:0035173	histone kinase activity	61/2503	360/18639	0.169444444444444	1.26179584498602	0.0317669108818724	0.149105573718227
GO:0019001	guanyl nucleotide binding	67/2503	400/18639	0.1675	1.24731622053536	0.0317709568614992	0.149105573718227
GO:0032561	guanyl ribonucleotide binding	67/2503	400/18639	0.1675	1.24731622053536	0.0317709568614992	0.149105573718227
GO:0030506	ankyrin binding	6/2503	19/18639	0.315789473684211	2.35157810627247	0.0333674211028026	0.155531633960063
GO:0008168	methyltransferase activity	37/2503	204/18639	0.181372549019608	1.35062043195225	0.0338587207869001	0.155531633960063
GO:0030215	semaphorin receptor binding	7/2503	24/18639	0.291666666666667	2.17194366759888	0.0338817294048543	0.155531633960063
GO:0003678	DNA helicase activity	16/2503	74/18639	0.216216216216216	1.61008951420458	0.0346200859577148	0.155531633960063
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0030957	Tat protein binding	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0031434	mitogen-activated protein kinase kinase binding	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0031720	haptoglobin binding	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0141109	transporter activator activity	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/2503	10/18639	0.4	2.97866560127847	0.0348151580633679	0.155531633960063
GO:0004725	protein tyrosine phosphatase activity	20/2503	98/18639	0.204081632653061	1.51972734759105	0.0351178733670092	0.156306380887301
GO:0032451	demethylase activity	10/2503	40/18639	0.25	1.86166600079904	0.0352290535384454	0.156306380887301
GO:0042578	phosphoric ester hydrolase activity	61/2503	363/18639	0.168044077134986	1.25136778015142	0.0367743194966197	0.162607535189135
GO:0019208	phosphatase regulator activity	23/2503	117/18639	0.196581196581197	1.46387412028643	0.037354300653286	0.163855736282859
GO:1990782	protein tyrosine kinase binding	23/2503	117/18639	0.196581196581197	1.46387412028643	0.037354300653286	0.163855736282859
GO:0016887	ATP hydrolysis activity	69/2503	417/18639	0.165467625899281	1.2321818134785	0.0374347335969301	0.163855736282859
GO:0140566	histone reader activity	9/2503	35/18639	0.257142857142857	1.91485645796473	0.0377418631318111	0.164645711648841
GO:0030291	protein serine/threonine kinase inhibitor activity	11/2503	46/18639	0.239130434782609	1.7807240007643	0.0378992234020212	0.164779232182701
GO:0008187	poly-pyrimidine tract binding	8/2503	30/18639	0.266666666666667	1.98577706751898	0.0400278903298356	0.173454191429288
GO:0005523	tropomyosin binding	5/2503	15/18639	0.333333333333333	2.48222133439872	0.0408391293453441	0.174068420160483
GO:0031005	filamin binding	5/2503	15/18639	0.333333333333333	2.48222133439872	0.0408391293453441	0.174068420160483
GO:0050780	dopamine receptor binding	5/2503	15/18639	0.333333333333333	2.48222133439872	0.0408391293453441	0.174068420160483
GO:0141050	histone H3K deacetylase activity	5/2503	15/18639	0.333333333333333	2.48222133439872	0.0408391293453441	0.174068420160483
GO:0141051	histone H4K deacetylase activity	5/2503	15/18639	0.333333333333333	2.48222133439872	0.0408391293453441	0.174068420160483
GO:0061659	ubiquitin-like protein ligase activity	62/2503	372/18639	0.166666666666667	1.24111066719936	0.0410125475778483	0.174236313239225
GO:0001727	lipid kinase activity	10/2503	41/18639	0.24390243902439	1.81625951297467	0.0411801000678928	0.174378273903129
GO:0019211	phosphatase activator activity	7/2503	25/18639	0.28	2.08506592089493	0.0417747947181936	0.175751563539326
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	7/2503	25/18639	0.28	2.08506592089493	0.0417747947181936	0.175751563539326
GO:0031418	L-ascorbic acid binding	6/2503	20/18639	0.3	2.23399920095885	0.0424108782232044	0.176813046202694
GO:0043024	ribosomal small subunit binding	6/2503	20/18639	0.3	2.23399920095885	0.0424108782232044	0.176813046202694
GO:0043130	ubiquitin binding	20/2503	100/18639	0.2	1.48933280063923	0.0424351310886466	0.176813046202694
GO:0001784	phosphotyrosine residue binding	11/2503	47/18639	0.234042553191489	1.74283625606719	0.043691024973264	0.180312166556328
GO:0061749	forked DNA-dependent helicase activity	11/2503	47/18639	0.234042553191489	1.74283625606719	0.043691024973264	0.180312166556328
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/2503	47/18639	0.234042553191489	1.74283625606719	0.043691024973264	0.180312166556328
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	18/2503	89/18639	0.202247191011236	1.50606687705091	0.0475070155499201	0.193770739819624
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	18/2503	89/18639	0.202247191011236	1.50606687705091	0.0475070155499201	0.193770739819624
GO:0008307	structural constituent of muscle	10/2503	42/18639	0.238095238095238	1.77301523885623	0.0477828022714677	0.193770739819624
GO:0035198	miRNA binding	10/2503	42/18639	0.238095238095238	1.77301523885623	0.0477828022714677	0.193770739819624
GO:0017147	Wnt-protein binding	8/2503	31/18639	0.258064516129032	1.9217197427603	0.047822444333908	0.193770739819624
GO:0019902	phosphatase binding	34/2503	190/18639	0.178947368421053	1.33256092688773	0.0478464672939225	0.193770739819624
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/2503	11/18639	0.363636363636364	2.70787781934406	0.0490260743395749	0.195502750433888
GO:0008172	S-methyltransferase activity	4/2503	11/18639	0.363636363636364	2.70787781934406	0.0490260743395749	0.195502750433888
GO:0010854	adenylate cyclase regulator activity	4/2503	11/18639	0.363636363636364	2.70787781934406	0.0490260743395749	0.195502750433888
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/2503	11/18639	0.363636363636364	2.70787781934406	0.0490260743395749	0.195502750433888
GO:0032794	GTPase activating protein binding	4/2503	11/18639	0.363636363636364	2.70787781934406	0.0490260743395749	0.195502750433888
GO:0009378	four-way junction helicase activity	11/2503	48/18639	0.229166666666667	1.70652716739912	0.0500620538507807	0.197813586644422
GO:0043138	3'-5' DNA helicase activity	11/2503	48/18639	0.229166666666667	1.70652716739912	0.0500620538507807	0.197813586644422
GO:0140693	molecular condensate scaffold activity	11/2503	48/18639	0.229166666666667	1.70652716739912	0.0500620538507807	0.197813586644422
GO:0140996	histone H3 kinase activity	59/2503	357/18639	0.165266106442577	1.23068116579432	0.0519150916168123	0.204253402777197
GO:0140793	histone H2AXY142 phosphatase activity	18/2503	90/18639	0.2	1.48933280063923	0.052218480270671	0.204253402777197
GO:0098531	ligand-modulated transcription factor activity	13/2503	60/18639	0.216666666666667	1.61344386735917	0.0525521481400655	0.204253402777197
GO:0004860	protein kinase inhibitor activity	17/2503	84/18639	0.202380952380952	1.5070629530278	0.0527375738327279	0.204253402777197
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	6/2503	21/18639	0.285714285714286	2.12761828662748	0.0528517265104462	0.204253402777197
GO:0005123	death receptor binding	6/2503	21/18639	0.285714285714286	2.12761828662748	0.0528517265104462	0.204253402777197
GO:0051010	microtubule plus-end binding	6/2503	21/18639	0.285714285714286	2.12761828662748	0.0528517265104462	0.204253402777197
GO:0019199	transmembrane receptor protein kinase activity	16/2503	78/18639	0.205128205128205	1.52752082116844	0.0530833637085882	0.204253402777197
GO:0017124	SH3 domain binding	22/2503	115/18639	0.191304347826087	1.42457920061144	0.0532491989655045	0.204253402777197
GO:0003774	cytoskeletal motor activity	28/2503	153/18639	0.183006535947712	1.36278818359146	0.0532630027242075	0.204253402777197
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	24/2503	128/18639	0.1875	1.39624950059928	0.0550268531930516	0.210396791620491
GO:0070717	poly-purine tract binding	8/2503	32/18639	0.25	1.86166600079904	0.0565404758004283	0.2155502009987
GO:0072341	modified amino acid binding	18/2503	91/18639	0.197802197802198	1.47296650612671	0.0572489528617221	0.217612978714148
GO:0019209	kinase activator activity	27/2503	148/18639	0.182432432432432	1.35851302761011	0.0587351630310207	0.22261140507384
GO:0005516	calmodulin binding	36/2503	207/18639	0.173913043478261	1.29507200055585	0.0608599856282846	0.229994131734796
GO:0141003	histone H2AX kinase activity	58/2503	354/18639	0.163841807909605	1.22007489317903	0.0613047566834044	0.231003430980944
GO:0044325	transmembrane transporter binding	25/2503	136/18639	0.183823529411765	1.36887205941106	0.0621386233859137	0.233468816189849
GO:0050321	tau-protein kinase activity	6/2503	22/18639	0.272727272727273	2.03090836450804	0.0647174452369848	0.238797092194941
GO:0070034	telomerase RNA binding	6/2503	22/18639	0.272727272727273	2.03090836450804	0.0647174452369848	0.238797092194941
GO:0000340	RNA 7-methylguanosine cap binding	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0000995	RNA polymerase III general transcription initiation factor activity	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0008179	adenylate cyclase binding	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0008603	cAMP-dependent protein kinase regulator activity	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0017166	vinculin binding	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0035197	siRNA binding	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0035497	cAMP response element binding	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0045295	gamma-catenin binding	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0070008	serine-type exopeptidase activity	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0070679	inositol 1,4,5 trisphosphate binding	4/2503	12/18639	0.333333333333333	2.48222133439872	0.0659447354599874	0.238797092194941
GO:0008429	phosphatidylethanolamine binding	5/2503	17/18639	0.294117647058824	2.1901952950577	0.0671026962457546	0.240312686279562
GO:0030169	low-density lipoprotein particle binding	5/2503	17/18639	0.294117647058824	2.1901952950577	0.0671026962457546	0.240312686279562
GO:0038191	neuropilin binding	5/2503	17/18639	0.294117647058824	2.1901952950577	0.0671026962457546	0.240312686279562
GO:1990226	histone methyltransferase binding	5/2503	17/18639	0.294117647058824	2.1901952950577	0.0671026962457546	0.240312686279562
GO:0051213	dioxygenase activity	18/2503	93/18639	0.193548387096774	1.44128980707023	0.0682974350567993	0.24391941091714
GO:0043022	ribosome binding	21/2503	112/18639	0.1875	1.39624950059928	0.069158254896989	0.246317072235851
GO:0019955	cytokine binding	26/2503	144/18639	0.180555555555556	1.34453655613264	0.0693778364873587	0.246424009381329
GO:0046915	transition metal ion transmembrane transporter activity	10/2503	45/18639	0.222222222222222	1.65481422293248	0.0717045809955277	0.253538254789293
GO:0019003	GDP binding	15/2503	75/18639	0.2	1.48933280063923	0.0718071143173655	0.253538254789293
GO:0045499	chemorepellent activity	7/2503	28/18639	0.25	1.86166600079904	0.0721608879015681	0.253538254789293
GO:0097718	disordered domain specific binding	7/2503	28/18639	0.25	1.86166600079904	0.0721608879015681	0.253538254789293
GO:0030544	Hsp70 protein binding	11/2503	51/18639	0.215686274509804	1.60614321637564	0.072820037854668	0.255164553129565
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	16/2503	82/18639	0.195121951219512	1.45300761037974	0.0774694350735574	0.270726520418346
GO:0030331	nuclear estrogen receptor binding	9/2503	40/18639	0.225	1.67549940071914	0.0796089711010726	0.277457540030548
GO:0000900	mRNA regulatory element binding translation repressor activity	5/2503	18/18639	0.277777777777778	2.0685177786656	0.0830376499626553	0.286336724009156
GO:0017075	syntaxin-1 binding	5/2503	18/18639	0.277777777777778	2.0685177786656	0.0830376499626553	0.286336724009156
GO:0030228	lipoprotein particle receptor activity	5/2503	18/18639	0.277777777777778	2.0685177786656	0.0830376499626553	0.286336724009156
GO:1901611	phosphatidylglycerol binding	5/2503	18/18639	0.277777777777778	2.0685177786656	0.0830376499626553	0.286336724009156
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	7/2503	29/18639	0.241379310344828	1.79747062146114	0.0845808240320396	0.287130489914338
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	7/2503	29/18639	0.241379310344828	1.79747062146114	0.0845808240320396	0.287130489914338
GO:0097472	cyclin-dependent protein kinase activity	7/2503	29/18639	0.241379310344828	1.79747062146114	0.0845808240320396	0.287130489914338
GO:0008238	exopeptidase activity	19/2503	102/18639	0.186274509803922	1.38712368686987	0.0850911413579974	0.287130489914338
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/2503	13/18639	0.307692307692308	2.29128123175267	0.085476538151422	0.287130489914338
GO:0005035	death receptor activity	4/2503	13/18639	0.307692307692308	2.29128123175267	0.085476538151422	0.287130489914338
GO:0017154	semaphorin receptor activity	4/2503	13/18639	0.307692307692308	2.29128123175267	0.085476538151422	0.287130489914338
GO:0035673	oligopeptide transmembrane transporter activity	4/2503	13/18639	0.307692307692308	2.29128123175267	0.085476538151422	0.287130489914338
GO:0046974	histone H3K9 methyltransferase activity	4/2503	13/18639	0.307692307692308	2.29128123175267	0.085476538151422	0.287130489914338
GO:0140666	annealing activity	4/2503	13/18639	0.307692307692308	2.29128123175267	0.085476538151422	0.287130489914338
GO:0005154	epidermal growth factor receptor binding	8/2503	35/18639	0.228571428571429	1.70209462930198	0.0884025001818366	0.296193943908216
