ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 77/2651 175/18639 0.44 3.09360995850622 1.01324266340203e-21 1.1956263428144e-18 GO:0043021 ribonucleoprotein complex binding 76/2651 177/18639 0.429378531073446 3.01893113567634 1.12337771877582e-20 6.62792854077732e-18 GO:0140098 catalytic activity, acting on RNA 120/2651 387/18639 0.310077519379845 2.18013386786908 1.14265195971562e-17 4.49443104154811e-15 GO:0009055 electron transfer activity 52/2651 116/18639 0.448275862068966 3.15179697966935 1.54292651177608e-15 4.55163320973943e-13 GO:0045296 cadherin binding 102/2651 334/18639 0.305389221556886 2.14717076597465 9.8908865150228e-15 2.33424921754538e-12 GO:0140101 catalytic activity, acting on a tRNA 56/2651 139/18639 0.402877697841727 2.83260558659824 3.68199078866123e-14 7.24124855103376e-12 GO:0019843 rRNA binding 33/2651 65/18639 0.507692307692308 3.56954995212257 3.11984980243909e-12 4.81004822971078e-10 GO:0030515 snoRNA binding 22/2651 32/18639 0.6875 4.83376556016598 3.26104964726154e-12 4.81004822971078e-10 GO:0043022 ribosome binding 45/2651 112/18639 0.401785714285714 2.82492792477232 1.3022074963927e-11 1.70733871749265e-09 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 33/2651 68/18639 0.485294117647059 3.41206980717598 1.54031870376688e-11 1.81757607044492e-09 GO:0051540 metal cluster binding 34/2651 77/18639 0.441558441558442 3.10456725469928 1.97249776124335e-10 2.11595214387923e-08 GO:0051536 iron-sulfur cluster binding 33/2651 76/18639 0.434210526315789 3.05290456431535 6.22075718946246e-10 5.8473791494994e-08 GO:0016874 ligase activity 55/2651 167/18639 0.329341317365269 2.31557631624717 6.44202787656713e-10 5.8473791494994e-08 GO:0015078 proton transmembrane transporter activity 58/2651 185/18639 0.313513513513514 2.20429210802655 1.85787753604999e-09 1.56592535181357e-07 GO:0003743 translation initiation factor activity 25/2651 51/18639 0.490196078431373 3.44653515876362 3.42910376881519e-09 2.69756163146795e-07 GO:0016853 isomerase activity 56/2651 180/18639 0.311111111111111 2.18740098076198 4.79976538491669e-09 3.53982697137606e-07 GO:0031491 nucleosome binding 31/2651 74/18639 0.418918918918919 2.94539031675961 5.88212403461057e-09 4.08288609461204e-07 GO:0004812 aminoacyl-tRNA ligase activity 21/2651 41/18639 0.51219512195122 3.60120893174228 2.28480680254122e-08 1.41898527736771e-06 GO:0016875 ligase activity, forming carbon-oxygen bonds 21/2651 41/18639 0.51219512195122 3.60120893174228 2.28480680254122e-08 1.41898527736771e-06 GO:0003712 transcription coregulator activity 115/2651 495/18639 0.232323232323232 1.63344878433524 3.7218823208994e-08 2.03027784407105e-06 GO:0008135 translation factor activity, RNA binding 32/2651 83/18639 0.385542168674699 2.71072066462758 3.72309155515508e-08 2.03027784407105e-06 GO:0003697 single-stranded DNA binding 41/2651 121/18639 0.338842975206612 2.3823818237933 3.79703046943731e-08 2.03027784407105e-06 GO:0031492 nucleosomal DNA binding 21/2651 42/18639 0.5 3.51546586193889 3.95732122149441e-08 2.03027784407105e-06 GO:0180051 translation factor activity 32/2651 84/18639 0.380952380952381 2.67845018052487 5.19897001586555e-08 2.55616025780056e-06 GO:0003684 damaged DNA binding 29/2651 74/18639 0.391891891891892 2.75536513503318 1.05571038843463e-07 4.98295303341143e-06 GO:0003954 NADH dehydrogenase activity 21/2651 44/18639 0.477272727272727 3.35567195912349 1.10991695777851e-07 5.03731542376399e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 20/2651 41/18639 0.48780487804878 3.4297227921355 1.41074685903373e-07 6.16548627281408e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 39/2651 118/18639 0.330508474576271 2.32378251890876 1.71557829497289e-07 7.2299371002429e-06 GO:0000049 tRNA binding 30/2651 80/18639 0.375 2.63659939645417 2.02406945597891e-07 8.23586882087968e-06 GO:0016741 transferase activity, transferring one-carbon groups 59/2651 215/18639 0.274418604651163 1.92941847306414 2.7872688964462e-07 1.09632576593551e-05 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 49/2651 167/18639 0.293413173652695 2.06296799083839 3.21101483012855e-07 1.2222572579199e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 24/2651 58/18639 0.413793103448276 2.90935105815632 3.98479173068606e-07 1.46939195069049e-05 GO:0008168 methyltransferase activity 56/2651 204/18639 0.274509803921569 1.93005968890763 5.47484818561835e-07 1.95767298758474e-05 GO:0070182 DNA polymerase binding 13/2651 21/18639 0.619047619047619 4.35248154335291 6.27898433949643e-07 2.17917691782523e-05 GO:0051539 4 iron, 4 sulfur cluster binding 20/2651 45/18639 0.444444444444444 3.12485854394568 9.3674316584801e-07 3.15816267343043e-05 GO:0000287 magnesium ion binding 60/2651 230/18639 0.260869565217391 1.83415610188116 1.4194872880826e-06 4.65276388871518e-05 GO:0017069 snRNA binding 22/2651 54/18639 0.407407407407407 2.86445366528354 1.65361538118647e-06 5.27369229675686e-05 GO:0140104 molecular carrier activity 63/2651 249/18639 0.253012048192771 1.77891043616185 2.39750258840583e-06 7.44487645873389e-05 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 23/2651 60/18639 0.383333333333333 2.69519049415315 3.37425011005728e-06 9.90175885668382e-05 GO:0003995 acyl-CoA dehydrogenase activity 9/2651 12/18639 0.75 5.27319879290834 3.44044163664438e-06 9.90175885668382e-05 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 9/2651 12/18639 0.75 5.27319879290834 3.44044163664438e-06 9.90175885668382e-05 GO:0042393 histone binding 62/2651 247/18639 0.251012145748988 1.76484925862519 3.79514940975885e-06 0.000106625626274177 GO:0005525 GTP binding 86/2651 378/18639 0.227513227513228 1.59962996892457 4.6288850307521e-06 0.000127025217122965 GO:0140097 catalytic activity, acting on DNA 78/2651 336/18639 0.232142857142857 1.63218057875734 5.80077613194846e-06 0.000155566268993163 GO:0003713 transcription coactivator activity 63/2651 256/18639 0.24609375 1.73026835392305 6.3619272996777e-06 0.000166823871413771 GO:0051287 NAD binding 21/2651 54/18639 0.388888888888889 2.73425122595247 6.83933606433902e-06 0.000175443838172175 GO:0003727 single-stranded RNA binding 29/2651 89/18639 0.325842696629214 2.29097775272422 8.61319371654678e-06 0.000216246140117558 GO:0019104 DNA N-glycosylase activity 9/2651 13/18639 0.692307692307692 4.86756811653077 9.76057579503212e-06 0.00023994748829454 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 16/2651 36/18639 0.444444444444444 3.12485854394568 1.1486155021663e-05 0.000265758096579654 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 16/2651 36/18639 0.444444444444444 3.12485854394568 1.1486155021663e-05 0.000265758096579654 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 16/2651 36/18639 0.444444444444444 3.12485854394568 1.1486155021663e-05 0.000265758096579654 GO:0043023 ribosomal large subunit binding 10/2651 16/18639 0.625 4.39433232742361 1.17139803577933e-05 0.000265817246580695 GO:0140030 modification-dependent protein binding 46/2651 173/18639 0.265895953757225 1.86949629652242 1.34979463088881e-05 0.000300520314046943 GO:0019001 guanyl nucleotide binding 88/2651 400/18639 0.22 1.54680497925311 1.45156485126059e-05 0.000311426640815908 GO:0032561 guanyl ribonucleotide binding 88/2651 400/18639 0.22 1.54680497925311 1.45156485126059e-05 0.000311426640815908 GO:0061650 ubiquitin-like protein conjugating enzyme activity 17/2651 41/18639 0.414634146341463 2.91526437331518 1.89064362440282e-05 0.000398385620856309 GO:0003725 double-stranded RNA binding 25/2651 75/18639 0.333333333333333 2.34364390795926 2.27491313739188e-05 0.000470946930196916 GO:0016859 cis-trans isomerase activity 17/2651 42/18639 0.404761904761905 2.84585331680767 2.75726591591385e-05 0.000560960996685922 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 16/2651 39/18639 0.41025641025641 2.88448480979601 3.88220517426926e-05 0.000776441034853852 GO:0051537 2 iron, 2 sulfur cluster binding 13/2651 28/18639 0.464285714285714 3.26436115751468 4.34621465599092e-05 0.000854755549011547 GO:0003678 DNA helicase activity 24/2651 74/18639 0.324324324324324 2.28030218071712 5.45276684621136e-05 0.00105479752107039 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 21/2651 61/18639 0.344262295081967 2.42048469182678 5.88890212190128e-05 0.00112079104900702 GO:0140517 protein-RNA adaptor activity 11/2651 22/18639 0.5 3.51546586193889 7.28689093384838e-05 0.00136484623840335 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 35/2651 128/18639 0.2734375 1.92252039324783 7.49464183271114e-05 0.00138182458790612 GO:0017116 single-stranded DNA helicase activity 20/2651 58/18639 0.344827586206897 2.42445921513027 8.54249070212759e-05 0.00155079061977086 GO:0047429 nucleoside triphosphate diphosphatase activity 7/2651 10/18639 0.7 4.92165220671445 9.43647664753886e-05 0.00168712764304483 GO:0015399 primary active transmembrane transporter activity 42/2651 166/18639 0.253012048192771 1.77891043616185 0.000107789893795609 0.00189386615575199 GO:0009982 pseudouridine synthase activity 8/2651 13/18639 0.615384615384615 4.32672721469402 0.000109138049653504 0.00189386615575199 GO:0016835 carbon-oxygen lyase activity 24/2651 79/18639 0.30379746835443 2.13597925788692 0.000172669292672953 0.00295289515005919 GO:0031625 ubiquitin protein ligase binding 66/2651 302/18639 0.218543046357616 1.53656123766865 0.000197936796232289 0.00332866678348746 GO:0044183 protein folding chaperone 23/2651 75/18639 0.306666666666667 2.15615239532252 0.000200284187820008 0.00332866678348746 GO:0140297 DNA-binding transcription factor binding 98/2651 488/18639 0.200819672131148 1.41194940356562 0.000206850172890843 0.00339004450015548 GO:0016866 intramolecular transferase activity 12/2651 28/18639 0.428571428571429 3.01325645309048 0.000220349735703667 0.00356181764562092 GO:0015036 disulfide oxidoreductase activity 15/2651 40/18639 0.375 2.63659939645417 0.000224624067854702 0.00357932329402223 GO:0070990 snRNP binding 7/2651 11/18639 0.636363636363636 4.47422927883132 0.000227499361908193 0.00357932329402223 GO:0008276 protein methyltransferase activity 27/2651 95/18639 0.284210526315789 1.99826480573369 0.000240371059325166 0.00373207697373284 GO:0050660 flavin adenine dinucleotide binding 25/2651 86/18639 0.290697674418605 2.04387550112726 0.000274848182254697 0.00421195915663042 GO:0004540 RNA nuclease activity 32/2651 121/18639 0.264462809917355 1.85941996003379 0.000290185571561161 0.00433441739800215 GO:0051082 unfolded protein binding 32/2651 121/18639 0.264462809917355 1.85941996003379 0.000290185571561161 0.00433441739800215 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 18/2651 54/18639 0.333333333333333 2.34364390795926 0.00030867675361798 0.00455298211586521 GO:0070628 proteasome binding 9/2651 18/18639 0.5 3.51546586193889 0.000337576576697967 0.00491778222843952 GO:0016651 oxidoreductase activity, acting on NAD(P)H 25/2651 88/18639 0.284090909090909 1.99742378519255 0.000404724287418121 0.00582408120918759 GO:0061133 endopeptidase activator activity 10/2651 22/18639 0.454545454545455 3.19587805630808 0.000417382624316347 0.00586323210349155 GO:0070034 telomerase RNA binding 10/2651 22/18639 0.454545454545455 3.19587805630808 0.000417382624316347 0.00586323210349155 GO:0004386 helicase activity 38/2651 155/18639 0.245161290322581 1.72371229359584 0.000439668072134909 0.00599407311140805 GO:0001098 basal transcription machinery binding 19/2651 60/18639 0.316666666666667 2.2264617125613 0.000445506652163464 0.00599407311140805 GO:0001099 basal RNA polymerase II transcription machinery binding 19/2651 60/18639 0.316666666666667 2.2264617125613 0.000445506652163464 0.00599407311140805 GO:0044389 ubiquitin-like protein ligase binding 68/2651 322/18639 0.211180124223602 1.48479303485618 0.000447015621867719 0.00599407311140805 GO:0003714 transcription corepressor activity 47/2651 204/18639 0.230392156862745 1.6198715246189 0.000461819642811967 0.00612300200582158 GO:0015035 protein-disulfide reductase activity 13/2651 34/18639 0.382352941176471 2.68829742383562 0.000468558647638079 0.00614142177940379 GO:0016273 arginine N-methyltransferase activity 7/2651 12/18639 0.583333333333333 4.10137683892871 0.000478822715004363 0.00614142177940379 GO:0016274 protein-arginine N-methyltransferase activity 7/2651 12/18639 0.583333333333333 4.10137683892871 0.000478822715004363 0.00614142177940379 GO:0140102 catalytic activity, acting on a rRNA 10/2651 23/18639 0.434782608695652 3.0569268364686 0.000644798886148434 0.00806398707049356 GO:0016504 peptidase activator activity 18/2651 57/18639 0.315789473684211 2.22029422859298 0.000647651487573159 0.00806398707049356 GO:0061631 ubiquitin conjugating enzyme activity 13/2651 35/18639 0.371428571428571 2.61148892601175 0.00064921929804821 0.00806398707049356 GO:0003688 DNA replication origin binding 8/2651 16/18639 0.5 3.51546586193889 0.000731923567617936 0.00899656051863713 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 14/2651 40/18639 0.35 2.46082610335722 0.000812814680612141 0.00988784869198274 GO:0052689 carboxylic ester hydrolase activity 25/2651 92/18639 0.271739130434783 1.91057927279288 0.000833432156956228 0.0100352035225342 GO:0019903 protein phosphatase binding 35/2651 144/18639 0.243055555555556 1.70890701622029 0.000854613145229551 0.0101862980946553 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 9/2651 20/18639 0.45 3.163919275745 0.00089137391232698 0.0104140714509489 GO:0043024 ribosomal small subunit binding 9/2651 20/18639 0.45 3.163919275745 0.00089137391232698 0.0104140714509489 GO:0140597 protein carrier chaperone 43/2651 188/18639 0.228723404255319 1.60813863897205 0.000919355326823791 0.0106356792710988 GO:0031369 translation initiation factor binding 12/2651 32/18639 0.375 2.63659939645417 0.000943475854200794 0.0108087525044363 GO:0051219 phosphoprotein binding 25/2651 93/18639 0.268817204301075 1.89003540964456 0.000988357422563086 0.0112140553713889 GO:0016829 lyase activity 45/2651 200/18639 0.225 1.5819596378725 0.00101932647480304 0.0113561617597341 GO:0031593 polyubiquitin modification-dependent protein binding 18/2651 59/18639 0.305084745762712 2.14503001745424 0.00102012978519645 0.0113561617597341 GO:0001094 TFIID-class transcription factor complex binding 6/2651 10/18639 0.6 4.21855903432667 0.00103204506073539 0.0113814315109136 GO:0019902 phosphatase binding 43/2651 190/18639 0.226315789473684 1.59121086382497 0.0011510473747409 0.0125762583536506 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 18/2651 60/18639 0.3 2.10927951716333 0.00126639684221058 0.0137096171909035 GO:0019003 GDP binding 21/2651 75/18639 0.28 1.96866088268578 0.00139369751110615 0.0149505733009569 GO:0004518 nuclease activity 46/2651 209/18639 0.220095693779904 1.54747779568602 0.0014616663130334 0.0155384346790938 GO:0008474 palmitoyl-(protein) hydrolase activity 7/2651 14/18639 0.5 3.51546586193889 0.00159740364326828 0.0165345289390927 GO:0016530 metallochaperone activity 7/2651 14/18639 0.5 3.51546586193889 0.00159740364326828 0.0165345289390927 GO:0098599 palmitoyl hydrolase activity 7/2651 14/18639 0.5 3.51546586193889 0.00159740364326828 0.0165345289390927 GO:0003689 DNA clamp loader activity 37/2651 160/18639 0.23125 1.62590296114674 0.00163614771206146 0.0167882982628915 GO:0051087 protein-folding chaperone binding 32/2651 134/18639 0.238805970149254 1.6790284713738 0.00188971156716285 0.0192128911832135 GO:0016887 ATP hydrolysis activity 81/2651 417/18639 0.194244604316547 1.3657205506813 0.00190500700714914 0.0192128911832135 GO:0008173 RNA methyltransferase activity 19/2651 67/18639 0.283582089552239 1.99384630975639 0.00196272294340577 0.0193777486234458 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 6/2651 11/18639 0.545454545454545 3.8350536675697 0.00199749989932802 0.0193777486234458 GO:0034511 U3 snoRNA binding 6/2651 11/18639 0.545454545454545 3.8350536675697 0.00199749989932802 0.0193777486234458 GO:0008649 rRNA methyltransferase activity 9/2651 22/18639 0.409090909090909 2.87629025067727 0.00201988396668121 