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/2503	41/18639	0.219512195121951	1.63463356167721	0.0904170910791543	0.300789097024172
GO:0004879	nuclear receptor activity	12/2503	59/18639	0.203389830508475	1.51457572946363	0.0904681053357317	0.300789097024172
GO:0045309	protein phosphorylated amino acid binding	12/2503	59/18639	0.203389830508475	1.51457572946363	0.0904681053357317	0.300789097024172
GO:0004622	lysophospholipase activity	6/2503	24/18639	0.25	1.86166600079904	0.0927241045781877	0.306720956619959
GO:0070840	dynein complex binding	6/2503	24/18639	0.25	1.86166600079904	0.0927241045781877	0.306720956619959
GO:0008083	growth factor activity	28/2503	162/18639	0.172839506172839	1.28707772894749	0.0947642524424103	0.312673929378511
GO:0003924	GTPase activity	53/2503	331/18639	0.16012084592145	1.19236613948458	0.097231075869824	0.320001009191826
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	7/2503	30/18639	0.233333333333333	1.73755493407911	0.0981404125501018	0.321366590214439
GO:0031210	phosphatidylcholine binding	7/2503	30/18639	0.233333333333333	1.73755493407911	0.0981404125501018	0.321366590214439
GO:0008301	DNA binding, bending	5/2503	19/18639	0.263157894736842	1.95964842189373	0.100777017412603	0.328346172021011
GO:1990380	K48-linked deubiquitinase activity	5/2503	19/18639	0.263157894736842	1.95964842189373	0.100777017412603	0.328346172021011
GO:0000287	magnesium ion binding	38/2503	230/18639	0.165217391304348	1.23031840052806	0.101321612331471	0.329295240077282
GO:0051879	Hsp90 protein binding	9/2503	42/18639	0.214285714285714	1.59571371497061	0.102044624390342	0.33081798430784
GO:0061630	ubiquitin protein ligase activity	56/2503	353/18639	0.158640226628895	1.18134046509628	0.102793400790133	0.332416470216847
GO:0043539	protein serine/threonine kinase activator activity	14/2503	73/18639	0.191780821917808	1.42812734307872	0.105213045122218	0.338255573788385
GO:0005344	oxygen carrier activity	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0005347	ATP transmembrane transporter activity	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0005545	1-phosphatidylinositol binding	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0032454	histone H3K9 demethylase activity	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0034236	protein kinase A catalytic subunit binding	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0044548	S100 protein binding	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0046030	inositol trisphosphate phosphatase activity	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0071933	Arp2/3 complex binding	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0098847	sequence-specific single stranded DNA binding	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:1901612	cardiolipin binding	4/2503	14/18639	0.285714285714286	2.12761828662748	0.107461193826618	0.338255573788385
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	16/2503	86/18639	0.186046511627907	1.38542586105975	0.108226513570415	0.339226303166627
GO:0003707	nuclear steroid receptor activity	6/2503	25/18639	0.24	1.78719936076708	0.108813360323449	0.339226303166627
GO:0015662	P-type ion transporter activity	6/2503	25/18639	0.24	1.78719936076708	0.108813360323449	0.339226303166627
GO:0140358	P-type transmembrane transporter activity	6/2503	25/18639	0.24	1.78719936076708	0.108813360323449	0.339226303166627
GO:0015026	coreceptor activity	12/2503	61/18639	0.19672131147541	1.46491750882548	0.109997808893404	0.342098448711545
GO:0046982	protein heterodimerization activity	58/2503	369/18639	0.157181571815718	1.1704783528059	0.111662084946077	0.346445609617901
GO:0008374	O-acyltransferase activity	11/2503	55/18639	0.2	1.48933280063923	0.112002616741486	0.346674766104599
GO:0060590	ATPase regulator activity	10/2503	49/18639	0.204081632653061	1.51972734759105	0.113569465841079	0.350689561979579
GO:0030295	protein kinase activator activity	24/2503	139/18639	0.172661870503597	1.28575493580365	0.115805125147334	0.35674564618847
GO:0000339	RNA cap binding	5/2503	20/18639	0.25	1.86166600079904	0.120232397142402	0.359671981718735
GO:0030742	GTP-dependent protein binding	5/2503	20/18639	0.25	1.86166600079904	0.120232397142402	0.359671981718735
GO:0052745	inositol phosphate phosphatase activity	5/2503	20/18639	0.25	1.86166600079904	0.120232397142402	0.359671981718735
GO:0061608	nuclear import signal receptor activity	5/2503	20/18639	0.25	1.86166600079904	0.120232397142402	0.359671981718735
GO:0140939	histone H4 methyltransferase activity	5/2503	20/18639	0.25	1.86166600079904	0.120232397142402	0.359671981718735
GO:0030971	receptor tyrosine kinase binding	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0033192	calmodulin-dependent protein phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0140791	histone H2AXS140 phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:1990439	MAP kinase serine/threonine phosphatase activity	15/2503	81/18639	0.185185185185185	1.37901185244373	0.12062844925336	0.359671981718735
GO:0019888	protein phosphatase regulator activity	19/2503	107/18639	0.177570093457944	1.32230482299745	0.122000436108815	0.362930359133774
GO:0004435	phosphatidylinositol phospholipase C activity	6/2503	26/18639	0.230769230769231	1.7184609238145	0.126227036511156	0.371255989738693
GO:0008143	poly(A) binding	6/2503	26/18639	0.230769230769231	1.7184609238145	0.126227036511156	0.371255989738693
GO:0008157	protein phosphatase 1 binding	6/2503	26/18639	0.230769230769231	1.7184609238145	0.126227036511156	0.371255989738693
GO:0052742	phosphatidylinositol kinase activity	6/2503	26/18639	0.230769230769231	1.7184609238145	0.126227036511156	0.371255989738693
GO:0070412	R-SMAD binding	6/2503	26/18639	0.230769230769231	1.7184609238145	0.126227036511156	0.371255989738693
GO:0043425	bHLH transcription factor binding	7/2503	32/18639	0.21875	1.62895775069916	0.128573769640723	0.376253398642385
GO:0140142	nucleocytoplasmic carrier activity	7/2503	32/18639	0.21875	1.62895775069916	0.128573769640723	0.376253398642385
GO:0000146	microfilament motor activity	8/2503	38/18639	0.210526315789474	1.56771873751498	0.128794432612201	0.376253398642385
GO:0033549	MAP kinase phosphatase activity	15/2503	82/18639	0.182926829268293	1.36219463473101	0.13029091511451	0.379771725670098
GO:0004129	cytochrome-c oxidase activity	4/2503	15/18639	0.266666666666667	1.98577706751898	0.131687399092535	0.381277547483956
GO:0004559	alpha-mannosidase activity	4/2503	15/18639	0.266666666666667	1.98577706751898	0.131687399092535	0.381277547483956
GO:0005041	low-density lipoprotein particle receptor activity	4/2503	15/18639	0.266666666666667	1.98577706751898	0.131687399092535	0.381277547483956
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	15/2503	83/18639	0.180722891566265	1.34578265118003	0.140380516185987	0.392469046430246
GO:0001094	TFIID-class transcription factor complex binding	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0005031	tumor necrosis factor receptor activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0005345	purine nucleobase transmembrane transporter activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0005381	iron ion transmembrane transporter activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0008239	dipeptidyl-peptidase activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0043121	neurotrophin binding	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0043422	protein kinase B binding	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0045322	unmethylated CpG binding	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0070097	delta-catenin binding	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0140940	histone H2A methyltransferase activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:1990259	histone H2AQ104 methyltransferase activity	3/2503	10/18639	0.3	2.23399920095885	0.140709221787152	0.392469046430246
GO:0072542	protein phosphatase activator activity	5/2503	21/18639	0.238095238095238	1.77301523885623	0.141288856714889	0.392469046430246
GO:0140312	cargo adaptor activity	5/2503	21/18639	0.238095238095238	1.77301523885623	0.141288856714889	0.392469046430246
GO:0004722	protein serine/threonine phosphatase activity	18/2503	103/18639	0.174757281553398	1.30135875784011	0.144384946874209	0.399921135752837
GO:0001671	ATPase activator activity	6/2503	27/18639	0.222222222222222	1.65481422293248	0.144894503799682	0.399921135752837
GO:0008266	poly(U) RNA binding	6/2503	27/18639	0.222222222222222	1.65481422293248	0.144894503799682	0.399921135752837
GO:0071889	14-3-3 protein binding	7/2503	33/18639	0.212121212121212	1.57959539461737	0.145365834619219	0.400372002129204
GO:0008408	3'-5' exonuclease activity	11/2503	58/18639	0.189655172413793	1.41229834543376	0.147965601162008	0.405812830191162
GO:0017116	single-stranded DNA helicase activity	11/2503	58/18639	0.189655172413793	1.41229834543376	0.147965601162008	0.405812830191162
GO:0017018	myosin phosphatase activity	15/2503	84/18639	0.178571428571429	1.32976142914217	0.150889977504307	0.412962043695998
GO:0015562	efflux transmembrane transporter activity	4/2503	16/18639	0.25	1.86166600079904	0.157906763884801	0.42588961213743
GO:0015923	mannosidase activity	4/2503	16/18639	0.25	1.86166600079904	0.157906763884801	0.42588961213743
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/2503	16/18639	0.25	1.86166600079904	0.157906763884801	0.42588961213743
GO:0022841	potassium ion leak channel activity	4/2503	16/18639	0.25	1.86166600079904	0.157906763884801	0.42588961213743
GO:0030275	LRR domain binding	4/2503	16/18639	0.25	1.86166600079904	0.157906763884801	0.42588961213743
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2503	16/18639	0.25	1.86166600079904	0.157906763884801	0.42588961213743
GO:0097027	ubiquitin-protein transferase activator activity	4/2503	16/18639	0.25	1.86166600079904	0.157906763884801	0.42588961213743
GO:0004407	histone deacetylase activity	5/2503	22/18639	0.227272727272727	1.69242363709004	0.163809860090742	0.439733527410508
GO:0033558	protein lysine deacetylase activity	5/2503	22/18639	0.227272727272727	1.69242363709004	0.163809860090742	0.439733527410508
GO:0005242	inward rectifier potassium channel activity	6/2503	28/18639	0.214285714285714	1.59571371497061	0.164730944499167	0.439733527410508
GO:0046875	ephrin receptor binding	6/2503	28/18639	0.214285714285714	1.59571371497061	0.164730944499167	0.439733527410508
GO:0051019	mitogen-activated protein kinase binding	6/2503	28/18639	0.214285714285714	1.59571371497061	0.164730944499167	0.439733527410508
GO:0008235	metalloexopeptidase activity	12/2503	66/18639	0.181818181818182	1.35393890967203	0.168557090551313	0.449025036304727
GO:0008432	JUN kinase binding	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0015205	nucleobase transmembrane transporter activity	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0015217	ADP transmembrane transporter activity	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0019107	myristoyltransferase activity	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0019215	intermediate filament binding	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0032050	clathrin heavy chain binding	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0034713	type I transforming growth factor beta receptor binding	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0043522	leucine zipper domain binding	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0045294	alpha-catenin binding	3/2503	11/18639	0.272727272727273	2.03090836450804	0.175090402079993	0.455235045407982
GO:0034061	DNA polymerase activity	7/2503	35/18639	0.2	1.48933280063923	0.181819647874014	0.471787509453529
GO:0004629	phospholipase C activity	6/2503	29/18639	0.206896551724138	1.54068910410955	0.185639671577548	0.476529428216686
GO:0099604	ligand-gated calcium channel activity	6/2503	29/18639	0.206896551724138	1.54068910410955	0.185639671577548	0.476529428216686
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/2503	17/18639	0.235294117647059	1.75215623604616	0.185846477004507	0.476529428216686
GO:0005092	GDP-dissociation inhibitor activity	4/2503	17/18639	0.235294117647059	1.75215623604616	0.185846477004507	0.476529428216686
GO:0019198	transmembrane receptor protein phosphatase activity	4/2503	17/18639	0.235294117647059	1.75215623604616	0.185846477004507	0.476529428216686
GO:0046965	nuclear retinoid X receptor binding	4/2503	17/18639	0.235294117647059	1.75215623604616	0.185846477004507	0.476529428216686
GO:0003887	DNA-directed DNA polymerase activity	5/2503	23/18639	0.217391304347826	1.61884000069482	0.187642179342378	0.480186679419472
GO:0001618	virus receptor activity	14/2503	81/18639	0.172839506172839	1.28707772894749	0.192671856827173	0.492089221758988
GO:0042056	chemoattractant activity	8/2503	42/18639	0.19047619047619	1.41841219108498	0.194747714031059	0.496415741647797
GO:0055106	ubiquitin-protein transferase regulator activity	7/2503	36/18639	0.194444444444444	1.44796244506592	0.201343339303331	0.512223759480097
GO:0035591	signaling adaptor activity	21/2503	129/18639	0.162790697674419	1.21224762842728	0.202216303591566	0.51343983333796
GO:0140272	exogenous protein binding	14/2503	82/18639	0.170731707317073	1.27138165908227	0.205514991885662	0.520798225051387
GO:0015215	nucleotide transmembrane transporter activity	6/2503	30/18639	0.2	1.48933280063923	0.20751448633441	0.524842086059792
GO:0005095	GTPase inhibitor activity	3/2503	12/18639	0.25	1.86166600079904	0.211472290953328	0.527665985104274
GO:0005247	voltage-gated chloride channel activity	3/2503	12/18639	0.25	1.86166600079904	0.211472290953328	0.527665985104274
GO:0016208	AMP binding	3/2503	12/18639	0.25	1.86166600079904	0.211472290953328	0.527665985104274
GO:0035259	nuclear glucocorticoid receptor binding	3/2503	12/18639	0.25	1.86166600079904	0.211472290953328	0.527665985104274
GO:0036009	protein-glutamine N-methyltransferase activity	3/2503	12/18639	0.25	1.86166600079904	0.211472290953328	0.527665985104274
GO:0043047	single-stranded telomeric DNA binding	3/2503	12/18639	0.25	1.86166600079904	0.211472290953328	0.527665985104274
GO:0097677	STAT family protein binding	3/2503	12/18639	0.25	1.86166600079904	0.211472290953328	0.527665985104274
GO:0035035	histone acetyltransferase binding	5/2503	24/18639	0.208333333333333	1.5513883339992	0.212620620069796	0.528502497305421
GO:0070300	phosphatidic acid binding	5/2503	24/18639	0.208333333333333	1.5513883339992	0.212620620069796	0.528502497305421
GO:0008200	ion channel inhibitor activity	8/2503	43/18639	0.186046511627907	1.38542586105975	0.213094208004985	0.528668836653589
GO:0004706	JUN kinase kinase kinase activity	4/2503	18/18639	0.222222222222222	1.65481422293248	0.215220427587894	0.530904280577347
GO:0008525	phosphatidylcholine transporter activity	4/2503	18/18639	0.222222222222222	1.65481422293248	0.215220427587894	0.530904280577347
GO:0035615	clathrin adaptor activity	4/2503	18/18639	0.222222222222222	1.65481422293248	0.215220427587894	0.530904280577347
GO:0042277	peptide binding	38/2503	249/18639	0.152610441767068	1.13643868321869	0.220767833270548	0.543557165249456
GO:0008327	methyl-CpG binding	6/2503	31/18639	0.193548387096774	1.44128980707023	0.23024200626751	0.564744543675025
GO:0072349	modified amino acid transmembrane transporter activity	6/2503	31/18639	0.193548387096774	1.44128980707023	0.23024200626751	0.564744543675025
GO:0016248	channel inhibitor activity	8/2503	44/18639	0.181818181818182	1.35393890967203	0.232067922001708	0.567647501346474
GO:0051117	ATPase binding	14/2503	84/18639	0.166666666666667	1.24111066719936	0.232298823627942	0.567647501346474
GO:0070851	growth factor receptor binding	22/2503	139/18639	0.158273381294964	1.17860869115335	0.234934043632244	0.573009862517669
GO:0004518	nuclease activity	32/2503	209/18639	0.15311004784689	1.14015908182908	0.237933418782388	0.57434104723759
GO:0000030	mannosyltransferase activity	5/2503	25/18639	0.2	1.48933280063923	0.238572435006384	0.57434104723759
GO:0004709	MAP kinase kinase kinase activity	5/2503	25/18639	0.2	1.48933280063923	0.238572435006384	0.57434104723759
GO:0005537	D-mannose binding	5/2503	25/18639	0.2	1.48933280063923	0.238572435006384	0.57434104723759
GO:0008139	nuclear localization sequence binding	5/2503	25/18639	0.2	1.48933280063923	0.238572435006384	0.57434104723759
GO:0015271	outward rectifier potassium channel activity	5/2503	25/18639	0.2	1.48933280063923	0.238572435006384	0.57434104723759
GO:0017025	TBP-class protein binding	5/2503	25/18639	0.2	1.48933280063923	0.238572435006384	0.57434104723759
GO:0005272	sodium channel activity	9/2503	51/18639	0.176470588235294	1.31411717703462	0.240010250379522	0.576734427899037
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	7/2503	38/18639	0.184210526315789	1.37175389532561	0.242590825297225	0.581859913074525
GO:0004713	protein tyrosine kinase activity	22/2503	140/18639	0.157142857142857	1.17019005764511	0.245691258308149	0.584022433988476
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/2503	19/18639	0.210526315789474	1.56771873751498	0.245738670301305	0.584022433988476
GO:0022840	leak channel activity	4/2503	19/18639	0.210526315789474	1.56771873751498	0.245738670301305	0.584022433988476
GO:0022842	narrow pore channel activity	4/2503	19/18639	0.210526315789474	1.56771873751498	0.245738670301305	0.584022433988476
GO:0042834	peptidoglycan binding	4/2503	19/18639	0.210526315789474	1.56771873751498	0.245738670301305	0.584022433988476
GO:0004535	poly(A)-specific ribonuclease activity	3/2503	13/18639	0.230769230769231	1.7184609238145	0.2492710167939	0.590259238309782
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/2503	13/18639	0.230769230769231	1.7184609238145	0.2492710167939	0.590259238309782
GO:0141110	transporter inhibitor activity	8/2503	45/18639	0.177777777777778	1.32385137834598	0.251603802753258	0.594699897416792
GO:0000149	SNARE binding	17/2503	106/18639	0.160377358490566	1.19427630239938	0.252325514876197	0.595323356332224
GO:0051059	NF-kappaB binding	6/2503	32/18639	0.1875	1.39624950059928	0.253703907027539	0.595334077862455
GO:0071813	lipoprotein particle binding	6/2503	32/18639	0.1875	1.39624950059928	0.253703907027539	0.595334077862455
GO:0071814	protein-lipid complex binding	6/2503	32/18639	0.1875	1.39624950059928	0.253703907027539	0.595334077862455
GO:0019783	ubiquitin-like protein peptidase activity	20/2503	127/18639	0.15748031496063	1.17270299262932	0.255542899784121	0.598568954449292
GO:0005112	Notch binding	5/2503	26/18639	0.192307692307692	1.43205076984542	0.265321339410009	0.618132152747333
GO:0015216	purine nucleotide transmembrane transporter activity	5/2503	26/18639	0.192307692307692	1.43205076984542	0.265321339410009	0.618132152747333
GO:0043548	phosphatidylinositol 3-kinase binding	5/2503	26/18639	0.192307692307692	1.43205076984542	0.265321339410009	0.618132152747333
GO:0008017	microtubule binding	41/2503	276/18639	0.148550724637681	1.10620733380813	0.266210773448801	0.619094821973955
GO:0008237	metallopeptidase activity	28/2503	184/18639	0.152173913043478	1.13318800048637	0.266716935946572	0.619164315590257
GO:0008081	phosphoric diester hydrolase activity	14/2503	87/18639	0.160919540229885	1.19831374764076	0.274897620441176	0.636549424763109
GO:0010851	cyclase regulator activity	4/2503	20/18639	0.2	1.48933280063923	0.27711523859103	0.636549424763109
GO:0015095	magnesium ion transmembrane transporter activity	4/2503	20/18639	0.2	1.48933280063923	0.27711523859103	0.636549424763109
GO:0016004	phospholipase activator activity	4/2503	20/18639	0.2	1.48933280063923	0.27711523859103	0.636549424763109
GO:0042288	MHC class I protein binding	4/2503	20/18639	0.2	1.48933280063923	0.27711523859103	0.636549424763109
GO:0005544	calcium-dependent phospholipid binding	9/2503	53/18639	0.169811320754717	1.26452784959935	0.277143826473785	0.636549424763109
GO:0101005	deubiquitinase activity	18/2503	115/18639	0.156521739130435	1.16556480050027	0.27872721452676	0.638744772706813
GO:0015631	tubulin binding	56/2503	385/18639	0.145454545454545	1.08315112773762	0.279082331459592	0.638744772706813
GO:0004532	RNA exonuclease activity	7/2503	40/18639	0.175	1.30316620055933	0.286196734805244	0.642076071998312
GO:0050997	quaternary ammonium group binding	7/2503	40/18639	0.175	1.30316620055933	0.286196734805244	0.642076071998312
GO:0003684	damaged DNA binding	12/2503	74/18639	0.162162162162162	1.20756713565343	0.286666513678698	0.642076071998312
GO:0008174	mRNA methyltransferase activity	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0008331	high voltage-gated calcium channel activity	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0008474	palmitoyl-(protein) hydrolase activity	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0008494	translation activator activity	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0008559	ABC-type xenobiotic transporter activity	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0019992	diacylglycerol binding	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0042043	neurexin family protein binding	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0070742	C2H2 zinc finger domain binding	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0098599	palmitoyl hydrolase activity	3/2503	14/18639	0.214285714285714	1.59571371497061	0.287946423057705	0.642076071998312
GO:0004620	phospholipase activity	17/2503	109/18639	0.155963302752294	1.16140631242509	0.291449275508318	0.648774072193173
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/2503	54/18639	0.166666666666667	1.24111066719936	0.296294531145947	0.658432291435437
GO:0140223	general transcription initiation factor activity	11/2503	68/18639	0.161764705882353	1.20460741228173	0.30147525930866	0.668801769797368
GO:0005248	voltage-gated sodium channel activity	4/2503	21/18639	0.19047619047619	1.41841219108498	0.309074387267769	0.679859058287818
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/2503	21/18639	0.19047619047619	1.41841219108498	0.309074387267769	0.679859058287818
GO:0019200	carbohydrate kinase activity	4/2503	21/18639	0.19047619047619	1.41841219108498	0.309074387267769	0.679859058287818
GO:0035613	RNA stem-loop binding	4/2503	21/18639	0.19047619047619	1.41841219108498	0.309074387267769	0.679859058287818
GO:0070182	DNA polymerase binding	4/2503	21/18639	0.19047619047619	1.41841219108498	0.309074387267769	0.679859058287818
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/2503	15/18639	0.2	1.48933280063923	0.327011179048997	0.712673728353518
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/2503	15/18639	0.2	1.48933280063923	0.327011179048997	0.712673728353518
GO:0004953	icosanoid receptor activity	3/2503	15/18639	0.2	1.48933280063923	0.327011179048997	0.712673728353518
GO:0045504	dynein heavy chain binding	3/2503	15/18639	0.2	1.48933280063923	0.327011179048997	0.712673728353518
GO:0120283	protein serine/threonine kinase binding	3/2503	15/18639	0.2	1.48933280063923	0.327011179048997	0.712673728353518
GO:0000175	3'-5'-RNA exonuclease activity	6/2503	35/18639	0.171428571428571	1.27657097197649	0.327281704482346	0.712673728353518
GO:0019212	phosphatase inhibitor activity	9/2503	56/18639	0.160714285714286	1.19678528622796	0.335479660332156	0.72930360941773
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2503	22/18639	0.181818181818182	1.35393890967203	0.341355393307109	0.739603352165402
GO:0031683	G-protein beta/gamma-subunit complex binding	4/2503	22/18639	0.181818181818182	1.35393890967203	0.341355393307109	0.739603352165402
GO:0005539	glycosaminoglycan binding	35/2503	242/18639	0.144628099173554	1.07699685996639	0.344913055704372	0.746068173736579
GO:0043236	laminin binding	5/2503	29/18639	0.172413793103448	1.28390758675796	0.348606165823023	0.752804012574635
GO:0140299	molecular sensor activity	11/2503	71/18639	0.154929577464789	1.15370850753743	0.354250467527124	0.762898669170372
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/2503	43/18639	0.162790697674419	1.21224762842728	0.354454458599157	0.762898669170372
GO:0032813	tumor necrosis factor receptor superfamily binding	8/2503	50/18639	0.16	1.19146624051139	0.355296981676249	0.763448059800204
GO:0030246	carbohydrate binding	40/2503	280/18639	0.142857142857143	1.06380914331374	0.361733676133135	0.775996334939068
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/2503	16/18639	0.1875	1.39624950059928	0.366035274856119	0.77879845714068
GO:0004707	MAP kinase activity	3/2503	16/18639	0.1875	1.39624950059928	0.366035274856119	0.77879845714068
GO:0004708	MAP kinase kinase activity	3/2503	16/18639	0.1875	1.39624950059928	0.366035274856119	0.77879845714068
GO:0005159	insulin-like growth factor receptor binding	3/2503	16/18639	0.1875	1.39624950059928	0.366035274856119	0.77879845714068
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2503	16/18639	0.1875	1.39624950059928	0.366035274856119	0.77879845714068
GO:0099094	ligand-gated monoatomic cation channel activity	20/2503	136/18639	0.147058823529412	1.09509764752885	0.367166160337554	0.779928118364084
GO:0000295	adenine nucleotide transmembrane transporter activity	4/2503	23/18639	0.173913043478261	1.29507200055585	0.373716069931263	0.78780697983687
GO:0005283	amino acid:sodium symporter activity	4/2503	23/18639	0.173913043478261	1.29507200055585	0.373716069931263	0.78780697983687
GO:0016917	GABA receptor activity	4/2503	23/18639	0.173913043478261	1.29507200055585	0.373716069931263	0.78780697983687
GO:0017134	fibroblast growth factor binding	4/2503	23/18639	0.173913043478261	1.29507200055585	0.373716069931263	0.78780697983687
GO:0019843	rRNA binding	10/2503	65/18639	0.153846153846154	1.14564061587633	0.37390531273796	0.78780697983687
GO:0022839	monoatomic ion-gated channel activity	5/2503	30/18639	0.166666666666667	1.24111066719936	0.376824501720745	0.7917623908613
GO:0004843	cysteine-type deubiquitinase activity	16/2503	108/18639	0.148148148148148	1.10320948195499	0.377000707648573	0.7917623908613
GO:0019213	deacetylase activity	6/2503	37/18639	0.162162162162162	1.20756713565343	0.377793450862072	0.792147558259184
GO:0015459	potassium channel regulator activity	9/2503	59/18639	0.152542372881356	1.13593179709772	0.395609375295834	0.812349707533999
GO:0000182	rDNA binding	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0004090	carbonyl reductase (NADPH) activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0005337	nucleoside transmembrane transporter activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0005522	profilin binding	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0008140	cAMP response element binding protein binding	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0015279	store-operated calcium channel activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0043295	glutathione binding	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0098505	G-rich strand telomeric DNA binding	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:1990757	ubiquitin ligase activator activity	2/2503	10/18639	0.2	1.48933280063923	0.396801587910838	0.812349707533999