0.0193777486234458 GO:0034062 5'-3' RNA polymerase activity 9/2651 22/18639 0.409090909090909 2.87629025067727 0.00201988396668121 0.0193777486234458 GO:0097747 RNA polymerase activity 9/2651 22/18639 0.409090909090909 2.87629025067727 0.00201988396668121 0.0193777486234458 GO:0008408 3'-5' exonuclease activity 17/2651 58/18639 0.293103448275862 2.06079033286073 0.00225674201774571 0.0214754482333866 GO:0019205 nucleobase-containing compound kinase activity 14/2651 44/18639 0.318181818181818 2.23711463941566 0.00231520784630464 0.0218555620691158 GO:0032182 ubiquitin-like protein binding 29/2651 120/18639 0.241666666666667 1.69914183327046 0.0024869039293332 0.0232900526715331 GO:0031072 heat shock protein binding 31/2651 131/18639 0.236641221374046 1.66380827053596 0.00256248558825099 0.023591775962515 GO:0000774 adenyl-nucleotide exchange factor activity 7/2651 15/18639 0.466666666666667 3.28110147114297 0.00262940622716305 0.023591775962515 GO:0004129 cytochrome-c oxidase activity 7/2651 15/18639 0.466666666666667 3.28110147114297 0.00262940622716305 0.023591775962515 GO:0004177 aminopeptidase activity 13/2651 40/18639 0.325 2.28505281026028 0.00265823320547215 0.023591775962515 GO:0004532 RNA exonuclease activity 13/2651 40/18639 0.325 2.28505281026028 0.00265823320547215 0.023591775962515 GO:0140662 ATP-dependent protein folding chaperone 13/2651 40/18639 0.325 2.28505281026028 0.00265823320547215 0.023591775962515 GO:0003925 G protein activity 16/2651 54/18639 0.296296296296296 2.08323902929712 0.00265907305340211 0.023591775962515 GO:0004527 exonuclease activity 22/2651 84/18639 0.261904761904762 1.84143449911085 0.00275979501957088 0.0243026725604003 GO:0008094 ATP-dependent activity, acting on DNA 45/2651 210/18639 0.214285714285714 1.50662822654524 0.00283376973650055 0.0247692465857086 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 31/2651 132/18639 0.234848484848485 1.65120366242584 0.00290218729782368 0.025011411201685 GO:0008171 O-methyltransferase activity 9/2651 23/18639 0.391304347826087 2.75123415282174 0.002903867232738 0.025011411201685 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 29/2651 122/18639 0.237704918032787 1.67128704911849 0.0032245283285821 0.0275720538241078 GO:0016407 acetyltransferase activity 24/2651 96/18639 0.25 1.75773293096945 0.00352868998079175 0.0299557854484479 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 14/2651 46/18639 0.304347826086957 2.13984878552802 0.00366701177970497 0.0309076707146562 GO:0097718 disordered domain specific binding 10/2651 28/18639 0.357142857142857 2.51104704424207 0.00376746510502361 0.031529140595233 GO:0003924 GTPase activity 65/2651 331/18639 0.196374622356495 1.3806965620908 0.00387498430143118 0.0322005737724562 GO:0016836 hydro-lyase activity 17/2651 61/18639 0.278688524590164 1.95943998862168 0.00403649325306991 0.0330964999842665 GO:0001091 RNA polymerase II general transcription initiation factor binding 9/2651 24/18639 0.375 2.63659939645417 0.00406694279467682 0.0330964999842665 GO:0048027 mRNA 5'-UTR binding 9/2651 24/18639 0.375 2.63659939645417 0.00406694279467682 0.0330964999842665 GO:0016675 oxidoreductase activity, acting on a heme group of donors 7/2651 16/18639 0.4375 3.07603262919653 0.00410522607347592 0.0331792244294629 GO:0019787 ubiquitin-like protein transferase activity 89/2651 479/18639 0.18580375782881 1.30637353533429 0.00443152046349907 0.035572749298836 GO:1990518 single-stranded 3'-5' DNA helicase activity 14/2651 47/18639 0.297872340425532 2.09432008796359 0.00455132688515676 0.0362876062465201 GO:0140713 histone chaperone activity 36/2651 164/18639 0.219512195121951 1.54337525646098 0.00470497220110466 0.0372608536731778 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 12/2651 38/18639 0.315789473684211 2.22029422859298 0.00498498848899994 0.0389555391855625 GO:0043531 ADP binding 12/2651 38/18639 0.315789473684211 2.22029422859298 0.00498498848899994 0.0389555391855625 GO:0004521 RNA endonuclease activity 19/2651 73/18639 0.26027397260274 1.8299685308723 0.0055796378656534 0.0428889262434633 GO:0036121 double-stranded DNA helicase activity 14/2651 48/18639 0.291666666666667 2.05068841946435 0.00560037807866775 0.0428889262434633 GO:0043138 3'-5' DNA helicase activity 14/2651 48/18639 0.291666666666667 2.05068841946435 0.00560037807866775 0.0428889262434633 GO:0016860 intramolecular oxidoreductase activity 15/2651 53/18639 0.283018867924528 1.98988633694654 0.00573657258300603 0.0428889262434633 GO:0140296 general transcription initiation factor binding 15/2651 53/18639 0.283018867924528 1.98988633694654 0.00573657258300603 0.0428889262434633 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 6/2651 13/18639 0.461538461538462 3.24504541102051 0.00574993901999854 0.0428889262434633 GO:0008175 tRNA methyltransferase activity 11/2651 34/18639 0.323529411764706 2.27471320478399 0.00576104804691291 0.0428889262434633 GO:0016755 aminoacyltransferase activity 91/2651 496/18639 0.183467741935484 1.28994916708242 0.00577910107856836 0.0428889262434633 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 67/2651 349/18639 0.191977077363897 1.34977772349516 0.0058691113657011 0.0432846963220456 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 8/2651 21/18639 0.380952380952381 2.67845018052487 0.00598231698870352 0.0438455530849077 GO:0004029 aldehyde dehydrogenase (NAD+) activity 7/2651 17/18639 0.411764705882353 2.89508953336144 0.00613129064517614 0.0441153839104137 GO:0016018 cyclosporin A binding 7/2651 17/18639 0.411764705882353 2.89508953336144 0.00613129064517614 0.0441153839104137 GO:0048038 quinone binding 7/2651 17/18639 0.411764705882353 2.89508953336144 0.00613129064517614 0.0441153839104137 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 12/2651 39/18639 0.307692307692308 2.16336360734701 0.00628566240193652 0.0449520099047582 GO:0008187 poly-pyrimidine tract binding 10/2651 30/18639 0.333333333333333 2.34364390795926 0.00659701391066784 0.0463317281106284 GO:0035925 mRNA 3'-UTR AU-rich region binding 10/2651 30/18639 0.333333333333333 2.34364390795926 0.00659701391066784 0.0463317281106284 GO:0001046 core promoter sequence-specific DNA binding 13/2651 44/18639 0.295454545454545 2.07732073660025 0.0066330725595598 0.0463317281106284 GO:0031490 chromatin DNA binding 29/2651 128/18639 0.2265625 1.59294546869106 0.00663564580567474 0.0463317281106284 GO:0140463 chromatin-protein adaptor activity 15/2651 54/18639 0.277777777777778 1.95303658996605 0.00692022624823832 0.0480345116054189 GO:0000175 3'-5'-RNA exonuclease activity 11/2651 35/18639 0.314285714285714 2.20972139893302 0.00734164140864944 0.0506616190772301 GO:0008239 dipeptidyl-peptidase activity 5/2651 10/18639 0.5 3.51546586193889 0.00782927037749357 0.0527916516882424 GO:0008641 ubiquitin-like modifier activating enzyme activity 5/2651 10/18639 0.5 3.51546586193889 0.00782927037749357 0.0527916516882424 GO:0016783 sulfurtransferase activity 5/2651 10/18639 0.5 3.51546586193889 0.00782927037749357 0.0527916516882424 GO:0097177 mitochondrial ribosome binding 5/2651 10/18639 0.5 3.51546586193889 0.00782927037749357 0.0527916516882424 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 7/2651 18/18639 0.388888888888889 2.73425122595247 0.00881790674613516 0.0581292176560865 GO:0035615 clathrin adaptor activity 7/2651 18/18639 0.388888888888889 2.73425122595247 0.00881790674613516 0.0581292176560865 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 7/2651 18/18639 0.388888888888889 2.73425122595247 0.00881790674613516 0.0581292176560865 GO:1901611 phosphatidylglycerol binding 7/2651 18/18639 0.388888888888889 2.73425122595247 0.00881790674613516 0.0581292176560865 GO:0055106 ubiquitin-protein transferase regulator activity 11/2651 36/18639 0.305555555555556 2.14834024896266 0.00924046044742961 0.0605763518220385 GO:0051059 NF-kappaB binding 10/2651 32/18639 0.3125 2.19716616371181 0.0108451161480531 0.0703144893115533 GO:0140142 nucleocytoplasmic carrier activity 10/2651 32/18639 0.3125 2.19716616371181 0.0108451161480531 0.0703144893115533 GO:0004402 histone acetyltransferase activity 12/2651 42/18639 0.285714285714286 2.00883763539365 0.0118382065548431 0.0763337909000814 GO:0061749 forked DNA-dependent helicase activity 13/2651 47/18639 0.276595744680851 1.94472579596619 0.0119447915514782 0.0766024675583931 GO:0008301 DNA binding, bending 7/2651 19/18639 0.368421052631579 2.59034326669181 0.0122756210561901 0.0774954018160379 GO:0000510 H3-H4 histone complex chaperone activity 32/2651 151/18639 0.211920529801325 1.48999877592112 0.0124123991044332 0.0774954018160379 GO:0140584 chromatin extrusion motor activity 32/2651 151/18639 0.211920529801325 1.48999877592112 0.0124123991044332 0.0774954018160379 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 32/2651 151/18639 0.211920529801325 1.48999877592112 0.0124123991044332 0.0774954018160379 GO:0140849 ATP-dependent H2AZ histone chaperone activity 32/2651 151/18639 0.211920529801325 1.48999877592112 0.0124123991044332 0.0774954018160379 GO:0008526 phosphatidylinositol transfer activity 5/2651 11/18639 0.454545454545455 3.19587805630808 0.0126890791092982 0.0783932636071826 GO:0019206 nucleoside kinase activity 5/2651 11/18639 0.454545454545455 3.19587805630808 0.0126890791092982 0.0783932636071826 GO:1990841 promoter-specific chromatin binding 17/2651 68/18639 0.25 1.75773293096945 0.0128001323996402 0.0786674803727888 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/2651 15/18639 0.4 2.81237268955111 0.013020963436135 0.0796100355162659 GO:0015616 DNA translocase activity 32/2651 152/18639 0.210526315789474 1.48019615239532 0.0136362648608044 0.0825168847987141 GO:0140674 ATP-dependent histone chaperone activity 32/2651 152/18639 0.210526315789474 1.48019615239532 0.0136362648608044 0.0825168847987141 GO:0140658 ATP-dependent chromatin remodeler activity 33/2651 158/18639 0.208860759493671 1.46848573979726 0.0139075270922835 0.0837289896372168 GO:0034212 protein N-acetyltransferase activity 14/2651 53/18639 0.264150943396226 1.85722724781677 0.0140791539337861 0.0843242309023606 GO:0042162 telomeric DNA binding 11/2651 38/18639 0.289473684210526 2.03526970954357 0.0141493201005656 0.0843242309023606 GO:0009378 four-way junction helicase activity 13/2651 48/18639 0.270833333333333 1.9042106752169 0.0143012879842364 0.084377599106995 GO:0016879 ligase activity, forming carbon-nitrogen bonds 13/2651 48/18639 0.270833333333333 1.9042106752169 0.0143012879842364 0.084377599106995 GO:0061775 cohesin loader activity 32/2651 153/18639 0.209150326797386 1.47052166773914 0.0149558814048218 0.0878006968044267 GO:0016779 nucleotidyltransferase activity 29/2651 136/18639 0.213235294117647 1.49924279406217 0.015383590755892 0.0898645400591712 GO:0019887 protein kinase regulator activity 49/2651 255/18639 0.192156862745098 1.35104178223534 0.0162346835649515 0.0943690965844473 GO:0016408 C-acyltransferase activity 7/2651 20/18639 0.35 2.46082610335722 0.0166116056572449 0.0951538576482958 GO:0061608 nuclear import signal receptor activity 7/2651 20/18639 0.35 2.46082610335722 0.0166116056572449 0.0951538576482958 GO:0140939 histone H4 methyltransferase activity 7/2651 20/18639 0.35 2.46082610335722 0.0166116056572449 0.0951538576482958 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 10/2651 34/18639 0.294117647058824 2.06792109525817 0.0168958225622889 0.0959664343795635 GO:0016763 pentosyltransferase activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.0959664343795635 GO:0060590 ATPase regulator activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.0959664343795635 GO:0004722 protein serine/threonine phosphatase activity 23/2651 103/18639 0.223300970873786 1.57001388008921 0.0171350071726095 0.0962824212556155 GO:0016790 thiolester hydrolase activity 12/2651 44/18639 0.272727272727273 1.91752683378485 0.0172396253965999 0.0964111752037342 GO:0019207 kinase regulator activity 54/2651 287/18639 0.18815331010453 1.32289307696655 0.0179888028007099 0.100126355211499 GO:0008170 N-methyltransferase activity 22/2651 98/18639 0.224489795918367 1.5783724278093 0.0183169869275803 0.101294761249542 GO:0000062 fatty-acyl-CoA binding 6/2651 16/18639 0.375 2.63659939645417 0.0183704058537305 0.101294761249542 GO:0017056 structural constituent of nuclear pore 8/2651 25/18639 0.32 2.24989815164089 0.0188677505644623 0.103553235656118 GO:0004300 enoyl-CoA hydratase activity 5/2651 12/18639 0.416666666666667 2.92955488494908 0.01924115198476 0.10462930572358 GO:0017166 vinculin binding 5/2651 12/18639 0.416666666666667 2.92955488494908 0.01924115198476 0.10462930572358 GO:0004519 endonuclease activity 27/2651 127/18639 0.21259842519685 1.49476501216299 0.0195798668711397 0.105982765632775 GO:0051721 protein phosphatase 2A binding 9/2651 30/18639 0.3 2.10927951716333 0.0201417197447699 0.108526161181865 GO:0010485 histone H4 acetyltransferase activity 10/2651 35/18639 0.285714285714286 2.00883763539365 0.0207174950237447 0.11057717018947 GO:0061791 GTPase motor activity 11/2651 40/18639 0.275 1.93350622406639 0.0208035015102223 0.11057717018947 GO:1990606 membrane scission GTPase motor activity 11/2651 40/18639 0.275 1.93350622406639 0.0208035015102223 0.11057717018947 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 44/2651 229/18639 0.192139737991266 1.35092137926036 0.0218176290449787 0.114990999955504 GO:0016410 N-acyltransferase activity 21/2651 94/18639 0.223404255319149 1.5707400659727 0.0219224989105784 0.114990999955504 GO:0140312 cargo adaptor activity 7/2651 21/18639 0.333333333333333 2.34364390795926 0.0219262499915156 0.114990999955504 GO:0019212 phosphatase inhibitor activity 14/2651 56/18639 0.25 1.75773293096945 0.0225987899461778 0.117993682019866 GO:0043130 ubiquitin binding 22/2651 100/18639 0.22 1.54680497925311 0.0228365785611789 0.118709967851062 GO:0005048 signal sequence binding 13/2651 51/18639 0.254901960784314 1.79219828255708 0.0235206916982872 0.121321545315844 GO:0042054 histone methyltransferase activity 16/2651 67/18639 0.238805970149254 1.6790284713738 0.0235446049807868 0.121321545315844 GO:0120014 phospholipid transfer activity 8/2651 26/18639 0.307692307692308 2.16336360734701 0.0239409945415032 0.122827711125973 GO:0004842 ubiquitin-protein transferase activity 79/2651 449/18639 0.175946547884187 1.23706816522571 0.024972417769557 0.125128489991724 GO:0032183 SUMO binding 6/2651 17/18639 0.352941176470588 2.48150531430981 0.0250462868765783 0.125128489991724 GO:0070403 NAD+ binding 6/2651 17/18639 0.352941176470588 2.48150531430981 0.0250462868765783 0.125128489991724 GO:1901567 fatty acid derivative binding 6/2651 17/18639 0.352941176470588 2.48150531430981 0.0250462868765783 0.125128489991724 GO:1990226 histone methyltransferase binding 6/2651 17/18639 0.352941176470588 2.48150531430981 0.0250462868765783 0.125128489991724 GO:0000993 RNA polymerase II complex binding 10/2651 36/18639 0.277777777777778 1.95303658996605 0.0251317390915582 0.125128489991724 GO:0044390 ubiquitin-like protein conjugating enzyme binding 10/2651 36/18639 0.277777777777778 1.95303658996605 0.0251317390915582 0.125128489991724 GO:0043539 protein serine/threonine kinase activator activity 17/2651 73/18639 0.232876712328767 1.63734026446469 0.0252717277961778 0.125296801678529 GO:0004601 peroxidase activity 14/2651 57/18639 0.245614035087719 1.72689551112788 0.0261549253211412 0.129133104096011 GO:0008253 5'-nucleotidase activity 5/2651 13/18639 0.384615384615385 2.70420450918376 0.027673160087736 0.135495140678541 GO:0043560 insulin receptor substrate binding 5/2651 13/18639 0.384615384615385 2.70420450918376 0.027673160087736 0.135495140678541 GO:0061733 protein-lysine-acetyltransferase activity 12/2651 47/18639 0.25531914893617 1.7951315039688 0.028546527693138 0.139193812718607 GO:0051879 Hsp90 protein binding 11/2651 42/18639 0.261904761904762 1.84143449911085 0.0295104468740705 0.143301758483141 GO:0070717 poly-purine tract binding 9/2651 32/18639 0.28125 1.97744954734063 0.0303942468246046 