GO:0004857	enzyme inhibitor activity	58/2503	416/18639	0.139423076923077	1.03823680813793	0.399808876268021	0.814376092399109
GO:0004197	cysteine-type endopeptidase activity	13/2503	88/18639	0.147727272727273	1.10007536410852	0.401304752929566	0.814376092399109
GO:0140098	catalytic activity, acting on RNA	54/2503	387/18639	0.13953488372093	1.03906939579481	0.402387333943501	0.814376092399109
GO:0016018	cyclosporin A binding	3/2503	17/18639	0.176470588235294	1.31411717703462	0.404647160110036	0.814376092399109
GO:0031489	myosin V binding	3/2503	17/18639	0.176470588235294	1.31411717703462	0.404647160110036	0.814376092399109
GO:0051787	misfolded protein binding	3/2503	17/18639	0.176470588235294	1.31411717703462	0.404647160110036	0.814376092399109
GO:0005452	solute:inorganic anion antiporter activity	5/2503	31/18639	0.161290322580645	1.20107483922519	0.40501344315406	0.814376092399109
GO:0070325	lipoprotein particle receptor binding	5/2503	31/18639	0.161290322580645	1.20107483922519	0.40501344315406	0.814376092399109
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/2503	24/18639	0.166666666666667	1.24111066719936	0.405935159903556	0.814376092399109
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/2503	24/18639	0.166666666666667	1.24111066719936	0.405935159903556	0.814376092399109
GO:0005315	phosphate transmembrane transporter activity	4/2503	24/18639	0.166666666666667	1.24111066719936	0.405935159903556	0.814376092399109
GO:0030552	cAMP binding	4/2503	24/18639	0.166666666666667	1.24111066719936	0.405935159903556	0.814376092399109
GO:0060229	lipase activator activity	4/2503	24/18639	0.166666666666667	1.24111066719936	0.405935159903556	0.814376092399109
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/2503	60/18639	0.15	1.11699960047942	0.415789292742064	0.832859908420159
GO:0022853	active monoatomic ion transmembrane transporter activity	17/2503	118/18639	0.144067796610169	1.07282447503674	0.417351074050618	0.834702148101236
GO:0004864	protein phosphatase inhibitor activity	8/2503	53/18639	0.150943396226415	1.12402475519942	0.419803143923409	0.837030808436245
GO:1901505	carbohydrate derivative transmembrane transporter activity	8/2503	53/18639	0.150943396226415	1.12402475519942	0.419803143923409	0.837030808436245
GO:0030145	manganese ion binding	10/2503	68/18639	0.147058823529412	1.09509764752885	0.430995427259268	0.85656124433235
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/2503	25/18639	0.16	1.19146624051139	0.437813774169684	0.85656124433235
GO:0000400	four-way junction DNA binding	3/2503	18/18639	0.166666666666667	1.24111066719936	0.442532506614464	0.85656124433235
GO:0008308	voltage-gated monoatomic anion channel activity	3/2503	18/18639	0.166666666666667	1.24111066719936	0.442532506614464	0.85656124433235
GO:0031690	adrenergic receptor binding	3/2503	18/18639	0.166666666666667	1.24111066719936	0.442532506614464	0.85656124433235
GO:0034185	apolipoprotein binding	3/2503	18/18639	0.166666666666667	1.24111066719936	0.442532506614464	0.85656124433235
GO:0017022	myosin binding	11/2503	76/18639	0.144736842105263	1.07780663204155	0.444433016672106	0.85656124433235
GO:0042626	ATPase-coupled transmembrane transporter activity	14/2503	98/18639	0.142857142857143	1.06380914331374	0.445703765438159	0.85656124433235
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0001851	complement component C3b binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0002162	dystroglycan binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0004954	prostanoid receptor activity	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0005225	volume-sensitive anion channel activity	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0005536	D-glucose binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0008046	axon guidance receptor activity	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0008503	benzodiazepine receptor activity	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0008526	phosphatidylinositol transfer activity	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0019864	IgG binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0034056	estrogen response element binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0042608	T cell receptor binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0050998	nitric-oxide synthase binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0070990	snRNP binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0140031	phosphorylation-dependent protein binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:1900750	oligopeptide binding	2/2503	11/18639	0.181818181818182	1.35393890967203	0.446070740317693	0.85656124433235
GO:0004540	RNA nuclease activity	17/2503	121/18639	0.140495867768595	1.0462255211102	0.46042849600275	0.882157752603092
GO:0019956	chemokine binding	5/2503	33/18639	0.151515151515152	1.12828242472669	0.460757780013461	0.882157752603092
GO:0043178	alcohol binding	13/2503	92/18639	0.141304347826087	1.05224600045163	0.467400609733671	0.887814913457938
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/2503	26/18639	0.153846153846154	1.14564061587633	0.46917603503508	0.887814913457938
GO:0005227	calcium-activated cation channel activity	4/2503	26/18639	0.153846153846154	1.14564061587633	0.46917603503508	0.887814913457938
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/2503	26/18639	0.153846153846154	1.14564061587633	0.46917603503508	0.887814913457938
GO:0008198	ferrous iron binding	4/2503	26/18639	0.153846153846154	1.14564061587633	0.46917603503508	0.887814913457938
GO:0030247	polysaccharide binding	4/2503	26/18639	0.153846153846154	1.14564061587633	0.46917603503508	0.887814913457938
GO:0030507	spectrin binding	4/2503	26/18639	0.153846153846154	1.14564061587633	0.46917603503508	0.887814913457938
GO:0050750	low-density lipoprotein particle receptor binding	4/2503	26/18639	0.153846153846154	1.14564061587633	0.46917603503508	0.887814913457938
GO:0015399	primary active transmembrane transporter activity	23/2503	166/18639	0.13855421686747	1.03176669923802	0.470103397964161	0.888276769409025
GO:0004812	aminoacyl-tRNA ligase activity	6/2503	41/18639	0.146341463414634	1.0897557077848	0.478346605097405	0.894204815208229
GO:0016875	ligase activity, forming carbon-oxygen bonds	6/2503	41/18639	0.146341463414634	1.0897557077848	0.478346605097405	0.894204815208229
GO:0042287	MHC protein binding	6/2503	41/18639	0.146341463414634	1.0897557077848	0.478346605097405	0.894204815208229
GO:0061650	ubiquitin-like protein conjugating enzyme activity	6/2503	41/18639	0.146341463414634	1.0897557077848	0.478346605097405	0.894204815208229
GO:0140318	protein transporter activity	6/2503	41/18639	0.146341463414634	1.0897557077848	0.478346605097405	0.894204815208229
GO:0005520	insulin-like growth factor binding	3/2503	19/18639	0.157894736842105	1.17578905313624	0.479431350923181	0.894204815208229
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2503	19/18639	0.157894736842105	1.17578905313624	0.479431350923181	0.894204815208229
GO:0046624	sphingolipid transporter activity	3/2503	19/18639	0.157894736842105	1.17578905313624	0.479431350923181	0.894204815208229
GO:0140036	ubiquitin-modified protein reader activity	3/2503	19/18639	0.157894736842105	1.17578905313624	0.479431350923181	0.894204815208229
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	5/2503	34/18639	0.147058823529412	1.09509764752885	0.488070267615623	0.89634623671012
GO:0052866	phosphatidylinositol phosphate phosphatase activity	5/2503	34/18639	0.147058823529412	1.09509764752885	0.488070267615623	0.89634623671012
GO:0003720	telomerase activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0003995	acyl-CoA dehydrogenase activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0004000	adenosine deaminase activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0004300	enoyl-CoA hydratase activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0005049	nuclear export signal receptor activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0005165	neurotrophin receptor binding	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0008504	monoamine transmembrane transporter activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0015166	polyol transmembrane transporter activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0016273	arginine N-methyltransferase activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0016274	protein-arginine N-methyltransferase activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0140900	chloride:bicarbonate antiporter activity	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:1990459	transferrin receptor binding	2/2503	12/18639	0.166666666666667	1.24111066719936	0.492990430190566	0.89634623671012
GO:0005385	zinc ion transmembrane transporter activity	4/2503	27/18639	0.148148148148148	1.10320948195499	0.499869071601877	0.906783091275688
GO:0042562	hormone binding	13/2503	94/18639	0.138297872340426	1.02985778767607	0.500125751111283	0.906783091275688
GO:0004520	DNA endonuclease activity	6/2503	42/18639	0.142857142857143	1.06380914331374	0.502830651816723	0.909151387151237
GO:0019894	kinesin binding	6/2503	42/18639	0.142857142857143	1.06380914331374	0.502830651816723	0.909151387151237
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2503	57/18639	0.140350877192982	1.04514582500999	0.504813996139043	0.910205540888705
GO:0016504	peptidase activator activity	8/2503	57/18639	0.140350877192982	1.04514582500999	0.504813996139043	0.910205540888705
GO:0061631	ubiquitin conjugating enzyme activity	5/2503	35/18639	0.142857142857143	1.06380914331374	0.514868361471169	0.923669716599671
GO:0015605	organophosphate ester transmembrane transporter activity	7/2503	50/18639	0.14	1.04253296044746	0.515036475420647	0.923669716599671
GO:0001972	retinoic acid binding	3/2503	20/18639	0.15	1.11699960047942	0.515134194275914	0.923669716599671
GO:0016505	peptidase activator activity involved in apoptotic process	3/2503	20/18639	0.15	1.11699960047942	0.515134194275914	0.923669716599671
GO:0048306	calcium-dependent protein binding	11/2503	80/18639	0.1375	1.02391630043947	0.515834010962585	0.923669716599671
GO:0001664	G protein-coupled receptor binding	40/2503	297/18639	0.134680134680135	1.00291771086817	0.518161375359561	0.926470569820159
GO:0141108	transporter regulator activity	23/2503	170/18639	0.135294117647059	1.00748983572654	0.518823519099289	0.926470569820159
GO:0051959	dynein light intermediate chain binding	4/2503	28/18639	0.142857142857143	1.06380914331374	0.529762501135292	0.935346103422391
GO:0015276	ligand-gated monoatomic ion channel activity	25/2503	186/18639	0.134408602150538	1.00089569935432	0.530858034461425	0.935346103422391
GO:0005010	insulin-like growth factor receptor activity	7/2503	51/18639	0.137254901960784	1.02209113769359	0.537037284439911	0.935346103422391
GO:0003964	RNA-directed DNA polymerase activity	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0005172	vascular endothelial growth factor receptor binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0008035	high-density lipoprotein particle binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0019855	calcium channel inhibitor activity	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0031432	titin binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0031994	insulin-like growth factor I binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0035325	Toll-like receptor binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0043560	insulin receptor substrate binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0045159	myosin II binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0071837	HMG box domain binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0089720	caspase binding	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0140333	glycerophospholipid flippase activity	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/2503	13/18639	0.153846153846154	1.14564061587633	0.537303050808142	0.935346103422391
GO:0004190	aspartic-type endopeptidase activity	5/2503	36/18639	0.138888888888889	1.0342588893328	0.541061745979721	0.935346103422391
GO:0005484	SNAP receptor activity	5/2503	36/18639	0.138888888888889	1.0342588893328	0.541061745979721	0.935346103422391
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/2503	36/18639	0.138888888888889	1.0342588893328	0.541061745979721	0.935346103422391
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2503	36/18639	0.138888888888889	1.0342588893328	0.541061745979721	0.935346103422391
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2503	36/18639	0.138888888888889	1.0342588893328	0.541061745979721	0.935346103422391
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2503	36/18639	0.138888888888889	1.0342588893328	0.541061745979721	0.935346103422391
GO:0008201	heparin binding	23/2503	172/18639	0.133720930232558	0.995774837636696	0.54282025621944	0.937139884575394
GO:0070888	E-box binding	8/2503	59/18639	0.135593220338983	1.00971715297575	0.545887077159936	0.941184615792993
GO:0036122	BMP binding	3/2503	21/18639	0.142857142857143	1.06380914331374	0.549477495443938	0.944868709096718
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	3/2503	21/18639	0.142857142857143	1.06380914331374	0.549477495443938	0.944868709096718
GO:0022834	ligand-gated channel activity	25/2503	188/18639	0.132978723404255	0.990247872765447	0.553731059088482	0.948513103802131