0.146851758057409 GO:0008080 N-acetyltransferase activity 16/2651 69/18639 0.231884057971014 1.63036097944992 0.0304904073932756 0.146851758057409 GO:0016209 antioxidant activity 19/2651 86/18639 0.22093023255814 1.55334538085672 0.0314493659389286 0.15085468214608 GO:0004864 protein phosphatase inhibitor activity 13/2651 53/18639 0.245283018867925 1.724568158687 0.0317325051419958 0.151596583269454 GO:0098641 cadherin binding involved in cell-cell adhesion 6/2651 18/18639 0.333333333333333 2.34364390795926 0.0331604769417998 0.157779688674693 GO:0042826 histone deacetylase binding 26/2651 127/18639 0.204724409448819 1.43940334504585 0.0334846878817377 0.158682456628315 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 14/2651 59/18639 0.23728813559322 1.66835668024219 0.0344799377165725 0.161453676609347 GO:0036002 pre-mRNA binding 14/2651 59/18639 0.23728813559322 1.66835668024219 0.0344799377165725 0.161453676609347 GO:0070063 RNA polymerase binding 14/2651 59/18639 0.23728813559322 1.66835668024219 0.0344799377165725 0.161453676609347 GO:0004602 glutathione peroxidase activity 7/2651 23/18639 0.304347826086957 2.13984878552802 0.035841272143023 0.167164826595918 GO:0046982 protein heterodimerization activity 65/2651 369/18639 0.176151761517615 1.23851100827115 0.0380118761384826 0.17572091813775 GO:0030983 mismatched DNA binding 5/2651 14/18639 0.357142857142857 2.51104704424207 0.0381225042739525 0.17572091813775 GO:1990825 sequence-specific mRNA binding 5/2651 14/18639 0.357142857142857 2.51104704424207 0.0381225042739525 0.17572091813775 GO:0003724 RNA helicase activity 17/2651 77/18639 0.220779220779221 1.55228362734964 0.0405385842840899 0.186130464806327 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.189302303275401 GO:0031996 thioesterase binding 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.189302303275401 GO:0033204 ribonuclease P RNA binding 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.189302303275401 GO:0098505 G-rich strand telomeric DNA binding 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.189302303275401 GO:1905394 retromer complex binding 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.189302303275401 GO:0120227 acyl-CoA binding 6/2651 19/18639 0.315789473684211 2.22029422859298 0.0427996411966966 0.192028808411034 GO:0051020 GTPase binding 56/2651 315/18639 0.177777777777778 1.24994341757827 0.0439237556280348 0.196299785879697 GO:0042625 ATPase-coupled ion transmembrane transporter activity 7/2651 24/18639 0.291666666666667 2.05068841946435 0.0445833411997956 0.196299785879697 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 7/2651 24/18639 0.291666666666667 2.05068841946435 0.0445833411997956 0.196299785879697 GO:0046961 proton-transporting ATPase activity, rotational mechanism 7/2651 24/18639 0.291666666666667 2.05068841946435 0.0445833411997956 0.196299785879697 GO:0070300 phosphatidic acid binding 7/2651 24/18639 0.291666666666667 2.05068841946435 0.0445833411997956 0.196299785879697 GO:0016922 nuclear receptor binding 27/2651 137/18639 0.197080291970803 1.38565807696861 0.046974968563091 0.20606120038828 GO:0016791 phosphatase activity 49/2651 273/18639 0.179487179487179 1.26196210428576 0.0489136801692932 0.213770898517652 GO:0008186 ATP-dependent activity, acting on RNA 17/2651 79/18639 0.215189873417722 1.5129853076699 0.0502698874985682 0.217434415045732 GO:0004865 protein serine/threonine phosphatase inhibitor activity 5/2651 15/18639 0.333333333333333 2.34364390795926 0.0506732746928612 0.217434415045732 GO:0008252 nucleotidase activity 5/2651 15/18639 0.333333333333333 2.34364390795926 0.0506732746928612 0.217434415045732 GO:0015556 C4-dicarboxylate transmembrane transporter activity 5/2651 15/18639 0.333333333333333 2.34364390795926 0.0506732746928612 0.217434415045732 GO:0045504 dynein heavy chain binding 5/2651 15/18639 0.333333333333333 2.34364390795926 0.0506732746928612 0.217434415045732 GO:0016830 carbon-carbon lyase activity 12/2651 51/18639 0.235294117647059 1.65433687620654 0.0508620701513966 0.217453778183507 GO:0140566 histone reader activity 9/2651 35/18639 0.257142857142857 1.80795387185429 0.0518009911015653 0.220668481948906 GO:0004721 phosphoprotein phosphatase activity 33/2651 175/18639 0.188571428571429 1.32583283935981 0.0529250947824336 0.224646085767164 GO:0016769 transferase activity, transferring nitrogenous groups 8/2651 30/18639 0.266666666666667 1.87491512636741 0.0536163330023968 0.226394425159527 GO:0000339 RNA cap binding 6/2651 20/18639 0.3 2.10927951716333 0.0540230849993189 0.226394425159527 GO:0035064 methylated histone binding 16/2651 74/18639 0.216216216216216 1.52020145381141 0.0542722403115359 0.226394425159527 GO:0008139 nuclear localization sequence binding 7/2651 25/18639 0.28 1.96866088268578 0.0545838486690919 0.226394425159527 GO:0008483 transaminase activity 7/2651 25/18639 0.28 1.96866088268578 0.0545838486690919 0.226394425159527 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 7/2651 25/18639 0.28 1.96866088268578 0.0545838486690919 0.226394425159527 GO:0017124 SH3 domain binding 23/2651 115/18639 0.2 1.40618634477556 0.0546800094664958 0.226394425159527 GO:0140318 protein transporter activity 10/2651 41/18639 0.24390243902439 1.71486139606775 0.0574756415740673 0.236799992512832 GO:0002039 p53 binding 15/2651 69/18639 0.217391304347826 1.5284634182343 0.0586055834857223 0.236799992512832 GO:0004523 RNA-DNA hybrid ribonuclease activity 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.236799992512832 GO:0015217 ADP transmembrane transporter activity 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.236799992512832 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.236799992512832 GO:0019107 myristoyltransferase activity 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.236799992512832 GO:0032404 mismatch repair complex binding 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.236799992512832 GO:0140031 phosphorylation-dependent protein binding 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.236799992512832 GO:0005484 SNAP receptor activity 9/2651 36/18639 0.25 1.75773293096945 0.0606907417715676 0.243588691464115 GO:0008327 methyl-CpG binding 8/2651 31/18639 0.258064516129032 1.81443399325878 0.0636059953260742 0.254423981304297 GO:0004707 MAP kinase activity 5/2651 16/18639 0.3125 2.19716616371181 0.0653563968924662 0.257017837509945 GO:0008142 oxysterol binding 5/2651 16/18639 0.3125 2.19716616371181 0.0653563968924662 0.257017837509945 GO:0008296 3'-5'-DNA exonuclease activity 5/2651 16/18639 0.3125 2.19716616371181 0.0653563968924662 0.257017837509945 GO:0017070 U6 snRNA binding 5/2651 16/18639 0.3125 2.19716616371181 0.0653563968924662 0.257017837509945 GO:0030275 LRR domain binding 5/2651 16/18639 0.3125 2.19716616371181 0.0653563968924662 0.257017837509945 GO:0004529 DNA exonuclease activity 7/2651 26/18639 0.269230769230769 1.89294315642863 0.0658733212424141 0.257017837509945 GO:0070006 metalloaminopeptidase activity 7/2651 26/18639 0.269230769230769 1.89294315642863 0.0658733212424141 0.257017837509945 GO:0043175 RNA polymerase core enzyme binding 10/2651 42/18639 0.238095238095238 1.67403136282804 0.0662147649178162 0.257017837509945 GO:0048487 beta-tubulin binding 10/2651 42/18639 0.238095238095238 1.67403136282804 0.0662147649178162 0.257017837509945 GO:0140034 methylation-dependent protein binding 16/2651 76/18639 0.210526315789474 1.48019615239532 0.0666535015705399 0.257833158244704 GO:0072542 protein phosphatase activator activity 6/2651 21/18639 0.285714285714286 2.00883763539365 0.0668618190024402 0.257833158244704 GO:0045309 protein phosphorylated amino acid binding 13/2651 59/18639 0.220338983050847 1.54918834593917 0.0683694757956229 0.262788213155815 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 11/2651 48/18639 0.229166666666667 1.61125518672199 0.0705169006078002 0.269452198966555 GO:0160215 deacylase activity 14/2651 65/18639 0.215384615384615 1.51435452514291 0.070559940237852 0.269452198966555 GO:0019888 protein phosphatase regulator activity 21/2651 107/18639 0.196261682242991 1.37990248786386 0.0755872361391329 0.286519704751553 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 10/2651 43/18639 0.232558139534884 1.63510040090181 0.0757577524427836 0.286519704751553 GO:0048156 tau protein binding 10/2651 43/18639 0.232558139534884 1.63510040090181 0.0757577524427836 0.286519704751553 GO:0004364 glutathione transferase activity 7/2651 27/18639 0.259259259259259 1.82283415063498 0.0784648467235506 0.287062901047621 GO:0008266 poly(U) RNA binding 7/2651 27/18639 0.259259259259259 1.82283415063498 0.0784648467235506 0.287062901047621 GO:0015252 proton channel activity 7/2651 27/18639 0.259259259259259 1.82283415063498 0.0784648467235506 0.287062901047621 GO:0000340 RNA 7-methylguanosine cap binding 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:0004526 ribonuclease P activity 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:0005095 GTPase inhibitor activity 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:0016801 hydrolase activity, acting on ether bonds 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:0016803 ether hydrolase activity 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:0043047 single-stranded telomeric DNA binding 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:1990247 N6-methyladenosine-containing RNA reader activity 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.287062901047621 GO:0140035 ubiquitin-like protein reader activity 6/2651 22/18639 0.272727272727273 1.91752683378485 0.081318712408247 0.292869141261596 GO:0004860 protein kinase inhibitor activity 17/2651 84/18639 0.202380952380952 1.42292665840384 0.0814808981097633 0.292869141261596 GO:0004549 tRNA-specific ribonuclease activity 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.292869141261596 GO:0004550 nucleoside diphosphate kinase activity 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.292869141261596 GO:0004659 prenyltransferase activity 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.292869141261596 GO:0031489 myosin V binding 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.292869141261596 GO:0032977 membrane insertase activity 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.292869141261596 GO:0070402 NADPH binding 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.292869141261596 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 8/2651 33/18639 0.242424242424242 1.70446829669764 0.0868341212339942 0.308627298361787 GO:0046625 sphingolipid binding 7/2651 28/18639 0.25 1.75773293096945 0.0923541447950337 0.326332788164647 GO:0030170 pyridoxal phosphate binding 12/2651 56/18639 0.214285714285714 1.50662822654524 0.0923687722432138 0.326332788164647 GO:0016776 phosphotransferase activity, phosphate group as acceptor 9/2651 39/18639 0.230769230769231 1.62252270551026 0.0928977762361841 0.327222017787156 GO:0070577 lysine-acetylated histone binding 6/2651 23/18639 0.260869565217391 1.83415610188116 0.0973695736783259 0.341952669465549 GO:0008409 5'-3' exonuclease activity 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.345874789001608 GO:0008525 phosphatidylcholine transporter activity 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.345874789001608 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.345874789001608 GO:0016854 racemase and epimerase activity 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.345874789001608 GO:1990381 ubiquitin-specific protease binding 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.345874789001608 GO:0002161 aminoacyl-tRNA editing activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.345874789001608 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.345874789001608 GO:0030955 potassium ion binding 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.345874789001608 GO:0046975 histone H3K36 methyltransferase activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.345874789001608 GO:0019208 phosphatase regulator activity 22/2651 117/18639 0.188034188034188 1.32205553782317 0.101417522876743 0.345874789001608 GO:0070279 vitamin B6 binding 12/2651 57/18639 0.210526315789474 1.48019615239532 0.102600413896378 0.347703117539687 GO:0016279 protein-lysine N-methyltransferase activity 14/2651 69/18639 0.202898550724638 1.42656585701868 0.10493790491059 0.347703117539687 GO:0030971 receptor tyrosine kinase binding 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0033192 calmodulin-dependent protein phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0140791 histone H2AXS140 phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:1990439 MAP kinase serine/threonine phosphatase activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.347703117539687 GO:0030331 nuclear estrogen receptor binding 9/2651 40/18639 0.225 1.5819596378725 0.105489589897634 0.347703117539687 GO:0004197 cysteine-type endopeptidase activity 17/2651 88/18639 0.193181818181818 1.35824817393094 0.113999283907177 0.372688686031081 GO:0005154 epidermal growth factor receptor binding 8/2651 35/18639 0.228571428571429 1.60707010831492 0.114375687077624 0.372688686031081 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 16/2651 82/18639 0.195121951219512 1.3718891168542 0.11457575493276 0.372688686031081 GO:0033549 MAP kinase phosphatase activity 16/2651 82/18639 0.195121951219512 1.3718891168542 0.11457575493276 0.372688686031081 GO:0016278 lysine N-methyltransferase activity 14/2651 70/18639 0.2 1.40618634477556 0.114876150431086 0.372688686031081 GO:0140033 acetylation-dependent protein binding 6/2651 24/18639 0.25 1.75773293096945 0.114964984504503 0.372688686031081 GO:0016877 ligase activity, forming carbon-sulfur bonds 9/2651 41/18639 0.219512195121951 1.54337525646098 0.118993512863637 0.384691356655046 GO:0031420 alkali metal ion binding 5/2651 19/18639 0.263157894736842 1.85024519049415 0.121779430918853 0.3902513567576 GO:0097001 ceramide binding 5/2651 19/18639 0.263157894736842 1.85024519049415 0.121779430918853 0.3902513567576 GO:0140036 ubiquitin-modified protein reader activity 5/2651 19/18639 0.263157894736842 1.85024519049415 0.121779430918853 0.3902513567576 GO:0001784 phosphotyrosine residue binding 10/2651 47/18639 0.212765957446809 1.495942919974 0.122036229358944 0.3902513567576 GO:0043995 histone H4K5 acetyltransferase activity 7/2651 30/18639 0.233333333333333 1.64055073557148 0.123925571346312 0.392607991252348 GO:0043996 histone H4K8 acetyltransferase activity 7/2651 30/18639 0.233333333333333 1.64055073557148 0.123925571346312 0.392607991252348 GO:0043997 histone H4K12 acetyltransferase activity 7/2651 30/18639 0.233333333333333 1.64055073557148 0.123925571346312 0.392607991252348 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 16/2651 83/18639 0.192771084337349 1.35536033231379 0.124166072030287 0.392607991252348 GO:0004705 JUN kinase activity 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.392607991252348 GO:0005347 ATP transmembrane transporter activity 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.392607991252348 GO:0008174 mRNA methyltransferase activity 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.392607991252348 GO:0031404 chloride ion binding 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.392607991252348 GO:0061665 SUMO ligase activity 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.392607991252348 GO:0098847 sequence-specific single stranded DNA binding 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.392607991252348 GO:1901612 cardiolipin binding 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.392607991252348 GO:0019210 kinase inhibitor activity 17/2651 90/18639 0.188888888888889 1.32806488117691 0.132821288517931 0.411362520869183 GO:0019211 phosphatase activator activity 6/2651 25/18639 0.24 1.68742361373067 0.134032711610422 0.413491848538234 GO:0017018 myosin phosphatase activity 16/2651 84/18639 0.19047619047619 1.33922509026243 0.134209642364528 0.413491848538234 GO:0050661 NADP binding 11/2651 