GO:0008173	RNA methyltransferase activity	9/2503	67/18639	0.134328358208955	1.00029814968307	0.553785727527552	0.948513103802131
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	9/2503	67/18639	0.134328358208955	1.00029814968307	0.553785727527552	0.948513103802131
GO:0030159	signaling receptor complex adaptor activity	7/2503	52/18639	0.134615384615385	1.00243553889179	0.558623359034797	0.950748389032502
GO:0003785	actin monomer binding	4/2503	29/18639	0.137931034482759	1.02712606940637	0.558747514785255	0.950748389032502
GO:0004181	metallocarboxypeptidase activity	4/2503	29/18639	0.137931034482759	1.02712606940637	0.558747514785255	0.950748389032502
GO:0005416	amino acid:monoatomic cation symporter activity	4/2503	29/18639	0.137931034482759	1.02712606940637	0.558747514785255	0.950748389032502
GO:0051861	glycolipid binding	4/2503	29/18639	0.137931034482759	1.02712606940637	0.558747514785255	0.950748389032502
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/2503	60/18639	0.133333333333333	0.992888533759488	0.565902120916532	0.957326161813278
GO:0022829	wide pore channel activity	5/2503	37/18639	0.135135135135135	1.00630594637786	0.566572417091854	0.957326161813278
GO:0030551	cyclic nucleotide binding	5/2503	37/18639	0.135135135135135	1.00630594637786	0.566572417091854	0.957326161813278
GO:0043394	proteoglycan binding	5/2503	37/18639	0.135135135135135	1.00630594637786	0.566572417091854	0.957326161813278
GO:0070001	aspartic-type peptidase activity	5/2503	37/18639	0.135135135135135	1.00630594637786	0.566572417091854	0.957326161813278
GO:0051082	unfolded protein binding	16/2503	121/18639	0.132231404958678	0.98468284339784	0.567031649689403	0.957326161813278
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	9/2503	68/18639	0.132352941176471	0.985587882775963	0.57251645129729	0.964082107106836
GO:0032934	sterol binding	9/2503	68/18639	0.132352941176471	0.985587882775963	0.57251645129729	0.964082107106836
GO:0042605	peptide antigen binding	6/2503	45/18639	0.133333333333333	0.992888533759488	0.573484587041741	0.964382858585242
GO:0015926	glucosidase activity	2/2503	14/18639	0.142857142857143	1.06380914331374	0.578862488766548	0.964382858585242
GO:0019763	immunoglobulin receptor activity	2/2503	14/18639	0.142857142857143	1.06380914331374	0.578862488766548	0.964382858585242
GO:1990825	sequence-specific mRNA binding	2/2503	14/18639	0.142857142857143	1.06380914331374	0.578862488766548	0.964382858585242
GO:0017046	peptide hormone binding	7/2503	53/18639	0.132075471698113	0.983521660799493	0.579748174377834	0.964382858585242
GO:0099106	ion channel regulator activity	21/2503	160/18639	0.13125	0.977374650419497	0.58033369440243	0.964382858585242
GO:0005243	gap junction channel activity	3/2503	22/18639	0.136363636363636	1.01545418225402	0.582338879991858	0.964382858585242
GO:0008093	cytoskeletal anchor activity	3/2503	22/18639	0.136363636363636	1.01545418225402	0.582338879991858	0.964382858585242
GO:0008649	rRNA methyltransferase activity	3/2503	22/18639	0.136363636363636	1.01545418225402	0.582338879991858	0.964382858585242
GO:0008970	phospholipase A1 activity	3/2503	22/18639	0.136363636363636	1.01545418225402	0.582338879991858	0.964382858585242
GO:0015377	chloride:monoatomic cation symporter activity	3/2503	22/18639	0.136363636363636	1.01545418225402	0.582338879991858	0.964382858585242
GO:0061133	endopeptidase activator activity	3/2503	22/18639	0.136363636363636	1.01545418225402	0.582338879991858	0.964382858585242
GO:0140035	ubiquitin-like protein reader activity	3/2503	22/18639	0.136363636363636	1.01545418225402	0.582338879991858	0.964382858585242
GO:0016247	channel regulator activity	22/2503	168/18639	0.130952380952381	0.975158381370926	0.585103672185731	0.967728719900064
GO:0016298	lipase activity	17/2503	130/18639	0.130769230769231	0.973794523494883	0.586054810129047	0.967964938875296
GO:0001965	G-protein alpha-subunit binding	4/2503	30/18639	0.133333333333333	0.992888533759488	0.586735670641333	0.967964938875296
GO:0042887	amide transmembrane transporter activity	5/2503	38/18639	0.131578947368421	0.979824210946864	0.591334307082213	0.974227897793376
GO:0005126	cytokine receptor binding	36/2503	275/18639	0.130909090909091	0.974836014963862	0.592780205503508	0.974227897793376
GO:1901681	sulfur compound binding	36/2503	275/18639	0.130909090909091	0.974836014963862	0.592780205503508	0.974227897793376
GO:0004180	carboxypeptidase activity	6/2503	46/18639	0.130434782608696	0.971304000416891	0.595906177843599	0.978128827268534
GO:0015485	cholesterol binding	7/2503	54/18639	0.12962962962963	0.965308296710614	0.600370661653868	0.984214199432571
GO:0005267	potassium channel activity	16/2503	124/18639	0.129032258064516	0.96085987138015	0.608267183083828	0.992569638867664
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/2503	23/18639	0.130434782608696	0.971304000416891	0.613632301500947	0.992569638867664
GO:0043274	phospholipase binding	3/2503	23/18639	0.130434782608696	0.971304000416891	0.613632301500947	0.992569638867664
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/2503	23/18639	0.130434782608696	0.971304000416891	0.613632301500947	0.992569638867664
GO:0140102	catalytic activity, acting on a rRNA	3/2503	23/18639	0.130434782608696	0.971304000416891	0.613632301500947	0.992569638867664
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/2503	23/18639	0.130434782608696	0.971304000416891	0.613632301500947	0.992569638867664
GO:0047499	calcium-independent phospholipase A2 activity	4/2503	31/18639	0.129032258064516	0.96085987138015	0.61365748212093	0.992569638867664
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	5/2503	39/18639	0.128205128205128	0.954700513230277	0.615292770971822	0.992569638867664
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2503	15/18639	0.133333333333333	0.992888533759488	0.61760884410771	0.992569638867664
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/2503	15/18639	0.133333333333333	0.992888533759488	0.61760884410771	0.992569638867664
GO:0030553	cGMP binding	2/2503	15/18639	0.133333333333333	0.992888533759488	0.61760884410771	0.992569638867664
GO:0034483	heparan sulfate sulfotransferase activity	2/2503	15/18639	0.133333333333333	0.992888533759488	0.61760884410771	0.992569638867664
GO:0050700	CARD domain binding	2/2503	15/18639	0.133333333333333	0.992888533759488	0.61760884410771	0.992569638867664
GO:0061578	K63-linked deubiquitinase activity	2/2503	15/18639	0.133333333333333	0.992888533759488	0.61760884410771	0.992569638867664
GO:0140161	monocarboxylate:sodium symporter activity	2/2503	15/18639	0.133333333333333	0.992888533759488	0.61760884410771	0.992569638867664
GO:0140359	ABC-type transporter activity	6/2503	47/18639	0.127659574468085	0.95063795785483	0.617683721418415	0.992569638867664
GO:0140313	molecular sequestering activity	7/2503	55/18639	0.127272727272727	0.947757236770421	0.620455116725546	0.995792162645938
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/2503	40/18639	0.125	0.930833000399521	0.638403966419546	1
GO:0140662	ATP-dependent protein folding chaperone	5/2503	40/18639	0.125	0.930833000399521	0.638403966419546	1
GO:0038187	pattern recognition receptor activity	6/2503	48/18639	0.125	0.930833000399521	0.638780800423624	1
GO:0015106	bicarbonate transmembrane transporter activity	4/2503	32/18639	0.125	0.930833000399521	0.639460875620786	1
GO:0022884	macromolecule transmembrane transporter activity	4/2503	32/18639	0.125	0.930833000399521	0.639460875620786	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/2503	32/18639	0.125	0.930833000399521	0.639460875620786	1
GO:0004536	DNA nuclease activity	8/2503	64/18639	0.125	0.930833000399521	0.641651410290246	1
GO:0050699	WW domain binding	3/2503	24/18639	0.125	0.930833000399521	0.643303321729146	1
GO:0000049	tRNA binding	10/2503	80/18639	0.125	0.930833000399521	0.64581958345686	1
GO:0004519	endonuclease activity	16/2503	127/18639	0.125984251968504	0.938162394103454	0.64765441826613	1
GO:0003688	DNA replication origin binding	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0008142	oxysterol binding	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0015378	sodium:chloride symporter activity	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0017070	U6 snRNA binding	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0022858	alanine transmembrane transporter activity	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0043023	ribosomal large subunit binding	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0140327	flippase activity	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0140328	floppase activity	2/2503	16/18639	0.125	0.930833000399521	0.653547925429366	1
GO:0004601	peroxidase activity	7/2503	57/18639	0.12280701754386	0.914502596883739	0.658893047719699	1
GO:0005249	voltage-gated potassium channel activity	12/2503	98/18639	0.122448979591837	0.911836408554632	0.679047090077913	1
GO:0016859	cis-trans isomerase activity	5/2503	42/18639	0.119047619047619	0.886507619428115	0.681958953286031	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0004549	tRNA-specific ribonuclease activity	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0032977	membrane insertase activity	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0045236	CXCR chemokine receptor binding	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0070402	NADPH binding	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0070492	oligosaccharide binding	2/2503	17/18639	0.117647058823529	0.876078118023078	0.68673469413861	1
GO:0019825	oxygen binding	4/2503	34/18639	0.117647058823529	0.876078118023078	0.687581486576182	1
GO:0035401	histone H3Y41 kinase activity	14/2503	115/18639	0.121739130434783	0.906550400389098	0.694497163969845	1
GO:0140801	histone H2AXY142 kinase activity	14/2503	115/18639	0.121739130434783	0.906550400389098	0.694497163969845	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/2503	59/18639	0.11864406779661	0.883502508853782	0.694877266662159	1
GO:0097602	cullin family protein binding	3/2503	26/18639	0.115384615384615	0.85923046190725	0.697691830882202	1
GO:0120014	phospholipid transfer activity	3/2503	26/18639	0.115384615384615	0.85923046190725	0.697691830882202	1
GO:0005021	vascular endothelial growth factor receptor activity	6/2503	51/18639	0.117647058823529	0.876078118023078	0.697726893799033	1
GO:0005030	neurotrophin receptor activity	6/2503	51/18639	0.117647058823529	0.876078118023078	0.697726893799033	1
GO:0016830	carbon-carbon lyase activity	6/2503	51/18639	0.117647058823529	0.876078118023078	0.697726893799033	1
GO:0046873	metal ion transmembrane transporter activity	57/2503	450/18639	0.126666666666667	0.943244107071514	0.704890012353852	1
GO:0005496	steroid binding	13/2503	108/18639	0.12037037037037	0.896357704088427	0.706435199212773	1
GO:0008234	cysteine-type peptidase activity	23/2503	187/18639	0.122994652406417	0.915899850660491	0.707127665974946	1
GO:0004623	phospholipase A2 activity	4/2503	35/18639	0.114285714285714	0.85104731465099	0.709867051105862	1
GO:0005343	organic acid:sodium symporter activity	4/2503	35/18639	0.114285714285714	0.85104731465099	0.709867051105862	1
GO:0043015	gamma-tubulin binding	4/2503	35/18639	0.114285714285714	0.85104731465099	0.709867051105862	1
GO:0015280	ligand-gated sodium channel activity	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0015373	monoatomic anion:sodium symporter activity	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0016854	racemase and epimerase activity	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0017128	phospholipid scramblase activity	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0022851	GABA-gated chloride ion channel activity	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0050811	GABA receptor binding	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2503	18/18639	0.111111111111111	0.82740711146624	0.717259967579128	1
GO:0043014	alpha-tubulin binding	5/2503	44/18639	0.113636363636364	0.846211818545019	0.721836889993349	1
GO:0004364	glutathione transferase activity	3/2503	27/18639	0.111111111111111	0.82740711146624	0.722419675792243	1
GO:0008320	protein transmembrane transporter activity	3/2503	27/18639	0.111111111111111	0.82740711146624	0.722419675792243	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/2503	27/18639	0.111111111111111	0.82740711146624	0.722419675792243	1
GO:0015103	inorganic anion transmembrane transporter activity	20/2503	165/18639	0.121212121212121	0.902625939781353	0.72300869149469	1
GO:0016409	palmitoyltransferase activity	4/2503	36/18639	0.111111111111111	0.82740711146624	0.730967714246629	1
GO:0045505	dynein intermediate chain binding	4/2503	36/18639	0.111111111111111	0.82740711146624	0.730967714246629	1
GO:0004222	metalloendopeptidase activity	13/2503	110/18639	0.118181818181818	0.880060291286819	0.731190522114734	1
GO:0038064	collagen receptor activity	6/2503	53/18639	0.113207547169811	0.843018566399566	0.7332481938061	1
GO:0016209	antioxidant activity	10/2503	86/18639	0.116279069767442	0.865891163162345	0.734488341324678	1
GO:0004715	non-membrane spanning protein tyrosine kinase activity	5/2503	45/18639	0.111111111111111	0.82740711146624	0.740380927862299	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0004890	GABA-A receptor activity	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0042577	lipid phosphatase activity	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0043395	heparan sulfate proteoglycan binding	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0097001	ceramide binding	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0120227	acyl-CoA binding	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0141147	intracellularly calcium-gated channel activity	2/2503	19/18639	0.105263157894737	0.783859368757491	0.745239804832769	1