54/18639 0.203703703703704 1.43222683264177 0.136751239197063 0.420225162115973 GO:0005164 tumor necrosis factor receptor binding 7/2651 31/18639 0.225806451612903 1.58762974410143 0.141518781018882 0.433745874291637 GO:0016505 peptidase activator activity involved in apoptotic process 5/2651 20/18639 0.25 1.75773293096945 0.144364879558697 0.440182320101454 GO:0042288 MHC class I protein binding 5/2651 20/18639 0.25 1.75773293096945 0.144364879558697 0.440182320101454 GO:0019213 deacetylase activity 8/2651 37/18639 0.216216216216216 1.52020145381141 0.146049985207608 0.4441726354252 GO:0004857 enzyme inhibitor activity 67/2651 416/18639 0.161057692307692 1.1323856382207 0.149141885622068 0.452409832992392 GO:0140313 molecular sequestering activity 11/2651 55/18639 0.2 1.40618634477556 0.150242533456914 0.454579973023485 GO:1990782 protein tyrosine kinase binding 21/2651 117/18639 0.179487179487179 1.26196210428576 0.152739800124224 0.458007597715008 GO:0140789 histone phosphatase activity 24/2651 136/18639 0.176470588235294 1.2407526571549 0.15286387116597 0.458007597715008 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.458007597715008 GO:0031386 protein tag activity 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.458007597715008 GO:0042809 nuclear vitamin D receptor binding 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.458007597715008 GO:0141047 molecular tag activity 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.458007597715008 GO:0008143 poly(A) binding 6/2651 26/18639 0.230769230769231 1.62252270551026 0.154480528720825 0.458007597715008 GO:0097602 cullin family protein binding 6/2651 26/18639 0.230769230769231 1.62252270551026 0.154480528720825 0.458007597715008 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0005345 purine nucleobase transmembrane transporter activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0005528 FK506 binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0008140 cAMP response element binding protein binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0016868 intramolecular phosphotransferase activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0032356 oxidized DNA binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0043295 glutathione binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0050815 phosphoserine residue binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0099122 RNA polymerase II C-terminal domain binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0140940 histone H2A methyltransferase activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:1990259 histone H2AQ104 methyltransferase activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.458224360818238 GO:0032813 tumor necrosis factor receptor superfamily binding 10/2651 50/18639 0.2 1.40618634477556 0.1649555929553 0.471301694157999 GO:0035613 RNA stem-loop binding 5/2651 21/18639 0.238095238095238 1.67403136282804 0.168584585982528 0.480506790964693 GO:0001671 ATPase activator activity 6/2651 27/18639 0.222222222222222 1.56242927197284 0.17619929500576 0.498597525435963 GO:0008320 protein transmembrane transporter activity 6/2651 27/18639 0.222222222222222 1.56242927197284 0.17619929500576 0.498597525435963 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 6/2651 27/18639 0.222222222222222 1.56242927197284 0.17619929500576 0.498597525435963 GO:0140311 protein sequestering activity 7/2651 33/18639 0.212121212121212 1.49140975961044 0.17999626459239 0.508123426361293 GO:0030544 Hsp70 protein binding 10/2651 51/18639 0.196078431372549 1.37861406350545 0.180697149377852 0.508884573426887 GO:0004708 MAP kinase kinase activity 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.51195821639717 GO:0005159 insulin-like growth factor receptor binding 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.51195821639717 GO:0031435 mitogen-activated protein kinase kinase kinase binding 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.51195821639717 GO:0097027 ubiquitin-protein transferase activator activity 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.51195821639717 GO:0042578 phosphoric ester hydrolase activity 58/2651 363/18639 0.159779614325069 1.12339955918708 0.185455043285461 0.516124884615198 GO:0019783 ubiquitin-like protein peptidase activity 22/2651 127/18639 0.173228346456693 1.21795667657725 0.188404835016786 0.523100483105429 GO:0008093 cytoskeletal anchor activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.530831139150418 GO:0046972 histone H4K16 acetyltransferase activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.530831139150418 GO:0050321 tau-protein kinase activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.530831139150418 GO:0061980 regulatory RNA binding 11/2651 58/18639 0.189655172413793 1.33345256832165 0.194538624072583 0.530831139150418 GO:0008238 exopeptidase activity 18/2651 102/18639 0.176470588235294 1.2407526571549 0.19471005659151 0.530831139150418 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0015205 nucleobase transmembrane transporter activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0042608 T cell receptor binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0043522 leucine zipper domain binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0045294 alpha-catenin binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0050786 RAGE receptor binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:1900750 oligopeptide binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:1990948 ubiquitin ligase inhibitor activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.530831139150418 GO:0019789 SUMO transferase activity 6/2651 28/18639 0.214285714285714 1.50662822654524 0.19906615415414 0.531443578963541 GO:0036408 histone H3K14 acetyltransferase activity 6/2651 28/18639 0.214285714285714 1.50662822654524 0.19906615415414 0.531443578963541 GO:0071949 FAD binding 8/2651 40/18639 0.2 1.40618634477556 0.200517763656503 0.533437436285312 GO:0016831 carboxy-lyase activity 7/2651 34/18639 0.205882352941176 1.44754476668072 0.200717137042948 0.533437436285312 GO:0051117 ATPase binding 15/2651 84/18639 0.178571428571429 1.25552352212103 0.208053772340633 0.55169314912797 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.564285213479819 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.564285213479819 GO:0017110 nucleoside diphosphate phosphatase activity 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.564285213479819 GO:0036041 long-chain fatty acid binding 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.564285213479819 GO:0005504 fatty acid binding 9/2651 47/18639 0.191489361702128 1.3463486279766 0.217443153951684 0.568920003687332 GO:0140938 histone H3 methyltransferase activity 9/2651 47/18639 0.191489361702128 1.3463486279766 0.217443153951684 0.568920003687332 GO:0005158 insulin receptor binding 5/2651 23/18639 0.217391304347826 1.5284634182343 0.221162532083506 0.574827726560655 GO:0043274 phospholipase binding 5/2651 23/18639 0.217391304347826 1.5284634182343 0.221162532083506 0.574827726560655 GO:0044013 histone H2B acetyltransferase activity 5/2651 23/18639 0.217391304347826 1.5284634182343 0.221162532083506 0.574827726560655 GO:0010484 histone H3 acetyltransferase activity 6/2651 29/18639 0.206896551724138 1.45467552907816 0.222947738090159 0.576926164356114 GO:0106222 lncRNA binding 6/2651 29/18639 0.206896551724138 1.45467552907816 0.222947738090159 0.576926164356114 GO:0031267 small GTPase binding 45/2651 283/18639 0.159010600706714 1.1179926769417 0.230236047954495 0.5944825745871 GO:0000995 RNA polymerase III general transcription initiation factor activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0004032 aldose reductase (NADPH) activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0005049 nuclear export signal receptor activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0005165 neurotrophin receptor binding 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0005527 macrolide binding 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0016423 tRNA (guanine) methyltransferase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0035197 siRNA binding 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0036009 protein-glutamine N-methyltransferase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0070008 serine-type exopeptidase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.601630856438114 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 12/2651 67/18639 0.17910447761194 1.25927135353035 0.238103059285254 0.601630856438114 GO:0035198 miRNA binding 8/2651 42/18639 0.19047619047619 1.33922509026243 0.240726748169534 0.606960604359082 GO:0004033 aldo-keto reductase (NADPH) activity 7/2651 36/18639 0.194444444444444 1.36712561297624 0.244651389071674 0.614054349024837 GO:0000400 four-way junction DNA binding 4/2651 18/18639 0.222222222222222 1.56242927197284 0.247206742972391 0.614054349024837 GO:0031690 adrenergic receptor binding 4/2651 18/18639 0.222222222222222 1.56242927197284 0.247206742972391 0.614054349024837 GO:0070064 proline-rich region binding 4/2651 18/18639 0.222222222222222 1.56242927197284 0.247206742972391 0.614054349024837 GO:0008106 alcohol dehydrogenase (NADP+) activity 6/2651 30/18639 0.2 1.40618634477556 0.247703279776121 0.614054349024837 GO:0015215 nucleotide transmembrane transporter activity 6/2651 30/18639 0.2 1.40618634477556 0.247703279776121 0.614054349024837 GO:0031210 phosphatidylcholine binding 6/2651 30/18639 0.2 1.40618634477556 0.247703279776121 0.614054349024837 GO:0031624 ubiquitin conjugating enzyme binding 6/2651 30/18639 0.2 1.40618634477556 0.247703279776121 0.614054349024837 GO:0043998 histone H2A acetyltransferase activity 5/2651 24/18639 0.208333333333333 1.46477744247454 0.249109255130613 0.614955901786868 GO:0050699 WW domain binding 5/2651 24/18639 0.208333333333333 1.46477744247454 0.249109255130613 0.614955901786868 GO:0005548 phospholipid transporter activity 12/2651 68/18639 0.176470588235294 1.2407526571549 0.254471576098658 0.626881961996693 GO:0001222 transcription corepressor binding 9/2651 49/18639 0.183673469387755 1.29139562275306 0.255776270365535 0.628783331315275 GO:0033218 amide binding 39/2651 247/18639 0.157894736842105 1.11014711429649 0.264015203354114 0.647688024860404 GO:0070273 phosphatidylinositol-4-phosphate binding 6/2651 31/18639 0.193548387096774 1.36082549494409 0.273187559477858 0.668799419468615 GO:0001221 transcription coregulator binding 19/2651 115/18639 0.165217391304348 1.16163219785807 0.275895177337816 0.6697406338342 GO:0101005 deubiquitinase activity 19/2651 115/18639 0.165217391304348 1.16163219785807 0.275895177337816 0.6697406338342 GO:0017025 TBP-class protein binding 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.6697406338342 GO:0047617 fatty acyl-CoA hydrolase activity 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.6697406338342 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.6697406338342 GO:0005338 nucleotide-sugar transmembrane transporter activity 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.6697406338342 GO:0005542 folic acid binding 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.6697406338342 GO:0140666 annealing activity 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.6697406338342 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.6697406338342 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/2651 19/18639 0.210526315789474 1.48019615239532 0.280654026186668 0.670388159717142 GO:0042800 histone H3K4 methyltransferase activity 4/2651 19/18639 0.210526315789474 1.48019615239532 0.280654026186668 0.670388159717142 GO:0046624 sphingolipid transporter activity 4/2651 19/18639 0.210526315789474 1.48019615239532 0.280654026186668 0.670388159717142 GO:0035591 signaling adaptor activity 21/2651 129/18639 0.162790697674419 1.14457028063127 0.285961006541946 0.68168482367575 GO:0015631 tubulin binding 59/2651 385/18639 0.153246753246753 1.07746745898387 0.28659278703583 0.681813485286854 GO:0016597 amino acid binding 9/2651 51/18639 0.176470588235294 1.2407526571549 0.296072952465275 0.702949867020171 GO:0004536 DNA nuclease activity 11/2651 64/18639 0.171875 1.20844139004149 0.297205822278187 0.704222631100925 GO:0022884 macromolecule transmembrane transporter activity 6/2651 32/18639 0.1875 1.31829969822708 0.299253627552888 0.70765386876234 GO:0140299 molecular sensor activity 12/2651 71/18639 0.169014084507042 1.18832648854272 0.305723640546511 0.719375842474886 GO:0005160 transforming growth factor beta receptor binding 5/2651 26/18639 0.192307692307692 1.35210225459188 0.307258834413002 0.719375842474886 GO:0008157 protein phosphatase 1 binding 5/2651 26/18639 0.192307692307692 1.35210225459188 0.307258834413002 0.719375842474886 GO:0016289 acyl-CoA hydrolase activity 5/2651 26/18639 0.192307692307692 1.35210225459188 0.307258834413002 0.719375842474886 GO:0050750 low-density lipoprotein particle receptor binding 5/2651 26/18639 0.192307692307692 1.35210225459188 0.307258834413002 0.719375842474886 GO:0072341 modified amino acid binding 15/2651 91/18639 0.164835164835165 1.15894478965018 0.309963879342997 0.724272034900469 GO:0000217 DNA secondary structure binding 7/2651 39/18639 0.179487179487179 1.26196210428576 0.315212887748525 0.73464705858959 GO:0120013 lipid transfer activity 11/2651 65/18639 0.169230769230769 1.18984998404086 0.315649202292307 0.73464705858959 GO:0030159 signaling receptor complex adaptor activity 9/2651 52/18639 0.173076923076923 1.21689202913269 0.316789047125358 0.735848574031342 GO:0034236 protein kinase A catalytic subunit binding 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.73941007061886 GO:0044548 S100 protein binding 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.73941007061886 GO:0070742 C2H2 zinc finger domain binding 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.73941007061886 GO:0071889 14-3-3 protein binding 6/2651 33/18639 0.181818181818182 1.27835122252323 0.325755263766332 0.750764084461467 GO:0008234 cysteine-type peptidase activity 29/2651 187/18639 0.155080213903743 1.09035839568158 0.336895570294595 0.773761109291144 GO:0035255 ionotropic glutamate receptor binding 5/2651 27/18639 0.185185185185185 1.3020243933107 0.337045093369193 0.773761109291144 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 7/2651 40/18639 0.175 1.23041305167861 0.339542156495317 0.776472373380763 GO:0050997 quaternary ammonium group binding 7/2651 40/18639 0.175 1.23041305167861 0.339542156495317 0.776472373380763 GO:0005123 death receptor binding 4/2651 21/18639 0.19047619047619 1.33922509026243 0.349112601516869 0.793743487071108 GO:0010314 phosphatidylinositol-5-phosphate binding 4/2651 21/18639 0.19047619047619 1.33922509026243 0.349112601516869 0.793743487071108 GO:1904047 S-adenosyl-L-methionine binding 4/2651 21/18639 0.19047619047619 1.33922509026243 0.349112601516869 0.793743487071108 GO:0030332 cyclin binding 6/2651 34/18639 0.176470588235294 1.2407526571549 0.3525491480642 0.800015374453376 GO:0019209 kinase activator activity 23/2651 148/18639 0.155405405405405 1.09264479492695 0.356837993494864 0.808193536130402 GO:0005085 guanyl-nucleotide exchange factor activity 35/2651 230/18639 0.152173913043478 1.06992439276401 0.359821598585713 0.811546506271821 GO:0015929 hexosaminidase activity 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.811546506271821 GO:0050700 CARD domain binding 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.811546506271821 GO:0050780 dopamine receptor binding 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.811546506271821 GO:0061578 K63-linked deubiquitinase activity 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.811546506271821 GO:0046966 nuclear thyroid hormone receptor binding 5/2651 28/18639 0.178571428571429 1.25552352212103 0.367040514937683 0.821836447109044 GO:0034061 DNA polymerase activity 6/2651 35/18639 0.171428571428571 1.20530258123619 0.379496730518666 0.830387188977835 GO:0043015 gamma-tubulin binding 