GO:0003730	mRNA 3'-UTR binding	32/2503	262/18639	0.122137404580153	0.909516214130829	0.745421748880639	1
GO:0051537	2 iron, 2 sulfur cluster binding	3/2503	28/18639	0.107142857142857	0.797856857485303	0.745538536751077	1
GO:0004867	serine-type endopeptidase inhibitor activity	11/2503	95/18639	0.115789473684211	0.86224530563324	0.74564208194524	1
GO:0016779	nucleotidyltransferase activity	16/2503	136/18639	0.117647058823529	0.876078118023078	0.752242638444769	1
GO:0016829	lyase activity	24/2503	200/18639	0.12	0.89359968038354	0.754029206851303	1
GO:0004382	GDP phosphatase activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0004935	adrenergic receptor activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0004955	prostaglandin receptor activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0005528	FK506 binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0008519	ammonium channel activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0015203	polyamine transmembrane transporter activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0016868	intramolecular phosphotransferase activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0019911	structural constituent of myelin sheath	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0031419	cobalamin binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0031996	thioesterase binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0032356	oxidized DNA binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0033204	ribonuclease P RNA binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0042166	acetylcholine binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0050815	phosphoserine residue binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0051378	serotonin binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0051864	histone H3K36 demethylase activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0070513	death domain binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0071723	lipopeptide binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0097177	mitochondrial ribosome binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:1990763	arrestin family protein binding	1/2503	10/18639	0.1	0.744666400319617	0.763642131550844	1
GO:0001614	purinergic nucleotide receptor activity	2/2503	20/18639	0.1	0.744666400319617	0.770807094894642	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/2503	20/18639	0.1	0.744666400319617	0.770807094894642	1
GO:0016502	nucleotide receptor activity	2/2503	20/18639	0.1	0.744666400319617	0.770807094894642	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/2503	20/18639	0.1	0.744666400319617	0.770807094894642	1
GO:0015085	calcium ion transmembrane transporter activity	17/2503	147/18639	0.115646258503401	0.861178830301597	0.781083631741646	1
GO:0004521	RNA endonuclease activity	8/2503	73/18639	0.10958904109589	0.816072767473552	0.781250560957165	1
GO:0005262	calcium channel activity	15/2503	131/18639	0.114503816793893	0.852671450747652	0.783391711073568	1
GO:0001968	fibronectin binding	3/2503	30/18639	0.1	0.744666400319617	0.787130866570855	1
GO:0031624	ubiquitin conjugating enzyme binding	3/2503	30/18639	0.1	0.744666400319617	0.787130866570855	1
GO:0048019	receptor antagonist activity	3/2503	30/18639	0.1	0.744666400319617	0.787130866570855	1
GO:0001846	opsonin binding	2/2503	21/18639	0.0952380952380952	0.709206095542492	0.7941049474684	1
GO:0061891	calcium ion sensor activity	2/2503	21/18639	0.0952380952380952	0.709206095542492	0.7941049474684	1
GO:1904047	S-adenosyl-L-methionine binding	2/2503	21/18639	0.0952380952380952	0.709206095542492	0.7941049474684	1
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0003953	NAD+ nucleosidase activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0032404	mismatch repair complex binding	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0034511	U3 snoRNA binding	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0035252	UDP-xylosyltransferase activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0042285	xylosyltransferase activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0070697	activin receptor binding	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0140537	transcription regulator activator activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0180030	inositol phosphate kinase activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:1990948	ubiquitin ligase inhibitor activity	1/2503	11/18639	0.0909090909090909	0.676969454836015	0.795399270674159	1
GO:0005261	monoatomic cation channel activity	41/2503	341/18639	0.120234604105572	0.895346698331504	0.800442707665522	1
GO:0001540	amyloid-beta binding	9/2503	83/18639	0.108433734939759	0.807469590708018	0.800529891348218	1
GO:0022836	gated channel activity	38/2503	318/18639	0.119496855345912	0.889852931199542	0.804673694825801	1
GO:0005004	GPI-linked ephrin receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0005008	hepatocyte growth factor receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0005009	insulin receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0005011	macrophage colony-stimulating factor receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0005020	stem cell factor receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0008288	boss receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0016763	pentosyltransferase activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0036332	placental growth factor receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0038062	protein tyrosine kinase collagen receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0060175	brain-derived neurotrophic factor receptor activity	5/2503	49/18639	0.102040816326531	0.759863673795527	0.805434263900288	1
GO:0044183	protein folding chaperone	8/2503	75/18639	0.106666666666667	0.794310827007591	0.806063519965264	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	6/2503	58/18639	0.103448275862069	0.770344552054776	0.808739375468499	1
GO:0022832	voltage-gated channel activity	20/2503	175/18639	0.114285714285714	0.85104731465099	0.812205690760912	1
GO:0140784	metal ion sensor activity	2/2503	22/18639	0.0909090909090909	0.676969454836015	0.815281554216054	1
GO:0022843	voltage-gated monoatomic cation channel activity	16/2503	143/18639	0.111888111888112	0.833193175182788	0.817903475819381	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/2503	41/18639	0.0975609756097561	0.72650380518987	0.8193370724077	1
GO:0017080	sodium channel regulator activity	4/2503	41/18639	0.0975609756097561	0.72650380518987	0.8193370724077	1
GO:0005006	epidermal growth factor receptor activity	5/2503	50/18639	0.1	0.744666400319617	0.819502267236495	1
GO:0005007	fibroblast growth factor receptor activity	5/2503	50/18639	0.1	0.744666400319617	0.819502267236495	1
GO:0005017	platelet-derived growth factor receptor activity	5/2503	50/18639	0.1	0.744666400319617	0.819502267236495	1
GO:0005019	platelet-derived growth factor beta-receptor activity	5/2503	50/18639	0.1	0.744666400319617	0.819502267236495	1
GO:0048020	CCR chemokine receptor binding	5/2503	50/18639	0.1	0.744666400319617	0.819502267236495	1
GO:0015079	potassium ion transmembrane transporter activity	18/2503	160/18639	0.1125	0.837749700359569	0.822527362974604	1
GO:0004526	ribonuclease P activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0004875	complement receptor activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0005078	MAP-kinase scaffold activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0005527	macrolide binding	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0010853	cyclase activator activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0015132	prostaglandin transmembrane transporter activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0015269	calcium-activated potassium channel activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0016423	tRNA (guanine) methyltransferase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0016801	hydrolase activity, acting on ether bonds	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0016803	ether hydrolase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0016840	carbon-nitrogen lyase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0035251	UDP-glucosyltransferase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0042301	phosphate ion binding	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0097371	MDM2/MDM4 family protein binding	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:1990817	poly(A) RNA polymerase activity	1/2503	12/18639	0.0833333333333333	0.62055533359968	0.822890983445395	1
GO:0030515	snoRNA binding	3/2503	32/18639	0.09375	0.69812475029964	0.822916241136124	1
GO:0042910	xenobiotic transmembrane transporter activity	3/2503	32/18639	0.09375	0.69812475029964	0.822916241136124	1
GO:0005548	phospholipid transporter activity	7/2503	68/18639	0.102941176470588	0.766568353270193	0.824846135379984	1
GO:0016493	C-C chemokine receptor activity	2/2503	23/18639	0.0869565217391304	0.647536000277927	0.834486244950826	1
GO:0005200	structural constituent of cytoskeleton	12/2503	112/18639	0.107142857142857	0.797856857485303	0.837556912567511	1
GO:0030296	protein tyrosine kinase activator activity	3/2503	33/18639	0.0909090909090909	0.676969454836015	0.838796907403419	1
GO:0140311	protein sequestering activity	3/2503	33/18639	0.0909090909090909	0.676969454836015	0.838796907403419	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	6/2503	61/18639	0.0983606557377049	0.732458754412738	0.845332008971281	1
GO:0004896	cytokine receptor activity	10/2503	96/18639	0.104166666666667	0.7756941669996	0.846435775504839	1
GO:0002161	aminoacyl-tRNA editing activity	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0004465	lipoprotein lipase activity	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0004993	G protein-coupled serotonin receptor activity	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0005542	folic acid binding	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0008253	5'-nucleotidase activity	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0008417	fucosyltransferase activity	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0030955	potassium ion binding	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0032396	inhibitory MHC class I receptor activity	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0039706	co-receptor binding	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0070700	BMP receptor binding	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0071714	icosanoid transmembrane transporter activity	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:1901338	catecholamine binding	1/2503	13/18639	0.0769230769230769	0.572820307938167	0.846689977831833	1
GO:0015081	sodium ion transmembrane transporter activity	18/2503	164/18639	0.109756097560976	0.817316780838603	0.851799025383447	1
GO:0005540	hyaluronic acid binding	2/2503	24/18639	0.0833333333333333	0.62055533359968	0.851866510698252	1
GO:0019957	C-C chemokine binding	2/2503	24/18639	0.0833333333333333	0.62055533359968	0.851866510698252	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2503	24/18639	0.0833333333333333	0.62055533359968	0.851866510698252	1
GO:0140612	DNA damage sensor activity	2/2503	24/18639	0.0833333333333333	0.62055533359968	0.851866510698252	1
GO:0008175	tRNA methyltransferase activity	3/2503	34/18639	0.0882352941176471	0.657058588517309	0.853430657806054	1
GO:0008376	acetylgalactosaminyltransferase activity	3/2503	34/18639	0.0882352941176471	0.657058588517309	0.853430657806054	1
GO:0015035	protein-disulfide reductase activity	3/2503	34/18639	0.0882352941176471	0.657058588517309	0.853430657806054	1
GO:0016831	carboxy-lyase activity	3/2503	34/18639	0.0882352941176471	0.657058588517309	0.853430657806054	1
GO:0090482	vitamin transmembrane transporter activity	3/2503	34/18639	0.0882352941176471	0.657058588517309	0.853430657806054	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	20/2503	181/18639	0.110497237569061	0.82283580145814	0.854757877132969	1
GO:0005244	voltage-gated monoatomic ion channel activity	19/2503	173/18639	0.109826589595376	0.817841711333683	0.856526012053242	1
GO:0005003	ephrin receptor activity	5/2503	53/18639	0.0943396226415094	0.702515471999638	0.856830150000123	1
GO:0005005	transmembrane-ephrin receptor activity	5/2503	53/18639	0.0943396226415094	0.702515471999638	0.856830150000123	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	5/2503	53/18639	0.0943396226415094	0.702515471999638	0.856830150000123	1
GO:0016860	intramolecular oxidoreductase activity	5/2503	53/18639	0.0943396226415094	0.702515471999638	0.856830150000123	1
GO:0016790	thiolester hydrolase activity	4/2503	44/18639	0.0909090909090909	0.676969454836015	0.859822637961793	1
GO:0008509	monoatomic anion transmembrane transporter activity	16/2503	149/18639	0.10738255033557	0.799641772155293	0.863240047566166	1
GO:0042379	chemokine receptor binding	7/2503	72/18639	0.0972222222222222	0.72398122253296	0.866559550600898	1
GO:0004705	JUN kinase activity	1/2503	14/18639	0.0714285714285714	0.531904571656869	0.867292092375316	1