6/2651 35/18639 0.171428571428571 1.20530258123619 0.379496730518666 0.830387188977835 GO:0098632 cell-cell adhesion mediator activity 9/2651 55/18639 0.163636363636364 1.15051610027091 0.380381212395313 0.830387188977835 GO:0004407 histone deacetylase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0016881 acid-amino acid ligase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0032931 histone H3K56 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0033558 protein lysine deacetylase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0043992 histone H3K9 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0043993 histone H3K18 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0043994 histone H3K23 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0043999 histone H2AK5 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0044012 histone H2AK9 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0044014 histone H2BK5 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0044015 histone H2BK12 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0044016 histone H3K4 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0044017 histone H3K27 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0044018 histone H3K36 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0140908 histone H3K122 acetyltransferase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.830387188977835 GO:0016798 hydrolase activity, acting on glycosyl bonds 20/2651 130/18639 0.153846153846154 1.0816818036735 0.38891588654631 0.840514187041475 GO:0017022 myosin binding 12/2651 76/18639 0.157894736842105 1.11014711429649 0.395852515370625 0.851873845942092 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 5/2651 29/18639 0.172413793103448 1.21222960756513 0.397059843447585 0.851873845942092 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/2651 29/18639 0.172413793103448 1.21222960756513 0.397059843447585 0.851873845942092 GO:0097472 cyclin-dependent protein kinase activity 5/2651 29/18639 0.172413793103448 1.21222960756513 0.397059843447585 0.851873845942092 GO:0061659 ubiquitin-like protein ligase activity 55/2651 372/18639 0.147849462365591 1.03951947530451 0.399488114992377 0.855528086553548 GO:0034450 ubiquitin-ubiquitin ligase activity 3/2651 16/18639 0.1875 1.31829969822708 0.402887902227877 0.861245877950896 GO:0000295 adenine nucleotide transmembrane transporter activity 4/2651 23/18639 0.173913043478261 1.22277073458744 0.417708129455978 0.865599251365319 GO:0003887 DNA-directed DNA polymerase activity 4/2651 23/18639 0.173913043478261 1.22277073458744 0.417708129455978 0.865599251365319 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/2651 23/18639 0.173913043478261 1.22277073458744 0.417708129455978 0.865599251365319 GO:0030295 protein kinase activator activity 21/2651 139/18639 0.151079136690647 1.06222709497434 0.418526535466996 0.865599251365319 GO:0015605 organophosphate ester transmembrane transporter activity 8/2651 50/18639 0.16 1.12494907582045 0.418913478340422 0.865599251365319 GO:0015932 nucleobase-containing compound transmembrane transporter activity 9/2651 57/18639 0.157894736842105 1.11014711429649 0.423301599291221 0.865599251365319 GO:0000182 rDNA binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0004090 carbonyl reductase (NADPH) activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0005131 growth hormone receptor binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0005522 profilin binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0015643 toxic substance binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0016427 tRNA (cytidine) methyltransferase activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0030957 Tat protein binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0031419 cobalamin binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0042975 peroxisome proliferator activated receptor binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0043422 protein kinase B binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0045322 unmethylated CpG binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0051880 G-quadruplex DNA binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0070513 death domain binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:1990757 ubiquitin ligase activator activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:1990763 arrestin family protein binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.865599251365319 GO:0070566 adenylyltransferase activity 5/2651 30/18639 0.166666666666667 1.17182195397963 0.426931156181878 0.865599251365319 GO:0022829 wide pore channel activity 6/2651 37/18639 0.162162162162162 1.14015109035856 0.433331750195441 0.877069408628851 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.887926162519269 GO:0005092 GDP-dissociation inhibitor activity 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.887926162519269 GO:0008429 phosphatidylethanolamine binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.887926162519269 GO:0030169 low-density lipoprotein particle binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.887926162519269 GO:0046965 nuclear retinoid X receptor binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.887926162519269 GO:0051787 misfolded protein binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.887926162519269 GO:0005540 hyaluronic acid binding 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.901328133838984 GO:0035035 histone acetyltransferase binding 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.901328133838984 GO:0005310 dicarboxylic acid transmembrane transporter activity 5/2651 31/18639 0.161290322580645 1.13402124578674 0.456497232471112 0.906846354067193 GO:0047499 calcium-independent phospholipase A2 activity 5/2651 31/18639 0.161290322580645 1.13402124578674 0.456497232471112 0.906846354067193 GO:0070325 lipoprotein particle receptor binding 5/2651 31/18639 0.161290322580645 1.13402124578674 0.456497232471112 0.906846354067193 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 8/2651 52/18639 0.153846153846154 1.0816818036735 0.464490890127971 0.921175210673959 GO:0022804 active transmembrane transporter activity 66/2651 457/18639 0.144420131291028 1.01540808266069 0.466801411303006 0.922436482690539 GO:0008235 metalloexopeptidase activity 10/2651 66/18639 0.151515151515152 1.06529268543603 0.467300092435924 0.922436482690539 GO:0048306 calcium-dependent protein binding 12/2651 80/18639 0.15 1.05463975858167 0.46921199982756 0.922436482690539 GO:0002020 protease binding 20/2651 136/18639 0.147058823529412 1.03396054762909 0.473005800733088 0.922436482690539 GO:0005114 type II transforming growth factor beta receptor binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0008172 S-methyltransferase activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0008432 JUN kinase binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0010854 adenylate cyclase regulator activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0032794 GTPase activating protein binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0034056 estrogen response element binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0034713 type I transforming growth factor beta receptor binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0140537 transcription regulator activator activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.922436482690539 GO:0003746 translation elongation factor activity 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.922436482690539 GO:0004706 JUN kinase kinase kinase activity 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.922436482690539 GO:0008308 voltage-gated monoatomic anion channel activity 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.922436482690539 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.922436482690539 GO:0017128 phospholipid scramblase activity 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.922436482690539 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.922436482690539 GO:0004709 MAP kinase kinase kinase activity 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.922436482690539 GO:0042974 nuclear retinoic acid receptor binding 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.922436482690539 GO:0120020 cholesterol transfer activity 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.922436482690539 GO:0047498 calcium-dependent phospholipase A2 activity 5/2651 32/18639 0.15625 1.0985830818559 0.485616418567079 0.922436482690539 GO:0120015 sterol transfer activity 5/2651 32/18639 0.15625 1.0985830818559 0.485616418567079 0.922436482690539 GO:0030276 clathrin binding 7/2651 46/18639 0.152173913043478 1.06992439276401 0.486733766189552 0.922436482690539 GO:0030291 protein serine/threonine kinase inhibitor activity 7/2651 46/18639 0.152173913043478 1.06992439276401 0.486733766189552 0.922436482690539 GO:1901505 carbohydrate derivative transmembrane transporter activity 8/2651 53/18639 0.150943396226415 1.06127271303816 0.487015193827293 0.922436482690539 GO:0015485 cholesterol binding 8/2651 54/18639 0.148148148148148 1.04161951464856 0.509276647768257 0.947096325999874 GO:0008198 ferrous iron binding 4/2651 26/18639 0.153846153846154 1.0816818036735 0.516707885395848 0.947096325999874 GO:0015216 purine nucleotide transmembrane transporter activity 4/2651 26/18639 0.153846153846154 1.0816818036735 0.516707885395848 0.947096325999874 GO:0030507 spectrin binding 4/2651 26/18639 0.153846153846154 1.0816818036735 0.516707885395848 0.947096325999874 GO:0070412 R-SMAD binding 4/2651 26/18639 0.153846153846154 1.0816818036735 0.516707885395848 0.947096325999874 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.947096325999874 GO:0050145 nucleoside monophosphate kinase activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.947096325999874 GO:0070003 threonine-type peptidase activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.947096325999874 GO:0098631 cell adhesion mediator activity 11/2651 76/18639 0.144736842105263 1.01763485477178 0.524928054533535 0.947096325999874 GO:0003720 telomerase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0004859 phospholipase inhibitor activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0008179 adenylate cyclase binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0008603 cAMP-dependent protein kinase regulator activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0010853 cyclase activator activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0015368 calcium:monoatomic cation antiporter activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0016208 AMP binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0034452 dynactin binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0035259 nuclear glucocorticoid receptor binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0035497 cAMP response element binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0042301 phosphate ion binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0045295 gamma-catenin binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0097371 MDM2/MDM4 family protein binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0097677 STAT family protein binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:1990459 transferrin receptor binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.947096325999874 GO:0005200 structural constituent of cytoskeleton 16/2651 112/18639 0.142857142857143 1.00441881769683 0.533691619457914 0.959994071585883 GO:0030527 structural constituent of chromatin 14/2651 98/18639 0.142857142857143 1.00441881769683 0.536994561019738 0.964061660615992 GO:0042287 MHC protein binding 6/2651 41/18639 0.146341463414634 1.02891683764065 0.537586926004511 0.964061660615992 GO:0061134 peptidase regulator activity 32/2651 226/18639 0.141592920353982 0.995530155593314 0.540294055175201 0.967446107900968 GO:0051427 hormone receptor binding 5/2651 34/18639 0.147058823529412 1.03396054762909 0.542027519782018 0.967613424119185 GO:0052866 phosphatidylinositol phosphate phosphatase activity 5/2651 34/18639 0.147058823529412 1.03396054762909 0.542027519782018 0.967613424119185 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/2651 27/18639 0.148148148148148 1.04161951464856 0.547953588357005 0.976714855379556 GO:0005507 copper ion binding 9/2651 63/18639 0.142857142857143 1.00441881769683 0.549163922046351 0.977395819026687 GO:0004674 protein serine/threonine kinase activity 61/2651 433/18639 0.140877598152425 0.990500774033591 0.553882287792143 0.984308884931821 GO:0060589 nucleoside-triphosphatase regulator activity 69/2651 490/18639 0.140816326530612 0.990069977444014 0.55634349694043 0.984527164602425 GO:0016004 phospholipase activator activity 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.984527164602425 GO:0030742 GTP-dependent protein binding 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.984527164602425 GO:0004520 DNA endonuclease activity 6/2651 42/18639 0.142857142857143 1.00441881769683 0.562389796135137 0.988765173336503 GO:0004623 phospholipase A2 activity 5/2651 35/18639 0.142857142857143 1.00441881769683 0.569115984659244 0.988765173336503 GO:0003964 RNA-directed DNA polymerase activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0005172 vascular endothelial growth factor receptor binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0008035 high-density lipoprotein particle binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0035325 Toll-like receptor binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0035673 oligopeptide transmembrane transporter activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0051011 microtubule minus-end binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0061459 L-arginine transmembrane transporter activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0070700 BMP receptor binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0089720 caspase binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0097157 pre-mRNA intronic binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:1901338 catecholamine binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.988765173336503 GO:0046875 ephrin receptor binding 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.997316966910915 GO:0051019 mitogen-activated protein kinase binding 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.997316966910915 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.997316966910915 GO:0004843 cysteine-type deubiquitinase activity 15/2651 108/18639 0.138888888888889 0.976518294983025 0.581749353934153 1 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/2651 43/18639 0.13953488372093 0.981060240541086 0.58654005306643 1 GO:0008200 ion channel inhibitor activity 6/2651 43/18639 0.13953488372093 0.981060240541086 0.58654005306643 1 GO:0051428 peptide hormone receptor binding 3/2651 21/18639 0.142857142857143 1.00441881769683 0.591074076516781 1 GO:0004190 aspartic-type endopeptidase activity 5/2651 36/18639 0.138888888888889 0.976518294983025 0.595349885602982 1 GO:0045505 dynein intermediate chain binding 5/2651 36/18639 0.138888888888889 0.976518294983025 0.595349885602982 1 GO:0030695 GTPase regulator activity 68/2651 489/18639 0.139059304703476 0.97771647694006 0.600661888807904 1 GO:0106310 protein serine kinase activity 50/2651 361/18639 0.138504155124654 0.973813258154818 0.604273386905595 1 GO:0016248 channel inhibitor activity 6/2651 44/18639 0.136363636363636 0.958763416892425 0.609980991379955 1 GO:0005313 L-glutamate transmembrane transporter activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0008494 translation activator activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0019992 diacylglycerol binding 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0032036 myosin heavy chain binding 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0032454 histone H3K9 demethylase activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0071933 Arp2/3 complex binding 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 1 GO:0001618 virus receptor activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 1 GO:0001786 phosphatidylserine binding 8/2651 59/18639 0.135593220338983 0.953346674424106 0.614755277441206 1 GO:0048029 monosaccharide binding 10/2651 74/18639 0.135135135135135 0.950125908632133 0.62005551019778 1 GO:0070001 aspartic-type peptidase activity 5/2651 37/18639 0.135135135135135 0.950125908632133 0.620665219260411 1 GO:0005080 protein kinase C binding 7/2651 52/18639 0.134615384615385 0.946471578214317 0.622834019046019 1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 1 GO:0031683 G-protein beta/gamma-subunit complex binding 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 1 GO:0008237 metallopeptidase activity 25/2651 184/18639 0.135869565217391 0.955289636396438 0.630100265020618 1 GO:0140272 exogenous protein binding 11/2651 82/18639 0.134146341463415 0.943173767837263 0.631140350127513 1 GO:0141110 transporter inhibitor activity 6/2651 45/18639 0.133333333333333 0.937457563183704 0.632665405453813 1 GO:0033612 receptor serine/threonine kinase binding 4/2651 30/18639 0.133333333333333 0.937457563183704 0.634787262591535 1 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/2651 53/18639 0.132075471698113 0.928613623908386 0.64350210114452 1 GO:0030145 manganese ion binding 9/2651 68/18639 0.132352941176471 0.930564492866177 0.644912619642811 1 GO:0032934 sterol binding 9/2651 68/18639 0.132352941176471 0.930564492866177 0.644912619642811 1 GO:0140223 general transcription initiation factor activity 9/2651 68/18639 0.132352941176471 0.930564492866177 0.644912619642811 1 GO:0004089 carbonate dehydratase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0008242 omega peptidase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0010181 FMN binding 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0016846 carbon-sulfur lyase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0141050 histone H3K deacetylase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0141051 histone H4K deacetylase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 1 GO:0004725 protein tyrosine phosphatase activity 13/2651 98/18639 0.13265306122449 0.932674616432767 0.650939132219819 1 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 1 GO:0017134 fibroblast growth factor binding 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 1 GO:0061630 ubiquitin protein ligase activity 48/2651 353/18639 0.135977337110482 0.956047373218509 0.656015429923893 1 GO:0008013 beta-catenin binding 14/2651 106/18639 0.132075471698113 0.928613623908386 0.65988832864984 1 GO:0016878 acid-thiol ligase activity 4/2651 31/18639 0.129032258064516 0.907216996629391 0.661200600387154 1 GO:0072349 modified amino acid transmembrane transporter activity 4/2651 31/18639 0.129032258064516 0.907216996629391 0.661200600387154 1 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/2651 54/18639 0.12962962962963 0.91141707531749 0.663493126115453 1 GO:0035402 histone H3T11 kinase activity 33/2651 247/18639 0.133603238866397 0.93935525055857 0.679300561970312 1 GO:0097110 scaffold protein binding 9/2651 70/18639 0.128571428571429 0.903976935927143 0.679837782557716 1 GO:0004622 lysophospholipase activity 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 1 GO:0015295 solute:proton symporter activity 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 1 GO:0060229 lipase activator activity 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 1 GO:0070840 dynein complex binding 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 1 GO:0140612 DNA damage sensor activity 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 17/2651 130/18639 0.130769230769231 0.919429533122479 0.683859999076648 1 GO:0071813 lipoprotein particle binding 4/2651 32/18639 0.125 0.878866465484723 0.686284054932878 1 GO:0071814 protein-lipid complex binding 4/2651 32/18639 0.125 0.878866465484723 0.686284054932878 1 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0005149 interleukin-1 receptor binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0005521 lamin binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0015562 efflux transmembrane transporter activity 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0016722 oxidoreductase activity, acting on metal ions 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0055102 lipase inhibitor activity 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0070411 I-SMAD binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 1 GO:0032266 phosphatidylinositol-3-phosphate binding 6/2651 48/18639 0.125 0.878866465484723 0.69584025187922 1 GO:0140767 enzyme-substrate adaptor activity 18/2651 139/18639 0.129496402877698 0.910480367120864 0.70291530536486 1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 32/2651 243/18639 0.131687242798354 0.925884013020943 0.709221669879286 1 GO:0000030 mannosyltransferase activity 3/2651 25/18639 0.12 0.843711806865334 0.710994635802082 1 GO:0003707 nuclear steroid receptor activity 3/2651 25/18639 0.12 0.843711806865334 0.710994635802082 1 GO:0005537 D-mannose binding 3/2651 25/18639 0.12 0.843711806865334 0.710994635802082 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/2651 25/18639 0.12 0.843711806865334 0.710994635802082 1 GO:0001530 lipopolysaccharide binding 5/2651 41/18639 0.121951219512195 0.857430698033876 0.711919419840253 1 GO:0017080 sodium channel regulator activity 5/2651 41/18639 0.121951219512195 0.857430698033876 0.711919419840253 1 GO:0042169 SH2 domain binding 5/2651 41/18639 0.121951219512195 0.857430698033876 0.711919419840253 1 GO:0035254 glutamate receptor binding 6/2651 49/18639 0.122448979591837 0.860930415168708 0.715199776747691 1 GO:0016805 dipeptidase activity 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 1 GO:0045236 CXCR chemokine receptor binding 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 1 GO:0004676 3-phosphoinositide-dependent protein kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0004711 ribosomal protein S6 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0035175 histone H3S10 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0035979 histone H2AXS139 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0044022 histone H3S28 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0044023 histone H4S1 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0044024 histone H2AS1 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0044025 histone H2BS14 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0072354 histone H3T3 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0072371 histone H2AS121 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0072518 Rho-dependent protein serine/threonine kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0140823 histone H2BS36 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0140855 histone H3S57 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0140995 histone H2A kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0140997 histone H4 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0140998 histone H2B kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:1990244 histone H2AT120 kinase activity 32/2651 245/18639 0.130612244897959 0.918325776179955 0.726603873076768 1 GO:0019894 kinesin binding 5/2651 42/18639 0.119047619047619 0.837015681414021 0.73212612574635 1 GO:0004677 DNA-dependent protein kinase activity 32/2651 246/18639 0.130081300813008 0.914592744569468 0.735061664200057 1 GO:0140857 histone H3T45 kinase activity 32/2651 246/18639 0.130081300813008 0.914592744569468 0.735061664200057 1 GO:0051015 actin filament binding 27/2651 209/18639 0.129186602870813 0.908302184424402 0.735174609453597 1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 1 GO:0050681 nuclear androgen receptor binding 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 1 GO:0051139 metal cation:proton antiporter activity 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 11/2651 89/18639 0.123595505617978 0.868991561378153 0.737408413181484 1 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 11/2651 89/18639 0.123595505617978 0.868991561378153 0.737408413181484 1 GO:0008017 microtubule binding 36/2651 276/18639 0.130434782608696 0.91707805094058 0.738991944353256 1 GO:0019842 vitamin binding 19/2651 150/18639 0.126666666666667 0.890584685024519 0.741999886286739 1 GO:0035403 histone H3T6 kinase activity 32/2651 247/18639 0.129554655870445 0.910889939935583 0.743360991043554 1 GO:0003730 mRNA 3'-UTR binding 34/2651 262/18639 0.129770992366412 0.912410987068109 0.745033334448579 1 GO:0015172 acidic amino acid transmembrane transporter activity 2/2651 18/18639 0.111111111111111 0.78121463598642 0.748331783546764 1 GO:0017075 syntaxin-1 binding 2/2651 18/18639 0.111111111111111 0.78121463598642 0.748331783546764 1 GO:0140793 histone H2AXY142 phosphatase activity 11/2651 90/18639 0.122222222222222 0.859336099585062 0.75077800570266 1 GO:0004679 AMP-activated protein kinase activity 32/2651 248/18639 0.129032258064516 0.907216996629391 0.751499997920717 1 GO:0070888 E-box binding 7/2651 59/18639 0.11864406779661 0.834178340121093 0.752660823975988 1 GO:0023026 MHC class II protein complex binding 3/2651 27/18639 0.111111111111111 0.78121463598642 0.759884235542327 1 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 15/2651 122/18639 0.122950819672131 0.864458818509563 0.766584869596292 1 GO:0043014 alpha-tubulin binding 5/2651 44/18639 0.113636363636364 0.798969514077021 0.769397725961733 1 GO:0008574 plus-end-directed microtubule motor activity 2/2651 19/18639 0.105263157894737 0.740098076197661 0.775166007997463 1 GO:0061135 endopeptidase regulator activity 23/2651 184/18639 0.125 0.878866465484723 0.778956879708862 1 GO:0051018 protein kinase A binding 6/2651 53/18639 0.113207547169811 0.795954534778617 0.783975897027226 1 GO:0070851 growth factor receptor binding 17/2651 139/18639 0.122302158273381 0.859898124503038 0.784231891984106 1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0004935 adrenergic receptor activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0004955 prostaglandin receptor activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0005337 nucleoside transmembrane transporter activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0005381 iron ion transmembrane transporter activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0015187 glycine transmembrane transporter activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0015203 polyamine transmembrane transporter activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0031434 mitogen-activated protein kinase kinase binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0031720 haptoglobin binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0050308 sugar-phosphatase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0051864 histone H3K36 demethylase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0070097 delta-catenin binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0070739 protein-glutamic acid ligase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0070740 tubulin-glutamic acid ligase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0141109 transporter activator activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 1 GO:0023023 MHC protein complex binding 4/2651 37/18639 0.108108108108108 0.760100726905706 0.791761877135 1 GO:0042805 actinin binding 4/2651 37/18639 0.108108108108108 0.760100726905706 0.791761877135 1 GO:0016782 transferase activity, transferring sulphur-containing groups 8/2651 70/18639 0.114285714285714 0.803535054157461 0.79685136706545 1 GO:0035091 phosphatidylinositol binding 36/2651 284/18639 0.126760563380282 0.891244866407043 0.797257925381004 1 GO:0010851 cyclase regulator activity 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 1 GO:0140664 ATP-dependent DNA damage sensor activity 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 1 GO:0016417 S-acyltransferase activity 3/2651 29/18639 0.103448275862069 0.727337764539081 0.801846636736095 1 GO:0043236 laminin binding 3/2651 29/18639 0.103448275862069 0.727337764539081 0.801846636736095 1 GO:0033293 monocarboxylic acid binding 9/2651 79/18639 0.113924050632911 0.800992221707595 0.809327292208531 1 GO:0046332 SMAD binding 9/2651 79/18639 0.113924050632911 0.800992221707595 0.809327292208531 1 GO:0000099 sulfur amino acid transmembrane transporter activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0001851 complement component C3b binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0004954 prostanoid receptor activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0005225 volume-sensitive anion channel activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0008199 ferric iron binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0019203 carbohydrate phosphatase activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0019864 IgG binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0035252 UDP-xylosyltransferase activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0042285 xylosyltransferase activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0048185 activin binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0048407 platelet-derived growth factor binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0050998 nitric-oxide synthase binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0070697 activin receptor binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 1 GO:0015297 antiporter activity 16/2651 135/18639 0.118518518518519 0.833295611718848 0.818889983409483 1 GO:0001846 opsonin binding 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 1 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 1 GO:0015174 basic amino acid transmembrane transporter activity 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 1 GO:0019200 carbohydrate kinase activity 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 1 GO:0061891 calcium ion sensor activity 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 1 GO:0046906 tetrapyrrole binding 18/2651 152/18639 0.118421052631579 0.832610335722369 0.831239639196817 1 GO:0140693 molecular condensate scaffold activity 5/2651 48/18639 0.104166666666667 0.732388721237269 0.831861766176171 1 GO:0003774 cytoskeletal motor activity 18/2651 153/18639 0.117647058823529 0.827168438103269 0.839108487346476 1 GO:0032451 demethylase activity 4/2651 40/18639 0.1 0.703093172387778 0.840042004158798 1 GO:0008970 phospholipase A1 activity 2/2651 22/18639 0.0909090909090909 0.639175611261617 0.841152029770087 1 GO:0140784 metal ion sensor activity 2/2651 22/18639 0.0909090909090909 0.639175611261617 0.841152029770087 1 GO:0005078 MAP-kinase scaffold activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 1 GO:0008504 monoamine transmembrane transporter activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 1 GO:0015132 prostaglandin transmembrane transporter activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 1 GO:0015269 calcium-activated potassium channel activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 1 GO:0016840 carbon-nitrogen lyase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 1 GO:1990817 poly(A) RNA polymerase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 1 GO:0003779 actin binding 56/2651 443/18639 0.126410835214447 0.888785951551142 0.84967453651166 1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/2651 32/18639 0.09375 0.659149849113542 0.85310640499008 1 GO:0043425 bHLH transcription factor binding 3/2651 32/18639 0.09375 0.659149849113542 0.85310640499008 1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/2651 41/18639 0.0975609756097561 0.685944558427101 0.853893094355398 1 GO:0031681 G-protein beta-subunit binding 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 1 GO:0042171 lysophosphatidic acid acyltransferase activity 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 1 GO:0071617 lysophospholipid acyltransferase activity 