GO:0008195	phosphatidate phosphatase activity	1/2503	14/18639	0.0714285714285714	0.531904571656869	0.867292092375316	1
GO:0016530	metallochaperone activity	1/2503	14/18639	0.0714285714285714	0.531904571656869	0.867292092375316	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2503	14/18639	0.0714285714285714	0.531904571656869	0.867292092375316	1
GO:0030983	mismatched DNA binding	1/2503	14/18639	0.0714285714285714	0.531904571656869	0.867292092375316	1
GO:0043176	amine binding	1/2503	14/18639	0.0714285714285714	0.531904571656869	0.867292092375316	1
GO:1901474	azole transmembrane transporter activity	1/2503	14/18639	0.0714285714285714	0.531904571656869	0.867292092375316	1
GO:0001848	complement binding	2/2503	25/18639	0.08	0.595733120255693	0.867565805222528	1
GO:0005251	delayed rectifier potassium channel activity	2/2503	25/18639	0.08	0.595733120255693	0.867565805222528	1
GO:0008483	transaminase activity	2/2503	25/18639	0.08	0.595733120255693	0.867565805222528	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/2503	25/18639	0.08	0.595733120255693	0.867565805222528	1
GO:0017056	structural constituent of nuclear pore	2/2503	25/18639	0.08	0.595733120255693	0.867565805222528	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2503	25/18639	0.08	0.595733120255693	0.867565805222528	1
GO:0019707	protein-cysteine S-acyltransferase activity	2/2503	25/18639	0.08	0.595733120255693	0.867565805222528	1
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	5/2503	54/18639	0.0925925925925926	0.689505926221867	0.867745687211857	1
GO:0050661	NADP binding	5/2503	54/18639	0.0925925925925926	0.689505926221867	0.867745687211857	1
GO:0008009	chemokine activity	4/2503	45/18639	0.0888888888888889	0.661925689172992	0.871475487727598	1
GO:0051539	4 iron, 4 sulfur cluster binding	4/2503	45/18639	0.0888888888888889	0.661925689172992	0.871475487727598	1
GO:0140303	intramembrane lipid transporter activity	4/2503	45/18639	0.0888888888888889	0.661925689172992	0.871475487727598	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	9/2503	91/18639	0.0989010989010989	0.736483253063357	0.877503336080434	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/2503	26/18639	0.0769230769230769	0.572820307938167	0.881721969750889	1
GO:0004529	DNA exonuclease activity	2/2503	26/18639	0.0769230769230769	0.572820307938167	0.881721969750889	1
GO:0004950	chemokine receptor activity	2/2503	26/18639	0.0769230769230769	0.572820307938167	0.881721969750889	1
GO:0019865	immunoglobulin binding	2/2503	26/18639	0.0769230769230769	0.572820307938167	0.881721969750889	1
GO:0160215	deacylase activity	6/2503	65/18639	0.0923076923076923	0.6873843695258	0.885035162551188	1
GO:0000774	adenyl-nucleotide exchange factor activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0008252	nucleotidase activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0010181	FMN binding	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0015250	water channel activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0015929	hexosaminidase activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0017081	chloride channel regulator activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0031386	protein tag activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0047372	monoacylglycerol lipase activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0140776	protein-containing complex destabilizing activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0141047	molecular tag activity	1/2503	15/18639	0.0666666666666667	0.496444266879744	0.885126610108717	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/2503	47/18639	0.0851063829787234	0.633758638569886	0.89229000784313	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0005104	fibroblast growth factor receptor binding	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0015252	proton channel activity	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0016405	CoA-ligase activity	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0023026	MHC class II protein complex binding	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0035255	ionotropic glutamate receptor binding	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/2503	27/18639	0.0740740740740741	0.551604740977494	0.89446615326758	1
GO:0033218	amide binding	27/2503	247/18639	0.109311740890688	0.814007806017395	0.897575150896861	1
GO:0000062	fatty-acyl-CoA binding	1/2503	16/18639	0.0625	0.46541650019976	0.90056518908734	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/2503	16/18639	0.0625	0.46541650019976	0.90056518908734	1
GO:0005149	interleukin-1 receptor binding	1/2503	16/18639	0.0625	0.46541650019976	0.90056518908734	1
GO:0008296	3'-5'-DNA exonuclease activity	1/2503	16/18639	0.0625	0.46541650019976	0.90056518908734	1
GO:0019841	retinol binding	1/2503	16/18639	0.0625	0.46541650019976	0.90056518908734	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/2503	16/18639	0.0625	0.46541650019976	0.90056518908734	1
GO:0005501	retinoid binding	3/2503	38/18639	0.0789473684210526	0.587894526568118	0.90093476837588	1
GO:0019840	isoprenoid binding	3/2503	38/18639	0.0789473684210526	0.587894526568118	0.90093476837588	1
GO:0015108	chloride transmembrane transporter activity	12/2503	121/18639	0.0991735537190083	0.73851213254838	0.902375533162227	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	13/2503	130/18639	0.1	0.744666400319617	0.903950351986675	1
GO:0016866	intramolecular transferase activity	2/2503	28/18639	0.0714285714285714	0.531904571656869	0.90592212376885	1
GO:0046625	sphingolipid binding	2/2503	28/18639	0.0714285714285714	0.531904571656869	0.90592212376885	1
GO:0050698	proteoglycan sulfotransferase activity	2/2503	28/18639	0.0714285714285714	0.531904571656869	0.90592212376885	1
GO:0003777	microtubule motor activity	6/2503	68/18639	0.0882352941176471	0.657058588517309	0.908826748610767	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0004550	nucleoside diphosphate kinase activity	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0004659	prenyltransferase activity	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0008569	minus-end-directed microtubule motor activity	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0016805	dipeptidase activity	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0017110	nucleoside diphosphate phosphatase activity	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0048038	quinone binding	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0070403	NAD+ binding	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:1901567	fatty acid derivative binding	1/2503	17/18639	0.0588235294117647	0.438039059011539	0.913929595021636	1
GO:0005216	monoatomic ion channel activity	51/2503	448/18639	0.113839285714286	0.847722911078135	0.914708648103224	1
GO:0016417	S-acyltransferase activity	2/2503	29/18639	0.0689655172413793	0.513563034703184	0.916205885012624	1
GO:0035250	UDP-galactosyltransferase activity	2/2503	29/18639	0.0689655172413793	0.513563034703184	0.916205885012624	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	8/2503	88/18639	0.0909090909090909	0.676969454836015	0.918348766358701	1
GO:0015036	disulfide oxidoreductase activity	3/2503	40/18639	0.075	0.558499800239712	0.919042760580374	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/2503	40/18639	0.075	0.558499800239712	0.919042760580374	1
GO:0071949	FAD binding	3/2503	40/18639	0.075	0.558499800239712	0.919042760580374	1
GO:0015370	solute:sodium symporter activity	7/2503	79/18639	0.0886075949367089	0.659830987624977	0.919769390038502	1
GO:0016835	carbon-oxygen lyase activity	7/2503	79/18639	0.0886075949367089	0.659830987624977	0.919769390038502	1
GO:0020037	heme binding	14/2503	142/18639	0.0985915492957746	0.734178141160185	0.920502980793206	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/2503	30/18639	0.0666666666666667	0.496444266879744	0.925425529187036	1
GO:0016769	transferase activity, transferring nitrogenous groups	2/2503	30/18639	0.0666666666666667	0.496444266879744	0.925425529187036	1
GO:0033612	receptor serine/threonine kinase binding	2/2503	30/18639	0.0666666666666667	0.496444266879744	0.925425529187036	1
GO:0070566	adenylyltransferase activity	2/2503	30/18639	0.0666666666666667	0.496444266879744	0.925425529187036	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/2503	18/18639	0.0555555555555556	0.41370355573312	0.925498396635901	1
GO:0004970	glutamate-gated receptor activity	1/2503	18/18639	0.0555555555555556	0.41370355573312	0.925498396635901	1
GO:0005372	water transmembrane transporter activity	1/2503	18/18639	0.0555555555555556	0.41370355573312	0.925498396635901	1
GO:0015172	acidic amino acid transmembrane transporter activity	1/2503	18/18639	0.0555555555555556	0.41370355573312	0.925498396635901	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2503	18/18639	0.0555555555555556	0.41370355573312	0.925498396635901	1
GO:0032393	MHC class I receptor activity	1/2503	18/18639	0.0555555555555556	0.41370355573312	0.925498396635901	1
GO:0046906	tetrapyrrole binding	15/2503	152/18639	0.0986842105263158	0.734868158210148	0.926034409534416	1
GO:0001530	lipopolysaccharide binding	3/2503	41/18639	0.0731707317073171	0.544877853892402	0.926914262278217	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/2503	41/18639	0.0731707317073171	0.544877853892402	0.926914262278217	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/2503	41/18639	0.0731707317073171	0.544877853892402	0.926914262278217	1
GO:0015297	antiporter activity	13/2503	135/18639	0.0962962962962963	0.717086163270742	0.928532351971192	1
GO:0016853	isomerase activity	18/2503	180/18639	0.1	0.744666400319617	0.93342488723646	1
GO:0005164	tumor necrosis factor receptor binding	2/2503	31/18639	0.0645161290322581	0.480429935690075	0.933681269088276	1
GO:0016878	acid-thiol ligase activity	2/2503	31/18639	0.0645161290322581	0.480429935690075	0.933681269088276	1
GO:0003756	protein disulfide isomerase activity	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0008574	plus-end-directed microtubule motor activity	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0016918	retinal binding	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0031420	alkali metal ion binding	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0034987	immunoglobulin receptor binding	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0046527	glucosyltransferase activity	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0099589	serotonin receptor activity	1/2503	19/18639	0.0526315789473684	0.391929684378745	0.935512762847186	1
GO:0022804	active transmembrane transporter activity	51/2503	457/18639	0.111597374179431	0.831028149153182	0.937354334035474	1
GO:0005507	copper ion binding	5/2503	63/18639	0.0793650793650794	0.591005079618743	0.937855634194335	1
GO:1901682	sulfur compound transmembrane transporter activity	5/2503	63/18639	0.0793650793650794	0.591005079618743	0.937855634194335	1
GO:0005246	calcium channel regulator activity	4/2503	53/18639	0.0754716981132075	0.562012377599711	0.938013093024249	1
GO:0005245	voltage-gated calcium channel activity	3/2503	43/18639	0.0697674418604651	0.519534697897407	0.940586950663615	1
GO:0008375	acetylglucosaminyltransferase activity	3/2503	43/18639	0.0697674418604651	0.519534697897407	0.940586950663615	1
GO:0005254	chloride channel activity	7/2503	83/18639	0.0843373493975904	0.628031903884014	0.941016865867136	1
GO:0008378	galactosyltransferase activity	2/2503	32/18639	0.0625	0.46541650019976	0.941065604285086	1
GO:0051287	NAD binding	4/2503	54/18639	0.0740740740740741	0.551604740977494	0.943634485489241	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/2503	20/18639	0.05	0.372333200159808	0.944181482213109	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2503	20/18639	0.05	0.372333200159808	0.944181482213109	1
GO:0015464	acetylcholine receptor activity	1/2503	20/18639	0.05	0.372333200159808	0.944181482213109	1
GO:0016408	C-acyltransferase activity	1/2503	20/18639	0.05	0.372333200159808	0.944181482213109	1
GO:0030627	pre-mRNA 5'-splice site binding	1/2503	20/18639	0.05	0.372333200159808	0.944181482213109	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/2503	20/18639	0.05	0.372333200159808	0.944181482213109	1
GO:0005253	monoatomic anion channel activity	9/2503	103/18639	0.087378640776699	0.650679378920053	0.946021554341933	1
GO:0003954	NADH dehydrogenase activity	3/2503	44/18639	0.0681818181818182	0.507727091127011	0.946496534519845	1
GO:0030547	signaling receptor inhibitor activity	3/2503	44/18639	0.0681818181818182	0.507727091127011	0.946496534519845	1
GO:0019239	deaminase activity	2/2503	33/18639	0.0606060606060606	0.451312969890677	0.947663584729064	1
GO:0120013	lipid transfer activity	5/2503	65/18639	0.0769230769230769	0.572820307938167	0.947934913705674	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	11/2503	122/18639	0.0901639344262295	0.671420524878343	0.948039348903321	1
GO:0016874	ligase activity	16/2503	167/18639	0.0958083832335329	0.713452838629573	0.948294947134162	1
GO:0019842	vitamin binding	14/2503	150/18639	0.0933333333333333	0.695021973631642	0.950772119134479	1
GO:0008373	sialyltransferase activity	1/2503	21/18639	0.0476190476190476	0.354603047771246	0.951685308950345	1
GO:0015125	bile acid transmembrane transporter activity	1/2503	21/18639	0.0476190476190476	0.354603047771246	0.951685308950345	1
GO:0015174	basic amino acid transmembrane transporter activity	1/2503	21/18639	0.0476190476190476	0.354603047771246	0.951685308950345	1