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 1 GO:0099186 structural constituent of postsynapse 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 1 GO:0004879 nuclear receptor activity 6/2651 59/18639 0.101694915254237 0.71501000581808 0.862398952356686 1 GO:0015459 potassium channel regulator activity 6/2651 59/18639 0.101694915254237 0.71501000581808 0.862398952356686 1 GO:0004535 poly(A)-specific ribonuclease activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0008417 fucosyltransferase activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0017154 semaphorin receptor activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0019855 calcium channel inhibitor activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0031432 titin binding 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0039706 co-receptor binding 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0045159 myosin II binding 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0071714 icosanoid transmembrane transporter activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0071837 HMG box domain binding 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0140852 histone ubiquitin ligase activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 1 GO:0042056 chemoattractant activity 4/2651 42/18639 0.0952380952380952 0.669612545131217 0.866710669998455 1 GO:0140416 transcription regulator inhibitor activity 3/2651 33/18639 0.0909090909090909 0.639175611261617 0.867414557215386 1 GO:0098531 ligand-modulated transcription factor activity 6/2651 60/18639 0.1 0.703093172387778 0.872856296428844 1 GO:0020037 heme binding 16/2651 142/18639 0.112676056338028 0.792217659028483 0.873486236709425 1 GO:0005315 phosphate transmembrane transporter activity 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 1 GO:0030215 semaphorin receptor binding 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 1 GO:0050431 transforming growth factor beta binding 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/2651 34/18639 0.0882352941176471 0.620376328577451 0.880478108126778 1 GO:1902936 phosphatidylinositol bisphosphate binding 12/2651 111/18639 0.108108108108108 0.760100726905706 0.881755483182256 1 GO:0019905 syntaxin binding 6/2651 61/18639 0.0983606557377049 0.691567054807651 0.882640206147781 1 GO:0005161 platelet-derived growth factor receptor binding 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0005344 oxygen carrier activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0008392 arachidonate epoxygenase activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0008559 ABC-type xenobiotic transporter activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0042043 neurexin family protein binding 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0043176 amine binding 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 1 GO:0005543 phospholipid binding 62/2651 497/18639 0.124748490945674 0.87709812249582 0.885525738233079 1 GO:0044325 transmembrane transporter binding 15/2651 136/18639 0.110294117647059 0.775470410721814 0.886622031838512 1 GO:0001848 complement binding 2/2651 25/18639 0.08 0.562474537910223 0.889066110126847 1 GO:0015645 fatty acid ligase activity 2/2651 25/18639 0.08 0.562474537910223 0.889066110126847 1 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/2651 25/18639 0.08 0.562474537910223 0.889066110126847 1 GO:0019707 protein-cysteine S-acyltransferase activity 2/2651 25/18639 0.08 0.562474537910223 0.889066110126847 1 GO:0120515 fatty acid-CoA ligase activity 2/2651 25/18639 0.08 0.562474537910223 0.889066110126847 1 GO:0001223 transcription coactivator binding 4/2651 44/18639 0.0909090909090909 0.639175611261617 0.889464664941935 1 GO:0005544 calcium-dependent phospholipid binding 5/2651 53/18639 0.0943396226415094 0.663295445648847 0.889762592991238 1 GO:0016229 steroid dehydrogenase activity 3/2651 35/18639 0.0857142857142857 0.602651290618096 0.892382624359586 1 GO:0042277 peptide binding 29/2651 249/18639 0.116465863453815 0.818863534106248 0.899343844242944 1 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/2651 45/18639 0.0888888888888889 0.624971708789136 0.899511045324053 1 GO:0004467 long-chain fatty acid-CoA ligase activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0004953 icosanoid receptor activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0005041 low-density lipoprotein particle receptor activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0005523 tropomyosin binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0015116 sulfate transmembrane transporter activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0031005 filamin binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0034483 heparan sulfate sulfotransferase activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0051371 muscle alpha-actinin binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0120283 protein serine/threonine kinase binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0140776 protein-containing complex destabilizing activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 1 GO:0004435 phosphatidylinositol phospholipase C activity 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 1 GO:0052742 phosphatidylinositol kinase activity 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/2651 36/18639 0.0833333333333333 0.585910976989815 0.903211504651497 1 GO:0016409 palmitoyltransferase activity 3/2651 36/18639 0.0833333333333333 0.585910976989815 0.903211504651497 1 GO:0031406 carboxylic acid binding 21/2651 187/18639 0.112299465240642 0.789569872734938 0.903517258389653 1 GO:0000149 SNARE binding 11/2651 106/18639 0.10377358490566 0.729624990213732 0.903614314449886 1 GO:0008374 O-acyltransferase activity 5/2651 55/18639 0.0909090909090909 0.639175611261617 0.907595294788791 1 GO:0004180 carboxypeptidase activity 4/2651 46/18639 0.0869565217391304 0.61138536729372 0.90874268847816 1 GO:0004713 protein tyrosine kinase activity 15/2651 140/18639 0.107142857142857 0.753314113272619 0.909865499426734 1 GO:0043177 organic acid binding 21/2651 189/18639 0.111111111111111 0.78121463598642 0.912845812632147 1 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/2651 27/18639 0.0740740740740741 0.52080975732428 0.913146335278068 1 GO:0005044 scavenger receptor activity 2/2651 27/18639 0.0740740740740741 0.52080975732428 0.913146335278068 1 GO:0016405 CoA-ligase activity 2/2651 27/18639 0.0740740740740741 0.52080975732428 0.913146335278068 1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 1 GO:0008391 arachidonate monooxygenase activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 9/2651 91/18639 0.0989010989010989 0.69536687379011 0.915071644603081 1 GO:0005496 steroid binding 11/2651 108/18639 0.101851851851852 0.716113416320885 0.915583548872904 1 GO:0038024 cargo receptor activity 6/2651 65/18639 0.0923076923076923 0.649009082204103 0.915638362955002 1 GO:0043495 protein-membrane adaptor activity 4/2651 47/18639 0.0851063829787234 0.598377167989599 0.917212440109905 1 GO:0043178 alcohol binding 9/2651 92/18639 0.0978260869565217 0.687808538205435 0.921031923088641 1 GO:0004620 phospholipase activity 11/2651 109/18639 0.100917431192661 0.70954356846473 0.921082159838614 1 GO:0042887 amide transmembrane transporter activity 3/2651 38/18639 0.0789473684210526 0.555073557148246 0.921961182947257 1 GO:0005242 inward rectifier potassium channel activity 2/2651 28/18639 0.0714285714285714 0.502209408848413 0.923257772473598 1 GO:0045499 chemorepellent activity 2/2651 28/18639 0.0714285714285714 0.502209408848413 0.923257772473598 1 GO:0051119 sugar transmembrane transporter activity 2/2651 28/18639 0.0714285714285714 0.502209408848413 0.923257772473598 1 GO:0051393 alpha-actinin binding 2/2651 28/18639 0.0714285714285714 0.502209408848413 0.923257772473598 1 GO:0051959 dynein light intermediate chain binding 2/2651 28/18639 0.0714285714285714 0.502209408848413 0.923257772473598 1 GO:0141052 histone H3 demethylase activity 2/2651 28/18639 0.0714285714285714 0.502209408848413 0.923257772473598 1 GO:0005096 GTPase activator activity 31/2651 271/18639 0.114391143911439 0.804276322657606 0.923969854868622 1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 1 GO:0009881 photoreceptor activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 1 GO:0015278 intracellularly gated calcium channel activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 1 GO:0019198 transmembrane receptor protein phosphatase activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 1 GO:0045125 bioactive lipid receptor activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 1 GO:0070492 oligosaccharide binding 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 1 GO:1901981 phosphatidylinositol phosphate binding 20/2651 185/18639 0.108108108108108 0.760100726905706 0.929594628105374 1 GO:0004629 phospholipase C activity 2/2651 29/18639 0.0689655172413793 0.484891843026054 0.932251189935636 1 GO:0051861 glycolipid binding 2/2651 29/18639 0.0689655172413793 0.484891843026054 0.932251189935636 1 GO:0099604 ligand-gated calcium channel activity 2/2651 29/18639 0.0689655172413793 0.484891843026054 0.932251189935636 1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/2651 86/18639 0.0930232558139535 0.654040160360724 0.93556727441595 1 GO:0000900 mRNA regulatory element binding translation repressor activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 1 GO:0030228 lipoprotein particle receptor activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 1 GO:0032393 MHC class I receptor activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 1 GO:0034185 apolipoprotein binding 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 1 GO:0001968 fibronectin binding 2/2651 30/18639 0.0666666666666667 0.468728781591852 0.940239932829694 1 GO:0032452 histone demethylase activity 2/2651 30/18639 0.0666666666666667 0.468728781591852 0.940239932829694 1 GO:0098918 structural constituent of synapse 2/2651 30/18639 0.0666666666666667 0.468728781591852 0.940239932829694 1 GO:0008081 phosphoric diester hydrolase activity 8/2651 87/18639 0.0919540229885057 0.646522457368072 0.940457876554484 1 GO:0001727 lipid kinase activity 3/2651 41/18639 0.0731707317073171 0.514458418820326 0.943916233256299 1 GO:0140828 metal cation:monoatomic cation antiporter activity 3/2651 41/18639 0.0731707317073171 0.514458418820326 0.943916233256299 1 GO:0003756 protein disulfide isomerase activity 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 1 GO:0008381 mechanosensitive monoatomic ion channel activity 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 1 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 1 GO:0042577 lipid phosphatase activity 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 1 GO:1990380 K48-linked deubiquitinase activity 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 1 GO:0016411 acylglycerol O-acyltransferase activity 2/2651 31/18639 0.0645161290322581 0.453608498314696 0.947327734426761 1 GO:0140457 protein demethylase activity 2/2651 31/18639 0.0645161290322581 0.453608498314696 0.947327734426761 1 GO:0042626 ATPase-coupled transmembrane transporter activity 9/2651 98/18639 0.0918367346938776 0.645697811376531 0.949758082857633 1 GO:0015179 L-amino acid transmembrane transporter activity 5/2651 62/18639 0.0806451612903226 0.567010622893369 0.951642195964856 1 GO:0035173 histone kinase activity 41/2651 360/18639 0.113888888888889 0.800745001886081 0.951905145380723 1 GO:0001614 purinergic nucleotide receptor activity 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0005326 neurotransmitter transmembrane transporter activity 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0015095 magnesium ion transmembrane transporter activity 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0016502 nucleotide receptor activity 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0030627 pre-mRNA 5'-splice site binding 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0031418 L-ascorbic acid binding 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0052745 inositol phosphate phosphatase activity 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 1 GO:0016247 channel regulator activity 17/2651 168/18639 0.101190476190476 0.711463329201918 0.954865462191847 1 GO:0141003 histone H2AX kinase activity 40/2651 354/18639 0.112994350282486 0.794455562020088 0.955658882678395 1 GO:1901682 sulfur compound transmembrane transporter activity 5/2651 63/18639 0.0793650793650794 0.558010454276014 0.956067668004566 1 GO:1901681 sulfur compound binding 30/2651 275/18639 0.109090909090909 0.76701073351394 0.95672641280572 1 GO:0019239 deaminase activity 2/2651 33/18639 0.0606060606060606 0.426117074174411 0.959170098271388 1 GO:0141108 transporter regulator activity 17/2651 170/18639 0.1 0.703093172387778 0.960155630995992 1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/2651 21/18639 0.0476190476190476 0.334806272565609 0.9601901828031 1 GO:0036122 BMP binding 1/2651 21/18639 0.0476190476190476 0.334806272565609 0.9601901828031 1 GO:0051010 microtubule plus-end binding 1/2651 21/18639 0.0476190476190476 0.334806272565609 0.9601901828031 1 GO:0001540 amyloid-beta binding 7/2651 83/18639 0.0843373493975904 0.592970145387283 0.960785450098562 1 GO:0030165 PDZ domain binding 7/2651 83/18639 0.0843373493975904 0.592970145387283 0.960785450098562 1 GO:0140996 histone H3 kinase activity 40/2651 357/18639 0.112044817927171 0.787779464860256 0.961189262865424 1 GO:0051213 dioxygenase activity 8/2651 93/18639 0.0860215053763441 0.604811331086261 0.963485961832271 1 GO:0090482 vitamin transmembrane transporter activity 2/2651 34/18639 0.0588235294117647 0.413584219051634 0.964088347655427 1 GO:0140303 intramembrane lipid transporter activity 3/2651 45/18639 0.0666666666666667 0.468728781591852 0.964334751067056 1 GO:0005243 gap junction channel activity 1/2651 22/18639 0.0454545454545455 0.319587805630808 0.965858666280862 1 GO:0015377 chloride:monoatomic cation symporter activity 1/2651 22/18639 0.0454545454545455 0.319587805630808 0.965858666280862 1 GO:0033691 sialic acid binding 1/2651 22/18639 0.0454545454545455 0.319587805630808 0.965858666280862 1 GO:0016298 lipase activity 12/2651 130/18639 0.0923076923076923 0.649009082204103 0.967101773243945 1 GO:0050840 extracellular matrix binding 5/2651 67/18639 0.0746268656716418 0.524696397304312 0.970306089373649 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/2651 23/18639 0.0434782608695652 0.30569268364686 0.970720280702597 1 GO:0140103 catalytic activity, acting on a glycoprotein 1/2651 23/18639 0.0434782608695652 0.30569268364686 0.970720280702597 1 GO:0005126 cytokine receptor binding 29/2651 275/18639 0.105454545454545 0.741443709063475 0.971456596800203 1 GO:0003777 microtubule motor activity 5/2651 68/18639 0.0735294117647059 0.516980273814543 0.97312593874628 1 GO:0035401 histone H3Y41 kinase activity 10/2651 115/18639 0.0869565217391304 0.61138536729372 0.973371889457286 1 GO:0140801 histone H2AXY142 kinase activity 10/2651 115/18639 0.0869565217391304 0.61138536729372 0.973371889457286 1 GO:0004806 triacylglycerol lipase activity 1/2651 24/18639 0.0416666666666667 0.292955488494908 0.974889841073107 1 GO:0015149 hexose transmembrane transporter activity 1/2651 24/18639 0.0416666666666667 0.292955488494908 0.974889841073107 1 GO:0030552 cAMP binding 1/2651 24/18639 0.0416666666666667 0.292955488494908 0.974889841073107 1 GO:0055056 D-glucose transmembrane transporter activity 1/2651 24/18639 0.0416666666666667 0.292955488494908 0.974889841073107 1 GO:0099106 ion channel regulator activity 15/2651 160/18639 0.09375 0.659149849113542 0.975018102433795 1 GO:0030551 cyclic nucleotide binding 2/2651 37/18639 0.0540540540540541 0.380050363452853 0.97565508834624 1 GO:0005319 lipid transporter activity 17/2651 178/18639 0.0955056179775281 0.671493479246754 0.976262382010775 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/2651 25/18639 0.04 0.281237268955111 