GO:0051428	peptide hormone receptor binding	1/2503	21/18639	0.0476190476190476	0.354603047771246	0.951685308950345	1
GO:0051536	iron-sulfur cluster binding	6/2503	76/18639	0.0789473684210526	0.587894526568118	0.952564969988484	1
GO:0030170	pyridoxal phosphate binding	4/2503	56/18639	0.0714285714285714	0.531904571656869	0.953502435869439	1
GO:0050660	flavin adenine dinucleotide binding	7/2503	86/18639	0.0813953488372093	0.606123814213641	0.953515015661713	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/2503	34/18639	0.0588235294117647	0.438039059011539	0.953553142661753	1
GO:0051540	metal cluster binding	6/2503	77/18639	0.0779220779220779	0.580259532716584	0.956428621382287	1
GO:0016500	protein-hormone receptor activity	5/2503	67/18639	0.0746268656716418	0.555721194268371	0.9565085779709	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/2503	46/18639	0.0652173913043478	0.485652000208445	0.956709074995046	1
GO:0070279	vitamin B6 binding	4/2503	57/18639	0.0701754385964912	0.522572912504994	0.957815486924856	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/2503	22/18639	0.0454545454545455	0.338484727418008	0.958180725842454	1
GO:0033691	sialic acid binding	1/2503	22/18639	0.0454545454545455	0.338484727418008	0.958180725842454	1
GO:0034062	5'-3' RNA polymerase activity	1/2503	22/18639	0.0454545454545455	0.338484727418008	0.958180725842454	1
GO:0097747	RNA polymerase activity	1/2503	22/18639	0.0454545454545455	0.338484727418008	0.958180725842454	1
GO:0015294	solute:monoatomic cation symporter activity	10/2503	116/18639	0.0862068965517241	0.64195379337898	0.958538745614635	1
GO:0005506	iron ion binding	14/2503	154/18639	0.0909090909090909	0.676969454836015	0.961726544432748	1
GO:0004175	endopeptidase activity	43/2503	405/18639	0.106172839506173	0.790633462067741	0.963417028244236	1
GO:0004033	aldo-keto reductase (NADPH) activity	2/2503	36/18639	0.0555555555555556	0.41370355573312	0.963485421234192	1
GO:0061134	peptidase regulator activity	22/2503	226/18639	0.0973451327433628	0.724896495886352	0.96351429419999	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2503	23/18639	0.0434782608695652	0.323768000138964	0.963803202246619	1
GO:0004602	glutathione peroxidase activity	1/2503	23/18639	0.0434782608695652	0.323768000138964	0.963803202246619	1
GO:0031681	G-protein beta-subunit binding	1/2503	23/18639	0.0434782608695652	0.323768000138964	0.963803202246619	1
GO:0140103	catalytic activity, acting on a glycoprotein	1/2503	23/18639	0.0434782608695652	0.323768000138964	0.963803202246619	1
GO:0140375	immune receptor activity	14/2503	156/18639	0.0897435897435897	0.668290359261194	0.966349583837762	1
GO:0023023	MHC protein complex binding	2/2503	37/18639	0.0540540540540541	0.402522378551144	0.967651933309469	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	4/2503	60/18639	0.0666666666666667	0.496444266879744	0.968631860030443	1
GO:0035254	glutamate receptor binding	3/2503	49/18639	0.0612244897959184	0.455918204277316	0.968657895557644	1
GO:0004806	triacylglycerol lipase activity	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0015149	hexose transmembrane transporter activity	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0015295	solute:proton symporter activity	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0055056	D-glucose transmembrane transporter activity	1/2503	24/18639	0.0416666666666667	0.31027766679984	0.968670014922635	1
GO:0015101	organic cation transmembrane transporter activity	6/2503	81/18639	0.0740740740740741	0.551604740977494	0.96918792392874	1
GO:0140767	enzyme-substrate adaptor activity	12/2503	139/18639	0.0863309352517986	0.642877467901827	0.969447343646412	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	11/2503	130/18639	0.0846153846153846	0.630102338731983	0.97021989174893	1
GO:0016836	hydro-lyase activity	4/2503	61/18639	0.0655737704918033	0.488305836275158	0.971619635869574	1
GO:0015171	amino acid transmembrane transporter activity	8/2503	102/18639	0.0784313725490196	0.584052078682052	0.971912348180965	1
GO:0015645	fatty acid ligase activity	1/2503	25/18639	0.04	0.297866560127847	0.972882690326806	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2503	25/18639	0.04	0.297866560127847	0.972882690326806	1
GO:0120020	cholesterol transfer activity	1/2503	25/18639	0.04	0.297866560127847	0.972882690326806	1
GO:0120515	fatty acid-CoA ligase activity	1/2503	25/18639	0.04	0.297866560127847	0.972882690326806	1
GO:0031406	carboxylic acid binding	17/2503	187/18639	0.0909090909090909	0.676969454836015	0.973412720143473	1
GO:0015179	L-amino acid transmembrane transporter activity	4/2503	62/18639	0.0645161290322581	0.480429935690075	0.974339266532799	1
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/2503	39/18639	0.0512820512820513	0.381880205292111	0.974653299194636	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/2503	39/18639	0.0512820512820513	0.381880205292111	0.974653299194636	1
GO:0043177	organic acid binding	17/2503	189/18639	0.0899470899470899	0.669805756901242	0.976527317124396	1
GO:0008066	glutamate receptor activity	1/2503	26/18639	0.0384615384615385	0.286410153969083	0.976529119149843	1
GO:0015145	monosaccharide transmembrane transporter activity	1/2503	26/18639	0.0384615384615385	0.286410153969083	0.976529119149843	1
GO:0051139	metal cation:proton antiporter activity	1/2503	26/18639	0.0384615384615385	0.286410153969083	0.976529119149843	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/2503	63/18639	0.0634920634920635	0.472804063694995	0.976812733132017	1
GO:0022835	transmitter-gated channel activity	4/2503	63/18639	0.0634920634920635	0.472804063694995	0.976812733132017	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/2503	52/18639	0.0576923076923077	0.429615230953625	0.977439206365506	1
GO:0015144	carbohydrate transmembrane transporter activity	2/2503	40/18639	0.05	0.372333200159808	0.977580169648018	1
GO:0008395	steroid hydroxylase activity	1/2503	27/18639	0.037037037037037	0.275802370488747	0.979685387068391	1
GO:0008146	sulfotransferase activity	3/2503	53/18639	0.0566037735849057	0.421509283199783	0.979804773165981	1
GO:0009055	electron transfer activity	9/2503	116/18639	0.0775862068965517	0.577758414041082	0.979916235020653	1
GO:0008227	G protein-coupled amine receptor activity	2/2503	41/18639	0.0487804878048781	0.363251902594935	0.980178421308007	1
GO:0140828	metal cation:monoatomic cation antiporter activity	2/2503	41/18639	0.0487804878048781	0.363251902594935	0.980178421308007	1
GO:0015293	symporter activity	12/2503	146/18639	0.0821917808219178	0.612054575605164	0.981412664271993	1
GO:0061135	endopeptidase regulator activity	16/2503	184/18639	0.0869565217391304	0.647536000277927	0.982046424948535	1
GO:0008527	taste receptor activity	1/2503	28/18639	0.0357142857142857	0.265952285828434	0.982417359783189	1
GO:0051119	sugar transmembrane transporter activity	1/2503	28/18639	0.0357142857142857	0.265952285828434	0.982417359783189	1
GO:0030527	structural constituent of chromatin	7/2503	98/18639	0.0714285714285714	0.531904571656869	0.983049238543011	1
GO:0140101	catalytic activity, acting on a tRNA	11/2503	139/18639	0.079136690647482	0.589304345576675	0.98468780447879	1
GO:0015291	secondary active transmembrane transporter activity	27/2503	287/18639	0.0940766550522648	0.700557240718803	0.985541839283914	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/2503	56/18639	0.0535714285714286	0.398928428742652	0.98556220697456	1
GO:0030414	peptidase inhibitor activity	14/2503	169/18639	0.0828402366863905	0.616883408548795	0.986052159895522	1
GO:0005125	cytokine activity	21/2503	234/18639	0.0897435897435897	0.668290359261194	0.986231086610361	1
GO:0098918	structural constituent of synapse	1/2503	30/18639	0.0333333333333333	0.248222133439872	0.986828832073594	1
GO:0004866	endopeptidase inhibitor activity	13/2503	161/18639	0.0807453416149068	0.601283428829504	0.987497604912064	1
GO:0005184	neuropeptide hormone activity	1/2503	31/18639	0.032258064516129	0.240214967845038	0.988600417506438	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	4/2503	70/18639	0.0571428571428571	0.425523657325495	0.988777054201213	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/2503	32/18639	0.03125	0.23270825009988	0.990133798578095	1
GO:0120015	sterol transfer activity	1/2503	32/18639	0.03125	0.23270825009988	0.990133798578095	1
GO:0160041	neuropeptide activity	1/2503	32/18639	0.03125	0.23270825009988	0.990133798578095	1
GO:0008236	serine-type peptidase activity	16/2503	194/18639	0.0824742268041237	0.614157855933704	0.990881578419323	1
GO:0008514	organic anion transmembrane transporter activity	24/2503	269/18639	0.0892193308550186	0.664386379467316	0.991389697873799	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/2503	33/18639	0.0303030303030303	0.225656484945338	0.991460992760877	1
GO:0042923	neuropeptide binding	1/2503	33/18639	0.0303030303030303	0.225656484945338	0.991460992760877	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/2503	48/18639	0.0416666666666667	0.31027766679984	0.991728464732828	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/2503	73/18639	0.0547945205479452	0.408036383736776	0.991841203851604	1
GO:0001653	peptide receptor activity	9/2503	128/18639	0.0703125	0.52359356272473	0.992539431554591	1
GO:0015020	glucuronosyltransferase activity	1/2503	34/18639	0.0294117647058824	0.21901952950577	0.992609715491154	1
GO:0051427	hormone receptor binding	1/2503	34/18639	0.0294117647058824	0.21901952950577	0.992609715491154	1
GO:0016758	hexosyltransferase activity	16/2503	197/18639	0.0812182741116751	0.60480519822913	0.992612897267092	1
GO:0005319	lipid transporter activity	14/2503	178/18639	0.0786516853932584	0.585692674408687	0.992725771951606	1
GO:0030594	neurotransmitter receptor activity	6/2503	97/18639	0.0618556701030928	0.460618391950278	0.992977217568665	1
GO:0017171	serine hydrolase activity	16/2503	198/18639	0.0808080808080808	0.601750626520902	0.993118559457969	1
GO:0016229	steroid dehydrogenase activity	1/2503	35/18639	0.0285714285714286	0.212761828662748	0.99360395801336	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/2503	36/18639	0.0277777777777778	0.20685177786656	0.994464487635621	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2503	36/18639	0.0277777777777778	0.20685177786656	0.994464487635621	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	9/2503	132/18639	0.0681818181818182	0.507727091127011	0.994713868102262	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/2503	122/18639	0.0655737704918033	0.488305836275158	0.994935239679348	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/2503	53/18639	0.0377358490566038	0.281006188799855	0.995616353634027	1
GO:0015078	proton transmembrane transporter activity	14/2503	185/18639	0.0756756756756757	0.563531329971602	0.995708002544193	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/2503	69/18639	0.0434782608695652	0.323768000138964	0.996787105186314	1
GO:0071855	neuropeptide receptor binding	1/2503	40/18639	0.025	0.186166600079904	0.996894671096519	1
GO:0170055	lipid transmembrane transporter activity	2/2503	56/18639	0.0357142857142857	0.265952285828434	0.997015787735225	1
GO:0016782	transferase activity, transferring sulphur-containing groups	3/2503	70/18639	0.0428571428571429	0.319142742994121	0.997145764185647	1
GO:0003735	structural constituent of ribosome	12/2503	175/18639	0.0685714285714286	0.510628388790594	0.998098305248184	1
GO:0008528	G protein-coupled peptide receptor activity	7/2503	122/18639	0.0573770491803279	0.427267606740764	0.998186312580099	1
GO:0004252	serine-type endopeptidase activity	12/2503	176/18639	0.0681818181818182	0.507727091127011	0.998251822385635	1
GO:0019205	nucleobase-containing compound kinase activity	1/2503	44/18639	0.0227272727272727	0.169242363709004	0.998258195966563	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/2503	46/18639	0.0217391304347826	0.161884000069482	0.998695562302078	1
GO:0052689	carboxylic ester hydrolase activity	4/2503	92/18639	0.0434782608695652	0.323768000138964	0.999008254025361	1
GO:0008188	neuropeptide receptor activity	1/2503	48/18639	0.0208333333333333	0.15513883339992	0.999023138806944	1
GO:0033293	monocarboxylic acid binding	3/2503	79/18639	0.0379746835443038	0.282784708982133	0.99903066742154	1
GO:0003823	antigen binding	11/2503	174/18639	0.0632183908045977	0.470766115144585	0.999164264041689	1
GO:0016757	glycosyltransferase activity	20/2503	267/18639	0.0749063670411985	0.557802547055892	0.999240845960472	1
GO:0016597	amino acid binding	1/2503	51/18639	0.0196078431372549	0.146013019670513	0.999366976441709	1
GO:0008194	UDP-glycosyltransferase activity	8/2503	145/18639	0.0551724137931034	0.410850427762547	0.999425691289914	1
GO:0046943	carboxylic acid transmembrane transporter activity	11/2503	188/18639	0.0585106382978723	0.435709064016797	0.99976740366146	1
GO:0005342	organic acid transmembrane transporter activity	11/2503	189/18639	0.0582010582010582	0.433403725053745	0.999788161373528	1
GO:0004497	monooxygenase activity	2/2503	106/18639	0.0188679245283019	0.140503094399928	0.999996148266285	1
GO:0005179	hormone activity	3/2503	132/18639	0.0227272727272727	0.169242363709004	0.999998827189586	1
GO:0045182	translation regulator activity	18/2503	356/18639	0.050561797752809	0.376516719262727	0.999999953535515	1
GO:0030371	translation repressor activity	11/2503	329/18639	0.033434650455927	0.248976608009598	0.999999999932291	1
GO:0004984	olfactory receptor activity	2/2503	419/18639	0.00477326968973747	0.0355449355761153	1	1