0.978465829862535 1 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 1 GO:0005227 calcium-activated cation channel activity 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 1 GO:0015145 monosaccharide transmembrane transporter activity 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 1 GO:0019865 immunoglobulin binding 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 1 GO:0030247 polysaccharide binding 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 1 GO:0034237 protein kinase A regulatory subunit binding 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 1 GO:0043548 phosphatidylinositol 3-kinase binding 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 1 GO:0015144 carbohydrate transmembrane transporter activity 2/2651 40/18639 0.05 0.351546586193889 0.983577837694312 1 GO:0005385 zinc ion transmembrane transporter activity 1/2651 27/18639 0.037037037037037 0.26040487866214 0.984162965120786 1 GO:0008227 G protein-coupled amine receptor activity 2/2651 41/18639 0.0487804878048781 0.34297227921355 0.985611766127031 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/2651 41/18639 0.0487804878048781 0.34297227921355 0.985611766127031 1 GO:0050698 proteoglycan sulfotransferase activity 1/2651 28/18639 0.0357142857142857 0.251104704424207 0.986418712996608 1 GO:0008307 structural constituent of muscle 2/2651 42/18639 0.0476190476190476 0.334806272565609 0.987399598296499 1 GO:0003785 actin monomer binding 1/2651 29/18639 0.0344827586206897 0.242445921513027 0.988353267391643 1 GO:0004181 metallocarboxypeptidase activity 1/2651 29/18639 0.0344827586206897 0.242445921513027 0.988353267391643 1 GO:0005416 amino acid:monoatomic cation symporter activity 1/2651 29/18639 0.0344827586206897 0.242445921513027 0.988353267391643 1 GO:0008375 acetylglucosaminyltransferase activity 2/2651 43/18639 0.0465116279069767 0.327020080180362 0.988970161857661 1 GO:0005506 iron ion binding 13/2651 154/18639 0.0844155844155844 0.593520210457215 0.989537065720479 1 GO:0001965 G-protein alpha-subunit binding 1/2651 30/18639 0.0333333333333333 0.234364390795926 0.990012347893779 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/2651 30/18639 0.0333333333333333 0.234364390795926 0.990012347893779 1 GO:0022839 monoatomic ion-gated channel activity 1/2651 30/18639 0.0333333333333333 0.234364390795926 0.990012347893779 1 GO:0005452 solute:inorganic anion antiporter activity 1/2651 31/18639 0.032258064516129 0.226804249157348 0.99143516834268 1 GO:0046915 transition metal ion transmembrane transporter activity 2/2651 45/18639 0.0444444444444444 0.312485854394568 0.991559034344939 1 GO:0004222 metalloendopeptidase activity 8/2651 110/18639 0.0727272727272727 0.511340489009293 0.991936556263895 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/2651 46/18639 0.0434782608695652 0.30569268364686 0.992620205585089 1 GO:0042910 xenobiotic transmembrane transporter activity 1/2651 32/18639 0.03125 0.219716616371181 0.992655362276663 1 GO:0030414 peptidase inhibitor activity 14/2651 169/18639 0.0828402366863905 0.582444048131887 0.993417305803651 1 GO:0140359 ABC-type transporter activity 2/2651 47/18639 0.0425531914893617 0.299188583994799 0.993550410447894 1 GO:0019956 chemokine binding 1/2651 33/18639 0.0303030303030303 0.213058537087206 0.993701776776828 1 GO:0030296 protein tyrosine kinase activator activity 1/2651 33/18639 0.0303030303030303 0.213058537087206 0.993701776776828 1 GO:0004866 endopeptidase inhibitor activity 13/2651 161/18639 0.0807453416149068 0.567714983915597 0.994034912618247 1 GO:0005178 integrin binding 13/2651 161/18639 0.0807453416149068 0.567714983915597 0.994034912618247 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/2651 60/18639 0.05 0.351546586193889 0.994063810699876 1 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/2651 60/18639 0.05 0.351546586193889 0.994063810699876 1 GO:0005518 collagen binding 4/2651 72/18639 0.0555555555555556 0.39060731799321 0.994402578049652 1 GO:0015020 glucuronosyltransferase activity 1/2651 34/18639 0.0294117647058824 0.206792109525817 0.99459915341687 1 GO:0019825 oxygen binding 1/2651 34/18639 0.0294117647058824 0.206792109525817 0.99459915341687 1 GO:0042562 hormone binding 6/2651 94/18639 0.0638297872340425 0.448782875992199 0.994665675483144 1 GO:0004175 endopeptidase activity 41/2651 405/18639 0.101234567901235 0.71177333500985 0.994725852217189 1 GO:0004867 serine-type endopeptidase inhibitor activity 6/2651 95/18639 0.0631578947368421 0.444058845718597 0.99519372326122 1 GO:0005343 organic acid:sodium symporter activity 1/2651 35/18639 0.0285714285714286 0.200883763539365 0.995368712368328 1 GO:0019838 growth factor binding 10/2651 136/18639 0.0735294117647059 0.516980273814543 0.995562886302081 1 GO:0005006 epidermal growth factor receptor activity 2/2651 50/18639 0.04 0.281237268955111 0.995703963791825 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/2651 36/18639 0.0277777777777778 0.195303658996605 0.996028653430012 1 GO:0005021 vascular endothelial growth factor receptor activity 2/2651 51/18639 0.0392156862745098 0.275722812701089 0.996250656434376 1 GO:0043394 proteoglycan binding 1/2651 37/18639 0.027027027027027 0.190025181726427 0.99659458579345 1 GO:0000146 microfilament motor activity 1/2651 38/18639 0.0263157894736842 0.185024519049415 0.99707989667731 1 GO:0005109 frizzled binding 1/2651 38/18639 0.0263157894736842 0.185024519049415 0.99707989667731 1 GO:0005516 calmodulin binding 17/2651 207/18639 0.0821256038647343 0.57741951355518 0.997117102599778 1 GO:0005246 calcium channel regulator activity 2/2651 53/18639 0.0377358490566038 0.265318178259539 0.997146866077846 1 GO:0017046 peptide hormone binding 2/2651 53/18639 0.0377358490566038 0.265318178259539 0.997146866077846 1 GO:0008083 growth factor activity 12/2651 162/18639 0.0740740740740741 0.52080975732428 0.99754936054789 1 GO:0015171 amino acid transmembrane transporter activity 6/2651 102/18639 0.0588235294117647 0.413584219051634 0.997713313692079 1 GO:0071855 neuropeptide receptor binding 1/2651 40/18639 0.025 0.175773293096945 0.997852945211343 1 GO:0005253 monoatomic anion channel activity 6/2651 103/18639 0.058252427184466 0.409568838284143 0.99794719499553 1 GO:0015101 organic cation transmembrane transporter activity 4/2651 81/18639 0.0493827160493827 0.347206504882853 0.998057173159818 1 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 23/2651 268/18639 0.0858208955223881 0.603400856899959 0.998247659195381 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/2651 70/18639 0.0428571428571429 0.301325645309048 0.99831122076171 1 GO:0008514 organic anion transmembrane transporter activity 23/2651 269/18639 0.0855018587360595 0.601157731037877 0.998371000617647 1 GO:0046943 carboxylic acid transmembrane transporter activity 14/2651 188/18639 0.074468085106383 0.523580021990899 0.998642029960606 1 GO:0042379 chemokine receptor binding 3/2651 72/18639 0.0416666666666667 0.292955488494908 0.998692579991985 1 GO:0005342 organic acid transmembrane transporter activity 14/2651 189/18639 0.0740740740740741 0.52080975732428 0.998754914123437 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/2651 44/18639 0.0227272727272727 0.159793902815404 0.99883938984793 1 GO:0030547 signaling receptor inhibitor activity 1/2651 44/18639 0.0227272727272727 0.159793902815404 0.99883938984793 1 GO:0008009 chemokine activity 1/2651 45/18639 0.0222222222222222 0.156242927197284 0.999004852472997 1 GO:0008201 heparin binding 12/2651 172/18639 0.0697674418604651 0.490530120270543 0.999004883901487 1 GO:0016757 glycosyltransferase activity 22/2651 267/18639 0.0823970037453183 0.579327707585435 0.999038795794673 1 GO:0015291 secondary active transmembrane transporter activity 24/2651 287/18639 0.0836236933797909 0.587952478651801 0.999160712898497 1 GO:0001217 DNA-binding transcription repressor activity 23/2651 278/18639 0.0827338129496403 0.581695790104996 0.999166468761191 1 GO:0008188 neuropeptide receptor activity 1/2651 48/18639 0.0208333333333333 0.146477744247454 0.999372711285659 1 GO:0038187 pattern recognition receptor activity 1/2651 48/18639 0.0208333333333333 0.146477744247454 0.999372711285659 1 GO:0019199 transmembrane receptor protein kinase activity 3/2651 78/18639 0.0384615384615385 0.270420450918376 0.999398050406622 1 GO:0005004 GPI-linked ephrin receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0005008 hepatocyte growth factor receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0005009 insulin receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0005011 macrophage colony-stimulating factor receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0005020 stem cell factor receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0008288 boss receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0036332 placental growth factor receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0038062 protein tyrosine kinase collagen receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0060175 brain-derived neurotrophic factor receptor activity 1/2651 49/18639 0.0204081632653061 0.143488402528118 0.999462160071723 1 GO:0015294 solute:monoatomic cation symporter activity 6/2651 116/18639 0.0517241379310345 0.36366888226954 0.999512962122691 1 GO:0005007 fibroblast growth factor receptor activity 1/2651 50/18639 0.02 0.140618634477556 0.999538857954986 1 GO:0005017 platelet-derived growth factor receptor activity 1/2651 50/18639 0.02 0.140618634477556 0.999538857954986 1 GO:0005019 platelet-derived growth factor beta-receptor activity 1/2651 50/18639 0.02 0.140618634477556 0.999538857954986 1 GO:0048020 CCR chemokine receptor binding 1/2651 50/18639 0.02 0.140618634477556 0.999538857954986 1 GO:0004497 monooxygenase activity 5/2651 106/18639 0.0471698113207547 0.331647722824424 0.999595154893076 1 GO:0005010 insulin-like growth factor receptor activity 1/2651 51/18639 0.0196078431372549 0.137861406350545 0.999604621985398 1 GO:0005030 neurotrophin receptor activity 1/2651 51/18639 0.0196078431372549 0.137861406350545 0.999604621985398 1 GO:0005539 glycosaminoglycan binding 18/2651 242/18639 0.0743801652892562 0.522961863759504 0.999645299857459 1 GO:0008236 serine-type peptidase activity 13/2651 194/18639 0.0670103092783505 0.471144909332016 0.999674336959366 1 GO:0005003 ephrin receptor activity 1/2651 53/18639 0.0188679245283019 0.132659089129769 0.99970935928903 1 GO:0005005 transmembrane-ephrin receptor activity 1/2651 53/18639 0.0188679245283019 0.132659089129769 0.99970935928903 1 GO:0008146 sulfotransferase activity 1/2651 53/18639 0.0188679245283019 0.132659089129769 0.99970935928903 1 GO:0038064 collagen receptor activity 1/2651 53/18639 0.0188679245283019 0.132659089129769 0.99970935928903 1 GO:0004252 serine-type endopeptidase activity 11/2651 176/18639 0.0625 0.439433232742361 0.999741862789762 1 GO:0017171 serine hydrolase activity 13/2651 198/18639 0.0656565656565657 0.461626830355612 0.999776741099474 1 GO:0170055 lipid transmembrane transporter activity 1/2651 56/18639 0.0178571428571429 0.125552352212103 0.999816834705331 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 11/2651 181/18639 0.0607734806629834 0.427294193163843 0.99984319739583 1 GO:0001216 DNA-binding transcription activator activity 44/2651 491/18639 0.0896130346232179 0.630063128005341 0.999866660431914 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 43/2651 484/18639 0.0888429752066116 0.624648892823852 0.99988144541529 1 GO:0015026 coreceptor activity 1/2651 61/18639 0.0163934426229508 0.115261175801275 0.999915164690406 1 GO:0015370 solute:sodium symporter activity 2/2651 79/18639 0.0253164556962025 0.177998271490577 0.999924910797585 1 GO:0019955 cytokine binding 7/2651 144/18639 0.0486111111111111 0.341781403244059 0.999925386827726 1 GO:0015293 symporter activity 7/2651 146/18639 0.0479452054794521 0.337099466213318 0.999940645221523 1 GO:0005254 chloride channel activity 2/2651 83/18639 0.0240963855421687 0.169420041539224 0.999957549158259 1 GO:0005249 voltage-gated potassium channel activity 3/2651 98/18639 0.0306122448979592 0.215232603792177 0.999957653734941 1 GO:0008509 monoatomic anion transmembrane transporter activity 7/2651 149/18639 0.0469798657718121 0.330312228638554 0.999957971257654 1 GO:0016500 protein-hormone receptor activity 1/2651 67/18639 0.0149253731343284 0.104939279460862 0.999966323387424 1 GO:0030246 carbohydrate binding 19/2651 280/18639 0.0678571428571429 0.477098938405992 0.999970470646548 1 GO:0001653 peptide receptor activity 5/2651 128/18639 0.0390625 0.274645770463976 0.999972059843723 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/2651 73/18639 0.0136986301369863 0.0963141332038052 0.999986635891697 1 GO:0008528 G protein-coupled peptide receptor activity 4/2651 122/18639 0.0327868852459016 0.23052235160255 0.999988845122832 1 GO:0099094 ligand-gated monoatomic cation channel activity 5/2651 136/18639 0.0367647058823529 0.258490136907271 0.999989742355087 1 GO:0005267 potassium channel activity 4/2651 124/18639 0.032258064516129 0.226804249157348 0.999991416543475 1 GO:0001664 G protein-coupled receptor binding 19/2651 297/18639 0.063973063973064 0.449790244961878 0.999993897373172 1 GO:0005244 voltage-gated monoatomic ion channel activity 7/2651 173/18639 0.0404624277456647 0.284488566862107 0.999997541306934 1 GO:0022832 voltage-gated channel activity 7/2651 175/18639 0.04 0.281237268955111 0.999998070016425 1 GO:0015108 chloride transmembrane transporter activity 3/2651 121/18639 0.0247933884297521 0.174320621253168 0.999998182157205 1 GO:0015103 inorganic anion transmembrane transporter activity 6/2651 165/18639 0.0363636363636364 0.255670244504647 0.99999862285013 1 GO:0022843 voltage-gated monoatomic cation channel activity 4/2651 143/18639 0.027972027972028 0.196669418849728 0.999999311995209 1 GO:0016758 hexosyltransferase activity 8/2651 197/18639 0.0406091370558376 0.285520070005189 0.999999391049786 1 GO:0008194 UDP-glycosyltransferase activity 4/2651 145/18639 0.0275862068965517 0.193956737210422 0.999999474228982 1 GO:0015079 potassium ion transmembrane transporter activity 5/2651 160/18639 0.03125 0.219716616371181 0.999999528938602 1 GO:0005262 calcium channel activity 3/2651 131/18639 0.0229007633587786 0.161013703600255 0.999999548309419 1 GO:0015085 calcium ion transmembrane transporter activity 4/2651 147/18639 0.0272108843537415 0.191317870037491 0.99999959843365 1 GO:0005179 hormone activity 3/2651 132/18639 0.0227272727272727 0.159793902815404 0.999999607281226 1 GO:0005201 extracellular matrix structural constituent 5/2651 168/18639 0.0297619047619048 0.209253920353505 0.999999834838466 1 GO:0015276 ligand-gated monoatomic ion channel activity 5/2651 186/18639 0.0268817204301075 0.189003540964457 0.999999984869407 1 GO:0022834 ligand-gated channel activity 5/2651 188/18639 0.0265957446808511 0.18699286499675 0.999999988427281 1 GO:0005125 cytokine activity 8/2651 234/18639 0.0341880341880342 0.240373734149668 0.999999993571613 1 GO:0005261 monoatomic cation channel activity 15/2651 341/18639 0.0439882697947214 0.309278521578202 0.999999999418298 1 GO:0015081 sodium ion transmembrane transporter activity 2/2651 164/18639 0.0121951219512195 0.0857430698033876 0.999999999701187 1 GO:0003823 antigen binding 2/2651 174/18639 0.0114942528735632 0.080815307171009 0.999999999932759 1 GO:0140375 immune receptor activity 1/2651 156/18639 0.00641025641025641 0.0450700751530627 0.999999999963779 1 GO:0005216 monoatomic ion channel activity 22/2651 448/18639 0.0491071428571429 0.345268968583284 0.999999999968803 1 GO:0022836 gated channel activity 11/2651 318/18639 0.0345911949685535 0.243208330071244 0.999999999975892 1 GO:0045182 translation regulator activity 11/2651 356/18639 0.0308988764044944 0.217247890344538 0.999999999999802 1 GO:0046873 metal ion transmembrane transporter activity 14/2651 450/18639 0.0311111111111111 0.218740098076198 1 1 GO:0030371 translation repressor activity 4/2651 329/18639 0.0121580547112462 0.0854824525699426 1 1